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Unilateral headache caused by and on the same side as cranial venous sinus stenting.
In particular, within-stent venous thrombosis has been excluded.
Over the past decade, stenting of lateral sinus stenosis has been used to treat idiopathic intracranial hypertension.
Data about 6.6.2 Headache attributed to cranial venous sinus stenting are scarce. In one series of 21 patients stented for idiopathic intracranial hypertension, 10 patients exhibited "stent-headaches" differing from those experienced before treatment, located at the site of the stent, in the mastoid region, and lasting about 3 weeks.


text:
Q: Is the Preimage of an Open Disk a Continuous Action Let the kernel-like operator, $K$, be defined as
$K(f,R) = \text{Closure}({\{x; \lvert f(x)\rvert < \frac{1}{R}\})}$
where $f:\mathbb{R} \to \mathbb{R}$ is a continuous function on the complex numbers with the usual topology. Essentially, the kernel operator finds the preimage of the function on an open disk centered around 0 and takes the closure of it. The purpose of wanting the closure is so I can compare different outputs using the Hausdorff metric which involves using compact sets. Some examples of using this operator are,
$K(z^2, 1) = \{z; \Re(z)^2+\Im(z)^2 < 1\}$
For the next one, let $a = \Re(z)$ and $b = \Im(z)$.
$K(z^2 - 2, 1) = \{z; 1<a<\sqrt{3},   -\sqrt{-a^2+\sqrt{8 a^2+1}-2}<b<\sqrt{-a^2+\sqrt{8 a^2+1}-2}$
$-\sqrt{3}<a<-1,   -\sqrt{-a^2+\sqrt{8 a^2+1}-2}<b<\sqrt{-a^2+\sqrt{8 a^2+1}-2}\}$
The last one was done with some assistance from wolfram alpha to actually deal with the resulting inequality.
Now, the essence of my question is the kernel operator continuous? As continuity of a function depends on the topology you have on its domain and range, I'll clarify what the domain and range I'm investigating look like.
The domain of $K$ is any continuous complex-valued function defined on $A$ where $A$ is a closed ball in the usual topology of $\mathbb{C}$ and the topology is the one induced using the uniform metric. The uniform metric refers to taking the maximum of the difference of the two functions (and this is well-defined due to the extreme value theorem). The usual uniform metric involves a supremum, but as the max will always exist here which one you use doesn't make a difference in this setting. I also chose to restrict the domain of $K$ to continuous functions defined on a compact set because $K$ would not be continuous if you allowed functions defined on a domain that isn't compact. If the domain isn't complete you could have issues come from missing points. If the domain isn't bounded you can have problems by having your sequence of functions smallest place where it intersects your open disk always increase so that the functions converge to one that has not touching the disk while each function in the sequence intersected the disk.
The range will be the closed subsets of $A$ (which makes them compact sets). The topology I'm interested in here is the one that arises from the Hausdorff metric.
The purpose of all this is that choosing large values of $R$ let's you approximate the zero's of the function as you are taking the mainly taking the preimage of a small disk about 0. In fact,
$\bigcap\limits_{i=1}^{\infty} K(f,R) = f^{-1}(\{0\})$
which is what I mean by bigger $R$ getting you closer to the 0 points. Using this instead of finding the 0's directly is the preimage of the set $\{0\}$ is problematic because the zero's of a sequence of functions that converge to another function may be very different than the final function ($f_n = 1/n$ as a good example). Taking the preimage of an open disk avoids this type of issue since it avoids functions almost reaching the boundary.
Now, is this kernel-like operator continuous with respect to f. Specifically, if $\displaystyle\lim_{n \to \infty} f_n = f$ uniformly, then does $\displaystyle\lim_{n \to \infty} K(f_n,R) = K(f,R)$ using the Hausdorff metric.
Edit: Given the current difficulties involving the boundary I have one question related specifically to the issues that occur on the boundary. The question is (still assuming $f_n \to f$ uniformly),
$\displaystyle\lim_{n \to \infty} K(f_n,R) \Delta K(f,R) \subset E(R)$
where $E(R) = \partial\{x; \lvert x\rvert < \frac{1}{R}\}$ and $\Delta$ is for symmetric difference of those two sets and $\partial$ means the boundary of that set. Essentially are the points where those two sets differ only the boundary of the open disk that they are taking the preimage of.

redpajama_set_name: RedPajamaStackExchange


text:
Q: How enable PUT method in apache php 5.0 I have a content in htaccess
Options FollowSymLinks

RewriteEngine on

# if a directory or a file exists, use it directly
RewriteCond %{REQUEST_FILENAME} !-f
RewriteCond %{REQUEST_FILENAME} !-d

# otherwise forward it to index.php
RewriteRule .* index.php
RewriteRule .* - [E=HTTP_AUTHORIZATION:%{HTTP:Authorization},L]

How do I add to enable PUT method?
Thanks

A: Here is the solution which may work for you

*

*First, a utility file to support HTTP digest authentication, which
can be located in the target directory (or a common PHP include
directory if you can set one up): dowload and rename dauth.php

*Second, in the directory concerned, place the following PHP script:
download and rename put.php

*Third, store the following .htaccess file in the target directory,
replacing '/path-to-target-directory' with the domain-relative path
(e.g. if a target file can be read at http://mydomain/x/y/z.html,
then the /path-to-target-directory would be '/x/y'): download and rename .htaccess
.htaccess example:
Options FollowSymLinks

RewriteEngine on
RewriteBase /path-to-target-directory
RewriteCond %{REQUEST_METHOD} !PUT
RewriteRule ^/put\.php$ - [F]
RewriteCond %{REQUEST_METHOD} PUT
RewriteCond %{QUERY_STRING} ^$
RewriteRule ^/put\.php$ - [F]
RewriteCond %{REQUEST_METHOD} PUT
RewriteRule ^(.*)$ put.php?url=$1 [L]

For more info refer: Here

A: Conventions talk about the X-HTTP-METHOD-OVERRIDE header that transports the underlying method to be used (in a POST request).
You can get this request header in your php application to define whether or not you handle a PUT request.

A: No action is required to "enable" PUT requests with apache.
if you mean that you don't receive the data sent with a PUT request - you need some php code like this in your code:
 if ($_SERVER['REQUEST_METHOD'] === 'PUT') {
     $data = file_get_contents('php://input');
 }

since a PUT request will not populate $_POST (obviously, since it's not a POST request).


The 2018 State Employee Combined Appeal (SECA) campaign is from September 4 to October 26! Through the campaign, employees can donate to their favorite charities, participate in special events, and dedicate their donations.
Approximately 1,000 charities participate in the SECA campaign, allowing donors to choose from a wide variety of charities with humanitarian and environmental missions. All charities are represented by one of nine umbrella organizations.
When we donate to a charity that is important to us, it is often because someone in our lives has inspired that gift. Employees can dedicate their SECA donation in honor or memory of someone special.


