text:
New Bedside Genetic Screen Yields Results In An Hour
A new point-of-care system accurately screens a patient's DNA for a single gene in an hour. The shoebox-sized device from Canadian-based Spartan Bioscience analyzes cheek swabs taken from heart attack patients for a common genetic variant, responsible for a potentially deadly reaction to the antiplatelet drug Plavix® (clopidogrel). As recently reported in The Lancet (unfortunately, the article is behind a paywall, but you can read the abstract here), the bedside system dubbed the Spartan RX enabled doctors to identify every patient in the study who was a carrier of the gene, allowing doctors to provide alternative medications for treatment. The device is the fruit of a joint venture with the University of Ottawa Heart Institute, which is Canada's largest cardiovascular center.
With plans to reduce analysis time by 50% and broaden the methodology to other genes, the Spartan device is a breakthrough for on-the-spot genetic testing and personalized medicine.
The story of the Spartan RX is a case in which the medicine is the sickness, not in a direct way, but in the sense that an administered drug in some patients does nothing because their body chemistry is different. When someone has a heart attack, it's a common procedure for a doctor to administer Plavix to prevent blood clots from forming, which could cause another heart attack or a stroke. This is done either within a few hours of the heart attack or after an angioplasty is performed to open up the arteries around the heart and a stent is installed to keep them expanded. Stents themselves promote blood clotting in certain patients, which is why some are designed to release antiplatelet agents themselves. In the U.S. alone, over a million stents are placed into patients every year, so this is an incredibly common procedure. Additionally, some patients take Plavix for up to a year, which is part of the reason why it is the second best-selling drug in the world (in 2011, it had $7 billion in revenue and it's about to become a generic drug, increasing its affordability).
However, patients with the genetic variant of the CYP2C19 gene, present in about 30% of Caucasians, 50% of Asians, and 55% of East Indians, have enzymes that are unable to activate Plavix, so the drug doesn't stop clotting. In fact, the study showed that patients who received a stent and were carriers of the variant were at a higher risk of death, stroke, or heart attack by as much as 42%. So the problem is that if patients can't activate the drug, it's as if they aren't taking anything. That means clotting can start right away, triggering another cardiac event (up to 50% occur within the first 48 hours). So the stakes couldn't be higher as the FDA issued a warning about Plavix in 2010 in regard to this problem.
So it's imperative that carriers of the genetic variant be identified and fast. Previously, the only option was to send a sample of the patient's blood out for analysis, which could take up to a week to get a result. But in the meantime, doctors were forced to gamble with Plavix.
Dr. Derek So, principal investigator on the study, and Dr. Jason Roberts from the University of Ottawa Heart Institute
But this latest report suggests that the Spartan RX changes all that and in an incredibly simple way. A nurse takes a cheek swab from a patient, even as the stent procedure is underway, and places the sample in the device. The sample is optically analyzed and an hour later, a printout provides the analysis of the genetic marker, even before the patient is ready for the first dose. By having such a straightforward methodology, it requires little additional training (30 minutes, according to the 200-patient study). And it's as sensitive and specific as standard DNA sequencing.
On top of being incredibly good news for anyone currently suffering or soon-to-be suffering with cardiovascular disease (and let's face it, that's a hell of a lot of us), the Spartan RX is the first step in rapid genetic analysis for the purpose of personalized medicine. Other genetic markers should be able to be screened with this methodology, allowing for even more bedside analysis for individualized care. As genetic research has implicated specific genes responsible for conditions, the bottleneck in genetic medicine has been shifting to the utility of this information in the clinical setting. Because the Spartan RX study was such a proof-of-concept investigation, it sets the standard for selecting genetic markers that can direct therapeutic decision-making in such a clear way.
The device is currently approved in Europe and is working on FDA approval in the U.S.; however, larger clinical trials will likely need to be conducted in order to demonstrate the utility of the device across a much larger section of the demographic and in a variety of clinical environments. Still, these initial results are very promising.
Hopefully, the day will come when every patient's genetic profile is immediately accessible so that all critical genes can be identified to determine the best treatment choices. Obviously, medicine isn't there yet, even as genetic testing becomes more convenient. But Spartan Bioscience has taken an important step forward in producing a device that, within an hour, allows doctors to fulfill that part in the Hippocratic Oath which says, "I will give no deadly medicine to any one if asked."
[Media: Spartan Bioscience, University of Ottawa Heart Institute]
[Sources: PRweb, Spartan Bioscience, Technology Review, The Lancet]


TEL AVIV -- The U.S. Army is considering a purchase of the Israeli-made Iron Dome air defense system. The Army is asking Congress for $373 million to purchase two batteries. The United States rarely purchases weapons from foreign countries.
If approved, the U.S. Army could receive the Iron Dome by 2020. The system would protect U.S. ground forces from unmanned air vehicles (UAVs), mortars, rockets, artillery and cruise missiles.
Rafael Advanced Defense Systems developed the Iron Dome system.


