California Natural Sliced Blanched Raw Almonds.
Our all-natural sliced and blanched bulk almonds will add a heart-healthy crunch to any baking project, recipe or garnish that your heart desires. These high-protein, low-carb blanched almonds are sliced to perfection and are the perfect addition to any snacking or baking need you may have. Throw handfuls in salads, cookies, cakes or home-made granola to add nutritional value and healthy fats. Or, take them along with you during the day to pop in your mouth for juicy, sweet almond snacks that you can enjoy at any time of the day. Our bulk sliced and blanched almonds are delicious and good for you - they are low in sodium and cholesterol. Choose from several packaging sizes - including a sample size. Bulk pricing applies to large orders, so you are guaranteed to save big on these premium-quality bulk sliced and blanched almonds.
I use the almonds often in baking one of my family's favorite items...Almond Tea Ring. The bulk price allows me to really embelish this item.
These sliced blanched almonds are a total pleasure to look at, eat, and cook with.
Baking of numerous recipes from coffee cakes to encrusted chicken. The quality and price have encouraged exploring many uses.
I use 10 pounds of almonds every 6 weeks or so and these are the best almonds I've found. Always fresh, high quality and very tasty. I use them both for baking and, as I have a small bird sanctuary, as treats for the birds. These are exceptionally good almonds.
Bake numerous stollen as holiday gifts. Previously I have used slivered almonds from Oh Nuts. During the kneading process, these broke up. Decided on a new approach this year using slivered almonds, which I toasted. I added the almonds by hand after machine kneading. Works great!
trying to add variety to my birds' diet and to use te as a training treat, i discovered how tasty and crunchy these sliced almonds are and how they perk up my own menu when added to yogurt, veggies, salads, ice cream, and cereal. my cockatoo, my and i enjoy the taste, the crunch, and the quilt-free nutrition.


Montagne Jeunesse have recently launched their new range of 'Tottles' (think a mix between a bottle and a tube) which allows for up to 10 applications of face masques and peel-offs. They're a perfect pick-me-up and as part of a beauty regime. The ethos behind the brand is they are animal friendly and are strongly against animal testing and their products are lovingly made with on the purest, natural ingredients that are responsibly and ethically sourced.
I enjoy nothing more than relaxing in a bath and putting on a face mask and these new tottles are perfect as sometimes the sachet masks can be a little messy to apply. I was kindly sent a few masks to try out myself which I did over the weekend and they smell amazing - the chocolate one smells EXACTLY like Terrys Chocolate Orange and good enough to eat! There is a warning on the back on the packaging not to eat it, I was tempted to try it haha! I really enjoyed using the spicey warming mask that opens up the pores, my skin felt so clean and refreshed afterwards.
Renowned for its cleansing and super hydrating properties, delicate Damask Rose is infused with Africa's miracle Marula oil to rid of anti-oxidants and seriously moisturise. Then the Shea Butter and Cocoa Butter join forces to soften and smooth for enviable silky skin. The lovely fresh floral fragrance is a damask delight. A lovely mask to use on sensitive skin or older skin (my mum loves this!).
Indulge in divine, dark chocolately orange bliss where moisturising Cocoa and Shea Butters combine with sweet Orange Oil, to deeply cleanse and nourish. Did you know that orange is jammed packed full of anti-oxidants which help protect skin from free radicals that bring on the signs of ageing? This ultra rich wonder masque smells like heaven on earth and is not to be missed when it comes to spoiling your skin.
Get cosy and comfy with this irresistibly spicy warming masque that heats up and opens pores, ridding skin of any nasties in an instant. A gorgeous and exotic blend of Cinnamon, which brightens and tightens, and uplifting Ginger, will leave your skin radiant and deep-pores cleansed.
The New Montagne Jeunesse Tottles are available from http://www.superdrug.com/ and http://www.montagnejeunesse.com/ priced at £4.99 each.
I wish they had those where I live! Currently on my wishlist now!
I would love this, I'm sure of that.. but unfortunately it's not available where I live.. bah!
Going to hunt these down! Must have them!


71 Various Photos Of Red White and Blue Patio Lights.
Hello, Looking for inspirations of red white and blue patio lights, here we have saved 71 images about red white and blue patio lights for your guides in making home outdoor decor.
Decorate this 4th of july with patriotic red white and blue lights show your pride with american flag themed led string lights window decorations & more. Oogalights offers a full selection of patriotic red white and blue lights from globe lights string lights galaxy lights patio umbrellas & accessories. Devida patriotic red white blue solar string lights decorations outdoor memorial day 4th of july decor waterproof 100 mini 2 mode led strand set for patio tent. Patio string lights cart cart is empty view cart checkout home 70 5mm blue red cool white led christmas lights 4" spacing better than expected. Find great deals on ebay for red white blue lights in garden lanterns and light strings shop with confidence. Red white and blue patriotic lights add sparkle july with patriotic lights red white and blue or patio overhang red white and blue lights surrounding. Let our 8 show stopping patriotic lighting ideas inspire red white and blue lights in your summer holidays.
Browse inspirations about red white and blue patio lights in the gallery bellow. We hope you love the ideas, please spread with your friends.


Filled up form has to be sent back to us with a DD of Rs. 1000 in the name of ABIT-PMCA payable at Cuttack along with the following documents.
Attested xerox copies of 10th & 12th marksheets & certificates.
Migration/ Transfer certificate( only xerox now).


Does this song provide a glimpse as to why as some say Stevie couldn't continue to work with Lindsey?
Or, $he said to Mick.. I'm never touring with him again and Mick fired LB.
Lindsey is a genius producer, not a miracle worker.
You mean when he takes a boring song interesting? Mike Campbell and her write ok songs together that have ZERO artistry in the production. Not the reason I became a fan.
She couldn't work with Lindsay anymore because she thinks her songs are perfect as is… They are not. She has found people who will take her demos and verbatim transcribe them and they come off as very boring to me.
Because he hurts her everything? Sounds about right.


A fresh Korean favorite with the flavor of kim chi. Enjoy with a bowl of rice.
Bring a large pot of lightly salted water to a boil. Add the bean sprouts, and cook uncovered until tender yet still crisp, about 15 seconds. Drain in a colander, then immediately immerse in ice water for several minutes until cold to stop the cooking process. Once the bean sprouts are cold, drain well, and set aside.
Whisk soy sauce, sesame oil, chile powder, garlic, and sesame seeds together in a large bowl. Stir in bean sprouts and toss until well coated with the sauce. Sprinkle with green onions and season with rice wine vinegar.


Rainbow Trust Children's Charity provides support to families who have a child with serious illnesses.
Today there are an estimated 49,000 children and young people in the UK living with a life-limiting or life-threatening condition who may require palliative care (University of Leeds, 2011). Many of these children and their families are able to cope or are not in a 'crisis situation'. However, thousands of families have to face the very real possibility that their child may die and struggle to cope on a day to day basis.
Rainbow Trust supports these families who have a child with a life-threatening or terminal illness and are in the greatest need. Their Family Support Workers provide a lifeline to these families and children. They support the whole family including parents, carers, the unwell child, brothers, sisters and grandparents. They bring support and help to families who so desperately need it at home, in hospital and in the community. Any family can receive support from the moment of their child or young person's diagnosis.
Maintaining school attendance, cinema trips, days out at the zoo and general fun and laughter.
Emotional support, respite, countless meals cooked, baths run and storybooks read.
Helping to organise appointments, explaining illness and treatment, looking after siblings and staying with sick children in hospital.
For the entire family: parents, grandparents and siblings, face-to-face and over the phone, at any time of the day or night.


text:
Q: How i get live admob id to my android app? activity_main.xml
public class MainActivity extends AppCompatActivity {

private AdView mAdView;
private Button btnFullscreenAd;

@Override
protected void onCreate(Bundle savedInstanceState) {
    super.onCreate(savedInstanceState);
    setContentView(R.layout.activity_main);

    mAdView = (AdView) findViewById(R.id.adView);
    AdRequest adRequest = new AdRequest.Builder()
            .build();
    mAdView.loadAd(adRequest);

A: To set the ad unit id of your ad you want to display to your live id from Admob, add this line of code before you create an ad request and load an ad: bannerAd.setAdUnitId(YOUR_LIVE_AD_UNIT_ID);. Change the YOUR_LIVE_AD_UNIT_ID to your ad unit id from your admob ad unit.
If you want to test your ads, you shouldn't use your live id until you are publishing your app. For Banner Ads, use ca-app-pub-3940256099942544/6300978111 and for interstitial ads, use ca-app-pub-3940256099942544/1033173712
Hope this helps!

redpajama_set_name: RedPajamaStackExchange


Ask your closest friend or a loved one to stand by you on the most important day of your life with this personalised floral T-light holder. Simply add their name of up to 15 characters and their role and the message will read "[NAME], I can't say I do without you. Will you be my [ROLE]?"


You would like to keep your computer organized which means you would want to view your files and folders sorted by name. However, sometimes you would like to sort your folders by kind for a very small period of time and you would revert it back to by Name. Mac OS X Snow Leopard operating system only remember the last sorting method you opted and only allow you to switch between different these types of sorting by manually.
When you check the same option in Mac OS X Lion you will notice that it gives you an option how you want your files arranged and it also remembers your selected arrangement. Not only that, it also allows you to change your sorting arrangement and view it for temporary basis. The next time when you check your files, you will find them sorted back to original method you selected. You must be confused about what we have just talked above, so in order to understand it properly you need to know the difference between an old and new Finder view in Mac OS X Lion.
Mac OS X Lion has brought a new way to arrange your files on temporary basis while viewing them in Finder. This new method is called Clean Up By and you will find this option in Finder View menu. If you go to view menu and then select Clean up by with sub-options: Name, Kind, Date Modified, Date Created, Size or Label. You will notice that your files are temporarily sorted according to your selection.
However, if you want to The sort the files on permanent basis the you have to to choose Arrange By option from the View menu along with its sub-options: Name, Kind, Application, Date Last Opened, Date Added, Date Modified, Date Created, Size, Label or None.


