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International Journal of Pharmacology and Toxicology
Are synthetic peptides real toxic allergens? a comprehensive literature review and update on therapeutic and adverse toxic immunogenic potentials of peptides -truth or dare
Sahar Y. Issa DR. SAHAR YOUNES IBRAHIM ISSALECTURER FORENSIC MEDICINE & CLINICAL TOXICOLOGY-FACULTY OF MEDICINE-ALEXANDRIA UNIVERSITYConsultant Toxicologist & head of Toxicology Department DPCCemail: syissa@moh.gov.saMobile Phone: +2011142490525 http://orcid.org/0000-0001-5432-5028
R. Carmichael Helix Biomedix
https://doi.org/10.14419/ijpt.v8i1.30275
Mutagenicity, Peptides, Skincare Products, Amino Acids, Skin.
In the pharmaceutical industry, there is much debate about how to translate current guidelines on biotherapeutic immunogenicity testing into a real-life strategy that meets the regulatory requirements of newly discovered pharmaceutical peptides. This paper will present a consensus view on the essential elements for biotherapeutic immunogenicity consideration for pharmaceutical synthetic peptides to ensure patient safety and allow successful market entry. This paper's scope is limited to aspects relevant to the biotherapeutic synthetic peptide pharmaceuticals and does not include necessary academic immunogenicity studies. Medical research shows little support for antigenic or allergic reactions to short synthetic peptides. These negligible results warranted a detailed literature review to examine antigens and allergens linked to peptides.
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text:
import collections
import extractor_util as util
import data_util as dutil
import random
import re
import os
import sys
import string
import config
import dep_util as deps

CACHE = dict()  # Cache results of disk I/O

# This defines the Row object that we read in to the extractor
parser = util.RowParser([
          ('doc_id', 'text'),
          ('section_id', 'text'),
          ('sent_id', 'int'),
          ('words', 'text[]'),
          ('dep_paths', 'text[]'),
          ('dep_parents', 'int[]'),
          ('lemmas', 'text[]'),
          ('poses', 'text[]'),
          ('ners', 'text[]')])

# This defines the output Mention object
Mention = collections.namedtuple('Mention', [
            'dd_id',
            'doc_id',
            'section_id',
            'sent_id',
            'wordidxs',
            'mention_id',
            'mapping_type',
            'mention_supertype',
            'mention_subtype',
            'gene_name',
            'words',
            'is_correct'])

### CANDIDATE EXTRACTION ###
HF = config.GENE['HF']
SR = config.GENE['SR']

def read_pubmed_to_genes():
  """NCBI provides a list of articles (PMIDs) that discuss a particular gene (Entrez IDs).
  These provide a nice positive distant supervision set, as mentions of a gene name in
  an article about that gene are likely to be true mentions.

  This returns a dictionary that maps from Pubmed ID to a set of ENSEMBL genes mentioned
  in that article.
  """
  pubmed_to_genes = collections.defaultdict(set)
  with open('%s/onto/data/pmid_to_ensembl.tsv' % util.APP_HOME) as f:
    for line in f:
      pubmed,gene = line.rstrip('\n').split('\t')
      pubmed_to_genes[pubmed].add(gene)
  return pubmed_to_genes

def select_mapping_type(mapping_types):
  mapping_order = HF['ensembl-mapping-types']
  for m in mapping_order:
    if m in mapping_types:
      return m
  assert False, ','.join(mapping_types)

def extract_candidate_mentions(row):
  gene_name_to_genes = CACHE['gene_name_to_genes']
  mentions = []
  for i, word in enumerate(row.words):
    if HF['require-one-letter']:
      if not re.match(r'.*[a-zA-Z].*', word):
        continue
    if (word in gene_name_to_genes):
      matches = gene_name_to_genes[word]
      mapping_types = set()
      for (eid, canonical_name, mapping_type) in matches:
        mapping_types.add(mapping_type)
      mapping_type = select_mapping_type(mapping_types)
      if len(word) >= HF['min-word-len'][mapping_type]:
        m = create_supervised_mention(row, i, gene_name=word, mapping_type=mapping_type)
        if m:
          mentions.append(m)
  return mentions

def contains_sublist(lst, sublst):
  if len(lst) < len(sublst):
    return False, None
  n = len(sublst)
  for i in xrange(len(lst) - n + 1):
    if sublst == lst[i:i+n]:
      return True, (i,i+n)
  return False, None

def detect_manual(gene_name, words):
  manual_pairs = SR['manual-bad']
  for names in manual_pairs:
    definitions = manual_pairs[names]
    if gene_name in names:
      for definition in definitions:
        def_lst = [d.lower() for d in definition.split(' ')]
        contains, def_boundaries = contains_sublist([w.lower() for w in words], def_lst)
        if contains:
          def_start, def_stop = def_boundaries
          definition = words[def_start:def_stop]
          return ' '.join(definition)
  return None

### DISTANT SUPERVISION ###
VALS = config.GENE['vals']
def create_supervised_mention(row, i, gene_name=None, mapping_type=None, mention_supertype=None, mention_subtype=None):
  """Given a Row object consisting of a sentence, create & supervise a Mention output object"""
  word = row.words[i]
  mid = '%s_%s_%s_%s' % (row.doc_id, row.section_id, row.sent_id, i)
  m = Mention(None, row.doc_id, row.section_id, row.sent_id, [i], mid, mapping_type, mention_supertype, mention_subtype, gene_name, [word], None)
  dep_dag = deps.DepPathDAG(row.dep_parents, row.dep_paths, row.words)

  phrase = ' '.join(row.words)
  lemma_phrase = ' '.join(row.lemmas)
  if SR.get('post-neighbor-match') and i < len(row.words) - 1:
    opts = SR['post-neighbor-match']
    post_neighbor = row.words[i+1]
    for name,val in VALS:
      if len(opts[name]) + len(opts['%s-rgx' % name]) > 0:
        match = util.rgx_mult_search(post_neighbor, opts[name], opts['%s-rgx' % name], opts[name], opts['%s-rgx' % name], flags=re.I)
        if match:
          return m._replace(is_correct=val, mention_supertype='POST_MATCH_%s_%s' % (name, val), mention_subtype=match)

  if SR.get('bad-genes'):
    if i > 0:
      prev_word = row.words[i-1]
    else:
      prev_word = ''
    if i < len(row.words) - 1:
      next_word = row.words[i+1]
    else:
      next_word = ''
    if next_word != 'gene' and prev_word != 'gene':
      for bad_gene in SR['bad-genes']:
        if re.search(bad_gene, gene_name):
          return m._replace(is_correct=False, mention_supertype='BAD_GENE')

  if SR.get('manual-bad'):
    detected = detect_manual(gene_name, row.words)
    if detected is not None:
      return m._replace(is_correct=False, mention_supertype='MANUAL_BAD', mention_subtype=detected)

  if SR.get('pre-neighbor-match') and i > 0:
    opts = SR['pre-neighbor-match']
    pre_neighbor = row.words[i-1]
    for name,val in VALS:
      if len(opts[name]) + len(opts['%s-rgx' % name]) > 0:
        match = util.rgx_mult_search(pre_neighbor, opts[name], opts['%s-rgx' % name],
                                     opts[name], opts['%s-rgx' % name], flags=re.I)
        if match:
          return m._replace(is_correct=val, mention_supertype='PRE_NEIGHBOR_MATCH_%s_%s' % (name, val), mention_subtype=match)

  if SR.get('phrases-in-sent'):
    opts = SR['phrases-in-sent']
    for name,val in VALS:
      if len(opts[name]) + len(opts['%s-rgx' % name]) > 0:
        match = util.rgx_mult_search(phrase + ' ' + lemma_phrase, opts[name], opts['%s-rgx' % name],
                                     opts[name], opts['%s-rgx' % name], flags=re.I)
        if match:
          # backslashes cause postgres errors in postgres 9
          return m._replace(is_correct=val, mention_supertype='PHRASE_%s' % name, mention_subtype=match.replace('\\', '/'))

  ## DS RULE: matches from papers that NCBI annotates as being about the mentioned gene are likely true.
  if SR['pubmed-paper-genes-true']:
    pubmed_to_genes = CACHE['pubmed_to_genes']
    pmid = dutil.get_pubmed_id_for_doc(row.doc_id)
    if pmid and gene_name:
      for (mention_ensembl_id, canonical_name, mapping_type) in CACHE['gene_name_to_genes'][gene_name]:
        if mention_ensembl_id in pubmed_to_genes.get(pmid, {}):
          return m._replace(is_correct=True, mention_supertype='%s_NCBI_ANNOTATION_TRUE' % mention_supertype, mention_subtype=mention_ensembl_id)
          break

