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Unknown mistakes
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Donnie Darko (2001)
Directed by: Richard Kelly
Starring: Daveigh Chase, Drew Barrymore, Holmes Osborne, Jake Gyllenhaal, James Duval, Maggie Gyllenhaal, Mary McDonnell, Patrick Swayze
Genres: Drama, Mystery, Sci-fi, Thriller
Suggested corrections Significant dates Titles starting with D
Question: What is the music track that plays during the scene where Donnie is talking to Frank in the bathroom inter-cut with the teacher complaining about the book being read to the students?
Dra9onBorn117
Chosen answer: Song: Manipulated Living. Composer: Michael Andrews.
Question: In the part of the movie when the science teacher and Drew Barrymore are sitting in the staff room, what does their conversation mean? Science teacher says, "Donnie Darko." and Drew Barrymore says, "I know." What significant plot does this have?
Answer: According to the audio commentary, "they're being manipulated and they are aware that something is going on with this kid and are laughing about it." Director's commentary is very interesting.
Question: What was the message that Dr. Thurman was trying to say to Rose? She said she needs to talk to Rose for some reason. Why?
Answer: I think I can recall enough to answer. Dr. Thurman's most recent therapy session with Donnie resulted in her assessment that Donnie's condition had quickly deteriorated and he was (or might be) in imminent danger of hurting himself or engaging in some type of dangerous or violent or self-destructive behavior (or doing something bizarre, such as attempting time travel). Under hypnosis, Donnie admitted to Dr. Thurman that he "did it again" (flooded the school), burned down Cunningham's house because he had "kiddy porn", that "Frank" was going to kill someone, and the "sky was going to open up"; Donnie was also crying. Dr. Thurman wanted Rose to be aware and, undoubtedly, keep a close eye on Donnie and inform her immediately of any changes or behaviors of concern. Why Dr. Thurman would leave a telephone message under these circumstances and fail to immediately intervene or take preventive measures does not speak highly of her competence. I think showing the party before Dr. Thurman leaving the message left some viewers in the dark.
Question: Couldn't the events of the movie have been avoided if Frank just let Donnie get hit by the jet engine and die from the beginning instead of waking him up and taking him out of his room?
sccrkeepa00
Chosen answer: In short: no. Because of the films themes of wormholes, time travel, alternative dimensions/parallel universes and meta-physics the events of the film had to happen the way the did or else they wouldn't have happened at all! It's very difficult to wrap your head around but it's one of the many many paradoxes caused by time travel (cause and effect becoming effect and cause).
Sanguis
Question: If Donnie was supposed to die anyway, why did Frank call him out of his house at the beginning? Please don't say it was his schizophrenia and the fact that he is "prone to wander at night", because it IS Frank who calls him out, he doesn't get up on his own.
Answer: Frank calls Donnie out because the airplane engine has fallen through a portal into an alternate universe, and at some point during his sleepwalk Frank guides Donnie through another portal to move him to the alternate universe (from the movie theatre we know that Frank can make portals at will). Frank appoints Donnie to be the guardian of the engine and make sure it falls through the alternate universe's portal into the original universe. Donnie cannot be allowed to die until the engine is escorted into the second portal, but if he dies before then the engine never reaches the second portal and remains in the alternate universe, causing the original universe to unravel. Once he and the engine return, he must die because his experiences of the alternate universe predict the future, potentially causing paradoxes.
Question: It might just be in my head, but, at the end, when Gretchen talks to Donnie's mom, it seems like they knew each other or their 'conversation' had a deeper meaning. Does it really?
Flamedeiros
Chosen answer: The characters who died in the first running of time are known as the "manipulated dead" who were required to die to fix the hole in time. So although when the hole is closed at the end and the characters didn't die because time has been altered, they can't remember anything that happened, but supposedly have some kind of recognition for each other as the events were like a dream to them.
Question: When Donnie is talking to his teacher, he says that he can't continue the conversation because he could lose his job. Why? Does this have anything significant to do with the plot?
Answer: Donnie is attending a private religious school (thus the uniforms and the fact that a former teacher, Ms. Sparrow, was a nun) and if his science teacher continued his explanation he would be teaching against the conservative religious curriculum.
Question: The scene where they are watching a Washington Redskins game on TV, shows Doug Williams throwing a pass in slow motion and it looks like they are losing the game. In the timeline this game is played before October 18, 1988. The only game which he played in and lost that year was against the N.Y. Giants on Monday night to start the season so I could not place the date or opponent of the game that was airing in the scene. Who/when was it?
Answer: Several key factors in determining which game it was. The commentator said, in regards to the Redskins it's been a disappointing "night for the Super Bowl champions", meaning this game took place in 1989, since the Redskins won the Super Bowl in '88. Additionally, he said "Mark Rypien has some big shoes to fill." Rypien took over the starting QB role in '89 over the Super Bowl MVP Williams. The slow motion shot was probably a Super Bowl highlight. Given this was a night game with the Redskins missing a field goal, it was the Nov 20, 1989 game vs Denver Broncos where the Redskins lost 10-14.
Question: What film/text/person does Kitty Farmer confuse with Graham Greene when she replies to Rose Darko: 'I think we've all seen Bonanza.'?
Answer: Lorne Greene was the star of Bonanza which aired regularly from 1959 until 1973. He played Ben Cartwright, the wise widowed father of Adam, Hoss, and Little Joe.
Myridon
Question: Does anyone have any thoughts on why at the very end of the credits, the national anthem is played? I found it interesting, i just wonder if someone else has any theories on how this ties in with the movie.
musikkjunkkiee
Chosen answer: Back in the 80's most channels went off the air at a certain time at night. Right before the channel went off it would play the national anthem then go to static. This is an obvious homage to the 80's (twice the TV Donnie's dad is watching is showing static, indictating that the channel had gone off the air).
Question: What is the creepy opera-esque music playing when Donnie sees Frank in the movie theatre called? I can't find it in the soundtrack.
Answer: The track is called "For Whom The Bell Tolls" and it's composed by Steve Baker and sung by Carmen Daye. You're right, it's not on the soundtrack but it can be found through a search engine.
Question: After watching "Donnie Darko" I watched another film which also featured a character identical to Frank. He too appeared in the dreams of the lead role and had all the traits of Frank. I am pretty sure it was not the film "Harvey", as I do not believe it was a film as old as that. Can anyone help me identify what the other film was?
Answer: I believe this film may have been 'Sexy beast' starring Ray Winstone. It's a British film, and is even listed on the IMDb as similar to Donnie Darko in this sense. In 'Sexy Beast' a human height sized bunny rabbit stalks the dreams of the lead character, played by Ray.
Question: What was the significance of Frank wearing the rabbit suit? Was it because the face was supposed to stick in Donnie's mind so he'd remember what he had to do? I can't think of any logical reason why he'd have to wear the suit to accomplish his mission.
Answer: According to the DVD special features, people who die in the alternate universe (the Manipulated Dead) have more power and self-awareness than those who live throughout. The supernatural force that appoints Donnie to end the alternate universe adopts Frank's face because a) he wants a form that Donnie can interact with and b) as a Manipulated Dead Frank has more understanding of what is going on and maybe wants to help. The costume is necessary because it's an essential part of Frank's character as a dead person - it's what he was wearing when he died - and also because it's so alien Donnie will understand that he's dealing with things beyond normal ken.
Question: At the end, when Mad World is playing and it shows the FAA people talking, is one of them Jon Stewart? He isn't listed in the credits, but I am quite sure of it.
Answer: It's not Jon Stewart. I saw the guy you were talking about but you can see his chin is a bit longer than Jon Stewart. Added to that he is not credited or uncredited on the film's listing on IMDB.
Lummie
Question: In the very last scene (I have only seen the original version, not the Director's cut), a crowd is gathered outside the Darko house and Gretchen comes along on a bike and talks to this little blond kid. When she asks him "What happened?", if you listen closely you will realize that the kid's response is not exactly standard English. It sounds, in fact, like complete gibberish, or just possibly something meaningful in a non-English language. What exactly is that kid saying, and what is its significance?
Answer: It is, in fact, English. He says "Got smushed by a jet engine".
Question: I didn't understand where the engine that killed Donnie at the end of the movie came from. This plane belonged to the tangent universe right? So when Donnie gets back to his room where all has started, he gets back to the real world. Is this engine a residue from the tangent universe? Because they say in the movie that no plane has lost an engine in the real universe.
Answer: Yes the engine has come from the tangent universe or the alternate future so to speak. The reason they have trouble finding the engine is because it hasn't happened yet and it has entered a corruption in the universe. With that in mind the key difference from the start of the film to the end is that Donnie managed to send the engine through the wormhole as opposed to the engine entering the corruption at the start of the film.
Question: I understand that Frank is part of the manipulated dead and I also understand that he does not travel through time, but rather manipulates it as it happens. This leads me to ask, how was it possible for Frank to guide Donnie before Donnie kills him? Is this implying that the loop has happens over and over until Donnie gets it 'right' and sacrifices himself?
Answer: No, the timeline is not a loop. Frank's death is just bound to happen and he is supposed to make sure Donnie kills him, after accidentally killing the girl. That is the "trap" as they call it. To make sure that Donnie is forced to fix the universe and saves everyone.
Question: In the short scenes following Donnie's death, many of the characters are shown reacting to his death, I think. Why is Patrick Swayze crying? Does it have something to do with his regret of participating in child pornography?
Answer: It is either from the regret of participating in child pornography or guilt from having thoughts about it in the first place. (Since Donnie's Death 'reversed' many events, Swayze's character may have never actually made the room, etc.)
Question: Where did that engine comes from which causes Donnie's death? If he had returned the engine to the PU than how could the plane crash when his sister and mother were still in their room? And Just Before Donnie died why did he laugh? Was it because of his awareness of what's gonna happen in the future?
Towhid Chowdhury Faiaz
Chosen answer: His mother and sister didn't need to be on the plane for it to crash and the engine traveled back in time regardless of whether Donnie was in his room or not. But by staying in his room to die, Donnie saved his mother's and sister's lives since they cancelled their trip on account of his death, and prevented many other deaths. The one downside seems to be that the child pornographer would remain uncaught, but 10 days after the PU is restored, he commits suicide by shooting himself in the head.
Question: In the Director's Cut, there is a scene where Drew Barrymore tells the students they will be reading Watership Down instead of The Destructors but there have been copies of The Destructors reserved at the Mall. She then turns to Donnie and says "perhaps you and Frank could read it together". Does she know about Frank and if not what does she mean by this?
Answer: There is a cut scene in which Donnie reads a poem he wrote in front of the class and he mentions Frank. Drew asks who Frank is and he states he's a 6 foot tall bunny rabbit. That is how Drew knows about Frank and since Watership Down's main characters are rabbits, this reference to Frank is appropriate.
More for Donnie Darko
Visible crew/equipment: When Donnie and his Dad are in the car, talking, prior to nearly hitting Grandma Death, in the window behind Donnie's Dad is the reflection of a vehicle which says "Darko" clearly on it. (00:21:00)
More mistakes in Donnie Darko
Gretchen: You're weird.
Donnie: Sorry.
Gretchen: No, that was a compliment.
More quotes from Donnie Darko
Trivia: When Donnie is about to enter the car with Gretchen near the end of the film, he clutches at his stomach as if in pain, and we see Frank touch his eye after Donnie dies. Both these moments foreshadow pain: a deleted scene of Donnie's death shows a pole impaling his stomach right where he clutched it. And Donnie shoots Frank in the eye.
More trivia for Donnie Darko
Mistake & trivia booksMost popular pagesBest movie mistakesBest mistake picturesBest comedy movie quotesMovies with the most mistakesNew this monthUnknown mistakesGrease questionsFamily Guy mistakesBiggest Bond movie mistakesBabel endingGoodfellas triviaGal Gadot movies & TV showsStep Brothers quotesThe Notebook plotThe SpongeBob Squarepants Movie mistake pictureMore for Donnie Darko
In the class with the Lifeline exercises, the "L" on the word "LOVE" changes how it is drawn about 4 or 5 times between shots.
Gretchen: You're weird. Donnie: Sorry. Gretchen: No, that was a compliment.
Frank tells Donnie that the world will end in 28 days, 6 hours, 42 minutes and 12 seconds. The jet engine is shown landing in Donnie's room, killing him, exactly one hour, 42 minutes and 12 seconds into the movie.