Check out all of festival details and times!
Home Brew Contest, Rules & Entry Forms!
Are you ready to try you hand at competition BBQ? Well we are looking for team to sign up for this years Backyard BBQ contest!
Make sure you get your tickets early and often! Grab a friend, and a drink! Can't wait to see everyone!
Do you want to be a BBQ food vendor? Contact us and submit an application to be part of this years Dekegger!
50 Plus different craft beers on hand to try from. Local breweries will be on hand with tons of different varieties to sample. This is your one stop to wet your whistle.
Looking to enter into our Backyard BBQ Competition? Check out the link below for entry instructions and rules.
Just looking to come out and spend some time listening to great music and enjoying BBQ? Well we have you covered on all fronts, Food Trucks and BBQ vendors will be in attendance to feed the masses.
Don't be left out in the cold, while all your friends attend this years festival. Grab your tickets now. Click the link and grab some VIP Packages while you are at it. Cheers!
Home Brew Competition is limited to the first 50 entries.
Entry fee of $8 per entry required with bottle delivery.
Each entry should include two 12-ounce bottles with a completed bottle label attached to each bottle with a rubber band.
Winners will be announced at the Dekegger Festival.
Private judging will be held on June, 15th 2019.
This is a beer only competition; no meads or ciders will be accepted.
What is a Backyard BBQ Competition?
A Backyard BBQ Competition is for the guys and gals that know everyone likes their grill skills. Maybe they don't have the time or money to go pro like the KCBS competitors but would love a chance to be crowned king or queen of the grill for an entire year. So why not try out those skills on some other backyard BBQ warriors for a chance to win some cash, trophies and more importantly those never ending bragging rights!
*Each entry includes 2 wristbands for the festivities on Saturday. Additional wristbands can be purchased for $20/per person.
* & Trophies of Course!!!
1)	Electric, Pellets, charcoal and wood burning smokers are allowed for amateurs.
Will be blind judging, via turn in boxes.
Download your copy of the rules and application below.
Gavin Lynn and Ryan have been writing together consistently for nearly a year. We've written enough songs to put an album together, and then some. (An album we will be recording very soon btw) My solo hobby as a musician when I started this page is now a group project and we feel it needs a group name. Curiously, finding a name has proven to be one of the most difficult creative tasks we have encountered, but that day has come. I am so excited to move this project forward with Gavin and other musicians we may create with along the way. Same music, different name. :) Stratton Way.
Register & Compete for Cash & Prizes.
A full day of delicious BBQ. come hungry, leave happy!
Let's Get Your Drink On!
For press or vendor inquiries, please send us a message. Thank you for your interest! We will get back to you as soon as we can.
Copyright © 2018 The Dekegger - All Rights Reserved.


text:
Get on Board with the D'arce Choke! – BJJ Fanatics
UFC 239: White rips into Darren Rovell (again) over Nunes comments
July 8, 2019 admin 0 Comments comments, Darren, Nunes, rips, Rovell, UFC, White
Dana White holds grudges? Who'd have thunk it.
The UFC president was coming off a big and highly successful night at UFC 239. Both his champions emerged from their fights winners, with double champ Amanda Nunes scoring a huge higlight reel head kick knockout against Holly Holm. It was just the latest violent finish for Nunes, who has now destroyed a who's who of WMMA from Ronda Rousey to Cris Cyborg and everyone in between.
But for such a destroyer, she hasn't always been given the credit or attention she deserved. You could argue this is because the UFC spent a large amount of the last couple of years under-promoting her, first ignoring her during the build-up to her fight with Ronda Rousey and then actively burying her after she pulled out of a bout on fight weekend due to a flare up of sinusitis.
But as willing as Dana White has been to throw any of his stars or would be stars under the bus should they cross him, he's also strangely protective of them as well. When Nunes knocked out Cris Cyborg in December of 2018, former ESPN business analyst Darren Rovell drew his ire for suggesting it was bad business for Nunes to win.
Between Rousey and Cyborg, Amanda Nunes has singlehandedly killed the most valuable women in the sport.
Brutally damaging to UFC.
Nunes isn't in the same marketing ballpark as either of those two.
— Darren Rovell (@darrenrovell) December 30, 2018
White responded to that strongly, calling Rovell's opinion some seriously dumb s**t and questioning what the f**k he knows about mixed martial arts. And seven months later he doesn't sound quite over the accusation that Nunes is bad for business.
"This guy likes f**king attention, okay?" White said at the post fight press conference. "This guy likes attention, and I'm going to give him more attention. You know, he says the worst thing that could have ever happened tonight was Amanda Nunes won. Not a star for the UFC. So, this is the kind of stupid s**t that we hear."
Never said Amanda Nunes wasn't a star for the sport. She is. She just isn't marketable and like Ronda, to some extent Holly and even Paige Van Zant, she isn't relevant outside the Octagon. There's no evidence proving otherwise pic.twitter.com/GFvXdNaizN
— Darren Rovell (@darrenrovell) July 7, 2019
And while White admits that Nunes is still in that period where she hasn't quite gained her footing as a bona fide superstar, he points to Chuck Liddell who was in the same spot until he iced Tito Ortiz.
"The numbers tonight were off the charts and she was part of that," White added. "It was a great card and a card that a lot of people were excited about. She's the co-main event. I tell you guys this all the time. I don't listen to this stupidness about anyone who says she isn't a star. They don't have any idea what they're talking about. I don't listen to that stuff."
For his part, Rovell responded to White's latest comments with a tweet that read "Never said Amanda Nunes wasn't a star for the sport. She is. She just isn't marketable and like Ronda, to some extent Holly and even Paige VanZant, she isn't relevant outside the Octagon. There's no evidence proving otherwise."
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EXCLUSIVE | Jon Fitch preparing to shock the world in Bellator 220 main event
Leon Edwards vs. Gunnar Nelson set for UFC London co-main event
Bellator 208 in Tweets: Pros react to Fedor's finish of Chael Sonnen
Share the joy The D'arce choke is a big player in the no gi realm. A close relative of

redpajama_set_name: RedPajamaCommonCrawl


text:
Sonoco Updates $115 Million Project Horizon Progress
Investment to Convert Hartsville, S.C., Corrugated Medium Machine to URB Scheduled to be Completed in Second Quarter of 2022
Company Announces Intentions to Close 70,000 Tons/Year of Capacity at Hartsville Mill Complex
HARTSVILLE, S.C., July 07, 2021 (GLOBE NEWSWIRE) -- Sonoco (NYSE: SON), one of the largest diversified global packaging companies, today provided a progress report on Project Horizon, its $115 million investment to transform its corrugated medium machine in Hartsville, S.C. to a state-of-the-art uncoated recycled paperboard operation with annual production capacity of 180,000 tons.
"The conversion of our corrugated medium machine (#10 machine) to URB is expected to be completed by the end of the second quarter of 2022, and there are a number of significant construction projects underway that will modernize the infrastructure of the entire Hartsville Mill Complex and allow for more efficient and safe handling of raw materials and finished goods," said Tim Davis, Division Vice President and General Manager, Paper & Adhesives, U.S./Canada.
A key element of Project Horizon is construction of a new stock prep system to provide approximately 650 tons per day of recycled fiber to the rebuilt #10 machine and other Hartsville cylinder machines. The new stock prep system will allow for increased consumption of lower-cost mixed paper, along with Old Corrugated Containers (OCC), and should be operational in October 2021, Davis said.
To reduce paper finishing and warehouse complexity and cost, Sonoco is also building a new offline winding operation and 102,000-square foot finished goods warehouse on the Hartsville complex. The new offline winding department will incorporate new state-of-the-art equipment and should create 16 new positions.
As previously announced, Sonoco will be exiting the corrugated medium market by early 2022 and expects URB capacity through its U.S. and Canada mill network to remain neutral at approximately 1.2 million tons. Based on the progress of Project Horizon, the Company now expects to permanently shut down its Hartsville #1 and #9 URB cylinder machines which will reduce annual capacity by approximately 70,000 tons. The exact timing of the closures will depend on market conditions as well as the start-up of the converted Hartsville #10 machine. In 2020, Sonoco permanently shut down a 30,000 tons/year machine in Hartsville and its 95,000 tons/year Trent Valley, Ontario, Canada paper mill.
The new Hartsville machine is being designed with the goal of being the lowest cost URB machine in the world, with the capability of producing a wide range of high-value paper grades to service Sonoco's industrial and consumer converted products businesses and external trade customers. Project Horizon is projected to drive $30 million in annual cost savings by 2023, ensure the long-term viability of the Hartsville paper mill complex and place its U.S. and Canada URB mill system into the top quartile of performance from a cost perspective, Davis said.
Sonoco is one of the world's leading producers of URB with the capability of producing approximately 2 million tons annually. The Company is also one of the largest URB producers in the U.S. and Canada operating 11 mills and 18 machines in South Carolina, Tennessee, Virginia, Massachusetts, Kansas, Wisconsin, California, Washington and Ontario, Canada.
Earnings Conference Call Webcast
Sonoco management will host a conference call and webcast to review its second quarter 2021 earnings and provide an update on Project Horizon beginning at 11 a.m. ET on Thursday, July 22, 2021. The live conference call and corresponding presentation can be accessed at www.sonoco.com, under the Investor Relations section, or at http://investor.sonoco.com.
Founded in 1899, Sonoco (NYSE: SON) is a global provider of consumer, industrial, healthcare and protective packaging. With annual net sales of approximately $5.2 billion, the Company has 19,000 employees working in approximately 300 operations in 34 countries, serving some of the world's best-known brands in some 85 nations. Sonoco is committed to creating sustainable products, services and programs for our customers, employees and communities that support our corporate purpose of Better Packaging. Better Life. The Company was listed as one of Fortune's World's Most Admired Companies for 2021 as well as being included in Barron's 100 Most Sustainable Companies for the third year in a row. For more information, visit www.sonoco.com.


text:
Q: React native: Scroll view refresh control pull to refresh not refreshing from top I have added pull to refresh inside web view using scroll view. It is working but the condition is that pull to refresh should only work when we are at the top of the page inside web view. Here is my code
<ScrollView
  contentContainerStyle={{flex: 1}}
  refreshControl={
    <RefreshControl
      refreshing={refreshing}
      onRefresh={onRefresh}
    />
  }
>
<WebView scalesPageToFit
    startInLoadingState
    ref = {webViewRef}
    originWhitelist={['*']}
    style={{ flex: 1 }} source={{ uri: url  }} onLoadStart={() => (setLoading(true))} onLoadEnd={() => (setLoading(false))}
    javaScriptEnabled={true}
    domStorageEnabled={true}
    setSupportMultipleWindows={false}
    />
    </ScrollView>

A: Added onScroll method for web view and got the yOffset and added condition based on that to reload the webpage/not
<WebView scalesPageToFit
startInLoadingState
ref = {webViewRef}
originWhitelist={['*']}
style={{ flex: 1 }} source={{ uri: url  }} onLoadStart={() => (setLoading(true))} onLoadEnd={() => (setLoading(false))}
javaScriptEnabled={true}
domStorageEnabled={true}
setSupportMultipleWindows={false}
onScroll={handleScroll}
/>

and the method
const handleScroll = (event) =>  {
console.log(Number(event.nativeEvent.contentOffset.y))
const yOffset = Number(event.nativeEvent.contentOffset.y)
if (yOffset === 0){
  console.log('top of the page')
  handleRefresh(true)
}else{
  handleRefresh(false)
}

