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home/ cholesterol drug doesn't cut heart attack risk article
Cholesterol Drug Zetia Doesn't Cut Heart Attack Risk: Study
By Ed Edelson
MONDAY, Jan. 14 (HealthDay News)-- The long-awaited results of a trial of Zetia, a cholesterol-lowering drug prescribed to about a million Americans, shows the drug confers no medical benefit to users.
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In fact, the pace at which artery-clogging plaques formed within vessels almost doubled in patients taking Zetia (ezetimibe) along with another cholesterol-lowering drug, Zocor (simvastatin), compared to those taking Zocor alone, the study found.
The two medications -- ezetimibe plus simvastatin -- are also marketed in one prescription pill, called Vytorin. About 60 percent of U.S. patients who are taking Zetia now receive the drug as part of Vytorin.
But the new two-year trial of 720 patients sheds doubt on whether it makes any sense for people battling cholesterol to take Vytorin versus Zocor alone, experts said. The study was funded by the two companies that make Zetia, Merck and Schering-Plough.
"This wraps it up," said Dr. Steven E. Nissen, chairman of cardiology at the Cleveland Clinic. "That's all there is. There just isn't any evidence that adding ezetimibe to simvastatin produces any advantage."
No one is disputing that Zetia can lower levels of LDL "bad" cholesterol by 15 percent to 20 percent -- that had been shown in previous trials. However, whether that reduction led to any greater lowering of heart attack or stroke risk had remained unclear.
The new ENHANCE trial -- which involved patients with a genetic condition that causes abnormally high levels of blood cholesterol -- found no such added benefit. According to a statement released by the two drug companies Monday, researchers found no statistically significant difference in heart attacks or stroke among trial participants who took Zetia plus Zocor, a widely used cholesterol-lower drug, versus those who got Zocor alone.
The study also noted that the speed at which arteries thickened with plaque almost doubled among those on the two-drug regimen compared to those taking Zocor alone.
Safety profiles were similar for Zetia/Zocor versus Zocor alone, the team added.
"These results are very important considerations on how we treat patients with elevated cholesterol and will very likely impact the way we choose drugs to lower cholesterol and eliminate plaque," said Dr. Howard Weintraub, clinical director of the Center for the Prevention of Cardio-Vascular Disease at New York University Medical Center, New York City, and clinical associate professor at the NYU School of Medicine.
"ENHANCE found that plaque got slightly worse when the drug combination was used," Weintraub noted in a statement. "But, the real take-home message here is that getting LDL down is important, and that's not something that should be lost as a consequence of this study."
The ENHANCE study was completed in April 2006, but the results were only released Monday by Merck and Schering-Plough after continual prodding by medical professionals. According to The New York Times, the companies had initially planned to release the findings by March 2007, but then missed several self-imposed deadlines, blaming the delay on the complexities of necessary data analysis.
Now that the results have arrived, Zetia and Vytorin should be viewed as "drugs of last resort," for patients not helped by standard statin therapy, Nissen said. Only if you can't tolerate full doses of simvastatin should you take ezetimibe, he said.
"This is one of the most widely advertised and widely used drugs out there, so it's obviously good to get these study results," Nissen added.
Another group questioned why patients should be prescribed more expensive cholesterol-lowering drugs, such as Vytorin, versus cheaper, generic statins such as Zocor.
"We already know that millions of people who take these brand drugs probably don't need to; they could be taking a less expensive generic instead. This study lends support to that cost-saving strategy for the health system and for consumers," said Steven Findlay, managing editor of Consumer Reports Best Buy Drugs, a public information and education project of Consumers Union, publisher of Consumer Reports.
"If there is no apparent clinical benefit, why take a drug that cost three or four times more?" Findlay said in a statement. "Most people do not need that magnitude of cholesterol reduction anyway."
Sales of Zetia and Vytorin totaled $3.7 billion in the nine months ending Sept. 30, up 33 percent from a year ago. Analysts estimate that about 70 percent of Schering-Plough's earnings depend on the drugs, the Times noted.
SOURCES: Steven Nissen, M.D., chairman, department of cardiology, Cleveland Clinic; Howard Weintraub, M.D., clinical director, Center for the Prevention of Cardio-Vascular Disease, New York University Medical Center, and clinical associate professor, NYU School of Medicine, New York City; Merck/Schering-Plough Pharmaceuticals, news release, Jan. 14, 2008; Consumers Union, news release, Jan. 14, 2008; The New York Times
Copyright © 2008 ScoutNews, LLC. All rights reserved.
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The development of a just society requires universal participation.
Why? Why is this the case? If you'd like, respond with your thoughts below.
Surely, there are many of reasons. Three come to my mind at the moment. They are related to unity, capacity building, and knowledge.
The purpose of justice is to bring about unity within human society. This is a basic reason why all who are a part of this society need to be involved in its development; otherwise how could one claim unity, when some are spectators and some are protagonists? More significant than the actual actions of various people (because of course, contribution to society's development is a spectrum; some more active, some less) it is the mindset of "us" and "them" – of otherness – that hinders unity.
One of the manifestations of justice is that the capacity of each created thing is revealed to its fullest. Obviously, this, too, is a spectrum. But, to use a tree as a simple example, it is just that a tree be allowed to bear its fruit. Human beings have infinite talents and capacities, especially when each individual is viewed as part of a collective humanity. In order to fully express the collective capacity of humankind, opportunities must be created for each individual to contribute to humanity's well-being and development, according to his/her talents. Otherwise, if only some develop capacities while others don't, the collective capacity of humankind will not fully be actualized, which is not just.
Finally, justice is the process of investigating truth through one's own eyes, and not through blind imitation of what has been already stated. A human being who undertakes an exploration of reality with justice will necessarily have a unique perspective, since it is through his/her own eyes – some may say that it is subjective. We know that reality is multi-faceted. As an example, imagine that it's a sphere. Each individual will view from a particular angle, perhaps seeing a disc. It is only as more and more subjective perspectives are harmonized together will reality be objectively known and understood. Justice demands universal participation, because it is only through a diverse range of perspectives that our multi-faceted reality can be known, and justice is the process by which we understand truth.