text:
Everything I Wanted (Andy Jarvis Remix) Billie Eilish Download 'Everything I Wanted (Andy Jarvis Remix)' on iTunes
WATCH: Roman Kemp And Kate Garraway Vow To Recreate I'm A Celeb's Jungle Radio
After the pair wowed fans with their stint with Jungle Radio, Roman Kemp and Kate Garraway vowed to bring back their show from I'm A Celebrity... Get Me Out Of Here!
Roman Kemp and Kate Garraway have promised to redo their Bush Tucker Trial, Jungle Radio, after the pair left I'm A Celebrity... Get Me Out Of Here!
The trial saw the Capital Breakfast host join Kate, as the pair hosted a radio show for the other campmates - including Caitlyn Jenner and Myles Stephenson - as they were covered in insects and snakes.
> WATCH: Roman Kemp Explains His Shock About Being In I'm A Celeb... Final
Capital hosted a party for Roman Kemp's return. Picture: PA Images
The Good Morning Britain host - who also presents a show on Smooth Radio - rang Roman Kemp via FaceTime on the first day back from Australia.
Roman hinted at a Christmas special of Jungle Radio, to Kate, to which she said "Hang on... Cockroaches on our heads?!"
She then seemed over the moon at the idea, after Roman assured her no creepy crawlies would be involved. "Yes! Absolutely yes! Can we do that?!" she questioned.
> Roman Kemp Opens Up About His Friendship With I'm A Celeb's James Haskell
Viewers of the ITV reality series were quick to praise the pair for their "fantastic" attempt at the trial, campaigning for them to do the show outside of the jungle.
"Roman Kemp and Kate Garraway should just be allowed to continue on with that jungle radio show, because it really seems to bring that camp alive. #ImACeleb," wrote one fan on Twitter.
Gold. Always believe in your soul. You've got the power to know. You're indestructible. ✌🏻
A post shared by Roman Kemp (@romankemp) on Dec 8, 2019 at 2:13pm PST
During the task, the remaining campmates were asked music-related questions and had to answer them correctly in order to win food and drink, whilst Roman and Kate were showered in bugs.
> Grab Our App For The Latest I'm A Celebrity News And Gossip!
Kate Garraway also caught up with Sonny Jay - after finishing fourth in the series - and said she was planning on hosting a party for the other campmates, as they all "got on so well".
"So we want to all get together and have a proper night out without TV cameras and just have a really good time," she added.
More I'm A Celebrity News
See more More I'm A Celebrity News
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Charlotte Crosby Fans Think Ryan Gallagher Romance On Australian I'm A Celeb Could Be 'Fake'
Charlotte Crosby Kisses Married At First Sight's Ryan Gallagher On Australian I'm A Celeb
Charlotte Crosby Joins I'm A Celeb Australia After Claiming UK Version 'Banned' Her
Jacqueline Jossa Shares Heartache Of Being Branded 'Fat Lauren Branning' When She Was Cast On EastEnders
Latest TV & Film News
See more Latest TV & Film News

