text:
Home / Cannabinoid News
Cannabinoids in neurodegenerative disorders: an overview
The endocannabinoid system, part of the body's onboard cell signaling network, plays a widely modulatory role in important functions in neurodegenerative disorders. These functions are known to include neurotransmission, glial activation, oxidative stress, and protein homeostasis. There is evidence that cannabinoids slow the progression of multiple sclerosis in particular, and offer some symptomatic relief as well, notably in spasticity. Data suggest that multiple targets in MS can be modulated all at once, opening the way to better disease management through interdiction of more than one mechanism of action simultaneously. There is also evidence for disease delay in amyotrophic lateral sclerosis (or 'ALS', or 'Lou Gehrig's disease' or 'motor neuron disease'). Here, cannabinoids are clearly active across the whole range of abnormal physiological processes, and they may even modulate the gene expression that drives the whole syndrome. In glaucoma and diabetic retinopathy, too, endocannabinoids and their synthetic cousins are turning out to have the right pharmacological profile not only to lower intraocular pressure, a critical part of treatment, but to target the associated neurodegenerative processes that underlie these diseases.
In separate posts we give you detailed examinations of the state of cannabinoid research in each of MS, ALS, and glaucoma. Here, as background, is an overview of what is broadly known at this point about whether and why cannabinoids work in neurodegenerative disorders in general.
At the fundamental level, several lines of evidence have suggested that the endocannabinoid system plays an important role in early neuronal development. For example, natural cannabinoids improve dopamine neurotransmission and tau and amyloid pathology in parkin-null, human tau overexpressing (PK-/-/TauVLW) mice, a model of complex frontotemporal dementia, Parkinsonism, and lower motor neuron disease. It is clear that both of the inhibitory G protein-coupled receptors CB1 and CB2 play central mediating roles, and also that additional receptors may be involved as well. Collectively, CB1 and CB2 receptor signaling contributes to the control of Ca2+ homeostasis, trophic support, mitochondrial activity, and inflammatory conditions. The level of expression of these receptors, and of downstream enzymes controlling endocannabinoid levels, undergo time- and brain region-specific changes during neurodegenerative and neuroinflammatory disorders.
CB1 receptors are mostly expressed in neurons, where they regulate neurotransmitter release and synaptic strength, and CB2 receptors are found mostly in glial cells and microglia, where they activate and over-express in disease. At CB1, anandamide and 2-arachidonoylglycerol are the two most studied agents in counteracting neurochemical imbalances. At CB2, lipophilic mediators regulate the activity and function of glia and microglia. The release of potentially neurotoxic compounds through astroglial hemichannels and pannexons has been implicated as one of the functional alterations that negatively affect the progression of multiple brain diseases. Recent insights have suggested that regulating the opening and closing of these channels specifically is where endocannabinoids could play an important role. In the normal brain, because they apparently elicit the Ca2+-activation of astrocyte hemichannels, these endocannabinoids may be of significant consequence in synaptic plasticity. Endocannabinoids also eem to counteract the activation of inflammatory pathways that lead to glia-mediated production of TNF-α and IL-1β, both well-known triggers of astroglial hemichannel opening.
Thus it is that research is focussing most on activity at the CB2 receptor site at the moment, recognizing also that the actions of agonists of CB1 receptors are psychotropic, and that there are as well serious side effects that accompany selective antagonists of this same receptor. Differential localization of CB2 receptors in neural cell types and upregulation in neuroinflammation are clearly keys to therapeutic potential, then. This is an important insight. Because of their wide expression in immune cells, CB2 receptors have traditionally been thought to act as peripheral receptors, so to speak. Their recent identification in brain areas and in distinct neuronal cells has made it reasonable to examine CB2 signaling in the context of brain pathophysiology, synaptic plasticity and neuroprotection.
Applied study of specific candidates for cannabinoid treatment in neurodegenerative disorders is still in its infancy. Cannabigerol (CBG) may emerge as a treatment against neuroinflammation and oxidative stress. CBG pre-treatment has been able to reduce the loss of cell viability induced by the medium of LPS-stimulated macrophages in NSC-34 cells. Pre-treatment with CBG also inhibits apoptosis, or cell death, demonstrated by the reduction of caspase 3 activation and Bax expression, while Bcl-2 levels at the same time increases. CBG pre-treatment has also counteracted inflammation, as shown by the reduction of IL-1&beta, TNF-&alpha, IFN-&gamma, and PPAR&gamma, and also oxidative stress in NSC-34 cells treated with the medium of LPS-stimulated RAW 264.7. Immunocytochemistry has shown, finally, that CBG pre-treatment also reduces nitrotyrosine, SOD1 and iNOS protein levels and restored Nrf-2 levels.
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The foregoing is a report on trends and developments in the cannabinoid industry. No product described herein is intended to diagnose, treat, cure or prevent any disease or syndrome.


We aim to despatch your order by return of post.
For out of stock items or goods made to specification, please allow up to 28 days. An estimated delivery can be provided upon request.
Refunds will be given (excluding postage) on goods returned in their original condition, NOT altered or worn.
Garments which have been embroidered or made to a non-standard specification cannot be returned unless faulty. Personalised goods cannot be returned.
The buyer is responsible for return postage. We recommend you ask for a 'Proof of Postage' free of charge from the post office, when returning goods. This covers insurance for up to £27 on lost post.
For more expensive items we recommend returning goods to be signed for or tracked, please ask post office for advice.
We ask for a £3.50 handling fee for exchanges to cover postage, administration and handling of returned goods.
We cannot accept responsibility for returns lost in the post when being sent to us. We log all returns upon receipt but during September this may take up to 48 hours.


Tuesday: The packing team arrived at our old house to pack everything. By the time they were done - mid-afternoon - the blizzard had set in with full force, and it was craziness. The boys had a snow day that day (and the next day was supposed to be their last day at their old school). Our dear neighbors had all the kids at their house to play that day, as our house was not much fun, what with all the TVs and video games packed up. So we picked up the boys after the packing team left, then drove to the hotel where we were supposed to be staying for a single night. That single night turned into three nights. The snow was insane! I've never seen anything like it. By early evening, the moving company had called to reschedule our loading from Wednesday to Thursday.
Wednesday: By morning, there was at least 12 inches of snow on the ground. Another snow day for the schools. Turns out the boys wouldn't be going back to their old school. :( They were okay with it, but I was sad for them. The best part: Byron and I spent three hours shoveling the driveway and the sidewalks in preparation for the loading team to come to the house to pack us up. We got a call mid-morning that the movers wouldn't be able to be there until Friday. So we went back to the hotel to stay another night.
Thursday: Even with the load being delayed, I knew the boys and I would have to go to Lincoln regardless. We had a carpet cleaning appt that afternoon at the new house, and the boys were supposed to start their new school the next day. So we left Byron to deal with the loading up of all our worldly possessions. Which is probably just as well, considering how freaked out I was just seeing all our stuff in boxes. The boys and I arrived in Lincoln and set up camp in our new house with air mattresses and suitcases.
Friday: I had called the new school from the road the day before and told them the boys wouldn't be starting until Monday. I just couldn't deal with one more thing - I admit it, I was stretched to the absolute limit. So Friday was a pretty boring day (thankfully). I set up a makeshift office so I could get some work done, and the boys played video games for pretty much the entire day. I'm not apologizing. We did what we had to do.
Luckily, the loading team arrived in KC that morning, loaded everything up, and Byron was able to get to Lincoln that night. We were finally all together, including Daisy, who rode up with Byron.
Saturday: Bright and early, the moving truck arrived to deliver at our new house.
My dad took the boys to his apartment for the day. Byron and I had a weird day of standing around and watching people do a lot of work, directing traffic, and basically wondering how in the world all this stuff fit into our old tiny house. The crew was done by early afternoon, leaving Byron and I to wander around, not knowing where to start. We got the boys home and decided to call it a day.


Lidia Carvajal, institute coordinator, introduced the 2014 ICRPS in Toluca University. She challenged us to live the Mexico experience and equally important to reflect on this reality – both rural and urban, rich and poor. Tom Johnson, one of the founding members of ICRPS, asked everyone to contribute to the goal of preparing students and reinforcing faculty in their rural research pursuits and careers. Thirty graduate students and 19 faculty were welcomed by a five piece musical ensemble and several university dignitaries to kick off the two week school.


text:
⚠ Version 1.1 of The Plant List has been superseded and should no longer be used.
The new version is available at http://www.worldfloraonline.org/tpl/kew-212661. The new version is enhanced, using more data sources including Taxonomic Expert Networks and will be more frequently updated.
Verbena riparia Raf. ex Small & A.Heller
Verbena riparia Raf. ex Small & A.Heller is a synonym of Verbena officinalis L.
This name is a synonym of Verbena officinalis L. .
The record derives from WCSP (data supplied on 2012-03-26 ) which reports it as a synonym (record 212661) with original publication details: Mem. Torrey Bot. Club 3: 12 1892 .
Full publication details for this name can be found in IPNI: http://ipni.org/urn:lsid:ipni.org:names:263302-2.
This name was in version 1 of The Plant List, record kew-212661.
this name record has changed
names related to this name have changed

redpajama_set_name: RedPajamaCommonCrawl


The Art Gallery of Burlington is proud to present the second AGB Ceramics Residency exhibition featuring the work of 2017/18 resident Karla Rivera. With access to fully equipped studios, the residency allows artists to build their portfolio with diverse projects that support the Gallery's programming. It provides the artist with the opportunity to teach in community and studio programs, and to present new work in a solo exhibition in the RBC Gallery.
Karla Rivera is a ceramic artist born and raised in Mexico City. After some travelling, she moved to Hamilton, Ontario. At this point she started to listen to her artistic voice and got involved in the world of ceramics. In 2015 she got a Ceramics Diploma from Sheridan College in the Craft and Design Program. In 2016 she got the position of Artist in residence in the Art Gallery of Burlington. While this happened she was chosen to participate in the Fusion program Creative Direction.
Rivera's work consists of functional and sculptural ceramics. She is interested in the forms that make the connections between the structures of nature such as the shape of an island, and the emotional states of the human mind trying to interpret and project them.
Image: Karla Rivera, Always Between the Fine Line, 2017.