We recently completed the installation of the Rosslinear wireless battery powered electric strike by Lock Focus for a customer who required communal access to a parking lot, but was frightened by the monumental cost of installing a hardwired access control point.
This particular installation was difficult because the fence/gate builders had constructed it using heavy gauge wrought iron (1/4" thick) and it took substantial time to cut out the material.
When you consider the average cost of other stand-alone battery powered access control locks (~$800) prior to installation, this new product allows you to maintain a conventional entrance set with key override but still enjoy the convenience of superior access control. With up to 200 user codes (depending on code length), the ability to temporarily lock out all users (except administrator), a passage mode, adjustable time delay (length of time before unit re-locks) and other optional extras. At less than $460.00 this is a suitably competitively priced alternative.
We are the exclusive dealer of this product in the North American market.


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Q: Active Directory: How to determine whether account is service account? Question: Is it possible to determine whether an account is a service account in Active Directory using C# LDAP? If yes, how?
Context: I have a program that is retrieving all objects of schema class type USER, GROUP, COMPUTER, FOREIGN SECURITY PRINCIPAL, and CONTACT. Currently, a service account is identified by string parsing the canonical name for 'service account'. I do not like this solution because string parsing is dependent on a folder location in the hierarchy that literally says 'service account'. It seems possible that a service account could be created and then placed in a folder path that does not include the string 'service account'. Unfortunately, I cannot test this because I am not an AD admin.
I have browsed around online without any luck so I am not sure if it is even possible.
Update:
Per Microsoft, it appears that the service account is contained in objectClass msDS-ManagedServiceAccount. However, when I set the DirectoryEntry filter to msDS-ManagedServiceAccount, no results are returned.
directoryEntry = new DirectoryEntry(strActiveDirectoryHost, null, null, AuthenticationTypes.Secure);
string strDsFilter = "(objectClass=msDS-ManagedServiceAccount)";

DirectorySearcher directorySearcher = new DirectorySearcher(directoryEntry)
{
    Filter = strDsFilter,
    SearchScope = SearchScope.Subtree,
    PageSize = intActiveDirectoryPageSize,
};

return searchResultCollection = directorySearcher.FindAll();

A: I have testing your code, and it does in fact return results in my environment. A few things to note:

*

*Be sure that strActiveDirectoryHost is formatted correctly. The format should be LDAP://DC=contoso,DC=com

*Check that you are searching from the root (or high enough to find the accounts you are looking for). MSAs are under the Managed Service Accounts container under the domain NC (i.e. LDAP://CN=Managed Service Accounts,DC=contoso,DC=com)

*In my tests, I call new DirectoryEntry() with only the path. Not sure if passing AuthenticationTypes.Secure is causing an issue for you

*The objectClass you have is correct.

A: So I am working on this to get the MSA as well as create them. I am able to get the MSA using the System.DirectoryServices.AccountManagement namespace, still working on creating it (unsure if this is really possible)
But for finding the accounts which are MSAs you can use the below code
PrincipalContext oPrincipalContext = new PrincipalContext(ContextType.Domain, sDomain, sDefaultOU, ContextOptions.SimpleBind, sServiceUser, sServicePassword);
GroupPrincipal currentGroup = GroupPrincipal.FindByIdentity(oPrincipalContext, "YourGroupName");
        foreach (Principal a_principal in currentGroup.GetMembers())
        {
            if (a_principal.StructuralObjectClass == "msDS-ManagedServiceAccount")
            {
                Console.Write(a_principal.SamAccountName); //To get the name
                ComputerPrincipal oComputerPrincipal = ComputerPrincipal.FindByIdentity(oPrincipalContext, a_principal.Name); //creating a computerprincipal to get more details about the MSA

            }
        }

You can use the above logic and create a Principal for the user account and get the structural object class for that account to find out if it is MSA.
Something like this:
 UserPrincipal oUserPrincipal = UserPrincipal.FindByIdentity(oPrincipalContext, sUserName);
      if (oUserPrincipal.StructuralObjectClass == "msDS-ManagedServiceAccount")
                {
                    Console.Write(oUserPrincipal.SamAccountName); //To get the samaccountname
                }

redpajama_set_name: RedPajamaStackExchange


The ladies pulled the dress out for me and I tried it on. I loved it. It was flattering and simple.
Looking at these pictures though, I am GLAD I didn't choose this dress- the back is not so hot on me.
The next dress I didn't really want to try on, but they asked me to since it was similar to the 1831. I agreed, and am lucky that I did. It ended up being my dress! I never felt an "angels singing" moment, but I didn't really expect to. I loved the dress, it was comfortable, everything I was looking for and I didn't want to try on dresses anymore.
John don't look! I will fight you!
I got the Casablanca 1908.
The front- sparklies and a wrap top with a dropped waist. The dress is ivory with blush pink accents. The torso area is pleated with the ivory and pink (which is very muted). This dress was a size too small for me, so its a little rough looking.
The back is pretty awesome- very Cinderella-y. I think it will look sweet with e french/under bustle.
Oh- yeah- we are DEFINITELY crossing the straps in the back. Suh-weet.
I knew I was on a short timeline for the whole dress ordering thing. I had less than 5 months (which I think is about the amount of time it takes on average to get a dress ordered). Yikes. Casablanca makes the dresses as the orders come in, so that adds a little extra time to the order, not leaving very much time at all for shipping or alterations.
Since the dresses are made to order, I had the option of paying something like $30 more and having them make the dress to my exact measurements. We did this, and if all goes well, I won't NEED alterations.
Right now, the dress is scheduled to ship the week before Christmas. Yes, a couple of weeks before the wedding. I have a plane ticket to go to NY the Saturday after Christmas to try it on, get any necessary alterations and a bustle. Hopefully it doesn't get lost in the mail!


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Alba Iulia (stariji hrvatski naziv: Erdeljski Biograd, stari rumunjski i slavenski naziv: Bălgrad, njemački:Karlsburg, Carlsburg ili Weißenburg, mađarski:Gyulafehérvár, u starijim izvorima Károlyfehérvár, Erdélyifehérvár, Fehérvár i Fejérvár) je grad u središnjoj Rumunjskoj, glavni grad županije Alba.

