text:
Drive Car of the Year 2021 revealed: Behind the scenes of Australia's biggest car awards
By Stuart Marsh • Senior Producer
Blistering heat. Driving rain. Thousands of dollars' worth of coffee and Gatorade. More than $7 million worth of vehicles and just as many opinions.
Finding the best car in the country is no mean feat.
Now in its fifteenth year, Drive's Car of the Year award is a logistical exercise more akin to herding cats (and keeping them cool) than a leisurely drive in the countryside.
Awarded to the family-friendly KIA Sorento – which brought to the table surprising driving dynamics, segment-leading value and enough features to distract even the most iPad-beholden kids – the 2021 edition proved to be one of the most brutal on the judges.
Almost 90 cars, worth more than $7 million. To say the awards were extensive is an understatement. (Drive)
A full list of this year's winners can be found below.
After whittling down a bowser-bursting selection of 600 vehicles, the dedicated team of seven Drive judges took to a week at Luddenham Raceway in Sydney to have the cream of the crop battle it out.
Despite having the track to themselves, it wasn't a case of fanging each car around the circuit and giving the gold medallion to the quickest.
Each vehicle was marked against a set of criteria that are most relevant to the consumer including driver technology, comfort, safety, ongoing running costs, plus all the fun stuff including performance and handling.
The unsung heroes of the video team pushing the gear - and their bodies - to the limit. (Drive)
As Drive Managing Editor and judge Trent Nikolic tells 9News.com.au, while a German-bred rocket that slots a 0-100 time of 2.2 seconds may be the frontrunner to tickle any petrolhead's fancy, you're going to struggle to fit a baby seat in it.
"The only thing I tell the judges is to keep in mind what moves the game forward the most, for the most Australian buyers," Nikolic says.
"A Porsche 911 Turbo S? Awesome car. But at half a million dollars, how many Australians are going yeah I'll have one of them to run the kids to school?"
Every car was taken through a slalom, an 80-0 brake test and half a lap as part of testing. (Drive)
Following almost 12 months of testing, the team assembled 89 segment-leading vehicles to try and split hairs and scratchy plastics to find the overall winner.
In total there were $7.1 million vehicles in the fight, with the cheapest being a plucky Kia Picanto at $18,240 and the most expensive being a $484,880 Ferrari.
If you parked each of the cars end-to-end, you'd just about fill up an athletics track and the total weight of the vehicles tipped the scales at more than 144 tonnes.
The cars were ready, the track was clean and all the team needed was the forecast to play ball.
Pieces to camera in 40 degree heat on a racetrack are easier said than done. (Drive)
"We had every single weather condition you can possibly imagine. It went from pouring rain and wind to forty-degree heat," said Drive's Director of Content James Ward.
"We had the problem on the last couple of days where the Drive numberplates on the front of the cars for the video shoots was simply melting off."
"We had people go down with heatstroke. And awful hamburgers," interjected Nikolic.
Cars that had been sitting on track waiting for their review boasted internal temperatures of more than 70 degrees.
"We were all pretty taxed by the end of it," added Ward.
The judges debating over the merits of people movers ... and dodgy hamburgers. (Drive)
Despite the trials and tribulations of driving Australia's best cars – and taking unlikely track heroes such as minivans through slaloms – the team came through after non-stop 12-hour days to award their winners.
As it turned out, fastest is not always greatest.
"It's really interesting to do those tests like the slalom with cars from all segments. You don't always come away and say the Ferrari is the most fun because it's really stupidly fast," said Nikolic.
"It is stupidly fast but it's also intimidating for a lot of people and you can't access that last bit of the performance envelope like you can in something like a Ford Puma."
Ladies and Gentlemen, your winner: the Kia Sorento. (Drive)
Other diamonds in the rough also shone through despite not boasting track-ready capability.
"The car that surprised us the most and was right up there in the final standings was the KIA Carnival, a people mover," said Ward.
"If you had said to us this time last year that one of the frontrunners for Car of The Year would be a van, we would have laughed.
"The winner could have been a dual-cab ute, it could have been a hatchback, it could've been an SUV."
Black shirts, black cars and a black racetrack - the perfect recipe for heatstroke. (Drive)
After a litre of sunscreen, six cans of fly spray and several heated debates – pitched as "banter" between the crew – the winners were found.
"At that point when you're trying to get to the winner you're looking at knee room in the second row, USB charging ports or which one has better graphics," says Nikolic.
"We had to get down to that level because in some categories, everywhere else you just could not split the contenders."
Every car was wiped down before its photoshoot. (Drive)
2021 Drive Car of the Year: The full list of winners
Car of the Year: KIA Sorento
Best Upper Large SUV: Nissan Patrol
Best Medium SUV: Toyota RAV4 Hybrid
Best Small Luxury SUV: Mercedes-Benz GLS
Best Large Luxury Car: Audi A6
Best Medium Luxury SUV: Volvo XC60
Best Large Luxury SUV: Volkswagen Touareg
Best Medium to Large Car: Toyota Camry Hybrid
Best Small SUV: Skoda Kamiq
Best Sports Performance SUV: Audi RSQ8
Best Off-Road SUV: Land Rover Defender
Best People Mover: Kia Carnival
Best Large SUV: Kia Sorento
Best Electric Vehicle: Audi e-Tron
Best Light SUV: Ford Puma
Best Dual Cab Ute: Isuzu D-Max
Best Van: Toyota Hiace
Best Small Car: Toyota Corolla Hybrid Hatch
Best Sports Car Under $100k: Mercedes-AMG A45 S
Best Sports Car Over $100k: Porsche 911 Turbo S
Best Small Luxury Car: Audi A3
Best Innovation: Hyundai Nexo
Best Overall Value: MG ZS Range
Best City Car: Volkswagen Polo
Best Medium Luxury Car: BMW 3 Series
For more information and detailed analysis of each winner, visit www.drive.com.au.
Floods wreak havoc on western NSW


text:
Tuesday, January 19th, 2021 Profile|Contact|
Home | Profile | Freedom | Philosophy | Technology | Other topics | Links & Resources
Navigation...
The Task of Philosophy
Richmond Signage challenge
Freedom - Canadian Charter of Rights and Freedoms
On November 11, 2013, a fellow LinkedIn.com member named Andrew Pezza challenged "The Philosophy Network" group with this question: "What does everyone here believe the task of philosophy is in today's society? I find that question to [be] better than asking what philosophy is."
My response on November 12, 2013, was the following two paragraphs:
I regard philosophy as a means to gain a better understanding of the moral, ethical, and social values and the effects and implications these values can and do have on individuals as well as societies as a whole. Often overlooked is that skepticism is also an essential part of philosophy as it provides an important analytical ideology for "questioning everything" to gain that "better understanding."
My concern with philosophy is that it is often limited by restrictions placed upon freedom of expression as there is tremendous pressure by many to impose draconian laws that protect ideas before people and animals, or some sort of a "licensing system" that is designed to protect the feelings of others. Unfortunately such limitations are at odds with "freedom," which I regard as a form of "dysfunction" since it conflicts with the fundamental nature of the experiences that come from "living," thus I firmly believe that these "erosions of freedom" ultimately tend to do far more harm than good.
Copyright © 2001-2020 Randolf Richardson. Beautiful British Columbia, Canada.
All rights reserved. All trademarks are the property of their respective owners.

