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THE CANADIAN PRESS/Ryan Remiorz
World Juniors: Canada shuts down Finland to advance to the gold medal game
By Brandi Awad
By Agnes Wong
By Cara Gilhula
Team Canada is headed to the World Junior finals after a 5-0 shutout victory over Finland during the World Junior semi-finals in Ostrava on Saturday.
Canada opened with three goals in the first four minutes of the game. Connor McMichael found the back of the net at 1:48, followed by Alexis Lafreniere (3:05) and Jamie Drysdale (3:55).
"Guys, let's just get things started, shall we?" – @con91mcmichael, probably. pic.twitter.com/j6ITqbNT5z
— #WorldJuniors (@HC_WJC) January 4, 2020
Ty Dellandrea landed the fourth goal in the first period at 14:49. Fired up for the next period, Team Canada pushed to hold their lead, and Lafreniere managed to score his second of the game at 17:53 to increase their lead.
Alexis Lafrenière with big #2020Vision energy.pic.twitter.com/syT9anm1Wi
The World Junior finals will take place on Sunday. Canada will face Russia for the gold medal. This will be a rematch of the preliminary round where Russia handed Team Canada their only loss of the tournament (6-0).
NOT ON BAHLER'S WATCH 🛑pic.twitter.com/y8Foq0v9I9
Game 5: Canada 6-1 Slovakia
In the first period, captain Barrett Hayton got Canada on the board with a goal from Alexis Lafrenière. This is Lafrenière's first game back after missing the previous two games due to a knee injury.
READ: Top 10 moments at the World Juniors for Team Canada
There it is! Alexis Lafrenière, in his return from injury, finds the captain Barrett Hayton to get 🇨🇦 on the board first 👀 pic.twitter.com/wioLrYNBd9
— TSN (@TSN_Sports) January 2, 2020
Canada continued to add onto its lead in the second, with goals from Connor McMichael, Jacob Bernard-Docker, Liam Foudy, and Lafrenière.
Guess who's back? Alexis Lafrenière 👀👀👀 pic.twitter.com/yyCRhjFU0d
In the final frame, Hayton scored a power play goal early into the third, extending Canada's lead. Six minutes and 10 seconds into the period, Oliver Okuliar got the Slovaks got onto the board.
How about another power-play goal for Barrett Hayton? 😱 second of the day for the captain pic.twitter.com/aoKkIJLfdo
Hayton was awarded Player of the Game.
Canada will face defending champions Finland on Saturday at 1 p.m. ET.
Game 4: Canada 7 – 2 Germany
Team Canada took to the ice for their fourth game of the 2020 IIHF World Juniors Championships with a healthy 7-2 victory over the Czech Republic.
Canada got off to a solid start on Tuesday afternoon against the host team, Czech Republic. Forward Joe Veleno opened the scoring for Canada, sinking a bouncing puck just 4 minutes and 41 seconds into the game. Nolan Foote made it 2-0 just before the 10 minute mark with a slap shot from the point for a second power play goal. Barrett Hayton made it 3-0 for Canada at 13:29 with the third power play goal of the game.
READ: Canada's World Junior stars: Where are they now?
Nolan Foote's preferred mode of transportation: 🚀pic.twitter.com/q0FbrHVCDn
— #WorldJuniors (@HC_WJC) December 31, 2019
Continuing to increase the lead for Team Canada, Connor McMichael found a loose puck off a scramble and sent it to the back of the net for a 4-0 lead heading out of the first period. The Canadians tied a tournament record with four power play goals in a single period.
Halfway into the second period of play, brought an stressful minute for Canadian fans with four goals scored within 80 seconds, two goals apiece. Vojtech Strondala broke hopes of a Canadian shutout, putting up a point for the Czech Republic. 14 seconds later Libor Zabransky scored a second goal for the Czech Republic making it 4-2.
Team Canada's Liam Foundy responded with a quick bounce back just ten seconds later to make it 5-2. Goal six for Canada came less than a minute later by Dylan Cozens for the fifth and final power play goal of the game. Team Canada ended the second period with a 6-2 lead over the Czech Republic.
The @HC_WJC train keeps rolling here in Ostrava. Jared McIsaac nabs his 1st of the tournament off a pass from @Dylan_Cozens and 🇨🇦 now leads 7-2 #WorldJuniors pic.twitter.com/GQUPsQpaNT
— IIHF (@IIHFHockey) December 31, 2019
Halfway into the third, Canada's Jared McIsaac navigated his way through traffic to increase the Canadian lead to 7-2 and capture his first goal of the tournament.
With this win, Team Canada finishes at the top of Group B standings. They'll face Slovakia in one quarter-finals in Ostrava. As for the Czechs, they finish in fourth place and will face top-seed Sweden from Group A.
Rising star Alexis Lafreniere remains out with a knee injury.
Team Canada hit the ice at the 2020 IIHF World Juniors on Monday, where they bounced back from their Saturday loss to Russia with a 4-1 victory over Team Germany.
Nolan Foote opened the scoring for Canada, after capitalizing on a rebound from Kevin Bahl to score his second goal of the tournament.
NOTHIN' BUT NET for @foote_nolan 🙌 #WorldJuniors pic.twitter.com/yEmcvk2gXa
Team Canada carried this momentum into the second period, where they put up two more goals thanks to Liam Foudy and Calen Addison. While two German defenders got caught up with Ty Dellandrea, he was able to pass the puck to Foudy, who sniped a perfect, uncontested shot past German netminder Hendrik Kane to up Canada's lead.
Just a couple of minutes later, Addison scored on a 5-on-3 powerplay to secure a dominant 3-0 lead for the team.
Absolute 🚀 from @calenaddison ! 3-0 🇨🇦 @hc_wjc #WorldJuniors pic.twitter.com/Jh6JaAK1Xa
With less than two minutes to go in the third, Canada took two costly penalties, allowing Germany's Yannik Valenti to cut into their lead by 1. Following their goal, they pulled Kane from the net in hopes of catching up, but Canada's Ty Dellandrea scored his second empty-netter of the tournament to finish off the game at 4-1.
Joel Hofer made his goaltending debut for the Canadians, where he recorded 22 saves in their victory.
This win has moved Team Canada back to the top of the Group B standings ahead of their final round robin game tomorrow. They'll be taking on tournament-host Czech Republic in New Years Eve showdown at 1:00 PM ET.
Game 2: Canada 0 – 6 Russia
Team Canada falls to Russia in game two of the 2020 IIHF World Juniors
Canadians around the country felt sorrow as Team Canada suffered a tough loss to Russia in their second game of the World Junior championships in Ostrava, Czech Republic on Saturday.
2⃣ great chances but no 🎲 for @hc_wjc on this play.
3 🇷🇺 0 🇨🇦 after 20.#WorldJuniors pic.twitter.com/XKYqnqF3lU
Russia opened up the scoring early in the game with a goal from Alexander Khovanov just 1 minute and 44 seconds into first period play. The Russians continued with two more goals in the first period from Pavel Dorofeyev and Nikita Rtishev.
With the Canadians trailing 3-0 heading into the second period, forward Alexis Lafreniere needed to be helped off the ice after an apparent knee injury. The arena was dead silent as he was attended to by teammates and training staff. The potential No. 1 pick in next summer's 2020 NHL draft, Lafreniere looked in significant pain after catching his leg in the pads of Russian goaltender Amir Miftakhov and did not return to play.
Alexis Lafrenière goes down after a scary collision with the Russian goaltender. pic.twitter.com/S5hLEHdk9P
— TSN (@TSN_Sports) December 28, 2019
Last year's bronze medallists kept putting on the pressure.
A minute after play resumed, Nikita Alexandrov of Russia made it 4-0 with a close-in deke. Team Canada replaced goaltender Nico Daws, with Joel Hofer. Russia put back two more goals with a tip in from Yegor Sokolov and a shot from the slot from Grigori Denisenko.
After the second period, Russia sat 6-0. No goals were scored in the final period.
Next up, Canada will take on Germany on Monday, December 30 at 9 am ET.
Game 1: Canada 6 – 4 United States
Team Canada kicked off their 2020 IIHF World Juniors campaign with a win over rival USA on the first day of the tournament in Ostrava, Czech Republic. It didn't come easy, but the Canadians were able to top the Americans 6-4 in a wild Boxing Day match up.
Alexis Lafreniere, the NHL's projected No. 1 pick at the 2020 Draft, had a huge game for Canada, scoring one goal and three assists – including the game winner.
The game started off slow for the Canadians, who trailed 2-0 in the first period after the US' Shane Pinto and Arthur Kaliyev scored a pair of goals on the power play. Despite not meeting the back of the net, Canada wasn't ready to let that shake them.
🚨 That celly tho. 🚨@con91mcmichael gets @hockeycanada on the board! #WorldJuniors pic.twitter.com/zHHpdvwWTY
In the second period, the Canadian squad came out ready to play and put up three unanswered goals.
Canada's first goal of the tournament came from Connor McMichael on a centering pass from Akil Thomas to make the game 1-2.
Captain Barrett Hayton scored next, slapping one past US goaltender Spencer Knight on the power play to tie the game. Shortly after, the game was turned in Canada's favour by Nolan Foote who also scored on the power play to give them a 3-2 advantage heading into the third.
Ty Smith ➡ @foote_nolan = @HockeyCanada taking the lead! #WorldJuniors pic.twitter.com/jU635WIudY
In the final period, things got a little tricky.
While Canada took an early 4-2 lead with another goal from Hayton, the US was quick to respond this time. Nick Roberston scored his first of the tournament to edge the American's a little closer. Then, Shane Pinto scored his second power play goal of the night to even out the game.
Suddenly, Canada's lead was in jeopardy.
However, just seven seconds after Pinto's goal, Lafreniere buried one in the net to restore Canada's lead again with just minutes left in the game.
ALEXIS. LAFRENIERE. What else is there to say?! pic.twitter.com/tVyObK4fZw
Ty Dellandrea sealed the win with an empty-netter. This marks Canada's first victory over the USA since the 2015 World Juniors.
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DRMC and the Victorian Opera, in collaboration with Melbourne University Faculty of Music, offered a participatory music education program with professional musicians to primary school aged children from Boronia P.S., Tecoma P.S., Ferny Creek P.S., Silvan P.S., St Josephs Catholic P.S. and Mountain District Christian School. This was a repeat of the successful 2010 project. The program consisted of two parts - an incursion into schools with 2 x 60 minute, interactive workshops, one with singers and the other with instrumentalists and an excursion to Victorian Opera's Horti Hall for children to experience an extract of the opera Hansel and Gretel by Englebert Humperdinck.
The singing workshops were held at each primary school and involved VO's Developing Artists (DAPs): Emily Uhlirch (soprano), Maxine Montgomery (soprano), Matthew Thomas (bass baritone), Daniel Todd (tenor) and Daniel Carter (accompanist) presented by Richard Gill and Angus Grant. This workshop introduced students to material from The Marriage of Figaro by Mozart, La Boheme by Puccini, La Traviata by Verdi and Manon by Massenet, as well as, different voice types, language, text, story, characts and drama involved in these operas.
The instrumental workshops involved students from Melbourne University Faculty of Music: Nick Waters (Violin 1), Beatrix Stewart (violin 2), Christine Cheng (viola) and Jonathan Chim (cello) Jasper Ly (oboe), Tamara Kohler (flute), Jana Mollison (clarinet) and Chris Martin (bassoon). Each soloist demonstrated the range and sound of their instrument in a short 30 second display. The string quartet performed an extract from the String Quartet by Haydn, String Quartet in G minor Op. 10 by Debussy and the Wind Quartet performed Wind Quartet No. 1 by Francaix.
The Horti Hall excursion involved 2 sessions with 3 schools attending each. The Developing Artists and Melbourne University Instrumentalists performed an extract from Hansel and Gretel and Angus Grant worked with students discovering more about opera, costumes, props, chorus singing and further developing the drama.
Richard Gill led the project, mentoring the Vic Opera's DAPs, students from Melbourne Uni and Angus Grant from Vic Opera in music education processes that promoted participation and engagement.