Zemljopis
Grad se nalazi se u južnom djelu povijesne pokrajine Transilvanije. Grad je smješten u dolini rijeke Moriša, na mjestu gdje iz ove doline lak prelazak ka susjednim dolinama rijeka Samoša na sjeveru i Olta na jugu. Zbog toga je grad važno prometno središte ovog djela Rumunjske.

Stanovništvo
Po popisu stanovništva iz 2002. godine grad ima 66.406 stanovnika, dok je prosječna gustoća naseljenosti 698 stan/km²

 Rumunji: (94,45 %)
 Mađari: (2,76 %)
 Romi: (2,22%)
 Nijemci: (0,32 %)

Zanimljivosti
U katedrali sv. Mihaela pokopano je tijelo vojskovođe Janka Hunyadija.

Gradovi prijatelji
  San Benedetto del Tronto, Italija
  Stolni Biograd, Mađarska
  Biograd na Moru, Hrvatska
  Arnsberg, Njemačka
  Nazareth Illit, Izrael
  Aeghio, Grčka
  Sliven, Bugarska
  Duzce, Turska
  Varese, Italija

Izvori

Vanjske poveznice
Službena stranica grada
Erdeljski Biograd, katedrala, fotografija , Pticica.com

Ostali projekti

Gradovi u Rumunjskoj

redpajama_set_name: RedPajamaWikipedia


It is a very smart design! This design combines the drawing and television together, so there is no necessity to void a space for television. It uses space wisely.
People can lie in beds and watch televisions; therefore, they won't feel painful from the necks if they watch television for a long time. However, if I'm a customer, I'm afraid the television will fall down, or if I forget to put the television back, I'll hit it when I get up. I'm also wandering whether I can connect an audio with it.


Our selection Sports games is packed with great classics and the best new online games. Bubblebox.com is the perfect place to find free online sport games! If you consider dog racing a sport make sure you don't miss Gone to the Dogs 2, if you're into Base Jumping try Elite Base Jump and if you like something that really get the adrenaline pumping try Ragdoll Volleyball!


text:
Ascension Healthcare plc: Business Update
November 29, 2021, 2:00 a.m. ·5 min read
Ascension Healthcare plc
Business Update
~ Progress across Haemophilia clinical programmes and further expansion of Consumer Healthcare business~
LONDON, November 29, 2021 – Ascension Healthcare plc ("Ascension" or the "Company"), a clinical-stage biopharmaceutical company focused on developing and commercialising innovative therapies for haemophilia and osteoarthritis, today provides an update on its haemophilia clinical programmes and consumer healthcare business.
Ascension's 'SelectAte' Phase 2 clinical development programme is aimed at evaluating the efficacy and safety of the Company's proprietary pegylated liposome (PEGLip) technology in providing prophylactic Factor VIII (FVIII) replacement therapy to inhibitor and non-inhibitor patients suffering from severe Haemophilia A. SelectAte involves the intravenous co-administration of PEGLip with a commercially available recombinant FVIII. The inhibitor arm of the study is almost complete with 9 patients out of 10 processed and the non-inhibitor arm comprising 10 patients has completed. Positive results have been observed to date across both arms indicating the potential for a safe FVIII replacement treatment for inhibitor patients and an extension of dosing interval when compared to existing FVIII replacement therapies.
Ascension's 'XLR8' (formerly 'ChapAte') Phase 2 clinical programme is aimed at evaluating the efficacy and safety of the Company's PEGLip technology in prophylactically treating non-inhibitor patients via a separate administration of PEGLip, following an initial loading dose of FVIII. Positive results were obtained from this study, also indicating the potential for an extended dosing interval, without compromising haemostatic cover, in patients currently receiving prophylactic FVIII standard of care.
Final study reports will be available for both SelectAte and XLR8 in Q1 2022.
Dr Gavin Ling, Chief Medical Officer of Ascension commented: "It is very encouraging to see initial positive data from both the SelectAte and XLR8 trials, demonstrating the potential of our PEGLip technology in providing prophylactic FVIII replacement therapy to patients suffering from severe Haemophilia A. We look forward to announcing the full data sets for both trials early next year and are excited about moving into Phase 3 with a dosing interval that extends beyond any currently licensed FVIII treatment."
Biresh Roy, Chief Executive Officer of Ascension added: "Ascension is excited to provide this update regarding the positive clinical progress of its lead Haemophilia A programmes, which offer the potential for safe, effective FVIII replacement therapies, particularly for inhibitor patients. The results are further evidence of our unique PEGylated liposomal technology in this area of unmet medical need and provide a firm foundation as the company seeks financing to progress its studies into Phase 3 clinical development in 2022."
Despite the challenges of COVID-19, Ascension's Consumer Healthcare business performed strongly during the period. Earlier in the year, the Company successfully rebranded its core FlexiSEQ product, containing Ascension's patented Sequessome® technology (SEQ Tech®) in a topical formulation. The Company expanded its offering with the introduction of 30g and 100g pack sizes for FlexiSEQ, an equine version under the brand name Nanoflex in the U.S and a CBD Oil product. The business also continued to expand into new geographies, particularly in Asia and the Middle East through distributors.
AMERICAN SOCIETY OF HEMATOLOGY (ASH) CONFERENCE
Ascension will be presenting a poster at the 63rd annual gathering of the American Society of Hematology in Atlanta, Georgia from 11th -14th December 2021 headlining interim results from the inhibitor arm of the SelectAte Phase 2 study. Further information will be announced in due course, and anyone interested in meeting the Company should contact Consilium Strategic Communications on the details below.
Biresh Roy, Chief Executive Officer
info@ascension.co.uk
Consilium Strategic Communications (European Media and Investor Enquiries)
Lindsey Neville, Ashley Tapp
ascension@consilium-comms.com
About Ascension Healthcare plc
Ascension Healthcare plc is a clinical-stage biopharmaceutical company focused on developing and commercialising innovative therapies for the treatment of haemophilia and osteoarthritis. The Company has three products in clinical development for the treatment of Haemophilia A and also a range of internationally marketed products for osteoarthritis sufferers.
For more information please visit: www.ascension.co.uk/
About Haemophilia
The Company's product development programmes are focused on treating a form of haemophilia, haemophilia A ("HA"), a congenital bleeding disorder which leaves a patient at risk of uncontrolled bleeding due to a lack of blood clotting Factor VIII ("FVIII"). HA is the most common form of haemophilia, affecting 80% - 85% of the total haemophilia population. HA has a prevalence rate of about 1 in 10,000 births and can be categorised from mild (5-40%) to moderate (1-5%), to severe (<1%) circulating FVIII depending on the actual level of functioning FVIII in the body.
The Company has developed and acquired intellectual property over several years (PEGylated liposomes and PEGylated blood proteins) with the intention of developing novel products for haemophiliacs, principally to deal with problems relating to the development of inhibitors in severe haemophiliacs, the lack of a convenient, safe, effective and economical prophylactic treatment administered by subcutaneous injection for severe haemophiliacs and
the need for a prophylactic treatment to boost existing FVIII levels in moderate and mild HA patients.
About FlexiSEQ
FlexiSEQ is a topical gel designed to support joint health and mobility. Unlike many topical gels for joint pain, FlexiSEQ is drug-free so can be used long-term by patients who are sensitive to, or cannot take, traditional pain medications. Ascension's patented Sequessome® technology (SEQ Tech®) contained within FlexiSEQ's topical formulation means that FlexiSEQ is safe and drug-free. User experience and clinical studies have shown significant benefits for users in improved joint health, mobility, and a reduction in the need for painkillers leading to an improved quality of life.
Find out more by visiting: https://flexiseq.com/pages/about
LONDON (AP) — Anti-poverty organization Oxfam called Monday for governments to impose a one-time 99% tax on the world's billionaires and use the money to fund expanded production of vaccines for the poor — part of an effort to combat global inequality widened by the coronavirus pandemic. The ranks of the super-rich have swelled during the pandemic thanks to ample financial stimulus that pumped up stocks, the group said. Meanwhile, poor countries have suffered more than their share from COVID-19