redpajama_set_name: RedPajamaCommonCrawl


text:
Browse Category: Environment > Sensing
Predictive Controller that Optimizes Energy and Water Used to Cool Livestock
Researchers at the University of California, Davis have developed a controller that applies environmental data to optimizing operations of livestock cooling equipment.
Colorimetric Detoxifying Sensors for Fumigants and Aerosol Toxicants
Researchers at the University of California, Davis have developed a colorimetric sensor than can detect and detoxify fumigants simultaneously.
In Situ Soil Nitrate Sensor
The invention is used for determining in-situ nitrate concentrations in soil solution using either ISE (Ion Selective Electrode) or fiber optic spectroscopy when the liquid in the porous cup of the in-situ probe is equilibrated with surrounding soil solution through the diffusion process.
Ultra-Sensitive Polybrominated Diphenyl Ether (PBDE) Detector
Polybrominated diphenyl ethers (PBDEs) are a common brominated flame retardant, which are commonly found in consumer products. Because they are not chemically bound to polymers, PBDEs are blended in during formation and have the ability to migrate from products into the environment. Studies suggest that PBDEs pose potential health risks such as hormone disruptors, adverse neurobehavioral toxins and reproductive or developmental effects. For this reason it is important to have the capability to sense the presence of PBDEs even in low concentrations.
Metal Triazolites
UCLA researchers in the Department of Chemistry and Biochemistry have developed a novel metal-organic framework (MOF) using triazole ligands that allows for facile modification with a variety of metals, which has unique gas separation and adsorption properties.
Multi-Tone Continuous Wave LIDAR
Object detection and ranging is a fundamental task for several applications such as autonomous vehicles, atmospheric observations, 3D imaging, topography and mapping. UCI researchers have developed a light detection and ranging (LIDAR) system which makes use of frequency modulated continuous waves (FMCW) with several simultaneous radiofrequency tones for improved speed of measurement while maintaining robust spatial information.
Automatic Fine-Grained Radio Map Construction and Adaptation
The real-time position and mobility of a user is key to providing personalized location-based services (LBSs) – such as navigation. With the pervasiveness of GPS-enabled mobile devices (MDs), LBSs in outdoor environments is common and effective. However, providing equivalent quality of LBSs using GPS in indoor environments can be problematic. The ubiquity of both WiFi in indoor environments and WiFi-enabled MDs, makes WiFi a promising alternative to GPS for indoor LBSs. The most promising approach to establishing a WiFi-based indoor positioning system requires the construction of a high quality radio map for an indoor environment. However, the conventional approach for making the radio map is labor intensive, time-consuming, and vulnerable to temporal and environmental dynamics. To address this situation, researchers at UC Berkeley developed an approach for automatic, fine-grained radio map construction and adaptation. The Berkeley technology works both (a) in free space – where people and robots can move freely (e.g. corridors and open office space); and (b) in constrained space – which is blocked or not readily accessible. In addition to its use with WiFi signals, this technology could also be used with other RF signals – for example, in densely populated and built-up urban areas where it can be suboptimal to only rely on GPS.
Automated Immersion Mode Ice Spectroscopy
Ice nucleating particles (INPs) suspended in the Earth's atmosphere influence cloud properties and can affect the overall precipitation efficiency and predictability of cloud systems worldwide. INPs induce freezing of cloud droplets at temperatures above their normal freezing-point (~-38 C), and at a relative humidity (RH) below the normal freezing RH of aqueous solution droplets at lower temperatures. These INP induced variabilities influence cloud lifetime, phase, as well as cloud optical and microphysical properties. Developing a relational model of INPs in global climate models has proven challenging as existing instrumentation systems either require too much air volume (in real-time flow instruments) or exhibit too much temperature variability (in off-line frozen assay based instruments). Thus, there is a real urgency to address this unmet need.
Device-Free Human Identification System
In our electronically connected society, human identification systems are critical to secure authentication, and also enabling for tailored services to individuals. Conventional human identification systems, such as biometric-based or vision-based approaches, require either the deployment of dedicated infrastructure, or the active cooperation of users to carry devices. Consequently, pervasive implementation of conventional human identification systems is expensive, inconvenient, or intrusive to privacy. Recently, WiFi infrastructure, and associated WiFi-enabled mobile and IoT devices have become ubiquitous, and correspondingly, have enabled many context-aware and location-based services. To address the challenges of human identification systems and take advantage of the popularity of WiFi, researchers at UC Berkeley developed a human identification system based on analyzing signals from existing WiFi-enabled devices. This novel device-free approach uses WiFi signal analysis to reveal the unique, fine-grained gait patterns of individuals as the "fingerprint" for human identification.
A New and Cost-Effective Technology to Produce Hybrid-Glass/Optical Bubble Probes
The ability to accurately quantify gas volumes in liquid flows has important applications in environmental science and industry. For example, environmental processes that significantly contribute to changes in earth's climate, such as methane seeps from the sea floor and the exchange of gases between the ocean and atmosphere at the sea surface, demand precise sensors that are small and sensitive enough to measure the ratio of liquids and gases in these bubbly mixtures. These measurements also play a critical role in the operational efficiency of a wide variety of different engineering processes. Applications include, the monitoring the optimal amount of bubbled oxygen in the treatment of waste water and sewage, and the oil and gas industry, especially in undersea oil pipelines in the Gulf of Mexico alone, have spent billions of dollars annually on added refinement techniques to remove seawater that could be preventable if sensors were able to measure the ratio of crude oil, seawater and gas as the mixture is pumped through pipelines. These challenges exist in both research and industry because the current manufacturing process for making the needed gas/liquid probes have significant cost constraints. Clearly, there is a need for a new and cost-effective technology to produce these probes.
Hydrogen Gas Sensors Based On Patterned Carbon Nanotube Ropes
This is a fabrication method for hydrogen gas sensors; these sensors have more rapid response times and are more sensitive than current detection techniques.
GPS-Based Miniature Oceanographic Wave Measuring Buoy System
Oceanic monitoring helps coastal communities, economies, and ecosystems thrive. The coastlines and open oceans prove to be very important to maritime countries for recreation, mineral and energy exploitation, shipping, weather forecasting and national security. As solar power, GPS, and telecomm improvements have been made, directional wave buoys have emerged and set the standard in wave monitoring. Non-directional and directional wave measurements are of high interest to users because of the importance of wave monitoring for successful marine operations. Wave data and climatological information derived from the data are also used for a variety of engineering and scientific applications.
Novel Sensor to Transduce and Digitalize Temperature Utilizing Near-Zero-Power Levels
Temperature sensors are routinely found in devices used to monitor the environment, the human body, industrial equipment, and beyond. In many such applications, the energy available from batteries or the power available from energy harvesters is extremely limited, thus the power consumption of sensing should be minimized in order to maximize operational lifetime.
The Flying Wing Autonomous Underwater Glider Technology
The underwater glider can be categorized as an autonomous underwater vehicle (AUV) that does not rely on an electrically driven propeller, but relies on small changes in its buoyancy and wings to move up and down. The pitch and roll is controlled by using an adjustable ballast. The AUV has been quite useful for collecting oceanographic data due to its unique propulsion system that uses very little energy and its ability to be on a sampling mission for weeks to months.
Highly Stretchable & Flexible Electronic Sensors
A new approach to creating highly stretchable electronic devices using twisted conductive microtubules.
Sensitive Detection Of Chemical Species Using A Bacterial Display Sandwich Assay
96 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} Endocrine disrupting compounds are found in increasing amounts in our environment, originating from pesticides, plasticizers, and pharmaceuticals, among other sources. These compounds have been implicated in diseases such as obesity, diabetes, and cancer. The list of chemicals that disrupt normal hormone function is growing at an alarming rate, making it crucially important to find sources of contamination and identify new compounds that display this ability. However, there is currently no broad-spectrum, rapid test for these compounds, as they are difficult to monitor because of their high potency and chemical dissimilarity. To address this, UC Berkeley researchers have developed a new detection system and method for the sensitive detection of trace compounds using electrochemical methods. This platform is both fast and portable, and it requires no specialized skills to perform. This system enables both the detection of many detrimental compounds and signal amplification from impedance measurements due to the binding of bacteria to a modified electrode. The researchers were able to test the system finding sub-ppb levels of estradiol and ppm levels of bisphenol A in complex solutions. This approach should be broadly applicable to the detection of chemically diverse classes of compounds that bind to a single receptor.
Individual Identity Verified Through Device-Free, WiFi Based Framework
Researchers at the University of California, Davis have developed a device-free, WiFi based framework that can isolate individual identity, from a small group of users, simply by observing variations in WiFi signals through a user's gait.
Improved Energy Harvesting for Current-Carrying Conductors
There are an estimated 130 million wooden poles that support overhead power lines in the US. Extreme weather, aging, storms or sabotage can all lead to potential damage of these poles and power lines, which can leave large areas without basic necessities. Due to this risk, it's anticipated that power utility companies will deploy sensors and corresponding energy harvesters to better respond to potential damage of this critical electricity grid infrastructure. To address this anticipated mass deployment of sensors and harvesters, researchers at UC Berkeley have developed technology improvements to harvesting of electrical energy from energized conductors carrying alternating currents, such as those on overhead and underground power lines (as well as power-supplying conductors in offices and dwellings). These enhanced harvesters would improve the economics of deploying sensors across a national power grid. The Berkeley harvesters can readily provide enough power to supply wireless communication devices, energy storage batteries and capacitors, as well as sensors such as accelerometers, particulate matter measuring devices, and atmospheric sensors.
Distributed Dynamic Strain Fiber Optics Measurement For Use In Sensors
96 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:Calibri; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} Structural health monitoring (SHM) is becoming critical in structural engineering and geotechnical engineering applications in recent years. The use of fiber optic distributed sensors for SHM has the advantage of long sensing distance, distributed sensing information and small size. Distributed fiber optic sensors can be used to monitor distributed temperature and strain information but also has application for used in detection of seismic activity, security sensing, and traffic/railway/bridge monitoring. UC Berkeley researchers have developed methods and sensors for distributed dynamic strain measurement using optical fiber that results in a larger sensing signal, better signal-to-noise ratio and longer sensing distance up to a few km lengths. The system can take strain readings at every 4m along an 1km length optical fiber at 2.5 kHz sampling speed with a strain resolution of 30 microstrain.
RF-Powered Micromechanical Clock Generator
Realizing the potential of massive sensor networks requires overcoming cost and power challenges. When sleep/wake strategies can adequately limit a network node's sensor and wireless power consumption, then the power limitation comes down to the real-time clock (RTC) that synchronizes sleep/wake cycles. With typical RTC battery consumption on the order of 1µW, a low-cost printed battery with perhaps 1J of energy would last about 11 days. However, if a clock could bleed only 10nW from this battery, then it would last 3 years. To attain such a clock, researchers at UC Berkeley developed a mechanical circuit that harnesses squegging to convert received RF energy (at -58dBm) into a local clock while consuming less than 17.5nW of local battery power. The Berkeley design dispenses with the conventional closed-loop positive feedback approach to realize an RCT (along with its associated power consumption) and removes the need for a sustaining amplifier altogether.
Shaped Piezoelectric Micromachined Ultrasonic Transducer Device
Piezoelectric Micromachined Ultrasonic Transducers (pMUTs) have attracted industry attention for their good acoustic matching, small geometry, low cost-by-batch fabrication, and compatibilities with CMOS and consumer electronics. While planar pMUTs have reasonable performance over bulk piezoelectric transducers, certain deficits remain in terms of coupling and acoustic pressure outputs, DC displacements, bandwidth, and power consumption. To address these deficiencies, researchers at the University of California, Berkeley, have developed a next generation of shaped pMUTs which are no longer fully defined by resonance frequency and can accommodate larger pressure outputs and bandwidths. This new pMUT apparatus can significantly boost overall performance while dramatically reducing power as compared to flat diaphragm state-of-the-art pMUTs.


