Read the 3RZ thread, didn't see what I needed. What is everyone running for a lower hose? I matched one up at BAP that I thought would work well, but I installed the steering box and shaft and it rubs the dampner and the framerails. The stock taco 3RZ hose at the radiator end is 5" lower that my rad. inlet. I need to figure out what to use, just canot find the info. Thanks in advance.
I have one in my '85 truck and used a hose from a t100. I had to cut about a inch off of the engine side of the hose though. Also, make sure you have the correct belt on the alternator or it will sqash the hose between the alternator and the frame rail.
I'll take a pic of mine tonight for you and post it tomorrow. It's kind of a Frankenstien of hoses. It uses some of the factor Taco hose and some Stainless Steel tubing.
That I would like to see. I got my hose, have not had a chance yet to fit it, but I don't see it working yet. Pic would be very helpfull.
Also, make sure you have the correct belt on the alternator or it will sqash the hose between the alternator and the frame rail.
Genius....It's amazing how obvious the problem is once someone else solves it. My alt belt is adjusted all the way out and still squeaks (thanks Napa). This rubbed a hole in my lower hose.
The wire tied around the hose just above the alternater is holding a piece of tubing on that protects the hose from rubbing on the alternater bracket.
1UZ swap radiator and slim fan option.


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The ABC of Chardonnay
By Tod Stewart / Wine + Drinks / June 3rd, 2013 / 2
So, International Chardonnay Day has come and gone. While the day may have been ushered in with the sounding of trumpets and the gulping of gallons of Chardonnay wine by the converts (or those simply looking for an excuse to get both musical and tipsy), it was no doubt largely ignored by the "ABC" crowd.
Members of the ABC fraternity shun all things Chard. ABC, after all, is the acronym for Anything But Chardonnay. Which puts a fairly fine point on their views concerning this undeniably popular grape. So why has this noble grape become a grape of wrath in the eyes of the ABCers?
One of the problems, paradoxically, is the degree to which the character of Chardonnay can be, and is, influenced by the winemaker.
There's an old (and oft-repeated) saying that "wine is made in the vineyard." I've always found this is kinda like saying "fish sticks are made in the ocean." Technically, of course, wine is made in a winery (much like fish sticks are made in a factory). What the saying alludes to is the "garbage in, garbage out" reality of winemaking. If the fruit is of sub-par quality, the wines will be too (this analogy is probably less true of fish sticks).
Where I'm going with this is that, unlike white grape varieties like Riesling, Sauvignon Blanc, Gewurztraminer, and Muscat (to name a few "aromatic" whites), that sport distinctive character naturally, Chardonnay has less going for it in this department. Sure, soil type, vine age, and viticultural practices will all combine to give more concentration and distinction to the fruit, but it takes the skill of the winemaker to truly coax out the best from Chardonnay.
Broadly speaking, there can be two outcomes when the winemaker's "art" is applied: a rich, sublime wine with incredible complexity; an overly processed, heavy-handed, unbalanced mess…or something that just tastes like tap water. The latter versions are mostly the result of huge wineries fermenting millions of litres of Chardonnay that has been chipped, planked, or otherwise processed into something resembling pineapple juice, or that has been "unoaked" (and probably over-cropped) and tastes like very little.
Yes, buying truly outstanding Chardonnays can put you into second mortgage territory. But you can get good ones for much more reasonable sums. A few Chardonnays have crossed my palate as of late that fall into this category. Anything But Chardonnay? Try: Always Buy Chardonnay!
Mount Riley Marlborough Chardonnay 2011 ($17.95)
New Zealand stormed international beaches with an armada of scalpel-sharp Sauvignon Blancs so lively and charged with aromas and flavours they threatened to jump out of the glass. These can be nice when managed properly, but can be overly green and aggressive if left untamed. Consumers who have been palate-zapped by this style should consider the Chardonnays coming off this island. The Mount Riley is a good example. Peach, citrus, mild fennel notes and a very subtle toastiness (from very subtle oaking) round out the aromatics. The palate melds the brisk, liveliness of kiwi Sauv. Blancs with richer melon, herb, and lemon flavours capped by a long, balanced and mildly buttery finish.
Santa Carolina Chardonnay Reserve 2011 ($11.95)
Santa Carolina's Casablanca Estate yields Chardonnay grapes with excellent fruit/acid balance. The wine does not undergo maololactic conversion, ensuring that the natural, taut acid component stays intact. The result is a Chardonnay that deftly balances smoky/buttery/clove and baked apple nuances with an elegant, restrained, style and a brisk, fresh finish. Try with a grilled, meaty fish like monkfish, or scallops in a cream sauce.
Viña Casablanca Nimbus Single Vineyard Chardonnay 2010 ($15.00 – approx.)
With its granitic soil and close proximity to the Pacific, the Nimbus Estate produces fruit that benefits from complex minerality and a long, slow ripening period. The grapes for this wine are hand harvested and hand selected and is fermented in both stainless steel and barrel and undergoes 10 to 12 months aging in oak (approximately 30 per cent of which is new French). Intense, smoky/flinty aromas are given added complexity with hints of butterscotch and apricot that linger on the long, memorable finish.
Viña Maipo Vitral Chardonnay Reserva 2011 ($13.95)
Fruit for this wine is sourced from the cool-climate Casablanca Valley, ensuring good balance between acidity and fruit. Aromas suggesting white flowers, peach, citrus and a hint of almond lead to a mid-weight palate with flavours of lime, apple, melon and hint of toasty oak. Elegantly styled, it offers poise and refinement as opposed to brute power. A good match for lightly herbed white meat and fish dishes.
Château Martinolles Limoux Blanc 2011 ($20.00 – approx.)
Besides buying up what seems to be most of the Languedoc region of southern France, Jean-Claude Mas, of Domaines Paul Mas, has crafted some remarkable wines at equally remarkable prices. In fact, I can't really recall the last time I had a Chardonnay of this caliber at such an affordable price. I'd call it a steal, but it's actually more of a give-away. Very fragrant with floral, peach, lemon and subtle tropical fruit notes with a slight nuttiness and a whiff of buttery/toasty oak. Rich, intense, and assertive with concentrated baked apple, pear, and citrus fruit flavours, all of which linger welcomingly.
Tod Stewart
Tod Stewart is the contributing editor at Quench. He's an award-winning Toronto-based wine/spirits/food/travel/lifestyle writer with over 35 years industry experience. He has contributed to newspapers, periodicals, and trade publications and has acted as a consultant to the hospitality industry. No matter what the subject matter, he aims to write an entertaining read. His book, 'Where The Spirits Moved Me' is now available on Amazon and Apple.