The General Data Protection Regulation (GDPR) came into effect on 25th May 2018. The GDPR, which has many similarities to the Data Protection Act 1998 which it replaced, is designed to improve transparency in data processing and to protect the rights and freedoms of individuals, in particular their right to privacy with respect to the processing of their personal data.
The GDPR is technologically neutral and therefore applies to personal and special category data in whichever form it is held, for example, in electronic or paper documents. In addition to the data principles, a data subject - that is the individual to whom the information relates - has several rights in relation to the processing of their personal data, as outlined below; these are subject to a number of exceptions and may not always apply in all circumstances.
4. Where the processing is carried out automatically for the purpose of evaluating matters relevant to that person, to have the logic involved in the decision taking explained.
If you want to know what personal data Gas Safe Register is holding/processing about you, or information about a specific incident you can request this information by completing our Subject Access Request Form. The completion of this form is not compulsory but is designed to help you provide us with the information we need to deal with your request. Requests made in other formats will also be accepted.
Download and complete the form and then send it, with the appropriate identification documents, either to the postal address given in the guidance notes or by email to enquiries@gassaferegister.co.uk marked for the attention of the Business Improvements Manager.
Proof of identification is required when making a request to confirm that you are the data subject, this is the individual to whom the data refers. This is so that we do not disclose any data to someone who is not entitled to receive it.
If you are making a request on behalf of the data subject e.g. you are a solicitor acting on your client's behalf, you will need to provide proof that you have your client's consent to request and receive their personal data. This may be a signed form of authority from the individual.
When providing us with details of the information you are requesting, please ensure that you are as specific as possible and provide as much detail as possible.
Gas Safe Register has one calendar month in which to provide the data you have requested. This starts the day after Gas Safe Register receives all the information it needs to confirm your identity, or your right to request a third party's data and we are satisfied that you meet the criteria for the disclosure of data under Data Protection Legislation.
Will you receive all the data that relates to you?
It is important to note that it is not always possible to know what information is held about an individual when a search is made. There may be times when we hold personal data about an individual which we cannot disclose to you. This may be because it is not possible to disclose your personal data without disclosing a third party's data and either the third party has refused to give consent for their data to be disclosed or the third party's data is awarded a degree of confidentiality which means the data cannot be disclosed.
There are also other exemptions in the GDPR which mean that personal data can be withheld. You may also receive documents that may have data redacted (blacked out).
If you remain dissatisfied with our response to your request, you may submit a complaint to the Information Commissioners Office (ICO). More advise on how to do this is available on ICO website www.ico.org.uk or by calling its helpline number 0303 123 1113.
You should be clear about exactly what information we hold that you believe is inaccurate and how Gas Safe Register should correct it, providing evidence of the inaccuracies where available.
Data Protection legislation only obliges organisations to keep information factually correct and cannot be used to alter or remove opinions unless those opinions themselves are based on inaccurate factual information.
An individual has the right to erasure of personal data supplied to a data controller in certain circumstances. The right to erasure does not apply to registration data collected for the regulatory purposes or data relating to complaints against businesses or engineers. There are limited circumstances where this would apply. Any requests for the erasure of data can be made verbally or in writing. Requests made in writing should be sent to the address below stating what you require deleting and the reason why.
Where a request is made verbally verification of the caller will be required. In all cases we will request that proof of identity is provided before we make any changes, especially where the request is made by persons other than the responsible person for a registered business or members of the public. The right to erasure does apply to any marketing communications. Where we agree to delete your data, this may result in the termination of our services.
An individual has the right to restrict processing where the accuracy of the data is contested, where the processing is unlawful, where the personal data is no longer needed by the data controller or where the individual is contesting the grounds on which the processing is taking place. This is not an absolute right and only applies in certain circumstances. This is an alternative to requesting the erasure of their data.
The right to restriction of processing does not apply to registration data collected for the regulatory purposes or data relating to complaints against businesses or engineers. There are limited circumstances where this right would apply. Requests for the restriction of processing can be made verbally or in writing. All requests made in writing should be sent to the address below stating what data we should stop processing and why.
Where a request is made verbally verification of the caller will be required. In all cases we will request that proof of identity is provided before we make any changes, especially where the request is made by persons other than the responsible person for a registered business or members of the public.
An individual has the right to data portability, that is, to receive the data they have provided to the data controller, in a machine-readable format, as well as to have that data transmitted to another controller. It allows them to move, copy or transfer personal data easily from one IT environment to another in a safe and secure way, without affecting its usability.
The right only applies to information an individual has provided to a controller. Requests should be made in writing and sent to the address below, stating what data is to be transferred and to whom. In all cases we will request that proof of identity is provided before we transfer any data to a third party, especially where the request is made by persons other than the responsible person for a registered business or members of the public.
An individual has the right to object to processing carried out on the grounds of public or legitimate interests, or where the processing relates to direct marketing or where the processing is in relation to automated decision-taking.
The individual can ask the data controller to ensure that no decision that could significantly affect the individual is based solely on processing by automatic means. An individual can make an objection verbally or in writing. Requests made in writing should be sent to the address below, stating what data you object to Gas Safe Register processing and the reason why. Where a request is made verbally verification of the caller will be required.
In all cases we will request that proof of identity is provided before we make any changes, especially where the request is made by persons other than the responsible person for a registered business or members of the public.


I woke up at 1 p.m. today. Seriously. I slept for more than half a day. It is already dark outside, and I haven't left the house, I haven't eaten a thing and I haven't talked more than maybe fifty words to anyone the whole day. Halloween is over now. We didn't fix the house so it would be scary. I didn't walk Trick or Treat for almost the first time in my life. Halloween is over and I didn't even notice it when it was here. And that scares me more than all the fake spider web and chopped of hands in plastic. Because I love Halloween and this year I just let it pass. I went to see The Nun, which may be a little Halloweeny thing, but I see horror movies every month, every week if the year, so that didn't wake up any special vibes. It was a great movie though, and I was happy yesterday. Now I am not. This is the first day of November, and it isn't the best start. Or it is, because things could have been a lot worse since November after all is the most depressing month of the year. It is not warm holiday summer, it is not cozy snowy winter, it is not green hopeful spring. It is the late fall. It is not a start of anything, it is the beginning of an end but it is not yet right in the end, because the end is good and before it there is nothing. Like November. The month is cold, but not so much that it snows, the month is dark, but not in December so you can't drink a lot of hot chocolate and light candles and the month is in the end of the year but not precisely in the end (as said before) so there won't be a Christmas or a New Year's Eve. Just a bunch of grey and people who have given up. November is the month when a lot more serial killers than in any other month are born. Coincidence? I don't know, but you got to admit, not many people are looking forward to November. You have heard those who like the beginning of a year because everything is new, those who like spring months like March and April and May. Most persons love the summer. And sure a lot like the fall. But always September and October and then there is just empty space, before the people who love December shows up. Nah, November will never be a liked month. All I can do the entire month to keep myself alive and well is escaping. Constantly wearing headphones listening to music, or reading a book, or ten books. Or studying and think of what will come next.
I actually don't know where I was going with this. I just wanted to tell you how I feel, but there is really not a point in this post whatsoever. Maybe I need some quotes? The ones that opens a thought. Or sometimes a whole mind.
"We cut and kill flowers because we think they're beautiful.
The kind that opens the gate to the tears.
The kind that everyone understands.
The kind that gives perspective.
The kind that you never understand, or everyone have a different understanding on (yes, it is Shakespeare).
Finally, the kind that makes you stronger, hopefully. Just a little bit.
Alright, I am tired now.


text:
Support & Office Services
Development Funding
Digital Enterprise Centre
Office Down-sizing
Cases Of Growing Companies
Investment Application
Glasgow Office Accommodation | Strathclyde University Incubator
Brand Creation and Development
Glasgow City Council Funding Programmes
Making Money From Your Business
Planet Eureka Seminar
Risk Assessment, Health & Safety
The Institute of Nanotechnology
The Truth About Marketing
True North Innovation
University of Strathclyde Dragons Den
Strathclyde University Incubator Ltd. is registered at 50 Richmond Street, Glasgow, G1 1XP. Company number is 108665 Vat No. 5563113 55
There are lots of places for young businesses to set up and start trading successfully.
Some of them will be stand-alone offices with absolutely no resources for them to benefit from and some will be managed offices where people will answer your phones and provide you with a fax machine and a light. We're neither of those.
Our main aims are to support young businesses to flourish in their own areas of expertise and to offer help and advice where it's needed. We know what the hurdles are and we have helped many companies get over them in the past. We understand that you are the experts in your field but we also know only too well that experts in one area can be less skilled in other areas and that's where we can help.
Businesses that are based here and those who have left have benefited from an environment that wants them to succeed.
We can also put our Sunday best on and become all formal and tell you that we set up to meet the following objectives:
To create a supportive structure for new companies to minimise the failure rate and thus accelerate the growth of new companies in Scotland.
A means of encouragement for the transfer of technology out into the commercial world from academic institutions.
The creation of opportunities for commercial investors with the long term objective of Strathclyde Incubator being profitable in its own right.
Everything here is geared to your success. Be it our board of directors who are true experts in their fields, our management team that is accessible every day to support you or it could be the general vibe of other businesses who are in the same boat as you – they want success and they believe that they can get it by being based here.
© 2012 Strathclyde University Incubator Ltd.
Website Design by Red Paint

redpajama_set_name: RedPajamaCommonCrawl


We have a number of different ways in which you can transfer currency abroad or back to the UK. Your account manager can explain these in more detail and help you decide which option is right for you.
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Hello everyone! Welcome to my webpage. This site is dedicated to helping people who suffer from food allergies or health conditions be inspired to eat better and become more active. Please reach out to me with your own tips and tricks- I'm always eager to learn!


text:
Schachdorf Ströbeck (česky doslova Šachová vesnice Ströbeck), do roku 1991 jen Ströbeck, je vesnice a od 1. ledna 2010 část města Halberstadt v německém Sasku-Anhaltsku. Má do středověku sahající tradici hraní šachů, která je v Německu uznávána jako nehmotné kulturní dědictví. Ve Ströbecku působí také šachové muzeum. Na celoněmecký seznam nehmotného kulturního dědictví německá komise UNESCO Schachdorf Ströbeck zařadila v prosinci 2016.

První zmínka o Ströbecku pochází z 20. října 995, kdy se ves objevuje v listině císaře Oty III. Hrát šachy místní obyvatele podle legendy naučil zajatec z řad šlechty, údajně markrabí Gunzelin z Kuckenburgu, kterého měli za úkol ve vesnici hlídat. Poprvé je zdejší hraní šachů v pramenech doloženo roku 1515, podrobnější popis existuje v první německé šachové knize Das Schach-Spiel oder König-Spiel, kterou napsal vévoda August von Braunschweig-Wolfenbüttel a vydal ji roku 1616 v Lipsku. K roku 1689 je doloženo veřejné předvádění šachových partií, při kterých v roli šachových figur vystupují kostýmovaní obyvatelé obce. Ve zdejší škole (pojmenované po slavném šachistovi Emanuelovi Laskerovi) jsou šachy od roku 1823 povinné. Až do přelomu 19. a 20. století se zde však hrávaly podle místních zvyklostí poněkud odlišných od běžných pravidel šachu; místní například nepoužívali rošádu a výchozí postavení figur bylo jiné, než je obvyklé.

