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Dans l'embryon vertébré, un rhombomère est un neuromère du tube neural en développement dans la région du rhombencéphale. Les rhombomères apparaissent comme une série de gonflements légèrement rétrécis dans le tube neural, caudale par rapport à l'angle céphalique . Dans le développement embryonnaire humain, les rhombomères sont présents au jour 29.

Au nombre de huit chez l'humain, les rhombomères déterminent le schéma de la maturation du rhombencéphale. Les parties finales étant le pont, le cervelet et la moelle .

Fonction
Dans les premiers stades de développement du tube neural, la segmentation du neuroépithélium se produit. Cette segmentation se transforme en une série de neuromères. Chaque segment est appelé un rhombomère. Chaque rhombomère développe son propre ensemble de ganglions et de nerfs. Plus tard dans le développement, les rhombomères forment le rhombocéphale, qui forme le cerveau postérieur chez les vertébrés. Chaque rhombomère exprime son propre ensemble unique de gènes, dont il a été démontré qu'il influence les comportements rythmiques postnatals, tels que la respiration, la mastication et la marche.  Chaque rhombomère exprime une combinaison unique de facteurs de transcription, peut établir une différenciation neuronale spécifiques.

Les cellules qui forment les limites des renflements des rhombomères prolifèrent beaucoup plus rapidement que celles du milieu. Il est très difficile pour les cellules de passer d'un rhombomère à un autre, de sorte que les cellules ont tendance à rester dans un rhombomère.

Cartographie du destin neuronale
Chaque rhombomère donne naissance à un ou plusieurs types de neurones. Cependant, le destin du neurone ne dépend pas nécessairement de la segmentation. Les nerfs moteurs se forment en fonction de motifs rhombomériques, mais chaque type de nerf peut provenir d'un rhombomère ou d'une paire de rhombomères voisins. Les neurones vestibulospinaux se différencient dans trois rhombomères voisins, en particulier r4, r5 et r6.

Beaucoup de ces rhombomères ont été cartographiés dans une certaine mesure chez des espèces autres que l'homme. Par exemple, il a été démontré que les rhombomères 2 et 3 donne naissance au ganglion trijumeau, le rhombomère 2 donne le ganglion detrigéminal[./Rhombomère#cite_note-Delhaye-Bouchaud200173-2 [2]] tandis que r4 donne naissance au ganglion géniculé, ganglion spirale et ganglion de Scarpa. r5 et r6 donnent naissance au nerf abducens, et la partie inférieure de r6 et la partie supérieure de r7 donnent naissance au ganglion ptérygopalatin[./Rhombomère#cite_note-Delhaye-Bouchaud200173-2 [2]]. Enfin, la frontière de r7 qui n'est pas en contact avec r6 donne naissance aux ganglions jugulaires/nodoses. Ces cartographies, cependant, ne peuvent pas être appliquées à différentes espèces.

Des études ont montré que les premiers neurones sérotoninergiques ont commencé dans les rhombomères antérieurs. Le groupe de neurones le plus dorsal provient du rhombomère 1, et le raphé postérieur, qui se forme à partir des rhombomères, dériverait des rhombomères postérieurs à un stade légèrement plus avancé du développement embryonnaire.

Biomécanisme

Gènes hométiques
La position des rhombomère est due à l'expression des gènes homéotiques, c'est-à-dire chez les vertébrés les gènes Hox.

Le sort d'un rhombomère est affecté par l'expression différentielle du gène Hox. Par exemple, avec des mutations du gène Hox, les nerfs moteurs crâniens se sont formés à des endroits différents de la normale ou ne se sont tout simplement pas formés.

Expression des gènes homéotiques
L'expression des gènes Hox dans le rhombencéphale au cours de la segmentation est contrôlée par différents facteurs parmi lesquels l'acide rétinoïque, d'autres facteurs de transcription et les facteurs de croissance fibroblastiques ou FGF.

Un gradient d'acide rétinoïque émanant du nœud de Hensen ferai exprimer différents gènes Hox.

Plusieurs études ont montré que le facteur de croissance des fibroblastes (FGF) est sécrété à partir de la limite mésencéphale-rhombomère 1. Ces protéines instruisent le comportement cellulaire dans le neuroectoderme environnant. Cependant, le mécanisme derrière l'intégration du signal et les actions qui s'ensuivent restent flous. Des études ont montré que les récepteurs FGF, ou FGFR, agissent partiellement de manière redondante pour soutenir la survie cellulaire dans l'ectoderme dorsal, promouvoir l'identité tissulaire r1 et réguler la production de populations neuronales ventrales, y compris les neurones dopaminergiques du mésencéphale. Chez la souris, alors que les mutations de fgfr2 et fgfr3 n'ont pas interféré avec le développement du mésencéphale et de r1, la mutation de fgfr1 a causé des défauts du mésencéphale et de r1.

Chaque rhombomère a son propre ensemble de récepteurs, et les mêmes récepteurs peuvent provoquer des actions différentes.  Cependant, leur importance et leurs rôles spécifiques n'étaient pas clairs. En mutant les protéines Gli2 et Gli3, qui ont été particulièrement étudiées, il a été constaté que Gli2 et Gli3 contiennent à la fois des domaines d'activation et de répression, tandis que Gli1 n'avait que des domaines d'activation, qui étaient entièrement transcriptionnels. Gli2 s'est également avéré être un activateur plus puissant tandis que Gli3 était un puissant répresseur. Gli2 et Gli3 avaient des fonctions qui se chevauchaient et concernaient la structuration de la moelle épinière ventrale, ce qui était important pour une organisation et une formation correctes des motoneurones. Cela a été montré lorsque la mutation de la protéine Gli3 n'a montré qu'une légère diminution de l'expression d'Olig2, tandis que lorsque la protéine Gli2 a été mutée, l'expression d'Olig2 n'a pas été détectée. Olig2 est normalement exprimé dans la région ventrale du tube neural. Des mutations dans la protéine Gli2 provoquent des dommages plus graves dans la structuration ventrale du cerveau postérieur que celle de la moelle épinière. Cela montre que Gli2 remplit différentes fonctions dans le cerveau postérieur que Gli3 est incapable de remplacer. Gli2 et Gli3 dans un cerveau postérieur en développement ont également des fonctions distinctes dans la transduction du signal Shh (sonic hedgehog). Ceci est causé par une modulation différentielle de l'expression des gènes qui est spécifique à chaque rhombomère. Enfin, des études ont montré que dans le rhombomère 4, la structuration ventrale est moins affectée par la mutation de Gli2. Cela montre que ce rhombomère particulier a des exigences différentes pour les protéines Gli.

Il a également été démontré que les rhombomères peuvent affecter la position dans laquelle les neurones réticulo-spinaux et branchiomoteurs se développent. Chaque rhombomère peut provoquer un motif répété de neurones spécifiques aux rhombomères, y compris les neurones réticulo-spinaux, dont beaucoup partagent des propriétés telles que la localisation médiolatérale. Les neurones réticulo-spinaux occupent également différentes zones dans les rhombomères de différentes espèces. Il a été découvert dans une étude que les neurones réticulaires du cerveau postérieur de la lamproie, qui comprenaient des cellules isthmiques, bulbaires et de Mauthner, se développaient dans des positions conservées spécifiques aux rhombomères, similaires à celles du poisson zèbre. Dans différentes espèces, cependant, les neurones réticulo-spinaux occupent différentes zones dans les rhombomères. Il a également été démontré que les noyaux moteurs du trijumeau et du visage n'étaient pas bien corrélés avec les limites des rhombomères chez la lamproie.

Dans les rhombomères, des membres de la famille des facteurs de transcription T-box ont été associés au bon développement des cellules migrantes.  Pendant le développement du cerveau postérieur, il a été démontré que les corps cellulaires du trijumeau migrent dorsolatéralement dans les rhombomères 2 et 3, tandis que les cellules faciales se déplacent dorsolatéralement dans r5 près de la surface piale. Les neurones qui forment le noyau facial sont produits dans r4, mais se déplacent le long de l'axe antéropostérieur du cerveau postérieur dans r6, après quoi ils se déplacent dorsolatéralement. Les neurones vestibuloacoustiques sont également produits en r4. Cependant, ils ont un schéma de migration unique, où leurs corps cellulaires traversent la ligne médiane jusqu'au côté controlatéral. De cela, on peut conclure que plusieurs sous-classes de motoneurones sont produites à des endroits spécifiques dans le cerveau postérieur en développement. Tous sont liés par l'expression de Tbx20. Les motoneurones produits dans le cerveau postérieur ont Tbx20 exprimé sélectivement. Dans les mutations Tbx20, la structuration des régions des rhombomères et des motoneurones était normale lorsqu'il s'agissait de mutations conditionnelles et que les neurones étaient post-mitotiques. Les mutants Tbx20 pré-mitotiques ont montré de nombreuses déficiences de migration cellulaire, y compris une migration dorsolatérale anormale des cellules du trijumeau, un arrêt de la migration tangentielle des neurones faciaux et un manque de migration transmédiane des cellules vestibuloacoustiques.  Cependant, les motoneurones du cerveau postérieur dépourvus de Tbx20 ont conservé la capacité d'étendre les neurites à la périphérie. L'élimination complète du Tbx20 ne provoque pas le passage des neurones du trijumeau et du visage aux neurones hypoglosses. Il a été démontré que les neurones faciaux migrent tangentiellement de r4 à r6, tandis que les neurones trijumaux qui sont produits dans r2 migrent dorsolatéralement non radialement. Les cellules vestibuloacoustiques migrent le long de la ligne médiane à r4 de manière controlatérale dans le cerveau postérieur. Tbx20 semble avoir une activité transcriptionnelle dépendante du contexte. Cela signifie qu'il est capable de contrôler différents programmes de migration cellulaire spécifiques à différents types de cellules. Il doit pouvoir réguler ces schémas par différents moyens.

