text:
In other words, patients are deprived from an already existing
In other words, patients are deprived from an already existing selleck effective therapy. The objective of testing such drugs to establish whether the new drug is better in efficacy or safety when compared to the existing drug/s placebo controlled trial considered unethical. The association of placebo effects with RCTs has caused confusion because the response in the placebo arm is not necessarily a genuine psychosocial response to the simulation of treatment. In fact, the observed response to placebo in RCTs may reflect the natural course of the disease, fluctuations in symptoms, regression to the mean, response bias with respect to the patient's reporting of subjective symptoms and other concurrent treatments.
[3,4] Clinical equipoise in placebo-controlled trials Another argument proposed against placebo-controlled trials is that they potentially violate the concept of clinical equipoise when proven effective therapy is available. Clinical equipoise refers to the state where clinicians are unsure whether the new treatment or intervention is as good as the standard treatment. Those who reject the use of placebo-controlled trials argue that they violate the therapeutic obligation of physicians to offer optimal medical care. In other words, they compromise the right of the patient to receive the best care possible and violate the ethical principle of therapeutic beneficence. Furthermore, these clinicians have argued that when proven therapy exists, the use of a placebo-controlled trial lacks both scientific and clinical merit.
[21?C23] The use of placebo is also questioned in vulnerable groups like children, psychiatric patients, and patients suffering from cancer. Ethics of placebo in children The use of placebo in children is more restricted than in adults, because children GSK-3 cannot consent. HTC Placebo should not be used when it means withholding effective treatment, particularly for serious and life-threatening conditions. The use of placebo is often needed for scientific reasons, including pediatric trials. The use of placebo may be warranted in children as in adults when evidence for any particular treatment is lacking or when the placebo effect is known to be very variable (e.g., pain, hay fever). As the level of evidence in favor of an effective treatment increases, the ethical justification for the use of placebo decreases.[24] Usefulness of placebo The use of placebo is not equivalent to the absence of treatment, for example, placebo could be used in addition to standard care. In all cases, its use should be associated with measures to minimize exposure and avoid irreversible harm, especially in serious or rapidly evolving diseases. As appropriate, rescue treatment and escape procedures should be set up.
Next, we investigated whether the variability in the A?? plaque b
Next, we investigated whether the variability in the A?? plaque burden at each age of testing also reflects inverse association with context and tone fear memory. We found that variability in A?? small molecule plaque burden (expressed by the coefficient of variation (CV)) increased with age, from 17% at three months to 34%, and 27% at six and 12 months, respectively. Moreover, the variability in memory scores of CRND8 mice differed from the variability in memory of nTg littermates. While the variance in memory scores of nTg mice was low and comparable across age groups (73%, 76%, 60%, and 38%, 49%, 50% for three, six, and 12 month context and tone memory, respectively), the variability in memory scores of CRND8 mice was higher, reaching high variance (CV > 100%) at the age of 12 months (70%, 93%, 144%, and 53%, 75%, 113% for three, six, and 12 month context and tone memory, respectively).
While our analysis revealed no significant association between the A?? plaque burden and the context fear memory in CRND8 mice at any age of testing, surprisingly, we found positive associations between A?? plaque burden and tone fear memory at three (rS = 0.67, P < 0.05) and six months of age (rS = 0.80, P < 0.01), but not at 12 months of age (rS = 0.30, NS). Despite a much reduced sample size, these post-hoc analyses revealed that at the ages of three and six months, which are characterized by rapid A?? plaque formation, those CRND8 mice which showed more A?? plaques, also showed higher tone fear memory. At present, these preliminary results have to be interpreted with caution.
These findings should be replicated in future studies and the relationship between the soluble A?? and A?? sequestered in plaques, and also other processes, such as reactive gliosis and inflammatory responses should be systematically evaluated in order to elucidate further the relationship between amyloid-?? and cognition at the early stage of plaque formation. Discussion The present results extend previous studies showing that other APP mouse models exhibit impairment in fear conditioned memory, by demonstrating that this impairment is progressive and correlates well with overall A?? burden. Also, the demonstrated greater sensitivity of the foreground tone conditioning test in the identification of age dependent onset of the memory impairment in CRND8, suggests that this testing paradigm might be particularly suitable in studies evaluating potential AV-951 therapeutic agents related to memory improvement in APP mouse models.
APP transgenic mouse models have been reported to show memory deficits similar to those observed in AD [21,48-53]. However, comprehensive cognitive profiles, including multiple memory systems, have often been based on comparative analyses from several independent clearly studies using APP mouse models (see [21]).
Each transgenic mouse model of AD provides different insights int
Each transgenic mouse model of AD provides different insights into aspects of AD pathology and progression. Careful forethought is therefore required in the selection of an optimal model based on specific research interests. Our hope is that, with regard to motor and cognitive selleck chemicals deficits relating to AD, the discussion and Figure ?Figure44 presented here can help in the selection of the ideal model by providing an overview of the development and time course of behavioral deficits in the commonly used mouse models of AD. Conclusion This study is the first comprehensive behavioral analysis reported for the APP/PS1 KI mouse model of AD and the results presented here add to a growing literature for this model.
The lack of any motor/coordination deficits or abnormal anxiety levels, coupled with an age/disease-related cognitive decline and the high physiological relevance of this model, make it well suited for utilization in preclinical testing of AD-relevant therapeutics. Abbreviations AD: Alzheimer's disease; APP: amyloid precursor protein; D2: discrimination index; KI: knock-in; NADPH: nicotinamide adenine dinucleotide phosphate; NOR: novel object recognition; PS-1: presenilin-1; RAWM: radial arm water maze; WT: wild type Competing interests The authors declare that they have no competing interests. Authors' contributions SJW participated in the design of the research studies, performed the behavioral tests, and drafted the manuscript. ADB participated in the design of the study, performed the statistical analyses, and helped analyze data and draft the manuscript.
LJVE conceived of the Batimastat study, participated in its design and coordination, and helped write the manuscript. All authors read and approved the final manuscript. Acknowledgements The authors thank Danielle Goulding for maintenance of the mouse colonies and excellent technical sellekchem assistance. This research was supported in part by National Institutes of Health grants R01 NS064247 (LJVE), P01 "type":"entrez-nucleotide","attrs":"text":"AG005119″,"term_id":"2865077″,"term_text":"AG005119″AG005119 (LJVE), and F32 "type":"entrez-nucleotide","attrs":"text":"AG037280″,"term_id":"16564153″,"term_text":"AG037280″AG037280 (ADB), and by the Edward N. & Della L. Thome Memorial Foundation Awards Program in Alzheimer's Disease Drug Discovery Research (LJVE).
One of the barriers to understanding the heterogeneity in these early populations is the difficulty in isolating cognitive domains for measurement. Most neuropsychological (NP) tests require a number of cognitive processes and, therefore, measures of multiple domains.
Leachable monomers induce the
Leachable monomers induce the Carfilzomib production of intracellular reactive oxidative species (ROS) that can be generated in both healthy and diseased tissues.19,20 ROS production has been described by several investigators as an early expression of cellular stress in dental monomer cytotoxicity.20 Mohsen et al21 found that the cell viability in vitro with either untreated or polished composites correlated with the curing time of the composites by visible light and post-curing time (aging) with heat for ensuring polymerization. They also attributed the increase in the biocompatibility of the polished specimens to the removal of the oxygen-inhibited layer. The oxygen-inhibited layers allow for un-reacted double bonds at the surfaces rendering a material toxic, even with long periods of light curing.
In healthy cells, ROS can be produced by the incomplete reduction of oxygen during catabolism. The disruption of important macromolecules through free radical reactions within host cells may hamper cellular functions or may even lead to early cell death. ROS have been shown to cause disruption at multiple cellular sites, resulting in lipid peroxidation, protein oxidation and nucleic acid damage. ROS may induce cell damage directly, or act as intracellular messenger during cell death induced by various other kinds of stimuli.19 Ratanasathien et al22 assessed the cytotoxicity of the dentin- bonding components in cell cultures and found that the ranking by toxicity was: Bis-GMA>UDMA>TEGDMA>HEMA (least toxic) after 24 and 72 hours of exposure. In the same study, it was demonstrated that 0.
00360 mmol L?1 of HEMA reduced the cell metabolism by 50% after 24 h of exposure, whilst Hanks et al2 reported that 16 mmol L?1 of HEMA caused an irreversible inhibitory effect when applied to the cells in culture. HEMA is a common ingredient of dental adhesives to enhance the bond strength to dentin and is present in all adhesives evaluated in the present study (Table 1). Although HEMA was found to be less cytotoxic than the other monomers, its low molecular weight (130.14) and high solubility may result in a greater diffusion of unpolymerized HEMA through dentin. Our results concerning Gluma Comfort bond are in agreement with previous findings.1,11 Hanks et al1 examined the nature and levels of metabolic cytotoxicity of the Gluma, Scotchbond 2, glutaraldehyde and HEMA in monolayer cultures and found that glutaraldehyde was much more cytotoxic than HEMA.
Admira bond uses the so-called ��ormocer�� product, ceramic polysiloxane (silicon-oxygen chains). There have been no published studies on the cytotoxicity of Admira Bond. However, it has been reported that the ormocer restorative material, Admira, was more cytotoxic than two other conventional Dacomitinib dimethacrylate composite resins tested.23 ED Primer II and Clearfil Liner Bond 2V contain the same phosphate monomer (10-MDP), but the former proved to be significantly more cytotoxic.
Responses were given on a 5-point Likert-scale, later scored on a
Responses were given on a 5-point Likert-scale, later scored on a scale ranging from Fully agree=4 to Fully disagree=0; higher scores were for more accurate knowledge. The sum of the scores www.selleckchem.com/products/MDV3100.html described the respondent��s knowledge of preventive dental care. Those respondents with three or more missing answers were excluded (n=23); otherwise, missing answers earned a score of two (midpoint). Based on the distribution of the sum of these scores, three categories were formed: Low (<21), Medium (21�C26), and High (27�C36). Table 1 Level of knowledge of preventive dental care among Iranian dentists, assessed by nine statements on a 5-point Likert-scale, later scored as: 0=Fully disagree, 1=Disagree, 2=Don��t know, 3=Agree, and 4=Fully agree; the greater scores being for higher ...
Assessment of dentists�� attitudes toward preventive dental care Using the semantic differential method,15 a set of nine pairs of bipolar adjectives which describe preventive dentistry (Table 2) was designed to assess dentists�� attitudes towards preventive dental care. The respondents were asked to describe their attitudes towards aspects of preventive dentistry by choosing one option from a Likert-scale, ranging from 1 to 7; the higher the score, the more positive the attitudes. The sum of all scores, with a theoretical range of 9�C63, served as an indicator of respondents�� attitudes towards preventive dental care. Those respondents with three or more missing answers were excluded (n=117); otherwise, missing answers earned a score of four (midpoint).
Based on the distribution of the sum of these scores, three categories were defined: Low (<46), Medium (46�C54), and High (55�C63). Table 2 Levels of attitudes among Iranian dentists regarding preventive dentistry, assessed by nine pairs1 of bipolar adjectives, scored from 1 (indicating the least positive attitude) to 7 (indicating the most positive attitude). Dentists were to choose from ... Work-related factors included location of practice (in Tehran, the capital, or not), years in practice (years since graduation) and practice type, for which answers to the question ��What is your current job?�� were categorized as: Private solely, Private and Public, or No present clinical work. Data on dentists�� activity in continuing education was obtained by two questions.
The first, ��When was the last time you attended a continuing education course on caries prevention?��, had the response alternatives: Within Batimastat the last year, 2�C5 years ago, More than 5 years ago, Never, and Don��t know. Only those who selected first three options were included in the analysis. The second, ��Which of the following scientific dental journals do you usually read?��, had six response alternatives, later dichotomised as Extensive and Non-extensive professional reading, depending on whether the respondent reported having or not having read international scientific dental journals.
18 This study followed the guidelines recommended by Guillemin
