text:
Impact of flour fortification with folic acid on the prevalence of neural tube defects in Northern Iran
Authors: Golalipour, Mohammad Jafar | Arabi, Mohsen | Ali Vakili, Mohammad
Abstract: Several studies reported that enriched cereal grains have been fortified with folic acid to reduce the incidence of neural tube defects (NTDs). The present study was done to evaluate the impact of flour fortification with folic acid on the prevalence of NTDs in Northern Iran. In this hospital-based study conducted between March 2006 and September 2009, we screened all live births at 16 hospitals and therapeutic abortions in legal centers in Golestan province of Northern Iran. …The number of births, per 1000, affected by NTDs during the periods before (March 2006-June 2007), during (July 2007-March 2008) and after (May 2008-September 2009) folic acid fortification was assessed. NTDs including anencephaly, encephalocele and spina bifida were defined in accordance with the international classification of diseases, 10th revision (international classification of diseases-10). A total of 126 subjects with NTDs were recorded among live births (104,232) and therapeutic abortions (131) from March 2006 to September 2009. The prevalence of NTDs reduced from 1.78 per 1,000 births before fortification (95% confidence interval: 1.36 to 2.28) to 0.84 per 1,000 after full fortification (95% confidence interval: 0.60 to 1.14). The reduction rate of NTDs between before and after fortification was 52.81%. This study showed that flour fortification with folic acid is associated with a significant reduction in the rate of NTDs in Golestan province of Northern Iran. Show more
Keywords: Neural tube defects, folic acid, flour fortification, Iran
Citation: Journal of Pediatric Neurology, vol. 12, no. 2, pp. 69-73, 2014
Asymmetry of the prefrontal lobe in patients with attention deficit hyperactivity disorder: A three-dimensional volumetric magnetic resonance imaging study
Authors: Kanemura, Hideaki | Sano, Fumikazu | Ohyama, Tetsuo | Hosaka, Hiromi | Sugita, Kanji | Aihara, Masao
Abstract: Asymmetries have been reported in several regions of the brain of patients with developmental disorders such as autism, developmental language disorder, and attention deficit hyperactivity disorder (ADHD). This study focused on age-related anatomical asymmetries of the prefrontal lobe, which can be manifestations of regional specialization of systems organization where there are functional differences between the left and right hemispheres, in children with ADHD. Subjects were 7 right-handed boys with ADHD aged 6–12 …years and 5 age-matched controls. Exclusion criteria were full-scale intelligence quotient less than 80, comorbid learning disorder or developmental delay, evidence of medical or neurological disease on examination or by history, or Tourette's syndrome. No subjects met criteria for conduct disorder or oppositional disorder. Volume of the frontal and prefrontal lobes was determined using a workstation and the prefrontal-to-frontal lobe and left-to-right volume ratios were calculated. Both control and ADHD groups had a larger aggregate volume of left frontal and prefrontal lobes than of right frontal and prefrontal lobes. The leftward bias of the frontal lobe was significantly pronounced in ADHD subjects than in control subjects (P=0.026). In addition, the leftward bias of the prefrontal lobe was more pronounced in ADHD subjects than in control subjects (P=0.0041). The left-to-right volume ratio of the prefrontal lobe increased with age in both groups. The left-to-right volume ratio of the frontal lobe was more pronounced in ADHD (r=0.922, P=0.0014) than control group (r=0.521, P=0.414). In addition, the left-to-right volume ratio of the prefrontal lobe was more pronounced in ADHD (r=0.903, P = 0.0029) than control group (r=0.701, P=0.219). These findings support the argument that right-sided prefrontal structural anomalies may occur disproportionately in ADHD. Show more
Keywords: ADHD, 3-D MRI, brain volumetry, frontal lobe, prefrontal lobe, brain asymmetry, behavior
Diagnostic struggles in congenital myasthenic syndromes in children
Authors: Ekker, Merel S. | Rietveld, Anke | Kamsteeg, Erik-Jan | van Alfen, Nens | Sie, Lilian T.L. | Erasmus, Corrie E.
Abstract: Congenital myasthenic syndromes (CMS) cover a group of heterogeneous disorders in which the neuromuscular transmission is affected. We diagnosed CMS in nine unrelated patients in the Netherlands. Six mutations were discovered in the acetylcholine receptor epsilon subunit gene, two in the receptor-associated protein of the synapse gene and one mutation in dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1. We describe the diagnostic work up in these children and common diagnostic pitfalls that caused delay in …diagnosis and treatment, such as the lack of specificity of clinical features, technical drawbacks of invasive testing in young children, non-specific changes in muscle histology and false negative results of electromyography. Early initiation of treatment and alternative treatment regimens can considerably improve the quality of life of patients with CMS. Show more
Keywords: Congenital myasthenic syndrome, RAPSN, CHRNE, DPAGT1, phenotype, genotype, slow channel syndrome, acetylcholine receptor deficiency, neuromuscular junction
Guillain-Barré syndrome with pulmonary tuberculosis in a child
Authors: Chandr and, Surabhi | Momi, Harpreet
Abstract: Landry Guillain-Barré syndrome is an acute onset, progressive, bilateral symmetrical polyneuropathy of autoimmune origin. Neuropathy is due to immune attack of the peripheral nerve antigens, which exhibit molecular mimicry with the antigens of the preceding infectious agent, usually of acute respiratory and gastrointestinal illnesses. Pulmonary tuberculosis is widespread in developing countries and it is showing resurgence in the developed countries. We report a case of Guillan-Barré syndrome in association with pulmonary tuberculosis …in a 9-year-old child. Show more
Keywords: Guillain-Barré syndrome, pulmonary tuberculosis, child
Acute necrotizing encephalopathy of childhood
Authors: Rezaei, Amir | Kamali, Karmela | Haghbin, Saeedeh | Inaloo, Sorour
Abstract: Acute necrotizing encephalopathy of childhood (ANEC) is a rare form of encephalopathy characterized by rapid neurological deterioration along with seizures, decreased level of consciousness and coma. We herein report ANEC in a 12-month-old Iranian girl following febrile respiratory illness. She presented with convulsions characterized by upward gaze, spastic posture and sucking movements followed by rapid deterioration of consciousness and hemodynamic instability due to involvement of brainstem. Although several cases have been reported …from East Asian countries, it has been rarely reported from Middle East region. This is the third case being reported from Iran. The diagnosis of ANEC should be kept in mind in all children with progressive neurological deterioration following a febrile convulsion. Although neuroradiological findings might be non-specific especially in early course of the disease, brain imaging should be performed when there is suspicion regarding the diagnosis. Show more
Keywords: Acute necrotizing encephalopathy, childhood, febrile respiratory illness, brain imaging
Lamellar ichthyosis with severe vitamin D deficiency rickets and myopathy in siblings
Authors: Gowda, Vykuntaraju K. | Srinivas, Sahana M. | Seth, Preethi | Lakskman, Ramesh R. | Shivappa, Sanjay K. | Ramaswamy, Premalatha
Abstract: Vitamin D deficiency and rickets are not uncommon associations with keratinizing disorders. Children with ichthyosiform erythroderma are more prone to develop vitamin D deficiency and rickets, due to decreased exposure to sunlight, and dietary insufficiency. We report a case of lamellar ichthyosis in two siblings with vitamin D deficiency developing severe rickets and musculoskeletal features with myopathy.
Keywords: Myopathy, rickets, lamellar ichthyosis
Implications of delayed diagnosis of infantile spasms in a child with Down syndrome
Authors: Buterbaugh, Allison | Visootsak, Jeannie
Abstract: Trisomy 21, leading to Down syndrome (DS) is the most common genetic cause of intellectual disability. Approximately 1–13% of children with DS have co-morbid seizures, with infantile spasms being the most frequent type of seizure identified. Although the clinical and electroencephalography findings of infantile spasms are similar between children with DS and typically developing children, there is often a delay in the diagnosis of these seizures in children with DS. We present the case of a …male infant with DS, where the diagnosis of infantile spasm was delayed by 5 months. His case was associated with developmental regression and intractable seizure activity following diagnosis. The case highlights the implications of delayed diagnosis on treatment strategies and developmental outcomes. Show more
Keywords: Down syndrome, infantile spasms, delayed diagnosis
Clinicoradiological description of two children with hemiconvulsion-hemiplegia-epilepsy syndrome
Authors: Gowda, Vykuntaraju K. | Madivala, Bhaskar V. | Vignesh, Sukanya | Srikanteswara, Praveen-Kumar | Vykuntaraju, Sarala H. | Ramaswamy, Premalatha
Abstract: Hemiconvulsion-hemiplegia-epilepsy syndrome is an uncommon consequence of prolonged focal febrile convulsive seizures in infancy and early childhood. We report two cases of hemiconvulsion-hemiplegia-epilepsy syndrome who presented acutely and had striking neuroimaging findings suggestive of diffuse cytotoxic edema confined to one hemisphere as documented by magnetic resonance imaging, including extensive diffusion weighted imaging abnormalities in both the cases.
Keywords: HHE syndrome, developmental delay, focal febrile status epilepticus
Where did this oral tube come from?
Authors: Sohal, Aman Singh | Whittle, Victoria | Kisler, Jill