Externí odkazy

Halberstadt
Šachy
Části měst

redpajama_set_name: RedPajamaWikipedia


text:
Classified documents found at former VP Mike Pence's Indiana home
Francesca Chambers , Erin Mansfield | USA TODAY
Classified documents found in former VP Mike Pence's residence
Around a dozen classified documents were found in former Vice President Mike Pence's Indiana residence in the latest string of discoveries.
Claire Hardwick, USA TODAY
A handful of classified documents were found at former Vice President Mike Pence's home in Indiana and the FBI retrieved them last week, a representative for Pence wrote to the National Archives in letters this month.
Pence's lawyer characterized the documents as "a small number of documents bearing classified markings that were inadvertently transported to the personal home of the former vice president at the end of the last administration." He said they were found Jan. 16 and placed in a secure safe until they could be returned to proper authorities.
This is the latest in a series of discoveries involving classified documents, a widening issue that underscores what security analysts have told USA TODAY: The U.S. system of safeguarding classified presidential documents is in urgent need of improvement, especially during the critical period when one administration hands over the White House keys to another.
Last year, classified documents were found at an office at the Penn Biden Center, and Biden earlier this month voluntarily submitted to an FBI search where agents turned up additional documents.
The Department of Justice executed a search warrant on President Donald Trump's home last year after a long back-and-forth over what documents the former president had at his Mar-a-Lago estate. Trump refused to cooperate with the Department of Justice in that case, a marked difference from Pence and Biden.
Attorney General Merrick Garland appointed two special prosecutors to oversee the Biden and Trump document cases in order to shield his Department of Justice from politics, since he reports to the president.
Biden: Revelations grow on Joe Biden's handling of classified documents; here's what we know so far
Trump: Mar-a-Lago in Florida searched by FBI in probe into handling of classified documents
What Pence said in the past
Last year, Pence repeatedly denied any knowledge of classified documents at his home. In August, when The Associated Press asked Pence if he took any classified documents to his home, he responded, "No, not to my knowledge." In November, Pence told ABC News, "There'd be no reason to have classified documents, particularly if they were in an unprotected area."
The Jan. 18 letter from Pence's lawyer said the former vice president was "unaware of the existence of sensitive or classified documents at his personal residence" and that he "understands the high importance of protecting sensitive and classified information and stands ready and willing to cooperate fully with the National Archives and any appropriate inquiry."
The Department of Justice "requested direct possession" of the documents on the evening of Jan. 19, and FBI agents collected the documents from a safe in Pence's home that night, according a letter dated Sunday.
Garland declined comment, as did the National Archives. Pence's lawyer was out of the office.
Members of the Senate weigh in
Members of the Senate, which Pence presided over as vice president, were quick to weigh in.
Exclusive: Mike Pence predicts 'better choices,' not Trump, as the GOP's 2024 nominee
Opinion: What if I told you all this fuss over classified documents won't ultimately matter?
"The law applies to everyone, presidents, former presidents, and former vice presidents," said Sen. Elizabeth Warren, D-Mass. "The Justice Department will conduct appropriate investigations and make certain that the law is applied equally and fairly to everyone."
She said the handling of classified information is a matter for the DOJ, and that the law is clear in this area but that it needs to be enforced.
Mitt Romney, R-Utah, told USA TODAY that someone ought to be looking at the homes of pretty much every living president and vice president "very carefully to make sure they don't have something inadvertently – or purposefully – there, which could be threatening to our security."
Carl Tobias, a professor at the University of Richmond School of Law in Virginia, said that while all the recent cases in question involve high-level officials handling confidential documents, Pence's is similar to Biden's because there are so few, and because of how he reacted.
The FBI search warrant executed at Mar-a-Lago turned up more than 11,000 government documents and pictures without classification markers, including 31 "confidential" documents, 54 "secret" documents and 18 marked "top secret."
"Hopefully there are only a small number and they're not critical documents," Tobias said of the Pence documents. "But he seems to have acted very similarly to Biden when he learned of this."
CNN and Fox News first reported the discovery at Pence's home.
Systemic issues?: Biden and Trump documents expose wider problem: Missing classified records not uncommon
Contributing: Josh Meyer, Rachel Looker, Ken Tran, David Jackson and Kevin Johnson.


text:
Five amazing communities win $15,000 Let's Play playground grants!
The results are in! We received nearly 120 entries for our nationwide video contest, which was sponsored by Let's Play, a community partnership led by Dr Pepper Snapple Group to get kids and families active nationwide. After selecting 10 finalists, we asked communities to compete for votes in an interactive voting competition, with the top five winning a $15,000 playground equipment grant.
For the last 20 days, finalists have been working hard to mobilize their communities and get out the vote. We've blown away by the response and commend all the entrants and finalists for their commitment to creating a great place to play.
And now, a hearty congratulations to our five winners:
A M Waddington Elementary serves Riverside, Rhodes Island, a tight-knit community within the city of East Providence. Currently, their only play equipment consists of a triple pull-up bar and some basketball hoops.
Capitol Hill Elementary is located in Southwest Portland, Oregon, and serves more than 350 students. Their grant will go towards a playground so their children aren't confined to playing asphalt games.
Dunbar Intermediate School is housed in what used to be a middle school, but when the school board consolidated schools, the third, fourth and fifth graders who came to the school had to nowhere to play.
O.K. Ward Park (Brooklyn's Playground) is a public playground in Pocatello, Idaho that residents want to make "all inclusive" so that handicapped children can have a place to play. Residents supporting a little girl named Brooklyn Fisher, who has spina bifida came out in force to support the project.
Martha Lake Elementary in Lynnwood, Washington has to remove their old playground because of safety concerns, but had no money to replace the outdated equipment.
See all the finalists here.
kaboom! news, video contest, video, grants, lets play, dr pepper snapple group
What do a toddler, a neuroscientist, and a Yoruban High Priestess all have in common?
How to make ice cream in a coffee can
Why not turn a vacant house into a giant ball pit?
The beautiful story of a boy and his cardboard box
Sign up for emails about new grant opportunities
Not now, thanks!


Started this discussion. Last reply by Eileen Mar 26.
Eileen replied to Eileen's discussion Rink retrofit?
"Above photo is March 14th. Once I pulled the liner out I could see the huge gap between the boards in the deep end and the bags of dirt that had been flush with it on fill day. Definitely need to do a better job with bracing the deep end…"
"Totally empty and liner pulled out. After the last post boys skated all weekend but then by March 14th ice was thin. I was able to punch a hold in it and put in my pump and I drained on and off. Drained by March 17th. There…"
Daniel robitaille replied to Eileen's discussion Rink retrofit?
"Good time to make notes for next year (low spots for filling) hight spots to lower. bracing changes, Backboard location to keep pucks in etc... Walkway upgrade Change out OSB boards for plywood Good skating Dainel"
"Thanks Daniel. The rink may be self correcting as the weather has warmed up and I got some loss out of the liner tear which was just enough to pool in my yard. I do have access to the bottom of some of the boards so will keep that in…"
"Don't panic it holding the ICE for now it will hole the water"
"Pack the snow Along the side your worried about, Even water it a bit to turn it into ice. This will Hold till melt Ask yourself where is the snow melt going (into the neighbor) His problem is not from your rink but you don't want to add to it…"
"Looks awesome Tom! We still haven't gotten thick enough ice to skate here in the Chicagoland area. (Which has meant stick and leaf problems; and then yesterday we got several inches of snow so now I have slush, but that is for…"
Eileen replied to Steve's discussion Is it time?
"Nice looking rink Daryl! Totally jealous, esp the skating! Steve, I am experiencing the same regarding the rink and early fill. In addition I had raccoons track mud onto the rink. And the weather is even warmer now than previously…"
"Clarification: Temperatures mentioned in my post are Farenheit!"
"I have a question regarding topping off. I started filling Wednesday and filled overnight. It usually takes me 24 hours to fill by hose. Thursday morning I noted water on one side of the rink and back/high ground corner not…"
"20' x 48'. Frame up this weekend but I still need to do the various frame stabilization and gap control measures which will take me about another week. My set up does not look near as nice as Kris's above! So hoping…"
"Full disclosure: this is only my second year so I am a newbie myself. 1. I have found a sunny day to be a good resurfacer. Otherwise, I just use a hose nozzle on shower function (at regular temperature, I do not have heated water)…"


