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D'Alfonso-Curran: A Perfectly Pleasing Pairing
Some things just make the perfect pairing. Like, a summer day and a fine breeze. Or a crisp, peachy, highly acidic Grenache Blanc and spicy Thai food. Similarly, winemakers Kris Curran and Bruno D'Alfonso of D'Alfonso-Curran wines are that complementary pairing.
The Recipe for D'Alfonso-Curran Success
It's in their winemaking philosophy. Curran believes a winemaker must be flexible enough to treat each wine individually, taking into consideration, things like its ripening time or the size of the lot.
D'Alfonso sees a need to be rational. He believes a winemaker must anticipate the potential fails in order to be prepared to deal with such an eventuality.
Individually those winemaking styles give their respective labels identity. Together, they represent a union of strengths, forming the D'Alfonso-Curran line of wines designed to pair with food. And the Santa Ynez Valley is the perfect place for a culinary adventure as they determine the foods that pair best with the wines they are working on.
Our Interview with Kris and Bruno
D'Alfonso and Curran joined us recently to discuss their winemaking, their backgrounds, and their individual and D'Alfonso-Curran labels. Learn more about what makes their winemaking styles unique in this month's video interview.
The History of these Two Established Winemakers
D'Alfonso, who's earned a reputation for producing outstanding Pinot Noirs, celebrated his 40th year as a winemaker last year. His career started at Chalone in the Edna Valley in 1980. A few years later he joined Richard Sanford at Sanford Winery. D'Alfonso became a partner at Sanford where he spent 25 years, before starting his own Badge and Di Bruno labels.
Curran, whose name is often cited as one of Wine Spectator's Top Winemakers, started her winemaking career as the assistant winemaker at Cambria Winery in Santa Maria right after college. From there she became a founding member of Koehler Winery. She went on to become the first winemaker at Sea Smoke and helped build that wine's cult status. After producing seven vintages at Sea Smoke, she accepted a winemaking position at Foley Wines where she made wines under the Foley, Lincourt, and Two Sisters brands. She built her Curran label in 1996 and was one of the first vintners in California to popularize Grenache Blanc, which she started making in 2003.
Together, the two renowned winemakers started the D'Alfonso-Curran brand in 2006 producing ultra-premium vineyard-designated Pinot Noirs from Sta. Rita Hills and Chardonnays from Santa Barbara County.
At the Los Olivos Wine Merchant & Cafe we focus on providing a true wine country experience. Much of our produce for the Café is organically grown at our Café farm in Los Olivos. And our award-winning wine selection of over 500 mostly local wines compliments our fresh wine country cuisine. As a hub for the local California Central Coast wine scene, we love getting to know our local winemakers and sharing their stories with you! We welcome you to browse our over 30 interviews and blogs featuring local winemakers HERE.
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The Visionary & the Winemaker behind Liquid Farm
Some ventures are fueled by inspiration, and others begin simply with the pursuit of passion. For Liquid Farm, it was a little of both.
Jeff Nelson and James Sparks of Liquid Farm began their venture with the desire to create Chardonnay in the Burgundian-style they enjoy so much. Prior to establishing Liquid Farm, the duo strived to eat and drink local, but they found something lacking with the local wines they were coming across in the early 2000s. Like many entrepreneurial-spirited individuals, they decided to take matters into their own hands and create wines that showcased some of the stellar cooler-climate vineyards in the Central Coast area while incorporating the Old World style that they both personally loved.
Liquid Farm began in 2009 and by 2010 they were available by the glass in Santa Ynez Valley restaurants like Los Olivos Wine Merchant & Cafe. The wine quickly found a following because of its earthy minerality and delicately nuanced style. In Old World tradition, the wines feature lower alcohol, high acidity, and more earth-driven characteristics. Fruit from the cool-climate and ancient soils of the Sta. Rita Hills complements this European winemaking style.
Working together Nelson and Sparks bring balance to Liquid Farm in many ways. As owner and CEO Nelson works on getting the wine to its audience, Sparks makes the wine. That balance also spills over into their winemaking philosophy.
Sparks said he likes to make wines that reflect his personality, delicate and layered with much to explore. It's a balance between science and artistry, with a little less emphasis on the science and more attention to craft and treating each barrel of wine individually.
We got to meet Jeff & James and now you can too!
Though they started Liquid Farm intent on making a stellar Old World Chardonnay, they shared a glass of their Pinot Noir with us at the Los Olivos Wine Merchant during their recent Featured Winemaker interview. In the video interview, they share how the evolution to include red wine in their production transpired, as well as how the label has found its niche in the Santa Ynez Valley.
Get to know James Spark's winemaking style this month at Los Olivos Café and Wine Merchant. Taste LIQUID FARM wines by the flight or purchase one of three featured bottles at a 20% discount throughout the month of January!
Stock up and Save Big! January Only!
At the Los Olivos Wine Merchant & Cafe we focus on providing a true wine country experience. Much of our produce for the Café is organically grown at our Café farm in Los Olivos. And our award-winning wine selection of over 500 mostly local wines compliments our fresh wine country cuisine. As a hub for the local California Central Coast wine scene, we love getting to know our local winemakers and sharing their stories with you! We welcome you to check out more of our interviews and blogs here.
Would you like to get to know more local winemakers and stay informed about our upcoming wine deals like our Final-Day-of-the-Month Blowout Wine? Sign up for our NEWSLETTER here.
From textbooks to tasting: Aaron Walker of Pali Wine Co.
If all had gone according to his plan, Aaron Walker would be steeped in academia shaping the minds of the next generation. Instead, those warm, magical SoCal breezes changed his fate. Now, he's influencing palates and educating wine aficionados about the virtues of California-style wines as winemaker for Pali Wine Co.
An easy-going Southern California native living the surfer lifestyle, Walker was planning on getting his teaching credential while studying at San Diego State University. Like many college students, Walker waited tables to pay the bills. It turns out the job suited him. He made several attempts at working in other industries, but he always went back to waiting tables.
A life-changing harvest
As fate would have it, his girlfriend (who is now his wife) steered him away from pursuing the culinary arts and opening a restaurant. She instead suggested that maybe her father's Central Coast contacts might have some opportunities for him in the wine industry.
Walker spent part of 2016 working the harvest with Jenne Bonaccorsi of Bonaccorsi Wine Co., and instantly forgot about teaching, forgot about restaurants, and forged a career in wine. The hands-on physical work followed by the reward of seeing that work come to fruition gave him a deep sense of satisfaction.
Embracing the California winemaking style
By 2017 he was hired by Pali Wine Co., which turned out to be a great fit. Short for Pacific Palisades, which sits between Malibu and Santa Monica, Pali was established in 2015 bearing reference to the hometown of owners Tim Perr and Scott Knight. At the time, Pali's winemaker was producing wines that didn't accurately reflect the California wine style. Originally, the wines were big, rich, high in alcohol, and didn't age well. Walker throttled that back a little bit, showcasing low-alcohol California wines that are big, yet approachable and can still age well. Pali especially favors Pinot Noir from Sta. Rita Hills, an area that has become renowned for its ideal growing conditions for the varietal because of its moderate warmth tempered by coastal influences.
We had the opportunity to sit down with Aaron to hear his story and would love to share it with you. We invite you to pour a glass of wine and join us as we uncover his tale in our interview at the Los Olivos Wine Merchant & Cafe.
Walker shared with us an example of that California style with the new release of the 2018 PCH. Pali produced 600 cases of this dry, crisp, and refreshing wine, which highlights flavors of watermelon, lime zest, and sweet summertime stone fruits.
The California influence is evident in the winery's operating philosophy as well. Pali has five tasting rooms throughout the Central Coast and Southern California, where staff has created a brewery approach to the tasting room experience. This has helped Pali foster loyal "communities of wine club members," and allows them to occasionally roll out experimental blends like the Zinfelder—a blend of Zinfandel and Dornfelder.
The Wines of Seagrape Wine Co. and their Maker: Karen Steinwachs
Curiosity guides the choices made in not only what wines she makes, but how she makes her wines. You may recognize her name, she's one of Santa Barbara's most prolific women in winemaking, Karen Steinwachs. Widely recognized as the talented winemaker behind the wines of Buttonwood, however, her private label wines of Seagrape Wine Co., express another side of Karen that will leave a stamp on the history of Santa Barbara County wine country.
Where did the name Seagrape come from?
Karen and her late husband were fond of their time spent abroad. While living in St. Croix they would marvel at the Seagrape trees on Grape Tree Beach. These grape trees, as the locals would call them, became the muse for their label, recalling a time of togetherness and fond memories from which their Seagrape wines were created. Karen is often asked if her wines are made with these sea grapes– they are not. They are made from grapes that grow beautifully from the Santa Barbara County's ocean influenced vineyards. Initially, the focus of Seagrape was on Sta. Rita Hills, with Chardonnay and Pinot Noir as the primary varietals she produced. Karen continues with that tradition but has expanded to welcome room for exploration and with that, we are excited to promote her first release of Gewurztraminer. (Surely not her last, you'll have to taste for yourself!)
Why Gewurztraminer?
This unique German grape may be intimidating to pronounce but in Karen's skilled hands she made it into a lovely approachable wine. This grape is not commonly seen in this area and can be made in many different ways similar to Reisling. One may expect this to be a sweet wine. However, Seagrape's 2017 Gewurztraminer is bone dry, with a nice balance of plushness and vibrancy with a zesty finish.
In our interview with Karen she shares what she enjoys about having her own label in addition to making wines for a bigger winery like Buttonwood– being able to explore a new varietal like Gewurztraminer is one of them.
We featured Karen's unique story on how she and her husband fled their lives in the fast-paced tech world for a quieter life in Santa Ynez Valley and henceforth Karen found her calling as a winemaker, in our 2018 interview and blog. Her story is one about creating one's own destiny, and her wines, whether Buttonwood or Seagrape, reflect her ability to go with the flow and know when to take the driver's seat. This balance is one that all winemakers grapple with but Karen makes look effortless.
Fried Chicken & Cremant? Norm from Flying Goat shares his pairing secrets
It's true – Norm swears on his Sparkling Crémant as an excellent pairing with fried chicken! (This 'secret' works with most sparkling, but when the winemaker himself tells you to pair Colonel Sanders and Flying Goat, you should listen!)
So what's the story behind the name Flying Goat?
While relaxing in his backyard sharing his newly bottled Central Coast Pinot Noir with friends and family, the question of what to name it kept coming up. As they sat with Pinot in hand, Norm's pygmy goats playfully flew through the air, it became apparent that they were calling out to get some kind of recognition– Flying Goat Cellars was born.
Norm's career began in the steps of his college roommate, who discovered a winemaking program from the University of California at Davis. While Norm graduated with an unrelated degree, he found winemaking as his muse to transform, as he put it, "from a beer-drinking football player into a winemaker."
Since UC Davis, Norm has left his signature on wines made from cool-climate vineyards, from Alexander & Napa valleys in Northern California, Willamette Valley in Oregon, to our local Central Coast. After being a highly recognized and respected winemaker for Foley and other wineries throughout his career, he now chooses to focus his energy on his own label which has always been about Pinot Noirs and Sparkling wines.
A tour of Central Coast Vineyards in a single Winery
In the spirit of his 38 years working the vines of cool climate vineyards, Flying Goat sources their grapes from the local sites with the longest ripening seasons, maximizing the quality of the crisp Pacific Ocean breeze. Flying Goat owns no vineyards, a specific style choice by Norm in the spirit of collaboration, trusting the esteemed producers he sources from to tend the soil and grapes that make their way to his bottles. Norm was one of the first winemakers to source Pinot Noir from the classic Santa Maria Valley AVA, Dierberg Vineyard almost two decades ago. Likewise, Flying Goat was one of the first "Rio Vista Vineyard" labeled wines back in 2003, and is the source of the famous 'Clone 2a' Pinot Noir, sourced from the far east lip of the Sta. Rita AVA.
Like so many of our local winemakers, Norm's intent in winemaking is to make food-friendly pairings. He loves the Goat Bubbles Crémant paired with chicken, key lime pie, or a savory brunch. Both the Clone 2a Pinot Noir and the Dierberg Pinot Noir are great with Beef, mushrooms, and root vegetables.
When Norm is not tending to making his wine, he can be found working at the Flying Goat & Goat Bubbles tasting room in Lompoc, a not-to-be-missed stop on the Lompoc Wine Ghetto tour.
Kat Gaffney – The New Face of Spear
From the heart & the hills of Sta. Rita
Spear makes full use of the unique coastal geography of the Sta. Rita Hills. In one of the states only east to west valleys, foggy, cool winds prolong the ripening season and define the cold-climate terroir of the valley. Over 60 vineyards dot the AVA, totaling nearly 3500 acres of planted grapes.
Spear vineyard sits on the southern face of the main valley, facing highway 246. As a hallmark Sta. Rita vineyard, the primary grapes they grow are Chardonnay and Pinot Noir. The vineyard is uniquely one of the highest elevation vineyards in the AVA, topping out at 900 feet above sea level. With a vineyard-forward approach to winemaking and a CCOF organic certification, Spear prides themselves on sustainable, eco-friendly wine farming. Spear wines are made in a gravity flow facility, gently flowing downhill. No oak flavoring, no new French oak. The vineyard was planted in 2013 with a winery and tasting room (appointment only, please!) Wines are meant to be a taste of the whole vineyard, essentially blends of different areas of the vineyards.
Kat Gaffney joined Spear after a world tour, that began in her native Colorado at a hotel wine bar. After a brief stint as a sommelier in training, Kat wanted to take a more active role in the winemaking industry and sought out apprenticeships and harvests to work, going from our Central Coast to Oregon's Willamette Valley, and out to New Zealand for practical winemaking experience in the flourishing Kiwi wine trade.
Humility in Winemaking
PC: Craft & Cluster
After heading back stateside, Kat worked at Spear under winemaker Greg Brewer, before taking over operations as head winemaker in 2017. Kat's winemaking style is about removing all intention in the winemaking. "I don't want people to taste the wine and say…' Kat your signature is all over this wine'… I want the vineyard to be front and center".
This month, we are featuring three Spear Wines from the high-elevation estate vineyard in the Sta. Rita Hills. The Estate Chardonnay is Spear's bread and butter (forgive the pun), sourced from blocks at varying elevations around the vineyard, north facing in sand and clay loam. Spear's Estate Pinot Noir is one of Kat Gaffney's first vine-to-bottle creations as winemaker, with blocks from the tip-top of the Spear estate to down near the 246, this all-estate/all-blocks Pinot was 15% whole cluster fermented. Rounding out our Featured Wines, the Spear Syrah is a Jeb Dunnuck 91-point rated estate creation featuring Alban clones and a white pepper and pomegranate nose.


