Does Jakafi contribute to deadly mutations?
There is a smoking gun. But no fingerprints. Yet.
Nevertheless, among a group of patients who discontinued Jakafi during its 2007-2011 pre-approval clinical trial stages, there were deaths, transformation to acute myeloid leukemia and the emergence of high risk mutations.
The raw numbers themselves are chilling.
Kate Newberry and her colleagues at MD Anderson undertook a retrospective review of the 107 patients enrolled in the Phase 1/2 clinical trial of ruxolitinib (later to be called Jakafi) at its Houston site during the 2007-2011 period. Almost all — 95 patients — discontinued treatment and of that group 86 patients were available for follow-up analysis.
For Newberry, a young research scientist these were all data points derived from a study that ended years before she joined MD Anderson.
Her boss, Srdan Verstovsek, and several colleagues however had been deeply involved in the years of Jakafi clinical trials and the clinical and educational processes that followed after FDA approval in 2011. For them, these were 86 people they saw in the halls and clinics and a project closely associated with their professional careers.
30 patients on that trial died while on therapy and were excluded from the post-discontinuation analysis. As a result we don't know what new mutations they may have harbored. That left 56 patients for the MD Anderson group to follow… but not for very long. The median survival after discontinuing Jakafi was only 14 months.
The MD Anderson group took a deep dive into the data to get a clearer idea of what was going on. They had molecular data for 62 patients both when they entered the clinical trial and when they quit.
The comparison revealed roughly one-third of them had acquired new mutations while taking ruxolitinib. Worse, a whopping 61% of those mutations were in ASXL1, a High Molecular Risk (HMR) gene with awful survival prospects.
The gain in mutations, called clonal evolution, could be ominous. Overall survival for patients experiencing clonal evolution was only six months versus 16 months for others who discontinued Jakafi therapy while trial.
The question is: Did Jakafi cause these new mutations, this clonal evolution?
To get the answer, here's the required background, the evidence, and the witnesses.
Jakafi (ruxolitinib) is the standard therapy for intermediate and high risk myelofibrosis. Since its FDA approval in 2011 it has changed pretty much everything. .
Jakafi inhibits the interaction between a mutated JAK2 protein—the clone — an enzyme active in, among other things, blood production, and the STAT, the Signal Transducer and Activator of Transcription proteins. Essentially, the Jak2 mutation flips the blood production switch into the ON position and the STAT enables the message to get to the cell nucleus where the production order is carried out.
One frequent result is increased fibrosis of the bone marrow marrow, literally myelofibrosis. Blood production may then be forced out of its blood-bone marrow niche to more hospitable quarters, notably the spleen. This produces swelling of the spleen causing pain and impacting movement, digestion, quality of life.
When good news may be bad.
When Jakafi works – which, in the beginning, for most patients, is most of the time – it causes rapid reduction of splenomegaly and a vastly improved quality of life. That's very good news short term. But the Jakafi effect doesn't last forever – usually less than three years. And during all this time, the patient feels better while the underlying disease continues to progress and the JAK2 clones thrive.
That's bad news since simply feeling better is all the reason most patients need to avoid the rigors of the only curative therapy for MF: stem cell transplant. Too often that mean delayed entry to transplant and reduced odds of success.
There may be a much more lethal aspect to Jakafi therapy.
The study by Kate Newberry, Srdan Verstovsek and their MD Anderson colleagues revealed about one-third of the patients who discontinued Jakafi for one reason or another had acquired High Molecular Risk mutations in other genes. And over 60% of those mutations were in the dreaded ASLX-1 gene. Overall life expectancy for this group was under 14 months.
Now we can call on expert witnesses to testify on what may have caused this deadly surge in mutations.
The chief investigator who should know – Dr. Srdan Verstovsek, a leading and long-term researcher into ruxolitinib, professor in the MD Anderson Department of Leukemia, Director of the Clinical Research Center for MPNs at MD Anderson and co-author of the latest piece of evidence –doesn't believe Jakafi is guilty. Neither does his co-author colleague, Kate Newberry – now up in Boston working on a lymphoma project with her new crew at Epizyme.
University of Florence and on the board of International Working Group for Myelofibrosis Research and Treatment, noted in a comment in Blood that transfusion dependence among those patients who discontinued Jakafi had increased from 29% TO 43% and both hemoglobin and platelet counts had significantly reduced compared with the start of their Jakafi therapy.
Both Verstovsek and Newberry agree. Yes, those are signs of disease progress and hematologic toxicity.
"It depends on timing of the observation," said Verstovsek.
"There are two phases here. Anemia and thrombocytopenia happen during the first six months of Jakafi treatment. It's a period during which we have to adjust dosage for 75% of patients. Then once you have a stable patient the appearance of anemia and thrombocytopenia are indications of progressing disease.
Newberry concurs: "As the disease progresses, it's just a natural process. These mutations are seen in MPN disorders and leukemia in general. You see them in patients who have never taken ruxolitinib.
"I think ruxolitinib is innocent. I actually do. If I recall, the patients who have clonal evolution may have been worse off when they started the therapy, more prone to anemia, more likely to become transfusion dependent. My sense is they suffered a more aggressive disease.
'But ruxolitinib can exacerbate some of the symptoms of the disease, that's for sure. I agree with that. It's hard to say what the mechanism is. Nobody has looked directly at what ruxolitinib is doing to these cells. That's hard to do with the patient data.
Regardless of the process, whether Jakafi accelerated, exacerbated, or promoted the natural emergence of high risk mutations it appears likely Jakafi contributed to the development of clonal evolution in the group of patients studied by the MD Anderson group.
The evidence is circumstantial and far from decisive but compelling. These high molecular risk mutations may indeed eventually appear in the MPN patient population but the relatively short time span in which they arose in this patient population and the acquisition of these mutations by a large percentage of the cohort — with nearly two-thirds of those mutations in ASXL-1 — argues for the possibility of clonal evolution acceleration due to the drug.
Beyond that, Jakafi is non-specific. It is active in multiple processes involving cells that rapidly divide and present mutational opportunities. Jakafi not only inhibits the JAKv617v clone but the human JAK2 protein is involved in cell growth and development, differentiation and histone modifications. It mediates essential immune system signaling events.
The fact that patients reject Jakafi due to intolerance and the high rate of discontinuation on the COMFORT trials (50% over three years) suggests a likely toxicity. And the inability of Jakafi to be effective over time indicates incremental somatic rejection of the drug and its inability to continue enabling JAK2 recruitment and phosphorylation of STAT5 to transcribe genes.
For now, Jakafi is the best we have, and in some cases the only option beside stem cell transplant. Intermediate-2 and high risk MF patients will continue the rely on it even as its use stretches into applications for polycythemia vera and lower risk MF patients.
We can profitably use mutation analysis to direct Jakafi MPN therapy, particularly in PV and early stages of myelofibrosis.
Mutation screening by the numbers.
The major reasons for prior mutation testing before Jakafi therapy: Mutations in high molecular risk (HMR) genes ASXL1, EZH2, IDH1/w and SRSF2 are associated with: (1) inferior prognosis, (2) decreased spleen response, (3) shorter time to discontinuation, (4) greater likelihood of clonal evolution and have both (5) a negative impact on overall survival while (6) increasing the likelihood of leukemic transformation in MF. The presence of any of these HMR genes as well as any three or more mutations reduces the odds that Jakafi would be effective.
While Jakafi controls the symptoms and signs of myelofibrosis in the great majority of patients — and with that may prolong life expectancy — it does not prevent diseased cells from acquiring new mutations nor becoming resistant to ruxolitinib. This resistance leads to a loss of a control and poor overall outcome. Consideration of Stem cell transplant, the only potentially curative MPN option, needs to be on the table particularly when the patient is still doing well on ruxolitinib.
© MPNforum, LLC , MPNforum.com, and the MPNforum Quarterly Journal 2018. MPNforum is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. Reproduction is permitted provided full and clear credit is given to authors and MPNforum.com with appropriate and specific direction to the original content.


blessed to have you a part of our lives for the last year and half.
We are so proud of how far our daughter far has come.
confidence and self-esteem has seemed to soar.
"My experience with U-Learn Academy has been a positive one for my son and me. When we first came to U-Learn Academy my son was in the 4th grade, reading on a first grade level. He was behind in math also. He was on a 3rd grade level. We have been coming twice a week for a year. I can proudly say after a year my son has improved in his overall ability to read, in his self-esteem and his math skills. He is now helping other kids in his room with their math skills. His spelling has gone from D's to B's. My son is in the 5th grade and now for the first time he has made the honor roll. Ms. Jones provided me with a very positive learning experience for my son. The atmosphere was one conducive to learning…He is continuing to improve thanks to Ms. Jones and her fine staff. They are greatly appreciated."
"I am writing to express my gratitude and appreciation for the excellent tutoring services provided by you and your colleagues to some of our Camp Fire boys and girls over the past year.


text:
Blog posts and articles from the Royal Society
Schools Network
The move to fully Open Access – what about the author?
We believe that inability to pay article charges should not be a bar to publishing good science.
'To mitigate any problems with access to paywalled articles in low income countries, we partner with various international schemes in order to make our journal content freely available.'
Phil Hurst
Publisher, the Royal Society
Since our recent announcement to flip our hybrid research journals to a fully open access model when 75% of articles are being published open access, there have been plenty of discussions about the importance of maintaining a level playing field for authors.
Up to now these journals have operated on a so-called 'hybrid' open access model. Any researcher is free to submit an article and to choose whether to publish open access or behind a paywall. The author is also free to deposit their accepted manuscript in an open repository.
To mitigate any problems with access to paywalled articles in low income countries, we partner with various international schemes in order to make our journal content freely available to low-income and lower middle-income countries.
Access to authorship in fully open access journals
Hybrid open access is now seen by many funders as purely a transition to fully open access journals. There are many reasons for this which are beyond the scope of this blog post. Fortunately, many funders are supporting article payments either in direct reimbursement of article processing charges (APCs) or by contributing to 'transformative deals' in which read fees are combined with open access fees. Over time, these Read & Publish deals are expected to evolve into purely 'publish' deals as all content becomes open.
What if the author does not have funder support?
In some parts of the world and in some disciplines, authors have little or no funding for open access publication. We believe that inability to pay article charges should not be a bar to publishing good science and already makes provision for this in our two fully open access journals.
a. Corresponding authors based in low-income countries (classified as Group A or Group B by Research4Life) receive a full waiver of APCs.
b. Authors from outside these countries who may not be able to pay an APC can apply for a discretionary waiver. The author fills in a short form and the decision whether to grant a waiver is taken independent of the editorial decision-making process. If the author is able to demonstrate they have explored and exhausted suitable funding sources, the waiver is normally granted.
Why isn't open access free of charge?
Ultimately if scholarly communication is to meet the high standards expected by the research community there is a cost involved. We greatly appreciate the work of volunteers such as academic editors and reviewers without whom scholarly communication would not be possible. However, there is a range of costs including managing peer review (which of course includes the cost of all the rejected papers where no APC has been collected), electronic production, metadata, ethical checks, data hosting, editing, discoverability and dissemination.
What are the benefits of publishing open access?
We believe that opening the record of science to the widest possible audience and making that record re-usable will accelerate the generation of knowledge and accelerate discovery. We apply the same standards of high-quality, rapid peer review and production to all papers, whether or not they are behind a paywall.
Many researchers are now required by their funder or institution to publish their work open access, but in addition, authors who choose open access publication are likely to benefit from increased dissemination and citation.
If you choose open access, we will deposit the article in PubMedCentral on your behalf. You'll also benefit from a liberal licensing and re-use policy through Creative Commons licence CC-BY 4.0. This is vital to ensure others can build on your work while giving you credit.
Find out more about publishing open access with us.
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redpajama_set_name: RedPajamaCommonCrawl


