Arrhythmias in the pediatric population are frequent. Patients who have been diagnosed with arrhythmias may frequently be depressed or have anxiety due to many factors such as exercise limitation and worries about the future. Usage of cardiac devices such as pacemaker (PM) and implantable cardioverter defibrillators (ICD) have a negative effect on patients' quality of life and psychiatric health. In our study we aim to investigate this effect along with the affect of resilience. To evaluate quality of life, Pediatric Quality of Life Questionnaire (PedsQoL), to evaluate psychiatric wellness in 5 areas (anxiety, depression, somatization, anger and negative sense of self) Brief Symptom Inventory (BSI) and to evaluate resilience Connor- Davidson Resilience Scale (CD-RISC) were used. A total of 71 patients and 62 healthy controls age between 2-18 were enrolled. In the patient group mean physical health summary score, mean psychosocial health summary score, mean total scale score, mean emotional functioning score and mean school functioning score were significantly lower than the healthy group. There was no relation between quality of life, psychiatric pathologies and resilience versus gender, type of device, implantation method and age, education, physical activity and patients age. Patients using an ICD had a significantly higher anxiety level than patients with PM. Also ICD bearing patients who received shock in the last year had a significantly higher level of somatization. In conclusion having a intracardiac rhythm device has a negative effect on patients psychiatric health and quality of life. Doctors should be aware of this and take swift actions towards eliminating them.


Turkish President Erdoğan's three-day visit to Berlin and Cologne ended on the weekend. Despite harsh criticism from the German president and chancellor, Erdoğan concluded that the visit had been successful. It did not amount to a fresh start in relations between the two nations, some commentators say. Others call for the dialogue to continue.
Why not talk about equality?


text:
Kandara, Anguilla
Bedrooms 6 (12 guests permitted) 8 (16 guests permitted)
Kandara
West End Bay, Anguilla
Villa Kandara, West End, Anguilla.
Villa Kandara offers travelers to the western end of the island of Anguilla a truly opulent spot to enjoy a holiday. With more than ten thousand square feet to savor, it is a modern masterpiece of architecture and design and offers an array of indoor and outdoor living spaces that are sure to delight all who visit.
One look at the eight-bedroom villa shows that it was designed to place an emphasis on the superior setting. Tucked just above the water, it is a lovely, estate-like property that features an enormous garden and lawn that frames the infinity-edge pool and fully-furnished terrace. The lawn is also home to a sunken lounge sitting right at the water's edge. Back at the pool, there is the main body of the swimming area and two plunge pools alongside the gazebo. This is another elegant lounge that offers wonderful sunset and sea views.
The terrace backs up to the verandah that features lounging and al fresco dining areas, and among the other outdoor living spaces is the truly inspired rooftop lounge that is sure to delight all who pay a visit. Stepping inside of the villa, there is little difference between indoor and outdoor spaces. The large living room area is furnished with posh sofas and chairs, an entertainment system, and opens to the terrace. The enormous dining room is nearby, and it uses the same natural materials and low-key palette as the rest of the space.
The bedrooms are divided between upper and lower levels, and each has a terrace or balcony. There are three king suites with large and luxurious private baths, one queen suite and two dual queen suites with baths. All have entertainment systems and use the same appealing décor as the rest of the villa. On a separate Guest House, you will find two additional king-size bedrooms, both en-suite with a living area in between.
With its large and private beach cove to enjoy, its expansive grounds, and its remarkable interiors, the Villa Kandara is that rare find that travelers of all kinds will love and year to revisit almost as soon as they have departed. Ideal for larger groups or families, it might also be the ultimate spot for an intimate destination event.
Lot Size: 1 acre Interior Area Size: 10000 ft²
Bedroom 1: Bedroom with a king-size bed, A/C, ceiling fans, TV, access to terrace and en-suite bathroom with bathtub, vanity and wc. 2 guests maximum
Bedroom 4: Bedroom with a queen-size bed, A/C, ceiling fans, TV, access to terrace and en-suite bathroom with bathtub, vanity and wc. 2 guests maximum
Bedroom 5: Bedroom with two queen-size beds, A/C, ceiling fans, TV, access to terrace and en-suite bathroom with bathtub, vanity and wc. 2 guests maximum
Bedroom 7: Bedroom with a king-size bed, A/C, shared living area and kitchen with Bedroom 8 and en-suite bathroom with shower, vanity and wc. 2 guests maximum
Basketball Hoop
Coffee Maker (Espresso/Nespresso)
Covid-19 Certified
Daily Turndown Service
View - Sunset
VOIP Phone
Check In / Check Out: 3pm / 11am
Damage Deposit: $1,000.00
One roundtrip airport transfer included
2022 Jan 8 to Apr 22 January 8, 2022 - April 22, 2022 (7 night minimum) 6 8 $5,250.00 $5,950.00 $36,750.00 $41,650.00
2022 Apr 22 to Nov 19 April 22, 2022 - November 19, 2022 (7 night minimum) 6 8 $3,750.00 $4,450.00 $26,250.00 $31,150.00
2022 Nov 19 to Dec 17 November 19, 2022 - December 17, 2022 (7 night minimum) 6 8 $5,250.00 $5,950.00 $36,750.00 $41,650.00
2022 Jan 8 to Apr 22 January 8, 2022 - April 22, 2022 (7 night minimum)
2022 Apr 22 to Nov 19 April 22, 2022 - November 19, 2022 (7 night minimum)
2022 Nov 19 to Dec 17 November 19, 2022 - December 17, 2022 (7 night minimum)
Kishti East
(2)
Meads Bay
1.5 Shared
Kishti East Anguilla
Triton - Kamique
LockRum Bay
Triton - Kamique Anguilla