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MSNBC Ridicules Romney for Collecting Food and Supplies for Sandy Victims
By Noel Sheppard | October 30, 2012 5:37 PM EDT
This one is really hard to believe, even for the most biased so-called "news network" in the nation.
MSNBC on Tuesday totally trashed Republican presidential nominee Mitt Romney for collecting food and supplies at a storm relief rally in Ohio to be sent to victims of Hurricane Sandy (video follows with transcript and commentary):
After introducing his Obama-supporting guests Atlanta Mayor Kasim Reed and Lehigh professor James Peterson, host Martin Bashir played a clip of the President speaking at the Red Cross headquarters in Washington Tuesday.
When the clip concluded, Bashir said, "Mayor Reed, so the Red Cross knows what it's doing. Did he, did you detect perhaps a subtle dig there on Mr. Romney who spent today going against the guidelines established by the Red Cross and holding a campaign rally in Ohio that was dressed up like a charity drive collecting food and other supplies when the Red Cross expressly asked people not to do that?"
Imagine that. A presidential candidate who gives millions of dollars a year to charity does a storm relief event in Ohio, and an MSNBC anchor is disgusted by it because the Red Cross would prefer people donating cash.
Yet according to the Washington Post:
The stop was billed as a "storm relief" event, and attendees were asked to bring non-perishable foods and other items for those affected by the storm. Long white tables to one side of the cavernous James S. Trent Arena were piled high with flashlights, batteries, diapers, toothbrushes, mini-deodorants, fleece blankets, cereal, toilet paper and canned goods.
Two large TV screens at the front of the venue bore the logo of the American Red Cross and the message: "Sandy: Support the Relief Effort. Text 'REDCROSS' to 90999 to make a $10 donation."
So besides the food and supplies that Ohioans generously donated, two large television screens asked participants to send money to the Red Cross.
But this didn't make Bashir happy. Ditto his Obama-supporting guests.
"I think that this is just another moment where you see the clear striking difference between a president who has a heart for the American people and someone who simply wants to be president of the United States," said Mayor Reed.
"Indeed," replied Bashir who then asked for Peterson's input.
"I would agree," echoed Peterson. "It's compassion that shows through in times like these. It's humanity that shows through in times like these, and it just seems clear that the President, in addition to stepping up and doing what he does as Commander-in-Chief, demonstrates compassion in these remarks and in his approach to this kind of serious disaster."
"All we've seen from Romney and from his surrogates is all kinds of politicizing and misdirection," Peterson continued, "and I think the American people in this sort of disastrous moment can really see in bold relief the differences between President Obama and former Governor Romney."
So having a storm relief event with tables "piled high with flashlights, batteries, diapers, toothbrushes, mini-deodorants, fleece blankets, cereal, toilet paper and canned goods" along with two large television screens calling for donations to the Red Cross demonstrates a lack of compassion on MSNBC.
Yet the network didn't end there.
About a half hour later, Bashir brought GQ's Ana Marie Cox on to trash Romney's event.
"I found that sort of fake, relief rally, whatever it is, to be pretty offensive, and also wrong-headed," said Cox. She actually called Romney "craven" for doing it.
I'm not kidding.
This was followed by MSNBC contributor Karen Finney saying, "As a former governor, I would think that he would know that what the Red Cross needs in times like this is money and blood."
Yes, that's why there were two large television screens asking for people to donate to the Red Cross.
I guess the geniuses at MSNBC so blinded by their desire to get Obama re-elected didn't notice that, nor did they recognize that they were spitting on all the people in Ohio that turned out for this event to give of themselves to their fellow Americans in need.
Shame on Bashir and all those involved in this despicable couple of segments.
National tragedies like this are when we're all supposed to come together as a nation.
It's apparent that's not possible for these shills.
*****Update: Karen Finney has asked that I supply the fuller transcript of her discussion with Bashir on this subject:
ANA MARIE COX: I found that sort of fake relief rally, whatever it is, to be pretty offensive and also wrong-headed. You know, the Red Cross is put in this awkward position of saying, you know, "We don't need canned goods, thank you very much, Mr. 1950s. You know, like we need money, we need people to donate blood." And I think that sort of is Mitt Romney sort of writ small as it were, right? Like to not only do something so craven, but to do it in a way that's not even helpful on a small scale.
MARTIN BASHIR: So Ana Marie, was it purely a photo opportunity? Was it purely for the sake of having people walk past him, hand him cans, and be on television?
COX: Well, it almost has to be seeing as how the thing he was doing was not something that the Red Cross actually needed. And so it almost has to be purely for politics purely as a photo-op. I mean, that's his entire campaign, purely a photo-op really.
BASHIR: Karen, you wanted to add something to that.
KAREN FINNEY: Well, I was just going to say, you know, Martin, the thing is like when you have a platform or an opportunity to communicate a message particularly in a time like this, I think it's incumbent on you to make sure that you're communicating what is the most effective, helpful thing. And as a former governor, I would think that he would know that what the Red Cross needs in times like this is money and blood. Of course, it is human nature to want to help your fellow American that's in trouble and to think "Oh, I'll buy food or I'll buy clothes." But again, as we've been doing here on MSNBC and I hope other networks are doing, sort of helping, being a part of helping direct people to websites where they can donate or find out exactly what's needed. I mean, that really should be the role. If they wanted to do something helpful, that would actually be the thing they could have been doing that would be helpful.
Please recall what the Post reported concerning this matter: "Two large TV screens at the front of the venue bore the logo of the American Red Cross and the message: 'Sandy: Support the Relief Effort. Text 'REDCROSS' to 90999 to make a $10 donation.'"
As such, Romney did exactly what Finney et al claimed he should have, but they still ridiculed him for it.
Beyond this, the Red Cross website has a section called "Smart Giving Tips for Disasters." It does indeed address giving cash first, but doesn't prohibit other kinds of donations.
There a lot of ways to help in this situation, and if people were giving food, clothes, or supplies that they had taken from their homes to help in this situation - maybe because that's all they have! - mocking it is disgraceful.
*****Update II: It turns out MSNBC's Andrea Mitchell ridiculed Romney's storm relief rally hours before Bashir. Insanity surely runs rampant at this network.
2012 Presidential MSNBC Martin Bashir Video Karen Finney Ana Marie Cox Martin Bashir Barack Obama Mitt Romney