text:
namespace stratum {
namespace p4c_backends {

// A HeaderValidInspector inspects one IR::Statement.  It usually begins
// an inspection with the "body" statement at the top level of a P4Control.
// As it inspects the IR nodes in the input statement, HeaderValidInspector may
// create recursive instances of itself to inspect deeper nodes in the IR.
class HeaderValidInspector : public Inspector {
 public:
  // The ref_map and type_map parameters come from the p4c midend output.
  HeaderValidInspector(P4::ReferenceMap* ref_map, P4::TypeMap* type_map);
  ~HeaderValidInspector() override {}

  // The Inspect method inspects IR nodes under the input statement.  For
  // any IR::IfStatements with a header.isValid() condition, it looks for
  // child nodes that apply tables, and it calls the table_mapper to update
  // table descriptors in the P4PipelineConfig as needed.  If Inspect detects
  // an unsupported combination of header validity checks, as described by
  // the file header comments, it reports a P4 program error using p4c's
  // ErrorReporter.
  virtual void Inspect(const IR::Statement& statement,
                       TableMapGenerator* table_mapper);

  // These methods override the IR::Inspector base class to visit the nodes
  // under the inspected IR::Statement.  Per p4c convention, they return
  // true to visit deeper nodes in the IR, or false if the Inspector does
  // not need to visit any deeper nodes.
  bool preorder(const IR::IfStatement* statement) override;
  bool preorder(const IR::MethodCallExpression* expression) override;
  bool preorder(const IR::AssignmentStatement* statement) override;
  bool preorder(const IR::TableHitStatement* statement) override;

  // HeaderValidInspector is neither copyable nor movable.
  HeaderValidInspector(const HeaderValidInspector&) = delete;
  HeaderValidInspector& operator=(const HeaderValidInspector&) = delete;

 private:
  // These types maintain the internal state of the Inspector.  A ValidHeaderSet
  // contains the names of all P4 headers with valid conditions in the current
  // scope.  For example, in the statement sequence:
  //  table1.apply();
  //  if (header2.isValid()) {
  //    table2.apply();
  //    if (header3.isValid()) {
  //      table3.apply();
  //    }
  //  }
  // The ValidHeaderSet is empty when table1 is applied.  It contains
  // {"header2"} when table2 is applied.  It expands to {"header2", "header3"}
  // before table3 is applied.
  //
  // The TableHeaderMap stores the ValidHeaderSet for each table the Inspector
  // has encountered.  The key is the table name.  After the inspection of
  // the sample statements completes, the TableHeaderMap consists of the
  // following pairs:
  //  {"table1", {}}
  //  {"table2", {"header2"}}
  //  {"table3", {"header2", "header3"}}
  typedef std::set<std::string> ValidHeaderSet;
  typedef std::map<std::string, ValidHeaderSet> TableHeaderMap;

  // This private constructor is for creating recursive instances only.
  HeaderValidInspector(P4::ReferenceMap* ref_map, P4::TypeMap* type_map,
                       bool reject_is_valid, bool reject_table_apply,
                       ValidHeaderSet* valid_headers_in_scope,
                       TableHeaderMap* table_header_map);

  // A HeaderValidInspector uses recursion to use separate scopes to visit
  // the two branches of an IfStatement.
  void Recurse(bool reject_table_apply, const IR::Statement* statement);

  // A HeaderValidInspector calls this method when it visits an IR node that
  // represents a table apply.
  void ProcessValidTableHeaders(const IR::P4Table& p4_table);

  // Inspects the input method_call to see if it is an isValid() expression
  // operating on a header type.  It returns the header name upon finding
  // an acceptable expression.  Otherwise, it returns an empty string.
  std::string FindValidHeaderCheck(const IR::MethodCallExpression* method_call);

  // These members store the injected parameters.
  P4::ReferenceMap* ref_map_;
  P4::TypeMap* type_map_;

  // A preorder method can set this value to forbid the appearance of
  // header.isValid() expressions in deeper nodes.
  bool reject_is_valid_;

  // This flag is true when HeaderValidInspector needs to reject table applies
  // in the false block of an IfStatement.  It records the value passed into
  // the private constructor for recursion.
  const bool reject_table_apply_;

  // These pointers refer to the internal Inspector state, as described for
  // the private typedefs above.  The top-level HeaderValidInspector creates
  // the instances for each inspection and maintains ownership in local
  // variables.  It hands them down to recursive instances to share a common
  // state.
  ValidHeaderSet* valid_headers_in_scope_;
  TableHeaderMap* table_header_map_;
};

}  // namespace p4c_backends
}  // namespace stratum

#endif  // STRATUM_P4C_BACKENDS_FPM_HEADER_VALID_INSPECTOR_H_

redpajama_set_name: RedPajamaGithub


British Steel has released a stunning new cinematic film, giving a never-before-seen insight into its exhilarating manufacturing operations (scroll to the bottom of this page to view the film).
Paul Martin, British Steel Deputy CEO, said: "We wanted to share what an awe-inspiring business and industry we're in and this film captures the pride, passion and performance at the heart of British Steel.
With annual steel production of around 3 million tonnes, British Steel's business is complex. It can transform raw materials into nearly 1,500 different grades of steel and specialises in rail, wire rod, constructional steel and special profiles.
The film was shot at British Steel's Scunthorpe steelworks and at its Teesside operations including Teesside Beam Mill and Special Profiles Mill in Skinningrove.


text:
Do the Giants have anything to play for in Week 18?
Will the Giants play their starters in Week 18?
By Chet Gresham@ChetGresham Jan 1, 2023, 2:16pm PST
Share All sharing options for: Do the Giants have anything to play for in Week 18?
Photo by Jamie Squire/Getty Images
The New York Giants beat the Indianapolis Colts 38-10 in Week 18. That easy win locked them into a wild card playoff spot. So far, the NFC East has the Eagles, Cowboys and Giants locked into the playoffs, while the Washington Commanders still have some slim hopes after losing to the Browns.
The Giants will finish the season with a winning record no matter what they do in Week 18, as they are currently at 9-6-1. This will be their first winning record since 2016 when they went 11-5 and lost in the Wild Card round.
Can the Giants move up or down in the playoff seeding?
Right now New York sits as the sixth seed in the NFC and cannot move out of the sixth spot with a win or loss against the Eagles next week. They have nothing to play for and could sit their starters in the final game as they prepare for the playoffs.


text:
Zinaida Greceanîi (født 7. februar 1956) er en moldovisk politiker, der var Moldovas premierminister fra 31. marts 2008 til 14. september 2009.

Moldovas premierministre
Politikere fra Moldova
Kvindelige regeringschefer

redpajama_set_name: RedPajamaWikipedia


Progress Rail, the parent of Electro-Motive Canada (EMC) in London, Ont. announced on Feb. 3 that it is closing the plant.
The roughly 450 unionized employees of EMC were locked out on Jan. 1. They are represented by Local 27 of the Canadian Auto Workers (CAW).
CAW president Ken Lewenza responded that the action "doesn't come as a total surprise."
"Caterpillar had no intention of keeping this plant open. From day one, we believed that Caterpillar was trying to provoke a crisis, by forcing deep cuts that were not possible."


This Afternoon... Showers likely, mainly before 5pm. The rain could be heavy at times. Cloudy, with a high near 61. South wind around 7 mph. Chance of precipitation is 60%. New precipitation amounts of less than a tenth of an inch possible.
Tonight... A 30 percent chance of showers, mainly before 7pm. Mostly cloudy, with a low around 54. South wind 9 to 14 mph. New precipitation amounts of less than a tenth of an inch possible.
Sunday... A 20 percent chance of showers after 2pm. Partly sunny, with a high near 69. South wind 8 to 10 mph.
Sunday Night... Mostly cloudy, with a low around 49. South wind around 5 mph becoming calm in the evening.
Monday... A 40 percent chance of showers after 10am. Partly sunny, with a high near 65. North wind 5 to 9 mph. New precipitation amounts of less than a tenth of an inch possible.
Monday Night... A 30 percent chance of showers before 2am. Mostly cloudy, with a low around 46. North wind around 7 mph. New precipitation amounts of less than a tenth of an inch possible.
Tuesday... A 30 percent chance of showers after 2pm. Mostly cloudy, with a high near 62. Light and variable wind.
Tuesday Night... Showers likely, mainly after 8pm. Mostly cloudy, with a low around 44. South wind around 7 mph. Chance of precipitation is 60%.
Wednesday... A 30 percent chance of showers. Mostly cloudy, with a high near 55. Calm wind becoming north 5 to 8 mph in the morning.
Wednesday Night... A 30 percent chance of showers after 2am. Mostly cloudy, with a low around 39. Northeast wind around 6 mph becoming east after midnight.
Thursday... A 30 percent chance of showers. Partly sunny, with a high near 55. South wind around 5 mph.
Thursday Night... A 30 percent chance of showers. Mostly cloudy, with a low around 41. South wind around 6 mph.
Friday... A 40 percent chance of showers. Mostly cloudy, with a high near 57. South wind around 6 mph.
Friday Night... Mostly cloudy, with a low around 39. Calm wind becoming northwest 5 to 8 mph after midnight.
Saturday... Mostly sunny, with a high near 55. North wind around 10 mph, with gusts as high as 21 mph.


