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LCHF on the Front Cover of US Magazine
January 6 2014 by Dr. Andreas Eenfeldt, MD in Weight loss
Who's that handsome doctor? Well, it's Dr. Eric Westman, president of the American Society of Bariatric Physicians (weight loss doctors).
According to the magazine he is "the world's number-one expert on low-carb diets" – and they may be right. I spent a few days with him at his Duke University clinic back in 2010. I've also interviewed him on video a couple of times, here's the latest interview.
The "last-chance diet" is a strict Atkins diet, virtually identical to LCHF.
Obviously the text on the front cover contains a few too-big promises. In the article Dr. Westman says he often sees 20 pounds of weight loss in two weeks and 100 pounds in a year, not that it happens to everybody. And when it comes to heart disease he only says that risk factors typically improve (that's all we know for sure).
Woman's World apparently has a circulation of almost 7 million copies. Not a bad way to spread the message.
More details on Jimmy Moore's blog
LCHF for beginners
Top comment
Reply to comment #13 by Mark
Dr. Andreas Eenfeldt, MD Team Diet Doctor
January 7 2014 10
I've never come across the results of studies such as this:
mentioned by DickK earlier.
On the surface it sounds disconcerting. Afterall, biomarkers are very often dismissed as not being relevant, eg increase in LDL in some on a LCHF diet with the argument being that there's an increase in the better sub type. However, a physical change such as that mentioned in the study of the vessels in the neck can't really be dismissed.
Thoughts anyone?
It's not a randomized controlled trial, it's observational data, meaning the groups are potentially different in X number of ways.
In a real RCT on adults the effect was the opposite:
http://circ.ahajournals.org/content/121/10/1200.full
January 8 2014 2
"The new trials with PCSK9 inhibitors are soon on the markets and allow doctors to reduce LDL in the 20s on high risk people."
Good to see Big Pharma has a new panacea in the works to flog now that the patents on statins have started to expire. What could possibly go wrong?
I eagerly await something convincing that it is the lowering of LDL that makes a difference and not other factors. At the risk of being insulted by Dickk as a "denialist" or "creationist" or whatever, I am simply not convinced at this point. Other explanations seem much more credible the more I look into the matter of the mechanisms of artery health, damage and response. Why, for example, would consumption of oxidized vegetable oils make a difference if the gradient of LDL concentration were the only factor. Perhaps a new universal drug solution is a fantastic wet dream for the Pharma Dickks seeking the next patentable cash cow they can sell as a magic bullet paid for by health insurance, but the rest of us want a long healthspan without drugs.
Z.M.
Sill waiting for Dr. Ridker to properly explain the points raised by the critics. So far he has provided no substance. Dr. de Lorgeril created a nice slide for everyone to see (could not post the link because it is being marked as spam, so search his website).
Why are you even trying you defend a trial which provided no cardiovascular mortality benefit and a possible chance mortality finding driven by fewer cancer deaths? Dr. Ridker himself acknowledged that "There was a small reduction in fatal cancers, but the steering committee believes that was likely the play of chance". Even the FDA officers found it unclear stating "Further inspection of the data shows that the Kaplan-Meier curves converge toward the end of the trial. At approximately 1600 days (4.4 years), the Kaplan-Meier estimate of the absolute difference in risk of death is 0.7% in favor of rouvastain with a 95% confidence interval (-0.4%, 1.8%). Thus, it is not clear whether or not rosuvastatin confers a total mortality advantage compared to placebo even though the logrank test appears to detect the separation of the survival curves up to over 4 years."
The Jupiter data set is simply unreliable no matter how you spin it.
FrankG
I guess what loses the most credibility for Dik Dik, is his seeming need to constantly defend his apparently insurmountable position!
He claims to have the "preponderance of evidence", to have the backing of the best minds in science and medicine, the support of "every single health organization dealing with public health on the face of this planet" and yet he evidently feels threatened by a family Doctor and a few comments on a blog?!?
Seriously?!?
One can only assume that his position is not quite so rock solid, nor unassailable, as he would try to have us believe.
Oh dear... poor little Dick :-P
BTW loss of function mutations in PCSK9 promote increased LDLR activity, allowing more LDL particles to be cleared from plasma, which reduces particle residence time. This is important because if LDL receptor expression is increased, this leads to an increase in the turnover of LDL and a decreased chance of LDL modification. Same can be said of other genetic disorders. Therefore even IF these studies could be extrapolated to the normal population it still does not prove that lowering cholesterol will reduce risk. In fact, research throughout the decades have shown that lowering cholesterol is a waste of time (http://diettrialclaims.blogspot.com/2013/06/animal-studies.html) so there is no reason to suspect that PCSK9 inhibitors will work.
charles grashow
http://circ.ahajournals.org/content/118/6/672.full
Evidence Mandating Earlier and More Aggressive Treatment of Hypercholesterolemia
One important line of evidence comes from a consideration of the Japanese experience. In 1952, mortality from CHD among Japanese men 55 to 64 years of age was <10% of what it was in the United States.15,16 Their total cholesterol levels at the time averaged ≈160 mg/dL (estimated LDL, ≈80 mg/dL). It is noteworthy that the Japanese enjoyed this relative immunity to CHD despite the fact that the prevalence of one of the major risk factors—cigarette smoking—was much higher in Japan than in Western countries,17 and another—-hypertension—was just as high.18 Even the diabetic population in Japan fares better than the diabetic population in Western countries. In 1985, almost 30% of British male diabetics but only ≈15% of the Japanese male diabetics had CHD.19 The implication is that if blood cholesterol levels are sufficiently low, the other dominant risk factors, including cigarette smoking, hypertension, and diabetes mellitus, constitute much less of a threat.
Are these large differences in incidence between Japan and Western countries based primarily on genetic factors? No. Two cleverly designed epidemiological studies showed that the Japanese who had migrated and taken up permanent residence in Hawaii had higher blood cholesterol levels and a higher incidence of CHD than those who remained on the home island. For those who migrated even further, on to California, the differences were even more striking.20,21 This and other migration studies22 showed that the differences in CHD risk among different populations are certainly not entirely genetic. Which environmental factors are at play? A number of factors could be involved, but there is reason to believe that the major factors are changes in diet and exercise patterns that predispose to elevated blood cholesterol and obesity. Keys23 reported as early as 1957 that the fat content of the diet, as a percentage of total calories, rose from 10% to 15% in Japanese on the home island to ≈30% in Japanese migrants to Hawaii and to almost 40% in migrants to Los Angeles.
A crucially important point needs to be noted here: For whatever reasons, the Japanese have their lower cholesterol levels for their entire lifetimes. Lowering the cholesterol level of a 50-year-old American for just 5 years, even if his cholesterol is successfully brought down to a Japanese-like level, is unlikely to convert his risk to a Japanese-like risk. At 50 years of age, he most likely enters the study with well-established, extensive arterial disease.24,25 It would be unreasonable to expect that all that damage could be reversed in just 5 years. The canonical 5-year trials have given us a minimum estimate of the impact of preventive management. Only after longer trials with younger subjects will we have some estimate of the maximum potential. We will return later to this key issue, the need for earlier treatment.
Is lowering LDL levels intrinsically dangerous? That possibility has been suggested in the past, but no hard evidence exists for such a concern, and a number of considerations make such an effect quite improbable.
First, levels of intracellular cholesterol are jealously guarded by the wonderfully efficient LDL receptor homeostatic mechanism elucidated by Brown and Goldstein. Consequently, lowering plasma cholesterol levels does not decrease intracellular cholesterol levels. The LDL receptor has a very high affinity for its ligand, so much so that even at plasma LDL cholesterol concentrations of 10 mg/dL, the LDL receptors in peripheral tissues would still be 50% saturated and uptake would continue unabated.
Second, we know that most mammalian species have LDL levels well below those reached in humans during even the most aggressive treatment of hypercholesterolemia (mean value, 42 mg/dL).38 Obviously, these animals' cells do just fine. In addition, cord-blood LDL levels in humans are <20% of adult levels,39 showing that growth and development of the fetus are just fine at LDL cholesterol levels <40 mg/dL.
Third, in some kindreds with hypobetalipoproteinemia, LDL cholesterol levels can be <15 mg/dL throughout life, yet the affected members show perfectly normal growth and development and actually have increased longevity.40,41
We know now from the large-scale statin trials that lowering LDL values to well below 100 mg/dL not only is safe but actually decreases overall mortality significantly.4,11,29,42–46 Thus, there should be no hesitation at all about lowering LDL levels through attention to lifestyle changes (ie, diet and exercise), in which the intervention itself carries no risks. Here, the only rule necessary is "the lower, the better."
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1985/brown-...
When LDL-cholesterol levels are below 100 mg/dl (equivalent to a total plasma cholesterol level of 170 mg/dl), heart attacks are rare. When LDL-cholesterol levels are above 200 mg/dl (equivalent to a total plasma cholesterol level of -280 mg/dl),heart attacks are frequent. Controversy arises over the middle ground, i.e.,individuals with plasma LDL-cholesterol levels between 100 and 200 mg/dl (total plasma cholesterol of 170 to 280mg/dl). This is the, range in which the vast bulk of heart attacks occur. Somewhere within this range there is a threshold value of cholesterol at which heart attacks begin to become more frequent. In this middle ground how much of the heart attack burden is attributable to plasma cholesterol? There is no definitive answer. In addition to cholesterol, heart attacks in this group are aggravated by smoking, hypertension, stress, diabetes mellitus, and poorly understood genetic factors. However, it seems reasonable to propose that plasma cholesterol does have something to do with heart attacks in these subjects, and that the incidence of heart attacks would be reduced if plasma cholesterol could be lowered
The LDL receptor studies lend experimental support to the epidemiologists' suggestion that the levels of plasma cholesterol usually seen' in Western industrialized societies are inappropriately high (9). This support derives from knowledge of the affinity of the LDL receptor for LDL. The receptor binds LDL optimally when the lipoprotein is present at a cholesterol concentration of 2.5 mg/dl (28). In view of the 10 to 1 gradient between concentrations of LDL in plasma and interstitial fluid, a level of LDL-cholesterol in plasma of 25 mg/dl would be sufficient to nourish body cells with cholesterol (118). This is roughly one-fifth of the level usually seen in Western societies (Fig. 16 and ref.119). Several lines of evidence suggest that plasma levels of LDL-cholesterol in the range of 25-60 mg/dl (total plasma cholesterol of 110 to 150 mg/dl) might indeed be physiologic for human beings. First, in other mammalian species that do not develop atherosclerosis, the plasma LDL-cholesterol level is generally less than 80 mg/dl (Fig. 16 and ref. 120). In these animals the affinity of the LDL receptor for their own LDL is roughly the same as the affinity of the human LDL receptor for human LDL, implying that these species are designed by evolution to have similar plasma LDL levels (9,119). Second, the LDL level in newborn humans is approximately 30 mg/dl (121), well within the range that seems to be appropriate for receptor binding (Fig. 16). Third, when humans are raised on a low fat diet, the plasma LDL-cholesterol tends to stay in the range of 50 to 80 mg/dl. It only reaches levels above 100 mg/dl in individuals who consume a diet rich in saturated animal fats and cholesterol that is customarily ingested in Western societies (116)
http://truthcentral.wordpress.com/2013/06/26/119/
Rebuttal to Main Cholesterol Skeptic
Of the various atherosclerotic risk factors, which one is an absolute prerequisite for development of atherosclerosis?
The answer is hypercholesterolemia. What level of total cholesterol and specifically LDL cholesterol is required for atherosclerotic plaques to develop?
Symptomatic and fatal atherosclerosis is extremely uncommon in societies where serum total cholesterol levels are <150 mg/dL and serum LDL cholesterol levels are <100 mg/dL (8). If the LDL cholesterol level is <100— and possibly it needs to be 150 mg/dL and the LDL cholesterol is >100 mg/dL, the other risk factors clearly accelerate atherosclerosis.