redpajama_set_name: RedPajamaCommonCrawl


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It's great to see Woody Allen back in a familiar acting role. No, he isn't the Fading Gigolo of the title (that refers to actor, writer, and director John Turturro), but he enjoys the best scenes and lines in this mildly amusing sex comedy. Unfortunately, the overall film feels under-cooked and unsatisfying. The script is sometimes puzzlingly crass and much of the dialogue sounds corny. If not quite a turkey, Fading Gigolo is a bit of a lame duck.
During the opening credits the camera roams the storefronts of Brooklyn, New York in sepia Super 8 nostalgia mode. Murray Schwartz (Woody Allen) announces in voiceover that his bookshop, owned by his grandfather and father before him, is being forced to close. It is the 'end of an era'.
But we have no time to ponder this, as, with an abrupt grinding of gears, Murray tells his good friend Fioravante (John Turturro) that his dermatologist, Dr. Parker (Sharon Stone) is interested in having a menage-a-trois. She asked him whether he knew anybody and he said 'yes, but it will cost you a thousand bucks.' Murray tells Fioravante, 'I was thinking of you.' 'Are you on drugs?' replies his friend. 'Apart from my Zoloft, no,' comes the answer.
Murray sets himself up as a 'pimp' to his friend's 'ho' (60/40 split). 'Hey, it's the world's oldest profession,' is supposed to justify this 'business' idea. If this was, say, Eddie Murphy and Zac Efron in a Farrelly Brothers gross-out, then it might make sense. But Woody Allen and John Turturro? Really?
So the dapper, soulful florist, Fioravante, becomes a big success with his lady clients and the dubious partnership, now calling itself Virgil and Bongo, rakes in the money. Until the gigolo falls in love with lonely orthodox Jewish widow, Avigal (Vanessa Paradis) and Murray gets into trouble with the local Hasidic Safety Patrol for wandering too far from his tribe.
For Woody Allen fans, it's a pleasure to see him acting back home in New York once again. Fading Gigolo is no Manhattan or Annie Hall, but there is one diamond scene of old school slapstick that has us yearning for more. His funny lines, as when he's trying to convince Fioravante that gigolos don't need to be drop-dead handsome – 'is Mick Jagger good looking? He opens his mouth and it's horrible' – only make the rest seem dull. Perhaps these were ones that he improvised himself.
As a character actor, John Turturro is an indie hero. He has played several memorable roles in Coen brothers and Spike Lee films: who can forget his Jesus, the bowling kingpin in The Big Lebowski? Here, he gives us glimpses of witty filmmaking – the jump cut from an orgasm to a fat man hosing the streets; the shot through the legs of Sofia Vergara which looks like a homage to The. Graduate. But Fading Gigolo doesn't really hang together. For a comedy, there aren't enough laughs. Fans of romance will find its ending unsatisfying. And for viewers wanting threesomes with Sharon Stone and Sofia Vergara, there's scant hot action.
Is Turturro trying to say something serious about relationships? His characters don't properly come alive or have any psychological depth. To justify her sexual adventures, Dr. Parker says 'everybody has all sorts of people inside of us, bursting to get out'. Then, at the end, the Hasidic Safety Patrol guy, who has been in love with Avigal all along, says, 'it's hard for a man to understand a woman's feelings.'
That's about as profound as it gets.


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Author: Staff
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We'll provide food for the South-West – Aregbesola
Osun State Governor, Rauf Aregbesola, yesterday said the state will provide food for the South-West states and capture a sizable chunk of the N3 billion daily food market in Lagos State.
The governor said with more than 60 tourism sites in the state, his government is poised to provide food for the South-West states. Governor Aregbesola said this while delivering his address at a Trade, Investment and Culture Conference at the Centre for Black Culture and International Understanding in Osogbo.
He said in his two and a half years in office, his administration has done its best to promote the tradition and culture of the Yoruba.
"Our goal therefore is to provide food for the South-West and capture a sizable chunk of the N3 billion daily food market in Lagos. By a stroke of fortune, our natural endowment also includes solid minerals, especially gold. "In our development drive, we have focused mainly on four key areas.
These are culture and tourism, agriculture, information technology and solid minerals. We assure you that the South-West states will rely on us for their needs very soon.
"Osun is indisputably the custodian of the cultural heritage of the Yoruba people, who are mainly domiciled in and originated from the South-West of the country.
"Ile-Ife, which is in this state and just about 30 minutes drive from this podium, is the cradle of Yoruba culture and civilization," the governor told investors and others in the gathering.
He also added that Osun occupies a central place in Nigeria's cultural tourism map, stressing that besides Ife, there are numerous other centres of cultural and tourism significance across the state.
"We have gold deposits in commercial quantity in many parts of the state that are waiting to be fully exploited. It is our goal to develop this in partnership with willing and capable partners," the governor said.
He added that his administration will ensure that the interactive platform will be a continuous one to demonstrate the seriousness of its commitment to the path it has chosen.
NATIONAL MIRROR
Staff August 21, 2013 0
UPDATE: Applauds as Aregbesola meets grass root people
Following the interactive public feedback session titled 'Gbangba D'ekun' by the Governor, Ogbeni Rauf Aregbesola, there have been reactions from people of the state.
The programme which witnessed hundreds of people across Iwo local government had students, teachers, artisans, traders and civil servants in attendance.
Mr. Abdulateef Olaitan Arewa, a civil servant said, "the programme is another beautiful idea to meet the real "grassroot" people in the State" adding that it is devoid of partisan politics; he also noted that "I will prefer if this kind of interesting programme can be on weekends so as to carry the elites along to further sensitize those who speak ill of the administration of Ogbeni Aregbesola."
Alabi Caleb Olatunji Aregbe in his opinion described the present State Government as the most vibrant and administratively clairvoyant Governor in the whole of the nation. "I stand to be corrected, the facts are there for everyone to see", he added.
Similarly, a health official in the state, Mr. Taoheed Ademola OmoOmi said the initiative by the government to meet those at the grass root is a clear indication as to why the people of the state adore the governor. "For a Governor that makes himself available to his people at anytime, truly Ogbeni Rauf Aregbesola is the man of the people", he added.
Well done Ogbeni!
BREAKING NEWS: Osun Declares Public Holiday for traditionalists…
Government of the State of Osun has declared today (Tuesday August 20, 2013) as a public holiday in celebration of world traditional religion Isese Day.
This was contained in a press statement signed by the State Commissioner for Information and Strategy, Mr Sunday Akere.
According to the commissioner, Governor Rauf Aregbesola declared the public holiday in the spirit of equality among the various religious groups in the state.
Isese day, among the traditional believers, is the celebration of the peak of festivity in Yorubaland tagged Odun Nla, hence were given the right to celebrate with members of their family.
(culled from OSUN DEFENDER)
GBANGBA DEKUN: Aregbesola goes to grassroots…
The Government of the state of Osun under the leadership of Ogbeni Rauf Aregbesola will continue to make itself relevant to the people in deeds and in words.
State commissioner for Information and Strategy, Honourable Sunday Akere stated this, as he disclosed that a new programme to ensure this has been inaugurated. The programme is tagged GBAGBA DEKUN.
Mr. Sunday Akere , who disclosed that the Aregbesola government is in romance with the people as it has ensured that they are carried along in all its policies and projects, said the programme would afford the government the opportunity of feedback that will propel government in the right direction.
According to the commissioner, Gbangba Dekun will be a direct participation programme where the people will meet the governor at the town hall of a chosen venue.
The people will have the opportunity to express their views and opinions, as well as offer advice on all government policies, programmes and projects relevant to their communities.
Mr Akere added that the maiden edition of the programme will take place in Iwo Federal Constituency at Iwo town hall today Tuesday, August 20, 2013 at 9am.
He then urged community leaders, traditional rulers, market men and women, youth organizations and other stakeholders in the federal constituency to attend the programme so as to bare their mind to Mr Governor.
The programme would be aired live on both the state radio and television stations and all the federal constituencies in the state would play host to it, as it is designed purely as an avenue to inform Mr governor of their feelings about governance in their communities so far.
Osun to immortalise Susanne Wenger, others…
OSUN State government has concluded arrangements to immortalise late German cultural icon, Mrs. Susanne Wenger and others who have contributed significantly to the development of arts and culture in the state.
The state government said it will put in place a hall of fame to immortalise both living and dead cultural icons for their various contributions to cultural development in the state.
Chairman, Osun State Tourism Board, Mr. Abimbola Daniyan at a press conference in Osogbo yesterday also explained why the state government has committed huge sum of money to tourism development in the state.
Special Adviser to Governor Rauf Aregbesola on Culture and Tourism, Mr. Oladipo Soyode stated that artistes who are traceable to the state would be included in the state's hall of fame.
He said though Susanne Wenger who died about four years ago has not had any monument named after her, the state government has always been celebrating her during the annual Osun Osogbo festival.
Photos – Committee on review of scheme of civil service in Nigeria meets Aregbesola
Committee Head of Service-1 From right Governor State of Osun, Ogbeni Rauf Aregbesola; Head of Service,Niger State, Mr. Ibraheem Yakubu and his Kano State counterpart, Alhaji Umar Jalo, during the visit of Committee of the Review of earlier Reports on the Scheme of States Civil Service; Federal; Local Government;Judicial Employee and 1999 Constitution to the Governor in his office, Osogbo, State of Osun on Monday 19-08-2013
Committe Head of Service-2 Governor State of Osun, Ogbeni Rauf Aregbesola; Head of Service, Adamawa State, Alhaji Musa Kaibo and Deputy Governor, Mrs Titi Laoye-Tomori, during the visit of Committee of the Review of earlier Reports on the Scheme of States Civil Service; Federal; Local Government; Judicial Employee and 1999 Constitution to the Governor in his office, Osogbo, State of Osun on Monday 19-08-2013
Committee Head of Service-3 Governor State of Osun, Ogbeni Rauf Aregbesola; Head of Service State of Osun, Mr Sunday Owoeye and Mr Francis Bajowa, representing Federation Head of Service, during the visit of Committee of the Review of earlier Reports on the Scheme of States Civil Service; Federal; Local Government; Judicial Employee and 1999 Constitution to the Governor in his office, Osogbo, State of Osun on Monday 19-08-2013
Committee Head of Service-4 Governor State of Osun, Ogbeni Rauf Aregbesola; Abuja Head of Service, Mr Rotimi Anifowose; Mr David Olagbenro, from office of the Head of Service and Imo State Head of Service, Mrs Agustina Opara, during the visit of Committee of the Review of earlier Reports on the Scheme of States Civil Service; Federal; Local Government; Judicial Employee and 1999 Constitution to the Governor in his office, Osogbo, State of Osun on Monday 19-08-2013
Osun Government promises loans to artisans, traders…
Osun State Government has announced plans to offer soft loans to artisans and traders to enable them succeed in their vocation as this empowers them to contribute their quota to the state economy.
Governor Rauf Aregbesola who disclosed this during the formal inauguration of the state chapter of the Federation of Informal Workers' Organisation of Nigeria (FIWON), in Osogbo said that if artisans and traders who form informal workers are assisted by government to succeed, the economy would be more stable and the entire country would be better for it.
The governor regretted that in spite of the importance of the artisans and traders to the economy of a state and country at large, many governments, especially at the center still do not recognise their role in the development of the economy.
He said: "The success informal workers make in your businesses will determine the level of development in our economy. Because government don't pay attention to your role in the economy, that is why our economy has not developed more than this and that is why there is poverty everywhere."
"Our government is saying that we can't do it all once, but gradually, we will continue to introduce programmes that will take off poverty among our people."
Workers at the Ministry of Information receive commendation for cleanliness
All the staff of the Ministry of Information and Strategy have been commended for their untiring efforts in ensuring that the Ministry is always kept clean through the weekly environmental exercise. The Permanent Secretary in the Ministry, Engr. Segun Aduroja gave this commendation while monitoring the weekly environmental exercise carried out by the staff of the Ministry. Engr. Aduroja said since cleanliness is next to Godliness, one does not need anybody to prompt him or her before making sure that, one lives in a healthy environment.
The Permanent Secretary who specifically commended the manner in which the staff responded to the cutting of weeds in all the surroundings urged them not to be deterred but should rather strive to maintain the tempo. He said the present government has since inception inculcated in the inhabitants of the state the culture of living in a good and clean environment.
The onus therefore, is on the people to imbibe the habit. He stressed further that several millions of naira had been spent to clear canals, waterways and drainages in every part of the state, all in an effort to enable the people live happily without entertaining the fear of flooding which many states have experienced recently.
(Culled from- http://www.onewsportal.com)
Osun Government parleys with MDS Market Association
The Governor of the State of Osun, Ogbeni Rauf Aregbesola has assured the displaced MDS Market Association in Osogbo that, there is availability of thirteen (13) hectares of land at their advantage which will be monitored for an organized development.
The Governor who was represented by the Commissioner for Lands, Physical Planning and Urban Development, Arc. Muyiwa Ige admonished the affected traders to stop displaying wares under canopies and umbrella along the corridors of the road because of the safety of their lives.
Arc. Ige assured the traders that their request of palliative will be tabled before the Governor for consideration. He also urged the traders to relocate speedily to either of the two available International Markets in the state capital.
(culled from www.onewsportal.com)