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Yesterday I wrote about the birth of Jesus Christ. There was a cultural and historical context that doesn't support the way most westerners see this significant event. From this point forward, when I think of Christmas, I won't be thinking of quite stables on a chilly December night because there wasn't room in the local inn. It's not significantly different, but it's meaningful to know how things actually played out. That post was already too long and I had a few more things to day, thus the title of this post.
When spending the day in Bethlehem, I learned a few additional things about the birth of our savior that I'd never hear in a lecture or read in a book. One was a local joke and the other was an interesting bit of trivial information that I'd never heard that foreshadows the work that Christ would do on the cross.
After visiting the the Church of the Nativity, we drove over the "The Shepherds Field" where the shepherds were when the angels appeared to them. At The Shepherds Field, we saw another hillside cave common to this area. It was in this cave where shepherds would bring their flocks in the evenings. The cave gave us a very clear idea of what a shepherd's home might have looked like. It was at this time that our guide told us a little more about this place. The Shepherds Field is in the village of Bayt Sahur. It's currently a Palestinian town of 10,000+ inhabitants. It was likely a very small village on the outskirts of Bethlehem. Here's the thing about Bayt Sahur, they have a legendary reputation for gossip. As many small towns do, word travels fast in Bayt Sahur. The local joke is that the angels appeared to the shepherds in the field at Bayt Sahur because they wanted to be sure that word of Jesus' birth traveled fast. You're not going to find that juicy information from a book.
Here's the other thing we learned. Shepherding in this region that included Bethlehem and Bayt Sahur had a very specific purpose. Lambs born in this region were used exclusively for the temple. Female lambs were used in the temple for peace offerings. The male lambs were used for the morning sacrifices, burnt offerings, and such. However, most lambs born in Bethlehem were destined to become Passover lambs. It's believed that the shepherds in this area were actually shepherd-priests who were charged to care for these very important flocks used for temple service. It was their responsibility to make sure that the lambs were not blemished during birth. You see where this is going?
According to the Mishna, there was a practice used to protect newborn lambs who tend to thrash around when first born. The shepherds would wrap the newborn lambs in swaddling clothes for their protection. These lambs were destined for sacrifice and it was their job to prepare them for what they would eventually do.
Is it possible that this announcement had special meaning to these shepherd-priests? Was the location, events, and announcement of his birth intentionally tied to what Jesus would do for mankind? No one knows for sure, but it feels like a bigger story is being written in a beautiful and purposeful way. Jesus was our sacrificial lamb without blemish, the hope and joy of our existance.
NextWas Jesus Really a Carpenter?


Stellar Lumens has been enjoying a ton of success as of late. XLM's own blockchain makes money transfers safe, quick and efficient. It also makes it so reliable banks and even financial institutions can invest in this as well. They are all jumping on the wagon and this is creating a ton of demand. With all of this is happening, more and more investors are choosing to follow and this can only mean good things for the currency.
XLM has a market cap of well over $8 billion and this happened at the time this article hit the press. The coin is valued at $0.43 at the moment and the cryptocurrency market has experienced a huge 15.44% surge. On top of this, all of this movement has happened over the last 7 days and it is also ranked as being number 8 on the top-rated cryptocurrency board. Stellar Lumens is now being supported by CEX.IO and the benefits that come with this are truly endless. The price has increased by a ton recently and they have also benefited from the fact that the coin has gone on to experience traction through various messaging apps as well. This coin will be the first altcoin to really benefit from money transfers and it will also benefit from a ton of instant messaging apps as well.
Stellar Lumens is about to join Lobstr which is a high-tech trading platform. When you look at this platform you will find that it can easily be used to trade with the touch of a button. You can download it for IOS and you can also download it for Android as well if this is something that you are interested in. Stellar Lumens does not actually grow through earnings, instead it grows through inflation. This means that the whole thing would progress very quickly if they did happen to gain traction. The firm have proclaimed that over 100,000 new coins would be handed out to users every single week as a result and that there are not going to be any charges from this either.
Of course, apart from Stellar, NEO is also on the rise. NEO was actually developed in China and it stands to be one of the fastest growing cryptocurrencies out there. It is becoming a true contender. NEO is said to have a blockchain that is very similar to Ethereum and it is also referred to as being the Chinese Ethereum from time to time as well. NEO's own value has been surging for quite some time and this has been the case since early February. It has reached the highest bank rank it has ever seen and a lot of people are looking forward to seeing its continued success. Of course, it needs to be given the right opportunity for this to happen and a lot of people are speculating that this will happen.
NEO is valued at $86.16 at the moment and it is 11th on the ranking system. On top of this, it has a market cap of $5 billion. It has also had a surge of 16.91% in the last week. Stellar Lumens and NEO are both on the rise and a lot of people are stating that they are going to be in the top 5 in no time at all. This is huge news to say the least.


text:
import nose.tools as ntools
import unittest

from smqtk.utils.configurable_interface import Configurable

__author__ = "paul.tunison@kitware.com"

class TestConfigurablePluginInterface (unittest.TestCase):

    def test_default_config(self):
        class T1 (Configurable):
            def __init__(self, a, b, cat):
                pass
        ntools.assert_equal(
            T1.get_default_config(),
            {'a': None, 'b': None, 'cat': None}
        )

        # star stuff shouldn't change anything
        class T2 (Configurable):
            def __init__(self, a, b, cat, *args, **kwargs):
                pass
        ntools.assert_equal(
            T2.get_default_config(),
            {'a': None, 'b': None, 'cat': None}
        )

    def test_default_config_with_default_values(self):
        class T1 (Configurable):
            def __init__(self, a, b, c=0, d='foobar'):
                pass
        ntools.assert_equal(
            T1.get_default_config(),
            {'a': None, 'b': None, 'c': 0, 'd': 'foobar'}
        )

        # star stuff shouldn't change anything
        class T2 (Configurable):
            def __init__(self, a, b, c=0, d='foobar', *args, **kwargs):
                pass
        ntools.assert_equal(
            T2.get_default_config(),
            {'a': None, 'b': None, 'c': 0, 'd': 'foobar'}
        )

class TestAlgo1 (Configurable):

    def __init__(self, foo=1, bar='baz'):
        self.foo = foo
        self.bar = bar

    def __eq__(self, other):
        return self.foo == other.foo and self.bar == other.bar

    def __ne__(self, other):
        return not (self == other)

    def get_config(self):
        return {
            'foo': self.foo,
            'bar': self.bar,
        }

class TestAlgo2 (Configurable):
    """
    Semi-standard way to implement nested algorithms.
    Usually, algorithms are associated to a plugin getter method that wraps a
    call to ``smqtk.utils.plugin.get_plugins``, but I'm skipping that for now
    for simplicity.
    """

    @classmethod
    def get_default_config(cls):
        default = super(TestAlgo2, cls).get_default_config()
        # replace ``child`` with config available config
        default['child'] = default['child'].get_config()
        return default

    @classmethod
    def from_config(cls, config):
        config['child'] = TestAlgo1(**config['child'])
        return cls(**config)

    def __init__(self, child=TestAlgo1(), alpha=0.0001, beta='default'):
        # Where child is supposed to be an instance of TestAlgo1
        self.child = child
        self.alpha = alpha
        self.beta = beta

    def __eq__(self, other):
        return (
            self.child == other.child and
            self.alpha == other.alpha and
            self.beta == other.beta
        )

    def get_config(self):
        return {
            'child': self.child.get_config(),
            'alpha': self.alpha,
            'beta': self.beta
        }

class TestConfigurablePluginTestImpl (unittest.TestCase):

    def test_algo1_default(self):
        ntools.assert_equal(
            TestAlgo1.get_default_config(),
            {'foo': 1, 'bar': 'baz'}
        )

    def test_algo2_default(self):
        ntools.assert_equal(
            TestAlgo2.get_default_config(),
            {
                'child': {'foo': 1, 'bar': 'baz'},
                'alpha': 0.0001,
                'beta': 'default'
            }
        )

redpajama_set_name: RedPajamaGithub


With spring on its way, residents of South Jordan, UT and other nearby communities will gradually stop using their heaters and start using their air conditioners. We recommend that homeowners schedule an air conditioning maintenance session with a trained technician sometime in the next few months, before the weather gets too hot. Maintenance sessions allow a technician to check for any potential repair issues that may be growing, as well as cleaning off the dust, lubricating moving parts and tightening loose bolts. What are the benefits of such attention? We've listed a few of them below.
When you stop using your air conditioner for the winter, that doesn't mean that potential trouble stops as well. Dust coating key components can increase the strain on other parts of the system, resulting in overheating. Refrigerant leaks may have been taking place for months without detection, leaving your system unable to cool the house efficiently. And this precludes more serious problems such as frayed fan belts and clogged filters. Getting those issues taken care of is priority one once the warm weather starts. A maintenance session can do so in one fell swoop ensuring that your system is ready to go as soon as you need it.
Even if your system doesn't have any problems that have developed over the long winter, you want it to perform as efficiently as possible. That way, you can enjoy cool air throughout the summer without having to pay any more for it than necessary, as well as reducing the risk of a more serious breakdown over the hot summer months. When applied over time, regular maintenance sessions can even extend the life of your air conditioner, delaying the day when you'll have to pay to install a new one.
Call At Your Service today for quality air conditioning maintenance.