text:
using System;
using System.Collections.Generic;
using System.Linq;
using System.Reflection;
using System.Reflection.Emit;
using System.Text;
using System.Threading;

namespace DapperExtensions.SqlMapper.Proxy
{
    public class ProxyGenerator
    {
        private static readonly Dictionary<Type, object> TypeCache = new Dictionary<Type, object>();

        public static T GetClassProxy<T>()
        {
            // A class proxy could be implemented if all properties are virtual
            // otherwise there is a pretty dangerous case where internal actions will not update dirty tracking
            throw new NotImplementedException();
        }

        public static T GetInterfaceProxy<T>()
        {
            Type typeOfT = typeof(T);

            object k;
            if (TypeCache.TryGetValue(typeOfT, out k)) return (T)k;

            var assemblyBuilder = GetAsmBuilder(typeOfT.Name);
            var moduleBuilder = assemblyBuilder.DefineDynamicModule("SqlMapperExtensions." + typeOfT.Name); // NOTE: to save, add "asdasd.dll" parameter

            var interfaceType = typeof(IProxy);
            var typeBuilder = moduleBuilder.DefineType(typeOfT.Name + "_" + Guid.NewGuid(), TypeAttributes.Public | TypeAttributes.Class);
            typeBuilder.AddInterfaceImplementation(typeOfT);
            typeBuilder.AddInterfaceImplementation(interfaceType);

            //create our _isDirty field, which implements IProxy
            var setIsDirtyMethod = CreateIsDirtyProperty(typeBuilder);

            // Generate a field for each property, which implements the T
            foreach (var property in typeof(T).GetProperties())
            {
                var isId = property.GetCustomAttributes(true).Any(a => a is Attributes.KeyAttribute);
                CreateProperty<T>(typeBuilder, property.Name, property.PropertyType, setIsDirtyMethod, isId);
            }

            var generatedType = typeBuilder.CreateType();

            //assemblyBuilder.Save(name + ".dll");  // NOTE: to save, uncomment

            var generatedObject = Activator.CreateInstance(generatedType);

            TypeCache.Add(typeOfT, generatedObject);
            return (T)generatedObject;
        }

        private static MethodInfo CreateIsDirtyProperty(TypeBuilder typeBuilder)
        {
            var propType = typeof(bool);
            var field = typeBuilder.DefineField("_" + "IsDirty", propType, FieldAttributes.Private);
            var property = typeBuilder.DefineProperty("IsDirty",
                                           System.Reflection.PropertyAttributes.None,
                                           propType,
                                           new Type[] { propType });

            const MethodAttributes getSetAttr = MethodAttributes.Public | MethodAttributes.NewSlot | MethodAttributes.SpecialName |
                                                MethodAttributes.Final | MethodAttributes.Virtual | MethodAttributes.HideBySig;

            // Define the "get" and "set" accessor methods
            var currGetPropMthdBldr = typeBuilder.DefineMethod("get_" + "IsDirty",
                                         getSetAttr,
                                         propType,
                                         Type.EmptyTypes);
            var currGetIL = currGetPropMthdBldr.GetILGenerator();
            currGetIL.Emit(OpCodes.Ldarg_0);
            currGetIL.Emit(OpCodes.Ldfld, field);
            currGetIL.Emit(OpCodes.Ret);
            var currSetPropMthdBldr = typeBuilder.DefineMethod("set_" + "IsDirty",
                                         getSetAttr,
                                         null,
                                         new Type[] { propType });
            var currSetIL = currSetPropMthdBldr.GetILGenerator();
            currSetIL.Emit(OpCodes.Ldarg_0);
            currSetIL.Emit(OpCodes.Ldarg_1);
            currSetIL.Emit(OpCodes.Stfld, field);
            currSetIL.Emit(OpCodes.Ret);

            property.SetGetMethod(currGetPropMthdBldr);
            property.SetSetMethod(currSetPropMthdBldr);
            var getMethod = typeof(IProxy).GetMethod("get_" + "IsDirty");
            var setMethod = typeof(IProxy).GetMethod("set_" + "IsDirty");
            typeBuilder.DefineMethodOverride(currGetPropMthdBldr, getMethod);
            typeBuilder.DefineMethodOverride(currSetPropMthdBldr, setMethod);

            return currSetPropMthdBldr;
        }

        private static void CreateProperty<T>(TypeBuilder typeBuilder, string propertyName, Type propType, MethodInfo setIsDirtyMethod, bool isIdentity)
        {
            //Define the field and the property
            var field = typeBuilder.DefineField("_" + propertyName, propType, FieldAttributes.Private);
            var property = typeBuilder.DefineProperty(propertyName,
                                           PropertyAttributes.None,
                                           propType,
                                           new Type[] { propType });

            const MethodAttributes getSetAttr = MethodAttributes.Public | MethodAttributes.Virtual |
                                                MethodAttributes.HideBySig;

            // Define the "get" and "set" accessor methods
            var currGetPropMthdBldr = typeBuilder.DefineMethod("get_" + propertyName,
                                         getSetAttr,
                                         propType,
                                         Type.EmptyTypes);

            var currGetIL = currGetPropMthdBldr.GetILGenerator();
            currGetIL.Emit(OpCodes.Ldarg_0);
            currGetIL.Emit(OpCodes.Ldfld, field);
            currGetIL.Emit(OpCodes.Ret);

            var currSetPropMthdBldr = typeBuilder.DefineMethod("set_" + propertyName,
                                         getSetAttr,
                                         null,
                                         new Type[] { propType });

            //store value in private field and set the isdirty flag
            var currSetIL = currSetPropMthdBldr.GetILGenerator();
            currSetIL.Emit(OpCodes.Ldarg_0);
            currSetIL.Emit(OpCodes.Ldarg_1);
            currSetIL.Emit(OpCodes.Stfld, field);
            currSetIL.Emit(OpCodes.Ldarg_0);
            currSetIL.Emit(OpCodes.Ldc_I4_1);
            currSetIL.Emit(OpCodes.Call, setIsDirtyMethod);
            currSetIL.Emit(OpCodes.Ret);

            //TODO: Should copy all attributes defined by the interface?
            if (isIdentity)
            {
                var keyAttribute = typeof(Attributes.KeyAttribute);
                var myConstructorInfo = keyAttribute.GetConstructor(new Type[] { });
                var attributeBuilder = new CustomAttributeBuilder(myConstructorInfo, new object[] { });
                property.SetCustomAttribute(attributeBuilder);
            }

            property.SetGetMethod(currGetPropMthdBldr);
            property.SetSetMethod(currSetPropMthdBldr);
            var getMethod = typeof(T).GetMethod("get_" + propertyName);
            var setMethod = typeof(T).GetMethod("set_" + propertyName);
            typeBuilder.DefineMethodOverride(currGetPropMthdBldr, getMethod);
            typeBuilder.DefineMethodOverride(currSetPropMthdBldr, setMethod);
        }

        private static AssemblyBuilder GetAsmBuilder(string name)
        {
            var assemblyBuilder = Thread.GetDomain().DefineDynamicAssembly(new AssemblyName { Name = name }, AssemblyBuilderAccess.Run); // NOTE: to save, use RunAndSave
            return assemblyBuilder;
        }
    }
}


Everline, Wonga's specialist operation for small businesses, has appointed Octopus Group to improve brand awareness.
Octopus won the work following a competitive pitch involving two other agencies. It has been briefed to create an integrated communications programme to increase brand awareness and drive customer acquisition.
Everline is a short-term digital lender for small and medium enterprises, offering loans to entrepreneurs. It launched as Wonga for Business in May 2012 and rebranded as Everline last year, while Wonga was seeking to respond to criticism that it was exploiting vulnerable customers.
Octopus will work on brand awareness including maximising strategic partnerships, web development, digital engagement and PR.
The agency will report to Everline head of marketing Anthony Harrison, who said that marketing and PR would play a vital role in driving the company's growth and developing channels with strategic partners.


Bill is on vacation. Executive Producer Peter Ogburn and Democratic Strategist Eric Burns fill in today.
Bill on the road: Catch Bill with Ithaca's 1470 WNYY on September 24th with Randi Rhodes and Alan Colmes at the Hangar Theatre!
Bill is on Facebook. Become a fan of his new page here!


The business meeting commences at 13:45 with the Gospel Standard Society AGM, followed by Bethesda's AGM after the middle hymn.
1. Chairman to open the meeting.
2. To consider and approve the minutes of the AGM held on 13 April 2018. These can be found here.
3. General Manager to introduce the Annual Report and Financial Statements for the year ended 31 December 2018.
4. To approve and adopt the Annual Report and Financial Statements for the year ended 31 December 2018, which can be found here.
5. General Manager to announce the result of the ballot for election of members of the Bethesda Fund Committee.