18 This study followed the guidelines recommended by Guillemin selleck inhibitor et al.10 thus minimizing the occurrences of biases and inclinational results. This methodology made the Brazilian version of the KSS fit for application in Brazilian patients, thus making it possible to measure clinical outcomes and treatments at the same time, or through a particular follow-up. As regards semantic validity, the Brazilian adaptation of the Knee Evaluation Scale, translated and culturally adapted, demonstrated excellent semantic and conceptual equivalence, according to the results of the inter-evaluator analysis, whereas the entire process was based on the studies of Ciconelli,19 Duarte et al.17 and Guillemin et al.
10 As we were able to observe in the studies that performed the validation, it is important to supplement the translation with the sociocultural adaptation of the version for the language, in this case, Portuguese, to allow the scale to be better evaluated in the country. In the translation and validation of the original version of the KSS, only one alteration was made in the knee function score, in the item walking, in which the distance that is evaluated in Manhattan city blocks, in which a block is equal to 80 meters, was modified to distance in meters. This change is necessary as it corresponds more closely to the Brazilian situation, since blocks in Brazil are not standardized in all cities with the same measurements in meters. The sample of 70 patients divided by the number of items of the scale (5 – deductions are not considered) results in 14 subjects per item.
Kelinger20 recommends, as a general rule for the validation of instruments, the use of the largest possible sample and suggests 10 subjects per item of the instrument. In this study the participants conducted the Kaiser-Meyer-Olkin Measure of Sampling Adequacy (KMO) study, which measures the adequacy of data for the factor analysis. The KMO resulted in 0.962, which indicates that the data were optimal for the factor analysis, i.e., the sample size was adequate.11 Reliability was evaluated by internal consistency, estimated by Cronbach's alpha coefficient, for each evaluation period and in each score. We evaluated the contribution of each item to the reliability of the domains. This index can range from 0 to 1 and the higher this value, the greater the reliability of the scale.
11 All the correlations between and among items in the periods were positive and significantly different from zero, which indicates that it makes sense to form a scale with these items, as they Carfilzomib measure the same attribute: self-efficacy. The inter-evaluator reliability can be observed in Tables 2 and and3,3, in which the applications of the Knee Evaluation Scale (Knee Score and Knee Function Score) performed by evaluator 1 (questionnaire in English) and evaluator 2 (questionnaire in Portuguese) were compared in the preoperative period and at three and six months postoperatively.
When coupled with rectangular archwires, they showed significantl
When coupled with rectangular archwires, they showed significantly lower F than Damon MX? and Time3? brackets, but similar F as the Vision LP? brackets. This behavior is probably associated with their design; their elastic properties decrease when coupled with thicker archwires, resulting in low Lapatinib chemical structure F. In contrast, self-ligating brackets have a built-in metal device (to close off the edgewise slot) that is rigid and rather stiff, compared to the soft and elastic surface of low-friction ligatures. Our findings are not in agreement with the general statement that self-ligating brackets generate lower F than conventional SS brackets,2,9,14�C15,17�C18,22 probably because a variety of different self-ligating brackets were tested, each with different mechanical characteristics:19 passive or interactive slots.
The differences among the passive and interactive SL brackets could be explained by the flexibility of the spring clip of active SL brackets that can actively engage the wire also in the presence of tipping.21 In addition, in this study, no significant differences were observed between the TMA, SS, and NiTi archwires in terms of F, although it was reported that TMA generates higher F than both SS and NiTi for all bracket-archwire combinations.2,23�C30 This variability may be due to the differences in the experimental setup, number of brackets, or bracket angulations.31 Therefore, a direct comparison of various published studies on this topic is complex. One limitation of this study is that it was carried out under ideal conditions, in a passive configuration with no misalignment of brackets, as shown by previous reports.
2,9,17,20,21,24�C25,29�C30 CONCLUSIONS Self-ligating brackets appear to be a family of very different brackets. For majority of the bracket-archwire combinations, the F values obtained with all 10 brackets ligated were significantly higher than those obtained with only the terminal brackets ligated; no significant differences were observed in only 4 cases, i.e., when Damon MX? and Vision LP? brackets were engaged with round archwires. Coupled with round archwires, Damon MX? and Vision LP? brackets generated significantly lower F than Victory Series?, Time3?, and Slide? ligature brackets, while Victory Series? brackets generated significantly higher F than all the other groups.
Coupled with rectangular archwires, Victory Series? brackets, Slide? ligatures, Cilengitide and Vision LP? self-ligating brackets generated significantly lower F than Time3? and Damon MX? brackets. However, as these findings do not actually reflect the situation in clinical use wherein the periodontal ligament provides ��give,�� the possibility of making any clinical extrapolation from this study is limited.
Light emitting diode (LED) light curing units are becoming increasingly popular in dental practice. Most of the first-generation LED light units were unable to cure composite resin in the manner of quartz-tungsten-halogen (QTH) light sources.
(b) Atypical cells with mitosis (*) (Hematein-eosin �� 40) (c) S
(b) Atypical cells with mitosis (*) (Hematein-eosin �� 40). (c) Staining with anti-CD20 (��40): atypical cells are stained. (d) Staining … Figure 3 Pulmonary localisation of lymphomatoid granulomatosis. Transverse CT view, with contrast injection in parenchymatous window showing nodular lesions taking seriously contrast. (a) At initial diagnosis. (b) 2 years after reduction in the immunosuppression and rutiximab … Two months following immunosuppression reduction, the lesions were persistently unchanged. A treatment by anti-CD20 antibodies was then initiated (Rituximab: 375mg/m2 weekly for 4 weeks). Markedly, after the first two doses, a significant clinical improvement was noted. The tolerance of rituximab was good. Six months later, the patient reported a complete disappearance of headache and a significant regression of gait disorders.
Two years later (December 2007), there was no clinical sign of recurrence, the renal function was stable, and the brain MRI showed the persistence of hypersignals and infarction zones remnants. The thoracic CT scan showed only a single nodule (Figure 3(b)). The immunosuppressive treatment consisted of tacrolimus 1mg/d and prednisone 0.2mg/kg/d. The last thoracic and brain CT scans (February 2010) showed a complete disappearance of the pulmonary and cerebral lesions. Laboratory results revealed creatinine level 1.1mg/dL (101��mol/L), negative proteinuria, normal LDH level, and negative EBV plasmatic PCR. Immunophenotyping of blood lymphocytes revealed low CD19 count (10/mm3). 3. Discussion This paper highlights the diagnostic and therapeutic difficulties of LYG.
Our patient presented many risk factors of this disease including: age, immunosuppression, administration of antilymphocyte sera for her two renal transplants, and the reactivation of CMV. The clinical presentation demonstrated the heterogenecity and the abundance of the symptoms. It should be noted a clinicoradiological delay for the diagnosis of pulmonary lesions. Our therapeutic approach was sequential, initially by a reduction in the immunosuppression, then rituximab was introduced. 3.1. Frequency LYG is a rare disorder belonging to the group of type B lymphoproliferative diseases. It affects males > females (2 men for 1 woman) and affects primarily immunocompromised patients. The peaks of frequency concern 3rd and 6th decades [5, 6].
Patients presenting LYG have 10 to 60% risk to develop large B cells lymphoma. LYG is a serious disorder with a median survival of 2 years in the general population. The main cause Brefeldin_A of death is the progression of pulmonary lesions [7]. In renal transplantation, the literature reported 6 cases among which 3 cases were diagnosed postmortem and 3 other cases with good outcome (one case after a reduction in immunosuppression, 2 cases after chemotherapy) [1, 2, 8�C11]. 3.2.
Only a tortuous interosseous artery supplied the amputation site
Only a tortuous interosseous artery supplied the amputation site. (b) Venography showed complete … 3.3. Postsurgical Follow-Up 3.3.1. Musculoskeletal Postoperative Surveillance Immediate postsurgical radiographs showed satisfactory osseous and hardware alignment in all patients. Follow-up radiographs obtained at 1, 3, 6, 9, and 12 months showed progressive osseous Dasatinib FDA healing, maintained alignment, and diminishing soft tissue swelling (Figures 4(a) and 4(b)). Two patients developed postsurgical hematomas, one of which was detected on CT and confirmed by ultrasound, as CT evaluation was significantly degraded by artifact from surgical hardware (Figure 5). Follow-up imaging Inhibitors,Modulators,Libraries at 6 months and 1 year documented one episode of delayed-union that progressed to nonunion with failed hardware, prompting resection of the distal ulna and removal of the fractured fixation plate (Figure 6).
Figure 4 (a) Immediate postsurgical radiograph shows anatomic Inhibitors,Modulators,Libraries bony alignment and hardware with extensive soft tissue swelling. (b) One-year follow-up showing decreased swelling and interval osseous healing. Figure 5 Postsurgical hematoma, questioned on CT and confirmed by ultrasound, as CT evaluation was significantly degraded by artifact from surgical hardware. Figure 6 Radiograph showing development of nonunion and failed hardware. 3.3.2. Vascular Postoperative Surveillance All five patients presented for routine surveillance with peripheral in-office ultrasound that was performed by the clinical service to check for signs of stenosis from endothelial proliferation as evidence of rejection.
Postoperative angiography was performed at one year to reevaluate the vascular anastomoses. On CT angiography, one patient showed mild vascular narrowing at the anastomotic site without progressive narrowing on subsequent imaging. Given the stability, this was attributed to focal postoperative Inhibitors,Modulators,Libraries scarring rather than rejection. None of the patients progressed to the point of showing signs of rejection detectable by imaging, even when rejection was Inhibitors,Modulators,Libraries noticed clinically by skin biopsy. All transplants remained viable at the time of this submission with the exception of one patient who required explantationfollowing immunosuppression noncompliance. At the time of transplant removal, intraoperative angiography demonstrated patent vasculature.
This was confirmed by peripheral sonography (12MHz) at the level of the vascular Inhibitors,Modulators,Libraries anastomosis with normal velocities. However, due to the degree of skin thickening and edema, extensive beam attenuation limited the utility of ultrasound interrogation of the digital arteries. 4. Discussion Extremity allotransplantation is immensely complex surgically, medically, and psychologically, necessitating life-long Drug_discovery immunosuppression and compliance with intense physical rehabilitation.
Altogether, 19 split-liver
Altogether, 19 split-liver either transplantation were included. The local ethic committee approved the study. Written informed consent was obtained from all patients before blood was taken for DNA analysis. 3. Definition Inhibitors,Modulators,Libraries of ITBL ITBL was defined as nonanastomotic intra- or extrahepatic biliary strictures without any history of hepatic artery complications, ABO, incompatibility or other known causes of bile duct damages. In all cases patency of the hepatic artery was proved by Doppler ultrasound, computer tomography based angiography or conventional angiography. Recurrence of primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC) and vanishing bile duct syndrome were ruled out in all cases by liver biopsy. Diagnosis of ITBL was always established with endoscopic retrograde cholangiography or percutaneous transhepatic cholangiography.
4. Genotype Analysis All genotype analyses were performed at the Johannes Gutenberg University of Mainz, Department of Transplantation Surgery. For analysis of the CCR-5 genotype, genomic DNA was prepared from 200 ��L peripheral Inhibitors,Modulators,Libraries blood using the QIAamp DNA blood kit (Qiagen, Cologne, Germany). 2.5 ��L of DNA were amplified by PCR using the following CCR-5 specific primers: CCR-sense, 5��-CAAAAAGAAGGTCTTCATTACACC-3�� and CCR-5-antisense, 5��-CCTGTGCCTCTTCTTCTCATTTCG-3��. The PCR mixture was composed of 2.5 ��L 10 x PCR buffer (Roche Molecular Systems, Mannheim, Germany), 0.5 ��L of 12.5 mmol/L dNTP (PeqLab, Erlangen, Germany), 2.5 ��L Inhibitors,Modulators,Libraries of each sense and antisense primer (10 ��mol/L), and 1.
25 U AmpliTag DNA polymerase (Roche Molecular Systems) Inhibitors,Modulators,Libraries in a total volume of 25 ��L. Forty PCR cycles were run on a Genius thermocycler (Techne, Cambridge, UK), using the following temperature profile: initial denaturation, 94��C 3 minutes; amplification, 94��C Inhibitors,Modulators,Libraries 1 minute, 64��C 1 minute, and, 72��C 1 minute (40 cycles); terminal elongation, 72��C 9 minutes. The size of the wild-type product was 189 base pairs (bp), and the CCR-5��32 allele yielded a product of 157 bp. PCR products were analyzed by 2% agarose gel electrophoresis. 5. Statistical Analysis All statistical calculations were performed in SPSS 11.3 (SPSS Inc., Chicago, USA). Data are given as mean values �� standard deviation. Descriptive statistics were used to summarize the donor and recipients characteristics. For independent variables, cross tabulations and chi-square tests were performed. Nonparametric Dacomitinib variables were evaluated with Fisher's exact test, and asymptotic significance was calculated. All of the tests performed were two-sided. P-values of P < .05 were considered as statistically significant. All calculations were performed in association with the Department of Biometrical Medicine of the Humboldt University of Berlin. 6. Results 6.1.