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Last Updated: Thursday, 11 September, 2003, 08:20 GMT 09:20 UK
Music firms claim public backing
The RIAA says it is only after "substantial" offenders
The US music industry has said a slim majority of the public supports its campaign against online song-swappers.
The Recording Industry Association of America (RIAA) released a survey showing that 52% backed the move.
It questioned 800 people for the poll, two days before targeting 261 individuals for distributing songs on the internet without permission.
The RIAA says piracy is hitting sales, but critics say CD prices are too high.
In the survey, 52% said they supported the music industry's position, while 21% said they did not support it.
"These results show that our message is definitely getting through," said Mitch Bainwol, the RIAA's chairman and chief executive.
Legal troubles
However, the association is facing a barrage of criticism for taking ordinary citizens to court.
Many defendants named in the lawsuits said they were not aware they were breaking the law and were first informed of their legal troubles by the media.
One person named in the lawsuits was Jeani Ziering of Manhattan, New York.
Her 26-year-old son - who said he was living on welfare benefits and only had $100 in his bank account - told the Reuters news agency it was him who had been downloading tracks using the internet.
"I just heard about it from another reporter. I haven't been doing it in a while and took the songs off my computer," said the son, who was not named by Reuters.
"I'm just listening to the music I already own. I took it off my hard drive because it was taking up too much room on my computer."
Under copyright law, defendants could face penalties of up to $150,000 (£94,000) per song, but settlements are expected.
Pete Fader, a marketing professor from the University of Pennsylvania, said the lawsuits were "a terrible mistake".
"I think there's lot of ways to stop piracy and encourage more positive behaviour," he said.
The RIAA insists it is only going after those that download "substantial amounts" of copyrighted songs.
Download wars
Napster boss on life after piracy and battling the iPod
US analogue switch-off in 2009
Sky launches film download site
Download plan for deleted tracks
Breakfast shows top podcasts
Court rules against 'music pirates'
ASK THE INDUSTRY
Hollywood's answers
Q&A: Supreme Court ruling
Q&A: Film downloading
Q&A: Music swapping
Q&A: DVD piracy
Recording Industry Association of America

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Health Accreditation Gold Rank
Global Recognition (Forbes)
International School Award for Gurukul Global School
Gurukul Global School experienced a state of euphoria and ecstasy as it received the InTERNATIONAL SCHOOL AWARD from the International Body British Council. iSA as it is popularly called is a benchmarking scheme that accredits schools as having an outstanding level of support for:
* Nurturing global citizenship in young people
* Enriching teaching and learning.
* The school embarked on its ISA journey in June 2017 with making of Action Plans for the 7 projects, all infused with international dimension. The school partnered with schools from Nepal and Afghanistan on a varied genre of projects Like Diseases of India-south Africa, water conservation in India- Germany,
Cultural exchange between India and Nepal, global warming between India and afghanistN to name just a few. The projects gave a deep understanding of these topics with respect to how these problems were tackled at the global level and what solutions were provided to these glaring problems plaguing the world today. All In All it was a great learning experience for all he students and teachers as they got immense exposure to the global outlook!!


The Samurai, the elite japanese swordsmen, had a very specific code that they lived by called the Bushidō . There was a saying about what was important when training to be a Samurai; Zen 7 and Ken 3. Zen is spirit and Ken is sword.
It means that 70% of your training needs to happen on the inside, and 30% on the outside. That is, 70% is about spirit, character, and 30% about technique. I'd wager if you would ask any Japanese business man today which they would prefer, a rock solid fiery spirit, or a new management technique, they will take the first. Yet, think about the type of training that you often receive in business today, how is it weighted?
Get skin in the game, person first, technique second.


like a meadow in my hair.
lick it clean from my thumb.
The greatest of pleasures; a hunger satisfied. Particularly in the middle of the night or a dream.
Never was peanut butter so honored.
The words aren't flowing too freely, but I'm hoping to get something written!
meadow in your hair and mozart.how fab!!
Delicious... I love peanut butter on toast, sadly it doesn't look good on my hips though.
lick it clean from my thumb."
Love this too: "ruthless and without tact"
You get it, don't you Flip?
and the peanut butter of course.
Best time for peanut butter, this poem is finger lickin' good!
Love a mid-night-snack ! thanks.
Oh my! This is so wonderful ... it had the opposite effect on me.
This relates to Lady M, more than myself. Maybe it's a female thing!
A great scene in your words.
Berkshires are a breed of pig...it was a weird dream I had...they were using my finger towels!
I'm listening to Diana Krall whilst reading this. Excellent match.
Thanks to Little Nell for asking my question first. I thought they were a mountain range, and I was sitting here trying to figure out what mountains could possibly have to do with a finger towel, and how that translated into peanut butter.
Odd fact: I must have some sort of esophagus issue, because peanut butter gives me heartburn. Thus, sadly, I can never eat it late at night because the lying back down is too painful. I can only eat peanut butter in small doses, in the middle of the day, followed by copious amounts of ice cold milk.
Happily, licking fingers at 3AM is perfectly fine. Preferably not my own.
I would, but my husband refuses to sleep with anyone but me.
Peanut butter as metaphor ~~~ how delightful.
At first I'm thinking, peanut butter straight from the jar, nothing so good. But I'm rereading the poem, and finding so much more!
Thanks for the walk through this meadow in your hair, Tess !
Peanut butter directly from the jar and eaten with a spoon! Yes, a great snack anytime day or night. Great poem!
Peanut butter cravings satisfied at that late hour. What other choice at midnight than in the shadows of faint lights far from civilization! Nicely Tess!
I was thinking of the mountain range and couldn't make sense of the first lines. Thanks, Nell, for asking.
Peanut butter is always a good cure.
Every line of this is just perfect! I love the meadow in your hair and "I crave often and sticky." What a yummy poem!
A singing meadow...a glorious piece!


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Q: The following dependencies were not resolvable. See your build.gradle file for details I am creating an app for my school and the first activity is just a screen that says welcome and stuff. Then there's a button that says Continue and when they click on it, it is supposed to take them to a log in screen and from there they can log in. So i right clicked on the folder main on android studio and selected new -> activity ->login activity i put in the info for the name and its package name and when i clicked finish that error appeared. The following dependencies were not resolvable. See your build.gradle file for details.
    - com.google.android.gms:play-services:4.0.30.

A: Install the Google Repository from the SDK manager.