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SubTopic Java platforms
TSS Java Symposium 2006 Podcasts Collection
TSS has assembled a collection of podcast recordings from some popular technical sessions and panels presented at TSSJS 2006. Below you will find a collection of links to download the presentations in their entirety, including slides.
Server Side Contributors
Podcast: 2010 - A Developer's Odyssey
In the "real world," deployments rarely fit the boxes developers would like to put them in. It's hard to find deployments that are fully spec-compliant to Java EE or .NET. Instead, you find C, C++, Perl, Ruby and AWK all working together to create an environment that works. However, developers prefer homogenous, clean environments, even though they don't actually exist.
In this podcast, taken from a panel at TSSJS-Europe, Bruce Tate, Wayne Beaton, Erik Dornenburg and Ted Neward discuss how developers, if they could start over, would design the ideal development environment.
Suppose you took a look into a crystal ball and tried to come up with the way things were meant to be done in the future - choosing how IDEs would work, how implementations would interact, and what languages would be used for what purposes. What would you include in your development environment?
Listen to Podcast | Discuss
Podcast: Geronimo Panel Discussion
Why J2EE developers should care about Geronimo
Geronimo's plugin framework
Creating a custom assembly of Geronimo
Software as a product vs. software as a service
Support for OSGi
Synergy between Geronimo's XBean and OSGi
How Geronimo is addressing inhibiting factors for open source in commercial environments
Differences and conflicts between WebSphere and Geronimo
Desired features for Java 6 from a Geronimo perspective
In this podcast, taken from the Geronimo Panel Discussion held at TSSJS Barcelona, panelists including Bruce Snyder, Aaron Mulder and James Strachan answer questions about usage and structure of the growingly popular J2EE application server hosted by Apache. Geronimo's future development is also discussed. Topics include: What do you think the future holds for Geronimo? What features would you like to see beyond what's offered in 1.1.1?
Podcast: Heinz Kabutz on Productive Coding
Listen to Podcast | Slides | Discuss
Modern IDEs have revolutionized the way in which we are able to churn out code. In this podcast, taken from a session at TSSJS-Europe, Dr. Heinz Kabutz, publisher of "The Java Specialists" newsletter, demonstrates practical tips for coding Java "at the speed of light." According to Kabutz, most programmers are held back by bad habits and never fully utilize the power that is at their fingertips. To remedy this, Kabutz offers his tips on developing keyboard skills, writing useful comments, and refactoring quickly and correctly. Also covered are keywords such as "final" (not so final anymore in Java 5) and tools to help detect dead or duplicate code. What other tips can you offer for more productive coding?
Podcast: Advanced Ajax Applications with DWR
How to integrate DWR into your existing web applications, whatever your current codebase looks like
How to avoid the common mistakes people make when writing a first Ajax application, and how to debug problems using the best available tools
Several tricks you can use to make your website more responsive and easier to use along with looking at the available libraries to reduce the amount of code you need to write
In this podcast, taken from Joe Walker's presentation on Ajax and Direct Web Remoting (DWR) at TSSJS Barcelona, the DWR author gives inside tips on using the Java open source library and leads a discussion on developing and using DWR and Ajax. Topics include: Joe starts with DWR's own utility library and indicates some of the other tools that work well with DWR. Joe also spends some time looking at DWR's current features and where new features are being developed.
Podcast: Mike Keith on Java Persistence
Key aspects of Java persistence, including use of the EntityManager API
Persistence units and persistence contexts
Object-relational mapping using Java metadata annotations
Extensions to EJB QL
How to use Java persistence in Java SE environments
One of the key results of the work on EJB 3.0 has been the introduction of a new, standard API for Java persistence and object-relational mapping (ORM). This work initially began as part of EJB 3.0 and, in response to the urging of the Java community, has been expanded to include use in Java SE environments ("outside the Java EE container"). In this podcast, taken from a presentation at TSSJS-Europe, Mike Keith, Oracle TopLink Architect, EJB 3.0 co-spec lead and Java EE 5 expert group (JSR 244) member, discusses everything Java persistence. The session covers:
Podcast: Advanced Agile Techniques - Beyond XP
Many development teams have adopted some, if not all, of the techniques of Extreme Programming (XP). There is far more to agile software development, however, than XP. In this presentation, given at TheServerSide Java Symposium 2006 in Las Vegas, Scott Ambler discusses advanced agile techniques such as initial architectural modeling, database refactoring, model storming and agile documentation practices.
Podcast: Up Close & Personal with Tim Berners-Lee
Listed by Time magazine as one of the 100 greatest minds of this century and Originator of the Web and director of the World Wide Web Consortium talks about how far we've come, and about the challenges and opportunities ahead. His inspiring work on the Web set the stage for a world of changes in the way people do business, entertain themselves, exchange ideas, and socialize.
Podcast: Patrick Linskey on the EJB3 Java Persistence API
The EJB3 Java Persistence API (JPA) is the successor to the oft-lambasted EJB2 container-managed persistence entity bean model. How well does it meet its goals? Is it getting a better reception than its predecessors? In this podcast, taken from a presentation at TSSJS-Europe, EJB team lead at BEA, member of the EJB expert group and standards-based persistence evangelist Patrick Linskey discusses his thoughts about the best and worst of the JPA. Linskey categorizes both key and missing features as good, bad, or just plain ugly. Linskey also gives his predictions about upcoming best practices and antipatterns. What successes or shortcomings do you find in the EJB3 Java Persistence API?
Podcast: Up Close and Personal with the JCP
At TheServerSide.com's recent Java Symposium in Barcelona, panel members discussed the JCP's strengths and weaknesses; more transparency and better communication among JSRs were some recommendations for improvement.
Podcast: John Davies on the Investment Banking Technology Stack
In this podcast, taken from a keynote presentation given at TSSJS-Europe, C24 co-founder and CTO John Davies discusses the technology stack used by investment banks. In his presentation, Davies positions various technologies as used by some of the world's largest financial institutions. The presentation covers what banks like or don't like and why, what they use, what they'd rather not use, and what they're looking at for the future. Technologies covered include POJOs, JSE 5 and 6, JEE, Spring, Linux, JavaSpaces, messaging, caching, databases, and Web services. What technologies do you think are best suited for investment banking?
Podcast: Simon Phipps on Java and Open Source
What matters to us, in the world of open source software development, is not so much the license - yes, that's very important, and the shift towards pre-approved licensing is a key shift, but what matters to us is, assuming we're able to demonstrate adequate skill, are we able to get commit privileges, are we able to influence the direction of the community, and most importantly, do we have the tools with which we are able to make business commitments to our customers. Those are the really important questions if you're looking at an open source community.
While many people equate "open source" with "Linux" or "free," the truth is much more far-reaching than short-term cost savings or a challenge to incumbent vendors. In this podcast, taken from his keynote presentation titled "The Zen of Free: Models for Understanding Open Source Software" at TSSJS-Europe, Simon Phipps, Chief Open Source Officer at Sun, discusses the evolution and benefits of open source. In particular, Phipps covers the model behind open source, and how the social context in which it is appearing changes the development, delivery and pricing of software. Phipps also describes his idea of the best open source-based products, and different delivery and product models that are likely to emerge. Based on your experiences, what open source product models are most successful? In what areas do you see open source affecting software the most?
Dig Deeper on Java EE development and enterprise Java platforms
Containers and the cloud push middleware technology forward
Here's how to add Java certified developer to your resume
Fearless enhancement of legacy Java code with new SE features
Oracle VP talks Java EE 8, Java platform update at JavaOne
Java SE 9, OpenJDK energize Java community at JavaOne 2017
From reactive design to JUnit 5, here's what's hot at JavaOne 2017
How deep learning and AI techniques accelerate domain-driven design
Java string
Java platform: Invigorating robustness and simplicity
Java evolution into a functional programming language reflects demand
Static code analysis with Klocwork
Is your data persistence problem really a problem with the network?
TheServerSide Symposium June 2004 Coverage – TheServerSide.com
Apache hands Geronimo compliance weapons – ComputerWeekly.com
TSS Java Symposium conference coverage 2005 – TheServerSide.com


Dune Shoes Sale Women Natural 'Guest' slipper cut toecap espadrille shoes Dune London s handsome Guest espadrille shoe is an easy everyday style. Showcasing a mini wedge cleated sole with raffia and toecap detail. A pull up tab and slipper cut silhouette complete the design.


This page showcases the various subjects that are covered here at the City of Bullard. We will be posting how-to videos throughout the year to help our citizens and community with efficiency in utilizing our services. For ideas or suggestions on subjects to create a video on, please reach out to Letti Goodrich, our Director of Public Relations & Communications. We are always happy to receive input and ideas from our community!


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Q: Settings to connect a OneLogin PHP SAML Toolkit demo app to an ADFS Identity Provider I have successfully set up the demo test for the OneLogin PHP SAML Toolkit (https://packagist.org/packages/onelogin/php-saml) connecting to a SAML IdP on onelogin.com following the excellent tutorial here: https://developers.onelogin.com/saml/php
Now I am attempting to repoint the demo test to a functioning ADFS IdP we have set up.
Although I understand it is supported, there is no documentation on how to configure the settings.php file.  The SAML 2.0 endpoint URL naming conventions do not seem to map well to ADFS endpoint names or descriptions.
I'm new at SAML and ADFS implementations and would kindly appreciate a pointer to documentation, or ideally, an example settings.php file for a OneLogin PHP SAML Toolkit demo app that points to an ADFS implementation.

redpajama_set_name: RedPajamaStackExchange


There is no doubt that the European masters Michelangelo, Donatello, and Bernini all influenced Zarco Guerrero. In fact, they inspired him to also recognize the art of his indigenous roots.
Bob Haozous, Preston Singletary, and Roxanne Swentzell are luminaries in the world of Native American sculpture. Critics, artists, and tribal people alike hold them in high regard, but their gateways to artistic expression represent a wide expanse of diverse cultures and genres.
Allan Houser (1914-1994) is one of the most important twentieth-century sculptors to have emerged in the United States.
"Carving Katsina dolls wasn't regarded as making art when I was learning to do it," says D'Armon Kootswatewa, whose Early Morning Singer (Talavai) Katsina doll is one of the many high-value, wood sculptures that he makes as art objects intended to share aspects of Hopi worldview with others. Like other successful contemporary Hopi Katsina doll carvers, Kootswatewa feels the pull of two worlds, Hopi and American, the latter often referred to as "Anglo" in the Southwest.


You should get into wealth management roles. This is basically a sales profile in which you sell financial products like mutual funds, insurance, debt, equity etc. For such roles you should target financial services companies like commercial banks, NBFCs etc. Apart from that do enroll yourself in CFP (Certified Financial Planner) certification that you can do with your job.


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console.log(null == 0);
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Nigerian pop sensation Davido is the second guest on Ndani TVs "The Juice" for Season 2.
The HKN Music act sat with Toolz and gave us a glimpse into his rise to success, the highs and lows in his journey through super stardom, the viral response to his hit single "Skelewu", "Aye", cars, fashion and of course the ladies.
Enjoy this exclusive inside look into the life of one of Nigerias biggest superstars.