Chez d'autres espèces
Chez certaines espèces, les rhombomères sont évidemment segmentés et restent ainsi pendant une période de temps prolongée. Chez d'autres espèces, la segmentation finit par disparaître. Par exemple, les rhombomères sont détectables par microscopie optique dans la souche de souris Swiss/Webster jusqu'au jour embryonnaire (E) 10,5, mais ils disparaissent à E11,5. De nombreux rhombomères, comparés entre les espèces, ne forment pas les mêmes choses. Par exemple, r2 et r3 ont été mappés sur les motoneurones du trijumeau chez de nombreuses espèces. Cependant, toutes les espèces n'ont pas cette corrélation.

Chez la souris, il a été montré que la structuration du tube neural en segments rhombomériques peut réguler l'apparence spatiale et temporelle du réseau locomoteur spinal.

Alors que de nombreuses études ont été réalisées sur des rhombomères où les rhombomères d'une espèce sont greffés sur une autres, des imprécisions peuvent survenir. Une source possible est l'endommagement du rhombomère pendant le processus de retrait, de transport ou de greffage. Une autre source possible est le mélange des cellules d'espèces différentes après greffage des rhombomères, ce qui pourrait conduire à la contamination d'une région rhombomère par une autre, très probablement à partir des rhombomères voisins.

Voir aussi

Bibliographie

Ouvrages

Articles

Articles connexes
 Boîte homérique
 Neuromère

Notes et références

Embryologie
Embryologie du système nerveux

redpajama_set_name: RedPajamaWikipedia


A network of companies created specifically to participate in Expo 2015 Milan and promote the internationalization of Sicilian products. This is the challenge of Inside Sicily, founded in 2015 by the idea of the 33-years old businessman Stefano Massimino (photo) from Catania.
Inside Sicily is present in the market of Cascina Triulza with the products of 12 companies located in Sicily: Agromonte, Alicos, Bacco Srl, Caffè Morettino, Cantine Russo, Caseificio Passalacqua, Distilleria Fichera, Dolceria Rizza, I Peccatucci di Mamma Andrea, Oleificio Milano Srl, Pastificio Gallo, Terre di Miele.
"The companies come from all over Sicily - says Massimino - and each maintain their own brand. With the brand Inside Sicily they have the opportunity to help each other in the promotion of their products abroad. Each one gives a contribution to grow the network to which in the future also other companies will join".
The products of the companies of Inside Sicily are varied: cheese, coffee, wine, preserves, honey, liqueurs, jams, sweet creams, pesto, pistachio of Bronte, chocolate of Modica, cannoli, granite, cherry tomatoes, olive oil, pasta.
"They are all different companies, with quality products but not competitive - said Massimino -: we put on the network so that they can better promote their products abroad, with lower costs. We have already planned some exhibitions: in November we will go in Britain and then in 2016 in Brazil, Norway and Miami".


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Alli's Excellent Adventures!
La Paz, Bolivia, November 27, 2017
I had a fantastic day! I seem to be saying that a lot lately! La Paz is awesome! There is so much to see and today I went on a cable car tour with the best guide I've ever had! I was the only one so it was like my own private tour! Alfie never shut up the whole 3 hours and so I sure learned a lot!
La Paz has a population of 1.6 million and sits at an altitude of 3660 meters or 12,007 feet. It was founded in 1548 by Alonzo de Mendoza, a Spaniard. He soon seized the gold mines and became the city's first mayor.
Before my tour, I wandered. The public buses are fancy but not as pimped as in Guatemala-
Shoe shine men wear face masks and try to polish everything, including meshed runners-
San Francisco Church was built in 1548 by Fray Francisco de Los Angeles. It collapsed because of heavy snowfall in 1610 and was rebuilt between 1744 and 1753. In the front above the altar are mirrors that the Spaniards used outside the church to entice the Incas in because they had never seen themselves-
The outside architecture is so intricate and to incorporate Inca culture, they used animals and fruit-
There were protests most of the day. They blocked traffic, yelled and hollered. Apparently the engineering college doesn't think they need to study for the required number of years, so they're hitting the streets. They walk for hours. Each participating member must pick up a chip from the organizers and bring the chip to the next meeting to prove they attended the rally. If they don't have a chip, they are fined. Protests are a daily occurrence in La Paz-
While waiting for my tour to start, I visited the mercado. It's massive and most shops don't open until the afternoon. The baker said everything was 'fresco', but by the taste of what I tried, she was lying-
There are numerous restaurants in narrow container type rooms. The owner has enough food to feed about 25 people and when the food is gone, she shuts her doors. People crowd around the narrow table-
Fresh juices are also available-
One area is nothing but flowers-
I love how they present these roses-
Finally 10 am arrived and my tour began. Our first stop, after taking a collectivo most of the way to the cable car station, was the former train station which has been converted into the red cable car station-
Five lines are open: red, blue, yellow, green and purple. By 2025 there will be 11 lines. This is their version of a metro. They're unable to have a subway because there are 117 rivers running under the city-
It costs 55 cents to ride the cable car-
Building it was not without its problems. Anyone who was going to have it pass over their home was naturally upset-
One of the many protests-
The riot police made sure nothing got out of hand-
We passed over the La Paz Cementario. People are buried within 24 hours of dying. They are put into a slot for free for 2 years, after which time the family must either pay for longer storage or the body gets cremated for free. If the ashes aren't picked up, they will be put in a pile with all the other uncollected ashes-
La Paz is a city of either very rich or very poor people. Minimum wage is about $400 Canadian/month which is enough to survive. Bread costs .50 bolivianos and when there was talk it was going up to .60, there were massive protests because people could not afford that. Unions are very powerful and the biggest one is the coco leaf farmers. Coco leaves are consumed massively to combat altitude sickness.
Homes of the poor-
A few years ago there was a car accident involving 6 people. The car went off the road and somehow ended up trapped in a ravine-
The six people lived, however the driver had his legs amputated to get him out of the car-
Upon arrival in El Alto, we visited the witch's market. Across the street is a Catholic Church that has incorporated Inca symbols in its design. Notice the evil eye above the entrance-
At the witch's market is a monument of frogs. If frogs live in your yard, there must be a lot of oxygen so you too will be healthy. They are sitting on the Inca cross. The top row of the cross is for the afterlife, the middle row for the now and the bottom row for hell-
There are many witches who perform miracles-
They each have a fire pit-
where they burn eucalyptus and offerings made of sugar. You can buy multipacks of sugar asking for money, love, good health etc.-
or individual offerings-
The witch builds a fire, then puts the sugar offerings on top. She walks around the fire, sprinkling wine which represents blood. To conclude, she sprinkles sugar around the whole fire to keep everything inside-
This witch is very popular because she always has a lineup. It costs 1000 to 3000 bolivianos to see her. That's $184 - $552 Canadian/visit-
Mocha chinchi is made using peaches. It's a sweet energizing drink without sugar added but is still very sweet. The peach stone sits in the bottom-
The views from the cable cars are awesome-
People don't finish their buildings because as long as the top floor isn't completed, you don't have to pay property taxes for 10 years. So, families give their buildings away to other family members after 10 years so they can continue to avoid taxes for years. Property owners were pissed off with the cable car going over their property but one way to appease them was to put an advertisement on the roof. This way they make money-
Under 99% of all homes in the city is a buried llama foetus for good luck-
The Triple Bridge took a lot of time off of people's commutes to La Paz-
However, a homeless person was buried alive underneath the pillar with the condor painted on it. If the contractors of the bridge knew his/her family, the family would have received money. If the person was alone, they would have been tricked somehow before they met their fate. City hall has never denied this happened-
We got on the green line and went to Zona Sur or South Side, a suburb of La Paz that is very different-
because buildings are more North American: higher, with yards and pitched roofs-
On the way there are poorer areas-
but then we crossed over a gated community. This unfinished home has been for sale ever since the cable car went in-
These homes are massive and they have lawns which is special and expensive because of the climate: it takes a lot of work to grow grass-
Over the hill on our way down to Zona Sur, it was like a different world. There's a modern mall and few collectivos. In La Paz, there's a collectivo for every person! People actually own cars in Zona Sur and it's against the law to set up a booth of any kind on the sidewalk-
On our way back to our starting point in a collectivo, we just made it in front of the protest-
After the tour, I went for lunch in the mercado-
where I ordered Milanesa, the daily special. It included a delicious beef pasta soup-
salad, a chicken cutlet and a fried platano for $1.84-
The cook was pretty grumpy but her cooking was rico-
After lunch, I went to San Pedro Prison. I just started reading Marching Powder, a true story written by an Australian, Rusty Young, about Thomas, the king pin in the prison. Whole families live here in rich apartments with jacuzzis. Kids can leave to go to school and spouses can go to work. They manufacture cocaine and it's put into a Pamper and thrown out a window. Those in the know pick up the diaper and sell it! People can enter the prison with a bribe for the guards-
The main doors-
I took a picture of some of the prisoners before the guards told me I couldn't. There were quite a few people entering with bags of food and other items for the inmates-
After leaving the prison, I headed for the Cementario. Luckily, I saw a zebra. They're hired by the government to hang out on the streets and teach driver safety-
The La Paz Cementario-
People really personalize the tombs-
The notice explains that the family has only a certain amount of time to either pay for more storage or the body will be cremated-
Cleaning and adding to a tomb-
Carlos Palenque Aviles was a politician who helped the poor. Locals pray in front of his grave. He died at 52 from a heart attack-
Bolero hats have a long tradition. Apparently the Spanish brought them for the men but they were too small so women started wearing them. Today they cost anywhere from $184 to $550 Canadian so are worn for prestige. If they're on straight, that means the woman is married. If they're on slanted to the side, the woman is widowed or single. Also, the women wear large skirts that make them look quite fat but it's only layers underneath to imply they are fertile. Of course, the tradition of cholitos: traditional dress, is dying. Younger women want to dress like Westerners.
Women of La Paz-
Women carry an aguayo blanket like a purse on their backs-
I had a great day and have booked biking on the Death Highway for tomorrow! Looking forward to it, I think!
Crazy Africa! Some of my Favorites!
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North Battleford, Saskatchewan, Canada
Salar de Uyuni, Bolivia, November 30, 2017
Uyuni, Bolivia, November 29, 2017
Biking Death Road, Bolivia, November 28, 2017
Puno, Peru to La Paz, Bolivia, November 26, 2017
Puno, Peru, November 25, 2017
Last Day in Cusco, Peru, November 23, 2017
What a Great Day! The Sacred Valley, Peru, Novembe...
Rainbow Mountain, Peru, November 21, 2017
Piles of Rocks, Cusco, Peru, November 20, 2017
Cusco, Peru, November 19, 2017
Colca Canyon to Cusco, Peru, November 17, 2017
Colca Canyon, Peru, November 16, 2017
Peru- A little of this, a little of that!
Arequipa, Peru, November 15, 2017
Puerto Inka, Peru, November 13, 2017
Nazca Lines, Nazca, Peru, November 12, 2017
Nazca, Peru, November 11, 2017
Ballestas Islands and Dune Buggies, Haucachina, Pe...
Lima, Peru, November 9, 2017
Laguna 69, Huaraz, Peru, November 6, 2017
Huaraz, Peru, November 5, 2017
Long Bus Days and Huaraz, Peru, November 4, 2017
Black Turtle Cove, Galápagos Islands and Guayaquil...
Santa Fé and South Plaza Island, Galápagos, Novemb...

