text:
package org.hammerlab.guacamole.windowing

import org.hammerlab.genomics.loci.iterator.LociIterator
import org.hammerlab.genomics.reference.{ContigName, Interval, Locus, Region}
import org.hammerlab.guacamole.readsets.PerSample

import scala.collection.mutable

/**
 * Suppose we have a set of loci on a given contig and some objects that are mapped to that contig, and at each locus we
 * want to look at the regions that overlap a window of a certain number of bases surrounding that locus. This class
 * implements this "sliding window" functionality.
 *
 * After instantiating this class, call [[setCurrentLocus]] repeatedly for each locus being considered. After calling
 * this method, the [[currentRegions]] property will contain the objects that overlap the current locus.
 *s
 * To enable an efficient implementation, we require that both the sequence of loci to be considered and the iterator
 * of objects are sorted.
 *
 * @param halfWindowSize Number of nucleotide bases to either side of the specified locus to provide regions for. For
 *                       example, if [[halfWindowSize]]=5, and our [[currentLocus]]=100, then [[currentRegions]] will
 *                       include regions that map to anywhere between 95 and 105, inclusive. Set to 0 to consider only
 *                       regions that overlap the exact locus being considered, with no surrounding window.
 * @param rawSortedRegions Iterator of regions, sorted by the aligned start locus.
 */
case class SlidingWindow[R <: Region](contigName: ContigName,
                                      halfWindowSize: Int,
                                      rawSortedRegions: Iterator[R]) {
  /** The locus currently under consideration. */
  var currentLocus = -1L
  /** The new regions that were added to currentRegions as a result of the most recent call to setCurrentLocus. */
  var newRegions: Seq[R] = Seq.empty

  private var mostRecentRegionStart: Long = 0
  private val sortedRegions: BufferedIterator[R] = rawSortedRegions.map(region => {
    require(region.contigName == contigName, "Regions must have the same reference name")
    require(region.start >= mostRecentRegionStart, "Regions must be sorted by start locus")
    mostRecentRegionStart = region.start

    region
  }).buffered

  private val currentRegionsPriorityQueue = new mutable.PriorityQueue[R]()(Interval.orderByEndDesc)

  /** The regions that overlap the window surrounding [[currentLocus]]. */
  def currentRegions(): Vector[R] = {
    currentRegionsPriorityQueue.toVector
  }

  /**
   * Advance to the specified locus, which must be greater than the current locus. After calling this, the
   * [[currentRegions]] method will give the overlapping regions at the new locus.
   *
   * @param locus Locus to advance to.
   * @return The *new regions* that were added as a result of this call. Note that this is not the full set of regions
   *         in the window: you must examine [[currentRegions]] for that.
   */
  def setCurrentLocus(locus: Locus): Vector[R] = {
    assume(locus >= currentLocus, "Pileup window can only move forward in locus")
    currentLocus = locus

    // Remove regions that are no longer in the window.
    // Note that the end of a region is exclusive, so e.g. if halfWindowSize=0 and head.end=locus, we do want to drop
    // that read.
    while (currentRegionsPriorityQueue.nonEmpty && currentRegionsPriorityQueue.head.end <= locus - halfWindowSize) {
      val dropped = currentRegionsPriorityQueue.dequeue()
      assert(!dropped.overlapsLocus(locus, halfWindowSize))
    }

    newRegions = if (sortedRegions.isEmpty) {
      Seq.empty
    } else {
      // Build up a list of new regions that are now in the window.
      // Note that the start of a region is inclusive, so e.g. if halfWindowSize=0 and head.start=locus we want to
      // include it.
      val newRegionsBuilder = mutable.ArrayBuffer.newBuilder[R]
      while (sortedRegions.nonEmpty && sortedRegions.head.start <= locus + halfWindowSize) {
        val region = sortedRegions.next()
        if (region.overlapsLocus(locus, halfWindowSize)) newRegionsBuilder += region
      }
      newRegionsBuilder.result
    }
    currentRegionsPriorityQueue.enqueue(newRegions: _*)
    newRegions.toVector // We return the newly added regions.
  }

  /**
   * Find the next locus for which calling setCurrentLocus(locus) would result in a non-empty set of regions in
   * currentRegions.
   *
   * @return Some(locus) if such a locus exists, otherwise None
   */
  def nextLocusWithRegions(): Option[Long] = {
    if (currentRegionsPriorityQueue.exists(_.overlapsLocus(currentLocus + 1, halfWindowSize))) {
      Some(currentLocus + 1)
    } else if (sortedRegions.hasNext) {
      val result = math.max(0, sortedRegions.head.start - halfWindowSize)
      assert(result > currentLocus)
      Some(result)
    } else {
      None
    }
  }
}

object SlidingWindow {
  /**
   * Advance one or more sliding windows to the next locus in an iterator, optionally skipping loci for which no windows
   * have regions.
   *
   * If this function returns Some(locus), then all the windows are now positioned at locus. If it returns None, then
   * there are no more loci to process (we have reached the end of the loci iterator), and the positions of the sliding
   * windows are undefined.
   *
   * This function takes an iterator of loci instead of a single locus to enable it to efficiently skip entire ranges of
   * loci when skipEmpty=true.
   *
   * @param windows SlidingWindow instances to be advanced
   * @param loci iterator over loci. This function will advance the iterator at least once, and possibly many times
   *             if skipEmpty is true.
   * @param skipEmpty whether to skip over loci for which no window has any regions
   * @return Some(locus) if there was another locus left to process, otherwise None
   */
  def advanceMultipleWindows[R <: Region](windows: PerSample[SlidingWindow[R]],
                                          loci: LociIterator,
                                          skipEmpty: Boolean = true): Option[Long] = {
    if (skipEmpty) {
      while (loci.hasNext) {
        val nextNonEmptyLocus = windows.flatMap(_.nextLocusWithRegions).reduceOption(_ min _)
        if (nextNonEmptyLocus.isEmpty) {
          // Our windows are out of regions. We're done.
          return None
        } else if (nextNonEmptyLocus.get <= loci.head) {
          // The next locus with regions is at or before the next locus in the iterator.
          // We advance to the next locus in the iterator, and check if the resulting windows are all empty.
          val nextLocus = loci.next()
          windows.foreach(_.setCurrentLocus(nextLocus))

          // Windows may still be empty here, because the next locus with regions may have been before the next locus,
          // and now we just fast-forwarded past the regions into an empty area of the genome.
          // If any window is nonempty, we're done. If not, we continue looping.
          if (windows.exists(_.currentRegions.nonEmpty)) {
            return Some(nextLocus)
          }
        } else {
          // The next locus with regions is beyond the next locus in the iterator.
          // We skip the iterator forward so in the next iteration of the loop, we'll be at the locus with regions.
          loci.skipTo(nextNonEmptyLocus.get)
        }
      }
      // No more loci remaining in the iterator. We're done.
      None
    } else if (loci.hasNext) {
      // Not skipping empty, and we have another locus in the iterator to go to.
      val nextLocus = loci.next()
      windows.foreach(_.setCurrentLocus(nextLocus))
      Some(nextLocus)
    } else {
      // We are out of loci.
      None
    }
  }
}

redpajama_set_name: RedPajamaGithub


East Tennessee (McMinn County) miniature chest of drawers, walnut primary, pine secondary. Plain slightly overhanging top over one full overhanging dovetailed drawer above three full graduated dovetailed drawers. Turned and carved pilasters with inlaid hearts at the top and inlaid diamonds at the base, paneled sides, rounded skirt and turned incised feet. 14 3/4" H x 15" W x 9 3/4" D. 12 lbs. Circa 1830. Provenance: Private Knoxville, TN collection. CONDITION: Older surface. Knobs on lower three drawers not original. Lower right diamond inlay damaged/missing. Crack to skirt that extends horizontally.


BEGINNER MAKEUP TUTORIAL 100% Drugstore + Intermediate Tips!
Emily Marie Ricketts: So I'm 25 and just getting into the a while makeup routine. This video was great!! Thanks Muchly ☺ I'm from Newfoundland Canada!!
Teagan Gratte: I know u uploaded this vid ages ago and it is hard for u to answer every comment but I am a teen and I have acne issues so what products are safest to use and I am also literally only just starting to buy and use makeup products so yeh!!
Azmath jaffery: Hey I ha e dri skin so would that foundation be could for my skin and would I need to use primer ??
DIY Makeup Hacks: You are very beautiful, no makeup will spoil it!


That Combustion change is really bad. =\\ Do they want mages to all play Frost?
Dang that Dark shaman cosmetic set!
Blizzard, you killed dk's. Gratz !
took them long enough too change it.
Nice, warrior DoT buff! And also Arms got a huge buff by that additional 110% weapon dmg!
How defuq can they nerf combust so much?
OMG people calm down, this is just wave one of the buffs\/nerfs that Ghostcrawler has been warning about for awhile now.. the tuning patches will roll around to your class and what not soon as they can... jeez..
Also, I knew mages would QQ soon as some kind of nerf would happen to them. Too funny.
This is a bit disappointing. Multi-dotting to cause more procs of shooting stars is one of our major sources of dps. I don't think this will be game changing, but we could experience slightly lower overall dps. If they wanted to deal with the issue of overlapping procs, I wish they would go to a counter system as others have suggested; instead of lowering the number of procs.
Are you seriously complaining DKs didn't get a buff? They're OP as it is; maybe when they become a ^&*!tier class like the rest of us you'll get your damn buff.
Hey, I see that received a change. That means that is now .
That's a splendid set. I'm not much of a dress guy though. Need some plate legs to match. Would like to see a long loin cloth to make a decent barbarian set.
I like that cosmetic set, but worried it may be a cash shop item.
Frost needs to be nerfed i admit that.