Re: PEACE BE WITH YOU, May God bless you as you read. Receiving this message might sound to you as a surprise.I seek your great assistance to realize a project for the benefit of the poor orphans. Each day that passes by, I felt no improvement in my health as I do not know whether I will survive having undergone several surgical operations as a result of this incurable sickness (terminal cancer). The only help I need from you at this point is to be in constant prayers with me. To also assist me to transfer my funds (10,000,000 EUROS) and use it to help the less privileged. This is a huge responsibility to handle, but I do pray that God will give you strength to handle it. You will also be highly compensated. I looking forward to reading from you.


A creepy 5 foot long hanging evil skeleton skull head reaper ghost with evil LED eyes that light-up and flash in multiple colors, blue, red, green, purple, yellow and white!
This hanging creepy ghost is clothed in black and draped with tattered gray creepy cloth. Hang him up to frighten unsuspecting victims.
The ghost produces no sounds, but only a pair of strange flashing eyes that makes you wonder, if you're looking at it, does it look back at you?
A switch activates this spooky reapers flashing eyes to entice people to come near. He has a wide 4 foot arm span, and the arms can be bent and posed.
A creepy 5 foot long hanging evil skeleton skull head reaper ghost with evil LED eyes that light-up and flash in multiple colors, blue, red, green, purple, yellow and white! This hanging creepy ghost is clothed in black and draped with tattered gray creepy cloth. Hang him up to frighten unsuspecting victims. The ghost produces no sounds, but only a pair of strange flashing eyes that makes you wonder, if you're looking at it, does it look back at you?


Blocked drains Catford cleared for a set price Chris 0791 7852384.
We have been unblocking drains toilet / sink and sewer drains as well as rainwater pipes in the area for over 28 years and also cover the surrounding areas at no extra costs Bromley,Lewisham,Mottingham,Forest Hill,Brockley,Beckenham.
We don't charge an hourly / half hourly rate , we will give you a fixed price to unblock your blocked drains in Catford over the phone.
We have over 60 years experience between the two of us of clearing blocked drains and blocked toilets and sewers , we will ask a couple of question about were your drain is situated and using our knowledge give you a fixed price over the phone to unblock your drain.
We stick by our prices for blocked drains in Catford and please note we are not a large or national company, we believe we offer a service that a lot of large drainage company's cannot compete with as we are the owners who answer the phone, we are the people that will turn up to your property and we pride ourselves on the service we provide.
As well as unlocking drains in Catford we can also provide you with drain inspections using our self leveling drain camera to provide you with a drain cctv survey, which can be recorded onto a memory stick to view or email on your computer.
We also can unblock blocked toilets and sinks in Catford for fixed prices and have all the right tools for every type of blockage we come across.
We have perfected our methods of clearing blockages over all the years we have been clearing blockages, and with all the right tools assisted by over 60 years combined experience.


18 year old Borrego brings his love of Tolkien to the stage as the youngest director at the Grove Theatre presenting "The Hobbit". The future of Middle Earth is in good hands with young people showing this enthusiasm.
"Borrego loves J.R.R. Tolkien's tales of Middle-Earth, including 'The Hobbit' ".
To find out more follow Clare Lennon's blog.
Malachi Skjeie, who plays Bilbo Baggins in the play "The Hobbit," works on his part during the rehearsal.


text:
Q: Why is Visual Studio 2019 UWP XAML Designer showing a blank screen? I am trying out UWP, so I downloaded the Windows BuildCast UWP test app, and was trying it out but was completely unable to use the XAML Designer! Below is the error (as an image)