redpajama_set_name: RedPajamaCommonCrawl


text:
package io.aos.concurrent.spl0.cs08.example3;

import java.util.*;

public class CharacterEventHandler {
    private ArrayList listeners = new ArrayList();

    public void addCharacterListener(CharacterListener cl) {
        synchronized(listeners) {
            listeners.add(cl);
        }
    }

    public void removeCharacterListener(CharacterListener cl) {
        synchronized(listeners) {
            listeners.remove(cl);
        }
    }

    public void fireNewCharacter(CharacterSource source, int c) {
        CharacterEvent ce = new CharacterEvent(source, c);
        CharacterListener[] cl;
        synchronized(listeners) {
            cl = (CharacterListener[] )
                                 listeners.toArray(new CharacterListener[0]);
        }
        for (int i = 0; i < cl.length; i++)
            cl[i].newCharacter(ce);
    }
}

redpajama_set_name: RedPajamaGithub


text:
Scholarly Awards
CK Prahalad Award
Emerging Scholar Award
Journal Awards
SMJ Best Paper Prize
SEJ Best Paper Prize
GSJ Best Paper Prize
Conference Best Paper Prize
Conference PhD Paper Prize
SMS Special Conference Award
Practitioner Awards
CK Prahalad Awards
Service Award
Emerging Market Multinationals and the Theory of the Multinational Enterprise
by Jean-François Hennart
Reverse Innovation, Emerging Markets, and Global Strategy
by: Vijay Govindarajan and Ravi Ramamurti
2019 Winning Paper
Acquisitions as entrepreneurship: asymmetries, opportunities, and the internationalization of multinationals from emerging economies
Global Strategy Journal
Anoop Madhok
...is a Professor of Strategy and the Distinguished Scotiabank Professor in International Business & Entrepreneurship at the Schulich School of Business, York University, Toronto, Canada. He was earlier a Professor of Strategic Management at the University of Utah, USA and has held...
Mohammad Keyhani
...is an Associate Professor in Strategy and Entrepreneurship at the Haskayne School of Business, University of Calgary and a David Rockefeller Fellow at the Trilateral Commission. He is the maker of the Entrepreneur Tools website...
Interview with 2019 GSJ Best Paper Prize Winners
Award Overview
The Global Strategy Journal Best Paper Prize is presented annually to honor substantial work that is published in the Global Strategy Journal. Papers are considered eligible after five or more years from the date they are published. This delay allows for the impact of the paper to be assessed in terms of citations and influence of the paper on teaching, research and/or practice. Once a paper becomes eligible for this prize, it remains eligible until it is selected for the award. Authors of the winning paper receive a monetary award of USD 5,000 along with a plaque at the SMS Annual Conference.
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Biophilic design celebrates the natural environment by intentionally incorporating elements from nature into the built environment. Designers and medical professionals have found that biophilic buildings create spaces in which people are happier, healthier and more productive. Get inspiration and practical design guidelines from a celebrated international biophilic design expert who was named one of the top ten most powerful women in sustainability in 2015 as a recipient of the Women in Sustainability Leadership Award.


I used to be a lawyer. Bear with me; this is relevant. To a lawyer, words matter. We're accustomed to choosing them with care. One word, in the wrong place, can make or break a contract. You want words that are fit for purpose? Hire a (former) lawyer.
What else? I'm a practised persuader. Facts don't win cases -- how you present them does. I parse complex information. I tease out the salient facts and present them in an engaging, persuasive and audience-appropriate way. For over 20 years, I've communicated with corporates who get it and consumers who don't. I specialise in helping small and medium-sized organisations formulate their message and get their communications off the ground.
Like the sound of that? Great! Take a peek at my portfolio. And if you like what you see, get in touch. I'd love to work with you!
I'm a former corporate lawyer and hold postgraduate degrees in law and business. They even come in useful, sometimes.


text:
Сухогрузы типа С-3 — третий тип сухогрузов, разработанный в 1930-е годы Морской комиссией США (MARCOM). В период с 1939 по 1947 годы было построено 465 судов.

В годы Второй мировой войны часть судов была переоборудована в эскортные авианосцы и корабли снабжения.

См. также

 USS Long Island (CVE-1);
 Эскортные авианосцы типа «Эвенджер»;
 Эскортные авианосцы типа «Боуг».

Сухогрузы

redpajama_set_name: RedPajamaWikipedia


text:
Q: Authentication error using new Pulumi azuread module I've installed the latest Pulumi azuread module and I have this error when I try a pulumi preview:
Previewing update (int):

     Type                          Name                Plan     Info
     pulumi:pulumi:Stack           test-int
     └─ azuread:index:Application  test                         1 error

Diagnostics:
  azuread:index:Application (test):
    error: Error obtaining Authorization Token from the Azure CLI: Error waiting for the Azure CLI: exit status 1

my index.ts is very basic:
import * as pulumi from "@pulumi/pulumi";
import * as azure from "@pulumi/azure";
import * as azuread from "@pulumi/azuread";

const projectName = pulumi.getProject();
const stack = pulumi.getStack();
const config = new pulumi.Config(projectName);

const baseName = `${projectName}-${stack}`;

const testRg = new azure.core.ResourceGroup(baseName, {
    name: baseName
});

const test = new azuread.Application("test", {
    availableToOtherTenants: false,
    homepage: "https://homepage",
    identifierUris: ["https://uri"],
    oauth2AllowImplicitFlow: true,
    replyUrls: ["https://replyurl"],
    type: "webapp/api",
});

Creating resources and AD application with the old module azure.ad works fine.
I have no clue what I am missing now....
EDIT:
index.ts the old way
import * as pulumi from "@pulumi/pulumi";
import * as azure from "@pulumi/azure";

const projectName = pulumi.getProject();
const stack = pulumi.getStack();
const config = new pulumi.Config(projectName);

const baseName = `${projectName}-${stack}`;

const testRg = new azure.core.ResourceGroup(baseName, {
    name: baseName
});

const test = new azure.ad.Application("test", {
    homepage: "https://homepage",
    availableToOtherTenants: false,
    identifierUris: ["https://uri"],
    oauth2AllowImplicitFlow: true,
    replyUrls: ["https://replyurl"]
});

Result of pulumi preview:
Previewing update (int):

     Type                     Name                Plan       Info
     pulumi:pulumi:Stack      test-int
 +   └─ azure:ad:Application  test                create     1 warning

Diagnostics:
  azure:ad:Application (test):
    warning: urn:pulumi:int::test::azure:ad/application:Application::test verification warning: The Azure Active Directory resources have been split out into their own Provider.

    Information on migrating to the new AzureAD Provider can be found here: https://terraform.io/docs/providers/azurerm/guides/migrating-to-azuread.html

    As such the Azure Active Directory resources within the AzureRM Provider are now deprecated and will be removed in v2.0 of the AzureRM Provider.

Resources:
    + 1 to create
    2 unchanged

EDIT 2:
I'm running this on Windows 10:

*

*az cli = 2.0.68

*pulumi cli = 0.17.22

*@pulumi/azure = 0.19.2

*@pulumi/azuread = 0.18.2

*@pulumi/pulumi = 0.17.21

Here are my principal permissions for Azure Active Directory Graph:

And the permissions for Microsoft Graph:

A: I ran into this issue and after hours I realized Fiddler was somehow interfering with the Az CLI running