  ## DS RULE: Genes on the gene list with complicated names are probably good for exact matches.
  if SR['complicated-gene-names-true']:
    if m.mapping_type in HF['ensembl-mapping-types']:
      if re.match(r'[a-zA-Z]{3}[a-zA-Z]*\d+\w*', word):
        return m._replace(is_correct=True, mention_supertype='COMPLICATED_GENE_NAME')

  if SR['all-canonical-true']:
    if m.mapping_type == 'CANONICAL_SYMBOL':
      return m._replace(is_correct=True, mention_supertype='%s_ALL_TRUE' % m.mention_supertype)

  if SR['all-symbols-true']:
    if m.mapping_type in HF['ensembl-mapping-types']:
      return m._replace(is_correct=True, mention_supertype='%s_ALL_TRUE' % m.mention_supertype)

  if SR.get('neighbor-match'):
    opts = SR['neighbor-match']
    for name,val in VALS:
      if len(opts[name]) + len(opts['%s-rgx' % name]) > 0:
        for neighbor_idx in dep_dag.neighbors(i):
          neighbor = row.words[neighbor_idx]
          match = util.rgx_mult_search(neighbor, opts[name],  opts['%s-rgx' % name], opts[name],  opts['%s-rgx' % name], flags=re.I)
          if match:
            return m._replace(is_correct=val, mention_supertype='NEIGHBOR_MATCH_%s_%s' % (name, val), mention_subtype='Neighbor: ' + neighbor + ', match: ' + match)

  return m

def get_negative_mentions(row, mentions, d, per_row_max=2):
  """Generate random / pseudo-random negative examples, trying to keep set approx. balanced"""
  negs = []
  if d < 0:
    return negs
  existing_mention_idxs = [m.wordidxs[0] for m in mentions]
  for i, word in enumerate(row.words):
    if len(negs) > d or len(negs) > per_row_max:
      return negs

    # skip if an existing mention
    if i in existing_mention_idxs:
      continue

    # Make a template mention object- will have mention_id opt with gene_name appended
    mid = '%s_%s_%d_%s' % (row.doc_id, row.section_id, row.sent_id, i)
    m = Mention(dd_id=None, doc_id=row.doc_id, section_id=row.section_id, sent_id=row.sent_id, wordidxs=[i], mention_id=mid, mapping_type=None, mention_supertype="RANDOM_NEGATIVE",mention_subtype=None, gene_name=None, words=[word], is_correct=None)

    # Non-match all uppercase negative supervision
    if word==word.upper() and len(word)>2 and word.isalnum() and not unicode(word).isnumeric():
      if random.random() < 0.01*d:
        negs.append(m._replace(mention_supertype='ALL_UPPER_NOT_GENE_SYMBOL', is_correct=False))

    # Random negative supervision
    elif random.random() < 0.005*d:
      negs.append(m._replace(mention_supertype='RAND_WORD_NOT_GENE_SYMBOL', is_correct=False))
  return negs

if __name__ == '__main__':
  # load static data
  CACHE['gene_name_to_genes'] = dutil.gene_symbol_to_ensembl_id_map()
  CACHE['pubmed_to_genes'] = read_pubmed_to_genes()
  # unnecessary currently b/c our doc id is the pmid, thankfully
  # CACHE['doi_to_pmid'] = dutil.read_doi_to_pmid()

  # generate the mentions, while trying to keep the supervision approx. balanced
  # print out right away so we don't bloat memory...
  pos_count = 0
  neg_count = 0
  for line in sys.stdin:
    row = parser.parse_tsv_row(line)

    # Skip row if sentence doesn't contain a verb, contains URL, etc.
    if util.skip_row(row):
      continue

    # Find candidate mentions & supervise
    mentions = extract_candidate_mentions(row)

    pos_count += len([m for m in mentions if m.is_correct])
    neg_count += len([m for m in mentions if m.is_correct is False])

    # add negative supervision
    if pos_count > neg_count and SR['rand-negs']:
      negs = get_negative_mentions(row, mentions, pos_count - neg_count)
      neg_count += len(negs)
      mentions += negs

    # print output
    for mention in mentions:
      util.print_tsv_output(mention)

redpajama_set_name: RedPajamaGithub


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The Build, Part IV: Mechanic's Time Warp
Our Toyota FJ project is turning into a serious time sink.
byBenjamin Preston| UPDATED May 9, 2021 6:43 PM
Benjamin PrestonView benjamin preston's Articles
benjamachine
It's been awhile since you've heard from The Build. There's a good reason for that. Remember when I griped about all the problems with our project Land Cruiser? After delving deeper into the dark, cavernous recesses of vehicular neglect and mechanical ineptitude, the list of things in need of fixing and/or replacement has grown. We're basically spelunking at this point. Send help.
So, quick update: The engine, transmission and transfer case have been plucked. Ditto the fuel tank, spare tire, interior and most of the accessories under the hood.
That doesn't sound so bad. What are you whining about?
On these older, well-used vehicles, the path to restoration is littered with roadblocks. One afternoon, I couldn't figure out how to get the wiring harness out of a deep crevice in the intake manifold (that's on top of the engine, so it looked easy enough). Another, when I'd planned to remove the engine and transmission together by pulling the 4WD transfer case, I discovered that, in order to do so, the entire transfer case had to be disassembled, in situ. (More on that later.)
Didn't you expect to run into problems?
Yes. But you never really know what you're going up against until you're up against it. Beforehand, and after the fact, pulling an engine doesn't seem like such a big deal. But there are so many things attached to it that must be disconnected before it'll come out. When those things are rusty and/or covered with dirty oil, it complicates the process.
Cait Knoll/TheDrive.com
Explain.
Well, after realizing I'd have to pull the engine by itself, then yank the transmission and transfer case from the bottom, it also became clear that the transmission and transfer case needed to be supported in two places to facilitate safe removal. Together, they're unwieldy and difficult to balance; the weight distribution is odd. I ended up resting the transmission on a low-lift transmission jack and the transfer case on a floor jack, then elevating the truck clear of the whole mess with the lift. In the Stygian blackness of the truck's oily, flaky underside, I missed a wire or two. For a moment, the bulk of the transmission began to tilt sideways...
Oh, oh! What happened next?
I lowered the truck and disconnected the wires.
That was really anticlimactic.
Sorry. I did have a little hazardous flirtation with the gas tank, though.
Go on...
You're supposed to be able to remove it by draining the gas, yanking off a few bolts and lowering away. But, here, most of the bolts were rusted into a section of the frame. I ended up cutting out a big piece with a sawzall. The shop owner, Carlos, stood behind me, watching sparks fly from the saw's blade into the void between the gas tank and frame.
Not for Carlos.
But no fires, right?
Nope. It just took way longer than anticipated to get the tank out. The important part is that the underside of the car was exposed to allow rust descaling. We'll talk about that later.
Bummer. I like fire. Hold on, though. What about the transfer case thing from earlier?
O.K., so we're removing the original Toyota and transmission to make way for a more potent Chevrolet V8 and auto tranny, both of which are easier to build up and find parts for. The transfer case is setup to work with the original Toyota axles, and can be attached to the Chevy guts with a special adapter. Or, at least, so I've heard.
From who? Seriously, who keeps telling you this stuff? That guy who sold you the truck? The one who made tapestries and called himself "The Grateful Dad"?
Funny you should mention that. When I dug into the transfer case to get it off the transmission, I found that some redneck (I won't mention any names, but the Grateful Dad said the transmission was replaced during his tenure as owner) had welded together some big, expensive parts inside of the transfer case that should definitely not have been welded together.
Sounds like a time sink.
As a wise man at the Denver airport rental shuttle stop once told me: "It always takes longer than it does."
You're weird. So what else is taking so long?
Well, getting our junkyard Chevy van engine to the machine shop went smoothly enough. But sitting in traffic to and from Queens added plenty of time to the build.
Ugh. Queens, man.
Yep. Every time. Besides traffic, there's reading. I've found that taking things apart—or putting them together—without research can lead to costly breakages and delays. The typical obstacle, however, is usually just some little unexpected head-scratcher of a problem. Also, cleanup. After several hours of work, oil, rust flakes and solvents are splattered everywhere. Tools are filthy and in disarray. It's always a good idea to tidy up to avoid losing tools, parts and fasteners, and to keep the garage from turning into one of those grimy nightmares.
Sweet. Thanks, mom.
Just sayin'. Point being: That's the nature of the beast, and why big projects like this take so long to complete. If the home mechanic can justify ditching family and friends for several hours at a time to wrench on a project vehicle, though, the payoff is just that much sweeter. We still have a ways to go on ours, but already a faint light is beginning to appear way down at the end of the tunnel.
That's probably just fumes from those solvents you mentioned before.
Maybe. But, I have to say, seeing the glimmer feels pretty good.
I'm sure it does. But the truck still needs a lot before it can do neat stuff. You know, like move under it's own power. What's next?
The machine shop, rebuilding our Chevy V8, and trying to get the damn thing installed.
Then you'll do neat stuff?
The neatest. Stay tuned..
BuildsCulture