redpajama_set_name: RedPajamaCommonCrawl


text:
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The Palm Beach Post
The Palm Beach Post Homepage
Obituaries Section
Anne Heyman
Horse rider killed in Wellington accident identified as New York lawyer Anne Heyman
Published by The Palm Beach Post from Feb. 1 to Feb. 28, 2014.
How do you know Anne Heyman? (Optional)
We loved Anne, her friendship...and all her accomplishments....do believe she went after and did all she could for and with so many in her life..(being born on Mother's Day was perfect for Anne's start in St. Augustine )
Anne loved every minute of every day....people and writing about them made Anne's life complete....Weren't we lucky to have seen her in action? Alice and Don Tossi
Alice tossi
Rip Lady Anne; you are much admired for the incredible work you did. So sorry for the loss to your family and the community.
Sonya Atkins
Anney Heyman R.I.P a special condorance to your familly,your parents to all those who knew you not only Americans but the Whole World.I never knew you but when I visited Agahozo Sharom in Rwanda and hard about what you had done I fill tears coming down.The Love you had was a real gift from God I mean he put the Love he had in your heart.No one can do this unless inspired by God.Truly speaking it is a loss to the World to miss you but still God wanted to take you to Heaven to keep you for himself sorry to say no one can do such things and stay long take an example of Jesus he lived only 33 years and many more.Anney R.I.P R.IP
Rudasingwa Jean Bosco
Dear Seth and family; I was very saddened to hear of Anne's untimely death. She had so much to offer to the world. I worked with your family and her charitable organization while at Anchin. It was a pleasure knowing all of you. I had to retire in 2011 after my stroke. My deepest sympathy to all of you. Sonja Lepkowski
Sonja Lepkowski
As a former employee of ASYV, I admired Anne Heyman for having this wonderful vision and living her dream with such love for these kids. God bless her and my deepest sympathy extends to her family. Best to you all--Dali Evans
Sandra Drumm
Anne . Your wings were on you. As you left to go to heaven. With your pretty smile. I worked at equestrian. Say hi to heaven.
I'm so sorry to hear of your accident. RIP
Lillian Heller
I am both envious and exhausted reading of your accomplishments . You have done the work of 5 careers in the short time you were here .
I give you my heart and thoughts of those left behind in your care. I would gladly pick up the baton if I only knew how. The good people of Earth have lost a true comrade.
Pat McGowan / Seattle
Pat Mcgowan
As lucky as heaven is to have you, those of us still here on earth are truly missing out.
Rebecca Barkai
Anne, you were a gift sent from God to touch and bless our lives. You truly knew the meaning of life and loving your neighbors as yourself. I was always mesmerized by your love towards us, your courage, your passions and like you always said "The Sky was the limit". Truly, you were a Unique person. I will never forget you, thanks for founding Agahozo-Shalom and for giving your all and all to the communities. Your reward in Heaven is greater. Rest in Peace. Love you.
Sonia Mikanagu
I was fortunate to interview Anne in 2001, when she was honored at the DOROT gala for her compassion and dedication to the elderly, the same distinct qualities that led her to successfully found and lead the Agahozo Shalom Youth Village in Rwanda, half a world away from NYC. She was truly a citizen of the world. I deeply admire her philanthropy, which had not a trace of ego in it. I admire how her desire to help others came from a very Jewish perspective, and I am in awe of her focus, intelligence, drive, will and tenacity--the same qualities that underlined her success as a public prosecutor in the Manhattan District Attorney's office were behind her success in founding a village for orphaned victims of the Rwandan genocide in a country she knew little about, until her passion for good works led her there. Many people express compassion for those less fortunate than they are, but few people act on that compassion, and fewer still are as successful as Anne was in making their good deeds a reflection of their compassionate words. She was smart, savvy, determined, with an unstoppable will, a great love, and concern to make the world a better place than she found it. I feel so sad that she is gone way too young, but she died doing what she loved to do. She had a great passion for riding horses and a great love for animals as well as people. I remember years ago when she broke her back in a fall from a horse. She was in a back brace for months, and after it came off, she went right back to riding and competing. She was unstoppable, and I believe that she will continue to live on in her good deeds, in the Agahozo Shalom Youth Village that she founded, and in the hearts and minds of the many people all over the world whose lives she touched and who will continue to draw inspiration from her example. My heart goes out to her husband, Seth, and to her children--Jason, Jenna, and Jonathan--who lost their mother way too young in their young lives--as well as to her parents, siblings, in-laws, and many relatives. She was indeed a rare and shining example of what humanity can aspire to at its best. I am in awe of her, and I will continue to draw inspiration from her all the days of my life.
Anne Whitehouse
Rest in peace Anne.You led an exemplary life and were a true inspiration to anyone fortunate enough to have known you. Heartfelt condolences to your family.
Debbie Rosenblatt
tsofnat cohen
I met Anne and Seth almost 20 years ago. I was traveling after the army service and Anne was looking for a Hebrew speaking babysitter for the kids. We spent a year together. During this year i had an amazing opportunity to be a part of the Merrin family. Anne, a generouse, honest, loving person. the only things she cared about is the family, children and Seth and always looked around for the people in need, supporting and actively involved in numerous projects, very small and very big to make this world a better place. I learned from Anne how to love a child, how to take care of your beloved ones, and what is important in life. Anney I miss your voice on the phone: "Hey Tsof, we are in Israel", I miss your tears when talking about all your sons- Jenna, Jase and Yoni and all the thousands all over the world. Something from us died with you. Something from you will live with us. Love from my crying heart. Tsofi
Dear Anne,
Thank you for touching my life and showing me the real meaning of humanity. I saw tangible love in you; your smile, your hugs, your humility and your determination. You will always be my all time role model as a wife, a mother and simply a universe citizen. Thank you for your great work to my country, you were a God sent angel. Your legacy will guide our actions in every way to make you forever live in this beautiful village.
You are now our Ambassador from Heaven, please tell God, to give us more time to emulate you… Love and miss you Anne!
Dimitrie Sissi
they say you never know what you had till it gone, but the truth is we knew exactly whom we had and we thought we could never lose her till it came, we cried a river, but we are luck to know you, to live and to be loved by an important mother, she was special to me, her kindness, humanity, wisdom, legacy, and beautiful smile stay in my mind, you came as our shelter, mother and an angel sent by God. we will always keep your memory, not only that you dead but also you lived. even a dictionary can not define you, even a poetry can not praise you, even a known writer can not write each good attitude and your uniqueness, even a solder can not compete in your war, even a loyal can not judge what you've done, even a president can not get a better speech on your life. only God knows why. you left early.
I love you mom ANNE HEYMAN.
Ishimwe Ngarambe Celestine
The pain is severe-the hurt real.The world lost a "Rock Star".We lost a wife-a mother-a daughter -a sister-a cousin -a niece and our darling Anne Elaine.We love and miss you.I will try and take care of them all.
ann Katz
WHAT A WONDERFUL HUMAN BEING LEAVES THE WORLD, ONE ASK WHY SO SOON. all my love to his family.
my thoughts and prayers are with you and your family..Ray Tierney
My mother was one of the most amazing, driven, brilliant, fun-loving, generous, kind, and inspirational people I have ever heard of.
I was so lucky to have known her, to have been related to her, to love her, and to have been loved by her.
My mom was one of my best friends and closest confidants. We didn't keep many secrets and we never lied to each other. She was not only an amazing person but an amazing mother. She was always there for me, from flying to meet me in/pick me up and take me home from Israel when I had mono to going to Colorado for a day to watch TKD nationals, or just taking me out to lunch when she had a rare moment of free time, she was always there.
My mom died doing what she loved. She often described riding horses as something she couldn't live without. After breaking her back, neck, wrist, ankle, and a million other parts, and 4 or so concussions, she got right back up on that horse. Some might call that stupid or stubborn, but it shows a lot about how she lived her life. My mother was brave, strong, tenacious, passionate, and never listened to anyone who told her she couldn't do what she wanted to do.
I live every day of my life to make her proud and I will always continue to do so. I love you, Ims
Jenna Merrin
Anne Heyman used her intellect, her resources and her heart to leave this world a better place than she found it. She exemplified tikkun olam and will continue to live in her good works.
I did not have the privilege of knowing Ms. Heyman, but I mourn her loss. My heartfelt condolences to Ms. Heyman's friends, family and colleagues.
Leanne Tobias
In memory of Anne Heyman.
Helen Guy
Dear Hermia and Syd, I learned of Anne's death this morning reading the NYT. Although I never met Anne, I knew of her marriage, her children, her life, her accomplishments and your immense pride in being a part of her life as she matured into the philanthropist she became, from my many visits to your home in Villanova and Gwynnedd over the last 20 years. You showed me your photos and told stories about her life. I feel so sad for you at the loss of such an immensely talented person, and especially your loss of your beloved child. I send my condolences also to Daniel, Lauren and Jason, and Anne's husband and children and extended family.
So incredibly sad and tragic. The world was blessed by her presence and warmth. Anne and Seth changed many lives for the better with their generosity and big hearts. Anne's leadership talent and her vision was inspiring and so terribly needed. Sending comfort and prayers to her family.
Denny Reed
i am so sorry for your loss! may God bless her and her family! i hope you will find comfort that she passed doing what she Loved!?,...
laura doan
It was my privilege to know Anne. My deepest sympathy to her family.
Penny Kinnally
My deepest sympathies and condolences to Seth, Jason, Jenna, and Joni, a truly wonderful family. I learned of this terrible tradgedy and felt compelled to touch base with a wonderful group of young people that I shared ideas about math many years ago.
Mel Klenetsky
As your descendants from Agahozo, we are very sad but thanking God that we have got chance to know. you have made us who we are and ready to strive for what you have been wishing us to achieve. For sure you will be happier to see us shining as it was your wish towards us.
greater of all May peace and comfort find your family during this difficult time.
Kagame Jean
We will light a candle of hope, love and gratefulness of Anne. As OT's and horsewomen we are saddened by this loss...may you be surrounded in love and light at this time of darkness....
Our Rabbi and executive director of The JCC in Manhattan, Joy Levitt, came directly from Anne's funeral on Monday, 2/3 to a JCC all staff meeting. She abandoned what she was going to talk about and instead talked about Anne. She told us how Anne changed the world by starting the orphanage in Rwanda. She reflected on how many people must have told Anne that this was a crazy idea, that it couldn't be done. But, she said, Anne was unstoppable. She didn't listen to the naysayers. Joy inspired us to think about ways that she could support us and our ideas so that we too could change the world. I was incredibly moved by the story of Anne. I am sorry that I didn't get to meet her in person but I want her family to know that she has inspired all of us at the JCC to reflect on how we can make a difference. May Anne rest in peace. And may she look down on all of us and be proud that we are in fact carrying on her legacy in the good work that her example has inspired. May her family and friends and the children and people of Rwanda be comforted by the memories of how she lived and cared and believed. God bless.
Caroline Kohles
What a sad but amazingly uplifting service each of you put together to celebrate your mother, your sister, your wife and your friend. While I had always known Anne Heyman to be a force of nature in the context of the Merrin family, Liquidnet and ASYV, it wasn't until yesterday that I learned of the impact she had made on a global scale. She had been saving people her whole life, starting with her brother and ending with the world. How lucky I am to have personally known her. How lucky we all were. I wanted to include this picture of Anne because if you look closely at her feet you can see she is on her tip toes with excitement. It's how I imagine she lived her life and it makes me want to do the same. Rest peacefully Anne.
Katy Hansen
Seth, I am so sorry to hear this terrible news about Anne. My thoughts are with you and your family during this terribly sad time. Emilie Bakal
Dear Seth, Jason, Jenna and Yoni,
Living in the desert we learn to appreciate every flower we meet along the way. Having been touched, when we celebrate Anne's life it will be with kindness, generosity and love.
Marcel, Ronit, Avishag and Michael Debowy. Kibbutz Ketura
Heartfelt condolences, Seth, to you, your children and your wife's family. May the memories of good times help you through this difficult time.
Cindy Lackow-Gavelek
My sincere condolences to the Merrin and Heyman families on this tragic loss. You are all in our thoughts and prayers.
-Nick & Freda Savona
Nick Savona
No words can express the deep sadness we feel for Seth, Jason, Jenna, Yoni and the extended Merrin and Heyman Family. May Anne's memory be for a blessing always and give you the strength to go forward. Heartfelt sympathy and condolences to the Merrin-Heyman family.
With love from Michele, Maya and Adam Billig.
This is a loss to humanity and all the causes she so tirelessly empowered. Let her life be an inspiration to us all to do better and have meaningful existences incorporating her values. Sincere condolences to the Heyman and Merrin Families. A unique human being has left us but the memories of her actions will live on.
Lori & Gary Castle
I am devastated by this tragic news. My heartfelt sympathies go out to the Merrin and Heyman families on the loss of this beautiful, unique, energetic and generous woman. Dr. Lynn Burkes
My deepest condolences Seth and his family. This is tragic loss of a wonderful life, person, hero, mother, wife and savior for hundreds of orphans.
Rest is Peace Anne.
Chris Iacovides
I still can't believe you left us.Anne,I can not find something to say just not because i do not have words but i can say that I WILL MAKE YOU PROUD.I love you.and I WILL MISS YOU.
Pascaline NIYIGENA
I am so sad to hear of Anne's passing. My heart goes out to you, Seth, Jenna, Jason, and Jonathan. Anne was a gentle, intelligent, and good person and I am honored to have known her. I will miss her.
Karen Brodman, MD