redpajama_set_name: RedPajamaCommonCrawl


Imagine a fairy-tale nature of the dark forest in the mountains, tall trees and clouds that stuck in the trees, impassable trails, torrents of mountain rivers, steep slopes and ... a cave.
The picturesque valley of Hachahbyur river to the west from Ijevan, Armenia, called Lastiver, is amazing in its beauty. Lastiver is not just a cave in the valley of Hachahbyur River, but also an area surrounded with forest, river and waterfalls.
The name of this cave is translated from Armenian as "up the raft." Why such an unusual name?
There is a common explanation. The cave is located on the slope of a very steep gorge. The villagers of the Yenokavan village had to build a log ladder to be able to get to the gorge, which is located three kilometers from the river Hachahbyur. The staircase was like a kind of a vertical raft, on which people went up and down in the gorge. So the name of this place became popularly known as Lastiver - "up the raft."
The peculiar terrain, waterfalls, green forests make Lastiver a favorite tourist destination. Surely, only the lazy did not happen here. It is noteworthy that Lastiver remains a popular destination for many years.
Lastiver causes interest among archaeologists and historians, as well as local residents and tourists.
Lastiver is in the autumn, when the forests are full of all sorts of colors - from bright green to burgundy red.
Noteworthy is also the history of the caves. There is a belief that in XIII-XIV centuries in these caves local people hid from invaders. After a close examination of the drawings on the rocks of the cave, you can see the entire scenes from their life. Lastiver leaves a deep lifetime impression from a trip to Armenia. Its beautiful nature - caves, gorges, forests, waterfalls, and, of course, rocks, rocks and rocks again will never leave you indifferent.


text:
'use strict';

require('../common');
const { strictEqual } = require('assert');
const { isatty } = require('tty');

strictEqual(isatty(0), true, 'stdin reported to not be a tty, but it is');
strictEqual(isatty(1), true, 'stdout reported to not be a tty, but it is');
strictEqual(isatty(2), true, 'stderr reported to not be a tty, but it is');

strictEqual(isatty(-1), false, '-1 reported to be a tty, but it is not');
strictEqual(isatty(55555), false, '55555 reported to be a tty, but it is not');
strictEqual(isatty(1.1), false, '1.1 reported to be a tty, but it is not');
strictEqual(isatty('1'), false, '\'1\' reported to be a tty, but it is not');
strictEqual(isatty({}), false, '{} reported to be a tty, but it is not');
strictEqual(isatty(() => {}), false,
            '() => {} reported to be a tty, but it is not');

redpajama_set_name: RedPajamaGithub


A few unusual paragraphs in the minutes from the May FOMC meeting have caught the attention of market participants. It has raised some bigger questions about the length of time over which the Fed will be shrinking their balance sheet and their plans for the future operation of US monetary policy.
The FOMC currently sets a target band for the overnight rate for uncollateralised lending between banks, the fed funds rate, and also sets the interest rate that they pay on excess reserves, the IOER. The IOER is currently set to be equal to the upper end of the target band. Since the beginning of the year, the federal (fed) funds rate has steadily risen towards the top of its target range. In response, the FOMC minutes reveal they are likely to adjust down the interest rate they pay on excess reserves (the IOER), relative to the top of the target range, by five basis points to be more confident of keeping the fed funds rate within the target range.
Source: Thomson Reuters, Fidelity International, June 2018.
The main driver of the move higher in the fed funds rate has been increased T Bill issuance by the treasury, which has driven up bill yields and pushed up short term rates as well. However, the bigger worry for the Fed is that some of the upward pressure on money market rates has been due to reserve scarcity. That reserve scarcity could be happening so early in the process of unwinding quantitative easing would be evidence that the natural level of reserves in the system is far higher than previously thought. It implies that they would have to taper or suspend the balance sheet reduction far earlier than projected.
The Fed's own projections include a range from $400 billion of reserves at their minimum or 'normalised' balance sheet, which would happen in 2023, to $1 trillion of reserves, which would happen in 2020. (1) After the balance sheet hits its minimum size, the Fed will become net buyers of Treasuries again. If the natural level of reserves is at the high end of the range, as we suggest above, it means they will become buyers sooner rather than later.
Source: Fidelity International, June 2018.
Ultimately, the recent moves have brought forward the decision of how the Fed will run monetary policy in the long run. The trade-off between the options is the degree to which the Fed can reduce the balance sheet. If they want to operate with abundant excess reserves, they will control the fed funds rate by setting IOER within the target range. This will limit the extent to which they can reduce the balance sheet, and mean that they become net buyers of Treasuries sooner. If they want to operate with a scarcity of reserves, IOER will act as a floor to fed funds and the discount window as a ceiling for the target range. This will allow the Fed to run down their balance sheet for longer, but also implies scarcer reserves, lower money supply and tighter financial conditions globally.
The decision on how to run monetary policy will, in large part, come down to how determined the Fed is to significantly reduce its balance sheet.


Blue soft plastic swim ring with letters print.
Note: Not a safe saving device, and only use in shallow water under adult supervision.
Beautiful and in perfect condition!
Nice transaction and great communication ! Thank you !


CONTROLO 2016 will be the 12th conference in the successful series of conferences on automatic control sponsored by APCA, the Portuguese association of automatic control and national IFAC organization member.
This edition of the conference will be jointly organized by the School of Engineering, University of Minho, INESC-TEC and APCA and will be co-sponsored by IFAC.
The conference will be held September 14-16, 2016, at the campus of University of Minho, in Guimarães, a Portuguese world heritage city, 55 kilometers to the north of Porto.
The proceedings of the conference will be published in the Springer Lecture Notes on Electrical Engineering, indexed by ISI Proceedings, EI-Compendex, SCOPUS, MetaPress, Springerlink.
CONTROLO 2016 will provide an excellent opportunity for presenting new results and to discuss the latest research and developments in the field of automatic control.
While the topics of CONTROLO 2016 should be as wide as possible, we would like CONTROLO 2016 to become a privileged place to affirm the understated contribution of control and automation in general to human well-being. Whenever relevant, prospective authors are strongly encouraged to stress such contribution in their reported research and technology developments, so that a coherent overall picture can emerge from the conference and this gains a distinctive character.
– The welcome reception that will be held at archaeological Museu Martins Sarmento and will be preceded by a visit to the historic center of Guimarães.
– The gala dinner that will be held at Pousada Mosteiro de Guimarães, a 18th century monastery magnificently rehabilitated and redesigned for tourism.
Submissions should be made through the Easychair submission system until February 5, 2016. Please follow this link to enter your submission or to create an Easychair account allowing for the submission your paper.


We've seen solar-powered transit shelters, but this eco-friendly transit center with transit stops outfitted with green walls may be a first. With the help of greenscreen green walls, the City of Tempe Transit Center is seeking LEED Platinum certification. The mixed use facility, designed to be 52% more efficient than a traditional building of its kind, went with green walls to provide a buffer from the harsh Arizona sun and heat.
Manufactured by a Los Angeles-based company, greenscreen is a three-dimensional, welded wire trellising system that provides space for plants to grow and intertwine. The trellis panels can be applied in conjunction with the built environment, such as with this ASU School of Sustainability, or used in other ways. And we're seeing the product used with greater frequency.
This project will be highlighted this year at the GreenBuild Conference November 10-13. Stop by and check it out.
For further information on the Tempe Transportation Center or the LRT stations that use similar materials check out our website.
Very simple and natural way to solve a problem. Nice!
Very pretty. I would be happy to see these installed all over the area. There just is not enough green in Arizona.
Nice! I like plantsies. Well, we can also have our homes to be like plants when we use solar energy.
Nice to know that people really appreciate what we've done.
for a bus. Cool effect.
Nicely done! One piece of incorrect information: the ASU School of Sustainability did not participate in this project. The shelters were designed by Otak and Architekton, and constructed by Adolfson & Peterson.