Reply: #56
Reply to comment #55 by charles grashow
Seriously Charles.. trying to drown everyone out with an avalanche of words? You really expect others to wade through all that? Haven't you been told before about how pointless it is to simply copy and paste vast swathes from other sites... especially when, as in this case, you have made no attempt to differentiate between what is a direct quote, what is opinion, what is your own words etc.. etc.. etc... an absolutely pointless waste of time!
Charles, have you even read my review on cholesterol? - http://diettrialclaims.blogspot.com/2013/06/animal-studies.html
You have a tendency of not communicating with others, so it would be nice if you can answer my question directly.
Reply to comment #56 by FrankG
I'll try to dumb down my answers so you can more readily understand them.
Reply to comment #57 by Z.M.
Yes I have - you just post studies that support your POV. BTW what are your academic qualifications?
Given that Dick Dick likes to claim that only a "denialist" would suggest that "every single health organization dealing with public health on the face of this planet has been wrong about diet-heart and lipid theory"...
...along with an emphasis (shared by others apparently) that "LDL" is the major culprit -- even allowing for this gross oversimplification of a complex and nuanced topic...
Here is the link to a table showing the World Health Organisation's Clinical Criteria for [the diagnosis of] Metabolic Syndrome...
http://circ.ahajournals.org/content/109/3/433/T2.expansion.html
Please read it and relay back to the class what upper level they set for "LDL" in these criteria.
I'll save you the bother... they include Plasma triglycerides and HDL cholesterol but LDL does not even get a mention!
Weird eh? Especially given the "preponderance of evidence". Or perhaps we are to take it that those with Metabolic Syndrome are not seen as high risk for CVD?
Here again we can wonder about the agenda when we only currently have drugs which effectively lower "LDL" levels... no drugs for trigs or HDL-C (although I know a dietary intervention which helps.. but where's the money in that? LOL)
Have a look at the NCEP Adult Treatment Panel III Update 2004: Financial Disclosure statement for the 9 member (self-selected) working group... and do bear in mind that these guidelines are adopted and used by many countries, not just the US of A
http://www.nhlbi.nih.gov/guidelines/cholesterol/atp3upd04_disclose.htm
72 (SEVENTY TWO) Financial Conflicts of interest across 8 of the 9 panel... 72!!!
As Dr Kendrick succinctly puts it... " the mere fact that there were seventy two financial conflicts of interest does not mean that the guidelines themselves were biased. But you know what, I don't believe it. Imagine if eight Supreme Court judges, ruling on any issue, had seventy two direct financial conflicts of interest to do with that issue…..Well, the outcry would never end"
Oh and he has a few telling words about the good Dr Ridker in the same article :-P
http://drmalcolmkendrick.org/2013/08/02/who-shall-guard-the-guardians/
Bottom line for me is that there IS controversy, it is NOT a done deal and there are HIGHLY questionable agendas relating to billion$ of dollar$ of profits... this makes me highly skeptical of ANYTHING which is presented supporting the lipid hypothesis and widespread use of statins.
All of which is to say that you would really have your work cut out to try and convince me that my current choice of diet is somehow killing me, despite all my personal evidence to the contrary.
That whole spiel was an "answer"??? What the heck was the question?!?
And if you want to start insulting my intelligence, then do expect me, going forward, to treat you with all the respect that you deserve :-P
Charles: "Yes I have - you just post studies that support your POV. BTW what are your academic qualifications?"
Then you haven't read it because I include studies that allegedly support the lipid hypothesis contrary to your claim. In other words my review includes almost all of the relevant evidence available. In fact, I take into consideration a bunch of studies in the links that you provide which is why I presented the question to you.
Charles: "BTW what are your academic qualifications?"
You asking me this question is problematic because it confirms that you are unable to review the evidence on your own, which explains why you hold the position that you do. You know, following the principles of science and logic goes a long way to filtering the BS propagated against cholesterol.
Gentlemen, is this supposed to be a productive discussion or an argument?
It is not productive to cherry pick studies, especially when there is so much evidence of manipulation of studies to suit pharmaceuticals and withholding of negative studies and blocking funding for the types of studies that might prove negative.
Further, when a renowned lipidologist such as Dr. Tom "Just take the damn statins!" Dayspring (i.e., not hostile to statins) concludes the evidence does not show elevated cardiovascular risk when the number of LDL particles is in normal range despite much higher level of LDL-C, it is difficult to ascribe much credibility to cherry-picked studies.
And arguments from cholesterol levels in other animals are utterly unpersuasive. Humans have a much bigger brain in proportion, which is to a large degree cholesterol. So anything that relates to brain will likely be different in humans because the proportionate quantum human brain needs are so different. Indeed, low cholesterol correlates to earlier onset of senility in Framington analysis: Elias, et al, "Serum Cholesterol and Cognitive Performance in the Framington Heart Study, " Psychosomatic Medicine 67, No. 1 (2005): 24-30. Dr. Perlmutter in Grain Brain cites other studies along the same lines, so something must be going on metabolically.
Where does this all leave me in terms of which side of the debate seems more credible? Going home to have some duck liver gently cooked rare in butter from grass-fed cow milk.
I have found in my personal experience that eating in this manner has raised my HDL and LDL, without putting LDL-P or apoB/apoA out of normal, has left my arteries perfectly clear, blood pressure decent (95/65), triglycerides very low, CRP below measured range and my skin and other tissues in noticeably better condition, especially during times I up my consumption of coconut oil. So absent any evidence of personal health detriment, I simply don't find the cherry-picked hysterics of Dickk convincing. Charles, at least, is human in his demeanor. But I still don't think it addresses the reasons so many people are skeptical of the gradient LDL hypothesis.
FrankG: "Oh and he has a few telling words about the good Dr Ridker in the same article"
Exactly. If anyone has the motivation to propagate nonsense about statins and CRP Dr. Ridker would be the man!
DickK
@ZM;
if statins would work mainly through some other unknown mechanism, it would be hard to explain why people with inherited mutation that lower cholesterol throughout the life via the statin targeted HMG-CoA gene have 55% reduced risk for CHD for every mmol/l (39mg/dl) lower cholesterol. The same magnitude of decreased risk for CHD is seen in people with genetic mutation that lower life-time cholesterol through a very different pathway, through the PCSKY9, in fact the result are identical with all the 9 genetic polymorphism studied so far. Tough times for being a cholesterol denialist.
Nearly all free-ranging mammalians have very low levels of cholesterol, LDL way under 70s.
Ridker explained himself in the article published in Medscape that I linked to as well as in separate the article published in American Journal of Cardiology.
Did Dr Ridker perhaps go on to explain (in the Medscape article) why it took JAMA to expose his...
"Unreported Financial Disclosures in: 'Association of LDL Cholesterol, Non–HDL Cholesterol, and Apolipoprotein B Levels With Risk of Cardiovascular Events Among Patients Treated With Statins: A Meta-analysis.'"
The fact that he had board membership with Merck Sharp and Dohme…… a company that has made billions from selling statins.
This just slipped his mind perhaps? Maybe short-term memory loss and confusion as a result of taking statins..? Although it sure would be interesting to see exactly how many of these statinators are actually risking taking their own drugs. Eh Dick? :-P
http://jama.jamanetwork.com/article.aspx?articleid=1148176
Doc. It's comical you tried to counter a weight maintenance study in children with an extremely low calorie weight loss study with adults which are using drugs.
Apples and oranges?
"if statins would work mainly through some other unknown mechanism, it would be hard to explain why people with inherited mutation that lower cholesterol throughout the life via the statin targeted HMG-CoA gene have 55% reduced risk for CHD for every mmol/l (39mg/dl) lower cholesterol. The same magnitude of decreased risk for CHD is seen in people with genetic mutation that lower life-time cholesterol through a very different pathway, through the PCSKY9, in fact the result are identical with all the 9 genetic polymorphism studied so far. Tough times for being a cholesterol denialist."
I suspect this statement will attempted to be refuted by distractions like irrational hatred of "Big Pharma" and other paranoid rhetoric.
"In scientific contexts, the denialist can deny a cause, an effect, the association between the two, the direction of the cause-and-effect relationship or the identification of the cause-and-effect relationship . Often denialists practice minimization and use misplaced skepticism to give an unwarranted veneer of scientific thinking"
Reply to comment #67 by Liam
"...Often denialists practice minimization and use misplaced skepticism to give an unwarranted veneer of scientific thinking"
...while others try to skulk around behind the anonymity of yet another pseudonym in the mistaken belief that their style of writing will not betray them as still being a little... Dick! LOL :-P
Frankg...While others impart even more Pseudoskepticism to distract and confuse.
LDL and LDL-p are usually discordant in people with metabolic syndrome. Which is why high LDL isn't listed as a major risk factor.
It's funny you're linking to the website of confusionist Dr Malcomn kendrick. Do you know he says that diet has nothing to do with CVD?
Would you agree with that statement? Or would you pass him off as some kind of crank?
It seems we are surrounded by "confusionists" and "denaliasts" on all sides... oh dear!
Good job that we can rely on the solid foundation of such upstanding and trustworthy people as yourself... eh Dick K K K? :-P
Dick: "if statins would work mainly through some other unknown mechanism, it would be hard to explain why people with inherited mutation that lower cholesterol throughout the life via the statin targeted HMG-CoA gene have 55% reduced risk for CHD for every mmol/l (39mg/dl) lower cholesterol."
Assuming that statins actually work (I'm not convinced), the mechanism by which they are said to work is through increases in the LDLr. This is the same mechanism of loss of function mutations in PCSK9 and the many genetic disorders that you refer to. So even by the mainstream view, the data and proposed mechanism are consistent with the idea that modifications of LDL is the important factor, not LDL per se. However, since the majority of cholesterol LOWERING trials throughout the decades have failed to show any benefit, I fail to see the value in lowering cholesterol.
You neglect the fundamental fact that LDL injection itself causes artery disease in experimental models. Direct LDL injection results in aggregate increase in LDL-C.
"However, since the majority of cholesterol LOWERING trials throughout the decades have failed to show any benefit, I fail to see the value in lowering cholesterol".
LOL! Even if we accept this we ought to look things in bigger picture. Most lipid-lowering trials have been performed on high risk people with existing cardiovascular disease. The median age at the randomization in typical statin trial has been 63 and medium duration 5 years. Most of the trials have been performed using low potency statins. Drugs and moderate dietary modification can only have a very limited impact when adopted at later in midlife with pre-existing disease. Even though the plaques will be stabilized and even though high-potency statins can actually regress the plaques to some extent, still the plaques can cause a rupture and result in MI in people with pre-existing coronary artery disease.
Anyways, the degree to which LDL is lowered with statin corresponds linearly to the decreased risk of CHD events in people with pre-existing disease at are the late stages in their mid-life.
There are actually 3 such trials that I am aware of the tested the hypothesis that smoking cessation would lower the risk of lung cancer mortality. All 3 trials failed to produce statistically significant findings despite reporting significant reductions in smoking prevalence in the group that received counselling on smoking cessation. These trials include the Whitehall Study, the Lung Health Study, and MRFIT, which included in total over 20,000 participants and up to 20 years of follow-up. This makes these trials considerably larger in both in terms of participant size and length of follow-up than the trials that focused on replacing primarily saturated fats with polyunsaturated fats. The largest of these 3 trials found that the number of lung cancer deaths were actually 15% greater, albeit not statistically significant in the group that received counselling on smoking cessation.