redpajama_set_name: RedPajamaCommonCrawl


text:
About AARP in Jackson
Mississippi Family Caregivers Provide $4.7 Billion in Unpaid Care to Family, Friends at Home
In Mississippi, approximately 470,000 family caregivers provided an estimated 400 million hours of care — worth a staggering $4.7 billion — to their parents, spouses, partners, and friends in 2017, according to state data available in the latest report of AARP's Valuing the Invaluable series.
The complexity of family caregiving increases as medical and nursing tasks continue to enter the home, and family demographics change amidst an aging population.
"Mississippi's family caregivers are invaluable to those they support," said AARP Mississippi State Director Kimberly L. Campbell, Esq. "AARP Mississippi is committed to advocating for family caregivers to get the support they need."
AARP is fighting to support family caregivers and the older family and friends who count on them. After AARP Mississippi's advocacy in the 2019 state legislative session, residents will be protected by the GAP (Guard and Protect) Act, which takes effect Jan. 1 next year.
Under the law, court-appointed guardians and conservators may represent at-risk adults who can no longer make decisions; these representatives will do so concerning property, medical care and potentially all personal and financial issues. The legislation updates current law and is meant to protect older adults from abuse and exploitation.
In 2020, AARP will continue to fight for commonsense solutions to give family caregivers more support, help at home, training and more.
To review state figures and the methodology, visit: www.aarp.org/valuing.
Resources and information on family caregiving, including AARP's Prepare to Care Guides, are available at www.aarp.org/caregiving.
This story is provided by AARP Mississippi. Visit the AARP Mississippi page for more news, events, and programs affecting retirement, health care, and more.
More from AARP in Jackson
Jackson Happenings | Upcoming AARP Events | About AARP
Jackson Happenings
DST Convention Prepare to Care
Jackson Convention Center
Central MS Volunteer Meeting
AARP MS State Office
Ridgeland, MS
An ally on the issues that matter most to you in Jackson


text:
In geology and climatology, a pluvial is either a modern climate characterized by relatively high precipitation or an interval of time of variable length, decades to thousands of years, during which a climate is characterized by relatively high precipitation or humidity, Subdivisions of a pluvial, which are characterized by relatively high precipitation, are known as a subpluvials. Formally, pluvials were equated with glacial stages of the Quaternary. However, pluvials, as in equatorial regions, can also occur during interglacial stages. Lower latitudes have even experienced major pluvials in early to mid-Holocene times.

In geomorphology, a pluvial refers to a geologic episode, change, process, deposit, or feature that is the result of the action or effects of rain. Sometimes, it also refers to the fluvial action of rainwater flowing in a stream channel, including a flood, known as a pluvial flood, that is the direct result of excessive precipitation.

See also

Abbassia Pluvial
Carnian Pluvial Event
Mousterian Pluvial
Neolithic Subpluvial
Pluvial lake

References

External links
The Geological Evolution of the River Nile, by Rushdi Said

Climatology
History of climate variability and change
Prehistoric Africa


Derek is a practising Barrister, Arbitrator, Adjudicator Mediator and Expert Witness as well as a Chartered Quantity Surveyor.
His career in the construction industry has spanned decades working for contracting and consultancy organisations in the UK and overseas including the USA, Canada, Germany, Switzerland, Belgium, Italy and in Saudi Arabia with French, Italian and Korean contractors.
Derek's early experience in the architectural field included eight years spent in the planning, design and on and off-site supervision of major housing schemes. This was followed by a career move into quantity surveying, firstly in housing, but later, and more predominantly, into the industrial and commercial sectors.
His contracting experience with major UK and French international building and civil engineering companies was broad and he advised UK design and build contractors and specialist structural steelwork companies, on contracts with values in excess of £1,500 million.
Derek's current consultancy experience involves the management and resolution of construction and engineering disputes by negotiation, mediation, conciliation, adjudication, litigation and arbitration, with disputed amounts in excess of £40 million.
Derek prepares Expert Reports on behalf of clients in contemplation of litigation and arbitration. He has acted as an expert witness in construction disputes on multi-million pound quantum matters and planning inquiries and been subject to cross-examination by Counsel in arbitration and the TCC.
Derek has been appointed as Adjudicator to on a £3m dispute on a holiday centre complex concerning the supply and erection of modular units relating to alleged delays and consequent losses and damages.
'An experienced practitioner who advises on a range of construction matters. He is also qualified as a chartered surveyor.
Derek Pye is qualified to accept instructions directly from members of the public and professional clients under the Direct Public Access scheme.