Dear Seth and family, I was deeply saddened to learn of Anne`s untimely passing. It is such a tragic loss to your beloved family,dear friends and to the community which she unselfishly gave so much support. Although, I know that this is such a difficult and sad time please, take comfort and solace in the knowledge that she has truly made a vast difference in the lives of so many people whom will be forever grateful. Her extradordinary passion,inspiration and commitment certainly has made the world a better place. I feel so blessed to have known Anne and your wonderful family. My thoughts,prayers and sincerest condolences are with you all. God Bless! Barbara Nestler
What does one say? Any loss is immeasurable. Our lives forever change when we lose such a beautiful being. May the sorrow you feel in your heart lighten by the love that surrounds you. Peace and love - Juliet Stams and Family
We must embrace pain and burn it as fuel for our journey. ~Kenji Miyazawa
Juliet Stams
To work with Anne and Agahozo-Shalom was an inspirational experience, I learnt so much from her and also her stories. I will do my best to aspire to do more in my philanthropic work and continue her legacy and so much she taught me. I have fond memories and a diary of family night stories from the village.
Samantha Taylor
Although I never had the pleasure of meeting Anne Heyman.. She sounds like an amazing, caring, loving woman!! I'm sitting here reading about her death and watching the videos from the graduating class of 2013. My heart breaks from all the kind words.. And the babies that now feel like they have no one!! God took an angel.. But one that continues to live on in so many lives.. God bless you all!!!
Latanya Edwards
Our sincere condolences to Anne's family. We heard Anne speak years ago and her contagious enthusiasm and passion for the Rwandan children was an inspiration to us. It was impossible not to get involved with Agahozo Shalom after meeting her!
Be so proud of the inspiring and incredible woman, who helped change the lives of so many unfortunate Rwandan youth.
Jill Levine
Dear Seth and family,
the world grieves with you for the loss of anne - a beautiful , brilliant and unstoppable force of nature. We have never met anyone like her and we are all better for having had her in our lives. An inspiration to so many, who led by example and never EVER took no for an answer. we send our love and deepest heartfelt condolences to you , your kids and your parents. Anne's legacy will live on forever. Nancy and mark gilbert
What a wonderful, amazing woman Anne was, someone who truly made the world a better place. She was kind, funny, witty, and a good horsewoman in addition to everything else that has been said about her as a person and as a philanthropist.
Linda Broussard
What an inspiration. What a hero.. What a loss. I did not know Anne. But what I've read and heard about her is absolutely remarkable.. May her neshama have an Aliya
Chana G
To the Merrin and Heyman families, Anne was an amazing woman who will never be forgotten, by family, friends and all the children whose lives she touched. May you all find comfort in each other and the love she had for all of you.
suzanne jacobs and jeffrey borkan
suzanne jacobs
Dearest Seth, Jason, Jenna and Jonathan,
My heart is breaking for all of you now. Although I have not seen you all in close to 20 years, I have always thought of you since my teaching days at Heschel. I was Jason's teacher in Pre-K as well as Jenna's. They were both some of my favorite students, such loving, creative children, exuberant, full of life and funny...just like their Mom, Anne. Jonathan was only 2 or 3 at the time I taught there. Anne was an incredible person. She was so involved in Heschel and her family. I always admired her tenacity and caring nature. I especially felt close to her and a few other parents. I only now discovered so many things that she accomplished, what a truly remarkable individual. The world was such a better place having her in it and she will live on in our hearts and memories for a very long time to come. May you all find solace and comfort during this tragic time. May Anne rest in peace and may her soul make an aliyah. Forever in my thoughts!!!
Rebecca Barkai (Speiser)
Anne Heyman is a hero. The whole world is glad to have had such an incredible person..
There is a growing number of smiling faces in Rwanda because of her unequaled actions in bettering Rwandan future.
Your big American, Rwandan, israel families miss you so much.
Patrick Munyurangabo
Our deepest sympathy go out to the Merrin Family. Your friends Carline Trans. Erick & Laurie Rodriguez
Erick Rodriguez
The candle you lit for many hearts will never burn. I still cant believe you are gone...you will be dearly missed. Our heart felt condolences to Seth, Jenna, Jonathan, Jason and to the entire extended family. Jaden, Denise and JC Nkulikiyimfura.
Denise Umunyana
After hearing so much about Anne,I finally met her a few weeks ago on January 19 at the Agahozo graduation ceremony in Kigali.An amazing woman with a beautiful spirit. I feel very priviledged to have met her. My heart goes to her family and the Rwandan orphans whose lives she has transformed.She will be greatly missed but always remembered. RIP Anne Heyman.
Jacquie Mukete
May the God of comfort be with you in this time of grief. May all fond memories of Anne stay close to your hearts. Psalms 46:1
Sincerely, A.O.
Anne was an extraoridnary person. One who was able to see injustice and act upon it, impacting the lives of many in a remarkable way. Her legacy will live on. Condolences to her immediate and extended family for this horrible tragedy.
Anne was an embodiment of all virtues.She showed humility, love and compassion and above all selfless.Politically she would be a heroin ,Religiously she would be a saint.May her soul rest in peace.
Bonaventure Mujyeneza
Anne was an embodiment of all virtues.She showed humility, love and compassion and above all selfless.Politically she would is heroin ,Religiously she would be a saint.May her soul rest in peace.
Dearest Seth, Jenna, Jason and Jonathan,
My heart is filled with grief for the untimely and tragic passing of Anne. Visionary, humanitarian, imaginative in the deepest fiber of her being – a pioneer as she strove to repair the world. Her work touched the lives of thousands. She was a bright star, illuminating everything she touched. But whatever she was doing, whenever we spoke, first and foremost she shared her pride and love for each of you. I will always treasure her friendship and her unswerving partnership in building a better world for the elderly at DOROT.
Jerry joins me in expressing our deepest condolences to you and the entire Merrin and Heyman families.
Vivian Ehrlich
I'm so very very sad to hear this tragic news. I knew Anne from my riding days at Overpeck. Often she gave me a lift back to the city. She was kind, funny, smart, and beautiful. I ran into her a few years later at the NJ Horse Show. I've thought of her from time to time and was sorry to have fallen out of touch. I'm thinking of her family at this time and my thoughts are with them at this time.
Lisa Shapiro
Scott, Kim, Natasha, Tara, and Olivia Snapper share the pain and grief with the Heyman/Merrin families. Anne's mission to make the world a better place through all of her activities runs deep in and should inspire all of us.
I met Anne last year to learn about her work in Rwanda. She was a remarkable woman. I am so sorry for her loss. She has changed the lives of so many.
I met Anne several years ago when she was in Boston raising money for her Rwanda project which is so awesome. My wife is an equestrian and we shared that. Anne was a beautiful human being, dedicated to making the world a better place. My sincere condolences to her family. So sad, so brimming with life.
Steve Fischman
I'm very sad to hear of the loss of such a phenomenol woman. May her spirit and works carry on with her watchful eye from above.
Dear Seth, Jason, Jenna, and Yoni,
We are so very sad for your loss. Anne performed acts of ??? ????? over and over. She was a true woman of valor. We cannot possibly imagine your pain, but we hope that all of the great memories you have will comfort you now and forever. ??? ???. Lori, Ted, Maddie, and Marlana Fireman.
Lori, Ted, Maddie, and Marlana Fireman
My husband and I met Anne for an amazing evening in CT. Her passion and determination were infectious. In just a couple of hours she made a huge impact on everyone in the room. The tragic circumstances of her untimely passing are almost incomprehensible. But her spirit and good works will undoubtedly have an everlasting effect in all she touched. Our sincerest condolences to all she loved and to all those who loved her.
Carole and Burton Orland
We were saddened to learn of Anne's untimely passing. She truly was an exceptional person.We are sure the pleasant memories of her will be a source of comfort to you now and in the future.
With heartfelt sympathy.
Joy and Nat Feldman
Joy & Nat Feldman
It is with such sadness that I sign this book. Anne had such a huge impact on so many lives including mine. I had the pleasure of working with Anne and her horses when she first started riding at Overpeck years ago.She was always so supportive and had such empathy for her horses. My heart goes out to her 3 beautiful children and her wonderful husband Seth. The world is a better place because of you Anne. Godspeed.
Michelle Grayson
Well done, good and faithful servant. You leave behind a hole in the hearts of those who love you, but that hole is filled with love and memories . . . Your job on Earth was done, but your job in Heaven has just started. May the comfort with which you comforted so many be the same comfort that now holds the hearts of those who miss your presence here on Earth.
Holly DeVos
I am so sorry for your loss. Anne was a fearless woman with a huge and wonderful heart. I heard of her death and felt a great loss and sorrow. May her memory bring you love and strength. My heart goes out to you, Seth and the kids. Love and prayers, Beth Cohen-Preiss
Beth Cohen-Preiss
Our deepest, heartfelt condolences to family, friends, and all connections. An amazing woman and horse person, gone too soon. May she rest forever in eternal peace.
KarenandPavel Blaho
Our thoughts and prayers are with your family at this very painful time. She was quite extraordinary and so many are grateful for the gift of her life. May her memory be for a blessing and hope you can take some comfort in your cherished memories.
The Tobar and Neustadt Families
You will be missed by your family and your adopted family. You were truly an inspiration to everyone who knew you. Our thoughts and prayers are with Seth and the kids.
Rachel and Mark Lipschutz
RIP DEAR ANGEL!
Thank You For Your Compassion To Others.
Bob Howe
Our sincere and deepest sympathy to Anne's family. Our thoughts are with you all.
Helen Juhasz
Dear Seth and family, I just learned of this tragic news... we are, in Boston, all overwhelmed. Anne's memory and her work are and always will be an interminable blessing.. for all she did and for all those who she touched in her living years. She will always be in our hearts as we, at Tufts, are with you and everyone in the family at this difficult time.
l'shalom,
Ira M. Herman
Professor of Developmental, Molecular and Chemical Biology and Director, Center for Innovations in Wound Healing, Tufts University, Boston MA
Great loss to mankind! Anne made a huge impact in so many people's lives in her own quiet, modest way.
Judy Spiegel
Glori
You will be missed ...you were an inspiration to all ...you will be remembered for your loving spirit
Deborah Baum (Brooklyn NY)
I knew Anne from when she rode with David Kenner Boley and Penny Kinnally at Overpeck. She was always a genuine individual and was so proud to ride with her horses. They were a part of her and she never took that concept lightly. It was quite refreshing to watch because her horses knew when "mom" was on their back. It's a special connection between horse and rider and Anne always had that with her mounts. She never forgot that it took a village to make a winning team including the trainers, grooms, and fellow boarders who all supported each other. She will be missed greatly but her legacy will continue in all the wonderful work in Rwanda. My sincere condolences to all!
Stephanie Henkin
Anne was good and did so much good to many young people in my country. To Seth, your children, extended family and friends: we are grieving for and with you. We wish you strength and serenity! I have no doubt Anne is peacefully resting. Her energy and spirit lives on in the land of a thousand hills! Louise Mushikiwabo, Foreign Minister, Rwanda
Louise Mushikiwabo
Blessing to the family.
We are deeply saddened by the loss of Anne she will be missed. Our prayers are with the Merrin Family and everyone who's hearts Anne touched.
John Redfearn
So sorry for your loss . rest in peace Anne . your legacy will live on .
wendy ellis
It was a pleasure to spend a week at the Village and make a small difference in the kid's lives and hopefully continue Anne's message.
Chad Cumberworth
Anne - a great attorney & humanitarian
Kathleen Williams
All of us at Big Dog Ranch Rescue are celebrating Anne's LIFE and her legacy of living, loving and giving will live on as we follow her example and make our world a better place to live. Shalom
Big Dog Ranch Rescue
Our grand mum we will never forget your support in A.S.Y.V and RIP.
ko lo
YOU WILL BE MISSED. MY DEEPEST SYMPATHY TO THE FAMILY. YOU HAVE MY PRAYERS.
ETHEL KELLEY
May God bless you and your family in this time of sorrow.
It saddens me. I don't know Anne but she seems to be an extradonary person someone who should have stayed with us a lot longer! My prayers are with your family and friends.
My sincerest sympathy to Anne's family and extended family. A tragic loss to the horse industry also.
Jeannine Chambers
RIP Anne.
Bonnie Snow
My friend and former student Anne was one of the rare and truly blessed individuals whose personal light touched everyone she met. Anne, and her extraordinary family, will continue to make the world a better place for us all through the practice of their faith and grace. Anne's legacy is one of meticulous care, boundless energy, absolute righteousness,and most importantly...infinite love!
David Kenner Boley
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Funeral Director Aly accepts lockdown hero award
A Lincolnshire Co-op colleague has accepted an award at the Lincolnshire Lockdown Heroes Awards 2020 in recognition of her unwavering dedication and exceptional efforts during lockdown.
Aly Gratrick, Funeral Director at Proctor's Road Funeral Home, was presented with the award at a socially distanced ceremony held at Lincoln College where she was recognised for her extraordinary work.
The awards, organised by The Lincolnite, Lincoln College Group and Lincolnshire Chamber of Commerce, received over 370 nominations, which were then narrowed down to eight thoroughly deserving winners.
Lincoln College Group CEO, Gary Headland said: "This was an opportunity to celebrate the wonderful examples of human compassion, resolve and bravery that we saw in Lincolnshire throughout the lockdown period.
"Our winners really stood out as extraordinary and we were delighted to be able to invite them onto our campus for a small socially distanced celebration today."
Aly was nominated by a colleague for working passionately and tirelessly for the families who lost loved ones throughout lockdown, even going as far as calling people after funerals to make sure they were okay.
Aly said: "The nomination was a complete and utter shock - I knew nothing about it! I feel honoured to have received this award and truly privileged to be able to do my job."
This isn't the first time Aly's hard work has been recognised, after she received the Lincolnshire Co-op Silver Colleague of the Year Award in 2019.
Well done, Aly - what an inspiring achievement!