http://onlinelibrary.wiley.com/doi/10.1002/1097-0142(20001201)89:11+%3C2422::AID-CNCR16%3E3.0.CO;2-E/full
The relative failure of these smoking cessations trials can be considered a very good example of why all forms of evidence need to be considered when evaluating a hypothesis, not just a few data points from a few randomized controlled trials. The lack of statistically significant favourable findings in the group that received counselling on smoking cessation has been explained by a lack of follow-up time sufficient to achieve the maximum benefits of smoking cessation (which is believed to be more than 2 decades), lack of participant size, a smaller than anticipated number of participants in the group that received counselling that quit smoking, and a greater than anticipated number in the group that did not receive counselling that quit smoking. These limitations are very similar to those that plague the trails that attempted to test the diet-heart hypothesis.
Genesis Land of Confusion...
http://www.youtube.com/watch?v=zU9lv_WqK6k
It's your stock in trade eh Dick? :-P
Ah the false analogy of smoking. The lipid hypothesis is in really bad shape if it needs to create all sorts of ad hoc hypotheses for its failures which it has been doing for decades! In any case, there are actually common factors to familial hypercholesterolemia and smoking which may explain the increased risk in both - oxidative stress.
What's really comical is the way you will simultaneously try to offer a trial as incontrovertible evidence (there is no such thing in science, by the way) in support of your position, while in the exact same breath, point out why so many of these same "trails" have been plagued (plaqued?) with limitations! ROFLOL
In much the same way as your tactic above "LOL! Even if we accept this we ought to look things in bigger picture." ...where the reader is left confused (bemused?) as to whether you do accept the point as potentially valid, or if you are simply LOL'ing at it.
It's all just fun and games to you... eh Dick? :-P
Saturated fat and dietary cholesterol both oxidizes LDL cholesterol, moreover, it has been demonstrated that macrophages are able to take up LDL particles even in their unmodified form.
http://www.ncbi.nlm.nih.gov/pubmed/20634472?dopt=Abstract&holdin...
http://www.youtube.com/watch?v=FXV4MEO5s_E&list=PLDBBB98ACA18EF67C
1) "The amount of LDL oxidized and the subsequent risk of CAD can also be affected by dietary factors other than antioxidants. Reducing saturated fat intake (Figure 1) lowers the plasma con- centration of LDL and thus the amount of LDL available for oxidative modification. Parks et al (1) achieved this by replacing fat in the diet with carbohydrates."
http://ajcn.nutrition.org/content/68/4/759.full.pdf
2) Dietary cholesterol increases the susceptibility of low density lipoprotein to oxidative modification.
3) Lowering dietary saturated fat and total fat reduces the oxidative susceptibility of LDL in healthy men and women.
Moreover, the results from the new study on children fed ketogenic diet are on par with other studies that have looked fatty acids and carotid thickness.
1) Consumption of omega-3 fatty acids is not associated with a reduction in carotid atherosclerosis: the Genetics of Coronary Artery Disease in Alaska Natives study
"Dietary intake of omega-3 FAs in a moderate-to-high range does not appear to be associated with reduced plaque, but is negatively associated with IMT. The presence and extent of carotid atherosclerosis among Eskimos is higher with increasing consumption of saturated FAs"
2) Dietary fat intake and carotid artery wall thickness: the Atherosclerosis Risk in Communities (ARIC) Study.
"Wall thickness was measured with B-mode ultrasound. After adjustment for age and energy intake, animal fat, saturated fat, monounsaturated fat, cholesterol, and Keys' score were positively related to wall thickness, while vegetable fat and polyunsaturated fat were inversely related to wall thickness. These associations persisted after further adjustment for smoking and hypertension and were consistent across the four race and sex groups. Thus, elements of habitual dietary intake were consistently associated with carotid artery wall thickness, compatible with their putatively atherogenic and antiatherogenic properties".,
http://www.ncbi.nlm.nih.gov/pubmed/8178786
Reducing saturated fat intake is associated with increased levels of LDL receptors on mononuclear cells in healthy men and women.
Lowering LDL does not do anything beneficial for the umpteenth time, so any explanation invoking lowering LDL is a poor one. It follows that IF oxldl is indeed the cause of disease then lowering LDL to achieve lowered oxldl seems like a poor strategy. Futhermore, oxldl and oxidative stress are not necessarily correlated with LDL and you're confusing oxldl with oxidative stress which is much broader in connotation.
I've already done a review on saturated fat - http://diettrialclaims.blogspot.com/2013/08/saturated-fat-and-inflamm...
ZM;
it's rather clear that you are ideologically opposed to any strategy that involves lowering LDL. The online is full ideologically motivated denialists like you who will tell you that Darwin manipulated his data or the climate change is a hoax created by Al Gore to suppress American global domination, etc. You are on par with these people! Often we get to read about these people when they are trying to blow up abortion clinics or detonate their local tax bureau.
"The State makes war on cholesterol because it is your best defense against that State: Cholesterol empowers independent thought by strengthening mental capabilities. In truth, to be anti-cholesterol is to be pro-State; to be anti-State – that, dear reader, is to be pro-cholesterol."
--Chris Masterjohn
Reply to comment #78 by DickK
http://archive.lewrockwell.com/orig6/masterjohn1.html
http://www.cholesterol-and-health.com/Cause-Of-Alzheimers.html
Masterjohn has lost his mind.
Surely you must realise by now DICK that you are wasting your time here? You are not impressing, nor convincing anyone with your games. You have zero credibility with the intelligent, skeptical, reasonable, free-thinkers who read this blog... and a great many other blogs besides; where it seems you elicit the same negative response and often end up banned -- just as you did recently at Denise Minger's blog, despite your attempts to reappear under another pseudonym. How pitiful is that?!?
Every time you try to detract from another's post, as you just did above, by suggesting that ZM is a closet bomber (hah!) you actually reveal more about your OWN tactics than anything else... you are showing us how YOU think and it is really not pretty, nor reasonable at all. You are a nasty, vile, obnoxious, dangerous, slimy, contemptuous waste of an individual.
I don't bother trying to engage you in reasonable discussion because with you it is JUST like trying to reason with a new-earth creationist, or a vegan zealot... there is NO room for reasonable discussion with people like you. You are either an ideologue yourself OR you are paid to pollute these blogs with your verbal diarrhoea.
It is just so obvious and so transparent, yet even when called out on trying to hide behind yet another pseudonym like "liam", you just plow right on regardless. People here are not idiots and yet you seem to think you can ride rough-shod over as if we are. YOU ARE WRONG.
charles grashow: "Masterjohn has lost his mind."
Hmm, do you realize that he has a comment section on that very Alzheimer's post? Why comment here that he has "lost his mind" when you can do so on his website?
Because the article was published in 2005 - I think it's a little too late for comments.
It's irrelevant when the article was published because the comment section is open. In fact, the comment section was opened recently: "Comments were enabled on June 17, 2013 - http://www.cholesterol-and-health.com/Cause-Of-Alzheimers.html"
So please, take the time to enlighten him.
http://shop.pomwonderful.com/pdf/clinical_nutrition.pdf
Pomegranate juice consumption for 3 years by patients with carotid artery stenosis reduces common carotid intima-media thickness, blood pressure and LDL oxidation
"Ten patients were supplemented with PJ for 1 year and five of them continued for up to 3 years. Blood samples were collected before treatment and during PJ consumption. In the control group that did not consume PJ, common carotid intima-media thickness (IMT) increased by 9% during 1 year, whereas, PJ consumption resulted in a significant IMTreduction, by up to 30%, after 1 year."
A very small study which showed benefits in the carotid arteries and in oxidative status despite no changes in LDL? Supports what I said before.
Roxanne W
Here is a link to a 38-minute video on YouTube of Dr. Westman speaking to a group of patients at the Duke Lifestyle Medicine Clinic in Durham, North Carolina, USA, about his "No Sugar, No Starch" program.
Here is a link to a 38-minute video on YouTube of Dr. Westman speaking to a group of patients at the Duke Lifestyle Medicine Clinic in Durham, North Carolina, USA, about his "No Sugar, No Starch" program:
http://www.youtube.com/watch?v=dSLf4bzAyOM
Replies: #88, #90
Reply to comment #87 by Roxanne W
"And if you lose page 4, I will send you another one. I have many page 4s."
http://onlinelibrary.wiley.com/doi/10.1111/j.1520-037X.2002.01231.x/full
The Effect of High-, Moderate-, and Low-Fat Diets on Weight Loss and Cardiovascular Disease Risk Factors
"One hundred men and women followed one of four dietary programs for 1 year: a moderate-fat (MF) program without calorie restriction (28 patients); a low-fat (LF) diet (phase I) (16 patients); a MF, calorie-controlled (phase II) diet (38 patients); and a high-fat (HF) diet (38 subjects). Weight, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglycerides (TG), homocysteine (Ho), and lipoprotein(a) [Lp(a)], were measured every 4th month. The TC/HDL-C ratio was calculated and fibrinogen levels were measured at baseline and after one year.
Dietary Regimens
High-Fat (HF) Diet This diet is defined as one in which patients consume 55%-65% of their daily caloric intake in the form of fat calories. Less than 100 g of carbohydrates (RCHO) were consumed daily and protein intake constituted 25%-30% of the total caloric intake. Patients ate until satiated.
Moderate-Fat (MF) Diet Patients following this dietary program consumed 20%-30% of their calories in the form of fat. Approximately 60% of their calories were from carbohydrate sources and the remaining calories were derived from protein. Patients consumed 10–12 calories per pound per day on this diet.
MF, Calorie-Controlled (Phase II) Diet Patients following this program were asked to consume 350–500 fewer kilocalories per day than required15,20 to maintain body weight. This was determined by multiplying their current weight in pounds by 10 kcal/lb to determine the required kcal intake per day; 350–500 was subtracted from this figure to determine the desired daily intake of calories. Of these calories, 15% were protein and 70% were carbohydrate, with an emphasis on complex carbohydrates vs. simple sugars. The remaining 15% of the calories could be consumed as fat in a 2:1 ratio of nonsaturated (polyunsaturated and monosaturated) to saturated fat, with no more than 5 g of saturated fat intake per day.
Low-Fat (LF) (Phase I) Diet The LF diet consisted of fruits, vegetables, a limited amount of grain/cereals for breakfast and a multiple vitamin that included 100% of the US Department of Agriculture recommended daily intake of vitamins and minerals. Patients ate until satiated. Of the caloric intake, 10% was fat, 15% was protein, and 75% was carbohydrate, with an emphasis on complex vs. simple carbohydrates as shown in Table I.
Each individual was instructed to exercise an average of 3–5 times per week, beginning with stretching for 15 minutes, followed by walking for 30 minutes, and then relaxing and stretching for an additional 15 minutes.
Patients returned on a monthly basis to review their progress, answer any questions regarding dietary habits, and determine if they were having any medical problems, which would require removal from the study. Weights were recorded at the beginning of the study and at the end of months 4, 8, and 12. Fasting venous blood was drawn at the beginning of the study and at the end of months 4, 8, and 12. The tests included total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDLC), triglycerides (TG), homocysteine, and Lp(a). The TC/HDL-C ratio was calculated for each of these intervals. Fibrinogen levels were measured at the beginning and end of the year.
Reductions in TC, LDL-C, TGs, and TC/HDL ratios were significant only in patients either following a LF diet or a MF, calorically reduced diet. Only patients following HF diets showed a worsening of each cardiovascular disease risk factor (LDL-C, TG, TC, HDL-C, TC/HDL ratio, Ho, Lp(a), and fibrinogen), despite achieving statistically significant weight loss."
Roxanne:
Thank you so much for that link. I hadn't seen that
video before.
It is the most calm, complete explanation of how to
go LCHF.
Gotta get ahold of page 4!
January 13 2014 1
"100 g of carbohydrates...daily" is not necessarily a low
carb diet.
Is the Ketogenic Diet good for someone who has non-alcoholic fatty liver?
Reply to comment #92 by Linda
Its probably the absolutly best diet for NAFLD!
"Curbing carbohydrates is more effective than cutting calories for individuals who want to quickly reduce the amount of fat in their liver...."
http://www.diabetesincontrol.com/index.php?option=com_content&vi...
"My Fatty Liver Is Gone"
http://www.dietdoctor.com/fatty-liver-gone