redpajama_set_name: RedPajamaStackExchange


Congratulations to the AMS Fulfillment Employees of the Month for March! We are very grateful to these outstanding members of our corporate family! Thank you Jason I., Mike R., Yolanda R., Jose R., and Dovon H.
AMS Fulfillment occupies a number of facilities in Santa Clarita, CA, and employs several hundred individuals. Even though we are large, it's not difficult for us to notice the achievements of our valued employees. In fact, we make a point of it. Each month the supervisors within our facilities nominate an employee who has provided outstanding service to the clients. The nominations and supervisor comments demonstrate that the individual being recognized has gone above and beyond, and deserves Special Thanks!
I nominate Jason for employee of the month. Between ERP integrations for new business, shipping software projects, East Coast DC system maintenance, daily CS requests, and no shortage of existing client projects, Jason is tasked with a demanding and extremely complex workload. While we may not always receive the completion notice for our requests right away, Jason does a good job prioritizing open tickets and projects across 50 + accounts making sure that he and his team focus on the most critical items first. He has a knack for working with all different types of personalities including our client's staff and developers. He also has the incredible talent of staying calm in almost all situations by providing truth, facts and examples without hearsay and opinion. One could imagine that a high-level IT position is a selfless job in some respects. You only really hear from your coworkers and clients if there is a new issue or request, so I wanted to nominate Jason to show much we really appreciate him. His IQ systems-fulfillment knowledge is awesome and he is such an incredible asset to AMS.
I nominate Mike for Employee of the Month because of his outstanding characteristics and his helpfulness. He has a positive attitude and is a hard worker. Mike does whatever he can to assist others. He always takes responsibility for his job and he cares for his co-workers and their safety. He is always on time and is willing to help others no matter how difficult it might be. He is a great worker, very respectful, and he deserves this recognition.
I nominate Yolanda because she works hard and is dedicated to AMS and to our clients. Yolanda does an amazing job in the Witherspoon building. She has excellent attendance and is one of the top pickers at Witherspoon. She pays close attention to detail and no missed picks. Yolanda's positive energy and hard work have a great impact on the success of the Witherspoon building.
Jose is a very hard-working individual and is always ready to learn new things. He has set up new challenges and gets the job done with excellence. Jose is always willing to help in any area where assistance is needed and he has great communication with his co-workers. He has 100% commitment to do the job correctly and in an efficient way the first time. He always has a positive attitude which spreads across to others. We appreciate Jose's commitment to his job.
Dovon works hard and is always willing to lend a hand to others in the department. He is great at unloading containers!! He is a team player and we appreciate having him in our department. Dovon deserves to be Employee of the Month.
These outstanding employees are the reason that AMS succeeds so well and continues to grow. Employees of the Month recognition is offered as a sincere Thank You from the AMS Fulfillment Family!


text:
Posts Tagged:abortion pill
Supreme Court could rule soon on abortion pill regulations
abortion pill,SCOTUS,Theodore Chuang
The Supreme Court could soon rule on a major abortion case, after the Trump administration appealed to maintain safety regulations of the abortion pill. The Justice Department (DOJ) filed an Aug. 26 emergency motion at the Supreme Court to halt a federal district court's decision from going into effect that would nullify federal regulations of…Read More
Senators urge FDA to label abortion pill 'imminent threat to public health'
abortion pill,fda,Ted Cruz
Nearly two dozen senators are urging the Trump administration to remove the abortion pill from the market as advocates for the drug push for its wider availability. Sen. Ted Cruz (R-Texas) led a group of 20 Republican senators in signing a letter to the commissioner of the Food and Drug Administration, Stephen Hahn, on Tuesday, asking him…Read More
Abortion pill is 'imminent' public health danger, FDA warned
abortion pill,fda,health
Pro-life leaders have asked the head of the Food and Drug Administration (FDA) to remove the abortion pill from the U.S. market, in a letter sent on Tuesday. The letter was signed by nearly two dozen pro-life leaders. They urged FDA commissioner Stephen Hahn to exercise statutory authority and classify the abortion pill mifepristone as…Read More
Calif. governor signs state college campus abortion pill mandate into law
abortion pill,California,campus,Gavin Newsom
California governor Gavin Newsom signed into law Friday a measure requiring public universities to provide free access to medical abortions for students. The law will take effect in 2023, and applies to the 34 campuses of the University of California and California State University. Sen. Connie Levya (D-Chino), the law's author, said Oct. 11 that…Read More