JVB Design House is a luxury-focused firm of Planners and Designers specializing in magnificent Destination Weddings & Events across the globe. Turning ethereal visions into spectacular realities, we believe destination celebrations are an art form. We don't simply plan and design them, we curate unforgettable experiences.
At the helm of it all is acclaimed A-List Destination Wedding Planner, Designer, and Author of Caribbean Wedding Style, JoAnne Brown. The design house works intimately with clients to craft an incredible occasion. Beginning with a request for proposal, our Planners will contact you to learn more about your needs and vision. Once qualified, we will work with you to put together a full plan, timeline and design. Most importantly, if your destination of choice has not yet been found, we will work with you to narrow down your dream destination. This will include a process of private site visits to the hand picked venues especially for you.
"JoAnne Brown is the Caribbean's most sought-after wedding creator, with the ability to beautifully bring every couple's wedding vision to life in some of the world's most extraordinary settings."


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Dil Ek Mandir () is a 1963 Indian Hindi-language romantic drama film directed by C. V. Sridhar and written by Raj Baldev Raj.

The film stars Rajendra Kumar, Meena Kumari, Raaj Kumar and Mehmood. The film's music is by Shankar Jaikishan. All the songs of this film were hits and were loved by everyone. The film was a major hit and ranked fifth on the box office collection list. The film is a remake of the Tamil film Nenjil Or Aalayam (1962), also directed by Sridhar.

Plot
Sita (Meena Kumari) is married to Ram (Raaj Kumar), who is diagnosed to have cancer. Ram is admitted to a hospital where he is to be treated by Dr. Dharmesh (Rajendra Kumar). Dr. Dharmesh is Sita's former love and both of them are very much uncomfortable to interact in front of Sita's husband. Sita suspects that Dr. Dharmesh will not be able to give her husband a fair treatment because of his love interest in her. When she mentions this to him he promises her that he will try his best to save her husband. Ram overhears this conversation and later suggests to Sita that she should marry Dr. Dharmesh after his death. Ram is to undergo a major surgery under Dr. Dharmesh, which will decide his fate. Dr. Dharmesh is seized with a feeling that he can't afford to fail in this surgery, as it might seem that he was biased due to Sita. He works hard for the preparation of the surgery, without proper food/sleep for a long time. Finally, at the end the surgery takes place. Dr. Dharmesh comes out from the operation theatre and tells Sita that the operation was successful and her husband is safe. He takes couple of steps forward and collapses. Long days of hard work for the preparation of surgery takes its toll, and he dies on the spot. The last scene shows Ram and Sita at the inauguration of a hospital built in Dr. Dharmesh's memory. Dr. Dharmesh's mother inaugurates his statue and everybody places flowers there.

Cast & Characters

Production
Dil Ek Mandir was directed by C. V. Sridhar and remade from his own Tamil film Nenjil Or Aalayam (1962). Meena Kumari learnt to play the sitar for her role. The entire film was completed in 27 days.

Soundtrack
The Music of the film was composed by Shankar–Jaikishan. Songs of this film are considered as classics. Singers like Mohammed Rafi, Lata Mangeshkar And Suman Kalyanpur crooned the songs in the album. Music was a hit after release with songs still remembered till date.

Awards
At the 11th Filmfare Awards, Raaj Kumar won the Best Supporting Actor Award and Arjun Dev Rashk won Best Dialogue. Kutty Padmini was recognised by Prime Minister Indira Gandhi at her residence along with Rajendra Kumar and Meena Kumari.

Reception
Sports and Pastime wrote "The subject of a love triangle and a doctor's supreme sacrifice in the pursuit of his ideals is not new on the Indian screen [..] but [..] director Sridhar presents this seemingly familiar plot with a zest and suspense that evoke praise".

References

External links

1963 films
1960s Hindi-language films
Films directed by C. V. Sridhar
Films scored by Shankar–Jaikishan
Hindi remakes of Tamil films
Indian romantic drama films