For ShoutMeLoud, I use Facebook as a Significant social Media channel to connect with different Shouters. To assist me with this process, I apps and utilize Facebook tools.
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Tunji-Olayeni, P .F and Mosaku, T. O. and Amusan, L. M. and Omuh, I. O. (2013) A comparative study of the Entrepreneurial Characteristics of Architecture and Building Students: Evidences from a Developing Economy. In: Creating Global Competitive Economies, November 13-14 2013, Rome, Italy.


WATERING YOUR GARDEN… for most Salespeople their most valuable asset is their Database… you know, your list of Past Clients and Centers of Influence. For obvious reasons it is your "most valuable asset" because of the Trust Factor. They know you and trust you and as a result they will either do business with you again or send you referrals. It is the easiest business to secure by far. Ironically this list does not always get the attention it deserves! Sometimes Salespeople forget to "water their garden" and the crops start to die.
Stage #1. You don't call them often enough to keep in touch.
Stage #2. When you finally do call them, the conversation takes too long because there is so much "catching up" to do.
Stage #3. Because Stage #2 becomes tedious, you avoid calling them again.
Stage #4. Because the Database doesn't hear from you, you are not "top of mind". The next time they need your services they go elsewhere and do the same with their referrals.
Stage #5. Your Database dies off and your "most valuable asset" shrinks rapidly. Your crops are dying!
Here is your ACTION STEP… in order to protect your "most valuable asset" it is critical to make sure you are "watering your garden" on an ongoing basis.
Stage #1. You establish a "frequency of contact" minimum standard for your Database (eg: a phone call every 90 days and a mailing piece/e-mail every 90 days). Whatever frequency you decide just remember to be consistent.
Stage #2. The conversations don't take long because the "catching up" time is much shorter.
Stage #3. Your contact is meaningful and productive… Asking for Referrals becomes a natural part of the relationship.
Stage #4. Business regularly flows your way because when you consistently "water your garden", the results are pleasantly predictable.
Stage #5. BONUS: Your Database continues to grow. Why?… The results you are generating encourage you to add more names on an ongoing basis. It's working!
So the choice is yours… look after your "most valuable asset" on a regular basis and your business will thrive (if you don't, someone else will be harvesting from your garden!). Start by looking at your existing Database, set up a regular follow-up system that outlines your "frequency of contact" and put it in your calendar. Remember the two keys… frequency and consistency. NO Excuses.


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With the current fragmentation of early childhood programs, it is not uncommon for one child to move from child care, to school programs or Head Start, to specialized services, and back to child care all in one day. Transportation, dealing with various providers and different system expectations can have has a detrimental impact on children and their families. More and more communities and their early childhood programs are bringing the different programs into one building and children into the same classrooms.
What is an Early Learning Center?
10 Points that Distinguish an ELC from a Primary Grade School.
Governance: Locus of control with staff and parents, i.e., charter status. Government units have oversight on the "intent" of all funding streams.
Collaboration: At least four programs/funding streams should be included: Regular education, special education, Head Start and child care. Under the ELC roof, the programs are functionally blended. Space also available for health/social service providers as well as family/community functions.
Hours of the Center: Would be open a minimum of 2,000. Operation: hours/year (9 hours a day, 45 weeks a year).
Family-Centered: Consumer friendly, designed to meet parent "where they are at." Most important question, "What do you want your child to be like when they grow up?"
Staffing: Team teaching, career ladder, continuous improvement, Patterns: adult child ratio low. Teacher child ratio may be high.
Facilities: Designed expressly for young children, staffing patterns and parents.
Funding: Business manager handles funding streams. Under the roof are endless variations on one program.
Accountability: Results based. (How did the kids turn out at age 25?) The ongoing question, "How do we know we're getting there?" Shared responsibility, TQM, portfolios.
Curriculum Choices: Responsive to child's learning style and respectful of parents values. Developmentally appropriate practices.
Over the next ten years, thousands of schools will need to be built, and even more will need to be renovated in order to respond to rising enrollments and to repair aging schools. New and renovated schools will need to last for many years and will leave a lasting legacy throughout the 21st century. It is crucial that parents, teachers, and a broad range of community members are actively involved in the planning and design of the new schools and renovation projects, so that schools of the 21st century are truly centers of community.


Such an amazing soup. I used 4 potatoes, and 1 big white onion. put them in the boiling water until the potatoes were really soft, then pureed them, put them back in the pot, and added the sauteed leeks. just amazing.
Heat the oil, butter and a pinch of salt in a large pot over medium heat. Add the leeks & onion, sauté until softened, about 5-6 minutes.
Add the potatoes, garlic, thyme, rosemary, and coriander. Sauté for 2-3 minutes.
Add the vegetable broth, bay leaf, salt, and pepper. Raise heat so it starts to simmer. Now reduce heat to a low simmer and cook for about 15-20 minutes, or until the potatoes are fork tender.
Remove from heat and remove bay leaves. Stir in the coconut milk and optional lemon juice. Taste for seasoning and add more to taste.
Using an immersion blender, blend until smooth and creamy. You can also use a regular blender and carefully blend in batches. Before blending, set aside a few pieces of potato for the garnish.
Serve in soup bowls and top with chopped green onion, fresh ground pepper and a few pieces of cooked potato.


text:
Алекса́ндр Леони́дович Ги́нцбург (род. 10 ноября 1951, Москва) — советский и российский , директор НИЦЭМ им. Н. Ф. Гамалеи (с 1997 года), академик РАН (2013; с 2004 — академик РАМН). Лауреат Государственной премии Российской Федерации в области науки и технологий (2020).

Биография
Родился 10 ноября 1951 года.

В 1974 году окончил биологический факультет МГУ (на момент поступления — биолого-почвенный факультет).

После окончания университета в течение 7 лет работал в биологическом отделе Института атомной энергии им. Курчатова (Москва) под руководством молекулярного генетика Р. Б. Хесина-Лурье.

В 1981 году во ВНИИ генетики и селекции промышленных микроорганизмов защитил диссертацию на соискание учёной степени кандидата биологических наук по теме «Влияние мутаций Escherichia coli, изменяющих фактор терминации транскрипции, на развитие четных Т-фагов».

С 1982 года по настоящее время работает в Научно-исследовательском институте эпидемиологии и микробиологии АМН СССР (ныне НИЦЭМ им. Н. Ф. Гамалеи).

В 1989 году в НИЦЭМ защитил диссертацию на соискание учёной степени доктора биологических наук по теме «Формирование, распространение и экспрессия детерминант патогенности Vibrio cholerae и jersinia Pseudotuberculosis — процессы, определяемые мигрирующими генетическими элементами».

С 1997 года — директор НИЦЭМ.

С 2000 года — заведующий кафедрой инфектологии медико-профилактического факультета послевузовского профессионального образования Московской медицинской академии имени И. М. Сеченова.

В 2000 году избран членом-корреспондентом, а в 2004 году — академиком РАМН. В 2013 году стал академиком Российской академии наук (в рамках присоединения РАМН к РАН).

Семья
 Отец, Леонид Леонидович Гинцбург (4.12.1925 — 14.07.2018) — доктор технических наук, профессор, заведующий лабораторией НАМИ, заслуженный деятель науки и техники РФ.

