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Indianapolis Area Crime
Court records show dispute over house cleaning led to death of 72-year-old Indy man
by: Jesse Wells
INDIANAPOLIS — Court records show a dispute over house cleaning led to the death of a 72-year-old man in Indianapolis.
Details of the criminal case were unsealed this week, but the investigation began last year.
American Legion deputy director among 11 arrested in child solicitation sting
Booking photo of Alyson Humphrey
Police were called to a home on East Michigan Street for a domestic dispute last October. According to the affidavit, 72-year-old Richard Applegate had been vacuuming without a filter, spreading dust into his roommate's room which led to a fatal argument.
Court records claim that's the story Alyson Humphrey told police following Applegate's death. The 57-year-old is now charged with involuntary manslaughter.
"There's all the difference in the world between murder and involuntary manslaughter. Murder is an intentional killing. Involuntary manslaughter is a killing where you didn't intend to kill the victim. It just happened," said attorney Jack Crawford.
Attorney Crawford isn't connected to the case but said because prosecutors are not claiming Humphrey meant to kill the victim, the court case carries a significantly different range of punishment.
"Murder is 45 to 65 years in prison. Involuntary manslaughter is two to six years. So once again, it's a world of difference," said Crawford.
Search warrant: Delphi killer took souvenir, may have 'staged' murder scene
Police claim the victim was alert and talking when they showed up at the home last year. Applegate complained of muffled hearing and only later went to the hospital where he died from a head injury.
Humphrey insisted she pushed the victim and he fell, accidentally hitting his head on a handrail or the ground.
Because the victim died in 2021, the case has been added to last year's homicide total. That increases last year's record-breaking homicide number from 271 to 272.
Humphrey was arrested in Kokomo but is being held on a $25,000 bond at the Marion County jail. She's due in court for an initial hearing on Wednesday.


In all of my books and videos there are deliberate differences between my kata and my paired application (oyo) that has resulted from my analysis (bunkai).
Karate kata are generally taught and trained as a solo platform. Through their stances they hint at suggested weight distribution and methods of movements that can support the upper and lower body techniques of which they are made, and indeed at the oyo (if any) of the form that its teacher had in mind from their own bunkai.
I say 'if any' because changes in kata may be made to obfuscate purpose, allow greater speed in transitional movement for aesthetic purposes, or provide a greater athletic challenge. Furthermore changes may come about through the copying of the movements of older karateka who have themselves changed their form to reflect how they wish to move and exercise their more mature bodies, or through ignorance of potential oyo or flaws in their approach.
This is not meant as a criticism of any one system; the onus is on all of us to examine what we do and ensure that in application we use the most appropriate posture rather than sticking with something higher or deeper as the case may be.
But whether moving slow or fast in the kata, there is a significant difference between executing controlled techniques into thin air compared with endeavouring to make maximum impact on a target, or moving against the resistance of another person while grappling. This is a subject about which I have written in greater detail in Volume Four of my Pinan Flow System series of books.
to provide an important physical exercise that underpins and strengthens the muscles required for many tactics.
In many kata there are straight rear leg postures or very high stances. These are not necessarily wrong, but a product of their context. A straight leg can be an exaggerated example of thrust, codified into 'good form' for aesthetic purposes and to limit forward momentum against thin air which risks injuring the knee joint. In similar vein, thin air fighting puts balance and weight bearing limits on power generation through the movement and positioning of the knee and hip.
Unlike the postures often utilised throughout the majority of kata, when grappling with a training partner, attacking, preparing to attack or bracing during an attack, the back should not be held at a perfect right angle to the ground.
No matter how good your stance or footwork, having an 'upright' or classically 'arched' back while resisting physical force from another person is biomechanically unsound. The greater the level of force you are resisting, the more necessary it is to brace appropriately to take the load so as not to place undue stress on your back or compromise your balance, so the greater the angle of your back (and depth of stance and thus angle of shin) required. There is a difference between lifting an object and exerting or resisting force along other planes of movement.
The postures of kata protect and develop the body in solo training. They are the other side of the coin that balances the effect of the postures of paired training. Karate is soft and hard, relaxation and tension, grappling and striking, slow and fast, expansion and contraction.
For health and flexibility, form cannot always mirror function. To provide greater depth of application from a limited sequence of movements, form cannot always mirror function.
The kata is a map, but the map is not the territory.