redpajama_set_name: RedPajamaCommonCrawl


text:
Posts tagged 'college'
« Older Entries |
Dawood College of Engineering Students Problems
Raza Adil Khan emailed from Commissioner Society, Abu-ul-Hasan Isphahani Road, Gulshan-e-Iqbal: The road behind Dawood College of Engineering and Technology (DCET) is littered with garbage. People living in nearby houses dump garbage almost every day on the said spot. They don't realize that the students studying in DCET have to go through an ordeal as stink is coming out from it and sometimes it becomes unbearable to sit in the classroom. The town administration should take some concrete steps to address the issue on permanent basis.
Meanwhile, cleanliness condition in Commissioner Society is in shambles. Garbage and accumulated sewerage water in streets creates difficulties for pedestrians. The awful smell emanating from the overflowing manholes is also of great concern for the area residents. The sweepers of the city government only clean the main roads and never bother to sweep the streets of the locality.The news.
Posted in Education news | Leave a Comment »
Tags: college, Dawood, Engineering, problems, students
Government College University`s Young Journalists` Society
JOURNALISM is not only a profession but also a passion and young journalists can excel in this career through extensive readings and hectic reporting at the grass roots level.
Senior journalists and anchorpersons said this at a discussion on `Challenges confronting the fourth pillar of the state` organised by the Government College University`s Young Journalists` Society.
Journalist Rashid Rehman said the media had become a powerful player but "lifafa journalism" or paid reporting had also grown enormously. He said that it had become more and more challenging for editors to sift out genuine news from motivated and hoax stories.
Anchorperson and columnist Aftab Iqbal said maintaining the quality of news reports and upholding of journalistic values were the biggest challenge being faced by the media these days. "Truth should be presented – as much as it is needed," he added.
GCU-YJS President Amina Ahmed said it was a matter of disgrace and embracement that Pakistan had been declared the most dangerous country for journalists.
GCU Vice-Chancellor Prof Dr Ikramul Haq and guest journalists presented certificates and shields to YJS executive committee members for the sessions 2010-2011 and 2009-2010. The YJS executive committee for the session 2010-2011 consisted of Amina Ahmed (president), Shakila Rehman (senior vice-president), Sheikh Mateen (senior vice-president), Arooma Shahzad (vice-president), and Rizwan Khan (general secretary). Other office-bearers include Azib Warraich, Javeria Liaqat, Sana Irshad, Kashif Fayyaz, Usama Safdar, Salman Mehmood, Saima Nawaz, Aqsa Khalid, Ushna Butt, Ajab Khan and Umair Asif.
Later, GCU Nazir Ahmed Music Society members Imran Fida, Saba Shafqat, Saad Farooq, Mohsin Abbas and Hassan performed and enthralled the audience at the musical night.Dawn.
Tags: college, Government, Journalists, society, Universitys, Young
Govt fails to adjust promoted college teachers
LAHORE:The Punjab government s failure to adjust 165 female college teachers after their promotion/ selection as assistant professor, despite a lapse of a couple of months, has been irking the teachers and their family members.
Earlier, the Punjab Higher Education Department had posted hundreds of teachers, both male and female, after their promotion/ selection as assistant professor (BS-18) from Lecturer (BS-17), but many female teachers refused to join and got extension on the pretext that the new place of their posting was not suitable for them. Subsequently, a summary was moved by the department to the Chief Minister s Secretariat, seeking his approval to adjust/post these teachers after conversion and down-gradation of posts, etc.
Sources privy to the developments said that the summary was approved by Chief Minister Shahbaz Sharif last month but the issue has not yet been resolved. They said the Higher Education Department, in many of the cases, had recommended shifting of posts to adjust the female teachers but the same was tuned down by the Finance Department on the pretext the CM had not approved the same.
The sources said if the government failed to address the issue during the ongoing summer vacation, a large number of colleges of the province would be without teaching faculty, hampering academic activities and causing academic loss to students.
Talking to The News, a number of teachers awaiting postings said the delay was multiplying their troubles as, despite approval of the CM, the teachers were uncertain about their future. They demanded the chief minister take notice of the delay and provide relief to them so that they might resume their duties without any problem. The teachers seeking anonymity said many of the female teachers, after promotion to/ selection in the next grade, were transferred from their previous colleges to far away areas, which did not suit them according to the prevailing socio-economic circumstance.
It is pertinent to mention that the CM had formed a three-member committee comprising Punjab Higher Education secretary Haseeb Athar, provincial Minister for Education Mujtaba Shuja ur Rehman and Punjab Law Minister Rana Sana Ullah Khan which had recommended adjustment of female teachers as one-time consideration keeping in view their problems.
A Higher Education Department official, seeking anonymity, said the department had prepared its reply over objection of the Finance Department, and expected that the issue would be resolved soon. However, he added, the teachers were also responsible for their problems. Being government servants, they should go wherever they are sent, he maintained.
When contacted, Higher Education secretary Haseeb Athar said posting of teachers was a regular issue and the department had so far posted around 1,100 teachers after promotion in the ongoing stint. He said the problem surfaces each time a faculty member shows reluctance to be posted as per directions of the department. He, however, claimed that the issue related to posting of the female teachers would be solved within a week.The news.
Tags: adjust, college, fails, promoted, teachers
Raza Adil Khan emailed from Commissioner Society, Abu-ul-Hasan Isphahani Road, Gulshan-e-Iqbal: The road behind Dawood College of Engineering and Technology (DCET) is littered with garbage.
B.A. Both Parts part I and Part- II result 2010-2011 karachi university
B.A. Part- II & Both Parts (Regular) Annual Examination 2010
(EXAMINATIONS DEPARTMENT)
Candidates bearing the following seat numbers are hereby declared to have Passed
B.A. Part- II & Both Parts (Regular) Annual Examination 2010.
-BA (Part-II/Both) Regular Annual Exam 2010
Tags: 1st position, 2nd position, 3rd position, Annual Examination 2010, Annual Examination 2010 karachi university, B.A. Part- 1 result 2010, B.A. Part- 1 result 2010 karachi university, B.A. Part- 1 result 2011, B.A. Part- 2 result 2010, B.A. Part- 2 result 2010 karachi university, B.A. Part- 2 result 2011, B.A. Part- I & Both Parts, B.A. Part- I & karachi university, B.A. Part- I Privete result 2010, B.A. Part- I Privete result 2011, B.A. Part- I Regular result 2010, B.A. Part- I Regular result 2011, B.A. Part- I result 2010, B.A. Part- I result 2010 karachi university, B.A. Part- II & Both Parts, B.A. Part- II & karachi university, B.A. Part- II Privete result 2010, B.A. Part- II Privete result 2011, B.A. Part- II Regular result 2010, B.A. Part- II Regular result 2011, B.A. Part- II result 2010, B.A. Part- II result 2010 karachi university, B.A. Part- II result 2011, B.A. Part- Iresult 2011, B.A. Part- one Annual Examination result 2010, B.A. Part- one Privete result 2010, B.A. Part- one Privete result 2011, B.A. Part- one Regular result 2010, B.A. Part- one Regular result 2011, B.A. Part- one result 2010, B.A. Part- one result 2011, B.A. Part- one result karachi university, B.A. Part- two Annual Examination result 2010, B.A. Part- two Privete result 2010, B.A. Part- two Privete result 2011, B.A. Part- two Regular result 2010, B.A. Part- two Regular result 2011, B.A. Part- two result 2010, B.A. Part- two result 2011, college, examiners, first position, First Stands Second, First Stands Third, girls top position, Karachi colleges, Karachi University, karachi university B.A. Part one result 2011, karachi university B.A. Part- 1 result 2010, karachi university B.A. Part- 1 result 2011, karachi university B.A. Part- 2 result 2010, karachi university B.A. Part- 2 result 2011, karachi university B.A. Part- I result 2011, karachi university B.A. Part- II result 2011, karachi university B.A. Part- one Annual Examination result 2010, karachi university B.A. Part- one result 2010, karachi university B.A. Part- two Annual Examination result 2010, karachi university B.A. Part- two result 2010, karachi university B.A. Part- two result 2011, privete, Privete B.A. Part- I result 2010, Privete B.A. Part- I result 2011, Privete B.A. Part- II result 2010, Privete B.A. Part- II result 2011, Privete B.A. Part- one result 2010, Privete B.A. Part- one result 2011, Privete B.A. Part- two result 2010, Privete B.A. Part- two result 2011, Regular, Regular B.A. Part- I result 2010, Regular B.A. Part- I result 2011, Regular B.A. Part- II result 2010, Regular B.A. Part- II result 2011, Regular B.A. Part- one result 2010, Regular B.A. Part- one result 2011, Regular B.A. Part- two result 2010, Regular B.A. Part- two result 2011, second position, third position, University of Karachi, UNIVERSITY OF KARACHI B.A. Part- one result, Unqualified
Student Loan Scheme HEC program 2011
BRIEF ABOUT STUDENT LOAN SCHEME:
Pursuant to the announcement made by the Federal Finance Minister in his 2001-2002-budget speech, a STUDENTS LOAN SCHEME (SLS) for Education was launched by the Government of Pakistan in collaboration with major commercial banks of Pakistan (NBP, HBL, UBL, MCB and ABL). Under the Scheme, financial assistance is provided by way of Interest Free Loans to the meritorious students who have financial constraints for pursuing their studies in Scientific, Technical and Professional education within Pakistan.
Tags: ABL, ADMINISTRATOR OF THE SCHEME, Agriculture, Biology, Business Management Sciences, Chemistry, college, Commerce, commercial banks of Pakistan, committee comprising, Computer Science, DAWA and Islamic Jurisprudence, Deputy Governor, Economics, Electronics, Engineering, For Graduation, For Ph.D, For Post-Graduation, Government of Pakistan, HBL, HEC program 2011, high powered, Information, LL.B/LL.M Sharia, loan for Islamabad students, loan for karachi students, loan for lahore students, loan for pakistani students, loan for students, Mathematics, MCB, Medicine, Molecular Biology & Genetics, National Bank of Pakistan, NBP, Oil Gas & Petro-Chemical Technology, Other Natural Sciences, pakistan Student Loan bank, pakistan Student Loan Scheme, Physics, SCHEME, SLS, State Bank of Pakistan, Statistics and Econometrics, Student Loan Scheme, STUDENTS LOAN, System and Technology including hardware, UBL, University
Swabi college hostel a picture of neglect
Swabi, June Students staying in the only hostel of the Swabi Postgraduate College have been facing many problems due to negligence of the college administration.
The students told this correspondent on Tuesday that the hostel was the most neglected buildings of the college and needed immediate attention of the principal.
Usually the students leave the hostel during summer vacations but there are still some who have to stay to prepare for the examination. Majority of the students belong to the far-flung mountainous region of Gadoon Amazai and they have not option but to stay in the hostel despite almost no facilities.
The students alleged that the sanitation staff did not perform their duty and the dining hall was presenting a view of an archeological site as all the walls had been blackened by the smoke coming from the kitchen. The students said they had no option but to stay in the hostel.
The students have to rely on hand fans most of the time due to prolonged loadshedding, which has also badly affected their preparation for the upcoming BA/BSc examination. They said they were forced to pass sleepless nights due to hide and seek of the electricity.
The students said only one washroom was functioning in the hostel while the remaining had been chocked. "There is always a big line to the washroom early in the morning," said one of the students. "An awful smell was emanating from there", he complained.
A student, Gul Nawar Shah who hails from mountainous region of Utala said: "You are talking about the warden. We have even appealed to the ministers and other officials to direct the sanitation staff to clean the washrooms but to no avail".
Mohammad Pervez Khan, the hostel warden, was not available for comment.
However another official said that a grant for bringing about improvement in the hostel had been approved. Dawn
Tags: college, Postgraduate, problems, Swabi, Swabi Postgraduate College