Agility Forex is the smarter way to move your money around the world or between different currency accounts at the same bank. Based in Vancouver, Canada, we've introduced a simpler, faster way to transfer your funds with the best exchange rates and zero commission or hidden charges, no matter the size of the transaction. Agility Forex removes the wide spreads, fees and commissions, making it easy to send money abroad or between your different currency accounts at the same bank at the lowest possible cost. Our proprietary technology allows us to access the interbank market directly and our service is online so can be accessed anywhere and anytime in the world. Canadian-owned and operated, and governed by the laws of Canada, we specialize in all-things Canadian Dollar and aim to provide the best service and best pricing on all Loonie cross rates.


This was one of the cakes that leapt out at me when first perusing Dan Lepard's Short & Sweet and I was keen to make it as soon as possible – which I did back in October and have left it so long that Dom has beaten me to it. AND his looks brilliant!!! I've not come across cakes made with coconut milk very often and found it quite intriguing. I was hoping to include it as one of the Open House cakes, but in the end it just wasn't feasible, either the original or a cupcake version I had been toying with. So, having bought the necessary ingredients, I made a version of it the following weekend for us anyway. It's not strictly a chocolate cake, but I was planning to incorporate chocolate somehow as well as use up some odds and sods left over from the big bake.
Placed 50g desiccated coconut in a small bowl.
Warmed 160ml coconut milk up in a pan.
Poured this over the coconut.
Added 1 tsp vanilla extract and 50ml white rum, then covered the bowl and left for a couple of hours.
Creamed 250g unsalted butter with 300g cardamom sugar (caster) until light and fluffy.
Beat in 4 smallish hens eggs, alternating with a little of the flour.
Added 275g twice sifted flour (100g wholemeal, 175g white), 2 tsp baking powder and 1/4 tsp bicarb of soda alternately with the coconut mixture.
Divided between two 22 cm round cake moulds and baked for 30 mins at 180C.
Squeezed half an orange over the two cakes whilst hot (it was meant to be lime and rum, but I didn't have any lime and forgot the rum).
Left to cool for 10 minutes then turned out onto racks to cool completely.
Found a small dish of buttercream icing lurking in the fridge.
Beat this up with 150g mascarpone and one of my jars of apple & lemon curd.
I'd also meant to add 100g melted white chocolate, but I forgot!
Sandwiched the cakes together with the apple/lemon mascarpone then spread the rest over the top and around the sides.
Topped with 40g white chocolate shavings.
Despite some of the ingredients I forgot, they couldn't have been essential, because this turned out to be a really lovely cake. When asked his thoughts, CT helpfully stated "it tastes like a homemade cake". What he actually meant by that, was it tasted like a real cake made by a real person and was utterly delicious. It was not overpoweringly coconutty, but the rum came through clearly and pleasantly. It was moist and had a good firm chewy texture. The apple cream, mascarpone filling and icing complemented it well and was delicious in its own right. For some reason, it reminded me of a really good banana cake – but without the banana!
You've got me laughing now. I love the way you seem to just bundle everything together ("I forgot this", "I didn't have that") but it always turns out fantasic. This cake looks great. I gave my copy of Dan's book to sister – its time I got it back.
This looks absolutely fabulous Choclette and I am a sucker for coconut in cakes! Love CT's review too and rum in cakes also get my vote!
SUCH a pretty cake and your photos are lovely.
This looks delicious and very homemade 🙂 Just got a copy of short and sweet on loan, cant wait to read through it later.
Laura – Glad to hear you've got your copy now – now what, I wonder are you going to make first?
Karen – thank you. I really like the slightly chewy texture that coconut brings and thank you for saying such nice things too.
Baking Addict – now that's good thinking. What do you reckon?
I like the idea of using coconut milk in the cake. My mum used to make a nice coconut cake and this reminds me of it.
Definitely one to make me salivate!
oh it looks lovely, I love the way you've covered yours in white chocolate… I think people thought mine was too and they were quite shocked to find out it was slivers of coconut instead!… and at least e get to see inside yours too!… great thing about this post is that I know exactly how good it tastes… wee hee!
It looks gorgeous, and the cake looks really moist and light. I love the way you've decorated it with white chocolate – really elegant!
I would love this cake, but the rest of the tribe aren't big coconut fans. It looks absolutely splendid, Choc!
I've been eyeing up this cake in Short & Sweet for a while…your version looks delicious. Love how you've managed to sneak some chocolate in there too – you can hardly tell the difference between white chocolate shavings and coconut!
you had me at "coconut"! Looks divine!
This cake looks soooooo good. I could just eat a slice right now!
Corina – yes, it was the coconut milk that appealed to me.
Scott – excellent. If I don't make someone salivate, I've failed!
Celia – you'll just have to come over and have a slice with me then.
CC – thank you. I have penchant for coconut too.
MCB – you'd be very welcome – assuming I had a slice left!
Coconut is one of my most favourite things to bake with, glad there is also a use for the tinned stuff too in it!
The cake looks really tasty, glad it worked out so well with your alterations!
Johanna – he he, things are coming to a pretty pass indeed when I forget chocolate!
This looks like a delicious cake and I especially like the addition of using coconut milk to soften the dessicated coconut.
Maggie – thank you. That is what appealed to me.
I always have coconut milk in the house but I never thought to use it for softening dried coconut – I bet that makes for a moister cake – I like this idea! The cake sounds lovely.


Pioneer experts say strong plant genetics paired with BMR gene offer premium silage.
Growers now have access to a brown midrib trait in elite genetics from Pioneer Hi-Bred, a DuPont business, providing hybrids with increased fiber digestibility for dairy cattle. The company is releasing Pioneer hybrid P1376XR, a 113-day BMR hybrid, in limited quantities to growers primarily across the northeastern United States for the 2012 planting season.
"Through the industry-leading silage genetics research program, Pioneer plant scientists discovered a BMR gene in elite Pioneer germplasm," says Kyle Whitaker, Pioneer senior sales and marketing manager - global forages. "The new Pioneer BMR hybrid is unlike any BMR on the market today because of its outstanding agronomic performance. P1376XR combines the digestibility you expect from a BMR with tremendous yields, high starch, strong drought tolerance, and a robust disease and pest package."
This hybrid contains Herculex XTRA insect protection for above- and below-ground protection, as well as the Roundup Ready Corn 2 trait and the LibertyLink gene.
Historically, growers who would plant BMR hybrids had to choose digestibility over tonnage, standability and overall plant health. Pioneer hybrid P1376XR possesses the strong agronomics package you expect from an elite Pioneer hybrid, staying healthy and standing in the field through harvest without sacrificing yield, compared to competitive BMR hybrids.
"New P1376XR helps growers capture the value of increased fiber digestibility without giving up tonnage," says Bill Mahanna, Pioneer dairy nutritionist. "Through testing, we know that increased fiber digestibility will lead to improved intakes and increased milk production. All these factors contribute to greater profitability on the farm."
For 2012 and 2013, Pioneer will offer one BMR hybrid, with plans for additional BMR hybrids by the 2014 planting season.
"Pioneer is excited to offer a BMR product, helping growers match the right product to their specific needs," Whitaker says. "Pioneer's nutritional sciences team is committed to helping growers increase production efficiency and whole-herd profitability and improving forage quality - whether that's with Pioneer brand inoculant 11C33 with a BMR hybrid, or conventional silage hybrids paired with our fiber technology inoculant, 11CFT."
For more information on Pioneer brand BMR hybrids and crop-specific inoculants, visit www.pioneer.com/BMR or see your local sales professional.