A rare opportunity for a talented, fluent Indonesian speaking Research Executive has just become available to join a team of skilled qualitative researchers within this dynamic and growing consultancy. With 5 international offices across the globe, this consultancy develops new products services and communication for some of the most prominent brands across sectors such as Automotive, Tech, Media, Travel and Retail.
As Qualitative Research Executive, you will moderate online communities, designing research activities such as brainstorms, surveys, blogs and online workshops, whilst also engaging with the communities' members to probe consumer comments and drive valuable and strategic insight. You will conduct qualitative analysis of your findings, to then deliver clear recommendations and reports to both clients and colleagues. Offering excellent scope for career progression, this role will allow you to also develop your presentation skills, by helping lead Consultants and Directors in presentation delivery and in nurturing strong client relationships.


The Mining Sector Faces Increasing Costs. Look At Earnings. Trading Arguments Against Holding Gold Stocks. What is the trade?
4 Gold Mining Stocks Crushing the Stock Market Today. August 20, Gold mining stocks tend to move in a similar fashion to gold Research Brokers before you trade.
Trade war apprehensions due to the ongoing imbroglio between the United States and China have supported gold prices lately. However, strength in the.
While the lackluster gold price in an environment of growing uncertainty weighs on sentiment in the mining space, one junior CEO said that there is a more significant issue the sector faces in a global trade war.
Smokefoot Trade amp; Loan is the largest and the oldest Keene Engineering Gold Mining Equipment dealer on the East Coast.Our inventory includes anything from gold pans to sluice boxes to dredges. We can ship via UPS all over the United States.
Alibaba offers 16,276 gold mining plant products. About 58% of these are mineral separator, 11% are crusher, and 10% are other mining machines. A wide variety of gold mining plant options are available to you, such as sprial separator, flotation separator, and gravity separator.


text:
Q: Regex to find certain characters in a string I'm doing this in Javascript, so there might be an easier way?  However I have a string that looks like this:
designs/<random_id>/<random_id>/icon_<random_id>.png
An example of this would be:
designs/DMFSx881yveor8qolW7DUuPxWDQ2/e53BqQG2Y3wnn8uVRw8m/icon_a5898064.png
What I want to do is to check to see if this string ends with icon_<random_id>.png  If it does, do X, otherwise do nothing
I'm not very good at Regex.  I've tried ^icon\_{*}\.png$ but I'm not having a lot of joy

A: That one matches your use case :
\/icon_(\w+)\.png$

Then you can do something like :
var matches = str.match(/\/icon_(\w+)\.png$/g);

A: You can use this code to simple check is the partial exist or not :
let reg = /(icon_[\S]+\.png)$/iu;

let str = 'designs/DMFSx881yveor8qolW7DUuPxWDQ2/e53BqQG2Y3wnn8uVRw8m/icon_a5898064.png';

let check = str.match(reg);

if(Array.isArray(check) && check[0]) {
console.log('exists');
}else{
console.log('not exists');
}

A: I would think something like /(icon_[A-z0-9]+.png)$/might be what you're looking for.
var img-reg = /(icon_[A-z0-9]+.png)$/;
var url = 'designs/DMFSx8uPxWDQ2/e53BqQG2Y3wnn8uVRw8m/icon_a58598064.png';
if (img-reg.test(url)) {
    //do something because it matched.
}

icon_ + any amount of numbers or letters followed by .png and the $ represents that it has to be at the end of the string. when you use a ^ at the beginning you state that the start has to match too.

A: This regex should work for your purpose:
^.*icon\_[a-z,0-9]*\.png$

A: /icon\_[A-z0-9]{8}\.png/
tested with regex101.com. It also provides a good explanation of how the regex works.

*

*icon matches the characters icon literally (case sensitive)

*_ matches the character _ literally (case sensitive)

*Match a single character present in the list below [A-z0-9]{8}

*{8} Quantifier — Matches exactly 8 times

*A-z a single character in the range between A (index 65) and z (index 122) (case sensitive)

*0-9 a single character in the range between 0 (index 48) and 9 (index 57) (case sensitive)

*. matches the character . literally (case sensitive)

*png matches the characters png literally (case sensitive)

A: if x = 'your string'
y = x.match(/\/icon_[^/]+.png/);

if this return value to y then x string you needed

A: You can use the following regex:
designs\/[A-Za-z0-9]*\/[A-Za-z0-9]*\/icon_[A-Za-z0-9]*.png

redpajama_set_name: RedPajamaStackExchange


text:
~Author Spotlight~ Mackenzie Flohr
I'm really excited to spotlight Mackenzie Flohr on The World Was Hers for the Reading today!
Mackenzie published her debut novel, The Right of Wands in March of 2017.
What would you like your readers to know about you?
I'm a young adult fantasy author through BHC Press. My debut novel, The Rite of Wands, came out in softcover and e-book this past March, to a lot of hype and has received some amazing reviews. If you're a fan of Harry Potter and/or Doctor Who, my book may be the perfect fit for you.
What inspires you to write?
I don't really have anything per say that inspires me to write. I am inspired by actor Matt Smith when writing The Rite of Wands since my main character, Mierta McKinnon, was written specifically for him. I'll get more into that a bit later.
However, what motivates me to write is being told I won't succeed. I know that sounds odd, but I'll elaborate. Back in 2006, I was at the airport in Orlando waiting for the plane to arrive to take my Dad and I back to Cleveland, OH. I was working on a scene, which happens in a later book in the series. There was a young girl who looked about my age with her Dad sitting across from us. They asked what I was writing about, so I mentioned a little bit about it. Afterward, my Dad smiled and told them that I was writing a fantasy series, and that I would never finish it. I was shocked, embarrassed and hurt by the outburst. Even as I am recalling that moment now, it still angers me! But that's where he went wrong. Not only did I write it, not only did I finish it, I found a company to PUBLISH it!
Is there a genre you feel drawn to write or do you see yourself tackling a variety of genres in the future?
I see myself tackling a variety of genres in the future. In fact, I've already started doing that with a short story that was written in the paranormal/horror genre for an anthology coming out in October. I'm also working on the beginnings of a futuristic sci-fi series.
Can you describe your writing space?
I think it would be easier to show a picture of what it looks like!
Can you tell us a bit about your writing process?
I actually am a mix of an outliner and a discovery writer. Some of my characters, like Mierta from The Rite of Wands for example, require me to write by the seat of my pants so it keeps the writing process intriguing!
What is your go to snack when writing?
I actually don't have one. If I do get hungry, I'll just get something that's available.
Are any of your books or characters based on personal experiences or people in your life?
Yes, though it would be more of an acquaintance in this moment of time. As I mentioned above, I was inspired to write the character of Mierta McKinnon for actor, Matt Smith. You can actually read more about how that came about on my publisher's website, plus learn how you can enter to win a signed copy of my book! (Giveaway runs through the end of June 2017)
http://www.bhcpress.com/BHC_Author_Spotlights.html
Do you have a favorite character or book you have written?
Mierta McKinnon from The Rite of Wands. I can say with 100% honesty my book wouldn't have made it to the publishing stage without him.
Any hints as to what readers can expect next?
There is going to be a special hardcover edition of The Rite of Wands coming out later this month with bonus material. I'm also working on the beginnings of the audiobook to be narrated by the very talented Jake Dudman.
Tell us about your Street Team and or Reader Group and let us know how interested readers can join.
My Reader Group can be found through my publisher's website – BHC Press. I'm part of what's called ReadNow, which is their advanced reader program. There are all kinds of books and genres featured there, and the best part of it is that it's free to join!
http://www.bhcpress.com/BHC_Galley_Program_Sign_Up_And_Request.html
When not writing your own books, who do you like to read?
I do, though to be honest I don't get very much time to. I am drawn to mysteries and thrillers particularly. I love being able to get lost in a story.
Share a random fact or two that readers don't know about you.
I am an only child
I talk to myself…a lot
Celebrity Crush? I actually don't have one
Favorite Beverage? Code Red Mountain Dew
Sweet or Savory for snacks? Sweet
What type of music do you listen to? I listen to just about everything, but I really have a thing for psychedelic trance music.
Favorite tv show? Doctor Who
Do you have any pets? Yes, I have 12 cats that I am a slave to 😉
Biggest pet peeve? When people decide to just stop and chat in the middle of the aisle/hallway, and people who don't use their turn signals
Favorite vacation spot? Orlando, FL
Morning or Night person? Night
Favorite sports team? Cleveland Indians
Hobbies? Reading comic books and playing video games.
About The Right of Wands
One boy…one Rite… And a world of deadly secrets that could change the course of history—forever
And so begins the tale of Mierta McKinnon. When a horrible fate reveals itself during his Rite of Wands ceremony, he must find a way to change not only his destiny but also the land of Iverna's.
Forbidden from revealing the future he foresees to anyone, he is granted a wand and his magical powers, but still must master the realm of magic in order to save himself and those he loves.
But Mierta is not the only one with secrets…especially when it's impossible to know who to trust.
Amazon: https://t.co/ftq6hGnAee
Barnes & Noble: http://bit.ly/2neguFt
Books-A-Million: http://www.booksamillion.com/p/Rite-Wands/MacKenzie-Flohr/9781946006431?id=6822639925501
IndieBound: http://www.indiebound.org/book/9781946006431
iTunes: https://itunes.apple.com/us/book/id1212546091
Kobo: https://www.kobo.com/us/en/ebook/the-rite-of-wands
Waterstones: http://bit.ly/2ng09AK
About Mackenzie Flohr:
Mackenzie Flohr grew up in the heartland of America, chasing leprechauns and rainbows and dreaming of angels. Her parents nurtured a love of fantasy and make-believe by introducing her at a very young age to the artistic and cultural opportunities that the city of Cleveland had to offer.
From the time she could hold a pencil, Mackenzie was already creating pictorial interpretations of classic stories, and by the age of nine, she and a childhood friend were authors and reviewers of their own picture books.
While following her love of adventure, Mackenzie found a second home, the Beck Center for the Arts Children's and Teen Theater School. It was there that a world of wonder was only a script and a performance away.
Yet it wasn't until she was on a trip to Indiana, viewing a Lord of the Rings exhibit, that the innermost desire of her heart became clear to her. She wanted to write a fantasy of her own, one that could inspire imagination in others and lead them into a magical world of their own making. She hopes The Rite of Wands will do just that.
Wherever we live and wherever we come from is our individual heartland. Anything is possible and everything can happen. Pure imagination is in all of us—we only need to discover it, and sometimes story telling helps.
Connect with Mackenzie Flohr:
Facebook: http://www.facebook.com/MackenzieFlohrAuthor/
Twitter: http://www.facebook.com/MackenzieFlohr
Instagram: https://www.instagram.com/mackenzieflohr/
Goodreads: https://www.goodreads.com/mackenzieflohr
YouTube Channel: https://www.youtube.com/channel/UC_VqhKa3CP39Q7BiYROICQw
Website: http://www.mackenzieflohr.com
Mackenzie, thank you so much for taking the time to stop by and chat with me!
It's always fun to get a sneak peak into the mind of a writer as well as what they have coming our way!
Readers, make sure you drop by and visit Mackenzie at her Social Media Sites to learn more about The Right of Wands as well as her upcoming releases.
Have questions for Mackenzie Flohr, leave a comment and I'll make sure she sees it!
fantasy, Mackenzie Flohr, paranormal
~Book Reviews by Bri~ "Pennyroyal Academy" by M.A. Larson
~Cover Reveal~ "Jacked Off" by Cory Cyr
4 thoughts on "~Author Spotlight~ Mackenzie Flohr"
Lauren H. says:
Awesome spotlight!
Thank you, Lauren!
Mackenzie Flohr says:
Thank you for featuring me! Your interview was one of my favorite
It was my pleasure! Thanks for stopping by!