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Joe Rogan Reacts To DMT Alien. Joe Rogan's mind is blown by hyperdimensional DMT entity, Zylok. Joe discusses his psychedelic experiences and consciousness/soul philosophies with an extraterrestrial.
Zylok discusses the foundation of Hyperdimensional entanglement, and how that relates to a crystallized portions consciousness. Hyperdimensional Templates Of Existence can assist in the understanding of Astral Projection, OBE's (out of body experiences) and Disembodied states of consciousness.
The nature of existence is simultaneously quintessential and truly bizarre. Our state of consciousness dictates how we perceive all corporeal and transcendental experiences.


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It's no surprise that Cost is one of the most significant targets of Medicare Value-Based Health Care initiatives, as well as those in the private sector. So it was a real surprise last month to learn that CMS would delay weighing Cost as a component of MACRA MIPS total scoring. Equally significant is the CMS plan to scrap the ten episodic cost measures that were part of the cost calculation for provider groups in exchange for new, "to be determined" versions.
Does this retreat from Cost and episodic costs calculation signal a big shift in the direction of Medicare Value-Based Health Care? In particular, will Bundled Payments based on episodes of care, which have been a major proposed solution to realigning incentives for payments to specialists, be abandoned? Apparently so, according to Dr. Tom Price, Director of Health and Human Services.
An orthopedic surgeon, Dr. Price has previously spoken out against the Comprehensive Care for Joint Replacement (CJR) model, which has been mandatory in dozens of locations across the country. In September 2016, Dr. Price contended that the CMS Innovation Center is "experimenting with Americans' health" by making the CJR model mandatory. Removal of the MIPS episodic cost metrics (which include hip and knee procedures) is consistent with this narrative.
Cost will count for 30 percent of the total MIPS score in 2019, and new episodes are in development. Regardless of how CMS includes episodes in its cost calculations, however, providers should not be quick to abandon them. Why? Regardless of whether the FFS MIPS Model remains or Medicare transitions to APMs and Medicare Advantage, intermediary ACOs and health plans will likely opt for bundled and episodic payments for most specialty care.
Let's start with outcomes. A study published in JAMA indicates that Bundled Payments, which use a pre-determined expenditure for an episode of care, have been successful in lowering episodic costs. In a pool of almost 4,000 patients undergoing a lower extremity joint replacement procedure (the procedures under the microscope in CJR), costs decreased by more than 20 percent over the course of seven years—without impacting patient outcomes. By comparison, expenditures for similar procedures across the country actually increased over the same time period.
Quality reporting on MIPS-like measures.
Number of beneficiaries that may be impacted.
By expanding on the existing Bundled Payments model, an organization has the potential to take control of its own destiny—not to mention the chance to pick up a 5 percent lump sum payment if the project is granted Advanced APM status.
Because ACO quality metrics and cost composites focus heavily on primary care, specialists are faced with a tough decision: Is it better to be left out of an Alternative Payment Model, or to be included, but without the ability to steer? By tracking and evaluating episodic costs, almost every specialty has the opportunity to contribute to a quality initiative, either through the to-be-determined MIPS cost episodes or as an eventual Advanced Alternative Payment Model. This is an excellent opportunity to engage those specialties that have been traditionally left out of Medicare initiatives.
For example, OB/GYN providers have had limited ability to demonstrate performance through PQRS or the Value-Based Payment Modifier, as these programs were driven by Medicare enrollment. Although MIPS does include all payers in quality metrics (unless you're reporting through the CMS Web Interface or through claims), MIPS eligibility is still Medicare-based. However, if your organization is considering an All-Provider APM down the road, analyzing episodes outside of the traditional Medicare population (e.g. childbirth) can bring more specialties into the fold, many of whom are eager to play a more active role in the quality process.
As we saw, the GDP-to-healthcare spending ratio continually demonstrated that fee-for-service was not sustainable. Congress passed one "Doc Fix" after another to prevent cuts, but healthcare spending didn't come down, and it took MACRA to stave off the 21 percent cut that would have been applied through the Sustainable Growth Rate. With MIPS steering towards risk, and the requirement that more and more reimbursement must come through an APM, creating an APM based on episodic costs can meaningfully bring specialists into the fold and cover their costs.
Episodic Payments can help patients proactively budget out-of-pocket costs, which can protect against personal financial catastrophe. They add transparency to a traditionally opaque relationship between dollars spent and quality of care.
Our clients have recognized this, and some have actually posted a fixed cost for an episode. The individual out-of-pocket costs will vary by patient and plan, of course, but the fact that providers are providing this information to be competitive signifies that privatization will not kill Value-Based Health Care. As with any other industry, our clients have recognized that if they can demonstrate that they're able to provide a better product at a lower cost, well-informed customers will seek them out. In this case, the better product is an episode with expected results.
The Episodic Cost model may face an uncertain future through MIPS, but should not be abandoned. An organization committed to lowering cost-per-episode is acting in its own best interests, which are also (as they should be) the best interests of their patients. Both parties can benefit from demonstrable evidence that costs can be decreased without sacrificing outcomes.
Patients will be able to make informed decisions, knowing who has a track record of producing good outcomes, and doing so efficiently. Reducing complications and re-operations should be a great source of pride for everyone in the organization—both providers and administrators—and tying these metrics to reimbursement ensures that those who can produce these results are appropriately rewarded.


ALS can proactively determine any potential processing issues that might be encountered, thereby efficiently defining the optimum testwork program for mining projects.
Importantly, use of this integrated service can preclude the exhaustive testing of unnecessary processes, ultimately saving project time and budget.
The highly-experienced team of mineralogists, metallurgists, and technicians at ALS work collaboratively to provide the highest quality results within fast turnaround times. ALS applies an integrated mineralogical approach using QEMSCAN®, MLA, X-ray diffraction, HyLogger™, and optical microscopy to produce an accurate, quantitative understanding of the mineralogical assemblage and variability within a deposit.
Automated mineralogical analysis using QEMSCAN® and MLA provides accurate, fast, reproducible, quantitative mineralogical analysis of samples and related materials to maximise productivity and efficiency of exploration, process design, optimisation, mining, production, marketing, and rehabilitation processes.
Why XRD and spectral analysis?
X-ray diffraction (XRD) analysis and spectral analysis using the HyLogger™ provide information on the bulk mineralogy of large numbers of samples and are becoming increasingly valuable as an input in geometallurgy programmes. The rapidly generated HyLogger™ data has several benefits including improved objectivity and consistency of core logging and an improved understanding of the 3D models generated during exploration programmes.
ALS mineralogists work hand-in-hand with the ALS metallurgy team to include quantitative automated mineralogy testwork as an integral component of metallurgical testwork programs.