redpajama_set_name: RedPajamaCommonCrawl


RadioBOSS is a comprehensive software utility that you can use to broadcast your favorite music. It comes packed with many useful options to suit all preferences.
The interface is clean and fairly intuitive to figure out. Thanks to the Explorer-based folder structure, you can seamlessly navigate directories to locate songs and organize them into playlists.
It is possible to preview music, calculate the playlist start time, edit song metadata (e.g. artist, title, album), and rename files. You can create as many playlists as you want and save them to file.
Furthermore, you can use a search function when dealing with large amounts of data, schedule tracks and playlists for broadcasting (e.g. choose weekdays, repeat, delete task, maximum time to wait in the queue), as well as configure an equalizer.
Other options of RadioBOSS Crack let you view broadcasting statistics, customize colors and fonts, insert tracks from playlists, record voice tracks, manage a music library, generate reports, save profiles, and reconfigure keyboard hotkeys, just to name a few.
The application uses a surprisingly light amount of CPU and RAM, so it does not affect the computer's overall performance. It includes a help file for less experienced users. We have not come across any problems throughout our testing, since the tool did not hang, crash or pop up errors.
All in all, RadioBOSS comes packed with rich features when it comes to making all the necessary adjustments for broadcasting music, and it should please all types of users, regardless of their skill level.
how to use RadioBOSS serial?


We have a PowerEdge R730xd Server and we want to install two PCI SSDs.
Does it matter in which Slots we install the SSDs?? (performance issues...) We want to set up RAID 1.
The RAID controller is not supporting such configuration, so you may try to do a software RAID but then you are not able to boot from it.
The DELL PCI SSDs are special hard drives, they need a additional backplane - but as it is a 730xd there is no space to get this one installed.
So all in all no RAID possible, and installation of DELL PCI SSDs not possible.
It could be that a fusionIO does work but just with a software RAID so w/o boot.


On 27th March 2019, an alarm was received from the remote panic activated by the guard at Paddocks Centre. Armed Response Officers Jonathan and Bandile were dispatched. Upon arrival, Jonathan reported that an armed robbery had taken place at Vodacom Cellucity inside Paddocks centre at about 18:40. Four black males were involved in the robbery. After a camera investigation conducted by Jonathan at Paddocks centre security, it was determined that the suspects entered the shop with a black sling bag and fled the centre via the basement parking area. After the incident was reported, our control undertook a camera investigation and found the following. At about 18:34, a silver/ grey BMW registration number CF 53XXXX stopped at the back of Paddocks and one of the suspects exited the right back passenger door and proceeded on foot around the circle toward the paddock entrance in Grand National Boulevard. The vehicle proceeds down Bridle Way towards the back entrance to Paddocks. The vehicle is seen again leaving the area, past the circle via Bridal way. Undisclosed amount of goods were stolen. SAPS were notified and arrived on scene. Due to this being an ongoing investigation, no further information can be divulged.
Is the suspicious vehicle in fact an Uber?


A monochrome work by Brinda Miller features her signature geometric forms, inspired by architectural elements. Then, there is a sculpture by Arzan Khambatta, with a play of texture, and light and shade, vying for attention. Also, interesting is Paresh Maity's artwork, with its explosion of colour and a profusion of expressive eyes splashed across. These are just some of the works that form part of Breaking Barriers, an exhibition featuring unique horse sculptures by 30 artists such as Miller, Khambatta, Maity, Sujata Bajaj, Jayasri Burman, Seema Kohli, Manu and Madhvi Parekh, Anu Malhotra, and Rithika Merchant. The proceeds from the show will go towards two charities—Khelshala and Passages.
Breaking Barriers is yet another example of not-for-profit organisations commissioning animal sculptures for a good cause. In the recent past, one has seen the Elephant Family, dedicated to protecting the endangered Asian elephant, get artists and designers to create unique works for the Elephant Parade. ARTiger also commissioned 50 artists such as Mithu Sen to work on life-size fibreglass royal Bengal tigers. Here too, the idea is to aid two philanthropic organisations, which serve diverse objectives but are united in their love for art and in their intention to make a difference. For instance, Khelshala, led by the inspiring Satinder Bajwa, former head coach at Harvard University, provides sports, yoga, nutrition to children living on the streets. The idea is also to democratise sports such as squash and tennis.
Then there is Passages, set up by Tarana Khubchandani, who is also the director of Gallery Art and Soul. She used to be a practicing dentist and oral surgeon, when her journey changed course after being diagnosed with breast cancer in 1999. "Soon after, I narrowed the focus of my NGO from empowering women to medical issues to those suffering from breast cancer," she says. Having been treated in the US, she noticed a difference in emotional counselling and imparting of information between the West and back home. "When I came back, I felt a need to share my experience. But I had no means of raising funds. That's when I thought of reaching out to the art community and received an overwhelming response," says Khubchandani, who did her first fundraiser in 2003. With the passing years, the scope of Passages has been evolving—growing from counselling, workshops and publishing of literature to financially aiding chemotherapy sessions and medicines.
This year, Khubchandani wants to add community screening, using an FDA-approved handheld detection device, in her gamut of activities. "It is not meant to replace mammography or visits to the doctor, but is an additional detection tool," she says. "In certain socioeconomic demographics, women visit the doctor only when an urgent need arises. Also, the breast cancer age in India has dropped by a decade. At that age, women are not getting mammography done. So, I thought of starting community screenings with this device," she says. But at five lakh a machine, it is an expensive proposition—which is why she hopes to raise funds through the exhibition to kick start the process.
The works in the show have been designed and produced by Khambatta, with each sculpture painted by leading artists. Starting at 2 lakhs to 3.5 lakhs for a two-and-a-half feet tall sculpture, these offer affordable choices to aspiring collectors. "We don't want to exploit anyone. Hence, we have taken care of the entire production process for the artists," says Khubchandani. The showstopper, of sorts, is an eight feet sculpture by Sujata Bajaj, who came to Mumbai from Paris for ten days, and made the gallery her studio. "She worked day and night, and was also joined by her daughter, Helena Bajaj Larsen. The two have never worked together, so this was a special occasion. Then, there are Manu and Madhvi Parekh—such senior artists living in Delhi—who still found time for the show," says Khubchandani. Scroll ahead to look at some of the showcased works.