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Q: Bootstrap columns not responsive in webpage I am currently trying to have my display look like this where my top portion has 3 images equally distanced and at the bottom there are 2 images like below

I tried using Bootstrap by having the top 3 images as
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This is my current code:

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A: *

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A: Try Something Like This
Please do not use fixed size when you want your layout be responsive. In container5 css class you used width: 300px;.
Here is your Live link Click here

redpajama_set_name: RedPajamaStackExchange


David from Remodeling R Us came to our home to give us a free estimate for a kitchen remodeling. He was very professional and knowledgable and was able to create a layout for us on his computer which was very helpful. They created the kitchen of my dreams and they kept my home very clean and organized through out the project. I am very happy with the end result and I would recommend them to all my friends.
Did entire bathroom remodel with demo. Excellent communication and honest hard work.
They were very professional. They were here everyday until completion. I am very pleased with the results!


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A team of 200 priests comment on daily Gospel
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March 18th: St. Cyril of Jerusalem, bishop and doctor of the Church
Gospel text (Jn 15,1-8): Jesus said: «(…) You are already made clean by the word I have spoken to you; live in me as I live in you. The branch cannot bear fruit by itself but has to remain part of the vine; so neither can you if you don't remain in me. I am the vine and you are the branches. As long as you remain in me and I in you, you bear much fruit (…)».
St. Cyril of Jerusalem, bishop and doctor of the Church (313-386)
EDITORIAL TEAM evangeli.net (based on texts by Benedict XVI) (Città del Vaticano, Vatican)
Today our attention is focused on St Cyril of Jerusalem. His life is woven of two dimensions: on the one hand, pastoral care, and on the other, his involvement, in spite of himself, in the heated controversies that were then tormenting the Church of the East.
Cyril was exiled three times within the course of approximately 20 years: the first time was in 357, after being deposed by a Synod of Jerusalem; followed by a second exile in 360, instigated by Acacius; and finally, in 367, by a third exile —his longest, which lasted 11 years— by the philo-Arian Emperor Valens. It was only in 378, after the Emperor's death, that Cyril could definitively resume possession of his See and restore unity and peace to his faithful. Of Cyril's writings, 24 famous catecheses have been preserved, which he delivered as Bishop in about 350. Taken as a whole, Cyril's homilies form a systematic catechesis on the Christian's rebirth through Baptism.
—He tells the catechumen: «You have been caught in the nets of the Church (cf. Mt 13: 47). Be taken alive, therefore; do not escape for it is Jesus who is fishing for you, not in order to kill you but to resurrect you after death».
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We had such an amazing time at our annual barbecue beach party this year at Montrose Beach. There was great food and great Sangria; the nice open field to toss a football around was another plus. Thanks to everyone who came out and thank you for bearing with us with the event-date change. The great weather that came was well worth the wait! Below are some captured moments. Please upload your pictures to our Facebook album if you took any as well!
Our social directors, Yen and Norm.
Yen and Norm for prepping the food.
Yen and Patty for grilling and making sure that everyone was well-fed!
Shelley, Tina, Autumn, Craig, Frank, Shannon, who helped set up and clean up.
Finally, to TJCCC, who co-hosted the event with us.
See you at our next barbecue in about 365 days!
Post in Recap, Social | permalink.


On March 27, 2019, Utah Governor Gary Herbert signed HB 57, a bill designed to increase privacy protections by requiring law enforcement to obtain a search warrant before being able to access a person's data held by electronic communication or remote computing service providers, including location information.
Just last year, in Carpenter v United States, 138 S.Ct. 2206 (2018), the Supreme Court declared a Fourth Amendment privacy right for cell phone location data. The Court revised its long-held "reasonable expectation of privacy" test and ruled that law enforcement obtaining cell site location information records from a person's cell phone service provider constitutes a search under the Fourth Amendment and requires a warrant.
Notably, this law expressly carves out an exception for "subscriber records," defined as "a record or information of a provider of an electronic communication service or remote computing service that reveals the subscriber's or customer's: (a) name; (b) address; (c) local and long distance telephone connection record, or record of session time and duration; (d) length of service, including the start date; (e) type of service used; (f) telephone number, instrument number, or other subscriber or customer number or identification, including a temporarily assigned network address; and (g) means and source of payment for the service, including a credit card or bank account number." By exempting such subscriber records from the warrant requirement, the Utah law tracks the familiar set of non-content records that can be obtained through a 2703(c)(2) subpoena under the federal Stored Communications Act (SCA), 18 U.S.C. §§ 2701 et seq.
Finally, the new Utah law requires that law enforcement agencies notify the owner of electronic information or data in question, or of the electronic device, once they have executed a search warrant to access that information. This must be completed within 14 days after law enforcement obtains the information pursuant to the warrant. Later, law enforcement must destroy the information in an unrecoverable manner as soon as reasonably possible after it was collected.
Utah's new law will no doubt impact how electronic communications and remote computer service providers handle law enforcement requests for electronic evidence – especially as other states follow Utah's lead – and could well lead to litigation over how such state law requirements operate alongside the federal SCA. In this evolving legal landscape, providers of telecommunications, digital messaging, and other electronic communications or remote computing services should reexamine how they handle law enforcement requests for electronic evidence. Providers facing an uptick in electronic evidence requests may also want to consider sharing specific guidelines through the ISP List used by law enforcement agencies for sending requests.


text:
John C. Onoda
Maurer School of Law Academy of Law Alumni Fellows (2010)
About John C. Onoda
John C. Onoda has spent most of his career in the public relations profession, counseling the world's most visible and influential companies during a period of unprecedented change. After earning his law degree, Onoda earned a master's degree from the Medill School of Journalism at Northwestern University. He spent the next five years as a newspaper reporter and in 1981 began a distinguished public relations career as a senior communications executive with several Fortune 500 companies. In 2002 he joined Fleishman-Hillard International Communications, where he advises companies on reputation management and corporate social responsibility. Onoda has also provided communications counsel and managerial expertise to several nonprofit organizations. He served for many years on the board of trustees of the Arthur Page Society, the country's leading organization for corporate communications officers, and in 1997 was inducted into the Medill School of Journalism's Hall of Achievement.


text:
The mechanism of formation of volatile hydrides by tetrahydroborate (III) derivatization: a mass spectrometric study performed with deuterium labeled reagents
Resolve DOI: https://doi.org/10.1016/j.sab.2005.03.015
Search for: D'Ulivo, A.; Search for: Mester, Z.; Search for: Sturgeon, R.
April 30 4
423–438; # of pages: 16
Hydride formation; Mechanism; Deuterium–hydrogen exchange; Mass-spectrometry
In order to clarify the mechanism of hydride formation, the isotopic composition of arsine, stibine, bismuthine, germane, stannane and hydrogen selenide formed by derivatization with either NaBD4 (TDB) or NaBH4 (THB) with inorganic As(III), Sb(III), Bi(III), Ge(IV), Sn(IV) and Se(IV) in aqueous reaction media and under various reaction conditions was determined. Batch hydride generation and gas chromatography–mass spectrometry (GC–MS) were employed. The analyte, present in 0.5–5 ml of acid solution (0.1–10 M in HCl or HNO3 or HClO4) was derivatized with 1 ml of 0.25–0.5 M TDB / THB in 0.1 M NaOH solution. For TDB derivatization in H2O reaction media, almost pure BiD3 and SbD3 were always obtained for Bi(III) and Sb(III). Nearly pure AsD3 could be obtained only under some reaction conditions. In general, for As(III), the isotopic composition of the arsines depends strongly on reaction conditions and included all possible AsHnD3−n from almost pure AsD3 to almost pure AsH3. For Ge(IV) and Sn(IV), the isotopic composition of generated GeHnD4−n and SnHnD4−n depends on reaction conditions, but pure GeD4 and SnD4 could never be obtained. Pure H2Se was obtained in all cases, independent of reaction conditions. The occurrence of side reactions involving D–H exchange in TBD during its hydrolysis and before the derivatization step, as well as on recently formed hydrides following derivatization was investigated. D–H exchange in TDB during acid hydrolysis appears to occur to a limited extent. Amongst the hydrides, H2Se undergoes H–D exchange whereas germane and stannane do not exchange at all. Arsine undergoes D–H exchange at elevated acidities (pH < 0) whereas stibine and bismuthine do not exchange significantly during the generation and stripping steps. A reaction model for hydride generation is proposed accounting for primary reactions giving rise to hydride formation through reaction intermediates, as well as side reactions involving D–H exchange and decomposition of reactive hydroboron species, reaction intermediates and final products. Hydrides are formed by direct hydrogen transfer from boron to the analyte atom, most likely through concerted mechanisms taking place via reaction intermediates.
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Winnipeg police will not lay charges in a fatal stabbing earlier this month.
Elmer Kakewash, 29, was stabbed in the upper body on June 4 in the 200 block of Dufferin Avenue.
Police say an altercation ensued with a group of people, resulting in Kakewash being stabbed. He later died in hospital from his injuries.
Police identified a suspect on June 10 and arrested a man. However, after consulting senior crown attorney, charges against him will not be laid.
The case is now considered closed. No further details were released.