text:
Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors
Mitsuko Okada, David Goldman, Markku Linnoila, Nakao Iwata, Norio Ozaki, John K. Northup
We compared the ability of human 5-HT2C and 5-HT1A receptors to couple to selected G proteins expressed in insect Sf9 cells through simultaneous infection with recombinant baculoviruses. We also examined the coupling of G proteins to these same receptors in membranes derived from the Sf9 cells using in situ reconstitution with purified G proteins. Our data show that unoccupied 5-HT2C and 5-HT1A receptors can attain an activated conformation that is stabilized by interaction with specific G proteins. While high-affinity agonist binding to the 5-HT2C receptor was increased to a greater extent by Gαq than by Gαi2, the high-affinity agonist binding to the 5-HT 1A receptor was preferentially enhanced by Gαi2 coexpression. When the two 5-HT receptors were expressed in cells also expressing G proteins, both 5-HT2C and 5-HT1A receptors appear to activate Gαi2 in preference to Gαq. In contrast, in situ reconstitution data show that 5-HT2C receptors robustly activate Gαq and marginally activate Gαo or Gαi, whereas 5-HT1A receptors only marginally activate Gαq and robustly activate Gαo and Gαi. These results suggest that the overexpression of receptor and potential G-protein coupling partners in Sf9 cells may lead to erroneous conclusions as to the signaling selectivity of receptors.
Receptor, Serotonin, 5-HT1A
Sf9 Cells
Receptor, Serotonin, 5-HT2C
Baculoviridae
Serotonin Receptors
Okada, M., Goldman, D., Linnoila, M., Iwata, N., Ozaki, N., & Northup, J. K. (2004). Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors. Annals of the New York Academy of Sciences, 1025, 570-577. https://doi.org/10.1196/annals.1316.070
Okada, Mitsuko ; Goldman, David ; Linnoila, Markku ; Iwata, Nakao ; Ozaki, Norio ; Northup, John K. / Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors. In: Annals of the New York Academy of Sciences. 2004 ; Vol. 1025. pp. 570-577.
@article{2915eac0211445cea7424f9aba2dcec1,
title = "Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors",
abstract = "We compared the ability of human 5-HT2C and 5-HT1A receptors to couple to selected G proteins expressed in insect Sf9 cells through simultaneous infection with recombinant baculoviruses. We also examined the coupling of G proteins to these same receptors in membranes derived from the Sf9 cells using in situ reconstitution with purified G proteins. Our data show that unoccupied 5-HT2C and 5-HT1A receptors can attain an activated conformation that is stabilized by interaction with specific G proteins. While high-affinity agonist binding to the 5-HT2C receptor was increased to a greater extent by Gαq than by Gαi2, the high-affinity agonist binding to the 5-HT 1A receptor was preferentially enhanced by Gαi2 coexpression. When the two 5-HT receptors were expressed in cells also expressing G proteins, both 5-HT2C and 5-HT1A receptors appear to activate Gαi2 in preference to Gαq. In contrast, in situ reconstitution data show that 5-HT2C receptors robustly activate Gαq and marginally activate Gαo or Gαi, whereas 5-HT1A receptors only marginally activate Gαq and robustly activate Gαo and Gαi. These results suggest that the overexpression of receptor and potential G-protein coupling partners in Sf9 cells may lead to erroneous conclusions as to the signaling selectivity of receptors.",
author = "Mitsuko Okada and David Goldman and Markku Linnoila and Nakao Iwata and Norio Ozaki and Northup, {John K.}",
doi = "10.1196/annals.1316.070",
journal = "Annals of the New York Academy of Sciences",
Okada, M, Goldman, D, Linnoila, M, Iwata, N, Ozaki, N & Northup, JK 2004, 'Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors', Annals of the New York Academy of Sciences, vol. 1025, pp. 570-577. https://doi.org/10.1196/annals.1316.070
Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors. / Okada, Mitsuko; Goldman, David; Linnoila, Markku; Iwata, Nakao; Ozaki, Norio; Northup, John K.
In: Annals of the New York Academy of Sciences, Vol. 1025, 01.01.2004, p. 570-577.
T1 - Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors
AU - Okada, Mitsuko
AU - Goldman, David
AU - Linnoila, Markku
AU - Iwata, Nakao
AU - Ozaki, Norio
AU - Northup, John K.
N2 - We compared the ability of human 5-HT2C and 5-HT1A receptors to couple to selected G proteins expressed in insect Sf9 cells through simultaneous infection with recombinant baculoviruses. We also examined the coupling of G proteins to these same receptors in membranes derived from the Sf9 cells using in situ reconstitution with purified G proteins. Our data show that unoccupied 5-HT2C and 5-HT1A receptors can attain an activated conformation that is stabilized by interaction with specific G proteins. While high-affinity agonist binding to the 5-HT2C receptor was increased to a greater extent by Gαq than by Gαi2, the high-affinity agonist binding to the 5-HT 1A receptor was preferentially enhanced by Gαi2 coexpression. When the two 5-HT receptors were expressed in cells also expressing G proteins, both 5-HT2C and 5-HT1A receptors appear to activate Gαi2 in preference to Gαq. In contrast, in situ reconstitution data show that 5-HT2C receptors robustly activate Gαq and marginally activate Gαo or Gαi, whereas 5-HT1A receptors only marginally activate Gαq and robustly activate Gαo and Gαi. These results suggest that the overexpression of receptor and potential G-protein coupling partners in Sf9 cells may lead to erroneous conclusions as to the signaling selectivity of receptors.
AB - We compared the ability of human 5-HT2C and 5-HT1A receptors to couple to selected G proteins expressed in insect Sf9 cells through simultaneous infection with recombinant baculoviruses. We also examined the coupling of G proteins to these same receptors in membranes derived from the Sf9 cells using in situ reconstitution with purified G proteins. Our data show that unoccupied 5-HT2C and 5-HT1A receptors can attain an activated conformation that is stabilized by interaction with specific G proteins. While high-affinity agonist binding to the 5-HT2C receptor was increased to a greater extent by Gαq than by Gαi2, the high-affinity agonist binding to the 5-HT 1A receptor was preferentially enhanced by Gαi2 coexpression. When the two 5-HT receptors were expressed in cells also expressing G proteins, both 5-HT2C and 5-HT1A receptors appear to activate Gαi2 in preference to Gαq. In contrast, in situ reconstitution data show that 5-HT2C receptors robustly activate Gαq and marginally activate Gαo or Gαi, whereas 5-HT1A receptors only marginally activate Gαq and robustly activate Gαo and Gαi. These results suggest that the overexpression of receptor and potential G-protein coupling partners in Sf9 cells may lead to erroneous conclusions as to the signaling selectivity of receptors.
U2 - 10.1196/annals.1316.070
DO - 10.1196/annals.1316.070
JO - Annals of the New York Academy of Sciences
JF - Annals of the New York Academy of Sciences
Okada M, Goldman D, Linnoila M, Iwata N, Ozaki N, Northup JK. Comparison of G-protein selectivity of human 5-HT2C and 5-HT1A receptors. Annals of the New York Academy of Sciences. 2004 Jan 1;1025:570-577. https://doi.org/10.1196/annals.1316.070
10.1196/annals.1316.070


text:
Das vierte Buch der Makkabäer (oder Über die Selbstherrschaft der Urteilskraft) ist ein apokryphes Buch des Alten Testaments. In vielen orthodoxen Kirchen erscheint es als Anhang zum Alten Testament der Bibel, in westlichen Bibeln ist es dagegen üblicherweise nicht enthalten.

Das Buch ist in 18 Kapitel unterteilt, die aus insgesamt 484 Versen bestehen. Namensgebend sind die Makkabäer, die Anführer eines jüdischen Aufstandes gegen das Seleukidenreich.

Entstehung
Seit Eusebius von Caesarea († 339 oder 340) wurde das Buch unter dem Titel "Über die Selbstherrschaft der Urteilskraft" () Flavius Josephus zugewiesen. Aus inhaltlichen und sprachlichen Gründen ist diese Zuweisung abzulehnen. Vielmehr ist das Buch von einem rhetorisch gebildeten, hellenistischen Diasporajuden im syrischen Antiochien gegen Ende des ersten Jahrhunderts "in einem guten bis vorzüglichen Griechisch abgefasst" worden. Die lateinische Fassung Passio SS. Maccabaeorum (auch Machabaeorum) ist gegen Ende des 4. Jahrhunderts oder zu Beginn des 5. Jahrhunderts in Frankreich entstanden und ist eine sehr freie Wiedergabe der griechischen Vorlage.

Inhalt
Das Buch ist als eine philosophisch-ethische Rede konzipiert. Es versucht, die These zu beweisen, dass die Vernunft Herrscherin über die Triebe ist, und verwendet dazu Beispiele aus dem 2. Makkabäer-Buch (Kap. 6 und 7), weshalb es an die Makkabäerbücher historischen Inhalts angereiht wurde. In Vers 9 des einleitenden Teils heißt es z. B. über Eleasar und die sieben Brüder: "Denn indem diese der Schmerzen bis zum Tod allesamt nicht achteten, zeigten sie, dass die Vernunft über die Triebe Gewalt hat." So mahnt es die Juden zur Treue zum Gesetz.

Das Buch bezieht sich zwar auf Ereignisse der jüdischen Geschichte, ist aber insgesamt sehr stark von der griechischen Populärphilosophie, vor allem der Stoa, geprägt.

Siehe auch
 Liste biblischer Bücher

Literatur
 Heinrich Dörrie: Passio SS Machabaeorum, die antike lateinische Übersetzung des 4. Makkabäerbuches (= Abhandlungen der Gesellschaft der Wissenschaften zu Göttingen. Philologisch-historische Klasse 3. Folge, Nr. 22). Göttingen 1938.
 Hans-Josef Klauck: 4. Makkabäerbuch (= Jüdische Schriften aus hellenistisch-römischer Zeit. Band III/6). Gütersloh 1989, ISBN 3-579-03936-9.

Weblinks

Einzelnachweise

Apokryphe Schrift des Alten Testaments
Flavius Josephus

redpajama_set_name: RedPajamaWikipedia


I was asked a thought-provoking question in our parenting class last year, and as the new school year gets fully underway, it keeps coming back to me.
What is your one hope for your child/children? You only get one thing. Nothing more.
My first thought was, 'to go to heaven.' So, on one side of a note card we all wrote down that one wish. On the back side of the note card we wrote all of the things we and our kids are involved in on a daily or weekly basis.
I am quite certain that my list looked much like many of yours would. Work. School. Church. Baseball. Lake. College football. Homework. Orthodontist appointments. Haircuts. Grocery shopping. Laundry. You get the picture.
Now, this is where the front and back of the card connect. And, it really gets interesting.
How are the things you are doing every day, impacting that hope, wish or desire for your children's life? Wow.
Often times the two don't even connect. In fact, many times they conflict with one another. Ugh.
If only every day I could keep my mind focused on the ultimate goal rather than the momentary desires.
If every day I could focus on the end result rather than the immediate result.
If only I could keep my perspective on things eternal.
What was your first thought when you read the question? Think about it.
Some might say success. Some might say popularity. Some might say good health. Some might say adventure. The list goes on and on.
The one thing I realized is that there is nothing on this earth that we could wish for our children that is lasting.
All of those things are just that. Things.
They can come and go. They might only last for a brief season of life. They might even eventually bring disappointment. They might come with a cost.
Eternal things are just that. Everlasting. Forever.
As we all attempt to settle in the normal of the school year with all of its many activities, can we try to encourage each other to focus on things eternal?
Maybe this means adding prayer time every morning to our hectic routine. Maybe it means setting aside just one night a week that as a family we sit down together and read a few verses in His word for encouragement. Or, perhaps we could come up with a fun game with prizes to encourage our kiddos to memorize a verse each week. Better yet, having some conversations about the tough subjects and sad situations our country is facing.
Whatever it is, intentionally try to put God's plan into our every day lives. Not just on Sunday. Or, when there are no other conflicts. Ask God to provide the plan and sit back and watch Him work. I know He can do more than we ask or imagine if we just ask.
Did you read that? When we take the time to share His word with our families, it always produces fruit. It will accomplish what He wants and it will prosper. I love the final part – you will live in joy and peace. Isn't that what most of us are searching for in our day-to-day lives? Joy & Peace.
Yes, by being intentional and having a plan, we may need to say no to some other things. And, that is okay. Saying no to make more time for God and your family is always a good thing. It's an eternal thing. And, yes, your children will be blessed by spending more time in His presence.
Can we really sit back and take the time to consider how each plan and appointment will impact our eternal goals for our family or children?
Will we miss our family night in His word if we say yes to dinner with friends? If so, we might need to ask them to plan for another night.
Prioritizing and planning is what is necessary for all of us. We all lead busy lives, and I confess, most days my eternal plans for the day don't make the hand-written-to-do list. If they did, I would probably be more apt to remember.
Maybe that is really the key ~ putting our eternal checklist for our families at the top of our to-do list every day!
I long to be intentional with my time and my family. I am tired of chasing rabbits just because everyone else is. I want to chase Jesus instead.
I am tired of chasing rabbits just because everyone else is. I want to chase Jesus instead.
I want my family to know that He is all that matters. And, yes, if He is all that matters, then His people have to matter. All of them. Every. Single. One.
All my activities are for naught if my family doesn't come to know Him and love Him more because of me.
Does the way we spend our time really impact our lives and the lives of those we love for eternity?
Is the front of our card with our one hope for our child/children really in line with our day-to-day activities?
Maybe you don't have children, or your children are grown, if so, what is your one hope for your life and the lives of those you love? Does the front and back of your card line up with that hope?
If not today, all is not lost. Just remember, sweet friends, He is able to change all of our plans and priorities to bring Him glory. All we need to do is ask for His guidance and help. He loves to give wisdom. And, gives it generously to all. Thank goodness!
And, yes, we can trust, if we add Him to the top of our to-do list, He will do just that!
Well said! I love your heart and enthusiasm Jennifer!!!
Thank you, Kelli. I am grateful for you and your husband! Both of you are great examples to so many.