text:
Doinb right where he wants to be as worlds final looms
Doinb right where he wants to be as League of Legends World Championship final looms
FunPlus Phoenix mid laner Kim "Doinb" Tae-sang, left, and G2 Esports mid laner Rasmus "Caps" Winther share a smile during a standoff at the League of Legends World Championship semifinals on Sunday at Palacio Vistalegre in Madrid. Photo by Colin Young-Wolff/Provided by Riot Games
Emily RandESPN
MADRID - The Palacio Vistalegre Arena echoed with cheers for Fnatic. They reverberated through the old bullfighting ring, creating an unintentional call-and-response with a slight sound delay, so loud that they could be heard through the players' supposedly soundproof headphones.
"Fa-na-tic!"
Only one game stood between Fnatic's opponents, League of Legends Pro League champions FunPlus Phoenix, and a League of Legends World Championship semifinal berth. On Summoner's Rift, all five members of Fnatic converged for an early ambush of FunPlus bot laner Lin "Lwx" Wei-Xiang. Fnatic support Zdravets "Hylissang" Iliev Galabov threw out Pyke's bone skewer and narrowly missed his target.
League of Legends World Championship final -- How to watch and what you need to know
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G2 Esports vs. SK Telecom T1 was a semifinal to remember
Lwx escaped, and Fnatic's Level 1 game plan was foiled. The crowd let out a collective sigh at what could have been.
A smaller cheer rose up in the crowd for FunPlus Phoenix. Led by Li "Umi" Youzi, the wife of FunPlus mid laner Kim "Doinb" Tae-sang, it was the traditional cheer heard before every LoL Pro League match: an intentional call and response of "FunPlus!" "加油 [jia you]!" It was quickly drowned out by the European home crowd, but it was there, a small, fiercely loyal island in a sea of Fnatic faithful.
Nearly 36 minutes after the opening cheers, Umi walked up the center aisle, carrying a large FunPlus Phoenix flag behind her like a cape. She led a group of FunPlus fans to the stage, where her husband and his team bowed to the crowd. Fans carried banners with Doinb's face on it.
"How on Earth does anyone stop Doinb?" English-language caster Trevor "Quickshot" Henry asked the analyst desk. Moments later, Doinb was asked by the broadcast how it felt to become a worlds semifinalist.
"It's about proving myself," Doinb said, addressing the FunPlus fans gathered at the edge of the stage. "Before this, I've never been to worlds, and I've always doubted if it was because I wasn't good enough. But this proves that I am actually good enough to make it here at worlds."
A week later, Doinb and FunPlus took out the reigning world champions, Invictus Gaming, in the semifinals. Doinb was now a worlds finalist.
Finally, the path he'd chosen had led him to where he wanted to be.
Choice is a luxury that frequently eludes League of Legends professionals.
The ability to have a definitive say in where one decides to play and with whom is often reserved for legacy players like SK Telecom T1's Lee "Faker" Sang-hyeok, who have proven their value countless times throughout years of stunning success.
Doinb entered professional competition at a volatile time in the League of Legends scene: the 2014-15 Korean Exodus, a period when many South Korean professional players left the country and its premier league, League Champions Korea, for other regions. China was a popular destination at the time, and that option was also extended to Doinb, a less-seasoned upstart at the time, as well.
The then-18-year-old was known only for his solo queue exploits as a streamer, but he received offers from both South Korean and Chinese teams. Doinb tried out with various South Korean teams for nearly a month, but didn't feel like any of them were a good fit.
"At the same time, my father really supported me to go to China and explore all of my options because all of the Samsung White guys were going over," Doinb said. Samsung Galaxy White had just won the 2014 League of Legends World Championship. All five of the team's players left South Korea for the LPL that offseason.
"At the time I was just a streamer, a high-elo streamer, and there were a lot of LPL teams that told me their conditions for me to join."
FunPlus mid laner Kim "Doinb" Tae-sang, center front, celebrates with his teammates following their League of Legends World Championship semifinal victory over Invictus Gaming on Saturday at Palacio Vistalegre in Madrid. Photo by Colin Young-Wolff/Provided by Riot Games
Doinb had a wealth of options. In the end, he chose the Qiao Gu Reapers, a Chinese organization that was part of the developmental league.
"I felt like they were the best even though they were only playing in the Challenger league," Doinb said. "I had never played professionally before, so I wanted to do it from the ground up and prove slowly how good I actually was."
Of the choices presented to Doinb at the time, Qiao Gu was one of the more interesting setups. The roster included former Xenics Storm and CJ Entus jungler Baek "Swift" Da-hoon, and the experienced bot lane of Yu "TnT" Rui (also known as Happy) and Zhang "TcT" Hong-Wei (also known as Mor).
Doinb did not speak Mandarin. Up until he joined Qiao Gu, he had only ever lived with his parents. But the culture shock and language barrier didn't stop the mid laner from shining.
Qiao Gu not only were promoted from China's developmental league to the LPL but made it to the LPL finals that summer and were one game away from beating LGD Gaming to claim the LPL summer title. In his first year as a pro, Doinb had vastly exceeded expectations.
He sighed somewhat dramatically as he thought about his first LPL split. It wasn't due to regret but embarrassment, as if he was one moment away from facepalming at his previous naïveté.
"I was really surprised. I thought to myself, 'Am I really that good?'" he said, laughing. "And I felt like my ego was pretty inflated because I was a complete random, and my top laner, jungler, AD carry and support, they had all played professionally before.
"People used to say that all QG was missing was actually a mid laner. I still think I performed pretty well and I kept asking myself, 'Is being pro really that easy?' So I felt that my ego ended up a bit inflated."
Careers can be made and dismantled from singular plays, crystalizing the perception of a player among fans, analysts and even teams' coaching and scouting staff in an instant.
In China's LPL, players are subject to more scrutiny than any other league. The size of the playerbase and fanbase dwarfs all other regions, translating into more fan support but also ceaseless vitriol at times. Former LPL pros have cited the cons that come with such a bright spotlight as reasons for retiring, among more standard causes such as physical injury and ageing out of the game or the exhausting lifestyle it requires.
Self-doubt creeps around every corner in the League of Legends professional scene. It sinks in more deeply when aided by negative public perception. The ability to continue playing, whether it comes from mechanical ability, mental fortitude or innate ambition, is a privilege.
Doinb understands this well. In September 2018, he became inactive on his team, Rogue Warriors, citing health issues. A month later, he announced his retirement.
"For a professional player, it's always a blessing to be able to play," he said. "A lot of players don't get that chance: Either they're just not good enough, or they start to go downhill, or they get old, and no one wants to pick them up anymore, but it was different for me. There were still a lot of teams that believed in me and that wanted me to play for them, so that makes me feel quite happy."
There was a soft undertone to his words, although they were said with the same cheery tone that he uses onstage. Doinb, it seems, is always on. For years, fans and detractors said that this was an act and that Doinb had created a character for streams, press interviews and the LPL stage.
They called him enigmatic and mysterious and wondered who the real Doinb was.
The Doinb that celebrated numerous victories by jumping up from his seat, arms windmilling uncontrollably and sending his chair careening into FunPlus jungler Gao "Tian" Tian-Liang is real. So is the Doinb who locked in Maokai mid against Team WE on purpose. And the Doinb that proposed to Umi at a FunPlus event? He's real, too.
FunPlus Phoenix mid laner Kim "Doinb" Tae-sang, left, talks to his wife, Li "Umi" Youzi, following FunPlus's victory over Invictus Gaming at the League of Legends World Championship semifinal on Saturday at Palacio Vistalegre in Madrid. Photo by Michal Konkol/Provided by Riot Games
Doinb plays League of Legends with a nearly unmatched joy and an understanding of what a privilege it is to be on the stage, whether domestically or in Sunday's final. He knows how valuable his second chance after a premature retirement is.
"Originally I was certain that I was going to retire," Doinb said. "In the trading phase, a lot of people came to Rogue Warriors and asked if I was going to be traded, but I actually told my team that I didn't wish to be traded, that I was going to retire because my body wasn't feeling well. That was the main reason why I wanted to step down.
"I also felt like I had been playing for so many years and I didn't have a good result behind me. I started to doubt myself. Maybe I just wasn't able to get a good result. Maybe this was enough, and I should just leave the scene."
But with the impending departure of veteran Chinese mid laner Yu "Cool" Jia-Jun, FunPlus Phoenix desperately wanted to bring on Doinb. The team courted him that fall, even after Doinb had stated his intentions to retire and stream in China. Members of FunPlus management messaged Doinb daily, ensuring him that they would be strict and disciplined in running the team, going as far as to outline exactly what Doinb's daily life would look like should he join FunPlus Phoenix.
On Dec. 14, 2018, the LPL team Rogue Warriors announced that they had agreed to respect Doinb's wishes and part ways. That same day, FunPlus Phoenix announced that Doinb had signed as the team's new mid laner.
Doinb's teams are known for playing a similar style, regardless of the other players on the lineup, due to Doinb's unique laning style. He will forgo minion waves to push as quickly as possible and then roam to the top lane or bottom lane, helping his teammates. Doinb's legacy as an oddball mid began back on Qiao Gu when his team faced off against Team WE in the Demacia Cup and won. In the third game, Doinb played Maokai mid in what became affectionately known by Doinb fans as his "Juggertree" game.
The rumor was that it was due to a miscommunication error, but Doinb asserted that Qiao Gu had practiced it before the tournament.
"When I was a random, I used to play every position," Doinb said. "I felt like you could always take whatever you wanted mid lane. In scrims we tried it out a couple of times, and it was quite effective. Maokai at the time was a very tanky champion. It was 2015, and people were bringing a lot of different champions into the mid lane like Sion or Cho'Gath in that meta, but I felt like Maokai was the one that suited me the most."
Doinb's unpredictable playstyle only grew through the years due to his insistence on taking tanky bruisers to the mid lane or building protective items like Abyssal Mask, Iceborn Gauntlet and Righteous Glory on mages. He brushed off criticism as it came, saying that he will always be a player who likes to initiate and help his side lanes.
On FunPlus, Doinb has found his true home, with an assortment of players that communicate well together and one of the most formidable jungle-support duos in the LPL in Tian and Liu "Crisp" Qing-Song. His teammates were another reason that he chose FunPlus over retirement.
"On FPX, it feels like we're old friends," Doinb said. "Everyone has known each other for a long time, and we don't have any communication issues. We know each other's personalities well, so if you listen to our mic checks, we don't actually say a lot during teamfights because everyone knows what to do. I think that's really great."
Kim "Doinb" Tae-sang is on to his first League of Legends World Championship final after leading FunPlus Phoenix past Fnatic and Invictus Gaming during the knockout stage. Doinb and FunPlus will face G2 Esports on Sunday in Paris. Photo by Colin Young-Wolff/Provided by Riot Games
Other players on FunPlus have echoed these sentiments of team camaraderie and cohesion.
"My teammates are good," FunPlus top laner Kim "GimGoon" Han-saem told Chinese media outlet PentaQ as the reason why FunPlus qualified for worlds. "Top lane is rather dependent on your teammates. Sometimes, no matter how well you play, it just doesn't matter. I used to put a lot of pressure on myself to lead my team to victory; if I couldn't carry, then the game was pretty much lost. Now it's changed. I no longer have to lead the team. Instead, they carry me, and I calmly focus on playing my best."
At this world championship, Doinb's mid lane skills, or perceived lack thereof, have become one of the larger tournament debates in the League of Legends community. The argument has been boiled down to its essence as a clash of mechanical skill, intelligence and game sense.
Former teammates, like SK Telecom T1 jungler Kim "Clid" Tae-min, say the mental side of the game makes those arguments about Doinb irrelevant.
"I didn't show my own skills that well at Worlds, I was pretty nervous," Clid said after his team's semifinal loss to G2 Esports. "But Doinb's a very outstanding player. He isn't nervous at all, even in this kind of major world tournament. I believe he'll definitely show a good appearance in finals."
His opponents also acknowledge that the willingness to just go for it, meta be damned, is what makes Doinb so dangerous.
"Doinb is a really strong mid laner," G2 Esports mid laner Rasmus "Caps" Winther, and Doinb's upcoming finals lane opponent, said. "I feel like me and Doinb are maybe just more crazy? We are not as solid in a way, but we are just more crazy and think more out of the box and doing crazy things to bring us back in the game or to get a lead. That's why I'm pretty excited to play against FPX."
Doinb, in typical fashion, is simply happy to be part of the mid lane discussion after all these years. This is the playstyle that he chose for himself and genuinely believes it gives his teams the best chance to win.
"I think it really depends on the player, but I would say I'm an above-average mid laner," Doinb said. "A lot of mid laners, they don't get to roam because they can't leave the lane. You need to be at least 50-50 in the lane in order to have a chance to roam. I think roaming is great.
"Before worlds, I read all of the evaluations, and I think they're alright. I'm actually quite happy. I think I've kept a pretty good condition throughout multiple years, so people have grown to know me, and I'm proud about it."
Many people will say that FunPlus Phoenix and Doinb's appearance in the final was predictable -- that they were China's first-seeded team, so naturally they would have a good chance to make it to Paris. But the world championship isn't always kind to its first seeds, especially those from China. The LPL faithful will say that of the three Chinese teams, FunPlus was actually the most predictable in playstyle and possibly the least likely to make it.
On Sunday, despite those perceptions, Doinb and FunPlus will face off against G2 Esports in the worlds final.
"He said he'd take me to Paris," Umi's wrote on Twitter after Doinb and FunPlus beat iG and qualified.
She also shared a conversation that the two had on Weibo about traveling to Europe.
"How about you bring me to Paris this year?" Umi had written.
"Haha, okay," Doinb wrote back. "My form has been really good recently. 'ㅅ' This time I'll take you to Europe, my darling."
A friend comforts Li "Umi" Youzi, front, following FunPlus Phoenix's victory at the League of Legends World Championship semifinal on Saturday at Palacio Vistalegre in Madrid. Umi is married to FunPlus mid laner Kim "Doinb" Tae-sang. Photo by Michal Konkol/Provided by Riot Games
The spotlight that has followed Doinb throughout this world championship has, by extension, followed Umi, who is a former Dungeon Fighter Online caster. Doinb has always had an effervescent quality that bubbles up as he speaks. He giggled as he shared the story of their first meeting. It was like something out of a romantic comedy set in a Shanghai café. His grin was wider than ever.
"The first time I saw her, I thought she was incredibly beautiful, but I didn't speak any Chinese," Doinb said. "I felt pretty awkward, so I showed her my phone. By chance she was also into esports. She was a caster for DnF, and she was in the scene as well, so it just kind of happened after that."
Sharing their relationship so openly on the world's largest League of Legends stage has allowed Doinb to showcase his personality side-by-side with his unconventional playstyle. On Sunday, he'll get one more chance to do so.
A series of promotional photographs for the upcoming finals were taken after the second semifinal: G2's 3-1 victory over SK Telecom T1. There were the usual stare downs, but both teams couldn't help but laugh, especially during the individual position matchups. Doinb and Caps shared knowing smiles as they positioned themselves back-to-back has become the go-to shot for Sunday's match.
As always, Doinb's charisma leapt off the screen. It could have been a forced, awkward moment, but Doinb chose to smile.