Научная деятельность
Специалист в области молекулярной биологии патогенных микроорганизмов.

Выдвинул и обосновал положение о том, что гены факторов патогенности входят в состав мобильных генетических элементов.

Сформулировал концепцию, согласно которой одним из механизмов, позволяющих возбудителям сапронозов формировать эндемичные природные очаги, является способность патогенных бактерий сохранять жизнеспособность в объектах внешней среды в межэпидемические периоды в некультивируемом состоянии.

Член редколлегий ведущих российских журналов по медицинской микробиологии: ЖМЭИ и «Молекулярная генетика, микробиология и вирусология».

Член президиума Всероссийского общества микробиологов и эпидемиологов имени И. И. Мечникова.

Награды
 Орден Александра Невского (8 ноября 2021 года) — за заслуги в области здравоохранения и многолетнюю добросовестную работу.
 Орден Дружбы (29 апреля 2019 года) — за большой вклад в развитие здравоохранения и многолетнюю добросовестную работу.
 Премия Правительства Российской Федерации (в составе группы, за 2003 год) — за разработку технологии, организацию промышленного выпуска и внедрение в медицинскую практику готовых лекарственных форм нового отечественного препарата «Циклоферон».
 Государственная премия Российской Федерации в области науки и технологий за 2020 год, за разработку и внедрение в практику отечественного здравоохранения эффективных рекомбинантных вакцин против лихорадки Эбола и новой коронавирусной инфекции (COVID-19), а также за разработку технологии конструирования вирусных систем доставки кассет со вставкой гена гликопротеина вируса Эбола и гена S-белка SARS-CoV-2.
 Знак Российского еврейского конгресса Global Influence Award (2021).
 Премия Федерации еврейских общин России в номинации «Наука» (2021) — «за выдающийся вклад в развитие отечественной эпидемиологии».

Основные работы

Примечания

Ссылки

Выпускники биологического факультета МГУ
Преподаватели 1-го МГМУ
Лауреаты Государственной премии РФ в области науки и технологий

redpajama_set_name: RedPajamaWikipedia


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Maintains healthy nerves and myelin, helping to maintain normal brain function. DHA is a key component of the phospholipid membranes contained in the retina and hence supplementation may help maintain eye health.
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text:
Victoria James
Associate Professor in Cancer Biology and Gene Expression, Faculty of Medicine & Health Sciences
PhD and Job Opportunities
workSchool of Veterinary Medicine and Science
Sutton Bonington Campus
Sutton Bonington
LE12 5RD
work0115 951 6797
Victoria.James@nottingham.ac.uk
Victoria obtained a PhD in genetics from the University of Leicester in 2007. Following her PhD studies, she pursued postdoctoral training in the fields of molecular and cell biology. Victoria was awarded the prestigious JG Graves Research Fellowship in 2012, which she held at the University of Sheffield Cancer Research Centre until joining the University of Nottingham as a lecturer in 2014. Victoria now splits her time between research and teaching and is an active member of the University of Nottingham's Cancer Research Priority Area.
Teaching Summary
Victoria is involved in teaching on a range of undergraduate and postgraduate courses offered by the University of Nottingham. Victoria's teaching philosophy centres on student interaction and… read more
Victoria's research is focussed on understanding the complex mechanisms that lead to cancer progression and metastasis. Her group investigates how extracellular communication, via RNA and proteins,… read more
PROBERT C, DOTTORINI T, SPEAKMAN A, HUNT S, NAFEE T, FAZELI A, WOOD S, BROWN JE and JAMES V, 2018. Communication of prostate cancer cells with bone cells via extracellular vesicle RNA; a potential mechanism of metastasis. Oncogene. 38(10), 1751-1763
ES-HAGHI, MASOUMEH, GODAKUMARA, KASUN, HALING, ANNIKA, LATTEKIVI, FREDDY, LAVRITS, ARINA, VIIL, JANELI, ANDRONOWSKA, ANETA, NAFEE, TAMER, JAMES, VICTORIA, JAAKMA, ULLE, SALUMETS, ANDRES and FAZELI, ALIREZA, 2019. Specific trophoblast transcripts transferred by extracellular vesicles affect gene expression in endometrial epithelial cells and may have a role in embryo-maternal crosstalk. Cell communication and signaling : CCS. 17(1), 146
KLETUKHINA, SEVINDZH, NEUSTROEVA, OLGA, JAMES, VICTORIA, RIZVANOV, ALBERT and GOMZIKOVA, MARINA, 2019. Role of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Epithelial-Mesenchymal Transition. International journal of molecular sciences. 20(19),
CHULPANOVA DS, SOLOVYEVA VV, JAMES V, ARKHIPOVA SS, GOMZIKOVA MO, GARANINA EE, AKHMETZYANOVA ER, TAZETDINOVA LG, KHAIBOULLINA SF and RIZVANOV AA, 2020. Human Mesenchymal Stem Cells Overexpressing Interleukin 2 Can Suppress Proliferation of Neuroblastoma Cells in Co-Culture and Activate Mononuclear Cells In Vitro. Bioengineering (Basel, Switzerland). 7(2),
Applications for PhD positions are invited all year round from exceptional graduates to study the contribution of extra-cellular communication and non-coding RNAs to cancer progression and metastasis.
Funding Notes:
Candidates interested in joining the lab to work in this research area can contact Dr James by sending an e-mail to victoria.james@nottingham.ac.uk. Currently positions are only available to self-funded students. There are a number of international studentships available to international applicants: see http://www.nottingham.ac.uk/InternationalOffice/prospective-students/scholarships/index.aspx.
Victoria is involved in teaching on a range of undergraduate and postgraduate courses offered by the University of Nottingham. Victoria's teaching philosophy centres on student interaction and engagement, implemented through the integration of technology and traditional teaching strategies.
Victoria's research is focussed on understanding the complex mechanisms that lead to cancer progression and metastasis. Her group investigates how extracellular communication, via RNA and proteins, promotes cancer progression and the adaption of the metastatic niche, with the aim of identifying novel markers to better stage and predict disease behaviour for the development of novel therapeutic strategies. Victoria has a specific interest in both primary and metastatic cancers of bone as well as cutaneous and other soft tissue tumours.
CHULPANOVA DS, GILAZIEVA ZE, KLETUKHINA SK, AIMALETDINOV AM, GARANINA EE, JAMES V and RIZVANOV AA, 2021. Cytochalasin B-Induced Membrane Vesicles from Human Mesenchymal Stem Cells Overexpressing IL2 Are Able to Stimulate CD8+ T-Killers to Kill Human Triple Negative Breast Cancer Cells Biology. 10(2), 141
GOMZIKOVA, M, JAMES, V and RIZVANOV, A, 2021. Mitochondria donation: current understanding and mitochondria transplantation strategies Frontiers in Cell and Developmental Biology. 9,
OGURCOV, S, SHULMAN, L, GARANINA, E, BAICHURINA, I, KUZNETCOV, M, MASGUTOVA, G, KOSTENNIKOV, A, RIZVANOV, A, JAMES, V and MUKHAMEDSHINA, Y, 2021. lood serum cytokine levels in patients with subacute spinal cord injury: a pilot study to search for biomarkers of injury severity and level Brain Science. 11(3),
KLETUKHINA, SK, NEUSTROEVA, OA, KURBANGALEAVA, SV, SALAFUTDINOV, II, ROGOV, AM, JAMES V, RIZVANOV, AA and GOMZIKOVA, MO, 2021. Storage stability and delivery potential of cytochalasin B induced membrane vesicles Biotechnology Reports. 30, e00616
THOMAS J BROWN, 2021. The Role of Extracellular Vesicles in the Development of a Cancer Stem Cell Microenvironment Niche and Potential Therapeutic Targets Cancers. 13(10), 2435
KITAEVA KV, PRUDNIKOV TS, GOMZIKOVA MO, KLETUKHINA SK, JAMES V and RIZANOV AA, 2019. Analysis of the interaction and proliferative activity of adenocarcinoma, peripheral blood mononuclear and mesenchymal stromal cells after co-cultivation in vitro BioNanoScience. 9, 502-509
GOMZIKOVA MO, JAMES V and RIZVANOV AA, 2019. Therapeutic Application of Mesenchymal Stem Cells Derived Extracellular Vesicles for Immunomodulation. Frontiers in immunology. 10, 2663
MUKHAMEDSHINA Y, SHULMAN I, OGURCOV S, KOSTENNIKOV A, ZAKIROVA E, AKHMETZYANOVA E, ROGOZHIN A, MASGUTOVA G, JAMES V, MASGUTOV R, LAVROV I and RIZVANOV A, 2019. Mesenchymal Stem Cell Therapy for Spinal Cord Contusion: A Comparative Study on Small and Large Animal Models. Biomolecules. 9(12),
SHAIMARDANOVA AA, SOLOVYEVA VV, CHULPANOVA DS, JAMES V, KITAEVA KV and RIZVANOV AA, 2019. Extracellular vesicles in the diagnosis and treatment of central nervous system diseases. Neural regeneration research. 15(4), 586-596
GALIEVA LR, JAMES V, MUKHAMEDSHINA YO and RIZVANOV AA, 2019. Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders. Frontiers in neuroscience. 13, 163
CHULPANOVA, D.S., KITAEVA K.V., TAZETDINOVA L.G., JAMES V., RIZANOVA A.A. and SOLOVYEVA V.V., 2018. Application of Mesenchymal Stem Cells for Therapeutic Agent Delivery in Anti-tumor Treatment Frontiers in Pharmacology. 9, 259
CHULPANOVA D.S, KITAEVA K.V, JAMES V, RIZANOV A.A and SOLOVYEVA V.V, 2018. Therapeutic Prospects of Extracellular Vesicles in Cancer Treatment Therapeutic Prospects of Extracellular Vesicles in Cancer Treatment. 9, 1534
CATRIN S RUTLAND, SIMONE DE BROT, VICTORIA JAMES and NIGEL P MONGAN, 2017. Expression Mediated by Noncoding RNA in Cancer. In: JAYPROKAS CHAKRABARTI and SANGA MITRA, eds., Cancer and Noncoding RNAs 1. 1. Academic Press Elsevier. 359-366
SIMONE DE BROT, CATRIN S RUTLAND, NIGEL P MONGAN and VICTORIA JAMES, 2017. Epigenetic control of microRNA expression and cancer. In: JAYPROKAS CHAKRABARTI and SANGA MITRA, eds., Cancer and Noncoding RNAs 1. 1. Academic Press Elsevier. 373-378
MAJCHER V, GOODE A, JAMES V and LAYFIELD R, 2015. Autophagy receptor defects and ALS-FTLD. Molecular and Cellular Neuroscience. 66, 43-52
JOSEPH INNS and VICTORIA JAMES, 2015. Circulating microRNAs for the Prediction of Metastasis in Breast Cancer Patients Diagnosed with Early Stage Disease The Breast. 24(4), 364-9
DE BROT S, NTEKIM A, CARDENAS R, JAMES V, ALLEGRUCCI C, HEERY D, BATES DO, ODUM N, PERSSON JL and MONGAN NP, 2015. Regulation of vascular endothelial growth factor (VEGF) in prostate cancer. Endocrine-related cancer. 22(3), R107-23
INNS J and JAMES V, 2015. Circulating microRNAs for the prediction of metastasis in breast cancer patients diagnosed with early stage disease. Breast (Edinburgh, Scotland). 24(4), 364-9
FOXLER, D.E., BRIDGEM, K.S., JAMES, V., WEBB, T.M., MEE, M., WONG, S.C.K., FENG, Y., CONSTANTIN-THEODOSIU, D., PETURSDOTTIR, T.E., BJORNSSON, J., INGVARSSON, S., RATCLIFFE, P.J., LONGMORE, G.D. and SHARP, T.V., 2012. The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity Nature Cell Biology. 14(2), 201-208
GONZALEZ-ESTEVEZ, C., FELIX, D. A., SMITH, M. D., PAPS, J., MORLEY, S. J., JAMES, V., SHARP, T. V. and ABOOBAKER, A. A., 2012. SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians: PLoS Genet PLoS Genet. 8(3), e1002619
JAMES V, WONG SCK and SHARP TV, 2012. MicroRNA-mediated gene silencing: are we close to a unifying model? Biomolecular Concepts. 3(1), 29-40
JAMES V, WONG SC and SHARP TV, 2012. MicroRNA-mediated gene silencing: are we close to a unifying model? Biomolecular concepts. 3(1), 29-40
FOXLER, D.E., JAMES, V., SHELTON, S.J., VALLIM, T.Q.D.A., SHAW, P.E. and SHARP, T.V., 2011. PU.1 is a major transcriptional activator of the tumour suppressor gene LIMD1 FEBS Letters. 585(7), 1089-1096
BHATTI, I., LEE, A., JAMES, V., HALL, R. I., LUND, J. N., TUFARELLI, C., LOBO, D. N. and LARVIN, M., 2011. Knockdown of microRNA-21 inhibits proliferation and increases cell death by targeting programmed cell death 4 (PDCD4) in pancreatic ductal adenocarcinoma: J Gastrointest Surg J Gastrointest Surg. 15(1), 199-208
JAMES, V., ZHANG, Y., FOXLER, D.E., DE MOOR, C.H., KONG, Y.W., WEBB, T.M., SELF, T.J., FENG, Y., LAGOS, D., CHU, C.-Y., RANA, T.M., MORLEY, S.J., LONGMORE, G.D., BUSHELL, M. and SHARP, T.V., 2010. LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing Proceedings of the National Academy of Sciences of the United States of America. 107(28), 12499-12504
NASIM, MT, GHOURI, A, PATEL, B, JAMES, V, RUDARAKANCHANA, N, MORRELL, NW and TREMBATH, RC, 2008. Stoichiometric Imbalance In The Receptor Complex Contributes To Dysfunctional Bmpr-Ii Mediated Signalling In Pulmonary Arterial Hypertension Human Molecular Genetics. 17(11), 1683-1694
JAMES, V. *, ALDRED, M. A. *, MACHADO, R. D.*, MORRELL, N. W. and TREMBATH, R. C., 2007. Characterization of the BMPR2 5'-untranslated region and a novel mutation in pulmonary hypertension: Am J Respir Crit Care Med Am J Respir Crit Care Med. 176(8), 819-24
LONG, L, MACLEAN, MR, JEFFERY, TK, MORECROFT, I, YANG, XD, RUDARAKANCHANA, N, SOUTHWOOD, M, JAMES, V, TREMBATH, RC and MORRELL, NW, 2006. Serotonin Increases Susceptibility To Pulmonary Hypertension In Bmpr2-Deficient Mice Circulation Research. 98(6), 818-827
MACHADO, RD, ALDRED, MA, JAMES, V, HARRISON, RE, PATEL, B, SCHWALBE, EC, GRUENIG, E, JANSSEN, B, KOEHLER, R, SEEGER, W, EICKELBERG, O, OLSCHEWSKI, H, ELLIOTT, CG, GLISSMEYER, E, CARLQUIST, J, KIM, M, TORBICKI, A, FIJALKOWSKA, A, SZEWCZYK, G, PARMA, J, ABRAMOWICZ, MJ, GALIE, N, MORISAKI, H, KYOTANI, S, NAKANISHI, N, MORISAKI, T, HUMBERT, M, SIMONNEAU, G, SITBON, O, SOUBRIER, F, COULET, F, MORRELL, NW and TREMBATH, RC, 2006. Mutations Of The Tgf-Beta Type Ii Receptor Bmpr2 In Pulmonary Arterial Hypertension Human Mutation. 27(2), 121-132
ALDRED MA, VIJAYAKRISHNAN J, JAMES V, SOUBRIER F, GOMEZ-SANCHEZ MA, MARTENSSON G, GALIE N, MANES A, CORRIS P, SIMONNEAU G, HUMBERT M, MORRELL NW and TREMBATH RC, 2006. Bmpr2 Gene Rearrangements Account For A Significant Proportion Of Mutations In Familial And Idiopathic Pulmonary Arterial Hypertension. Human Mutation. 27(2), 212-3
JAMES V*, MACHADO RD*, SOUTHWOOD M, HARRISON RE, ATKINSON C, STEWART S, MORRELL NW, TREMBATH RC, ALDRED MA., 2005. Investigation of second genetic hits at the BMPR2 locus as a modulator of disease progression in familial pulmonary arterial hypertension. Circulation. 111(5), 607-613


