text:
Canadian scientists and Swiss surgeons discover cause of excess post-surgical scarring
The finding could improve recovery from abdominal and pelvic surgery
Kelly Johnston, Cumming School of Medicine
This is the view through a multi-photon microscope as macrophages (red) congregate at an injury site Kubes' Lab, Snyder Institute for Chronic Disease
The body is amazing at healing itself. However, sometimes it can overdo it. Excess scarring after abdominal and pelvic surgery within the peritoneal cavity can lead to serious complications and sometimes death. The peritoneal cavity has a protective lining containing organs within our abdomen. It also contains fluid to keep the organs lubricated. When the lining gets damaged, tissue and scarring can form, creating problems. Researchers at the University of Calgary and University of Bern, Switzerland, have discovered what's causing the excess scarring and options to try to prevent it.
"This is a worldwide concern. Complications from these peritoneal adhesions cause pain and can lead to life-threatening small bowel obstruction, and infertility in women," says Dr. Joel Zindel, MD, University of Bern and first author on the study who worked on this research as a Swiss National Science Foundation research fellow at the University of Calgary. "People sometimes require a second surgery."
The research published in Science, was conducted in mice and shows the excess scarring is caused by macrophages, a type of white blood cell that rushes to the surgical site to start to repair the injury.
"Joel developed a new method using the highly specialized imaging equipment in my lab that gave scientists the first look at what these macrophages are doing in real time," says Dr. Paul Kubes, PhD, principal investigator on the study and professor at the Cumming School of Medicine. "We are still working to understand why the macrophages take on this repair work as they are known for attacking pathogens. Whatever they are responding to, it's clear their involvement is causing the scarring problem."
UCalgary's Paul Kubes is principal investigator on the study.
Riley Brandt, University of Calgary
The researchers also discovered two ways to inhibit this natural response. They either removed the macrophages, or they introduced a drug to block the macrophage stickiness. Both processes were very effective in stopping the adhesions.
"We believe the macrophage response has not made the evolutionary leap to understand that surgery is beneficial and not a threat to survival," says Kubes. "It's possible, that the body is reacting to the surgery, that having the organs exposed to the environment is interpreted as a threat, like an attack from a predator. The body doesn't understand that the surgeon will do the critical repair work."
Macrophages are also present in humans, and the research team believes the response seen in mice is likely to translate to both adults and children. They hope to move to trials on human cells, soon, and eventually clinical trials.
When Zindel could leave the lab for a moment or two, he enjoyed hiking trails in Alberta.
supplied by Joel Zindel
"Every surgeon does operations for people who have these abdominal adhesions," says Zindel. "It would be amazing to be able to prevent this surgical complication. It would not only benefit individuals, it would create significant savings for the health-care system, by reducing hospital costs for readmission and surgery."
The basic research was funded by the Natural Sciences and Engineering Research Council while the clinical application was funded by the Canadian Institutes of Health Research (CIHR). Kubes is supported by Heart & Stroke and the CIHR Canada Research Chairs Program and Zindel is supported from a fellowship from the Swiss National Science Foundation.
This research was possible with support from the Nicole Perkins Microbial Communities Core Lab, the Live Cell Imaging Laboratory at the Cumming School of Medicine, and the Microscopy Imaging Center (MIC) of the University of Bern.
Infections, Inflammation and Chronic Diseases
The University of Calgary is uniquely positioned to find solutions to key global challenges. Through the research strategy for Infections, Inflammation, and Chronic Diseases in the Changing Environment (IICD), top scientists lead multidisciplinary teams to understand and prevent the complex factors that threaten our health and economies.
Paul Kubes is the lead of the Infections, Inflammation and Chronic Diseases strategy at the University of Calgary. He is a professor in Department of Physiology and Pharmacology at the Cumming School of Medicine (CSM) and a member of the Snyder Institute for Chronic Diseases at the CSM.
Joel Zindel is a clinician-scientist in training at the Department of Visceral Surgery and Medicine, Department for BioMedical Research University of Bern, Bern, Switzerland and at the Cumming School of Medicine, University of Calgary.
UCalgary researcher to lead global study to improve diagnosis and treatment for children infected by COVID-19
UCalgary research and diagnostics collaboration to benefit families throughout Alberta
Young mom welcomes UCalgary trial of simple new way to prevent blood clots
International research team solves 20-year mystery regarding fatal heart flaw
In the News: UToday
Research study leads to dramatic quality of life improvement for man with spinal cord injury
UCalgary researchers aim to revolutionize treatment for brain aneurysms
future of health care


Injuries have the potential to sideline people for weeks, months or permanently. Injury to the body can occur when participating in organized sports, fitness regimens or even after being in an accident.
Recovering from incidents that can impact mobility and range of motion takes time, but physical therapy can help the body acclimate to regular activity once more. Physical therapy also can help healthy people as well.
Those who have suffered a sprain or a broken bone or even spent a duration of time immobile in the hospital due to an illness are often prescribed physical therapy as part of their follow-up treatment. Physical therapy programs try to progressively increase strength, improve mobility and help the body return to a state where it can function as best as possible. In many cases, a person can regain his or her original capabilities.
According to the American Physical Therapy Association, a physical therapist is a trained and licensed medical professional who has the experience to diagnose physical abnormalities, restore physical function and mobility, maintain that function, and promote proper form for future activity. Physical therapy sessions can take place in hospitals, rehabilitation centers, fitness settings, private practices, and much more.
Not only can physical therapists react to and treat an injury, but they can also teach exercises, stretches and techniques to help prevent problems in the first place. Experts at Bay State Physical Therapy indicate that physical therapy extends beyond disabled or injured people. Physical therapists can educate a person on weaknesses in the body and can guide correction on poor body mechanics that cause pain. This way a person can make changes to prevent future pain and injury. Rather than being reactionary, healthy individuals can take a proactive approach to avoiding pain and injury.
• be given at-home work to further progress in between sessions.
While physical therapy can be used for recovery from strokes or paralysis, injuries, trauma, and musculoskeletal conditions, it also benefits healthy people. For example, women can use physical therapy to learn exercises that may prevent pelvic floor dysfunction. In addition, physical therapy can teach people how to improve their balance and prevent falls.
When people hear about physical therapy, they tend to think it is for people with injuries. While physical therapists can help heal injured parts of the body, physical therapy continues to evolve to assist with overall wellness.