text:
Stairlifts Wilmslow - Cheshire stairlifts
Click here to find new and reconditioned stairlifts in Wilmslow, Cheshire
If you are looking for the Castle Comfort Stairlifts legendary website
Castle Comfort Stairlifts offers top brand stairlifts, keen prices and fast installs for all those seeking stairlifts in Wilmslow, Cheshire. And all work comes with our no-quibble guarantees and famous customer service satisfaction.
Give us a call today on 01625 886 599 If however, you are looking for fascinating facts about the area then feel free to read on
Stairlifts Wilmslow – Stairlifts Cheshire
Weatherfield and Wilmslow couldn't be more different, yet two of the long serving members of Coronation Street – Britain's favourite soap – live in Wilmslow, Cheshire. Real life and screen life are somewhat different no doubt!
Are you a resident in Wilmslow? Are you leading a double life? Apparently cheerful and getting on with things but secretly frustrated at no longer being able to climb those stairs? Castle Comfort Stair Lifts would love to help you. How could we assist? Well we are the national agents for all stairlift manufacturers so not only can we supply but we can also give you an unbiased opinion about the best one for you.
Want to know more? Please watch our founder Keith's short video above and then please give us a ring on 01625 886 599.
Yes William Roache who plays Ken Barlow and has starred in Coronation Street from its first episode in 1960 lives in Wilmslow as does his colleague Simon Gregson better known to all as Steve McDonald. Both characters have grown up on the street as it were, Gregson is close to completing his 22nd year. He was picked whilst still at school to play one of the McDonald twins.
Just like Weatherfield is a suburb of Greater Manchester so is Wilmslow; it is just 11 miles from the centre of Manchester and just 7 miles from Macclesfield the home of Castle Comfort Stair Lifts' Cheshire office.
Unlike the soap suburb, Wilmslow is renowned for its famous and rich residents mainly footballers and businessmen. Back in 2005 is was reportedly the home of over 100 millionaires including businessman Peter Jones – not the 'Dragon' but the founder of the Emerson Group. At that time he was thought to be worth in excess of £460 million, somewhat richer than either the Queen or Mohamed al-Fayed owner of Harrods.
Wilmslow is also home to a number of footballers such as Manchester United players, Nemanja Vidic and Park Ji-Sung as well as Alex Ferguson, Man U's manager. Arch rival Manchester City players Joleon Lescott and David Silva have both chosen Wilmslow as their home too as has Titus Bramble who plays for Sunderland.
Just 6 miles away in nearby Prestbury you'll also find a host of well-off residents who like to earn a bob or too kicking a ball about including Wayne Rooney, Robbie Savage, Carlos Tevez, Stan Pearson, Wes Brown, Owen Hargreaves and with different ball skills 'Freddie' Flintoff.
Robbie Savage who last played for Derby Country was labelled as the 'dirtiest player in the Premier League' and now presents 606 on BBC Radio Five Live. He has gone on to shine in Strictly Come Dancing on BBC TV. Dancing with Ola Jordan he has reached Wembley again – he has played at Wembley before striking up 39 caps for the Welsh national team.
If you wish your dancing was still as hot as Robbie's but actually making the stairs is the first hurdle, why not give Castle Comfort Stair Lifts a call. We've got an office in Cheshire where are team will be happy to advise you - 01625 886 599.
Take a look at our information, use the £50 voucher – even the canniest and richest businessmen will take advantage of money saving offers – and consider a new or reconditioned stairlift from us now.
What's the attraction of these parts? A short tour around Wilmslow will be enough to explain: expensive houses – prices of around £2million aren't uncommon, designer shops, cafes and restaurants all suggest the 'Cheshire lifestyle'! Its neighbour Alderley Edge is similar and has attracted a few big names of its own. It was the home of the Beckhams before David went to play for Real Madrid; and remains home for Rio Ferdinand, Michael Carrick, Christiano Ronaldo, Mikael Silvestre, Andy Cole and Stoke's own Peter Crouch!
Actress and ex Coronation Street star, Denise Welch and Richard Fleeshman also late of Coronation Street live here alongside Stuart Hall well-known as host of It's a Knockout. It is also home to two of the band members of New Order/Joy Division, Bernard Sumner and Peter Hook.
Alderley Edge and Prestbury encompasses village life with proximity to the urban conurbation of Manchester just 12 and 18 miles away respectively for access to transport links.
About Wilmslow
The name actually comes from old Anglo-Saxon for 'mound of a man called Wighelm' – not very inspiring! But the discovery of Lindow Man one of the most important iron-age finds in the country again gives Wilmslow that exclusivity. Lindow Man can now be seen at the British Museum.
Wilmslow is part of the 'Golden Triangle' with Alderley Edge and Prestbury for on-going house price rises and its affluence.
Things not to miss in Alderley Edge
The Edge in Alderley is a geological term for a red sandstone escarpment which rises 215 miles above see level and forms a horseshoe. Stormy Point is a popular place with visitors to view the surrounding countryside of the Cheshire Plains and the Peak District. It is a National Trust Site.
Engine Vein
Engine Vein is a natural fault in the rock which is rich in copper and other minerals and was excavated by Bronze Age miners and later the Romans.
Hare Hill Park and Gardens
A small 19th century estate covering 276 acres of beautiful countryside with rolling hills, the gardens at Hare Hill are home to a collection of exotic plants and wire sculptures.
This pretty village dates from Saxon times and its name is thought to mean 'Priest's fortified enclosure'. Probably chosen for this purpose as it stands on fairly high ground for a clear view of the River Bollin. In the 19th century it was big in the silk industry so many of the houses in Prestbury were built as factory or weavers' cottages. Wayne Rooney's pile is somewhat bigger than these!
Nearby Grade I listed Adlington Hall still owned by the Legh family has parts of this historic building open to visitors on published dates. It's worth taking a look at the 15th-16th century Great Hall and timber framed courtyard. Any special occasions coming up? You can hire the Great Hall or the hunting lodge!
If getting up and down those stairs would be event enough for you, then Castle Comfort Stair Lifts are the event organisers you need!
Give us a call to discuss what you need and find out just what we can do. Our local office number is 01625 886 599.
UK Wilmslow, Cheshire, UK
Stairlifts Macclesfield - Cheshire Stairlifts
Click here to find new and reconditioned stairlifts in Macclesfield, Cheshire
Castle Comfort Stairlifts offers top brand stairlifts, keen prices and fast installs for all those seeking stairlifts in Macclesfield, Cheshire. And all work comes with our no-quibble guarantees and famous customer service satisfaction.
Give us a call today on 01625 886599. If however, you are looking for fascinating facts about the area then feel free to read on.
Stairlifts Macclesfield – Stairlifts Cheshire
Here we are in Macclesfield in Cheshire. It's the home of Castle Comfort Stair Lift's Cheshire office where you can find out all about the services we offer, the reviews we get (at Macclesfield and other areas) and get advice from our local professional team.
Castle Stairlifts founder Keith himself goes back a long way in Macclesfield, well before stairlift days. He was head hunted and 'imported' there by a ceramic tile specialist in the early 1970s - as his Stoke on Trent pottery industry training made him hot property! Keith's professional contacts in 'Macc' have continued for nearly four decades. Apart from going there weekly to shop (its quicker to get from Newcastle under Lyme to Macclesfield than to Stoke on Trent's Hanley shopping centre - and it's FREE PARKING) - the stairlifts firm has it's office located at the building of the MD's friend Paul Williams Paul has continued to trim Keith's hair since he stopped being a scruffy hippy!
So, back to stairlifts - if you, or a loved one need some help up he stairs at home, then please give our Macclesfield office a call on 01625 886599. - you may even need a haircut too!
Meanwhile we'll take you on a short tour of Macclesfield's delights!
Hello all Maxonians! This is the affectionate term for someone from Macclesfield which has only come into existence in the last 20 years or so mainly via the media.
The town name Macclesfield is thought to derive from old English for 'Maccels' open country' from the Saxon Macca i.e. Macca's fields. Presumably not ancestors of Paul McCartney! It is often referred to as Silk town as it once had a thriving silk industry though more traditionally it was known as Treacle town! Legend suggests this because a ship spilt a barrel of treacle on one of the streets and all the poor rushed out to scoop it up. It is more likely to be that the mill owners supplied unemployed weavers with barrels of treacle!
Macclesfield is a happy town according to a survey carried out just three years ago. In fact it was the 5th happiest of 273 areas in Britain. The survey was carried out by the Universities of Sheffield and Manchester which asked residents to rate themselves in terms of personal well-being.
Maybe it's Macclesfield's pleasant location that makes them happy? You can find it in east Cheshire some 41 miles east of county town Chester close to the county borders with Greater Manchester, Derbyshire and Staffordshire. It is only 20 miles north of Castle Comfort Stair Lifts 'home town' of Stoke on Trent and 18 miles south of Manchester and the Peak District is just a stone's throw away in the east.
In fact Macclesfield and Buxton (12 miles away in neighbouring Derbyshire) are joined by The Cat and Fiddle Road which is named after the pub which sits at the top. It has great views over the Peak District, the Cheshire Plains and the conurbation of Greater Manchester, and is regularly named the most dangerous road in Britain and which has become a popular ride for motorcyclists.
Did you know that Macclesfield is the original home of Hovis bread – not the pretty southern hill (Gold Hill, Shaftesbury, Dorset) that the old advert used to show?
The small village of Disley still within the Borough of Macclesfield and just 10 miles from the town is close to nearby Lyme Park, a large estate with a Tudor mansion. Disley itself was once home to at least one cotton mill, its name in Anglo-Saxon means windy settlement presumably because of its geographical location on the edge of the Peak District. It still retains its old world charm and has a few famous connections: TV presenter David Dickinson once had an antique shop here – his first; it's the birthplace of author Christopher Isherwood; British historian AJP Taylor lived here.
Do you still have old world charm? Do you typify Maxonians in being happy? Let Castle Comfort Stair Lifts make you even happier with their offering of a wide range of stairlifts. As the national agent for all stairlift manufacturers we can be sure to find the right one for you either brand new, reconditioned or even in part-exchange for your old one.
Why not watch our video when our founder Keith explains how and why the company came about and then give us a call on 01625 886599 to discuss how we can help? In the meantime take a look at the price comparisons on our website.
Interesting buildings
The 17th Century Macclesfield Town Hall at the heart of this market town is still very much in use for council business but also as an event venue and for private hire.
Armoury Towers was once the home of the Militia in Macclesfield during the 19th Century but this beautiful Grade II listed building is now private apartments.
The Grade I listed building at Lyme Park was built in the 16th century by the LeighsPemberton, Darcy's home in the BBC's Pride and Prejudice and in complete contrast was a location used in an episode of Red Dwarf.
Famous Maxonians
Macclesfield is the home town of blues singer John Mayall; Ian Curtis of Joy division grew up here as did his band-mate Stephen Morris; Gillian Gilbert also hails from here and she later joined Stephen Morris to form New Order and is married to him too.
Stoke City player Peter Crouch was born in Macclesfield; he has become famous for his robotic celebratory dance. The dance was apparently inspired by the Arctic Monkeys' song, 'I bet you look good on the dance floor'.
Jonathan Agnew, cricketer turned commentator was born here too; as was Olympic yachtsman Ben Ainslie.
Former Radio 4 Presenter on the Today programme, Brian Redhead was born and died here; author Vera Brittain who wrote Testament of Youth about her experiences in WWI spent part of her childhood in Macclesfield.