and as text ~
System.NullReferenceException
Object reference not set to an instance of an object.
   at Microsoft.VisualStudio.DesignTools.UwpSurfaceDesigner.Views.UwpIsolatedImageHost.UwpVisualWrapper.CreateWindowCore()
   at Microsoft.VisualStudio.DesignTools.XamlSurfaceDesigner.Views.DisabledHwndHolder.CreateHandle()
   at Microsoft.VisualStudio.DesignTools.UwpSurfaceDesigner.Views.UwpIsolatedImageHost.UwpVisualWrapper..ctor(IntPtr parentHwnd, IDCompositionDevice device, UwpSurfaceProcessDocument document, CancellationToken token)
   at Microsoft.VisualStudio.DesignTools.UwpSurfaceDesigner.Views.UwpIsolatedImageHost.UwpHwndHost.CreateSurfaceHwnd(IntPtr parentHwnd)
   at Microsoft.VisualStudio.DesignTools.XamlSurfaceDesigner.Views.IsolatedSurfaceImageHost.IsolatedHwndHost.BuildWindowCore(HandleRef hwndParent)
   at System.Windows.Interop.HwndHost.BuildWindow(HandleRef hwndParent)
   at System.Windows.Interop.HwndHost.BuildOrReparentWindow()
   at System.Windows.Interop.HwndHost.OnSourceChanged(Object sender, SourceChangedEventArgs e)
   at System.Windows.SourceChangedEventArgs.InvokeEventHandler(Delegate genericHandler, Object genericTarget)
   at System.Windows.RoutedEventArgs.InvokeHandler(Delegate handler, Object target)
   at System.Windows.RoutedEventHandlerInfo.InvokeHandler(Object target, RoutedEventArgs routedEventArgs)
   at System.Windows.EventRoute.InvokeHandlersImpl(Object source, RoutedEventArgs args, Boolean reRaised)
   at System.Windows.UIElement.RaiseEventImpl(DependencyObject sender, RoutedEventArgs args)
   at System.Windows.UIElement.RaiseEvent(RoutedEventArgs e)
   at System.Windows.PresentationSource.UpdateSourceOfElement(DependencyObject doTarget, DependencyObject doAncestor, DependencyObject doOldParent)
   at System.Windows.PresentationSource.OnVisualAncestorChanged(DependencyObject uie, AncestorChangedEventArgs e)
   at System.Windows.UIElement.OnVisualAncestorChanged(Object sender, AncestorChangedEventArgs e)
   at System.Windows.Media.Visual.ProcessAncestorChangedNotificationRecursive(DependencyObject e, AncestorChangedEventArgs args)
   at System.Windows.Media.Visual.FireOnVisualParentChanged(DependencyObject oldParent)
   at System.Windows.Media.Visual.AddVisualChild(Visual child)
   at System.Windows.Controls.Decorator.set_Child(UIElement value)
   at Microsoft.VisualStudio.DesignTools.XamlSurfaceDesigner.Views.IsolatedSurfaceImageHost.<CreateSurfaceAsync>d__66.MoveNext()
--- End of stack trace from previous location where exception was thrown ---
   at Microsoft.VisualStudio.Telemetry.WindowsErrorReporting.WatsonReport.GetClrWatsonExceptionInfo(Exception exceptionObject)

System.AggregateException
One or more errors occurred.

I've tried a few things -

*

*Visual Studio Installer -> Repair

*Checking for Environmental Variables (HPD or MCD)

*Running VS as Administrator

*Trying to get VS from Preview channel to test this out

*Restarting Visual Studio after toggling Show XAML Designer

*Changing the Target Versions to at least 3 different versions

EDIT: I tried with a new blank UWP C# app, and got this error

redpajama_set_name: RedPajamaStackExchange


Granit Xhaka and Laurent Koscielny face late fitness tests for Arsenal's trip to Everton on Sunday, go on Sky Sports.
Defender Koscielny (bruised foot) and midfielder Xhaka (groin) are assessed whereas George Lucas Torreira is suspended.
However, midfielder Aaron Ramsey is predicted to be accessible when coaching on Fri following a groin issue.
With Tottenham and Manchester United not in action this weekend, the Gunners will strengthen their place within the prime four within the Premier League with ending.
A win would see them move up to 3rd, 2 points on top of Spurs.
Manager Unai mineral said: "Each match is incredibly necessary for that.
If we tend to win we tend to square measure third. we would like to win therefore we are able to hold this position. however it's a protracted manner.
Hector Bellerin, Rob Holding and Danny Welbeck square measure long-run absentees for Arsenal.
Everton don't have any contemporary injury considerations as they appear for a 3rd win in an exceedingly row.
Defender Yerry myna bird misses out with a thigh injury whereas Marco woodland says goalkeeper Jordan actress is within the right frame of mind to face Arsenal when being concerned in an exceedingly scuffle last weekend.