text:
Purdue Boilermakers 28, Minnesota Golden Gophers 17 - Too Little, Too Late
By Christopher Gates Oct 16, 2010, 1:59pm CDT
Share All sharing options for: Purdue Boilermakers 28, Minnesota Golden Gophers 17 - Too Little, Too Late
The Gophers are starting to fill up the stat column, but it likely won't be enough.
Adam Weber, who became the fifth quarterback in Big Ten history to throw for over 10,000 career yards in this game, has just completed a 31-yard touchdown pass to Da'Jon McKnight for a touchdown. A pass from Weber to MarQueis Gray for the two-point conversion made the score 28-17.
The Boilemakers, however, just recovered an onside kick that the Gophers had a really good shot at, and the Boilermakers will presumably run out the clock from here.
Under three minutes to go in West Lafayette, and the Gophers trail the Boilermakers 28-17 in a game that hasn't been that close.
Boilermakers 28, Gophers 17: Start The Brewster Countdown
Henry's Four Touchdowns Doom Gophers In 28-17 Loss To Purdue
Purdue Boilermakers 28, Minnesota Golden Gophers 9 - Getting Caught Up

redpajama_set_name: RedPajamaCommonCrawl


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text:
Q: Export a MySQL Database to SQLite Database Please help me with exporting a MySQL database into a SQLite database.

A: There's a fantastic Linux shell script on Github that converts Mysql to an Sqlite3 file. You need both mysqldump and sqlite3 installed on your server. Works great.

A: The answer by @user2111698 edited by @quassy works as promised. Since I do this frequently I put their instructions into a bash script:
#!/bin/bash

mysql_host=localhost
mysql_user=george
mysql_dbname=database
sqlite3_dbname=database.sqlite3

# dump the mysql database to a txt file
mysqldump \
  --skip-create-options \
  --compatible=ansi \
  --skip-extended-insert \
  --compact \
  --single-transaction \
  -h$mysql_host \
  -u$mysql_user \
  -p $mysql_dbname \
  > /tmp/localdb.txt

# remove lines mentioning "PRIMARY KEY" or "KEY"
cat /tmp/localdb.txt \
  | grep -v "PRIMARY KEY" \
  | grep -v KEY \
  > /tmp/localdb.txt.1

# mysqldump leaves trailing commas before closing parentheses
perl -0pe 's/,\n\)/\)/g' /tmp/localdb.txt.1 > /tmp/localdb.txt.2

# change all \' to ''
sed -e 's/\\'\''/'\'''\''/g' /tmp/localdb.txt.2 > /tmp/localdb.txt.3

if [ -e $sqlite3_dbname ]; then
    mv $sqlite3_dbname $sqlite3_dbname.bak
fi
sqlite3 $sqlite3_dbname < /tmp/localdb.txt.3

A gist with detailed comments can be found at https://gist.github.com/grfiv/b79ace3656113bcfbd9b7c7da8e9ae8d

A: mysql2sqlite.sh mentioned in the top post doesn't cope well with PRIMARY KEY lines, it doesn't write the trailing ) to complete the CREATE statement.
This is what I did.  I ran the mysql dump as:
mysqldump --skip-create-options --compatible=ansi --skip-extended-insert --compact --single-transaction -h<host> -u<user> -p<passwd> <database name> > localdb.txt

I then used grep to remove PRIMARY KEY and KEY:
cat localdb.txt | grep -v "PRIMARY KEY' | grep -v KEY > localdb.txt.1

I then used an editor to fix the file.  When the keys are removed you end up with a CREATE statement that looks like:
CREATE ...
  ...,
)

That trailing , has to be removed.  In vi this expression matches them, ,$\n)
Then you need to change all \' to ''
Then you can do the import:
sqlite3 local.sqlite3 < localdb.txt.1

And that's it. I haven't found a single program that worked for me. I hope this helps someone.

A: I manualy created the table structure in sqlite database.
Than I uploaded the data with teh following command:
mysqldump -u root {database} {table} --no-create-info --skip-extended-insert  --complete-insert --skip-add-locks  --compatible=ansi | sed "s/\\\'/''/g" |sqlite3 flora.db

I had to use sed to fix a different apex encoding in the two databases

A: Personally I like the simple usage of mysqldump, yet some adjustments are need (depending on your art with Unix and what you want to do).
Ex. for just one table (prods) with PK:
$ mysqldump mysql prods -u ME -pPASS  --compatible ansi --compact |grep -v "^\/\*" |sqlite3 testme2.db
$ mysqldump mysql prods -u ME -pPASS  --compatible ansi --compact |grep -v "^\/\*" |sqlite3 testme2.db
    Error: near line 1: table "prods" already exists
    Error: near line 7: UNIQUE constraint failed: prods.id, prods.ts
$ sqlite3 testme2.db '.schema'
    CREATE TABLE "prods" (
      "id" varchar(30) NOT NULL DEFAULT '',
      "ts" int(11) NOT NULL DEFAULT '0',
      "val" double DEFAULT NULL,
      PRIMARY KEY ("id","ts")
    );

For more complex things, probably better to write a wrapper, or then, use the already mentioned  fantastic awk Linux shell script on Gist .