}


The "WALKshop" promises a synergy between movement and writing. This combination fosters our ability to hear and to heed our inner voices. We will explore where we are coming from and where we are going – while landing in the place that we are.
Is it time for you to turn-off the outer noise of your life to discover or reconnect with your own inner voice?
Nature, movement, silence, discussions and writing with other women in a small group setting -- these are all tools to help you hear your most wise self and craft your life story and navigate your way.
We will walk and write... traveling from the Outer Space of our daily lives – arriving at the Inner Space of ourselves. Journey into the galaxy of your true nature where you can hear your clearest voice.
experience in writing. Participants will leave both grounded and uplifted.
FACILITATORS: Marijne van den Kieboom and Kate Lampel Link are co-founders of Leadership 'N Motion (L'NM). L'NM is an international movement that bridges walking and nature with mindfulness and personal leadership. Both Marijne and Kate walk regularly - and sometimes far – to make pilgrimages to their truest selves.


text:
Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice
Masaki Watanabe, Julie L. Boyer, Neil R. Hackett, Jianping Qiu, Ronald Crystal
Vascular endothelial growth factor (VEGF) produced by tumor cells plays a central role in stimulating angiogenesis required for solid tumor growth. VEGF-specific antibodies inhibit tumor cell line growth in animal models and a humanized monoclonal anti-VEGF antibody (bevacizumab [Avastin]) is approved as a treatment for metastatic cancer. We hypothesized that administration of an adenoviral (Ad) vector expressing the murine monoclonal antibody equivalent of bevacizumab would suppress human tumor growth in vivo. The Ad vector (AdαVEGF) encodes the light chain and heavy chain cDNAs of monoclonal antibody A.4.6.1, a murine antibody that specifically recognizes human VEGF with the same antigen-binding site as bevacizumab. AdαVEGF efficacy in vivo was evaluated with A-673 rhabdomyosarcoma and DU 145 prostate carcinoma cells in human tumor cell xenografts in SCID mice. For both tumor models, AdαVEGF directed the expression of high anti-human VEGF IgG antibody titers in vivo, the numbers of mitotic nuclei and blood vessels in the tumor were significantly decreased (p < 0.05), tumor growth was suppressed (p < 0.05), and there was increased survival (p < 0.005). Thus, AdαVEGF, encoding a murine monoclonal antibody that is the equivalent of bevacizumab, effectively suppresses the growth of human tumors, suggesting gene therapy as an alternative to bevacizumab monoclonal antibody therapy.
https://doi.org/10.1089/hum.2007.109
Published - 1 Mar 2008
Vascular Tissue Neoplasms
SCID Mice
Tumor Cell Line
Immunoglobulin G
Watanabe, M., Boyer, J. L., Hackett, N. R., Qiu, J., & Crystal, R. (2008). Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice. Human Gene Therapy, 19(3), 300-310. https://doi.org/10.1089/hum.2007.109
Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice. / Watanabe, Masaki; Boyer, Julie L.; Hackett, Neil R.; Qiu, Jianping; Crystal, Ronald.
In: Human Gene Therapy, Vol. 19, No. 3, 01.03.2008, p. 300-310.
Watanabe, M, Boyer, JL, Hackett, NR, Qiu, J & Crystal, R 2008, 'Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice', Human Gene Therapy, vol. 19, no. 3, pp. 300-310. https://doi.org/10.1089/hum.2007.109
Watanabe M, Boyer JL, Hackett NR, Qiu J, Crystal R. Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice. Human Gene Therapy. 2008 Mar 1;19(3):300-310. https://doi.org/10.1089/hum.2007.109
Watanabe, Masaki ; Boyer, Julie L. ; Hackett, Neil R. ; Qiu, Jianping ; Crystal, Ronald. / Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice. In: Human Gene Therapy. 2008 ; Vol. 19, No. 3. pp. 300-310.
@article{d58ef7e0e4ce499a88b8293c809327b8,
title = "Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice",
abstract = "Vascular endothelial growth factor (VEGF) produced by tumor cells plays a central role in stimulating angiogenesis required for solid tumor growth. VEGF-specific antibodies inhibit tumor cell line growth in animal models and a humanized monoclonal anti-VEGF antibody (bevacizumab [Avastin]) is approved as a treatment for metastatic cancer. We hypothesized that administration of an adenoviral (Ad) vector expressing the murine monoclonal antibody equivalent of bevacizumab would suppress human tumor growth in vivo. The Ad vector (AdαVEGF) encodes the light chain and heavy chain cDNAs of monoclonal antibody A.4.6.1, a murine antibody that specifically recognizes human VEGF with the same antigen-binding site as bevacizumab. AdαVEGF efficacy in vivo was evaluated with A-673 rhabdomyosarcoma and DU 145 prostate carcinoma cells in human tumor cell xenografts in SCID mice. For both tumor models, AdαVEGF directed the expression of high anti-human VEGF IgG antibody titers in vivo, the numbers of mitotic nuclei and blood vessels in the tumor were significantly decreased (p < 0.05), tumor growth was suppressed (p < 0.05), and there was increased survival (p < 0.005). Thus, AdαVEGF, encoding a murine monoclonal antibody that is the equivalent of bevacizumab, effectively suppresses the growth of human tumors, suggesting gene therapy as an alternative to bevacizumab monoclonal antibody therapy.",
author = "Masaki Watanabe and Boyer, {Julie L.} and Hackett, {Neil R.} and Jianping Qiu and Ronald Crystal",
doi = "10.1089/hum.2007.109",
journal = "Human Gene Therapy",
T1 - Genetic delivery of the murine equivalent of bevacizumab (Avastin), an anti-vascular endothelial growth factor monoclonal antibody, to suppress growth of human tumors in immunodeficient mice
AU - Watanabe, Masaki
AU - Boyer, Julie L.
AU - Hackett, Neil R.
AU - Qiu, Jianping
AU - Crystal, Ronald
N2 - Vascular endothelial growth factor (VEGF) produced by tumor cells plays a central role in stimulating angiogenesis required for solid tumor growth. VEGF-specific antibodies inhibit tumor cell line growth in animal models and a humanized monoclonal anti-VEGF antibody (bevacizumab [Avastin]) is approved as a treatment for metastatic cancer. We hypothesized that administration of an adenoviral (Ad) vector expressing the murine monoclonal antibody equivalent of bevacizumab would suppress human tumor growth in vivo. The Ad vector (AdαVEGF) encodes the light chain and heavy chain cDNAs of monoclonal antibody A.4.6.1, a murine antibody that specifically recognizes human VEGF with the same antigen-binding site as bevacizumab. AdαVEGF efficacy in vivo was evaluated with A-673 rhabdomyosarcoma and DU 145 prostate carcinoma cells in human tumor cell xenografts in SCID mice. For both tumor models, AdαVEGF directed the expression of high anti-human VEGF IgG antibody titers in vivo, the numbers of mitotic nuclei and blood vessels in the tumor were significantly decreased (p < 0.05), tumor growth was suppressed (p < 0.05), and there was increased survival (p < 0.005). Thus, AdαVEGF, encoding a murine monoclonal antibody that is the equivalent of bevacizumab, effectively suppresses the growth of human tumors, suggesting gene therapy as an alternative to bevacizumab monoclonal antibody therapy.
AB - Vascular endothelial growth factor (VEGF) produced by tumor cells plays a central role in stimulating angiogenesis required for solid tumor growth. VEGF-specific antibodies inhibit tumor cell line growth in animal models and a humanized monoclonal anti-VEGF antibody (bevacizumab [Avastin]) is approved as a treatment for metastatic cancer. We hypothesized that administration of an adenoviral (Ad) vector expressing the murine monoclonal antibody equivalent of bevacizumab would suppress human tumor growth in vivo. The Ad vector (AdαVEGF) encodes the light chain and heavy chain cDNAs of monoclonal antibody A.4.6.1, a murine antibody that specifically recognizes human VEGF with the same antigen-binding site as bevacizumab. AdαVEGF efficacy in vivo was evaluated with A-673 rhabdomyosarcoma and DU 145 prostate carcinoma cells in human tumor cell xenografts in SCID mice. For both tumor models, AdαVEGF directed the expression of high anti-human VEGF IgG antibody titers in vivo, the numbers of mitotic nuclei and blood vessels in the tumor were significantly decreased (p < 0.05), tumor growth was suppressed (p < 0.05), and there was increased survival (p < 0.005). Thus, AdαVEGF, encoding a murine monoclonal antibody that is the equivalent of bevacizumab, effectively suppresses the growth of human tumors, suggesting gene therapy as an alternative to bevacizumab monoclonal antibody therapy.
U2 - 10.1089/hum.2007.109
DO - 10.1089/hum.2007.109
JO - Human Gene Therapy
JF - Human Gene Therapy
10.1089/hum.2007.109