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Posted on February 29, 2016 February 29, 2016 by jona
The latest Humble Book Bundle is a massive stack of Pathfinder stuff, for damn cheap! So this seems like as good a time as any to talk about Pathfinder, and how I feel about it.
A Short History Lesson
Back in the dim and distant past, there was D&D. Then there was AD&D, then 2nd edition, and then 3rd edition, which was then 'patched' to 3.5. Pathfinder was released at about the same time as 4th edition (2009), and while 4th edition was totally new (and horrible), Pathfinder was intended to be an extension and rework of 3.5. So all the people that would have moved on to 4th ed didn't (because – as I said – horrible), and started playing Pathfinder instead.
So Pathfinder has been around for 6-7 years, and is ridiculously popular. It's got more content than for just about any RPG ever. But that also means it's based on a rules system that's now 15 years old, and from a time when D&D wasn't cool like it is now, but played exclusively by nerds with terrible hygiene.
If you've ever played D&D, Pathfinder is almost second nature. Your character has the usual stats like strength, dexterity, and so on; you choose a class like fighter, wizard, or rogue; and actions are resolved by rolling a d20 and adding some numbers, to see if you beat the number you needed to. No problem.
My issue is that the role-playing is almost drowned under the weight of rules, character options, and other shenanigans.
Rule Density
Some RPGs like to be rules-light, and rely on the GM and players 'winging it' and making up something that sounds fun and fair. Pathfinder likes to give you rules for everything.
Let's look at the stats for a typical enemy – an ogre. See how under defence it has 3 armour classes? That's because some abilities rely on actually hitting an enemy (i.e. penetrating armour), while others just have to 'touch' them. Plus you might catch an enemy unaware, and so then they would then be 'flat-footed'.
All creatures also have 3 saves: Fortitude, Will and Reflex. Which makes sense, some tings you tough out, some you dodge and some you mentally resist. But all creatures also have a Combat Manoeuvre Defence (CMD) which indicates how difficult they are to disarm, trip, shove, grapple, etc.
Speaking of combat manoeuvres, there are separate rules for each of them. And a character might be really good at say tripping opponents, but fairly useless at shoving them, depending on what feats and abilities they have (I'll come to them later).
Make a Character
Pathfinder likes to give you a lot of options when you're making a character and levelling up. Which is good, but there's a LOT of options, and not all of them are equal.
Let's say you're making a new character. Keeping things simple, you're going to be a human fighter, and so you get to pick two feats! Let's look a the feat list…
Oh. That's a lot of choice. Also notice how some feats have prerequisites that are other feats? So before you can be good at grappling, you need to take the unarmed strike feat. But in order to shove well, you need the power attack feat. In order to just grab someone and shove them, you need to be like a 4th level fighter.
That's just one choice. If you're a rogue, at level 2 you choose a rogue talent. It's a neat idea, but one of your options is to leave an enemy bleeding after an attack, while another is…to crawl faster than normal. And that's my main problem with all this 'choice'. Some choices are inherently better than others, to the extent that it feels like a trap.
Newer is Always Better
New content is always being created for Pathfinder. The problem is that it doesn't all work properly, or inline with the old stuff.
Some things just overpower the old, meaning that a campaign with the core rules is very different to one that uses all the extras. The ninja for example, can do everything a rogue can, but a little bit better. That doesn't really matter if everyone is aware of it, but it feels like a way of ensuring everyone buys the new stuff. Plus it opens up the possibility of some weird game-breaking munchkin behaviour.
There's also a lot of 'meddling' with newer books, where the makers seem to want to create lots of new stuff, even when no-one wants it. One of the later books introduces the 'roof-runner' archetype for the rogue. This gives you a feature:
"At 2nd level, a roof runner can use her acrobatics skill to attempt a rapid descent from a rooftop or another surface, ricocheting against another surface and then diving through an opening (such as a balcony or window) directly below. So long as she has at least two surfaces no farther than 10 feet apart to bounce against, she can ricochet her body back from one to the next, descending great distances with a single check."
Why is that not just a thing that any character can do? If I was a GM and a character had a high acrobatics score, and they described the above, I'd let them try it. But now it's been written into a specific class feature, no other character can attempt it?
Should You Play It?
All of that was very negative! I don't hate Pathfinder at all, I actually really like it. There's just a lot of stuff, and loads of stupid fiddly rules, so that I'd never consider GM'ing it. Luckily I've know someone that does (and does well), so I can enjoy it as a player.
Deciding if any game is 'good' or 'bad' is basically impossible, they all fit into their own niches, and appeal to different people. But I think it's fair to compare Pathfinder to 5e D&D, as they cover a lot of the same ground:
Pathfinder has more stuff. Do you want to play a mermaid paladin who smites enemies with her double katana? You probably can.
Pathfinder has far more character options, so is great if you like spending hours poring over books, building your perfect character. It makes it fairly terrible if you don't like this sort of 'munchkin' behaviour.
The rules in Pathfinder are more detailed, and cover more possibilities. Great if you like long, tactical battles, but almost impossible to run without miniatures and a map.
In short: Pathfinder is great if you're a massive nerd. But in my opinion, 5e is better is most ways.
I look forward to the comments on this one!
Posted in General Nonsense, ReviewsTagged D&D, Pathfinder
2 thoughts on "Pathfinder"
Gabe says:
Great article and sums up my experience of PF very well. What I'm coming to realise is that you need to use the rules as a framework to help you run a game. The rules are a guideline and as a GM you need to be free to totally ignore them, the game is king not the rules. Rules lawyers beware.
Pingback: I May Have Been Wrong About Pathfinder – the murder nerds


Vision's Soccer Skills Camp is going international! All new for 2018, our Soccer Skills Camp will give participants the opportunity to spend an entire week working on developing footskills and 1v1 moves made famous by the top players from Europe and South America.
During our South America camp players learn the moves and tricks used by the likes of Messi, Maradona, Neymar, Pele and many more players from Brazil, Argentina, Uruguay and other countries in South America. While participants attending our European camp will have the opportunities to develop the skills and footwork made famous by players such as Ronaldo, Rooney, Cruyff, and Matthews from all of the top soccer nations in Europe. All skills are taught in a fun and engaging environment using our progressive training curriculum which helps players develop confidence and creativity when in possession of the ball.
Players will leave each camp being more confident on the ball and with a whole host of skills and moves they can rely on to be successful in games.
Activity 1 - Morning Scrimmages.
Activity 2 - Footwork and footskill exercises.
Activity 3 - Introduction of daily skills - No pressure environment.
Activity 5 - Performing daily skills in a full pressure game situation.
Activity 6 - Daily tournament.
Please check back at a later date for 2019 camps. Our summer camp dates will be posted by April 1st. Thank you!


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FeaturedNewsNIMechE
HomeNewsFoundation honours Engineer, Dr. Olufemi Lalude who rejected $6m bribe
Foundation honours Engineer, Dr. Olufemi Lalude who rejected $6m bribe
The the Akinjide Adeosun Foundation (AAF) has conferred its 2020 Leadership Award on the first Managing Director of Shell Nigeria Exploration and Production Company (SNEPCO), Dr Olufemi Lalude, according to report monitored by NAN.
This comes decades after Lalude, who is the second National Chairman of Nigerian Institution of Mechanical Engineers, NIMechE, rejected a 6 million dollar bribe offer, the foundation said in a statement on Wednesday in Lagos.
The award, "Leadership in Integrity'' was conferred on Lalude, now 81, during the AAF 5th annual colloquium with the theme: "Integrity – A Sine Qua Non to Building a Prosperous Nation''.
Speaking at the event which held virtually, Mr Akinjide Adeosun, AAF's Founder and Chief Executive Officer of St. Rachael's Pharmaceutical Nigeria Ltd., said the recognition of Lalude was is in line with the core mandate of the foundation.
The core mandate is based on the belief that life would be good for everyone if the nation gets leadership right in all spheres.
"Integrity is an essential building block to building a prosperous nation. Truthfulness, honesty, respect for people, hard work and humility are traits of Integrity.
"Many years ago, our awardee, Papa Olufemi Lalude, the first managing director of the Shell Nigeria Exploration & production Company SNEPCO was offered a bribe of 6 million dollars.
"The organisation that offered him the bribe moved against him. However, he refused to be cowed and stood his ground.
"He was sued with his employer but he triumphed. Lalude is a man of integrity, a rarity in our clime dwarfed by corruption and greed.
"Today, Papa at 81 is living a peaceful, joyous and fulfilled contented life.''
He adds: "We are celebrating him today. He began his career with integrity as his legacy in mind.
" We have many good people in Nigeria. We must celebrate them to dwarf the bad publicity the few bad people is giving our nation."
In his presentation, Gov. Seyi Makinde of Oyo State said that Nigeria would continue to find it difficult to grow without putting structures in place to strengthen openness, truthfulness and transparency in leadership.
According to him, the absence of a structure for checks and balances is likely to continue to stunt the growth of the country.
"There is a large trust gap between the citizens and leaders of this country due to lack of transparency on the part of the political class.
"When we talk about integrity in governance, it entails honesty, transparency and accountability in governance.
"Integrity is tied to prosperity of any nation in so many ways and as a leader, you have to be very honest," he said.
The foundation called on leaders in government to drive patriotism and prosperity by upholding trust and demonstrating transparency.
Speakers at the event unanimously said that the nation had lost its old value system by embracing dishonorable practices and lack of accountability in all spheres across the family, school, business, government and society levels.
A communiqué was also issued which stressed that integrity and honesty remain the collective responsibility to save Nigeria.
Engineer Dr. Olufemi A. Lalude attended the Ibadan Grammar School (1952-1958) before proceeding to the University of Minnesota in the United States where he obtained B.Sc. (1962) and M.Sc. (1963) Mechanical Engineering. He subsequently proceeded to the University of California where he earned a Ph. D. in Engineering in 1969.
Between 1964 and 1969, Engineer Lalude worked as junior and later as Research Engineer at the College of Engineering, University of California, Los Angeles.
He also worked as part of a team that developed medium sized factories for the manufacture of ceramics, paper and electronic radios as part of the regional development plan for North-East Brazil.
Thereafter, he joined Bechtel Corporation in September, 1969 as a Senior Engineer on a design team working on a novel sodium-cooled fast breeder nuclear power plant planned for North-East Pennsylvania, United States.
Following his decision to return to Nigeria, he joined The Shell Petroleum Development Company of Nigeria in December, 1970 where he worked in various capacities and rose to become the first Nigerian to occupy the positions of Chief Engineer for the Eastern Division (1980 to 1982) and the Engineering Manager for the entire company from 1984 to 1989.
After a stint as General Manager of Shell's Western Division(1989 to 1992) he was appointed as the first Managing Director of Shell Nigeria Exploration and Production Company (SNEPCO) which is now a major operating company in deep water offshore, and served until he retired in December 1996.
Since January 1997, he has co-founded with others Petrodata Management Services Ltd. (Currently serving as a Director) and Crestech (formerly Crestville) Engineering Ltd. (Serving as Chairman), served as a Director of Addax Petroleum Company and engaged in part-time engineering consultancy with Elkgrove Ventures Ltd.
Engr. Lalude is a Fellow of the Nigerian Society of Engineers, a past Chairman of the Mechanical Division of the Nigerian Society of Engineers, (1994-1996). Honorary Member of the Nigerian Association of Petroleum Explorationists, and a Member of the American Society of Mechanical Engineers, and has published several articles in learned journals.
He is a foundation Fellow of the Nigerian Academy of Engineering and was honoured with the Pathfinder Award for meritorious contributions to the development of the Nigerian Oil Industry.
Akinjide Adeosun Foundation
Inspire Engineers
NIMechE
Olufemi Lalude
Seyi Makinde
Houston Branch of Nigerian Society of Engineers Elects Jebutu as New Chairman
Vacancies for Scaffolders at 17 Asus Resources Limited – 4 Openings
Lanre September 10, 2020 At 9:41 am
Wonderful news. We need to hear more of this type of news to let our youths know that not all adult Nigerians are bribe takers, and that there is dignity in integrity and honesty. It pays to be contented. The reward will come, sooner or later. Congratulations to Pa Lalude.
A O KAY-DAWODU. September 10, 2020 At 12:53 pm
BABA ENGNR. LALUDE WAS HONOURED 24 YEARS AFTER!
BETTER LATE THAN NEVER.
HEARTY CONGRATULATIONS.
Mechanical Engineers institution task artisans on standard practice; set to empower Young Engineers
Expert calls for skill gap Closure in the industry; Praises NIMechE's Commitment to Youth Development
The Managing Director/CEO of Engineering Automation Technology (EATECH) Limited, Dr Emmanuel Okon has lamented the huge gap between...
An Engineer Turned Educationist Explores Her Episodes of Success
Cerebral, focused, and result-oriented, this humble intellectual who sits atop one of the leading educational institutions in Lagos,...
NIMechE NATIONAL CHAIRMAN BAGS KWAME NKRUMAH PAN- AFRICAN EXEMPLARY LEADERSHIP HONOR'S AWARD
On the Tuesday 8th January, 2019, the National Chairman, Nigerian Institution of Mechanical Engineers warmly received a delegation...
People fail because they fear each other': 9 life and leadership lessons from Martin Luther King Jr.
By Bernard Banks, Stephen F. Somerstein | Getty Images Martin Luther King Jr. Day is more than a day of...
Engineering study dispels myths on limits to renewables in SA
News September 18, 2017 0
A serious engineering study and report has dispelled the...
How Smuggled Petrol From Nigeria Floods Niger, Cameroon, Benin, Togo- Daily Trust
Reports April 5, 2021 0
Nigeria's refined petroleum products, especially the Premium Motor Spirit...
Welcome Address of Prof. Mohammed B. Ndaliman, NIMechE National Chairman at Launch of the NIMechE Internship and Mentorship on-line Digital Platform
Engineers in Society August 7, 2020 0
Welcome Address, Engr. Prof. Mohammed B. Ndaliman, MNSE, FNIMechE,...
CONCEPTION TO ACTUALIZATION – END OF TENURE SPEECH BY ENGR. DR. MRS FUNMILADE AKINGBAGBOHUN.
Engineers in Society September 10, 2020 1
There comes a day in our lives when we...
Vacancy: Admin Officer at Rotation and Precision Machines Limited
Vacancies January 20, 2022 0
Rotation and Precision Machines Limited is a sales and...
Medical Tribunal punishes 20 doctors; blacklists 3, suspends 12 •List of the affected doctors
The Medical and Dental Practitioners Disciplinary Tribunal has imposed...
2m employees die yearly from work-related causes — ILO, WHO
Health Safety and Environment September 30, 2021 0
Work-related diseases and injuries were responsible for the deaths...


