Or if I wanted them fully upholstered. I actually like the look of the exposed frame just a tiny bit more but when it comes right down to it, I just don't think it's possible to do that on my chairs because the cane backing is attached so closely to the edge of the frame. In order to cover up the cane backing, there would only be about 1/2-inch of frame exposed on the sides (perhaps less if I use piping), so that kind of defeats the purpose.
But that's okay, because I really do like the look of a fully upholstered chair also. And I came across two pictures that really made me excited about the possibility in my dining room. The first one was this dining room, with the gorgeous raspberry dining chairs with the white piping, tufted backs, and white buttons.
Here's a closer view of those same chairs in that dining room.
Of course, those chairs are a very different shape from my chairs. But then I came across this dining room by one of my favorite designers. Its the same concept, and the shape is closer to that of my chairs. So you can picture a tufted back on these rectangular back chairs with the solid coral fabric and white piping.
But anyway, on to the fabric. I ordered the solid coral fabric for my side chairs. It's Richloom Forsyth Coral. The color on that website isn't accurate at all. Mine looks a bit more accurate to me, but the color is pretty much exactly the color that the buffet used to be.
For the host chairs, I decided to go with a combo of the Richloom Anamarie Aspen fabric and the Robert Allen Run Along Sunburst, both of which are on sale for 60% off right now. I still plan to build my own host chairs, with the floral fabric wrapped around the back and sides, and the other fabric used for the seat and front of the back — basically the areas that will receive the wear and tear.
So that's the plan! Fabric has been ordered, and things are moving forward.
Sounds like a plan. I agree about the floor length skirts. I can envision cat hair clinging to the bottoms plus they get dusty. Love the fabrics, wish there was a bigger picture of the floral. I love the pattern and the colors. I think you made a good choice. Will be a lot of work, but worth it in the end. Have fun. PS had I known you HATED brass lamps, I never would have mentioned them.
Those three. Fabrics look great together. Can't wait to see everything put together.
Super excited to see the process on the chairs, I love learning new techniques from you! Any progress on the outside of the house yet?
No progress yet. The weather has been pretty rainy and/or windy for what seems like weeks now. April is generally pretty wet here, so it might be May before I can get anything done to the exterior. The problem is that I read that after a rain, you should give the house three days to dry before painting, and I think it'll take me at least three days to paint. I don't think we've had that many dry days in a row (that weren't either really windy or too cool for this Texas girl to spend lots of time outside) in about six weeks now. Hopefully May will be a bit dryer so that I can make some progress outside.
Good morning Kristi. Happy to see your post this morning. I'm just trying to recap your vision so far to see if I'm following it correctly. The fabric you just ordered/purchased is for 6 side chairs & the 2 host chairs that came with them will be placed on each side of the buffet that is now black. (love it). They will be in the solid coral. You are going to build 2 new host chairs with cordinating fabric. The table is now white with gold trim. You are going to have floor length black/white horizontal striped drapes. Did I get it right? Trying to I vision it in my head. I thought we were going to see drapes this morning, but I remember you said you hated to sew. Wish I had your talent. I was also hoping to see buffet with both lamps. I loved seeing the finished projects. I know you probably sometimes feel over whelmed & have to stop to regroup, so please don't feel like I'm trying to rush you. I just love seeing the finished work. I started following when you moved the old kitchen cabinets around and it turned into a remodel.
Really love your fabric choices and they seem more 'you'. Can't wait to see it all come together with the chairs being upholstered. They are going to look stunning. IMHO, whilst I love the look of full skirts on chairs, I just don't think they are practical at all, especially when you are cleaning the floors, peoples shoes against the fabric etc. I know when I've sat in chair with a full length skirt, I felt very uncomfortable and didn't know where to put my feet, as I didn't want to put my shoes against the fabric. Make sense? Again, IMHO, I think the short skirts look kinda frilly and a bit old fashioned. Looking forward to seeing your progress as always.
I discovered you thanks to Marigene, and I really enjoy your blog. I am a big fan of Tobi's work too, and I think your dining room is going to look fabulous. I have subscribed your blog, because I want to make sure I don't miss any!
That doesn't look like embroidery on those chairs to me. I'm guessing it's that flat cording like what you'd see on mariachi pants, and you definitely have the skills to sew that on yourself.
I hadn't thought about the cording, and I think that's right! Looks just like the cording/piping on the rest of the chair.
I love the long skirts, but I agree about the practicality. It's one of the things I hated about puddled drapes.
Another thought is that pattern could be painted onto the fabric very easily and can still look nice, and i know that is something you know how to do. Great job so far, I love the fabric choices.
I love your fabric choices. Very pretty. I too love a spot of embroidery on the back of dining chairs. Tres chic! You might try a sewing machine retail store that sells embroidery machines to find someone to do your machine embroidery. Here in the Pacific Northwest it would be Quality Sewing and Vacuum. There are so many people who have embroidery machines that I think you wouldn't have any trouble finding someone to do your job. Also, where did you find your fabrics…especially with such a good sale? Keep up the good work. I know it can be daunting but just look at how far you have come.
Looking forward to seeing you put this all together. You have me eyeballing my horrible oak dining room chairs and wondering what I can do with them! I definitely see them in a different light (transforming them rather than replacing them) thanks to you!
Love your choices!! This room is really going to make a statement upon entering your home!
I love that floral fabric. I can't wait to see the end result. Will you be posting a tutorial on how you build the chairs? I learn so much from you! It would be fantastic if in your spare time (hahaha) you would put on some workshops to teach your many skills to some of us lesser talented/skilled individuals. I would certainly travel the 650-ish miles to learn from you.
Agree with Mary Anne's cat hair comment. The navy blue skirted sofa we used to have was always covered with cat hair. I used Roomba extensively though and I think that made it worse. Our Roomba, Wanda, seemed to end up pushing the hair ahead of her and it always stuck to the skirt.
The fabrics are so pretty all together. Once again, you are teaching me to step out of my comfort zone, mixing colors and fabrics to end up with a sophisticated look. I can't wait to see a finished chair!
Love your choose in fabric for both chairs. And when finished they will be stunning. This area is coming together beautifully. And you must be very happy now with your chooses.
Just amend my comment on flat cording. I think you can get a nylon type and burn the end so it won't ravel. Attach using fabric glue (tack in place, maybe?) and then sew on to secure. I'm sure there are tutorials so that you could make it come out perfectly.
Adding—- Suddenly getting pop up ads on your page. I close them, but there's an annoying video one in the middle of your post that I can't eliminate. Just thought I'd mention.