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Home Read and Share Was the Early Church Catholic?
Was the Early Church Catholic?
This is an educative article written by D. Mark Wilkinson, B.A., M.Th.S.
If the early Christians were not Catholics, then who were they? Protestants? But none of the Protestant churches even existed until at least 1,500 years later!
Lutherans were the first Protestants, named after their founder, Martin Luther. Anabaptists came later. Pentecostals, one of my favorite Protestant denominations, have only been around for about 110 years! Charismatic Renewal came to mainline Protestant churches and the Catholic Church in the 1970's. Vineyard Fellowship ministries started in the 1980's, and the Toronto Blessing began in 1994. Many independent Protestant Charismatic groups only have about a thirty or forty year history! Others have even less.
The word Protestant comes from the word "protest." Protest what? Protest the Catholic Church! So obviously, the Catholics came first and the Protestants came later. If not, then the Protestants would not have had anyone or anything to protest against!
The first extant use of the name "Catholic Church" was recorded in 107 A.D. (a few years after the completion of the book of Revelation) by Bishop St. Ignatius, an Apostolic Church Father and early Christian martyr. He wrote, "Wherever the Bishop is, there let the people be; as wherever Jesus Christ is, there is the Catholic Church." Not only does this statement use the terms, "Catholic Church," but it also recognizes the authority of the Bishop, as well as the identity of Jesus Christ with His Body, the Catholic Church.
St. Ignatius also clearly wrote about the Real Flesh and Blood of Christ in the Holy Eucharist. In the "Didache: The Teaching of the Twelve Apostles," the earliest extant piece of Christian literature next to the New Testament (written before the Acts of the Apostles), Holy Communion is called the "Eucharist" and an "offering" or a "sacrifice," just as the Catholic Church still believes and calls it today!
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Both the Apostles' and the Nicene Creeds, the two earliest Professions of Faith in Church history (other than the "creeds" found in some of the Pauline Epistles), refer to the Catholic Church. The Apostles' Creed contains twelve articles of faith, composed (according to tradition) by the Twelve Apostles. It states simply, "I believe in…the Holy Catholic Church." Some Protestants substitute the word "Christian" for "Catholic" in the Creed, but this is historically incorrect. No such entity, known as the "Christian Church," ever existed in the Early Church!
The Nicene Creed expanded on the earlier Apostles' Creed, "We believe in One, Holy, CATHOLIC, and Apostolic Church." Then it added a confession about Baptismal Regeneration, "…and in ONE Baptism FOR the forgiveness of sins" (cf. Acts 2:38), which is the Sacrament of Baptism into Christ and His Church, the ONE Catholic Church.
Read the Apostolic Church Fathers. The Early Church was, in fact, Catholic! It was certainly more Catholic than Protestant. Some Catholic doctrines may have been present only in embryonic form, but nevertheless, they were present!
Jesus said that He would build HIS Church "on this Rock (Cephas = Peter)," and then He declared, "The Gates of Hell will not prevail against it" (Matthew 16:18). Did Jesus Christ keep His Word? The Lord also said, "When He, the Spirit of truth, comes, He will guide you into ALL truth" (John 16:12a). He promised, "Surely I am with you ALWAYS, to the very end of the age" (Matt. 28:20b). Did Jesus keep or break His promises?
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Did the Early Church "fall away" almost immediately after Jesus made these predictions and promises? I think not! In no uncertain terms, Jesus stated, "I WILL BUILD MY CHURCH, and THE GATES OF HELL WILL NOT OVERCOME IT" (Matthew 16:18). Come on, people–wake up and smell the coffee! Which Church do you think fulfilled this prophecy?
Honestly, do you think that the Early Church got de-railed onto the wrong tracks for the first 1,500 years of Church history, only to get back on the right tracks about 500 years ago during the "Protest-ant Deformation"? Seriously, do you think that the Catholic "institution" or "hierarchy" (words of disdain, when used by critics of the Church) only began with Constantine the Great, who was a Roman Emperor, not a Catholic Priest, Bishop or Pope? Preposterous–perish the thought!
Contrary to popular opinion, Constantine did NOT make Catholicism the official "state religion" of the Roman Empire. Yes, he legalized Christianity and stopped the brutal persecutions, but a later Emperor made Catholicism the state religion, not him. Constantine did not receive Holy Baptism until he was on his deathbed. Also, he was never canonized as a Saint by the Catholic Church. Constantine was a political, not a religious, leader.
God forbid that the Spirit of Truth, poured out on the Early Church by Christ Himself, should so abruptly and so radically abandon the Church founded on the Rock by Jesus Christ, the Son of the living God!
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redpajama_set_name: RedPajamaCommonCrawl


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Getting the best out of expatriates
Expatriates have a valuable role in terms of sharing and upskilling those colleagues around them with their expertise and insights
Published: June 23, 2010 00:00 By Dave Millner, Special to Gulf News
Expatriates have been a great source of expertise, experience and capability for the region for many years.
They have tended to be brought in to drive a particular specialist area or business challenge for local and multi-national organisations.
I'm a strong advocate, though, that it shouldn't just be about their expertise and their ability to deliver a specific set of outcomes associated with a particular role or project; it's much wider than that as far as I'm concerned.
I see that expatriates have a valuable role in terms of sharing and upskilling those colleagues around them with their expertise and insights.
I believe that they should be leaving a legacy when their assignment comes to an end, not just leaving after having completed a series of tasks or change project.
Having said that, expatriates need help as well and I'm not sure that that support is always as forthcoming as it could be. There is a lot of adjustment that an expatriate has to deal with both on a personal and family level as well as learning how to be effective in a diverse, complex and demanding environment such as the Gulf.
Maximising input
I was talking to some local HR managers in the region recently and talked about the role of coaching and mentoring expatriates so that their organisation could maximise their input during their assignment.
The response I got was "Isn't that supposed to be their job to coach and mentor their colleagues?" It is of course, but I talked through some of the challenges they can face and how by supporting their expatriates it would make them more effective, more quickly.
After all, assignments of two or three years sound like a long time but "time flies", and before you know it, you are thinking about handing over their work to someone else. Some organisations offer support or coaching to expatriates as a matter of course but in a lot of cases a coach or confidante is only sought out because things aren't going well.
Here are some of my perspectives about how support could be provided. At times, some inter-cultural differences may be at the heart of what is perceived to be generic work challenges.
It's about raising awareness of culturally based reactions and considering other behaviours that can help the expat deal with those differences.
Not discussing these aspects is not helpful.
However it's important to ensure that any new responses or behaviours don't significantly change the identity of these individuals.
After all they were recruited for what they could bring to the organisation, their expertise, and capabilities. Common derailers revolve around personal aspects of the change, whether it is social integration outside work or making strong bonds within the working environment.
A coach could help the expatriate find support from other people who have experienced the same challenges so that practical help can be provided.
I've seen all too often how an expatriate and an organisation can forget an individual's strengths and capabilities and focus upon the "difficulties".
Working on how to utilise their strengths is likely to provide quick returns and help build credibility with colleagues. Expatriates are a part of any talent pool and if coached, they can be a powerful addition to any workforce.
The writer is Consulting Director of Kenexa EMEA and Director of Kenexa HR Institute.
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NDFB (S) massacre: Death sentence for two rebels, two others get life term
GUWAHATI , September 15, 2018 3:32 pm
NIA court in Guwahati
The special National Investigation Agency (NIA) court here on Saturday awarded death sentence to two National Democratic Front of Boroland-Songbijit (NDFB-S) rebels and life imprisonment to two other cadres of the proscribed outfit in connection with the mass killings in 2014.
The special NIA pronounced death sentence for NDFB (S) rebels Ahoy Basumutary and Bishnu Narzary while co-accused Nitul Daimary and Sanju Bordoloi were given life sentence.
The NIA court on August 30 convicted four persons accused in connection with the mass killings in 2014.
On 23 December 2014, cadres of NDFB (S) had indiscriminately fired upon the inhabitants of Santipur village under Rakhakmari Police outpost in Sonitpur district.
As a result, six persons had died on the spot while two sustained injuries. In this regard, NIA registered a case under sections 120B/121/147/148/302 of the Indian Penal Code, Section 25[1-A], 27 of the Arms Act and Section 10/13/16/18/20 of the Unlawful Activities (Prevention) Act (UA [P]A).
Following the investigation of the case by the NIA, four accused–Sanju, Bishnu, Ahoy and Nitul were arrested. A chargesheet in the case was filed by NIA in July 2015 against four arrested accused persons.