text:
Petition of British Waterways Board
Under Scottish court procedure the employer's petition for judicial review based on its contention that there was no 'dispute' which could properly be referred to adjudication failed because whilst it was arguable that there was no dispute, the balance of convenience favoured the adjudication going ahead
This case concerned Scottish court procedure. The employer brought a petition for judicial review. The main issue for determination was whether a dispute existed between the parties which could properly be referred to adjudication at the time of the hearing of the petition. The employer maintained that there was no ?dispute? within the meaning of section 108 of the Construction Act 1996 having regard to the terms of the contract. It was common ground that the approach to be adopted by the court where the parties sought interim orders in a petition for judicial review. This was that the court had to be satisfied before granting any such interim orders that there was a case to try. If the employer got over that hurdle, the parties then had to make representations about where the balance of convenience lay and the court had to make a decision in this connection. Lord McCluskey held that the employer had got over the first hurdle in that there was indeed an issue to be tried as to whether there was a ?dispute? arising out of the contract. However, the judge went on to hold that the balance of convenience nevertheless favoured the refusal of the motions placed before the court. Both the Construction Act and contractual dispute resolution procedure envisaged the desirability of proceeding to a speedy resolution of matters in issue without delay. The parties in the instant case had had some months to investigate and consider their respective positions and to research matters. The extra cost of putting these matters in an appropriate form before an adjudicator was unlikely to be very great. In addition it was clear that the parties were unlikely to make use of any additional period of time involved by the petition going ahead given that an agreement had eluded them over the months preceding the issue of the petition. Advice Note In Scotland notwithstanding that it is arguable that there is no ?dispute? capable of being properly referred to adjudication, the courts will not grant an injunction to prevent the referral where the balance of convenience militates against such a referral.
Sara Tonge


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Home 14k Gold Body Jewelry 14kt Yellow Gold White Synthetic Opal Spiral Twister 14 Gauge 7/16"
14kt Yellow Gold White Synthetic Opal Spiral Twister 14 Gauge 7/16"
Quality luxury 14k gold body jewelry made in the USA. Handmade in house by our skilled jewelers; this pieces is made to order and can take from 7 to 10 business days to ship.
Dress up almost any piercing you like with this vibrant yellow gold twister body jewelry. Made with 14k yellow gold, this 11mm horseshoe barbell features two internally threaded white 5mm synthetic opal ends. Spiral jewelry can be used for multiple piercings including your belly button, lip, ear, eyebrow and more! This 14k gold circular ring is a great multipurpose choice!


There is something very special happening in the Australian jazz scene at the moment and it's called the ishs/Allen Project. On a freezing Wednesday night, the last thing you expect is a packed out Melbourne CBD jazz club, but that is exactly what happened. The ishs/Allen Project's show was standing room only with all seated tickets sold out prior to the night. The vibe of the room was opposite to that of the dreary night outside. The wine was flowing, the conversation babbling and the excitement rising as it hit performance time.
Opening with A Place in the World the ishs/Allen Project showed the audience that they intended to give the patrons exactly what they hoped for – a contemporary jazz night to be remembered. The passion of these musicians is evident in the way they put their heart into each performance.
Trumpeter Ee Shan Pang proved that a small frame doesn't equate to lung capacity as she led an improvised lead break that captured the entire audience. Ade Ishs launches himself out of his piano chair, never missing a single keystroke. Paul Bonnington gracefully creates depth with his stunning upright bass. Finally, Chelsea Allen has never looked happier than she does striking the drums with a refined control.
The second track Welcome Spring is a complete delight. A frenetic yet controlled number that really captures the essence of a spring morning. The crowd loves it and so does the entire band. What is great about the music created by this team is that each note resonates in each of them and in turn the listener. Ade Ishs ability to create an amazing and full sounds with the piano is on display all night throughout each track. The personal connections that they seems to have with each song really helps to create less of a musical performance and more of a complete story.
The addition of new member Ben Nieuwkerk on saxophone, flute and clarinet has added a whole new level to the music this group provides. After having listened to their album for a few months, I was certainly keen to see how they would fit these new instruments into the compositions. The flawless addition of Nieuwkerk has added a stunning new dimension to the playing of the group, each song he contributes to have another layer of meaning otherwise unheard in the previous recordings.
Each song performed on the night differed slightly to the original recording, exactly as jazz should. With subtle eye catches and head nods, Ade Ishs controls the show with ease. No musician cuts off the other and each respects the beginning and end of all sections. The highlights of the night would have to be the beautiful Fragments of Truth and the always amazing Little Flower. As well as Ade Ishs playfully plugging the album in the talk breaks.
This band is taking the contemporary jazz scene by storm. Without even beginning their performance the Paris Cat Jazz Club had offered them another show. This comes as no surprise seeing as the room was full and the music is amazing. The ishs/Allen Project has the ability to bring new listeners into the world of jazz and unite them with veteran lovers. With drum solos that sound like they belong in a rock group and killer saxophone breaks that make you wish you could play, the ishs/Allen Project are making a huge mark in the jazz world.


text:
American economists share 2020 Nobel Prize in Economics
The 2020 Nobel Prize in Economics was awarded to American economists, Paul R. Milgrom and Robert B. Wilson. -- Source: IANS
Stockholm, Oct 12 (IANS) The 2020 Nobel Prize in Economics was on Monday awarded to American economists, Paul R. Milgrom and Robert B. Wilson "for improvements to auction theory and inventions of new auction formats".
According to the Royal Swedish Academy of Science, Wilson has awarded this year's Prize in Economic Sciences as he "showed why rational bidders tend to place bids below their own best estimate of the common value: they are worried about the winner's curse – that is, about paying too much and losing out".
Meanwhile, Milgrom "formulated a more general theory of auctions that not only allows common values, but also private values that vary from bidder to bidder".
Milgrom and Wilson are both from Stanford University.
"This year's Laureates in Economic Sciences started out with fundamental theory and later used their results in practical applications, which have spread globally. Their discoveries are of great benefit to society," says Peter Fredriksson, chair of the Prize Committee.
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Project Description: Two level retail centre. Lettable area 9,200m2, air-conditioned. Lower ground level of 2,000m2 retail plus 200 cars under cover, linked to upper ground level with escalators and lift. Fifteen tenancies.
Client expectations were very clear that as part of the Project Management Role, the project was to be delivered in a way that ensured that the client was not at risk and the target development profit was achieved.


Are you checking the same sites almost too regularly, hoping for an update? Are you posting queries to message boards and other sites, hoping to find something or get a helpful reply? Consider changing your approach or spending less time on the Internet or more time on different sites.
My Ancestry.com subscription lapsed and eventually I will renew it. But now that I don't have 24/7 access to it, I am getting back into records I had ignored for too long and even reviewing my files. And when I do have access to Ancestry.com I make better use of it and am more efficient because I know I don't have it constantly. And frankly some days I spent too much time "randomly" searching on Ancestry and not enough time really researching.


The Infusion Framework is designed to support highly flexible aggregation of reusable components. The Inversion of Control (IoC) system provides the ability for reusable components to pull dependencies from the environment rather than having to push them in initialisers. Inverting control this way allows users of the framework and components to customize implementations by plugging in alternative subcomponents, without having to modify the parent component code.
This component creator function initializes three subcomponents. Each initialization requires a call to fluid.initSubcomponent() with the specific parameters that the subcomponent implementation requires (the array of parameters is the third argument to fluid.initSubcomponent()). The second argument to fluid.initSubcomponent() is the string name of the subcomponent, as specified in the defaults (not necessarily the actual function name).
The fluid.defaults() call declares the default function to use for the subcomponents, by name. Users can override these defaults by specifying a different function name, but the arguments to the customized replacement must be the same, or the user will have to modify the code that calls fluid.initSubcomponent() for that subcomponent.
With IoC, the component creator function does not initialize each subcomponent individually: fluid.initDependents() initializes anything that is defined in the components section of the defaults provided to fluid.defaults().
In the component defaults, the types of components to use for the subcomponents are defined inside a property called components. The fluid.initDependents() will look inside this property for the list of dependents to initialize.
The values for the type properties may be function names, but this is not necessary. The function to use for the types specified, as well as their arguments, are specified through fluid.demands(), shown below.
* Default options for the component with autoInit grade.
With autoInit grade, the component creator function will be generated from component defaults. Any code present in the old style creator function can then be distributed into appropriate lifecycle functions such as preInitFunction, postInitFunction and finalInitFunction.
Additional calls to fluid.demands() can be used to demand different arguments, or even functions, in different contexts. This example shows different demands when the subcomponents are being used by myComponent in a test environment. Test data can be provided instead of actual data, if desired. The third subcomponent is demanding a completely different implementation.
These additional demands specification can be made in a different file, if desired. For example, demands specific to a testing environment can be placed in the test files.