text:
Q: Is there a way to get the readability stats for a Word document without going through grammar & spelling check (on a Mac)? As far as I can see, the only way to get the readability statistics for a document (or a selection in a document) is to start the "Spelling & Grammar" tool, go through all the spelling and grammar issues, and then finally landing on the Readability Statistics page. Is there any way to just jump right to Readability Statistics?  For a huge doc with lots of unrecognized words (in this case, lots of code and java class names) it is so tedious to get through the entire spelling and grammar process.
Note: I am using Microsoft Word for Mac 16.16.20 (200307).

A: You need a VBA macro to display these values without completing the spell check.
VBA seems to be supported on MacOS.
The document should be first saved as .docm to allow macros, then use
Alt+F11 to enter the VBA editor, use menu Insert > Module
and set the contents to the following:
Sub Readability()
    Dim DocStats As String
    DocStats = ""
    For Each stat In ActiveDocument.Content.ReadabilityStatistics
        DocStats = DocStats & stat.Name & " : " & stat.Value & vbCrLf
    Next stat
    MsgBox DocStats, vbOKOnly, "Readability Statistics"
End Sub

You may use F5 in the editor to run/test the macro.
In everyday use you may run the macro from the
Developer tab
or
Assign a macro to a ribbon button
or do
Adding a Macro to the Quick Access Toolbar.
Remember to run the spell-check first, before testing the macro.
Reference: Only Showing Readability Statistics.

redpajama_set_name: RedPajamaStackExchange


text:
Latest Songs From Eric Church Written Before The Pandemic
Country Music Videos
Eric Church has been treating fans to several new songs over the past few months, including "Crazyland," "Through My Ray-Bans" and most recently, "Doing Life With Me."
While these songs may sound like they were inspired by the global pandemic, they were all written before that began.
Eric talked about the songs late last year at the CMA Awards.
"We made this project before COVID ever existed. So, for me, we never came in reacting to COVID. We made this project, we wrote this project, we recorded this project before we ever knew what COVID was. I think a lot of that is a little bit divine that if you listen to the songs and you hear what the songs are, you very easily go, 'This sounds like they were in the middle of quarantine,' but we weren't."
Eric's recently-released songs were penned during a marathon writing session held at a rural North Carolina cabin.
He recorded a song from start to finish each day for nearly a month.


A small, spreading deciduous tree which has bronze-red young leaves that turn dark green before turning shades of orange and red in autumn. The large, double flowers are pink in bud, turning white as they open in the late spring, turning pink again before they fall.
Soil: It thrives in free draining soil.
Suitable Locations: parks, verges, small gardens.


text:
Die Amerikanische Brandseeschwalbe, jetzt Cayenneseeschwalbe (Thalasseus acuflavidus, Syn.: Sterna acuflavida; Thalasseus sandvicensis acuflavidus) ist eine Vogelart aus der Unterfamilie der Seeschwalben (Sterninae).

Sie kommt auf den karibischen Inseln und entlang der Küsten des Atlantischen und Pazifischen Ozeans in Nord- und Südamerika vor.

Beschreibung
Der Vogel ist 36–46 cm groß und wiegt 175–202 g.

Die Amerikanische Brandseeschwalbe ist der Brandseeschwalbe sehr ähnlich, unterscheidet sich  durch einen längeren und dünneren Schnabel mit gekrümmter Schnabeloberkante (culmen), Scheitel und Stirn sind leuchtend weiß, nicht grau. Der hinten breitere Augenring ist deutlicher, an den äußeren Handschwingen finden sich kleine Haken.

Lebensweise
Die Nahrung besteht aus Fischen.

Geografische Variation
Es werden folgende Unterarten anerkannt:
 T. a. acuflavidus (, 1847), Nominatform – östliches Nordamerika bis südliche Karibik, überwintert in Peru und Uruguay
 T. a. eurygnathus (, 1876) – Insel vor Venezuela und Guyanas, Norden und Osten Südamerikas

Artstatus
Bis vor kurzem wurde die Amerikanische Brandseeschwalbe als Unterart der Brandseeschwalbe angesehen, so Avibase, IUCN Redlist und Handbook of the Birds of the World.

Im Jahre 2011 empfahl die British Ornithologists' Union die Abspaltung als eigenständige Art.