text:
Inside Thirteen
10 Fun Facts on Voting History
Winter Shanck | September 21, 2016
We've scoured the continent and the ages to highlight some unusual and fun facts about voting history in the United States. Learn more about voting and civic responsibility at the National Voter Registration Day event, September 27, being held at WNET Tisch Studios.
Fun Fact #1: George Washington Bought Drinks on Election Day
Painting of George Washington by John Trumbull (1756–1843). who served in the Continental Army under General Washington. Oil on canvas, 12′ x 18′. Commissioned 1817. Image courtesy Joye~/Flickr
In 1758, George Washington, then a young candidate for the Virginia House of Burgesses— the first legislative assembly of elected representatives in North America — bought a huge round of drinks on Election Day. Washington spent his entire campaign budget — 50 pounds — on 160 gallons of liquor served to 391 voters. The custom of buying votes with booze was one of the English traditions imported to the American colony. Washington also was following a Virginia tradition in which barrels of liquor were rolled to courthouse lawns and polling places on Election Day.
Reconstruction of Chamber of the House of Burgesses in the Capitol at Williamsburg, VA. Photo by Frances Benjamin Johnston, ca. 1930-1939.
Fun Fact #2: Weather and Harvest dictated Election Timing
Briarcliff Farm, James Stillman's property in Briarcliff Manor, New York. Illustration ca. 1886.
In the 1800s, the agrarian economy involved most Americans. In 1840, farming was the occupation of 69 percent of working Americans. Farmers weren't able to travel easily until the harvest was over. Also, the onset of winter conditions in areas that had winter conditions made travel a problem, so elections happened in the late fall.
Fun Fact #3: Ohio Constitution "No Idiots" Clause
The table used at the 1802 Ohio Constitutional Convention. Illustration by Henry Howe (1891).
Ohio's constitution prohibits "idiots" from voting. Article V, Section 6 of Ohio's constitution states "No idiot, or insane person, shall be entitled to the privileges of an elector." (Ratified: 1851)
Fun Fact #4: Texas: Vote with a Gun License or Student ID?
Texas will let you vote with a gun license, but not with a student ID.
Fun Fact #5: America's Non-elected President
President Gerald Ford campaigns at the Nassau County Veterans Coliseum in Hempstead, New York on October 31, 1976, during the final days of his failed campaign against Jimmy Carter. Photo: David Hume Kennerly/ Gerald R. Ford Presidential Library
The only President and Vice President not elected to the office was Gerald Ford. Using the 25th Amendment, President Richard Nixon appointed Ford as Vice President after Spiro Agnew resigned from the position. Nine months later, President Nixon resigned and Gerald Ford rose up in his place.
Fun Fact #6: A Cartoonist Made Political Parties' Symbols
"The Third-Term Panic", by Thomas Nast, originally published in Harper's Magazine 7 November 1874.
Cartoonist Thomas Nash is credited with creating both the Republican and Democratic symbols, the elephant and the donkey, respectively, when he lampooned the political parties in a cartoon in Harper's Weekly magazine in 1874. Soon people everywhere began using those symbols to represent the parties.
Fun Fact #7: The President was Chosen Days Prior to Inauguration in 1877
A political cartoon by Joseph Keppler (1877) depicts Roscoe Conkling as Mephistopheles (the devil) while Rutherford B. Hayes strolls off with the prize of the "Solid South," depicted as a woman. The caption quotes Goethe: "Unto that Power he doth belong Which only doeth Right while ever willing Wrong."
If you think the country endured an unreasonably long wait to find out the winner of the Bush-Gore election of 2000 (the Florida recount battle took 36 days), consider the election of 1876, which was bitterly disputed for months. Democrat Samuel J. Tilden of New York had narrowly beat Ohio Republican Rutherford B. Hayes in the popular vote, and had 184 electoral votes to Hayes's 165, with 20 electoral votes uncounted.
Hotly contested were 19 electoral votes in Florida, Louisiana, and South Carolina, with each party reporting its candidate had won the state. Meanwhile, in Oregon, one elector was declared illegally appointed and replaced. These 20 disputed electoral votes were ultimately decided by a commission of eight Republicans and seven Democrats who awarded all to the Republican candidate Hayes. He was declared the winner only three days before the scheduled inauguration on March 5, 1877, when President Grant's term ended. The infamous Compromise of 1877 saw the Democrats acquiesce to Hayes's election, in exchange for Republicans withdrawing federal troops from the South.
This spelled the end of Reconstruction, Democratic dominance in former slave states, and the rise of Jim Crow.
Fun Fact #8: New Jersey Allowed Women to Vote Longest
New Jersey State Capitol in Trenton in 1846.
The New Jersey Constitution of 1776 did not discriminate by gender when it came to voting.
[A]ll inhabitants of this Colony, of full age, who are worth fifty
pounds proclamation money, clear estate in the same, and have
resided within the county in which they claim a vote for twelve
months immediately preceding the election, shall be entitled to vote
for Representatives in Council and Assembly; and also for all other
public officers, that shall be elected by the people of the county at
large.
The gender neutral language was not an oversight. In 1797 all New Jersey counties used "he or she" to refer to voters. However, in 1807, New Jersey Women lost the right to vote in New Jersey when voting was restricted to "free, white, male citizens." This made New Jersey the last state in the country to take voting rights away from women. For more details on women's right to vote in New Jersey, see this article in the Rutgers Law Review.
Fun fact #9: First Woman to Run for President
Victoria Woodhull (September 23, 1838 – June 9, 1927), who ran for U.S. president in 1872. Photo ca. 1870 by C.D. Fredericks & Co., 587 Broadway, New York.
Victoria Woodhull, the first of more than 200 women to have run for president in America, rose from poor and eccentric origins to become one of the most colorful and vivid figures of the U.S. women's suffrage movement. In 1870, with backing from railroad tycoon Cornelius Vanderbilt, she and her sister became the first women to open a stock brokerage firm. They used their Wall Street profits to bankroll a controversial newspaper, which supported such causes as legalized prostitution and free love. Woodhull won increased respect from women's rights activists when she argued on behalf of female suffrage in front of the House Judiciary Committee in early 1871, and the following year the Equal Rights Party nominated her for president of the United States. By the time of the general election in 1872, Woodhull's enemies had gotten the better of her temporarily, and she spent Election Day in jail for publishing an article that accused the popular preacher Henry Ward Beecher of adultery. She was eventually acquitted of all charges, moved to England and married a wealthy banker.
Fun Fact #10: Women Got the Right to Vote in Utah — Twice
Emily Sophia Tanner Richards (1850-1929), key figure in the founding of the Utah Woman's Suffrage Association.
The right of women to vote was won twice in Utah. It was granted unanimously first in 1870 by the territorial legislature but revoked by Congress in 1887 as part of a national effort to stop polygamy in the territory. Mormon Emily Sophia Tanner Richards (1850-1929) and her husband were leaders of their state's Women's Suffrage Movement. In 1895 the right to vote and hold office was written into the constitution of the new state.
Winter Shanck | @wshanck
Winter Shanck, Senior Archivist at THIRTEEN, is also an avid reader and traveler and a novice writer and photographer. Follow her on Instagram @wshanck.
We Heard You! THIRTEEN Gives back Prime Time
The British Telly Dish
The Music Dish
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COVID-19 Reports on Cases and Vaccine Rollout: January 11-15
PBS NewsHour Special Reports
Black Women in Entertainment Who Performed on Their Terms