I am not meaning to be rude or mean in any way, but I just can't get on board with your new plan. I was so getting the black and white stripes with that other floral and white walls, green tabel etc. you had going on before. It was bright and clean and vivid. So I'm disappointed you have dropped it cuz I loved it. Maybe when it's all done I will get it, but for now, no sir, I'm not digging it. But I wish you all the best and sincerely hope that YOU love it cuz in the end that's all that matters.
Great fabric choices. The dining room is going to look amazing!
I'm sure when all is said and done it will be beautiful (your work always is), but I'm having a bit of heartbreak over covering the cane and destroying the sweet finials on your dining chairs. I love their unique and airy look and will be sad to see that lost. The photos of upholstered chairs you're posting are also nice, but they seem more generic and therefore less exciting to me. But I guess I'll just have to get over it; After all, it is your dining room 🙂 and I know it will be great.
I know. Those cute little finials. 🙁 You have no idea how much time I've spent staring at those chairs, trying to make it work with leaving the frame exposed. I just can't seem to make it work. I'm sad to see the little finials go, but hopefully when all is said and done, I won't regret it.
If you decide to go the embroidery route, Darlene at Embroidme San Antonio could help you out. She does great work!
Hmmm, I'm kind of surprised at your choices. They seem so… tame and traditional. I love the colors in the floral, but I thought you were going for something more modern and bold, with black incorporated.
Oh well… looking forward to seeing what designs you settle on for the chairs.
those chairs! I hate to see you cover up those cute finials! Just wondering if you would somehow remove the caning and use fabric and batting covered boards that would insert into the space where the caning was. You wouldn't lose those details! However, without being there to see how the chairs are assembled I have no idea how you would get those panels to stay put! Like I tell my husband, I'm just the idea person, logistics is his department 🙂 Keep up the great work! I love seeing what you're up to!
Love those coral chairs in the inspiration photo. I know the long skirts would be covered with cat hair HERE (and snags!). If you can't find someone to embroider the white trim, what about soutache braid? Just a thought. I can't wait to see how everything comes together.


Minimum of 1 year Front Office experience in a 4 or 5 star hotel.
Diploma or equivalent; major in Hospitality or Tourism preferred.
Fluent spoken and written English, Cantonese and Mandarin. Other foreign languages an advantage.
Handle all guest check-ins and check-outs in a clear, organized and courteous manner.
Process guest reservations when Room Reservations office is closed.
Control room assignments and allocate appropriate room to each guest.


VOP CZ participated at the FUTURE FORCES military technology fair.
On Friday, March 1, 2019, it was pleasure to welcome Mr.Lubomir Metnar, Minister of Defence of the Czech Republic.
VOP CZ employees completed the reconstruction of the SU-100 self-propelled gun, one of the legendary Soviet machines that served in World War II.
At Prague Letna we saw a military technique that underwent repairs or modernization in our company.
VOP CZ has signed a new service contract for repairs of Main Battle Tanks in the amount of CZK 450 million.
Thank you for your cooperation in the past year and wish you and your loved ones a joyous Merry Christmas and a successful step into 2019. Whether accompany you health, happiness and success.
Congratulations to the Army Logists for the 25th anniversary of the foundation. We are glad we could be there.
This weekend, the NATO Days of Military Parade took place. Our business has been traditionally along with other state-owned enterprises a partner of this event.
We introduced our advanced technologies at the 8th of International Defence Exhibition IDEB 2018 in Bratislava in mid-May.
VOP CZ signed a significant Service Agreement with ARQUUS (formerly RENAULT Trucks Defense (RTD) in mid-May at IDEB 2018, the International Defence Exhibition in Bratislava.
NIMR Automotive and VOP CZ launch strategic partnership at IDEX 2017.


text:
The Writer, 25. sējums
lished in Womankind, of Springfield, Ohio. For years after that she was too busy to think of writing, but after the family moved to Pittsburgh she started in to get experience and to " learn how." She did space work on the Pittsburgh Dispatch and Pittsburgh Gazette-Times for about a year, and then tried the magazines, and her stories. came back and back and back — though generally with letters, in place of rejection slips, begging for stories on cheerful, merry themes. But as Mrs. Johnson says, she has. spent her life helping people to die, or trying to make them live, and writing stories about doll babies and pink clouds and tame cats does not come natural to her, for as she puts it, she has seen life too naked. "When you once get down," she says, "to the bed-rock of primitive emotions hunger, thirst, lust of life, hate, greed of possession - it is hard to write pretty stories. My stories aren't cheerful. I know they aren't. How could they be ? If I ever succeed, it will be because there are editors bold enough to publish a woman's real thoughts, instead of the polite ones she ought to think." Besides. the story in Lippincott's, Mrs. Johnson has had a story in Young's Magazine, and one in Holland's Magazine, published at Dallas, Texas, and the March Lippincott's will contain another of her East Indian stories.
Annette Thackwell Johnson, who tributed the story, "The Churail," to Lippincott's Magazine for February, was born thirty-six years ago in India, where her father had gone as a civil engineer under the British government. While there he became converted and entered the American Presbyterian Mission. Her mother was the daughter of the moderator of the General Presbyterian Assembly. When Mrs. John
was five years old she was brought "home," and visited Scotland and Oxford, Ohio, but her seventh birthday found her back in India, where she spent the seven years. Then she
sent to the south of England, to Lancaster in Cornwall. After remaining here for a little more than a year she went to Lille, in the north of France, where she spent nine months. Her parents then sent her to Wooster, Ohio, and she attended college there for four years, when she married Frank Orr Johnson and, at the age of twenty, returned to India as a missionary's wife. With her husband she spent six years and a half in India, just at the end of the terrible famine, going through plague and cholera, and ending up at the Sabathen Leper Asylum. Then, as their little boy was almost dying of malaria, they came to America. Mr. Johnson was soon called to be pastor of the Shield's Presbyterian church in Sewickley Valley, Pennsylvania, and was there spring he entered the Episcopal church and is now rector of Christ Church, Pittsburgh. Mrs. Johnson says she always thought she could write. At boarding school she used to keep the girls up nights telling them stories, and while she was at college she wrote some short stories that were pub
Ralph Roeder, whose story, Sunset Island," was printed in Iarper's Magazine for February, was born in St. Louis twentynine years ago, and is now a practising lawyer in that city. His earliest literary work was done at the age of thirteen, when he wrote and published several very thrilling novels, designed for a schoolmate who frequently devoured the regular printed supply he brought with him several hours before school was out, and then made hurry calls on Mr. Roeder to supply the deficiency. Later Mr. Roeder edited the paper at the Central High School in St. Louis, and when he attended Washington University he contributed to the monthly there. His work now is done in the intervals of his law practice, and he has had stories in the Youth's Companion, Collier's, Adven
years. Last
ture, the Semi-Monthly Magazine Section, Young's Magazine, several magazines of the Munsey group, and in other publications, including a series of legal stories in the New Story Magazine. His first story was accepted at a good price at the first place to which he sent it.