LADY JUSTICE M. KIREJU. J.A.
On the 11th December 1997 we upheld the preliminary objections raised by learned Counsel for the respondent Mr. Ben Wacha and reserved our reasons. We now proceed to give those reasons.
This petition was brought by Athanasiua Kivumbi Lule against Pinto Manuel, for a declaration under Article 80 of the Constitution of the Republic of Uganda 1995, that Pinto Manuel was not academically qualified to be nominated and elected as a member of Parliament and was therefore sitting in Parliament illegally.
"(1) that Pinto Emanuel, the respondent, is currently a member of Parliament for Kakuuto County where the petitioner was born?
(c) to order fresh elections for Kakuuto County J He also prays that the respondent should be made to pay costs of the petition.
further alternative that the petition is bad in law for not joining the Returning Officer and in that it is irregularly before the court."
Consequently the respondent prays that the petition should be struck out with costs.
In the supporting affidavit, the respondent had attempted to show that he was academically qualified to be nominated and elected as a member of Parliament, but in view of the events that turned out when the petition came up for hearing, we did not think it was necessary to detail them.
At the hearing learned Counsel, Ben Wacha, the leader of the advocates who represented the respondent, raised four preliminary points which we considered were unassailable.
The first objection was that on the face of it the petition was brought under Article 80 (1) (c) of the Constitution. It was the contention of Counsel that article 80(1) (c) neither created jurisdiction for this court, to entertain the Petition, nor gave any litigant a right of access to this court on matters concerning elections of members of Parliament. This court is a special court created by article 137 of the Constitution to deal with matters specifically mentioned under that article. Declaration under article 80(l)(c) of the Constitution is not one of them.
has completed a minimum formal education of Advanced Level standard or its equivalent."
The article plainly neither clothed tills court with jurisdiction to investigate any matter under the article, nor gave any litigant a right of access to this court on matters concerning elections of members of Parliament.
The right of access to this court is contained in two legal Notices passed under The Judicature Act, 1996. The first one is The. Interpretation of The Constitution (Procedure) Rules, 1992 (Modification) Directions 1996, Legal Notice 3 of 1996.
"Directions shall apply to the Constitutional Court in exercise of its jurisdiction under clause (5) of article 137 of the Constitution, where the matter comes before the court by reference from another court."
refer the question to the Constitutional Court for decision in accordance with Clause (1) of this article."
It is clear from the above provisions that legal Notice No. 3 of 1996 deals with matters referred to this court sua motu by a trial Judge or on an application by a party to the proceedings before the trial court.
This matter did not come to this court following a reference from another court. It means that this court cannot entertain the petition under Legal Notice No. 3.
'"These Directions may be cited as the Rules of The Constitutional Court (Petitions for Declarations under Art 137 of the Constitution) Directions, 1996.
a declaration or redress under Clause 3 of article 137 of the Constitution."
This petition was not brought under any of the procedural rules for bringing matters before this court. We do not think that failure to bring the petition under the correct article of the Constitution through the correct procedural rule is a mere technicality.
we are not persuaded that the Constituent Assembly Delegates. intended to wipe out, the rules of procedure of our courts. by enacting Article 126(2)(e). Para (e) contains a caution against undue regard to technicalities. We think that the article appears to be a reflection of the saying that rules. of procedure are handmaids to justice - meaning that they, should be applied with due regard to the circumstsnces of each case".
who relies on the provisions of article 126 (Z)(e) must satisfy the court, that in the circumstances of the particular case before the court it was not desirable to pay undue regard to a relevant technicality. Article 126 (2) (e ) is not a magic wand in the hands of defaulting litigant".
The first objection accordingly succeeded.
It was contended in the second objection that the petition was time barred. The petitioner is contesting the election of respondent as a member of parliament on the grounds that the respondent did not have the minimum formal educational qualification to be a member of Parliament. Nominations for candidates for elections were held in May 1996. The elections were held in June 1996. The petition should have been filed within 30 days either after the Nominations or within 30 days after the declarations of the results of the elections. This petition was filed on the 11th April 1997, when no extension of time had been applied for and granted. Even if this Court had jurisdiction to entertain the Petition, the same would have been time barred.
We thought there was merit in the second objection. Hale 5(1) of The Parliamentary Elections (Election Petitions.) Rules, 1996 requires election petitions to be filed within 30 days after the declaration of the result of the election. The results of the elections in this case were declared in June 1996. The petition ought to have been filed the latest in July 1996. This petition was filed on the 11th April 1997. It was accordingly not filed within 30 days after the results were declared.
The third and 4th objections are that this court has no jurisdiction to entertain the petition and therefore not competent to make the declarations prayed for in the petition.
The Second method is to petition direct to the High Court. This jurisdiction is given to the High Court by Art 86 of the Constitution. Any person aggrieved by the determination of the High Court, may appeal to the Court of Appeal under Art 86(2), whose decision is made final by S 96(3) of Statute 4.
It is clear therefore that both the Constitution and Statute No. 4 of 1996 have established courts with jurisdiction to hear and determine election petition. This court is not one of them.
We do not agree with learned Counsel for the petitioner that this court can examine the qualifications of the respondent and if it was found that he lacked the requisite qualifications, to declare that he cannot be a member of Parliament. If this court does that, it will be assuming a jurisdiction not given to it either by Parliament or any law. This court is a creature of the Constitution and cannot exercise any jurisdiction not given to it by law.
We therefore agreed that this court had no jurisdiction in the matter. The third and forth objections were upheld.
County. It is the contention of the respondent that, that was not enough to clothe the petitioner with authority to bring the petition.
a registered voter in the Constituency concerned supported by the signatures of not less than five hundred voters registered in the constituency.
The petitioner did not say that he was a losing candidate in the election in dispute. There is nothing in the petition to show that he is a registered voter in the Kakuuto County, Rakai District. The petitioner also did not have, when he should, the support of five hundred signatories from the constituency. All these points were conceded by learned Counsel for the petitioner. Nevertheless, he submitted that locus Standi was not relevant as the petition was not an election petition.
a registered voter in the Kakuuto County and supported by the signatures of not less than five hundred voters registered in the Kakuuto county. Since the petitioner did not satisfy either of the above requirements, he had no locus standi to bring the petition. The fifth objection therefore succeeded.
Consequently all the objections are upheld. It was for these reasons that we struck out the petition on the 11th Dec. 1997.
Before we take leave of this case, we would like to urge advocates to take Constitutional matters to competent Courts. When matters are brought to this Court when they should not, then this Court may be constrained to penalise advocates concerned in costs personally.
I certify that this is the true copy of the original.


We develop mass-media campaigns to help people understand the harms of smoking and support smokers to quit.
Browse the current and past campaigns and find out more about reducing smoking in NSW.
The Never Give Up Giving Up campaign aims to increase hopefulness and self-efficacy in smokers by informing them that it is normal to make several quit attempts before ultimately succeeding.
Win is a new supportive push style anti-tobacco campaign targeting smokers aged 18 to 54 years in NSW. The campaign will run from 22 October to 2 December 2017.
Mick speaks about his smoking-caused illness and the direct effects of emphysema on not only him, but his family.
What's Worse focuses on the difficult situation of a mother communicating the realities of her illness to her young children.
The Aboriginal Quit Smoking campaign promoted the Aboriginal Quitline telephone service and the iCanQuit website.
The 16 Cancers campaign is an emotionally intense and graphic style campaign that encourages smokers to quit by highlighting that smoking has been linked to up to 16 different types of cancer.
Best Intentions demonstrates the regret of not quitting and the impact it can have on other members of your family.
The Bronchoscopy Campaign encouraged smokers to quit by focusing on a well-established health consequence of smoking—lung cancer.
The Bubblewrap campaign highlights the damage that smoking can do to your lungs.
Cigarettes Are Eating You Alive used graphic images to highlight the real health consequences caused by smoking.
This 60-second television commercial highlights the health consequences of smoking, in particular Emphysema.
Get Off Cigarettes highlighted how to get support quitting smoking in NSW.
The iCanQuit campaign demonstrates the value, importance and role of willpower in quitting smoking.
If Smoking Was A Friend challenges smokers to reflect on their relationship with their cigarettes.
The Many Diseases campaign presents a series of memorable scenes from existing anti-tobacco campaigns.
Mutations is a powerful and graphic campaign encouraging smokers to quit by showing how mutations in the body caused by cigarettes can lead to cancer.
The Quitline Services campaign informed smokers about the services and support available through Quitline 13 7848 (13 QUIT).
The Sponge campaign demonstrated the damage that occurs each time a smoker inhales cigarette smoke.
The Stairway to Emphysema campaign aimed to encourage smokers to quit by focusing on a well-established health consequence of smoking—emphysema.
The Terrie campaign is a hard hitting testimonial from a 52 year-old former smoker diagnosed with oral and throat cancer.
We Can Quit had friends and family of smokers, and Australian celebrities quit something in support of them quitting smoking.
This campaign encouraged smokers to consider their reasons for quitting by sharing personal stories from former smokers.