redpajama_set_name: RedPajamaWikipedia


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EASTERN IOWA REVIEW
Issue 8 - Spring 2019
All Things Anne - Issue 9
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Issue 5 - The SmartApocalypse
Contemporary Mystery
Debut Fiction
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MICHAEL ONOFREY
– man lives in desert – tree surgeon dumps cuttings off – man separates, sorts, cuts, and etc., and makes a business of it – woman (artist) shows up
– man is long-limbed – woman is slim and beautiful – no, woman is a little pudgy but still beautiful – woman sketches the man, who has veins trellising his forearms – does the man have tattoos – does the woman have tattoos - how old is the man – how old is the woman – why'd she come out there in the first place
Imagine: nothing but desert, call it the Mojave: pebbled, grayish, dull creosote colonies here and there, a mobile home (singlewide), graded dirt road leading to the singlewide – the dumping of trees and bush-cuttings takes place beyond the singlewide – the man has a backhoe for burying what he can't salvage: leaves, twigs, shrubbery – a shed with a couple of saws to make planks or 2x4s or slats or whatever – naturally sundried wood, not oven-dried, which some people want, lumberyards or carpenters, specialty carpenters who do work in the nearby metropolis: Southern California – there's also firewood that brings in money – the man knows types of wood, he has a book he employees if need be for identifying wood, the tree surgeon knows flora as well and answers the man's questions about wood or bushes or trees – the tree surgeon is bilingual, Spanish and English, it's free dumping for the tree surgeon, sometimes the tree surgeon has a crew of three or four men who speak Spanish and maybe English – the woman has viewed this: the dumping, the men, the comradery – let's call the woman Sally and the man Hoyt and the tree surgeon Manny – there is never any alcohol because both Hoyt and Manny are involved with AA, Manny more than Hoyt – Manny is married and has kids that he adores – Hoyt relates all this to Sally (i.e. Manny and his love of children) – Hoyt can't stand kids in any capacity, nor marriage for that matter – rattlesnakes, scorpions, tarantulas, coyotes and etc. OK, but no kids – Sally ventures out to Hoyt's residence in the desert for the sake of art and other activities
Hoyt owns nothing – the whole deal belongs to a wealthy realtor(s), husband-and-wife team who have a thriving office in the nearby metropolis and who have idle land and who support endeavors of an ecological-slash-environmental nature – solar panels are under consideration and so are Angora goats that would eat the foliage that's now getting buried – Angora goats produce mohair, desert heat not a problem, naturally colored mohair from goats with such fleeces (black, brown, rust-brown) a niche market, high-end – sometimes people from a university come out to have a look around, an environmental/ecological look around, they always call first, of course, their body-types are either gangly or obese
A coffee shop in a strip mall, Sally and her friend, Gale, are at a table next to a plate-glass window. They're doing lunch: iced tea, Greek salads, and a piece of fish, halibut maybe, cooked with olive oil and rosemary. Sally is saying: "Oh, Gale, it's sooo . . ." Gale: "Does he send you to the moon and back, Sally?" "Yes, but the thing is, I keep going and going and going, past the moon." Gale: "That bad, huh. Actually, that good. So what's next? Where do you and Hoyt go from here?" "I don't know. Hoyt says there doesn't have to be something next, except getting old and dying, or maybe dying before getting old." "He sounds very optimistic." Sally smiles, teeth well-maintained. "Can you build a future with this man?" "No, I don't think so." "So you're in it for the now, like in wow!" "I guess." "Well, that seems pretty good." "Yeah, but there are a few problems." "Oh?" "We have nothing to talk about, except the desert maybe. He doesn't have a TV, much less a computer and so forth. He reads books, used paperbacks that Manny drops off. Manny's the guy who dumps off the debris. And he has a pair of binoculars to look at birds and coyotes." "Who, Manny or Hoyt?" "Manny or Hoyt, what?" "Who has the binoculars?" "Hoyt of course." "Things could be worse," Gale says. "The only place he ever goes is to a gas station and a supermarket and a bank." "I see." "When he walks he's bent forward. Sometimes I think there's something wrong with him, the way he can sit and sit and sit and do nothing but look at the desert. I sketch him when he does that, but still . . . he doesn't move. He's like a reptile." "Really?" "He's very strong, in all physical aspects. But he's weak in mental aspects. He's got a cat, a calico, a female, spayed. But he hasn't named the cat. He calls the cat, cat." "Are you going to eat those olives, Sally?" "No, we have tons of olives at Hoyt's place. Here, you can have them." Sally holds her plate forth. Gale spoons olives off of Sally's plate.
"I can't take it anymore, Hoyt. I'm not coming back."
Hoyt stands, looking at Sally, end of October, weather marvelous. Sally's just gotten out of the cab of her pickup truck, a Dodge Ram. The driver's door remains open. Hoyt has come around from in back of his singlewide where he had been loitering on the patio. It's a windless day. The cat has followed Hoyt. The cat sits its haunches and looks up at Sally. Hoyt blinks his eyes, irises gray. A two-day growth of stubble is on Hoyt's oblong face, a billed cap atop his head. The angle and positioning of Hoyt's head vis-à-vis the sun determines shadows that haunts Hoyt's visage.
"This is going nowhere. Absolutely nowhere. There's more to life than . . ." Sally waves an arm.
The engine of the Dodge Ram is idling. Sally is poised to get back in her truck. There's purpose in her visit and it's obvious she wants to get that purpose and this visit over with as quickly as possible.
Hoyt's eyes have followed Sally's hand, which is at the end of Sally's waving arm, but then the arm and the hand come down to go limp next to Sally's side.
Hoyt moistens his lips with his tongue and looks around. His lips are chapped.
Sally waits. The cat seems to be waiting too. The cat's eyes are hazel. From somewhere in that vast sky a raven caws. Such a clear, vivid sound.
Sally climbs onto the driver's seat, door remaining open. Hoyt and Sally look at each other. A hummingbird comes whizzing by, translucent green and red like a glitzy dart. The bird's on its way to a feeder that hangs at the end of an eave where the patio's tin roof leaves off.
"I've been coming out here for two and a half years and nothing has changed, except I'm getting older."
"I don't doubt it, because I'm the same. But I live here."
She looks at him anew. He kind of smiles.
"Are you going to miss me?"
"I think so," he tells her.
"Do you know who I am, Hoyt? Do you know who Sally Fisher is?"
"Well, yeah. You're Sally Fisher."
She ejects a sigh. Her hair is cropped short, a bowl-like configuration. Thick and black and glossy. Her eyebrows are very distinct. She's lost weight.
"Don't you aspire to be something?"
He kind of grins, crookedly.
The cat has come over and is looking up into the cab of the truck, like maybe it's thinking of jumping onto the cab's floor, near Sally's feet, which are wedged into a pair of new huaraches, toenails fire engine red.
"What is it that you have in mind?" Hoyt asks, voice dry and sandy.
"Some sort of viable career, or just a job, a regular job. Go to work at real place where real paychecks are issued. Maybe get a house, start a family . . . like other people."
"Domesticity."
"Yeah. What's wrong with that?"
A wry expression comes to Hoyt's face. He shifts his weight from foot to foot. He's wearing khaki shorts that have a lot of pockets. Sally is wearing the same kind of shorts.
"I thought artists were supposed to be bohemian types."
"That went out with the beatniks, or maybe the hippies. People don't want to be poor anymore. They want to be rich."
Hoyt nods slowly, Adam's apple bulging. On his torso there's a maroon T-shirt with the sleeves cut off, ends of his shoulders exposed.
A roadrunner, which hangs in the vicinity beyond the patio, has stalled Sally's glance in that direction. The bird is mischievous. It sometimes taunts the cat. Sally's eyes and mind return to the subject at hand.
"I'm making money. More decorators are buying my work and I've had a couple of shows at galleries. I'm moving in different circles now. I want to get out of my apartment. I'm thinking about a mortgage. I told you all this."
"And what did you do or say?"
"I listened."
Sally closes the door of her truck. The window is down. The cat walks away in the direction of the singlewide that's offering shade on its east side.
Sally shifts from park to drive and accelerates slowly and turns around. Hoyt watches and so does the cat while lying on its side in the shade. Sally swings onto the graded dirt road and accelerates with force. A spray of grit at the underside of her vehicle confirms rapid movement. Swirls of gray dust pester the truck's tailgate. In the distance, on the other side of a knoll at a meager junction where a mailbox dwells, the tires of her pickup truck will encounter a true washboard surface. Two miles on, the Dodge Ram will stop jittering when its tires find purchase on macadam. But for now, Sally glances at a side mirror and sees Hoyt standing. Tears drizzle on Sally's sun-brown cheeks. Hoyt told her the other day: "Let's hope this is the future," and waved an arm.
MICHAEL ONOFREY grew up in Los Angeles, but currently lives in Japan. His stories have appeared in Cottonwood, Evansville Review, Kestrel, Natural Bridge, Oyez Review, Terrain.org, and Weber - The Contemporary West, as well as in other fine places. A novel, Bewilderment, was published in 2017 by Tailwinds Press.
Chila: Tell us how you came up with the idea for this story & its interesting introductory section.
Michael: I have a computer file where I put ideas for stories. These ideas can come up anywhere and at any time, so they usually get jotted down on scraps of paper, from which they go into the computer file. If I want to write a story but don't have an idea, I look at that file. That's where "Future" came from. Its first two lines were taken from that file. After that I kept adding ideas, which constitute the first section of the story. As I got more into that first section, a narrative began to develop. The second and third sections of the story pick up that narrative. If I had treated this piece like I do most other pieces, I would have gone back and brought the first section into a more usual narrative form. But I, like a lot of other people who write, like to try new things, which often means taking risks. In looking at that first section, I saw metafiction, reader being made aware of storytelling. Sometimes I like that, usually I don't. In this case, though, there was something else, and it was seeing how a story develops, and not just on paper but in one's mind.
Chila: Does living in Japan influence your writing, and if so, how?
Michael: No, I don't think it influences my writing. Of course there have been stories I've set in Japan, but anyone visiting here might very well come up with stories set here.
Chila: What is your next major project?
Michael: "Major," as in time consuming, is another novel. But "immediate," as in next project, that'd be short fiction, several short stories. I like to go back and forth between short fiction and long fiction because it breaks things up. Regarding ideas for long or short fiction right now—I don't have any. I have to consult my "ideas & notes" computer file.
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What Are The Types Of Causes?
What are the two types of causes and effects?
What are the first causes in philosophy?
Who Discovered Cause and effect?
What is the formal cause of a house?
What is an example of effect?
How do you explain cause and effect to students?
What are the four types of causes?
What are the 4 causes according to Aristotle?
What is causes and effect?
What is final cause in ethics?
What are the 3 types of cause and effect?
What is the material cause of a human?
What is Aristotle's substance?
What are the four requirements for claiming causality?
What is Aristotle form?
What are the 5 arguments for the existence of God?
Is God the first cause?
Types of Cause and EffectCause-and-Effect Relationship.
A cause-effect relationship is a relationship in which one event (the cause/ "X") makes another event happen (the effect/ "Y").
Common-Cause Factor.
Reverse Cause and Effect Relationship.
Accidental Relationship.
Presumed Relationship..
First cause, in philosophy, the self-created being (i.e., God) to which every chain of causes must ultimately go back. The term was used by Greek thinkers and became an underlying assumption in the Judeo-Christian tradition. … Aquinas argued that the observable order of causation is not self-explanatory.
AristotleThe emphasis on the concept of cause explains why Aristotle developed a theory of causality which is commonly known as the doctrine of the four causes. For Aristotle, a firm grasp of what a cause is, and how many kinds of causes there are, is essential for a successful investigation of the world around us.
§The bricks or wood out of which it is made are its material causes. §The way in which these materials are organized such that it is a house is its formal cause. §The builders are the efficient cause of the house. They organize the materials into the form of a house.
For example, you can feel the effects of a cold or an earthquake, and the sun coming out can have a positive effect on your mood. Some synonyms of effect include words like result, repercussion, consequence, outcome, aftermath, and the noun version of impact.
In essence, cause is the thing that makes other things happen. Effect refers to what results. It is the what happened next in the text that results from a preceding cause. To put it concisely, cause is the why something happened and effect is the what happened.
Aristotle's Four CausesMaterial Cause – the stuff out of which something is made.Formal Cause – the defining characteristics of (e.g., shape) the thing.Final Cause – the purpose of the thing.Efficient Cause – the antecedent condition that brought the thing about.
Aristotle's very ancient metaphysics often centered on the four causes of being. They are the material, formal, efficient, and final cause. According to Aristotle, the material cause of a being is its physical properties or makeup. The formal cause is the structure or direction of a being.
The Purpose of Cause and Effect in Writing A cause is something that produces an event or condition; an effect is what results from an event or condition. The purpose of the cause-and-effect essay is to determine how various phenomena relate in terms of origins and results.
End or Purpose: a final cause is that for the sake of which a thing is changing. A seed's end is an adult plant.
In this case, there are three main kinds of causes:Immediate Cause: This is the cause that has occurred most recently. Consider the example of snowfall. … Principal Cause: This is the main cause responsible for an event. … Independent cause: This is the cause that is independent of the events.
These causes are material, formal, efficient and final. The material cause is what something is made out of. The human body of made up of cells. Wooden boxes are made up of wood.
Aristotle analyses substance in terms of form and matter. The form is what kind of thing the object is, and the matter is what it is made of. … Aristotle acknowledges that there are three candidates for being called substance, and that all three are substance in some sense or to some degree.
Defenders of religion have countered that the question is improper: We ask, "If all things have a creator, then who created God?" Actually, only created things have a creator, so it's improper to lump God with his creation. God has revealed himself to us in the Bible as having always existed.
The first three criteria are generally considered as requirements for identifying a causal effect: (1) empirical association, (2) temporal priority of the indepen- dent variable, and (3) nonspuriousness. You must establish these three to claim a causal relationship.
Thus according to Aristotle, the matter of a thing will consist of those elements of it which, when the thing has come into being, may be said to have become it; and the form is the arrangement or organization of those elements, as the result of which they have become the thing which they have.
Thus Aquinas' five ways defined God as the Unmoved Mover, the First Cause, the Necessary Being, the Absolute Being and the Grand Designer. It should be noted that Aquinas' arguments are based on some aspects of the sensible world. Aquinas' arguments are therefore a posteriori in nature.
Aquinas argued that our world works in the same way. Someone or something must have caused the world to exist. The cause is God, the effect is the world. Aquinas stated that this cause (which is outside our world) is the first cause – that is, the one that started everything.
Question: Can You Put Resin Over Sharpie?
Can you clear coat over Sharpie? A coat of vinyl sealer
Quick Answer: Is Lightroom Classic Going Away?
Which Lightroom version is best? #1 Lightroom CC is
Quick Answer: How Long Taxi From Manhattan To JFK?
How long does it take from Manhattan to JFK airport?
How Do I Discern God'S Voice?
How do you know if God is trying to tell you something?
How Long Has The LOFI Girl Been Studying?
What is LOFI girl studying? LoFi study beats have become


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Vikram leads Aishwarya Rai Bachchan by hand as she thanks audience for Ponniyin Selvan's success, keeps Aaradhya close. Watch
Vikram leads Aishwarya Rai Bachchan by hand as she thanks audience for Ponniyin Selvan's success, keeps Aaradhya close. Watch
Aishwarya Rai Bachchan expressed her gratitude after Ponniyin Selvan witnessed a successful weekend at the box office. She was accompanied by daughter Aaradhya at a special screening of the film.
New Delhi | Updated: October 4, 2022 08:33 IST
Aishwarya Rai Bachchan in Ponniyin Selvan.
The Ponniyin Selvan cast has received much love and adulation from fans and paparazzi. An overwhelmed Aishwarya Rai Bachchan expressed her gratitude as the film crossed Rs 200 crore worldwide in just three days. In a new video shared by a theatre chain, the actor, with daughter Aaradhya Bachchan by her side is seen exiting the theatre after the screening of the film. She thanks the paparazzi and the audience for the film's success as co-star Vikram led her towards the fans. She folded her hands and blew kisses amid hoots and cheers. She is later seen driving away in the car, waving at fans. In another part of the clip, Trisha, exits the theatre amid much cheer, while fans throng the lanes to get a glimpse of her. Earlier, Karthi had penned an emotional note, thanking the cast and crew for crafting such a visual spectacle.
Also Read |Vikram conveys 'heartfelt' thanks to Mani Ratnam, team for making Ponniyin Selvan. Watch
The film, based on Kalki's works, had a bumper opening at the box office, earning over Rs 200 crore worldwide. The film, directed by Mani Ratnam, is edging towards the Rs 100 crore club domestically and the current collection stands at around Rs 69 crore. The numbers are expected to increase further during the festive season.
The historical drama, which is divided into two parts, is a fictionalised tale set in the Chola kingdoms. Aishwarya plays the role of Queen Nandini, while Vikram essays the role of Aditya Karikalan. Jayam Ravi plays the role of Rajaraja Chola I, and Karthi is Vanthiyathevan, the warrior prince of Vaanar Clan. The story revolves around the Cholas and their determination to win against the advancing Rashtrakuta army, amongst other threats.
The second part will release in 2023. Interestingly, both the parts were shot in 150 days—a fact that had earlier left SS Rajamouli, the director of the Baahubali films, rather shocked. However, while Ponniyin Selvan has endured comparisons to RRR and Baahubali ever since its announcement, Mani Ratnam had always maintained that it will be starkly different altogether. At the audio launch of Ponniyin Selvan 1, Ratnam said, "Subhashakran (producer of Ponniyins Selvan) asked me if it would be like Baahubali. I said no it won't be. He later asked if it would be like Padmaavat. I said no. Then he asked how else will it be. I said I am planning to make like what Amarar Kalki had written."
Bengaluru Highlights: Mysuru Dasara procession to be held today; Bengaluru sees ban on liquor sales


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Szopa (dodatkowa nazwa w j. kaszub. Szopa) – wieś kaszubska w Polsce, położona w województwie pomorskim, w powiecie kartuskim, w gminie Sierakowice, na Pojezierzu Kaszubskim i na obszarze Kaszubskiego Parku Krajobrazowego położona. Wieś jest częścią składową sołectwa Bącka Huta. Na wschód od wsi znajduje się rezerwat przyrody Staniszewskie Błoto.