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The closer Britain gets to Brexit, the closer it gets to recession
Apr. 29, 2018, 7:16 AM
Homeless and unemployed people shelter from the cold in a doorway in Hull, November 3, 2017.
REUTERS/Russell Boyce
UK GDP growth was just 0.1% in Q1, and Britain is just 11 months away from Brexit.
The housing market is crashing, and Brits are feeling poorer.
They've slowed down their consumer spending too.
Suddenly, this whole Brexit thing is not looking so rosy.
LONDON — The closer Britain gets to Brexit, the closer the country gets to a recession.
UK GDP growth was just 0.1% quarter-on-quarter in Q1, the government reported on Friday. With the March 2019 Brexit deadline now less than a year away, that's "near stagnation," according to economist Chris Williamson of IHS Markit. Over the last 12 months, "The economy was just 1.2% larger than a year ago, the weakest performance for nearly six years," he says.
You can see from this chart that economic growth in the UK (the black line) has been in decline for a while. The EU Referendum did not halt that slowdown.
Pantheon Macroeconomics
Britons are suddenly feeling much poorer than they were a year or two ago. House price growth is declining. The property market is dangerously close to entering an actual contraction. British people can no longer rely on their houses to add significantly to their wealth.
More worryingly, the forward-looking index of mortgage approvals and new buyer enquiries has collapsed. People don't want to buy houses if they think the value of those houses is going to go down.
It's not just about houses. Consumers generally are spending less. Consumer spending and retail sales are two of the main drivers of economic growth. And yet they are in a near-slump, with growth somewhere around 0%.
Consumers have become more worried about the future. Their "confidence" in their own financial situation and the economy generally is zero, at best, and sharply negative at worst, according to ESI data.
Few economists are predicting an official recession — two consecutive quarters of contraction — right now, even with growth at near-zero. But consumers are behaving as if they are about to go through hard times. Consumer confidence is in decline. Their response has been to increase their intention to save money.
These declines have all come at the same time as a 7-point collapse in support for Brexit, as tracked by YouGov (and monitored in this chart by analyst Samuel Tombs of Pantheon Macroeconomics). There has not been a majority in favour of Brexit since May of last year.
Clearly, delinking Britain from its largest and richest free-trade neighbour will have negative economic consequences. After the 2016 referendum, the economy got a short-term boost as the pound was devalued and exports went up. But the sugar-rush has now gone. Businesses are making long-term decisions on where to invest, where to create jobs. And as Koji Tsuruoka, the Japanese ambassador said recently, it won't be the UK if Britain doesn't stay closely aligned with the Single Market and the customs union: "One thing I can say for certain, based on fact, is that the companies operating today in the UK are not expanding their investment in the UK today."
"This is the best gateway to Europe," he said last week. "If that is in danger, if that is no longer sustainable, of course they will have to look at what they will have to do best. The existing arrangement for the single market is a total frictionless trade."
Predictably, the economy is already responding. The closer we get to Brexit, the worse the picture looks.
This column does not necessarily reflect the opinion of Business Insider.
This is an opinion column. The thoughts expressed are those of the author(s).
SEE ALSO: UK 'underemployment' is worse now than during the financial crisis of 2008
More: Op-Ed Opinion UK GDP Brexit


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Emgwenya (Waterval Boven)
Emgwenya
Emgwenya , Emgwenya (Waterval Boven), Mpumalanga
Waterval Boven NZASM Historic Tunnel
Krugerhof
Five Arch Bridge
Adam's Calendar
Elangeni Hiking Trail
Bermanzi Trail
Num Num Hiking Trail
Horse Trails
Stone Circle Museum
Fishing & Birding
Rocky Drift Nature Reserve
Elands River Falls
Drakenzicht The Mountains Golf Course
Emgwenya receives approximately 660 mm of rain annually with most rainfall occurring during Summer.
Summer months, November to March will have average temperatures of between 14˚C and 24˚C.
Winter months, May to August will have average temperatures of between 3˚C and 16˚C.
There are daily flights into Lanseria Airport, approximately 283 km's away along the N4 and O R Tambo International Airport, approximately 244 km's away via the N4 and N12. Car hire facilities are available at the Airport.
The Dutch railroad company, NZASM, established the town as a supply depot while constructing the Eastern Line Railway, a railway link between Pretoria and Komatipoort in the late 1800s. The Transvaal Republic acquired about 78 hectares of the farm Doornhoek, lying on either side of the line.
Waterval Boven, means 'above the waterfall' in Dutch and it received its name due to its location on the fringe of an escarpment in the Drakensberg Mountains which is above the 75 meter high Elands Falls. Its sister town, Waterval Onder, 'under the waterfall', lies at the base of the escarpment.
The cog wheel rail ascending the slopes of the mountain between Waterval Onder and the town is the only one of its kind in Africa, and a depot for the cog wheel locomotives was established at Waterval Boven. The town was administered by the railways until 1946, when it was transferred to a health committee.
2006 marked the 67th year since the historic train disaster where 63 Mozambican labourers died in a train accident in the early hours of the morning of Wednesday, 16 November 1952. This is a tragedy never to be forgotten in history of Waterval Boven.