People are exhorted every day – exercise, exercise, exercise. Many patients I see are annoyed. Why should I bother? they ask. How much difference can it make?
Next they're told it will increase their lifespan; lower their blood pressure; decrease the risk of heart attack and stroke; lower the risk of cancer; help treat or prevent depression.
That's all well and good, they reply. But why does it really work?
There are many reasons. Yet some of the new data deliver a potent message that can aid overall health – physical activity makes regeneration more efficient.
What happens to the byproducts of cellular life? The "garbage" that's left over gets recycled.
The process is known as autophagy – literally "self-eating." Studies of how it works help explain why the human heart is mostly regenerated within 3 days.
Your body uses its "waste" products very efficiently. Animals where autophagy is turned off die.
Recent studies point to exercise making autophagy faster and better.
Recent work from autophagy researcher Beth Levine at Southwestern Medical School in Dallas has looked at cell recycling in mice.
Mice were put on the treadmill. The longer they pedaled, the more autophagosomes – cell organelles that recycle cellular waste – appeared. The autophagosomes seemed to recycle more efficiently.
Through a marvelous trick, the researchers then made mice who did not grow new autophagosomes with exercise.
Those mice didn't do as well.
The modified mice did not take up as much glucose when they moved. Their physical endurance was less.
The normal mice seemed to do a better job at getting rid of old mitochondria – the energy packs of the cell.
And as the Economist reported last week, this ability may be related to delaying aging. Animals put on very low calorie diets (hasn't yet been proven for humans) live longer.
How does calorie restriction work? Increased autophagy is at least part of that story.
Recycle quickly and effectively and you regenerate well. Animals live longer.
Is this one way exercise aids health?
As was also reported a few weeks ago, mice who exercise change white fat to brown fat. Brown fat metabolizes far more quickly.
The mice sporting increased brown fat had better glucose control. Fatty diets did not make them gain weight.
In the experiments that looked at brown fat – as in the autophagy experiments – exercise increases physiologic effectiveness. And when it came to fat, similar results seemed to occur with people.
So exercise increases efficient autophagy. It also increases conversion of fat to a different, faster burning type.
Unappreciated in many of the studies showing positive effects of vitamin D are the "confounding" effects of light.
Light increases vitamin D. But it is very much drug on its own.
Light tends to make moods better. Light, particularly sunlight, shifts biological clocks. Light increases natural killer cell activity.
And people who are physically active get more light.
Multiple studies show light changing the effects of exercise. For example, morning light plus exercise appears to be a very good way of helping people sleep better. Light plus exercise also increases the "tightness" of biological clocks.
Light appears to have its useful effects on regeneration, too.
Exercise has been extolled for health for a long time. It increases blood flow, which supposedly "cleanses" the body of toxins. It changes overall fluid balance, and propels muscle, sinew and bone to higher metabolic levels.
Yet what exercise really seems to do is help increase your capacity to regenerate your body.
It improves recycling. It changes tissue. It builds muscle. It decreases fat buildup in arteries. It appears to decrease inflammation.
It makes the body's basic job of replacing and renewing itself more efficient.
Humans evolved to move. We enjoy doing it. When we do it we experience more "flow" and peak experiences.
We even look better. It really pays to use your body the way it's built.