University of Bristol - Historical Photographs of China reference number: He02-025. Photo from an album (UoB reference He01) kept in the School of Oriental and African Studies Archives, London (SOAS reference PP MS 82/15).
Aigun (Taheiho) April 1923 - October 1925. Aigun Commissioner's House at Taheiho.


How can you turn back time? It's a redemptive question we've all entertained. We as humans struggle to grasp the brevity of our time on this earth. Just as a highway offers mile markers to track our progress to the next landmark so our years track our progress and movement throughout life. They remind us we are going somewhere.
As children we sat impatiently in the backseat repeatedly questioning the our parents,"Are we there yet?". We too question God about our progress and where He is taking us. Remember as children straining to see over the seat or climbing on our knees to see out the window as others yelled, "Wow! Did you see that!" only to be disappointed because we were simply too late. Life can bring moments that leave us feeling like we have just missed the biggest moment or opportunity of our lives.
Regret is a cruel taunter that enters our minds loudly telling us we can never get back the time we have wasted. During the last eight weeks of recovering from an ATV accident that left me with seven fractured ribs, a partially collapsed my lung, and damaged discs in my neck; I have struggled with these thoughts. I told my husband yesterday that the time since my accident has felt like one long day. My existence looming between the recliner in my living room and our bed. If I am not careful, I will lose the value of these still moments focusing too much on what I think I am missing.
I remember as a young mother in my early twenties still struggling with my own personal desires to pursue a music career. During the few months we lived in Blytheville, Arkansas I entered a nationally televised singing competition in Nashville that was much like what we how know to be "American Idol". Voters cast votes by telephone call and I managed to finish 6th in the finals, but nothing changed. No doors opened and I went back to life as a stay at home mom. I felt life was passing me by and I could do nothing to change my course.
One morning I sat in an especially powerful worship service and God was moving in such a powerful way through the music and ministry of its leaders. I closed my eyes and in my mind and soul I could hear wind blowing. I began to hear the ticking of a clock and could see a book laid open. The wind was blowing its pages before my eyes. I was having what some would call an open vision. In this vision I found myself on a beach beside a vast ocean. My hands were filled with broken pieces that I knew were my dreams. I was desperately looking for a way to fix them, or better yet someone who could piece them all together. I heard the Spirit of God say to me, "Give me your dreams." And again moments later, "Will you trust me with your dreams? Give me your dreams." I reluctantly and carefully laid each precious piece on the sand before the Lord. Suddenly a wave came and washed my dreams into the ocean. I remember screaming, "Why God? Why did you take my dreams? It was all I had? The vision was over and I again heard the wind, the ticking clock, and the pages turning and I wept.
We live in a society of such unrestrained waste. We waste water, food, electricity, and the list goes on and on. In comparison with much of the rest of the world, we live as kings and queens in a land of excess. I will be the first in this group of wasters to stand and say, "I am guilty." I am not a recycler who puts out bins by the side of the road on Thursdays like some of my other neighbors and I'm certain I could do more to leave less of a burden on the world my children will inherit. Although what I am writing today has everything to do with leaving more and wasting less it has much more to do with using valuables that are impossible to recycle or repossess.
I remember the day after I returned from my first medical missions trip in Honduras so clearly. My husband and I set together at one of our favorite local restaurants, Rolandos, to share a meal and discuss my trip. The waitress sat a cold, clear, complimentary glass of water on our table and I felt emotion began to flood my heart. While in Honduras the value of that one glass of water had changed. The value of clean, readily available, drinkable water had escalated exponentially from my experience in a place that was lacking such luxury.
Water in Tegucigalpa, Honduras is precious. In order to provide "upside down foot washing" ,the act of treating children for head lice, water had to be delivered in barrels by truck. Every small bucket poured had great value and purpose. It was inexcusable to waste or play with water in Tegucigalpa, yet where I lived many showered it daily on their lawns to maintain green grasses. We all believed we had more than enough to waste.
This is the same dangerous way in which we "spend" many of our days. We improperly assess their value or falsely believing we have plenty to waste. We pour hours into entertainment, electronics, pleasure, and miss the value of real "face time" and in person connectivity. We all need our own "clear glass on the table" moment. For myself, that most recent moment happened suddenly and without warning when I slammed my ATV into the side of a mountain in Puerto Vallarta, Mexico. In fact, every word I type right now is precious because it is done so with pain as I recover from seven fractured ribs, a partially collapsed lung, and an injured right arm.
I hope you will encourage me, and help keep me on task until I finish my set course. The most valuable thing I have discovered through my accident is that God has encircled me with the most incredible, loving, caring family and friends anyone could every imagine. Thank you all for standing by me when I needed you most.