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WSU professor wins Alfred P. Sloan Foundation grant for work to assist the visually impaired
Jan. 20, 2022 — The Alfred P. Sloan Foundation has awarded a grant of $243,922 to a Wichita State University researcher for his work on an app that will allow people who are visually impaired to read comic books, graphic novels and other digitized graphic materials on their devices.
Molecular Diagnostics Lab continues to process COVID tests; specimen collection is suspended indefinitely
Jan. 18, 2022 — Wichita State's Molecular Diagnostics Lab (MDL) is open and continues to process thousands of COVID tests with 24-hour results. However, the lab has indefinitely suspended its COVID test collection service.
College of Applied Studies appoints assistant dean for diversity and outreach
Jan. 10, 2022 — Dr. Bobby Berry has been named assistant dean for diversity and outreach for the College of Applied Studies at Wichita State University.
Meet a Shocker: Kennedy Stamm
Dec. 8, 2021— Kennedy Stamm was led to Wichita State because she liked the Wichita School District. Now, she will start her teaching job in August after receiving a degree in elementary education. Stamm is one of more than 1,100 students eligible for fall 2021 graduation.
WSU announces new athletic training graduate degree
Dec. 9, 2021 -- The Department of Human Performance Studies in the College of Applied Studies (CAS) at Wichita State University (WSU) has secured approval for a new graduate-level degree in athletic training. The 62 credit-hour program launches in the summer of 2023.
Meet a Shocker: Joyce Chiam
Dec. 8, 2021— Joyce Chiam, an international student from Malaysia, is earning her degree in industrial engineering with a minor in mathematics from Wichita State. Through the encouragement of her peers, she has learned how to thrive in an academic environment far away from home. Chiam is one of more than 1,100 students eligible for fall 2021 graduation.
Meet a Shocker: Valeria Esparza
Dec. 8, 2021— Valeria Esparza's dream was to attend college as a first-generation student. She is now guaranteed a position to teach elementary education as her future job following graduation. Esparza is one of more than 1,100 students eligible for fall 2021 graduation.
Wichita State launches university-wide Diversity, Equity and Inclusion Plan
Dec. 8, 2021 — Wichita State University's Diversity, Equity and Inclusion Plan (DEI) includes efforts to promote student success, increase sponsored research funding for diversity and inclusive excellence, and empower the campus community to create a culture and experience that meets its ever-changing needs.
Henrion Hall renovations improve sculpture and foundry areas for art students
Dec. 8, 2021 - The second phase of renovations is close to complete on Wichita State's Henrion Hall, the 100-year-old building that houses WSU's studio arts. This recent renovation affects the first-floor north side of the building, where the sculpture department conducts most of its casting processes. Updates include new ventilation and air conditioning, as well as improved accessibility and functionality of workspaces.
Meet a Shocker: Merry Kirkpatrick
Dec. 8, 2021— Merry Kirkpatrick learned how to balance family life and school while earning a degree in the early childhood unified program. She plans to continue working at WSU's Childhood Development Center following graduation. Kirkpatrick is one of more than 1,100 students eligible for fall 2021 graduation.
Meet a Shocker: Lysel Bender
Dec. 8, 2021 — Lysel Bender dreams of becoming a writer and a publisher after receiving a double major in English literature and creative writing. Bender is one of more than 1,100 students eligible for fall 2021 graduation.
College of Health Professions begins expansion of robotic-based clinical simulation technology
Dec. 7, 2021 – The College of Health Professions (CHP) has initiated a major expansion to the its clinical simulation capabilities. Students across the CHP's clinical degree programs will have increased exposure to high-tech robotic simulated patients in preparation for treating humans.
Applied learning abounds within Wichita State's digital twin program
Dec. 7, 2021 — Since its inception, the National Institute for Aviation Research's digital twin program has been rife with opportunities to progress research, digital transformation, engineering technology and sustainability efforts. It's also been an important career steppingstone and training ground for more than 250 Wichita State University students, who have gained valuable applied learning experiences while working on the project.
WSU announces new esports director
Dec. 7, 2021 — The College of Applied Studies at Wichita State University announced today that Travis Yang has been hired as the new director of varsity esports.
Meet a Shocker: Megan Schmidt
December 6, 2021 — From being a mom of five to becoming a labor and delivery nurse. How does Megan Schmidt do it all? Schmidt is one of more than 1,100 students eligible for fall 2021 graduation.
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A front-runner for best American film of the year.
ERIC HYNES, VILLAGE VOICE
Stunning! Moving and totally engrossing.
SIMON ABRAMS, INDIEWIRE
Easily the finest dramatic film I saw at Sundance this year.
ANDREW O'HEHIR, SALON
Forget Brokeback Mountain.
This is the most heartbreaking gay love story of our times.
DAN HECHING, NEXT MAGAZINE
Thure Lindhardt
Zachary Booth
a film by Ira Sachs
Art & Autobiography
Avery Willard
Our Man in Tribeca
Production Diary
Interview with Jonathan Caouette by Kyle Tidd
Jonathan Caouette is a filmmaker from Texas. His first film, Tarnation, debuted in 2003. In Tarnation Caouette incorporated over twenty years of footage to tell the story of his growing up and his relationship with his mother, Renee Leblanc. The film was executive produced by Gus Van Sant and John Cameron Mitchell. He also directed the 2009 documentary All Tomorrow's Parties, on the British music festival of the same name, and the experimental short film All Flowers In Time, starring Chloë Sevigny. His third film, Walk Away Renee, debuted at Cannes Film Festival in 2011. Walk Away Renee conveys the story of the voyage Jonathan and his mother make to move her from Texas to New York City, where Jonathan has lived for many years. The film begins its New York theatrical run tomorrow, November 30th, at IFC Center.
Kyle Tidd: Hi Jonathan! Thanks for agreeing to do this interview. This was my side of our imaginary conversation, feel free to respond however you want, it can be totally unrelated, as you please.
Jonathan Caouette: Oh thank you, I am more concerned about passing out at the moment…I'm on pain medication from a fall last week, I'm waiting right now for a lot of test results to come back…I hope it's nothing too bad…I just turned 40 and had to cancel my celebration plans and have made two doctor's visits and two trips to the ER just in time for the opening of Walk Away Renee.
KT: Whoa, I hope everything's ok! I'm only going to ask you a few questions then you should rest. Is there a connection between the title of the new movie and the 1966 song by The Left Banke?
JC: Yes, The Left Banke is one of my favorite bands of all time. My mother turned me on to Walk Away Renee (the song) and Pretty Ballerina when I was a baby. Also, if it weren't for The Left Banke there would be no Belle and Sebastian…
KT: Would you say Walk Away Renee is to Tarnation kind of like what Amnesiac was to Kid A, i.e. material salvaged from the first work that elaborates further on the relationship set up between you and your mother in Tarnation?
JC: I love that analogy, yes it is! Well, actually in a nutshell—and I'm half joking about this—but for me, in a sense the film essentially feels like it could be an opulent DVD extra, an easter egg, on disc two, for a 20 year DVD (or whatever the format will be in 2024) anniversary of Tarnation…that I somehow traveled forward in time and stole it from myself just before I put it on that disc two DVD and then came back and just, well, presented it now in 2012.
KT: You've mentioned H.G. Wells' The Time Machine before, and I've also heard you're working on a film about time travel.
JC: I kid you not, and I'm not trying to sound like James Franco or anything, but I have seven projects in development, all of which are going to come down the pipeline as it were in beautiful even-keeled paced succession. One of these is in fact a narrative film I'm writing and directing about time travel.
KT: Can you talk a little more about your interest in time travel?
JC: Yes. Long story short, I wish I had a time machine so that I could leave this time and go back to, I don't know, 1950 and live until 1986. I love the subject and I am really interested in exploring it in a way that I don't necessarily think has been done before; the idea of completely personalizing that story really excites me.
KT: And the relationship between time travel and cinema?
JC: Well, I feel a bit like John Cusack in High Fidelity. I associate specific memories and directly correlate the memories to music and films that I had seen during particular times in my life.
KT: I realize that Walk Away Renee was made in relation to certain practical considerations (the need to move your mother to New York from Texas), but it my understanding that you have always wanted to make a classic roadtrip film. Would you say a roadtrip is like time travel in some ways? Your mother moved to New York in part because she was receiving inadequate medical care in Texas. There seems to be an undercurrent in your work between cinema, time travel, and story-telling. Could you talk about that?
JC: YES, but if I answer that all the way right now honestly and detailed I would be giving away the plot of the film, which I can't do right now.
KT: I understand. Apparently there was a segment cut from the film that had to do with a Wilhelm Reich cult group called the Cloudbusters. Are you a Kate Bush fan?
JC: Huge, huge huge fan. She is like my demi-goddess. I grew up listening to the likes of Kate Bush, Lene Lovich, Nina Hagen, Le Rita Mitsouko, etc.
KT: Why were the Cloudbusters cut from the film?
JC: That scene, coupled with a lot of other scenes coupled with a structure that I could not properly and comfortably digest, was screened at Cannes. The Cannes version of Walk Away Renee is an entire book in itself. For me it was the right film but the wrong version at the wrong time at the right festival. I was so unbelievable gobsmacked grateful beyond words to have the opportunity to show the film as the work in progress at Cannes. But that version became re-tooled about three times just after that showing. The new and final version will be present at IFC this Friday, November 30th. My family and I will be at the last showing of the night. I'll be on crutches!
Art and Autobiography
Walk Away Renee
The Art Market's Dead Reckoning by Ioannis Pappos
It was brunch time on a sunny Saturday in New York's West Village. Julian Schnabel, the celebrated artist and filmmaker, was holding court at Sant Ambroeus' main table. The larger than life New York artist was surrounded by seven friends, most of whom cowed by Schnabel's towering personality. Dressed in one of his signature pajamas outfits, he introduced "Paolo!," his "favorite waiter," to the crammed table. Rula Jebreal, the stunning Italo-Palestinian journalist (and Schnabel's life partner), was squeezed to his left, and folding chairs were added so Lou Reed and Laurie Anderson could fit in. Power-agent Bryan Lourd stopped by, dangling a baby over eggs crostino so the artist could cradle the newborn for a second or two. Downtown fixtures gave quick greetings while the artist nodded behind his sunglasses. Schnabel "had" the room. Nothing could upstage him.
Airtime
Henry Kravis
John Elderfield
Marie-Josee Kravis
vyclone
Interview with Famke Janssen by Jason Klorfein
BRINGING UP BOBBY, written and directed by Famke Janssen, opens in New York on Friday, September 28 at the Beekman Theatre. Janssen will be in attendance for Q&A at Friday and Saturday screenings.
Whether she's an ensemble player in a big-budget genre film (Goldeneye, X-Men), or the lead in an Ameri-indie (Love & Sex, Turn the River), Famke Janssen carries an aura of admirable self-sufficiency. Her exotic looks means that she can hold your attention even when's placed at the margins of the frame. Orgasming to the sounds of machine gun as an assassin who kills men with her thighs in Goldeneye, or giggling at the idiocy of lover Kenneth Branagh, Celebrity (1998), she always seems game – even when the movie may have forgotten what to do with her.
While her leading roles feel like concepts derived from diva worship, Janssen is winningly, refreshingly opaque. In Turn the River (2007), she plays a working-class pool-shark, determined to win back custody of her son. The movie sounds like boilerplate for a de-glammed actor vehicle, but Janssen doesn't pry for empathy. Her coolness results in a physical and emotional awkwardness that is true to the character.
A Dutch-born former model and New Yorker since the 80's, Janssen debuted on-screen in the mid 90's. In a fickle industry, genre films tend to be the sanctuary to Euro-goddesses. But while Taken 2 (opening October 5) might pay the mortgage, Janssen has written and directed her first feature, Bringing Up Bobby. Ukranian- Olive (Milla Jovovich) is a con artist and single-mother raising her young son in Oklahoma. But when one of her schemes results in jail time, she has to decide whether to fight for her son, or let him try to live a normal life with a wealthy couple played by Marcia Cross and Bill Pullman.
Bringing Up Bobby
May the Changes Keep Coming: An Interview with Peter Quinn by Daniel Quinn
Peter Quinn was a speechwriter at Time Warner and also wrote for New York Governors Carey and Cuomo. Quinn is an Irish-American historian, an expert on all things New York and an accomplished novelist. He also happens to be my father.
He and my mother were both born and raised in The Bronx and our family has deep artistic, political and personal ties to this city. I asked my father some questions in order to more clearly understand his relationship to New York and the city's continuing evolution.
peter quinn
Carlos by Ariel Kavoussi
Carlos consists of three vignettes, three windows into the life of a struggling art student. I made the film as my final video project for a college class on narrative filmmaking. The film stars my best friend Carlos Diaz, and my grandmother, Margaret Kavoussi. Carlos is entirely autobiographical – I majored in Studio Art at a small, isolated liberal arts college. I spent a great deal of time there frustrated, insecure, and alone, typically in my studio, and there were days when the only person I'd speak to would be via the phone or internet. Carlos is my attempt to show the beauty of a nuanced "artist" life.
ariel kavoussi
Kiss and Tell: Marialy Rivas and Alicia Rodriguez by Alix Diaconis
Marialy Rivas' debut film Young and Wild (2012) premiered at Sundance and received the World Cinema Screenwriting Award. We got the opportunity to talk with Marialy Rivas and Alicia Rodriguez, the lead actor from Young and Wild, about their experiences at Sundance, their upbringings in Chile, and their times in New York. Marialy and Alicia will also be at the NewFest Closing Night screening of Young and Wild, tonight on July 31st.
Daniela (Alicia Rodriguez) wakes up on an anonymous naked man after a wild night. First, she masturbates. Then, she presses ignore on her cell phone to reject her mother's third consecutive call. And finally, she rushes to her Evangelical church service. Marialy Rivas' Sundance Award Winning film, YOUNG AND WILD (2012), depicts the life of a Chilean teenager caught between her Evangelical upbringing and hormone-driven, blossoming body.
Alicia Rodriguez
Marialy Rivas
Francophrenia – Shots are Thoughts by Ioannis Pappos
In quantum labs you can see an object in two different places at once. Yes, at the same time. Laugh, I used to, but quantum physics is a radical science. I studied electrical engineering and was taught Heisenberg's theory that atoms are not things but rather tendencies. Still I can't totally believe that one object can be in more than one place at the same time. This was the first paradox I came across in my adult life, something I re-lived watching Francophrenia (Or Don't Kill Me, I Know Where the Baby Is), an experimental film around James Franco's appearance in a soap opera.
Negative Joy: Keeping it Real by Alix Diaconis
443 PAS is a NYC gallery that exhibits emerging and established artists in Kevin Asbec's interior design firm. Recently they held an event called "Negative Joy", screening video art portraying our sometimes dark lives in a humorous, ridiculous, and maddening light.
I originally went to the "Negative Joy" video art screening at 443 PAS because I saw Shana Moulton and Tim Davis on the list of artists. As often is the case, I was more engaged by the other artists than those whom I had come to see. Animated works by Rao Heidmets, Jacolby Satterwhite, and Monica Cook were the most grotesque, ridiculous and emotionally truthful animations I had ever seen. The videos' humorous animations and absurd story lines (or lack of) juxtaposed with their underlying sense of fear and realism, reminded me of dreams I have when I'm sick. The hallucinatory, illogical worlds in these videos engulfed me enough for me to experience and relate to the otherwise nonsensical worlds. More…
Jared Buckhiester in 1991 by Jared Buckhiester
This week in Art and Autobiography, we're beginning a new feature, asking some of our favorite visual artists to explore the autobiographical nature of their work. First up, New York-based artist Jared Buckhiester, whose drawings and sculptures often recall faded snapshots of awkward teenage moments.
My sculpture "Jared Buckhiester in 1991" was actually made in 2008. At that time, like in my earlier drawings, I was definitely in a place of needing to work things out from my personal history, needing to rewrite it or simply rethink it. For a long time I collected yearbooks from high schools and middle schools I did not go to. They provide an opening for me to an experience that is shared in almost every American, and most human. I could look at the pictures in them for hours. In relation to my work I usually find myself hunting for photographs of the kids that seemed what I would call "unchosen", not necessarily queer but the ones that interested me most usually seemed to be. More…
All Letters Are Queer: Jonathan Kemp on "Twentysix" by Adam Baran
One of the central ideas at the core of Keep The Lights On is that we must be committed to talking about the secret behaviors which we've learned to keep hidden from the world. UK-based author Jonathan Kemp's new book Twentysix is one of the most dynamic illustrations of this idea I've read in some time. The book is a slim yet dense collection of 26 gay sexual encounters told in unsparing detail alongside philosophical observations that try to get to the core of the narrator's pursuit of pleasure. Like Georges Bataille and Jean Genet before him, Kemp's prose is titillating, dark, and honest to its core. I spoke with Kemp this past weekend about his influences and how he created such an involving and unusual piece of writing. More…
Writers on writing
Although Federico Fellini said "All art is autobiographical," not every work of art comes with the headline "Based on a True Story" to help us understand it. This section offers a space for artists from across the creative spectrum to discuss the processes involved in making work that stems from one's own experience.
Keep the Lights On is a chronicle of life, love and art in New York City and beyond, inspired by the new film by award-winning director Ira Sachs (Forty Shades of Blue, Married Life, The Delta, Last Address), currently in production.
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In which Frishberg and Lambdin present Presumptive Design in a webinar format, specifically in the context of Agile, comparing and contrasting it to Lean UX.
In which I suggest that UX's responsibility for delivering emotional experiences may be more than most organizations are ready for.
In which I suggest we should fail intelligently as early as possible to avoid costly failures down the road.