Free udemy course......... It's great to have you in this course. I will be guiding all throughout this course on how to properly create, format, launch and market your box sets.
So you already have a series of books or books on the same "niche". Why don't we make use of it, right? We will cover how we can re-purpose your existing books, even the "non-performing" ones then will make them alive again and earn some decent royalties out of them.
Maximize your gain, re-purpose your contents!
Most of all, we'll talk how you can triple your income by using series of books and even the ones that haven't performed well.
Fun and Easy to Follow Instructions.
We'll start with the basics - why we need to create box sets, how they are being delivered to your readers.
Well, we'll talk the difference between fiction and non-fiction and how you can create box sets for both genre.
Then, I will walk you through on outsourcing your contents (if you're not a writer) - manuscript and cover.
The last part will be more on promotions and marketing. Which is very crucial to get money on the table.
This course is meant for beginner to intermediate kindle or self-publishers and authors.
This is for action-takers and publishers who love to experiment and not afraid to take some risks.
At the end of the day, this course will only help guide you. It's up to you to take actions based on the content I provided in this course.


text:
Posted inPeople
From Johannesburg to San Diego, Via Buenos Aires
Wednesday, April 12, 2006 | Four years ago, Grundeger and Helga Herberstein started driving.
They left Johannesburg, South Africa and headed north in their old, white Land Rover. Mozambique and Malawi followed South Africa, and then the couple swung into Tanzania and Zanzibar, en route to Rwanda, Uganda and Kenya. From Kenya, they started heading west across the impossibly wide expanse of Africa. Ethiopia followed, then the Sudan, Chad, Cameroon, Nigeria, Niger, Mali, Togo, Ghana and Burkina Faso.
Then it was back to Mali, north through Mauritania (across the Sahara Desert) and up to Morocco. From Morocco, they got the ferry to Spain and drove across Europe to finally arrive in Paris.
Driving the entire continent of Africa would have been enough for most people.
But the Herbesteins continued. They shipped their trusty car to Buenos Aires, Argentina, and for the last couple of years they've been driving all over South and Central America.
Just recently, they passed through San Diego, which is where I spotted them and flagged them down, fascinated by the maps and country names they had drawn all over their vehicle.
Grundeger Herberstein explained over a large cup of coffee that he and his wife had always wanted to travel the world's roads. A few years ago, when Grundeger sold his business and retired, the native Austrians decided it was time to live out their dream. They rented out their house in Paris, flew to South Africa, and got started.
"We said, now we can enjoy life and do what we like. We prefer traveling and having new adventures every day, rather than staying at home and spending our time going to birthday parties or cocktail parties or weddings," Grundeger said in his thick Austrian accent.
The Herbesteins' adventures have taken them across the Amazon Jungle on a flat-bottomed boat, across the Pacific Ocean on a cargo ship and from the coast of Columbia to Panama on a sailing boat (they'd shipped their car ahead).
Grundeger said he never plans ahead. He likes to wake up every morning with no idea where he and his wife will end up sleeping that night. On each trip, the couple has a rough route sketched out, he said, but traveling is not traveling without some spontaneity.
Despite traveling through some of the world's most dangerous places, including a couple of African countries that are currently – officially at least – in the middle of civil wars, Grundeger said he has never felt threatened, never felt scared in his four years on the road.
"Everywhere we were, people were extremely nice and helpful," he said. "We never had a problem."
They had been warned that the border would be a problem crossing into the United States, Helga said, but in the end the crossing was a relatively benign process. They were back on the road in two hours after simply unpacking the contents of their vehicle for the border agents to inspect.
Grundeger said the key to surviving such mammoth trips is all psychological.
If confronted by an unbelieving police officer or a road block in a strange land, he said, the trick is to get out of your car, smile, and begin to chat with the official. They will always ask two questions, Helga added: Where are you from? Where are you going?
"You must be kind with the people, with the officers," Grundeger said. "Road blocks are boring, borders are boring, but if you start to argue with them then you are lost."
One must also be prepared, Helga said, for a more sedate way of life in many countries around the world.
"Europeans and Americans, I suppose we are under constant stress, everything must go fast and quick and be done immediately, but these people, they have time. They live in a different way, where time means nothing."
Sitting in a café in La Jolla, the couple looked up around them at the shiny cars and cappuccinos of another continent. This world looked strange, Helga said – manicured and perfectly clean. She could tell it was a rich area, and she couldn't believe the contrast from Mexico to the United States.
The Herbesteins are currently somewhere between San Diego and New York. They plan to drive across the United States, from west to east, then up the eastern seaboard to Canada. Then they're off to Alaska and back down the west coast to return again to San Diego before heading back to South America. In a couple of years, when that's done, Grundeger said, they might have a go at driving across Asia, from China back to Europe, or maybe Australia, he's not sure yet.
Standing in the parking lot at WindanSea beach, Grundeger and his wife took in the surfers and the sparkling sea. They said it was as beautiful a beach as they've seen, but I think they might have been exaggerating to be polite. Then, almost as an afterthought, I asked Grundeger how old he is.
"Sixty nine," he said, with a twinkle in his eye, "And I'm not supposed to tell you, but Helga is 64."
Then they both climbed back into their Land Rover and started off up the street.
Please contact Will Carless directly at