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Summer around Your Neck
Summer around Your Neck (2001) is the shocking story of a 12-year old boy who falls in love with a woman 30 years his senior. The book is based on facts from the author's own childhood and provides a rare insight into the sexual maturing of a young boy and devastating effects on his future. The book has been translated into many languages.
Guy Goffette
Guy Goffette is a poet and a Belgian Walloon writer born on April 18th, 1947 in Jamoigne (Ardennes). He was teacher, curator, editor, printer, librarian, translator and publisher of the notebooks of poetry "Triangle" and "Apprentypographe". He went through number of countries of Europe before putting down his suitcases to Paris where he lives nowadays. He works as a reader for Gallimar Publishers where most of his workes have been edited.
He is the author of 15 books of fiction and poetry and in 1989 was awarded the Mallarme Prize. A poet, even though he writes in prose, he published about fifteen books and acquired in 2001 the Grand prix of Poem of the French Academy for his entire work.
The Gallows Bird
The Girl with the Dragon Tattoo: Book 1 of the Millennium Trilogy
In Times of Fading Light
The Viper's Glen Miracle
Psmith in the City
İstanbul Red
Ferzan Ozpetek
The Little Old Lady Who Broke All the Rules
Catharina Ingelman-Sundberg
Dear Mr. M.
Herman Koch
Red Country
Bulgarian Roses
Georgi Tenev
The Story of a New Name
Heaven Has Returned
Clara Sánchez
All flesh is grass
Clifford D. Simak
Clocks in My Mother's Room
Tanja Stupar Trifunović
The Spinning Heart
Donal Ryan
The Howling Miller
Arto Paasilinna
The Moor's Last Sigh


Here at Bottega Italiana we take personal pride in our product. Our gelato is handmade daily and in small batches using natural flavors and ingredients to ensure the highest quality. Our milk and produce are hand chosen from local markets to ensure the freshest ingredients. Fruit flavors are only made seasonally, because we can only use fruit when it is at its peak flavor and freshness. We do this to assure that we offer you the highest quality product possible.
In addition to using fresh ingredients, we at Bottega Italiana do not use any additional colors, flavors, or preservatives in our product. When it comes to flavor and color, our gelato is strictly "come as you are." Another current trend we reject is the practice of sweetening with corn syrup. You will never find corn syrup in Bottega Italiana's gelato.
For those who are lactose intolerant or vegan, Bottega Italiana also offers dairy free (and vegan) flavors. These are usually fruit flavors and are therefore seasonal. Stop in to see which dairy-free flavors we are currently featuring. In addition, our gelato was recently certified as gluten-free to meet the increasing demand of our gluten-sensitive customers.
Many ask how gelato is different from ice cream. The main difference between gelato and ice cream is that not all flavors of gelato contain dairy, but for those flavors that do, they are made with 2% milk. This results in a product that contains approximately 60% less fat and calories than American ice cream, that is made with heavy cream. In addition, the end result for those dairy free flavors is an even lower calorie count product. While still boasting a smooth velvety texture, these vegan alternatives are an excellent alternative for those that are lactose intolerant. Gelato also has much less air added to it during production, yielding a more intense and concentrated flavor.
We hope you will have the opportunity to come by soon and experience a taste of Italy for the first time. You can come sit and enjoy some of our fresh gelato at one of our caffes or even take some home to share with your friends and family.
: Made fresh daily, tiramisu is always a crowd favorite because of it's rich flavour and smooth texture. Great when mixed with any of our many flavours. Try it with a scoop of vanilla, caffe or pannacotta.
: When in season, pineapple is made fresh daily and makes for a refreshing tropical treat during the summer.
: Made fresh daily, vanilla is always a crowd favorite because of it's rich flavour and smooth texture. Great when mixed with any of our many flavours. Try it with a scoop of caffe mocha, cioccolato or nocciola.
: When in season, lemon is made fresh daily and makes for a refreshing tropical treat during the summer.
: Made fresh daily, pistacchio is always a crowd favorite because of it's rich flavour and smooth texture. You will notice our pistacchio is not a green colour, rather it is brown, marking the fact that it is made entirely without the use of artificial coloring or flavoring. Great when mixed with any of our many flavours.
: When in season, orange is made fresh daily and makes for a refreshing tropical treat during the summer.
: Made fresh daily, chocolate chip is always a crowd favorite because of its creme base and marbling of chocolate throughout.
: When in season, coconut is made fresh daily and makes for a refreshing tropical treat during the summer.
: Made fresh daily, caramel is always a crowd favorite because of its rich flavour and smooth texture.
: When in season, made fresh daily with green apples at the peak of freshness.
: Made fresh daily, coffee is always a crowd favorite, especially in Seattle, because of its rich flavour and smooth texture.
Albicocca (Apricot), Amarena (Wild Cherry), Anguria (Watermelon), Banana, Cioccoarancia (Chocolate Orange), Fichi (fig), Frutti de Bosco (Mixed Berries), Frutto della Pasione (Passion Fruit), Kiwi, Lampone (Raspberry), Lime, Mango, Melone (Cantaloupe), Mirtillo (Blueberry), Papaya and Pera (Pear) Pesca (Peach).
Chocolate, Amaretto, Belle Helene (Chocolate Pear), Caffe Mocha, Canella (Cinnamon), Cassata (Currant), Nocciola (Hazelnut), Fior de Latte (Sweet Milk), Gianduia (Chocolate Hazelnut), Latte Mou ( Dulce de Latte), Malaga (rum and raisin), Mandorla (Almond), Meringa, Noce (Walnut), Nutella, Pannacotta (Creme Brulee), Riso (Rice Pudding), Yogurt, Zabaoine (Italian Eggnog) and Zycca (Pumpkin).