U.S. Customs and Border Protection (CBP), welcomes Fortigo Freight Services Inc. as a certified partner in the Customs-Trade Partnership Against Terrorism (C-TPAT) program.
CBP created the C-TPAT validation process to ensure that the security measures declared in a participant's C-TPAT security profile are effective. The Customs-Trade Partnership Against Terrorism (C-TPAT) is a voluntary supply chain security program led by U.S. Customs and Border Protection (CBP) and focuses on improving the security of private companies' supply chains with respect to terrorism.
The program was launched in November 2001 with seven initial participants, all large U.S. companies. As of April 2005, there were over 9000 companies participating, according to Secretary of the Department of Homeland Security Michael Chertoff.
Congratulation to all of the Fortigo staff, drivers and Owner Operators for a job well done!
© 2019 Fortigo Freight Services Inc.


text:
Has Tom Brady Lost Hope In The Offense?
Posted on December 3, 2019 December 2, 2019 by Steve Atkinson
Tom has a right to be frustrated
We are now in December and still haven't seen this offense at its full potential. Between the turnover at receiver, rookies not connecting with Tom Brady, and Dorsett and Sanu nowhere to be found it is very frustrating. Brady has come to the realization that there's been inconsistencies this season on the offensive side of the ball. In Brady's entire 20 year career this is the worst offense he's had since 2006. Brady used to turn an average receiver into a decent player. This season Brady only has Edelman Harry and Sanu got to this team late in the season and now can't adjust. Rookie Jakobi Meyers also can't get on the same page with Brady which isn't a good sign when there are six weeks left in the season.
There's no trust between Brady and his receivers except Edelman
The ones that complain that Brady shows emotion during the games because his receivers aren't on the same page need to give him a break. Brady has been on this team for two decades and has taken a pay cut after pay cut so they can use the money elsewhere. It's very frustrating when you draft a receiver in the first round and he misses half the season then comes back and isn't 100%. He knows this team's potential and they aren't living up to it. He's had no drop off in his physical ability to get the ball to the receiver. Sometimes he makes a bad decision but most of the time its guys running the wrong route or not being on the same page with the quarterback.
The Patriots had Edelman, Antonio Brown, and Josh Gordon at one point in this season. However, the only reliable one is Edelman when it comes down to it. Gordon had some discipline issues, and Brown doesn't know how to put down his phone. So now Brady is left with Edelman, who's double covered and a bunch of guys who can't get on the same page with him. But we just expect Brady to sit back and watch him not care? This could be his last season as his contract is up.
Brady is not all of the problems
Are some of the issues Brady's fault too? Yes of course, but he's not majority of the problem. The majority are these young guys not getting it, and the veterans Sanu and Dorsett are nowhere to be found. Has Brady given up on this offense? If he has he'll never admit it publicly, but he does realize they aren't as good as they have been in years past. I haven't even touched on Benjamin Watson, who is a good blocker but that's it. And Matt Lacosse is average at best.
Posted In NFL, PatriotsTagged In antonio brown, Benjamin Watson, Jakobi Meyers, Josh Gordon, Julian Edelman, Matt LaCosse, Mohamed Sanu, N'Keal Harry, NFL, Patriots, Phillip Dorsett, Tom Brady
Heat-Celtics Preview
Bruins Recap and Week Ahead Dec 2nd-Dec 7th

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: How to pass onClick funtion into a span created using string literals? I have an HTML object created using string literals and used  Dangerously Set HTML. Basically, I just had to create span and pass onClick while creating the string literal but when I pass the function which is bound in the constructor. later I get the error that this is not a function. How can I pass a function in onClick while creating the HTML object using string literals in react?
this HTML is set dangerously in render().
var html=`<span onClick="myFunc()">${text}</span>`;

A: this just a string, you can't have eventListerner on it.
Or declare a DOM element like this
var MySpan = Document.createElement('span');
MySpan.textContent = text;
MySpan.onclick = myFunc;

//....

function myFunc() {
  alert('span clicked !');
}

A: you can do like this: var html = {text}.
Now the 'html' can be sue as pure component in he mail component to render in DOM but here this.myFunc is wrong because pure component will not carry any scope by itself , ou have to pass the function as prop or use HOC for that.
And for more clearity kindly gothrough this pure component documentation of react :react pure component

redpajama_set_name: RedPajamaStackExchange


Exp Dermatol. 2014 Jun;23(6):391-2. doi: 10.1111/exd.12386.
Shedding new light on the role of the sunshine vitamin D for skin health: the lncRNA-skin cancer connection.
Section of Endocrinology, Nutrition, and Diabetes, Department of Medicine, Vitamin D, Skin and Bone Research Laboratory, Boston University Medical Center, Boston, MA, USA.
Throughout evolution, vertebrates including humans have depended on the sunshine vitamin D for their calcified skeletons. As our hunter gatherer forefathers ventured from the equator, their skin tone became much lighter in order to permit an adequate amount of ultraviolet B radiation to enter the skin to produce the vitally important vitamin D. Although sensible sun exposure does not significantly increase risk of skin cancer, it has remained a mystery as to why. Jiang and Bikle in their viewpoint provide a novel insight as to how Mother Nature was able to balance the need for receiving adequate sun exposure to produce vitamin D while limiting damage caused by the DNA absorbing the ultraviolet B radiation. Long non-coding RNAs which are plentiful in cells have a dual personality. Some enhance malignancy, while others act as tumor suppressors. Jiang and Bikle provide compelling evidence that these long non-coding RNAs in skin cells are responsive to 1,25-dihydroxyvitamin D3 by decreasing their carcinogenic activity while enhancing their tumor suppression function presumably as a strategy for reducing ultraviolet-induced non-melanoma skin cancer. Mother Nature got it right. Sensible sun exposure is important for maintaining an adequate vitamin D status. Once formed in the skin, vitamin D can exit into the circulation to carry out its physiologic functions on calcium and bone metabolism. Some vitamin D however remains in the skin and is activated to interact with its vitamin D receptor to control cell proliferation using a variety of strategies including interacting with long non-coding RNAs to reduce risk of photocarcinogenesis.


text:
Community Day School returns Jewish to its name
The Community Day School in Metairie has Jewish in its name once again.
The school's board voted to change the school's name in January. Originally the New Orleans Jewish Day School, the elementary school became Community Day School in September 2012 in an effort to broaden its appeal to the Reform, unaffiliated and intermarried communities, as well as non-Jewish families.
Head of School Sharon Pollin said the vote to become Jewish Community Day School "came from a desire that our school name be in full alignment with our mission and vision, and to ensure that all recognize who we are: a school dedicated to academic excellence, a strong Jewish foundation, and embracing the entire community."
Pollin became the head of school this past summer.
According to the mission statement, the school is "grounded in Jewish tradition, fostering spirituality (emunah), dedication to repair our world (tikun olam) and commitment to the entire Jewish people (klal Yisrael)." It is also a place "where families of all backgrounds are welcomed and children are prepared to be engaged compassionate leaders."
The school was founded in 1996 to give New Orleans a community Jewish school.
The school had grown to having Kindergarten to eighth grade in 2005, then Katrina struck after the first class of eighth graders graduated. The school remained closed for a year following the flood, then reopened without the middle school, having classes through fifth grade. Since reopening, the school has been working to rebuild enrollment.
There will be open houses on Feb. 4 at 9 a.m. and Feb. 7 at 2 p.m.


In order to comply with the CDG regulations (ADR), all companies involved in the movement of dangerous goods by road and that fall within the scope of ADR must have an appointed DGSA to advise on correct procedures.
EP Training has joined together with Cargo Training International, Training Team and Peter East Associates to provide the best possible DGSA course available.
Courses are run from Heathrow or Manchester. The course is 5 days in duration.
Courses are run to coincide with SQA examinations. It is an open book examination. 3 examinations must be sat and passed in order to gain this qualification.
The DGSA certificate last 5 years. The price (£1,500) includes tuition fees, VAT, permitted books and exam entry.
Any individual or company that transports dangerous goods, by law, must appoint a Dangerous Goods Safety Advisor (DGSA).
EP Training employ DGSA consultants who are available to assist companies in meeting their dangerous goods transportation requirements and who have many years DGSA experience.
If you need a DGSA, why not call the experts at EP Training.


text:
New data on the capital maintenance backlog: a special blog for governors
Investment in NHS capital funding is critical to safety, care quality and efficient use of NHS facilities. This has become increasingly clear during the pandemic when trusts with old and outdated estates and equipment found it more difficult to reconfigure old sites to accommodate social distancing and infection, prevention and control.
Yet the latest release of the estates return information collection (ERIC) data from NHS Digital shows there has been a substantial deterioration in the NHS estate. Covering 2019/20, the figures give us the most accurate picture of capital investment across the service, highlighting the tremendous pressure facing the provider sector's infrastructure.
Cash injection
Trusts began the 2019/20 financial year having been asked by NHS England and NHS Improvement to scale back their capital spending plans.
Their initial assumptions, driven by an increasingly urgent need to carry out essential maintenance and repair works, would have risked exceeding the overall spending provided for under the Department of Health and Social Care's capital departmental expenditure limit (CDEL).
Later that year, an additional welcome £1bn was added into the CDEL to boost NHS capital spend, allowing existing upgrades to proceed and tackling the most vital infrastructure projects.
However, the ERIC figures show that even with this additional capital injection, trusts' estates have still deteriorated significantly.
The maintenance backlog
The cost of bringing deteriorating assets back to a suitable working condition – known as the maintenance backlog – continues to rise. In 2019/20 the backlog was £9bn. This represents a 40% increase from the 2018/19 figure which stood at £6.46bn, and double the level seen five years ago.
Moreover, over half of the total outstanding capital maintenance is constituted as 'high' or 'significant risk'. (as Fig. 1 shows).
These figures point towards a clear escalation of risk which is jeopardising patient safety. In 2019/20, the number of clinical service incidents rose by 23% compared to 2018/19. Clinical service incidents caused by estates and infrastructure failure have risen in each of the past three years. Indeed, 45% of trust leaders surveyed by NHS Providers last year said their estate was in poor or very poor condition.
Why is this backlog figure so high? The data shows that parts of the NHS estate are deteriorating faster than trusts can invest to maintain it. In 2019/20, while £516m was spent by trusts on addressing these urgent maintenance works, the total backlog grew by five times this amount (as fig. 2 highlights).
Looking to the future
In 2021/22, the NHS capital budget has been increased to begin work on new hospital building, hospital upgrades, and to replace old diagnostic equipment and to make further progress on mental health inpatient facilities. This will result in many outdated and inadequate facilities being replaced and will reduce the backlog for trusts that receive funding.
Yet, while this is welcome, it is clear that the backlog is a systemic problem that requires a strategic response with sufficient funding to upgrade facilities across ambulance, community and mental health settings as well as further investment for acute hospitals. The growth of the maintenance backlog reaffirms the need to create a capital allocation system that recognises that trusts need to be able to access capital and have the freedom to spend it in a timely way.
It will always be appropriate for strategic projects to be signed off nationally, and for systems to collectively make decisions about capital works large enough to affect systemwide plans and budgeting. But individual organisations should have delegated authority to proceed with backlog maintenance and other small-scale works: where they do not have this freedom, investment will be delayed unnecessarily, to the detriment of efficiency, productivity, and patient safety.
The condition of the NHS estate has made responding to the COVID-19 pandemic more difficult. Trusts operating with old estates have managed under incredibly challenging circumstances to reconfigure their facilities to ensure adherence to infection control measures – but trusts with older estates report it has been more challenging to scale up capacity and convert facilities.
For governors
It is clear that trusts will need to spend more to address urgent repairs. The outstanding maintenance costs will continue to rise - heightening the risk to patient safety - unless the eradication of the backlog is prioritised. This will require a major increase in the amount of capital available to all trust types, dedicated to maintenance, repair and replacement of ageing facilities.
It will therefore be important to ensure you use your holding to account duty to gain assurance from non-executive directors (NEDs) about the impact the maintenance backlog has on your trust's ability to transform and improve services. You could also explore in your questioning with NEDs the degree of risk these outstanding repairs present to patient care.
The design and upkeep of buildings used across all parts of the provider sector has a material impact on patient care. The maintenance backlog ultimately presents a risk to the ability for trust leaders to discharge their duties and ensure patient safety standards across their estates.
A pragmatic approach required for NHS funding
Chris Hopson calls for a pragmatic approach to NHS funding so it can carry on delivering the care the country needs.
Anna Calderbank Senior Development Programmes Coordinator anna.calderbank@nhsproviders.org