that it gave a final kick, not however at its creditors, and retired from the prosaic world to its native Hesperian Groves." Mr. Springer then began contributing to the Sunday Section of the San Francisco papers, the News Letter, the Argonaut, the Pacific Monthly and Sunset Magazine, both in prose and in verse. He did a series of lyrics for John Metcalf, the composer of " Absent," and other songs, which were published by Schmidt and Company. He also wrote a number of lighter lyrics for various vaudeville singers, and a vaudeville sketch of his has been produced in New York. In 1911 Mr. Springer, with his wiie, leit San Francisco to loaf along the West Coast, through Mexico and Central America, and write up Panama for Sunset Magazine, and their article appeared in Sunset May, 1912, number. Since coming New York, Mr. Springer has been a literary free lance, and since then has had articles in the Smart Set, Adventure, Young's Magazine, the Cavalier, the Black Cat, the Semi-Monthly Magazine Section, and Lippincott's.
Fleta Campbell Springer, who had a story, * Wild Oats," in Harper's Magazine for February, is the wife of Thomas Campbell Springer, also a writer of short stories. Mrs. Springer was born in Kansas, and spent her early years in a little frontier town in Oklahoma, forty miles from the nearest railway. The family then moved to Texas, and later to Cautornia, where her father, John H. Campbell, was a practising attorney until recently, when he engaged in the business of grape-growing in central California. Her mother has been all her life interested in educational work, and is the founder of an organization in California for the bringing together of teachers and parents of school children, which is the only one of its kind in existence and which has had a phenomenal success. While living in California Mrs. Springer contributed articles on various subjects to western magazines and newspapers. A year ago she began writing fiction, and her first short story, " The Solitude," was printed in Harper's Magazine for March, 1912. This was succeeded by stories in various magazines, and Mrs. Springer is now engaged on a novel.
PERSONAL GOSSIP ABOUT AUTHORS.
" Tom
Fielding. — The solenin banning by the Doncaster free library committee of "Tom Jones" reminds one that the publisher's Reader who first recommended Jones " for publication was a woman.
Andrew Millar, to whom the manuscript was submitted, handed it over to his wife, as his custom was with all the lighter kinds of literature. The good lady read it and advised her husband not to let it slip through his hands on any account.
On the strength of her recommendation Millar offered Fielding $3,000 for the manuscript.
a good sum in those days, and Fielding had not expected to get half as much. Villar, however, had no cause to regret his bargain. "Tom Jones " profited him to the extent of $90,000, out of which he made presents to Fielding to the value of $10,000. — London Special in New York Sun.
Glasgow. – Until two years ago Miss Ellen Glasgow could work only in her home
Thomas Grant Springer, who wrote the story, Moses and the Rock," which was printed in Lippincott's for February, is a Californian, hailing from San Francisco. He comes of a family of printers, his grandfather having published one of the earliest Caliiornia inland papers, later being elected state printer, in which office Mr. Springer's father succeeded him. After some early experience in the newspaper business, Mr. Springer, with Adam Hull Shirk and Albert Schertzer, published a magazine called the Satyr, concerning which he says : "The Satyr kicked its heels joyously for six months, being regularly "roasted' on its appearance, and as gaily responding. After
woman who has been highly successful. She has always interested me.
" These books will not deal with problems. I do not ever let a problem get into my novels - there is none, except, of course, as some problem of an individual life may present itself to the character. I concerned with any propaganda. A book should never serve any purpose but the teliing of life as it is — being faithfully realistic.
And realism is only the truth of life told, and is the writer's true business. Hawthorne was strongly realistic. He did not try to be pleasing or pleasant. He wrote things as he saw them."—New York Evening Post.
in Richmond, Virginia. Now she lives and writes almost entirely in New York city.
"I have just finished a book," she said. "I must go rather slowly about writing. I cannot write more than one book in two years. That is not very many – I cannot understand how any one can finish and publish two books a year regularly. It seems that one ought to give more of one's self to a book than that. For my own work, I should like to write each novel and keep it ten years before I publish it. But my friends tell me : 'Of course that is impossible. You change so much in ten years all would be different. You would be obliged to write it all over again.' I suppose that is true.
"I don't find it best to write about people or places when they are immediately before
When I first came to New York, to live here for a time - it was two years ago - I expected to be here for six months of the year perhaps, and to do most of my work in Richmond. Actually, it turns that I am now here about nine months of the year, and spend one month in Richmond. Even at the time I worked altogether there, however, I did not write the things immediately about me. One really must get at some distance and obtain a perspective, especially for realistic writing. I believe strongly in the realistic novel, but realism is n't a photographic reproduction of life. It is rather the truth of life portrayed - and in the novel, with an interpretation, for one must put one's self into the writing. In my present book, everything is taken wholly from actual life; it had all been in my knowledge and thoughts for ten years or more.
" All of my novels have been cast in the South. In this last book of mine, two or three chapters are set in New York city. My idea was to tell the life story of a woman in the transitional period — the book begins in 1884 in the South. The years since then have been the period of transition — the change has come in that time from the old to the new.
"I have in my mind the stories of seva eral women," she said. "I want to write several books, each taking the liie story of one woman and working it out. I want to tell for one thing the story of the business
Hutchinson. A. S. M. Hutchinson, who has scored his second big success with " The Happy Warrior," began writing about eight years ago, when he was a medical student ; but his ambitions lay in another direction, and he did not drift into journalism — he deliberately walked into it. "I always intended to earn my living with my pen," he says, "and took the plunge when I had about one short story, two articles (for Punch), and some verses (ior Scraps) accepted. I did not know a soul who had the remotest connection with literary work, but I was — and have been — frightfully lucky." Mr. Hutchinson wrote all manner of things all day long for three months or so ; some of them attracted the notice of the publishers of Pearson's Magazine, and he presently obtained a place on their magazine staff. For a while he was assistant editor of the Royal Magazine, then co-editor of the Rapid Review. Then he made another plunge"; he cut himself adrift from editing with a good practical knowledge of what the magazines require, "thanks to the pains that had been taken with me," he remarks, " by P. W. Everett, Pearson's Magazine editor." He cut himself adrift simply because he wanted to make headway in other fields, and, hearing that the Daily Graphic wanted a leader-note writer, he sent in some specimens and secured that appointment. During this period he wrote " Once Aboard the Lugger"; as soon as it was finished he found a publisher for it without difficulty, and it was immediately and widely successful.
In the same year (1908) he was appointed night editor of the Daily Graphic, of which he has recently been made editor.