Business writing ought to be both clear and concise. It is a type of professional Communicating. You will understand how to choose a fresh approach to business writing in the bottom up.
If you're among the many people in company for whom writing hasn't been a Big concern, you need to to know that a lack of composing skills is a higher and increased handicap with each passing year. Business Writing is a sort of communication that is written, usually with traditional structure and style. Knowing how to place your business it is an integral element in effective communication. Because of this, you need to talk a company writing handbook whenever you have any queries or doubt the truth of the Letter Wizard. Whether you run a small company or occupy a tiny corner of this org-chart for an enormous multinational corporation, it is possible that most your job is made up of communicating with others, most frequently in writing. What you write and how you write it are critically vital for your company success.
Several individuals may write letters to the exact same topic with the very Same or slightly different factors, and submit them a couple of days apart, so the problem stays on the Letters page to get a period of time. Recommendation letters are from time to time asked from former co-workers that are searching for a letter to see a brand new or new employer. You also don't have to be the just one to write a letter. When you compose a business letter, you must assume that your reader has enough time to examine it and is very likely to skim. Some varieties of company letter are somewhat more complex to write than others, but as you get experience in writing letters you will discover that understanding what things to say and the way to word it's largely a matter of common sense. In the majority of instances, the business letter is going to be the very first impression that you make on someone. Keep the following suggestions in mind as you compose and especially when you update your organization letters or memos.
Letters can be contingent on various content which can influence the Way of this letter. Whatever the tone you are using on your correspondence, your writing should remain concise, clear, and simple to read. Business letters should not go beyond one page unless absolutely necessary. They will need to follow a particular format, whichever kind they are. A business letter is an official record, using an established arrangement. Your very own small business letter should appear similar, but do not attempt to replicate the design.
Describe the kind of letter you are being requested to compose. Even if you're Shifting your letter to a person who is highly educated, you don't will need to use keywords and complicated paragraphs. If your letter is typed by another person, the typist's initials may be included two lines under the signature block. A covering letter will be the one which accompanies your CV when you are applying for employment. The next thing you ought to do when contemplating an official letter is to identify who you are writing it to. You should make an effort to deal with formal correspondence to a specific individual, but should you not know her or his name, at least try to include her or his name.
When you are finished writing, ask a Individual to read your letter and provide You with feedback, since they might spot errors you may have missed. Cover letters are an superb means to show that you understand the surroundings and culture of the organization and industry and show that you've got what they're trying to find. It is usually far better to personally sign the letter instead of employing an electronic replica of this signature. There's nobody approach to sign off casual letters. They are primarily used for individual communication. An informal letter can be written in nearly any way you decide on, but there are a number of organizational guidelines you will be able to follow in case you are unsure about what to write or the way to format your letter.
legitimacy. The company's letterhead is frequently an official solution to earn a wonderful first impression. If you make the decision to design a new business letterhead, you're likely to want to make certain that your other substances such as envelopes, business cards and also the website are consistent in the way they portray the brand.
Take under Consideration the kind and caliber of the paper which you use for Your own letterheads. It's essential that the look of your letterhead reflects the picture which you need to communicate. Try to remember that the letterhead will need to be printed. If you are likely to make a letterhead to your organization, you ought to know and understand the very important elements it should have. The official business letterhead, employed for correspondence at a choice of company, is unique for many facets.
Information regarding the sender. It is essential to make certain that your letterheads are top quality should you would like to achieve and maintain a professional image. A letterhead should have each of the simple contact information about you. A letterhead indicates your business is serious with your business enterprise and is more than prepared to assist. A specialist letterhead is a compulsory thing for virtually any business venture.
Your letterhead Isn't going to only provide the customer with your title and Address, it is also likely to make a feeling regarding the grade of your product or solutions. A letterhead does not just represent an organization but reveals professionalism on correspondents created in the name of a business. Your organization letterhead is frequently the very first potential for your audience to hold your business identity in their hands. After reading the aforementioned information you may now understand how to create the ideal letterhead to your company.
Not many companies, however, can be readily associated with any specific image. A business thank you letter format is comparable to other small company writing. When choosing your colour scheme, remember the character you would like to express to your business. When you analyze your organization, you might initially feel that everybody in your industry is essentially the specific same. A strictly money based firm might get by without the use of a computer in case the transactions are restricted in volume and are not complicated transactions. Many companies utilize other pale colors like cream or pale yellow. There are a whole lot of different medical-related companies!
Reflecting the organization's branding, such as and logos or special images. Consistently write a line saying that it needs to be ignored if the necessary action is taken at the close of the letter. An experience letter follows precisely the same format for a certificate and serves the very same purpose. In some instances, what's discussed in 1 letter cannot be shared with a different department. The very first factor to emphasize when composing a very good exercise sales letter would be to concentrate on the potential customer. Writing a great physical fitness sales letter is going to be a requirement sooner or later in your private training livelihood.
Thank you letters are the perfect way to convey your admiration to an individual. It's crucial when writing a business letter to not forget that conciseness is important. A company introduction letter must come with a business booklet.
The letter should include what in detail, in order to avoid Ambiguity, in the event of a dispute. Letter writing will always help you stay in the heads of your clientele and customers. Formal letters still maintain an extremely important area in the industry world. Usually, an official letter is brief and has just a couple of major body paragraphs, however in case that you need to ask about a string information it's possible to incorporate it all in the principal body, spread over a few paragraphs. Composing an official invitation letter is actually simpler compared to informal ones.
Letter needs to be published on the business letterhead. A nicely crafted letter Printed on the corporation's letterhead proves to be an effective communication technique. Your letter should reflect that you are serious and ready to cover all of the dues once potential. Ensure you compose the letter as professionally as you have the ability to. If you're sending out a cover letter or a job schedule, then it is a good idea to tackle the individual concerned with a salutation.
A general principle, for all types of business letter is to utilize exceptional Fantastic stationery. You're ready to elaborate with illustrations, to place your point forward. You might also undergo a few expert letter format examples for help. You may find a lot of regular business letter examples on many different websites online.
Use bullet points or brief headings to make the Letter simpler to read. Your cover letter shouldn't be overly long. Drafting a cover letter could be among the most stress inducing facets of the search. The cover letter is a valuable supplement that can help to make your abilities and expertise stick out. Along with that, your cover letter may even make it in the hands of the person you dealt with it ! You CANNOT use the particular exact same cover letter to use for every job.
Communication, is you've got some opportunity to pause and think about what you want to convey, the order of these situations you need to say, and at the specific same time be in a position to choose the right words to provide a crystal clear message. If you are able to form the letter. The majority of the second, writing that letter incorporates minimal danger. The letter will be filed in your personnel file, to which you won't have access, Hurwitz explained. The introductory sales letter needs to be limited to one page. The missing customer sales letter is meant for clients not having purchased products or have canceled their solutions.
It is you are selling, " she clarified. It's imperative to learn to write letters clearly and effectively. Apology letters need to prevent referring to sensitive personal matters, since they could be read by other people. The best means of locating this type of expert letter is net or inside a publication.
If You'd like the letter to arrive sooner, you can use a courier for same-day shipping. On the reverse side, if you refuse to compose a letter which may be a problem also. A letter of inquiry is a type of interest letter in which the writer asks about the opportunity of a job opening in the future. A good informative letter follows a couple of essential guidelines.
Give a summary of the points you're going to be making in the letter. Write a letter To someone else within an equally enticing positionyou know they are out there, which there are a lot of people who are ready to speak to you! Composing a very impressive and attractive letter is one of the most daunting tasks. Writing English small business letters isn't the simplest task.
In the very first paragraph, describe why it is that you're writing the letter. Sales letters can be very beneficial in attaining a provider's objective. The holiday party sales letter offers you an opportunity to offer your product because a potential gift for your clients' family, friends or work associates.
You just have to figure out what kind of resume or covering letter is going to be Most suitable for you. An informal letter could be written in any way you select, however you will find a couple of organizational guidelines that you may follow if you are unsure about what to write or the way to format your correspondence. Personal letters to friends are somewhat more casual.
An email is an example of an interactive writing, meaning that we are Writing to someone instead of just for somebody to read. In the event of paperless offices, a business email is the vital type of communication, no matter the topic matter. A company email, on the flip side, also is composed usually utilizing a computer or digital means, but it's electronically discharged to the receiver in a matter of merely a couple of seconds.
Describe how you're likely to result in the company from Day One. Firms Like to understand that you're eager to learn. If they see the same generic letter all the time, they may get annoyed! Most companies (especially big ones) might not have the time to read everyone's cover letters, but if they do, it's your chance to convey your interest along with how and why you would be an ideal fit in their view. Before you can even begin to expect to earn their business, you should demonstrate your capability to deliver on what your service or product promises. Today you must write about the business enterprise. For those who possess a small company or wish to create a welcoming, friendly feel, then a hand-drawn logo may be the perfect thing to do.
Thirdly, cover letter examples provide the position-seeker the chance to Know what format to compose their correspondence in. Finally, they offer the Position-seeker the opportunity to know what tone to use in composing their Application letters. Second, the cover letter examples provide the Position-seeker the opportunity to comprehend what things to add and what not to Incorporate within their application.