Visit exciting cities, quaint towns and captivating neighbourhoods in Washington, DC, Virginia and Maryland.
Cultural attractions, shopping, dining, quirky neighbourhoods and quaint small towns make the Capital Region of Washington DC, Virginia and Maryland a favourite holiday destination for city breaks. Soak up the urban energy of Washington and Baltimore, or opt for the quaint small-town feel of Annapolis, Maryland, or Alexandria, Virginia.
The cities of Capital Region USA are always bursting with energy, even more so during events like these.


text:
Review by Bryan Andrade Pro
The Legend of Tarzan 2016 ★★
Watched Jul 01, 2016
Bryan Andrade's review published on Letterboxd:
David Yates has a special place in my heart. He directed the final four (or three depending on how you're counting) Harry Potter films. He brought much needed weight to that franchise and brought it to a wonderful conclusion. He attempts to bring his gritty style to The Legend of Tarzan, and if this is any indication, I'm worried about Fantastic Beasts and Where to Find Them later this year.
Throughout The Legend of Tarzan's 109 minute runtime (which felt way longer) the one word that kept repeating in my head was this: lifeless. The Legend of Tarzan feels so lifeless, and it comes through in so much of its production. Set during the late 19th century, a turbulent time for Europe, the film only slightly captures some of that, using what could be an interesting blend of history and fiction to tell its story. What it ends up being is simply a predictable and shallow action film.
Featuring huge stars, The Legend of Tarzan's cast could have possible brought some life into this film. Unfortunately, most of the performances are passable, if that. Christoph Waltz plays a rather less psychotic and less charismatic version of his character from Inglorious Basterds. He does have a rosary that he uses like Indiana Jones, so that's cool, I guess. Samuel L. Jackson plays, well, Samuel L. Jackson. Alexander Skarsgard at first seemed wooden and stiff, and he loosens up quite a bit as the film progresses, but still isn't too memorable. Who does stand out here is Margot Robbie. What is unfortunate about her character is how the writers tried not to pigeonhole her as yet another damsel in distress - as is evident by her pointing it out - yet whenever it gives her a chance to take action, she ends up prisoner again, and becomes the very thing the writers were trying to avoid.
Animal CGI has improved dramatically in the past couple years. Films like Dawn of the Planet of the Apes and this year's The Jungle Book have become hallmarks for beautiful, photorealistic (more in the former than the latter) animals. The Legend of Tarzan doesn't exactly look hideous, the apes are actually done quite well, but most of the other animals - save for a couple - look borderline bad. Some moments of action where our titular protagonist is swinging through the jungle looks blatantly poorly made. What is commendable is Yates' use of close ups on characters' faces, which give the film much needed substance.
By the end of The Legend of Tarzan, I asked myself, "Wait, why are we going here again?" The truth, as it turns out, wasn't very interesting, and feels dull. There are individual pieces that work in The Legend of Tarzan, but when it all comes together, it all feels messy, and as mentioned before, just lifeless.
the legend of tarzan
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Reviewed by davidehrlich ★½
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Procedures to Get More Themes online From Store Windows 10 through steps. – Microsoft is improving Windows 10 in the direction of making most personalized and simple OS. So it has arranged Themes in Windows Store and you can install any theme from here instead of Microsoft webpages. See a guide with regard to Customize Themes on Windows 10 easily.
So here in this guide, you will learn How to Get More Themes From Store on Windows 10. If you are fond of ARC Windows 10 theme Linux (Dark and Light) grab it from here.
Step 1 – Click the Start button and let the Start menu to open. Select Settings icon from the left bar of the start menu.
Step 2 – Select Personalization on the appearing settings program.
Step 3 – Once the Personalization category loads click Themes from the left pane. Go to the right pane and select Get More Themes online from the last part.
Step 4 – You are navigated directly to the section of the Windows Store dedicated to themes. You will see numerous Windows 10 themes tiles after the store opens. So select the one you prefer and click on Get.
Step 5 – You will see that the theme is downloaded and installed in only a few moments, so click on Launch.
Step 5 – The theme will be added to the section and you can apply the same only on a single click.
In this way, you can directly Get More Themes online From Store Windows 10.
When you like to How to Get More Themes online From Store Windows 10 you must know that it contains a large number of themes by bringing from the Featured Microsoft web page. You will find Classic and charming themes from different categories. However, the themes from the different categories like Autumn, Plants & flowers, Aero, Panoramic (dual monitor), Branded and with custom sounds are placed in the store plainly. But we expect it will be arranged in a better way in the coming days.
So this is the procedure following which you can pretty simply Get More Themes online From Store Windows 10. This link has eased and shortened the way you use to download themes on your Windows 10 computer. You might have in your memory when you go to either Microsoft featured page for themes or elsewhere on the web. Now you will just select the link Get More Themes online and complete the remaining work in Windows Store. Grab a dazzling theme using this guide and enjoy.


A website maintained by the German community.
A website maintained by the Japanese community.
Brother site that holds lot of useful sites, resources and tools.
Learn more about Simutran or test yourself with our scenario collection to download.
The official Simutrans online manual, with multi-language support. Find info for gameplay and customization.
An old website with lot of Tips and Tutorials.
The Simutrans project page at SourceForge.
Download page for Simutrans nightly builds.
The official site for Simutrans translations. Makes supported languages easier to keep up to date. You can drop suggestions on the forum.
Provides information about recent changes to development versions of various parts of Simutrans.
Patches for Simutrans engine are stored here for testing.
All Simutrans related tools in one place.
A repository of maps (heightmaps) that you can use to get some real-world and non-real terrain to play on.
An online dat creator, where you can specify the parameter of the object easier. It's still under development.
A repository of pictures and files useful for creating Simutrans content.
Site to upload simutrans related stuff, specially savegames and images to be used for help requests, supports and discussions in the community forums.
The official network game server list site.
The official network game server list site for the Simutrans Extended fork.
Home of Simutrans community. The main forum language is English, but also we have subforums for other languages: Czech, German, Spanish, French, Italian, Dutch, Portuguese, Russian, Swedish and Chinese.
A dedicated forum for German speakers.
A dedicated forum for Japanese speakers.
Our official Facebook page for you to like and connect with other Simutrans players.
Our official Google plus page for you to +1 and connect with other Simutrans players.
Our IRC channel where you can chat about Simutrans.
Our IRC channel via browser, if you don't have any IRC software.
Simutrans section of Alex. Brose's site, a member of our community.
A website maintained by the Indonesian community.
A Facebook community of Indonesian players.
Blog where Zeno post his last creations and tutorials.
A Hispanic Simutrans website, dedicated for all Hispanic players.
Website with Simutrans developer tools created by VS.
Japanese site with some tools and addons made by Wa.
Website with stuff made by Zeno, a community member.
Review made by Freegamer in 2009, using Simutrans 101.0 with pak128 and pak96.comic.
Portuguese review about Simutrans 110.0.1 with pak64. Also present a user rating system.
Website have an user rating system about Simutrans, also have a download link to it, but for an outdated version.
Simutrans section in Open Source Nevada.
Link for outdated version of Simutrans, but with user rating system.


"Development of low cost portable machine for the evaluation of quality of tea : brain storming meeting on 2nd September, 2017 at the Centre"
Mr. Sumanta Kundu, SRF of the Centre presented poster on the topic 'Oscillating Percolation' in the conference "Fundamental Problems in Statistical Physics XIV" at Bruneck, Italy.
Sutapa Dutta, SRF of the Centre presented poster in the conference "Conformational Ensembles from Experimental Data and Computer Simulations" in Berlin, Germany on the topic 'Temporal correlations among functionally important distant residues of ubiquitin'.
The S.N. Bose Centre has taken up many activities / events as per the "Swachhta Action Plan" during 15th September to 2nd October, 2017 viz.- Mass Pledge of all employees of the Centre, Swachhta Awareness Programmes through a drama of short duration, Poster presentation and circulation on the theme "Zero Plastic Green Campus", Mass Cleaning of surroundings including removal of weeds /shrubs /herbs /unwanted plants etc., Cleaning of rooms/ halls/ toilets/window panes, Removal of cobwebs, Broken glasses etc. Some glimpses of the event are presented herewith.
Director and staff of the Centre have taken oath on "Swachhta Hi Seva" at 3.00 PM on 25th September, 2017.