If you consider installing natural stone flooring over underfloor heating you should know the benefits: slips-resistance (reduced risk of accidents due to slipping) and an increased lifetime (with proper maintenance) compared to other materials. You have the following steps: preparation, installation, applying adhesive, cutting tiles, sealing and grouting joints.
How to install natural stone flooring over underfloor heating?
If the original underlay is from wood, you will need a proper support for tiles. Install it according to manufacturer requirements, for assuring a clean underlay, dry and solid, suitable for the traffic supported by surface tile.
For wooden underlay, a preliminary phase is needed such as building a solid layer for laying the heating pipes, then cladding it with natural stone.
Over solid underlay, you can start installing the heating pipes, according to manufacturer's recommendation. Usually, the floor is cladded with a thermo insulating material (example: extruded polystyrene) over which pipes are fixed with straps or systems provided by the manufacturer of heating system. Also, install a band from thermo insulating material over room's perimeter, for preventing the thermal bridge between heated floor and walls. For building the underlay, a screed with special additives for underfloor heating is poured, with thickness specified by installation manufacturer.
After finishing this step, natural stone tiles can be fixed with a suitable adhesive and 10 mm maximum thickness.
General rule is to work from center to the side. Measure length and width of your space and draw a cross in the middle. From this cross, start installing dry tiles with suitable joints (minimum 3 cm), for allowing smooth circulation while using underfloor heating. When using different size joints, grout is variable and the degree of variation can be controlled before starting the installation procedure. When installing tiles with variable thickness, the thickest tile should be install first, because it is the reference for flooring level. Make sure you do not have difficult cuts that require adjustments.
Always make sure you have a perfect look flooring, when entering the room. Because natural stone tiles are slightly different, put aside tiles you are not using in the center, for later installation around edges.
For reducing tile displacement, which can lead to cracking and/or detachment, leave a small area around corners, minimum 6 cm width. This space will be filled with suitable grout. Flexible like silicone, for allowing tiles displacement (if you have floor plinth, this space should be left free).
Install the tiles with a flexible adhesive, enhanced with polymers, such as Weber Set Porcelain. Adhesive color to be used depends on tile color and used grout; for example, when installing natural stone tiles with color variation close to cream, use white adhesive, based on white cement to prevent development of grey stains over the tile surface. Add adhesive in clean water and mix according to instructions, until obtaining an even consistency.
Use a grooved trowel with teeth, keeping it at an angle of 45° when applying the adhesive in the installation area. Practically, you need to develop parallel ribs, which will act as underlay for tiles. These ribs are shaped with a steady twisted movement, for levelling the ribs of adhesive and producing a steady 3 – 4 cm adhesive bed underneath tiles.
It is recommended to work on small areas and remove fresh scraps of adhesive from the tile surface. For travertine that might have cracks on the lower side, we recommend to apply adhesive on both the tile and the underlay.
For a professional installation, apply adhesive on both underlay and tile.
Important! Do not step over tile surface, before adhesive is dried. Allow it to dry for 3 hours (for adhesives with rapid fixing) or even 4 hours (for a standard adhesive).
Read also the continuation of this: cutting tiles, sealing and grouting.


Working behind the scenes, Dr. Hannemann volunteered his time and talents tirelessly for fifteen years helping the Robotic Competition grow, expand and develop into the competition it is today. From its humble beginnings in 1986, with two work cell and two pick and place competitions, the current competition offers contests for elementary to post-secondary students in a wide range of categories.
Dr. Hannemann obtained his BS degree in Agricultural Education from South Dakota State University, an MS in Agriculture from Cornell University and a Ph.D. in Secondary Curriculum from Michigan State University. He worked as a Vocational Education Consultant for Oakland Intermediate School District (Michigan) from 1968 to 2000 when he retired. Dr. Hannemann served many schools, teachers and students and he loved his work. He took joy in experience and discovery – of places, foods, music, ideas and most importantly, people. He was an active member of the FFA, the Society of Manufacturing Engineers, the Automotive Industry Planning Council, VPAC, and ACTE. In 1999 he received the Presidents Award for outstanding service to ACTE.
In recognition of Dr. Hannemann's years of service to the RI/SME Student Robotic Competition, now the National Robotics Challenge, and to the thousands of students he touched, the National Robotics Challenge has established the Dr. James Hannemann Leadership and Service Award. This award is given annually at the National Robotics Challenge awards ceremony by the directors of the National Robotics Challenge.


The real issues for most people are the "open" GMT rolex replica sale dial, as well as the skeletonized hands. The integration of the annual calendar continues to be clever as the rolex replica sale month indicator is actually a window on the outside of the the respectively numbered hour rolex replica sale indicator. Thus, a window filled in at 2 o'clock would mean it was February. The window filled in at 6 o'clock would be June, etc... This, of course, is in rolex replica sale combination with the traditional date window which once rolex replica sale again has been fitted with a magnifier crystal over it on the sapphire crystal. While Rolex does have the GMT-Master II and the replica watches uk Explorer II as their major GMT watches, the rolex replica sale Sky-Dweller does it a little bit differently, offering yet another GMT watch, but with an indicator disc versus a hand.


Opening Day is here and '07 looks to be just as exciting as '06 as a lot of talented rookies play in their 1st full season. Delmon Young, Alex Gordon & B.J. Upton, Chris B. Young, Daisuke Matsuzaka, Kevin Kouzmanoff, Troy Tulowitzki & Stephen Drew start the season in the big leagues, while Philip Hughes, Homer Bailey, Ryan Braun, Hunter Pence, James Loney & many other Future Rookie Superstars who will be called up within the first few months. This past weekends Big 1-Year Anniversary was an enormous success with a record setting weekend for transactions on ThePit. A record setting number of users took advantage of the free cash giveaways and prizes. The final leaderboard for the top 30 buyers will be posted later this afternoon.


text:
Q: ExtJS. Refresh page after Delete I have instance of operation entity. I'd like to execute it after some row was successfully deleted from store (ui has been gotten OK response from server).
1st Issue. How determine that row was deleted on server and execute some logic after it.
There are no callbacks for store.remove/removeAt. And it seams (from debugging) that listening 'remove' event on store is not option.
2nd Issue. It's possible just to call execute() on operation instance. But how to get know view and even store about this operation. Because simple operation.execute() does not give any effect except request to back-end.

A: Solution to 1st issue:
store.suspendAutoSync();
    store.removeAt(this.rowIndex);
    this.getView().getStore().sync({
        success:function(){
            ...
        },
        failure:function(){
            ...
        }
    });