text:
using System;
using System.Net;
using System.Windows;
using System.Windows.Controls;
using System.Windows.Documents;
using System.Windows.Ink;
using System.Windows.Input;
using System.Windows.Media;
using System.Windows.Media.Animation;
using System.Windows.Shapes;
using Microsoft.Phone.Info;

namespace WP7GapClassLib.PhoneGap.Commands
{
    public class Device : BaseCommand
    {
        public string Get()
        {
            /*
            object id;
            string uuid = "???";

            UserExtendedProperties.TryGetValue("ANID", out id);

            if(id != null)
            {
                uuid = id.ToString().Substring(2, 32);
            }
            */

            //string platform = Environment.OSVersion.Platform.ToString();
            //string version = Environment.OSVersion.Version.ToString();
            //string name = DeviceStatus.DeviceName;
            //string phonegap = "1.0";

            return "";
        }

        public string name
        {
            get
            {
                return DeviceStatus.DeviceName;
            }
        }

        public string phonegap
        {
            get
            {
                // TODO: should be able to dynamically read the PhoneGap version from somewhere...
                return "1.0";
            }
        }

        public string platform
        {
            get
            {
                return Environment.OSVersion.Platform.ToString();
            }
        }

        public string uuid
        {
            get
            {
                return getUuid();
            }
        }

        public string version
        {
            get
            {
                return Environment.OSVersion.Version.ToString();
            }
        }

        private string getUuid()
        {
            object id;
            UserExtendedProperties.TryGetValue("ANID", out id);

            if (id != null)
            {
                return id.ToString().Substring(2, 32);
            }
            else
            {
                return "";
            }

        }

    }
}


text:
Phases of the Audit Process
By Chad Buleen Updated February 04, 2019
How to Obtain a Copy of a 501(c)(3) Ruling
General Audit Procedures
How to Be a Good Auditor as a Team Leader
Contingency Theory in Auditing
How to Become Certified for ISO 9001
An audit can be an unpleasant surprise, or it can be a welcome opportunity to get your organization's affairs in order. While some audits – such as those performed by the IRS – come as a surprise, some companies hire independent outside auditors to conduct a planned audit. Regardless of the kind of audit in which a company is involved, the auditor will likely use the same four phases to perform the audit.
Planning the Scope of the Audit
In the planning phase, the auditor makes an effort to understand what kinds of documentation are needed, collects documents from previous audits and gathers preliminary statements from involved parties. During the planning phase, the auditor also begins to plan the scope of the audit and to determine what the objective of the audit is. In some non-sensitive cases, a letter is sent to the internal organization's auditing committee to let the group know that an audit is forthcoming.
Conducting a Preliminary Review
The auditor begins to evaluate the way that a company operates and takes into account the organization's internal processes. If any of these processes do not allow the auditor to perform the audit as well as he had planned, he may adapt to accommodate for the differences between his assumptions and the way the organization actually operates. For example, if an auditor comes in with the assumption that only a select few employees have access to the organization's bookkeeping software, when in actuality many employees have access, he may need to reevaluate how he plans to perform the audit.
The auditor holds an entrance conference with the organization being audited and will incorporate any recommendations made by the organization, if appropriate. Some of the processes that might be discussed include how an internal accountant approves purchases with petty cash, how an employee receives access to a company credit card and how mileage is reimbursed.
Completing the Fieldwork
The auditor will begin to interview employees in different areas of the organization to understand its general practices and processes. The auditor often performs this work on site. The auditor begins to be able to determine, during this phase, if the organization's operations and processes are working as effectively as they should.
The auditor also clearly identifies the areas that are not in compliance, or that are less effective than they need to be. For example, he may notice that an organization is not keeping records or filing documents as federal or local law mandates.
Producing a Written Audit Report
All of the work done during the first three phases culminates in the production and delivery of the audit report. In addition to identifying areas in need of improvement, the audit report also includes recommendations that list the processes the organization can follow to improve the way it operates.
For example, an auditor may recommend that an organization add an extra layer of approvals before a supervisor is able to okay purchases. An exit conference is held between the auditor and upper-level management to discuss the results of the audit.
Bowling State University: The Audit Process
AICPA: 10 Steps to a Successful Audit
West Virginia University: Audit Phases
Tax Audit Procedures
How to Conduct a Sales & Use Tax Audit
Six-Step Audit Process
How to Conduct an Effective HR Audit
Special-Purpose Government Audit Vs. a Corporation Audit
Checklist for an Accounting Audit
How to Manage Insubordination
Workplace Audit Checklist
How to Start a 501(c)(3) Organization
1 Tax Audit Procedures
2 How to Conduct a Sales & Use Tax Audit
3 Six-Step Audit Process
4 How to Conduct an Effective HR Audit


text:
Your View: Lehigh County has been in forefront of bail reform
By Jim Martin, Heather Gallagher and Maureen McManus
Lehigh County District Attorney Jim Martin says for more than 20 years Lehigh County and his office have been in the forefront of bail reform. (Morning Call File Photo)
Recently, Julie Thomases authored a Your View column critical of cash bail and local practice. Before publication, she had spoken with the director of Pretrial Services and attended a meeting of the Preliminary Hearing and Bail Committee, a subcommittee of our Criminal Justice Advisory Board. That meeting included a judge and representatives of the entire criminal justice system. She received factual information and statistics. However, the column sets forth inaccuracies about our bail practices.
For more than 20 years, Lehigh County and the district attorney have been in the forefront of bail reform that is only now being embraced in Philadelphia.
Lehigh Valley Pretrial Services — an organization the first of its kind in Pennsylvania and led by Director Maureen McManus for 38 years — with support from the district attorney, long ago implemented the alternatives to cash bail that Ms. Thomases suggests: supervised release, check-in with charged individuals, unsecured bonds. We welcome Philadelphia following our lead with these best practices.
Pursuant to Pennsylvania Supreme Court rules, bail is set at preliminary arraignment by a magisterial district judge (not by "county judges" as Thomases maintains). This occurs " ... without unnecessary delay" i.e. shortly after arrest. It is very rare that a representative from either the district attorney or the public defender is present.
In early 2018, the Philadelphia DA announced that he would no longer seek cash bail. But according to the October 2018 Pennsylvania Bail Watch Report, cash bail continues to be set there in the majority of cases. The presence of an assistant DA at preliminary arraignment is also very rare there.
Recently, the ACLU filed suit against Philadelphia Court Magistrates alleging violation of bail rules. According to Mary Catherine Roper, ACLU of Pennsylvania, "That is not anything the DA can fix, that is not something the public defender can fix, that is not something the city administration can fix ... these judges are not following orders and the only authority that can tell them to do that is the Pennsylvania Supreme Court."
We agree. However, there is something the district attorney and a robust pretrial services can do. It is what we have successfully been doing for years in Lehigh County.
Here, when bail is set, a Lehigh Valley Pretrial Services officer is available to the magisterial district judges during the business week to assist them in setting appropriate bail and to consider options other than cash bail. The officer interviews the accused, conducts a preliminary background check, and considers any rule-based relevant factors when making a bail recommendation. The district attorney's office almost always agrees to its recommendations which result in modification of bail and release.
LVPTS and the district attorney are founding members of TEAM MISA (mental health and substance abuse issues). This team includes stakeholders from most all service providers in the county, including the Office of the Public Defender, the Department of Corrections, Drug and Alcohol, and Mental Health Program. It is chaired by the first assistant DA.
Instead of cash bail, individuals identified at the first interview by LVPTS as MISA candidates are provided options for treatment and other services rather than pretrial incarceration.
For example inmate X is currently in Lehigh County Jail in lieu of bail with no other warrants or detainers. Rather than simply arrange release, LVPTS has instead recommended that he remain in jail for the time being because he is homeless and drug dependent. With the assistance of TEAM MISA, a place at an inpatient rehabilitation center has been secured. He will shortly be released to this facility.
In an ideal world, this alternative would have been available at the preliminary arraignment. But it takes a few days to determine needs and secure appropriate services. In the meantime, inmate X remains in a supervised setting where he receives the care he needs. There are many other similar examples but space limitation precludes detail.
On April 15, there were 306 pretrial detainees in Lehigh County Jail. Of those, 183 (60%) had new open charges with bail set but could not be released because detainers had been filed from other counties, or they faced parole or probation violations holding them in jail. Of the remainder, 73 were charged with felonies, including many with firearm offenses, and would not be eligible for released on your own recognizance bail.
There are public safety concerns and victims to consider when setting bail. And more than 96% of people charged are ultimately convicted, or have a tantamount disposition. Contrary to Thomases' assertion, it is extremely rare that people plead guilty only to secure earlier release.
We hope that this provides a more balanced view of bail and pretrial detention practices in Lehigh County.
James B. Martin, district attorney of Lehigh County; Heather F. Gallagher, chief of administration and chief of appeals for the district attorney; and Maureen McManus, executive director, Lehigh Valley Pretrial Services.
cash bail


text:
/*	$Header: /usr/sctpCVS/rserpool/lib/StateMachine.c,v 1.1 2006-05-30 18:02:01 randall Exp $ */