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Sour notes: Behind the music of Richard Scrushy at HealthSouth
By Bob Sims | rsims@al.com
Richard Scrushy, during his days with his band, Dallas County Line.
Macey Taylor
remembers it, he and other members of
Dallas County Line
, the country band
Richard Scrushy
fronted and formed with a mix of
HealthSouth
employees and Nashville pros, traveled like stars.
Most of the time, the gigs were HealthSouth conferences or company meetings -- events that would make the use of company aircraft acceptable, Taylor remembers.
Dallas County Line was invited to sing -- lip-sync, actually -- on a cerebral palsy telethon in Los Angeles hosted by sitcom stars John Ritter and Henry Winkler. The jet flew from Birmingham to Nashville to pick up the rest of the band and then to LA, where Taylor recalls they stayed in the same hotel the Golden Globe Awards show was taking place.
This was HealthSouth's heyday in the mid-1990s, before the company's culture of fraud was exposed, before anyone asked hard questions about how the firm spent its cash on nonbusiness activities such as Scrushy's country band. But that spending is getting new scrutiny in a Jefferson County Circuit Court civil trial that will enter its second week on Monday.
The centerpiece of a shareholder suit seeking $2.6 billion in damages against Scrushy is that he directed an long-running accounting fraud that almost torpedoed the Birmingham company before being exposed in 2003. A parallel contention is that he operated HealthSouth like his own piggybank, using the company's fleet of jets to whisk friends and family members around the country and sponsoring a girl band called 3rd Faze whose members got breast implants paid for by the company.
[FLASHBACK: The rise and fall of 3rd Faze]
In his defense
Scrushy's lawyers have pointed out that the former CEO reimbursed the company $800,000 for his personal use of corporate jets and that he was acquitted in Birmingham federal court in 2005 on scores of criminal fraud charges. Scrushy and his attorneys also have said many of his entertainment ventures were designed to promote HealthSouth and were initially considered savvy marketing ploys.
Scrushy himself is expected to testify this week. Back in 1996, he told a reporter that he would never let the band get in the way of his real job at HealthSouth.
His involvement in Dallas County Line -- named for the Selma native's home county -- resurfaced this week when plaintiff's lawyers played a video of the band's best-known song, "Honk If You Love To Honky Tonk," to chuckles in the courtroom. [Sample, and purchase, music from the Scrushy band on Amazon]
Scrushy's efforts to achieve stardom with Dallas County Line have always represented a fascinating footnote in his rags-to-riches story, even though it may never be established that company money was diverted to its operation. Scrushy himself was wealthy enough to fund the band, having collected total compensation of $106 million in 1997 alone.
Taylor, who has not testified in the civil case, was there for the band's early years. From the start, the lifelong musician was impressed with the band's equipment and Scrushy's drive to succeed. At Dallas County Line's first gig at the Birmingham Country Club, Taylor remembers being blown away.
"There was enough PA equipment there, you could have played Boutwell Auditorium," Taylor said.
In the band's rehearsal space, a HealthSouth-owned building on Birmingham's Southside, Taylor remembers cameras that were fixed on Scrushy so he could watch himself perform on a video screen.
2 jobs at once
Taylor joined the band in the fall of 1994 after Scrushy had trouble playing the piano parts Nashville session musicians played for the demos of Dallas County Line's first album, called "Rich Man's Dream."
After he joined the band, Taylor said, Scrushy also invited him to work for HealthSouth. Taylor was working in video production for a Birmingham advertising agency at the time, but was told he was in luck because the health care company needed a video production expert.
When the person hiring Taylor asked how much he expected for his annual salary, he gave a figure below $50,000. But he soon realized he should have asked for more, because he might have gotten it. A few months later, he told Scrushy he would like a raise, and Scrushy said he would take care of it in the new year. When Taylor broached the subject again at a company Christmas party, Scrushy erupted, telling Taylor he couldn't give everybody a raise.
Taylor wasn't the only HealthSouth employee toiling away in the band. The drummer was Bill Owens, who became the company's finance chief and a key player in the fraud at the company. The imprisoned Owens testified via video deposition last week in the civil trial.
Ken Livesay, once an assistant controller who helped engineer the company's accounting fraud, played guitar for the band. Livesay was put on probation after confessing to fraud-related charges.
The HealthSouth band members got treated differently from the Nashville pros, Taylor soon learned.
During one photo shoot, Scrushy directed the HealthSouth band members out of the frame after a few pictures. He and the Nashville musicians continued to pose for dozens of more photos, Taylor remembers. Later that night, Taylor asked Scrushy why the rest of the band wasn't included.
"Macey, are you famous?" he remembers Scrushy saying.
Taylor said there were times when the Nashville band members would fly in to Birmingham for practice or a gig and then take limousines over to Scrushy's Vestavia Hills mansion for steak cook-outs -- with only the Nashville band members invited.
High notes, low flights
Taylor also remembers another aspect to the airplane rides to Nashville. He said after flying in a HealthSouth jet to record tracks for an album, Scrushy became convinced that his inability to sing the high notes was due to the high altitudes he experienced in his frequent plane trips.
"Richard had the pilot fly much lower than usual in order to protect his voice," Taylor said.
Despite all the efforts, Dallas County Line called it quits after two albums and a music video for "Honk If You Love to Honky Tonk." That song came out in 1995.
Taylor left the same year, one year after joining both the band and the company. He is still a musician-for-hire and has his own television production company, Taylor Broadcast Services, in Birmingham.
He doesn't miss the HealthSouth days and is not fond of his time in Dallas County Line. He once had two denim jackets -- one black and one blue -- emblazoned with "Dallas County Line" on the back.
"A carpet layer came to my house and saw something related to Dallas County Line and said he was a big fan of the band," Taylor said. "I gave him those jackets because I didn't want them anymore. He seemed happy."
mtomberlin@bhamnews.com
Rich Man's Dream by Dallas County Line


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By Vince Tuss
February 19, 2014 — 6:52am
A CBSSports.com report on the Los Angeles Lakers and Dallas Mavericks pursuing Kevin Love ahead of the NBA trade deadline got quite the reaction from Mavericks owner Mark Cuban on Tuesday night: No, no, no.
"If you read about it, you know it's not true. I don't know if we got the Beach Boys booked, "Cuban said before Dallas lost to Miami 117-106, according to the Dallas Morning News in a post headlined "Mark Cuban squashes crazy Kevin Love speculation." The Beach Boys reference is to Kevin's uncle Mike, a founding member of the band.
Calling it laughable, ESPNDallas.com also pointed out all the obstacles:
"The first is that there is "no way" the Minnesota Timberwolves are dealing Love before Thursday's trade deadline, as a source told CBSSports.com, which makes the splashy headline about the Mavs and Los Angeles Lakers attempting to put together packages for Love pretty much pointless.
Another problem: Even if the Timberwolves were considering trading Love, what the heck could the Mavs offer to keep Minnesota GM Flip Saunders from hanging up and/or cracking up? The Mavs can't offer future first-round picks, the most valuable currency in today's trade market, because they owe Oklahoma City a top-20 protected first-rounder."
Ken Berger's report cites that "it is widely known around the league" that Love and his agent "are determined to get him to a major market." But even before Berger says that, he writes "the Timberwolves have given no indication they's consider moving the All-Star forward."
And four paragraphs later, Berger again throws cold water on his own report, citing "a person familiar" with Flip Saunders' strategy that there is "no way" the Wolves will trade ahead of the deadline.
State-title winning Fargo coach fired after text message to team
A.J.: Ortiz didn't thrive in Minnesota because of Twins
StribSports Upload is where you'll see what other people are saying about Minnesota sports. It could be a report from another city's media following a game. It could be a blog or video from somewhere in Minnesota. It could be serious or funny, on point or off the wall. It could be something you tell us about. Send stuff to Upload here. All correspondence to Upload is on the record unless requested otherwise.
St. Cloud Boogaloo Bois member gets 2 years in plot to attack Minnesota Capitol
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Sometimes taking a knee can blow up in your face
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Final score 108-94. Yes, it was a high school football game
Iowa didn't get a head start on the prep basketball season and start games this fall. That's a final score from a state football semifinal game played Thursday morning.
Watertown-Mayer ends three-year football losing streak in convincing way
Not only did the team break the streak, it happened against an opponent that had a winning record this season and beaten the Royals soundly over the last two seasons.
Take your mind off Gophers' horrid ending with this miraculous (almost) score
The jaw-dropping play included eight laterals and 55 yards. It was so good we think you can overlook the fact that it didn't count. (Lateral No. 4 is the best.)
Gophers bowl projections? They're already being made
We're going to bet that you haven't been thinking yet about a Gophers bowl game destination and opponent. But other people have.


Gospel music artist and renowned music producer and Guitarist Kaystrings is back. Contemporary Christian musician, Ojo Noah Oluwakayode popularly known as Kaystrings returns with a new single. The new single is titled "Sovereign King (Alagbara)" comes off his forth coming album:Encounter which is scheduled to be released this year.
Kaystrings made his debut in 2016 with the song "Na You I Dey Praise" and followed that with "The Most High God" that year. His last song released in 2017 was the song "This God". He returns this year 2019 ready with fresh contemporary sound and working towards dropping an album project.
"Sovereign God" is a alternative praise song that will many hearts inspired. Fused with English, Yoruba, this song brings back alternative music to the surface and will be well accepted and become a favorite on radio, media and with worshipers everywhere.


The cold winter season can be a great time to enjoy your spa. Read about some ideas to help properly maintain it during this time or how to completely winterise your spa if you choose not to use it during the winter months.
Canadian Spa Company offer Spa servicing and repairs on all makes and models of hot tubs and Swim spas. Have a look at our Maintenance Packages to find the one for you.
Take advantage of aSpa Health Check from Canadian Spa Company.
Simply dip your test strip into your spa water and enter the colours shown into the 'Water Test Centre' screen if the app. Instantly you'll have the list of products and the quantity of products needed to balance the alkalinity, pH and chlorine levels in your spa.
Hot tub water may freeze up in extreme cold weather if there is loss of power to the spa or spa has been drained down but pipes not cleared of excess water. Freezing pipes can result in pipes/component damage so it is important to thaw the ice and empty the spa as soon as possible until an experienced spa engineer can visit to repair.


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A Brutal Sight of War è un album dei Disfear pubblicato nel 1993 dalla Lost And Found Records.