Mr. Muffler in Howell offers the best deals.
One visit to Williamston, and you'll probably want to move there! The City's website will have all the details about life in Williamston.
If you're the entrepreneurial type, the Williamston Chamber of Commerce website can help you open a business there!
3160 E. Grand River Ave.
Explore our unique shops, art galleries, historical museum, and antique stores. Enjoy one of our many fun community events. All within walking distance of each other - Williamston is a beautiful walking community.


text:
PlayStation Store Update for Jan 14th 2010
January 15th, 2010 / XTREME PSP / PlayStation Store
This week on the PSP Store, you will find a two new downloadable games in Europe, including Army of Two: The 40th Day as well as a new Minis title. The US on the other hand also has a new downloadable game and new minis title available for purchase too. Two new playable demos are available from the European Store, including Football Manager Handheld 2010 and the US has a few new XMB themes and a Gran Turismo Add-on pack, all available for free.
European Additions:
Special Offers (From the 7th Jan until the 21st of January)
Patapon 2 (PSP) (was – £19.99/€29.99 now – £14.99/€19.99)
Daxter (PSP) (was – £14.99/€19.99 now – £7.99/€9.99)
Pirates of the Caribbean: Dead Man's Chest (PSP) (was – £15.99/€19.99 now – £7.99/€9.99)
Pirates of the Caribbean: At World's End (PSP) (was – £23.99/€29.99 now – £11.99/€14.99)
Monster Hunter Freedom Unite (PSP) (was – £23.99/€29.99 now – £16.99/€20.99)
Downloadable Games
Army of Two: The 40th Day (released on Friday the 15th of January) (£31.99/€39.99)
Star Wars: Battlefront II (£15.99/€19.99)
PSone Games (emulated for PS3/PSP)
Constructor (£3.99/€4.99)
Deflector (£3.49/€3.99)
Army of Two: The 40th Day
Football Manager Handheld 2010
US Additions:
Downloadable Games (also available from PS3 storefront)
Luxor: The Wrath of Set ($9.99)
PSP minis
Dynogems ($2.99)
PSP Demos (free)
Lunar: Silver Star Harmony Demo
Add-on Game Content (also available from PS3 Storefront)
Gran Turismo PSP Car Pack
PSP Themes (also available from PS3 Storefront)
Savage Moon: The Hera Campaign Big Guns PSP Theme
Savage Moon: The Hera Campaign Red Planet PSP Theme
Savage Moon: The Hera Campaign Tower PSP Theme

redpajama_set_name: RedPajamaCommonCrawl


text:
<?php

namespace Proxies\__CG__\CR\GSBRBundle\Entity;

/**
 * DO NOT EDIT THIS FILE - IT WAS CREATED BY DOCTRINE'S PROXY GENERATOR
 */
class rapportVisite extends \CR\GSBRBundle\Entity\rapportVisite implements \Doctrine\ORM\Proxy\Proxy
{
    /**
     * @var \Closure the callback responsible for loading properties in the proxy object. This callback is called with
     *      three parameters, being respectively the proxy object to be initialized, the method that triggered the
     *      initialization process and an array of ordered parameters that were passed to that method.
     *
     * @see \Doctrine\Common\Persistence\Proxy::__setInitializer
     */
    public $__initializer__;

    /**
     * @var \Closure the callback responsible of loading properties that need to be copied in the cloned object
     *
     * @see \Doctrine\Common\Persistence\Proxy::__setCloner
     */
    public $__cloner__;

    /**
     * @var boolean flag indicating if this object was already initialized
     *
     * @see \Doctrine\Common\Persistence\Proxy::__isInitialized
     */
    public $__isInitialized__ = false;

    /**
     * @var array properties to be lazy loaded, with keys being the property
     *            names and values being their default values
     *
     * @see \Doctrine\Common\Persistence\Proxy::__getLazyProperties
     */
    public static $lazyPropertiesDefaults = array();

    /**
     * @param \Closure $initializer
     * @param \Closure $cloner
     */
    public function __construct($initializer = null, $cloner = null)
    {

        $this->__initializer__ = $initializer;
        $this->__cloner__      = $cloner;
    }

    /**
     *
     * @return array
     */
    public function __sleep()
    {
        if ($this->__isInitialized__) {
            return array('__isInitialized__', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'id', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'dateRapport', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'bilan', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'motif', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'visiteur', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'medecin');
        }

        return array('__isInitialized__', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'id', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'dateRapport', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'bilan', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'motif', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'visiteur', '' . "\0" . 'CR\\GSBRBundle\\Entity\\rapportVisite' . "\0" . 'medecin');
    }

    /**
     *
     */
    public function __wakeup()
    {
        if ( ! $this->__isInitialized__) {
            $this->__initializer__ = function (rapportVisite $proxy) {
                $proxy->__setInitializer(null);
                $proxy->__setCloner(null);

                $existingProperties = get_object_vars($proxy);

                foreach ($proxy->__getLazyProperties() as $property => $defaultValue) {
                    if ( ! array_key_exists($property, $existingProperties)) {
                        $proxy->$property = $defaultValue;
                    }
                }
            };

        }
    }

    /**
     *
     */
    public function __clone()
    {
        $this->__cloner__ && $this->__cloner__->__invoke($this, '__clone', array());
    }

    /**
     * Forces initialization of the proxy
     */
    public function __load()
    {
        $this->__initializer__ && $this->__initializer__->__invoke($this, '__load', array());
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific loading logic
     */
    public function __isInitialized()
    {
        return $this->__isInitialized__;
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific loading logic
     */
    public function __setInitialized($initialized)
    {
        $this->__isInitialized__ = $initialized;
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific loading logic
     */
    public function __setInitializer(\Closure $initializer = null)
    {
        $this->__initializer__ = $initializer;
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific loading logic
     */
    public function __getInitializer()
    {
        return $this->__initializer__;
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific loading logic
     */
    public function __setCloner(\Closure $cloner = null)
    {
        $this->__cloner__ = $cloner;
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific cloning logic
     */
    public function __getCloner()
    {
        return $this->__cloner__;
    }

