A CNS catecholaminergic cell line expresses voltage-gated currents.
A comparison of the genes coding for canonical TRP channels and their M, V and P relatives.
A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene.
A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels.
Activation of calcium channels by cAMP in STC-1 cells is dependent upon Ca2+ calmodulin-dependent protein kinase II.
Alterations in calcium channel currents underlie defective insulin secretion in a transgenic mouse.
Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells.
Ca2+ channel nanodomains boost local Ca2+ amplitude.
Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells.
Calcium entry in skeletal muscle.
Calcium sensitive non-selective cation current promotes seizure-like discharges and spreading depression in a model neuron.
Calmodulin supports both inactivation and facilitation of L-type calcium channels.
Capsaicin-induced currents with distinct desensitization and Ca2+ dependence in rat trigeminal ganglion cells.
Central Mechanisms Mediating Thrombospondin-4-induced Pain States.
Cryo-EM structure of a mitochondrial calcium uniporter.
Differential sensitivity to intracellular pH among high- and low-threshold Ca2+ currents in isolated rat CA1 neurons.
Diurnal changes in exocytosis and the number of synaptic ribbons at active zones of an ON-type bipolar cell terminal.
Dynamic regulation of sarcoplasmic reticulum Ca(2+) stores by stromal interaction molecule 1 and sarcolipin during muscle differentiation.
Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea.
Effects of hypertonia on voltage-gated ion currents in freshly isolated hippocampal neurons, and on synaptic currents in neurons in hippocampal slices.
Essential Ca(V)beta modulatory properties are AID-independent.
Existence of both fast and slow channel activity during the early stages of ventricular fibrillation.
Functionality of the TRPV subfamily of TRP ion channels: add mechano-TRP and osmo-TRP to the lexicon!
G protein-coupled receptor kinase mediates desensitization of norepinephrine-induced Ca2+ channel inhibition.
Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.
Gene expression profiles of the rat brain both immediately and 3 months following acute sarin exposure.
How irritating: the role of TRPA1 in sensing cigarette smoke and aerogenic oxidants in the airways.
Identification of ionic currents at presynaptic nerve endings of the lizard.
Inside-out Ca(2+) signalling prompted by STIM1 conformational switch.
K+ modulation of microglial superoxide production: involvement of voltage-gated Ca2+ channels.
Lambert-Eaton myasthenic syndrome: clinical diagnosis, immune-mediated mechanisms, and update on therapies.
Lambert-Eaton myasthenic syndrome: pathogenesis and treatment.
Lambert-Eaton sera reduce low-voltage and high-voltage activated Ca2+ currents in murine dorsal root ganglion neurons.
Low external NaCl concentration and low osmolarity enhance voltage-gated Ca currents but depress K currents in freshly isolated rat hippocampal neurons.
Mechanism of local and global Ca2+ sensing by calmodulin in complex with a Ca2+ channel.
Menthol preference among smokers: association with TRPA1 variants.
Molecular endpoints of Ca2+/calmodulin- and voltage-dependent inactivation of Ca(v)1.3 channels.
NADPH oxidase AtrbohD and AtrbohF genes function in ROS-dependent ABA signaling in Arabidopsis.
Neurotrophin regulation of ionic currents and cell size depends on cell context.
Neurotrophins differentially regulate voltage-gated ion channels.
Orai proteins interact with TRPC channels and confer responsiveness to store depletion.
Oxidized Phospholipid OxPAPC Activates TRPA1 and Contributes to Chronic Inflammatory Pain in Mice.
Presynaptic calcium dynamics and transmitter release evoked by single action potentials at mammalian central synapses.
Regulation of ionic channels by G proteins.
S-nitrosylation TRiPs a calcium switch.
STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle.
STIM1-Ca2+ signaling modulates automaticity of the mouse sinoatrial node.
Sarcoplasmic reticulum Ca-release channel and ATP-synthesis activities are early myocardial markers of heart failure produced by rapid ventricular pacing in dogs.
Stargazing nets new calcium channel subunit.
TRPA1: Acrolein meets its target.
The mouse C-type transient receptor potential 2 (TRPC2) channel: alternative splicing and calmodulin binding to its N terminus.
Trigeminal TRPs and the scent of pain.
Use of ionic currents to identify and estimate parameters in models of channel blockade.