Matt joined Emma Turnbull Lawyers as a solicitor in 2017.
Following completion of an arts degree at Monash University, Matt commenced studying law in 2014. At that time he began working and volunteering in some of the countries busiest community legal centres, as well as working as a clerk in a conveyancing office. This experience gave Matt a sound insight into how the courts work, as well as the desire to bring about social justice through advocacy.
In his time pursuing a law degree at La Trobe University, Matt excelled in the study of Evidence and Criminal Procedure, which gave rise to a passion for the criminal law.
Matt has spent the last two years working at Refugee Legal, so has much experience with clients from socially and economically marginalised backgrounds, as well as those who have experienced past trauma.
While he advocates with authority, Matt understands the importance of strong professional relationships in the legal profession and court system.
Matt appears as an advocate in the Magistrates' Court for criminal matters, including plea hearings, bail applications, mention and contest mention hearings.
In addition, Matt is a member of the Law Institute of Victoria.


The British government has moved a step closer to deporting radical cleric Abu Qatada — a man authorities say has served as the spiritual guide to 9/11 hijacker leader Mohammed Atta and authorized the killing of Jewish children — following Jordan's official publication of a treaty barring evidence obtained through torture from being used against him at a retrial on terror charges.
The agreement has now been ratified by both houses of the Jordanian parliament, approved by King Abdullah, and published in the Hashemite government's official gazette, Britain's Guardian newspaper reported Tuesday. The British parliamentary scrutiny process has been completed as well.
"While further steps remain, our focus is on seeing Abu Qatada on a plane to Jordan at the earliest opportunity," British Security Minister James Brokenshire said.
Qatada, a native of the West Bank town of Bethlehem, was convicted in Jordan in 1999 and 2000 on terror-related charges including participation in the thwarted "millennium plot" to attack Western and Israeli targets in Jordan on Dec. 31, 1999.
British authorities said he has also had links to Ayman al-Zawahiri, al-Qaida's current leader, and to the al-Tawhid movement led by Abu Musab Zarqawi, whose Iraq-based group beheaded British civil engineer Kenneth Bigley after kidnapping him in Baghdad in 2004.
Videos of Qatada's sermons were reportedly found in Atta's Hamburg, Germany apartment, and three days after 9/11 Qatada called the hijackings a response to America's unjust policies.
In an October 1999 speech, "he effectively issued a fatwa authorizing the killing of Jews, including Jewish children," according to the British government's case against him, and said Americans everywhere should be attacked.
Since 2002, he has spent most of his time behind bars pursuant to British immigration and anti-terror laws. Freed on bail in 2008, Qatada went back to prison after violating restrictions on his use of mobile phones and other communication devices.