Below I have put together a list of things that you can pray for each day.
I believe it's very important to pray together with your children, that way they can also learn how to pray for themselves. Teach them that these are things they should ask for in their own prayers as well.
Do you have any more suggestions? Please feel free to comment below and let us know what else do you pray about for your children.


Bongalong™ produces authentic, local, handmade designer Smokin' vases, quality smoking accessories and apparel for connoisseurs and truth seekers. Globally, legalisation of cannabis is imminent! South Africa is next!
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We are the brand that will change social perceptions of Cannabis by putting it out there, forcing people to look at the issues to freely and publicly discuss the benefits of legalisation. We bring style and design to the cannabis market. Raising funds product by product, for the legal fight. Spreading the word through rallies, media events, social gatherings and community projects.
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*In case an extra person occupies the apartment Ang. 136 ,-/ US $ 77,- extra per month is charged.
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2nd month upon check-in together with the first month rent.


Wow, what an amazing week we've had with the Indiegogo campaign! When we checked this evening, we have received $2,125 in donations from 31 different people! Not only that, we're told that the campaign has been viewed 397 times so far. Amazing! Thank you to everyone who is donating, and everyone who is helping us spread the word. We're getting closer and closer to our goal of $6,915 - there are still 5 days remaining in the campaign, please continue to help us spread the word!
We also just heard from another school - Our Lady of Providence - that they have completed a fundraiser and are getting ready to send in their donation. This will add to the $2,800 collected so far from the May 11th fundraiser!
We have been in touch with St. Albert Le Grand, and will be sending the school the first 750,000 CFA (about $1,575 CDN) to get this year's project under way. The focus this year will be to continue (and hopefully complete) the rehabilitation of the school buildings on the main school site (some photos of the buildings that are going to be rehabilitated are provided below).
We look forward to providing you updates this summer as the project progresses! We'll also be providing an update for you in July to report out on how the Indiegogo campaign finished.
We hope that you are all having an enjoyable summer!


New to the practice this year, Wajiha quickly become a key member of the Higher Education team working on concept and interior designs for several inner-London University projects. Wajiha enjoys designing contemporary and aesthetically pleasing spaces which improve the quality of life and finding innovative solutions to any project challenge. She has strong technical design and visual presentation skills and a good-humoured, enthusiastic approach.