This paper examines the role of financial remittances on the adaptive capacity of households in floodaffected rural communities of Upper Assam in India. Findings reveal that remittances-receiving households are likely to have better access to formal financial institutions, insurance and communication devices than nonrecipient households. This study indicates that the duration for which remittances are received by a household has a significant and positive association with structural changes made by the household to address flood impacts, farm mechanization, the household's access to borrowing, and participation in collective action on flood relief, recovery and preparedness. The adaptation potential of remittances of remittances can be realized if policy attention is given to attempts to enable gains in financial capital to be translated to gains in other types of capital and how the social element of remittances can be used to boost social capital. For example, by facilitating an increase in financial literacy and skills training, particularly among the poorer households in areas likely to be affected by the impacts of climate change and variability.


What were the causes for the Second Opium war?
Why did America enter into First World War?
What are the organs of the League of Nations?
What were the causes for the Great Economic Depression?
Write a note on National Industrial Recovery Act.
What does the term "Fascism" mean?
What were the four pillars of Fascism?
How do you say that Spirit of Nationalism is one of the causes for Second world war?
Write a note on Scorched Earth policy.
Why did America declare War on Japan?
What are the main objectives of the UNO?
Mention some of the specialized agencies of the UNO.
Mention the initial member countries of the EU.
Name the important leaders and centres of the mutiny.
Mention the importance of queen Victoria's Proclamation?
What was the immediate cause for the revolt of 1857?
Why was the not the revolt widespread?
what are the services rendered by the Arya Samaj?
What are the teaching of Vallalar?
point out the impacts of social and Religious Reform Movement in the 19 th Century.
What were the aims of Indians National Congress ?
Name some of the important moderate leaders.
Mention the importance of Lucknow session of the Indian National Congress in 1916.
Why was the Khilafat movement started?
Write a short note on the Cabinet mission.
Write a brief note on Vellore Mutiny.
What do you know about Thiruppur kumaran?
Name the papers edited by Subramaniya bharathiar in 1907.
What was Satyamurti's service as a Mayor?
Write a note on the welfare measures taken by Kamaraj?
why was Kamaraj called as "King Maker"?
Write a breif note on the rule of the Justice Party.
What are the aims of Self Respect Movement?
Mention the services rendered by Annadurai as the Chief Minister of TamilNadu.
Narrate Dr. Muthulakshmi's role in the agitation against Devadasi system.
Why do we call Periyar as "Vaikam Hero"?
Mention the importance aspects of India's policy for promoting peace.
Why is world peace an essential one?
Write a note on the policy of Apartheid.
India has rendered whole hearted suppoet to the UNO - Justify.
Give Abraham Lincoln's definition of Democracy.
Give a brief note on the functions of the Election Commission.
Name some of the religions of India.
What is net Domestic Product ?
What is meant by depreciation?
Write a note on green revolution ?
What do you know about Bhoodhan movement?
What are the main physical divisions of India?
Write any two points on the Importance of the Himalayas.
Name a few well-known holy places in the Northern Mountains of India.
Name the rivers that do not form a delta on the west coast of india.
Name the Islands belonging to India.
Mention the important hill stations of South India.
Name the factors determining the climate of India.
What do you mean by Monsoon?
Name the regions of very heavy rainfall in India.
What do you understand by the term natural resource?
What are the properties of fertile soil?
Name any four main characteristics of the tropical evergreen forest?
Name the mica producing areas of India?
What are the types of agriculture?
Name the cotton growing areas of India?
Name the factors that determine location of an industry.
What are the agrobased industries? Give examples.
Name any five software centers.
What are the by products of Jute Industry?
What is meant by pollution due to e-waste?
How does noise pollution affect mankind?
Trade, Transport and communication stand complementary to each other. How?
Write a note on suburban railway.
State the merits of pipeline transport.
What are the advantages of waterways?
Mention the four major ship building yards of india.
What are the disadvantages of ground survey?
Mention the basic components of remote sensing?
Mention any two applications of GIS.
Write any two applications of GPS?
What are the important aspects of Disaster Risk Reduction?