    /**
     * {@inheritDoc}
     * @internal generated method: use only when explicitly handling proxy specific loading logic
     * @static
     */
    public function __getLazyProperties()
    {
        return self::$lazyPropertiesDefaults;
    }

    /**
     * {@inheritDoc}
     */
    public function getId()
    {
        if ($this->__isInitialized__ === false) {
            return (int)  parent::getId();
        }

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'getId', array());

        return parent::getId();
    }

    /**
     * {@inheritDoc}
     */
    public function setDateRapport($dateRapport)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'setDateRapport', array($dateRapport));

        return parent::setDateRapport($dateRapport);
    }

    /**
     * {@inheritDoc}
     */
    public function getDateRapport()
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'getDateRapport', array());

        return parent::getDateRapport();
    }

    /**
     * {@inheritDoc}
     */
    public function setBilan($bilan)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'setBilan', array($bilan));

        return parent::setBilan($bilan);
    }

    /**
     * {@inheritDoc}
     */
    public function getBilan()
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'getBilan', array());

        return parent::getBilan();
    }

    /**
     * {@inheritDoc}
     */
    public function setMotif($motif)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'setMotif', array($motif));

        return parent::setMotif($motif);
    }

    /**
     * {@inheritDoc}
     */
    public function getMotif()
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'getMotif', array());

        return parent::getMotif();
    }

    /**
     * {@inheritDoc}
     */
    public function setVisiteur(\CR\GSBRBundle\Entity\visiteur $visiteur = NULL)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'setVisiteur', array($visiteur));

        return parent::setVisiteur($visiteur);
    }

    /**
     * {@inheritDoc}
     */
    public function getVisiteur()
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'getVisiteur', array());

        return parent::getVisiteur();
    }

    /**
     * {@inheritDoc}
     */
    public function setMedecin(\CR\GSBRBundle\Entity\praticien $medecin = NULL)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'setMedecin', array($medecin));

        return parent::setMedecin($medecin);
    }

    /**
     * {@inheritDoc}
     */
    public function getMedecin()
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'getMedecin', array());

        return parent::getMedecin();
    }

    /**
     * {@inheritDoc}
     */
    public function isMotifValid(\Symfony\Component\Validator\Context\ExecutionContextInterface $context)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'isMotifValid', array($context));

        return parent::isMotifValid($context);
    }

    /**
     * {@inheritDoc}
     */
    public function isBilanValid(\Symfony\Component\Validator\Context\ExecutionContextInterface $context)
    {

        $this->__initializer__ && $this->__initializer__->__invoke($this, 'isBilanValid', array($context));

        return parent::isBilanValid($context);
    }

}

redpajama_set_name: RedPajamaGithub


text:
package com.streamsets.datacollector.creation;

import com.streamsets.pipeline.api.ErrorCode;
import com.streamsets.pipeline.api.GenerateResourceBundle;

@GenerateResourceBundle
public enum CreationError implements ErrorCode {

  CREATION_000("Failed to instantiate stage '{}' [ERROR]: {}"),
  CREATION_001("Failed to instantiate config bean '{}' [ERROR]: {}"),
  CREATION_002("Configuration definition missing '{}', there is a library/stage mismatch [ERROR]"),
  CREATION_003("Failed to access config bean [ERROR]: {}"),

  CREATION_004("Could not set default value to configuration [ERROR]: {}"),

  CREATION_005("Could not resolve implicit EL expression '{}': {}"),

  CREATION_006("Stage definition not found Library '{}' Stage '{}' Version '{}'"),

  CREATION_007("Stage definition Library '{}' Stage '{}' Version '{}' is for error stages only"),
  CREATION_008("Stage definition Library '{}' Stage '{}' Version '{}' is not for error stages"),

  CREATION_009("Pipeline error handling is not configured"),

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Nephrotic Syndrome (NS) refers to the kidney disorder with a series of symptoms, such as large proteinuria, severe edema, hypoalbuminemia, hyperlipidaemia. With the development of nephrotic syndrome, you may get gradually reduced kidney function, and some other severe symptoms can occur. Then why do you see anorexia with nephrotic syndrome? Read on, you can get answer.
Here are some of the common causes of anorexia in nephrotic syndrome.
1. With a low kidney function in nephrotic syndrome, there will be too much toxins and wastes building up in blood, which can stimulate the gastrointestinal system, and it can cause the symptoms such as diarrhea, chronic constipation, peptic ulcer, etc, all these symptoms can induce anorexia.
2. Kidneys also have function of regulating acid-base balance. When kidneys cant work well in NS, it can lead to the acidosis, which can also lead to the anorexia in nephrotic syndrome.
3. When your body cant absorb enough zinc or iron due to the limited diet in daily life for NS, it will cause thyroid hypofunction, this is another reason of anorexia.
Above are some of the main causes of anorexia in nephrotic syndrome, and most of the causes are related with low kidney function in patients. In this condition, you need to take medical treatment to improve kidney function, then the symptoms can be controlled from root.
Here we suggest the Immunotherapy and Micro-Chinese Medicine Osmotherapy to NS patients, both are the featured treatment in Shijiazhuang Kidney Disease Hospital.
The Immunotherapy is used to regulate your immune system and improve the immunity, then it can prevent further inflammations in kidneys and protect your kidney function, and it can also remove the immune complexes out into urine, which can make a good blood environment for further treatment.
Micro-Chinese Medicine Osmotherapy is an external and herbal based treatment, and it has the function of repairing damaged kidney tissues and improving kidney function. Then it can stop your progression with nephrotic syndrome, and control your severe symptoms from root.
If you want to learn more about the symptoms and treatment for nephrotic syndrome, you can leave a message below, or you can also send e-mail to chinakidneyhospital@gmail.com, we can give more help.