Download a brochure on safety tips for professional drivers.
According to the National Highway Traffic Safety Administration, in 2013, 3,154 people were killed in distraction-affected crashes and 424,000 were injured. Any death or injury as a result of distraction is one too many.
An in-cab driving study of commercial truck drivers by the Virginia Tech Transportation Institute indicated that, by far, the most dangerous distraction observed was texting. The study revealed that truck drivers who texted while driving had 23 times the risk of being involved in a crash or near-crash incident.
Operation Safe Driver aims to educate commercial vehicle drivers about the dangers distracted driving, the single largest contributing factor to traffic crashes, through its Defeat Distracted Driving program, which is directly specifically at commercial drivers and the unique distractions and challenges they face every day.
Fill out our online order form to immediately download materials, tools, files and resources for drivers.


On March 29, 1973 the last combat troops left Vietnam. More than 3 million Americans served & more than 58,000 men and women lost their lives.
From this veteran to our Vietnam veterans, thank you for your service and welcome home.


February 17, 2019, Sunday - Northeast Minneapolis Farmers Market Winter Market - Mill District Events - Minneapolis Riverfront Neighborhoods.
The Northeast Minneapolis Farmers Market invites you to the Winter Market located at Chowgirls at Solar Arts. Support local food vendors and artisans! Expect over 35 local vendors, music from The Ring Toss Twins, and children's activities! Chowgirls Killer Catering: Breakfast Sandwich, Swedish meatballs served with mashed potatoes and lingonberryand chia puddings. The bar will have local beer, bloody Mary's and mimosas!


Get off at Nagiso Station and take a bus, get off at Ogoshi bus stop, then 30 min on foot.
Day camp, hot showers, communal kitchen, water, flush toilets, rental (tents, blankets and cooking utensils), wood, lights, etc.
Temporary Closed: Reopens in late April 2017. Thank you for your patience.


Networking is proven to be successful and helps grow any business quickly and increases your sales in the most profitable way. We are now actively looking for new members who are keen to network in Mission Bay. BoB Clubs has a focus on building quality relationships over time that allow us to tap into others' networks and leverage off the opportunities that creates.
Join now or Visit our Mission Bay BoB Club as a Guest (up to twice without any obligation or pressure to join up) and learn more about how Networking through BoB Clubs can help your business.
This established business networking club in the heart of Mission Bay has members who regularly meet to network and refer business to each other.


There's no shortage of holiday parties this month, whether it's for a job, a frequented establishment or meeting up with friends for a quick holiday greeting over drinks and/or dinner. With all of the festive lights and decorations comes food and drinks a like. No need to worry. That list of New Year's resolutions will remedy all of your holiday indulgences. So, eat that extra piece of pie and be merry with a glass or two of wine this holiday weekend; for there's only a few days left to unwind.
Dinner at Bella Vista Bar and Grill. (Table decorations not provided by the restaurant but, staff assisted in setting up).
Scallops wrapped in bacon, side salad with house made dressing.
Lamb shank with gravy, mashed potatoes and vegetables. The lamb was tender and full of flavor!
Mixed berry tart. Not quite tart style, but the homestyle comfort food was tasty.
Taking a time out from the holiday rush at Crown & Anchor located in the Fairmont Hamilton Princess hotel.
Family dinner at The Waterlot Inn.
Waiting on the Bordeaux blend.
Stuffed oysters, cheese, spinach, chorizo.
NY strip dry aged with blue cheese sauce, asparagus, truffle fries, lobster mac & cheese.
Bermuda lobster stuffed with lobster mac & cheese.
The best lobster mac & cheese on the island.
House made snickers bar. Heavy on the chocolate, caramel & peanuts!


text:
StockRisers.com owner Jake Weingarten sees what Buzz is building
Author By Gabe Bock
Tweet Share Jump to Discussion
Key notes from Jake Weingarten interview
The last few months have been hectic for me. I came home from Louisville on March 1st, and I was expecting at the time to be going back to school. About two weeks later, I was packing to go back when I found out classes were put online for the rest of the semester. I'll be honest, the first thing that came to my mind was not classes, but the summer and the AAU circuit and how that would be affected by all of this. There was a lot of change very quickly.
Over the last few months, I have been able to continue building connections. Things have only gone up for me since all this began, which is weird to say. I've been putting in 20 hour days building these connections and continuing to develop Stock Risers, and it's been great to see the results.
I'm only 19 years old, but I have gotten the opportunity to write, and I've had some great experiences. Partnering with F5 Sports is everything you wish for in a business opportunity. To continue building this brand and work with some great people and connections is essential. We've been working every day and every week to get to this point.
Buzz Williams has been doing an exceptional job at Texas A&M. I got to witness his culture firsthand when I came down for practice and see what Buzz is doing. It was one of the more intense practices I have ever seen. Everyone in the program was involved in putting on the practice. It was one of the more impressive things I've seen. He is building a culture at A&M, and they have great coaches there that are set out to get the best from their players.
I've gotten a firsthand look at Hassan Diarra. I think he is one of the best guards in the class. I think he is a perfect fit for a Buzz Williams team. The future is bright for his program, and I think Jaxson Robinson getting reclassified is a big boost for that team moving forward.
Texas A&M recently had a virtual visit with Franck Kepnang. I got a chance to watch him play as well back in December. I remember John Calipari was there to see another player in the game, but he left with his eyes set on Kepnang after witnessing the performance he put on. He's a dominant player, has a high basketball IQ, and as a big man, he is not lazy by any means. I know Buzz doesn't care about the rankings. Buzz cares more about getting the right fits for his system, and Kepnang strikes me as a Buzz Williams player. He would fit very well within his scheme.
I think in ranking guys A&M has the best chance with; I would put Wade Taylor at
No. 1, Harrison Ingram at No. 2, Langston Love at No. 3, and John Camden No. 4. Camden is a new offer, and other schools are going after him much harder now, so he would be a tougher pull. I think Wade Taylor is number one because he has been actively seeking A&M. He's been on two virtual visits in back to back weeks, so he has A&M on his mind.
Harrison Ingram's connections and relationships with the other commits makes me see him as a guy I can see jumping into the fold. I think Love is a guy you want on your team as a knockdown shooter, someone who represents a big upgrade on anyone's offense. If Buzz really pursues him, and with Love being a native of Texas, he could easily end up at A&M. Whoever Buzz lands, he will be adding him to a class and a program that is looking to build a championship squad at A&M, and he's off to a great start.
You can check out more of Jake's work at StockRisers.com
Never miss the latest news from TexAgs!
Join our free email list
Story Poster story photo
End-of-half scoring contributions played big role in Texas A&M's 2020 success
by Olin Buchanan
Story Poster
story photo
Highlights: Top 2022 QBs Klubnik, Ewers battle for 6A Division I crown
by Jason Howell
Texas A&M basketball's Wednesday night contest at Vanderbilt postponed
by Dalton Hughes
2021 A&M signee Shemar Turner named DFW defensive lineman of the year
Tom Hart discusses what's next on Rocky Top following Pruitt's ouster
by Gabe Bock
Tags: Harrison Ingram, Langston Love, Wade Taylor, Hassan Diarra, Jaxson Robinson, John Camden
Public Service Forums
Coronavirus/COVID-19 News & Information
Billy Liucci's TexAgs Premium The Premium Pub Aggies Only Varsity Texas A&M Football Texas A&M Men's Basketball Texas A&M Women's Basketball Texas A&M Baseball & Softball Texas A&M Soccer SEC Country Old Rivalries NFL & Fantasy Football NBA & Other Basketball MLB & Other Baseball Recruiting Outdoors Golf Other Sports Ticket Exchange
Five Star General General The Student Section Job Network Entertainment Food & Spirits Bonfire Religion & Philosophy Politics Business & Investing Real Estate Academics Automotive The Nerdery Health & Fitness Military History Classifieds Travel Home Improvement
Aggie Network Forums
Aggieland Austin San Antonio Metroplex Houston Central Texas Panhandle / South Plains West Texas South Texas East Texas Gulf Coast Around the Nation Across the Globe
Discussion from...
Billy Liucci's TexAgs Premium (26 replies) Texas A&M Men's Basketball (0 replies) Recruiting (0 replies)
2,023 Views | 0 Replies | Last: 8 mo ago by Gabe Bock
There are not any replies to this post yet.
Skip to Last Page 1
Post Reply Back to topics
This post has been flagged.
Click to display linked image.


At your nearest Tires Plus, you'll receive top-quality tires, maintenance, and repair services to help keep your car running smoothly. Find coupons and offers, schedule an appointment, or come see us at your closest 52746-area location.
When you depend on Tires Plus near the 52746 area you'll get reliable vehicle repair and maintenance services. Locate a Tires Plus location near you, or book your next appointment online or by phone.
At Tires Plus, we go above and beyond customer satisfaction. We believe in providing our guests with the best in tires, services, and expert car care. We're also committed to helping you save money. That's why we have coupons and deals on both tires and services. Drop by your nearest 52746-area Tires Plus store or pre-book an appointment now!
At Tires Plus, we put the Plus into all we do. That's why we offer so much more than tires. Whether your car or truck needs a routine inspection or you need a problem checked out, count on Tires Plus in the 52746-area to keep your vehicle running smoothly.