Can you recall some memories from times gone by when you were more sprightly? We bet you can. Let Castle Comfort Stair Lifts help lift your spirits with some assistance to get up those stairs.
We can supply straight and curved stairlifts which ever suits you best. If the outlay is too much there are grants available or if you can't wait for the process of applying then you could consider a 0% finance deal.
Why not give us a call to find out more on 01625 886599 and don't forget you can use our £50 voucher towards your purchase.
UK Macclesfield, Cheshire, UK
Stairlifts Widnes - Cheshire Stairlifts
Click here to find new and reconditioned stairlifts in Widnes, Cheshire
Castle Comfort Stairlifts offers top brand stairlifts, keen prices and fast installs for all those seeking stairlifts in Widnes, Cheshire . And all work comes with our no-quibble guarantees and famous customer service satisfaction.
Give us a call today on 0151 676 2727 If however, you are looking for fascinating facts about the area then feel free to read on.
Stairlifts Widnes – Stairlifts Cheshire
Entrepreneur John Hutchinson was referred to as the father of Widnes in Cheshire. He gained this title because he built and opened the first chemical factory in 1847 which literally catapulted Widnes into existence. Before this it had just been a number of smaller settlements. From this start Widnes became the chemical capital of the UK as other factories sprung up.
If you have no spring in your step then please let us help. We are Castle Comfort Stair Lifts and we supply stairlifts to help you keep moving! Our local office in Macclesfield can advise you on the best one for you or any other of our aids to keep you sprightly.
Please give the Macclesfield office a call on 0151 676 2727.
As you'll have gathered we are in Widnes in the county of Cheshire. Widnes claims the northern bank of the Runcorn Gap opposite the town of Runcorn which we visited recently. Like Runcorn, Widnes has a dock and access to the waterways and the railway which meant that all chemicals produced in this town were easily transportable both all over the UK but also overseas.
Though John Hutchinson started the whole chemical industry in Widnes at the tender age of 22, he didn't stop at one factory; he went on to own several others and into partnership with other manufacturers too. Other chemical plants grew up fronted by other entrepreneurs John McClelland, William Gossage, Frederick Muspratt, Holbrook Gaskell a local magistrate whose sister-in-law was the author Elizabeth Gaskell and Henry Deakin who at one time worked for Hutchinson.
Hutchinson manufactured Alkali used in the glass, textile, soap and paper industries for production, but a number of other substances were also produced in Widnes including soap, borax, soda ash, salt cake and bleaching powder.
All this industry whilst earning Widnes riches didn't gain it any accolades, quite the opposite in fact. In 1888 Widnes was claimed to be 'the dirtiest, ugliest and most depressing town in England' and later as 'a poisonous hell-town'.
It did bring a lot of work to the area though and not only attracted workers from other parts of England but also from Ireland – many flocked to England looking for work during the potato famine – Wales, Poland and Lithuania.
By the 1890's the chemical production industry here was already in decline as more efficient production methods were developed in other places. However, Widnes still has a big chemical industry to this day and over the last century as production methods have improved, the town has been 'cleaned up' and Widnes is looking better!
Spike Island, affectionately referred to as Spikey locally, is evidence of this. This area in Widnes was the home to many of the factories so that it became a maze of abandoned and disused buildings used for production, railway lines, canal docks and industrial pollution all of which has now been reclaimed as woodland, wetlands and green space.
One remaining old warehouse houses the only museum in the UK dedicated to the chemical industry, Catalyst Museum or the Catalyst Science Discovery Centre to give it its full title.
The building that houses the museum was originally known as Tower Building and was built by our old friend John Hutchinson for his factory office and later became the HQ of the Gossage Soap Production Factory.
What can you see at the museum? Hands on scientific exhibits, an overview of the historical development of this industry and original documents and films. There is also information about jobs and career opportunities within the industry and a glass observatory built on to the old building where you can not only view the surrounding landscape but also see exhibits dealing with the important topic of recycling.
Connections to notable people
Did you know that Spike Island hosted an outdoor concert for The Stone Roses in 1990? Two members of this 'Manchester' band are Cheshire 'boys': Ian Brown lead singer was born in Warrington and John Squire in Altrincham.
Paul Simon is said to have penned Homeward Bound on Widnes Station. A quote from Simon says, "If you know Widnes, ... you'll understand how I was desperately trying to get back to London as quickly as possible. Homeward Bound came out of that feeling."
Maybe you can't escape Widnes or maybe you need help to appreciate it more? Castle Comfort Stair Lifts are here to do just that. We hope this short arm chair tour helps you to appreciate this industrial town.
If you would like to talk to us about stairlifts or other aids, if you'd like advice on which type of stairlift is right for you and your budget, if we can help in any way, please give us a call on 0151 676 2727– don't forget to watch our video for information too.
More did you knows:
· Mel C one of the pop group The Spice Girls went to school in Widnes
· Actor David Dawson acclaimed for playing Tony Warren in The BBC 4 production of the Road to Coronation Street was born in Widnes and went to the same school as Mel C
· Professional snooker player Andrew Higginson comes from Widnes
· Physicist and Nobel Prize winner for his work on x-rays Charles Glover Barkler also hails from here
· German chemist, Ludwig Mond came to Widnes during the industrial revolution, stayed and took on British nationality; he worked with many of the other industrialists of the time and also formed the Society of Chemical Industries which still has its head quarters in Belgrave Square, London
You may not be as celebrated of any of these famous people but you still deserve some dignity to get around. At Castle Comfort Stair Lifts we recognise this; our founder Keith who you watched in the video knows from personal experience how important it is to retain this for yourself or loved ones.
At Castle Comfort Stair Lifts we can not only help you source a suitable stairlift, be it brand new or reconditioned, we can even point you in the right direction to find grants to fund the purchase or to 0% finance to make buying your stairlift easy.
Don't hesitate to contact us to find out more about how to buy the right stairlift for your needs -0151 676 2727.
UK Widnes, Cheshire, UK
Stairlifts Ellesmere Port - Cheshire Stairlifts
Click here to find new and reconditioned stairlifts in Ellesmere Port, Cheshire
Castle Comfort Stairlifts offers top brand stairlifts, keen prices and fast installs for all those seeking stairlifts in Ellesmere Port, Cheshire . And all work comes with our no-quibble guarantees and famous customer service satisfaction.
Give us a call today on 0151 676 004 If however, you are looking for fascinating facts about the area then feel free to read on.
Stairlifts Ellesmere Port – Stairlifts Cheshire
Here we are in Ellesmere Port in Cheshire on the banks of the Manchester Ship Canal, an industrial town and port. Maybe you're looking for stairlift suppliers in the area? Look no further, Castle Comfort Stair Lifts at your service!
We have a local office in Macclesfield where our expert team will be on hand to offer you all the information you need to know to help make that final decision. Remember that we guarantee our work so you can be sure any installation you set up with us will be worth its weight in gold/salt.
Talking of weight, our cheshire stairlifts can hold weights up to 30 stone so if you're a little heavy, please don't let that put you off. Talk to us today to see what we can suggest on 0151 676 004.
So here we are in Ellesmere Port another town hugging the bank of the Mersey – or the Manchester Ship Canal in this case. With all the industry that has grown up in the area and with access to the open waters and also to the canal system, it is little wonder that so many of these Cheshire towns are home to ports.
The biggest industrial contributors to the area are Stanlow Oil Refinery – mentioned by Orchestral Manoeuvres in the Dark on one of their tracks – and ICI. Vauxhall Motors also produce their Astra cars here, now Vauxhall's only plant in the UK.
The waterways
Ellesmere Port is located where the Ellesmere Canal meets the Mersey. The canal was built as part of a project to join three rivers namely the Severn, the Mersey and the Dee. The canal does connect to the River Dee at Chester but the project was never completed so the link to the Severn was never made.
Ellesmere Canal joined the Mersey at the village of Netherpool later to become Ellesmere Port. The canals were used to transport raw materials, produce and food across the country in the 18th – 19th centuries; it was a cheap and efficient method and made excellent use of the 100+ canals that were built. Railways effectively killed-off the industrial use of the canals as the railways were faster.
Ellesmere Port is fittingly home to the National Waterways Museum where visitors enjoy an historic boat collection, the pump house and a visit to the blacksmiths or a cruise up the Manchester Ship Canal.
The visitor map is helpful marking trails suitable for push chairs and wheelchairs. There is a lift – though not one of ours – to get you to the top of the Exhibition Hall.
Whilst we're on the subject, remember that Castle Comfort Stair Lifts can help you get about especially in your own home – though we do also supply commercial wheelchair and passenger lifts.
Our local office Macclesfield will be happy to advise and as we are the national agents for all UK manufacturers, there will be something that suits you, your home and your pocket.
Please call Castle Comfort Stair Lifts for more information on 0151 676 004.
Staying with the water theme, something all ages can enjoy is the Blue Planet Aquarium where youngsters can swim with sharks or see 'amazing amphibians' including a number of frogs – red-eyed tree, golden or green dart frogs, tomato frogs and more.
Another part of the attraction is the Aquatheatre where you can see and hear about some interesting water creatures including the beautiful but aggressive French Angel Fish, the Big-eyed Squirrel Fish that sometimes swims upside down and the Atlantic Spadefish that favours ship wrecks; or enjoy the Pirate's Playground.
People of note with connections to Ellesmere Port
The Cheshire Cat first appeared in Alice's Adventures in Wonderland by Lewis Carroll. Unfortunately the Cheshire Cat with his knowing grin is completely fictional. Its origin beyond Alice is unsubstantiated; it could be a reference to happy cats in the County of Cheshire where so much milk is produced! Or from cheese production when cheese was sold in moulds resembling a cat who was grinning! When 'grinning like a Cheshire Cat' refers to humans it means that we are grinning showing our teeth and gums!
English footballer Sam Chedgzoy was born in Ellesmere Port and played for Everton. Controversially he changed the laws of English football when he scored a goal – well almost – dribbling the ball from a corner. The year was 1924. Prior to this, goals from corners were only allowed if another footballer also had contact.
Ex Deputy Prime Minister John Prescott who served under Tony Blair went to school in Ellesmere Port. Beverley Hughes aka Baroness Hughes of Stretford was born in the area and also served under Tony Blair.
Comedian Hardeep Singh Kohli, star of radio and TV lived in nearby Little Sutton. 'Charles Bronson' aka the most violent criminal in Britain lived and committed offences in the area; he began his career as a bare-knuckle boxer in the East End of London.
If you're not grinning like a Cheshire Cat or you're feeling like a bare-knuckle fight to get what you need, remember Comfort Castle Stair Lifts are here to help.
No need to rage if you're frustrated that you can't get about like you used to or if you think you can't afford a stairlift. Castle Comfort Stair Lifts can point you in the direction of funding through grants or even 0% finance so that you can take advantage of our £50 voucher immediately.