Tracce

Collegamenti esterni


Creating gestures in Altia is indeed possible. Since implementation varies depending upon the gesture, the GUI design, and the performance of both the hardware and its touchscreen, we do not have generic documentation to provide.
If the coordinate delta (the difference between the 2 coordinate locations) of the press event and release event is large when the release event comes in, this should cause a scroll (or if you have not detected an release event yet, but the coordinates are changing, that should cause a drag/scroll event).
If you detect a release up event, you need to calculate some things based upon time. If the delta is large, and the time is short, that should cause a fling event (a fling event itself usually sets a "destination" scroll value to be much higher than the current scroll position and kicks off a time-based scroll event to arrive at that location automatically as a result of the "fling" event). Conversely, if the delta is large but the time between press and release is long (or if the delta is simply to small for a fling) this should not fling, but maybe just nudge it a small bit from its current location to make it "feel/look" smooth.
What you scroll, how you scroll, (essentially, what moves, and what it looks like) is all fully customizable and created with objects in Altia Design. Embedded GUIs are not windows in an OS, so there might not ever be a scrolling region, or if something does scroll/fling, it will need to do it in a custom way per the design of that interface, so this is why the overall implementation can be highly dependent upon the design intent/behavior of the screen in question.
input. If you would like further support on this topic, and would like to see a specific example fleshed out for your needs, we can continue to support you on implementation (please submit a new request/ticket to ask for additional support on this).
As for multi-touch, that gets even more differentiated at the driver level, since it would depend upon the format/output of the touchscreen controller when receiving multi-touch events (assuming the touch screen in question supports multi-touch of course). However, this highlights more flexibility in the Altia tool chain. For example, when generating for a target with an OS, let's say Android, you can choose to stop at the high level, creating your Altia GUI executable as just an Android "app" and let Android tell the GUI it has detected a swipe, or you can bypass the OS entirely and have your application talk to the hardware to do custom stimulus/logic based gestures as discussed before. The last statement also highlights the ability to have DeepScreen generate code for either high level apps or deeply embedded hardware optimized GUIs that require no OS at all.
Of course, if you're doing the Stimulus/logic based events for multi-touch, the format of the touchscreen controller's output would have to be properly extracted and sent to Altia Design as some form of Left Down and Left Up event structure. You can see that this question can only be best answered if a specific implementation is in play.
In the end, this all happens in code, and nothing is left to magic. Since it's very flexible (and variable) it's really up to you/your project what the best way to tackle it might be. However, Altia has a lot of mind-share to support you on this decision and/or implementation process.


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Cabruy o San Martín de Cabrui (llamada oficialmente San Martiño de Cabrui) es una parroquia del municipio de Mesía, en la provincia de La Coruña, Galicia, España.

Entidades de población
Entidades de población que forman parte de la parroquia:

Despoblados
 A Tieira da Bauca (A Tieira da Baiuca)
 Raíña

Demografía
{{Gráfica de evolución|tipo=demográfica|anchura=600|nombre=Cabruy|2000|228|2001|236|2002|236|2003|217|2004|221|2005|216|2006|209|2007|205|2008|204|2009|198|2010|199|2011|198|2012|195|2013|197|2014|193|2015|192|2016|195|2017|189|2018|183|notas=}}

Referencias

Enlaces externos

Parroquias de Mesía


I'm very pleased to announce "SevenVG" theme which is the First and Best Windows 7 look-like theme for Windows XP and all other Windows 7 look-like themes. 30 Jan - 4 min - Uploaded by Team TNE This is a video how to make Windows XP look a lot like Windows 7 Operating system. This is. 16 Jan Generally, I don't think and search for Windows XP related themes and applications since I have been using Windows 7 and Vista for some.
20 Jul Select the items you which to change, click "Change Icons," and browse to the location of new icons that are part of the Windows 7 theme. B. For Windows XP – Right-click on the desktop, select Properties and choose "Customize Desktop" under the Desktop tab. Copy the files from the zip folder's themes folder into the \Themes directory. Right-click any empty space on your desktop and open Personalize. In the window that opens you should see a new Installed Themes category, which includes Luna and Luna Aero. Pick Luna for that pure XP look. 20 Nov You can't just grab the files from Windows 7's themes gallery and set them as your own. You can, however, use tools like 7-Zip and John's Background Switcher to pull out each theme pack's files, install them, set them to rotate (a la Windows 7), and even get the sounds, cursors, and other elements running.
27 Dec So what if you could not upgrade your computer to Win7. You have several Windows 7 themes for XP available on the Internet. This article. Download best Windows 7 theme for Windows XP FREE!. 25 Jan Guide to customizing the look of the Windows XP desktop with Windows 7 themes. SevenVG RC (Windows 7 Theme) (Windows), free and safe download. SevenVG RC (Windows 7 Theme) latest version: Transform Windows XP into Windows 7. Hey,i used to have windows XP Professional and i loved the XP theme,but i now have windows 7 and i couldn't find an XP Pro theme on my.
24 Aug Get free featured desktop themes for Windows 7, Windows , Windows RT , and Windows We are not going to get our hands on much anticipated Microsoft Windows 7 anytime soon, but we can enjoy the look and feel now on our Windows XP & Vista. 27 Jun then scroll down to the bottom and choose windows classic theme then it will to change it back just click on windows 7 basic theme and it will. 13 Sep How to install and use 3rd party themes in Windows 7 . they had to change the windows xp slogan after 9/11 from "Prepare to Fly" to "Yes You.


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Cedric Godart
Who is Cedric
Cedric Godart » Home and family
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Learn about the most captivating beverage known as coffee
Coffee can be described as one of the most popular beverages all around the world. An element of romanticism is often associated with this beverage and people always have the luxury of choosing from a wide range of choices. Almost a third of world's population has been consuming coffee and many people cannot even think of starting a day without this beverage. The ever rising numbers of cafes or coffee shops clearly show the popularity of this beverage and it has been estimated that more than 7 million tons of coffee are produced every year. Arabica and Robusta are the most common plants from which it is produced. 75 to 80% of coffee is produced from the Arabica plant and Robusta plants account for 15 to 20% of the total coffee production in the world.
A good number of legends and stories surround the first use of this beverage. The most popular legend says that it was discovered in the 9th century when an Ethiopian goat herder known as Kaldi found out that his lethargic goats got excited after they had nibbled the red berries from an evergreen tree. Kaldi informed this matter to an abbot of a local monastery who made a delicious drink using these berries and it kept him awake for long hours of evening prayer. Gradually, the energizing effects of this drink began to spread and the news became immensely popular in the Arabian Peninsula. Anyhow, the earliest substantiated evidence of people drinking coffee appears to have been in the middle of the 15th century, in the Sufi monasteries of Yemen. In the 16th century, coffee became popular a popular beverage in Persia, Turkey, Middle East and Northern Africa as well. Later, it spread to the Balkans, Europe and Indonesia and then, to the United States.
Why do people love drinking coffee?
The mind blowing taste and aroma of this beverage have always played a major role in making it amazingly popular. Apart from these two aspects, it also offers a wide range of health benefits. Caffeine, a dominant component in coffee improves the energy levels and makes people smarter and dynamic as well. It can also be used to burn fat because this beverage improves the metabolic rate and it can be used to lower type 2-diabetes. This drink protects the liver with utmost efficiency and the antioxidants available in coffee fight against the deadly dangerous free radicals in the human body. Different diseases like cancer, Parkinson's disease, Alzheimer's disease, stroke, heart diseases and depression can be controlled using this wonderful beverage. All these aspects clearly suggest that it is one of the healthiest beverages on the planet.
Most popular coffee drinks
Various methods are being employed to make different types of coffee and taste, color and aroma differ with each type of coffee. People use different ingredients like steamed milk, frothed milk, cinnamon, chocolate, whisky, brandy and ice-cream to make this beverage really unique and the quality of the coffee beans also vary with different varieties. Some of the most popular coffee drinks include Cappuccino, Americano, Cold brew, Cuban coffee, Espresso, Filter, French press, Greek, Iced, Instant, Irish, Mocha, Turkish, Vietnamese, Frappuccino, Latte and Macchiato.
Coffee has become an unavoidable aspect in lives of millions of people all around the world and various studies show that the sales are increasing more than 20% every year. The captivating aroma, mind blowing taste and beautiful color make this beverage truly inimitable and it is world's second most popular drink after water. The recent trends clearly suggest that the popularity of this beverage is going to reach new heights in the immediate future.
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There Is Always Time for A Cup of Delicious Tea!