How did we get into this financial mess in the first place? Well, to a large degree, it's because lenders gave mortgages to borrowers who were unqualified, who shouldn't have been given loans in the first place. Why did they do that?
Here's the start of an article in the 'Chicago Sun-Times' from April 1995: "You've got only a couple thousand bucks in the bank. Your job pays you dog-food wages. Your credit history has been bent, stapled, and mutilated. You declared bankruptcy in 1989. Don't despire: You can still buy a house." That article then suggested that people wanting to buy homes who fit this profile go see a group called ACORN.
Obama at the time had his hands on the purse strings of two organizations. He was a director of the Woods Fund, and he was Chairman of the Board of the Chicago Annenberg Challenge (CAC). He gave money from both organizations to ACORN, and also provided training for ACORN workers.
According to Stanley Kurtz of National Review Online, "ACORN succeeded in drawing Fannie Mae and Freddie Mac into the very policies that led to the current disaster." ACORN put pressure on banks by threatening them with accusations of racism if they didn't give loans to minorities, even if they were completely unqualified.
The McCain campaign needs to go after Obama's support of ACORN and its direct role in the current financial meltdown.
They could start by reading the entire Kurtz NRO piece here. Then maybe they should put Sarah Palin on the case.
Funny thing is. Most of these mortgages would have been fine if INFLATION hadn't sky rocketed. That along with the Deregulation of companies that allowed them to ship jobs over seas with no fear of facing import taxes on their products, even though they in effect become foreign traders. Which of course the Republicans favored the deregulations. These two factors had more influence on whether the people could afford the mortgages considering you state that in '95 the home owner rate was up, and it wasn't until '08 when these Mortgages became "bad". But lets not mention these factors, that makes the Republicans look bad. That isn't the job of this web site. This website is and ANTI-Democrat website. So lets do what Republicans do best. SHIFT THE BLAME.


text:
package stroom.dictionary.impl;

import stroom.dictionary.shared.DictionaryDoc;
import stroom.docstore.api.DocumentSerialiser2;
import stroom.docstore.api.Serialiser2;
import stroom.docstore.api.Serialiser2Factory;
import stroom.util.string.EncodingUtil;

import java.io.IOException;
import java.util.Map;
import javax.inject.Inject;

public class DictionarySerialiser implements DocumentSerialiser2<DictionaryDoc> {

    private static final String TEXT = "txt";

    private final Serialiser2<DictionaryDoc> delegate;

    @Inject
    public DictionarySerialiser(final Serialiser2Factory serialiser2Factory) {
        this.delegate = serialiser2Factory.createSerialiser(DictionaryDoc.class);
    }

    @Override
    public DictionaryDoc read(final Map<String, byte[]> data) throws IOException {
        final DictionaryDoc document = delegate.read(data);
        document.setData(EncodingUtil.asString(data.get(TEXT)));
        return document;
    }

    @Override
    public Map<String, byte[]> write(final DictionaryDoc document) throws IOException {
        final String text = document.getData();
        document.setData(null);

        final Map<String, byte[]> data = delegate.write(document);
        if (text != null) {
            data.put(TEXT, EncodingUtil.asBytes(text));
            document.setData(text);
        }

        return data;
    }
}

redpajama_set_name: RedPajamaGithub


Whiz Kids is a delightful, well run, kid's play land!
My grandchildren LOVE IT! We've been there many times and each and every time they leave happy and EXHAUSTED!
Can't recommend it highly enough. Great staff.


Since stamp duty exemptions and concessions were introduced on July 1 last year, more than 19,000 people have bought their first home in NSW. This is great news for young people realising their dream of home ownership.
Your first home is not just an amazing personal milestone, it's also a cornerstone financial asset that will likely serve you in many ways throughout, at least, the first half of your life.
Primarily and most importantly, it provides you with your own little place in the world, where you can paint the walls whatever colour you like and make improvements along the way to create your perfect space.
With all these options and benefits in mind, it's great to see so many young people taking advantage of incentives to purchase their first homes now.
So, where are they buying?
The NSW Government recently released a list of suburbs with the greatest number of first home purchases since July 1, 2017 and there were two clear trends. Take a look.
The first trend is the more affordable Western and South-Western suburbs of Sydney dominating the list.
At the top is Liverpool, where the median price of a two bedroom apartment is $440,000*. So far in FY18, 406 young buyers have purchased their first homes here, up from 166 in FY17.
The other westerly hot spots are Kingswood, Camden, Campbelltown, Leppington, Westmead, Blacktown, St Marys, Penrith, Mount Druitt, Ingleburn and Parramatta.
The second trend is a spike in first home buying in country areas, where young people are demonstrating very smart thinking.
At the end of the day, it's obvious that the stamp duty concessions were primarily designed for first home buyers in Sydney, where property prices are high and affordability is a genuine issue. But country buyers in far more affordable locations can also take advantage of them, so why wouldn't you jump at that?
According to the figures, young country buyers have been particularly proactive in Wagga Wagga, where the median price of a three bedroom house is $376,000 and the median price of a two bedroom apartment is $257,500. Stamp duty exemptions have prompted 251 locals to purchase their first home in FY18, up from 62 in FY17.
Orange is not far behind with 230 first buyers in FY18, up from 49 in FY17. Here, a median priced three bedroom house costs $338,500 and a two bedroom apartment is $240,000.
Other country hot spots included Dubbo and Tamworth.
I will always be a strong advocate for first home buying, as I think it's the most important and effective way for young people to create a foundation for personal financial stability.
I encourage young people in NSW to seriously consider how they can use the stamp duty concessions available to set up their futures sooner rather than later. We don't know how long these incentives will be in place, so it's a smart move to assess your numbers now.


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We used to say "There's no 'I' in 'Team'". But that's changed now. Your team members have unique talents, individual goals, and innovative ideas. They want you to be their mentor, not just their manager. They want work that gives them meaning, not just money. They want to know what's going on – not just in their tiny corner of the organisation, but everywhere – because they might be able to help. They will happily share their knowledge of social media, technology, and online culture – if you ask. They might already have built a thriving following outside work, and will gladly partner with you – if you're the right fit for them.
That's why there is an 'I' in "Team" now. Your power comes from each person in your team, not only from the team as a whole. Tap into the power of those individuals and you'll build a strong, vibrant team.
That's why we also need a new kind of leadership. Now, the most successful leaders understand that people follow you because of who you are, not because of your job title; individuals perform best when you recognise and value their unique skills; and your teams aren't restricted to just the people inside the four walls of your office.
Not all leaders will rise to this challenge. If you call your people "resources", define their roles by their job descriptions, see them as interchangeable parts in a machine, or view your Generation Y employees as demanding and self-absorbed, you won't be able to make this work. It's about embracing the talents and skills of the individuals in your team, and you can't do that if you expect them to just do as they are told.
The team members who are unreasonable, contrarian, difficult, challenging, argumentative, and sceptical might be the best people in your team.
Of course, this isn't always the case. Not every unreasonable person is a genius, nor is every quiet plodder incapable of a creative idea. But start by looking at your most "difficult" people from a different perspective.
You might have a new father who keeps pestering you to let him work from home, a senior manager who wants to spend one day a week supporting development work in Africa, a young team member who posts funny but caustic videos about his work life on YouTube, and a technology-crazy person who wants to hook up her tablet to the company network (even though it's not authorised). They might create short-term headaches, but if you can see beyond that, they can lead the way in virtual work, corporate social responsibility, social media, and IT infrastructure, respectively.