text:
Native American Tribes: The History of the Blackfeet and the Blackfoot Confederacy
By: Charles River Editors
Narrated by: Jack Chekijian
Categories: History, Americas
My Life as an Indian: The Story of a Red Woman and a White Man in the Lodges of the Blackfeet
By: James Willard Schulz
Narrated by: Rodney Louis Tompkins
First published in 1907, My Life as an Indian is the memoir of James Willard Schultz and tells the story of his first year living with the Pikuni tribe in Montana. It includes accounts of religious customs and ceremonies, hunting, raids, food preparation, child-rearing and more, and is thus of great interest to anthropologists and students of Native American history.
Horrible narrator
By The Fat Man on 11-13-19
Native American Tribes: The History and Culture of the Cherokee
Narrated by: Scott Larson
From the "Trail of Tears" to Wounded Knee and Little Bighorn, the narrative of American history is incomplete without the inclusion of the Native Americans that lived on the continent before European settlers arrived in the 16th and 17th centuries. Since the first contact between natives and settlers, tribes like the Sioux, Cherokee, and Navajo have both fascinated and perplexed outsiders with their history, language, and culture.
Very informative for such a short audiobook.
By Hish King on 05-28-15
The Wind Is My Mother
The Life and Teachings of a Native American Shaman
By: Bear Heart, Molly Larkin - contributor
Narrated by: Larry Winters
With eloquent simplicity, one of the world's last Native American medicine men demonstrates how traditional tribal wisdom can help us maintain spiritual and physical health in today's world.
Deep and powerful communication
By: Bear Heart, and others
The Journey of Crazy Horse
A Lakota History
By: Joseph M. Marshall III
Narrated by: Joseph M. Marshall III
Most of the world remembers Crazy Horse as a peerless warrior who brought the U.S. Army to its knees at the Battle of Little Bighorn. But to his fellow Lakota Indians, he was a dutiful son and humble fighting man who, with valor, spirit, respect, and unparalleled leadership, fought for his people's land, livelihood, and honor. In this fascinating biography, Joseph Marshall, himself a Lakota Indian, creates a vibrant portrait of the man, his times, and his legacy.
By William on 05-31-05
The History and Culture of the Shoshone
Narrated by: Scott Clem
Absolutely horrible
By Max Pritikin on 09-02-18
Nine Years Among the Indians, 1870-1879
The Story of the Captivity and Life of a Texan Among the Indians
By: Herman Lehmann
Narrated by: John McLain
As a young child, Herman Lehmann was captured by a band of plundering Apache Indians and remained with them for nine years. This is his dramatic and unique story. His memoir, fast-paced and compelling, tells of his arduous initial years with the Apache as he underwent a sometimes torturous initiation into Indian life. Peppered with various escape attempts, Lehmann's recollections are fresh and exciting in spite of the years past.
Fascinating read
By Turnthepage on 03-28-20
Rising Wolf, the White Blackfoot
By: James Willard Schultz
Narrated by: Brian Richy
J. W. Schultz (1859-1947) was an author, explorer, and historian who lived among the Blackfeet as a fur trader. In his famous book Rising Wolf, Schultz tells the story of Hugh Monroe who came to the Blackfoot country when he was 16 and was adopted into the Blackfeet tribe. He accompanied war parties, took part in buffalo hunts, and helped to make peace between the Crows and Blackfeet.
The Arawak: The History and Legacy of the Indigenous Natives in South America and the Caribbean
Narrated by: Dan Gallagher
The Arawak: The History and Legacy of the Indigenous Natives in South America and the Caribbean examines the culture and history of the indigenous groups and what happened when they came into contact with the Europeans. You will learn about the Arawak like never before.
good content, terrible pronunciation by reader.
By takajej on 11-04-19
Native American Tribes: The History and Culture of the Cheyenne
Narrated by: Todd Van Linda
One of the most famous Native American tribes on the Great Plains is the Cheyenne, and their fame may be surpassed only by their influence on American history. The Cheyenne shifted from a sedentary agricultural society to the kind of nomadic group many envision when thinking of groups on the Plains. Land disputes and conflicts with white settlers and the Cheyenne set in motion the chain of events that led to the most famous battle among Native Americans and the American government: the Battle of the Little Bighorn.
Eye opening overview of the journey, and strife.
By jimmy mihalik on 12-08-18
My Life as an Indian
Narrated by: Brian V. Hunt
Beautiful, tender, haunting, and full of excitement, this is the memoir of famed author, explorer, Glacier Park guide, trader, and historian of the Blackfoot Indians, James Willard Schultz. With the Blackfoot woman, whom he deeply loved, from 1880 to 1903, Schultz lived the life of a Blackfoot Indian with Nat-ah-ki and her people. During this time, he began writing for magazines, at times running a trading post, and working as a guide in the West.
Compassionate Story
By Ann Holmes on 09-13-18
Iroquoia: The Development of a Native World
Iroquois & Their Neighbors
By: William Engelbrecht
Narrated by: Caleb Rector
Drawing on archaeology, historical evidence, oral traditions, and linguistics, this audiobook provides a view of Iroquois life from the prehistoric period and Owasco sites through the establishment of the Five Nations/
By Lori on 02-09-18
The Medicine Bag
Shamanic Rituals & Ceremonies for Personal Transformation
By: Don Jose Ruiz
Narrated by: George Kastrinos
One of the main tenets of shamanism is a belief in the power of ceremony to manifest change in the physical world. Virtually all shamanic traditions use a variety of ritual practices as tools for personal transformation, healing, and celebration. Now, in this exciting and practical book, Toltec shaman and New York Times best-selling author don Jose Ruiz introduces and explains a wealth of these shamanic rituals and ceremonies, and provides a detailed and accessible guide to performing them on your own.
reminder of the power we all have within
Native American Tribes: The History and Culture of the Chippewa
Narrated by: David Zarbock
Outside of the Midwest, the Chippewa are not as well known as other Native American tribes like the Sioux or Cherokee, but they have long been one of the biggest groups in all of North America. Not surprisingly their presence around the Great Lakes region made them especially important to early European explorers who sailed the St. Lawrence and came into contact with the natives as they continued searching for the Northwest Passage.
Native American Tribes: The History and Culture of the Mound Builders
Narrated by: James Weippert
In the 18th century, when Europeans first came upon the giant mounds and earthworks dotting the North American landscape, they couldn't imagine that the Native Americans they came into contact with were capable of producing such advanced technology and masterful engineering. In fact, when President George Washington sent Rufus Putnam to survey land in southeastern Ohio, Putnam reported that he'd discovered an impressive walled earthwork complex, which was obviously the work of some long-forgotten ancient civilization.
A great bedtime book
The Indian World of George Washington
The First President, the First Americans, and the Birth of the Nation
By: Colin G. Calloway
Narrated by: Paul Heitsch
Colin Calloway uses the prism of George Washington's life to bring focus to the great Native leaders of his time and the tribes they represented: the Iroquois Confederacy, Lenape, Miami, Creek, Delaware; in the process, he returns them to their rightful place in the story of America's founding. The Indian World of George Washington spans decades of Native American leaders' interactions with Washington, from his early days as surveyor of Indian lands to his military career against both the French and the British to his presidency.
Detailed and 3-Dimensional
By Jeff on 06-04-20
The Last of the Mohicans [Classic Tales Edition]
By: James Fenimore Cooper
Narrated by: B. J. Harrison
It's 1757. The fate of North America is in the hands of the French, the British, and the Native Americans. Each party weaves its warlike path in this tapestry of adventure. Meet Hawkeye, Uncas, and Chingatchgook - each a stealthy iron-browed warrior of the mystifying forest. Discover the unscrupulous and sinister Magua, banished and determined to become the leader of his people.
Classic But Not Realistic View Of Native Americans
By Wade Lancaster on 11-16-19
Native American Tribes: The History and Culture of the Apache
Among all the Native American tribes, the Spanish, Mexicans, and Americans learned the hard way that the warriors of the Apache were among the fiercest in North America. Based in the Southwest, the Apache fought all three in Mexico and the American Southwest, engaging in seasonal raids for so many centuries that the Apache struck fear into the hearts of all their neighbors. Given the group's reputation, it's fitting that they are inextricably associated with one of their most famous leaders, Geronimo.
Performance Okay, Content Excellent
By Janet on 12-06-17
Native American Tribes: The History and Culture of the Arapaho
One of the most influential Native American tribes on the Great Plains was the Arapaho, a group so renowned among neighboring Native Americans that it's believed their name came from a Pawnee word for "trader. Like other notable Plains tribes, the Arapaho split off from other groups around the 16th-17th centuries and shifted from a sedentary agricultural society to the kind of nomadic group many envision when thinking of groups on the Plains.
They call themselves "Niitsitapi" ("Original People"), but in the United States, they are known as the Blackfeet. In Canada, they are known by their more particular band names, one of which is Blackfoot, but regardless of the name, they are a tribe of Native American peoples ("First Nations" in Canada) who, until the modern time period, lived in small, decentralized bands and hunted the bison on the northern Great Plains. Stories vary, but the name "Blackfeet" or "Blackfoot," applied to them by others, may have come originally from their practice of dying their moccasin soles black. That said, their use of an Algonquian language group may indicate that they were relatively recent newcomers to the region from somewhere in the Northeast.
The territory of the Blackfeet, at its greatest extent, encompassed a vast area from the eastern Rocky Mountains of Alberta and Montana and extending several hundred miles out onto the Great Plains, around the upper reaches of the Saskatchewan River and its tributaries in Alberta and the upper reaches of the Missouri River and its tributaries in Montana. The area of the land most sacred to the Blackfeet is the Sweet Grass Hills, which are located just south of the Canadian border in the central part of Montana. These are a group of buttes forested with balsam firs rising several thousand feet above the surrounding plains and which can be seen for a considerable distance. This was also Napi's favorite resting place in the mythology of the Blackfeet. Young Blackfeet went up into the Hills on their vision quests and, as their predecessors had done for several thousands of years, left inscriptions and petroglyphs on the surface of the tall sandstone cliffs. Many of the stories told by the Blackfeet take place there.
©2012 Charles River Editors (P)2015 Charles River Editors
The Captivity of the Oatman Girls
The Cambrian Period
A Handful of Hard Men
The Wilderness Hunter
Pathologies of Power
What listeners say about Native American Tribes: The History of the Blackfeet and the Blackfoot Confederacy
People of the Northwest Territory
This is one entry of a series on the indigenous tribes of North America. While brief, it seems well researched and presented, and does provide a number of references and documentation. As expected, Charles River Editors have done a creditable job once again. The audio is narrated by Jack Chekijian, who is well known for excellence in this capacity.
This book is great for telling a quick history of the Blackfoot nation, it's great for helping to understand what people went through, good and bad. Everyone in the country should read this to understand some of the incredible injustices that were committed in our country's history
Shopsfromeverywhere
Worth the time
tool a chance on this one based on reviews and am glad I did, the only complaint I have is that the end seems to be done with little thought of how rushed it seemed.