A: The following Website has an online tool to convert
Convert MySQL to SQLite online
https://www.rebasedata.com/convert-mysql-to-sqlite-online

A: export the data with
  mysqldump database > database.sql

and import the data with
  sqlite3 database < database.sql

you may need -u (user) and -p (password) options

A: There is a fantastic, lightweight tool called SQLite Database Browser that allows you to create and edit sqlite databases. I used it to craete databases for Android apps. You can run SQL statements against it to load up the data so if you export the data from a mySQL database you can just import it using this tool. Here's a link: http://sqlitebrowser.sourceforge.net/

redpajama_set_name: RedPajamaStackExchange


Have you seen the white spots popping up in South County?
ST. LOUIS COUNTY, Mo. – Perplexed by the megapixels popping up around town? Viewers noticed the giant white circles showing up in south St. Louis County.
"Got to be happy you've got Molina out there doing his thing, Carp coming off first knocking home runs," said a driver.
Okay, so viewers noticed more how the Cardinals are doing.
But once you see these white spots, you can't un-see them.
From up above, real-life might imitate art and look like a Pac-man game. But the dots, put there by MoDOT, will help a future project take focus.
So if you see more spots showing up around the region, you are seeing things, your mind's not playing tricks with you.
"Have not noticed them," said a motorist.
Oh, you'll be seeing spots in neighborhoods, along shoulders, and in cul-de-sacs in the county, that is, unless you're hyper-focused on the Cardinals in the postseason.


text:
(thing) by Tsarren Wed Mar 08 2000 at 7:50:15
A set of drums and cymbals that can all be played by a single person. There is a bass drum (if not two) that can be played by a foot pedal, and a hi-hat cymbal that is also operated by a foot pedal and played with sticks. There is a snare drum, sevral toms, and a variety of ride, splash, and crash cymbals, all of which are also played with sticks or brushes. Playing it requires huge amounts of coordination.
(thing) by Rancid_Pickle Thu Nov 02 2000 at 22:19:39
A drum kit is a collection of percussion equipment with its associated hardware. A standard 5 piece kit contains a 22- to 24-inch bass drum, a 14-inch snare, a 13- and a 14-inch tom mounted on the bass drum shell, and a 16-inch floor tom. All measurements are the diameter of the drum heads.
As a drummer, I have to disagree with one item in Tsarren's writeup. Playing drums does not require huge amounts of coordination. A drummer needs to know how to becoms selectively un-coordinated. When you are coordinated, your hands and feet want to work together, while drumming involves doing many things independently with your limbs. As an example, a paradiddle is a series of taps in this manner:
L-R-L-L  R-L-R-R (repeat)
L = left hand
R = right hand
Using your index fingers, try tapping out a paradiddle on your desktop. Most people cannot do three in a row because their brain is trying to get the hands to work together. The brain does not want the hands to work independently. With practice, anyone can learn to become selectively un-coordinated.
Learning to play the drums paradiddle drum set 5-piece drum set
Getting your drum kit to behave soundboard Music for percussive and other atonal instruments Home Recording on a Budget: We Got the Beat
Dungeon Master's Design Kit On the Origin of Genres Satanic Zombie Cyborgs Meet the Unholy Girlfriend Danko Jones
Choochin Antler Bug October 31, 2001 How to produce drums
Learning European history from Porn Tweak UI Roland R-8 Zoo Station
The repetitive music paradox selectively deaf Drum Slang


text:
5 Chicago edtech companies making life easier for students and recent grads
by Michael Hines
Chicago is known as a hub for fintech and B2B startups, but the city is also making a name for itself in the edtech space. Many of these tech companies are working to make life as a college student or recent grad easier, whether that's through inventive student loan repayment solutions or marketplaces that make it easier and cheaper to find a tutor. Continue below to learn more about five of Chicago's most student-friendly tech companies.
PHOTO VIA CHRIS MURPHY
What they do: In addition to being heavy, college textbooks can also be pricey. RedShelf helps students save money on their books — and get more out of them. The company offers almost 700,000 digital titles for sale or rent, which are delivered on a cloud-based e-reader that lets students highlight passages and take notes, create flashcards, build study guides, and more. In addition, RedShelf offers schools an end-to-end Content Delivery System that streamlines the digital distribution process of course materials from end to end.
First things first: RedShelf has an "accessibility-first" mindset, which influences everything from product design and development to its onboarding process and approach to customer service.
What they do: Finding a tutor with flexible hours and affordable rates isn't always easy. Wyzant's platform connects students with private tutors specializing in over 300 subjects for one-on-one lessons held over video chat or in person. Users pay only for the time they need, with rates starting as low as $10 an hour. In addition to a five-star rating system and written reviews, the platform also lists the number of hours a tutor has spent tutoring in a specific subject on the platform.
Leave the cutoffs at home: Wyzant's office features a casual dress code with one exception: no jorts.
They're Hiring | View 0 JobsWyzant is Hiring | View 0 Jobs
PEANUT BUTTER FOUNDER DAVID ARONSON (FAR RIGHT). PHOTO VIA PEANUT BUTTER ON FACEBOOK.
Peanut Butter, Inc.
What they do: A 2018 Northwestern Mutual study found that millennials carry an average of $36,000 in debt, with student loans making up the majority of that figure. Peanut Butter makes it easier for millennials to pay down their educational debt by enabling companies to offer student loan assistance as a benefit. In addition to the financial benefits, the platform also provides users with personalized advice and insights, access to a loan refinancing marketplace and specially negotiated rates on debt counseling services.
What's in a name? Founder and CEO David Aronson told the Chicago Tribune that the company is named after the only thing he could afford to eat in college: peanut butter sandwiches.
They're Hiring | View 0 JobsPeanut Butter, Inc. is Hiring | View 0 Jobs
PHOTO VIA SHUTTERSTOCK
Parker Dewey
The company: Parker Dewey
What they do: Internships provide invaluable professional experience, but not every college student has the time or financial flexibility needed to take one on. Instead of asking students and recent graduates to commit an entire semester to an internship, Parker Dewey connects them to "micro-internship" opportunities. The platform's micro-internships enable students to gain professional experience working on paid, short-term projects for companies, which range from creating social media calendars to sourcing candidates and cleaning up data.
Meet the founder: Prior to founding Parker Dewey, Jeffrey Moss spent almost 20 years working as a venture capitalist.
They're Hiring | View 0 JobsParker Dewey is Hiring | View 0 Jobs
PHOTO VIA @CHANGEDAPPS ON TWIITTER
What they do: When it comes to paying off student debt, every penny really does count. That's the idea behind ChangEd, which helps users pay off their loans faster — and reduce the amount they owe in interest — by rounding up purchases to the nearest dollar and applying the spare change to their loans. The company was founded in 2016 and has processed $2.6 million in payments to date.
Big-name backer: In 2018, ChangEd appeared on ABC's "Shark Tank" and landed a $250,000 investment from Mark Cuban in exchange for a 15 percent stake in the company.
They're Hiring | View 0 JobsChangEd is Hiring | View 0 Jobs
Photos via featured companies unless otherwise noted.


When shooting the "Trust", the film crew wanted to introduce the spirits and ghosts into the plot. But the director did not agree with this idea.
And then they decided that a separate song would be written for the spirits. So this story was born.
Three days of difficult shootings demanded from children a lot of efforts and patience. But almost everything worked out.
Richard made his debut in the project, now we have a drummer and a "fire demon". Live drums enriched the song, and the fire would suffice for three clips.
We knew it would not be easy. But in practice everything turned out to be more complicated and more dangerous than we thought. Some moments of filming we captured in the next video.