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FINNLO's dumbbell set is ideal for entry-level body building. Shoulder shrugs, side lifts and intensive arm exercises - you can do it all with this well-priced entry-level set! The plates are secured with a star-shaped collar for a perfect lock.


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Q: Grails: Groovy error reported on tomcat plugin after creating a new project I am using SpringSource Tool Suite
Version: 2.3.3.CI-R5608-B54
Build Id: 201008210801
with Java 1.6.0.u21 & Grails 1.3.5
I created a new grails plugin project and after the process was completed, STS reported problem as below. I had this problem before when creating grails project but usually got fixed if I do grails clean or project clean. But this time this problem is not getting fixed!
Description Resource    Path    Location    Type Groovy:The class java.lang.Class refers to the class java.lang.Class and uses 1 parameters, but the referred class takes no parameters TomcatServer.groovy /SampleGrails/tomcat-1.3.5-src-groovy/org/grails/tomcat line 439    Java Problem

What can be done to fix this problem?
Thank You.
Jay Chandran

A: I can't reproduce this in STS 2.5.0M3 so perhaps it's an issue that's already been fixed. You can install 2.5 from http://www.springsource.com/products/springsource-google-download. It's technically a milestone release but very stable and has a lot more features (esp Groovy and Grails) - I haven't had any issues using it.
You might also try the mailing list at eclipse-plugin-user@groovy.codehaus.org

redpajama_set_name: RedPajamaStackExchange


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Wednesday 22 January 2020 - 2:38:02 pm
International Relations UAE Humanitarian Aid Culture, Heritage & Tourism Women Empowerment Transport & Infrastructure Environment & Sustainability Expo 2020 Dubai Events Decrees Kids' Bulletin Youth Local News
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2020: Towards the next 50
Expo 2020 News
Suqia highlights Global Water Award's objectives
DUBAI,16th August 2019 (WAM) - Saeed Mohammed Al Tayer, MD and CEO of Dubai Electricity and Water Authority, DEWA, and Chairman of the Board of Trustees of the UAE Water Aid Foundation (Suqia), met with Low Pit Chen, Consul-General of the Republic of Singapore in Dubai.
The meeting focused on cooperation between Singapore and Suqia on water and innovation, as well as the Mohammed bin Rashid Al Maktoum Global Water Award launched by His Highness Sheikh Mohammed bin Rashid Al Maktoum, Vice President, Prime Minister and Ruler of Dubai, to encourage research centres, institutes, and innovators from all over the world to develop sustainable and innovative renewable-energy solutions using solar energy to address the problem of drinking water scarcity.
The award is overseen by Suqia under the umbrella of the Mohammed Bin Rashid Al Maktoum Global Initiatives, MBRGI.
Suqia is keen to provide clean water by conducting research to develop innovative and sustainable technology solutions to help millions of people suffering from scarcity and water pollution around the world, Al Tayer noted.
He highlighted the fact that in 2018, over nine million people in 34 countries benefitted from Suqia's projects to provide clean drinking water. Under the umbrella of the MBRGI, Suqia is supporting the UAE's humanitarian efforts and continuing the legacy of the late Sheikh Zayed bin Sultan Al Nahyan, who established the principles of humanitarianism in the UAE as a way of life. The wise leadership follows the same path in the service of humanity.
"Suqia continues its efforts to achieve the goals set by the Mohammed Bin Rashid Al Maktoum Global Initiatives to combat poverty and disease by providing safe drinking water to communities suffering from water scarcity and pollution, in cooperation with partners from governments, public and private institutions, and individuals to implement projects and initiatives," Al Tayer said.
Suqia aims to contribute to finding sustainable, innovative global water scarcity and pollution solutions through research and projects, using solar power to provide clean water. It also seeks to explore ways to purify water using solar power to meet the increasing demand and contribute to sustainable development.
The Singaporean Consul-General praised Suqia's efforts and said they were looking forward to cooperating on projects that would serve communities by providing safe drinking water.
WAM/Hassan Bashir
Emirates News Agency
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Academic Integrity - information and resources for students and faculty members.
Student Policies and Procedures - Faculty policies on appeals, clinical placements and professional unsuitability.
Student Resources - where to find help and support on campus.