Mr. Hutchinson devoted four years to the writing of "The Happy Warrior," partly because he had very little leisure, chiefly because he took the most laborious pains with it. He could have published it two years ago, but it did not satisfy him, so he set to and re-wrote it from start to finish. "It was a dreadful task," he sighs. "Some of the scenes in it have been written a horrifying number of times, but I found, when the thing was done, that, so far from tiring of it, I had grown uncommonly, fond of Percival and the rest of the characters." -New York Times Review.
CURRENT LITERARY TOPICS.
Henry James's Later Style. - The "later manner of Mr. Henry James," according to a critic in the Publications of the Modern Language Association, is far inferior to his earlier manner. In revising "Roderick Hudson," for instance, Mr. James is apt to substitute a general word or phrase for a particular one. Thus, the older text reads in one place: "It would have made him almost sick, however, to think that on the whole Roderick was not a generous fellow." In the last edition this becomes: "It would have made him quite sick, however, to think that on the whole the values in such a spirit By were not much larger than the voids." the same process, a transparent brown eye" reappears as "a transparent brown regard." Formerly, Roderick "looked at the straining oarsmen and the swaying crowd with the eye of a sculptor"; now he looks at them "with the eye of an artist, and of the lover of displayed life." Then Mr. James substitutes for the natural word a word which is commonly used in a somewhat different sense, as when he alters "I shall be better entertained" to "I shall be better beguiled." Sometimes this change provides the reader with a puzzle, as in the sentence: "She had already had a long colloquy with the French chambermaid, who
had published her views on the Roman question." The fact is that this chambermaid was not so learned as these words would imply, but that Mr. James has merely employed the word "published" in the sense of "expounded."
French idiom seems to have a marked effect upon his later style. Christina remarks: 'She's capable of thinking that, mamma," where mamma is not a word of address, but a noun in apposition with "she." Another example occurs when the phrase, "paying, to Rowland's knowledge, his first compliment," is changed to "acquitting himself, to Rowland's knowledge, of his first public madrigal." Here we have, not the English use of "acquit," but the equivalent of "s'acquitter de." Mr. James is even guilty of altering "said it was very promising" to "pronounced it tremendously trouvé," and of changing no fixed day" to "no fixed jour." He is also given to increasing vagueness. In the first edition of
Roderick Hudson" there is an admirable directness, as in the sentence: "During the dreary journey back to America, made, of course, with his assistance, there was a great frankness in her gratitude, a great gratitude in her frankness." This is diluted in the revised edition into the statement that "she had used him, with the last rigor of consistency, as a character definitely appointed to her use." A gem of this sort of revision is the transformation of " shaking his hunting whip with little quick strokes" into "still agitating, in his mastered emotion, his implement of the chase."
He "Said." The technique" of the present day short story writer embraces a curious error in observation and judgment, set forth precisely in the advice of a successful novelist to aspirants: Never use the phrase "He said," "She said," etc., where any ingenuity or invention can produce a substitute. Other couplings must connect the dialogue.
The advice evidently is based on rule 44 or rule 109, or some such, of the short story writer's technique. In one interesting tale by a writer of much popularity there may be
says he,"
found consecutively these substitutes : "Offered Fleecer," acquiesced the colonel," " calculated Fleecer," "argued Cordelia," " frowned Fleecer," "triumphantly bated Cordelia," "earnestly advocated Georgia," "laughed Jim," " enthused Cordelia," 'acknowledged Jim" — and at last a lone " said."
The substitutes endeavor to present the mood of the speaker, it is true, but the fact has been overlooked that the eye of the reader, which takes the phrase "he said " without a glance, may become fascinated by the variation. The result is the precise opposite of that intended. It causes the " couplings " to stand out conspicuously – finally to the detriment of the dialogue.
Mackellar," said the young lord in " The Master of Ballantrae," "I am now a very happy man." And thereafter follow with periect abandon "said I,"
says 1," "asks my lord," said I," said he," said 1," etc.
The eye must hunt for them, it so accepts the probability of their being there. The construction is submerged. In the modern technique it is crying aloud like a kicked pup. The older generation used "he said " and she said " as if they were well-ordered walks along which the dialogue might go without hitch and without interruption. The modern regards them as offenses against invention, monotonously reiterative, and overlooks the apparent fact that the reader who makes no ado at all of them, if they be seen at all, is likely to find himself, in the case of the ingenious substitute, observing with curiosity the cement in which the sentences are set, and not at all the sentences themselves. Chicago Tribune.
The Art of Writing. – Writing is a crait, and the first requisite is to have a good and flexible syntax. The great difference between two writers of more or less equal imaginative or intellectual powers, one of whom is beginning to write while the other has had a good deal of practice, is that the latter will find his sentences land on their feet like cats as soon as he throws them out. It is possible to acquire this facility, and
certainly imitation of writers with an agrecable rhythm, in whose hands language is a pliable instrument, is a means to achieving it. But, unfortunately, rhythm is a personal property ; it expresses the mood of the writer almost as clearly as his choice of words, and it is fatal to acquire the manner of another man which is unsuited to the aspect in which things actually appear to ourselves. Imitation is therefore a unless we are careful to choose for imitation an author who sees more or less eye to eye with us — and then there is a danger of becoming a mere echo. -- Desmond McCarthy, in the Eye Witness, London.
Trainlog Newsparer Mea. To a writer for the Newark Evening Star Robert A. MacAlarney, associate professor in the Columbia School of Journalism, showed an examination paper for copy readers, prepared for pupils in the school, with questions like these :
" What is the real aim of a newspaper head ?
"What is an insert ? What is 'B' copy, 'C' copy, etc. ?
" What do you mean when you say 'write me three sticks on this'?
"Write the top-deck of a head, with any labeling you think necessary.
'When handling copy for an 'extra' what is the chief thing to be born in mind ?
What does the word 'alleged' accomplish in the way of saving your face when you handle a dangerous (from a libel standpoint ) story?
" As a copy reader, how do you regard the sworn testimony against prisoners taken: in a magistrate's court ?
What is a 'follow' story and a 'follow'. head?" Partic'ilarly interesting was this :
Given Helen Gould's limousine crashing. into the automobile of John D. Rockefeller, with both owners occupying their cars, but neither badly hurt, which name is the more important in writing the head? Why? Given the bulletin of the crash, stating that neither
more than shaken up, and that both cars managed to proceed under their own:

redpajama_set_name: RedPajamaCommonCrawl


Though the ordination of women has been hotly debated in a number of churches (and in particular in the world-wide Anglican Communion) there has been a strange silence on the subject from academic theologians. "They have left the debate," says the author of this book, "for the most part, to the also-rans."