Belt & Road Initiative - Nepal Thanka Exhibition, a showcase of Paubha painting has succeeded drawing attention in Beijing, the capital of China. The event organised by Art Kathmandu, Bhaktapur and China based Gorilla Fitness Centre had presented traditional Nepalese painting in silk fan giving it a Chinese touch. According to the organisers, ink water based colour is used in silk fan to paint item like dragon among others.
"The exhibition has helped providing a new dimension to the cultural relationship between Nepal and China," Kranti Kayastha, a Nepalese student who had recently completed graduation from the University of Science and Technology, Beijing said. Kayastha and along with his brother Bhusan Kayastha, also an student in China, took Chinese silk fan to Kathmandu and urged renowned Paubha artists Uday Charan Shrestha and Samundra Man Singh Shrestha to depict Nepalese traditional art over it. The artists' duo painted the Licchavi Princess Bhrikuti, considered to have been the first wife of Tibet emperor Songtsen Gampo.
"Given the art has amalgamated the tradition of Nepal and China, it is being perceived positively by the Chinese visitors," Kayastha said.
Paubha is a traditional religious painting made by the Newar people of Nepal. Paubhas depict deities, mandalas or monuments. Though Thangka is considered to be its Tibetan equivalent, Kayastha says these two genres of art have slight difference.
Historically, most of the paubhas used to feature Hindu and Buddhist deities. The trend has seen a shift in recent days with the likes of Bhrikuti, Manjushree or Buddha being prominently featured.
The exhibition that lasted for 15 days at Minsheng Financial Centre featured 26 Nepali paubha painting and six Thanka painting. Work of artists like Purna Hyoju, Deepak Joshi, Ratna Gopal Sinkhwal, Sajib Shakya, Minu Shakya and Devendra Sinkhwal was featured in the exhibition.
According to Bhusan Kayastha, the exhibition that lasted for a fortnight was successful drawing in around 800 visitors. "This is first such exhibition by Nepalese in China and we are hopeful that this initiative will help Nepalese paintings in such a big market," he added.


Marshmallow 6.0 Upgrade For Samsung Galaxy J1 .
1 Marshmallow 6.0 Upgrade For Samsung Galaxy J1 .
1.1 Samsung Galaxy j1 Marshmallow 6.0 Update Download .
1.1.1 Best Custom rom For Samsung Galaxy j1 .
Samsung galaxy j1 was launched in 2015 and since then no android lollipop update for Galaxy j1 or android marshmallow update for Galaxy j1 has been rolled out . So today in this guide we will tell you how you can update your Galaxy J1 to marshmallow 6.0 and in addition we will also give a Custom rom for Samsung Galaxy J1 .
Samsung galaxy j1 was the first smartphone in the j Series from samsung . The j Series was launhced in the budget series , Having good hardware specifications and a 4.5 inch display the Galaxy j1 became quite popular . But unfortunately being a smartphone in the budget series Samsung never updated Galaxy j1 to lollipop or Marshmallow . So in this guide today we will teach you how you can check if a Marshmallow Update is available for your Samsung Galaxy J1 or Not .
Samsung Galaxy j1 Marshmallow 6.0 Update Download .
So in this guide we will tell you how you can check if a update is available for your samsung galaxy j1 or not .
So before updating Samsung galaxy J1 to android 6.0 Marshmallow here are some points you need to remember .
There should be minimum 2Gb of storage available on your device .
Charge your phone upto 75% to avoid updating failure .
First of all turn off your Galaxy J1 for 2 minutes .
Now go to the settings of your J1 and go to About phone .
Now in about phone you will see a System Updates option .
Now you will see a " System Update is available option " Just tap on Download .
After Downloading make a reboot .
Thats All !!! You have updated your Samsung Galaxy j1 to android 6.0 marshmallow officially .
Sometime Users dont receive Update via Ota so at that time Downloading the update from official website and then flashing it .
Download the marshmallow Update for Samsung Galaxy J1 From HERE .
Now Download Odin And flash The Downloaded Firmware on your Samsung Galaxy j1 .
Before flashing via odin it is recommended to make a Backup of your full smartphone .
Best Custom rom For Samsung Galaxy j1 .
Upto now there is Only one custom rom for samsung galaxy j1 based on android Kitkat 4.4 but still it is better than the stock rom .
Unfortunately there is no android lollipop custom rom or android marshmallow custom rom for samsung galaxy j1 .
Download the Custom rom for galaxy J1 from HERE .
Now again flash the Custom rom using Odin .
Sometimes you need to download the Samsung Drivers to make the Pc recognize your smartphone , So you can download them from Samsung official website .
Note :- Flash the custom rom at your own risk , we wont be responsible for any kind of damage caused to your device .
So this was our guide on How to update Samsung galaxy J1 to android 6.0 Officially , I hope the Best custom rom for Samsung galaxy j1 solved your problem .
Can I use this rom file to update my Samsung ace J1 (SM-J110H)?


text:
Trianaea nobilis är en potatisväxtart som beskrevs av Jules Émile Planchon och Linden. Trianaea nobilis ingår i släktet Trianaea och familjen potatisväxter. Inga underarter finns listade i Catalogue of Life.

Källor

Potatisväxter
nobilis

redpajama_set_name: RedPajamaWikipedia


Malawi is committed to accelerating progress toward ending hunger and undernutrition.
To help determine how to do so, Compact2025 convened a roundtable discussion in Lilongwe, Malawi on May 26, 2016.
Malawi has made significant progress in reducing hunger and undernutrition. From 1990 to 2015, prevalence of undernourishment has fallen by more than half (from 45 percent to 21 percent), and as of 2015/16 just 4 percent of children suffer from wasting (low weight for height). Yet challenges remain, as 42 percent of children are stunted (low height for age) and 29 percent of women of reproductive age are anemic.
To address these challenges and accelerate progress, the Compact2025 roundtable discussion in Malawi brought together stakeholders from various sectors—including agriculture, social protection, nutrition, gender, water, and sanitation.
The guest of honor was the Right Honorable Vice President of Malawi and Compact2025 Leadership Council Dr. Saulos Chilima, who offered his commitment to ending hunger and undernutrition. Also offering opening remarks were IFPRI director general Dr. Shenggen Fan and the Honorable Minister of Agriculture, Dr. George Chaponda. Dr. Alexander Kalimbira, Associate Professor of Human Nutrition and Head of the Department of Human Nutrition and Health at LUANAR presented Malawi's food security and nutrition situation and recent trends.
Over 100 stakeholders from a range of sectors participated in the roundtable discussions, which focused on some of the key topics that affect food security and nutrition in Malawi, such as hunger, social protection, and vulnerability; agriculture, nutrition, and gender, and institutions and coordination.
Among the key points discussed at the meeting was the need to "break the cycle" of recurring food shortages met with humanitarian response. Participants offered suggestions for a way forward: Collect and analyze agricultural production data and Malawi Vulnerability Assessment Committee (MVAC) estimates more quickly to accelerate early action; implement the new National Social Support Programme; and make agricultural commodity policies, especially for maize, more transparent with a market-driven approach.
A scoping study was developed to inform the convening and spark discussion. It provides an overview of the current food security and nutrition challenges and opportunities in Malawi, and provides the key relevant strategies, policies, and programs in place. It also assesses knowledge, policy, and implementation gaps that impede progress. The scoping report will be updated and finalized with inputs from the roundtable discussion, and will include a preliminary plan of action.
The Malawi roundtable discussion follows similar meetings in Kigali, Rwanda and Addis Ababa, Ethiopia, Dhaka, Bangladesh. Including Malawi, these four are Compact2025 focal countries, and have committed to accelerating progress toward ending hunger and undernutrition by 2025.
Presentation on the current food security and nutrition situation in Malawi.