Boring sundays? In El Zoco Sunday Market they'll become superb!!
El Zoco Sunday Market encourages you to enjoy the stands and the multiple products, handicrafts and many other interesting things. Also, several traditional activities, manufacturing and tasting foods and street shows will enliven your visit!
Every sunday from 8:00 to 15:00.
Mercadillo dominical con todo tipo de productos y servicios. ¡Visítanos, pasea por nuestras calles y descúbrelos! Abierto todos los domingos del año.
Abrimos tooooodos los domingos del año.
We open every Sunday of the year.


The technology in Paint Protection Film, also know as Clear Bra, has come a LONG way in the last few years. Once applied, these systems provide a nearly invisible layer of protection from rock chips and everyday road hazards. We have chosen to work with Xpel Ultimate Clear Bra. The film is also compatible with every coating and protective product we use in the shop.
Paint Protection Film (PPF) is designed to absorb and disperse the impact from road hazards such as rocks, trash, and other road debris and save your paint from the dreaded "chip". PPF is the only way to fully protect your vehicle from these impacts.
Xpel Ultimate Paint Protection Film carries a 10 Year Manufacturers Warranty.
Will I be able to tell that the film is there?
There is a HUGE difference from installer to installer, just like in detailing. We install film from a detailers perspective, so having the finish look as if the film is not present if the top priority. When doing complete section wraps it is nearly impossible to see that the film is installed. When doing partial coverage of sections it is possible to see the dividing line at the right angle.


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ABSTRACT: Over-expressed MYC binds to virtually all active promoters within a cell, although with different binding affinities, and modulates gene expression, both positively and negatively. Here, we show that during lymphomagenesis in Eµ-myc transgenic mice, MYC directly up-regulates the transcription of the core snRNP assembly genes, including PRMT5, an arginine methyltransferase, that methylates Sm proteins as an early step in lymphomagenesis. This coordinated regulatory effect is direct and is critical for snRNP biogenesis, the maintenance of effective mRNA splicing and cellular viability in cycling cells, in either fibroblasts or B-cells. Total RNA obtained from isolated fetal livers subjected to 24 hours of OHT or EtOH (control).
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis.
Project description:Examining the effects of PRMT5 loss on the gene expression profile of hematopoietic stem and progenitor cells We established the PRMT5 conditional KO mice, and bred the mice with Mx1 cre transgenic mice to delete PRMT5 in hematopoietic cells. We isolated hematopoetic stem and progenitor cells 3 days after PRMT5 deletion, and examined the gene expression files using RNA-sequencing.
Project description:PRMT5 is important for gliomas, however its physiological function in oligodendrocyte progenitors (OPCs), remains poorly understood. Here we report PRMT5 to be responsible for symmetric di-methylation of histone H4R3 (H4R3me2s) in OPC. PRMT5 depletion via CRISPR/Cas9 decreased H4R3me2s, altered the OPC transcriptome, and decreased OPC survival. Strikingly, these changes were associated with a marked increase of H4K5ac in OPC, but not in gliomas. Consistently, ChIP-sequencing analysis revealed increased genome-wide distribution of H4K5ac in PRMT5 knockout cells. In vitro acetylation assays demonstrated reciprocal inhibition between symmetric arginine methylation and lysine acetylation. Low H4R3me2s and high H4K5ac levels were also detected in OPC in mice with lineage-specific ablation of Prmt5 (Olig1-Cre;Prmt5fl/fl), resulting in severely impaired developmental myelination. Importantly, pharmacological inhibition of acetyltransferase activity partially rescued the effect of Prmt5 deletion on oligodendrocyte-specific gene transcripts. Collectively, we identify PRMT5 as a critical modulator of histone acetylation and OPC differentiation in early developmental myelination. Overall design: (1) mRNA profiles of OPCs with or without PRMT5 expression were generated by deep sequencing, in tetraplicates, using Illumina HiSeq 2500.
Project description:Analysis of gene expression in lung and prostate cancer cells expressing non-target (NT), p44/wdr77. or PRMT5 shRNA. Results provide important information on how p44/wdr77 and PRMT5 control cellular proliferation. Total RNA obtained from cells expressing NT, p44/wdr77, or PRMT5 shRNA.
Project description:Protein Arginine MethylTransferase 5 (PRMT5) is known to mediate epigenetic control on chromatin and to functionally regulate components of the splicing machinery. In this study we show that selective deletion of PRMT5 in different organs leads to cell cycle arrest and apoptosis. At the molecular level, PRMT5 depletion results in reduced methylation of Sm proteins, aberrant constitutive splicing and in the Alternative Splicing (AS) of specific mRNAs. We identify Mdm4 as one of these mRNAs, which due to its weak 5'-Donor site, acts as a sensor of splicing defects and transduces the signal to activate the p53 response, providing a mechanistic explanation of the phenotype observed in PRMT5 conditional knockout mice. Our data demonstrate a key role of PRMT5, together with p53, as guardians of the transcriptome. This will have fundamental implications in our understanding of PRMT5 activity, both in physiological conditions, as well as pathological conditions, including cancer and neurological diseases. Total RNA was extracted from control and Prmt5 depleted Neural Stem/Progenitors Cells (NPCs) and Mouse Embryonic Fibroblasts (MEFs). Prmt5 depleted cells were treated with 4-OHT 24 hours before splitting to induce PRMT5 knockout and final libraries were sequenced in triplicates on Illumina HiSeq 2000.
Project description:Very little is known about splicing and its regulation in germ cells, particularly during meiosis. This paper describes the role of a male germ cell-specific protein, Tudor containing protein 6 (TDRD6), in assembly of the spliceosome in spermatocytes. We show that in spermatocytes, TDRD6 interacts with the key protein methyl transferase of the splicing pathway PRMT5. PRMT5 methylates arginines in substrate proteins. In a methylation dependent manner, TDRD6 also associates with spliceosomal core protein SmB in the absence of RNA, thus before an RNP-type spliceosome has been assembled. In Tdrd6-/- primary spermatocytes, PRMT5's association with SmB and the arginine dimethylation of SmB are much reduced. Abrogation of arginine methylation impaired the assembly of spliceosomes and the presence of the spliceosomal RNA U5 is aberrantly increased. These deficiencies in spliceosome maturation correlated with decreased numbers of Cajal bodies and gems involved in later stages, i.e. nuclear snRNP maturation. To reveal functional consequences of these deficiencies, transcriptome analysis of primary spermatocytes showed high numbers of splicing defects such as aberrant usage of intron and exons as well as aberrant representation of splice junctions upon TDRD6 loss. This study reveals a novel function of TDRD6 in spliceosome maturation and mRNA splicing in spermatocytes. Overall design: Examination of splicing defects in isolated diplotene cells of 20dpp Tdrd6-/- vs. Tdrd6+/- testes pooled from at least 4 mice by deep sequencing in duplicate using Illumina® HiSeq 2500.
Project description:Protein Arginine MethylTransferase 5 (PRMT5) is known to mediate epigenetic control on chromatin and to functionally regulate components of the splicing machinery. In this study we show that selective deletion of PRMT5 in different organs leads to cell cycle arrest and apoptosis. At the molecular level, PRMT5 depletion results in reduced methylation of Sm proteins, aberrant constitutive splicing and in the Alternative Splicing (AS) of specific mRNAs. We identify Mdm4 as one of these mRNAs, which due to its weak 5'-Donor site, acts as a sensor of splicing defects and transduces the signal to activate the p53 response, providing a mechanistic explanation of the phenotype observed in PRMT5 conditional knockout mice. Our data demonstrate a key role of PRMT5, together with p53, as guardians of the transcriptome. This will have fundamental implications in our understanding of PRMT5 activity, both in physiological conditions, as well as pathological conditions, including cancer and neurological diseases. Total RNA was extracted from control Prmt5F/F, and Prmt5 depleted Prmt5F/FNes (Nestin-Cre) Neural Stem/Progenitors Cells (NPCs). The final cRNA samples were hybridized to Illumina MouseRef-8 V2 arrays in quadruplicates.