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Omics! Omics!
A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery
Nostalgic for Fly's Eyes
Kumar Thangdu's mission of prodding me has contributed to a bout of nostalgia for one of my graduate student rotation projects. He asked in a tweet how I'd allocate funds if I was given stewardship of a billions in grant money. If you want to get some big results but are willing to be very patient, then a great way way to invest is in model organisms. As a rotation student at Harvard, I spent several months pushing Drosophila melanogaster, the not-so-humble fruit fly.
I had planned to leave my experimental career, and experimental frustrations, behind in Newark. However, the graduate program I was in at Harvard had minted only one prior computational-only Ph.D. (Jim Ostell, the force behind NCBI for many years). Having someone slide through without ever doing a single wet experiment was still controversial, so the edict was laid down that I needed to go through one experimental rotation.
Luckily, I had been introduced to Bill Gelbart, one of a cohort of Drosophila geneticists in the department (his premature death last year was a terrible surprise). Bill was part of a multi-site group trying to land a grant to digitize all Drosophila genetic knowledge into FlyBase, with the relational database itself falling into Harvard's sector. Bill knew my crazy informatics leaning, and asked me to review the schema. I had to confess I had never looked at such a document nor did I understand relational technology, but he said not to worry about that and gave me the document anyways. I can't remember if I found anything intelligent to say about the schema, but it opened a line of communication.
In undergraduate genetics we had some fly labs, and to be honest I hated them. The problem was my miserable eyesight. If I looked through the compound scopes with my glasses on, then I had almost no field-of-view to work with. I could take my glasses off and still focus the scope, but any notes I took would be utterly unreadable. My attempt at a solution was to sort the flies into piles with my glasses off, then count the piles with my glasses on. Would have worked, except the Fly-Nap would wear off during the counting phase and my piles would start merging under their own power.
But Harvard employed a system in which carbon dioxide was continually bled into the pad under the compound scope. With that system, you can leave flies knocked out for literally hours, though some geneticists worry about ill effects to the flies from extreme exposure. I didn't ever take that long, but my sort-then-count scheme worked well.
I found a lot of appeal in the fly room. Because Drosophila had been worked on for nearly a century at that point, there were all sorts of nifty genetic tricks known. A lot of fly work requires less than your full brain, so you can spend the rest thinking over experiment designs or discussing science with your colleagues who are also sorting flies. It also helped that all of the scientists and techs in the Fly Room were very welcoming. So I really did seriously consider staying in Bill's lab.
One person who was very happy I didn't was my wife. She visited me exactly once in the Fly Room; the stench of fermenting bananas is something I can block out but it utterly revolted her. She also hated when I was collecting virgin flies, as I was going in three times a day for about two weeks straight on a very strict schedule; she complained that flies were running our lives.
Bill gave me an interesting rotation project. He had three or four position mutants that he proposed having me try to find modifiers. These mutations each display a different stable, reproducible pattern of coloration in their eyes; Bill was challenging me to find mutations which change those patterns.
Drosophila eyes are normally a red color. The first mutation found by Thomas Hunt Morgan was the white mutation, which erases this color. As an illustration of the fun twists which genetics can take, if you think that the white gene is responsible for making the responsible pigment, you'd unfortunately be wrong. The white gene is a transporter of pigment, a member of the ginormous ABC transporter family which includes the cystic fibrosis gene and exporters of drugs (both in patients and in producers). There are many families of transmembrane exporters, but the ABC group is probably the largest and most diverse. White is also a sex-linked gene in Drosophila, carried on the X. Alas, my nitpicking gene was activated today reading Siddhartha Mukherjee's excellent The Gene, which puts white on the Y.
Anyways, just because the white gene is normally on the X chromosome doesn't mean geneticists can't put it somewhere else. A wild-type white gene missing a full complement of transcriptional signals will not be transcribed. However, if installed on a transposon (aka "jumping gene") which hops around the genome, some of the resulting insertions will result in the white gene being successfully transcribed in the eye. By the correct set of crosses or other tricks, the transposon and its ability to hop (the transposase) are separable, so that the insertions are fixed in place. In most cases, the entire eye will turn red. But in position mutants, a reproducible pattern is formed in the eye.
If I remember correctly, I was given four different such position mutants, but to my embarrassment I can remember only three. I'll sketch them below, but here is the description. One was a P-element insertion which had been generated and published by Tulle Hazelrigg which resulted in only the bottom half of the eye being dark red; in young flies the top half would be white, ripening to a dull orange as the flies aged. Another created a tiny crescent of color in the upper part of the eye. But the one I found most striking was one which created a wedge of color pointing to a single line of colored facets crossing the eye.
Those facets, or ommatidia, are what make a compound eye compound. Each is a subassembly of photoreceptors. If you've seen insect vision at a zoo or museum (or on The Simpson's) depicted as each facet with a different image, that's not remotely like the truth. Each ommatidium is closer to one pixel, with different photoreceptors within the subassembly recording different wavelengths of light.
The most famous photoreceptor type is R7, which senses ultraviolet light. The great Seymour Benzer had previously developed a genetic mapping system for phage so precise he could map at nucleotide resolution. Looking for a new challenge, he decided to explore the genetic basis for fruit flies positive phototaxis for ultraviolet light. So he mutagenized flies and then had them pass through a series of Y-shaped tubes. Only one side of each Y was illuminated with UV light, so wild-type flies would always go that way, but any flies deficient for R7 would pick randomly. Using this approach, Benzer isolated sevenless (sev).
Sevenless became a paradigm for understanding cell fate decisions. One approach to further elucidating the genetics of this system was to isolate various additional mutants which interacted with sevenless, with such whimsical names as bride of sevenless (boss) and son of sevenless (sos). Because these circuits turned out to be biochemically related to key circuits involved in human cancer (sev is a receptor tyrosine kinase; sos is a nucleotide exchange factor for RAS), the sevenless genetic circuit has proven valuable for contributing to our understanding of a wide range of human cancers.
So my task was a similar idea, but applied to these position mutants. Obtain a large number of unmated ("virgin") females homozygous for the mutant in question. Females won't respond to male's mating approaches for a time after emerging from their pupal state, so during that window one can collect them. That was the procedure that my wife disliked due to insects controlling our schedule. Collect a similarly large number of homozygous white males, which is easier because you really don't care if they have mated. Mutagenize the males with gamma rays to create double-strand breaks, using a huge metal contraption that insured that nothing larger than a small bottle could ever be exposed to the gamma ray source. Now mate the flies and start looking through the offspring for alterations in the eye patterns.
Now, what I've described is a simple screen which will pick up dominant mutations. A quarter century of not thinking about the screen has erased my memory of whether I tried to cross the progeny with each other to look for recessive mutations (I think I did).
I do remember finding a great example of a Drosophila oddity: a gyandromorph. In humans, anatomical males are created by a gene on the Y-chromosome activating in testes tissue and then triggering the secretion of hormones into the bloodstream. Cells around the body see this signal, which synchronizes them to be male. A lack of this signal, and all cells progress down a female genetic program.
But in flies, each cell decides on its own. Rather than the presence of a Y, the determinant is the ratio of X chromosomes to autosomes. One X is male, two Xs are female. In most flies, every cell will have the same chromosome complement, so all of the fly's cells express the same gender. But, if a damaged X-chromosome (such as one zapped by a gamma ray) is present, then sometime after early mitoses in the embryo that second X can be lost. So now a subset of cells have one chromosome (male) and others two (female). In the case of the fly I found, one X probably dropped in the first mitosis, as it appeared be almost precisely half-and-half. The front of the fly showed several female-specific anatomical features, whereas the abdomen showed male-specific features. Other planes of symmetry (or asymmetry) are possible and seen.
I looked through a lot of offspring; I think the goal was either 5,000 or 10,000 offspring per cross. Or did I isolate 10,000 virgin females? Again, memory is failing me. I didn't find any stunning variants, but I do remember pulling a small number of candidates for modifiers. Then my rotation ended, and even if I had stayed it would have only been a side project at most.
Still, those position mutations are very interesting. Assuming that each faithfully represents the actual expression pattern of at least one eye-specific gene, why these patterns? Why does some fly gene express only in the lower (ventral) portion of the eye? Why would some gene shows that crazy wedge plus line pattern?
But perhaps more interesting would be if I had found modifiers, as these would potentially be the genes enforcing these rules of expression. While there was clearly leakiness over time, in the young flies the pattern was essentially binary; ommatidia were either red or white. Obtaining such sharpness of gene control is a marvel, so dissecting it would be fascinating.
It is worth comparing these against possible genomic approaches. Given current methodologies, it is not unreasonable to think that one could use various single cell transcriptomics approach to map out all the different expression patterns in a fly eye. The position mutants capture these in a striking visual way, but we have no means of knowing all the possible position mutants that have never been seen.
But finding the enforcers? That would likely be difficult or impossible from transcriptome data. Such tight patterns are most likely a combination of effects from multiple genes, creating a complicated circuit ANDs, ORs and NOTs. These interactions could be at the level of assembling transcription complexes, or activating them, or numerous other levers which eukaryotic cells possess for shaping gene expression. Genetics approaches are a proven route for identifying such interactions, particularly valuable since it is agnostic to the biochemical mechanism of control.
I haven't kept up with Drosophila genetics other than at a very cursory level. Perhaps these days one would screen a large RNAi or CRISPR collection to look for mutants, rather than gamma rays. Perhaps today I would have used a chemical mutagen, particularly now that it is so easy to determine the precise mutation using inexpensive whole genome sequencing. The technology can only get better, but the core strengths of Drosophila will always be there: fast generation time and the ability to run huge screens, so long as you can stand the smell of the Fly Room.
Posted by Keith Robison at 11:10 PM
Mike the Mad Biologist said...
Just one minor nitpick/quibble. Jim Ostell is still at NCBI and still a force there.
Keith Robison said...
Thanks - somewhere I picked up the misimpression he had retired.
Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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Fractional Chern insulators are fractional quantum Hall states realized in lattice models with full lattice translational symmetry in the absence of an external magnetic field. In fractional quantum Hall systems, pseudopotential Hamiltonians have been constructed for which the ideal ground states such as Laughlin states are exact ground states. In this work, we constructed pseudopotential Hamiltonians for the fractional Chern insulators by making use of the Wannier function representation. The physical interaction Hamiltonians can be expanded in pseudopotentials, from which one can analyze the preferred fractional quantum Hall states in the corresponding systems. The results of this analysis are compared with exact diagonalization. Our approach may be generalized to studying nonabelian fractional Chern insulator states and time-reversal invariant fractional topological insulators.