text:
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redpajama_set_name: RedPajamaGithub


text:
Where Are They Now: 3D-Printed Sex Toys
January 7, 2020 by Michael Molitch-Hou 3D Printing
Five to seven years ago, the key phrase "3D-printed" could hook any business idea or blogpost to the top of search engine results. Those two words would send the most trivial concept ricocheting across social media to the extent that it would end up on local news stations or into the pages of The Economist.
And it was due to this phenomenon that "3D-printed sex toy" became a hit news item, a seemingly viable startup pitch, and a possibly popular emerging trend. But did 3D-printed sex toys really take off? How feasible was the idea, really?
Circa 2012-2014, a number of sites began offering 3D printable sex toys. Though the specifics varied, there were several advantages pitched for the creation, purchase and/or use of these devices:
Discretion: Because sex toys can be 3D printed at home, there's no need to embarrass oneself by going to an adult accessory shop or even have a toy shipped in the mail with one's name on the package.
Personalization: Everybody's body is different in terms of shape, size and what's pleasurable and, as 3D printing enthusiasts know, the technology is perfect for custom one-offs.
With these purported advantages, 3D model sharing sites like Cults3D and Yeggi became populated with every variety of "sex toy" imaginable. That phrase is put in quotes because not every object described as such was meant to be used as such (such as phallic cookie cutters and "no fellatio allowed" signs).
Businesses including MakerLove.com offered a variety of free 3D printable dildo files, ranging from more standard designs to novelty shapes, like one featuring Justin Bieber's head. MakerLove in particular was financially supported via Vibrators.com, which sells bullet vibrators. These little gizmos can be placed into 3D-printed dildos to provide added functionality.
Other sites, like Dildo-Generator.com, offered the ability to design custom devices parametrically, with graphical sliders that could be adjusted to change the girth, length and shape of a 3D printable dildo model.
However, as titillating as all of these options may have been for some people, 3D printable sex toys were faced with some of the same problems that 3D-printed silverware and flatware models have seen. Anything that comes in contact with a person's insides has to be made such that they aren't prone to growing potentially dangerous bacteria.
Because 3D-printed objects are porous at the microscopic level, there are voids in which microbes can grow. Additionally, the materials from which objects are usually printed at home, like PLA, aren't necessarily designed for ingestion (though, according to MakerLove, ABS is the standard for mass manufactured plastic sex toys). That notwithstanding, the materials also almost always lack skin contact approvals not to mention the right chemical makeup and cleanliness required for internal use.
Some companies have designed food-safe filaments that are manufactured using food-safe equipment in food-safe environments using materials and additives that have been approved for contact with food. Because they have not been approved for use in sex toy production, we can't know how they would fair for such an application. However, they are likely safer than generic plastics for the fabrication of 3D-printed sex toys. Even if somehow the right approvals were obtained, one would need an autoclavable filament and a closed process that would ensure that no other matter was deposited in and on the items.
To deal with porosity, two solutions have cropped up. One can 3D print a mold for a sex toy and then fill that mold with silicone, which is generally the safest material for this and other delicate uses (such as medical devices and baby bottle nipples). The other, totally unsafe, option is for a user to sand and seal a 3D-printed device.
SexShop3D, one business that was really banking on the success of the 3D-printed sex toy industry, reported a pretty straightforward and simple method for properly sanding and sealing a printed part. After using 240 grit sandpaper to make the object as smooth as possible, a silicone spray can be used to apply three to four coats onto the device.
Despite these solutions, 3D-printed sex toys never quite took off. SexShop3D, which maintained a prominent voice in the nascent industry, seems to have ceased activity in early 2018 and the site is no longer accessible. MakerLove.com also stopped updating in 2015. Print Your Own Dick, as fate would have it, failed to launch a successful Kickstarter campaign.
A 3D-printed prototype for the Eva by Dame.
Nevertheless, 3D printed sex toys continue to be developed—just not in the way that may have been expected. One of the primary methods in which 3D printing is used is in the fabrication of sex toys is for prototyping purposes. After relying on 3D printing for prototyping its flagship product, Dame continues to manufacture sex toys and is on the second iteration of its hands-free vibrator.
An enterprising fetishist in the UK has also been using 3D printing for the design of some of the most unique sex toys imaginable, including a game of Simon Says that is hooked up to a punishment device. As the game gets more difficult, punishment becomes more likely.
New sites continue to release their own versions of custom dildo designers and companies like the New York Toy Collective are still experimenting with 3D printing. Meanwhile, the 3D-printed sex toy market may actually be thriving on Etsy, where, based on the comments left for TerribleToyShop, MadScientistCo, HappyBound, LeLuv and NerdClimax, printed products are still being shipped as of November 2019.
These more recent developments suggest that maybe the world wasn't quite ready for 3D-printed sex toys a few years ago, but that the market has been primed and is about ready to grow? Or perhaps the venue wasn't quite right and a niche marketplace like Etsy was where these designs were meant to thrive. Regardless of the cause, one thing seems to be true, people may not have been ready to 3D print their own sex toys at home and would rather have an expert do so for them.
Join the discussion of this and other 3D printing topics at 3DPrintBoard.com.
Tagged with: 3d printed sex toys • 3D-printed dildos • hype • personalization • prototyping • safety


With capacity from 10kg to 30,000kg, these vessels are available fully or partially jacketed and Insulated if required, CE marked in accordance with the Pressure Equipment Directive.
The vessels can be designed and fabricated fully in accordance with PD 5500, ASME VIII, and EN 13445.
Vessels can be equipped with propriety Agitators or Bespoke designed and manufacture in house.
Agitators range from Gate type with or without side wall scrapers to homogenisers.
Units available designed for static or mobile operation.


Architecture in Japan - do you read me?!
It documents 100 projects across nine thematic sections, including materials, models, documents, and interactive installations. Nine stories which are ultimately hypothetical ones, in hopes that they will lead to new discussions and visions for the future of Japan.


text:
Games! All sorts of different ones.
Game ideas, design thoughts, discussions, and various other bibble.
Japanese minimalism
Published by Mo on January 6, 2014 | 2 Responses
Nice blog post here by Bruno Faidutti about the trend of 'Japanese minimalism' in game design. (It's in French first, English underneath.) He says straight away that of course minimal games have existed for a while, and they don't all come from Japan. But there definitely is a strong current tradition there of games involving very small numbers of cards and no or very few other components. Faidutti suggests this is clear enough to be considered a 'minimalist school' of game design now, alongside the German and American schools (which he likens to 'classical' and 'baroque').
Of these Japanese games, I've only played Love Letter (which I don't think works very well with 2 players, but I like it a lot with 3 or more), but there are loads of other really interesting-sounding ones around. It would be nice to see more of them get European publishing before too long: or an easy way for non-Japanese readers to order them from the original publisher.
(A non-Japanese example that I've recently got hold of a proper copy (after print-and-playing it a while back) is Daniel Solis's ingenious Suspense. And Good Little Games has a load of such games free to print and play, including my own Shape Up!, which demonstrate the variety of clever and fun ideas possible.)
I picked up on what I'd seen called 'microgames' a year or so back, as first discussed here re what became Shape Up! And have bounced another couple of ideas around too, although they haven't turned into decent games (yet!) The economics of production of such games are very favourable, of course, as mentioned in this post.
As Faidutti says in the post, "Like painters, writers or chefs, most game authors dream of a pure and uncluttered design, an epitome of simplicity capturing the true essence of gaming." That partly catches the appeal, for me: but it does sound possibly a bit austere. I'd also emphasize the importance of the feeling of satisfaction gained from squeezing a fun playing experience into such a small diameter.
Posted in Card games
Dom January 6, 2014 at 8:24 pm | Permalink
I think I prefer your "microgames" label for these. Are the economics favourable, though? Obviously they're cheaper to produce in absolute terms, but what will people pay for them? I ask because in videogame design there seems to be a tendency to pay $20 for a big game, but expect small games to be $0.
Mo January 6, 2014 at 9:24 pm | Permalink
Mm, I realize here I'm somewhat contradicting what I said in that post last year. I should clarify that I don't think it's really that good for bigger publishers, as discussed in the Michael Mindes article linked from there. But the emergence of POD outlets has made a big difference to small people. The abovementioned Daniel Solis, for example, has some of his games available for free as print-and-play, but also as POD via DriveThru for prices in the $5–10 sort of range. During 2013 he sold $3300 value, earning himself $900. Now obviously he's not going to make a living on that, but the site's only been open a few months and will expect to grow, and he'll keep releasing new games onto it.
My impression is that 'physical' gamers are unlike the video gamers you cite, in that many are quite pleased to get a nice-looking bunch of objects in their hands, that they can play a game with, for 5 or 10 dollars – even if they could get a rough version of the same game for free. It might saturate out when everyone's got a drawer full of rarely-played gribble, but reviews and recommendations will probably keep good designers in interest. But I dare say that it'll still require a bigger kind of game and a big publisher for people to be able to make significant money.
Pervasive
Play-by-Web
Tabletop role-playing
Verbal games
Books Bring Your Own Bottle Cafe Casablanca Caterwaul Consequences design Dreams Fastaval Fishy Business Grenselandet Grow-type Haunted House Humour Just a Little Lovin' Knutpunkt Mixing Desk of Larp Monster Mash News None but the Brave Nostalgia Oh dear! On Location Picking up the Pieces Playtest Meetup Queen of Denial Rainbow Skyscrapers Reading Between the Lines Real Men Shape Up! Sheet Happens Small Town Folks Sport Stockholm Scenario Festival Tallinn Larp Festival The Best Medicine The Curse The Life of Mermaids The Outsiders These Are the Days of Our Lives The Smoke Thoughts Typefaces / fonts UNEXPLAINED When the Dark is Gone Women on the Verge…
Alice is Missing
Rei's Guide to Online LARP Design
Some thoughts about historical larp
Just a Little Lovin' 2019 UK
Mo on Alice is Missing
Steve Ellis on Alice is Missing
Alice is Missing on Anonymous lines and veils
Michelle Taylor on Rei's Guide to Online LARP Design
The Game Kitchen-un taller de EntreRevs 2018 – lamiradadegorgona on Starting from a blank page
Copyright © 2021 Games! All sorts of different ones.. Powered by WordPress and Spine.