W latach 1975–1998 miejscowość administracyjnie należała do województwa gdańskiego.

Integralne części wsi

Przed 2023 r. częściami wsi Szopa były Bór i Łączki, od 1 stycznia 2023 wsie.

Z kart historii
Od końca I wojny światowej wieś ponownie znajdowała się w granicach Polski (powiat kartuski). Do 1918 roku obowiązującą nazwą niemieckiej administracji dla Szopy była niem. Schoppa. Podczas okupacji niemieckiej w 1942 r. nazwa Schoppa została przez nazistowskich propagandystów niemieckich (w ramach szerokiej akcji odkaszubiania i odpolszczania nazw niemieckiego lebensraumu) zweryfikowana jako zbyt kaszubska i przemianowana na nowo wymyśloną i bardziej niemiecką – Schöppen.

W szkole w Szopie dzieci uczą się m.in. języka kaszubskiego.

Zobacz też
 Mirachowo
 Mojusz
 Sierakowice

Przypisy


text:
TLGY Acquisition Corp.
We intend to focus on targets in industries where we believe our management team and our founder's expertise will provide us with a competitive advantage, including biopharma or technology enabled business-to-consumer ("B2C") industries globally. We believe the innovations in these sectors that have emerged in recent years, partly as a response to the broad social, economic, and behavioral changes arising from the COVID-19 global pandemic, provide attractive opportunities to target high growth companies with technology and business model innovation. For example, by virtue of our team's industry network and our founder's recent investments, we have turned our attention towards certain sub-segments in healthcare, including neurology and rare diseases, where we believe we can find attractive targets for our business combination. (Incorporated in the Cayman Islands)
While we will target companies globally, we believe that our team's strong ties to Asia gives us an advantage in sourcing Asia-originated biopharma companies with global aspirations for the purposes of a business combination in the U.S. market. We believe favorable innovation and regulatory trends in Asia should position us well for such opportunities. In B2C technologies, we will look for ways to capitalize on our team's previous work with and/or investments; for example, we will leverage our experience in Asian gaming companies and focus on the implications of the big changes that are taking place in the industry due to the surge in the post-COVID consumer demand for a wide range of virtual entertainment and lifestyle products. We will not undertake an initial business combination with any entity with principal business operations in China (including Hong Kong and Macau).
Mr. Jin-Goon Kim is our founder, chairman and CEO. Mr. Kim has two decades of senior leadership experience in private equity investment and as a serial transformational CEO in industry-leading public and private companies. From 2006 to 2016 Mr. Kim was with TPG Capital, a leading global private equity firm, where he served as a partner and a member of its Asia investment review committee. In his capacity as a TPG partner, Mr. Kim also served as a CEO or transformation leader of multiple TPG portfolio companies, often in parallel. Before joining TPG Capital, Mr. Kim served from 2002 to 2006 as president of Dell Korea, the Korean affiliate of Dell, a global leader in hardware, software and services with more than $60 billion in annual sales in 2020. He successfully led the implementation of Dell's direct model in Korea for the first time, firmly establishing Dell as a leading player in a market where it had previously struggled to secure a meaningful market presence or to build a profitable business. Mr. Kim earned an MPP from the Kennedy School of Government at Harvard College, a diploma from the Hopkins-Nanjing Centre, and an AB in East Asian Languages and Civilizations and Government from Harvard College.
(Note: TLGY Acquisition Corp. upsized its SPAC IPO at pricing on Nov. 30, 2021, to 20 million units, up from 17.5 million units, at $10 each to raise $200 million.)
Industry: BLANK CHECKS
Address 4001 Kennett Pike, Suite 302 Wilmington, DE 19807
View Prospectus: TLGY Acquisition Corp.
Market Cap $243.75mil
Revenues $0 mil (last 12 months)
Net Income $0 mil (last 12 months)
Symbol TLGYU
Exchange NASDAQ
Shares (millions): 20.0
Price range $10.00 - $10.00
Manager / Joint Managers Mizuho Securities
CO-Managers Baird
Expected To Trade: 12/1/2021
Status: Priced


What is breathwork? Breathwork is a general term for various breathing techniques used to promote physical, mental, emotional and spiritual wellbeing.
Professional Breathworker Practitioner and Facilitator Training programme certifies you to the international breathwork professional standards founded since 1999 from 23 trainings become a practitioner!


text:
Deloitte Life Magazine has been saved
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An Article Titled Deloitte Life Magazine already exists in Saved items
Deloitte Life Magazine
Stories about our work and our people
It's a celebration of our people and the shared experience we know as the Deloitte life.
Work, life, and leadership driven by purpose
Having forged a successful career in the Technology sector, Deepa Purushothaman, principal in Deloitte Consulting LLP's Social Impact service line and national leader of Deloitte's Women's Initiative, reflects on her own experiences in discovering her voice. She discusses her journey to becoming true to her sense of purpose and finding ways to bring purpose to her daily work life.
Using many small moments to make a big impact: Just 10 weeks into her new position as a senior consultant in Deloitte Consulting LLP's Human Capital Organizational Transformation & Talent practice, Elizabeth Lascaze urged her fellow Marshall grads to apply the now-familiar business concepts of "margin" and "scale" to their own lives. By building on the outer limits—the margin—of those who had gone before, and leveraging scale in the form of the 300,000+ global network of USC Trojans, they, too, could make an impact on the world.
Touching more lives, broadening patient care: Chip Newton, senior manager, Deloitte Consulting LLP, and his Deloitte teammates helped prepare a presentation for Dr. Jose Rodriguez-Diaz, AID Atlanta's chief executive officer, to deliver to the White House Office of National AIDS Policy.
Going the distance: Whether it's in the water, on a bike, or running down a road, Andi Ramer is committed to determining just how far she can go. "When I started, I couldn't even run to the corner and back," she said.
Thinking big, starting small: George Roche used a sabbatical to sharpen his thinking about how free enterprise can have a social impact in the developing world
Heart of the matter: With her husband hospitalized and awaiting a heart transplant, Andrea Hampton found the strength and determination to spread the word about organ donations.
Giving a year, getting a lifetime: Deloitte helps City Year put at-risk students – and volunteers – in a position to succeed.
Where there's a need, fill it: Through community involvement, Deloitte's Jack McFadden is a real STAR.
Global perspectives become local solutions: The U.S. Global Office Fellows Program broadens perspectives, networks, and skills.
A great idea takes flight: An unsuccessful search for a great glass of wine at an airport inspired a new way of thinking for Deloitte Consulting alumnus Doug Tomlinson and a new experience for air travelers.
Hitting all the right notes: From the bright lights of the stage to the critical thinking of a marketing project, music is integral to Katherine Fox Wolf's life.
Going places: Two professionals share their sabbatical experiences.
Out of this world: A childhood fascination with space exploration morphs into a renowned collection of 'Star Trek' memorabilia.
Designed for the way we work: Coming to an office near you – Next Generation Workplace: a dynamic, fresh, and increasingly collaborative space that strengthens our culture and brand.
Born with the fire to inspire: Through his optimism, charisma, and indomitable spirit, Sai Prasad Vishwanathan provides a powerful example.
Never too early to innovate: While developing a new idea for the Federal practice, seven first-year consultants discover the value of innovation, networking, and friendship.
Magic mountain: As a volunteer, Maryann Zeira helps people with disabilities make fear disappear.
About Deloitte Life
On the pages of Deloitte Life, you will find a collection of our stories – profiles on our people and their special talents, and an inside look at our work, achievements, and values. Although developed as an internal publication, Deloitte Life is also enjoyed by families, friends, potential hires and others who appreciate the Deloitte culture and commitment to innovation, excellence, and community.


The table below contains all items that came with the Welcome amiibo update for Animal Crossing: New Leaf.
Click on the "Info" button to get more information on using the table.
Item Name is the name of the item as it appears in the in-game catalog, except that the first letter of most words has been capitalized.
Category shows what type of item it is. Eg., furniture, flooring, wallpaper, clothing, handheld or litter.
Utility shows whether and how an item can be used.
Origin shows where or how the item can be obtained.
Cost shows the cost of an item. Some items are free, some can be ordered for Bells from the catalog machine in the Nookling's store, a few can be bought with Play Coins. All the other items cost MEOW Coupons, and can be found at Harvey's, or be ordered from an RV. You can filter on any of these four currencies.
Refurbishable shows whether an item can be refurbished by Cyrus, but it doesn't show all the refurbishment options.
Vanilla shows whether an item can be obtained without having to WiFi, and without having to buy Happy Home Designer, amiibo cards or amiibo figurines.
Interactive shows whether you can interact with an item, for instance if anything happens when standing in front of it and pressing "A" on your console, by sitting or sleeping on it, or by using it as a table.
Wall shows whether an item can be hung on the wall.
On Top shows whether an item can be placed on top of another item.
Mat shows whether an item can be placed on the floor of your house or a museum room and you can walk over it.
By default, the table is sorted by Item Name. Click on any other column heading to sort the information differently. Clicking the same column heading again will reverse the sort order.
For a more extensive or specific search, a filtering function has been added. To use this you will need to enter information in the boxes titled Filter/Search String and Column. The filter string is not sensitive to cases or accents. Filter the 6 rightmost columns using "1" or "0" as filter string.
fruit-panel wall Wallpaper Puzzle League - Success in "taking charge"


text:
Curro Vargas est une zarzuela en trois actes de Ruperto Chapí, sur un livret de Joaquín Dicenta et Antonio Paso y Cano, basée sur le roman El niño de la bola de Pedro Antonio de Alarcón et créée au Théâtre Circo Parish de Madrid, le .