Training was fairly rudimentary as, no matter how much they can tell you, you really learn on the job. I made a few rookie mistakes, but all in all think I did pretty well. My time slot is 9-11 on Tuesday mornings, prime time on off campus radio, but a bit of a graveyard slot at Uni!
I started off the show with Maggie May, as that was number 1 when I arrived, and ran through a Playlist of 32 songs as varied as Pretty Vacant, Baker Street, All the Young Dudes and Hot Stuff. I finished off with Simple Twist of Fate by Big Bob in recognition of his Nobel Prize!
You're right about 9-11 being dead time at University. My son's hall of residence flat has a notice saying please, no noise before 11 in the morning. Get up you lazy layabouts!


When Michael Dourson, Trump's nominee to head EPA's chemical safety office, was grilled by the Senate Environment and Public Works Committee earlier this month, I sat in the hearing room thinking about what, exactly, was at stake. Next to me were families who had traveled to DC from Indiana because their groundwater is contaminated with TCE, an industrial solvent linked to cancer. One of those families has a child in treatment for cancer. Another lost their child to cancer.
Last year, with your help, Congress—with rare bipartisan spirit—passed a law to better regulate toxic chemicals. That law is meant to protect children from chemical exposures that may cause cancer. It should go without saying—but not these days: The bill must be implemented by someone who wants to protect children's health.
Dourson has built his career as a consultant for chemical companies. Paid by the chemical industry, he has dangerously downplayed the health risks of TCE, the carcinogen that contaminated groundwater in Indiana and many other states; 1,4-dioxane, established by scientists and medical researchers to be a likely carcinogen; flame retardants; and PFOA, a stain resistant chemical made by DuPont that harms the developing brains of babies and children.
PFOA has contaminated water supplies in New York, Ohio, and West Virginia. In West Virginia, Dourson helped the state environmental protection department set a safety level for PFOA that was 150 times higher than the maximum level DuPont's own scientists had set. This standard, more than 2,000 times less stringent than the one the EPA now recommends, stayed in place for four years, and determined which families DuPont was required to supply with clean water.
For decades, if you were a big company facing health challenges from EPA, you knew just what to do: Ask Dourson for a review of your toxic product. What you would get in return: A recommendation that the government weaken health standards for that chemical.
In the Senate hearing room, I was shocked at Dourson's reluctance to acknowledge the health harms of a range toxins, from petcoke to PFOA. He also boldly refused to recuse himself from deliberations about the very chemicals he has been paid to champion. Watching the emotional reaction of those families next to me was physically painful.
Let's get one thing straight. When moms talk about protecting children from chemical exposures, we are talking about cancer, birth defects, and other devastating issues.
Dourson has built a career supporting industry polluters. He has worked for Dow Chemical, Koch Industries, DuPont, and Chevron to whitewash the impact of chemicals linked to a range of health problems.
Dourson even took money from Big Tobacco to downplay the health effects of breathing second hand cigarette smoke.
This is the wrong guy for the job.


text:
BT: Union Bank classifies Suzlon Energy's loan account as NPA; other banks may follow suit
22 July 2019: Wind turbine major Suzlon Energy Ltd's financial woes continue to mount. A week after defaulting on the payment of outstanding bonds worth Rs 1,182 crore, its loan account with the Union Bank of India has been classified… Read More ›
LM: More banks likely to have been singed by Bhushan Power fraud
By rsqresearch on July 8, 2019 • ( 0 )
8 July 2019: More lenders to bankrupt Bhushan Power and Steel Ltd may say that the company misappropriated funds given to it after state-run Punjab National Bank first reported a ₹3,800 crore fraud, a top bank official said, requesting anonymity…. Read More ›
LM: PNB reports over ₹3800 crore fraud by Bhushan Power & Steel
6 July 2019: Punjab National Bank on Saturday said it has detected a fraud of ₹3,805.15 crore by Bhushan Power & Steel Ltd and has reported it to the Reserve Bank of India. The exposure of ₹3,800 crore includes domestic… Read More ›
LM: Bank of Baroda buys ₹3,000 crore DHFL loans
By rsqresearch on June 30, 2019 • ( 0 )
30 June 2019: Bank of Baroda (BoB) has entered into a transaction with Dewan Housing Finance Corp. Ltd (DHFL) to acquire loans worth ₹3,000 crore against its exposure to the non-bank lender, even as a lenders' consortium to the stressed… Read More ›
BT: Lenders approve JSW Steel's bid to acquire stressed ACCL for Rs 1,500 crore
30 June 2019: The SBI-led committee of creditors of Asian Colour Coated Ispat Ltd (ACCL), which has an outstanding debt of over Rs 5,000 crore, has approved JSW Steel's Rs 1,500-crore bid to acquire the stressed steel company. Most of… Read More ›
BS: NCLT approves okays Dhanuka Laboratories' resolution plan for Orchid Pharma
25 June 2019: The Chennai bench of the National Company Law Tribunal (NCLT) has approved Dhanuka Laboratories', resolution plan for the debt-ridden Orchid Pharma. The Tribunal has rejected a move against the plan filed by Accord Life Spec, another resolution… Read More ›
BS: Ready to revise resolution plan for Orchid Pharma: Accord to NCLT
19 June 2019: With the National Company Law Tribunal (NCLT) yet to decide on Dhanuka Laboratories' resolution plan for Orchid Pharma's insolvency process, Chennai-based Accord Life Spec Pvt Ltd on Wednesday told the tribunal that it was ready to revise… Read More ›
LM: India Ratings downgrades PNB's ₹6,750-crore AT1 bonds
18 June 2019: India Ratings and Research (Ind-Ra) has downgraded Punjab National Bank's additional tier I (AT1) perpetual bonds worth ₹6,750 crore by one notch to A/negative outlook from A /negative. However, the rating agency has affirmed the bank's overall… Read More ›
LM: PNB puts on block 6 NPAs with outstanding of over ₹1,000 crore
17 June 2019: State-owned Punjab National Bank (PNB) has put on sale six non-performing loans amounting to over ₹1,000 crore, including two accounts of Vandana Vidyut and Visa Steel. Asset reconstruction companies (ARCs), non-banking financial companies (NBFCs), other banks and… Read More ›
TOI: PNB's dissent hits Dhanuka's bid for Orchid
13 June 2019: A last-minute change by Punjab National Bank (PNB) after voting in favour of and suddenly reversing its decision has turned the acquisition of beleaguered Orchid Pharma by Dhanuka Labs into a cliffhanger. PNB is one of the… Read More ›

redpajama_set_name: RedPajamaCommonCrawl


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This bag is equipped with a flap and a delicate chain, which can be adjusted to carry for any occasion. Long and off the shoulder, for a sophisticated look. Or short, for a casuallook. MADEMOISELLE LONGCHAMP, chic style coupled with an uninhibited French allure.
Elusive, a traveller at heart, her chic allure will take her both to the end of the street and the end of the world. She is bold enough to reinvent her life, to create her own codes. MADEMOISELLE LONGCHAMP embodies this French spirit, often worn where it's least expected, including in terms of style.
Its signature is an iconic clasp, and the details on its shoulder strap and the enamelled wax seal give the line character.
Playing with the codes of MADEMOISELLE LONGCHAMP, the perforations have been replaced here with small rounded studs, giving the elegant, understated calfskin a rock twist.


Green fluorescent protein (GFP) is found in a jellyfish that lives in the cold waters of the north Pacific. The jellyfish contains a bioluminescent protein--aequorin--that emits blue light. GFP converts this to green light, which is what we actually see when the jellyfish lights up.
GFP's protein chain forms a cylindrical can, with one portion of the strand threading straight through the middle. The specific part responsible for GFPs fluorescence, called the chromophore, is shielded in the middle of the can. Jostling water molecules would normally rob the chromophore of its energy once it absorbs a photon. But it is protected inside the protein, releasing the energy instead as a slightly less energetic photon of light. The chromophore forms spontaneously from three amino acids in the protein chain: a glycine, a tyrosine and a threonine (or serine).
To build paper model of Green fluorescent protein, download and print the template PDF. Instructions for cutting and assembling are included.
Use the PDB-101 Browser to explore more resources and articles related to Biotechnology.
Crystal structure of the Aequorea victoria green fluorescent protein.
M. Ormo, A.B. Cubitt, K. Kallio, L.A. Gross, R.Y. Tsien, S.J. Remington.


Believe or not, your disposition plays a huge part in the success of your workout journey. It's probably one of the reasons you enjoy that Zumba class alone so much more than a Yoga session with your friends. Research has shown that our personality, and even mood can dictate what we enjoy.
Fortunately, there are as many workouts as there are personality types, which makes it easy to find a training style that fits your lifestyle.
Gavin has spent a majority of his career researching the overlap between activity and personality, and while data isn't set-in-stone, there are ways to assess the best workout for someone's personality. Some of which depends on personal preference and stress response.
Basically, a higher BAS score indicates that the person is more motivated by reward — such as winning a race. Whereas, a lower BIS score means you'd be more motivated to avoid punishment. So, a person with a lower BIS score is sensitive to negative feelings, such as sweating, breathing hard and increased heart rate.
In short: how you're wired defines how you view your workout.
Like research has stated, there's no specific answer. But, there are a couple of general guidelines you can follow to implement the best regimen based on personality.
Exercise for you is to clear your head. Scientists recommend activities like endurance sports (swimming, running, cycling), one-on-one personal training, golf, or mind-body focused workouts like yoga and pilates. These workouts are more process oriented, wherein, you focus on bettering yourself each day — it allows introverts to feel comfortable.
High-intensity workouts are your best bet. Zumba, sprinting, weightlifting — it's all good. Fitness meetups like hiking and trekking, yoga in the park and team sports are also viable options for the social person.
But, there are always going to be exceptions to this rule. An extrovert may enjoy solitude by putting on headphones and jogging in the middle of the night. "An individual's specific intention for his or her workout may lead them to fall outside the basic parameters", says Jessica Matthews, senior advisor for the American Council on Exercise.
Regardless, the world is your oyster. Now go out there and enjoy working out!


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A Subsidized Vending Program can be created to your specifications so that the employee can purchase products at a discounted rate while the company subsidizes the remaining costs. Though this option would be at a greater expense to the company, there is no doubt that it would be a well-regarded perk by your employees and improve your corporate moral.
With a "Free Vending Plan", your company would pay for all products provided my Canteen Service of Northern California and your employees would benefit from access at no personal cost. There is no doubt that your employees would have great incentive to stay within your facilities throughout the work day when they can access a selection of quality brand name products within the work environment.
Contact our sales department at mvonhaus@canteensr.com to create a personalized vending program that is right for you. Our free consultation will help you understand all the options available to you.