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text:
Board index High Culture Music
Lady Gaga, anyone?
It's only cool if no one's heard of it.
pheonixduprese
Location: Des Moines (IA)
Re: Lady Gaga, anyone?
Postby pheonixduprese » Mon Sep 13, 2010 10:40 pm UTC
But there is a consensus that the meat dress was, of course, FUCKING AWESOME, no?
Candace wrote: She's like CATNIP for BOYS! She's BOYNIP!
Lucrece
Postby Lucrece » Tue Sep 14, 2010 2:22 am UTC
She's no vocal powerhouse; she's a great musician. Great musicians are abundant, though.
That's not what you follow Lady Gaga for. It's the performance. She creates atmospheres perfectly. I recall one performance where she fights off this big angler fish like monster with tentacles that's obviously the Fame Monster, and she finishes the encounter with the iconic erupting tits&crotch.
It's exactly why you pay for a Madonna concert. Madonna is an average singer, but as an entertainer she's brilliant. And that's how Madonna and Gaga set themselves apart. They can do amazing live performances that stay fresh. Most artists when pulled live boil down to huge disappointments as it's revealed to you just how much their voice was modified in the studio.
Same with The Dresden Dolls. It's the theatrical appeal and deep interaction with the fans. Lady Gaga is particularly smart by taking her fans on a journey and making it about "the little monsters". She's affectionate, and when she wins awards like the VMA's, "we did it little monsters; we're the cool kids for once". When she's having a concert, it also becomes a pep rally. She talks to her fans, tells them they're beautiful, to stay true, to liberate themselves. When a fight broke out in one of her concerts, she stopped the music and commanded that the fighting stop and gave a speech about how her music was the antithesis of conflict.
She's interactive and caring toward her fans in a world where many people feel anonymous and unimportant.
Belial wrote: That's charming, Nancy, but all I hear when you talk is a bunch of yippy dog sounds.
Postby pheonixduprese » Tue Sep 14, 2010 2:25 am UTC
Actually, Lady Gaga is a good singer, too. Search on youtube "Vintage Lady Gaga".
I'm aware of her pre-Gaga performance. But if you're putting her on a level of an Elaine Paige, that's the gap I'm talking about.
She's a good singer, but singing isn't her signature trait. It's a greater emphasis on the performance.
True story ^. She's an overall awesome person...
WHO WEARS MEAT!!!!!
Postby bigglesworth » Tue Sep 14, 2010 9:11 am UTC
To be honest, I like most people that PETA hate.
Postby pheonixduprese » Tue Sep 14, 2010 11:48 am UTC
Especially if it involves WEARING. MEAT.
I was like that all day at school yesterday.
"So, did you watch the VMA's?"
"Oh, no, who won things?"
"I don't know, BUT LADY GAGA WORE A FUCKING MEAT DRESS!!!"
"Oh.
There's a type of meat for that?"
sophyturtle
I'll go put my shirt back on for this kind of shock. No I won't. I'll get my purse.
Location: it's turtles all the way down, even in the suburbs
Contact sophyturtle
Postby sophyturtle » Tue Sep 14, 2010 2:21 pm UTC
And she took 4 gay military escorts. Ones now excluded because of DADT. Including that cute West Point ex-cadet. She was on Maddow last night. Lady Gaga touched her.
I want to get to a place where I am neither conforming nor rebelling but simply being.
saxmaniac1987
Can't spell sex
Joined: Fri Dec 29, 2006 6:58 pm UTC
Postby saxmaniac1987 » Wed Sep 15, 2010 5:39 pm UTC
(just a little excited)
"A witty saying proves nothing" - Voltaire
Postby sophyturtle » Wed Sep 15, 2010 6:10 pm UTC
You get to see her!!!!
I would be freaking out. Just saying.
Postby pheonixduprese » Wed Sep 15, 2010 6:41 pm UTC
I'd probably be fainting about every other second.
Also, sophy, I totally got your turtle reference in your location!!!! Oh me yarm! I love that book.
Postby saxmaniac1987 » Thu Sep 16, 2010 2:22 pm UTC
So, my report: Visually and theatrically, it was fucking ridiculous. Basically the kind of set and costume changing you'd expect from, oh, a rock opera. And Philadelphia concertgoers are self-centered enough that every single time she mentioned the word Philly, the place went nuts.
I will say, though, that I was disappointed by the sound. Her singing was good, for the most part, but the sound from where I was sitting was pretty lousy. Really, really harsh sound (especially when she was using the headset mic, as opposed to the handheld one), and at times the bass was out of phase with the rest of the music. It's not the first time I've seen a show at that venue, either (I saw Muse in March), so I'm pretty sure it was just the crew. Oh well. She did Speechless with basically just piano and her belting. That was pretty awesome.