Without Precedent seeks to examine the arguments that, in the absence of serious academic contributions, have been advanced. In particular it looks at claims of ancient precedent for modern practice. What did Jesus think about women? Was Paul a misogynist or a feminist, a reactionary or a revolutionary? Does the role of Mary of Magdela, in scripture and tradition, offer any guidance (as many have claimed)? Were there female priests, and even bishops, in early Christianity?
Extravagant claims have been made and repeated in all of these areas, and have crucially influenced decisions taken. This book provides, in the words of former Archbishop of Canterbury, Rowan Williams: "a lucid and helpful survey, which quite rightly punctures some awful historical nonsense."
"I read it with appreciation for its clarity and comprehensiveness. It is undoubtedly a lucid and helpful survey, which quite rightly punctures some awful historical nonsense."
"This elegant survey will no doubt cause quite a stir, and rightly so."
"Disagree though I may with Geoffrey Kirk's final position, I must strongly recommend this sparkling volume on women's ordination to the priesthood. Dr. Kirk skillfully engages the pertinent Scriptural texts and historical record, and witheringly exposes the largely flabby arguments still making the rounds in church debate. Along the way, he uncovers logical missteps and conceptual failures that have littered the discussion. This is a book that will make reflection wiser and more honest, and finally, one hopes, more faithful to the integrity of our Christian common life."
Geoffrey Kirk read English Literature and theology at Oxford and was for many years National Secretary of Forward in Faith, a campaigning group in the Church of England opposed to the ordination of women. He was an Anglican parish priest and in 2004 entered the Catholic Church.


I am very happy to inform you that university of Calicut has launched School of Drama & Fine Arts at Dr John Matthai Centre, Aranatukkara Thrissur.
The School of Drama and Fine Arts (formerly School of Drama) started in 1977 by Prof. G Sankara Pillai and the classes started form 1978 with only 3 year degree course (BTA). Now offers Bachelor in Theatre Arts (BTA), Master in Theatre Arts (MTA), M Phill / Ph.D Integrated course etc. The courses in Drama is designed as practical oriented and residential. Writing, Acting, Children's theatre, Direction, Technical designs etc are the major departments of play production. Apart form regular classes, varieties of practical workshops are conducted by the experts in the field of Television, Cinema, Traditional acting methods, Yoga, Martial arts etc.. Major plays are presented as the part of practical study. This is the only centre in south India conducting "Foreign students placement programme". Calicut University Little Theater (CULT) is a repertoire company that has been attached to School of Drama.


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text:
Revamped Mega Millions Begins After Virginia Ticket Mix-Up
The first draw under the new Mega Millions rules took place last night, but a technical issue in Virginia meant that some players were sold tickets for the old number matrix and left with no chance of winning the jackpot.
What Went Wrong in Virginia?
The Mega Millions changes included the number of main balls being reduced from 75 to 70, with the number of Mega Balls increased from 15 to 25. The Virginia Lottery, however, accidentally sold 323 tickets under the old format, with the previous price point of $1 per line rather than the new $2 cost.
The glitch involved 628 lines, including 182 which had a number greater than 70, making it impossible for those ticket holders to win the jackpot. Depending on the Mega Ball drawn, all the remaining lines may also have been left with no chance of winning. As it turned out, the winning Mega Millions numbers on Tuesday were 6, 28, 31, 52 and 53, with Mega Ball 12.
Virginia Lottery Apology
The Virginia Lottery has apologised for the mistake and pledged to honour all tickets sold during the disrupted time frame. John Hagerty, a spokesperson for the lottery, said: "We've been working to get the word out to those Mega Millions players because it's important for every ticket to have the same chance of winning a prize. Even though relatively few people are impacted, we want them to know that all of those tickets can be refunded along with the price of a new ticket, and any prizes won will be honoured."
Nobody won Tuesday's Mega Millions jackpot, which stood at its new minimum value of $40 million, but hundreds of thousands of players across America picked up prizes. Take a look at the World Lottery Results page for more information.
Fans of the game can now look forward to the next draw on Friday night, when the jackpot will be up to $48 million. Tickets can be bought online from authorised retailers in participating states, or numbers can be chosen online.
Article Published: Wednesday, 1 November 2017 10:13:47+00:00
Article Last Modified: Tuesday, 6 November 2018 15:54:43+00:00
Author: Lewis Rutledge


Kurdish (کوردی, Kurdî) is a continuum of Northwestern Iranian languages spoken by the Kurds in Western Asia. Kurdish forms three dialect groups known as Northern Kurdish (Kurmanji), Central Kurdish (Sorani), and Southern Kurdish (Pehlewani). A separate group of languages, Zaza-Gorani, is also spoken by several million Kurds, but is linguistically not Kurdish. Recent (as of 2009) studies estimate between 20 and 30 million native speakers of Kurdish in total. The majority of the Kurds speak Kurmanji.
Windfuhr identified Kurdish dialects as Parthian, albeit with a Median substratum.
Northern Kurdish (Kurmanji) is the largest dialect group, spoken by an estimated 15 to 20 million Kurds in Turkey, Syria, northern Iraq and northwestern Iran.
According to Encyclopaedia of Islam, although Kurdish is not a unified language, its many dialects are interrelated and at the same time distinguishable from other Western Iranian languages. The same source classifies different Kurdish dialects as two main groups, northern and central. The reality is that the average Kurmanji speaker does not find it easy to communicate with the inhabitants of Suleymania or Halabja.
Gorani appears to be distinct from Kurmanji and Sorani, yet shares vocabulary with both of them and some grammatical similarities with Sorani. Hewrami, a dialect of Gorani, was an important literary language since the fourteenth century but was replaced by Sorani in the twentieth.
European scholars have maintained that Gorani is separate from Kurdish and that Kurdish is synonymous with the Kurmanji-language group, whereas ethnic Kurds maintain that Kurdish encompasses any of the unique languages or dialects spoken by Kurds that are not spoken by neighboring ethnic groups.
Gorani is often classified as part of the Zaza–Gorani branch of Indo-Iranian languages. The Zaza language, spoken in the northernmost parts of Kurdistan differs both grammatically and in vocabulary and is generally not understandable by Gorani speakers but it is considered related to Gorani. Almost all Zaza-speaking communities, as well as speakers of another closely related language spoken in parts of Iraqi Kurdistan called Shabaki, identify themselves as ethnic Kurds.
Today, Central Kurdish is an official language in Iraq. In Syria, on the other hand, publishing materials in Kurdish is forbidden, though this prohibition is not enforced anymore due to the civil war.
Before August 2002, the Turkish government placed severe restrictions on the use of Kurdish, prohibiting the language in education and broadcast media. The Kurdish alphabet is not recognized in Turkey, and the use of Kurdish names containing the letters X, W, and Q, which do not exist in the Turkish alphabet, is not allowed. In 2012, Kurdish-language lessons became an elective subject in public schools. Previously, Kurdish education had only been possible in private institutions.