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Does "Big Food" play a role in the obesity epidemic?
I'd argue yes, but still believe that individuals are responsible for their weight (genetic metabolic disorders excluded). Here's a little more on the debate occurring in the public health realm. Enjoy and Happy Friday!
The food and beverage industry has a huge and growing influence on the obesity crisis, but "Big Food" is not met with the same skepticism as other industries that influence public health, according to the editors of PLoS Medicine.
"Food, unlike tobacco and drugs, is necessary to live and is central to health and disease," the editors wrote online in an editorial kicking off a new series on the interplay between the food and beverage industry and public health. "And yet the big multinational food companies control what people everywhere eat, resulting in a stark and sick irony: one billion people on the planet are hungry while two billion are obese or overweight."
The editors said that while other big business interests -- such as the alcohol, tobacco, and pharmaceutical industries -- are often easy targets on which to blame public health ills, the food and beverage industry, for the most part, has gotten a pass.
Food and beverage companies are shaping global health conversations, in part by branding themselves as "nutrition companies" and presenting at major conference and at high-level UN meetings, the editors wrote. Food companies often partner with global health groups for health and nutrition initiatives, which is a conflict of interest, according to PLoS, because of food companies' primary goal: selling food.
"Why does the global health community find this acceptable?" the editors wrote.
"To promote health, industry would need to make and market healthier foods so as to shift consumption away from highly processed, unhealthy foods," nutrition and public health professor Marion Nestle, PhD, from New York University, and sociologist David Stuckler, PhD, MPH, from Cambridge University wrote in an accompanying essay. "Yet, such healthier foods are inherently less profitable."
The public health arena and governments too often turn a blind eye to the role of processed foods in obesity, and the "uncomfortable reason" is that because taking action would require taking on the "powerful Big Food companies with strong ties to and influence over national governments," the authors wrote.
Nestle and Stuckler said that the 10 largest food companies control half of all food sales worldwide. Three-fourths of the the world's food sales involved processed foods, which is a "driving force behind the global rise in consumption of sugar-sweetened beverages and processed foods enriched in salt, sugar, and fat," they wrote.
Nestle and Stuckler also argued that the food industry isn't doing enough to curb obesity.
"They should support initiatives such as restrictions on marketing to children, better nutrition standards for school meals, and taxes on sugar-sweetened beverages," they wrote. "The central aim of public health must be to bring into alignment Big Food's profit motives with public health goals. Without taking direct and concerted action to expose and regulate the vested interests of Big Food, epidemics of poverty, hunger, and obesity are likely to become more acute."
The Grocery Manufacturers Association -- the trade group for food and beverage companies -- responded to the series by highlighting all the ways it says it works to improve health, including introducing tens of thousands of new healthier food items, shifting advertising so that 100% of ads seen in kids' shows promote "better-for-you" products, and putting nutrition labeling on the front of packaged foods to make it harder to miss.
Another article published in PLoS compared the soda and tobacco industries, arguing that the "social responsibility" campaigns of both types of companies are really profit-oriented campaigns masquerading as social responsibility.
The comparison between the industries was flatly rejected by the American Beverage Association. "There is simply no comparison between soda and tobacco -- not among our products, nor our business practices," the group said. "Tobacco in and of itself is harmful -- in any amount; our beverages are not."
The nonalcoholic beverage industry has worked to reduce obesity in the form of offering smaller portioned drinks and drinks with fewer calories, clear labeling, and supporting exercise and balanced lifestyle programs, the American Beverage Association said in a statement.


Totally Bamboo's Chicken Cutting Board is light, super strong, totally green and all too fun. It is 5/8 of an inch thick, which means that it's maneuverable and easy to store. It's also durable; it offers tri-ply, cross laminate construction with a specially formulated high temperature adhesive. What more, this beautiful board is made of strong, eco friendly bamboo. The benefits of using bamboo are numerous. For example: bamboo is 16 percent harder than maple, yet easy on your knives, it's naturally anti-microbial and it's eco friendly; it holds the promise of a sustainable, cost effective, and ecologically responsible alternative to the widespread clear cutting of our old growth forests. Totally Bamboo uses organically grown Moso bamboo, so you need not worry about harmful pesticides or fertilizers. Plus, this bamboo is not a food source, or a habitat, for the Giant Panda. Totally good for you and totally good for the environment. What more? Board is easy to maintain. Wash with warm water and occasionally use Totally Bamboo's Revitalizing Oil to extend life and keep it looking beautiful. Board measures 13-inch by 10-inch by 5/8-inch.


Helicopter Links is a worldwide directory of helicopter information. Please see our Site Map for all categories.
Helicopter Links lists helicopter manufactures (and gyrocopter manufacturers), helicopter operators, suppliers, services, trade shows, events, magazines, associations, museums and more.
Please see our Site Map for a complete list of our helicopter categories.
We find our information online. We hand-check all sites and hand-place all our links. Our site does not connect to any online database. What is showing on a company's website is what we place on our site.
If you know a company's information is incorrect, we'd appreciate a phone call or email. If you would like to see your own company or favorite helicopter related company to be listed on Helicopter Links, please call or email us.
Helicopter Links main focus is on piloted helicopter links. There is some cross over linking to tiltrotor, VTOL, gyroplanes and other flying machines; however, we do do not link to unmanned air vehicles (UAVs) at this time. This could change at some point in the future.
Banner ads always rise to the top of the listings by seniority of advertiser.
Trade Shows are listed by date of event.
We do appreciate emails from people providing us new links or correcting outdated ones. We welcome anyone's link suggestions because if we are having trouble finding it online, we need someone to point it out to us. It does not matter if you work for a helicopter company or if you are a simply a helicopter enthusiast. Your phone call or email does make a difference on Helicopter Links.
For your information, I have provided some word usage and graphics for your use when linking to Helicopter Links. Please see our media page for our logos and usage. Or you may contact us by phone or email to discuss this further.
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For those asking: Helicopter Links does not sell or broker helicopters or helicopter parts or helicopter accessories. Helicopter Links does not fund helicopter research projects, new product builds, partner in new product helicopter development and does not partner in STC development.


where they live. On the other hand, several tropical species of flowering plant, such as the African baobab tree and the Australian ironwood, rely on fruitbats to pollinate them. Fruitbats also disperse plant seeds to new places and habitats.
The other major group of bats, the Microchiroptera or microbats, is quite ecologically diverse. Many of these microbats feed on insects, using their echolocation ability to find flying or crawling insects and their superb flying skills to catch them. Insect-eating bats are supremely good at what they do: a single little brown bat can catch and eat 600 mosquitos in an hour. Thus, bats play an important role in regulating insect populations; in those places where bat populations have been severely reduced by human activity, the numbers of fruit flies and other pests have risen dramatically.
Other microbats have adopted a diet of fruit, flowers, pollen, or nectar. Like their fruitbat cousins, these bats may occasionally damage crops or gardens, but on the whole play a beneficial role in transporting seeds and in pollinating several species of plants. Plants that are bat-pollinated include avocados, guava, mangoes, bananas, agave (from which tequila is made), and the giant saguaro cactus of the southwestern North American desert.
Still other bat species feed on fish, frogs, lizards, small rodents, small birds, and even other bats. And while bats have an evil reputation for sucking blood, only three out of the thousand or so species of bat actually feed on blood. These vampire bats are found only in tropical Central America, and usually feed on livestock, although humans may also be unwitting "blood donors." They make a small, painless incision in the skin of a sleeping mammal and lap up the blood instead of sucking it.
Bats may roost in trees or may inhabit caves, buildings, or any structure that provides an overhang. They are social animals, often roosting together in large swarms: one now-vanished colony of Mexican free-tailed bats (Tadarida brasiliensis mexicana), from the Carlsbad Caverns of New Mexico, was estimated to contain 9 million bats. Today, an estimated 1.5 million bats in the same species now live under the Congress Avenue Bridge in downtown Austin, Texas.
In most species, females give birth to only one offspring per year. The young are usually born naked and helpless, with small and undeveloped wings, but grow rapidly and soon can fly and forage on their own. Those bats that live in places with cold winters can hibernate during the winter. Other bats migrate to warmer climates when winter comes. Bats are remarkably long-lived for their size; both fruitbats and microbats have been known to live for over 20 years.
It should be clear by now that the reputation that bats have as evil, bloodthirsty, winged demons of the night is totally unjustified. Bats are not only elegant and fascinating creatures, they benefit humans by pollinating plants, dispersing seeds, and feeding on insect pests. Unfortunately, because of human misunderstanding, as well as practices such as habitat destruction and indiscriminate use of pesticides, many bat species are endangered, and some have already gone extinct. In the United States, nearly 40% of the native bat species are endangered.
Bat Conservation International has much more information about bat ecology and conservation. Or check out Animal Bytes, presented by Sea World/Busch Gardens, for more fun bat facts.
Grzimek, B. 1975. Grzimek's Animal Life Encyclopedia. Van Nostrand Reinhold Co., New York.