/*
 * Copyright (C) 2002 Cisco Systems Inc,
 * All rights reserved.
 *
 * Redistribution and use in source and binary forms, with or without
 * modification, are permitted provided that the following conditions
 * are met:
 * 1. Redistributions of source code must retain the above copyright
 *    notice, this list of conditions and the following disclaimer.
 * 2. Redistributions in binary form must reproduce the above copyright
 *    notice, this list of conditions and the following disclaimer in the
 *    documentation and/or other materials provided with the distribution.
 * 3. Neither the name of the project nor the names of its contributors
 *    may be used to endorse or promote products derived from this software
 *    without specific prior written permission.
 *
 * THIS SOFTWARE IS PROVIDED BY THE PROJECT AND CONTRIBUTORS ``AS IS'' AND
 * ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
 * IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
 * ARE DISCLAIMED.  IN NO EVENT SHALL THE PROJECT OR CONTRIBUTORS BE LIABLE
 * FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL
 * DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS
 * OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION)
 * HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT
 * LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY
 * OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF
 * SUCH DAMAGE.
 */
#include <StateMachine.h>

/******************************************/
/* distributor access functions of the SM */
/******************************************/
void
stateTimer(void *sm, void *timerNo)
{
  stateMachineS *obj;
  int *val;
  obj = (stateMachineS *)sm;
  val = (int *)timerNo;
  *val = 0;
  (*obj->currentState)(obj->objarg,STATE_MACH_TIMER,0,timerNo);
}

void
stateMessage(void *sm, messageEnvolope *msg)
{
  stateMachineS *obj;
  obj = (stateMachineS *)sm;
  (*obj->currentState)(obj->objarg,STATE_MACH_MESSAGE,0,(void *)msg);
}

void
stateStartStopFun(void *sm,int eventType)
{
  stateMachineS *obj;
  obj = (stateMachineS *)sm;
  if(eventType & DIST_CALL_ME_ON_START)
    (*obj->currentState)(obj->objarg,STATE_MACH_START,0,0);
  else if(eventType & DIST_CALL_ME_ON_STOP)
    (*obj->currentState)(obj->objarg,STATE_MACH_STOP,0,0);
}

void
stateAudit(void *sm)
{
  stateMachineS *obj;
  obj = (stateMachineS *)sm;
  (*obj->currentState)(obj->objarg,STATE_MACH_AUDITTICK,0,0);
}

int
stateFd(void *sm,int fd, int event)
{
  stateMachineS *obj;
  obj = (stateMachineS *)sm;
  (*obj->currentState)(obj->objarg,STATE_MACH_FD,fd,(void *)&event);
  return(0);
}

/* creation/destruction function */
stateMachineS *
createStateMachine(distributor *o,void *objarg,int numTimers,
		   stateFunction firstState,int noStartup)
{
  stateMachineS *ret;

  ret = calloc(1,sizeof(stateMachineS));
  if(ret == NULL){
    return(NULL);
  }
  ret->obj = o;
  ret->currentState = firstState;
  ret->lastFree = 0;
  ret->objarg = objarg;
  ret->noStart = noStartup;
  if(numTimers == 0){
    numTimers++;
  }
  ret->timerArray = calloc(numTimers,sizeof(int));
  if(ret->timerArray == NULL){
    free(ret);
    return(NULL);
  }
  ret->timerCnt = numTimers;
  memset(ret->timerArray,0,(sizeof(int) * numTimers));
  if(noStartup){
    dist_startupChange(ret->obj,stateStartStopFun,
		       (void *)ret,DIST_CALL_ME_ON_STARTSTOP);
  }else{
    /* if the no startup option is set, then call the
     * Start state right away.
     */
    (*ret->currentState)(ret->objarg,STATE_MACH_START,0,0);
  }
  return(ret);
}

void
destroyStateMachine(stateMachineS *obj)
{
  int i;

  if(obj->noStart == 0){
    dist_startupChange(obj->obj,stateStartStopFun,
		       (void *)obj,DIST_DONT_CALL_ME);
  }else{
    (*obj->currentState)(obj->objarg,STATE_MACH_STOP,0,0);
  }
  for(i=0;i<obj->timerCnt;i++){
    if(obj->timerArray[i] != 0){
      /* timer is running, stop it */
      dist_TimerStop(obj->obj, stateTimer, (void *)obj, (void *)&obj->timerArray[i]);
      obj->timerArray[i] = 0;
    }
  }
  free(obj->timerArray);
  memset(obj,0,sizeof(stateMachineS));
  free(obj);
}

/* Accesor to change state, could be used by the outside as well */
int
changeState(stateMachineS *obj,stateFunction newstate,int arg1,void *arg2)
{
  /* Exit state call may be removed .. not sure if we need this */
  (*obj->currentState)(obj->objarg,STATE_MACH_EXIT,arg1,arg2);
  obj->currentState = newstate;
  /* now call the new state and tell them that we have just entered */
  (*obj->currentState)(obj->objarg,STATE_MACH_ENTER,arg1,arg2);
  return(LIB_STATUS_GOOD);
}

/* Subscription things that the initial state should setup */

int
stateMachineAddFd(stateMachineS *obj,int fd, int events)
{
  return(dist_addFd(obj->obj,fd,stateFd,events,(void *)obj));
}

int
stateMachineDelFd(stateMachineS *obj,int fd)
{
  return(dist_deleteFd(obj->obj,fd));
}

int
stateMachineWantsMsg(stateMachineS *obj,int sctp_proto, int stream_no,int priority)
{
  int ret;
  ret = dist_msgSubscribe(obj->obj,stateMessage,sctp_proto,stream_no,priority,(void *)obj);
  return(ret);
}

int
stateMachineNoMsg(stateMachineS *obj,int sctp_proto, int stream_no,int priority)
{
  return(dist_msgUnsubscribe(obj->obj,stateMessage,sctp_proto,stream_no,(void *)obj));
}

int
stateMachineWantsAudit(stateMachineS *obj)
{
  return(dist_wants_audit_tick(obj->obj,stateAudit,(void *)obj));
}

int
stateMachineDisableAudit(stateMachineS *obj)
{
  return(dist_no_audit_tick(obj->obj,stateAudit,(void *)obj));
}

/* Timer control for state machine */
int *
startStateTimer(stateMachineS *obj,int sec, int usec)
{
  int i,fnd,ret;
  fnd = 0;

  for(i=obj->lastFree;i<obj->timerCnt;i++){
    if(obj->timerArray[i] == 0){
      fnd=1;
      break;
    }
  }
  if(!fnd){
    /* no timers left */
    for(i=0;i<obj->lastFree;i++){
      if(obj->timerArray[i] == 0){
	fnd=1;
	break;
      }
    }
  }
  if(!fnd){
    return(NULL);
  }
  obj->lastFree = i+1;
  ret = dist_TimerStart(obj->obj,stateTimer,sec,usec,(void *)obj,
			(void *)&obj->timerArray[i]);
  if(ret >= LIB_STATUS_GOOD){
    obj->timerArray[i] = 1;
    return(&obj->timerArray[i]);
  }
  return(NULL);
}

int
stopStateTimer(stateMachineS *obj,int *timerNo)
{
  int ret;
  ret = dist_TimerStop(obj->obj, stateTimer, (void *)obj, (void *)timerNo);
  if(ret >= LIB_STATUS_GOOD)
    *timerNo = 0;
  return(ret);
}

/******************************************/
/* Accesor function for outside to do a
 * call back
 */
/******************************************/

void
stateCallBack(stateMachineS *obj,int arg1,void *arg2)
{
  (*obj->currentState)(obj->objarg,STATE_MACH_CALLBACK,arg1,arg2);
}


text:
using System.Collections.Generic;
using System.IO;
using System.Linq;
using Drachenhorn.Xml.Data;

namespace Drachenhorn.Xml.Template
{
    /// <inheritdoc />
    /// <summary>
    ///     Manages all available Templates.
    /// </summary>
    public class TemplateManager : BindableBase
    {
        /// <summary>
        ///     Manager for all instances of SheetTemplates
        /// </summary>
        public static TemplateManager Manager { get; private set; } = new TemplateManager();

        #region c'tor

        private TemplateManager() { }

        #endregion c'tor

        #region Templates

        private IEnumerable<TemplateMetadata> _availableTemplates;

        /// <summary>
        ///     Gets the available templates.
        /// </summary>
        /// <value>
        ///     The available templates.
        /// </value>
        public IEnumerable<TemplateMetadata> AvailableTemplates
        {
            get
            {
                if (_availableTemplates != null)
                    return _availableTemplates;

                if (!Directory.Exists(Constants.TemplateBaseDirectory))
                    Directory.CreateDirectory(Constants.TemplateBaseDirectory);

                var result = new List<TemplateMetadata>();
                var files = Directory.GetFiles(Constants.TemplateBaseDirectory);

                foreach (var file in files)
                {
                    if (!file.EndsWith(Constants.TemplateExtension))
                        continue;

                    result.Add(new TemplateMetadata(file));
                }

                _availableTemplates = result;
                return result;
            }
        }

        /// <summary>
        ///     Gets the Template for the Path.
        /// </summary>
        /// <param name="path">Path to the template.</param>
        /// <returns>Selected TemplateMetadata-Object</returns>
        public TemplateMetadata GetTemplate(string path)
        {
            return AvailableTemplates.FirstOrDefault(x => x.Path == path);
        }

        /// <summary>
        ///     Resets the availableTemplates
        /// </summary>
        public void ResetAvailableTemplates()
        {
            _availableTemplates = null;
            OnPropertyChanged($"AvailableTemplates");
        }

        #endregion Templates
    }
}


text:
Q: What is the expression for the area enclosed by this shape? i.e., is there a closed form for this integral? Here is the graph of the shape I'm interested in. It's essentially an ellipse, but instead of the distances to the focal points summing to one, they multiply to one.
It has the equation $y^2 = -x^2 - c^2 + \sqrt{4x^2c^2 + 1}$, and I'd like to find the area under it. Just for the simple case where c < 0 (that is the shape does not expand into two regions), the X coordinate where the shape intersects the X axis is given by $\sqrt{1 + c^2}$ (solving the above equation for $y = 0$).
Since the shape is symmetrical over both the X and Y axes, it can be simplified to four times the area of one of the sections (in this case, quadrant 1). That results in the integral:
$\text{Area} = 4\int^\sqrt{1+c^2}_0 \sqrt{-x^2 - c^2+\sqrt{4x^2c^2 + 1}}dx$
Is there possibly a closed form for this? Or (like most weird integrals) does it have no closed form?