text:
The Waterbury (CT) Chapter of
The Links, Incorporated
History of the Links
Waterbury Chapter Members
National Trends & Services
International Trends & Services
Services to Youth
Friendship Activities
Granville Academy
Jonathan Reed School
Community Service Project
Connecticut Food Bank Training
Chapter Meeting
Crosby High School
CT Cluster Founders Day Celebration
Chase Elementary School
40 Woodtick Road
15th National President of
Margot James Copeland and Waterbury Chapter President
A Message from our President...
Thank you for visiting the Waterbury (CT) Chapter of The Links, Incorporated website!
The Links, Incorporated, founded in 1946 by Sara Strickland Scott and Margaret Roselle Hawkins, is an organization comprised of approximately 16,000 distinguished women in 289 chapters located in 41 states, the District of Columbia and the Commonwealth of the Bahamas and the United Kingdom. Links members contribute more than 500,000 documented hours of community service annually – strengthening their communities and enhancing the nation.
The Waterbury (CT) Chapter, one of 82 chapters in the Eastern Area, was chartered in May, 1975. Whether planting dogwood trees at Waterbury's City Hall, making contributions to local families and the homeless during the holidays, or partnering with local organizations; Granville Academy, The Palace Theater, Waterbury PAL, and Girls Inc. of Western Connecticut or Waterbury schools, service to the community is paramount to our mission. Our commitment to Waterbury youth has resulted in the Waterbury (CT) Chapter awarding over $60,000 in scholarships to deserving local high school students.
Through our work with the National Kidney Foundation, the American Cancer Society and the American Heart Association, we have hosted community forums and sponsored health fairs to empower the greater Waterbury community with important health information. The Chapter is not only active in the local community but it has also focused on helping those in need in Africa. It built the first water wells in the village of Kenya and received an award along with other Connecticut Links' Chapters for building a school in South Africa called "Houses of Learning."
Over the past 44 years, the work that the Chapter has done in the Arts, Health and Human Services, National Trends and Services, International Trends and Services to Youth has made a profound impact on the Waterbury Community. As we continue to expand our programming to broaden our impact, we invite you to connect with us.
In Friendship & Service,
Adrienne Parkmond, Esq.
"You don't make progress by standing on the sidelines, whimpering and complaining. You make progress by implementing ideas." - Shirley Chisholm
Eastern Area Director of
The Links Incorporated,
Shuana Tucker Sims and Waterbury Chapter Members
The Waterbury Chapter hosted a Community Forum with Senator Chris Murphy to bring awareness to the environmental issues that impact Waterbury's Economic Development.
The Waterbury Chapter partnered with LOVE 146 to bring awareness to the issue of human trafficking.
A presentation by Shamere McKenzie who was a victim of Human Trafficking and is now a survivor and awareness advocate brought light to the issue that is impacting our communities.
© 2023 by Waterbury CT Chapter of The Links, Incorporated. All rights reserved.


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Fisherman kept $100M pearl for 10 years without realizing its worth
by Inhabitat Staff
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World's largest natural pearl
A Filipino fisherman kept this enormous pearl under his bed for 10 years without realizing it could be the largest natural pearl ever found in the world.
Palawan Island Philippines map
Many of the world's largest natural pearls have been found near Palawan Island.
Categories: Environment, News


The Protect service also helps you find lost devices.
Your phone's security is more important than ever, and Google knows it. The internet giant is launching Google Play Protect, a suite of services that helps you secure any Android device with Play Store access. The feature scans apps for threats (including relatively new risks, thanks to machine learning) and will either keep these rogue apps off of your device or remove them. It's always updating, and its relatively high visibility (see the image above) promises greater transparency into the security of your Android gear.
Protect will also help you if the worst happens and you lose your hardware. It includes Google's existing Find My Device feature (fka Android Device Manager) that will let you pinpoint, ring, lock down or wipe your device, including Android Wear smartwatches.