Don't forget we can also offer you a chance to part-exchange your old stairlift or take a look at our reconditioned models too that might fit your budget better. Whatever you do, give us a call so that we can discuss your needs and come up with a solution. Our local office number is 0151 676 004.
UK Ellesmere Port, Cheshire, UK
Stairlifts Runcorn - Cheshire Stairlifts
Click here to find new and reconditioned stairlifts in Runcorn, Cheshire
Castle Comfort Stairlifts offers top brand stairlifts, keen prices and fast installs for all those seeking stairlifts in Runcorn, Cheshire. And all work comes with our no-quibble guarantees and famous customer service satisfaction.
Stairlifts Runcorn – Stairlifts Cheshire
Industrial town and coastal port Runcorn in the north west of Cheshire is our destination today. The captain of the Titanic, Edward Smith bought a retirement home in Runcorn but never lived there as he went down with his ship.
If your 'retirement' home could benefit from a stair lift, then please get in touch with Castle Comfort Stair Lift's local office. Their expert advisers can explain the benefits of the various chairs we supply as national agents for all stairlift manufacturers.
Take a look at our video first and then give us a call on 0151 676 2727.
Runcorn sits on the southern bank of the Mersey opposite Widnes on the northern bank; this is where the Mersey estuary narrows to form the Runcorn Gap. It is just 16 miles to Liverpool going west and 8 miles to Warrington one of our earlier destinations going east.
Runcorn was a health resort back in the 18th and early 19th centuries but as the industrial revolution took hold and industries in the area developed, Runcorn took advantage of its location and became a port. Its links to the canal systems that were being built meant Runcorn had access to the sea and to the interior waterway system of the UK for perfect distribution of any products.
In the 19th century Runcorn Railway Bridge was built across the Runcorn Gap joining the north and south banks of the Mersey for easier transport. Last century the Silver Jubilee Bridge was built nearby so that in most photos you see both bridges.
Film location
Runcorn has often been used as a film location, so much so that it has been nicknamed Woollywood; part reference to Hollywood with the Woolly coming from the nickname for the Liverpool dialect, Woolyback and also given to folk from the north bank of the Mersey.
Merseybeat a BBC police drama was filmed in Runcorn as was the same network's situation comedy Two Pints of Lager and a Packet of Crisps about the lives of a group of twenty-somethings. It was written by eighteen year old Susan Nickson for whom Runcorn is hometown. The title comes directly from punk band Splodgenessabounds' 1980 hit single 'Two Pints of Lager and a Packet of Crisps Please'.
A BBC Three drama, Drop Dead Gorgeous was also set in Runcorn; the title sequences showed shots of the Silver Jubilee Bridge and Halton Castle.
If you're the wrong side of twenty-something and need a little help or if you're no longer able to 'walk the beat' as often as you'd like, why not let Castle Comfort Stair Lifts lend a hand? Our local office can offer all the assistance you need to source the right stairlift for you.
If you need assistance to purchase, we can give you information about funding grants or details of 0% finance deals for more instant help. Don't forget we also offer a part-exchange deal to trade in your old stairlift for a new one and some cash. You can even use our £50 voucher towards it. Give Castle Comfort Stair Lifts a call on 0151 676 2727.
Listed buildings in and around Runcorn
Just like Chester, Runcorn is steeped in history. It has 59 listed buildings!
Halton Castle dates back to the 12th century probably originally built of timber and then later of local sandstone. It was held by the Royalists in the Civil War. There is a connection to John of Gaunt and his son Henry Bolingbroke, later King Henry IV of England and certainly once he was king, the Castle became part of the Duchy of Lancaster. The Castle is in ruins now but the former Courthouse rebuilt in the 18th century survives as the Castle Hotel.
The oldest standing building in Runcorn is Seneschals House in Halton. It was originally built in the 16th century for Judge John King.
Only one wing of 15th century Hallwood Mansion also in Halton survives as a public house.
Just three miles from Runcorn in the village of Norton is Norton Priory it was a 12th century Augustinian Abbey, now you can see the excavated ruins, a museum, the surrounding gardens as well as the walled garden which was redesigned in the 1980's.
The Georgian Bridgewater House was built in the 18th century near the canal of the same name.
In nearby Danesbury you can still see Danesbury Hall built in the 18th century as a former home. This Georgian beauty has three storeys and seven bays; it is now owned by the charity Scope and used as a residential home.
Who do we know from Runcorn?
Current celebrities Nicola Roberts of Girls Aloud formed after they won Popstars the Rivals in 2002 comes from Runcorn as does comedian John Bishop and a regular visitor to the area is Kym Marsh ex Hear'Say singer – the 'manufactured' band won Popstars in 2001 - and Coronation Street star. Gary Barlow of Take That fame was born in nearby Frodsham; he is a Warrington Wolves supporter. Mezzo-soprano Alice Coote also comes from Frodsham.
Physicist John Holt was born in Runcorn. He went on to win the Nobel Prize for Physics and to play a part in the development of the atom bomb. 19th century businessman Thomas Hazlehurst also hails from here; a staunch Methodist, he was responsible for building 12 Methodist chapels and 3 schools in the area and carried on the family business Hazlehurst & Sons in chemical manufacturing.
OK we're at the end of our short tour of Runcorn and you know the drill. If you are still looking for a stairlift, Castle Comfort Stair Lifts are the people to contact. Our local office will be able to help you with all aspects of sourcing and funding if necessary.
Check out our comparisons on our website and then give us a call on 0151 676 2727.
UK Runcorn, Cheshire, UK
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making connections, looking for jobs, staying up on news, etc.) by providing cutting-edge online education to a global population of people looking to make it in the ever-evolving entertainment industry. There's a community feel even to our education. Jon Sperry – a highly respected dialect coach who has worked with Harvey Keitel, Sofia Vergara, and Russell Crowe – taught a Stage 32 class that was attended by members from over 40 different countries.
This is part of my ongoing series Startup Advice. In these many exchanges similar questions crop up. Either you're not a good leader and he shouldn't be investing at all, or he has no clue what it takes to build a startup.&#. They speak up on every topic.
Several people have been asking me to weigh in publicly on the "20 under 20″ initiative announced by Peter Thiel in which he will award up to $100,000 to 20 people under the age of 20 who agree immediately to pursue entrepreneurship (the implication of which is that they'd drop out of university to do so). The value of a college education. I am very passionate and on record about the value of education. Education is self discovery.
Other Disney startups such as Atom Ticket , a new movie ticketing app, partnered with the next Star Wars movie and will continue to work with Walt Disney Studios on major film releases. Meet the 11 startups for 2017: Ambidio. Read more about startups in the Los Angeles area at TechCo.
Launchpad LA today announces it will accept applications for its third class of Los Angeles-based tech startups. But the most important metric has been the deep and lasting relationships that have been built with startups and also between senior executives.
We caught up with Grant to learn more about The Foos and his quest to use the principles of software programming to help kids learn. When you improve your sequencing skills, your reading comprehension sklils go up.
The group--which was started by Richard Koffler and John Morris , two well known investors in Los Angeles--has been trying to help connect CEOs with interesting university and other technology projects. I think if we can start six companies, that would be thrilling.
Let me start with the news that I'm excited to share with you. Startup CEO experience (Founded P.S. XO along with my good friend Soleil Moon Frye. Her network from her educational institutions alone has friends in all of the top tech, media & banking institutions.
Silicon Beach Fest is gearing up to showcase the most promising startups and visionaries from across LA's growing startup entertainment ecosystem. Panel titles include "Meet the Investors," "Celebs and Startups," "Fashion Content," "Growing Your Online Audience," and more.
However, you do not need to start a business to begin exercising your entrepreneurial muscles. Advise A Startup. "By You may be thinking, "I am not qualified to advise a startup. Who you are – your interests, experiences, education, why you are so bloody interesting.
By spending more time educating your board on your business you get more valuable advice from them. And as Rob points out – if you email members with short updates more frequently they are more up to speed when you do need them to weigh in. You start to act cohesively as a group.
This is part of my Startup Advice series. So I was surprised at the sheer volumes of decisions that had to be made when I became a startup CEO. Somebody asks whether you plan to set up 401k's and do contribution matching. But I bring up this story for a reason.
Adeo Co-Founded the entrepreneur-friendly website The Funded and he is the Founder and CEO of The Founder Institute , whose goal is to create and foster local startup ecosystems across the globe. At the time, there were about 25,000 technology businesses started every year.
The program is based on a highly developed process created by entrepreneurial thought-leader and Ivy League educator Steve Blank , author of the book The Four Steps to the Epiphany. The post StartupWeekend Next Teaches Teams How to Level Up appeared first on TechZulu.
Jason Calacanis started this initiative in response to the pay-to-play network of angel events that he despised. I suppose I should keep it to myself but I guess Jason will be helping to hype up all the companies anyways.
We will be selecting 10 startup companies to participate. Encourage the most successful LA tech entrepreneurs who had previously started companies to get involved as mentors, instructors or just informal advisors. Today we announced Launchpad LA V2.
There has recently been a common theme among the entrepreneurs I have interviewed and the conferences I have attended: despite the relatively weak state of the world economy, now is a great time to create a high-tech startup. If there was ever a time to start a company, this is it.".
We caught up with Fuel50 founder and CEO Anne Fulton to learn more about the startup. Anne Fulton: Fuel50 is a career pathing startup, part of the HR technology landscape. You can find a mentor, a coach, a project, or experience, to help you prepare for the role you are looking for. How did you start the company? We were originally operating as a coaching company, and we built out this assessment technology for our own clients.
Diamond Bar-based LifeRay (www.liferay.com) is a company that not too many people have heard of, but which is used to run the websites for such well known organizations like Toyota, T-Mobile, Coach, Fujitsu, Allianz, and Sesame Street. How did the company start? Bryan Cheung: Our two software architects had worked on this for four years, before starting the company. What's the biggest lesson you've learned so far taking this from startup to $100M?
In 2016, the renowned international university programming tournament — attended by student competitors, coaches, and parents — took place in Phuket, Thailand. But longtime ICPC student coach Antonette Logar, Ph.D., It took up every square meter of our 20,000 square meter center.
Jonathan Lehmann: I was awarded the Larry Wolfen Entrepreneurial Spirit Award at UCLA, after getting amazing coaching from Matt Ridenour in our business plan development class. We have a really good team that brought this site up.
Becka Klauber Richter is co-founder of the startup, and spoke to us about the company, which she co-founded with Kasey Edwards. What's your background, how did you start the company? I started as a teenager, and I did babysitting, life guarding, and swim coaching.
Natalia not only wants to increase the number of women in investment, but bring more people in total to help startups and other businesses get the capital they need. Natalia Oberti Noguera: Pipeline Fellowship is a program to educate and bring more women into the investment side of business.