A: It seems that your curve is a Cassini oval.  If it is, the area , in general, cannot be found with elementary functions but only with elliptic integrals ( see also here).


The $2 trillion 2017 Tax Cuts and Jobs Act (TCJA) includes several provisions set to expire at the end of 2025. Now, GOP leaders have introduced a bill informally called "Tax Cuts 2.0" or "Tax Reform 2.0," which would make the temporary provisions permanent. And they falsely claim that making these provisions permanent will benefit the middle class.
ITEP analysis finds that extending the temporary tax provisions in 2026 would not be aimed at helping the middle-class any more than TCJA as enacted helps the middle-class in 2018.


Mumbai, Aug 10 (IBNS): The first look poster of upcoming Hindi film Sui Dhaaga has been released by the makers of the movie.
Film critic Taran Adarsh tweeted, "Trailer on 13 Aug 2018... First look poster of #SuiDhaaga - Made In India... Stars Varun Dhawan and Anushka Sharma... Directed by Sharat Katariya... Produced by Maneesh Sharma... 28 Sept 2018 release. #YashRaj"
The film stars Varun Dhawan and Anushka Sharma in the lead roles.
Sui Dhaaga is the first film where the two actors will be seen as an onscreen pair.
Sharat Katariya directorial film is slated to release on Sept 28.


text:
Have A Laugh: What Men Are REALLY Thinking!
If you have met your twin flame or if you've ever had a soul mate, or if you have ever known a man, this will make you laugh and cry (the good kind of tears.) A male friend of mine wrote this and I added a few to the list that I got from guys I know.
1. If you showed up for our date wearing a florescent orange jumpsuit and purple high top sneakers, we'd just think it was some kind of fashion statement. We really don't understand women's fashion as much as you'd like us to.
2. We hear your words when you talk to us. And, we really, really, really want to understand what you're saying. We really do.
3. We're a lot like your dog, which is why we like dogs so much. When you look at your dog, you know exactly how he feels. You can tell if he's happy or sad, hungry or scared, or if he's deep in doggie thought. We're just like him.
4. We really don't notice your "major zit" as much as you do. We may see it, but we really aren't that concerned about that 1/1000th of your body.
5. We do notice when you paint up your nails like the Sistine Chapel then encrust them with little jewels and dangly things. It both fascinates us as well as terrifies us.
6. We like it when you wear a pony tail. We also dig yoga pants.
7. Like squirrels, we are fascinated and entranced by sparkly things. We especially like sparkling earrings that don't look like they're going to cut us if we move in for a kiss.
8. When you only order a side salad as an entree, we aren't impressed and assume you're full of dieting willpower. We're wondering if something's wrong with the restaurant or if you have a crazy scary food allergy, and we assume we've done wrong.
9. We do notice your purse, but we don't notice your shoes (unless we have a foot fetish which is more common than you think, or unless you're in those purple high tops.) When you wear extremely expensive brands, we always wonder if you're going to expect us to furnish you with a lifestyle we can't afford.
10. Like I said, we notice your purse. if you have a ton of things in it, we sometimes assume you're "high maintenance."
11. We do secretly look at your hot friends. All. Of. Them.
12. We do actually slightly...kind of encourage the flirting with other women when you're not around even though we say we don't, because we like the attention. It lets us know we've still got it going on. But you have nothing to worry about, if we were interested in someone else, we'd have asked them out already and broken up with you.
13. On the flip side, if there's a woman who we know really, really likes us, we avoid her like the plague because we don't want to hurt her feelings or end up in some uncomfortable conversation/situation.
14. We do look at some kind of porn. For 50% of us, it's some kink we really don't want to share. it has nothing to do with you, and sometimes we even watch it because we're just bored.
15. We think women get into relationships to try and help mold us into better men; to change us, and we men get into relationships hoping the woman won't start to change.
16. We like to cuddle and have romantic pillow talk, even with women we're not in love with.
17. The farther away you are, the more romantic I can be, especially if I am married because it's "safe."
18. If I have a girlfriend and no children with her, don't wait on me. Ending it with a girlfriend is way easier than ending it with a wife. If I have a girlfriend and I've not ended it with her to be able to date you, I'm probably not going to.
19. If I'm a single guy and I've not asked you out, I'm either not interested or I'm into other guys.
20. We men want to feel as intensely as you do, we really do. But if it's just not happening, we will bail. We're really bad about using you women for sex, so be careful.
21. For us, "guy time" is a chance to be the horrible monsters we don't want you to know we like to be around each other, so please let us go with our guys.
22. We are very logical thinkers. We won't do something unless it makes sense to us. We also hate change, and we like things to remain on an easy, even keel.
23. We sometimes actually get physically sick at the thought of the woman we love being with another guy.
24. If you chase us, we will probably run out of instinct of being chased. if you stand still, we'l come forward.
25. We value our autonomy. Please don't steal it.
26. We usually do not deal with feelings unless we have to, so it's usually when something is going badly. That makes us feel out of control. An invitation to dissect and discuss our feelings is like an invitation to feel out of control, so we don't usually like to do that unless we have to.
27. It takes a lot of courage to ask you out, so if you're not interested please let us down easy.
28. We like it when you're relaxed and on an even keel. Cool. So be cool like Fonzie.
29. We want you to think we have everything totally under control and going well. Please never shame us, especially in public.
30. We sometimes will use physical intimacy to make up. And, we hope you won't start talking about whatever the fight was about when we're finished.


Math and M&Ms® go great together when introducing a modeling activity. Allow your learners to simulate population growth and decay of fish in a pond and share their reasoning for the change in fish. With such an impact we have on our environment, this activity should spark a discussion about the trends affecting the plants, mammals, and other creatures of this planet. Use the other activity listed in materials for a follow-up with population models including equations.
Students simulate peppered moth predators using SmartNotebook. In this life science lesson, students collect survival data and analyze results. They explain the importance of changes in species over time.


Tata Power Solar, India's largest solar energy company, and Tata Power's wholly-owned subsidiary has launched a complete residential rooftop solution in Nagpur. Mr. Atul Pande, President, Vidharbha Industrial Association, Mr. R. B. Goenka, Managing Director, R. K. Engineering, Mr. Gaurav Poddar, Director, S. S. Foods Products and Mr. Sarang Mahajan, General Manager, MEDA inaugurated the residential rooftop solutions today in Nagpur along with other senior dignitaries from the government and key decision makers from the corporate industry who also graced the launch event with their presence. The residential rooftop solutions are expected to save up to Rs. 50,000 annually for 25 years.
Safety is as an important aspect of this installation. The company ensures that work happens safely and effectively to prolong the life of the system. The residential rooftop segment will further strengthen the company's leadership position in solar rooftop segment, along with being key growth drivers in inspiring environment-friendly energy solutions. The Company recently launched this solution in Delhi, Mumbai, Bhubaneshwar, Ajmer, Gandhinagar, Bengaluru, Cochin, Chennai, Chandigarh, Hyderabad, Guwahati, Varanasi, Jamshedpur and Pune has received a great response from residential segment. Renewables are the new growth area, which will bring greater value and will align with the changing consumer needs.
Tata Power Solar, with 29 years of deep domain expertise, is one of the pioneering solar manufacturers in the world and India's largest specialized EPC player. Founded in 1989, the company was originally formed as a joint venture between Tata Power and British Petroleum Solar (BP Solar). As a pioneer and market leader in the solar space, headquartered in Bangalore, Tata Power Solar now operates independently as a wholly owned subsidiary of Tata Power.