1 out of 4 patients receives the wrong diagnosis. The results of that wrong diagnosis could cause you to receive inappropriate treatment and could result in a lifelong injury or even death. Misdiagnoses can occur in a variety of ways, including inappropriately ordered lab work, improper charting, wrong medical diagnosis, and failure to report results. Luckily, there are ways you can avoid a misdiagnosis and potentially save your life.
The main way to avoid a misdiagnosis is to locate the right doctor for your problem. While a general practitioner is best for normal ailments, when you have a serious or chronic illness, it is wise to speak to a specialist. A doctor who specializes in your symptoms and your illness can alert you to any mistakes and can avoid misdiagnoses.
Seattle patients need to speak up when they are sick. If you feel you are not being taken care of or if you have questions concerning your illness, it is always a good idea to voice your concerns. If you feel that you are not being heard or that your concerns are not being addressed, ask another physician or nurse until you receive the explanation or the treatment you need. If your doctor orders tests or lab work to be done, be sure to ask for an explanation of those tests and the reason for ordering them. Also, call back when the results are in to be sure your results are appropriately reported.
When you receive a diagnosis, it is always wise to have that diagnosis confirmed by another doctor. This is especially important for critical diagnoses, such as cancer, heart disease, or chronic debilitating disorders. Second opinions also offer you the chance to ask more questions, understand the disease process a bit better, and double check the results of lab work, EKGs, and MRIs.
If you received a misdiagnosis and this caused you to receive inappropriate treatment or caused a lifelong chronic disability, it is important to consult with a Seattle medical malpractice attorney immediately. Your attorney will be able to review your case thoroughly to determine if medical malpractice was to blame for your misdiagnosis.
If you or someone you love was injured through the negligence of a physician or medical personnel, you may be eligible for compensation for your injuries. The Seattle medical malpractice attorneys at the Phillips Law Firm can help. Our attorneys have successfully represented individuals in medical malpractice cases in Seattle, Everett, Tacoma, Bellevue, and throughout the State of Washington. To learn more about your legal options, call us at 1-800-708-6000. Our Seattle medical malpractice attorneys are waiting to assist you 24/7, offering a free case evaluation. Remember our no fee promise. If we do not recover anything for you, you do not owe us an attorney fee.


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Morrison missing in action for Eraring power workers
Origin's announcement that it will accelerate closure of Eraring power station to mid 2025 is entirely foreseeable, exposing the Morrison Government's failure to plan for the economic security of the workforce and the community.
"The challenging economics of coal fired power generation have been obvious to anyone who takes a passing interest for years," ETU Assistant National Secretary, Michael Wright said.
"But the Morrison Government has failed to plan for the economic security of workers, their families and their communities. They seem content to throw them to the wolves…
"Scott Morrison and Angus Taylor are simply missing in action, at precisely the time workers and their families need security and support. Twelve coal fired power stations have already closed in the last decade, but Scott Morrison keeps acting like everything is fine. Where is the regional transition program?
"These workers have paid taxes, been active in their community and played by the rules. Now Scott Morrison wants them to wear the cost of a global shift.
"Morrison and Taylor are incompetent and negligent. They have their head in the sand and expect workers to bear the brunt.
"A responsible Government would look at the shift to renewable energy generation and storage and understand that it would shift the economics of the power industry. A responsible Government would be taking the opportunity to invest in the communities that are going to be hit hardest. That's what responsible governments elsewhere have done, why can't Scott Morrison?"
Read the latest media releases from the ETU
Nowhere to go – women's loos continue to disappoint on building sites
Dangerous plan to remove safety checks for electricians must be ruled out
Higher education review needs skills and training sector voices
This article was publised on 17 February 2022.


text:
Edinburgh church unveils stunning two-year renovation
An Edinburgh Church will reopen at the weekend for services following a stunning £1.1 million renovation which has taken two years to complete.
Blackhall St Columba's will reopen this weekend after a two-year renovation.
Blackhall St Columba's, who will be welcoming back members of the congregation into the space for the first time since 2018, will now be fully equipped for 21st century worship.
The ambitious upgrade of the building, which was first built in 1900, includes the removal of pews to create a more flexible space and an entirely refurbished sanctuary.
Despite the scale of the project, the changes were funded entirely by the congregation, with just under half of the cost coming from the sale of a church property and the rest from donations and fundraising.
Rev Fergus Cook, who was ordained and inducted as the parish minister just before lockdown began, said: "The Church of Scotland is looking for church buildings to be well equipped spaces in the right places. "Blackhall St Columba's Parish Church is well located and I firmly believe that due to foresight and the generosity of the congregation in managing this refurbishment of its sanctuary it is now well equipped to fulfil its mission statement: to glorify God, to proclaim Christ, to serve others."
He also paid tribute to the hard work of those involved including the Building For the Future Group, Alan Thomson of Lee Boy Architects and the project manager Fay Stirling.
Rev Fergus Cook was ordained and inducted the day before lockdown
Speaking about reaching the end of the renovation, Ms Stirling explained the ethos behind it.
"There were a few important principles which we wanted to adhere to," she said.
"Firstly we had to be good stewards of the money which had been so generously given and spend it wisely.
"We also wanted to maintain the character of the building."
Despite Coronavirus throwing their plans into "disarray" and inevitably delaying work, Ms Stirling describes the final results as "transformational".
Glass doors provide a welcoming, well-lit entrance, with new underfloor heating added to ensure the building is efficiently heated.
A sophisticated audio-visual system now allows for varied lighting, screens and livestreaming, with elegant and efficient LED lighting added to the nave.
More space has been created for meetings and the church office and vestry has been upgraded.
Churches awarded grants from green recovery fund
Moderator will host first Grasping the Nettle event of the year
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When it comes to finding an RFID wallet for women, there is no better choice than WalletBe. We understand how important it is to find a wallet that matches your style needs as well as keeps your credit card information safe. If you are looking for something new and exciting to keep your money, cards, and identification organized, then this brightly-colored accordion wallet might be just what you need.
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This wallet was made from hand-finished, two-toned Italian Croco Embossed Leather and was designed to fit into even the smallest of purses. With the color selection available, there's no harm in getting more than one! The outer ID pocket will provide the convenience you need to flash your ID, but it also allows for quick and easy removal if you need. However, this wallet also offers a hidden curtain feature to hide your ID while carrying this wallet as a wristlet!
RFID features in a wallet are more important now than ever. Don't let your security and information be at risk. Nowadays, thieves can access your credit card information without ever laying a hand on your wallet. With our RFID women's wallet, you can rest assured that your info is protected everywhere you go. Whether you are flying to a new place or keeping it local, this wallet is a must-have.
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Leo Computers Ltd. was formed in November 1954, as a result of a decision by UK catering business J. Lyons & Co. to use computers in their commercial operations (J. Lyons & Co. operated tea shops from 1887 - 1998).
The company developed a computer, called Lyons Electronic Office (LEO), based on EDSAC, a computer developed in Cambridge. EDSAC was adapted from a machine designed for technical calculations into one suitable for business data processing.
Leo Computers merged with English Electric 1963; later English Electric-Leo then English Electric-Leo Marconi then English Electric Computers; incorporated with International Computers Limited (I.C.L.) in 1968.
LEO I and LEO II used mercury delay line memory; LEO III used ferrite core memory.
The core memory (ST 029038) in Museum Victoria's Collection was purchased from United Trade Sales.


an unusable format, or on outmoded media.
or by transcribing it to a modern media.
Legacy data can be used much more effectively if converted to a modern format and QCed expertly, providing a product immediately ready for assessment.
The image compares the scanned interpreted hard copy on the left, with the vectorised SEG-Y on the right. Note the retention in amplitude and frequency ranges as well as the removal of the interpretation and blemishes, restoring the image back to the data it was created from.
Petroscan's vectorising process retains the amplitude and frequency ranges so often lost by many providers of this service.
Our experience and techniques enable us to vectorise images that clients, and other service providers, might consider unrecoverable.
Petroscan are able to digitise, QC and process well log data of virtually any quality. Our experienced processors and QCers ensure a seamless end product.
Petroscan is able to capture any information presented on a map, shotpoints, geological data, cultural data etc., and export in a variety of industry standard digital formats.
Petroscan utilises an initial assessment of data/media followed by processes designed to improve the versatility of the data, increasing value while ultimately saving cost.
Please contact us for more information or a free trial.
Our experienced team ensure that our clients get the best possible quality and turnaround available. In this Age of Austerity, Petroscan offers a lower cost solution enabling our clients to make informed decisions without breaking the bank.


Since our first Disney concert is already SOLD OUT, we are opening a second one-same day, same location-check the time!
Let's go on an adventure.... with DISNEY MAGIC!
Let us transport you to the sparkling world of DISNEY!


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Singles in Leicester want singles events, singles travel, romantic dining, singles cruises, relationship advice and Leicester nightlife. Looking for local singles and love in Leicester? And so, knowing where and how to meet potential life partners is where Slow Dating can help. We can help you to get off dating apps, swiping right on Tinder and trying to find love on a night out, just by booking on to one of our speed dating in Leicester events.


The NZDUSD pair built on previous session's strong upsurge and climbed to the 0.6700 neighborhood, or five-week tops in the last hour. Where is the pair now headed? GKFX's analysts shared their technical outlook.
2 November, GKFX – The pair on Thursday rallied hard and confirmed a near-term bullish breakthrough 50-day SMA barrier. A sharp US Dollar retracement from near 17-month tops was seen as one of the key factors behind the pair's impressive rally.
Adding to this, hopes over easing US-China trade tensions boosted investors' sentiment, which was evident from a fresh wave of risk-on trade and prompted some aggressive short-covering move around perceived riskier currencies - like the Kiwi.
The USD bulls held on the back-foot through the Asian session on Friday and the pair continued scaling higher for the second consecutive session as focus shifts to the upcoming key event risk - the keenly watched US monthly jobs report, popularly known as NFP.
Against the backdrop of diverging Fed- RBNZ monetary policies, a stronger than anticipated employment details, especially average hourly wage growth data, would be enough to attract some fresh selling around the major.
Momentum beyond the 0.6700 handle is likely to get extended towards late August swing high resistance near the 0.6725-30 region, above which the pair is likely to aim towards testing the 0.6765 supply zone.
On the flip side, the 0.6650-40 region now seems to act as an immediate support, which if broken is likely to accelerate the slide back towards the 0.6600 handle en-route 100-day SMA support near the 0.6575 zone.