Updated: March 7, 2019, 4:02 p.m. Excellent medical center that caters to the LGBT community, located in Washington, DC. It's also the premiere transgender care facility in the DC metro area, offering comprehensive services including counseling, medical care, pharmacy, and even legal services for name/gender change and discrimination cases. Highly recommended!


text:
Q: Why is $\sqrt{-i} \neq i\sqrt{i}$? I wanted to figure out the square root of $-i$.
Since $\sqrt{-x} = i\sqrt{x}$,
$\sqrt{-i}$ should equal $i\sqrt {i}$, however, WolframAlpha said it was false.
However, if I do say that $\sqrt{-i} = i\sqrt{i}$, I can replace $\sqrt{i}$ with $\dfrac {1+i} {\sqrt{2}}$, leaving me with $\sqrt{-i} = \dfrac {i(1+i)} {\sqrt{2}}$
Now I distribute, giving me $\sqrt{-i} = \dfrac {i-1} {\sqrt{2}}$
Then I square both sides, giving me $-i = \dfrac {(i-1)(i-1)} {2}$
Then I FOIL, giving me $-i = \dfrac {-2i} {2}$
Then the $2$'s cancel out, leaving $-i = -i$, making $\sqrt {-i} = i\sqrt{i}$ a true statement.

A: Remember that every number (except $0$) has two complex square roots -- and if you choose appropriate square roots then your relation does indeed hold.
In particular, if we take $\sqrt i = \frac{1+i}{\sqrt 2}$ and $\sqrt{-i}=\frac{-1+i}{\sqrt 2}$ (and these are indeed possible square roots of $i$ and $-i$), then you do get $\sqrt{-i}=i\sqrt{i}$.
Wolfram Alpha probably chooses to set $\sqrt{-i}=\frac{1-i}{\sqrt 2}$, in which case you have $\sqrt{-i}=-i\sqrt{i}$ instead.

A: Your assumption that $\sqrt{-x} = i\sqrt{x}$ is incorrect. Suppose $x=-4.$ Then $\sqrt{-x}=\sqrt{4}=2\neq i\sqrt{-4}=i\cdot2i=-2$

A: You are running up against a complication that arises with roots of complex numbers: they are not single-valued, but multi-valued.  If you express the question "what is $ \ \sqrt{-i} \ $ ?" as "what are the roots of the equation $ \ x^2 \ - \ (-i) \ = \ 0 \ ? $ " , there are two solutions. DeMoivre's Theorem tells us that the square-roots of $ \ -i \ = \ \cos(\frac{3 \pi}{2}) \ + \ i \ \sin(\frac{3 \pi}{2}) \ $ are
$$  \cos(\frac{3 \pi}{4}) \ + \ i \  \sin(\frac{3 \pi}{4}) \ = \ \frac{-1 + i}{\sqrt{2}} \ \ \text{and} \ \ \cos(\frac{7 \pi}{4}) \ + \ i \  \sin(\frac{7 \pi}{4}) \ = \ \frac{1 - i}{\sqrt{2}} \ \ . $$
The square-roots of $ \ i \ = \ \cos(\frac{ \pi}{2}) \ + \ i \ \sin(\frac{ \pi}{2}) \ $  are
$$  \cos(\frac{ \pi}{4}) \ + \ i \  \sin(\frac{ \pi}{4}) \ = \ \frac{1 + i}{\sqrt{2}} \ \ \text{and} \ \ \cos(\frac{5 \pi}{4}) \ + \ i \  \sin(\frac{5 \pi}{4}) \ = \ \frac{-1 - i}{\sqrt{2}} \ \ . $$
We can see that if we multiply each of the square-roots of $ \ -i \ $ by $ \ i \ $ , we will get one of the square-roots of $ \ i \ $ , but the correspondence is not as simple as is suggested by the putative equation $ \ \sqrt{-i} \ = \ i \ \sqrt{i} \ $ .
What WolframAlpha appears to do is take as the principal values for these square-roots the ones where the angle (argument) in the complex plane is in the domain of the arctangent function, $ \ -\frac{\pi}{2} \ < \ \theta \ < \ \frac{\pi}{2} \ $ .  When you just look at that, the equation doesn't work.  But further down the pages, when you look at all the square-roots, you see that the locations of the two square-roots of $ \ i \ $ get rotated by $ \ \frac{\pi}{2} \ $ (upon multiplication by $ \ i \ $ ) to give the locations of the two square-roots of $ \ -i \ $ .  So your equation is "wrong" in the sense that the complex square-root function has to be described more carefully than the one defined only for real numbers.

redpajama_set_name: RedPajamaStackExchange


text:
class BrowserView;
class FindBarController;
class FindNotificationDetails;

////////////////////////////////////////////////////////////////////////////////
//
// The FindBarHost implements the container widget for the
// find-in-page functionality. It uses the implementation from
// find_bar_host_aura.cc to draw its content and is responsible for showing,
// hiding, closing, and moving the widget if needed, for example if the widget
// is obscuring the selection results. It also receives notifications about the
// search results and communicates that to the view.
//
// There is one FindBarHost per BrowserView, and its state is updated
// whenever the selected Tab is changed. The FindBarHost is created when
// the BrowserView is attached to the frame's Widget for the first time.
//
////////////////////////////////////////////////////////////////////////////////
class FindBarHost : public DropdownBarHost,
                    public FindBar,
                    public FindBarTesting {
 public:
  explicit FindBarHost(BrowserView* browser_view);
  ~FindBarHost() override;

  // Forwards selected key events to the renderer. This is useful to make sure
  // that arrow keys and PageUp and PageDown result in scrolling, instead of
  // being eaten because the FindBar has focus. Returns true if the keystroke
  // was forwarded, false if not.
  bool MaybeForwardKeyEventToWebpage(const ui::KeyEvent& key_event);

  // FindBar implementation:
  FindBarController* GetFindBarController() const override;
  void SetFindBarController(FindBarController* find_bar_controller) override;
  void Show(bool animate) override;
  void Hide(bool animate) override;
  void SetFocusAndSelection() override;
  void ClearResults(const FindNotificationDetails& results) override;
  void StopAnimation() override;
  void MoveWindowIfNecessary(const gfx::Rect& selection_rect) override;
  void SetFindTextAndSelectedRange(const base::string16& find_text,
                                   const gfx::Range& selected_range) override;
  base::string16 GetFindText() override;
  gfx::Range GetSelectedRange() override;
  void UpdateUIForFindResult(const FindNotificationDetails& result,
                             const base::string16& find_text) override;
  void AudibleAlert() override;
  bool IsFindBarVisible() override;
  void RestoreSavedFocus() override;
  bool HasGlobalFindPasteboard() override;
  void UpdateFindBarForChangedWebContents() override;
  FindBarTesting* GetFindBarTesting() override;

  // Overridden from ui::AcceleratorTarget in DropdownBarHost class:
  bool AcceleratorPressed(const ui::Accelerator& accelerator) override;
  bool CanHandleAccelerators() const override;

  // FindBarTesting implementation:
  bool GetFindBarWindowInfo(gfx::Point* position, bool* fully_visible) override;
  base::string16 GetFindSelectedText() override;
  base::string16 GetMatchCountText() override;
  int GetWidth() override;