text:
"Battleground" states are a product of winner-take-all laws, because it makes no sense for candidates to visit states where they are sure to win or sure to lose the popular vote within those states.
Alternately, spending precious campaign time and money where only a small number of votes can flip the entire electoral strength of a state in their favor, makes great sense financially and politically.
Since 2000, only 7 to 12 "battleground" states, ranging from small ones like New Hampshire to large ones like Florida, have controlled the outcome of presidential elections, undercutting the interests of as much as ¾ of the rest of the nation.
A National Popular Vote map would look more like this, making it stunningly clear that the country is just as much sagebrush, prairie, forest and farmland, than Republicans, Democrats or Independents.
In a NPV election, with state boarders deemphasized, individual votes all over the country would draw in candidates like magnets, giving all states the ear of the future president, (no matter which party wins) and many of the benefits that provides.
Over a million votes were cast in the small state of Utah in 2016. That's worth showing up for. Many presidential elections have been won or lost by less. When the whole nation is a battleground state, the voters in small states like Utah can no longer be ignored.
The traditional Electoral College map creates a totally misleading representation of party influence by literally painting each state as one political bulwark or another.
It's just not the case. In 2016, Utah went 54% Independent and Democrat, California went almost 40% Republican. Winner-take-all laws sequester those votes within state boundaries and then throws them away when the state goes "red" or "blue."
WINNER-TAKE-ALL ELECTORAL MAP 2016
BATTLEGROUND STATE MAP
POPULAR VOTE MAP (theoretical)
NYTIMES ELECTION 2016
Encourage people you know in states where the National Popular Vote Interstate Compact is being introduced to support the legislation. Send them the link to: OPEN STATES to find their legislators' and committee members' contact information anywhere in the nation.
Sign up for the NATIONAL POPULAR VOTE MARCH FOR 2020 on October 7th 2017. Join the movement to make the 2020 presidential election the first where every vote in every state is equal!
ALASKA:
NPV HB 175 has been put on pause for the 2018 session as the legislative sponsor wisely sees that to pass it out of committee now would give the bill a "cold" start in the 2018 session when it hits the house floor. Therefore, HB175 will be picked up in the 2018 session, having already passed the House State Affairs committee and had its initial hearing in the House Judiciary committee.
Click here to cut and paste sample letters
that can be modified (always in polite and respectful ways)
for emails, snail-mail or texts.
UTAH:
Save the date and stay tuned: NPV UTAH has signed up in solidarity with New Mexico and will be planning a National Popular Vote Day event on Saturday 10/7/17. Join this national movement, have a great time while creating awareness and support for the National Popular Vote Interstate Compact in preparation for Utah's 2018 legislative session. Utah NPV Day Festival: it's going to be FUN-damental!
National Popular Vote does not replace the Electoral College,
it replaces the winner-take-all laws that dominate it.
LATEST NEWS ON NPV - 7/12/17
The trouble with the Electoral College winner-take-all map:
Can either voting system be exploited?
Which voting system protects the interests of small states like Utah?
Does either system favor a party or region?
Does it really matter which system we use?
What makes conservatives raise eyebrows and liberals gasp?
What would no "sane" candidate ever do?
If you would like to be included in a weekly email update of NPV action across the nation or are interested in helping with this effort, please click on the "You Can Act" button or email NPV Utah:
The new president has unofficially endorsed a national popular vote very publicly, two times in the last five years. It's time for him to do it officially.
Help spread the word about the movement to reform the Electoral College.
Join the effort to make the new president accountable for what he said.
The Electoral College is part of the Constitution. The winner-take-all laws that dominate it are NOT, they are state laws that require all the electoral votes of a state be cast for the winner of the popular vote within that state. In a period extending from the 1790's through the 1800's, these winner-take-all laws replaced other state laws that before them, determined the way the president was elected.
Because the National Popular Vote does not change the Constitution, (just winner-take-all state laws that dominate the Electoral College) a constitutional amendment is not required.
The National Popular Vote Interstate Compact is itself, state legislation that since 2006 has been making it's way across the country and guarantees the presidency to the candidate with the most popular votes nationwide. The Compact currently has 10 member states and D.C. worth 165 electoral votes. When the minimum number of electoral votes required to win the presidency (270) are locked up with the addition of sufficient states equaling another 105 electoral votes, the Compact will trigger, and in the following election, all member states will appoint electors who are supporters of the national popular vote winner to cast their votes.
In that event, even if you DO NOT LIVE IN A MEMBER STATE, if you voted for president,
you are part of the National Popular Vote and YOUR VOTE WILL COUNT FOR PRESIDENT.
Winner-Take-All vs National Popular Vote:


In 2017, James H. McVey was a Miscellaneous Administration And Program at the Federal Acquisition Service in Washington, District Of Columbia. began working at the Federal Acquisition Service in 2016 with a starting salary of $160,300. Since then, 's salary has increased to $161,900 in 2017.
James H. McVey is a GS-15 under the general schedule payscale and is among the highest-paid ten percent of employees in the Federal Acquisition Service.
James H. McVey's 2017 pay is 82% higher than the average Miscellaneous Administration and Program across all agencies.
James H. McVey's 2017 pay is 98% higher than the average pay of a GS employee at the Federal Acquisition Service.


Atlas of Surgical Techniques for the Upper GI Tract and Small Bowel, by Drs. Ponsky and Rosen, presents state-of-the-art updates on the full range of surgeries for the upper GI tract and small bowel performed today. This title in the new Surgical Techniques Atlas series edited by Drs. Townsend and Evers offers you expert advice on a variety of techniques—open and interventional—to help you expand your surgical repertoire and hone your skills. Full-color illustrations and photographs enhance visual guidance and Expert Consult functionality gives you easy access to the full text online at expertconsult.com.
Includes convenient access to the full-text online as well as procedural videos that highlight pivotal moments and the techniques of the physicians who pioneered the procedures, showing you how to proceed.
Provides step-by-step guidance on a wide range of procedures, both open and interventional, giving you multiple options for approaching any challenge.
Examines the hottest topics in upper gastrointestinal and small bowel surgery.
Discusses pearls and pitfalls to help you avoid complications.
Presents more than 300 full-color illustrations and step-by-step intraoperative photographs for expert visual guidance.
Offers pre- and postoperative imaging studies that show the outcomes of various conditions following surgery.
Uses a consistent, easy-to-follow chapter format that includes clinical anatomy, pre-operative considerations, operative steps, post-operative care, and pearls and pitfalls to make reference easy.


Our house is situated in a calm area. The village centre, the station and the Nebelhorn cablecar can be reached by walking in about 10 minutes.
Parking space for our guests is available on private ground in front of the house.
W-LAN is available. We offer free bedding and towels during your stay.


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Shirur Assembly constituency is one of the Vidhan Sabha (legislative assembly) constituencies of Maharashtra state, western India. This constituency is located in Pune district, and it is a segment of Shirur (Lok Sabha constituency).

Geographical scope
The constituency comprises revenue circles Nhavare, Wadgaon Rasai
and Talegaon Dhamdhere, Shirur Saja and Karanjawane Saja of
Shirur revenue circle and Shirur Municipal council all belonging to Shirur taluka and revenue circles Wagholi and Urali Kanchan belonging to Haveli taluka.

Members of Vidhan Sabha

References

Assembly constituencies of Pune district
Assembly constituencies of Maharashtra

redpajama_set_name: RedPajamaWikipedia


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Dr Maria Cristina Profili (Italy), was reassigned from the post of WHO Representative to Turkey to the post of WHO Representative to Jordan effective from 1 September 2014.
Dr Profili holds a Degree in Medicine and Surgery with a Specialization in Infectious Diseases and two Masters degree in Health Services Management and Health Economics. She's also authors of several scientific publications.
Prior joining the World Health Organization, she worked for the Italian Ministry of Foreign Affairs and Italian Public Health Institute based in Egypt (1993–1996), Bosnia and Herzegovina (1997–1999), coordinating and managing public health programmes and emergency response operations.
In 1999 she joined the World Health Organization, based in Kosovo/UN1244 resolution (1999), Serbia and Montenegro (2000–2001) and The Former Yugoslav Republic of Macedonia (2002), coordinating and managing public health programmes and emergency response operations.
From 2002 to beginning of 2009, she moved to the WHO Regional Office for Europe based in Copenhagen, working as Desk Officer for the emergency preparedness and response programme, coordinating emergency operations in the European Region, including Balkans and North Caucasus.
In 2005, she was seconded to other WHO Regions to support Tsunami-affected countries: Thailand, Sri Lanka and Indonesia (Regional Office for South East Asia), Pakistan earthquake operation (Regional Office for the Eastern Mediterranean).
In 2006, she was acting Head of WHO country office based in Kiev.
In 2008, she was deployed to Georgia to support the emergency operation.
In 2007–2008, she had a special assignment from the WHO Regional Director for Europe to coordinate the Ministerial Conference on Health Systems, Health and Wealth which culminated in the Tallinn Charter endorsed by 53 Member States of the WHO European Region.


Nutrition – Sober Coaching – Inspiring you to live a sober lifestyle.
The food we put in our body is directly related to our mood and how we feel. The energy we have daily is a direct result of the food we eat. Unhealthy foods can make us feel lethargic or cause us to develop other unhealthy habits or triggers.
Through our partnership with Nutrition Pros, we offer personalized nutritional planning where you will have a nutrition expert that will guide your meal options and help you choose a well-balanced diet. Nutrition Pros serves to educate, motivate, and drive change through better food choices. We are dedicated to educating and assisting our clients with a systematic process through personal, one-on-one coaching. Whether the goal is weight loss, weight gain, or a sustainable healthy lifestyle, transformational success begins with Nutrition Pros.
With the proper nutritional planning, your energy will be more abundant and you will begin to develop healthy eating habits to support your recovery.


Apna Time Aayega is the new song from the movie Gully Boy sung by Ranveer Singh and music is produced by DIVINE, Ankur Tewari. This song Apna Time Aayega Lyrics is written by DIVINE & Ankur Tewari. This song is considered as one of the best songs from the movie.


What if I told you that there's a way to adopt the best diet of your life that will transform your body inside out without the obstacles listed above.
You see, a lot of the obstacles I mentioned are not actually as much of a problem as you think they are. In fact, one of them is a complete myth and waste of time. And that would be the one that has you constantly counting how many calories are coming in and whether or not you're eating too many.
So let me bust this myth right now!
and if your diet is low on carbs, your body will actually be a less effective fat burning machine.
There are 3 ways to making eating unbelievably healthy unbelievably easy.
Do you know that everything you love to eat and drink, you actually learned to.
Let me ask you, what was your first experience of coffee? Or how was your first taste of beer? Did say to yourself, "Yummy, that's tasty". If you remember back to your very first sip you probably wanted to spit it out because it was bitter. But over time and with social influence, you grew to like the taste of beer, coffee, whiskey or any other food or beverage.
You can use the same acquired taste to learn to appreciate healthy and nutritious foods. It takes some time to develop your buds like it did since your first time drinking beer but if you can get the same level of appreciation for good, clean healthy foods, you're going to actually crave them.
This sounds counter intuitive but the reason people fall off the wagon when dieting or trying to eat better is because they make anything they eat the devil.
By telling yourself, "I'm going to stop eating fries" or "That's it! No more sugar for me." you're actually creating resistance in yourself and resistance takes up will power.
In fact, studies have shown that will power is measurable and the less will power you have, the harder it is to get yourself to eat the right foods and stop eating the wrong foods. So why set yourself up to lose from the start?
It's much more effective to save your energy and attention on eating healthy food than it is on not eating junk food.
You like you fries and ice cream? I say, go for it. But while you get to still enjoy that, also look for ways to integrate good, healthy nutritious meals in your day and maybe even look for healthier versions of the foods you love.
Eat what you love but also learn to love better food.
How do you experience food? is it all about the taste?
The way to fully experience and enjoy food is to pay attention on all your senses during and after you ingest it.
Firstly, to enjoy eating healthy, don't limit your focus to how it tastes. Use texture, smell and sight to influence your experience.
If you want to really enjoy a salad (the dish that many find boring) don't just throw some vegetables in a bowl. Add something that gives it texture like seeds and nuts, pick your favorite dressing, use as many colors as possible and add a good protein source.
Secondly, how does that food feel after? How do you feel hours after? Do you feel fresh and clear or are you bloated and foggy? Are you energized or are you feeling sluggish? How does what you eat feel like in your stomach?
Use your body's feedback of the experience of what you eat to tell you if its good for you.
The experience of food extends way past your taste buds and its invaluable to pay attention to how you're experiencing it later down the track.
Eating healthy so that you can have the best chance possible to cultivate the body you dream of is totally doable and a lot easier than you think.
Don't just go on diets that last a week or a month only to get temporary results. Integrate a way of eating so that you never have to go on a diet again.