Jewelry is a wonderful way to express feelings, whether it be to celebrate an achievement, or to show your love and pride. Even the most delicate pieces of jewelry are special gifts that will be appreciated by their recipient. The following article will give you some insight about jewelry, whether you are thinking of buying some as a gift or purchasing a special piece for yourself.
TIP! Be careful on how you store all of your jewelry together. Jewelry should be stored in an organized way in a box, a jewelry holder or hung on hooks.
Be careful when storing all your jewelry together. Consider delegating each piece to its own resting place, utilizing compartmental boxes and storage units. Resist the urge to jumble all your pieces together in one box or basket. Not only will your necklaces become hopelessly tangled, you risk harming any fragile pieces as they bump and scrape against each other as you search the box.
Do some price comparisons before you commit to buying a piece of diamond jewelry. Look at the pieces up close before purchasing them, and be sure to compare them to others. Don't fall for any of the tricks used by shady dealers. They employ these tactics to make a diamond look better than it really is.
TIP! To distinguish between real and fake, bring a magnet when you shop for sterling silver jewelry. Take the magnet with you to find fake pieces of jewelery, sterling silver will not stick to the magnet.
Before you buy any new jewelry, you should look around for the latest trends. It is one thing to get a gorgeous bauble, but it is another to get it on sale!
Check to see if your jeweler offers an insurance policy before purchasing an item. Many stores offer a policy where you can bring broken or damaged jewelry back to the original jeweler for repair at little to no cost. Some jewelers have insurance policies that cover lost of stolen jewelry, also.
TIP! Before you make a final jewelry-buying decision, take a look at what's new and trendy. Price a variety of similar items before buying an expensive piece.
If you wish to keep a piece of jewelry looking fantastic, preventing it from tarnishing is important. Keep your jewelry away from water. Exposure can result in tarnishing, rusting or dulling of different metals. If you must take your jewelry somewhere wet, prepare it by adding some clear nail polish on the surface.
Taking proper care of your jewelry requires careful consideration. Every metal, setting, and stone has different requirements when it comes to care. Each piece is individual in its needs so don't assume what works well for one piece will work well for all. Ask a jeweler when you do not know how to take care of your jewelry.
TIP! Always check with your jeweler about insurance policy options before buying anything. In the unfortunate, but possible event that your jewelry gets damaged, the jeweler will be able to replace or fix it for you.
Consider unique pieces of jewelry for unique individuals. This shows that you are both thoughtful and creative, traits that someone who would want a unique piece of jewelry is likely to value.
Accent a belt with a brooch to add more visual interest instantly. Either put it near your hip or near the middle of your waist.
TIP! Preventing tarnish will keep your jewelry look its best. Don't take your jewelry into the water, regardless of whether you are showering or hitting the beach.
As you surely know by now, jewelry is appropriate for so many different kinds of occasions and events. Even the smallest piece can mean a lot to the one receiving it. There are things you should know about how to take care of your own jewelry, too. No matter what, follow these suggestions to get more joy from jewelry.
Click on right here for more data.


text:
Home Local Unemployment claims fall below pre-pandemic levels
Unemployment claims fall below pre-pandemic levels
by The Center Square November 25, 2021 0 comment
By CASEY HARPER
THE CENTER SQUARE SENIOR REPORTER
(The Center Square) — New federal jobs data shows the number of first-time filers for unemployment benefits dropped to the lowest level in decades.
The U.S. Department of Labor released unemployment numbers Wednesday, showing new unemployment claims fell by 71,000 last week. Wednesday's report marked the first time weekly unemployment claims have been better than pre-COVID-19-pandemic levels.
"In the week ending Nov. 20, the advance figure for seasonally adjusted initial claims was 199,000, a decrease of 71,000 from the previous week's revised level," DOL said. "This is the lowest level for initial claims since Nov. 15, 1969 when it was 197,000. The previous week's level was revised up by 2,000 from 268,000 to 270,000.
"The four-week moving average was 252,250, a decrease of 21,000 from the previous week's revised average. This is the lowest level for this average since March 14, 2020 when it was 225,500."
The number of ongoing unemployment claims and overall unemployment, though, still remain higher than levels before the pandemic.
"The total number of continued weeks claimed for benefits in all programs for the week ending Nov. 6 was 2,432,281, a decrease of 752,390 from the previous week," DOL said. "There were 21,111,266 weekly claims filed for benefits in all programs in the comparable week in 2020. "
The number of unemployment claims varied across states.
"The highest insured unemployment rates in the week ending Nov. 6 were in the Virgin Islands (3.0), Alaska (2.7), District of Columbia (2.7), Puerto Rico (2.7), California (2.6), New Jersey (2.5), Hawaii (2.1), Nevada (2.1), Illinois (1.9), and New York (1.8)," DOL said. "The largest increases in initial claims for the week ending November 13 were in California (+4,690), Massachusetts (+2,269), Pennsylvania (+1,994), Minnesota (+1,202), and Wisconsin (+907), while the largest decreases were in Kentucky (-8,712), Tennessee (-4,001), Ohio (-3,315), Michigan (-3,230), and Illinois (-1,184)."
President Joe Biden has touted job creation since he took office and celebrated the federal data Wednesday.
"This is a historic jobs recovery: 5.6 million jobs created since I took office and an unemployment rate of 4.6% two full years earlier than experts predicted was possible," President Biden said.
Critics, though, have said Republican governors in red states have led the way in the economic recovery. Red states reduced lockdown measures faster and many refused federal unemployment benefits, which they argued were incentivizing Americans to turn down job opportunities.
"The top 10 states for jobs recovered since the pandemic began and the lowest unemployment rate are all led by Republicans!" Republican National Committee Chair Ronna McDaniel touted on Twitter.
Republicans also point to other economic problems, such as inflation, which has risen at the fastest rate in decades alongside a significant increase in federal spending.
"Pretty much the only American not concerned about inflation is Joe Biden, whose policies are causing it," Sen. Josh Hawley, R-Mo., said.
Casey Harper works at The Center Square's Washington, D.C., bureau.
Alma Rosa
Jury in Georgia finds 3 men guilty in Arbery killing


text:
Blog Article List
President Ramaphosa's 2019 State of the Nation Address
Sam Smith Blog 01 March 2019
01 Mar 2019~ Gerhard Erasmus
Photo credit: Alexandros Michailidis | Shutterstock.com
A State of the Nation Address (SONA) is not like a formal contract, especially not in an election year. It cannot be "enforced". But the one delivered by President Ramaphosa on 7 February 2019 came at a crucial moment. The South African economy is in an unhealthy state, while the revelations (by several commissions of enquiry) about the extent of the corruption, mismanagement and damage under the presidency of Jacob Zuma paint a dark and worrying picture. South Africa needs a bold rescue package under a firm hand.
In tralac's February Newsletter we highlight the most important themes in the SONA 2019 and we ask specific questions: What are the main concerns and what areas are being identified as priorities? What are the plans for addressing them? How will they be implemented? How has this State of the Nation address been received?
We also add a brief discussion of the national budget, delivered on 20 February 2019. This is the reality check against which many of the promises in SONA should ultimately be read.
SONA 2019 is built around certain themes:
Firstly, we must accelerate inclusive economic growth and create jobs.
Secondly, our history demands that we should improve the education system and develop the skills that we need now and into the future.
Thirdly, we are duty bound to improve the conditions of life for all South Africans, especially the poor
Fourthly, we have no choice but to step up the fight against corruption and state capture.
Fifthly, we need to strengthen the capacity of the state to address the needs of the people.
It is election time in South Africa. In May this year the nation goes to the polls, for the first time under the leadership of President Rampahosa, who is also the leader of the governing party. The ANC has been ruling South Africa for 25 years now and the track record is not impressive. It now faces the additional challenges of internal divisions and the legacy of Jacob Zuma. This election will be a benchmark for President Ramaphosa's support in the ANC and will show how much leeway he has for taking unpopular but necessary measures to improve competitiveness and to reform most State-owned Enterprises.
The changing multilateral system poses another test for the Government. As stated: "Unless we adapt, unless we understand the nature of the profound change that is reshaping our world, and unless we readily embrace the opportunities it presents, the promise of our nation's birth will forever remain unfulfilled."
To this must be added policy uncertainty, mismanagement and corruption. "We have also had to deal with the effects of state capture on vital public institutions, including our law enforcement agencies, whose integrity and ability to fulfill their mandate had been eroded in recent years."
He recognizes that "the levels of growth needed to make significant gains in job creation will not be possible without massive new investment. Last year, our economy was confronted by the reality of a technical recession."
The President has several other bold plans:
The World Bank's annual Doing Business Report currently ranks South Africa 82 out of 190 countries tracked. "We have set ourselves the target of being among the top 50 global performers within the next 3 years."
"Over the next six years, we will provide every school child in South Africa with digital workbooks and textbooks on a tablet device."
There will be free higher education for qualifying first year students.
The mantle of power rests uneasily on the shoulders of President Ramaphosa. Since coming to office, he has tip-toed cautiously in some areas. But he has delivered a clear message, perhaps most notably to the international community, and has started to address the litany of challenges. A notable example is his firing of Tom Moyane, Commissioner of the South African Revenue Service (SARS), on 1 November 2018. During Moyane's tenure, SARS had become a key cog in the wheels of state capture, and its capacity to collect revenue was effectively decimated.
The process of rebuilding, what was once a model institution, has begun, but the devastating effects are clear in the 2019 Budget. The Minister of Finance had to revise down the estimate of revenue collection that he had presented in his mid-term budget statement in October 2018 by R15.4 billion. A legacy of failure and mismanagement at SARS has resulted in the Government expecting a shortfall by almost R43 billion for the current fiscal year.
SONA is ambitious and comprehensive but it's a first step only. Well-designed action plans, resources and a long-term vision are required. Support by the private sector, investors, and the citizens too will be necessary for turning South Africa around.
Ultimately, the record of the South African Government will be judged by results. Success depends on concrete steps, the honesty and resolve with which challenges will be tackled, and the selection of priority areas. The remedial action required for making South Africa a success will not happen overnight. And it will depend on many factors working out for us. The new dawn is still some time away.
Tags Trade governance Finance and developmentBusiness regulation
By Gerhard Erasmus
Gerhard Erasmus
Gerhard Erasmus is a founder of tralac and Professor Emeritus (Law Faculty), University of Stellenbosch. He holds degrees from the University of the Free State, Bloemfontein (B.Iuris, LL.B), Leiden in the Netherlands (LLD) and a Master's from the Fletcher School of Law and Diplomacy. He has consulted for governments, the private sector and regional organisations in southern Africa. He has also been involved in the drafting of the South African and Namibian constitutions. He grew up in Namibia.
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Trade Remedies in the African Trade Governance Context
The AfCFTA Dispute Settlement Mechanism as part of a continental Trade Regime
South Africa's Twin Peaks model looks strong but needs more independence
tralacBlog is a forum for the views of Trade Law Centre researchers and Associates, as well as guest contributors, on pressing regional integration and trade policy issues affecting African countries.
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The AfCFTA and continental Integration: What role for Women?
Gerhard Erasmus | 25 Jan 2023
AfCFTA Institutional Arrangements will impact on the interests of Women
What protection for Women under the AfCFTA Dispute Settlement Protocol?