In March 2006, Turkey allowed private television channels to begin airing programming in Kurdish. However, the Turkish government said that they must avoid showing children's cartoons, or educational programs that teach Kurdish, and could broadcast only for 45 minutes a day or four hours a week. However, most of these restrictions on private Kurdish television channels were relaxed in September 2009.
In 2010, Kurdish municipalities in the southeast decided to begin printing water bills, marriage certificates and construction and road signs, as well as emergency, social and cultural notices in Kurdish alongside Turkish. Friday sermons by Imams began to be delivered in the language, and Esnaf provided Kurdish price tags.
The state-run Turkish Radio and Television Corporation (TRT) started its 24-hour Kurdish television station on 1 January 2009 with the motto "we live under the same sky". The Turkish Prime Minister sent a video message in Kurdish to the opening ceremony, which was attended by Minister of Culture and other state officials. The channel uses the X, W, and Q letters during broadcasting.
^1 Just as in many English dialects, the velarized lateral does not appear in the onset of a syllable. Additionally, in some dialects, the velarized lateral /ɫ/ changes to a [ɾ] in women's speech.
^2 /ɫ/ and /ɡ/ are strongly palatalized before the close and mid front vowels (/i/ and /e/) as well as the rounded high front allophone [ɥ] of the phoneme /w/, closing on /t͡ʃ/ and /d͡ʒ/.
^3 In the Kurmanji dialect, a phonemic distinction is made between aspirated and unaspirated voiceless stops. Thus /p/ contrasts with /pʰ/, /t/ with /tʰ/, /k/ with /kʰ/, and the affricate /t͡ʃ/ with /t͡ʃʰ/. This may be an areal feature shared with languages such as Armenian.
As in most modern Iranian languages, Kurdish vowels contrast in quality; they often carry a secondary length distinction that does not affect syllabic weight. This distinction appears in the writing systems developed for Kurdish. The four "short" vowels are /ɛ/, /ɪ/, /o/, and /u/. The five long vowels are /aː/, /eː/, /iː/, /uː/ and /ʉː/. Variations occur, e.g. in Southern Kurdish where long vowel /ɑː/ is used instead of /aː/ and short vowel /ɡ/ is used instead of /ɛ/.
Všm, Vhm -šm, -hm -šm, -xm -v (-w) -šm, -hm -šm, -hm *šm?
mêzer "headband/turban" Miθra "binding", "god name" *Miça "god name"(Old Persian) mitra "headband, turban", mitre "belt, turban" metat' "to sew, to tack" *mei- "to tie"
The bulk of the vocabulary in Kurdish is of Iranian origin, especially of northwestern Iranian. A considerable number of loanwords come from Semitic, mainly Arabic, which entered through Islam and historical relations with Arab tribes. Yet, a smaller group of loanwords which are of Armenian, Caucasian, and Turkic origins are used in Kurdish, besides some European words. There are also Kurdish words with no clear etymology.
↑ Only very rough estimates are possible. SIL Ethnologue gives estimates broken down by dialect group, totalling 31 million, but with the caveat of "Very provisional figures for Northern Kurdish speaker population". Ethnologue estimates for dialect groups: Northern: 20.2M (undated; 15M in Turkey for 2009), Central: 6.75M (2009), Southern: 3M (2000), Laki: 1M (2000). The Swedish Nationalencyklopedin listed Kurdish in its "Världens 100 största språk 2007" (The World's 100 Largest Languages in 2007), citing an estimate of 20.6 million native speakers.
↑ Hammarström, Harald; Forkel, Robert; Haspelmath, Martin; Bank, Sebastian, eds. (2016). "Kurdish". Glottolog 2.7. Jena: Max Planck Institute for the Science of Human History.
1 2 "Languages of the Middle East". Archived from the original on 18 January 2012. Retrieved 23 December 2011.
1 2 A Modern History of the Kurds: Third Edition - David McDowall - Google Books. Books.google.com. 2004-05-14. Retrieved 2012-12-18.
↑ Demographic data is unreliable especially in Turkey, where the largest number of Kurds reside, as Turkey has not permitted gathering ethnic or linguistic census data since 1965; estimates of ethnic Kurds in Turkey range from 10% to 25%, or 8 to 20 million people.
↑ "Kurmanji". Retrieved 24 February 2016.
↑ "Kurmanji Kurdish" (PDF). Retrieved 24 February 2016.
↑ Allison, Christine. The Yezidi oral tradition in Iraqi Kurdistan. 2001. "However, it was the southern dialect of Kurdish, Sorani, the majority language of the Iraqi Kurds, which received sanction as an official language of Iraq."
↑ "Kurdish language issue and a divisive approach - Kurdish Academy of Language".
↑ Gernot Windfuhr, ed., 2009. The Iranian Languages. Routledge.
↑ Paul, Ludwig (2008). "Kurdish language I. History of the Kurdish language". In Yarshater, Ehsan. Encyclopædia Iranica. London and New York: Routledge. Retrieved 28 August 2013.
↑ Professor Garnik Asatrian (Yerevan University) (2009)."Prolegomena to the Study of the Kurds", Iran and the Caucasus, Vol.13, pp. 1–58, 2009 Published in 2009, Iran and the Caucasus, 13, pp.1-58.
1 2 3 Philip G. Kreyenbroek, "On the Kurdish Language", a chapter in the book The Kurds: A Contemporary Overview. The book is previewable at Google Book Search.
1 2 D.N. MacKenzie, Language in Kurds & Kurdistan, Encyclopaedia of Islam.
↑ Archived 1 May 2008 at the Wayback Machine.
↑ Edmonds, Cecil. Kurds, Turks, and Arabs: politics, travel, and research in north-eastern Iraq, 1919–1925. Oxford University Press, 1957.
↑ Ibn-Waḥšīya, Aḥmad Ibn-ʿAlī (1806). Ancient Alphabets and Hieroglyphic Characters Explained: With an Account of the Egyptian Priests, Their Classes, Initiation, and Sacrifices. Translated by Joseph von Hammer-Purgstall. Bulmer. p. 53. Retrieved March 28, 2013.
↑ Repression of Kurds in Syria is widespread, Amnesty International Report, March 2005.
↑ "After 52-year ban, Syrian Kurds now taught Kurdish in schools". 6 November 2015.
↑ "Special Focus Cases: Leyla Zana, Prisoner of Conscience". Amnestyusa.org. Retrieved 2 December 2011.
↑ "Kurdish performers banned, Appeal from International PEN". Freemuse.org. Retrieved 2 December 2011.