text:
Sections →
Diet food and fitness
Weight Loss and Diet Plans
Benign Breast Diseases
Hereditary Breast Cancers
Early Pregnancy Risks
Obesity and Diabetes
Basis of Sleep
Common Sleep Disorders
Hypertension Symptoms & signs
Benign Prostatic Hyperplasia
Penis Cancer
Carcinoma of the Anus
Exercise and Weight Control
Prevention of Clinical Diabetes
Diabetes Complications and Prevention
Male Infertility & Sexual Dysfunction
Childhood Sleep Disorders
Sleepwalking Disorder
Pediatric Obesity Prevention
Binge Eating in Children
Exercise and age
Planning for Successful Aging
Heart Attack Symptoms &Signs
Normal cognitive changes in aging
Normal Aging and Dementia
Short sleep, aging brain
Sleep speed brain aging
Blood and Lymph Diseases
Family and Pregnancy
Why preventive care is important
Remember the old saying that "an ounce of prevention is worth a pound of cure"? This can be especially true when it comes to preventive health care. Maintaining or improving your health is important - and a focus on regular preventive care, along with following the advice of your doctor, can help you stay healthy.
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Infections |
Genetic 'instruction set' for antibodies knocks down hepatitis C in mice
Sep 26, 2014 Viewed: 532
A triple-punch of antibodies both prevented hepatitis C infection and wiped out the disease after it had established itself in laboratory mice, according to a study led by Princeton University researchers. Instead of delivering the three antibodies directly, the researchers administered a genetic "instruction set" that, once in a cell, developed into antibodies that target the portions of the virus that do not mutate.
Mice treated with the antibody genetic code resisted becoming infected with hepatitis C when they were exposed to the virus, the researchers reported in the Sept. 17 issue of the journal Science Translational Medicine. The researchers also gave the antibodies to mice that already were infected and found that, in many cases, the infection disappeared to levels below detection.
Hepatitis C affects roughly 170 million people worldwide and causes chronic liver damage and cancer. The virus is transmitted to humans via contact with contaminated blood during intravenous drug use or medical procedures. Attempts to develop a hepatitis C vaccine have been hampered by the virus's ability to mutate into numerous subtypes. This genetic diversity is a barrier to developing traditional vaccines, which work by eliciting an immune response against a specific protein or other feature on the surface of the viral particle. These protein targets frequently change when the virus mutates.
To get around this problem, the researchers selected antibodies known to target parts of the virus that tend not to change during mutation, explained lead author Alexander Ploss, an assistant professor in Princeton's Department of Molecular Biology. Such antibodies are called "broadly neutralizing" because they deactivate a variety of genetic subtypes. The ones used in the study were discovered by co-author Mansun Law and his team at the Scripps Research Institute in La Jolla, California.
Rather than injecting the actual antibodies - which can be degraded before reaching their targets - the researchers injected the genetic instructions for making the three antibodies. These instructions consist of the antibodies' genetic codes, or DNA, each linked to the DNA for a benign virus called adeno-associated virus (AAV). This virus acts as a ferry that brings the antibody genes into cells, a delivery technique pioneered by co-author David Baltimore and colleagues at the California Institute of Technology.
Once inside the cells, the genetic codes were translated by the cell's machinery into hepatitis C antibodies, which were excreted into the bloodstream where they attached to the proteins on the viral surface to inactivate them.
Hepatitis C infection often has no symptoms. But your doctor may suspect you have it if you have a high level of certain liver enzymes.
Antibody Test
The first test used to check for hepatitis C infection is a blood test for the hepatitis C antibody. Your body makes this antibody when it is infected with the hepatitis C virus. The doctor can send the blood to a lab to be checked, or use a rapid test called OraQuick. The rapid test takes about 20 minutes.
If the antibody test doesn't find anything, then you probably don't have hepatitis C. But if you have been exposed to hepatitis C within the past 6 months, you will need to be tested again later to be sure.
The antibody tests are not perfect. They may show a hepatitis C infection when you do not have one. It may also wrongly show you have hepatitis C if you had it in the past and your body cleared the infection.
If the antibody test finds antibodies, your doctor will do another test called a PCR test using the same blood sample. The PCR test looks for the genetic material of the hepatitis C virus living in your body.
If the PCR test does not find anything, you might have had hepatitis C in the past and your body cleared it. Your doctor may repeat the test to be sure.
If both tests show you have hepatitis C, then you are infected and need treatment.
The investigators found that mice injected with the AAV-antibody particles went on to develop high and sustained levels of the antibodies against the virus in their blood, and these antibodies protected them from becoming infected when they were later exposed to the virus. "The treatment is a single intramuscular injection that results in high quantities of antibodies in circulation for several months," Ploss said.
The researchers also tried the AAV-antibody treatment on mice that already had a hepatitis C infection. "We weren't sure we would see any results because the antibody can only neutralize viruses that are outside of cells, whereas viral replication is taking place inside the cell, but we decided to try it," Ploss said. "The surprising thing was that within several weeks we saw a decrease in the level of virus in the blood, and in many of the mice, their virus level went below the limit of detection."
Ploss cautioned that the studies in mice would have to be replicated in human clinical trials, a step that could be a long way off. But new approaches for preventing hepatitis C are needed given how widespread the virus is in many parts of the world. Roughly eight out of every 10 people with the virus develop a chronic infection that leads to progressive liver disease and scarring. Yet most infected individuals do not display symptoms for a decade or more. A drug that came on the market in 2013 can cure the disease, but the high cost may prevent or delay widespread use, especially in developing countries.
Michael Houghton, a faculty member at the University of Alberta who, with colleagues, discovered the hepatitis C virus in 1989, said that the research by Ploss and his co-authors shows potential for developing an effective and affordable treatment for the virus.
"This work is very important since it shows that a combination of neutralizing antibodies against the hepatitis C virus can restrict viral spread in the liver thereby ameliorating, and possibly curing, chronic infection," said Houghton, who was not involved in the current study but is familiar with it. "The current work opens up the possibility of treating more patients in a less expensive way and also gives the patient and clinician more treatment options for a disease that affects 170 million people worldwide."
The study also provides evidence for the use of antibody-based strategies to prevent hepatitis C infection, Ploss said. "Much of the current research on vaccines is focused on stimulating the part of the immune system that involves T cells [which are white blood cells with a central role in the body's response to pathogens]," Ploss said, "but our study suggests that broadly neutralizing antibodies could be an important component of an effective hepatitis C vaccine."
The ability of the antibody to remove an existing infection may shed light on how the virus maintains a chronic infection in humans, Ploss said. "Our results seem to suggest that to sustain a persistent infection, the virus must continually infect new cells rather than relying on an existing set of infected cells," he said. "When we inject antibodies that destroy the viral particles, we may be breaking this chain of infection. This suggests that long-term treatment with broadly neutralizing antibodies could be effective at treating existing infection."
Because hepatitis C virus is a human infection that does not naturally occur in other animals, the researchers used two strains of mice with human-like livers that were developed by Ploss and colleagues at Rockefeller University in New York City, including the study's first author, Ype de Jong, now an assistant professor of medicine at the Weill Cornell Medical College. In one strain, the mouse-liver cells express human molecules required for viral uptake, while in the strain developed with de Jong the mice livers contain human cells.
In addition to the authors mentioned above, the study included graduate student Benjamin Winer and research specialist Sherif Gerges of Princeton University; Marcus Dorner, Michiel Mommersteeg, Jing Xiao, Kevin Vega, Rachael Labitt, Bridget Donovan and Charles Rice of Rockefeller University; Alejandro Balazs and Dennis Burton of the Ragon Institute of MGH, MIT and Harvard; Erick Giang, Justin Robbins of the Scripps Research Institute; Anuradha Krishnan and Michael Charlton of the Mayo Clinic College of Medicine, and Luis Chiriboga of New York University Medical Center.
The study, "Broadly neutralizing antibodies abrogate established hepatitis C virus infection," was published Sept. 17 in the journal Science Translational Medicine. Support for the work came from grants from the National Institute of Diabetes and Digestive and Kidney Diseases; the National Institute for Allergy and Infectious Disease (grant nos. K08DK090576, R01AI072613, R01AI099284, R01 AI10730101, and R01AI071084); the National Cancer Institute (grant no. R01CA057973); the Bill and Melinda Gates Foundation; the Starr Foundation; the Greenberg Medical Research Institute; the Richard Salomon Family Foundation; the Ronald A. Shellow, M.D. Memorial Fund; the MGM Mirage Voice Foundation; Gregory F. Lloyd Memorial contributions; and anonymous donors.
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text:
Carriera
Nativa della Repubblica Democratica Tedesca, muove i primi passi nell'atletica leggera, vincendo anche un titolo alle Spartachiadi giovanili. Passa poi al ciclismo, e già nel 1987, solo ventenne, prende parte al Campionato del mondo su strada di Villach chiudendo in 47ª posizione.

Una delle migliori velociste a cavallo tra gli anni 1990 e i primi anni 2000, ottenne decine di successi tra Europa e Nord America aggiudicandosi, tra le altre, la Coppa del mondo su strada del 2002, nove tappe al Giro Donne (sei solo nel 1995), sette Liberty Classic e due campionati nazionali tedeschi in linea.