  // Overridden from DropdownBarHost:
  // Returns the rectangle representing where to position the find bar. It uses
  // GetDialogBounds and positions itself within that, either to the left (if an
  // InfoBar is present) or to the right (no InfoBar). If
  // |avoid_overlapping_rect| is specified, the return value will be a rectangle
  // located immediately to the left of |avoid_overlapping_rect|, as long as
  // there is enough room for the dialog to draw within the bounds. If not, the
  // dialog position returned will overlap |avoid_overlapping_rect|.
  // Note: |avoid_overlapping_rect| is expected to use coordinates relative to
  // the top of the page area, (it will be converted to coordinates relative to
  // the top of the browser window, when comparing against the dialog
  // coordinates). The returned value is relative to the browser window.
  gfx::Rect GetDialogPosition(gfx::Rect avoid_overlapping_rect) override;
  // Moves the dialog window to the provided location, moves it to top in the
  // z-order (HWND_TOP, not HWND_TOPMOST) and shows the window (if hidden).
  // It then calls UpdateWindowEdges to make sure we don't overwrite the Chrome
  // window border.
  void SetDialogPosition(const gfx::Rect& new_pos) override;

  // Retrieves the boundaries that the find bar widget has to work with
  // within the Chrome frame window. The resulting rectangle will be a
  // rectangle that overlaps the bottom of the Chrome toolbar by one
  // pixel (so we can create the illusion that the dropdown widget is
  // part of the toolbar) and covers the page area, except that we
  // deflate the rect width by subtracting (from both sides) the width
  // of the toolbar and some extra pixels to account for the width of
  // the Chrome window borders. |bounds| is relative to the browser
  // window. If the function fails to determine the browser
  // window/client area rectangle or the rectangle for the page area
  // then |bounds| will be an empty rectangle.
  void GetWidgetBounds(gfx::Rect* bounds) override;

  // Additional accelerator handling (on top of what DropDownBarHost does).
  void RegisterAccelerators() override;
  void UnregisterAccelerators() override;

 protected:
  // Overridden from DropdownBarHost:
  void OnVisibilityChanged() override;

 private:
  // Allows implementation to tweak widget position.
  void GetWidgetPositionNative(gfx::Rect* avoid_overlapping_rect);

  // Returns the FindBarView.
  FindBarView* find_bar_view() { return static_cast<FindBarView*>(view()); }

  // A pointer back to the owning controller.
  FindBarController* find_bar_controller_;

  DISALLOW_COPY_AND_ASSIGN(FindBarHost);
};

#endif  // CHROME_BROWSER_UI_VIEWS_FIND_BAR_HOST_H_

redpajama_set_name: RedPajamaGithub


OTS-03 Backland figure not included.
This reissue of Brawny will feature small updates on the joints and color as well as a 2nd Edition label on the packaging. Brawny will include the original bonus accessory in the box. Brawny stands 6 inches (15cm) tall in robot mode and transforms into an off road truck.
This figure is made of plastic and features die cast pieces in the crotch, the connection part of hip and two thighs (inside the leg). The figure also features ratchet joints and a rubber coating on the wheels.


text:
Culture Cave: Life At The Other End Of Honolulu's Brain Drain - Honolulu Civil Beat
Culture Cave: Life At The Other End Of Honolulu's Brain Drain
There's an exodus of creatives bound for New York City, again. Here, we compare apples to (pine)apples.
By James Cave / March 2, 2015
Reading time: 15 minutes.
New York City and Honolulu aren't all that different, when you think about it.
For example, New York has an ABC store, an art gallery called the Agora, a Mercury Bar, Marco Polo building, and Turtle Bay. If you go there during any of the three months out of the year when the weather feels Hawaiian, you might get confused about where you are.
Just kidding – I don't know enough about Manhattan yet to understand the deeper similarities between these islands.
But, I will say that last week, my colleagues and I took a work trip to New York to meet the people who run the Huffington Post mothership. We'd all picked a wonderful time to go — mid-February, when Canada reaches down and slaps everyone in the face with its brutal, wintry exhalations.
I saw New Yorkers stop in the crosswalk to congratulate each other on crossing the street, that's how cold it was.
From left, Mark Chittom, Natalie Austin, Mitchell Anicas and Tyler Wolff at Kinfolk in Brooklyn, New York.
James Cave/Civil Beat
On one snowy night, I stepped into a bar called Kinfolk in Brooklyn to order a drink. I'd quickly assumed I'd just been drugged, because standing near the DJ booth looking like he owned the place was none other than Mark Chittom, with Mitchell Anicas, Farley Rossiter, and Timo Lee — former Honolulu DJs, musicians, artists, bar owners, producers, writers or combinations thereof, and nearly 10 other Hawaii artists and expats talking and dancing as if the entirety of 2014 didn't happen and we were still upstairs at Gelareh Khoie's thirtyninehotel dancing to Ross Jackson's Kaleidoscope party.
It wasn't a mirage, but the aftermath of an exodus. Now, back in Honolulu, I wanted to hear why they left, and what, if any, reflections they have about leaving Hawaii behind to join the madding crowd.
Here, Timo, Chittom, and Khoie told me why they answered the beckoning call from the other end of the brain drain (a mode of transportation that I realize now isn't nearly as evil as I once thought it was).
Timo Lee
Timo Lee lived in Hawaii for 14 years, and worked as a DJ, promoter and manager at thirtyninehotel until she and bartender Christian Self opened Bevy in Kakaako in 2013. She relocated to New York about a month ago, and last weekend found an apartment in Prospect Heights. While she plans to split her time between Honolulu and New York, Lee still remains active in Bevy and says she hopes to bring a New York approach to musical trends in Honolulu when she visits and performs throughout the year:
Facebook photo
"I've been wanting to move to New York for many, many years. The first time I came to New York was in 2008, or '09, and I just fell in love with the city. There's just so much happening. It blew my mind. Especially the music scene, because I'm a DJ. I feel more motivated. There's lots of parties; different DJs come to New York and you get to go see them, see what's going on. It's a bigger scene for the stuff I like – house, disco, electronic music. That's one of the main reasons I decided to come: I wanted to feel motivated and challenged.
"In Honolulu, you almost feel like you reach a point where you can't go further anymore. The feeling – Bevy's great and I get to DJ there and stuff, and I really enjoy DJing with the Asylum crew too, but it's limited. I was definitely craving a bigger scene. Honolulu just doesn't have a big audience. I started to feel unmotivated a little bit. I wanted to do more, and further my music career, but in Honolulu, I was getting too comfortable.
"It's been a pretty stressful month and a half, because I've been looking for an apartment, and this city's very fast paced. It's not like Hawaii and laid back. You have to be on the go, go, go, go — you have to make decisions very fast. I'm definitely adjusting to all that. I'm from Taipei, so I miss this type of fast-paced city life.
"I'll still fly back and forth to Honolulu, because I'm still involved with Bevy, and I'll try to avoid the winter here. This year's was really painful! It's getting colder and colder. I love Hawaii — I was born there actually, and will stay involved with Honolulu. I really want to go back. I miss my friends."
Mark Chittom
Mark Chittom wrote the Honolulu Weekly column, "Clubbed To Death," for five years, threw many parties and recurring shows at thirtyninehotel and other clubs throughout Chinatown, and covered and contributed to Chinatown's transition, what he calls its "shift from crackville to nascent artist community." Chittom moved to New York in 2009, returned briefly in 2011, and moved back to New York permanently in 2014:
"I moved out here for the first time in 2009 and it was mostly because I felt like, as a DJ, there's really nowhere else for me to go. I loved it at thirtynine, but I just felt like it was getting a little repetitive for me. I just wanted to go where it was bigger – it's like, if you want to be a big wave surfer, you go to Hawaii. If you want to be a DJ, you go to New York or LA, or someplace like that. You go to a place where it's the cultural center of that thing. That's pretty much why I left.
"For Honolulu to be what I'd need it to be, it would just have to be more. But Honolulu's not going to get bigger. The people who are doing it – I think a lot of them are doing great. But, with the Weekly closing, and thirtynine closing — for a long time I felt that, if it weren't for thirtyninehotel, I don't know if I would have been able to live there. Thirtynine was a community that I could be a part of, where we all had a common purpose of just making it happen. So it was cool like that, but you had to work so hard for such little reward. I'm not even talking about money, I'm talking about people showing up and having a good time. It was really difficult. And so it got demoralizing after a while.
"There's a really cool community of Hawaii people up here who are doing things, people who are really active in the disco community, and it's all from stuff they learned in Chinatown." — Mark Chittom
"Let's take, for example, an official arts community like the Honolulu Museum of Art. They're only going to have a new big show every six months or so, and you can go to it and then you have to wait another six months. Things happen so slowly in Hawaii that it's hard to keep your attention focused on it, whereas in New York, it's like you're never going to be able to do everything that's new, much less see all the established things. There's just so much more. To me, that level of stimulation is what I prefer. I certainly think Pow Wow is great. The projects that Wei Fang does with the Agora space and Interisland Terminal is all really awesome. And obviously the Hawaii International Film Festival is great. But to me, there's just never quite enough going on to keep my level of stimulation high enough to have an impact on my life.
"It can be really cold in New York. I'm not crazy about the weather today — I'm literally counting the days to spring. And if spring is still cold, I don't know what I'm going to do! But, you deal with it. I'd rather deal with harsh weather than deal with a lack of stimulation. It's weird. I don't want to disparage Hawaii, because it's very stimulating in a lot of ways, but in the particular things I'm interested in, it stopped doing it for me after awhile.
"Another reason I moved: There's a really cool community of Hawaii people up here who are doing things, people who are really active in the disco community, and it's all from stuff they learned in Chinatown. These are original people around when Chinatown made this shift from crackville to nascent artist community. It's not like we're just up here trying to make our way in the big city. It's like we have a community of people who speak the same shorthand; we go way back. And now we're finding new people who want to be a part of our community. It's really good and that makes living here a lot easier and a lot more rewarding. In some ways, it's like you still get to have a lot of what's cool about Hawaii, which is the people, and there's a bunch of them up here. That makes it a lot better."
Gelareh Khoie
Gelareh Khoie opened thirtyninehotel in 2004 to give artists, DJs, bands, and creative bartenders a place to gather, work, create and party. An artist herself, she featured large pieces by herself and many contemporary artists on the evolving walls of her club, but after awhile, the nightlife scene took its toll. Whereas thirtyninehotel was a centerpiece in the art community for 10 years, a dispute between Khoie and her landlord, combined with constant battles with what Khoie considers systemic, prohibitive problems in city government, she closed the club in 2014 and moved to Red Hook in upstate New York to "get away from all things Hawaii." In a few months, she'll move to Berlin to start her next act: open a mixed use gallery and studio where everything is free, and she can focus on her art again:
Courtesy Gelareh Khoie
"I just needed some time and space to be completely alone. I moved to Hawaii from San Francisco, so I already did that whole thing prior to coming to Hawaii. When I arrived in Hawaii, creating that similar dynamic vibe became my obsession, really. And I think that I obviously did that, I helped to manifest that type of San Francisco/New York kind of vibe. I don't know how to explain it, just that there would be options in terms of art and music, and that creativity is thriving. That's what people look for when they leave Hawaii. I moved upstate, because I feel like there was so much pressure on me for such a long period of time. And when I left Hawaii, I didn't feel like I needed to go and access more things. I didn't really feel like I had missed out on anything – I needed a little bit of peace and quiet.
"The pressures came in the last couple of years. Specifically, my landlady was pressuring me a lot about the permits, and I'm not a businessperson. I never really was. I'm an artist. At thirtynine, even though it was really popular, I was always in the red. She was always breathing down my neck about that, being aggressive with me. Her energy was slowly eating away at me, at my ability to maintain hope and maintain joy. The kind of things you need when you run a space like thirtynine, which was all about giving love to the community through art and music. But I slowly felt that love drain out of me. I don't think she really realized that's how it was, but I'm not a tough skinned businesswoman, and I don't respond to that kind of energy. Then after nine years of business, the Department of Planning and Permitting wanted me to spend $80,000 to put in a sprinkler system. So you know, oh my God, to be treated in this way after 10 years of business in transforming a derelict neighborhood into a thriving economic center, it broke my heart. And I wanted to get as far away as possible from everything Hawaii.
"The move has been good for me! I quit drinking and smoking three weeks after I got here. I've become vegetarian and meditate. I've completely said goodbye to the party life, and perpetuating that level of love of disco just hasn't been important to me. Mark Chittom and Timo, they're still really enamored of it, and still wanting to perpetuate the thirtynine thing in New York City, which is great. The party will always continue to live. I needed some space from all that.
"Look at what happened in Chinatown: they're not even closing the streets anymore for First Fridays. That was a decade-long run, and there was no support from the government." — Gelareh Khoie
"I'm moving to Berlin in a couple of months, opening a new thirtynine there. It'll be a really minimal version of it, and I'll work on a new method, where everything is free. It'll be a DJ space, but no bar. I think there might be free coffee and maybe people can bring their own beer. It's just going to be art and music, and I'm going to do it myself, probably live in the back. I'm really interested in experimenting with this idea, trying to get out of the financial rat race, experiment with this sort of free economy. I'm going to see if the universe will provide, and I'm calling it 39berlin.
"Thirty nine (the original address of the Chinatown location) has just become a significant number in my life and now I have a glimmer of inspiration again. I think that, I don't know how to say this without offending people, but I would love to interact with civilized people who just acknowledge reality. Hawaii's a beautiful and amazing place, because you can just run on 60 percent ambition and be perfectly fine. You don't have to really try that hard and you can dream your life away. And that's totally fine. But, particularly for artists, that kind of laissez faire attitude can become stifling and boring. And when you do try, nobody really comprehends. You start to think that you don't need to try that hard.
"OK, you know how thirtynine was a place where artists and writers and poets and musicians used to hang out and it was like a cool hive where people could interact with one another and bounce ideas — that's how it was for a while. Chinatown grew to have some really quite lovely potential. But that died at one point. It was stifled. A little mediocre status quo jumped on the bandwagon and the raw creative energy dissipated. Because, in Hawaii, there's no need to work hard, and maybe there's no reward for the intellectuals. There's no ultimate reward for going out of your way and trying to do something a little bit above average. So you just give up.
"It's a low ceiling, but we accept it and try anyway because we love living there — it is lovely to live there. You get lulled into a sense that it's great, and then one day you hit this wall. You say, OK, I can't take another moment. You wake up and go, oh my God, my whole life can pass me by if I don't make a move now. It's too bad, because I think there's a lot of things that the government, in concert with the various landowners, could do to support and encourage intellectual energy and community.
"Look at what happened in Chinatown: they're not even closing the streets anymore for First Fridays. That was a decade-long run, and there was no support from the government. They did nothing but hound anybody, as far as I know. They wouldn't spend any money beautifying, so it stayed crappy. Visionless.
"I love Hawaii, and I think it will always be a part of me and have a special place in my heart. For the actual place and the land and the people, I have nothing but love. But for the trolls running the government, I have only contempt."
These statements were edited for space considerations from telephone interviews.
James Cave
James Cave is an award-winning arts and entertainment writer, and a former associate editor of HuffPost Hawaii.
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During the event, AWSforbusiness.com met up with Varinder from Saviynt.
Saviynt is a leading provider of Cloud Security and Identity Governance solutions. Saviynt enables enterprises to secure applications, data and infrastructure in a single platform for Cloud (Office 365, AWS, Salesforce, Workday) and Enterprise (SAP, Oracle EBS).
Saviynt is pioneering IGA 2.0 by integrating advanced risk analytics and intelligence with fine-grained privilege management.