Personnages

Synopsis
L'action du premier acte se passe dans une oliveraie de las Alpujarras. Un groupe d'hommes et femmes sont en train de ramasser les olives. Après cette scène de groupe, Soledad et sa mère, Doña Angustias ont une conversation qui expose au public la situation. Le père de Soledad aspire pour sa fille à un fiancé riche, bien qu'elle aime Curro Vargas qui, de son côté, la désire très fort. Devant la situation, Curro Vargas choisit de la laisser pour chercher fortune dans d'autres contrées, lui demandant de l'attendre et lance l'anathème: "Que personne n'aspire à Soledad, puisque Soledad est à moi". La peur qu'inspire Curro dans le village, fait que personne n'ose s'approcher d'elle, à l'exception de Mariano. Curieusement, Soledad se donnera à Mariano par orgueil, parce qu'elle ne veut pas être la propriété de quelqu'un. Ceci est la base de son comportement, soumis pour une part à son caractère qui refuse d'accepter des contraintes et d'un autre côté à son amour pour Curro qu'elle n'a pas oublié et qui la poursuit comme un fantasme, mais elle n'est pas heureuse avec son mari. A lieu une scène comique entre Rosina, Timoteo et le capitaine Velasco. Arrive le Père Antonio qui raconte l'histoire de Curro. Ce dernier est fils d'un riche de la région qui a dilapidé sa fortune aidé par un administrateur qui n'était autre que le père de Soledad. Curro a été jeté à la rue par le père de celle-ci. Recueilli par le prêtre, il est tombé amoureux de la fille qui se débat entre son amour à l'égard de Curro, et sa dépendance vis-à-vis de son père. Curro décide d'aller à la recherche de la fortune et de revenir la chercher. Ils sortent et la mère Emplastos annonce que Curro vient de revenir. La première chose que fait celui-ci, est de prendre des nouvelles de Soledad et Curro à nouveau maudit la jeune femme.

Le second acte commence dans la grand rue du village. Après une scène d'ensemble, la dame Angustias s'adresse au père Antonio lui demandant qu'il intervienne auprès de Curro pour que celui-ci ne mette pas en œuvre sa vengeance. À ce moment, elle révèle au père Antonio que la situation a changé, qu'il n'y fasse pas cas bien qu'il ait une justification pour son attitude. Simultanément apparaît la figure de Timoteo, prévue pour un moment comique. Lui aussi amoureux de Soledad, chante dans une scène où il manifeste sa peur devant la fureur de Curro. La mère Emplastos informe Soledad que Curro s'apprête à faire quelque chose. Apparaît Mariano, étranger à la situation. Il chante un duo dans lequel il jette à figure de Soledad que bien qu'il reste avec elle, il en aime une autre. Soledad elle-même a la sensation de plus en plus forte que l'on s'achemine vers un final tragique. Curro en voyant Soledad, s'approche d'elle avec un couteau avec l'intention de la tuer. Le père Antonio le retient, lui rappelant la mémoire de son père. Soledad s'évanouit pendant que le chœur de jeunes filles chante un hymne à la Vierge.

Le premier tableau du troisième acte représente l'avant-salle de la sacristie de l'église du village. Après une scène comique entre le capitaine Velasco et Timoteo, contrepoint à la situation dramatique précédente, le père Antonio et Curro ont une conversation. Le premier se trouve impuissant à arrêter le second, mais après avoir utilisé toutes ses armes dialectiques, il le convainc de pardonner à Soledad et de partir. Quand celui-ci est sur le point de s'en aller, il reçoit une lettre de Soledad dans laquelle elle lui déclare qu'elle l'a toujours aimé et que ce sont d'autres types de raisons qui l'ont obligé à se marier avec Mariano. Devant ce nouvel élément, la situation change et Curro chante sa célèbre romance "¡Qué siempre me ha querido!" (Elle m'a donc toujours aimé). Le second tableau se passe sur une petite place proche du village. On se prépare à organiser un bal dans lequel chaque jeune, dans une sorte de vente aux enchères, «achète» la fille qui sera sa partenaire pour danser. Le chœur manifeste son désir de voir s'éloigner la situation tragique qui se rapproche, malgré les tentatives de rébellion de Mariano. Durant le bal, démontrant son amour, Soledad se laisse tuer par Curro qui la poignarde. Mariano voyant le geste, s'adresse à Curro et également le tue, sans que ce dernier ne lui oppose résistance.

Œuvre de Ruperto Chapí
Zarzuela
Opéra créé à Madrid
Opéra des années 1890


text:
Arts All Stars
Arts All-Star: Ashlyn Hilts
April 28, 2020 at 8:05 AM EDT - Updated April 28 at 8:05 AM
CHAUMONT, N.Y. (WWNY) - Ashlyn Hilts sometimes uses music as an escape.
"I mean, we live in a really crazy world, especially now," the Lyme flutist said.
She's the 7 News Arts All-Star for April 27, 2020.
Playing what she wants for as long as she wants "is a really good feeling, it's something that distracts me from the craziness of the world."
She wants to spend her first two years after high school at Jefferson Community College, but after that is up in the air. She hopes to become an occupational therapist. Watch the video to learn more about her.
Academic All-Star: Madison Munn
Arts All-Star: Anna Western
Published December 22, 2020 at 10:35 AM
Career-Tech All-Star: Drew Paluch


text:
Leading homebuilder supports charity that grants the wishes of children living with life threatening illness
Added by Love Business East Midlands | 22 December 2020
David Wilson Homes has donated £1,000 to a charity dedicated to making the dreams of children with life threatening illnesses come true.
The Northampton-based developer's donation will go towards granting wishes for a number of children which will transform their and their family's lives.
When You Wish Upon a Star was founded in 1990 by Barbara White, after she was inspired by a seriously ill four year old with a dream to meet Mickey Mouse. Barbara then decided that she wanted to bring smiles to the faces of many more brave and courageous children.
The charity helps children in a variety of ways. For example, some children wish to be a fairy princess or soldier for the day, some want meet celebrities or sporting heroes. Others wish for a laptop to keep in contact with their friends and family whilst in hospital. One of the most popular wishes remains the exciting opportunity to swim with dolphins and meet all their favourite characters in Disney World, Florida.
Alexa Wigfield, Regional Fundraiser at When You Wish Upon a Star, said:
"During this difficult time lots of our events have been cancelled which has caused our funds to deplete. To hear about David Wilson Homes' donation was much needed news for us.
"When a wish is granted it helps create magical memories for the family and allows them to put their child's illness on hold as they have fun and create precious memories.
"On behalf of everyone at When You Wish Upon a Star we would like to say a big thank you to David Wilson Homes for helping us to continue granting magical Wishes for these children who are having a really tough time."
John Dillon, Managing Director at David Wilson Homes South Midlands, said:
"We are so pleased to be able to support When You Wish Upon a Star and the fantastic work they are doing.
"It is important to us a leading housebuilder to recognise and support local charities and organisations who help the communities near our developments."
To find out more about When You Wish Upon a Star, please visit https://www.whenyouwishuponastar.org.uk/.
For more information about David Wilson Homes, call the sales team on 033 3355 8486, or visit https://www.dwh.co.uk/.


What is an Interlibrary Loan Request?
The Library provides Interlibrary Loan as a supplemental service to obtain items you want that are not owned in The Library's collection. The Library can often borrow additional items from libraries in our district service area, from around the state, and from across the nation.
Check on your Interlibrary Loan requests in your Encore account. A few days after you have submitted a request, log in to your account and click on "Interlibrary Loan." You will see your requested titles and the status. It will say "Awaiting Arrival" when The Library is waiting for the item, and "Ready for Pick-up" when it is ready for checkout at the home library listed on your account.
Use Interlibrary Loan to request items that are not owned by The Library. Please check The Library's catalog to see if we have local resources before requesting Interlibrary Loan.
You may submit up to 5 Interlibrary Loan requests per month. Note: The Library processes Interlibrary Loan requests from all public libraries in our district service area, so requests submitted via other public libraries in Cumberland, Dauphin, and Perry County are included in the limit of 5 per month.