redpajama_set_name: RedPajamaCommonCrawl


Post-authoritarian transition in Southeast Europe (SEE) has proved particularly challenging for the consolidation of formal democratic politics and to the liberal transformation of the successor states, especially the post-conflict territories in Former Yugoslavia. The territories in the region span the spectrum of EU integration, from long-standing post-authoritarian Member States (Greece) and more recent post-socialist expansion of the EU (Slovenia, Croatia, Bulgaria, and Romania), to candidates and potential candidates in the Western Balkans (Bosnia, Macedonia, Montenegro, Kosovo, Albania, and Serbia).
Our network brings together several strands of politics 'at the margins' in SEE that have been largely overlooked by researchers examining the region, which include: war veterans' groups in ex-Yugoslavia; Lesbian, Gay, Bisexual, and Transgender (LGBT) activism; anti-austerity and anti-corruption protests; protests for the right to public spaces; football fan groups (so-called 'hooliganism'); far right 'extremism'; Islamism; and fringe right- and left-wing political parties.


Dark chocolate blueberry loaf - Drizzle Me Skinny!Drizzle Me Skinny!
I had lots of blueberries hanging around, seeing as they are the only berry I can find at a reasonable price right now! So I created this tasty dark chocolate blueberry loaf, with just enough chocolate to soothe that sweet crave… Makes 10 nice sized pieces at 4 smart points each.
In a large bowl beat together your egg, egg white, apple sauce, and brown sugar.
Stir in your milk and vanilla.
Hi Kate- have the points changed on this since Freestyle? Thanks!


text:
The New Americans DVD
Pricing *
This product is available from the following sellers:
Cinema Guild (for institutions)
The New Americans follows four years in the lives of a diverse group of contemporary immigrants and refugees as they journey to start new lives in America. We follow an Indian couple to Silicon Valley through the dot-com boom and bust. A Mexican meatpacker struggles to reunite his family in rural Kansas. Two families of Nigerian refugees (including the sister of slain Ogoni activist, Ken Saro-Wiwa) escape government persecution. Two Los Angeles Dodgers prospects follow their big dreams of escaping the barrios of the Dominican Republic. A Palestinian woman who marries into a new life in Chicago only to discover in the wake of September 11, she cannot leave behind the pain of her homeland's conflict. Kartemquin assembled a team of talented directors including the creators of Hoop Dreams, Who Killed Vincent Chin, and Vietnam, Long Time Coming. The detailed portraits that resulted were woven into a seven-hour miniseries that presents a kaleidoscopic picture of immigrant life and a first impression of the U.S. that few born in America can imagine.


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Marco Gonzales, former 5A Lobo, recovering from Tommy John surgery
By Neil Devlin
2016 baseball
Marco Gonzales, the former Rocky Mountain baseball pitching star in Fort Collins, has had Tommy John surgery and is recovering.
The left-hander, the only pitcher on Colorado record to win four consecutive decisions in state-championship games, missed some time in the 2015 season with elbow problems and recently decided to have the surgery and miss the rest of 2016. Various reports have him not returning to pitching until the latter part of 2017.
Gonzales was diagnosed with a partially torn ulnar collateral ligament.
Here's a link to Gonzales' Twitter account in which he recently thanked everyone for their support:
Thank you all for your kind wishes today! I can't wait to rise to this challenge ahead. pic.twitter.com/f37euU6kUi
— Marco Gonzales (@MarcoGonzales_) April 14, 2016
In the National League with St. Louis, Gonzales was 4-2 with a 4.82 earned-run average and 32 strikeouts.
As a schoolboy with the Lobos of the Class 5A Front Range League, Gonzales got the start and pitching victory in every big-school title game from 2007-10. As a junior and senior, he was All-Colorado by The Denver Post as well as player of the year in 2010, when he was 11-0, had a 2.20 ERA and struck out 87 in 54 innings. The first baseman also batted .486 with seven home runs and 36 RBIs.
He was drafted that June by the Rockies, but went on to Gonzaga and eventually was honored for his all-around abilities with the John Olerud Award, presented annually by the College Baseball Foundation to the best two-way player of the season (in 2013).
He was selected No. 19 by the Cardinals in 2013. He made his major-league debut the next year for the Cards on June 25 against the Rockies at Coors Field. He earned a no-decision.
Comments Off on Marco Gonzales, former 5A Lobo, recovering from Tommy John surgery
Categories: Baseball, Class 5A, General Preps, Prep Notebook
2A Vail Christian's Cooper Daniels clears 15 feet, 1 inch in the pole vault
Jermaine Jones of Colorado Rapids will present Sports Illustrated award to Broomfield's Porter Milner


Bob Wakelin, a talented and unique illustrator very sadly passed away earlier this year. In his memory his wife Gill Wakelin is carrying on his legacy, selling his bespoke designs worldwide, including our Winter Arts Market. Bob's prints are inspired by gaming covers, with a high quality silk finish, and his illustrations will be sold on greeting cards, t-shirts and tote bags.