text:
Biography Chioma Nnamaka
Chioma Nnamaka
by Vineet 03 Dec,2019
Weight 140 lb (64 kg)
Famous Name
Birth Name Chioma Nnamaka
Birth Place Uppsala, Sweden
Famous Name Chioma Nnamaka
Birth Date June 15, 1985
Father Jonathan Nnamaka
Father Nationality Nigerian
Mother Ann-Katrin
Mother Nationality Swedish
Net Worth $850 thousand
Salary $95,000
Nationality Swedish
Affair with Single
Chioma Nnamaka is a Swedish professional female basketball player and a member of Sweden women's national basketball team who has played for several WNBA teams like Georgia Tech and Atlanta Dream. Also named the most valuable player of the Swedish championship in 2003, she played college basketball for Georgia Institute of Technology Women's Basketball Team.
Born on June 15, 1985, in Uppsala, Sweden, Chioma completed high school from Fryshusets Kunskaps Centrum and after visiting in the United States, she got admission to Georgia Tech. She was selected 21st overall in the 2008 WNBA Draft by the San Antonio Silver Stars and became the highest draft pick ever chosen from Georgia Tech.
Net worth and Salary
The 34-year-old WNBA star has an estimated net worth of around $850 thousand in 2019. It was the 2008 WNBA draft where she was picked up by San Antonio Silver Stars and she gained $45,000 as a signing amount.
She is also the basketball player for Sweden National Team and from her national leagues, she has earned probably $350,000.
Chioma Nnamaka SOURCE: Linkedin @chiomannamaka
While playing with Georgia Tech, she earned $95,000 as an annual salary and she has also got $35,000 from her crossover contracts.
Relationship and Family
6 ft tall Swedish national player is unmarried and reportedly single currently. She is a hard-working player and has gained a good fortune and fame through WNBA tournaments. She is focused on her career and might think about her personal life after her retirement.
Chioma Nnamaka is a daughter of Jonathan Nnamaka who is Nigerian and her mother's name is Ann-Katrin who is a Swedish. Her parents met when her father moved to Uppsala to attend university. The couple married sometime later and were blesses with four children.
She belongs from an athlete family where her older brother, Oluoma, is currently playing professionally in Italy following a career at Marquette University and her two older sisters, Azuka and Ifeanyi, both play professionally in Sweden's highest league.
Nnamaka has done major in International Affairs at Georgia Tech, Nnamaka has always wanted to pursue a career in law enforcement (as a police detective) once she finishes her basketball career.
Career and Achievements
Chioma was picked 21st overall by San Antonio Silver Stars in 2008 WNBa Draft. She was traded to the expansion team Atlanta Dream the same day, where she completed her rookie season. On January 14, 2009, Nnamaka was waived from the roster.
Earlier, she played in the Swedish Championship where she was the Most Valuable Player in 2003. She was also the Co-Captain of the Georgia Institute of Technology Women's Basketball Team from 2006- 2008.
In 2004 she was mentioned as All Atlantic Coast Conference Freshman and in the same year, she became Atlantic Coast Conference Rookie of the week.
WNBA Women's National Basketball Association (WNBA) 2008 WNBA Draft Chioma Nnamaka


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Enns Titanic story in last the April 18 Daily News, I would like to share my story with your readers. I grew up in English countryside just outside the village of Lowdham in Nottinghamshire. A few houses down our road celine outlet italy airlines lived a man called Harold Cottam. He was a bit of a recluse; lived in a three bedroom Victorian house where he only used two rooms beside the chickens that lived in the front bedroom. The rest of the house was used for the storage of his many "world treasures" boxes and boxes of exquisite Japanese tea services, vases, carved boxes and swords amongst other things. I first met Harold when I was about nine or 10. I went to visit him with my neighbour, Chris Payne, who knew celine luggage tricolor him. It was then that I found out Harold had been involved in the rescue of survivors of the Titanic. He had been the celine crossbody handbag radio operator on RMS Carpathia, the ship that received the Titanic's distress signal and buy celine bags on celine outlet online subsequently went to its rescue. As a kid, I found Harold extremely interesting and would go to visit him fairly regularly. I'd do yard work and he would pay me in ice cream. There we would sit in his front room or in his garden, me with a bowl of raspberry ripple and he would enthral me with stories of his life. He had sailed the world more than once. He had been on the RMS Carpathia in Istanbul during the Turko Italian War and had been on one of the first ships through the Panama Canal. In the First World War, he had been stationed in Scotland working at a secret relay station picking up German radio transmissions. But it was with his stories of the Titanic (and of his late wife Else) that he always had sadness in his voice. I don't know how much your readers know about early radio, but in 1912 when the Titanic sank, radio (or wireless as it was then known) was a very new technology. There were no microphones, this was headphones and a Morse code transmitter. On the night of April 15, 1912, Harold was getting ready to turn in for the night and was waiting for another ship to reply to a message. While he waited he called up the Cape Cod transmission station and noticed there were several messages waiting for the Titanic and decided to be helpful and pass the messages on to Jack Philips, the wireless operator on the Titanic. Harold actually missed the Titanic's first distress call as he had removed his headphones to take off his shoes and hang up his coat. When he got his headphones back on he called up the Titanic to check it had received his message only to receive a CQD signal (the forerunner to the modern SOS signal): "Come at once, we're sinking!" After receiving confirmation from the Titanic, he went and woke up his captain, who then set course at full steam for the Titanic. The Carpathia was a steam side paddlewheeler with a top speed of only 17 knots or 20 mph, so to keep this speed up, the captain ordered all of the ships' heating and hot water be turned off. It took the Carpathia about four hours to steam the 60 nautical miles to the last known position of the Titanic where it picked up just over 700 survivors. My friend Harold was born in Southwell, Nottinghamshire, and died in Lowdham, Nottinghamshire, about 15 miles apart. In between, he had been the youngest graduate from the British School of Telegraphy at only 17, had seen the world (several times) and had been a major player in the disaster of the century all by the age of 21. Harold retired from the sea at the age of 32 to become a where to buy celine bags online traveling salesman for the Mini Max fire extinguisher company.
He was married and had four children. Are there any other Titanic stories out there RICK PRESCOTT Knutsford. .
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After the 2008 Olympics in Beijing, the next global event to take place in China has begun.
There's a good reason why steel is regarded as a particular challenge for designers.


text:
package com.google.android.exoplayer2;

import androidx.annotation.Nullable;
import com.google.android.exoplayer2.util.Assertions;

/**
 * @deprecated Use {@link Player#setPlaybackSpeed(float)} and {@link
 *     Player.AudioComponent#setSkipSilenceEnabled(boolean)} instead.
 */
@SuppressWarnings("deprecation")
@Deprecated
public final class PlaybackParameters {

  /** The default playback parameters: real-time playback with no silence skipping. */
  public static final PlaybackParameters DEFAULT = new PlaybackParameters(/* speed= */ 1f);

  /** The factor by which playback will be sped up. */
  public final float speed;

  private final int scaledUsPerMs;

  /**
   * Creates new playback parameters that set the playback speed.
   *
   * @param speed The factor by which playback will be sped up. Must be greater than zero.
   */
  public PlaybackParameters(float speed) {
    Assertions.checkArgument(speed > 0);
    this.speed = speed;
    scaledUsPerMs = Math.round(speed * 1000f);
  }

  /**
   * Returns the media time in microseconds that will elapse in {@code timeMs} milliseconds of
   * wallclock time.
   *
   * @param timeMs The time to scale, in milliseconds.
   * @return The scaled time, in microseconds.
   */
  public long getMediaTimeUsForPlayoutTimeMs(long timeMs) {
    return timeMs * scaledUsPerMs;
  }

  @Override
  public boolean equals(@Nullable Object obj) {
    if (this == obj) {
      return true;
    }
    if (obj == null || getClass() != obj.getClass()) {
      return false;
    }
    PlaybackParameters other = (PlaybackParameters) obj;
    return this.speed == other.speed;
  }

  @Override
  public int hashCode() {
    return Float.floatToRawIntBits(speed);
  }
}

redpajama_set_name: RedPajamaGithub


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text:
Q: How to setup ssl (https) for your site on Ubuntu Linux - Two way SSL I have a website, the main requirement is to make that website secure by using https
When the client access from a different machine it has to work only if the certificate had uploaded in the browser settings.
If not it should deny the access to that website. Can anyone help me achieve this.
I am using Ubuntu 14.04
Let me know if you people need any more details

A: It tunrs out that the official documentation of Apache (see at this link) is really well done on this subject.
In short, you should end-up with something like this :
LoadModule ssl_module modules/mod_ssl.so

Listen 443
<VirtualHost *:443>
   DocumentRoot /var/www/yoursite/
   <Directory /var/www/yoursite/>
     AllowOverride All
     order allow,deny
     allow from all
   </Directory>

   ServerName www.example.com
   SSLEngine on
   SSLCertificateFile /path/to/www.example.com.cert
   SSLCertificateKeyFile /path/to/www.example.com.key

   SSLVerifyClient require
   SSLVerifyDepth 1
   SSLCACertificateFile /path/to/www.example.com.ca.crt
</VirtualHost>

Some details on the above

*

*LoadModule ... : to load the appropriate Apache module, containing the SSL implementation

*Listen 443 : Apache daemon will listen on the standard HTTPS port, 443

*DocumentRoot : where the files of your site reside

* ...  : this is the definition of the options for your web site's directory (there are a lot more, the mentioned ones here are the basic one to allow access from any IP on the Internet).

*ServerName : to serve only URL containing this name

*SSLEngine on : activate the SSL features on this website.

*SSLCertificateFile : path the X.509 certificate of the private key created for this server.

*SSLCertificateKeyFile : path to the private key created for this server.

*SSLVerifyClient require : enforce the server to ask the client for a valid certificate

*SSLVerifyDepth 1 : must be directly signed by the CA mentioned in the next instruction

*SSLCACertificateFile : path the X.509 certificate of the CA that signs the certificates used by the clients.