text:
Dossier Climate protection
Cape Town's road to clean water
treatment-plants-cape-town
Cape Town's road to clean water
An article by: Dr. Christian Chua
Clean water for Cape Town
Modern instead of falling into disrepair
Call for new sewage treatment plants for Cape Town
Funding from KfW
80 million for Cape Town
Data protection principles
If you click on one of the following icons, your data will be sent to the corresponding social network.
Cape Town's sewage plants are overburdened. The city' s wastewater often flows unfiltered into the sea. The outdated sewage treatment plants are now being modernised. It is the first project of the European Clean Oceans Initiative.
Modernisation of treatment plants (KfW Group/Christian Chua, Thomas Schuch).
An outdoor toilet, situated in front of an approximately 20 square metres corrugated iron shack with sleeping, cooking and sitting area. It belongs to Elizabeth Rantoetse, a South African who lives in Flamingo Heights, a township in Cape Town. And Rantoetse is proud of her own toilet. As a member of the committee representing the residents of the township, she had a say in how a budget provided by the city administration for improvement measures was put to use. "We wanted and needed our own toilets," says Rantoetse. Some neighbours have also integrated their toilet into their small living spaces so that they do not have to go outside to use the toilet.
Before the 100 or so shacks in Flamingo Heights were connected to Cape Town's wastewater network six years ago, there was a block of a few pit toilets on the edge of the township for all inhabitants, which at the time numbered more than 500 people. "The sewage lead to many occurrences of disease. It smelled awful and was everywhere," recalls Elizabeth Rantoetse, who attributes the loss of her unborn child to germs in the sewage.
Support for the neighbourhood
Resident representative Elizabeth Rantoetse in front of her shack in Flamingo Heights.
Nowadays, instead of seeping into the ground or leaking out unchecked, the sewage from their dwellings ends up in one of the municipal wastewater treatment plants of which there are 26. Most of these plants were built in the fifties and sixties. They are technologically outdated and were not maintained. Of course, this makes the purification process more difficult, if it is even possible at all. In addition, the wastewater treatment plants are groaning under the strain: the capacities are designed for the Cape Town of 1990, not for a rapidly growing metropolis which now has 4.5 million inhabitants.
It is therefore inevitable that some of the wastewater continues to find its way into the ocean untreated. This wastewater, which is not treated or only inadequately treated and discharged into the sea, pollutes the coasts and beaches with faeces, cosmetics, drug and antibiotic residues, as scientists showed in a study published in 2017. Calls to expand the dilapidated wastewater treatment plants grew louder.
Read more under the image gallery.
Plants from the sixties - The Zandvliet sewage treatment plant, in the background a township. The plant is currently designed to handle 72 million litres of wastewater per day.
Expansion of the Zandvliet sewage treatment plant - The new Zandvliet sewage treatment plant will have the capacity to treat 100 million litres of wastewater per day – 28 million litres more than before.
Modernisation work - Workers in a sludge treatment plant. The old sewage treatment plants are gradually being modernised with KfW's help.
New toilets for Flamingo Heights - In the township of Flamingo Heights new sanitation facilities help improve living conditions.
Agriculture is benefiting - Once the sewage treatment plants have been modernised, the treated wastewater will also be used for agriculture around Cape Town.
Clear water - For Grenda Harris from Cape Town water is of great importance.
Plants from the sixties
The Zandvliet sewage treatment plant, in the background a township. The plant is currently designed to handle 72 million litres of wastewater per day.
Marine protection
The modernised sewage treatment plants also protect the sea at the gates of Cape Town.
This is precisely where KfW comes in. "All 26 wastewater treatment plants in the city are in need of modernisation and will be expanded and rehabilitated with our loan," says KfW project manager Carolin Brandl. KfW Development Bank is providing the city of Cape Town with EUR 80 million on behalf of the German Federal Government. "Every year around 50,000 people move to Cape Town, the expansion of the infrastructure simply doesn't keep pace," Brandl adds. One focus of the project is on increasing the energy efficiency of the plants – an important issue in a country like South Africa, which still generates almost 75 per cent of its electricity from coal. However, another priority of KfW in Cape Town is also to increase capacity: after many years of investment backlog, the infrastructure will finally be adapted to the ever-growing number of inhabitants.
The current and future capacities of the Zandvliet wastewater treatment plant in the southern part of the city clearly demonstrate this. It is currently designed to handle 72 million litres of wastewater per day. "After rehabilitation, Zandvliet will be able to process the required 100 million litres of wastewater," says Rajan Moodley, the engineer responsible for large-scale projects at the Cape Town water authority. Moodley is not worried that the capacities will soon be exhausted again. "We are already laying the foundations structurally for this plant to be able to handle as many as 150 million litres a day in the future," he says confidently. "This will be the case in thirty to forty years."
"All 26 sewage treatment plants in the city will be expanded and rehabilitated with our loan."
Carolin Brandl, KfW project manager for wastewater in South Africa
KfW provides support
KfW Development Bank promotes numerous water projects around the world.
In the medium term, the aim is also to purify the wastewater in the wastewater treatment plants. "Our water supply must become more independent of surface water," says Dr Sven Sötemann, head of planning at the water authority. Three years with little precipitation had depleted the water supply in 2018, "day zero", the day when the supply of fresh water would be switched off, was imminent. "In addition to groundwater and desalination of seawater, treated wastewater is an inexpensive and sustainable alternative. It can be used in agriculture and industry," said Sötemann, outlining future steps.
A man for tough jobs
In the Zandvliet sewage treatment plant, a worker removes the rubbish filtered out of the water, including huge amounts of plastic waste.
This drastically increases the importance of wastewater treatment plants once again. Their contribution to easing the water shortage is firmly included in plans. But before the plants can convert wastewater to usable water, the first step is to repair them. This will also address another eminently important concern: reducing marine pollution. Rarely is the link between a measure and the protection of the oceans more evident than here in Cape Town, where increasing the efficiency and capacity of wastewater treatment has a direct impact on the discharge of untreated wastewater into the sea. Enormous quantities of plastic also wind up day after day in the plant filters – meaning not in the ocean. The project is therefore also supported as part of the Clean Oceans Initiative, which KfW launched together with the European Investment Bank and the French development bank AFD. Together, the partners are providing EUR 2 billion for projects to fight pollution of the world's oceans.
The first step has been taken. Elizabeth Rantoetse is happy to see that money is now being invested in the infrastructure of the public wastewater system. She can now use her own toilet and does not have to worry about infectious diseases. What else would she like from the city administration? "Well," she says, "there's one more thing: a real house instead of a corrugated iron shack." But she is sure that this will happen too.
Published on KfW Stories: Thursday, 4 April 2019
The described project contributes to the following United Nations' Sustainable Development Goals
Goal 6: Ensure access to water and sanitation for all - There is no life without water! We need it for drinking, but also for producing food in agriculture. The United Nations thus recognised access to clean drinking water as a human right in 2008. However, 748 million people still live without clean drinking water. According to estimates, this causes the deaths of 5,000 children around the world each day. 2.5 billion people lack access to basic sanitation services.
Goal 14: Conserve and sustainably use the oceans, seas and marine resources - Protecting biodiversity, using it sustainably and fairly sharing its benefits are important factors in sustainable development. About 30 per cent of the world's fish stocks are overfished. In the European part of the Atlantic, this figure is 63 per cent; in the Mediterranean, it is already 82 per cent. Global warming and the acidification of the oceans also threaten peoples' livelihoods. Each year around ten million tonnes of plastic end up in the oceans. This does not degrade biologically, instead it disintegrates into smaller and smaller particles. Since marine animals mistake the plastic particles for food, these particles also end up in the human food chain.
Goal 6: Ensure access to water and sanitation for all
There is no life without water! We need it for drinking, but also for producing food in agriculture. The United Nations thus recognised access to clean drinking water as a human right in 2008. However, 748 million people still live without clean drinking water. According to estimates, this causes the deaths of 5,000 children around the world each day. 2.5 billion people lack access to basic sanitation services.
(4 Pictures)
All United Nations member states adopted the 2030 Agenda in 2015. At its heart is a list of 17 goals for sustainable development, known as the Sustainable Development Goals (SDGs). Our world should become a place where people are able to live in peace with each other in ways that are ecologically compatible, socially just, and economically effective.
Image-Reference
On our website, pictures taken, among others, by the following photographers/photo agencies are used:
Agentur photothek.net, Deutsche Messe Hannover, Andreas Arnold, Jörg Böthling, Dominik Butzmann, Carsten Costard, Susanne Esche, Charlie Fawell, Rendel Freude, Torsten George, Gaby Gerster, David Greedy, Peter Himsel, Barbara Högner, Frank Homann, Fred Hoogervorst, Steffen Jagenburg (BRANSCH EUROPE), Thomas Klewar, Studio Kohlmeier , Florian Kopp, Georg Lopata, Jürgen Lösel, Kirsten Milhahn, Rüdiger Nehmzow, Rolf Obertreis, Rubén Arnaldo Farina Ortiz, Holger Peters, Joachim Röttgers, Mika Schmidt, Bernhard Schurian, Jens Steingässer, Pietro Sutera, Uwe Tölle, Jan Zappner.
Fotolia.com: amandare, Yuri Arcurs, Kitch Bain, Ingo Bartussek, Sergio Donà, drizzd, Dmitry Ersler, eyewave, Zoltán Futó, Eric Gevaert, Fotolia XXV, Friedberg, goodluz, Dirk Hoffmann, imageteam, Christian Jung, Abdelhamid Kalai, Sergej Khakimullin, Vladimir Kolobov, krizz7, Kzenon, lumen-digital, marog-pixcells, Mindwalker, Miredi, mirpic, Nebuto, Tino Neitz, Christian Pedant, Franz Pfluegl, prognone, Gina Sanders, Henry Schmitt, spree berlin, SVLuma, Kheng Guan Toh, tom, Torbz, typomaniac, VRD, Joachim Wendler, Sreedhar Yedlapati.
economyinfrastructureKfW Development BankAfricaCleanOceansAgence Française de Développement EIBSDG6SDG14
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"A major task"
Overfishing, coral bleaching, plastic waste: the condition of the oceans is deteriorating dramatically. How KfW wants to protect the oceans joining forces on a European level with the Clean Oceans Initiative and through promoting the closed-loop economy.
To the article about development cooperation in Palestine
Clean water in the Gaza Strip
Gaza is an overpopulated coastal region blighted by conflicts, water shortages and poverty. KfW is promoting water supply projects and the construction of wastewater treatment plants.
To the dossier
It still sounds like utopia that we operate in such a way that no waste is generated and resources are reused again and again. In Europe, this scenario is now becoming more real. In our dossier, we present the European Joint Initiative for a Circular Economy, and projects that pursue the principle of a closed-loop economy.


text:
Rodney George "Rod" Laver (9 de agosto de 1938, Rockhampton (Queensland), Austrália) é um ex-tenista australiano que detém o recorde de títulos conquistados na carreira. Ele é o único tenista da história a ter vencido todos os 4 torneios do Grand Slam em simples  na mesma temporada em duas ocasiões distintas – primeiro como amador, em 1962, e depois como profissional, em 1969. Por tal façanha, Laver é considerado por muitos fãs de tênis o melhor tenista de todos os tempos. Em 1967 ele também ganhou Profissional Grand Slam. A quadra central do Open da Austrália é, em sua homenagem, chamada de Rod Laver Arena.

Muitos dizem que Laver não detêm o recorde de títulos de Grand Slam porque ele foi impedido de jogar entre 1963 e 1967 por ter se tornado um tenista profissional, sendo que, naquela época, os torneios do Grand Slam só podiam ser disputados por tenistas amadores e 3 dos 4 torneios eram disputados na grama. Em 1969 a proibição de tenistas profissionais disputarem Grand Slams foi retirada, o que deu início à Era Open.

Laver entrou para o International Tennis Hall of Fame em 1981.

Em 2014, Laver foi considerado pela Revista Tênis um dos "10 tenistas que transformaram a forma como o tênis é jogado". Segundo a revista, "''o maior expoente do estilo moderno de "jogador de quadra toda", ou "all-court player" como os norte-americanos chamam, o australiano canhoto não tinha falhas técnicas e era dotado de uma força desproporcional a seu tamanho". All-court player também tem o sentido do jogador ser bom em todo o tipo de quadra, seja grama, saibro ou dura.