Apple Watch Series 4 Worth Rs 36,000 or Hospital Bills in Lakhs?
'Prevention is Better Than Cure' is an age old saying, which technology companies now seem to be investing into and putting to use. With the launch of Apple Watch Series 4, it looks like American multinational company Apple wants to be the pioneer in preventive healthcare technology. Apart from improved specifications from Series 3, such as bigger display, 50% louder speaker, S4 dual core 64 bit processor, better mic, and improved cellular reception, Apple Watch Series 4 aims at becoming users' health guide.
Apple Watch Series 4, using its accelerometer and gyroscope, can detect falls of those wearing the device. After putting in a tremendous amount of data analysis, Apple has introduced this feature into its Series 4 while hoping users "never need this technology". Falls can cause serious damage to a person and is one of the leading causes of injuries. With the latest technology put in place, if an Apple Watch Series 4 user falls and remains immobile for 1 minute, the device will automatically call SOS. It will also send the user's location to emergency contacts.
The path breaking innovation, however, is the introduction of the Watch Series' ability to take real-time electrocardiograms of users. Apple claims that the Watch Series 4 can now detect and send notifications of a slow heart rate in addition to high heart rate. It can screen heart rhythm in the background and identify atrial fibrillation. This technology helps alert users of medical conditions that they did not know they had. This is probably the first ECG product that is being offered over the counter. ECGs can be taken anytime, anywhere by opening the app and putting user's finger on the digital crown on a real-time basis.
The watch has built in electrodes, back crystal and digital crown that detect electrical impulses from a heart beat and sends it to the S4 processor, which then coverts it into signals for Apple algorithms. The whole process takes about 30 seconds and if the heartbeat is normal, it will be called a Sinus Rhythm or else an atrial fibrillation will be indicated. Apple has received de novo clearance from the FDA for the same. Dr Ivor Benjamin, President of the American Heart Association and practicing cardiologist said at the event that it has become of utmost importance to capture meaningful data about a person on a real time basis and it is changing the way medicine is being practiced. "In my experience, patients report symptoms that are absent during a medical visit, which is why information is vital".
Cardiovascular diseases are the leading cause of death in Indians. According to a survey on The Lancet, Cardiovascular disease caused more than 2.1 million deaths in India in 2015 at all ages, which was over a quarter of all deaths caused worldwide. Total cardiovascular deaths comprised 1.3 million cardiovascular deaths at ages 30 to 69 years: 0.9 million (68·4%) from ischaemic heart disease, 0.4 million (28%) from stroke, and 47,000 (3.5%) from rheumatic heart diseases and other cardiovascular diseases.
The highest rates in 2015 were in Andhra Pradesh, Punjab, and Tamil Nadu. High stress lifestyles, high BMI (body mass index), lack of sound medical advice, high blood glucose levels, high blood pressure, and smoking too could be leading causes of deaths due to heart attacks in India.
If Apple Watch Series 4 can indeed provide accurate and real-time ECGs as it promises, then it could be an investment worth making as a simple ECG costs Indians anywhere from Rs 130 to 240 each time. Due to predictions provided by such devices, users can go for early medical intervention when a problem is detected saving them almost Rs 1.5 to 2.5 lakhs that open heart surgeries cost in India.
Not just open heart surgeries, emergency bypass surgeries are really expensive as well and may cost up to Rs 5 lakhs in premier hospitals. The Apple Watch Series 4 is pegged to cost Rs 29,000 approximately for the GPS only version, whereas the cellular and GPS version is expected to cost Rs 36,000. Although it may be a tad bit expensive, it seems prudent to invest into preventive healthcare technology that can save lives, money and valuable time provided the technology in question is really good and accurate.
Apple Watch Series 4 Worth Rs 36,000 or Hospital Bills in Lakhs? 3.75 out of 5 based on 4 ratings. 4 user reviews.