text:
Chemistry Biology and Medical Earth Sciences Computer Science Computing and Technology DIY Projects
Biology and Medical
SARS-CoV-2 Mutations
Thread starter Ygggdrasil
covid-19 genomics mutation
Ygggdrasil
A general thread to collect the latest research on mutations to the SARS-CoV-2 virus.
Given the seeming increased transmissibility of the new SARS-CoV-2 variants being identified, I thought I'd start a general thread to collect and organize information on the various mutations to the SARS-CoV-2 virus.
B.1.1.7 variant (aka 20B/501Y.V1, VOC 202012/01; originally identified in the UK):
This variant is characterized by 14 lineage-specific amino acid replacements and three deletions. Of most concern are:
The N501Y mutation within the receptor binding domain (RBD) of the spike (S) protein, which is thought to increase the binding affinity to human ACE2
Deletion of residues 69-70 in the S protein which may be involved in evading the human immune response
The P681H mutation in the S protein, which are adjacent to the furin cleavage site
Initial report from COG-UK describing the variant: https://www.cogconsortium.uk/wp-con...-2020_SARS-CoV-2-Mutations_final_updated2.pdf
Pre-print manuscript more fully characterizing the vairant: https://virological.org/t/prelimina...defined-by-a-novel-set-of-spike-mutations/563
Report from Imperial College London with epidemiological data suggesting increased transmissibility of the variant: https://www.imperial.ac.uk/media/im...2020-12-31-COVID19-Report-42-Preprint-VOC.pdf
Pre-print showing that the Pfizer vaccine elicits antibodies that recognize viruses containing the N501Y mutation in the S protein: https://www.biorxiv.org/content/10.1101/2021.01.07.425740v1
Pre-print study characterizing the S protein 69-70 deletion: https://www.medrxiv.org/content/10.1101/2020.12.05.20241927v3
B.1.351 variant (aka 20C/501Y.V2; originally identified in South Africa):
This variant is characterized by eight lineage-defining mutations, including the mutation of three important residues in the S protein RBD (K417N, E484K and N501Y).
Pre-print describing the identification of the variant: https://www.krisp.org.za/publications.php?pubid=315
Pre-print suggesting that the E484K mutation could evade immunity: https://www.biorxiv.org/content/10.1101/2020.12.31.425021v1
D614G mutation:
This mutant was observed early in the pandemic and has since become widespread.
Published, peer-reviewed study identifying the spread of the mutation: https://www.sciencedirect.com/science/article/pii/S0092867420308205?via=ihub
Various published, peer-reviewed studies evaluating the role of D614G mutation in affecting the transmissibility of the virus:
SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo: https://science.sciencemag.org/content/370/6523/1464
Spike mutation D614G alters SARS-CoV-2 fitness: https://www.nature.com/articles/s41586-020-2895-3
Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity: https://www.cell.com/cell/fulltext/S0092-8674(20)31537-3
Nice article in JAMA discussing the mutants: https://jamanetwork.com/journals/jama/fullarticle/2775006
CDC page on emerging SARS-CoV-2 variants: https://www.cdc.gov/coronavirus/201...earch/scientific-brief-emerging-variants.html
Likes bhobba, Useful nucleus, jim mcnamara and 9 others
Note that widespread transmission of a new variant does not always mean that the new variant is a more transmissible form of the virus. Often, certain variants could be spread more widely by chance (e.g. they happen to get spread at a superspreader event). Here's a good example of the 20A.EU1 variant that emerged in Spain early in the summer and became widespread across Europe, yet researchers subsequently found no evidence that the variant itself had showed increased transmissibility. Rather, the researchers attribute the success of the variant to it being present in the right place at the right time (emerging just as travel and quarantine restrictions were being lifted in Europe).
Emergence and spread of a SARS-CoV-2 variant through Europe in the summer of 2020
Hodcroft et al. medRxiv. Nov 27, 2020
Following its emergence in late 2019, SARS-CoV-2 has caused a global pandemic resulting in unprecedented efforts to reduce transmission and develop therapies and vaccines (WHO Emergency Committee, 2020; Zhu et al., 2020). Rapidly generated viral genome sequences have allowed the spread of the virus to be tracked via phylogenetic analysis (Hadfield et al., 2018; Pybus et al., 2020; Worobey et al., 2020). While the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced, allowing continent-specific variants to emerge. However, within Europe travel resumed in the summer of 2020, and the impact of this travel on the epidemic is not well understood. Here we report on a novel SARS-CoV-2 variant, 20A.EU1, that emerged in Spain in early summer, and subsequently spread to multiple locations in Europe, accounting for the majority of sequences by autumn. We find no evidence of increased transmissibility of this variant, but instead demonstrate how rising incidence in Spain, resumption of travel across Europe, and lack of effective screening and containment may explain the variant's success. Despite travel restrictions and quarantine requirements, we estimate 20A.EU1 was introduced hundreds of times to countries across Europe by summertime travellers, likely undermining local efforts to keep SARS-CoV-2 cases low. Our results demonstrate how genomic surveillance is critical to understanding how travel can impact SARS-CoV-2 transmission, and thus for informing future containment strategies as travel resumes.
Likes bhobba, Laroxe, pinball1970 and 1 other person
This paper may be of interest: https://www.biorxiv.org/content/10.1101/2021.01.07.425740v1.full.pdf
It is a pre-publication of data about the effectiveness of the Pfizer vaccine against the N501Y variant.
I've also made some Youtube videos on my channel going through the literature on many of these subjects:
Ygggdrasil said:
Summary:: A general thread to collect the latest research on mutations to the SARS-CoV-2 virus.
I hope it's not a hijack, then. As far as I understand PCR is about multiplying a possibly present target sequence up to a detectable level.
How sensitive this method to different strains? I mean, when the mutation making the strain makes the 'reference' part of viral genome different than the 'target'?
Rive said:
Yes, the RT-qPCR tests for COVID-19 rely on detecting specific RNA sequences in the virus' RNA genome, and mutation of those sequences could cause the test to give a false negative. In fact, this does seem to be the case with the B.1.1.7 variant, where the 69-70del of the S gene prevents some RT-qPCR tests from detecting the presence of the S gene.
However, the RT-qPCR tests were designed with the idea that the virus could mutate in mind. All of the RT-qPCR tests look for multiple, independent regions of the virus, so even if mutation interferes with detection of the virus at one site, the test would still be able to detect the other sites of the virus RNA. Indeed, people have been able to track the B.1.1.7 variant by seeing RT-qPCR tests that are positive for two markers (N and Orf1ab), but negative for the third marker (S).
It is possible to design RT-qPCR tests that are specific for certain strains of the virus, and researchers have developed such tests for the B.1.1.7 variant. It is also possible to design new RT-qPCR tests that will detect all common variants (by making use of existing sequencing data on the various common circulating strains of the virus).
Likes msumm21, bhobba, pinball1970 and 3 others
Thank you for the answer, it is really informative. I know about some cases where the symptoms were conclusive but multiple (!) PCR tests were negative. This were buggin' me for some time already
Jarvis323
A new strain has been discovered in Japan.
The variant of the virus discovered in Japan belongs to the B.1.1.248 strain and has 12 mutations in the spike protein, the NIID said.
https://news.google.com/articles/CA...2Nb3CjDivdcCMJ_5ngY?hl=en-US&gl=US&ceid=US:en
Jarvis323 said:
Here's the official report from the Japanese National Institute of Infectious Diseases: https://www.niid.go.jp/niid/en/2019-ncov-e/10108-covid19-33-en.html
Here's a good figure from the report comparing the spike protein mutations found in the B.1.1.248 strain found in Japan to other strains:
The strain contains the N501Y mutation that is thought to increase the strength of binding of the virus' spike protein to the ACE2 receptor on cells in the body as well as the E484K mutation that could be involved in evading antibody-based immunity.
Likes bhobba, Rive and Jarvis323
Here's a report of a new strain from Manaus, Brazil called the P.1 lineage. It has 17 unique amino acid changes, 3 deletions, and 4 synonymous mutations, and one 4nt insertion compared to the next most closely related strain (B.1.1.28):
https://virological.org/t/genomic-c...-2-lineage-in-manaus-preliminary-findings/586
Of interest are three mutations in the S protein RBD region that are known to be of importance, E484K, K417T and N501Y. The N501Y mutation is also found in the B.1.1.7 lineage from the UK and the B.1.351 lineage from South Africa and is through to potentially increase the transmissibility of the virus by increasing the affinity of the S protein for human ACE2 receptors. The E484K mutation (also found in the B.1.351 lineage) could be involved in evading antibody-based immunity.
The P.1 lineage is very similar to the B.1.1.248 lineage reported above from Japan, which is expected given that the strain was identified in four individuals who had arrived in Tokyo from Amazonas, Brazil.
Virologist Trevor Bedford had a good thread discussing the emergence of the new coronavirus strains:
He maintains nextstrain.org which is a good resource for tracking the genomic data available for SARS-CoV-2. Here are some plot from that site showing how the incidence of mutations at E484 (potentially associated with escaping antibody responses) and N501 (potentially increasing transmission) have changed over time:
N501:
E484:
Both mutation seem to have emerged relatively recently and increased in prevalence, though it seems like the prevalence of the E484K may be going down while the N501Y and related mutations still appear to be increasing in prevalence (though these numbers could be biased by increased efforts to monitor the spread of the B.1.1.7 strain in the UK and elsewhere).
[edit: for comparison here's the plot for the D614G mutation which emerged early on during the pandemic and has become the most prevalent form of the virus:]
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Laroxe
A few links that people might feel are interesting:
Prof Vincent Racaniello discusses mutation in the SARS-COV 2 virus and why he's unimpressed by the alarmist headlines we see. He frequently makes the point that these changes should be seen as variants they are not new strains.
Then in the Vblog TwiV 708 they discuss a paper that identifies a new type of antibody that has implications for the prevention and treatment of SARS-COV 2 and other viral infections, called nanobodies. These are found naturally in Alpacas and some other animals and seem to offer a range of new possibilities. The discussion on Twiv starts at around 58 minutes and gives rather more information than this discussion at science daily, the paper itself is behind a paywall.
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A non-peer reviewed pre-print reports the emergence of several new variants in the US that have all acquired mutations at position 677 of the spike (S) protein:
While it is not yet known whether these mutation affect the transmissibility or ability of the virus to be recognized by the immune system, the mutation does occur near the furin cleavage site of the S protein, suggesting that these mutations could have some effect on the virus.
Surveilance sequencing data from Nextstrain does not seem to show a clear pattern of rapid spread of viruses containing these variants yet, however:
https://nextstrain.org/ncov/global?c=gt-S_677
Here's a citation to the study:
Emergence in late 2020 of multiple lineages of SARS-CoV-2 Spike protein variants affecting amino acid position 677
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) plays critical roles in host cell entry. Non-synonymous substitutions affecting S are not uncommon and have become fixed in a number of SARS-CoV-2 lineages. A subset of such mutations enable escape from neutralizing antibodies or are thought to enhance transmission through mechanisms such as increased affinity for the cell entry receptor, angiotensin-converting enzyme 2 (ACE2). Independent genomic surveillance programs based in New Mexico and Louisiana contemporaneously detected the rapid rise of numerous clade 20G (lineage B.1.2) infections carrying a Q677P substitution in S. The variant was first detected in the US on October 23, yet between 01 Dec 2020 and 19 Jan 2021 it rose to represent 27.8% and 11.3% of all SARS-CoV-2 genomes sequenced from Louisiana and New Mexico, respectively. Q677P cases have been detected predominantly in the south central and southwest United States; as of 03 Feb 2021, GISAID data show 499 viral sequences of this variant from the USA. Phylogenetic analyses revealed the independent evolution and spread of at least six distinct Q677H sub-lineages, with first collection dates ranging from mid-August to late November 2020. Four 677H clades from clade 20G (B.1.2), 20A (B.1.234), and 20B (B.1.1.220, and B.1.1.222) each contain roughly 100 or fewer sequenced cases, while a distinct pair of clade 20G clusters are represented by 754 and 298 cases, respectively. Although sampling bias and founder effects may have contributed to the rise of S:677 polymorphic variants, the proximity of this position to the polybasic cleavage site at the S1/S2 boundary are consistent with its potential functional relevance during cell entry, suggesting parallel evolution of a trait that may confer an advantage in spread or transmission. Taken together, our findings demonstrate simultaneous convergent evolution, thus providing an impetus to further evaluate S:677 polymorphisms for effects on proteolytic processing, cell tropism, and transmissibility.
Popular press coverage: https://www.nytimes.com/2021/02/14/health/coronavirus-variants-evolution.html
Also, the NYTimes has published a nice webpage compiling information on the coronavirus variants: https://www.nytimes.com/interactive/2021/health/coronavirus-variant-tracker.html
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Astronuc
Staff Emeritus
And now, CAL.20C, or 20C/S:452R;/B1429, and B.1.525
https://www.cidrap.umn.edu/news-per...vid-variant-5-mutations-identified-california
https://cov-lineages.org/global_report_B.1.525.html
https://www.bbc.com/news/health-56082573
https://bc.ctvnews.ca/b-c-identifie...5-associated-with-travel-to-nigeria-1.5307360
B.1.525 appears similar to the South African variant which prompted door-to-door tests in areas where it has been found.
Tom.G
And the New England Journal of Medicine published a preliminary report that the South African variant, B.1.351, is one third as susceptible to vaccine-induced antibodies as the original virus is.
https://nypost.com/2021/02/18/pfize...w-weaker-results-against-south-africa-strain/
However, it's unclear if reduced antibody response will render the vaccine ineffective against the strain, since it's not known what level is necessary to neutralize the virus.
"We don't know what the minimum neutralizing number is. We don't have that cutoff line," study co-author Pei-Yong Shi said.
https://www.nejm.org/doi/full/10.1056/NEJMc2102017
...neutralization of the B.1.351-spike virus was weaker by approximately two thirds. Our data are also consistent with poorer neutralization of the virus with the full set of B.1.351-spike mutations than virus with either subset of mutations and suggested that virus with mutant residues in the receptor-binding site (K417N, E484K, and N501Y) is more poorly neutralized than virus with Δ242-244, which is located in the N-terminal domain of the spike protein.
Other reports state that all the vaccine manufacturers are willing and ready to modify their vaccines if needed.
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Astronuc said:
It seams that the new California variant B.1.427/B.1.429 is a much more contagious and deadly strain of the virus.
A coronavirus variant that emerged in mid-2020 and surged to become the dominant strain in California not only spreads more readily than its predecessors, but also evades antibodies generated by COVID-19 vaccines or prior infection and is associated with severe illness and death, researchers said.