She doesn't want to collect them, though. She'd rather watch them pop! Can you help her out in this weird and wild match 3 puzzle game?
TenTrix is easy to play and pleasurable game for all age.
Algerian Solitaire is the new solitaire game for everybody!
Become a Nail Doctor in few steps in gaming world.
2020 Connect is the most addictive logic puzzle you've ever seen!
Welcome to Bike Racing the most addictive racing game!
2020! Tetra is the latest and greatest version of the famous puzzle game Tetris.
Hexa Fever is a highly addictive strategic puzzle game.
Swipe bubbles to pop them and reach the popping target.
Paint the paths and fill the empty shapes!
Get ready for the 2016 Euro Cup with this wild game that mixes soccer with pachinko.
All of these beautiful butterflies are mixed up!
Compete across multiple continents as you race in the Grand Prix Series.


Operation Gateway - the operation launched after an ultimatum to investors and overstayers to sort all the required paperwork with the Department of Immigration (DOI) and Department of Labour (DOL) has raked in over Vt3 million(US$281,000) into Vanuatu Government coffers.
But the Gateway Operation Team is facing another threat – interference from politicians.
"I want to ask all Members of Parliament to stay out of the operation," said Minister of Internal Affairs, Andrew Napuat.
"Do not assist or put pressure on the officers in the departments engaged in the operation to grant visas when the foreigners do not meet visa requirements or work permits.
"I ask all politicians to stay out of this. Whoever is trying to assist foreigners bypass this process, know that this ministry will not tolerate it. The laws are there, all concerned should just follow the law, comply with the requirements and submit their applications.
"Anyone caught trying to assist foreigners bypass our laws and get involve in corruption will be dealt with.
During the initial announcement of the operation in February, records from the Ministry of Internal Affairs put the number of overstayers in the country at 600.
"They were given three weeks to come forward and sort their papers, and some of them have done this, Minister Napuat told Daily Post.
"Operation Gateway was launched on the 19th of March. So far, the fines and penalties paid by over 200 individuals to Labour and Immigration just last week has totaled up to Vt3 million.
A 28-man team from the DOI, DOL, Vanuatu Investment Promotion Authority, Foreign Affairs, Customs and Police kick started the Gateway Operation in Port Vila.
Minister Napuat said the Vanuatu National Provident Fund is also working with the team, to ensure the Minimum Wage aspect is being enforced.
The operation clamps down on overstayers and people who breached visa requirements. For example, coming to Vanuatu on a tourist visa but currently working and those who come in as investors, set up businesses for a short while and then move to work for other people without notifying the authorities.
Minister Napuat says the operation will run for three to four weeks.
"A18-man team is in Santo this week," he said.
The minister also mentioned the possibility of extending the operation in Port Vila.


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SPEED STROKE release details of "Scene Of The Crime"
Street Symphonies Records & Burning Minds Music Group are excited to announce all the details of "Scene Of The Crime", new official studio album by hard/sleaze rockers, Speed Stroke.
Speed Stroke are five guys who share a common passion for the golden times of rock and roll, when the music was played by true rockstars. Founded in Italy in 2010, the band was introduced to the international rock scene in 2011 thanks to their involvement in "Reborn In Sleaze", an official tribute album released in memory of Dave Lepard (Crashdïet). In March 2013 the band launched its S/T debut album, followed by "Fury" in 2016. Thanks to the deal signed with Bagana Rock Agency, Speed Stroke had the chance to promote their work all around Italy and abroad, sharing the stage with artists such as Reckless Love, Backyard Babies, Hardcore Superstar, Gotthard, Phil Campbell, Crazy Lixx, The 69 Eyes, Steel Panther, Santa Cruz, The Cruel Intentions, Shameless/Tuff, Sister, Tigertailz, Kissin' Dynamite and Confess.
Their explosive shows, filled with high-octane energy, passion, and excitement, contributed to the creation of a strong fanbase, especially in their home country. A key ingredient of their gigs is their natural ability to interact with an audience.
The title of the new album, "Scene Of The Crime", tells a lot about the band's sound and attitude: when the five pieces combo is around, on-stage or backstage, something epic is always expected to happen! With a more varied and mature sound, but still inspired by their childhood heroes, they turned their classic style into a 21st-century hard rock album, with a strong focus on the good melodies, undoubtedly their best so far. Definitely, Speed Stroke are back with a bang!
Mixed by Marco Paradisi & D.B. at Boat Studio (Bologna, Italy) and mastered by Giovanni Versari at La Maestà Mastering (Grammy winner for his work on the album "Drones" by Muse), "Scene Of The Crime" is scheduled for release on November 6, 2020, via Street Symphonies Records / Burning Minds Music Group. A special personalized edition, created by Outward Styles in a very limited quantity of 50 copies, will be available exclusively on the label's online shop in October. The cover art has been designed by SoloMacello (Black Veil Brides, Nick Oliveri, Elvenking, Band Of Spice, Valient Thorr), while the CD booklet features introductory liner notes written by renowned journalist Fabio Magliano (Metal Hammer Italy).
A dedicated Japanese version, which includes the exclusive bonus track "Drive Me Crazy", will be released instead via Spiritual Beast / Universal Music. Pre-orders are open at this link:
https://spiritual-beast.shop.
The vinyl version will follow later on the band's official website.
A lyric video for the first single "Who Fkd Who" is online at the following link:
1. Heartbeat
2. Scene Of The Crime
3. After Dark
4. Soul Punx
5. No Love
6. Red Eyes
7. Out Of Money
8. Who Fkd Who
9. One Last Day
10. Hero No.1
Jack: Vocals
D.B.: Lead Guitar
Michael: Rhythm Guitar
Fungo: Bass
Andrew: Drums
Italian Tour 2021 (supporting Reckless Love):
March 25, 2021, Slaughter Club, Paderno Dugnano, Milan, Italy
March 26, 2021, Revolver Club, San Donà di Piave, Venice, Italy
March 27, 2021, Alchemica Music Club, Bologna, Italy


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Correction: Summer Food Service Program 7 CFR Part 225
Federal Register link
In Title 7 of the Code of Federal Regulations, parts 210 to 299, revised as of Jan. 1, 2000, make the following corrections to § 225.6:
On page 131, first column, add the following text to the end of paragraph (b)(1):
PART 225—[CORRECTED]
§ 225.6
State agency responsibilities.
(b) * * *
(1) * * * Sponsors applying for participation in the program due to an unanticipated school closure during the period from October through April (or at any time of the year in an area with a continuous school calendar) shall be exempt from the application submission deadline.
2. On page 134, beginning in the second column, paragraphs (c)(4)(i), (ii) and (B) are corrected to read as follows:
(c) * * *
(4) Free meal policy statement.
(i) Each applicant must submit a statement of nondiscrimination in its policy for serving meals to children. The statement must consist of an assurance that all children are served the same meals and that there is no discrimination in the course of the food service. A school sponsor must submit the policy statement only once, with the initial application to participate as a sponsor. However, if there is a substantive change in the school's free and reduced price policy, a revised policy statement must be provided at the State agency's request. In addition to the policy of service/nondiscrimination statement described in paragraph (c)(3) of this section, all applicants except camps must include a statement that the meals served are free at all sites.
(ii) In addition to the policy of service/nondiscrimination statement described in paragraph (c)(3) of this section, all applicants that are camps that charge separately for meals must include the following:
(A) * * *
(B) A description of the method or methods to be used in accepting applications from families for Program meals. Such methods must ensure that households are permitted to apply on behalf of children who are members of households receiving food stamp, FDPIR, or TANF benefits using the categorical eligibility procedures described in § 225.15(f);