text:
Q: Referencing InfoWindowLite in JavaScript I am trying to add in the info window function using JavaScript. Besides that, I have added in FeatureLayers, a Legend and Scalebar. However, the moment I try to add in my InfoWindow, everything disappears when I try to run it in chrome. I am aware that the sequence that the attributes are placed in the JavaScript matters, but I have no idea where to paste the InfoWindow. I am using Notepad++.
Here's the code before I attempted to add in the InfoWindow.
<!DOCTYPE html>

<meta http-equiv="Content-Type" content="text/html; charset=utf-8">
<meta name="viewport" content="initial-scale=1, maximum-scale=1,user-scalable=no">
<title></title>
<link rel="stylesheet" href="http://js.arcgis.com/3.9/js/esri/css/esri.css">
<link rel="stylesheet" href="http://js.arcgis.com/3.9/js/dojo/dijit/themes/claro/claro.css">

     This pane could contain tools or additional content

and here's the code after I tried to add in the references for the InfoWindow (whereby everything disappears)
    <!DOCTYPE html>

    <meta http-equiv="Content-Type" content="text/html; charset=utf-8">
    <meta name="viewport" content="initial-scale=1, maximum-scale=1,user-scalable=no">
    <title>Mock Practical</title>

    <link rel="stylesheet" href="http://js.arcgis.com/3.9/js/esri/css/esri.css">
    <link rel="stylesheet" href="http://js.arcgis.com/3.9/js/dojo/dijit/themes/claro/claro.css">

     This pane could contain tools or additional content

Any help would be greatly appreciated. Thanks!

A: require path of this widget  is "esri/dijit/InfoWindowLite" instead of "..infoWindowLite"


Whether launching a product, growing a brand, cultivating an audience or building support for a cause, it takes a cohesive strategy and compelling message to successfully achieve your goals. Are you working with an innovative thinker to devise a plan and creative writer to implement it? You can.
From conception through execution, my strategy experience and copywriting skills can turn ideas into realities, engagement into action, and clicks into sales—no matter the medium or platform, KPI or target demo.
Welcome to the online home of Alex Mizrahi, where you'll find examples of my work (password protected; don't be shy, say hi!), articles I've written and more.


The XOMO EXO-Armor TC Box Mod was designed by SJC and XOMO.
The XOMO EXO-Armor is a high-end regulated mod developed over 1 year ago. The mod itself has a durable polycarbonate outer which fits 9 magnetic armor plates to it increasing the scratch and shock resistance. Additional Armor plates are available to customize your mod.
Powered by a Yihi Chipset, you can customize most features and themes to your preference on the circular TFT HD screen. The EXO-Armor even tells the time! Paired with upgradable firmware and 2A fast charge, it's a match made in heaven.
The stars on the golden ring around the screen are glow in the dark, so it's easy to see where your mod is in the dark, paired with the 3-colour LED backlight, the XOMO Exo-Armor is sure to stand out from the crowd.
The XOMO Exo-Armor supports VW, TC and TCR Modes, and its SXi-Q Intelligent Taste Curve has up to 5 options for optimum flavor.


text:
@Version("1.6.0")
package org.apache.jackrabbit.oak.commons;

import org.osgi.annotation.versioning.Version;

redpajama_set_name: RedPajamaGithub


text:
Tracy Silverman Brings Electric Violin to the CSO for 'The Dharma at Big Sur'
Tracy Silverman rejected a career as a classical violinist, but paved his own playing electric violin.
By Anne Arenstein on Mon, Oct 1, 2018 at 5:31 pm
Martin Cherry
Tracy Silverman
Tracy Silverman's nonconforming approach to his music is an integral part of his psyche. He rejected a career as a classical violinist, switched to the electric violin and stopped listening to its two biggest exemplars, Stéphane Grappelli and Jean-Luc Ponty — turning to Rock and Soul giants Jimi Hendrix, John Coltrane, Miles Davis and Aretha Franklin for inspiration.
Silverman will make his Cincinnati Symphony Orchestra debut this weekend performing The Dharma at Big Sur, a work that he says, "never ceases to affect me." Although it's his first performance here, the CSO performed Dharma 10 years ago with composer John Adams on the podium and soloist Leila Josefowicz. But Josefowicz was an acoustic violinist adapting to an electric instrument. Silverman perfected the sound on electric violin for over two decades when Dharma debuted.
When Silverman broke with his classical violin rep he figured his days as concert hall performer were over. But in 2002, Adams heard Silverman playing at an Oakland, Calif. Jazz club. At the time, Adams was writing a concerto for the opening of Walt Disney Concert Hall in Los Angeles (designed by Frank Gehry); Silverman's playing inspired what became Dharma, which premiered in 2003 with Silverman as the soloist, and Esa-Pekka Salonen conducting the Los Angeles Philharmonic.
A ceaseless explorer of sonic innovation and synthesis, Silverman has brought the electric violin into virtually every genre of music; he's also designed instruments and pioneered techniques that are standard for today's electric violinists. His lengthy discography features him as soloist, guest artist, composer, arranger or producer.
After 35 years with the electric violin, Silverman understands why the instrument still might be a hard sell.
"I spent a lot of years in Rock bands and it's easy for people to think this is something flashy," he says, speaking from his home in Nashville. "But my goal is serious and maybe more boring but that's what I'm trying to do."
What Silverman plays is not an acoustic violin with a pickup. He designed his first violin — a six-string solid-body model resembling a mini-Fender Stratocaster in the early '80s — while working with fellow-violinist Mark Wood, who Silverman calls "a true visionary." (Wood Violins just celebrated its 25th anniversary.)
Every Silverman instrument is designed for the widest palette of sounds and he provides a vivid rationale in his artist statement: "My demands on the instrument range from Jimi Hendrix's wailing distortion to Miles Davis' intimate jazz, Salif Keita's emotional Malinese vocal style to Brazilian samba grooves, Indian classical inflections and 'just' (or 'pure') intonation."
Although this statement was written in 2017, it speaks to a commitment spanning three decades that led to Dharma and a return to the concert stage.
Silverman was part of an ensemble led by the minimalist composer Terry Riley when John Adams first heard him. "Tracy's unique style was a marvel of expressiveness," he wrote in the liner notes to the 2003 recording on Nonesuch. "When I listened to Tracy play I was reminded that in almost all cultures other than the European classical one, the real meaning of the music is in between the notes."
Describing Dharma, Silverman gives a shout-out to Adams' penchant for taking risks, not only musically, but also on Silverman himself.
"He could have had anyone much more famous to play it and he took a chance on me, a virtual unknown," Silverman says. "But he was true to his artistic vision. He wanted a California synthesis of that's unafraid to blend all these musical elements and doesn't care about names."
Dharma was inspired by Adams' first encounter with the spectacular California coastal landmark and by his friendship with West Coast composers Lou Harrison and Terry Riley. Adams creates a brilliant fusion of Eastern and Western musical forms using the electric violin's meditations and ecstatic dancing phrases.
Silverman points out that Adams also took a risk with the orchestra, originally writing the piece for 'just' tuning, meaning different intervals between the notes differently tuned than in the conventional manner. This proved too difficult for an entire orchestra, so adjustments were made for subsequent performances.
"Synthesizers and two harps will play in 'just' tuning, and as much as possible, so will I," Silverman says. "It gives me the kind of resonance you hear in Indian music."
The first part entitled "A New Day" begins with a low drone as the violin emerges in the style of the alap, an improvisation that introduces a melody in a raga.
"That opening arc to me is a like a Rumi poem, with incredible strength, power and simplicity," Silverman says. "And the simplicity makes it more profound."
The momentum picks up in the second movement, "Sri Moonshine," with more dance-like, pulsing rhythms. The solo violin passages are like a seagull's swoops over the ocean and, as the intensity builds, the orchestra builds to an ecstatic crescendo.
The CSO performances will be accompanied by a video created by Adam Larsen.
"His work is breathtakingly beautiful and wonderfully supports this sense of being alone with nature," Silverman says.
Dharma remains evergreen for Silverman. "I've heard it thousands of times and practiced it tens of thousands of hours and it still affects me. The textures of the score are just thrilling"
"It's very personal," he continues, "There's this sense of being in touch with your deepest relationship with the universe and how connected we are."
Silverman has several more performances of Dharma throughout the fall. He's delighted that the work is now considered standard repertoire and he's even happier that there are more musicians who perform it.
"I used to be the only guy doing it and now I'm not!" he says with a laugh. "If I've accomplished anything, I hope it's to open up this area to future generations. There are so many things it can do that an acoustic violin can't."
Violinist Tracy Silverman performs The Dharma at Big Sur with the CSO Oct. 5 and 6 at Music Hall. Tickets: cincinnatisymphony.org.