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Ex-HealthSouth CFO Speaks in Fraud Case
JAY REEVES
A former top aide to HealthSouth founder Richard Scrushy testified in federal court Friday about a tape recording he made of a conversation they had a day before the government accused Scrushy and the company of massive accounting fraud.
While questioning former chief financial officer William T. Owens, defense attorney Tom Sjoblom suggested that Owens was behind the scandal that has shaken the rehabilitation giant.
Owens testified that his wife was worried about him going to prison for signing "phony financial statements," confirming what he said on the tape recording made last month.
Asked whether Scrushy told him to "do the right thing," Owens wasn't allowed to answer because of an objection by government attorneys.
Sjoblom honed in on the company's finances and structure in dozens of subsequent questions to Owens, who repeatedly invoked his constitutional right against self-incrimination.
"Mr. Owens, Mr. Scrushy built this company with his sweat and blood before he knew you, didn't he?" Sjoblom asked. The judge didn't let Owens answer.
"The reason we're all here, Mr. Owens, is because of you, isn't it?" Sjoblom asked later. Owens wasn't allowed to answer.
Sjoblom suggested that Owens _ who became CEO last August after Scrushy temporarily stepped aside _ was mad about taking a pay cut when Scrushy returned and Owens resumed his job as CFO. Sjoblom said the cut was from $1.8 million to $1 million.
The defense attorney asked Owens if he was demoted to CFO because he was part of a "coup" to remove Scrushy as chairman while Owens was CEO. Owens took the Fifth.
Attorneys seeking to lift a freeze on Scrushy's assets subpoenaed Owens to testify about the tape recording. U.S. District Judge Inge Johnson allowed the testimony over the government's objections and granted a partial unfreezing of assets so Scrushy can pay income taxes. Johnson did not disclose the amount of money he released, but Scrushy's unpaid tax liability for this year previously was estimated in court to be as much as $17 million.
Court adjourned for the weekend after four hours of testimony Friday and was scheduled to resume Monday morning.
In the recording, played in court Thursday, Scrushy and Owens were heard discussing fears of going to jail and how to clean up the company's finances.
"I think we ought to go down fighting," Scrushy was heard to say. Scrushy, fired last week as chief executive and chairman, also made a reference that implied Owens "engineered" false numbers.
Owens is among nine former HealthSouth executives who have reached plea deals on federal fraud charges arising from an accounting scam the government contends was orchestrated by Scrushy.
Neither Scrushy nor HealthSouth has been charged with a crime, but Sjoblom said in court he expects Scrushy to be indicted soon.
Sjoblom formerly was an attorney for the Securities and Exchange Commission, which sued Scrushy and the company on March 19. The government accuses them of overstating HealthSouth earnings by more than $2.5 billion since 1997 to meet Wall Street expectations and keep stock prices high.
Scrushy has denied any wrongdoing through his attorneys. He repeatedly cited his right to avoid self-incrimination in refusing to answer questions earlier in the hearing.
The judge previously froze Scrushy's assets temporarily, but government lawyers said he was seeking access to $70 million _ $10 million to finance a lifestyle that includes four massive homes, a yacht and airplanes, and $60 million to pay taxes and his lawyers.
The hearing included testimony about evidence because government lawyers said they had to show they could win the lawsuit to convince the judge to maintain the freeze on Scrushy's assets.
Reeling financially from the scandal, HealthSouth was unable to make a $367 million payment on bonds and interest earlier this month. While lenders could force bankruptcy, HealthSouth said Thursday banks had agreed to delay any action until May 1 as it tries to come up with the money.
Birmingham-based HealthSouth calls itself the largest U.S. provider of outpatient surgery, and diagnostic, imaging and rehabilitative services. It has more than 51,000 employees at almost 1,700 facilities in every state and abroad.


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Home » Press » Ohio union members stand together, strong
Ohio union members stand together, strong
Decision won't stop union growth as workers organize to give voice to shared values
(June 27, 2018) Today's U.S. Supreme Court ruling in favor of wealthy and corporate interests' attempt to silence workers and their unions won't stop our members from working to build a better life for themselves, those they serve and their communities.
Union members and supporters of workers' rights across the nation are standing together in solidarity, committed to their unions despite today's ruling against unions by the U.S. Supreme Court.
"We're sticking with our union," said OFT President Melissa Cropper. "Working people know that the things they want - decent pay, quality healthcare, safe workplaces and fair treatment - are what our union fights for."
Cropper said the case itself while before the Court already has led to greater member activism and a stronger voice for workers.
"This decision today is a momentary triumph for the wealthy special interests who backed this lawsuit," she said. "But the voices of working people will not go unheard. And unions, such as ours, remain the best way to make sure decision-makers - at work or in the halls of government - are listening."
The Supreme Court's decision, in a case called Janus v. AFSCME, invalidates state laws allowing labor unions to collect fees from everyone in a bargaining unit, including nonmembers, to pay the costs of bargaining and other representation the union is required to provide to everyone, including nonmembers.
Even though the decision overruled a precedent that had stood for more than 40 years, this outcome had been largely anticipated by labor leaders.
Acknowledging the short-term challenges presented by the decision, Cropper said the union already has taken steps to comply with the ruling.
"We have the commitment of our members to meet these challenges," she said. "Our fight for our shared interests and values continues. We're not going anywhere. This is just a new chapter in our fight against union busters who viciously attack the rights of working people like they tried to do with Senate Bill 5.
"Strong unions make strong communities," she added. "Our members and the people they serve understand that, they lived it during our fight to beat back SB 5 and preserve workers' rights in Ohio."
"This court got it wrong today," she said. "But as we carry this fight forward - where our members work, in the communities they serve, and at the ballot box in November - we believe the court of public opinion will get this right."


The draw for the first round of the Carabao Cup has taken place and Town have been drawn at home to Burton Albion.
We were in the north section of the competition with our ball number 32 drawn out before Burton's 7.
The competition has seen Town do well in recent years with memorable games with the likes of Derby, Swansea, Arsenal, Crystal Palace and Chelsea. Last season we went out in a close fought game away to Nottingham Forest.
The game will be played the week commencing the 13th August and we will bring you full details as soon as they are confirmed.


I was searching for a Property and found this listing (MLS® #4848502). Please send me more information regarding 1 Route 22, Amenia, NY, 12501. Thank you!
I'd like to request a showing of 1 Route 22, Amenia, NY, 12501 (MLS® #4848502). Thank you!


Before you start, talk with your doctor to be sure it won't have side effects for you.
Don't use your phone, laptop, or tablet at bedtime.
If you'd like to try a new way to treat your migraines, your doctor can tell you how well it works and if there are any risks. She may know of an expert who specializes in these treatments. And she can check to make sure they won't have bad side effects.


How to Stay Motivated If you re like me, it s not always easy to stay motivated to build your MLM. How to stay motivated when you are constantly being told by others that you got scammed and you will loose all your money? They tell you that they thought you were smarter than that and they [ ] The post 3 Best Tips on How to Stay Motivated MLM Success Tips #105 appeared first on Success With JS.
Why Snapchat? You must have seen this yellow symbol all over the place in social media and you are probably thinking why Snapchat is all over the place? The main reason is that Snapchat has added some pretty interesting features that make it especially important for the social media landscape. These changes result in the [ ] The post Why Snapchat Blogging Success Tips #104 appeared first on Success With JS.
Being Determined Are you being determined? What does it mean to be determined? I think it means that when you have something you want done, you don t give up until you get it done. My Wife is Super Determined When she puts her mind to it, nothing stops her. Not even having two babies that [ ] The post Being Determined Health Success Tips #103 appeared first on Success With JS.
[Success Story Saturday] What Happened Just 48 Hours After Attending the MLSP Retreat for One Member?
Snapchat 2.0 is a Game Changer!!
Record Your Desktop Are you looking to record your desktop? Have you been looking for a tutorial on how to use OBS? A tutorial on using Open Broadcaster Studio? I put together this short tutorial, nothing perfect or fancy, just showing you how to do the basics. Enjoy. As always, please share if you got [ ] The post How to record your desktop using OBS Tutorial #1 appeared first on Success With JS.
Effectively Schedule Social Media Automation Do you use Social Media to promote your business? Are you doing Attraction Marketing? Are you Doing online Branding? If you spend any amount of time on Social Media trying to promote your business or your brand then you know how time consuming it can be, especially if you are [ ] The post Effectively Schedule Social Media Automation With Buffer Tutorial #2 appeared first on Success With JS.