Hello Lekki! I have asked my professional colleagues the same question about other forms of social media. There is no one right answer. Some folks maintain two accounts. I personally think it is too much trouble to maintain two accounts. I think the posts about Firework, cookies, and genes give us a holistic view of you. Your academic colleagues will know that there is more to you than genes and lipids and your personal friends will get some insight on what you really do for a living. I love hearing about your work, Firework, nutrition, your fitness journey, and even the Tough Mudder. I like option 3 the best but you should do what is easiest!
Well, it's a work blog. The value of the two blogs might be different. You need to find out what UT wants you to do with it. Do they want you to use it to promote you, or the university? This one is obviously about you, and your life is made up of a lot of different things: Firework, school, etc. The scope for the UT blog might need to be more restrictive.
I think you could restrict the UT blog to UT stuff, and include a link here. Or copy the UT blog articles here, if it won't alienate your cookie recipe readers too much. For a successful blog, you need to consider the niche you're serving and protecting the value added of each blog. Otherwise, you try to be everything to everybody (like Facebook).
But they're your blogs. Go with what you feel.
Managing two blogs on wordpress under the same log-in is actually really simple. I have a professional one which is not at all linked to my personal one. For my purposes and profession, I wanted them separate, but it would be really easy to keep the two separate, but still have them easily linked.
On WordPress, I think Widgets would be the best way to get what you are wanting out of both blogs, but that is my personal opinion. Just go look at the list of widgets available! It completely astounded me when I started rearranging my blog.
You can post a permanent link to the professional blog here (and vise versa) and add your other blog to a blog roll so it shows up when you post something new. People who want both will still realize it is the same person posting but they can access the different facets of your life more succinctly this way.
Two seperate blogs also allows you to make one blog private for a while if you need to without removing all your other writings.
You can also add an archives widget that will help readers and yourself navigate older posts better.
I forgot to say there is also a widget for adding a follow button to a blog.
Thanks so much for all the feedback. I think I wasn't clear: The UT blog (if I run with it) will be UT only. I am happy for people to google me and find out about my personal life (and do write mindfully knowing about that) but I don't want it explicitly posted on my UT blog. So, I would not add a widget or a blogroll on my work blog for this blog.
So, I guess my question was more: if I have to do have the UT blog, do I bother to copy and paste the UT stuff over here and if so how (or do I remove my academia posts from this blog entirely?)? Seeing as – to my surprise – many of my non academic friends actually enjoy the academic posts, it seems to a shame for them to disappear entirely from here: and Tony and Gabe seem to agree. Leave UT as UT only: but keep the info here too.
The question is the best way to do that: kind of like a 2-way mirror. Links vs copy and paste vs blogroll. Peaches: my logins are different for the 2 blogs (One was set up by UT)… I am wondering if wordpress can 'meld' them for me? But I think Peaches has hit the nail on the head by saying that basically: the solution is out there. I just need to play around with what I am comfortable with.
Hmmm… I have not had to do this so I am not sure aside from the old fashion copy-paste. Bleah… Wes is funny!