text:
Główczyce may refer to:

Główczyce, Opole Voivodeship, Poland
Główczyce, Pomeranian Voivodeship, Poland


The Animated Screensaver Maker is an application that lets you create animated screensavers. You can use the templates provided by the program or your own photographs to make your computer cool and fun even during periods when he is in rest.Se you do not miss an opportunity to customize your machine, this software is a powerful ally to make the visual of your desktop only. Start gathering your images and prepare to spend hours manipulating screensavers.


It is very difficult to live without involving ourselves in various cleaning and this is because nobody wishes to stay dirty or even live in a dirty looking house or an untidy house for that matter, and this is one of the reasons that we involve ourselves in different types of cleaning each and every day of our lives, however, there are different types of cleaning for that matter and one of them can be the normal body cleaning that we got through when we are showering, the other cleaning that we can talk about is home cleaning, and this involves making our homes sparkling clean so that they can appear beautiful and presentable to our eyes and also to the eyes of our visitors.
We cannot all be well equipped in every field like the field of cleaning but there are people who are professionals who have specialized in cleaning projects and have come to develop so many ways of cleaning different sections of buildings and also cleaning for a healthy home and it is very advisable for people to call on these experts so that those who have trouble with cleaning their homes so that they can be healthy can get some help.
From a very long time ago cleaning was appreciated, and anything that is clean and tidy always catches the attention of many because nobody wants to be associated with anything that is dirty or untidy for that matter, so this is a challenge for each and every one of us who has been lagging behind in either cleaning their homes or themselves or anything else that needs cleaning because we all have to move forward in cleanliness, however, if we do not have cleaning ideas, we can always seek help.