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The Little Monsters 1-900 Number
Zombie Bongo Limbo
Local Ghoul Makes Good
By Strange Jason in Music, Punk
Blase Debris
I lived around the Albany, New York region for some-three years. I like Albany. If there was more there for me, I wouldn't mind living there. But the job prospects sucked and it had the strange cultural live of a town that might be pretty cool, maybe if more bands came by, maybe not. If you're planning to go to RPI in Troy or Union in Schenectady or even U of Albany, you won't be stuck in some backwater. There will be something for you to do.
Albany hosts one of the best used music shops I've been in, ever. Last Vestige is a good example of how the independent music store can adapt in order to survive in a world of Amazon.com and iTunes. Knowing it's audience, college students, Last Vestige deals mainly in used vinyl but also in CDs, tapes and the occasional piece of music memorbilia. I was able to find both '3 Hits from Hell' by the Crimson Ghosts and the Minutemen's 'Paranoid Times' there. I also found Blase Debris and Duane "Pinebox" Beers.
Blase Debris is Duane's band. Duane worked at Last Vestige. He, like most of the staff at Last Vestige, was friend and talked to anyone about anything. He's a friendly guy who looks like a survivor of the original Misfits, which isn't that far since he used to be in a Misfits cover band. Blase Debris isn't a Misfits knock off. It's a horror punk, but it's got its own sound. It was hard for me to hear the scratchy voice of the clerk behind the counter where I would pick up choice used CDs switch it up and get this more looping, deep in the throat singing voice.
If you're in the Albany area, stop by Last Vestige. You'll be able to pick up a Blase Debris release direct from the source. It would be like buying Misfits gear from Lordi, NJ or catching a Black Flag show in LA. Except you won't be in New Jersey and have less chance of having your head kicked in.
Blase Debris, horror punk
Strange Jason
Out of the two co-founders of Gravediggers Local 16, Strange Jason is certainly the one who is named Jason.


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Previous / Number 1 returns to Supercars grid as part of Holden tribute Next / Supercars Adelaide: Feeney wins as van Gisbergen penalised
Supercars / Adelaide Race report
Supercars Adelaide: Mostert leads emotional Walkinshaw one-two
Chaz Mostert made a perfect start to Holden's final weekend in Supercars, leading a Walkinshaw one-two in Adelaide.
Andrew van Leeuwen
Dec 3, 2022, 9:10 AM
In the early stages of the race it looked to be a battle between front-row starters Cam Waters and Scott Pye.
Waters led Pye across the first stint, the gap steadily increasing to around 2.5s before Pye took his first stop on lap 24.
Waters followed suit two laps later, the Tickford driver resuming with a comfortable margin over Pye – only to nearly throw it away on lap 28 when he clipped the wall at Turn 11.
That put Pye right under his rear wing, Waters defending into the last corner as Pye ran wide trying to get past.
Shane van Gisbergen was another driver that looked in the hunt early on with a stirring drive from the back of the grid.
He worked his way into the Top 10 within 12 laps and was well-placed, with plenty of fuel, in 11th after his first stop.
However a lap 38 safety car, sparked by Jack Le Brocq burying his Holden in the tyre wall at Turn 11, changed the complexion of the race.
The majority of the field hit the lane for a second stop, the likes of Waters and Pye falling just short of clearing the 140-litre minimum fuel drop.
That meant they would need a third stop, while Mostert, Nick Percat (who stopped twice behind the safety car) and James Courtney were among those to squeeze enough fuel in to satisfy the regulations.
There was still a question mark over their fuel, though, with plenty of saving required to get home.
When the race went green on lap 41 van Gisbergen's hopes unravelled thanks to an unsuccessful pass attempt on Mostert as they battled over what was effectively fourth place.
The Kiwi tried to go around the outside at Turn 6, the pair making side-by-side contact that led to van Gisbergen nosing into the wall.
The delay dropped van Gisbergen all the way back to 19th on the road.
Waters, meanwhile, scrambled to clear the non-stoppers, getting through Chris Pither on Lap 45 and then Lee Holdsworth three laps later.
Once in front he bolted in an effort to put a margin on Mostert knowing he needed that third stop.
The charge was short-lived, both Waters and Pye diving back into the lane on Lap 50 when the safety car was called due to another van Gisbergen blunder.
Start action
Photo by: Edge Photographics
This time he ended up in the wall at Turn 11, van Gisbergen able to back himself out, but would later retire due to the damage.
With Waters, Pye and Anton De Pasquale all stopping Mostert found himself in the lead for the Lap 52 restart – but needing to save fuel to get to the finish.
Waters, meanwhile, dropped back to eighth in queue, and lost more spots on the restart when he out-braked himself into Turn 4.
As he desperately tried to recover he clashed with Todd Hazelwood at Turn 5, Hazelwood collecting the wall before being hit in the passenger side door by Will Brown.
That prompted a third safety car which gave leader Mostert some breathing room in terms of fuel.
It also ruined Waters' race thanks to a drive-through penalty for his role in the crash.
The race went green again on lap 58, Mostert surviving a brief challenge from Andre Heimgartner, who had filtered up to second, before settling into the lead.
Even better for Mostert was that Percat managed to get past Heimgartner and into second.
A well-fuelled Pye was still a contender at the restart, only for his hopes to go up in smoke when he was hit by Bryce Fullwood and taken out of the race at Turn 9.
With the early contenders out of the running, and the safety of his teammate as rear gunner, Mostert was able to cruise through the final stint of the race and score a fairytale win for Holden's most famous team on the brand's final weekend in Supercars.
It was also Mostert's first win on the iconic Adelaide circuit.
"A good old classic fuel race, who knew that was in store," said Mostert.
"I struggled with the car most the race, it was pretty edgy out there. I had to get my elbows out with a few people. It was a tough race.
"It's so good to get a one-two. It's just hard work and dedication."
While Heimgartner dropped out of contention with cramps, Percat found himself under pressure from Courtney across the final stint.
But the hometown hero was able to hold the Tickford Mustang off to secure the WAU one-two.
Brodie Kostecki finished fourth ahead of Tim Slade and Mark Winterbottom.
Will Davison ended up as the best of the Shell Fords in seventh followed by Broc Feeney, Heimgartner and Holdsworth.
The Adelaide 500 continues tomorrow with qualifying for Race 2 at 10:50am.
Number 1 returns to Supercars grid as part of Holden tribute
Supercars Adelaide: Feeney wins as van Gisbergen penalised
Auer to miss Bathurst, Craft-Bamboo seeking replacement
Lawson to drive Red Bull F1 car at Bathurst
Ranking the top 10 Supercars drivers of 2021
Autosport writers' most memorable moments of 2022
By Autosport Staff
The season just gone was a memorable one for many of our staff writers, who are fortunate enough to cover motorsport around the world. Here are our picks of the best (and in some cases, most eventful) from 2022
When Nissan ruled Australia with its 'Godzilla' Group A special
The Nissan Skyline R32 GT-R was the fastest Group A touring car ever. It cleaned up at the Bathurst 1000 and in the Australian Touring Car Championship, and is fondly remembered by the drivers who monstered it to success on the world-famous Mount Panorama
By Andrew van Leeuwen
It may have been a one-man title fight in Supercars this season, but behind dominant champion Shane van Gisbergen were some fascinating performances. Autosport picks out the best drivers of the 2021 campaign.
The well-travelled racer now Supercars' elder statesman
James Courtney has been around the block in his motorsport career it's fair to say. After a single-seater career cut short, he's won everything there is to win in Supercars. Following a rocky ride recently in the Australian category, he's found a happy hunting ground with Tickford Racing, as Andrew van Leeuwen explains
How taming his temper shaped Supercars' slow-burn star
His decision to leave Brad Jones Racing was the biggest shock of the Australian Supercars silly season so far. But for Nick Percat, it comes as the culmination of a personal journey that has made him into one of the most rounded drivers in the series, now in search of a seat that can make him a champion
Why replacing Supercars' GOAT with a teenager is worth the risk for T8
On the face of it, picking an 18-year-old rookie to replace arguably the greatest Supercars driver of all time is a risky move. But as Jamie Whincup takes up a team principal role and hands his car to Broc Feeney, it's one that he is confident will be rewarded in the fullness of time - time which wasn't afforded to Whincup in his early days
Can DJR still be a Supercars powerhouse after Penske?
OPINION: Roger Penske's operation helped lift Dick Johnson's faltering Ford team back to the top of Australian tin-tops. But, despite The Captain's departure, along with star driver Scott McLaughlin, there's no reason to expect an imminent decline from DJR
Why Whincup's next move is no calculated gamble
Supercars' most successful team of the past 15 years is set for a radical shakeup next year when Jamie Whincup retires from driving and takes over the reins at Triple Eight. But the team's outgoing boss Roland Dane has full faith that he'll be up to the task


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Top Glove says continuously upheld good labour practices
>Media & Events > News>Top Glove says continuously upheld good labour practices
Top Glove Corporation Bhd says it has continuously upheld good labour practices and complied with requirements of labour laws and best practices, while ensuring adequate measures are in place to protect the safety and well-being of its workforce.
It was accorded an "A" rating in a social audit conducted from May 23 to 26 this year by Amfori, a leading global business association for open and sustainable trade, the group said in a statement in demonstration of its commitment to ethical labour practices and further dispelling allegations of forced labour taking place in its manufacturing facilities.
"The recent Amfori audit, and earlier third-party audits which garnered good ratings, provide independent verification that there is no element of forced labour in our manufacturing facilities", said general manager of human resources, William Yap.
The group said as a socially responsible employer and industry leader, Top Glove has consistently striven to comply with and exceed international standards and expectations with regard to labour-related matters.
This includes a Zero Cost Recruitment Policy under which its bears all recruitment-related fees for its foreign workers who arrived from the year 2019 onwards and absolutely no passport confiscation where workers have full custody of their passports.
The group said other ongoing good practices and improvements since 2019 in social compliance include continuous compliance with Malaysian labour authorities on payment of wages, absolutely no forced or excessive overtime, decent accommodation and facilities, employee safety and health as its foremost priority as well as upholding the highest standards of corporate governance.
Top Glove said since January 2019, the group has attended to more than 100 external social audits of its factories, conducted by established international audit firms.
"In addition, the group has proactively engaged with various organisations with a view to improving its social compliance and performance.
"We will continue to engage with our stakeholders and are also committed to keep improving worker welfare, which remains a priority for Top Glove," Yap added.