Fu molto attiva anche nel ciclismo su pista e si laureò campionessa mondiale a Stoccarda nel 1991 e campionessa olimpica a Barcellona nel 1992 nella specialità dell'inseguimento individuale.

Ha concluso la carriera nel 2004, all'età di 37 anni, dopo due stagioni con l'Equipe Nürnberger Versicherung. Dopo una stagione da direttore sportivo della stessa formazione tedesca, dal 2006 al 2008 ha ricoperto la stessa carica per il Team HTC-Columbia Women (ex T-Mobile), formazione professionistica statunitense.

Palmarès

Strada

1987
2ª tappa Družba

1988
3ª tappa Družba

1989
5ª tappa Tour de l'Aude
9ª tappa Tour de l'Aude

1990
Stausee Rundfahrt
4ª tappa Niedersachsen-Rundfahrt
Rund um den Henninger-Turm
1ª tappa Grand Prix Postgiro
4ª tappa Grand Prix Postgiro
5ª tappa Grand Prix Postgiro
Schellenberg-Rundfahrt
1ª tappa Giro Donne

1991
8ª tappa Niedersachsen-Rundfahrt
5ª tappa Tour de la Drôme
6ª tappa Tour de la Drôme
2ª tappa Grosser Preis des Kanton Zürich
4ª tappa Grosser Preis des Kanton Zürich
5ª tappa Grosser Preis des Kanton Zürich

1992
3ª tappa Drei Tagen von Pattensen

1994
4ª tappa Volta a Portugal

1995
1ª tappa Rothmans Classic
4ª tappa Vuelta a Mallorca
1ª tappa Giro Donne
4ª tappa Giro Donne
7ª tappa Giro Donne
8ª tappa Giro Donne
10ª tappa Giro Donne
11ª tappa Giro Donne
2ª tappa Tour Cycliste
6ª tappa Thüringen Rundfahrt
3ª tappa Masters Féminin

1996
3ª tappa Tour de l'Aude
Liberty Classic
4ª tappa Giro del Trentino-Alto Adige/Südtirol

1997
9ª tappa Street-Skills Cycle Classic
4ª tappa Vuelta a Mallorca

1998
6ª tappa Street-Skills Cycle Classic
Liberty Classic
5ª tappa International Challenge
2ª tappa Tour Cycliste
13ª tappa Tour Cycliste

1999
1ª tappa Tour de l'Aude
3ª tappa Tour de l'Aude
Liberty Classic
13ª tappa International Challenge
2ª tappa Giro Donne
6ª tappa Giro Donne

5ª tappa Thüringen Rundfahrt
12ª tappa Grande Boucle
16ª tappa Grande Boucle
3ª tappa Holland Tour
4ª tappa Holland Tour
6ª tappa Holland Tour
Tour Beneden-Maas

2000
4ª tappa Redlands Bicycle Classic
1ª tappa Sea Otter Classic
3ª tappa Sea Otter Classic
Classifica generale Sea Otter Classic
1ª tappa Tour de l'Aude
4ª tappa Tour de l'Aude
7ª tappa International Challenge
5ª tappa Grande Boucle

2001
Campionati tedeschi, Prova in linea
2ª tappa Vuelta a Mallorca
4ª tappa Vuelta a Mallorca
2ª tappa Tour de l'Aude
5ª tappa Tour de l'Aude
Liberty Classic
6ª tappa International Challenge
4ª tappa Thüringen Rundfahrt
5ª tappa Thüringen Rundfahrt
5ª tappa Grand Prix du Québec
2ª tappa Holland Tour
4ª tappa Holland Tour
5ª tappa Holland Tour
Classifica generale Holland Tour

2002
Hamilton World Cup
Canberra World Cup
1ª tappa Gracia-Orlová
3ª tappa Gracia-Orlová
11ª tappa Tour de l'Aude
Liberty Classic
1ª tappa International Challenge
4ª tappa International Challenge
1ª tappa Grande Boucle
Rotterdam Tour
Classifica finale Coppa del mondo

2003
1ª tappa Gracia-Orlová
5ª tappa Gracia-Orlová
Prologo Tour de l'Aude
11ª tappa Grande Boucle
14ª tappa Grande Boucle

2004
3ª tappa Geelong Tour
3ª tappa Gracia-Orlová
2ª tappa Tour de Grand Montréal
Liberty Classic
2ª tappa GP Krásná Lípa
3ª tappa Thüringen Rundfahrt
4ª tappa Thüringen Rundfahrt
Rotterdam Tour
Rund um die Nürnberger Altstadt

Pista
1991
Campionato del mondo, inseguimento individuale
1992
Giochi olimpici, inseguimento individuale

Piazzamenti

Competizioni mondiali

Campionati del mondo su strada
Chambéry 1989 - In linea: 52ª
Duitama 1995 - In linea: 48ª
Duitama 1995 - Cronometro: 18ª
Valkenburg 1998 - In linea: 60ª

Campionati del mondo su pista
Lione 1989 - Inseguimento individuale: 2ª
Maebashi 1990 - Corsa a punti: 4ª
Stoccarda 1991 - Inseguimento individuale: vincitrice
Valencia 1992 - Corsa a punti: 4ª

Giochi olimpici
Seoul 1988 - In linea: ritirata
Barcelona 1992 - In linea: 28ª
Barcelona 1992 - Inseguimento individuale: vincitrice
Sidney 2000 - In linea: 30ª

Vita privata
Apertamente lesbica, nel 1996 ha convissuto a Leipzig con la sua compagna Judith Arndt, anch'ella ciclista professionista; nel 2005 le due sono state ambasciatrici dei Gay Games, ma in seguito la loro storia è naufragata.

Note

Altri progetti

Collegamenti esterni

Vincitori di medaglia d'oro olimpica per la Germania


text:
Morning Market Update: Record For The S&P
- 30 April 2013
Global markets rallied overnight amid solid US economic data and optimism central banks will maintain stimulus plans boosted sentiment.
European stocks rose, pushing the Stoxx Europe 600 Index toward its longest streak of monthly gains since 1997, as Italy formed a new government and as U.S. consumer spending unexpectedly increased in March.
In London the UK's FTSE 100 added 32 points (+0.5%) to settle at 6458, whilst the German DAX added 59 points (+0.8%) at 7874.
Stateside, the S&P 500 rose 0.7% to 1594, topping a record close of 1,593.37 reached on April 11. The Dow Jones increased 106 points (+0.7%), to 14,819.
The S&P 500 has climbed 1.6% in April and is poised for its sixth straight month of gains, the longest streak of advances since September 2009.
The bull market in U.S. equities has entered its fifth year as the S&P 500 surged 136% from a 12-year low in 2009, driven by better-than-estimated corporate earnings and three rounds of monetary stimulus from the Federal Reserve.
Gold futures rose on speculation that the Federal Reserve will maintain bond purchases to bolster the U.S. economy, while demand for coins and jewellery climbed.
Gold futures for June delivery gained 0.9% to settle at $1,467.40 an ounce on the Comex in New York. The price headed for the biggest monthly drop since December 2011 after entering a bear market on April 12.
Crude rose to the highest level in more than two weeks as the Standard & Poor's 500 Index approached a record on optimism that central banks will maintain economic stimulus to bolster growth. Oil for June delivery climbed $1.50 to $94.50 a barrel on the New York Mercantile Exchange, the highest settlement since April 10.
The US dollar fell against 14 of its 16 most-traded peers before the Federal Reserve opens a two-day meeting tomorrow amid bets it will maintain bond purchases under quantitative easing for the foreseeable future.
Today's session will bring us data in the form of Private Sector Credit, at 11:30am, AEST.