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Glossary: Important Terms at Our Fertility Clinic
Adhesion: Scar composed of band-like tissue, attached to organ surfaces, capable of connecting, covering or distorting organs, such as tubes, ovaries, uterus, and bowel.
Anti-sperm antibody test: A test in which the blood of the female partner and her partner's semen are examined to detect antibodies to sperm. Antibodies can contribute to infertility.
Assisted reproductive technologies (ART): A collective name for advanced infertility treatments utilizing invitro (laboratory) techniques to assist with gamete handling and fertilization. Includes in-vitro fertilization embryo transfer (IVF-ET) gamete intrafallopian transfer (GIFT), zygote intrafallopian transfer (ZIFT) and tubal embryo transfer (TET), intra-cytoplasmic sperm injection (ICSI) and assisted hatching.
Biochemical pregnancy: A pregnancy diagnosed by the presence of the pregnancy hormone HCG, in the blood, but no fetus develops by ultrasound, and the pregnancy stops developing very early.
Blastocyst: Multicellular embryo that is seen five to six days after fertilization.
Cervix: The lower section of the uterus that protrudes into the vagina and dilates during labor to allow the passage of the infant.
Clinical pregnancy: A pregnancy confirmed by an increasing level of the pregnancy hormone hCG and the presence of a gestational sac detected by ultrasound.
Conceptus: A general term referring to the product of the union of the oocyte and the sperm cell.
Conscious sedation (twilight sleep): A non-invasive way for administrating medications to render a procedure very comfortable. Does not involve general anesthesia.
Controlled Ovarian Hyperstimulation: The administration of hormone medications to stimulate the ovaries to produce multiple eggs.
Corpus luteum: A special gland that forms on the surface of the ovary at the site of ovulation. It produces progesterone during the second half of the menstrual cycle and in early pregnancy. Its function is also to prepare the uterine lining for implantation by the fertilized egg.
Cryopreservation (embryo, oocyte and sperm freezing): A procedure used to preserve (by freezing) and store embryos or gametes (sperm or eggs).
Diminished Ovarian Reserve: A large reduction in the ability of the ovary to produce good quality eggs. Reasons include advanced maternal age (older than 40), congenital, medical, or surgical causes.
Donor insemination: The introduction of sperm from a donor into a woman's vagina or cervix using instruments, in order to achieve a pregnancy.
Ectopic Pregnancy: A pregnancy in the fallopian tube, or elsewhere outside the lining of the uterus. Unfortunately, it cannot develop into a healthy baby.
Egg Retrieval: The procedure in which eggs are obtained by a needle, from ovarian follicles, removing the fluid and the egg by suction. Also called oocyte aspiration.
Embryo: The developing conceptus from approximately the second week until approximately the end of the second month.
Embryo Transfer: Placement of embryos into a woman's uterus after in vitro fertilization.
Endometriosis: The presence of endometrial tissue (the normal uterine lining) in abnormal locations such as the ovaries or peritoneal (pelvic) cavity.
Endometrium: The lining of the uterine cavity. This is where the embryo implants.
Estrogen: The primary female hormone; produced mainly by the ovary from puberty to menopause.
Fallopian tubes: A pair of tubes that conduct the egg from the ovary to the uterus. Normal fertilization takes place within this structure.
Fertilization: The fusion of sperm and egg.
Fetus: The unborn offspring from the eighth week after conception to the moment of birth.
Fimbria: Finger-like outer ends of the Fallopian tubes.
Follicle: The fluid-filled sac in the ovary, in which the egg develops and from which the egg is released during ovulation, or aspiration.
Follicular Phase: The first half of the menstrual cycle when ovarian follicle development takes place, also called the pre-ovulatory stage.
Follicle Stimulating Hormone (FSH): A hormone produced and released from the pituitary that stimulates the ovary to ripen a follicle for ovulation.
Frozen embryo transfer: The placement of thawed embryos into the uterus.
Gamete: A generic term referring to either sperm or the oocyte (egg).
Gamete intrafallopian transfer (GIFT): The direct transfer of a mixture of sperm and eggs into the fallopian tube immediately following egg retrieval. Fertilization takes place inside the tube.
Gestation: The period of time from conception to birth.
Gestational carrier (Surrogate): A woman who carries a pregnancy for another couple. The pregnancy is derived from the egg and sperm of the couple. The gestational carrier has no genetic relationship to the resulting child.
Human chorionic gonadotropin (hCG): A hormone produced by the placenta: It is the hormone of pregnancy and its detection is used in pregnancy tests. It is also the contents of the "trigger shot" given to induce ovulation.
Hyperstimulation syndrome: A possible side effect of medically induced ovulation, characterized by swollen, painful ovaries and, in some cases, the accumulation of fluid in the abdomen and chest.
ICSI (intracytoplasmic sperm injection): A procedure in which a single sperm is injected directly into an egg; this procedure is most commonly used to overcome male infertility problems.
Implantation: The embedding of the fertilized egg in the lining of the uterus.
Insemination: Injection of sperm into the uterus (intrauterine) or cervix (intracervical) for the purpose of producing a pregnancy.
IUI (intrauterine insemination): Placement of sperm into the uterus to facilitate fertilization.
In vitro fertilization (IVF): A process in which an egg and sperm are combined in a laboratory dish to facilitate fertilization. If fertilized, the resulting embryo is transferred to the woman's uterus.
Intramuscular Injection: Injection administered into the muscular tissue (buttocks, thigh).
In Vitro Fertilization/Embryo transfer (IVF-ET): A procedure in which oocytes are removed transvaginally from ovarian follicles, fertilized artificially, and placed intrauterine through a specialized catheter for embryo transfer.
Laparoscopy: A surgical procedure to view and evaluate the pelvic organs. During the procedure a long, narrow telescope-like instrument, called a laparoscope, is inserted through an incision in or below the woman's navel. One or two other incisions may be made for inserting additional instruments. Can be diagnostic or therapeutic (used to treat any abnormalities found during the procedure).
Luteal Phase: The last fourteen days of the menstrual cycle after ovulation has occurred. It is associated with progesterone production. Also called the post ovulatory stage.
Lutenizing hormone (LH): A hormone produced and released by the pituitary; helps in egg development, hormone production and ovulation.
Male Factor: Any cause of infertility due to low sperm count or problems with sperm function that make it difficult for a sperm to fertilize an egg under normal conditions.
Micromanipulation: The IVF laboratory process whereby a single sperm is injected directly into the egg to facilitate fertilization, (ICSI) or the shell around the embryo is thinned to facilitate hatching (Assisted Hatching).
Miscarriage (also called spontaneous abortion): A pregnancy ending in the spontaneous loss of the embryo or fetus before 20 weeks of gestation.
Multifetal pregnancy reduction: A procedure used to decrease the number of fetuses a woman carries and improve the chances that the remaining fetuses will develop into healthy infants.
Oocyte: The egg produced by the ovaries each month. Also called the ovum (gamete).
Ovarian stimulation: The use of drugs (oral or injected) to stimulate the ovaries to develop follicles and eggs.
Ovaries: The female sex glands with both a reproductive function (releasing eggs) and an endocrine function (producing the hormones estrogen and progesterone).
Ovulation: The release of a mature egg from the follicle at the surface of the ovary.
Ovulation Induction: The administration of hormone medications to stimulate the ovaries to produce multiple eggs. Sometimes called controlled ovarian hyperstimulation.
Ovulatory dysfunction: A diagnostic category used when a woman's ovaries are not producing eggs normally. It includes polycystic ovary syndrome.
Pituitary Gland: A gland located at the base of the brain, below the hypothalamus, which controls almost every endocrine gland in the body. Therefore it controls human growth, development and reproduction.
Progesterone: A hormone produced and released by the corpus luteum of the ovary during the second half of an ovulatory cycle. It is necessary for the preparation of the lining of the uterus for the implantation of the fertilized egg and maintenance of the early pregnancy.
SART registry: An ongoing collection of IVF results from participating clinics developed and maintained by SART, a society affiliated with the American Society of Reproductive Medicine.
SCSA (Sperm Chromatin Structure Analysis): A test to evaluate the structure of genetic contents of sperm. This test may be used in some specific cases of infertility and recurrent pregnancy loss.
Semen: The sperm and seminal secretions ejaculated during orgasm by the male.
Semen Analysis: The examination of a semen sample for sperm volume, count, motility, morphology and presence of white blood cells.
Sex selection: A method by which intended parents can pre-select the sex of their child.
Sperm: Male reproductive cells
Spermatoza: Sperm.
Sperm washing: The separation of sperm from seminal fluid to prepare the sperm for intrauterine insemination.
Subcutaneous injection: Injection administered into the soft tissue beneath the skin (superficial)
Surrogate (Gestational carrier): A woman who is inseminated either directly or through IVF with the sperm of a man who is not her partner for purposes of conceiving and carrying a child to be reared by the biological father and his wife.
Transvaginal Aspiration: A method of retrieving eggs out of ovarian follicles by needle aspiration through the vagina.
Tubal embryo transfer (TET): A process where an early stage embryo is transferred to the fallopian tube via laparoscopy.
Tubal factor: A diagnostic category used when the woman's fallopian tubes are blocked or damaged, making it difficult for the egg to be fertilized or for an embryo to travel to the uterus.
Tubal patency: Unobstructed fallopian tubes.
Unexplained cause of infertility: A diagnostic category used when no cause of infertility is found in either the woman or the man.
Uterine factor: A structural or functional disorder of the uterus that results in reduced fertility.
Uterus: The reproductive organ that houses, protects and nourishes the developing embryo, fetus and baby.
Ultrasound: A technique for visualizing the follicles in the ovaries and fetus in the uterus. It is useful for evaluation of the follicles, endometrium, uterus, and for evaluation of fetal growth and viability (heart motion).
Vagina: A tubular passageway in the female connecting the external sex organs, labia with the cervix and uterus.
Zygote: The cell resulting after fertilization of the oocyte by the sperm. Visible in the laboratory 1 day after egg retrieval.
Zygote intrafallopian transfer (ZIFT): A process in which zygotes are transferred to the fallopian tube at the pronuclear stage (before cell division takes place).
Educational Overview
Endometriosis Facts
Medication Instructions