Major finais

Grand Slam finais

Simples: 17 finais (11 títulos, 6 vices)

Duplas: 12 finais (6 títulos, 6 vices)

Duplas Mistas: 3 finais (3 títulos)

Ver também
 Rod Laver Arena

Tenistas da Austrália
Recebedores do Philippe Chatrier Award
Tenistas vencedores de torneios do Grand Slam
Membros do International Tennis Hall of Fame


I, Richard W. Norman, duly appointed, qualified, and acting Clerk to the County Board for the County of Wright, State of Minnesota, do hereby certify that I have compared the foregoing copy of a resolution, or motion with the original minutes of the proceedings of the Board of County Commissioners, Wright County, Minnesota, at their session held on the 1st day of May, 2012 on file in my office, and have found the same to be true and correct copy thereof.
Witness my hand and official seal at Buffalo, Minnesota, this 1st day of May, 2012.
BE IT RESOLVED that the County Coordinator is directed to file the redistricting plan with the County Auditor by May 2, 2012, to be effective on June 2, 2012, for the 2012 primary and general election. The County Auditor is directed to publish the redistricting plan in the Howard Lake Journal.
BE IT FINALLY RESOLVED that the districts are, for illustrative purposes, identified in a map of the county attached hereto and marked Exhibit A which by reference is hereby made a part hereof.
Published in the Herald Journal May 7, 2012.
The following Federal, State and County offices will be voted for at the State General Election to be held on Tuesday, November 6, 2012.
The filing period for these offices begins at 8:00 a.m., Tuesday, May 22, 2012 and ends at 5:00 p.m., Tuesday, June 5, 2012. Note: Filing offices will be closed Monday, May 28, 2012 in observance of Memorial Day and filing offices will be closed Wednesday, July 4, 2012 in observance of Independence Day.
The place of filing for Federal offices is the Office of the Secretary of State: State Office Building, Room 180, 100 Rev. Dr. Martin Luther King Jr. Blvd., St. Paul MN 55155-1299. The filing period for President of the United States begins at 8:00 a.m., Tuesday, May 22, 2012 and ends at 5:00 p.m., Tuesday, August 21, 2012.
The place of filing for County offices is with the Wright County Auditor/Treasurer: Wright County Government Center, 10 2nd Street NW, Room 230, Buffalo MN 55313-1195. Regular business hours are 8:00 a.m. to 4:30 p.m.
Candidates may file in person or by mail. Candidates who will be absent from the State during the filing period may arrange to file in person, prior to departure.
Published in the Herald Journal May 7, 14, and 21, 2012.
2. New masonry building with precast roof.
3. New electrical and control system.
until 11:00 AM, (Local Time) May 30, 2012 (year), and then at said office publicly opened and read aloud.
Copies of the Contract Documents may be obtained at the Issuing Office, Bolton & Menk, Inc., located at 1960 Premier Drive, Mankato, MN 56001, (507) 625-4171 upon payment of $150.00 for each set.
1. Default has occurred in the conditions of the Mortgage dated April 25, 2007, executed by Jamisen Smith, single, as Mortgagor, to Wells Fargo Financial Minnesota, Inc., as Mortgagee, and filed for record May 21, 2007, as Document No. A1053879, in the office of the County Recorder of Wright County, Minnesota. The land described in the Mortgage is not registered land.
2. The original principal amount secured by the Mortgage was $339,263.20.
6. At the date of this notice the amount due on the Mortgage, and taxes, if any, paid by the holder of the Mortgage is $348,922.61.
will be sold by the Sheriff of Wright County, Minnesota, at public auction on June 22, 2012 at 10:00 a.m. at the office of the Wright County Sheriff, 3800 Braddock Avenue NE, Buffalo, Minnesota.
8. The mortgagor must vacate the property on or before 11:59 p.m. December 24, 2012, if the mortgage is not reinstated under Minn. Stat. Sec. 580.30, the property is not redeemed under Minn. Stat. Sec. 580.23, or the redemption period is not reduced under section 582.032.
9. The time allowed by law for redemption by Mortgagor or Mortgagor's personal representatives or assigns is 6 months after the date of sale.
Published in the Herald Journal May 7, 14, 21, 28, June 4 and 11, 2012.
A strip of land 100 feet in width to be used for ingress and egress to Birch lake the centerline of which is described as follows: Commencing at the Southeast corner of Lot 2, Block 1 of Birch Heights, plat of record, thence North (assumed bearing) a distance of 265.06 feet; thence deflect right 10 degrees 20 minutes a distance of 87.2 feet; thence deflect right 73 degrees 25 minutes a distance of 12.3 feet to the Easterly line of dedicated road in said plat; thence continuing Easterly on said last described course a distance of 327.7 feet to the waters edge of Birch Lake and there terminating. The sidelines of said 100 foot strip of land are to begin on the Easterly boundary line of dedicated road.
DATE AND TIME OF SALE: June 18, 2012, 10:00 a.m.
TIME AND DATE TO VACATE PROPERTY: If the real estate is an owner occupied, single-family dwelling, unless otherwise provided by law, the date on or before which the mortgagor(s) must vacate the property, if the mortgage is not reinstated under section 580.30 or the property is not redeemed under section 580.23, is 11:59 p.m. on December 18, 2012.
LENDER: American Mortgage Network, Inc.
DATE AND TIME OF SALE: June 25, 2012, 10:00 a.m.
TIME AND DATE TO VACATE PROPERTY: If the real estate is an owner occupied, single-family dwelling, unless otherwise provided by law, the date on or before which the mortgagor(s) must vacate the property, if the mortgage is not reinstated under section 580.30 or the property is not redeemed under section 580.23, is 11:59 p.m. on December 26, 2012.
DATE AND TIME OF SALE: April 30, 2012, 10:00 a.m.
TIME AND DATE TO VACATE PROPERTY: If the real estate is an owner occupied, single-family dwelling, unless otherwise provided by law, the date on or before which the mortgagor(s) must vacate the property, if the mortgage is not reinstated under section 580.30 or the property is not redeemed under section 580.23, is 11:59 p.m. on October 30, 2012.
The above referenced sale scheduled for April 30, 2012, at 10:00 A.M., has been postponed to June 8, 2012, at 10:00 A.M., located at 3800 Braddock Avenue NE, Buffalo, MN 55313, said County and State.
If this is an owner occupied, single-family dwelling, the premises must be vacated by December 10, 2012 at 11:59 P.M.
The above referenced sale scheduled for April 30, 2012, at 10:00 A.M., has been postponed to July 25, 2012, at 10:00 A.M., located at 3800 Braddock Avenue NE, Buffalo, MN 55313, said County and State.
If this is an owner occupied, single-family dwelling, the premises must be vacated by January 25, 2013 at 11:59 P.M.
The above referenced sale scheduled for April 30, 2012, at 10:00 A.M., has been postponed to July 6, 2012, at 10:00 A.M., located at 3800 Braddock Avenue NE, Buffalo, MN 55313, said County and State.
If this is an owner occupied, single-family dwelling, the premises must be vacated by January 7, 2013 at 11:59 P.M.


text:
La Trêve (, "The Truce") é uma série de televisão de drama criminal belga (falada em francês), produzida por Anthony Rey e dirigida por Matthieu Donck.. Estreou no La Une de RTF em 21 de fevereiro de 2016, em France 2 em 29 de agosto de 2016, e na Netflix nos Estados Unidos, Reino Unido e Canadá em 21 de dezembro de 2016.

A 2ª Temporada estreou na Bélgica em 11 de novembro de 2018. Em 9 de fevereiro de 2019, foi lançada na Netflix nos Estados Unidos e em muitos outros países.

Sinopse
O detetive de polícia Yoann Peeters muda-se de Bruxelas com sua filha, Camille, para sua cidade natal, onde o corpo de um jovem jogador Africano de Futebol que foi retirado do rio. A morte é originalmente pensada para ser um suicídio, mas Peeters suspeita de assassinato.

Elenco

Produção
La Trêve é produzida pela Helicotronc, em co-produção com RTBF e Proximus. Recebeu 1,18 milhões de euros (1,5 milhões de dólares) do novo fundo federado da Federação de Bruxelas Wallonie - Fundo RTBF para as séries belgas e do fundo económico regional Wallimage Bruxellimage. A série é filmada nas Ardenas. É o primeiro drama criminal televisivo belga em língua francesa.

Lançamento
La Trêve estreou em 21 de fevereiro de 2016 La Une de RTBF, e recebeu uma audiência média de 22,5 %.

Música
A música "The Man Who Owns The Place" da banda belga Balthazar toca durante os créditos de abertura de cada episódio.

A partitura original composta por Eloi Ragot está disponível em plataformas digitais.

Distribuição internacional
 (Flemish): Canvas – 8 October 2016
: France 2 – 29 August 2016
: RTS – 22 June 2016
 /  / : Netflix – 21 December 2016

References

Ligações externas

La Trêve
La Trêve
La Trêve


LUXYOGA is the world's premiere luxury yoga vacation: a week of unparalleled instruction, first-class service and award-winning local cuisine at their gorgeous villa in the South of France. Focused yoga programs with premiere teachers and digital photo analysis develop awareness and understanding for profound progress during and after your time at the villa. At LUX, every delicious moment becomes a balanced and fulfilling way of life.
This "Resolution Intensive" will kick-start your new year!
On-site massage and concierge. All-inclusive. Transfers provided from Nice.
Space is limited to 15 yogis so reserve early!


As part of my ongoing effort to protect taxpayer dollars by rooting out waste, fraud, and abuse, I introduced legislation (H.R. 918) to stop individuals from abusing the system by "double-dipping" unemployment and disability benefits at the same time.
Under current law, some people can get both disability benefits and unemployment benefits. That just makes no sense! Think about it – disability benefits are for those who can't work and unemployment benefits are for those who can work. That's why I've introduced this common-sense legislation to protect taxpayers' dollars. It will help ensure Social Security disability benefits are only for those who truly cannot work and for which this safety net was designed to help – including the nearly 8,000 Collin County folks who are disabled. With the disability program going broke next year, Congress should stop this double-dipping and now.
Social Security's disability program is projected to be unable to pay full benefits in 2016. Earlier this year the House passed a measure offered by Johnson as part of its rules package. The measure would encourage Congress to work to fix Social Security by preventing Congress from raiding the retirement program to bail out the disability program.


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Get Upto 1000 ₹ Cashback Via Amazon Pay Electricity Bill Payment Offer. Do an Electricity Bill Payment of at least Rs.100 and win cashback ranging anywhere from Rs.10 to Rs.1000. Offer is applicable once per customer during the offer period. This is Same as Phonepe Electricity bill payment offer and Also Same as Google Pay Bill Payment Offer. It is a completely randomized selection based on which cashback will be issued. There is no manual intervention on deciding cashback amount for each customer. Cashback will be credited within 3 business days as Amazon Pay balance.
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Wow! It sounds like you are planning quite an incredible vacation, how exciting! Unfortunately, there are several types of reservations which do not show up in My Disney Experience. Like you, I like to have everything in one organized place, so I add notes to the corresponding days in my itinerary with the plans and confirmation numbers. It's not exactly the same, but it works.
Select "My Itinerary" in your My Disney Experience account and in the top left corner select the drop down menu next to "+add plans." The bottom option is "add a note." You can select the time, location, description and any details you want to include, and even share it with members of your My Disney Experience - My Family & Friends list.
Have an absolutely magical vacation, Kim. I am thrilled about all of your fun adventures. Please let me know if there is anything else I am able to assist you with.