↑ Karakaş, Saniye (March 2004). "Submission to the Sub-Commission on Promotion and Protection of Human Rights: Working Group of Minorities; Tenth Session, Agenda Item 3 (a)". United Nations Commission on Human Rights. Archived from the original (MS Word) on 2007-06-28. Retrieved 2006-11-07. Kurds have been officially allowed since September 2003 to take Kurdish names, but cannot use the letters x, w, or q, which are common in Kurdish but do not exist in Turkey's version of the Latin alphabet. [...] Those letters, however, are used in Turkey in the names of companies, TV and radio channels, and trademarks. For example Turkish Army has company under the name of AXA OYAK and there is SHOW TV television channel in Turkey.
↑ "Turkey to allow Kurdish lessons in schools". Aljazeera. 12 June 2012. Retrieved 12 June 2013.
↑ "Neighboring Kurds Travel to Study in Iraq". Npr.org. 9 March 2005. Retrieved 2 December 2011.
↑ Turkey to get Kurdish television Archived 13 May 2006 at the Wayback Machine.
↑ "TRT HABER - Özel Kürtçe Kanala Yeşil Işık". Trt.net.tr. 28 November 2011. Retrieved 2 December 2011.
↑ "On trial for speaking Kurdish". ANF-Firatnews. 11 May 2011. Retrieved 12 June 2013.
↑ "Kurdish TV starts broadcasting in Turkey". Kurdmedia.com. Retrieved 2 December 2011.
↑ ". Number of resident population by selected nationality, mother tongue in 2009" (PDF). Retrieved 9 April 2015.
↑ "Table 4.1.1 Population by individual ethnic groups" (PDF). Government of Kazakhstan. stat.kz. Archived from the original (PDF) on 27 February 2012. Retrieved 9 July 2012.
↑ Haig, Geoffrey; Yaron Matras (2002). "Kurdish linguistics: a brief overview" (PDF). Sprachtypologie und Universalienforschung. Berlin. 55 (1): 3–14. Retrieved 27 April 2013.
1 2 "The Kurdish Academy of Language - Unified Kurdish Alphabet - IPA". Retrieved 14 April 2012.
↑ "The Kurdish Academy of Language - Unified Kurdish Vowel Phonemes". Retrieved 14 April 2012.
↑ "The Kurdish Unified Alphabet". www.kurdishacademy.org. Retrieved 2 December 2011.
↑ "The Gospels in Kurdish in Armenian characters, 1857, Constantinople". Google.com. 2010-02-18. Retrieved 2014-03-02.


text:
Dolphin snot might play a crucial role in echolocation
(AP/Wilfredo Lee)
By Rachel Feltman
Rachel Feltman
You might think it's funny, but it's snot! Okay, sorry. I'm really sorry. Please don't leave.
Aaron Thode, a research scientist at the Scripps Institution of Oceanography in San Diego, believes he's uncovered the key to the high-pitched "clicks" that make dolphin echolocation possible. And, well, it's snot.
It's thought that dolphins create their high-pitched sounds — such as signature whistles used to communicate and clicks used to "see" the ocean via echolocation — by forcing air through nasal passages beneath their blowholes. Their nasal passages contain the dorsal bursae, lumps of tissue that smack together and vibrate to produce sound. But the exact mechanics behind the diverse set of chirps and whistles a dolphin can make remain murky.
[There's something fishy about that viral image of what dolphins 'see']
"It's kind of a mystery how you can make ultrasonic sound without metal, just using soft tissue," said Thode, who presented his as-yet-unpublished research this week at the 171st meeting of the Acoustical Society of America. He was noodling around with ideas for the artificial production of these noises when he came up with an idea for how to model the process.
Along with his father, retired physicist Lester Thode — who was recruited because "he was getting a little restless" — Thode adapted a simple computer model of human vocal cords to fit the physics of dolphin nasal pathways. The model was simple, he said, basically converting the vocal system into "a bunch of legos connected by string".
When they converted the vibration of their simulated blocks and string into sound, the results were a good match for dolphin recordings. The model made a loud thump followed by a long ring, which are the two distinct halves of a dolphin's signature click. The thump, Thode said, happens when the dorsal bursae collide, and the ring is created by lingering vibrations after they pull apart.
[Hong Kong's majestic 'pink' dolphins may be in grave danger]
But to get the highest frequencies of a typical dolphin call, the Thodes found, he needed to make things a little sticky.
"When these surfaces bounce, they need to stick together for just a moment," Thode said. And a dolphin's natural mucus seems like the most obvious solution to that sticky situation.
The paper still has to be submitted for peer review, so other acoustical scientists and oceanographers will have to wait on the data before they can weigh in on Thode's findings. And while Thode and Thode plan on continuing the project with the support of the US Navy Marine Mammal Program — and hopefully studying some actual dolphins full of actual mucus – it might be tricky to prove their hypothesis.
[Watch Patrick Stewart explain why whales need snot-collecting robots]
"We're predicting that there has to be this mucus, but directly observing it will be difficult because the timescale it happens on is very short," Thode said. Things that happen in fractions of a second are hard enough to observe when they don't occur all up in the delicate nasal folds of a slippery, powerful animal. Still, they're brainstorming possible observation techniques with other researchers.
In the meantime, Thode thinks the study is a great example of the things one can do with a computer model – even one so simple it's basically a digital pile of legos and string.
"The value of a model isn't always its ability to replicate reality," he said. "Sometimes it just has to make you ask the right questions."
Endangered baby dolphin dies after swimmers pass it around for selfies
Scientists use gold nanoparticles to study the stickiness of snot
Ship noises could hurt endangered killer whales, study finds
This bizarre sea monster shows how strange life gets after an apocalypse
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Rachel Feltman Rachel Feltman is now an editor at Popular Science Magazine.
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text:
Artist colors dreams through painting
What Inspires Me: 'Art is all about experimentation'
Artist colors dreams through painting What Inspires Me: 'Art is all about experimentation' Check out this story on poughkeepsiejournal.com: http://pojonews.co/1Rm98eT
Bradley McBride For the Poughkeepsie Journal Published 4:00 p.m. ET Jan. 13, 2016 | Updated 4:01 p.m. ET Jan. 13, 2016
Bradley McBride with his self-portrait in progress.(Photo: Courtesy photo)
"I dream of painting and then I paint."
This quote by Vincent Van Gogh really defines me. Painting has been a frequent visitor in my life. In high school, my senior project was "Fauvism." I had to produce at least three oil paintings and write a 25-page essay. The movement focused on applying bold brushstrokes and vibrant color to capture reality. At the project's conclusion, my works were exhibited at the MFA in Boston.
I then took an artistic vacation for two decades.