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University of Salford - Inclusive structures driving transformational change
Facilitated by Advance HE's 2021-22 Collaborative Development Fund Project, this case study is the University of Salford's contribution to the 'Inclusive institutions: enabling and supporting culture change' project.
Introductory blog
Interactive case study
Return to Inclusive Institutions homepage
The University of Salford project team explored cultural enablers that drive transformational change within our institution and our project has evidenced that a more inclusive culture grounded in a sense of belonging and value, leads to more impactful transformation when ingrained at the heart of large scale HE change projects. We highlighted ten enablers which are drawn from the strength and barrier themes that stem from the analysis of the research.
We learned that the sticky culture at the heart of the institution provides an inclusive environment for impactful transformation based on strong foundations and organisational cohesion. Factors for success were strongly related to how change feels; and through consideration of the lived experience and the understanding of pre-existing cultures, more effective communication and a more connected inclusive approach can be adopted to drive transformational change. Where this was present the outcome was more positive feelings about change across all levels of the organisation.
Our interactive case study captures key learning points enacted from transformational change that leans on and learns from pre-existing models. Success was found through tapping into shared motivations and personal drivers to craft an inclusive vision through the development of a culture of trust and belonging. We showcase our findings through a range of digital assets providing an evidence base for members seeking to explore and embed inclusive culture transformation.
In this introductory blog, Professor Jess Power gives an overview of the University of Salford project and shares her thoughts on inclusivity and belonging to drive institutional transformation within the higher education sector.
The key objectives of the project were threefold:
to examine how an institution can encourage a new culture to evolve
to investigate the differences in the facilitation of culture transformation between four diverse Academic Schools
to measure the impact in relation to benefits to staff in terms of wellbeing, a sense of belonging, value, and career development.
The University of Salford project findings are showcased through a range of digital assets providing an evidence base for members seeking to explore and embed inclusive culture transformation.
Download the outputs
Jess Power
Professor of Teaching and Learning
Jess is Professor of Teaching and Learning at The University of Salford and lead for the newly formed Learning and Teaching Enhancement Centre. She is a Principal Fellow of the Higher Education Academy, Fellow of The Textile Institute, Fellow of Chartered Management Institute, and a National Teaching Fellow.
Flexible Learning Facilitator
Matthew is the Flexible Learning Facilitator at the University of Salford working within the Learning and Teaching Enhancement Centre. He has worked in HE for 30 years and within the field of Learning Technologies for the last 15 years.
Davina Whitnall
Researcher Development Manager
Davina is Researcher Development Manager at the University of Salford and a freelance training consultant, writer and coach. She has worked in organisational development for over 20 years and in HE for over 13 years.
Eve Blezard
Eve is an early career researcher passionate about improving local communities' sustainability through combined research and practice. She has recently completed her thesis at Salford University entitled: 'Change, Loss, and Community: Residents' narratives of life on a social housing estate'.
Pouria Rafati
Pouria is a second-year PhD student in the field of Bionanotechnology. He is a Salford international excellence scholarship awardee and an early career researcher investigating novel methods of cancer therapy.
Andrea Stein
Andrea, from South Africa, is in the 3rd year of her PhD in Applied Psychology. She is a graduate member of the British Psychological Society (BPS) MBPsS.
Paul Broster
Associate Dean Academic (Student Experience)
Paul is Associate Dean Academic (Student Experience), School of Arts, Media and Creative Technology at the University of Salford. He is the School's lead for student experience, working with a range of stakeholders to ensure students engage in high quality programmes and are equipped for fulfilling careers.
John Dermo
Academic Developer
John is an Academic Developer in the Learning and Teaching Enhancement Centre at the University of Salford, linked to the School of Arts, Media and Creative Technology. He is joint Programme Leader for the PG Cert in Academic Practice and leads on academic professional development and talent recognition, supporting staff with HEA Fellowship applications and Teaching Excellence Awards claims.
Siân Etherington
Siân is an Academic Developer in the Learning and Teaching Enhancement Centre at the University of Salford, and consultant to the School of Health and Society. She is Co-chair of Salford Community for Excellence in Learning and Teaching and SCELT Pedagogic scholarship scheme and mentoring group, and joint Programme Leader for the PG Cert in Academic Practice.
Claire Hookham
Associate Dean Academic
Claire is the Associate Dean Academic (Quality and Enhancement) at Salford Business School. Claire has over 15 years' experience in Learning and Teaching within Higher Education, across three institutions.
Helen Keegan
Helen is Senior Lecturer in Interactive Media at The University of Salford. She is a Fellow of the Higher Education Academy and a National Teaching Fellow. She has a strong track record in curriculum and learning innovations, particularly focusing on technology-enhanced learning, open educational practices and emerging technologies.
Neil Withnell
Neil is Associate Dean Academic for the Student Experience in the School of Health & Society at the University of Salford. He has a passion for excellence in learning and teaching.


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Alzheimer's can be predicted early
February 24, 2015 | Sponsored | Turnstone Communications
Koen Dewaele (CEO) started ADx about three and a half years ago, when Fujirebio (the former Innogenetics), cut back its research activities drastically. Four employees who already worked on Alzheimer's biomarkers decided to continue the research and founded their own company. The company develops diagnostic tests to screen for Alzheimer's.
Alzheimer's is a dementia in which a person gets memory loss, has mood swings, becomes disoriented and loses the ability to make plans. About 100 years ago, the German psychiatrist and neuropathologist Alois Alzheimer described the disease for which he was later credited. The brain of a person with Alzheimer's exhibits abnormal structures such as "tangles" and "plaques". These structures are aggregations of proteins, in the case of plaques these are β – amyloids, and Tau in the case of tangles. Aberrant values of these proteins can be measured 5-10 years before a patient manifests the symptoms of Alzheimer's. By the time symptoms occur, it is too late to treat the disease adequately.
ADx has developed a test for measuring the proteins in cerebrospinal fluid that indicate an early stage of Alzheimer's disease. How does the test work exactly?
Koen Dewaele: "You need a good antibody to measure the toxic proteins. We inject peptides, based on tau, in mice. Their immune system produces antibodies against these peptides and we add an extra component to enhance this response. The lymphocytes are extracted from the spleen of the mouse and fused with a cancer cell line. In this way we get an immortal cell line that always makes the same antibodies. Next, we use these antibodies in an ELISA test system to determine the Tau quantitatively. If a certain amount (threshold) is exceeded, this indicates disease. "
Can you detect all patients who have Alzheimer's?
"Not all forms of dementia are due to Alzheimer's. There is also vascular dementia, and dementia due to accumulation of Lewy bodies, such as in Parkinson's. In some cases dementia occurs without an assignable cause. In 70% of cases, dementia is due to Alzheimer's disease pathology, i.e. aggregates of β-amyloids and Tau. We can detect those cases."
What is your marketing strategy?
"We are working with a German partner, Euroimmun, to produce our tests on an industrial scale and place them on the market. Our test is CE marked and is mainly used by the pharmaceutical industry. They are looking for objective criteria to screen patients that will develop Alzheimer's. Those patients can participate in clinical trials where new drugs are being developed for Alzheimer's. The test is also used by neurologists who want to make an early-stage diagnosis. This can, for example, be done by Prof. Dr Engelborghs in ZNA Middelheim or ZNA Hoge Beuken for 165 euros."
Research funds for Alzheimer's were cut in half.
"This is true, because the results of the studies for the development of drugs against Alzheimer's until now were not successful. This is largely due to the fact that 30% of the subjects with dementia don't show pathology of Alzheimer's disease, but were included in the clinical trials. This can be remedied with our diagnostic tests. The downsizing of the research funds is for us a setback as well as an opportunity, because people now start to realize the necessity of using biomarkers for diagnosis. Fortunately, ADx has its own funds. We currently have a number of investors, including Euroimmun, and we also received a number of grants. Most importantly, we want to do a capital increase before summer. We will welcome new selective shareholders, hopefully an industrial partner too."
What's in the pipeline?
"Currently we are able to determine whether someone has the pathology to develop Alzheimer's, but it is no indication when the symptoms will occur. It can take years. We are now working on a test to predict when symptoms will occur. We have seen that cognition declines when the synapses start to die. This can be evaluated by mapping the concentration of neurogranin. We see a clear correlation between the concentration of this protein and the functioning of the patients."
Suppose I run the test and I get diagnosed with Alzheimer's. As I understand it, there is no medication to help me?
"No, there is no medication that will really slow down the disease. That is why we are careful in communicating the existence of the test to patients. It is a heavy verdict and the clinician has no real treatment options."
What are your ambitions in the long term?
"We want to develop diagnostic tests for other neurodegenerative diseases such as Parkinson's and ALS. Also, we have the ambition to be able one day to biochemically diagnose depression and schizophrenia, as these are also diseases in which the biochemical processes in the synapses are disrupted. If we understand the pathology of these diseases, a more accurate diagnosis can be made and more specific medication could be developed. The brain is the least-known organ. Expect a big revolution over the next 50 years."
We would like to become a world-renowned company in neurodiagnostics for all neurodegenerative disorders, including schizophrenia, depression and Parkinson's.
The number of people with Alzheimer's disease or any other form of dementia has exploded. There are now about 47.5 million patients worldwide and The World Health Organization (WHO) predicts this number will be tripled by 2050, to 135.5 million people. Doctors, scientists and politicians debate the possibilities of enhanced international cooperation to curb the disease. Although dementia cannot yet be cured, patients should receive better emotional and physical support, says the WHO. In addition, the organization thinks the efforts to detect the disease in an early stage should be increased and wants to focus on a more targeted treatment of the physical suffering that accompanies dementia. Alzheimer's disease is the most common form of dementia by 60-70 percent.
Diagnostics Industry Neuroscience


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Maya Rudolph replaces 'polarizing' M&M's spokespeople
January 23, 2023 Charles Business 0
Transfer over, yellow, pink and inexperienced: Maya Rudolph is changing iconic M&M's "spokecandies" after the chocolate-covered sweet model inadvertently turned its inexperienced mascot's heels into "polarizing" sneakers final yr .
Pivot Comes Forward of Sweet's Feb. 12 Tremendous Bowl LVII Business and Takes Benefit The surprising culture war from early last year, That is when the story made its manner onto Fox Information, the place Opinion host Tucker Carlson criticizes M&M's mother or father firm Mars Inc. after replace Green's "sexy" shoes and rebranded its different colourful characters to be more inclusive and diverse,
Mars Wrigley Sweet, based in 1941, embraced the controversy with renewed vigor on Monday, turning the previous viral debate right into a strategically timed advertising and marketing alternative. Acknowledging that its overhaul had managed to "break the web", the corporate stated it had "determined to take an indefinite break from spokesperson." As an alternative it selected "a spokesman America may agree on" – "Expensive" Rudolph – to switch him.
photos of colourful mascots, who debuted in the 1960s and obtained the CGI therapy within the Nineteen Nineties, nonetheless seem on the narration, main many to consider that his "break". can't last very long And Monday's announcement could possibly be half of a bigger marketing campaign. And Spokesmen followers weren't completely satisfied.
"This has acquired to be a PR stunt. Please inform me it's," wrote one Instagram consumer within the feedback part of the announcement.
"Would you let Fox Information brag about horny sweet?" one other pair.
One other consumer wrote, "spokesman sweet is actually your model."
"Worst advertising and marketing choice ever," stated one other.
In the meantime, Rudolph will function the model's "Chief of Enjoyable" and "use his comedic abilities and personable persona to assist M&M's on its mission to create a world the place everybody feels included." They belong," the model stated in a press release.
Maya Rudolph in a behind-the-scenes picture from a manufacturing shoot for the 2023 M&M's advert marketing campaign.
(M&Ms)
The Emmy-winning "Saturday Evening Reside" alum, who will seem in an M&M's Tremendous Bowl advert, stated she is "thrilled" to be working with the corporate.
"I'm a lifelong lover of sweet and I really feel it's such an honor to be requested to be part of a marketing campaign for such a widely known model," stated the "Booty" and "Bridesmaids" star. today.com, "It is a fairly enjoyable pairing, if I do say so myself. I feel little Maya could be thrilled to be working with M&M's."
"I used to be already somebody who used to observe the Tremendous Bowl for commercials, so I am like, 'Wow, now I get to be part of that second!' He stated people,
Certainly, Rudolph isn't any stranger to the high-profile Tremendous Bowl industrial blitz. In 2021, she starred in Klarna's big-game debut as 4 quarter-sized singing cowboys to advertise the pay-in-installment service.
The comic has additionally served as a spokesperson for the Sling TV streaming service and common commercials for the green-products firm Seventh Era.
Hating Ticketmaster lengthy predates the Taylor Swift fiasco
Hiltzik: M&M's caveman pretend for conservative outrage marketing campaign