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Richard Gough: Global Dramaturgies
Photo courtesy of the artist.
Room #3416, GC CUNY, Third Floor
12:00pm Lecture
FREE + Open to public. First come, first served.
Join scholar, author, and editor Richard Gough as he explores and anticipates the future of global dramaturgy. Gough will discuss changes in international dramaturgical practice, why we should be interested in it, what new ways of research might look like, and what pitfalls might arise. Followed by a discussion with Peter Eckersall.
Performance Research resists disconnected, disembodied and disinterested forms of scholarship. Performance Research combines writings and works for the page in an interplay of analysis, anecdote, polemic, and criticism–interweaving the oblique with the conflicting, the pivotal with the resistant and the eclectic with the indispensable.
Richard Gough is Artistic Director of the Centre for Performance Research (CPR), Professor of Performance Research, Falmouth University, Fellow of IRC/IPC Freie Univeristat Berlin, and General Editor of Performance Research (The Journal of Performance Arts published bi-monthly by Routledge, Taylor & Francis) and Performance Books. He was founding President (1997-2001) of Performance Studies international (PSi) and he has curated and organized numerous conference and workshops over the last 40 years as well as directing and lecturing internationally.


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Home/Dnstyles/[Discount] Bruce Springsteen born to run cloth face mask
[Discount] Bruce Springsteen born to run cloth face mask
Duy Nam May 3, 2020
>> CLICK HERE TO BUY BRUCE SPRINGSTEEN BORN TO RUN CLOTH FACE MASK FROM DNSTYLES <<
The Invisible War Behind Closed Doors Inside Barracks David J. Gargiulo University of North Georgia Abstract During women/s occupation within the branches of armed services in the United States, soldiers (both men and women) are sexually assaulted and raped regardless of location, rank, sex, and branch. Most cases are not reported or looked over, but the ones that are looked into usually are not taken seriously or simply open-shut investigations. The Invisible War goes into detail on the few women where the cases were so severe that legal action was taken place to national government and allows you to see a portion of their lives after the incidents even after officials have said that they will look into the investigations and prevent rape occurrences from happening. Bruce Springsteen born to run Of all the women that are interviewed during this documentary, one man comes forward speaking about an occurrence that had happened to him showing that its not just men going after women, but also men targeting men. Even after congressional meetings, the numbers still kept climbing further questioning the United States government on how seriously these incidents are being taken.
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The Invisible War Behind Closed Doors Inside Barracks The movie starts with a couple of armed service commercials used inviting women to join the service and immediately goes into a few women talking about their rape such as Kori Cioca, Jessica Hinves, Robin LaFayette, Lt. Ariana Klay, and one man, Michael Matthews. The English Patient (1996) tells the story of a badly burned pilot, (Count Laszlo de Almásy) who is being taken cared of by a young war nurse (Hana) and experiences a series of flashbacks that reverts him back to a world of love, betrayal, and passion. Bruce Springsteen born to run Love is explicitly shown throughout the entire film and can be considered the backbone of the film. The story can be seen as a tragedy as was the story of the beloved doomed lovers Romeo and Juliet. The characters, plot, and the themes of the film The English Patient (1996) showcases the human nature of love. The plot of The English Patient (1996) can be seen as tragedy. The film takes place around the late 1930s and early 1940s (World War II). The opening scene is a plane being shot down in the middle of desert; a very badly burned victim is carried out of the wreckage who is surprisingly still alive.
What a nice mask!
The victim somehow ends up in the hands of armed British Forces. He does not have any recount of who he is but can speak fluent English. A war nurse that goes by the name of Hana, assumes responsibility for the burn victim and takes care of him in an abandoned building so he can reside in peace. They are later on joined by Kip, a Sikh sapper in the British Army who defuses bombs and has a love affair with Hana before leaving, and David Caravaggio, a Canadian Intelligence Corps operative who is questioned by Germans and had his thumbs cut of by a German interrogator. Throughout the film David Caravaggio questions the victim. Bruce Springsteen born to run A person gender or sexuality does not discriminate which person it belongs to but others discriminate against it. Gender has many inequalities that have been in the appearance for decades. Gender inequality is the unequal treatment of individuals based on their gender. In a work place there are numerous cases of gender inequality; gender plays a major role when it comes to the work force. Various studies show how there is a "gender pay gap," between men and women.
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After a 4-year-old took doll from store, video shows Phoenix police pulling a gun on parents
Thread starter imaginethat
FrostKing
Sabcat said:
Yup, cops. Gotta love em.
What's the solution?
There is a number of solutions.
The first one is to revise the thug cops' contracts with the clause that if they are involved in an incident that costs the city $1.00 in damages in a court case they will be terminated from the force and can not appeal the termination in any venue.
The second one is for the victim and other concerned people to picket the police station with placards saying that the cops are jackbooted assholes and stupid as dog shit.
I think in this particular case the people are suing the city for $10 million. I would be pissed off as a city taxpayer to have to foot part of that monetary award if the plaintiffs win.
The mayor and police chief have already said that the cops were wrong. If they testify in court the city will have to write a big check.
Phoenix Mayor Apologizes After Police Draw Guns on Family Over Report of Stolen Doll
"The mayor, Kate Gallego, said in a statement that she was "sick" over what she had seen in the videos.
"It was completely inappropriate and clearly unprofessional," she said. "There is no situation in which this behavior is ever close to acceptable. As a mother myself, seeing these children placed in such a terrifying situation is beyond upsetting."
Phoenix Police Chief Jeri Williams addresses excessive use of force and shoplifting video gone viral
VIDEO: Phoenix's police chief apologizes to family, community over incident
Likes: Clara007
imaginethat said:
It's beyond not acceptable,
The two officers pointed their weapons at the visibly pregnant 24-year-old Harper and her children, the video shows and the claim stated.
"The first officer grabbed the mother and the baby around both of their necks, and tried to take the baby out of the mother's hand," the claim alleged. "He told her to put the baby on the ground, which she was unwilling to do because the baby could not walk, and the ground consisted of hot pavement."
The officer tried to rip Harper's youngest child from her arms, the claim stated. Eventually he threw Harper, who had handed the children to a bystander, into the police car face first and then handcuffed her.
If you notice, the media is always eager to expose the victims or suspects life history from the minute they were born in cop brutality cases. They will never reveal any information about the thug cops until they absolutely have to, and them it is very skimpy. I believe that in most of these incidents the cops are former military personnel who are in the land of complete psycho. They think that they are still in a war zone. Combat veterans should never be hired as city cops. They are dangerous animals and should be regarded as such by everyone at all times in every circumstance.
Likes: imaginethat
imaginethat
FrostKing said:
Combat veterans should never be hired as city cops.
Amen to that. Our professional military ensures we'll always have psycho cops. Our non-stop wars pollute the soul of our nation.
Remember the right freaking out over Hillary "WWIII" Clinton. Under Trump, the defense budget is headed for the trillion dollar mark.
Promises kept. Yeah.
This is one issue that won't have a happy ending.
Brown Township, Ohio
Combat Vets should best serve in the Electro-Mechanical industry where they make big bucks and retire early.
Clara007
Kate Gallego is new to the job and she's doing great. There was a time when our Phoenix mayor would just blow this off---NOT KATE. We'll be watching the evening news tonight.
The whole thing is appalling.
Clara007 said:
I am hearing news reports that two women were involved in some event at a Dollar Store parking lot, one was arrested at scene and the second drove away and was stopped at an apartment complex where the video was done. That "fleeing" suspect in a vehicle might be a partial explanation for the strange or extreme police response. It is likely that the Spirit of Joe Arpaio continues to be a factor as well.
Likes: leekohler2 and Clara007
Beware of watermelons
Send 'em to the big house. Make damned sure they never again work as a cop
That's addressing the symptom not the problem.
Beats doing nothing.
leekohler2 said:
In Trump's America, its just fine. I don't really know what it is going to take for people to wake up. So many things I thought would be unacceptable no one seems to care about. Have we had one right-winger in here condemn this? Nope. That should speak volumes.
But, I have said this before, the flip side of this is that the right has shown us their true face in no uncertain terms. The karma train is coming for them, and I think they know it. That's why they're upping their game before 2020.
This is either naive or blindly partisan implying that this has anything to do w/ the current administration. This has been a growing ongoing problem for decades. Mostly has to do w/ the militarization of the police force that goes hand in had w/ the war on drugs.
It is this sort of mindset that does not allow the problem to be addressed. The same as when race it is attempted to be interjected as the core of the issue.
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Phillip Jensen has made a significant contribution to Australian Evangelicalism over many decades. Yesterday he wrote a Facebook post about Hell (quoted in full below) and a friend shared it. As I respect both my friend and Phillip (who I met about a decade ago), I thought I'd take the time to engage with him here.