Currently a mother and a wife who loves reading. Formerly a middle school math teacher who kept too busy and stressed out to read. My husband and I are missionaries in Lebanon.
It has been a crazy transition back to Lebanon. This post is going to very quickly and visually show you our lives, and I am going to share a few of my favorite things right now that are helping us master our lives!
This post does contain affiliate links, which will make it super fun if you purchase any of the things through this page because I will get a percentage with no extra cost to you!
We came back to Lebanon and found out that Kyrie Rebekah is allergic to sesame seeds.
The light bulbs started going on in my brain! Hummus is made with chickpeas and tahini, and in my desire to keep Kyrie eating, I had bought her a tub of hummus. No, I am not going to put an affiliate link for hummus here because there is no way it would taste as good as hummus from the Middle East. If you want good hummus, you will just have to visit us!
With that discovery, Kyrie has been fine, and all is well. Full health has returned to her, and she no longer feels sick.
What are my favorite things to get through this time of stress?
My daily devotional which I have been reading all year, and think is amazing!
The devotional I have been using all year is the Moravian Daily Text for 2017. I mentioned this in a previous post sharing how my desire to Belong in my own skin has included searching into my heritage of being Moravian. Moravians were the founders of 24/7 prayer, and forged the way in so many missions movements. Each day has a verse from the Old Testament and New Testament along with a selection from a hymn for each verse. The text for the day ends with a prayer. It is encouraging to know there are so many others reading that same text and praying that prayer along with me every single day. I am so encouraged, and strive to do as Bonhoeffer asked his seminary students at Finkenwalde, to refuse to rise from the reading until my heart has shifted toward God.
Bath & Body Works, Signature Collection Body Lotion, Dark Kiss, 8 Ounce I love having a lotion that can make me feel calm and beautiful. This lotion is my favorite in the whole world! If you click through to buy you will make it even more my favorite because I will make a small amount of money and also will know that someone will be feeling as good as I feel when I use this lotion. Do yourself a favor and get some Dark Kiss, it is amazing!
This next fun item, I have never seen in America, and I am so excited to share it because all of my friends back home can have a taste of Lebanon in America because of Try Amazon Prime 30-Day Free Trial ">Amazon!
Lion Bars are our go to grocery store treat. When we take the kids shopping we all get one small treat for getting through the ordeal. If you haven't taken our grocery store challenge to learn how to shop like you live in Lebanon, go put it on your calendar now. And if you just want a candy we commonly eat, go ahead and try Lion Bars.
Finally, I will end with a treat that we have never seen here until now. Tension Tamer is my all time favorite tea from Celestial Seasonings. When Louis and I went on the tour through the Celestial Seasonings in Boulder, the tour guide tried to stump the group by asking, "Which tea has hops?" I knew right away, and also the other strange ingredients that make up my favorite tea. If you haven't had this amazing, unique blend, try it today. It truly does tame my tension.
Thus ends my post meant to bring a smile to your face, reassurance that we are all alive and well, and give you a taste for our lives here figuratively as well as literally.
And one final word about Amazon. I love Amazon. Being able to ship things to our families and friends for birthdays and holidays with no shipping costs because of Try Amazon Prime 30-Day Free Trial ">Amazon Prime has been a lifesaver for us. Now the video and book services have made it even a better deal. So, yes, if you get Try Amazon Prime 30-Day Free Trial ">Prime or any of these other fun items from this funny post, I will make a tiny bit, but also it is so worth it.
I read a fantastic book called The Great Passage, by Shiwon Miura. It was such a well-crafted book, and made me care about dictionaries and words quite a bit. Worth a read for any book lover.
This week was another Fit Test, since 15 days had passed. I had a funny weight loss story happen when weighing in. I weighed in and realized I had gained 4 pounds! I was disappointed, but know that weight can fluctuate throughout the days, and it isn't that big of a deal. I am feeling like I look better, I am feeling stronger, I have increased stamina, so all of my goals are being reached regardless of 4 lbs. A few days later the kids wanted to be weighed, and Davy was asking how to read the scale. As I was showing him I realized I had read the scale backwards! I had added weight when it had actually been 4 lbs I lost.
I lost 4 lbs in the last 2 ½ weeks.
I also lost inches in my waist and hips.
Here are two of my #BBM6.0SweatySelfie's. My arms are getting toned!
I have been building a habit of practicing every day, and I feel like it is really helping my brain to feel success.
This brings me up to 34 posts out of my goal of 52 posts. So I am at 65% of my goal. This is fantastic progress as I am writing every day now in a regular habit.
Sunday marked the beginning of our newest Quarterly Prayer Challenge Week, so I have been hard at work all week preparing the in depth emails which will be sent only to the small group committed to our Prayer Warrior Team! CLICK HERE if you would also like to join that Prayer Warrior Team and commit to praying for our ministry in Lebanon this week!
Since we are entering full prep for travelling, I want to continue to read. Reading The Great Passage this week allowed me to stay calm and not spend every minute working to burn myself out. I hope to read another book this week that is a novel to relax.
I need to work on the Prayer Challenge. There will be posts on the blog with a general description of prayer needs, but only the Prayer Warrior Team will receive the in depth explanation of what we are seeking prayers for.
Additionally, I will not be taking the laptop with me to the States because we need to buy a new one for Louis, so I am hoping to schedule blog posts ahead so that there is at least one a week while we are traveling and getting settled. This means writing multiple posts and continuing to be consistent while preparations increase for travelling.
This week I am diving into sending emails to set up appointments with people for my time in America. Several big dates have to be decided, and I am seeking God's guidance and wisdom for making wise decisions.
Today, Monday, is the last day of school for Davy. We opted out of his class trip because it is an extremely expensive picnic, and because Louis' work schedule was going to mean that the first two days of summer vacation he wouldn't be around. We are going to have a family picnic in our living room instead so we can spend time with Daddy before heading for America. We hope it can be a fun day to relax as a family.


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text:
Q: NSJSONSerialization parse error - unrecognized selector This is the code:
NSString *jsonString = @"[
            {\"sn\": \"E\", \"t\": \"K\", \"d\": \"Tue 3-Mar\"},
            {\"sn\": \"F\", \"t\": \"Y 1\", \"d\": \"Tue 3-Mar\"}
         ]";
NSData *data = [jsonString dataUsingEncoding:NSUTF8StringEncoding];
NSArray *jsArray = [NSJSONSerialization JSONObjectWithData:data options:0 error:nil];
NSLog(@"jsArray: %@", jsArray);

for (id job in jsArray) {
    NSLog(@"job: %@", job);
    NSLog(@"%@", [job sn]);
}

In the console, I get this:
2014-04-22 15:40:46.464 test[2442:60b] jsArray: (
        {
        d = "Tue 3-Mar";
        sn = E;
        t = K;
    },
        {
        d = "Tue 3-Mar";
        sn = F;
        t = "Y 1";
    }
)
2014-04-22 15:40:46.466 test[2442:60b] job: {
    d = "Tue 3-Mar";
    sn = E;
    t = K;
}
-[__NSCFDictionary sn]: unrecognized selector sent to instance 0x8fa53b0
*** Terminating app due to uncaught exception 'NSInvalidArgumentException',
reason: '-[__NSCFDictionary sn]: unrecognized selector sent to instance 0x8fa53b0'

It seems to recognise the array of objects and the individual object. Why does it object to the property sn?

A: The jsArray contains dictionaries. So job is an NSDictionary. NSDictionary doesn't have a method named sn. If you want the value for the key @"sn" then you need:
for (NSDictionary *job in jsArray) {
    NSLog(@"job: %@", job);
    NSLog(@"%@", job[@"sn"]);
}

A: Your jsArray contains NSDictionaries, So the type of job will be NSDictionary.
You can't retrieve value from NSDictionary like that.
Use:
 NSLog(@"%@", [job objectForKey:@"sn"]);