The fewer scheduled raisings are expected to alleviate traffic delays during the busier winter tourist season, which peaks at around Presidents' weekend.
In case of boating emergencies, the bridges may also be raised at any time, and by request of a US Government vessel.
Three bridges provide access on and off Anna Maria Island at Manatee Ave Highway 64, mid-island at Cortez Road, and at the southern point at Longboat Pass.
The Longboat Pass Bridge connecting Anna Maria Island to Longboat Key is raised for boats at any time on demand, all year.
Does anyone know about the large building that went by barge that passed under the Cortez bridge to Sarasota on October 19, 2008?
Sorry Marci, didn't hear anything about it. Perhaps someone can enlighten us.
It was a large barge going from Tampa and heading to Ft Lauderdale via the IntraCoastal Waterway. The barge was a glass structure for a show and to which other boats will tie up.
There is an International Boat Show there Oct 30 to Nov 3.
Hi! Does the drawbridge open? We are staying in Anna Maria and have a child with anaphylaxis to peanuts and treenuts. We need to be able to get across the bridge if necessary. Could you tell me if it opens and if so the times?
Yes, the drawbridge does open. As the article above says, the bridge goes up at quarter past and quarter to the hour, between 6 in the morning and 7 at night, but only if requested by boats requiring more than 17 feet clearance. Many boats can pass under the closed bridge. When the bridge goes up the car traffic is delayed about 5 minutes. In the event of an car accident or a mechanical or electrical failure, Cortez Bridge, a few minutes drive to the south, is an alternative route to the mainland.


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Tag Archives: Philip Baker Hall
Rod Lurie's The Contender
February 2, 2019 natewatchescoolmovies	Leave a comment
I like examining films about political corruption from decades ago that, if anything, were somewhat ahead of their time and are more potent these days in the age of the internet and social media. Rod Lurie's The Contender is no exception, and looks at abuse of power by those with a lot of it to wield, and the frequently used and very bratty tactic of bringing up events from people's past to run smear campaigns on the eve of elections, a dirty trick used heavily by both sides of any power struggle. Joan Allen is fantastic as a US Senator who is a strong candidate for Vice President until a fiery, amoral asshole of a rival played by Gary Oldman digs up dirt from her college days and threatens to derail the whole thing. This is a political drama and as such the script (courtesy of Lurie himself) has a whole truck of bells, whistles and supporting characters to give the film flourish, but at heart it's a fascinating moral dilemma revolving around Allen and Oldman. The attack on her is vicious, below the belt slander and although not unfounded, it's unwarranted by someone who is supposed to represent and uphold integrity with their position. The plot thickens when she discovers secrets of her own regarding his character and past, and struggles in herself whether to use this information to bring him down like he did to her, or rise above it and use other less sensationalist strategies to beat him. Her quandary culminates in a decision that many, including myself, would find fairly frustrating given the gauntlet of degradation she's forced to walk through as a result of Oldman's actions. That decision may not be what we want to happen emotionally as an audience based on what we've seen and felt, but it's easy to remove ourselves and see why she does this, and view the example she has set for peers by making the hardest of calls. It's mature, difficult storytelling and I'd forgotten what a thoughtful, prescient film this is. Many people from both sides of America's divided masses and political parties could learn a thing or two from this story. Allen never overplays the role and uses that quiet observance she's so good with to bring us closer to her character. Oldman is decked out in a strange curly wig and looks nothing like the sneering shark he becomes when he opens his mouth, it's an interesting visual character choice. Jeff Bridges plays the President (I'd vote for him IRL) and the cast is stocked with excellent talent including Sam Elliott, Christian Slater, Saul Rubinek, Philip Baker Hall, Mariel Hemingway, Kathryn Morris and William L. Petersen. Great film, and gets more important as each year passes.
Christian Slatercinemafilmfilm reviewfilm reviewsfilmsgary OldmanJeff Bridgesjoan allenMariel Hemingwaymoviemovie reviewmovie reviewsMoviesPhilip Baker HallRod LurieSam ElliottSaul RubinekThe Contender
Tom Clancy's The Sum Of All Fears
May 30, 2017 natewatchescoolmovies	Leave a comment
Surprisingly, The Sum Of All Fears is my favourite film version of Tom Clancy's Jack Ryan novels. Alec Baldwin did a bang up job in the superb Hunt For Red October,
Harrison Ford held his in two beyond excellent entries, and we won't speak of the Chris Pine/Keira Knightley snooze-palooza from a few years back. Why then do I gravitate towards this Ben Affleck incarnation? Who knows. Battfleck himself makes an adequate, inquisitive Ryan, on the younger end of the rope and under the guidance of CIA Yoda Morgan Freeman. I think it's the early 00's tone of the film itself though, the whip smart editing, Bourne-style escalation of suspense and terrific ensemble cast, a hallmark among Clancy films. Affleck embodies a younger, inexperienced Ryan whose infamous intuition is just breaching the surface of his character, right on time for a deadly plot to set off a nuclear device on American soil. A German radical (Alan Bates, underplaying evil nicely) with vague ties to a Neo Nazi faction is cooking up a false flag attack against Russia, using a long dormant warhead supplied by arch mercenary Colm Feore. Or at least I think that's the crux of it, these cloak and dagger affairs can get pretty dense on you sometimes. There's a sense of global danger though, a level of stress that ratchets up until even the stoic US President (an explosive James Cromwell) begins to lose it. The Russian President (Ciaran Hinds) gravely tries to sort out the misunderstanding, whilst Clancy staple character John Clark (Liev Schreiber gives Willem Dafoe a run for his money) covertly smokes out conspirators. Unease and tension nestle into the narrative, and when that impending disaster is minutes away during a hectic NFL game, you can feel the suspense in the air. The supporting cast is rich with talent including Michael Byrne, Bruce McGill, Philip Baker Hall, Josef Sommer, Ron Rifkin, Lisa Gay Hamilton and gorgeous Bridget Moynahan as Ryan's fiancé. I've got nothing but love for Red October, Patriot Hames and Clear & Present Danger, but something about this one hit a frequency and resonated with me a little better, coming out on top as the most re-watchable, enjoyable entry.
Alan BatesBen Affleckbridget moynahanbruce mcgillciaran hindscinemacolm feorefilmfilm reviewfilm reviewsfilmsJames CromwellLiev Schreibermichael byrneMorgan Freemanmoviemovie reviewmovie reviewsMoviesPhilip Baker Hallthe sum of all fearsTom Clancy
"I am very sure that's the man who shot me.": Zodiac 10 years later – by Josh Hains
March 5, 2017 Josh Hains	Leave a comment
The idea of offering up a defence for David Fincher's Zodiac seems rather silly given that ten years later it's widely regarded as perhaps Fincher's greatest film, often revered as one of the finer films released over the past decade. We all know it's great, though admittedly, I didn't know that for several years.
I avoided Zodiac like it was coated in radioactive slime until 2014. I had heard a great deal of positive things about the movie, and had been greatly intrigued by the marketing behind it, but the knowledge that not only was it was a long, slow paced movie, but also a rather unsettling one too kept me away for so long. When I did finally give it a chance late September 2014, my mind immediately gravitated toward Google, scouring through page after page of information about the investigation in an attempt to better understand the finer details of the case, and come to my own conclusions about who the Zodiac killer may have been. My gut however, felt like I'd eaten a bad take out meal, disturbed, shaken, and stupidly hungry for more. I felt like how I imagined Robert Graysmith felt all those years ago, minus the fear, paranoia, and impending danger of course.
That David Fincher populated Zodiac with such a great cast is a marking of a great director who knows how to compile actors who will treat the characters as individuals and not just caricatures. I find it intriguing and perhaps even ironic, or merely coincidental, that Jake Gyllenhaal starred in last year's underrated thriller Nocturnal Animals, given that in Zodiac he is essentially one. His Robert Graysmith is a nocturnal animal, an increasingly gaunt, wide eyed mouse sniffing around for a piece of cheese, in this case the next tangible clue or lead worth obsessively investigating. And it's all thanks to his unshakeable love for puzzles, a factor that helps decode the first Zodiac letter. As he digs deeper into the case, we come to fear for his safety, in particular during a genuinely white knuckling scene in which the unarmed and unimposing Graysmith ventures into the basement of someone we begin to assume might put an abrupt end to Graysmith's life.
Before the blockbuster splash that was Iron Man in 2008 thundered into the film scene, one could have argued that Robert Downey Jr.'s performance as the San Francisco Chronicle reporter Paul Avery was the best he'd ever given. An argument can be made that while he was seemingly born to play the billionaire tycoon and saviour of the planet Tony Stark, his best work still resides in the fractured Avery. The deeper the investigation gets the further Avery seems to slip from cool as a cucumber journalist to a paranoid, spineless slob.
Prior to his self induced exile on a houseboat, I got a kick out of the scene where he joins Graysmith (Jake Gyllenhaal) for drinks at a populated watering hole, chugging back those luminous bright blue Aqua Velvas while rambling about the case and their personal lives. There's a great sense of both humour and humanity in that scene, as Avery lets his guard down and actually engages with someone beyond a superficial relationship, while Graysmith sheds his mouse-like internalized mannerisms in favour of energetic, loud behaviour, though briefly. From this point forward however, Graysmith has a spine, albeit a rather loosely fitting one, and Avery has seemingly lost his, donning "I am not Paul Avery" buttons in the hopes of fending off potential threats. He'd have made a wonderful Doc Sportello.
And of course, there's San Francisco detective Dave Toschi played with a real sense of respectable authority by Mark Ruffalo. Toschi, an Animal Cracker snacking family man, and the inspiration behind both Steve McQueen's preferred method of wearing his service revolver in Bullitt, and Dirty Harry's iconic law breaking detective Harry Callahan, can't seem to figure out how to put the pieces together in the Zodiac case, understandable in light of the overwhelming amount of contradictory information at hand. Under Fincher's direction, Ruffalo portrays Toschi as a driven yet logically minded detective. He remains dedicated for years to catching the Zodiac, but lacks the desperation and paranoia Graysmith possesses. Instead, Toschi approaches every aspect of the case with the kind of logical thinking and reasoning every detective should be in possession of, following procedure by the book, and generally doing everything he can to crack the case until the psychological burden becomes far to heavy to bear. You can see how heavy sits in his mind by Ruffalo's subtle body language in later parts of the movie, and you soon feel sorry for the guy.
Near the end of the film, Graysmith declares "I need to stand there, I need to look him in the eye and I need to know that it's him.", desperate to prove that Arthur Leigh Allen (John Carroll Lynch; perfectly unnerving and subtle) is indeed the cold blooded killer. He gets his wish a short time later when he encounters Allen at an Ace Hardware store in Vallejo where Allen works as a clerk. Allen offers his assistance to Graysmith with a polite "Can I help you?", Graysmith responds with a "No.", the two men simply staring at one another until Graysmith leaves, Allen thrown off by Graysmith, and Graysmith appearing much more certain that Allens is the man they're after. The movie moves forward eight years to when Mike Mageau, survivor of the Zodiac killer at the start of the film, meets with authorities to potentially identify the Zodiac killer, positively identifying Arthur Leigh Allen as the man who shot him and killed Darlene Ferrin. While many had their suspicions and some evidence pointed in his direction, Allen died in 1992 before he could be questioned. Not that he would have confessed anyway.
Admittedly, I have intentionally left out many details and characters, with no disrespect intended, and it should be said that every actor involved in this film, from the leading performances to the smallest of cameos (for exmaple, Ione Skye of Say Anything as Kathleen Johns, a woman who was threatened in her car by the Zodiac killer), give world class performances, some even the best of their careers to date. And the script by James Vanderbilt, based on books by Robert Graysmith, is an achievement of impeccable research and respect for the case. And the cinematography by the late Harris Savides is bar none the greatest work the man had ever crafted, richly capturing everything with immaculate detail, from the lush valleys of California and its busy, inviting cities and streets, to the Aqua Vera drinks, to beams of red light emanating from police cars. He painted a gorgeous picture for us to gawk at for years to come.
Ten years later, I find it astonishing that Zodiac never truly ends like other movies do. Most movies tie up every loose thread with a ribbon to go with it, others leave room for potential sequels. You can't end a movie when their is no resolution in reality, forcing a tacked on Hollywood ending wouldn't sit right with anyone in possession of a brain. You can only leave the audience with the next best thing, the assurance of a living Zodiac victim that the man in the picture they're pointing to is indeed the man who shot him. That Fincher was bold enough to choose this manner of ending his film shows us he's a director capable of unsettling viewers long after the film ends, without needing to manipulate his audience or present alternative facts. Zodiac is a bona fide masterpiece, the crime film equivalent to All The President's Men, and just as good too.
All The President's MenAnthony AndrewsBrian Coxchloe sevignyCrimeDave ToschiDavid Fincherdermot mulroneyDonal logueElias Koteasfilmfilm reviewIone SkyeJake GyllenhaalJames Vanderbiltjimmi simpsonjohn carroll lynchJune Diane RaphaelMark RuffaloMoviesmysteryNon FictionPaul AveryPhilip Baker HallRobert Downey Jr.Robert GraysmithSuspenseThrillerZodiac