You are here: Home / Creatine / Naturo Nitro Creatine Chrome Review – Warning: Choking Hazard.
Creatine in powder form is as standard and traditional as it can get. The problem is powders are pretty bulky and sometimes causes stomach upsets or bloating when it comes to creatine. All for gains, right?
Good thing the folks at Naturo Nitro created a creatine supplement that comes in capsules and it's called Creatine Chrome.
It seems to solve a lot of problems but will it be as good or better than powder? Let's go check it out!
No loading phase: The loading phase serves to fill the body's creatine stores and requires time so eliminating this phase sounds exciting to say the least.
No more side effects? No bloating, cramping, and dehydration? Wow, really? Sounds awesome if it were true.
MagnaPower is good: Gotta give them a hand for using a premium form of creatine.
Directions for use: As a dietary supplement, take 3 capsules prior to exercise with an 8 oz glass of water.
Creatine MagnaPower™. This is a premium form of creatine created to not just get more creatine in your body but to also prevent it from being broken down to creatinine. Research says it's just as good as the current industry leader: Creatine Monohydrate.
Naturo Nitro Creatine Chrome wants us to get the most out of creatine so they turned it to capsules. Encapsulation works when it comes to maximizing absorption and removing a few side effects associated with powder supplements but we're not so sure if it's a bright move when it comes to creatine.
Okay so they removed a few factors: No more measuring since each serving is preweighed, no more awful taste, no more use of colors and other additives for powders. It should also lessen the chances of bloating or choking on undissolved powder.
Granted all those perks are good to go, the serving size is the deal breaker. Three capsules per serving is barely 2 grams and most users are WAY past that dosage.
We're talking about users who take at least 5-6 grams of creatine which mean they'll have to swallow nine capsules per day and let me tell you, a lot of people don't like stuffing their faces with capsules day in and day out. Not to mention how encapsulating costs more than giving it in powder form thus making the product more expensive per gram.
The only way this would work is if the user is past the loading phase (yes, we need the loading phase) and is around 200 lbs., the weight where 2 grams of creatine is good enough for the maintenance phase.
So are we calling Naturo Nitro Creatine Chrome a BS product? Nope. It works and probably is absorbed better than other powdered forms as far as we know. What we just don't like is how you'll be forced to swallow lots of capsules where one scoop would've been more than enough.
On top of the perks on creatine use, we also think it's good for maximizing absorption as well as preventing the bloats.
We're not sure about its "no loading phase" needed claim so we'll have to say users past that stage are its primary market, specially lifters who just can't take the bloating anymore.
If you take more than one serving, you're more likely to burden your gut with creatine powder anyway. Reducing the odds of bloating is not outright eliminating it so this is still pretty possible, folks.
Premium creatine. MagnaPower is a recognizable name anywhere.
Stackable. It's a one-ingredient formula.
Capsules. Much more convenient than powder.
Reduced bloats. Yep, we think so too.
Clean label. Nothing unnecessary included.
Expensive. Easily twice the price of most powders.
Short lifespan. 90 capsules ain't enough for a month.
Naturo Nitro Creatine Chrome is definitely a functioning creatine supplement. It does what creatine is supposed to and more. We recommend it for users who just can't stand bloating or looking for some sort of portability with their creatine. It's definitely not for those who not only hate capsules but also don't like the idea of spending money on one creatine bottle when they could buy two.


ivifocus added the Lindberg AH-1S Cobra (1:48) to his stash.
ivifocus added the MiniWorld M134 Minigun (Early) barrels (2 pieces) (1:48) to his stash.
ivifocus added the AMP Hughes OH-6A Cayuse (1:48) to his stash.
ivifocus added the MikroMir OH-6A Loach (1:48) to his stash.
ivifocus added the Heller Spitfire Mk XVI (1:72) to his completed kits.
ivifocus added the Academy P-40B (1:72) to his completed kits.
ivifocus just joined this community.
ivifocus Hello to Everyone! Glad to be here.
ivifocus added the Print Scale OH-58 "Kiowa" (1:48) to his stash.
ivifocus added the Microscale AH-1Gs and UH-1Cs (1:48) to his stash.
ivifocus changed his profile picture.


text:
Home > Physiology and Medical Physics > Physiology and Medical Physics Articles > 113
Physiology and Medical Physics Articles
Erratum to: Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer.
Deborah Ryan, Royal College of Surgeons in Ireland
Steven Carberry, Royal College of Surgeons in IrelandFollow
Áine C. Murphy, Royal College of Surgeons in IrelandFollow
Andreas U. Lindner, Royal College of Surgeons in IrelandFollow
Joanna Fay, Royal College of Surgeons in IrelandFollow
Suzanne Hector, Royal College of Surgeons in Ireland
Niamh McCawley, Royal College of Surgeons in IrelandFollow
Orna Bacon, Royal College of Surgeons in IrelandFollow
Caoimhín G. Concannon, Royal College of Surgeons in IrelandFollow
Elaine W. Kay, Royal College of Surgeons in IrelandFollow
Deborah A. McNamara, Royal College of Surgeons in IrelandFollow
Jochen HM Prehn, Royal College of Surgeons in IrelandFollow
Colorectal cancer, ER Stress, Calnexin, GRP78, GRP94, UPR (unfolded protein response)
Funder/Sponsor
Health Research Board. Science Foundation Ireland. European Union
The original article is available at www.biomedcentral.com
Physics | Physiology
Ryan D, Carberry S, Murphy ÁC, Lindner AU, Fay J, Hector S, McCawley N, Bacon O, Concannon CG, Kay EW, McNamara DA, Prehn JH. Erratum to: Calnexin, an ER stress-induced protein, is a prognostic marker and potential therapeutic target in colorectal cancer. Translational Medicine. 2016;14(1):222
http://epubs.rcsi.ie/physiolart/113
Physics Commons, Physiology Commons


Flickr have massively changed their website recently, and I took the chance to go through all my old photos and re-organise them a bit, so I'll be digging up various things from the archives over the next few weeks. Here's some of Bracknell from 2005.
It was built in the post-war period to house all the people leaving London. At the time a lot of people wanted to leave the city and have their own house with a garden. My family included, that's why most of them are still in London, but I grew up in N Kent. I've often passed through Bracknell by car, I went to university in Reading, very nearby, and some family friends live a couple of miles away too. Driving through Bracknell would often make my dad yell things at buildings through the window. My dad's a (retired) surveyor, and he gets very het up about bad town planning and dodgy gutters.
I have never had a nice time in Bracknell. In 2005, I was working in a camera shop in Reading, and they used to send me to cover at Bracknell sometimes. Their branch was tiny, and the manager was very unpleasant to work with. I had the choice of eating my lunch in the stock cupboard under her critical eye, or go for a wander around the desolate 60s town centre. I went for the wander every time. I got a massive sack of expired slide film from work, and I could develop it for free anyway, since I worked in the lab, so I tried out every brand of slide film, to see which I liked most for x-pro. This Fuji Astia was my favourite, but it seems very hard to get hold of. All the photos are taken on an Olympus XA2- an ideal camera when you don't want to lug an SLR around with you- and on Astia x-pro'd in C41.
In 2005, a lot of the buildings were empty, and there was a strong smell of urine on concrete around. Apparently things have improved a little, and there are grand plans to rennovate the place, but I have no reason to go there. The last time I was there, in 2008, I dislocated my shoulder playing bowling. I didn't know this was something that can happen, but there you go. Bowling is more dangerous than you thought.


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Home / FEATURED / Takeaways: Week 4 — Look back, look ahead
Takeaways: Week 4 — Look back, look ahead
By Chad Barnett
Piedmont-Glencoe: Been a Long Time
It has been nine years since Glencoe has beaten Piedmont and most of the games haven't been close; in the six games they've played in that stretch, only one — 13-12 in 2010 — has been so. The last two years, the Piedmont Bulldogs have won 41-7, only slightly closer than the previous year's 49-7.
Despite the teams' respective rankings — Piedmont No. 3, Glencoe No. 5 — expect the Bulldogs to maintain control following this Friday night's clash in Glencoe.
The Yellow Jackets do have some talent. They have four returning all-state players and already have dispatched one ranked team this season (Wellborn). They have a good head coach in Lee Ozmint who teaches fundamentals and a whole lot about toughness. But Piedmont has an advantage on the perimeter I would expect to be exploited.
Wellborn, a team known for its Notre Dame box style offense rather than their passing game, took advantage of the Glencoe secondary and built a strong lead. Piedmont has those same type skill players, if not more.
Alexandria: Oh, to be young again
KEENAN WOODRUFF
It may have lost the game, but Alexandria came away from its loss to Lincoln with a huge bright spot for the future.
While the Valley Cubs already knew about their talented freshman running back, Keenan Woodruff blasted onto the scene with a 220-yard, two-touchdown performance against the Golden Bears. He scored on a 57-yard run the second half and a 46-yarder in the first that will turn out as one of the best runs of the entire 2014 season.
He's a little undersized but that's to be expected with a freshman.
Lincoln's head coach Brad Wallace already knew of Woodruff, too, stating after the game that the coaching staff was concerned how to limit his playmaking. In the end, the Bears did enough to win the game, but for a little while it looked as though a freshman was going to take down the Bears in the Valley.
Wellborn: The first of many
Wellborn picked up its first win last Friday in dominating fashion. The Panthers thrashed a Pleasant Valley team that came into town riding a high after a win over Weaver, but the Raiders' momentum was quickly taken down a notch by a 30-7 halftime deficit.
Wellborn started out the year with an understood disadvantage. It entered the year with contests against two state ranked opponents — Saks and Glencoe – so don't let that 1-2 start fool you. The Panthers will still make a run this year.
One of their biggest bright spots is coming from an unlikely source. Senior skill player Corey Tignor barely knew how to put his cleats on two years ago. Today, he's a dynamic playmaker. While he had only two catches for 32 yards last Friday he delivered some major blows on defense.
"He's worked real hard to get where he is today," Wellborn head coach Jeff Smith said.
Saks: Smith-to-Harris an easy transition
One of the few concerns for Saks in 2014 was replacing quarterback Tre Smith. After all, he led the team to their best run in decades and went on to play FCS college football. Replacing that production would be no small task. Enter Devin Harris.
Harris, a running back last fall, has been tremendous for the Wildcats. Last week, he continued his assualt on opposing defenses with a 205-yard, five-touchdown performance in a 38-16 defeat of Cherokee County. He had a 170-yard performance in his debut under center against Wellborn.
Chad Barnett covers high school football for the "Pigskin Roundup." Read his impressions of the high school football week that was every week at East Alabama Sports Today.
← Previous Story Poll teams on collision course
Next Story → Piedmont's one focus (and it's not on No. 1 — yet)