Queen duvet cover (88" x 88") featuring the image "The Godfather" by Dale Loos Jr. Our soft microfiber duvet covers are hand sewn and include a hidden zipper for easy washing and assembly. Your selected image is printed on the top surface with a soft white surface underneath. All duvet covers are machine washable with cold water and a mild detergent.
Dale, Congrats on your work and sale!
The second painting done for "Villains?" inspired by Don Vito Corleone, The Godfather. A character who embodies the principles of respect, and savage commitment to family.


text:
function iPhoneMapInfoWindow(events, map, iPhoneMapPages, iPhoneAircraftDetail)
{
    var that = this;
    var mEvents = events;
    var mMap = map;
    var mInfoWindow = null;
    var mOnDisplay = false;
    var mDisplayNode;
    var mElements = {};
    var mTrackingAircraft = null;
    var mIPhoneMapPages = iPhoneMapPages;
    var mIPhoneAircraftDetail = iPhoneAircraftDetail;

    this.initialise = function()
    {
        createDisplayNode();
        mInfoWindow = new google.maps.InfoWindow({
            content: ''
        });

        mEvents.addListener(EventId.noLongerTracked, noLongerTrackedHandler);
        mEvents.addListener(EventId.acListRefreshed, aircraftRefreshedHandler);
        mEvents.addListener(EventId.iPhonePageSwitched, iPhonePageSwitchedHandler);
    };

    this.displayAircraftInformation = function(aircraft)
    {
        that.hide();
        if(aircraft.Marker !== undefined && aircraft.Marker !== null) {
            fillDisplayNode(aircraft);
            mInfoWindow.setContent(mDisplayNode);
            that.show(aircraft.Marker.getAnchor());
            mTrackingAircraft = aircraft;
        }
    };

    this.show = function(anchor)
    {
        if(!mOnDisplay) {
            mInfoWindow.open(map, anchor);
            mOnDisplay = true;
        }
    };

    this.hide = function()
    {
        if(mOnDisplay) {
            mInfoWindow.close();
            mOnDisplay = false;
        }
    };

    function aircraftRefreshedHandler(sender, args)
    {
        if(mTrackingAircraft !== null && mIPhoneMapPages.getSelectedPageId() === PageId.map) {
            updateDisplayNode(mTrackingAircraft);
        }
    };

    function iPhonePageSwitchedHandler(sender, args)
    {
        if(mTrackingAircraft !== null && mIPhoneMapPages.getSelectedPageId() !== PageId.map) {
            that.hide();
            mTrackingAircraft = null;
        }
    }

    function noLongerTrackedHandler(sender, aircraftList)
    {
        if(mTrackingAircraft !== null) {
            var length = aircraftList.length;
            for(var i = 0;i < length;++i) {
                if(mTrackingAircraft === aircraftList[i]) {
                    that.hide();
                    mTrackingAircraft = null;
                    break;
                }
            }
        }
    };

    function linkClickedHandler()
    {
        if(mTrackingAircraft !== null && mIPhoneAircraftDetail !== undefined) {
            mIPhoneAircraftDetail.setAircraft(mTrackingAircraft);
            mIPhoneMapPages.select(PageId.aircraftDetail, PageAnimation.none);
        }
    };

    function createDisplayNode()
    {
        mDisplayNode = createElement('div', 'infoWindow', null);

        var group = createElement('ul', 'infoWindowGroup', mDisplayNode);
        createItemNode(group, null, 'OpFlag');
        createItemNode(group, 'ICAO', 'Icao');
        createItemNode(group, 'Reg', 'Reg');
        createItemNode(group, null, 'RegType');
        createItemNode(group, 'Operator', 'Op');
        createItemNode(group, 'Type', 'Type');
        createItemNode(group, 'Model', 'Mdl');
        createItemNode(group, 'Callsign', 'Call');
        createItemNode(group, 'From', 'From');
        createItemNode(group, 'Via', 'Via');
        createItemNode(group, 'To', 'To');
        createItemNode(group, 'Altitude', 'Alt');
        createItemNode(group, 'Speed', 'Spd');

        var link = createElement('div', 'infoWindowLink', mDisplayNode);
        link.onclick = linkClickedHandler;
        link.innerHTML = "Aircraft information";
    };

    function createItemNode(parent, labelText, idSuffix)
    {
        var top = createElement('li', 'infoWindowItem infoWindowHidden', parent, 'infoWindowLine' + idSuffix);
        var label = createElement('div', 'infoWindowLabel', top);
        if(labelText !== null) label.innerHTML = labelText + ':';
        var value = createElement('div', 'infoWindowValue', top, 'infoWindowValue' + idSuffix);

        mElements[idSuffix + 'Line'] = top;
        mElements[idSuffix + 'Value'] = value;
    };

    function setItemNode(idSuffix, isVisible, content)
    {
        var lineElement = mElements[idSuffix + 'Line'];
        var valueElement = mElements[idSuffix + 'Value'];

        setClass(lineElement, isVisible ? 'infoWindowItem' : 'infoWindowItem infoWindowHidden');
        if(isVisible) valueElement.innerHTML = content;
    };

    function fillDisplayNode(aircraft)      { fillDisplayNodes(aircraft, true); };
    function fillDisplayNodes(aircraft, forceSet)
    {
        var roomToBreathe = window.innerHeight >= 600;

        if(forceSet || aircraft.OpIcaoChanged)  setItemNode('OpFlag', roomToBreathe && aircraft.OpIcao !== '', aircraft.formatOperatorFlag());
        if(forceSet || aircraft.IcaoChanged)    setItemNode('Icao', roomToBreathe && aircraft.Icao !== '', aircraft.Icao);
        if(forceSet || aircraft.RegChanged)     setItemNode('Reg', roomToBreathe && aircraft.Reg !== '', aircraft.Reg);
        if(forceSet || aircraft.OpChanged)      setItemNode('Op', aircraft.Op !== '', aircraft.Op);
        if(forceSet || aircraft.TypeChanged)    setItemNode('Type', roomToBreathe && aircraft.Type !== '', aircraft.Type);
        if(forceSet || aircraft.MdlChanged)     setItemNode('Mdl', roomToBreathe && aircraft.Mdl !== '', aircraft.Mdl);
        if(forceSet || aircraft.CallChanged)    setItemNode('Call', aircraft.Call !== '', aircraft.Call);
        if(forceSet || aircraft.FromChanged)    setItemNode('From', aircraft.From !== '', aircraft.From);
        if(forceSet || aircraft.ToChanged)      setItemNode('To', aircraft.To !== '', aircraft.To);
        if(forceSet || aircraft.StopsChanged)   setItemNode('Via', aircraft.Stops.length > 0, formatStops(aircraft.Stops));
        if(forceSet || aircraft.AltChanged)     setItemNode('Alt', aircraft.Alt !== null, aircraft.formatConvertedAlt());
        if(forceSet || aircraft.SpdChanged)     setItemNode('Spd', roomToBreathe && aircraft.Spd !== null, aircraft.formatConvertedSpd());

        if(forceSet || aircraft.RegChanged || aircraft.TypeChanged) setItemNode('RegType', !roomToBreathe && (aircraft.Reg !== '' || aircraft.Type !== ''), aircraft.Type + ' ' + aircraft.Reg);
    };
    function updateDisplayNode(aircraft)
    {
        var oldHeight = mDisplayNode.offsetHeight;
        fillDisplayNodes(aircraft, false);
        if(mDisplayNode.offsetHeight != oldHeight) {
            that.hide();
            that.show(aircraft.Marker.getAnchor());
        }
    };

    function formatStops(stops)
    {
        var result = '';
        for(var i = 0;i < stops.length;++i) {
            result += stops[i];
            if(i + 1 != stops.length) result += '<br />';
        }

        return result;
    };
}


bit.ly - We are charmed presently proficient to give Un certified Boxes bundling administrations, formally affirmed for harm merchandise transports inside the EU.
bit.ly - We are an UN Approved HDPE drums suppliers and the proficiently managed firm engaged in manufacturing and supplying of wide range of HDPE drums. Our goal is to endow our prestigious clients with 100% satisfaction.
bit.ly - Offered by them is an extensive arrangement of very strong UN certified boxes. The experts make utilization of better review fiberboard and present-day innovations than fabricating the items according to the most recent rules of the business.
You Cannot Take Chances With Packaging Of Dangerous Goods For Shipments!
alfalaahdgindia.blogspot.in - In fact, some of the dangerous goods are packed well in case of handling dangerous goods. However, our packaging's services are the top notch in handle the dangerous goods packing services for every customer.
alfalaahdgindia.blogspot.in - The packaging of dangerous or hazardous products requires immense care, which has enabled companies to acquire UN Certification.
Our company offers professional team who has dedicated to pack and carry out with the number of the Hazards goods packing with the support of the UN packaging.


text:
Q: How does wiring two LNAs in parallel affect charactaristic impedance? It appears that wiring amplifiers in parallel improves the signal to noise ratio.  I thought I would experiment with two SAV-541+ LNAs in parallel and see how they perform:

*

*How does wiring an LNA in parallel affect the impedance on both sides?

*Will it cut it in half and create 25-Ohm impedance values?

*If so, will it be 25-Ohms on both sides, or just one or the other?

-Eric, KJ7LNW

A:
How does wiring an LNA in parallel affect the impedance on both sides?

I know that with "wiring" you mean "connecting", but the link you add is a device that works at 45 MHz to 6 GHz. You don't model that as wires carrying current: You transport waves in waveguides. Seeing this package:

it's SMD, so this was designed for a PCB with microstrip transmission lines :)

Will it cut it in half and create 25-Ohm impedance values?

So, since you can't physically put them in the same position, the point where the impedance change happens is where you split that transmission line to go to both amplifiers, and the point where you combine the two transmission lines coming out of them.
These points actually have to be considered components with their own properties. We call them "power dividers" (or "power splitters") and "power combiner", respectively.
That power divider can be designed to e.g. have the same 50Ω input impedance as the two outputs. Also, it might be very interesting to not have power that reflected back from one of the amplifiers for any reason end up in the other (because that would be a great way of building a Gigahertz oscillator that you can not control).
Same goes for the power combiner at the output: you can make the output impedance be half or same as the input input impedance, by choosing an appropriate design for it!
In fact, the datasheet does say this:

• External biasing and matching required

So, your job is to first match the input impedance of the amplifiers to the transmission line coming e.g. from your antenna!
It might be easiest to do something like:

*

*Have \$x\$ Ω wave impedance on your antenna trace. Want \$y\$ Ω wave impedance at the combined output (\$x\$ and \$y\$ can be the same, but don't have to be. For example \$x=75\$ and \$y=50\$ would be usual choices!)

*match both amplifiers to \$\sqrt 2x\$ Ω impedance

*Use a lossless power divider that converts the single \$x\$ Ω transmission line to two \$\sqrt2x\$ Ω transmission lines going to your amplifiers.