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Patricia A. Jennings is a Professor of Education at the University of Virginia.

Education and early career
Patricia A. Jennings received a BA from Antioch College in 1977, an M.Ed. from Saint Mary's College in 1980, and a Ph.D. from the University of California Davis in 2004. Before her degrees in education and human development, Jennings also studied Buddhism at the Buddhist Naropa Institute in Boulder, Colorado, and later founded a Montessori school that taught meditation during the late 1980s.

Research
She was an associate professor at the Curry School of Education, University of Virginia until 2019, when she was promoted to Full Professor. She has also served as a Research Assistant Professor at Pennsylvania State University. Jennings's book Mindfulness for Teachers: Simple Skills For Peace And Productivity In The Classroom, was published in 2015.
Jennings is to co-creator of the Cultivating Awareness and Resilience in Education (CARE) program, a thirty-hour mindfulness-based professional development program. The goal of the program is to help Pre-K-12 teachers deal with in-class stress. It was tested in a clinical trial in 2017, which involved 224 elementary school teachers, evaluating the program through teacher questionnaires and classroom observations. The results of the research showed that CARE can "increase teacher social and emotional competence and the quality of classroom interactions," according to the New York Times. It was the largest study of its kind to date at the time. Following this, she worked on the Compassionate Schools Project research project, intended to teach and provide mindfulness skills to elementary students.

In 2018, she received the Catherine Kerr Award for Courageous and Compassionate Science.

Her book The Trauma-Sensitive Classroom was then published in 2019. Jennings is a member of the National Academy of Sciences Committee on Fostering Healthy Mental, Emotional, and Behavioral Development among Children and Youth.

References

Living people
Antioch College alumni
Saint Mary's College of California alumni
University of California, Davis alumni
Naropa University alumni
University of Virginia faculty
American education writers
Year of birth missing (living people)