The largest population-based retrospective study to date comparing multimodal therapies in advanced prostate cancer shows that primary treatment with radical prostatectomy (RP) followed by radiotherapy (RT) offers a significant survival advantage but higher rates of erectile dysfunction and urinary incontinence.
The study, led by Grace L. Lu-Yao, PhD, MPH, of the Sidney Kimmel Cancer Center–Jefferson Health, in Philadelphia, Pennsylvania, was published online September 25 in Cancer.
The analysis of Surveillance, Epidemiology, and End Results–Medicare data from 13,856 men with locally advanced or regionally advanced prostate cancer showed that the adjusted 10-year prostate cancer–specific survival rate was 89% in those treated with RP and RT, compared to 74% in men who received RT plus androgen deprivation therapy (ADT).
The adjusted 10-year overall survival rate was 64% in men who underwent RP plus RT, compared to 48% in those who received RT plus ADT.
At a median follow-up of 14.6 years, this overall survival advantage was present regardless of tumor stage or Gleason score, the researchers say. Men without lymph node metastasis benefited the most, the study showed.
In a statement issued by Jefferson Health, Lu-Yao noted the controversy surrounding multimodal therapies.
Still, improved survival came at a cost to quality of life. The analysis showed that men who underewnt RP plus RT had significantly higher rates of erectile dysfunction compared to men treated with FT and hormone therapy (28% vs 20%; P = .02).
In addition, the rate of urinary incontinence was more than twice as high in men treated with RP plus RT compared to those who underwent RT plus ADT (49% vs 19%; P < .0010). Men treated with RP plus RT also had higher rates of bladder neck contractures and urethral strictures compared to men who underwent RT plus ADT (38% vs 18%).
Although the use of aggressive RT after surgery began more than 2 decades ago, the proportion of men who undergo prostatectomy plus RT has decreased significantly since then, Lu-Yao noted. "There were trade-offs for the survival advantages," she pointed out.
The study showed that of the 2189 deaths in the cohort, 702 were secondary to prostate cancer. By 10 years, most men with T4N1M0 disease had died as a result of prostate cancer, regardless of treatment, the researchers say.
Notably, the analysis revealed that clinicians were not following treatment guidelines for high-risk prostate cancer recommended by the National Comprehensive Cancer Network and the European Association of Urology/European Society for Radiotherapy and Oncology. Both recommend multimodal treatment, including RP and RT, and RT plus ADT.
Rather, researchers discovered that half of the entire cohort had been treated with a single intervention and that 20% of the cohort of men aged 65 years or older had received no treatment at all within 6 months of diagnosis.
"Our data can't tell us the reason for this deviation from guidelines, and further studies are needed," said Lu-Yao. "Prostatectomy is an unpopular treatment," she added.
In men who received multimodal therapy, 6.1% received RP plus RT, and 23.6% were treated with RT plus ADT. Men who were more likely to receive RT plus ADT tended to be older, unmarried, have significantly more comorbidities, and have tumor fixation to adjacent structures.
The analysis also showed that younger men with fewer comorbid conditions and extracapsular extension (T3aN0M0) or seminal vesicle invasion (T3bN0M0) without regional lymph node involvement were more likely to receive RP plus RT. Men with regional lymph node involvement and extracapsular extension or seminal vesicle invasion were also more likely to undergo RP plus RT than RT plus ADT.
"Although we found RP as a primary intervention to be associated with more favorable survival outcomes than RT in this high-risk population, the questions, as other investigators have suggested, should focus not on which modality is best," the authors emphasize. Instead, they say, the focus should be on optimizing treatment timing and intensity and integrating more effective systemic therapies with optimal local treatments.
When approached for comment, Jorge Garcia, MD, director of the advanced prostate cancer research program at the Cleveland Clinic, Ohio, said that with novel agents, "some men with oligometastatic prostate cancer can achieve durable responses, if not cure.
"Traditionally, the standard of care for high-risk prostate cancer without positive nodes in men who elect surgery is radical prostatectomy alone, followed by ether adjuvant radiation therapy or salvage radiation therapy plus ADT at the time of failure," Garcia noted. Most are treated with either high doses of the oral androgen receptor inhibitor bicalutamide (Casodex, AstraZeneca) for 2 years, or ADT with testosterone suppression for 6 months.
For men who elect to have RT instead of surgery, the current standard of care is 2 years of ADT plus RT, he said.
Garcia emphasized the importance of a multidisciplinary approach in men with high-risk prostate cancer. A urologist, a radiation oncologist, and a medical oncology team are needed to maximize treatment outcome in these patients, he said.
Tanya Barauskas Dorff, MD, clinical professor in the Department of Medical Oncology and Therapeutics Research at City of Hope in Duarte, California, agreed. "Overall, the conclusions fit with the shift in our thinking about local control being critical," she told Medscape Medical News.
The need for multimodal therapy with RP plus RT in patients with locally advanced prostate cancer is becoming increasingly recognized, said Dorff, who is head of the genitourinary cancers program.
RT plus ADT "remains valuable," she added.
These data add support to combining therapies for maximum advantage, commented Leonard G. Gomella, MD, chair of the Department of Urology at the Sidney Kimmel Cancer Center – Jefferson Health. He was not involved in the current study.
Gomella emphasized that men with localized prostate cancer with adverse features, such as a high Gleason score or extension outside the prostate, should be considered for multimodal therapy.
Studies investigating the use of surgery, RT, and hormonal therapy in high-risk prostate cancer are producing evidence that multimodal therapies provide benefit in terms of cancer control and progression, Gomella pointed out. Technical changes in surgery and RT over the past decade have limited adverse side effects associated with these therapies, and new tools, such as genomic markers and improved imaging, are making a clinical impact in more aggressive localized disease.
Major clinical improvements in the use of combined therapies have created models of success in other cancers, including lymphoma and bladder cancer, said Gomella. "Radiation therapy combined with hormonal therapy represents a standard for many men with prostate cancer," he said.
The study was funded by the National Cancer Institute, the New Jersey Health Foundation, and the Rutgers Cancer Institute of New Jersey. Dr Lu-Yao has disclosed no relevant financial relationships. Other authors have financial ties to OPKO Health and Merck. Dr Garcia has relationships with Janssen, Sanofi, and Bayer. Dr Dorff and Dr Gomella have disclosed no relevant financial relationships.


text:
Miles5102550100150200
Showing all 14 locations
5705 Patterson Ave, Richmond, VA 23226, USA
3400 Pump Rd, Henrico, VA 23233, USA
10200 W Broad St, Glen Allen, VA 23060, USA
9507 Woodman Rd, Richmond, VA 23228, USA
10606 Patterson Ave, Henrico, VA 23238, USA
1102 N Parham Rd, Richmond, VA 23229, USA
1807 Staples Mill Rd, Richmond, VA 23230, USA
2560 Sheila Ln, Richmond, VA 23225, USA
200 N Robinson St, Richmond, VA 23220, USA
4844 S Laburnum Ave, Henrico, VA 23231, USA
11665 Midlothian Turnpike, Midlothian, VA 23113, USA
12026 Southshore Pointe Dr, Midlothian, VA 23112
11341 Nuckols Rd, Glen Allen, VA 23059, USA
2800 W Marshall St, Richmond, VA 23230, USA
Puritan Cleaners locations
Puritan Cleaners is committed to serving members of the Westhampton community with in-store and free home delivery dry cleaning services. We are located on Patterson Avenue near Libbie Avenue and happily serve the areas of the West End, Westhampton, Windsor Farms, and other areas in west Richmond.
Puritan Cleaners is committed to serving the Short Pump community with in-store and Free Home Delivery dry cleaning services. Because we are right at Short Pump Crossing Shopping Center, we are able to serve the areas of Church Run, Wellesley Ridge, Rockville, and all of Short Pump. We hope to serve you soon!
Puritan Cleaners is committed to serving members of the Innsbrook community with in-store and free home delivery dry cleaning services. Because we are right off Broad Street, we are able to serve the areas of Innsbrook, Cross Ridge, and most of north Henrico.
Puritan Cleaners is committed to serving members of the Glen Allen community with in-store and free home delivery dry cleaning services. We are located at the intersection of Hungary and Woodman, so we are able to serve the areas of Glen Allen, Lakeside, Elmont, and all the way up to Ashland.
Puritan Cleaners is committed to serving members of the Patterson community with in-store and free home delivery dry cleaning services. We are located at the intersection of Patterson Ave. and Pump Rd, and we serve the areas of Raintree, Bennington Ridge, and Crown Grant
Puritan Cleaners is committed to serving members of the Tuckahoe community with in-store and free home delivery dry cleaning services. Because we are located at the intersection of Parham and Patterson, we are able to serve the areas of Tuckahoe and Lorraine.
Puritan Cleaners is committed to serving members of the Staples Mill community with in-store and free home delivery dry cleaning services. We are located right off Staples Mill Rd and happily serve the areas of Willow Lawn, Near West End, Westhampton, Dumbarton, and other areas along Broad Street.
Puritan Cleaners is committed to serving members of the Bon Air community with in-store and free home delivery dry cleaning services. Because we are right off Chippenham Parkway, our Chippenham Forest Location is able to serve the areas of Stony Point, Forest Hill, Westover Hills, Chippenham Villages, and the rest of Bon Air.
Puritan Cleaners is committed to serving members of the Fan District with in-store and free home delivery dry cleaning services. Because we are located on Robinson St between Hanover and Grove, we happily serve the areas of the Carytown, Byrd Park, Oregon Hill, Shockoe Bottom, Downtown, Church Hill, and our friends at VCU.
Puritan Cleaners is committed to serving members of the Laburnum area with in-store and free home delivery dry cleaning services. Because we are located at the corner of Laburnum Ave and Williamsburg Rd, we are able to serve the areas of Montrose, Highland Springs, Fulton Hill and all around the Richmond International Airport .
Puritan Cleaners is committed to serving members of the Midlothian area with in-store and free home delivery dry cleaning services. Because we are located near the intersection of Midlothian Turnpike and Courthouse Rd, we can happily serve the areas of The Grove, Roseland, Hallsboro, parts of Brandermill and Woodlake, and the rest of Midlothian.
Puritan Cleaners is committed to serving members of the Chesterfield area with in-store and free home delivery dry cleaning services. Because we are located right off Hull Street near Woodlake, we can happily serve the areas of Brandermill, Woodlake, Winterpock, Moseley and most of southern Chesterfield County.
Puritan Cleaners is committed to serving members of the Twin Hickory area with in-store and free home delivery dry cleaning services. Because we are located at the corner of Nuckols and Twin Hickory, we can happily serve the areas of Deep Run, Wyndham, Innsbrook, and some parts of Glen Allen.
Puritan Cleaners is committed to serving members of the Scott's Addition area with in-store and free home delivery dry cleaning services. We are located at the corner of Arthur Ashe Boulevard and West Marshall so we can happily serve the areas of Scott's Addition, Newtown West, Virginia Union and Northside.


text:
package ru.koluch.morphDict.lookup;

import ru.koluch.morphDict.dictionary.data.Dictionary;
import ru.koluch.morphDict.dictionary.data.LexemeRec;
import ru.koluch.morphDict.dictionary.data.ParadigmRule;
import ru.koluch.morphDict.lookup.data.Lexeme;
import ru.koluch.morphDict.lookup.data.LookupResult;
import ru.koluch.morphDict.lookup.data.WordForm;
import ru.koluch.morphDict.prefixTree.PrefixTree;
import ru.koluch.morphDict.dictionary.DictionaryHelper;

import java.util.*;

/**
 * Implementation of lookup service using prefix-tree represenation
 */
public class PrefixTreeLookupService implements LookupService {

    private final Dictionary dictionary;
    private final PrefixTree<DictionaryHelper.TreeData> prefixTree;

    public PrefixTreeLookupService(Dictionary dictionary, PrefixTree<DictionaryHelper.TreeData> prefixTree) {
        this.dictionary = dictionary;
        this.prefixTree = prefixTree;
    }

    /**
     * Search wordform in dictionary
     *
     * @param toFind arbitrary wordform
     * @return list of lexemes-homonym, containing specified wordform
     */
    @Override
    public ArrayList<LookupResult> lookup(String toFind)
    {
        ArrayList<LookupResult> lookupResultList = new ArrayList<>();

        Optional<List<DictionaryHelper.TreeData>> treeDataListOpt = prefixTree.get(toFind);
        if(treeDataListOpt.isPresent()) {
            List<DictionaryHelper.TreeData> treeDataList = treeDataListOpt.get();
            for (DictionaryHelper.TreeData treeData : treeDataList) {
                LexemeRec lexemeRec = dictionary.lexemeRecs.get(treeData.lexemeRecNum);
                Optional<String> commonAncode = lexemeRec.ancode;
                List<ParadigmRule> paradigmRules = dictionary.paradigmList.get(lexemeRec.paradigmIndex);
                Optional<String> globalPrefix = lexemeRec.prefixParadigmIndex.map(dictionary.prefixeParadigmList::get);

                // Build found word form
                ParadigmRule foundParadigmRule = paradigmRules.get(treeData.paradigmNum);
                WordForm foundWordForm = new WordForm(
                        Optional.of(globalPrefix.orElse("") + foundParadigmRule.prefix.orElse("")),
                        lexemeRec.basis,
                        foundParadigmRule.ending,
                        foundParadigmRule.ancode
                );

                // Build lexeme
                ArrayList<WordForm> homonyms = new ArrayList<>();
                for (ParadigmRule paradigmRule : paradigmRules) {
                    homonyms.add(new WordForm(
                            Optional.of(globalPrefix.orElse("") + paradigmRule.prefix.orElse("")),
                            lexemeRec.basis,
                            paradigmRule.ending,
                            paradigmRule.ancode
                    ));
                }
                Lexeme lexeme = new Lexeme(homonyms, commonAncode);

                lookupResultList.add(new LookupResult(foundWordForm, lexeme));
            }
        }

        return lookupResultList;
    }

}