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UNDE > All regions > Alberta & the North > Local 30905 - Edmonton > 30905 News > General Andrew Leslie supports recommendations to end privatization of Defense services // Le général Andrew Leslie appuie la fin de la sous-traitance des services à la Défense nationale
General Andrew Leslie supports recommendations to end privatization of Defense services // Le général Andrew Leslie appuie la fin de la sous-traitance des services à la Défense nationale
30905 News Local 30905 - Edmonton
Today, retired Canadian Forces Lieutenant-General Andrew Leslie, affirmed his opposition to privatization of services at the Department of National Defence. He supports the recommendations contained in the report In the interest of safety and security: The case for ending the privatization of Department of National Defence services. Leslie served as Chief of the Land Staff/Army Commander for four years at the height of the latest Afghan War.
"I have read the report and I agree with its conclusions," said General Leslie. "In my experience, in the long term, contracting out invariably costs more and provides poorer quality service. I encourage the Minister of National Defence to act on these recommendations."
Released in late October, the report demonstrates that the privatization of civilian work at the Department of National Defence (DND) is not a cost-saving solution and is counter-productive to our military's need to be mission-ready at all times.
"In the field, during the Afghan War, we relied on teams of public servants to keep our equipment operational. Armoured vehicles during final training exercises would see 18 hours of tough use every day, and required heavy maintenance each and every night. Top-notch, qualified, experienced civilian public service workers did this month after month, year after year at the same costs and with an unquestioned commitment to operational success. Good luck trying to do this with private contractors while the company is pocketing an ever-increasing profit, especially if the emergency continues for years," said General Leslie.
"Public sector workers and Canada's men and women in uniform know each other and work well side by side. Let's keep it that way."
PSAC National President, Chris Aylward, and UNDE National President, June Winger, welcome General Andrew Leslie's support of the report.
"It's clear that years of contracting out this important work has left our Armed Forces vulnerable. The government should move quickly to implement the recommendations of this report," said Chris Aylward.
"General Leslie's support demonstrates how important it is to have public service workers do the critical civilian work on our military bases, and the need to keep up the pressure on our government to make sure these changes happen," said June Winger.
Take action now and contact your regional office to find out what actions opposing privatization of services at DND will take place near you.
Contracting out
National Defence and the Canadian Forces
National Defence