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Stuart A. Sears is a talented trial attorney with a broad range of experience representing individuals and companies in high-stakes and often high-profile white-collar investigations, congressional inquiries, criminal prosecutions and related civil and administrative proceedings. He has represented U.S. and foreign clients in global investigations involving the Foreign Corrupt Practices Act (FCPA), the False Claims Act, criminal antitrust allegations, fraud, and national security matters. Mr. Sears has been recognized by Best Lawyers, Super Lawyers, and Washingtonian Magazine as a top tier criminal defense and white-collar lawyer.
Over his career, Mr. Sears has earned a reputation for a being a zealous and persuasive advocate for his clients. His credibility and judgment have been recognized by opposing counsel, judges and peers. Whether it's presenting to the government, a judge, or a jury, Mr. Sears is regarded for his ability to communicate his client's story in a simple, effective and convincing manner.
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Before entering law school, Mr. Sears worked in the financial services sector at a large corporation in Boston, Massachusetts. He later attended the American University, Washington College of Law where he graduated cum laude. Stuart is an active member of the National Association of Criminal Defense Lawyers and the Virginia Association of Criminal Defense Lawyers.
Stuart has been recognized for his litigation skills by several publications, including:
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JetsInsider.com > Articles by: Bennett Sterrer
How to Spend $100 Million Dollars for Sam Darnold
The Jets have a bright future if they play their cards right this offseason. The good thing is, the Jets have about $100 million cards as of right now, and a very high draft pick. I ran a free agency simulator to see just what the Jets can do this offseason. First, then I would…
Jets Lose 44-38 in OT After Blowing 4th Quarter Lead
The Jets lose a wild one in overtime 44-38 after a 16-yard dime pass from Aaron Rodgers right into the breadbox of Davante Adams sealed the deal. To get their first road win of the season, the Packers needed a lot of help from the Jets defenders, and they got it- the Jets had 16 penalties…
Todd Bowles Out, Who's Up Next?
Bowles' tenure as head coach started with so much promise- the team went 10-6 and barely missed the playoffs because of shoddy quarterbacking from Ryan Fitzpatrick. Decker and Marshall were having 100-yard games regularly and the defensive line featuring Muhammad Wilkerson, Damon Harrison, Sheldon Richardson, and newcomer Leonard Williams was causing a disturbance in the…
Slider,
The Jets Annual Talent Search is Officially Underway
Hardened Jets fans know what time of year it is. While the rest of the season does not matter for playoff implications, there is still football to be played. People are starting to look forward to the draft and the impending $100 million dollar spending spree. The Jets players have three games left to prove…
Jets – Texans Preview
The Jets play the 9-4 Texans this Saturday after the Texans lost for the first time in nine games, a 24-21 loss to the Colts. The Jets are fresh off their first divisional win this season, a 27-23 revenge win over the Bills, who trounced the Jets in their last clash. The Jets played tough…
Jets Edge Bills 27-23 In Meaningless Classic
Orchard Park, NY – The Jets won a thriller on Sunday in western New York, where frigid temperatures and a re-injuring of his sprained foot failed to keep Sam Darnold from getting the win. He showed a lot of chutzpah on the game winning drive, throwing for 51 of the 66 yards gained on the drive…
The Cost-Benefit Analysis of Playing Sam Darnold
Florham Park, NJ – Sam Darnold is recovering from a sprained foot, and the injury was bad enough that he had to wear a boot. For the average person it takes six to eight weeks to recover from a sprained foot, and Darnold is in his fifth week of rehabilitating the injury. He should be just about…
Williamson Could Lead Enigmatic Jets to a Win Against Talented Titans
It has been almost four years since winning (losing?) the Mariota bowl, a mid-December affair featuring a 3-11 Jets square off against a 2-12 Titans that the Jets ultimately won, and it costed them a couple picks in the 2015 draft. The Titans took Mariota second overall, while the Jets had to "settle" on Leonard…
JETS – PATRIOTS PREVIEW
The Jets are looking to change the narrative of this season and keep Todd Bowles job, and to accomplish both of those things they must beat New England this Sunday. Each team experienced a demoralizing loss the previous week and will be looking to return back to their peak form. When: Sunday, November 25th,…
Barkley Batters Jets for 41 Points in Brutal Beatdown
East Rutherford, NJ– The Buffalo Bills annihilated the New York Jets today, 41-10. The Barkley-led Bills dropped a forty burger on the Jets, and hardened Jets fans were forced to search for a time when they felt more embarrassed to bleed green and white, as the boo birds were out in force before halftime. Coming into…


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� Home About Archive Moved, and thank you. Also on Micro.blog
📚 Book Review: The Gatekeeper, by Nuraliah Norasid.
The Gatekeeper, by Nuraliah Norasid. Read July 2018.
An urban fantasy novel set in a world heavily reminiscent of Singapore. Norasid is a Muslim Singaporean author, and this novel won two literature prizes in 2016 and 2018.
The story follows Ria and Eedric, two characters who, amongst other things, are racial minorities – Ria is fully non-human, and Eedric is of half-human, half non-human parentage. Both characters face ongoing prejudice and ostracism that comes from being of an unacceptable, defeated bloodline. The story is about their struggle against a ruthless world and the increasing gulf between the majority culture and their minority status. While there are moments of brightness and hope, the story has a fatalistic overtone and ends bleakly. But not unsatisfactorily – this bleak ending is a prompt for reflection about one's own assumptions about race, culture, and the position of minorities within a majority culture.
This book is of particular interest to me because I was Norasid's countryman. The Gatekeeper is steeped in South-east Asian culture: the history and setting of Manticura is reminiscent of Singapore's own history, Ria and Eedric are representations of the indigenous Malay people prior to Chinese and European colonization. The novel contains a subtext of highlighting and critiquing the progress of Singapore from pre-colonial to colonial to independence to modernity, and also the social ills and complexities of inter-cultural and interracial matters in modern Singapore. The dialogue is written in the colloquial English of the region, rife with "Singlish" grammar and Malay words. When I read the dialogue, in my mind I also heard it spoken out loud in an accent well familiar to me.
Reading this book was an interesting experience. Norasid uses a fantasy setting to put distance between the reader and the cultural commentary on the real-world, to "make strange" the reality of the world so that we can see issues that would otherwise be camouflaged in normalcy. The cultural commentary was clarion and prompted my own reflection (I've experienced both sides of the racial-cultural majority/minority divide), but more than that, I was captivated by the juxtaposition of familiarity and strangeness of Manticura-Singapore. In some ways, that's how I feel every time I go back to the region: it's familiar, but also strange, and I'm now a foreigner in a place where my roots were – and perhaps, still are.
Vega @vega


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According to our database1, Michal Kania authored at least 10 papers between 2011 and 2017.
Prediction of the Exit Site of Ventricular Tachycardia Based on Different ECG Lead Systems.
Improved robust T-wave alternans detectors.
T-P Interval Estimation in Case of Overlapping Waves.
The effect of precordial lead displacement on ECG morphology.
A simulation of T-wave alternans vectocardiographic representation performed by changing the ventricular heart cells action potential duration.
The Effect of Precordial Lead Displacement on P-wave Morphology in Body Surface Potential Mapping.
T waves segmentation and analysis using inverse normalized integrals.