Asthma is a condition where your airways swell, narrow, and produce excess mucus. More than likely, you know someone who suffers from asthma! The National Center for Health Statistics estimates that 18.4 million adults have asthma in America. In order to care for yourself or a loved one with asthma properly, make sure you understand what asthma looks like, how it can be treated, and where you can get that treatment.
Asthma symptoms vary from person to person. To manage your health properly, take note of your own symptoms to ensure you can recognize when your asthma begins to flare up.
When asthma symptoms suddenly escalate beyond their usual severity, it is called an "asthma attack." These events need to be treated seriously. Do not wait to see if an asthma attack will resolve with time. Severe asthma attacks can be life threatening.
Coughing and wheezing may not necessarily worsen based on the severity of the asthma attack. In fact, some extreme cases of asthma attacks do not involve any wheezing or coughing, since your lungs may not get enough air to do either of these things.
Asthma attacks can be fatal. According to the Centers for Disease Control and Prevention, asthma attacks resulted in 3,651 deaths in 2014. While children experience asthma attacks with slightly more frequency than adults, you will not outgrow the risk that asthma presents. As the chart below shows, older adults die from asthma attacks significantly more than children. In fact, asthma is rarely a sudden, unexpected killer. Usually, if someone dies from asthma, it is because of gradually worsening symptoms over time.
Asthma can flair up for a variety of reasons. The symptoms are similar, but the inciting event triggering the asthma can differ. Identifying what causes your asthma symptoms to flare up is incredibly important for your well-being. In order to treat your condition properly, you and your doctor need to know what is causing your airways to swell.
Around 50 million Americans live with indoor and outdoor allergies according to the Asthma and Allergy Foundation of America. Allergies and asthma often occur together. In fact, allergy-induced asthma is the most common type of asthma. 60 percent of people with asthma suffer from allergy-induced asthma. It is easy to see the similarities. Both are respiratory conditions with similar symptoms.
Allergens – like pollens, spores, dust mites, mold, or pet dander – cause the airways of the lungs to become inflamed and swollen.
Under normal circumstances, people breath through their nose. Air is warmed and moistened in the nasal cavity. When exercising, however, you may rely on breathing through your mouth. This means your lungs are in contact with colder, drier air than usual.
Exercise-induced asthma occurs when, after 5 to 20 minutes, this temperature and humidity difference causes your airways to narrow. Restricted breathing results in coughing, wheezing, fatigue, and/or a tightening of the chest.
People with asthma often experience asthma symptoms when exerting themselves physically. However, there are also individuals who do not otherwise experience asthma that suffer symptoms when exercising.
Occupational asthma, as the name implies, is a result of your workplace. In some cases, a work environment inflames a pre-existing. Other times, the workplace causes a new problem to develop.
There are three general causes of work-related asthma. First, a work environment can have allergens that a person may not otherwise be exposed to, resulting in their asthma flaring up. Second, some work-places contain irritants that can trigger asthma, such as a coworker smoking. Finally, in the case of a reaction, sometimes a body's natural chemicals – like histamines – can build up and cause an asthma attack.
When you suffer from occupational asthma, your symptoms will be worse on days that you work and you will improve during your time off. In addition to the normal asthma symptoms, you may also experience eye irritation, runny nose, and/or nasal congestion.
The Occupational Safety and Health Administration set guidelines determining acceptable levels of exposure to substances known to cause occupational asthma. If exposure to certain triggers is unavoidable in your career, speak with your healthcare provider to determine the best way to approach your employer regarding precautions or alternative workplace set-ups.
Asthma is a chronic condition. Often, asthma changes as people age. Some individuals will see their symptoms lesson; however, others will find them worsening with time. Ultimately, there is no cure, only treatments.
Knowing yourself and your body is the most important part of treating your asthma. Once you and your doctor identify what causes your asthma to flare up, you can modify your environment and habits to help prevent asthma attacks before they start.
For your safety, make sure to create an asthma action plan with your doctor to ensure you and your family understand the appropriate action for treating your asthma, whether it is a little flare or a serious attack.
Asthma may be common, but that does not mean it is alright to ignore it. Call us at (210) 921-6600 to get more information about asthma or asthma-related symptoms. If you or your loved one are experiencing an asthma attack, hurry to the nearest Gonzaba Urgent Care location for assistance immediately.