Every now and then (all right, more now than then these days) the kids do something that makes me realize I do have a couple of geeklings in the making.
Today the boychild came with me and baby to her appointment at the local children's hospital. The place is amazing and has many specialty clinics including those for kids with orthopedic issues and burn victims. I prepped him a bit before we got there, telling him he might see kids that looked different than him, that had scars or were in wheelchairs and that he could say hi to them, but not stare, point and so on.
passes on a parent's fear of clowns?
I neglected to mention the clowns.
Boychild (after walking past the clown greeting patients) whispers: Is that a human?
Boychild: OK, not a robot then.
First, I get a cookie for not bursting out laughing. I also had to wipe away a tear of pride that he is totally on the lookout for robots disguised as humans. Preparing for the eventual war with Skynet and the robot hordes.
Me to girlchild: That's weird.
We have gotten to the point where we have different flavors of weird: weird cool, weird interesting, and weird gross-don't-do-that-again.
Finally, have you seen Star Wars Trouble? You play it just like regular Trouble except for a few things.
1) You get R2 sound effects (that you can turn off).
2) You get to start a new piece when you roll a 6 or if R2 is standing upright.
3) It came with stickers of various characters to put on the game pieces.
We played last night and had so much fun. I recommend adding it to your game collection. Whenever anyone rolled a 6 or an R2, the boychild would yell, "You can free another Rebel!"


text:
#region Copyright & License

// Copyright © 2012 - 2015 François Chabot, Yves Dierick
//
// Licensed under the Apache License, Version 2.0 (the "License");
// you may not use this file except in compliance with the License.
// You may obtain a copy of the License at
//
// http://www.apache.org/licenses/LICENSE-2.0
//
// Unless required by applicable law or agreed to in writing, software
// distributed under the License is distributed on an "AS IS" BASIS,
// WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
// See the License for the specific language governing permissions and
// limitations under the License.

#endregion

using Be.Stateless.BizTalk.ContextProperties;
using Be.Stateless.BizTalk.Dsl.RuleEngine;
using Be.Stateless.Extensions;

namespace Be.Stateless.BizTalk.Policies.Send.Batch
{
	public class AggregateProcessResolver : RuleSet
	{
		public AggregateProcessResolver()
		{
			Rules.Add(
				Rule("BatchAggregateProcessName")
					.If(() => Context.Read(TrackingProperties.ProcessName).IsNullOrEmpty())
					.Then(() => Context.Write(TrackingProperties.ProcessName, Factory.Areas.Batch.Processes.Aggregate))
				);
		}
	}
}


text:
Q: TMPro stopping rendering after sprite tag from dynamic SpriteAsset I am generating (or at least attempting to) a TMP_SpriteAsset at run time, and adding this to the list of fallbacks on the default SpriteAsset.
It is not possible to build the SpriteSheet at compile time, it has to be dynamic for this project.
To do this I am creating an empty TMP_SpriteAsset, along with empty texture and placing the sprites into the sheet as required.  I am creating a TMP_SpriteGlyph setting the properties, and then creating a TMP_SpriteCharacter with the unicode 0xFFFE and the glyph created previously.
Assigning a name to the character after it is created.
I then add the Character and then Glyph to spriteCharacterTable and spriteGlyphTable.
If at this point I attempt to use the sprites, they appear in the inspector and all values are correct as well as their bitmaps, co-ordinates and names, but TMPro cannot find them by name, and renders the unknown sprite question mark.
OK, so I call UpdateLookupTables() on my Sprite Asset after adding them, which is mentioned in the docs, however now, the text is only rendered up to the first sprite! at which point it stops, no text or sprites rendered after this point, nothing in the Log or Error log.  It just stops!
Inspecting the SpriteAsset and the glyphs and characters are all there as before!
I assume I am missing some key somewhere, anyone able to help?
Unity: 2019.4.26
TMPro: 2.1.4

A: In my case I had missed the metrics property of the Glyph!
I discovered this by reading through the private UpgradeSpriteAsset method of TMP_SpriteAsset.
I had created my glyph and only set the index, sprite, scale, and glyphRect properties, which will it seems allow it to appear in the inspector, but will cause it to not render, and even abort the rendering (I suspect no check the metrics property before trying to access somewhere in TMPro.


text:
Q: Querying entities throws "Invalid Operation Exception" on enum field I was just trying some features of entity framework 5 and kendo ui. I have a following ProductType enum
public enum ProductType {
    [Description("Hazardous")]
    Hazardous,
    [Description("Non Hazardous")]
    NonHazardous
}

This enum type is one of the field in the Product Entity.
[Table("Products")]
public class Product {
    [Key]
    [DatabaseGenerated(DatabaseGeneratedOption.Identity)]
    public int Id { get; set; }

    //Other Fields ...

    [Required(ErrorMessage="Product Type is Required")]
    public ProductType ProductType {get;set;}

}

The ProductType column in the underlying SQL Server Database is defined as (tinyint, not null).
I access list of Products in the following Controller Action of MVC
    public ActionResult _ProductList(int pageSize, int skip) {
        using (WorkUnit workUnit = new WorkUnit()) {
            IQueryable<Product> products = workUnit.ProductRepository.GetAllProducts()
                                                   .Include(p => p.Category);
            int total = products.Count();
            List<Product> productList = products.ToList<Product>(); //Throws InvalidOperationException
            return Json(new { total = total, data = productList }, JsonRequestBehavior.AllowGet);
        }
    }

Here is the description of the InvalidOperationException that is thrown on products.ToList() in the above controller action.
The 'ProductType' property on 'Product' could not be set to a 'Byte' value.
You must set this property to a non-null value of type 'ProductType'.

Any guesses why ToList() is throwing an InvalidOperationException.
Just for info, the Database existed previously, and the Entities were manually coded based on the Database as POCO's.
Edit
Here is the complete exception details
  System.InvalidOperationException was unhandled by user code
  HResult=-2146233079
  Message=The 'ProductType' property on 'Product' could not be set to a 'Byte' value. You must set this property to a non-null value of type 'ProductType'.
  Source=System.Data.Entity
  StackTrace:
       at System.Data.Common.Internal.Materialization.Shaper.ErrorHandlingValueReader`1.GetValue(DbDataReader reader, Int32 ordinal)
       at System.Data.Common.Internal.Materialization.Shaper.GetPropertyValueWithErrorHandling[TProperty](Int32 ordinal, String propertyName, String typeName)
       at lambda_method(Closure , Shaper )
       at System.Data.Common.Internal.Materialization.Shaper.HandleEntityAppendOnly[TEntity](Func`2 constructEntityDelegate, EntityKey entityKey, EntitySet entitySet)
       at lambda_method(Closure , Shaper )
       at System.Data.Common.Internal.Materialization.Coordinator`1.ReadNextElement(Shaper shaper)
       at System.Data.Common.Internal.Materialization.Shaper`1.SimpleEnumerator.MoveNext()
       at System.Collections.Generic.List`1..ctor(IEnumerable`1 collection)
       at System.Linq.Enumerable.ToList[TSource](IEnumerable`1 source)
       at KendoUI_Web_Demo.Controllers.HomeController._ProductList(Int32 pageSize, Int32 skip) in d:\Practice\ASP.NET_MVC\KendoUI_Web_Demo\KendoUI_Web_Demo\Controllers\HomeController.cs:line 52
       at lambda_method(Closure , ControllerBase , Object[] )
       at System.Web.Mvc.ActionMethodDispatcher.Execute(ControllerBase controller, Object[] parameters)
       at System.Web.Mvc.ReflectedActionDescriptor.Execute(ControllerContext controllerContext, IDictionary`2 parameters)
       at System.Web.Mvc.ControllerActionInvoker.InvokeActionMethod(ControllerContext controllerContext, ActionDescriptor actionDescriptor, IDictionary`2 parameters)
       at System.Web.Mvc.Async.AsyncControllerActionInvoker.<>c__DisplayClass42.<BeginInvokeSynchronousActionMethod>b__41()
       at System.Web.Mvc.Async.AsyncResultWrapper.<>c__DisplayClass8`1.<BeginSynchronous>b__7(IAsyncResult _)
       at System.Web.Mvc.Async.AsyncResultWrapper.WrappedAsyncResult`1.End()
       at System.Web.Mvc.Async.AsyncControllerActionInvoker.EndInvokeActionMethod(IAsyncResult asyncResult)
       at System.Web.Mvc.Async.AsyncControllerActionInvoker.<>c__DisplayClass37.<>c__DisplayClass39.<BeginInvokeActionMethodWithFilters>b__33()
       at System.Web.Mvc.Async.AsyncControllerActionInvoker.<>c__DisplayClass4f.<InvokeActionMethodFilterAsynchronously>b__49()
  InnerException:

A: There is a mismatch between the enum type which in your case is int based and your database where the column is byte (tinyint) based. You can fix this by setting the correct underlying type of your enum type:
public enum ProductType : byte
{
...
}