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Cowbridge Livestock Market
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Q1 Tracking
Home > our_council > Council Structure > minutes,_agendas_and_reports > Q1 Tracking
Agenda Item No. 8
Corporate Performance and Resources Scrutiny Committee: 1st September, 2016
Report of the Managing Director
1st Quarter Scrutiny Decision Tracking of Recommendations and Work Programme Schedule 2016/17
Purpose of the Report
To advise Members of progress in relation to the Scrutiny Committee recommendations and to confirm the work programme schedule for the Scrutiny Committee for 2016/17:
From previous Scrutiny Committee (Corporate Resources) Municipal Year 2014-15 (Appendix A)
1st Quarter April - June 2016 [April from previous Scrutiny Committee (Corporate Resources] (Appendix B)
Work Programme Schedule for 2016/17 (Appendix C).
That the views of the Committee on the status of the actions listed in Appendices A and B to the report be sought.
That the work programme schedule attached at Appendix C be approved and uploaded to the Council's website.
Reasons for the Recommendations
To maintain effective tracking of the Committee's recommendations.
For information.
An integral part of effective scrutiny is a mechanism for Scrutiny Committees to monitor their recommendations to ensure that desired actions are carried out and where necessary progress is reported back.
The work programme schedule provides a breakdown of reports anticipated to be considered by the Scrutiny Committee over the forthcoming months.
Relevant Issues and Options
Appendices A and B attached to this report set out the recommendations of the Scrutiny Committee and Members are requested to review progress against each recommendation, to assess whether further action may be required, ensure the required action is undertaken and to confirm which recommendations are to be agreed as completed.
Where appropriate, progress on actions relating to a service area covered by a previous Scrutiny Committee are now included in the Appendices for the appropriate Committee's consideration.
It is important that decisions of Scrutiny Committees are tracked and monitored as failure to do so could result in a risk that recommended courses of action will not be followed and consequently lost. This would undermine the credibility of the scrutiny process.
Members are also requested to confirm approval of the Scrutiny Committee Work Programme Schedule attached at Appendix C, it being noted that the schedule is a proposed list of items for consideration and may be subject to change depending on prevailing circumstances.
The work programme has been aligned to the Cabinet Forward Work Programme. The Scrutiny and Cabinet Roles and Responsibilities Protocol Point 7.6 states it is essential that the Cabinet Work Programme is taken into account when Scrutiny Committees are drawing up their own Work Programmes and also details reports that have been requested by the Scrutiny Committee together with items that require regular monitoring and scrutiny. Other reports will be added to the schedule as and when necessity arises. The schedule will also detail Requests for Consideration that have been received and the consideration given by officers of the likely date they can be reported to the relevant Committee. With regard to Call-in Requests that are made following decisions of Cabinet, as these are required to be dealt with within 20 working days of a Cabinet decision (as per the Council's Constitution) , they will be included within the programme as and when received.
With regard to Task and Finish work, the Council is in the process of agreeing a suite of measures to monitor progress against the new Corporate Plan wellbeing Outcomes which will be considered by Cabinet shortly. This work is being informed by the Member Working Group and Task and Finish discussions will commence thereafter.
The work programme can also be found on the Council's website at the following link: http://www.valeofglamorgan.gov.uk/en/our_council/council/scrutiny/scrutiny_committees.aspx.
Resource Implications (Financial and Employment)
None as a direct result of this report.
Sustainability and Climate Change Implications
Legal Implications (to Include Human Rights Implications)
Crime and Disorder Implications
Equal Opportunities Implications (to include Welsh Language issues)
Corporate/Service Objectives
Scrutiny contributes to all Corporate and Service Objectives contained in the Corporate Plan and there is also an important role for Scrutiny to play in monitoring the progress for delivering these objectives. There is also an integrated planning action contained in the Corporate Plan for 2016 "Review the current arrangements to support effective scrutiny and facilitate more robust challenge and improved accountability" of which this Work Programme forms a part.
Policy Framework and Budget
This report is in accordance with the recommendations of the WAO Democratic Renewal report and acknowledges the recommendations of the review of the Council's scrutiny function.
Consultation (including Ward Member Consultation)
Not applicable given the issue is an internal matter.
Relevant Scrutiny Committee
Relevant Scrutiny Committee and Cabinet minutes.
Contact Officer
Jeff Rees, Principal Democratic and Scrutiny Services Officer, Tel: (01446 709413)
Officers Consulted
Jeff Wyatt, Operational Manager (Democratic Services)
Responsible Officer:
Rob Thomas, Managing Director


The Autumn Birds group flocked up the hill towards me, buzzing with anticipation for what the evening may hold. Brimming with badger and pine marten trivia, and anxious not to disappoint on the first hide visit that I had ever run, I waited. The evening certainly did not let me down.
As we stood in the fading light outside of the Magnus House, sharing news of the day's fantastic wildlife sightings, we witnessed our first nocturnal hosts; bats! They swooped past along the path and tree line, carrying out daily commutes between hunting grounds and roosts. Five species of bat have residence on site: Natterer's (Myotis nattereri); Brown Long-eared (Plecotus auritus); Common and Soprano Pipistrelles (Pipistrellus pipistrellus & P.pygmaeus); and Daubenton's (Myotis daubentonii). Some lucky individuals seemed to have discovered the delights of the moth trap set that night at the edge of the woodland, and were taking advantage of the insects that were circling the light in misplaced navigation attempts.
The calls of migrating Pink-footed Geese (Anser brachyrhynchus) rang above as they filled the autumn sky in their triangle formations. At this time of year, they can been seen in their thousands on local mudflats and grazing fields.
Barely had we all settled down in the hide, when bounding towards the feeders came our first visitor, a pine marten. I recognised her bib; Polly, a rescued orphan released on site the previous year. Much to our delight, she put on quite the show, munching down not only most of the pine marten bait, but also some of that intended for badgers. She stayed for over twenty minutes before the unexpected bleat of a nearby sheep caused her to slink away into the darkness. Calls of the night filled the air; the deep husky barking of a young red deer followed by the sombre hoot of a tawny owl, perhaps one of this year's fledgelings.
Moments later a badger scampered its way into view carelessly tossing aside stones to inhale its food. As winter is rapidly encroaching on nature, both the pine martens and badgers are desperately stocking up. This was evident that night when less than half an hour later I was saying "Ok everyone so the bait has been polished off… we may not attract in anything else this evening, but I'd call that a pretty successful evening". Of course, everyone left delighted with what they'd seen, and turned in for an unexpectedly early night. For some it had been their first viewing of Scotland's wonderful nocturnal wildlife, as it had been for me only a few weeks previously.
Written by Academic Placement, Jessica Stokes. Image of pipistrelle bat by Laurie Campbell. Images of badger and pine marten at the Aigas hides by Pete Short.