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Mexican Lucha Libre is Now a Global Phenomenon
By Anthony Zubia
More and more, people around the world are starting to notice the art and culture of Lucha Libre. This form of Mexican wrestling loosely translates to "Free Fighting," and that's exactly what it is. This near hundred year old tradition is much more acrobatic and theatrical than its American counterpart. Pro wrestling may be popular in the United States, but not many people know much about the Lucha Libre culture.
While Lucha Libre did gain some momentum in the 90s (above), jumpstart the career of a few luchadores, and reach some international exposure, this style of wrestling has never been as popular as it is now. In the current political landscape, people are starting to bring other cultures to light, and this is one of them. The latest Jack in the Box ad features a Luchador, Conan O'Brien recently traveled below the border to document this culture, and yes, there is even a Donald Trump inspired wrestler in Mexico.
Aside from people seeing this on TV or YouTube, Netflix is bringing Lucha Libre culture to an international audience. With streaming in over 90 countries, now is the time to show what this Mexican tradition is all about. Below are 3 titles you can stream now to immerse yourself in this masked culture.
This TV series is executive produced by acclaimed director Robert Rodriguez. His channel, El Rey Network, features horror movies, Kung Fu flicks, and Lucha Libre. Lucha Underground is changing the game for pro wrestling by doing something that's never been done before: making it a TV series.
In the era of binge watching, this show took a risk and changed up the way wrestling is watched. Instead of the same old trash-talking promos backstage between matches, this show digs deep into the lore of Lucha Libre. This art form is based off of the battle of Good versus Evil, so these luchadores are portrayed as masked heroes and villains with their own origins and storylines.
The matches on this show are very fast paced and filled with as much action as you can fill in a 45 minute episode. The talent on the show ranges from Mexican luchadores, wrestlers from the American independent scene, women performers who aren't confined to their own division, little people known as Minis, and Exoticos who are dressed in drag. There is really something for everyone on this show.
This documentary goes south of the border and behind the scenes with some of the top talent in Mexico. The film revolves around the luchador "1000% Guapo" Shocker and other luchadores he crosses paths with such as Sexy Star, Blue Demon Jr, and the late great Hijo del Perro Aguayo. Sexy Star is a luchadora who overcame domestic violence and is not just popular in Mexico, but in Lucha Underground as well. Blue Demon Jr is the son of the legendary Blue Demon who is considered one of the godfathers of Lucha Libre. Hijo del Perro Aguayo was innovative and popularized the violent hardcore style of Lucha Libre through his Perros Del Mal brand, but tragically passed away in the ring a few years back.
There is also an in-depth look at Mexico's top promotions that present these luchadores: CMLL and AAA. CMLL is the longest running wrestling promotion in the world, and AAA is known for taking Lucha Libre to the next level in the 90s as well as currently through Lucha Underground. It's amazing to see the spectacle of these brands and how they promote storylines, feuds, and events week after week.
Delving into the psychological aspects, Lucha Mexico also goes beyond the ring by showing what these luchadores go through. From the extensive training and conditioning, to the many injuries and doctor visits, it's eye-opening to see what these people are willing to do to achieve their dreams. Aside from the physical pain, there is a lot these Luchadores have to endure, whether it's travelling nonstop away from family, constantly being in the spotlight, losing loved ones that you work with, or even losing your mask, which represents your career, identity, and everything you've ever worked for.
TALES OF MASKED MEN
Tales of Masked Men covers the history, culture, and terminology of Lucha Libre; perfect for those who want to learn more about the art form. This PBS mini documentary also makes great points regarding Lucha's popularity and how it rivals soccer in Mexico, and notes that the idea of wearing masks dates back to pre-Hispanic times. Aside from covering these facts, this film features the tales of 3 luchadores; El Santo, Mascarita Sagrada, and Solar.
When the topic of Lucha Libre comes up, the name El Santo immediately comes after. He is considered an immortal icon of Mexico because his popularity transcended the Lucha culture and made its way into Mexican pop culture. Decades before Dwayne "The Rock" Johnson left wrestling to become a movie star, El Santo was a huge star in the ring, films, and comic books.
The second Luchador featured is Mascarita Sagrada. This wrestler is classified as a "Mini" and gained his fame during the popularity of the American cultural phenomenon that used to be referred to as "Midget Wrestling." Mascarita Sagrada overcame struggles because of his size and used it to his advantage. With his speed and quickness, Mascarita Sagrada has entertained children all over Mexico and even found a spot on the roster of the TV show Lucha Underground.
Finally, Solar is the final luchador covered. This legendary wrestler was unsure of what he wanted to do for a living until he attended a Lucha Libre show. After that, he trained, had a mask made, and fulfilled his destiny of becoming a real-life superhero. He is thankful to have discovered the culture of Lucha Libre and has been happy ever since. His lifestyle caught the attention of his son, and now tag team partner, Solar Jr. After Solar retires, he mentions it brings tears to his eyes knowing that his son will continue his legacy with the same name and mask.
Aside from Netflix, fans are able to watch wrestling from all over the world thanks to the Austin based FloSlam. Two European companies are showcasing the Mexican style of wrestling through UK's Lucha Forever and Ireland's Over The Top wrestling, which dominantly features a Lucha mask as its logo. Also featured on FloSlam is the promotion group Pro Wrestling Revolution, who at their last event scheduled the return of Ultimo Dragon, a legendary wrestler who is from Japan but started his career in Mexico through the Lucha Libre style.
While Japan has been accustomed to Lucha Libre and still appreciates it to this day, with partnerships between New Japan Pro Wrestling and the aforementioned CMLL, it's great to see this Mexican cultural phenomenon expand across the globe. For an art form that's been around for decades, it's finally getting the respect and exposure it deserves. One can only imagine what's next for this truly global phenomenon.
Latinx FilmAnthony Zubia June 2, 2017 Latinx Film, Documentary, Lucha Libre
'An Uncertain Future' and Other Short Documentaries Are Amplifying Marginalized Voices
Latinx FilmRichard Gonzalez June 9, 2017 Latinx Film, Immigrant Rights, Immigration, Short Documentary
Ovarian Psycos: The Cycling Brigade Advancing Its Own Form of Activism
Latinx FilmLatinx Spaces May 25, 2017 Latinx Film, Documentary, Activism


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I ministri della solidarietà sociale della Repubblica Italiana si sono avvicendati dal 1987 al 2001 e dal 2006 al 2008, dapprima come ministri senza portafoglio, fino all'istituzione del dicastero nel 2006.

Dal 2008 le sue funzioni confluirono nel Ministero del lavoro, della salute e delle politiche sociali, a sua volta dal 2009 scisso in Ministero della salute e Ministero del lavoro e delle politiche sociali.

Lista

Linea temporale

Note

Solidarietà sociale

redpajama_set_name: RedPajamaWikipedia


There are different forms of childcare and a childminder family is one of them. It can be a pleasant way, especially if you already know someone where you can bring your child. For example someone with the same ideas and opinions as you or someone you are very familiar with. But if you do not have anyone in your area who can provide such a shelter, you can also look a bit further. There are probably several childminder families in your area.
A childminder (also known as a childminder in Belgium) does small-scale childcare in a homely atmosphere. A childminder can accommodate a maximum of 6 children, of which 5 under 4, 4 under 2 and 2 under 1 (own children younger than 10 years are also taken into account).
A childminder must be registered in the National Register for Childcare and Playgroups. You can only register as a childminder if you are in possession of a relevant diploma, a child's first aid certificate and a VOG (Declaration on the Behavior).
Benefits of a childminder family?
The advantage of a childminder family is the more individual attention that can be given to your child, making it possible for the childminder to respond more quickly to certain signals from your child. The groups are smaller than in the regular daycare, so that everything will be a bit calmer for your child. Your child is also in a homely atmosphere, which can be experienced as pleasant. In addition, a childminder is generally somewhat cheaper (and more flexible) than a childcare center.
If you want to opt for a reception within a childminder family, there are a few things to look out for before you make a choice.
You can of course choose to have a friend fit your baby. For example grandfather, grandmother or a good friend. If you want to do this officially, they must have a valid diploma (The government has compiled a list with diplomas that are valid, to be able to work as a registered childminder.) So that they can register with a childminder agency. If they do not do this, then you can unfortunately not use the childcare allowance.
How many other children and in what age?
Whether or not a garden?
Also inform yourself about the delivery and collection times and make good agreements about it. Make good agreements about when you do / do not have to pay. What if your child is ill once or there is another reason why he can not come, why are you paid? Or not?
If the childminder family is not affiliated to a childminder agency, then you actually do not have any rights at all. You can make so many appointments with someone, but if it goes wrong or this person suddenly quits, you still have a problem. You can therefore better choose someone who is registered with a bureau.
Inform yourself about the host family you have in mind. Maybe there are people in your area who already have experience with it? Or maybe the neighbors can tell you something? Do not hesitate to inform yourself around you. You bring your most valuable asset to it anyway. After all, with your child you do not want to take unnecessary risks.
A standard rate for a childminder family is between 5 euros and 6.50 euros per child, per hour. However, there are childminder families who use a higher hourly rate, for example on the basis of their level of education, their work experience or the provision of extra services. In addition to these standard rates, there are also costs associated with registering as a questionnaire with a childminder agency. In addition, additional costs can be charged, such as a reimbursement for drinks, food and diapers. The height of this can vary per childminder family.
You can choose to have a childminder with you, in which case you can determine the hourly rate yourself. However, this is only allowed for a maximum of three days per week. Would you like it longer, then you should employ the childminder. This means that you also have to keep a payroll administration and deduct payroll taxes (and pay them).
If a childminder does not look after your home more than three days a week, then it falls under the Home Services Regulations.
If you make use of the childcare allowance, you can be reimbursed for part of the childcare costs. If the childminder provides care in the owner-occupied home, the childminder agency will carry out a "safety and health risk assessment" before registration in the National Register on Childcare.
The government imposes quality requirements on a childminder family. The municipality can instruct the GGD to check a childminder agency. Ultimately, it is important that your child is at a safe address.
This way you create more time for yourself as a mother!
Bullying - Tips for dealing with bullying!