Every year, Medical Environment Update  acquires a detailed report of OSHA citations by standard for medical (the category includes clinics, ambulatory surgery centers, and various outpatient settings) and dental practices from the OSHA Office of Management Systems. Here is an excerpt from that report.
For more more details, see the the post on the September Medical Environment Update .


Beyond fostering transparency, we believe that careful, honest reporting facilitates savvier decision-making in all areas of life. When a trusted news organization delivers reliable news and insight, it gives its users tools they need to make decisions more effectively.
Seventy-seven years ago, in the midst of a horrendous world war, the leaders of the Reuters news agency made a fateful decision: They would publicly commit Reuters to independence and neutrality and resist any government's attempt to commandeer or unduly influence their journalists.
This decision, reaffirmed when Reuters went public in 1984 and again when Reuters was purchased by the Thomson Corporation to form Thomson Reuters in 2008, governs the role of Reuters in the world today. Committed via our culture and our corporate charter to "integrity, independence and freedom from bias," we endeavor not to take sides but rather to provide news, data and information upon which individuals, businesses and governments can rely. Our Trust Principles remind us to put our own political views aside when we write and edit, and to provide facts and insights with professional dispassion.
This means we keep an open mind when gathering facts. We seek fair comment. When we make mistakes, which we do occasionally, we correct them quickly and fully. When we hear rumors, we track them down and report them only when we are confident that they are factual. We value speed but not haste: When something needs more verification, we take the time to check it. We try to avoid "permanent exclusives" – first but wrong.
In a world in which distrust of media – and of many institutions – is rampant, we believe our approach builds and inspires trust. The transparency it fosters is essential to holding government officials to account. And it makes markets of all kinds run most efficiently. At Reuters, we contribute to the proper functioning of these markets by rapidly delivering accurate information to all participants everywhere in the world. If news affects markets, we are all over it.
Increasingly, we offer transparency about our own processes, as well. Earlier this year, we began including a link to the Thomson Reuters Trust Principles at the bottom of all stories on Reuters.com to make these rules more readily apparent to our readers. In addition, from time to time, when we think it might be useful to the reader, we provide an explanation – which we call Backstory – of how we have reported a particular piece. These additions reflect a commitment not only to deliver accurate, unbiased news but to share more information about the way we work and the standards under which we operate.
Beyond fostering transparency, we believe that careful, honest reporting facilitates savvier decision-making in all areas of life. A news user may be trading or investing or doing deals or practicing law – or just deciding whether to buy a house or what policies and politicians to support. When a trusted news organization delivers reliable news and insight, it gives its users tools they need to make decisions more effectively.
We can't solve every problem in the journalism world, and we know there are many such problems – including the rapid-fire proliferation of blatantly untrue or highly biased stories through social media. We support responsible efforts to identify and discredit such stories, while continuing to support a robust, free, uncensored press.
But the best way for any news provider to combat untrustworthy news is to produce trustworthy news – and nothing but. And that remains our commitment, 167 years into the Reuters journey.


text:
Stanbic IBTC Rewards More Nigerians with Cash Prizes At Monthly Draws
Stanbic IBTC Bank, a subsidiary of Stanbic IBTC Holdings, has rewarded more customers in its ongoing Reward4Saving Promo Season 2, with 70 Nigerians from different regions winning ₦100,000 each in its monthly draws, which held recently in Lagos State.
The Reward4Saving promo is a nationwide campaign aimed at rewarding customers with cash prizes monthly and the second season aims to give out ₦156 million to almost 900 Nigerians within a 12-month period. The goal of the campaign is to encourage and promote a healthy savings culture among Nigerians and is open to new and existing customers who save a minimum amount of ₦10,000 monthly.
Speaking at the August live draw where various 70 individuals were rewarded, Omiyi Eromosele, Head, Consumer Client Coverage, Stanbic IBTC Bank, stated that customers who qualify to participate in the monthly draws, also stand a chance of winning ₦1 million in the quarterly draws.
On his part, Emmanuel Aihevba, Head, Main Markets Clients, Stanbic IBTC Bank noted that the promo is the bank's way of giving back and empowering its loyal customers. He said, "to deliver on our promise to continually reward our customers for their loyalty, we have created this platform which will run till March 2023, and have so far given away ₦42 million to deserving savers".
Emmanuel further encouraged customers to continue to top up their savings accounts in multiples of ₦10,000 monthly to increase their chances of winning, while prospective customers should download the Stanbic IBTC Super App, visit the web portal or any Stanbic IBTC bank branch or @ease banking agent to open an account, or an e-wallet and start saving immediately.
Sanwo-Olu attends Queen Elizabeth Commemoration Service
GOV AKEREDOLU RECEIVES GOVS FAYEMI, MAKINDE, OTHERS ON CONDOLENCE VISIT •Says Late Lady Evangelist Akeredolu Was A Great Mother


text:
<?php

namespace AcmePhp\Ssl\Exception;

/**
 * @author Jérémy Derussé <jeremy@derusse.com>
 */
class CSRSigningException extends SigningException
{
}