Its very existence reassures us of ultimate justice. Where else can the victims of the Holocaust find justice? But justice is little comfort when we consider hell's horror.
Yes… but I think it does so in a different way than you think. It seems to me that justice is about righting wrongs, and that while punishment can be involved, punishment of a perpetrator alone cannot heal the victim, cannot restore the relationship to how God intended all relationships to be: a reflection of the relationship within the Trinity. That requires reconciliation of the estranged parties, which requires repentance and (self-sacrificial) forgiveness. All of which is only possible when the Holy Spirit works within a situation.
Hell is such a horrible concept that sensitive souls want to recoil from even considering it. Denying its existence can even be called a godly heresy. Godly – in that God does not enjoy the death of a sinner and nor should we (Ezekiel 18:23,32; 33:11, 1 Timothy 2:4, 2 Peter 3:9); but – a heresy none the less because the scriptures teach the reality of judgement and hell (Matthew 7:13, 21-23; 10:28).
I agree that it's not a pleasant topic―indeed I have friends who have been deeply scarred by having certain interpretations of Hell forced upon them as children (some to the extent that they can no longer trust God). Personally I don't deny God's judgement and Hell's existence (although we differ on the nature, purpose, and duration), and I do consider both almost every day (which isn't an exaggeration).
However, I don't think everyone who denies Hell's existence is just being "sensitive", I know some people who do so for theological and philosophical reasons―although I think that unfortunately puts them outside orthodox Christianity, which means it is technically heresy.
I agree that God doesn't enjoy the death of anyone and that we shouldn't either.
Much of what horrifies people about hell is the vivid and imaginative presentation of it by preachers, artists and writers. When confronted by scary pictures, some people close their eyes while others bravely make fun and laugh at them. So we have the Christians who cannot so much as think of hell and the non-Christian who will parody the whole notion portraying Satan with horns and tail, pitchfork and opera cape, or boasting, with more bravado than sense, of sharing a beer and a joke with all their mates down there.
I agree, although to be fair, Christians often haven't helped the situation by grossly misrepresenting the topic.
Both responses make speaking on hell difficult. On the one hand the preacher is accused of insensitively using manipulative scare tactics and on the other hand he is ridiculed for believing in childish ghost stories. But it is our Lord Jesus himself who used hell in his preaching, so we must not – and cannot – leave it out of our declaration of the whole counsel of God.
I agree, although I think He was often using it differently than modern preachers.
So what do we know about hell? The Bible itself spends very little time describing or even mentioning hell. The word only occurs 12 times in the Bible, all in the New Testament, all but once on the lips of Jesus. Based on usage of the word 'hell', there is only one hell fire preacher in the Bible – and that is our Lord Jesus Christ.
I agree hell isn't the focus of the Bible but it depends a bit on how you define it… For example, passages that describe future punishment are often interpreted as speaking about hell.
The word itself referred to the valley of the sons of Hinnom, close to and outside Jerusalem. The valley had been used for human sacrifices to Molech but was intentionally 'defiled' in Josiah's reforms (2 Kings 23:10, 2 Chronicles 28:3, 33:6). The prophets (Isaiah 30:31-33, Jeremiah 7:31, 19:5-6, 32:35) spoke of it as the valley of slaughter and of its fire and vermin as the final end place and destruction of the wicked.
The descriptions of hell are usually minimal but involve fire, corpses and vermin (Isaiah 66: 24, Mark 9:43, 48, Matthew 18:8 James 3:6). Other parts of the New Testament speak of the final state of judgement in terms of outer darkness, weeping and gnashing teeth, destruction, and second death. However, eternal fire is an image of God's prepared punishment for the devil and his angels, to which sinful humans can be cast (Matthew 25:41, Revelation 14:10, 20:10).
I agree, except I don't think the Bible says it's the final state.
While the word 'hell and any descriptions of it are used sparingly in the Bible, retributive punishment is widely taught and illustrated. Such punishment is not limited to this world and lifetime only; for both judgement after death and life after death are clearly taught in scripture. (Isaiah 66:22-24, Hebrews 9:26-28). Indeed the very concept of "the resurrection" is one of judgement as well as eternal life beyond the grave (Matthew 10:28, Luke 14:14, John 5:28-29, Acts 17:31).
I agree that judgment and punishment isn't limited to this age but that it also occurs in the next. However, I think the type of punishment isn't as clear as you think. There are certainly passages that sound retributive, and may well be. However, just because punishment is retributive doesn't mean it can't also serve a purpose. For example, Sodom and Gomorrah get burned to the ground but later we discover God restoring them.
A similar destruction followed by restoration occurs with Egypt, Israel's architype enemy, in Isaiah 19. Likewise with the Israel in Romans 11―indeed I think Paul goes as far as saying that it happens with everyone.
So then, as through one trespass [Adam's] there is condemnation for everyone, so also through one righteous act [Jesus'] there is life-giving justification for everyone.
Both this life and judgement are talked of as 'eternal' (Matthew 25:46).
The highlight of the age to come will be my long service leave and lowlight of the age to come will be my sick leave.
I look at this in more detail in Is Aionios Eternal? and Pruning the Flock?.
The permanence of this judgement is emphasized in Jesus' parable (Luke 16:19-31), as well as Paul's language of "eternal destruction, away from the presence of the Lord and from the glory of his might" (2 Thessalonians 1:9).
The parable is more about Jesus and his mission to be the Israel that the Pharisees had failed to be, rather than a discourse on the afterlife.
Furthermore, there's evidence it's probably a "subversion" of a parable the Pharisees would've known e.g. there's an Egyptian parallel, seven Jewish ones, and one from Lucian (Greco‐Roman) (see Bauckhman, The Fate of the Dead, chapter 4). There are other considerations too e.g. it's talking about Hades (which comes to an end in Revelation) before Christ had died and visited it―unlocking it's gates and bridging it's chasm (I really should dedicate an entire post about it one day).
This morning I posted a post dedicated to 2 Thessalonians 1:9. I don't think it gives much support to your position, partly because it's relying on the word mistranslated as "eternal".
Jesus teaches us about hell to warn us of behaviour that would take us there. In Matthew 5:22 he speaks of hating and despising our brother in such fashion as to be liable to the hell of fire. And in Matthew 5:29, 18:9 and Mark 9:43-47, he portrays the horror of hell in such terms that it would be better to lose an eye or a hand than ever to be thrown there. In Matthew 10:28 and Luke 12:5 he warns us to be more fearful of the one who can destroy both body and soul in hell rather than the one who can only kill the body.
I agree, although I think we need to be careful not to take Matthew 10:28 out of it's context, which is encouraging the disciples―that their persecution isn't unexpected (v.22-25), that God cares deeply for them.
"Therefore, don't be afraid of them, since there is nothing covered that won't be uncovered and nothing hidden that won't be made known. What I tell you in the dark, speak in the light. What you hear in a whisper, proclaim on the housetops. Don't fear those who kill the body but are not able to kill the soul; rather, fear Him who is able to destroy both soul and body in hell. Aren't two sparrows sold for a penny? Yet not one of them falls to the ground without your Father's consent. But even the hairs of your head have all been counted.
Whatever we do or do not know about the details of hell, it is clear from Jesus' teaching that it is so terrible and terrifying that we should do all in our power to avoid it.
Our hatred of hell is but a pale reflection of God's detestation of its terrors. It is why he responded to Amos' prayers by holding back the judgement that was coming on Israel (Amos 7:2-6) and why his heart recoiled within him when faced with destroying Israel (Hosea 11:8f). It is this compassion of God that even now means he patiently endures sinfulness to give time and opportunity for us to repent (Romans 2:4f, 2 Peter 3:9f). And even more, it is God's compassionate desire that none should perish, which moved him to give his only Son that we should not perish at all but have eternal life (John 3:16); and it is because of his Son's similar compassionate desire that Christ Jesus gave himself as a ransom for all (1 Timothy 2:4-6).
I agree, although I would suggest that the passages you quote here (as well as those in your 3rd paragraph) should prompt us to reconsider the nature, purpose, and duration of hell. That perhaps it isn't solely retributive, that God has bigger plans, a higher telos, for each and every being He has created in His image.
I would also suggest that "God's detestation of [Hell's] terrors", as well as His compassion, motivates Him to make Hell cease. I believe this is well within the ability of an all-powerful, all-knowing, infinitely resourceful and patient God. Indeed I think He promises to do so. I don't expect you to be necessarily convinced by this response but I would seriously challenge you to read the Four Views on Hell: Second Edition, which has been recently published by one of the largest Evangelical publishers, Zondervan. It makes a strong case for Eternal Conscious Torment, Conditionalism, and Universalism all being legitimate, biblical, Evangelical positions.
Hell is a horrible topic but we must not avoid thinking about it or preaching it, for it is the basis of seeing not only the ultimate justice of God but more importantly the greatness of our God's compassion and saving work in Jesus.
I agree, although I think hell isn't the entire picture of "ultimate justice".
There is no joy in hell but that is why there is such joy in heaven over every sinner that repents (Luke 15).


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Makers, People July 22, 2015
Chambers, People June 23, 2015
Design, Makers, People June 2, 2015
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Chambers February 21, 2015
Chambers January 10, 2015
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