A beautiful, balmy Summer's evening the other Friday, myself and the husband decided to relax outside in our tiny urban garden and enjoy a glass of rose wine or two and cook some dinner on the BBQ.
It was lovely, sitting there as the sun went down, listening to the birds tweet in the trees, drinking our wine, watching our steaks sizzle on the BBQ, letting a hard week be washed away by a feeling of contentment.
"BEEP BEEP BEEP BEEP BEEP BEEP BEEP!!!!!!!!!!!!!!!" emanated from the baby monitor. The chilling sound of Marigold's Snuza alarm which goes off when she is not breathing.
Wine glasses cast aside, steaks forgotten, we both raced up the stairs with our hearts in our mouths and mobiles in hand, ready to call emergency services if we needed to.
Of course, Marigold was absolutely fine. It was a false alarm. Although her peaceful slumber may have been slightly shattered by us frantically shouting "Marigold? Marigold?" on loop in her sleeping face and shaking her awake to check she was still breathing.
Back down for our lovely, relaxing outside BBQ we went, with me feeling like I was going to throw up, still shaking with the physiological response to hearing her alarm go off and imagining the worst about what sight might greet us upon running into her room.
But I have a secret. I don't think I am ready to give up the alarm. I am horribly addicted to the alarm. We have a co-dependent, toxic relationship where I know having it on Marigold provides me with the peace of mind that she is still breathing, but then I spend half my time on tenterhooks waiting for it to go off. And if it does go off it easily ruins a nice relaxing BBQ evening or an entire night's sleep.
The alarm was our reaction to Marigold's major apnea episode. When we got back from our week in hospital, she wore it 24 hours a day. We were hugely dependent on it. Even though we were assured the apnea episode had probably been an extreme response and was unlikely to happen again now she was on medication, it provided us with a much needed security blanket. Gradually, only after about six months, we weaned ourselves off having the alarm on her in the daytime. But the alarm on her nappy is still very much present at night and despite the recurrence of many false alarms recently, every one of which I think shaves a year or so off my life, I can't give it up. Not just yet.
Because having a child with a medical condition, in Marigold's case, a unique genetic condition (mosaicism trisomy 3q11), the worrying about their health never, ever goes away. It is lifelong, as is their condition. With Marigold, (although arguably you may say this of a typical child as well of course) you never know what might be round the corner.
So for the moment, the alarm stays. And hopefully one day soon, when we are all feeling stronger, we can wean ourselves off .
This entry was posted in Uncategorized and tagged 3q duplication, mosaicism, rare chromosome disorder, reflux apnea. Bookmark the permalink.
Many friends are dependent on those camera monitors for their kids and we joke about how you can get addicted to watching them nap. But this puts it in perspective Helen. I don't blame you for still wanting to have the 'security blanket',despite it being something you wait on tender hooks to hear.


The Moon at High Tide - Handsome scene from the legend of the Takasago Pine, a popular Noh play about a happily married elderly couple who are actually the spirits of two pine trees, one at Takasago and one at Sumiyoshi. Symbolic of long life and a happy union, the couple stands on the shore beneath a pine tree, raking and sweeping up pine needles. Stooped with age, Jo, the man, cranes his neck to look up at the evening sky, shielding his eyes with his hand. His wife Uba stands patiently at his side, her long white hair tied back with a narrow blue sash. White-capped waves roll onto the shore beyond. A charming depiction of this classic tale, beautifully detailed with embossing in Jo's white pants and soft shading in the water and sky.
Condition - This print with excellent color and detail as shown. Backed with paper. Light toning at edges. Please see photos for details.


text:
Cyclopamine
Hedgehog (Hh) signaling Inhibitor
Evaluation Sample
Cyclopamine is a naturally occurring Hedgehog (Hh)?specific small?molecule signaling steroidal alkaloid inhibitor, causes a profound inhibition of tumor growth, has significant anti?invasive, anti?proliferative and anti?estrogenic potency in human breast cancer cells [2] [1]. The EC50 of cyclopamine is 10.57 μM, it was identified by an FXR-bla (farnesoid X receptor- b-lactamase) assay [3].
Hh signaling pathway plays a critical role in embryonic development and tumorigenesis [4]. Hh signaling pathway shows saliency in regulating cellular proliferation and differentiation in a wide array of human tissues. It is related to aberrant cell survival in numerous human malignancies, ranging from BCCs and medulloblastomas to small cell lung, gastrointestinal, breast and prostate tumors [1].
Treated with cyclopamine (10 or 20 μM) only and incubated for time periods ranging from 0 to10 days, MCF-7 cells and MDA?MB?231 cells displayed a significant reduction in proliferation rate compared with the control cells on days 3 and 6 (P
Embryoes exposed to cyclopamine resulted in visible external defects, including cyclopia, proboscis formation, microphthalmia, thoracic lordosis, amelia and decreased body size. Examination of gastrointestinal organs revealed severe deficits, including less length of the gut tube and mesenchymal cell numbers in foregut-derived organs. Ectopic structures in duodenum, stomach, and dorsal pancreas were also found [5].
[1]. Marc J. Meth and Jeffrey M. Weinberg. Cyclopamine: Inhibiting Hedgehog in the Treatment of Psoriasis. Continuing Medical Education, 2006, 78: 185-188.
[2]. Jun Che, Fu-Zheng Zhang, Chao-Qian Zhao, et al. Cyclopamine is a novel Hedgehog signaling inhibitor with significant anti?proliferative, anti?invasive and anti?estrogenic potency in human breast cancer cells. Oncology Letters, 2013, 5: 1417-1421.
[3]. Chia-Wen Hsu, Jinghua Zhao, Ruili Huang, et al. Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs that Modulate Farnesoid X Receptor. Scientific Reports, 2014, 4: 6437.
[4]. Robert J. Lipinski, Paul R. Hutson, Paul W. Hannam, et al. Dose- and Route-Dependent Teratogenicity, Toxicity, and Pharmacokinetic Profiles of the Hedgehog Signaling Antagonist Cyclopamine in the Mouse. Toxicological Sciences, 2008, 104(1):189-197.
[5]. Seung K. Kim and Douglas A. Melton. Pancreas development is promoted by cyclopamine, a Hedgehog signaling inhibitor. Proc. Natl. Acad. Sci. USA, 1998, 95: 13036-13041.
1. Fan SM, Chang YT, et al. "External light activates hair follicle stem cells through eyes via an ipRGC-SCN-sympathetic neural pathway." Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6880-E6889. PMID:29959210
Physical Appearance A solid
Cas No. 4449-51-8
Formula C27H41NO2
Synonyms 11-Deoxojervine
Solubility ≥6.9mg/mL in DMSO
Chemical Name (3S,3'R,3'aS,6'S,6aS,6bS,7'aR,9R,11aS,11bR)-3',6',10,11b-tetramethylspiro[2,3,4,6,6a,6b,7,8,11,11a-decahydro-1H-benzo[a]fluorene-9,2'-3a,4,5,6,7,7a-hexahydro-3H-furo[3,2-b]pyridine]-3-ol
Canonical SMILES CC1CC2C(C(C3(O2)CCC4C5CC=C6CC(CCC6(C5CC4=C3C)C)O)C)NC1
Cell experiment: [1]
AA/C1, RG/C2, CaCo2, HT29 and SW480 cells
The solubility of this compound in DMSO is
20 μM, 48 hours for cell yield inhibition 10 μM, 48 hours for apoptosis induction (measured by PARP expression)
Treatment of cyclopamine significantly reduced cell yield in all the tested human colorectal tumour cell lines with a dose-dependent manner. Cyclopamine also remarkably induced apoptosis in each of the cell lines. The CaCo2 cell line showed particular sensitivity to cyclopamine-induced apoptosis.
Animal experiment: [2]
C57BL/6J mice
Intraperitoneal injection, 160 mg/kg/day for 31 hours.
Cyclopamine showed teratogenic potential in the tested animals. Affected embryos were slightly smaller than normal littermates and exhibited mild blunting of the snout as well as cleft lip and palate. Embryos exhibited unilateral and bilateral complete cleft lip with clefts extending into the primary and secondary palate. Facial clefts were often accompanied by open eyelid defects and in one embryo by forelimb syndactyly.
[1] Qualtrough D, Buda A, Gaffield W, et al. Hedgehog signalling in colorectal tumour cells: induction of apoptosis with cyclopamine treatment. International journal of cancer, 2004, 110(6): 831-837.
[2] Lipinski R J, Hutson P R, Hannam P W, et al. Dose-and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse. Toxicological sciences, 2008, 104(1): 189-197.
Description Purmorphamine is a blocker of BODIPY-cyclopamine binding to Smo with IC50 of ~ 1.5 μM and also is an inducer of osteoblast differentiation with EC50 of 1 μM.
Targets Smoothened (Smo)
IC50 46 nM
View current batch: 3 2 1
A8656 Jervine
A3021 GDC-0449 (Vismodegib)
A8658 AY 9944 dihydrochloride
A8651 LY2940680
A3258 BMS-833923
A8659 SANT-1