*Match your amplifier's outputs to \$\sqrt y\$ Ω.

*Combine with the same architecture as used as splitter above, but adjusted to output impedance of \$y\$ Ω and thus input impedance of \$\sqrt 2y\$ Ω.

It appears that wiring amplifiers in parallel improves the signal to noise ratio.

Generally, um, I'd be careful with that. The article you refer to doesn't apply to these RF LNAs, but to opamps on non-RF frequencies.
If you length match well enough and your amplifying devices really have the same phase (which can change with but a gust of warm air), then yes, combining the output of two amplifiers will lead to twice the signal power on the combiner's output, which is the presumption of the formulas given in that article. Sadly, that's hard, and often, you'll just cancel out some power of one amplifier by not phase-adjustedly the other.
If you want a better noise figure in an LNA, get an LNA with higher gain and the same low noise figure, or one with a lower noise figure and the same gain. LNAs tend to internall by really really simple devices - when you look at that datasheet, they even tell you it's but a single FET in a package. Why? Because, in general, every semiconductor junction you use to generate an output signal introduces more noise.
So, receiver system design is usually taking an LNA with a good noise figure and at least OK gain, and then cascading, not paralleling, more amplifiers if you need more power. I think wikipedia's Friis formula for noise article will come as a big enlightenment!
(by the way, the noise figure of this LNA is really quite excellent. Check thrice whether this is really the limiting source of noise in your whole transmitter-receiver signal chain before trying to optimize it. As always: requirements first, design later!)


text:
Dies ist eine Liste der Städte in Ecuador mit mehr als 30.000 Einwohnern nach Ergebnissen der Volkszählungen (Zensus) vom 28. November 1982, 25. November 1990, 25. November 2001 und 28. November 2010.

Die beiden mit Abstand größten Agglomerationen in Ecuador sind Guayaquil mit einer Einwohnerzahl von 3.295.143 und die Hauptstadt Quito mit einer Bevölkerung von 1.941.506 (Stand jeweils 1. Januar 2005). Damit konzentrieren sich 43 Prozent der Menschen des Landes in beiden Regionen.

Die Einwohnerzahlen beziehen sich auf die jeweilige städtische Siedlung im engeren Sinne – dem geografischen Stadtgebiet – nicht auf die Stadt oder Gemeinde im politischen Sinne.

Siehe auch
Liste der Städtelisten nach Ländern

Weblinks
Instituto Nacional de Estadísticas y Censos de Ecuador
City Population - Historische Einwohnerzahlen der Städte Ecuadors

Ecuador

redpajama_set_name: RedPajamaWikipedia


A large spacious room complete with stage and built in state-of-the-art sound system.
This room is ideal for up to 300 guests seated in theatre style and is equipped with comfortable seating, hearing aid loop, data projector and screen.
Benefiting from natural daylight, the Main Hall is suitable for conferences, parties, weddings and live performances. Additionally, the room can accommodate a range of bouncy castles, activities and soft play making it an ideal venue for children's parties.
Please note, this room is currently available for hire on Saturdays only.


text:
The Kings' Crusade
Free DLC Released for Lionheart: Kings' Crusade
First week purchasers receive new Allies bonus content.
By IGN Staff
Updated: 5 May 2012 4:09 am
Posted: 11 Oct 2010 4:27 pm
NEW YORK - Neocore Games and Paradox Interactive today announced the release of an free DLC pack for all gamers that purchased Lionheart Kings' Crusade during the first week and ongoing until the 17th of October. The special New Allies DLC is available now on all leading digital distribution platforms.
From the development team that created King Arthur and Crusaders: Thy Kingdom Come, this real-time strategy game places you in the era of the Third Crusade, spanning the years 1189-1192. Choose your historically accurate heroes and units or choose to add mythical characters and units to enhance and diversify your Lionheart Kings' Crusade gameplay experience.
Read the full description of the free New Allies DLC pack here:
https://www.lionheartthegame.com/Game%20Info/DLC
You can add Taqi al-Din Umar, one of the trusted allies of Saladin that has been fighting alongside his vizier since they first moved to reclaim the Saracen lands. Or choose Arthur of Brittany that fought so bravely in the battle for Cyprus that he earned frequent comparisons with his legendary namesake.
Or you can bend the rules of history by adding Joan d'Arc, the enigmatic warrior-woman from another time and place and she will appeared in Jerusalem in a flash of blinding light claiming that God had brought her to free the Holy Land. At your disposal is also Lancelot, King Arthur's greatest champion, the most famous – and infamous – knight of the Round Table to the Crusader regime as you rewrite history.
Lionheart: Kings' Crusade is published worldwide by Paradox Interactive. The PC title is available for digital download on all leading digital distribution platforms and in retail stores.
Web page: www.lionheartthegame.com
Facebook: www.facebook.com/LionheartGame
Twitter: https://twitter.com/Lionheartgame
About Neocore Games
Founded in 2008, Neocore Games aims to develop high quality products. Developers of Crusaders: Thy Kingdom Come and King Arthur: The Role-PlayingWargame, Neocore Games utilizes its Coretech 3D engine to offer stable and strong technology to deliver the best in-game graphics of the industry. For more on Neocore Games, visit www.neocoregames.com
About Paradox Interactive
Since 1999, Paradox Interactive has been a leading global developer and publisher of PC-based strategy games. World-renowned for its strategy catalog, the company holds a particularly strong presence in the United States and Europe. Its steadily-growing portfolio includes originally developed titles such as the critically acclaimed Europa Universalis, Victoria and the Hearts of Iron franchises, as well as publishing titles such as the Elven Legacy series, Mount&Blade, East India Company and Majesty 2. Paradox made an explosive entry onto consoles during 2010 with the release of Lead and Gold: Gangs of the Wild West. For more information, please visit www.paradoxplaza.com and follow https://twitter.com/PdxInteractive
DeveloperNeocore Games
PublisherParadox Interactive
Release DateNovember 27, 2010
PlatformsPC
IGN's Top 10 Free-To-Play Games on Steam


It's the time of the year when you hear your feet touch the ground.
Deep frost is in there and not a live seed to be seen.
There are snow drops, what a wonderful sight.
Almost all is asleep for those shortest of days and those cold winter nights.
You take a deep breath and the air exhaled turns to steam.
Your breath shortens but so does your step, not likely to run or break into a sweat.
No, it's that time of year for a safe steady stride.
The moon seems to hang around for most of the time, is he also admiring those moments with us?
Winters are long whilst summers seem short.
So walk in the world whenever you can, because life is refreshing however we plan.
Breathe in breathe out, for living is what life's really about.


It is hard to believe I am sitting writing this article for the January magazine already! I have been here in London 3 months already-and I am finding it difficult to believe where the time has gone. The last week, I must confess, has not been a barrel of laughs: I spent it in bed suffering with bronchitis. I went off to the doctor in Denbigh Street on Tuesday with the worst hacking cough I've ever had.


text:
on map to the list
«Catherine the Great in Russia and Beyond» exhibition of arts
Saint Michael's (Engineer's) Castle
28 May, Monday
Reviews()
The exhibition offers a perspective on how Russian internal and geopolitical transformations, in which Empress Catherine II played a major part, were reflected in art of the late 18th century
The second half of the 18th century in the Russian Empire was marked by significant transformations of the social structure, legislative framework, industry, and culture. Among the major milestones of that period were growth and development of national manufactories, the foundation of the Smolny Institute and Moscow Foundling Home, and the formulation of a new charter of the Academy of Arts.
Battle pieces and allegorical paintings, drawings and engravings reflect the major war events of the epoch: the Russo-Turkish wars of the 1768‒1774 and 1788‒1790, and the Russo-Swedish war of the 1788‒1790. It was in these wars that military leadership talent of such prominent Russian commanders as A. V. Suvorov and P. A. Rumyantsev manifested itself. In 1783, the Crimea peninsula became, as Catherine herself put it, an eternal part of Russia. The artworks of the period also represent some of the Empress's projects, such as the so-called Greek project, the relationships with the Order of Malta and so on, as well as her travels across the southern governorates. Historical, cultural, and artistic connections between Russia and Western Europe were active and diverse then — among them Catherine's contacts with the prominent French intellectuals, Diderot and Voltaire.
The rich and diverse exhibition provides insight into significant events in the history of Russia by bringing together over 500 works of fine and applied arts: paintings, graphic works, sculpture, glassware and china, costumes, and more. The exhibition also features archival documents.
The exhibition includes portraits of Catherine the Great and her contemporaries by Ivan Argunov, Dmitry Levitsky, Fyodor Rokotov, Stefano Torelli, Johann Baptiste Lampi, Joseph Kreuzinger, Salvatore Tonci, and others. Moreover, visitors will see sculptural portraits by a prominent master of Russian classicism Fyodor Shubin, Italian sculptor Jacopo Monaldi, and so on.
Landscapes by Mikhail Ivanov and Fyodor Alekseev invite one to follow the Empress on her journeys across Russia, especially the Crimea. Mikhail Ivanov is renowned for his battle scenes painted in watercolour and gouache, also present in the exhibition. Furthermore, one will see works by Jacob Philipp Hackert who was commissioned by the Russian court to capture naval battles of Chesma.
The exhibition brings together objects held in the Russian Museum, State Historical Museum, Pushkin Museum of Fine Arts, Tretyakov Gallery, Hermitage, Moscow Kremlin, Pavlovsk and Peterhof Museum Reserves, Suvorov Memorial Museum and many other museums, archives, and private collections.
15 February - 28 may, 2018
Address: St. Petersburg, ul. Sadovaya, 2
Phone Number: 595-42-48
Site: http://rusmuseum.ru/
Email: info@rusmuseum.ru
To leave a review you need to authorize first
Administrator of visit-petersburg.ru
1 December 2020 - 31 December 2022
The St. Petersburg Toy's Museum
30 September 2021 - 13 March 2022
The Russian Museum of Ethnography
29 October 2021 - 1 March 2022


Last month, Mel and Dee Bixley went to The Gambia and visited many of the African Oyster Trust's projects. The following blog post is Part II of a series of articles based on extracts from Dee's diary. You can read the background to their involvement with the Trust, plus the first extract from the diaries, here.
At 10am we begin our journey up country. Our final destination tomorrow will be Jappineh Health Centre, the home of the ambulance. We collect Fanding en route and he and Kira debate whether this will be a goat, cow or donkey day.
In fact, the leisureliness with which all these creatures wander into the road makes it a 'mixed' day. Driving in Gambia has many challenges. Most of the unmade local roads have huge potholes to negotiate. And where sand has accumulated, the need to accelerate and go with the 'skid' is imperative if you don't want to get stuck. Once we understand that Kira knows exactly what she's doing, we relax!
As to Gambia's major roads, there are regular check points where you must stop for the police, military or immigration authorities. However, as soon as they realise its Kira, their stern attitudes soften and they salute with alacrity. The fact that a gun is pointing at us from a camouflaged hut nearby doesn't matter - Kira has clearly earned their respect and affection.A visit to The Big Tree Nursery received an ecstatic welcome for Kira and Fanding!
We arrive at Moses Guest House in Soma, the best place to stay near Jappineh.
Moses is a small establishment, five or six rooms situated around a courtyard, where we drink tea from pint mugs. Kira must read something in my face - "How's your comfort zone, Dee?!" she teases. She is right to do so.
After all, we have a flush loo, a tap in the wall for cleaning our teeth, and Kira has thoughtfully supplied a travel kit of essentials.
What's more, our host has been out and purchased toilet paper for us. When people are this keen to please - to hell with my OCD tendencies!