2015 erfolgte durch die Association of European Rarities Committees die Empfehlung zur Abspaltung.

In der IOC World Bird List der International Ornithological Union ist diese Auftrennung bereits berücksichtigt.

Die Amerikanische Brandseeschwalbe ist näher mit der Schmuckseeschwalbe verwandt.

Literatur
 M. Garner, I. Lewington, J. Crook: Identification of American Sandwich Tern. In: Dutch Birding Bd. 29, S. 5, 2011

Einzelnachweise

Weblinks

 Oiseaux.net

Seeschwalben


text:
package support

import (
	"github.com/aerogo/aero"
	"github.com/animenotifier/notify.moe/arn"
	"github.com/animenotifier/notify.moe/components"
)

// Get support page.
func Get(ctx aero.Context) error {
	user := arn.GetUserFromContext(ctx)
	profileLink := "/"

	if user != nil {
		profileLink = "/+" + user.Nick
	}

	return ctx.HTML(components.Support(profileLink, user))
}

redpajama_set_name: RedPajamaGithub


text:
Ferrari Hoping Final Podium builds Momentum into 2017
Throughout the 2016 season, Ferrari have been under immense pressure to win a race again in Formula One. They got close on occasion, but ultimately missed out on getting Vettel or Raikkonen on the top-spot.
Despite not winning and being cast into crisis for sensational purposes, the Italian team have had a campaign littered with podiums and top-six performances. Red Bull managed to exceed expectations and grab 2nd in the Constructors by 70-points despite Christian Horner's first race hopes of simply "finishing in the top five".
Brilliant #Seb5 #AbuDhabiGP 👊🏼🏎 pic.twitter.com/PLl16BQoL4
— Scuderia Ferrari (@ScuderiaFerrari) November 27, 2016
There is a cliff edge and big drop off to Force India in 4th. Whilst their efforts this season have been immense in beating Williams, Perez and Hulkenberg would have needed more than double their points tally to beat Ferrari.
Sebastian Vettel endured a few incidents on his travels. His power-unit gave up on the formation lap of Bahrain, a double-tag at the start in Russia and a dramatic tyre blowout in Austria were the most notable misfortunes. It prevented him from having a chance in beating Daniel Ricciardo, who scored two more podiums than Vettel with no retirements throughout the year. A stroke of luck but mainly a personal purple patch of form for the paddock's own Honeybadger.
2014: 238 points and a stellar debut year with the Team 👏
2016: 256 points and a personal best #F1 tally! 🙌 #givesyouwings @danielricciardo pic.twitter.com/FRL7oabLCo
— Red Bull Racing (@redbullracing) November 29, 2016
The drama between the Mercedes drivers at the Abu Dhabi Grand Prix overshadowed the solid drive from Vettel, who has a strong record around Yas Marina. After claiming his 6th podium of the year, Vettel said,
"I think it was an important race for us today: in the final laps, I would have liked to gain two more positions, because the speed was there; but it was difficult to make the move because the car in front also benefited from a tow. Nevertheless as a team we deserve this podium, and I hope it gives some momentum to all of us. It has been a tough year, with lots of up and downs, so I am really happy with this result.
About our global performance in 2016, I think we don't need to find any story or invent something. I think we expected more; but after the first half, where we could have scored more points, I think we showed real strength by coming back. In the last couple of Grand Prix we had very good race pace, always enough to match Red Bull, and probably even a bit quicker: but that was not the case on Saturdays, and that made Sundays more difficult. Overall we showed the stamina that the team has.
The spirit is unbroken, and I know that we will work hard, because Ferrari deserves to come back. All in all we learned a lot, we made a lot of progress. Today is Nico's day, well done to him. I think you don't win the Championship by luck, and it is a sign of respect to give him this. He is a deserving champion."
– Sebastian Vettel
END: Great race from #Seb5 P3 and #Kimi7 P6 #AbuDhabiGP 👏🏼👏🏼 pic.twitter.com/tsgKKs5ACe
The team have consistently fallen short in Qualifying, but have more often than not gained ground at the race-start. The team can go into 2017 in the knowledge that this year's regulations might allow them to close the gap to Mercedes more than last year's stable changeover.


text:
Kaitlin Huwe
Selected Scenes
Photo by Lea Lilly Guillory
Born and raised in the California Bay Area, Kaitlin Huwe is an actress and singer-songwriter with an affinity for shape-shifting, traveling back in time, and offering songs and stories as medicine.
Television credits include TNT's drama series, Animal Kingdom, directed by John Wells, recurring in flashbacks as Ellen Barkin's young mother in the 70's, and starring alongside Adam Devine in Comedy Central's Workaholics.
Kaitlin plays 'Daisy', a quirky and soulful meditation teacher, in the award-winning independent feature film Deany Bean is Dead an Official Selection at Dances with Films Festival, Long Beach Indie Film Festival, Ojai Film Festival, Valley Film Festival, Cambria Film Festival, and Strasberg Film Festival.
Kaitlin is a proud member of The Road Theatre Company, which exclusively produces new plays that are socially and politically relevant. She recently originated the role of 'Samantha' in the World Premiere of Through the Eye of A Needle by Jami Brandli.
Kaitlin also works closely with Sketch Comedy and Music Group Hot Chocolate Party and can be seen guest starring in many of their viral videos.
When she is not acting, she writes music for live theater, film, web content, and to stay sane. She recently released a single "The Old Man and His Daughter" produced by Joel Henry Stein, at Green Zebra Records. Monica Payne directed the music video, shot on location in rural Illinois. She is currently recording her new single "King Size Bed."
Kaitlin earned a BA in Acting from UCLA School of Theater, Film, and Television, completed the Advanced Improv Track at The Groundlings School, in LA, and is a graduate of the 2-Year Meisner Training at the Joanne Baron / D.W. Brown Studio.
She has infinite love for swimming in large bodies of water, roaming museums, photographing trees, eating chips and salsa for dinner, taking road trips, collecting candles, practicing and leading yoga, following the moon, rocking babies to sleep, drinking hot tea, listening to poetry read aloud, and feeding her friends.
Join Kaitlin's Newsletter
RECEIVE UPDATES ON LIVE SHOWS, NEW RELEASES, & PERSONAL NOTES FROM KAITLIN


text:
Q: Give column number of first column with symbol So say I have a sheet like the following:
Row    1    2    3    4    5    6
1      x
2           x
3      x         x
4                     x
5           x              x
6                               x

And I have another sheet which I want to encapsulate the data with:
1st appeared
1
2
1
4
2
6

I'm basically trying to construct the second sheet. Is there a way for each row to start at column two and go up to the ith column and display where the first 'x' appears. (Note that we can assume that every row will have at least 1 'x' when the row and column meet forming a diagonal down the entire first sheet) [Note that my first spreadsheet is roughly 5,000 x 5,000 hence why I'd like a nice formula for this instead of doing things by hand =)]
Thanks in advance!

A: The MATCH function return the relative position in either a row or column. Use this formula in your second worksheet.
=iferror(match("x", sheet1!1:1, 0) - 1, 0)

Fill down to retrieve the correct column index or zero if not found. A 1 is subtracted since hte want the position relative to column B. The IFERROR function return a default 0 is no match is found. Substitute "" in place of the zero if you want nothing displayed.


It's Clara who's desperate to enter the labyrinth and it's Clara who's bright, strong and fearless enough to take on any challenge. It's no surprise when she's chosen. But so is the girl who has always lived in her shadow. Together they enter. Within minutes, they are torn apart forever. Now the girl who has never left the city walls must fight to survive in a living nightmare, where one false turn with who to trust means a certain dead end.
Caighlan Smith wrote her first novel when she was fourteen and has been writing ever since. A lover of mythology and gaming, Smith studied English Literature, Classics, and Creative Writing at Memorial University of Newfoundland. The "gh" in her name is silent. Smith wrote Hallow Hour, Book One in the Surreality series, in her final year of high school. Smith is currently working on the sequel to her newest YA Fantasy novel, Children of Icarus, which has won the Scottish Teenage Book Prize 2018!


text:
Happy St. Patrick's Day!
in Nerdkram
Süß, oder? 🙂
To celebrate St. Patrick's Day, today's Doodle takes us to the mystical Skellig Michael, a remote island just off the coast of County Kerry, Ireland. The breathtaking destination is a World Heritage Site and home to many species of seabirds — like puffins, gannets, and razorbills — that perch atop the island's summit. If you're brave enough to scale the 600 steps to the top of the rocky precipice, you'll see a magnificent view of the mainland and the Atlantic Ocean from 714 feet above sea level. The Skelligs are part of the Kerry Gaeltacht, where locals speak Irish, and you may hear "céad míle fáilte," or "a hundred thousand welcomes," if you visit.
Bonus draft! Just for fun 🙂
Skellig Michael appeared on the big screen in 2015, and since then, more and more people have been coming to take in the stunning scenery. Just for fun, Doodler Matt Cruickshank explored the island's cinematic claim to fame. He says, "I thoroughly enjoyed populating this magical island with shamrock people, even one from a shamrock galaxy far, far away."
Quelle: https://lh3.googleusercontent.com/Dj4YdohNnTGswWi2h8nutTX4HMUpRiuGcZ8Sk1_NNoZRdvtUgIg1CJmY5vMber4Hx491j4-P2GrW5tsyMGoCqcM63xti9RAR6Dx0NXSM=s0
Torment: Tides of Numera


text:
Q: C++ How to Implement Menu with Number and Letter Choices I want to use a menu in C++ that has options both in letters and numbers.  For example, the output might be:
========================
(1) Do something
(2) Do something
(a) Do something
(b) Do something
========================

Is there a method for testing user input to determine if it is a char or int and handle it accordingly?
If I use:
int choice;
cin >> choice;

And the user inputs a char, of course cin will return an error.  I'm looking for a simple method to test user input for a digit or a character and have the program react differently based on that determination.
[UPDATE]
I've found the answer I was looking for.  Here's how I did it:
string choice;
cout << "Your choice: ";
cin >> choice;

if( isdigit(choice[0]) )
{
    theInt = stoi(wChoice);
    // do something with int
}
else if( choice[0] = 'a' )
    // do menu option a

A: You'd better use the method isdigit in the ctype.h to check if character is a decimal digit character, and the method isalpha to check if character is alphabetic.

A:
"For example, there could be options: 1, 2, 3, n, s."