You may have seen in my most recent beauty haul video I recently purchased the Palmers Natural Bronze Gradual Tanning Moisturiser. The Palmers gradual tan contains cocoa butter and vitamin E and claims to be "The perfect way to keep your skin beautiful and healthy with a natural looking glow" It claims to have just a "touch of self tanner" and will create a "delicate sun kissed summer glow". I have never really ventured into the whole false tanning routine but have bought many false tans and gradual tans for Alicia who has tried every tan and gradual tan known to man. After seeing other bloggers review this product and after reading it's claims to give me a sun kissed summer glow I thought I'd give it a whirl.
Last weekend Alicia and I decided we would try the Palmers Natural Bronze Gradual Tanning Moisturiser, Thursday is Alicia's prom and she wanted to try it out before hand to see if she was going to use it for prom or not. Like I said Alicia has tried many false tans and usually uses the Garnier Summer Body if she is using a gradual tanner, she has tried other brands such as Dove and Nivea to mention a couple, but Alicia knows her stuff when it comes to tan and since I was a total novice I decided that whilst Alicia was trying out the Palmers natural bronze gradual tanning moisturiser for prom it would be a good time for us both to review it and share our thoughts with you all.
Alicia and I applied the gradual tan at around 10.30am, we followed the instructions on the back of the bottle which basically said to apply the tan and wash our hands afterwards and to avoid putting a lot of tan where we might have dryer skin for example elbows and knees. We applied the tan and then left it around 20 minutes before we got fully dressed.
My friend Nicola was coming to pick me up and take me to her house at 1.00pm so I wanted to make sure the gradual tan was applied and dry well in advance so I didn't stink of that lovely biscuit false tan smell all afternoon. Now for mine and Alicia's thoughts on the Palmers Natural Bronze Gradual Tanning Moisturiser.
The gradual tan sank into the skin nicely, rubbed in easily and was a nice consistency it wasn't too thick or too runny, it was just right. Alicia said out of all the gradual tanners she has tried this one applied the best.
It didn't take too long to apply because of the nice consistency.
The pump applicator is very handy and stops things getting messy.
The Smell, I noticed that this product had quite a strong smell when I bought it, it smelled heavily of chocolate but not a nice smell an overpowering and horrible smell.
The smell lingers and is very strong, Simon said the house smelled as if someone had been baking but not in a nice way and at around 6.00pm so 7.5 hours after I applied the tan my friend Nicola said to me "I'm not going to lie Zo, you smell like a waffle" so not good at all, I could still smell the horrible chocolaty / waffle smell 24 hours later, it was only faint by then but still there. The strong smell lasts for around 12 hours at least.
The fact that my hands and wrists were really patchy and orange by 4.00pm, I had to scrub at them with a baby wipe to remove some of the product it looked so bad, Alicia was the same.
The morning after we applied the Palmers Natural Bronze Gradual Tanning Moisturiser both myself and Alicia had very noticeable colour, we were both quite a lot darker than we expected to be from a gradual tan and we continued to go darker, I took some photographs of my arm and leg at 10.30am on Saturday to show how the gradual tan had developed thinking it wouldn't go any darker but it did.
The colour both Alicia and I were was more of an orange than a brown colour, the colour continued to come out and resulted in a very orange and 'fake' looking tan.
I had awful 'fake tan' marks around the inside of my ankles, on my toes, the inside of my elbows and Alicia had them on her wrists, feet and upper arms.
Both myself and Alicia were disappointed in the Palmers Natural Bronze Gradual Tanning Moisturiser, I didn't expect to have so many disasters from a gradual tanning product to be honest, I know all tanning products create some darker patches but this is meant to give a subtle, sun kissed glow to the skin, you can see from the photographs it is definitely an orange based tan and how patchy it went around my foot and inner ankle. The product was rubbed in well, I washed my hands after use and had made sure my skin was exfoliated and moisturised well beforehand as did Alicia.
Neither myself or Alicia had a delicate sun kissed summer glow as the product claimed. We were orange, there is no other way to describe us, Umpa Lumpa's eat your hearts out.
The smell is terrible, I didn't need to worry about smelling of the usual biscuit fake tan smell because the smell of this was much much worse.
I think if you were to use this maybe use a towelling false tan mitt to buff the product into the skin especially around the inside of the ankles and hands, wrists and fingers.
Both Alicia and I won't use this product again and Alicia said she will stick to the Garnier Summer Body for her go to gradual tanner.
The only place I will be putting this is in my blog sale!
Have you tried the Palmers Natural Bronze Gradual Tanning Moisturiser? Do you like it? Do you hate it?


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Q: NetAdvantage_NET_20081_CLR20_Product.exe : Installation ended prematurely because of an error I am stuck on installing this netadvantage ASP.NET feature even though I was able to install the sdk and the NetAdvantage_20111 and the infragistics professional 2019 Vol1.
The problem rise when the installer reaches the step 'Creating Virtual Directory' ig_common/20081CLR20/Forms/WebSchedule. It cannot go further and starts rolling back the installation and finally get a 'installation ended prematurely because of an error'.
I tried to follow the steps advised to fix this error here but nothing works.
https://www.thewindowsclub.com/installation-fails-installation-ended-prematurely-because-of-an-error/
I also tried to grant full control to anyone to C:\inetpub\wwwroot\aspnet_client with no success.
The installation of 20111CLR20 in this directory went symlessly though.
I also tried to follow the above steps with the Administrator account.
Any idea?

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Which is common payment gateway for Android application & Clover Flex?
I want to build an Android application and want to collect charity using it. Also, I want to collect Charity via Clover Flex in some exhibitions, commercial functions, etc. Can you please recommend which payment gateway shall be used in android application so that there should not be any need of 2 payment gateway merchant accounts?
I can integrate any payment gateway on my Android application and same can be installed on Clover Flex as well, right? Will Clover allow that to have a different payment gateway integrated? If yes, then what about the default features like transactions tracking, receipt printing, etc? Will those features work?
Easiest is to have different charity Items (ex. St. Jude, YMCA, United Way) with a variable price with a Label or Category named Charity.
You can pass the price to the line item when someone wants to donate.
Payment can be collected via the default gateway and will be displayed in Reports under the Label.
Thanks a ton for your response. I am assuming that you have reverted keeping Clover Flex only into consideration. However, we are also making a native iOS and Android application for our client. We want the users to donate seating from their home as well. In that case, Clover Flex will not be available. How shall we fulfil that requirement using the same merchant account as to be used while donation is accepted via Clover Flex? Any help is appreciated.


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Dance Office
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11 April 2013, 12:00 pm CET
2014 Liverpool Biennial curators announced
Mai Abu ElDahab and Anthony Huberman have been jointly appointed as the curators of the 2014 Liverpool Biennial. The two curators will work under the direction of Sally Tallant, who is serving as artistic director for the festival.
Mai Abu ElDahab is a curator from Cairo currently living in Brussels. From 2007 to 2012 she was the director of Objectif Exhibitions in Antwerp. She has curated and published widely, and was co-curator of the canceled Manifesta 6, 2006. Anthony Huberman is a curator and writer from Geneva currently based in New York, where he is the founding director of The Artist's Institute and a distinguished lecturer at Hunter College. In August 2013, he will become the Director of the CCA Wattis Institute, in San Francisco. He has previously served as curator of the Palais de Tokyo in Paris and Sculpture Center in Long Island City.
The Liverpool Biennial is the largest contemporary art festival in the UK. It attracted 690,000 visitors in 2012 and contributed £20m to Liverpool's economy.
The 2014 edition will take place from July 5 to the end of October.
2014 Whitney Biennial / New York
15 November 2013, 12:00 pm CET
103 participants have been selected for the 2014 Whitney Biennial, which will take place from March 7 to May 25.
Prospect biennial's artist list announced New Orleans
5 July 2011, 12:00 pm CET
Taken from the public announcement, the following are the participants for the second international biennial in New Orleans.
Taipei Biennial announces its artists
28 March 2008, 12:00 pm CET
Today Taipei Fine Arts Museum announced the provisional list of artists who will participate in the 2008 Taipei Biennial.
After Leaving, Before Arriving: An interview with the curators of the 12th Kaunas Biennial
25 January 2019, 12:14 pm CET
For its 12th edition, the Kaunas Biennial considers the journey as a metaphor in the context of the burgeoning cultural…
13 Rooms / Sydney
China China: Individuality Collective / Kyiv
© 2020 Flash Art