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From the Courts
Local Vibes
Our Readers' Opinions
Bassy – Love Vine
Dr. Fraser- Point of View
R. Rose – Eye of the Needle
Dr Jozelle Miller
Independence Messages
What's on Fleek this week
Real Talk Fitness
Health Wise
Understanding the Law
Hey Rosie!
Prime the pump
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Birthday/Wedding/Anniversary
In Memoriam/Acknowledgement
Interactive Media Ltd
Police extend the lifting of the ban on the playing of amplified music
The lifting of the ban on the playing of amplified music has been extended to August 31, 2020.
The ban, which came into effect on March 26, 2020 was lifted on July 10 for an initial period extending to July 31, 2020. This has now been extended to August 31.
"To this end, every person(s) applying for such permission must comply with all of the protocols relating to the prevention / containment of the spread of the COVID -19 virus; including the newly developed and adopted "Recommendations for the Managed Conduct of Mass Gatherings with or without Amplified Music" issued by the Health Services Subcommittee of the National Emergency Committee/COVID 19 Task Force; Ministry of Health, Wellness and the Environment," a release from the police said.
The Government of St. Vincent and the Grenadines has declared August 3rd and 4th, 2020 as public holidays.
"It therefore means that Vincentians will be enjoying an extended weekend. Accordingly, the RSVGPF strongly advises every citizen and visitor, that whatever you choose to do over this long weekend, please do it in a safe and responsible way. When you adhere to the protocols, you are protecting yourself and those around you; thereby helping to contain the spread of the Corona Virus."
62 new COVID cases recorded today, January 19
The number of active COVID-19 cases in St Vincent and the Grenadines continues to increase, with 62...
Teenager dies due to complications of dengue fever
A 15-year-old asthmatic female has been recorded as the eighth person to die from complications of...
Kingstown Fishmarket closed for sanitization
The General Public is pleased asked to note that the Kingstown Fishmarket will be closed during the...
SVG may not receive COVID-19 vaccines before June – Gonsalves
IT APPEARS THAT the Covid-19 vaccinations to be provided for 20 per cent of the population through...
Chief Medical Officer (CMO), Dr Simone Keizer-Beache
Local Covid spike cannot be termed community spread – CMO
by BRIA KING LOCAL HEALTH AUTHORITIES have objected to the World Health Organisation's (WHO)...
JESTINA POMPEY
Sister of Spiritual Baptist Archbishop is SVG's first of two Covid-related deaths
ST VINCENT and the Grenadines (SVG) has recorded two COVID-19 deaths in the last four days. The...
Searchlight newspaper
Churches among the five local clusters of infection
Investigation shows positive individuals broke isolation
Donald Trump exposes America
Red glow coming from volcano is natural, no evacuation order given
SVG NINE MORNINGS FESTIVAL 2020 COMPETITIONS RESULTS
Forty-six new Covid-19 cases reported in SVG
Sagicor surprises new Moms with Gifts for the New Year
Boyfriend dumped me because I didn't have threesome with his friend
BRAGSA renovates Bequia Fish and Vegetable Markets
Interactive Media Ltd. • P.O. Box 152 • Kingstown • St. Vincent and the Grenadines • Phone: 784-456-1558 © Copyright Interactive Media Ltd.. All rights reserved.


Don't know what to do with a car you cannot get rid of? Call Jordan's Auto Salvage and we will pay you top dollar to take it away.
Our company purchases used autos to sell at affordable prices. We also have a growing inventory of salvageable auto parts. All vehicles and parts can be purchased directly from our website. Parts are priced to sell (not including shipping costs) and can be picked up, shipped or delivered.
Freight shipping is available at buyer's expense and is calculated using weight and buyer's zip code. Please e-mail or call us for shipping costs or other payment options.
All purchases made through our website (not including shipping or delivery costs) are due IN-FULL at time of checkout. Shipping charges must be received BEFORE shipment is made.
Auto purchases made other than through our website require a $100.00 deposit. Balance is due upon receipt of auto.
Part purchases made other than through our website require a 20% deposit for orders under $100.00. Balance is due upon receipt of part. If parts are to be shipped, full payment including shipping costs will be necessary BEFORE shipment.
Copyright © Jordan's Auto Salvage. All Rights Reserved.


Our Junior Demonstration Team performed at the Opening Ceremony of the National School Games at the Jurong East Sports Hall on February 1st, 2013. The ceremony also saw Chelsea Sim of Aljunied Taekwondo Club and Bryan Yap of INDUK Taekwondo representing 'Taekwondo' in the athletes' oath-taking ceremony.
Click here to view the event.


Contact our 24-hour emergency towing services @ 717-577-8920 today.
Turn to us when you need excellent auto and cycle maintenance and repair services in York, PA. You can expect us to do everything to keep you on the road with our all-inclusive auto care services. Get 5% OFF on repairs if you're a Memorial Hospital employee.


Newcastle has an opening for a full time addition to our Maintenance Department. Successful candidate will have experience in potable water supply/distribution, waste disposal, commercial heating/ventilation/AC, pneumatic/hydraulic systems, low voltage controls, communications, fire warning/suppression, commercial dishwashing/laundry equipment, medical gas supply, etc.
This position maintains equipment, machinery, and physical structure of the hospital/manor.
Includes upkeep of grounds, disposal of trash and waste materials, may also work with our In Home Services Department to perform services under their program, such as lawn maintenance, snow shoveling, and other outdoor maintenance for clients in their homes. Minimum starting pay $15.20 DOQ.


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Lainey Wilson Reflects on Her Road From Impersonating Hannah Montana to Singing on the Opry
Olivia Ladd
Getty Images for BBR Music Group
On Valentine's Day, Lainey Wilson made her Grand Ole Opry debut. By that time, she'd hustled for nine years to find a foothold in the music industry, and it was always a dream of the Louisiana native's to make it into the Opry circle.
Wilson's whole family was present for the big moment, and the experience was so awe-inducing that it left her in tears.
"The first time I went to the Grand Ole Opry, I was nine years old. I remember exactly where I was sitting in the crowd. We saw Bill Anderson, Little Jimmy Dickens [and] Crystal Gayle. I just remember looking up there, being like, 'Man, I wanna do that,'" Wilson remembers. "When I stepped foot in that circle, it was all over. I just started crying."
It was just after that first trip to Music City that Wilson wrote her very first song and picked up the guitar. The path to her dreams before Nashville stardom included singing in church, playing in a country cover band in clubs around Louisiana, Arkansas and Mississippi, and a stint as a Hannah Montana impersonator.
The latter turned out to be useful experience when Wilson landed a spot opening for the Hot Country Knights, Dierks Bentley and his band's '90s country band. She felt right on par with their irreverence and exploration of their alter egos.
"I think Hot Country Knights started off as a joke, and now it has just become this big ol' thing," Wilson told The Boot during the 2020 Country Radio Seminar in February. "It's a place where people can go and have fun and be silly. I'm all about that."
Under the guise of comedy country, Hot Country Knights booked a trek with all women openers. Though the One Knight Stand Tour was canceled due to the COVID-19 pandemic, the band has, in interviews, been vocal about the lack of women on country radio; they've also dueted with Terri Clark, on their song "You Make It Hard," and covered songs by the likes of Shania Twain and Reba McEntire, the latter of whom Wilson was also slotted to share a stage with this year.
Wilson did manage to make it out on one tour this year, although it was cut short. The self-described "bell-bottom country" artist joined Justin Moore and Tracey Lawrence for a run of shows prior to the pandemic temporarily shutting down the concert industry.
"They had to personally approve me to open up the show, and to know that they liked my stuff enough to let me get up there before them is pretty wild," Wilson admits. "I've gotten to see how much work goes into the big production like that. It makes so many people to make the wheels spin. I didn't realize that."
Who Is Lainey Wilson? 5 Things You Need to Know
Filed Under: Editor's Picks, Lainey wilson
Categories: Country News, Exclusives