Following Pavements, their previous single from a few weeks back, the consistently on the rise dreampop duo, Wy, announce their upcoming album and reveal its moody title track. Softie comes out on April 30th, 2019 via Hybris and Beatnik.
"Being really down makes me a jerk to people," says singer, Ebba. "But if I'm being a jerk to you that probably means I love you very much. It's very complicated."
With its title reflecting on the vulnerability and the fragility which can be found all over Ebba and Michel's songwriting, Softie sounds firm, full of emotion and tenaciously performed, like an unyielding personal statement which embraces life's frailty. The song is written from Ebba's experience of being bipolar.
Ebba further explains: "Softie is an attempt at proving there is more than one way of being a functioning human being. The album is about coping, growing out of your fears, learning how to distance yourself from your anxieties and the ups and downs that comes with being bipolar. Softie is ultimately about releasing the pressure from yourself and that's what we have been doing in the process of writing these songs. We ended up with a record that was turbulent, back and forth and non-conforming. And we love that, because it feels very 'us' and we really wanted our second album to hit you in the face rather than rock you to sleep."


text:
Same Hospital And Insurer, But The Bill For His Second Jaw Procedure Was $24,000 More
Many Kids Have Missed Routine Vaccines, Worrying Doctors As School Starts
POPULAR NOW ON KPCC
Anaheim dental clinic cleared to use its water again
Courtesy NBC 4
Paul Glickman | November 8, 2016
Orange County's health officer Tuesday gave an Anaheim dental clinic the all-clear to resume use of its on-site water system to treat patients. Children's Dental Group of Anaheim replaced its system after more than 50 kids got infections following partial root canals.
Health Officer Dr. Eric Handler ordered the clinic to stop using its water on Sept. 15, after determining that it appeared to be linked to the bacterial infections. The affected children had the root canals, known as pulpotomies, between March 1 and Aug. 11, according to the Orange County Health Care Agency.
Children's Dental subsequently replaced its water system, tested the new system to ensure it meets American Dental Association standards and established a plan to monitor the water, said the Health Care Agency.
The clinic also installed safeguards to prevent future contamination, including the use of "a treatment designed to prevent bacteria from adhering to equipment as well as the installation of purification cartridges at every dental chair connected to the on-site water system," the agency said.
When dentists perform partial root canals, they remove a portion of the pulp, or the connective tissue that contains blood vessels and nerve tissue, according to the American Dental Association. Infections following the procedure can cause swelling, redness and pain around the infected tooth weeks or months afterwards.
Children's Dental Group has offices across the state, but infections have only been linked to the Anaheim location.
For more information about these infections, check out the Orange County Health Care Agency's FAQ.
Anaheim dental clinic closed due to bacteria in water
KPCC's Health coverage is a Southern California resource provided by member-supported public radio. We can't do it without you.


Be mindful in every aspect of your life.
Did you know that a simple 20 minute daily walk could instantly lower your blood pressure? Exercise can help prevent everything from diabetes, cardiovascular disease, depression and osteoporosis. We'll show you ways to fit exercise into your already busy life and have fun doing it!
What you choose to fuel your body with will determine how well it runs. Your body is a temple! It's the only one you have so treasure it. In the Warrior360Way program we recognize that everyone has a different makeup. Foods that are great for one may not work for all. Learn the right foods for YOUR body and how to create nutrient dense meals in your own home.
Do you tell yourself how AWESOME you are everyday? Are you stuck telling your self the negative stories of your past? Connecting with yourself focuses on self-care and spiritual practice. For some that may mean daily prayer/meditation, while others it may mean a yoga class or journaling may be your thing. The focus here is to engage in a practice that allows you an opportunity for reflection and introspection. To be your best for others you have to be at peace with yourself. During the Warrior360Way program we'll show you tools and resources that allow you to look inward.
Learn how to surround yourself with positive people and let go of the toxic relationships. Create meaningful relationships in all areas of your life and live a longer more fulfilled life.
Recharging your body to prevent illness or disease is paramount for maintaining a healthy lifestyle. Did you know that lack of sleep can cause weight gain? Not getting adequate rest at night may also cause you to lose your precious dreams. Learn how to balance your day and develop nightly rituals to ensure a deep, relaxing sleep!
Do you wake up in the morning feeling energized and ready to start your day of work? If you're not happy in your work environment then you could be setting yourself up for unwanted stress in your body. Constant stress that develops into chronic stress ultimately leads to inflammation in your body. It's the inflammation that eventually leads to illness/disease. Learn ways to manage the stress in your life and change your mindset about your career.


It is with great pride and excitement, that our Galavante Team would like to announce the launch of our new cookbook; The Art of International Entertaining. Before Galavante, and the extraordinary travels we've experienced since starting this adventure, my first passion was food. Yes, I lived to travel, but I traveled to eat. While working on Wall Street for most of my career, I admittedly spent my procrastination time creating elaborate dinner menus, for parties that I would host during the week at my home. Even then, I knew in my heart that my current career path, while relatively financially rewarding, was not my passion. Instead, it was the opportunity to afford the 4 course meals that I would create entirely from scratch, and the table settings, flower arrangements, candles and small party favors, which motivated me to keep my day job. It was during this time, I also started the first draft of my "Wall Street Guide to Entertaining", which now in retrospect, was the inspiration for our Food section at Galavante, and this cookbook, four years later. I've come a long way from structuring and negotiating deals in finance, and food has been a major part of my journey.
My philosophy is that food is 60% of the experience, with the other being the setting, attention to detail and most importantly, the company. In my home, I've always only entertained those who I love. From the girls night in, with the extraordinary women who inspire me, to the Sunday bachelor dinners I've been known to host, because I think everyone needs a home cooked meal, to dinners with my husband, who is both my biggest supporter and hardest critic, it's food that makes my house a home. In creating this cookbook, we wanted to bring our world experiences to you, from the over 100 countries we've visited since starting this Galavante adventure. While it's extraordinary to travel, food is a major part of a culture, which can be experienced even when you're cooling your jets at home. We wish you all the joy and adventure through our recipes, with those who mean most to you.
To purchase the cookbook, click here. If you'd like to become part of our Galavante family as a Business Class Member, we are offering a purchase one, gift one option, just for the holidays until December 24th. With the purchase of a Business Class Membership, which provides you access to our Travel Concierge, our online magazine, the Galavante cookbook and an invitation to one member event annually, you can gift a second membership gratis to the lucky individual of your choice. And of course, First Class Members receive all of those benefits, plus discounted airfare, extra perks, at least 2 VIP events annually and exclusive access at over 1700 properties worldwide. Join us.


Set in 1965, Flirting follows a free-spirited young man (Noah Taylor) who's an outcast at an Australian all-boys prep school. He meets a sophisticated South African girl (Thandie Newton) attending the school across the lake, and their interracial romance blossoms despite the intense prejudice they face. A beautiful and honest depiction of first love by director John Duigan, with outstanding performances by Taylor and Newton.


text:
Lifestyle / Motors
Volkswagen's high five
by Cheryl Livingstone
January 14, 2015, 3:15 pm Updated: January 15, 2015, 10:34 am
Sign up to our Lifestyle newsletter
Volkswagen has unveiled a new five-seater midsize SUV concept car at the North American International Auto Show in Detroit.
Called the Cross Coupé GTE, it is a plug-in hybrid with all-wheel drive, and previews Volkswagen's new US design language, combining German engineering with the American way of life.
Powering the Cross Coupé GTE is a 3.6-litre V6 petrol engine in combination with two electric motors. The six-cylinder direct-injection engine (FSI) delivers 276bhp and maximum torque of 258lb/ft, while the two electric motors deliver 40kW and 162lb/ft and 85kW and 199lb/ft (rear). They are powered by a compact lithium-ion battery housed in the centre tunnel, with energy content of 14.1kWh. The total output of the drive system is 355bhp, and using this full power, the Cross Coupé GTE, which has a top speed of 130mph, accelerates to 60mph in just 6.0 seconds.
Cross Coupé GTE
Detroit.
Police condemn 'despicable' theft from Aberdeen foodbank
Equatorial Guinea plans modular refinery move
Equatorial Guinea has expressed interest in emulating Nigeria's modular refinery initiative, led by Waltersmith Petroleum.


text:
Zalando launches exclusive capsule collection with sustainability focus
Zalando has linked up with nine Nordic brands for the spring season to "develop an exclusive, more sustainable womenswear collection" called Small steps. Big impact. by Zalando.
Zalando has launched a new sustainable collection - Zalando
The brands were selected from among the 20,000+ items flagged as sustainable from over 240 different brands on its site. The brands are Blanche, Bruuns Bazaar, Designers Remix, Filippa K, Han Kjøbenhavn, Holzweiler, House of Dagmar, Libertine Libertine and Won Hundred.
"Sustainability is an increasingly important topic in all our categories, especially in Premium," said its Director of Buying Premium, Lena-Sophie Roeper.
"We know our Premium customers demand products that have sustainability benefits. As a platform with more than 29 million active customers in 17 countries and more than 2,000 brands, we know that we can influence the demand for and the supply of sustainable fashion. That's why we're introducing our customers to sustainable fashion, working with partners who share our vision and ethics, and move the industry forward."
She added that the new collection "is a huge step in the right direction".
The company said the nine brands were challenged with a brief that called for a "cohesive, conscious collection that didn't compromise on design or quality. Less resource-intensive processing techniques, better materials and social aspects remained top-of-mind as the 70-piece collection came to life".
The materials used include organic cotton, long-lasting triacetate, and 100% recycled polyester. The brands also made use of OEKO-TEX certified prints, as well as materials that used fewer pesticides and saved more water.
The individual pieces include light, flowing dresses, structured suits, durable denim and lightweight jackets.
The firm's Director Marketing Strategy & Campaigns, Jonny Ng, said the launch "aims to increase customers' awareness of Zalando's sustainable fashion assortment, while guiding [them] towards more conscious choices. We want to demonstrate how easy it is for our customers to find sustainable styles from head-to-toe."