I continued to visit museums, dabble in charcoals and study impressionism. To be a serious painter, both your heart and mind have to be in the right place. A year ago, I felt ready. My mind was clear and I felt inspired. I signed up for an adult class at Imagination Station. The instructor, Rob Bazer, challenged me to take risks and express myself. I started a new artistic journey. My style is all my own. I prefer to call it "muted impressionism" – using pastel colors for cause and effect. The beauty of art is that it is continuous and it may change from painting to painting. Art to me is all about experimentation.
The Bread & Bottle in Red Hook is sponsoring an exhibit by Imagination Station students. The students are both young and old, and a whole range of styles and subjects is represented. The beauty of painting is that there is no perfect style or subject. Two painters can view the same image and produce quite different results. There are many sides to each reality.
"The Garden" by Bradley McBride, on view at Bread & Bottle in Red Hook. (Photo: Courtesy photo)
Each artist can contribute up to four pieces. In my case, I am contributing only two. One is a self-portrait and the other is a landscape. The "Self-Portrait" is my first treatment of the subject. I wanted to build my face from an emotional palette of only the brightest colors. To create density, I added a glaze. The "Garden" offers a contrast of two different worlds. You gaze through an old, crumbly entrance way into a garden vibrant with color – reds, golds and greens. Upcoming projects include landscapes with a focus on water and churches.
The show runs through today. It is an excellent opportunity to come, mingle and share. Art is a life force. It is a break from the real world. It is hallucinatory. You can color your dreams through painting. Painting is all about recapturing your imagination.
Artwork by Bradley McBride, on view at Bread & Bottle in Red Hook. (Photo: Courtesy photo)
Hudson Valley artist Bradley McBride graduated from Texas A&M University with a bachelor's in anthropology. He works part-time at a local veterinary clinic and spends his free time writing and painting. Contact him at brad.mcbride8291@gmail.com
Read or Share this story: http://pojonews.co/1Rm98eT
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text:
Endocrine Journal
Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men
Junichiro Irie, Emi Inagaki, Masataka Fujita, Hideaki Nakaya, Masanori Mitsuishi, Shintaro Yamaguchi, Kazuya Yamashita, Shuhei Shigaki, Takashi Ono, Hideo Yukioka, Hideyuki Okano, Yo-ichi Nabeshima, Shin-ichiro Imai, Masato Yasui, Kazuo Tsubota, Hiroshi Itoh
Junichiro Irie
Department of Endocrinology, Metabolism and Nephrology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan
Emi Inagaki
Department of Ophthalmology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan
Japan Society for the Promotion of Science, Chiyoda, Tokyo 102- 0083, Japan
Department of Physiology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan
Masataka Fujita
Hideaki Nakaya
Masanori Mitsuishi
Shintaro Yamaguchi
Kazuya Yamashita
Shuhei Shigaki
Biomarker Research and Development Department, Shionogi & Co., Ltd., Toyonaka, Osaka 561-0825, Japan
Takashi Ono
Drug Discovery and Disease Research Laboratory, Shionogi & Co., Ltd, Toyonaka, Osaka 561-0825, Japan
Hideo Yukioka
Hideyuki Okano
Keio University Global Research Institute (KGRI), Minato, Tokyo 108-8345, Japan
Yo-ichi Nabeshima
Laboratory of Molecular Life Science, Department of Gerontology, Institute of Biomedical Research and Innovation, Kobe, Hyogo 650-0047, Japan
Shin-ichiro Imai
Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110, USA
Masato Yasui
Department of Pharmacology, Keio University School of Medicine, Shinjuku, Tokyo 160-8582, Japan
Kazuo Tsubota
Hiroshi Itoh
Keywords: Nicotinamide mononucleotide,	N-methyl-2-pyridone-5-carboxamide,	N-methyl-4-pyridone-5-carboxamide,	Pharmacokinetics
JOURNAL FREE ACCESS Advance online publication
Article ID: EJ19-0313
DOI https://doi.org/10.1507/endocrj.EJ19-0313
The final version of this article is now available: Vol. 67 (2020), No. 2 pp. 153-160
Published: 2019 Received: July 18, 2019 Available on J-STAGE: - Accepted: October 05, 2019 Advance online publication: November 02, 2019 Revised: -
Recent studies have revealed that decline in cellular nicotinamide adenine dinucleotide (NAD+) levels causes aging-related disorders and therapeutic approaches increasing cellular NAD+ prevent these disorders in animal models. The administration of nicotinamide mononucleotide (NMN) has been shown to mitigate aging-related dysfunctions. However, the safety of NMN in humans have remained unclear. We, therefore, conducted a clinical trial to investigate the safety of single NMN administration in 10 healthy men. A single-arm non-randomized intervention was conducted by single oral administration of 100, 250, and 500 mg NMN. Clinical findings and parameters, and the pharmacokinetics of NMN metabolites were investigated for 5 h after each intervention. Ophthalmic examination and sleep quality assessment were also conducted before and after the intervention. The single oral administrations of NMN did not cause any significant clinical symptoms or changes in heart rate, blood pressure, oxygen saturation, and body temperature. Laboratory analysis results did not show significant changes, except for increases in serum bilirubin levels and decreases in serum creatinine, chloride, and blood glucose levels within the normal ranges, independent of the dose of NMN. Results of ophthalmic examination and sleep quality score showed no differences before and after the intervention. Plasma concentrations of N-methyl-2-pyridone-5-carboxamide and N-methyl-4-pyridone-5-carboxamide were significantly increased dose-dependently by NMN administration. The single oral administration of NMN was safe and effectively metabolized in healthy men without causing any significant deleterious effects. Thus, the oral administration of NMN was found to be feasible, implicating a potential therapeutic strategy to mitigate aging-related disorders in humans.
© The Japan Endocrine Society
Endocrinologia Japonica
Edited and published by : The Japan Endocrine Society
Produced and listed by : Kyoto Tsushinsha Press (Vol.56 No.3-Vol.64 No.12) Nakanishi Printing Co., Ltd. (Vol.50 No.4-Vol.56 No.2 Vol.65 No.1-)


P3D v4 provides a new way for add-on developers to install their products. The idea is to separate the installation path of the Add-on, from the original P3D Path. This should prevent add-ons from having to be reinstalled after P3D updates. On the other Hand, this makes it more difficult to read out all installed aircrafts, because the developers are free in defining their paths. In a soon update, RealTrim Professional will automatically recognize and configure these aircraft as well. Until then, these aircraft must be manually configured. The manual below shows an example how to do it.


The famous artist Daniel Mounsey with famous fantasy Aurthor Rebecca Hayden. On the Bridge, Melbourne 2006. Friends, conspiritors, trippers.
I went to 'Liquid Architecture' last night which was most inspiring for the ears and a good workout for audio wave surfing. Hard, subtle and very cool. Experimental sound manipulation at its best.
Danke schoen fuer deinem Brief!