The modeling of turbulent two-phase flows is a subject of interest both to those who wish to understand and predict natural phenomena (e.g. clouds, tornadoes, volcanic clast dispersion, etc.) and those who wish to design and optimize engineered products (combustion devices based on fuel-spray injection such as gas turbine engines or spark ignition engines, augmenters in military aircraft, spray coating whether for painting or for protection against pests, consumer-product sprays such as those dispensed in cans, medical sprays, etc.). Despite the considerable range of applications and the substantial monetary advantages of successful prediction of turbulent two-phase flows, and despite numerous studies addressing modeling of these flows, there is still a lack of consensus for simulating these flows. The results described below are in the context of volumetrically dilute two-phase flows in which the volume of the condensed phase is negligible with respect to that of the carrier gas (e.g. O(10^(−3))) although the ratio of the condensed-phase mass to that of the carrier gas mass can be a substantial fraction (e.g. O(10^(−1))) because the density of the condensed phase is larger by a factor of O(10^3) than that of the gas.
© 2011 Springer Science+Business Media B.V. This work was conducted at the Jet Propulsion Laboratory (JPL) of the California Institute of Technology, and was sponsored by the U. S. Department of Energy and the U. S. Air Force Office of Scientific Research under an agreement with the National Aeronautics and Space Administration. Computations were performed on the SGI Origin2000 at the JPL Supercomputing Center.


Hi Guys, apologies for the silence on the blog the past month, I have been so distracted by a lot of projects, ideas, business plans that my creative juices literally stopped flowing. But in the next few posts I plan on bringing you all up to speed on everything: from my skin going crazy, to my nails just deciding they'd had enough and also that I am now #TeamNatural. There's a lot to share and I will start off with this post talking about new products that I have added to my skincare routine.
When I started blogging, I literally would try out any and every skincare product, and my skin could take it…. or so I thought. Fast forward to mid-last year when I mistakenly used an expired makeup product on my face and it's just been downhill from there. Then I had these extremely painful stress pimples towards the end of the year as well, so my skin has pretty much been in recovery mode since the start of 2017. Which is why I haven't really shared as many makeup looks as I used to, or even talked much about skincare because I have just been trying to figure it all out. I still am to be honest, and I am also very very careful what skincare products I now use. But clearly I am not careful enough, because I had a mini breakout just a week ago after trying out a serum someone raved about…lol. See why I don't like talking about skincare and products, even I can't seem to get it right.
OBVIOUSLY, I am a now lot more cautious when it comes to skincare products, I may even go as far as saying I am not willing to try anything new at this point. These products by Clarins are for the body, so I was willing to try them out. I recently attended a 'Bare Beauty with Clarins' event put together by the Beauty Bar and we were taken through a few products in the Clarins range.
Regular readers will know that I am a huge EXFOLIATION advocate. You MUST exfoliate your skin at least twice a week, to get rid of the dead skin and also remember to wear SPF daily (how I exfoliate). I typically use loose scrubs because I think they are more effective and I don't have to deal with the 'film' left behind when you use cream/gel based scrubs. However, I am just not a huge fan of the mess that comes with using loose scrubs. If I currently had the bathroom/shower of my dreams, they wont be a problem, but right now, with my current situation (bathroom) they just aren't convenient. This scrub by Clarins is the perfect balance, I apply to wet skin work it in all over and then I go over it with soapy exfoliating mitts. I am definitely loving this scrub and with my method, there's not a 'film' in sight.
This is currently my all-over-body moisturiser, it's light and melts nicely into the skin. I especially love the fact that it's got SPF20 in it, I'd been using a body lotion with SPF50 just on the parts of my body that get the most exposure to the sun i.e. my arms, my shoulders, my décolletage and my neck and then some regular body-butter (from Bath & Body Works) over the rest of my body. But now I use this Brightening Body Veil all over my body and then still layer my SPF50 lotion over my arms, neck and decolletage. I will share more about the SPF50 lotion and my sun-blocking combination in another post.
Honestly with the way my skin has been going, I've only just managed to get it under control and my current skincare routine seems to be working just nicely so… I don't particularly feel like trying out any new products at the moment.
Instead, I have decided to giveaway this Clarins Bright Plus HP Intensive Brightening Smoothing Serum to one of you guys. The Giveaway is open to Lagos residents only, and you must be able to pickup from a location on the Island.
I will randomly pick a winner over the weekend.
Previous Post #TGiFREEMANICURES IS BACK!
As an aside: Have you tried diet to fix your skin break outs? Diary and gluten elimination along with staying off new products till your skin settles down. I'm currently on the whole 30 and it's working like magic.
ALSO: If you find out why your nails have had enough, please let me know, mine just started unusually breaking (and they are about your length- so much confuse) so I had to cut them because- Tired.
Tbh skincare can be so tricky sometimes. Glad your skin is getting back because I always admired your skin.
I really want to try Extra-Firming Day Wrinkle Lifting Cream of Clarins.
Yeepeee….just started with clarinet multi hydrant, it makes me feel confident.i tink it's d best of ol, thou i was shortly introduced.tnx to my bae?


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New Bumblebee Camaro for "Transformers: The Last Knight"
The teaser for the next installment from the Transformers series has been released. Directed by Michael Bay, the production of "Transformers: The Last Knight" starts this month and is expected to feature Mark Wahlberg in the lead along with Anthony Hopkins.
Now, everyone's beloved Bumblebee has been an integral part of the Transformers' story from the beginning. For the latest installment, the character has been upgraded to a sixth-generation Chevrolet Camaro. The car features a unique bodykit with a wide front splitter, a highly revised front end, skirts and a spoiler at the back, all wrapped in Bumblebee colors.
Transformers: The Last Knight is due to release on June 23, 2017. Check out the first teaser below and keep watching this space for more updates.
Transformers: The Last Knight teaser:
Related Topics:2016 Camaro, Bumblebee, Teaser, Transformers
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Q: Exception while running dll made from jar in .NET I have a requirement wherein i have to make dll using IKVM from jar file.
This jar file contains code related to java.security APIs i.e. Signing and verifying files.
When i am trying to execute this dll in my .net framework environment.
The exception which I am getting while signing process is :
java.security.KeyStoreException: PKCS12 not found
        at java.security.KeyStore.getInstance(KeyStore.java:616)

My code where it is failing is :
FileInputStream fileInputStream = new FileInputStream(keyStorePath);
            KeyStore keyStore = KeyStore.getInstance("PKCS12");
            keyStore.load(fileInputStream, password);

While verifying also my code is failing at the below part:
InputStream inputStream = new FileInputStream(KeyFilePath);
            CertificateFactory certificateFactory = CertificateFactory.
                    getInstance("X.509");
            X509Certificate x509Certificate = (X509Certificate) certificateFactory
                    .generateCertificate(inputStream);

As per my understanding PKCS12 and X.509 is native to java and won't work directly.
Please let me know if my understanding is correct and help me resolving it.

redpajama_set_name: RedPajamaStackExchange


"Franklin Young" is a stub article. You can help our fellow visitors by expanding it! A stub is a page that doesn't have enough information regarding the subject. Stub pages can be easily expanded by doing research on the topic and editing the page.
Franklin Young is a writer for PAW Patrol. He has written a few episodes of the show, and has written episodes for other shows such as Reda Kai and Justin Time.


text:
#ifndef CMD_HADNLERS_MAILS_H
#define CMD_HADNLERS_MAILS_H

#include <cmd_handlers.h>

/*!
 * This handler will be return info about mail
 * */

class CmdHandlerMailInfo : public CmdHandlerBase {

    public:
        CmdHandlerMailInfo();
        virtual void handle(ModelRequest *pRequest);
};

REGISTRY_CMD(CmdHandlerMailInfo)

/*!
 * This handler will be send mail by admin
 * */

class CmdHandlerMailSend : public CmdHandlerBase {

    public:
        CmdHandlerMailSend();
        virtual void handle(ModelRequest *pRequest);
};

REGISTRY_CMD(CmdHandlerMailSend)

/*!
 * This handler will be list of mails
 * */

class CmdHandlerMailsList : public CmdHandlerBase {

    public:
        CmdHandlerMailsList();
        virtual void handle(ModelRequest *pRequest);
};

REGISTRY_CMD(CmdHandlerMailsList)

#endif // CMD_HADNLERS_MAILS_H