The simplest solution I see is to have a menu selection code like
char choice;
std::cin >> choice;

switch(choice) {
case `1`:
   // Do menu option one
   break;
case `2`:
   // Do menu option two
   break;
case `3`:
   // Do menu option three
   break;
case `n`:
   // Do menu option "n"
   break;
case `s`:
   // Do menu option "s"
   break;
}

If you need to handle numeric choices bigger than 9, you simply use a std::string as input field:
std::string choice; // <<<
std::cin >> choice;

in turn a switch statement cannot be used any more and you have to change it to an if/else if/else cascade:
if(choice == "1") {
   // Do menu option one
}
else if(choice == "2") {
   // Do menu option two
}
// ...
else if(choice == "42") {
   // Do menu option fortytwo
}
else if(choice == "n") {
   // Do menu option "n"
}
else if(choice == "s") {
   // Do menu option "s"
}

A: For this, you'll need to read in the input as a string, then parse it to see if it's an alphabetic character or if it's a numeric string.  Something along the lines of this (warning, I'm mostly a C programmer, so using C-strings instead of real strings):
#define INPUT_SIZE 8
char input[INPUT_SIZE]; // change size as appropriate
cin.getline(input, INPUT_SIZE);

if (cin.good())
  if(input[0] >= '0' && input[0] <= '9') {
      int value = atoi(input);
  } else if(input[0] >= 'a' && input[0] <= 'z') {
      char value = input;
  }
}

Naturally, values need different names and actual code paths to deal with them, especially as C++ doesn't have a good built-in "either" type that I know of.
Alternatively, just treat everything as a character, assuming all numeric options are a single character, and test as '0' instead of 0.


New ringers are always welcome.
Have YOU ever thought you might like to become a bell ringer?
We are urgently seeking new recruits who would like to learn how to ring bells.
Just turn up at a Thursday practice and introduce yourself!
Sidbury tower has eight bells, the earliest dating from 1662 and 1663. Six more were hung in 1712, 1750, 1752, 1776 and two in 1947 to complete the present eight.
The Captain of Bellringers is Andrew Clarke and Sidbury has a small band of enthusiastic ringers, usually enough to ring five or six of the bells at Sunday services and weddings.
Bell ringing practice is on Thursdays at 7.00 pm, except for the second Thursday in any month when The East Devon Guild of Ringers use the tower.


The print aggregation models of today and tomorrow are by nature both digital and virtual. And the rise of "Augmented Reality" in print is a natural evolution for gaining more benefits from print aggregation. As evidence of this new reality in print, the CBS broadcast network advertised its fall TV season with a video-chip ad embedded in an issue of Entertainment Weekly. The September 18 issue of the Time Inc. owned magazine featured the first video ad to appear in print and it certainly will not be the last. The print aggregation model is ideally suited to integrate these interactive technologies and print production by putting all the relevant vendors into a single database. While the exact details of the future of Augmented Reality are not clearly known today, print aggregation assures that wherever the technological breakthroughs are, they will be visible and accessible through print aggregation software.
"As we look back at 2009, a technology milestone for the printing industry, marketing communications, education, and the media world may be the rise of augmented reality. Augmented reality (AR) is a field of computer science that involves combining the physical world with an interactive, three-dimensional virtual world. This term might be new to some of you, but augmented reality makes print the ultimate in interactive media. Engaging customers with print is sometimes difficult, but augmented reality is popping up everywhere to drive product sales, get people to open magazines, and enhance the educational experience associated with books.
In November, Danish toy manufacturer LEGO launched its "DIGITAL BOX" in selected toyshops and LEGO stores worldwide. This interactive terminal utilizes innovative technology supplied by Munich-based augmented reality expert Metaio in the form of a software program specially developed for the LEGO Group. Together with a camera and display screen, the software enables a LEGO package to reveal its contents fully assembled within live 3-D animated scenes.
In today's buyers' market, purchasing decisions are often driven by consumer excitement about a product. This certainly applies to the toy market. Ideally, consumers will want to hold a potential purchase in their hands and look at it closely from all angles, but this can be difficult when the product is composed of individual pieces. For example, consider construction toys—even if you opened the box right away, it would take hours to find out what the toy looked like when it was assembled. The DIGITAL BOX from LEGO provides a solution. Parents and children can hold special LEGO boxes (containing a hydraulic digger or police station, for example) up to an interactive kiosk to see a 3-D animation of the assembled product superimposed on the box.
It's interesting that this version of the right size for a printing company is based on data that is prior to 2008. With the printing industries' adoption of print aggregation models, the right size becomes highly dynamic and should be answered with "it depends". It depends on how effectively a printing company can integrate print aggregation technology into their business model. Suffice to say, the right size has little to do with the number of employees and everything to do with the amount of sales revenue generated for the business.


Looking to learn how to keep a conversation going?
I help people get the advanced social skills they need, to get what they want out of life. The very best way to ensure that you achieve the life of your dreams is to learn to be good with people. I'm glad you're here.
Download One of My Powerful Cheat Sheets.
Through his best-selling social courses (The Social Invincibility Program and The Vocal Power BOOTCAMP) and top-ranked YouTube Channel, Barron inspires the realization of "Wow! I really CAN become charismatic" to tens of thousands of people every day.
He accomplishes this by staying away from 'old school theory' and broad concepts. Instead, he coaches everyone, from the most shy and introverted folks to those who are naturally outgoing with step-by-step processes and techniques that can be immediately implemented. This creates quick momentum as participants feel real improvement and begin to see what their life could be like as they continue to learn and improve.
Live demonstrations, real social interactions and easy to understand examples are all captured with UHD 4k cameras and Hollywood film quality microphones.
With millions of views, Barron's channel has created a buzz for countless result driven, ambitious viewers like you.


text:
Q: Efficient conversion of a ByteArray object into a hexadecimal string What is the best way to convert ByteArray objects into hexadecimal string representation? Although the following works, I find it questionably awkward (and likely not very efficient):
ByteArray[{9, 182, 236, 38, 171, 0, 236, 56}] //
 StringJoin@IntegerString[Normal@#, 16, 2] &

"09b6ec26ab00ec38"

I contrast this complication with BaseEncode which directly converts ByteArrays to Base64 encoding.
(EDIT: Sure, considering the shortness of the solution one might consider this question a sort of a thinly veiled feature request! Still, I'm curious of any better alternatives.)


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High Radiation Levels Found in Giant Clams Near U.S. Nuclear Dump Site on Marshall Islands
A Tiny Island Used as a Nuclear Dumpsite Is About to Be Submerged by Water
World Leaders to Trump: You're on Your Own
The 100-meter wide crater on Runit Island was deemed a good place to dump as much soil contaminated with plutonium as possible. Chunks of unexploded plutonium-239 were also disposed of in the hole. Google Earth
New research found high levels of radiation in giant clams near a 42-year old nuclear waste site in the Central Pacific. The findings have scientists concerned that pollution from the site is leaving the enclosed structure and leaking into the ocean and the food chain, according to the Los Angeles Times.
Radioactive Shellfish Found Near U.S. Nuclear Dump Site on ... ›
High radiation levels found in giant clams near U.S. nuclear dump in ... ›
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By Joe McCarthy
The Enewetak Atoll is all but invisible on Google Maps. Halfway between Australia and Hawaii, the ribbon of land is home to a small indigenous population that has seen their way of life eroded by decisions far outside of their control.
For more than half a century, the atoll, which is part of the Marshall Islands, has been contaminated by nuclear explosions and waste, according to ABC Australia. The decades ahead could leave it submerged by rising sea levels.
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Greenpeace activists in Berlin projected an image of Donald Trump on the U.S. Embassy. Michael Sohn / DPA
The overwhelming global response to President Donald Trump's decision to pull the U.S. out of the Paris climate agreement was essentially, "Go jump in a lake"—or as one Germany tabloid succinctly phrased it in a widely circulated headline:
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Pacific Island Leaders Adopt Game-Changing Climate Policy
Leaders from some of the world's most vulnerable climate countries have today adopted the Majuro Declaration calling for a "new wave of climate leadership" and marking the region's efforts to accelerate action.
Issued at this year's Pacific Islands Forum, which took place on the Marshall Islands, the declaration calls on countries to list specific, concrete pledges to reduce emissions and aims to accelerate the global response to the climate crisis.
The Pacific islands represent many of the countries most at risk by climate change, and they used the latest summit highlight the threats it places on security, livelihoods and the well-being of their populations, as well as those of other vulnerable nations across the globe.
Also signed by Australia and New Zealand, the declaration highlights the region's own commitment to tackling climate change.
Speaking after the adoption of the Majuro Declaration, President of the Marshall Islands, Christopher Loeak said:
We want our Majuro Declaration for Climate Leadership to be a game changer in the global fight against climate change. Forged on the frontlines of climate change's devastating impacts, we hope it gives new impetus and accelerates the transition to the low-carbon economy.
We've had a strong meeting of minds here on the urgency of the problem, but the real work begins now. We need the rest of the world to follow the Pacific's lead. I look forward to making that case during meetings with fellow leaders at the UN General Assembly in New York later this month.
As chair of the Pacific Islands Forum for the next 12 months, my absolute priority will be to fight for a safe climate future for my people, the Pacific region, and indeed the entire world. We must seize this moment, and rededicate ourselves to ensuring that a new wave of climate leadership takes hold.
As part of the declaration, Pacific island nations made their own pledges to combat climate change. For example, host country, the Marshall Islands pledged a 40 percent reduction in carbon dioxide (CO2) emissions—below 2009 levels—and 20 percent indigenous renewable energy by 2020.
Tuvalu and the Cook Islands both pledged to supply 100 percent of their countries' energy by 2020, while Paupa New Guinea pledged to become carbon neutral before 2050.
They also highlighted the intense frustration felt by many island nations over the sluggish progress of other countries to cut their greenhouse gas emissions.
A post-forum dialogue will now take place to encourage the 13 dialogue partner countries—including the EU, the U.S. and China—to sign on to the declaration, and submit their own climate commitments, ramping up action both in the Pacific region and globally.
The declaration will then be presented to the UN Secretary-General Ban Ki-moon during this year's General Assembly Leaders' week, taking place in New York this September.
The Majuro Declaration for Climate Leadership
130905 RMI PIF Majuro Declaration + Commitments
Visit EcoWatch's CLIMATE CHANGE page for more related news on this topic.
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