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The Rise Youth Development Program
"They gave me the opportunity to develop my potential. Limits only exist in your mind."
—Brenda Sactic, program graduate
Only 10% of poor kids in Guatemala graduate from high school. With a Rise scholarship, 80% do.
53% of graduates are helping to pay for their younger siblings' education.
It Takes 12 Years
In Guatemala it takes 12 years of education to support a two-person family above the poverty line, but 90% of poor kids never reach that milestone. Many come from regions where individuals typically complete fewer than two years of schooling. Families often live on less than $4 a day and can neither afford the direct cost of attending school (tuition and fees) nor the opportunity cost of keeping children in school when they could be working and contributing to the family's income.
In addition to economic challenges, students face many other pressures to drop out including alcoholism, gangs, teen pregnancy, abuse, and a lack of support from their families.
Reaching Graduation
Each year, with the help of sponsors, the GLP provides full academic scholarships to hundreds of indigenous Maya students in impoverished communities throughout Guatemala. In addition to removing economic barriers to education, the Rise Program also wraps students in a support system to help them overcome the pressure to drop out of school:
Sponsors' investment in students' education inspires them to persevere.
Program staff provide social work, academic support, and guidance to see students through to graduation.
Teacher guides serve as mentors and keep a watchful eye on struggling students.
Peer mentoring builds a support system among students.
Home visits involve parents in their children's success.
Becoming Leaders
The youth development component of the Rise Youth Development Program involves students in leadership, professional, and life skills training.
Broadening Worldviews: Workshops on topics like entrepreneurship, women's rights, and teamwork help students expand their worldviews and overcome obstacles to achieving their dreams.
Career Readiness: By visiting local businesses and meeting role models in different careers, students explore the possibilities for their own future.
Giving Back: By planning and executing their own community service projects, students learn leadership skills and develop a spirit of service.
The Rise Program achieves sustainability by transforming the lives of indigenous young people who then contribute to the development of their entire country. Currently, 53% of program graduates are helping to pay for their younger siblings' education—breaking the cycle of poverty for more young people in their own generation.
Samuel Buc, former Coordinator of the Rise Program, put it this way: "I believe that these students will be the ones who change Guatemala as they assume roles as professionals, business owners, and fathers and mothers, and that they will be the first of many more generations with better opportunities and a solid foundation of values."
info@guatemalaliteracy.org
2300 Montana Ave, Suite 301
The GLP is a network of Rotarians and CoEd that improves education for underserved students in Guatemala. It is coordinated by the Rotary eClub of Ohio Pathways (D-6600).


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Robert Muller
Dr. Martin Luther King, Jr. Celebration: Free Admission Day
Monday, January 21, 2019 - 10:00am to 5:30pm
Music was an integral part to the Civil Rights Movement, and musicians often stood alongside Dr. King during many of his appearances in the name of racial justice. From 2018 Inductees Nina Simone and Sister Rosetta Tharpe to the Freedom Singers, Mahalia Jackson, Bob Dylan, Joan Baez, and Sam Cooke, musicians have regularly played a role in advocating for social change.
Throughout the day, visitors can enjoy live performances, an art demonstration, education programs, and family activities that highlight how people have used music to find their voice and create a sense of community. The event will be emceed and DJ'd by Jason Walker. The Rock Hall's many exhibits, including its featured Stay Tuned: Rock on TV, showcase how artists have used popular music to communicate ideas and incite social change.
NOTE: Coat Check will not be available on Monday, January 21, 2019.
Service in the spirit of Dr. King, the Rock Hall will also take donations of hats, scarves, gloves and other cold weather clothes to benefit Clevelanders in need.
SCHEDULE OF EVENTS (subject to change)
Foster Theater (Level 4)
10:15 a.m. FILM: STANDING IN THE SHADOWS OF MOTOWN (Rated PG, 1 hr 56 minutes)
An evocative profile of Motown's studio musicians known as the Funk Brothers, the house band that backed The Temptations, The Supremes, The Miracles, the Four Tops, Gladys Knight & the Pips, Marvin Gaye, Stevie Wonder, and Mary Wells, among others.
12:30 p.m. ALBUM SPOTLIGHT: JANET JACKSON'S CONTROL
Listen to 2019 Rock & Roll Hall of Fame Inductee Janet Jackson's classic 1986 album Control like never before! Rock Hall experts introduce the album and audience members are encouraged to share their Janet Jackson memories.
1:30 p.m. CLEVELAND IS THE CITY: A FAMILY EDUCATIONAL SESSION
Explore the history of soul and rhythm and blues music in Cleveland, one of the cities that gave birth to rock and roll music. Listen to artists from Screamin' Jay Hawkins to Tracy Chapman to Kid Cudi who helped create Cleveland's culture.
2:30 p.m. ROCK & ROLL AND THE CIVIL RIGHTS MOVEMENT: A FAMILY EDUCATIONAL SESSION
Learn how a range of artists, from Mahalia Jackson and Sam Cooke to Berry Gordy at Motown and rock & roll pioneer Fats Domino created a popular music that empowered African Americans to take their rightful place in American society.
3:30 p.m. FILM: STANDING IN THE SHADOWS OF MOTOWN (Rated PG, 1 hr 56 minutes)
Klipsch Audio Main Stage (Level 1)
10:30 a.m. PERFORMANCE BY RAINEY INSTITUTE DANCE TEAM
Dance Mastery at Rainey provides access and oppurtunities in the discipline of dance to youth from grades 3-8.
11:30 a.m. PERFORMANCE BY THE DISTINGUISHED GENLTEMEN OF THE SPOKEN WORD
A powerful performance arts and spoken word group comprised of adolescent males (12-19) from Cleveland communities.
1:00 p.m. PERFORMANCE BY JUL BIG GREEN
A soul rock fusion band from Cleveland.
3:00 p.m. PERFORMANCE BY MOURNING [A] BLKSTAR
A local self-described DIY Afrofuturist soul group that's received national attention and acclaim for their music, which communicates their vision and love for the community while collectively creating greater opportunities to create and share.
Voinovich Atrium (Level 0)
11 a.m.-4 p.m. FAMILY ACTIVITIES
Enjoy crafts and activities such as creating your own protest signs and adding to the Rock Hall's dream wall.
Forest City Theater, Main Exhibit Hall (Level 0)
ALL DAY - Dr. King's "I Have a Dream" speech (22 minute film loop)


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Q: Conditional probability of a variable conditioned by more than one variable I'm learning statistics and I can find any example of how to calculate this  $P(x|y,z)$.
I think is simply than that:
$$P(x|y,z) = \frac{P(x,y,z)}{P(y,z)}$$
Is that correct?
I will appreciate a suggestion for a good book of probability.

A: I assume you agree that $Pr(A \cap B) = Pr(A|B)Pr(B)$ for events $A$ and $B$.
First, we can write your $P(x,y,z)$ in a more standard way as $Pr(x \cap y \cap z)$.
Then we can re-bracket, making use of the associativity of set intersection, so that we have $Pr(x \cap (y \cap z))$. From this, using the above rule, it follows that $Pr(x \cap y \cap z) = Pr(x|y \cap z)Pr(y \cap z)$.
Rearrange this equation to obtain $$Pr(x|y \cap z) = \frac{Pr(x \cap y \cap z)}{Pr(y \cap z)}$$ as you had. So, yes—you are correct.
I hope this helps your intuition about extending this idea to as many events as you like.

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