Addiction affects the way a person takes care of him or herself. The addiction takes over every aspect of life and takes priority over all responsibilities. When a person is living with an addiction, they often forget about self-care. An addicted brain needs to be clear of toxic substances and retrained to function normally. Yoga and meditation are effective tools to use for clearing the mind before and throughout recovery.
Yoga in addiction treatment helps to alleviate stress and despair, especially during recovery. Yoga employs breathing techniques and other ways to bring deep relaxation while clearing the mind of toxic substances. Tommy Rosen wrote about the benefits of yoga in recovery for the Huffington Post and said, "The physical practice of yoga, along with breath practices, serves to detoxify the body and to calm the mind. Yoga improves circulation and lung capacity, it stretches and strengthens muscles, it helps to work out the organs and improves digestion and it regulates the nervous and endocrine systems. You will simply be more comfortable in your mind and body if you practice yoga. For this reason, I consider yoga to be a central and necessary component of recovery from addiction." Yoga will not end addiction or relieve stress of family codependency, but is very helpful to the recovery process.
Yoga helps to establish connections with family and acquaintances, but more importantly, with yourself. Addiction causes a loss of connections, but yoga allows you to get to know yourself and find meaning and purpose in a life of sobriety. Maintaining mindfulness contributes to the healing of the mind, body, and soul after addiction. A clear, healthy mind promotes good mental and physical health. Yoga has a healing energy and is not forced, but a way of allowing healing.
Breathing techniques and mediation are important components of yoga healing. It incorporates deep sleep relaxation and internal recharging. Breathing is proven to make people healthier by changing the human nervous system. Meditation is a strong tool for recovery.
Yoga works for family members who are affected by their loved one's addiction. Chronic stress can be deadly. Yoga helps to alleviate stress and restore connections with self and family. Reaping the benefits of yoga requires commitment. There is no cure for addiction. However, there is hope for recovery.


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New $9M Urbana Health Center to Open this Spring
Chip Hubbs, president and CEO of Memorial Health, speaks during a ground breaking ceremony for a new Memorial Health outpatient medical center in Urbana Friday. Bill Lackey/Springfield News-Sun Staff
By Matt Sanctis - Springfield News-Sun Staff Writer
Construction is on track for a new $9 million outpatient center in Urbana by a Marysville medical group and a grand opening is likely by late April or early May.
Memorial Health's outpatient medical center will be located at 1958 E. U.S. 36 and will house urgent care, lab testing services, rotating physician specialists, expanded primary care and more. The roughly 30,000-square-foot facility is expected to create 12 new permanent jobs and retain 17 jobs in Urbana.
Melanie Ziegler, a spokeswoman for the company, said the project is on schedule and no delays are anticipated.
The medical group will also host a groundbreaking open house event and ceremony at Memorial Hospital in Marysville as part of a separate project. The company is undergoing a $50 million expansion and renovation of Memorial Hospital.
That project involves construction of two buildings, both an inpatient pavilion and an outpatient pavilion on the main campus at 500 London Ave. in Marysville.
Read about the recent economic development success stories in Champaign County!
Urbana Health Center


The generous support of individual philanthropists help us take big steps towards our goal that by 2050 everyone who develops breast cancer will live – and live well.
Breast Cancer Now strives to be at the forefront of research into breast cancer. In a few short years, we have enabled vital drugs including Palbociclib and Ribociclib to be available for routine NHS use to help those who are living with breast cancer, whilst also funding research projects that will help those who are diagnosed and living with breast cancer now and in the future.
These projects range from The Generations Study - a study taking place over 40 years which is looking into the lifestyles of over 100,000 women to see what may cause increased risk of breast cancer - to work looking at the spread of breast cancer to other areas of the body and projects focussed on ensuring a good quality of life to those living with secondary breast cancer.
Breast Cancer Now is working tirelessly towards our 2050 goal – and with your support, you can be a part of this journey.
As a major giver to Breast Cancer Now, your partnership with us will mean you get to see our work first hand and further your understanding into how our research and work is saving lives.
If you would like to be a major giver to Breast Cancer Now, please get in touch with our Philanthropy team by emailing majorgifts@breastcancernow.org or calling us on 020 7025 2475.
Future Dreams have supported Breast Cancer Now for 10 years, join them in their celebration.


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The Mystery of "Whoonga"
NeuroskepticBy NeuroskepticMarch 2, 2011 1:05 AM
According to a disturbing BBC news story, South African drug addicts are stealing medication from HIV+ people and using it to get high:
'Whoonga' threat to South African HIV patients
"Whoonga" is, allegedly, the street name for efavirenz (aka Stocrin), one of the most popular antiretroviral drugs. The pills are apparantly crushed, mixed with marijuana, and smoked for its hallucinogenic effects.
This is not, in fact, a new story; Scientific American covered it 18 months ago and the BBC themselves did in 2008 (although they didn't name efavirenz.)
16.00 pm: In fact the picture is even messier than I first thought. Some sources, e.g. Wikipedia and the articles it links to, mostly from South Africa, suggest that "whoonga" is actually a 'brand' of heroin and that the antiretrovirals may not be the main ingredient, if they're an ingredient at all. If this is true, then the BBC article is misleading.
Editand see the Comments for more on this...
Why would an antiviral drug get you high? This is where things get rather mysterious. Efavirenz is known to enter the brain, unlike most other HIV drugs, and psychiatric side-effects including anxiety, depression, altered dreams, and even hallucinations are common in efavirenz use, especially with high doses (1,2,3), but they're usually mild and temporary. But what's the mechanism?
No-one knows, basically. Blank et al found that efavirenz causes a positive result on urine screening for benzodiazepines (like Valium). This makes sense given the chemical structure:
Efavirenz is not a benzodiazepine, because it doesn't have the defining diazepine ring (the one with two Ns). However, as you can see, it has a lot in common with certain benzos such as oxazepam and lorazepam.
However, while this might well explain why it confuses urine tests, it doesn't by itself go far to explaining the reported psychoactive effects. Oxazepam and lorazepam don't cause hallucinations or psychosis, and they reduce anxiety, rather than causing it.
They also found that efavirenz caused a false positive for THC, the active ingredient in marijuana; this was probably caused by the gluconuride metabolite. Could this metabolite have marijuana-like effects? No-one knows at present.
Beyond that there's been little research on the effects of efavirenz in the brain. This 2010 paper reviewed the literature and found almost nothing. There were some suggestions that it might affect inflammatory cytokines or creatine kinase, but these are not obvious candidates for the reported effects.
Could the liver be responsible, rather than the brain? Interestingly, the 2010 paper says that efavirenz inhibits three liver enzymes: CYPs 2C9, 2C19, and 3A4. All three are involved in the breakdown of THC, so, in theory, efavirenz might boost the effects of marijauna by this mechanism - but that wouldn't explain the psychiatric side effects seen in people who are taking the drug for HIV and don't smoke weed.
Drugs that cause hallucinations generally either agonize 5HT2A receptors or block NMDA receptors. Off the top of my head, I can't see any similarities between efavirenz and drugs that target those systems like LCD (5HT2A) or ketamine or PCP (NMDA), but I'm no chemist and anyway, structural similarity is not always a good guide to what drugs do.
If I were interested in working out what's going on with efavirenz, I'd start by looking at GABA, the neurotransmitter that's the target of benzos. Maybe the almost-a-benzodiazepine-but-not-quite structure means that it causes some unusual effects on GABA receptors? No-one knows at present. Then I'd move on to 5HT2A and NMDA receptors.
Finally, it's always possible that the users are just getting stoned on cannabis and mistakenly thinking that the efavirenz is making it better through the placebo effect. Stranger things have happened. If so, it would make the whole situation even more tragic than it already is.
Cavalcante GI, Capistrano VL, Cavalcante FS, Vasconcelos SM, Macêdo DS, Sousa FC, Woods DJ, & Fonteles MM (2010). Implications of efavirenz for neuropsychiatry: a review. The International journal of neuroscience, 120 (12), 739-45 PMID: 20964556


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Home » Golden State Foods promotes Buechel to president of KanPak US
Golden State Foods promotes Buechel to president of KanPak US
Chad Buechel, new president of KanPak US
Photo: Golden State Foods
IRVINE, CALIF. — Chad Buechel has been promoted to president of KanPak US, a Wichita, Kan.-based subsidiary of Golden State Foods, one of the largest diversified suppliers to the foodservice and retail industries.
Mr. Buechel will be responsible for all aspects of KanPak's US business, including its production of more than 18 million gallons of dairy products each year. In addition, he will establish and execute KanPak's US strategic growth plan, including revenue growth, profitability, customer satisfaction, operating efficiency, quality, and safety.
Mr. Buechel has more than 25 years of experience in the food manufacturing industry, most recently as vice president of liquids at Golden State Foods. He earlier was an area plant director for Synagro and has worked as a plant manager at the Kraft Heinz Co., Nestle USA and Pepsi Bottling Group.
"We are excited to have someone with Chad's leadership and experience join the KanPak family," said Larry McGill, chief executive officer of KanPak US. Mr. McGill also is a corporate officer at Golden State Foods. "His knowledge of GSF and running large award-winning plants will continue to help us grow and provide opportunities for our team members. His people skills are evident, as well as his passion for the business."
Mr. Buechler received a bachelor's degree in business administration at National University in San Diego.
Golden State Foods acquires full ownership of KanPak
Golden State Foods acquires KanPak China
Golden State Foods acquires KanPak U.S.
Two leaders appointed at Golden State Foods
Tim Hortons promotes Schwan to regional president of U.S. and Canada