The certificates
You will have to get valid certificates, one for your server and many other for the clients.
For the server
Install OpenSSL tool, if not yet done : sudo apt-get install openssl.
With this tool, you can create the private key of the server :
openssl genrsa -des3 -out server.pass.key 2048

The above command creates a private key with a password. To be loaded automatically by your server, you have to remove the password :
openssl rsa -in server.pass.key -out server.key

You have now a valid server private key in a file, this is the file pointed by the SSLCertificateKeyFile Apache directive.
From this private key, you will create a Certificate Signed Request (CSR) :
openssl req -nodes -new -key server.key -out server.csr

You are going to be prompted to enter a set of elements (country, organization, ...). The most important one will be the Common Name (CN), it must match the hostname of your webserver, the one used in the URL. So in my example it is www.example.com.
Then, you have to submit this CSR file to your certificate provider. Any public CA is good. After they've approved your requested, they will send you the famous X.509 certificate file for your server. This file will be pointed by the SSLCertificateFile Apache's directive.
For the client
You will have to provide valid certificate to the client too.
Based on the client type (Linux, Windows, MAC, ...) the process may differ.
Sometimes, for the client certificates, all the operation can be done directly from the web browser by visiting the page of the CA registration. If done directly from the web browser, than you are sure that the certificate is automatically registered into the certificate DB of the web browser.
If done by an external means (like openssl on Linux), you will have to import the private key and certificate file into the certificate store of your web browser.


text:
Civic Affairs
County leaders mull merging PPB, MultCo Sheriff's Office
by: Lisa Balick, KOIN 6 News Staff
Posted: Oct 20, 2020 / 08:45 PM PDT
Updated: Oct 21, 2020 / 05:21 PM PDT
The city of Portland extends into 3 different counties
PORTLAND, Ore. (KOIN) — Protesters have called for a defunding of the Portland police but some officials are now discussing eliminating the bureau as we know it.
Multnomah County officials are considering a plan that would merge the Portland Police Bureau with the Multnomah County Sheriff's Office.
County Commissioner Sharon Meieran talked about the idea at the end of a local public safety coordinating council last week.
"I think we need to reevaluate the relationship between the sheriff's office and PPB and whether it is actually time to potentially merge them in a meaningful way," Meieran said. "I know there are challenges about this, I know it has been discussed in the past but there are tremendous benefits as well. I think we at least need this to be part of our conversations as we are re-envisioning justice."
The meeting took place hours after protesters tore down two statues and broke windows at the Oregon Historical Society.
Meieran, who is also an emergency room physician, said the idea of combining police officers and county deputies is especially relevant at a time when re-envisioning community safety is center stage. Meieran said the merger would free up resources to provide services to help people before they get into criminal trouble and to take a different approach in responding to people experiencing mental health crises.
Many county employees are trained to handle issues involving mental health and substance abuse. Meieran said they could help with training and crisis response. She believes the idea of combining police and deputies — something that has been done in several other cities across the country — needs to be a community conversation.
In a statement, Mayor Ted Wheeler said the proposal of merging the PPB with the MCSO would take considerable time and effort but should be considered. A likely problematic issue to arise moving forward is the fact that parts of Portland extend into Washington and Clackamas counties.


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text:
Obama Demands Israel Apologize To Islamist Erdogan For Stopping Terror Flotilla…Or Else!
Posted by Matthew Knee Thursday, August 18, 2011 at 08:15am 9 Comments
Israel Today reports that the Obama Administration has demanded that Israel apologize to Turkey for last Summer's raid on the Mavi Marmara, a Turkish-flagged ship leading a "Freedom Flotilla" of "peace activists," which attempted to break the blockade on the Terrortory of Hamastan (a.k.a. Gaza).
This motley crew of Hamasophiles included not only the IHH, a group that apparently has ties both to Turkey's ruling AKP political party and Al-Qaeda, but was also part of a movement aided by Obama allies such as Code Pink and his friendly neighborhood (retired) terrorists, Bill Ayers and Bernadine Dohrn.
Islamist Turkish Prime Minister Recep Tayyip Erdogan, a former mayor of Constantinople Istanbul oft heard raging against conquest and occupation, called the operation an act of piracy. While he as Prime Minister arguably committed an act of war by encouraging a ship flying his nation's flag to violate territory controlled by another, Erdogan's self-righteous chutzpah was undiminished, and, like a man who kills his parents and pleads for mercy because he is an orphan, Erdogan demanded an apology and compensation from Israel for the "victims'" families.
Now, Obama is demanding that Israel apologize to Turkey, because our interests are being harmed by deteriorating relations between Israel and Turkey. They are, but because Turkey has changed, not because Israel has. The rise of Erdogan's Islamist APK party, aided by Obama-and-EU-backed "reforms" that weakened the military's role in safeguarding their country's secular character, has led Turkey steadily down an anti-Israel path from the time he was first elected in 2002. However, in classic Obama fashion, the president fails to recognize the culpability of the Islamist aggressors. Rather, he blames those who dare assert their rights against them, believing that the path to peace is through obeisance and surrender.
To recap, here is what Obama claims Israel must apologize for:
On May 30, 2010,the Mavi Marmara was stopped by the Israeli navy attempting to violate the Gaza blockade. It contained no actual humanitarian aid, and was sent as part of a tactic to secure unrestricted supply lines to Hamastan in the future. (Alas, the revolution in Egypt very well might have that effect anyway)
Ordinarily, Israel escorts such ships into an Israeli port, checks for contraband, offloads aid, and delivers it to Gaza by truck. When Israel's navy stopped and boarded the ship for inspection, as they had every right to according to international law, they were ambushed by armed terrorist supporters. The soldiers, under orders not to use lethal force unless their lives were threatened, were armed only with non-lethal weapons and sidearms. An IDF patrol boat caught the brutal attack on video, and the ship's own security cameras document the preparation of the ambush.
Some peaceful protesting by the Freedom Flotilla.
Some of these individuals, armed with pipes, knives, axes, chains, slingshots, and pistols taken from some of the first soldiers to board, came in search of martyrdom. For instance, this man, disappointed at his failure to die during two previous attempts, told a journalist he hopes to finally achieve martyrdom this time out. Others, like this charming individual pictured below, were also far from peaceful.
Nothing says "peaceful protest" like a big, stabby, knife.
Ultimately, the boarding party was forced to open fire, with the last boarder, known only as St-Sgt. S, killing six and stabilizing the situation after the many of his comrades had been wounded. Ultimately, nine from the flotilla were killed.
Israel later released the ship back to Turkey, and Sefic Dinc, a particularly ethical Turkish journalist who was aboard the Mavi Marmara to cover its exploits, wrote a book largely confirming that Israel's account of the incident was true.
BarbaraS | August 18, 2011 at 9:24 am
I hope Netanyahou tells him to take a hike. If the situation wasn't so tragic it would be a comedy. Skippy, as always, is on the wrong side of the opinion of the American people. Every thing he does and says shows how he was never taught basic American traditions. And, after some of the things he has said, one wonders if he was educated at all.
DINORightMarie | August 18, 2011 at 9:51 am
The best thing to do, IMHO, is ignore this ridiculous ultimatum/threat. There is no power in Washington. No leadership. No coherent foreign policy. The threat is empty.
This embarrassing, weak Administration has already publicly chastised, denounced, and criticized Israel – just short of publicly revoking US support – which exposes their weakness even more. They would NEVER renounce support of Israel coming into a presidential election.
Remember Obama and Hillary reassuring the public of their unequivocal, unwavering support for Israel in 2008? Yeah, they know they are weak. And, frankly, they know they can't erode the Jewish-American vote any more than they have already. Paper tigers.
At most, if asked, Bibi would do well to re-state the law, the Mavi Maramara's breach of the blockade and international law; IMHO, of course.
Again, to address this foolishness would give it merit, credibility. Bibi is too smart, too good a leader to bite.
Don't take the bait.
Joy in reply to DINORightMarie. | August 18, 2011 at 10:12 am
Don't worry, Bibi didn't take the bait 🙂
http://www.jpost.com/DiplomacyAndPolitics/Article.aspx?ID=234150&R=R1
boudicca | August 18, 2011 at 10:13 am
In a Warning to America in Nashville on May 12 Geert Wilders of The Netherlands said: If Israel falls, we all fall. We are all Israel. Israel is fighting our fight. Yet, President Obama acts to undermine and weaken Israel at every turn. why?
Here's an except of Wilders' speech.
"Rivers of tears are flowing from the Middle East, where there is only one safe haven for Christians. You know where that is. The only place in the Middle East where Christians are safe is Israel.
That is why Israel deserves our support. Israel is a safe haven for everyone, whatever their belief and opinions. Israel is a beacon of light in a region of total darkness. Israel is fighting our fight.
The jihad against Israel is a jihad against all of us. If Israel falls, we, too, will feel the consequences. If Jerusalem falls, Athens, Rome, Amsterdam and Nashville will fall. Therefore, we all are Israel. We should always support Israel!"
http://www.geertwilders.nl/index.php?option=com_content&task=view&id=1750&Itemid=1
Vascaino | August 18, 2011 at 11:10 am
What can one expect when the NYT's reporter writes that Israel "Claims" that its soldiers were attacked.
http://www.camera.org/index.asp?x_context=2&x_outlet=35&x_article=2100
"New York Times Presents Attack on Soldiers by Mavi Marmara Activists as Israeli Claim"
Who is the Whitehouse to believe? The Jews?
Crawford | August 18, 2011 at 11:31 am
"Islamist Turkish Prime Minister Recep Tayyip Erdogan, oft heard raging against conquest and occupation from his lofty perch in Constantinople Istanbul…"
The Turkish government is based in Ankara, not Istanbul.
Unless you're talking about a "lofty perch" other than his government role…
Matthew Knee | August 18, 2011 at 12:50 pm
Erdogan is an Istanbul native and former Mayor of Istanbul.
DougV in reply to Matthew Knee. | August 18, 2011 at 5:37 pm
Plus, "It's Istanbul not Constantinople" always runs through my head when ever Turkey is discussed.
LukeHandCool | August 18, 2011 at 3:07 pm
Israel: "Excuuuuse us for living!!"