In a study that helps explain the state's dramatic surge in COVID-19 cases and deaths — and portends further trouble ahead — scientists at UC San Francisco said the cluster of mutations that characterizes the homegrown strain should mark it as a "variant of concern" on par with those from the United Kingdom, South Africa and Brazil.
"The devil is already here," said Dr. Charles Chiu, who led the UCSF team of geneticists, epidemiologists, statisticians and other scientists in a wide-ranging analysis of the new variant, which they call B.1.427/B.1.429. "I wish it were different. But the science is the science."
The new analysis is currently under review by the public health departments of San Francisco County and the state, which collaborated in the new research. It is expected to post late this week to MedRxiv, a website that allows new research to be shared before its formal publication.
https://www.yahoo.com/news/californias-coronavirus-strain-looks-increasingly-130055544.html
@Ygggdrasil I know this is an article, but the sources seem credible, there is a lot of information that's new to me, but you may already be familiar with. I'd like your take on the information.
Evo said:
Given that the Yahoo article says that a pre-print of the study will be posted later in the week, I'll probably reserve judgement until the data are published. In general, it can be difficult to collect data to determine whether a new variant is more transmissible or more deadly.
One paper found that one of the mutations found in the CAL.20C strain, the L452R mutation in the receptor binding domain of the S protein, could potentially allow the virus to escape neutralization by some antibodies. However, most of the antibodies they tested (including convalescent sera) were able to neutralize virus with the L452R mutation and viruses with the L452R mutation did not seem to be more infective than the regular variant. However, L452R is not the only mutation in the CAL.20C strain, so the lab experiments might not be fully indicative of the behavior of the variant.
Data from NextStrain suggests that L452R variants are increasing in prevalence, so it is possible that it could be more contagious.
However, as I noted in post #2, we have seen variants become highly prevalent during major outbreaks of the disease (such as those experienced in California this winter), but those variants became prevalent just by being in the right place at the right time without being inherently more contagious, so we need more data than just seeing a high prevalence of the new variant. For example, for the B.1.1.7 variant (which we do believe to be more highly contagious), researcher were able to see higher viral loads in infected patients and epidemiological modeling suggested that the virus did exhibit greater transmissiblity (along with molecular biology work showing that specific mutations in the B.1.1.7 strain allow the S protein to bind to the ACE2 receptor more strongly).
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According to UCSF, they have a number of studies going on in the state.
According to this release, https://www.ucsf.edu/news/2021/02/4...e-coronavirus-variants-san-franciscos-mission, ""The research indicates that the household secondary attack rate of the L452R variant identified in the Mission District appears to be higher than other rates that have been measured within the United States and globally, but more work needs to be done to confirm these findings."
The Yahoo article cites an LA Times article about the CA (homegrown) variant, and various other media outlets are reporting on variants with greater transmissibility.
Also - https://www.ucsf.edu/news/2021/01/419561/how-worried-should-you-be-about-new-coronavirus-variant
Likes jim mcnamara and Evo
Yet another variant, B.1.526, "which first appeared in samples collected in the city in November. By the middle of this month, it accounted for about one in four viral sequences appearing in a database shared by scientists."
One study of the new variant, led by a group at Caltech, was posted online on Tuesday. The other, by researchers at Columbia University, has been submitted to a preprint server but is not yet public.
Neither study has been vetted by peer review nor published in a scientific journal. But the consistent results suggest that the variant's spread is real, experts said.
The E484K mutation has independently cropped up in many different parts of the world, an indication that it offers the virus a significant advantage.
"Variants that have an advantage are going to rise pretty fast in frequency, especially when numbers are coming down over all," said Andrew Read, an evolutionary microbiologist at Penn State University.
Dr. Ho's team reported in January that the monoclonal antibodies made by Eli Lilly, and one of the monoclonal antibodies in a cocktail made by Regeneron, are powerless against the variant identified in South Africa.
And several studies have now shown that variants containing the E484K mutation are less susceptible to the vaccines than was the original form of the virus. . . .
https://www.nytimes.com/2021/02/24/health/coronavirus-variant-nyc.html
Caltech - SARS-CoV-2 lineage B.1.526 emerging in the New York region detected by software utility created to query the spike mutational landscape
The most common sets of spike mutations in this lineage (now designated as B.1.526) are L5F, T95I, D253G, E484K or S477N, D614G, and A701V. This lineage appeared in late November 2020, and isolates from this lineage account for ~25% of coronavirus genomes sequenced and deposited from New York during February 2021.
https://www.biorxiv.org/content/10.1101/2021.02.14.431043v2.full.pdf
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A few recent papers studying coronavirus variants:
Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity
https://www.cell.com/cell/fulltext/S0092-8674(21)00080-5
Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine induced sera
No higher infectivity but immune escape of SARS-CoV-2 501Y.V2 variants
Recurrent deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
https://science.sciencemag.org/content/early/2021/02/02/science.abf6950
Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera
Neutralization of SARS-CoV-2 lineage B.1.1.7 pseudovirus by BNT162b2 vaccine–elicited human sera
https://science.sciencemag.org/content/early/2021/01/28/science.abg6105
SARS-CoV-2 spike D614G change enhances replication and transmission
mRNA vaccine-elicited antibodies to SARS-CoV-2 and circulating variants
Likes bhobba
New paper with more data supporting increased transmissibility of the B.1.1.7 variant:
Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England
A novel SARS-CoV-2 variant, VOC 202012/01 (lineage B.1.1.7), emerged in southeast England in November 2020 and is rapidly spreading toward fixation. Using a variety of statistical and dynamic modelling approaches, we estimate that this variant has a 43–90% (range of 95% credible intervals 38–130%) higher reproduction number than preexisting variants. A fitted two-strain dynamic transmission model shows that VOC 202012/01 will lead to large resurgences of COVID-19 cases. Without stringent control measures, including limited closure of educational institutions and a greatly accelerated vaccine roll-out, COVID-19 hospitalisations and deaths across England in 2021 will exceed those in 2020. Concerningly, VOC 202012/01 has spread globally and exhibits a similar transmission increase (59–74%) in Denmark, Switzerland, and the United States.
Like most of these early reports, people can get a bit carried away, it does seem that B.1.1.7 is more transmissable, but this is surprisingly difficult to be sure about. In certain areas it has become the most common variant but in others, where it is clearly present it doesn't seem to be out competing the established variant. Of course reguardless, it doesn't change much, we will still be trying to control the spread using the current behavioural strategies until vaccines prevent its spread.
The variants with changes in the spike protien are of more concern (B.1.427/B.1.429) but again headlines which describe them as more deadly are alarmist nonsense. These variants have altered one or more of the protien antigens targeted by current vaccines, this means that antibodies produced in reaction to infection or vaccination based on the original variants have fewer binding sites and so offer less protection. For a virus to become totally resistant to these antibodies requires multiple changes and takes time though it is the case that when the infection is so common there is a much greater opportunity for mutations to occur.
So while these variants do reduce the effectiveness of vaccines there is no evidence that they are rendered totally ineffective and vaccination is still indicated. There are already several vaccine manufacturers adapting their vaccines in order to address these problems, there are also some vaccines still in development that target a wider range of epitomes that may help. Its likely that they will need to do this several times, the virus will continue to change, thats what viruses do.
Likes Evo
The new version that surfaced in Portland has the same backbone as B.1.1.7, and the mutation it carries — E484K, or "Eek" — is one seen in variants of the virus circulating in South Africa, Brazil and New York City.
https://www.nytimes.com/live/2021/0...rsion-of-a-variant-first-identified-in-the-uk
The B.1.1.7 variant with Eek also has emerged in Britain, but the virus identified in Oregon seems to have evolved independently, Dr. O'Roak said.
Dr. O'Roak and his colleagues found the B.1.1.7 variant with Eek among coronavirus samples collected by the Oregon State Public Health Lab from an outbreak in a health care setting. Of the 13 test results they analyzed, 10 turned out to be B.1.1.7 alone, and one the combination.
Did B.1.1.7 variant with Eek develop independently, or it was community spread without evidence of the transmission? Portland has an international population.
Nature, March 05 - Multitude of coronavirus variants found in the US — but the threat is unclear
Ramped-up sequencing efforts are helping to identify mutations that might boost transmission or help a virus evade immune responses.
https://www.nature.com/articles/d41586-021-00564-4
The New York Times reports that cases of B.1.1.7 infections in the US seem to be rising while overall COVID-19 cases have been falling, which adds more evidence for the increased infectivity of the B.1.1.7 variant:
https://www.nytimes.com/interactive/2021/03/06/us/coronavirus-variant-sequencing.html
This trend also seems to be apparent in most of the states they analyzed. Luckily, most studies suggest that the B.1.1.7 variant can be controlled by the current set of vaccines authorized for use in the US. However, if this variant begins gaining mutations such as E484K ("eek") that seem to lower vaccine efficiency, this could pose problems for containment (though this depends on the extent to which the vaccines still protect against severe disease and hospitalization even if they are less effective at preventing symptomatic disease).
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I was wondering - is the E484K mutation unique to SARS-Cov-2? Is it something that develops from the host?
Meanwhile (12/21/2020, updated February 17th?) - Solutions for surveillance of the S gene mutation in the B.1.1.7 (501Y.V1) SARS-CoV-2 strain lineage
https://www.thermofisher.com/blog/b...in-the-b117-501yv1-sars-cov-2-strain-lineage/
E484 of the spike protein falls within the receptor binding domain, which is a fairly variable region within the protein (likely b/c it need to evolve new mutations as it the virus moves to new hosts). For example, the equivalent position in the original SARS-CoV virus (which caused the 2002-2003 outbreaks) has a proline instead of a glutamic acid at the equivalent position. Given the evidence that the E484K mutation helps the virus escape antibody-based immunity, it is likely that the mutation arose as an adaptation to transmitting in human hosts.
Although various studies suggest that the E484K and other mutations could help the new variants escape antibody-based immunity, it is important to remember that there is another arm to the adaptive immune response that involves T-cells. Anew, non-peer reviewed pre-print study suggests that the T-cells which develop in response to either COVID-19 infection or vaccination all seem to still be effective against the various new variants:
Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees
https://www.biorxiv.org/content/10.1101/2021.02.27.433180v1
The emergence of SARS-CoV-2 variants highlighted the need to better understand adaptive immune responses to this virus. It is important to address whether also CD4+ and CD8+ T cell responses are affected, because of the role they play in disease resolution and modulation of COVID-19 disease severity. Here we performed a comprehensive analysis of SARS-CoV-2-specific CD4+ and CD8+ T cell responses from COVID-19 convalescent subjects recognizing the ancestral strain, compared to variant lineages B.1.1.7, B.1.351, P.1, and CAL.20C as well as recipients of the Moderna (mRNA-1273) or Pfizer/BioNTech (BNT162b2) COVID-19 vaccines. Similarly, we demonstrate that the sequences of the vast majority of SARS-CoV-2 T cell epitopes are not affected by the mutations found in the variants analyzed. Overall, the results demonstrate that CD4+ and CD8+ T cell responses in convalescent COVID-19 subjects or COVID-19 mRNA vaccinees are not substantially affected by mutations found in the SARS-CoV-2 variants.
This result is very positive news if true. The data suggest that, while the new variants may still be able to infect vaccinated individuals, the T-cell response would likely prevent those infections from leading to severe symptoms.
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Recounting the story of Christmas Day, the School Nativity is performed every December nationwide. Despite a slight decrease in the tradition of this particular story in British schools, who are now favouring other secular plays to accommodate varying faiths, the amount of organisation, planning, and time is likely to be no different.
With children dressed in costume and a choir of angels eagerly racking their brains for the words they've been practising for weeks on end, the school hall will undoubtedly turn into a slightly chaotic and excitable space for staff.
Setting the stage and scenery is necessary weeks prior to performance in order to practice accordingly. However, this likely causes an unwelcome distraction during assemblies, particularly for younger children. Did you know that you can calculate a child's attention span based on their age? Focusing on one task, a 5 year old is likely to only have an attention span of 5 minutes and so on.
Additionally the school hall is used for a multitude of activities including meetings, P.E. classes and potentially even examinations. Whilst rehearsals must continue, so do other such activities taking place within school buildings.
Many educational establishments face challenges with space, or the lack of it. And every educational establishment will equally understand that every useable space needs to be managed to accommodate the increasing range of activities.
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Operable Walls – individual panels are built using an isolated steel frame and a multiple material infill which contributes to an enhanced acoustic performance.
Fabric – available in four difference levels of sound reductions, 15dB, 24dB, 30dB, and 35dB we can cater to your specific sound proofing qualities.
Health and Safety is paramount in any educational facility.
Therefore we have designed our products to comply with Health and Safety regulations laid down by the Department of Education and Skills. Additionally our team will ensure you meet all the criteria detailed within the Governments Guide to Partitions in School as well as taking care of everything from product selection and system design through to full installation.
We even provide a full one year guarantee on all of our products as well as regular maintenance inspections as part of our after care service so you can rest assured you continue to meet health and safety obligations.
If you're in need of a moveable wall or folding partition to enhance and improve the available space in you school, why not give our knowledgeable and experience team a call on 01373 454577.