redpajama_set_name: RedPajamaGithub


text:
the literate lens
photography, writing and the spaces between
Damaged Goods: An Interview with Larry C. Price
Where did the gold for your wedding ring come from, and what was involved in its production? How about those fancy running shoes, or the surprisingly cheap silk shirt you bought your sister for her birthday? What about the 70% cacao chocolate you like to nibble after dinner?
These kinds of questions have been nagging at photojournalist Larry C. Price for many years. But it wasn't until last year that he had a chance to pursue them. In August 2012, Price, who'd been working as the photo editor of the Dayton Daily News, resigned in protest from his job when he was asked to lay off half his staff. With time on his hands, the way forward was clear: he would go back to his roots.
Since graduating from college, Price has been doing hard-hitting photojournalism, either as a staff photographer for newspapers or on his own time. His back catalog isn't too shabby: he won the 1981 Pulitzer Prize for spot news photography, for coverage of the 1980 coup in Liberia, and a second Pulitzer for feature photography in 1985, for a portfolio documenting civil wars in Angola and El Salvador. He's a former National Geographic photographer and one of an elite group of Olympus Visionaries (which is how I met him).
But now, what he really wanted to focus on was child labor. Ever since the 1980s, when he'd photographed child soldiers working in Nicaraguan sugar cane fields, Price had wanted to photograph child workers more extensively. In an age of globalization and cheap consumer goods, illuminating this issue seemed more important than ever. Many of the cheap goods we enjoy are made, quite literally, on the backs of child workers–and Price thought it was time to show people that.
His work harks back to a time a hundred years ago, when Lewis Hine exposed the blight of child labor in the United States. Working for the National Child Labor Commission, Hine spent over a decade going undercover to coal mines, cotton mills, canneries and glass factories. His heartbreaking images of child workers were instrumental in getting new child labor laws passed, and Price—who plans to make this a long-term project—is working in the same vein. Like Hine, he says, "I have a point of view, and I'm not making any excuses for that."
So far, Price has photographed child laborers at gold mines in the Phillippines and Burkina Faso; he plans to broaden the project to other industries and other countries soon. Last week, he spoke to The Literate Lens from his home near Dayton, Ohio.
Literate Lens: First of all, what's it like to be out in the field again?
Larry Price: I love it! I've slipped back into it pretty easily. In my life, I've gone back and forth between editing and shooting more times than I can count. Shooting is my preference, it's wonderful to be able to do creative work. I feel there's a mission here that I'm really at peace with, and there seems to be some interest in it.
LL: Why child labor?
LP: I feel that the public's general awareness of this problem hasn't kept up with the way it's swelled through globalization. Some of the numbers are staggering: in western Africa there are 200,000 child workers in the mining sector alone. I felt that now was a really critical time to talk about these issues, so that people can understand and try to make informed decisions about where they get their goods and services.
LL: How did you get started, research-wise?
LP: At first, I was just doing research on the Internet. Typically, I start with a broad idea. You develop notions and see where they lead—it unfolds over period of months. Going to gold mines was actually a spinoff of another idea I had, to do a project on environmental lead poisoning in children. I started researching that, and I got friendly with some NGOs doing work in that field. They suggested things for me to read. I read academic reports from various sectors, and there were long bibliographies at the end, so I could find people who'd done fieldwork in these areas. I've talked to people from Scotland, Scandinavia, Africa, all over. Research has become easier now because I've met these people.
LL: Very few photographers are doing work on child labor these days, compared, say, to war reporting. Why do you think that is?
LP: I think the reason is that it's just really hard. Access is frustrating, you have to be careful and street smart, and you're dealing with people who probably don't want you doing what you're doing. Working in the Phillippines was difficult for me at times. For each of the six locations I went to, I had to have meetings with local officials just to get to the areas. Once I was there, there was a lot of suspicion. I just had to operate as best I could.
LL: Did you ever have any tense situations?
LP: A couple, yes. One day in the Phillippines, I was photographing some independent miners who'd been digging pits, with permission, near a large mining operation. The second day I was there, the large corporation brought in a bunch of guards, made everyone leave, and bulldozed the mines the men had been digging for months. They were building an access road; those mines were in the way. It was clear they didn't want me there, but I had permission from the governor of the province, so I schmoozed my way through. Of course I didn't say I was doing a project on child labor; I just told them I was doing a project on small-scale gold mining. You have to be judicious about what you say.
LL: With that in mind, how do you present yourself to the workers and children you're photographing? Do they get what you're doing?
LP: The children are easy because they're curious. It's a break in their routine: a photographer shows up and it's a big curiosity. I'd have a troupe of kids around me for a while, then they'd get shooed off by parents, who were worried the kids were bothering me and also wanted them to get back to work. It's just a matter of patience. I'd study the children carefully and would try to convey certain activities. Then I'd work with a child or two, following their routines. The parents picked up on the fact that I was photographing children more than adults, but I tried to concentrate and didn't get into long explanations.
LL: How much does it affect you emotionally when you see children in those situations?
LP: It does affect me, for sure. In the Phillipines it wasn't so bad, because as hard as the kids were working, it seemed like they had plenty to eat and parents around, and I didn't see tragic situations. Burkina Faso was a bit more desperate. Some kids were running around naked in the hot sun all day long, working hard, and they looked a bit undernourished. The thing that really disturbed me was thinking about them working underground in unsafe conditions. They also work around machines that are pulverizing ore into a flour-like powder, and they sit at the base of these machines, surrounded by torrents of dust and powdered quartz. They're not using any protection. You can hear this constant refrain of low coughs, and I just know these kids are developing lung ailments and not getting medical treatment. I read about it and then I witnessed it, and that got to me.
LL: You wrote eloquently about these stories for the Philadelphia Inquirer and the Pulitzer Center on Crisis Reporting. What kind of non-visual documentation do you do when you're there?
LP: I've got one those 3×5, 150-page Moleskines in my cargo pocket, and I start a new one each trip. Everything goes down in there: date, time, location, GPS coordinate if possible. On this project, I feel I can do 90 percent visually, but it's always important to have the scope and texture of narrative to guide viewers along the visual path. I've done everything from 1,000-plus word articles to short blog posts and Facebook updates. It was fun to try to post some updates in real time while I was there; I think there's tons of potential for doing real time journalism like that. At the end of the day I'm a visual journalist, but the operative word is journalist: I'm trying to tell a story.
LL: You're also doing advocacy through this work, right?
LP: Definitely. I have a point of view, and I'm not making any excuses for that. I'm trying to do this project on a larger, long-term scale; I've got several stories in mind. I want to show kids working, but I also want to show the impact of child labor all over the world. There's a lot of work to do. Right now I'm working in this little sector of gold mining, but there's human trafficking, the garment industry, fishing… it goes on. I'm thankful I'm in good shape, I have stamina and I can do it.
LL: A lot of people who look at these images will ask, What can I do to remedy this? So, what can they do?
LP: I think the best long-term answer is to try to become an educated consumer. If you're buying a diamond, there's a big movement in the diamond industry to have conflict-free diamonds–which is a step in the right direction, but it can also be a bit of a bogus marketing thing. As far as gold goes, I don't think people should feel guilty about buying it, especially as a lot of gold is recycled. But they can be aware and put pressure on governments and communities to make laws and enforce laws. What can you do? Just be educated. Understand, reach into your conscience. You might not be able to stop kids working if the families are in desperate economic need. But you can give the parents representation, and try to make sure that the kids spend at least part of the day in school. Governments all have their priorities—but not too many governments on the planet really want four-year-old kids working twelve hours a day in the hot sun. I really believe that.
Visit Larry C. Price's web site.
Read the article Price wrote for the Philadelphia Inquirer.
Read Price's article about coal mining in the Phillipines at the Pulitzer Center on Crisis Reporting.
Read Price's article about coal mining in Burkina Faso at the Pulitzer Center on Crisis Reporting.
Donate to The Child Labor Coalition.
Find out about socially-responsible investing here and here.
8 comments on "Damaged Goods: An Interview with Larry C. Price"
rnewman504
It's very hard to look at these photos, especially as the mother of a six-year old. I hope Price's photographs bring not only awareness but real change. Great article, Sarah!
sarahjcoleman
Thanks for this, Robin. It has been interesting for me to study Lewis Hine and see that, in his case, slowly chipping away at the problem for many years did lead to real social change. Of course these days we have information overload and compassion fatigue and all that, but I'm hopeful that if great photographers like Larry can continue to do this work, it will eventually have an effect!
Nick Kelsh
Wow. Larry is the real deal. This is such fabulous important work. Heartbreaking photographs.
Indeed, Nick! Hope your photography is going well.
Peter Tobia
"Damaged Goods" is visual reporting that captivates the viewer and demand attention. "Gold" and "children" are precious words that may work beautifully in the line of a poem, but Larry Price's pictures and words tell a different reality much closer to the truth.
Jim Meldrum
This shows why we should be thankful for what we've got.
Absolutely, Jim! Wish I could make my own kids understand this!
Steve Ducharme
One of the few issues in politics that can be universally condemned regardless of your left/right position and something that breaks my heart as the father of a 12 year old daughter. Great series. I hope it gains a LOT of traction.
This entry was posted on May 23, 2013 by sarahjcoleman in Interviews, Uncategorized and tagged Burkina Faso, child labor, globalization, gold mining, Larry C. Price, Phillippines.
https://wp.me/p25Qfq-t0
Sad news and a new book
Past Due: An Interview with Kerry Mansfield
Life in the Face of Death: A Tour with Nancy Borowick
How the New York Times puts words and images together
Inside-Out: An interview with Manjari Sharma and Irina Rozovsky
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Frankly, I do not know. May be I was searching for something on the internet and this cover picture came in the forefront, helping me make a decision spontaneously to pay a visit here. As I mentioned earlier, having the possibility to reach a destination as fast as possible is the single most important reason for me to make a decision, if I am not taking leave from work. So, weekends matter. I did some research and found that I can take a flight on Saturday night from Pune to Ahmedabad, take a late night train from Ahmedabad to Palitana (210 Kms), reach Palitana temple town in the morning, visit the temples & nearby market during the day, take return train in late evening and catch early morning flight from Ahmedabad to Pune, join office on Monday morning. Too hectic schedule to be followed but it was worth it. When the schedule seems possible, I do everything to make it a reality. As one devotee in my train to Palitana pointed out, HE has called me and HE will take care of me ...... (follow the instructions below for accessing the rest of this article).


InTone is a great tool to be used alone or in conjunction with surgery depending on each patient's need!
After prescribing InTone Maribelle Verdiales, M.D., customizes the settings for InTone and the patient is shown how to use it at home. A sensor in the unit measures the strength of the patient's contraction while visual biofeedback is provided to further encourage the patient's performance. The hand-held control unit uses voice-guided instruction to guide the patient through the exercise routine, reminding her to maintain relaxation of her abdomen, buttocks and leg muscles. Each daily session takes about ten minutes, and data from each session is recorded.
After two weeks, the patient follows up with Maribelle Verdiales, M.D., who will analyze her recorded data and modifies InTone settings based upon the patient's progress. Patients will continue to follow up once per month for a duration of 14-26 weeks, based upon her diagnosis.
To contact Maribelle Verdiales, M.D., please call (770) 266-0935.


text:
Military-Ready: Building a More Diverse & Inclusive Workforce
June 7, 2021 / By FourBlock
Listen and Subscribe
"When you have diverse candidates from varying backgrounds, that brings diversity of thought, and that diversity of thought spurs innovation. In order to continue to thrive as an organization, you need to be innovative."
A U.S. Air Force Veteran with more than 20 years of military recruiting experience, Launia Terry, M.S., SHRM-SCP, has devoted her career both during and after military service to human resources, with a focus on diversity and inclusion. This week, Launia joins hosts Lindsey Pollak and Mike Abrams on the FourBlock Podcast to share some of the challenges she faced in her own transition and provide expert insights and actionable advice for organizations who want to take steps to go from being "military-friendly" to truly "military-ready" for veterans in their workforce. Launia discusses why diversity and inclusion in the workplace is so important and offers guidance for those interested in pursuing career pathways in the diversity and inclusion field.
As for why she continues to give back to the veteran community despite her busy schedule, Launia says, "I had such a difficult time with my transition, that if I can help one veteran to have a much smoother transition...I feel like I'm making a huge impact."
In addition to serving as FourBlock's Diversity and Inclusion Leader as well as a Career Readiness Instructor for the Philadelphia Career Readiness Program, Launia is the Director of Corporate Talent Acquisition for Day & Zimmermann, a century-old, family-owned company specializing in construction & engineering, operations & maintenance, staffing, security and defense for leading corporations and governments around the world.
Launia joined Day & Zimmermann in September 2016 and has held several progressive roles. In her current position, she leads the talent acquisition function by providing strategic insight into the full lifecycle of recruiting staff employees, diversity recruiting initiatives, and relationship building between hiring managers, HR business partners, and candidates.
Launia has a bachelor's degree in Human Resources Management from Park University and a master's degree in Human Resources Development from Villanova University. A recently retired U.S. Air Force Veteran, Launia has more than 20 years of recruiting experience.
Welcome to the FourBlock Podcast, a show that examines veteran career transition and the military-civilian divide in the workplace. General Charles Krulak coined the term "Three Block War" to describe the nature of 21st-century military service defined by peace-keeping, humanitarian aid, and full combat. But what happens next? Veterans are often unprepared to return home and begin new careers. We call this the Fourth Block.
FourBlock is a national non-profit that has supported thousands of transitioning service members across the nation in beginning new and meaningful careers.
Mike Abrams (@fourblock) is an Afghanistan veteran, FourBlock founder, and author of two military transition books. He'll be representing the military transition perspective. Lindsey Pollak (@lindsaypollak) is a career and workplace expert and New York Times bestselling author of three career advice books. Lindsey will be representing the civilian perspective of this issue.
Veterans, explore new industries and make the right connections. Find a career that fits your calling. Join us at fourblock.org. Sponsor our program or host a class to equip more of our veterans at fourblock.org/donate.