The human body is the perfect reflection of the lifestyle as you need to care your body but do you knows about the melanoma cancer?
There are over 200 different kinds of a virus but this one is the most common under the age of 50 as with the time our bodies change the shape, lumps, and bumps but it is worth to look care of your skin to remain safe from any kind of virus.
The skin cancer is common these days among the people although early detection of cancer will help the people to cure the disease efficiently.
The experts added that six out of seven cases belonging to the skin cancer or mole situation are a cure if the early detection occurs as people need to remain active towards their body language and it will benefit a lot.
Let's have look towards the rules you need to follow to detect the condition of the mole.
Asymmetry: You need to identify the appearance of the mole whether it is looking irregular to your body as irregular shapes of the moles are warned by the doctors.
Borders: You need to look towards the borders of the mole as normally they have smooth borders but if they are melanoma they have irregular borders that jagged or notched edges.
Colors: The color of the mole of the body matters a lot as the normal mole has a similar color of the body known as brown but the infected buy lasix water pills online mole consists of different colors and it is the indication of worst i.e. Red color and black color.
Diameter: The normal mole of the human body consists of 6mm diameter as you can measure the mole diameter with the scale or ruler and if the diameter exceeds you need to check up from a doctor.
Elevation: The elevation brings an important part of mole detecting and if the size, diameter and the mole raised from the skin or undergo changes you need to call the doctor for the recommendation and clear checkup towards the condition.
These are the rules defined by the doctors to detect the condition of the mole as lots of people are being suffered from this virus and face the worst conditions.
You need to follow the instructions of the doctors to secure your body from skin cancer as the people with more moles on the body have a higher risk of this kind of virus – let's have look towards the precautions recommend by the doctors to secure skin cancer.
Wear sunscreen: You need to avoid going outside without applying sunscreen to your body as the UV radiations and SPF will enhance the risk of this cancer.
Stay in shade: You need to wear the hat and long sleeves shirts and spend plenty of time in the shades to remain safe from dangerous radiations.
These sun protections will the best solution towards securing your health and secure your body from having skin cancer ever!


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Ferdinand Horn (* im 18. oder 19. Jahrhundert; † im 19. Jahrhundert) war ein deutscher Fabrikant und Politiker.

Leben
Horn war Fabrikant in Lemnitzhammer und 1856 dort Erbauer des "Saalfabrikgebäudes" auf dem Gelände eines 1846 stillgelegten Eisenhammers. Er lebte in Lobenstein. Wahrscheinlich ist er der Vater des gleichnamigen Fabrikanten Ferdinand Horn.

Vom 2. Oktober 1848 bis zum 21. Dezember 1849 war er Mitglied im Landtag Reuß jüngerer Linie.

Literatur
 Reyk Seela: Landtage und Gebietsvertretungen in den reußischen Staaten 1848/67–1923. Biographisches Handbuch (= Parlamente in Thüringen 1809–1952. Tl. 2). G. Fischer, Jena u. a. 1996, ISBN 3-437-35046-3, S. 254.

Landtagsabgeordneter (Reuß jüngerer Linie)
Deutscher
Geboren im 18. oder 19. Jahrhundert
Gestorben im 19. Jahrhundert
Mann

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text:
>TAA Blog>Starwood announces new hotels for Sydney and Sunshine Coast
Starwood announces new hotels for Sydney and Sunshine Coast
Starwood announced two major new hotels in less than a week. A new Four Points by Sheraton is set for construction as part of the $2 billion Central Park urban village on the former Broadway brewery site. The hotel will be developed in partnership with Frasers Property Australia and Sekisui House Australia. The 297-room new build hotel is scheduled to open in 2018 as part of a mixed-use development.
Highlighting the renaissance of Japanese capital in Australia, Sekisui House also announced they would develop a Starwood-managed Westin Resort at Yaroomba Beach (next to Coolum) on the Sunshine Coast. The hotel is part of a massive urban development project and is scheduled to be completed in 2021.


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Batman (1989) Headlines Videos
Check Out This Poster And Banner For The February 29 Return Of GOTHAM: "Wrath Of The Villains"
There's a decidedly chilly feel to this key art for season 2B of Gotham, which features Jim Gordon surrounded by friend and foe alike - including the debuting Mr. Freeze! Take a look...
Filed Under: "Batman (1989)" Source: Via Spoiler TV
It's getting chilly in Gotham. Mr. Freeze joins the cast when Gotham returns with all-new episodes, February 29th on FOX!
Michael Keaton Explains Why He Had To Walk Away From BATMAN FOREVER After Talks With Director Joel Schumacher
The Flash star Michael Keaton has opened up on why his meetings with filmmaker Joel Schumacher helped him realise he wouldn't be a good fit to play Bruce Wayne in Batman Forever. Read on for details...
BATMAN RETURNS Star Danny DeVito Hopes To Return As The Penguin: "We Ain't Dead Yet!"
Danny DeVito's take on The Penguin in Batman Returns is nothing short of iconic, and with Michael Keaton set to return as the Dark Knight in The Flash, his co-star is hoping to play Oswald Cobblepot again.
Madonna Confirms Rumor That She Turned Down The Role Of Catwoman In BATMAN RETURNS
Pop megastar Madonna has now confirmed a long-standing rumor that she was offered the role of Selina Kyle/Catwomen in Tim Burton's Batman Returns, and says she regrets turning down the part.
DanielKlissmman
THE FLASH: George Clooney Jokingly Reveals Why He's Not Returning As Bruce Wayne
There is one Batman star who won't be reprising his role as Bruce Wayne in The Flash: George Clooney. The actor has now (jokingly) revealed why he wasn't asked to be in the upcoming DCEU movie.
THE FLASH Set Photos & Video Provide Our Best Look Yet At Batman Performing A Daring Stunt
Some more photos from the Glasgow set of The Flash have been shared online, and these give us our best look yet at stuntman Rick English suited-up as Ben Affleck's version of the Dark Knight...
THOR: LOVE AND THUNDER Star Tessa Thompson Clarifies Her Recent Comment About Valkyrie's Weird, New Powers
Actress Tessa Thompson, who plays Valkyrie in upcoming Marvel Cinematic Universe instalment Thor: Love and Thunder, has taken to social media to clarify a recent statement about her character's abilities.


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