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Dead Person Of The Day November 9 – Ed Bradley
0 Comments 09 November 2011
Folks,
One hell of an American on tap for today's DPD. Bradley really did it all. Star college football player, wounded in action in Cambodia as a journalist, worked his way up the CBS ladder by starting as a disc jockey working for free in Philly and ending with his last role on 60 minutes. Unreal.
While doing my research I realized two things.
Number 1 – I'm shocked by how controversial wearing an earring was.
Number 2 – Having a jazz parade in NOLA to celebrate your perishing is pretty sick.
The above interview is fascinating. The MJ enigma is (as they say) a whole nother story.
ED BRADLEY (June 22, 1941 – November 9, 2006)
By Patricia Sullivan
Washington Post Staff Writer
Ed Bradley, 65, a suave and streetwise reporter considered one of the best interviewers on television and the winner of 19 Emmy awards for his work on "60 Minutes" and "CBS Reports," died of leukemia Nov. 9 at Mount Sinai Hospital in New York City. He lived in New York.
Bradley, the first African American at CBS to be a White House correspondent and a Sunday night anchor, covered a broad array of stories with insight and aplomb during his 39-year career, from war to politics to sensitive portraits of artists. He won virtually every broadcast news award — some of them more than once. Continue
Norman Orlando
Norman Orlando - who has written 512 posts on The Shade.
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