text:
class Octave < Formula
  desc "High-level interpreted language for numerical computing"
  homepage "https://www.gnu.org/software/octave/index.html"
  url "https://ftp.gnu.org/gnu/octave/octave-5.2.0.tar.xz"
  mirror "https://ftpmirror.gnu.org/octave/octave-5.2.0.tar.xz"
  sha256 "2757b5cc1854c9326d6c99d2900c7cec2909ac7ed500212d170d0df592bfd26b"
  license "GPL-3.0"
  revision 9

  livecheck do
    url :stable
  end

  bottle do
    sha256 "5c9af6d3f0f61cd764067c1f66997b0044788dc76e8ddc28c6f64194a275d09c" => :catalina
    sha256 "37389123fb6ec5bda0ef8874596231b6e22a20d60ce9cb792a97c18bff7f307f" => :mojave
    sha256 "e44de6cb9315e2f125ea516733513c048b38fd9c77719eb270717daff43360a6" => :high_sierra
  end

  head do
    url "https://hg.savannah.gnu.org/hgweb/octave", branch: "default", using: :hg

    depends_on "autoconf" => :build
    depends_on "automake" => :build
    depends_on "bison" => :build
    depends_on "icoutils" => :build
    depends_on "librsvg" => :build
  end

  # Complete list of dependencies at https://wiki.octave.org/Building
  depends_on "gnu-sed" => :build # https://lists.gnu.org/archive/html/octave-maintainers/2016-09/msg00193.html
  depends_on "openjdk" => :build
  depends_on "pkg-config" => :build
  depends_on "arpack"
  depends_on "epstool"
  depends_on "fftw"
  depends_on "fig2dev"
  depends_on "fltk"
  depends_on "fontconfig"
  depends_on "freetype"
  depends_on "gcc" # for gfortran
  depends_on "ghostscript"
  depends_on "gl2ps"
  depends_on "glpk"
  depends_on "gnuplot"
  depends_on "graphicsmagick"
  depends_on "hdf5"
  depends_on "libsndfile"
  depends_on "libtool"
  depends_on "openblas"
  depends_on "pcre"
  depends_on "portaudio"
  depends_on "pstoedit"
  depends_on "qhull"
  depends_on "qrupdate"
  depends_on "qt"
  depends_on "readline"
  depends_on "suite-sparse"
  depends_on "sundials"
  depends_on "texinfo"

  uses_from_macos "curl"

  # Dependencies use Fortran, leading to spurious messages about GCC
  cxxstdlib_check :skip

  # Octave fails to build due to error with java. See also
  # https://github.com/Homebrew/homebrew-core/issues/39848
  # Patch submitted upstream at: https://savannah.gnu.org/patch/index.php?9806
  patch do
    url "https://raw.githubusercontent.com/Homebrew/formula-patches/a8124b73c5216cc81d63627a4b41203ab1d91a4d/octave/5.1.0-java-version.patch"
    sha256 "7ea1e9b410a759fa136d153fb8482ecfc3425a39bfe71c1e71b3ff0f7d9a0b54"
  end

  def install
    system "./configure", "--prefix=#{prefix}",
                          "--disable-dependency-tracking",
                          "--disable-silent-rules",
                          "--enable-link-all-dependencies",
                          "--enable-shared",
                          "--disable-static",
                          "--with-hdf5-includedir=#{Formula["hdf5"].opt_include}",
                          "--with-hdf5-libdir=#{Formula["hdf5"].opt_lib}",
                          "--with-java-homedir=#{Formula["openjdk"].opt_prefix}",
                          "--with-x=no",
                          "--with-blas=-L#{Formula["openblas"].opt_lib} -lopenblas",
                          "--with-portaudio",
                          "--with-sndfile"
    system "make", "all"

    # Avoid revision bumps whenever fftw's, gcc's or OpenBLAS' Cellar paths change
    inreplace "src/mkoctfile.cc" do |s|
      s.gsub! Formula["fftw"].prefix.realpath, Formula["fftw"].opt_prefix
      s.gsub! Formula["gcc"].prefix.realpath, Formula["gcc"].opt_prefix
    end

    # Make sure that Octave uses the modern texinfo at run time
    rcfile = buildpath/"scripts/startup/site-rcfile"
    rcfile.append_lines "makeinfo_program(\"#{Formula["texinfo"].opt_bin}/makeinfo\");"

    system "make", "install"
  end

  test do
    system bin/"octave", "--eval", "(22/7 - pi)/pi"
    # This is supposed to crash octave if there is a problem with BLAS
    system bin/"octave", "--eval", "single ([1+i 2+i 3+i]) * single ([ 4+i ; 5+i ; 6+i])"
  end
end


text:
Helmi Järviluoma
Helmi Järviluoma is a sound, music, and cultural scholar and Professor of Cultural Studies, University of Eastern Finland. Her main research interest has been soundscape studies, especially sonic remembering. Decades of research on this topic have culminated in the publication of Acoustic Environments in Change (2009) which sums up her four consecutive interdisciplinary, international soundscape research projects studying the changing European soundscapes. Currently, her research focuses on the theme of dis-placement, mobilities, aging, memory and technology. Among her 170 publications, Gender and Qualitative Methods (2003/2010) continues to draw positive attention. Throughout her career she has been a promoter of scholarly communities, includingThe International Association for the Study of Popular Music (IASPM), latest as General Secretary (2009-2011), and the Nordic Researching Music Censorship Network (2008-2015). After having different leadership roles in the Finnish Society for Ethnomusicology for 17 years, she has been among founders of several new associations, including Finnish Society for Cultural Studies (Vice Chair and Chair 2008-2011). She is a member of the committees of three international journals, including Ambiances, and Popular Music. She has written and directed altogether five radio features for Finnish Broadcasting Company, two alone, two in co-operation with Steven Feld, and one with Noora Vikman.
Research Keywords: ethnography, memory, music, sound
Popular Music and Ageing
ACT Members
Co-applicants
Affiliated students
Postdoctoral researchers


text:
From a release
Niagara Icewine Festival
January 13 to 29 2023
Find Out More & Buy Tickets Here
With thousands of acres of snow-covered vines to set the scene, the annual Niagara lcewine Festival offers three weekends of incredible wine and culinary events. From the opulent Niagara lcewine Gala to street festivals and winery events, there is something for every taste and style.
The Niagara Icewine Festival is part of the Niagara Grape & Wine Festival and takes place January 13th through 29th across Niagara.
This year's Niagara Icewine Festival includes a weekend Discovery Pass self-guided touring program, the Cool as Ice immersive experience on January 14th and the Niagara-on-the-Lake Icewine Festival on January 20th, 21st, 22nd, 28th and 29th.
The Niagara Grape and Wine Festival is celebrating its 73rd year.
Niagara Icewine Festival and Niagara Parks team up to offer all-new Cool as Ice immersive one-night event at Niagara Parks Power Station on January 14, 2023;
Peller Estates Winery & Restaurant and the Riverbend Inn & Vineyards are offering fireside experiences January 13 to 15;
All-inclusive event tickets offer admission to one of Niagara Falls' most exciting new attractions, incredible wines, cocktails and foods, live entertainment, dancing and event parking.
On each of the festival weekends, historic Queen Street in Niagara-on-the-Lake becomes the Icewine Village. It's a food and wine lover's paradise, where you can stroll and sample the best of local wineries, and pairings with the area's finest restaurants.
Image courtesy of Niagara Parks Power Station
Cool As Ice
Niagara Icewine Festival will host the annual Ice Wine Event, Cool as Ice, at Niagara Parks' newest must-see attraction, the Niagara Parks Power Station. This January, wine and food lovers will be wowed with an all-new feast for the senses. Cool as Ice is an immersive celebration showcasing Ontario's signature flavours through VQA Icewines, cocktails and mocktails, and farm-to-table fare, set within Niagara Falls' most buzzed-about new attraction, the Niagara Parks Power Station.
kets to January 14th's Cool as Ice event offer an all-inclusive evening featuring a diverse selection of Icewine, cocktail and mocktail tastings, hyper-local culinary stations showcasing the exquisite delights prepared by Niagara Parks' culinary team, access to the Niagara Parks Power Station's full experience, and event parking.
In addition to unparalleled views of Niagara Falls, Cool as Ice will also feature live performance art and stunning photo backdrops set to a music soundtrack sure to inspire time on the event's dance floor.
Cool as Ice Immersive Event at a Glance
Date: January 14 / Time: 7 pm – 11 pm
Location: Niagara Parks Power Station, 7005 Niagara Parkway, Niagara Falls
Dress Code: Wine Country Creative (Guests are encouraged to showcase their signature style, whether that's gala-style glamour or wine-country chic)
Pricing: $225 per person
Niagara Grape & Wine Executive Director, Dorian Anderson, is quoted in a media statement.
"After having to press pause on Icewine festivities for a few years, we wanted to come back in a huge way for 2023 with a jaw-dropping new venue. The Niagara Power Station really lends itself to the type of creative expression and exploration that Icewine is all about. Our guests won't just get to explore Icewine and local foods in unique and unexpected ways, hosting Cool as Ice at the Niagara Power Station will allow our guests to explore and enjoy Niagara Falls in incredible new ways as well."
The Icewine Village in 2020:
culinary festival Niagara travel niagara winery travel ontario