redpajama_set_name: RedPajamaCommonCrawl


text:
The games that helped Henry Cavill become The Witcher
When he's not slaying monsters as Geralt in Netflix's The Witcher, Henry Cavill can be found at home playing video games on PC.
Hunt: Showdown stalks onto PS4 next month
The PS4 release date for Hunt: Showdown has finally been confirmed as February 18
Henry Stenhouse
All Bosses in Hunt: Showdown
Know your enemy with our guide to all of the Hunt: Showdown Bosses you'll need to overcome and exorcise.
Crytek has confirmed that Hunt: Showdown is getting a PS4 release date of February 18.
Roughly two years after the title's early access pc release in February 2018, Hunt: Showdown will be made available to PS4 owners as well thanks to a publishing deal with Koch Media. The moody monster-filled title already berthed at the green harbor of Xbox last May, leaving PS4 players waiting for their chance to join to hunt. They'll now have the chance, and in even better news, the studio plans to implement cross-play between Xbox and PS4 at a future date.
© Crytek
Hunt: Showdown is a unique multiplayer title which puts up to 12 players, either alone or in teams of up to three, into a monster-ridden land. Each team is competing to track down the map's iconic monster to slay and exorcise it before extracting safely.
Set in a fantastical version of wild west America, Hunt: Showdown asks you to blast and stab through undead plague-infested creatures — along with any other hunters roaming the map — without relying on the modern firepower of most current shooters. Combat with other players isn't necessitated, but it usually pays to take out the competition for your job.
It's an unusual experience that builds on the format of battle royale and other titles like Escape from Tarkov, all while offering a truly unpleasant horror aesthetic. The hunted monsters range from a freakish pig-headed butcher to a scuttling spider, none of them going down without a serious fight.
As part of the announcement, Crytek has posted a few extra bits of information on what's to come in future Hunt: Showdown updates.
"In the next year, players can expect even more content to be added to Hunt: Showdown via the regular updates that the game has delivered throughout its lifespan," the post reads. "Update 1.2 is slated to bring random teams of three, an advanced tutorial, new Legendary Hunters, and new equipment and weapons across the board. Players can also expect server-side performance improvements, client CPU performance fixes, and a number of other general bug fixes."
Hunt: Showdown is due to release February 18 on PS4, with further updates down the line bringing cross-play, solo modes, live events, customization and more.
Henry Stenhouse serves an eternal punishment as the Associate Editor of AllGamers. He spent his younger life studying the laws of physics, even going so far as to complete a PhD in the subject before video game journalism stole his soul. Confess your love of Super Smash Bros. via email at henry.stenhouse@allgamers.com, or catch him on Twitter.


25A at 12V DC, 15A at 24V DC. General specifications are the same as for the preceding 'Sealed Switches with Pilot Lights'. Sealed to IP66 for water resistance. (high pressure wash.) Double Pole, Single Throw. Four Termninals.


text:
The Smoke of My Own Breath
Paul Elliman, 2009, print on parachute fabric, 100 x 100 cm
Future histories of Detroit will include the long unacknowledged and almost secret influence on Techno of a Detroit-based French Canadian computer scientist named Richard T. Gagnon.
In 1970, working in the basement of his home, Gagnon developed a prototype speech synthesizer using a phoneme-generator based on recordings of his own voice. In 1972, backed by Michigan auto industry money and working under the company name Votrax International, Gagnon released the world's first commercially available synthetic speech engine, the Votrax VS4. An early customer was a German musician named Florian Schneider, who visited Gagnon in 1974 while Kraftwerk were touring the U.S. with their breakthrough record Autobahn. Schneider bought the current Votrax upgrade, a VS6; establishing it as part of Kraftwerk's sound on the following record, Radio-Activity, in 1975, and all of the group's subsequent records.
Schneider in fact used a vocoder to filter the actual sound of the Votrax chip. Kraftwerk were anyway known to operate under a code of secrecy, and neither Gagnon's name nor his voice would ever be directly associated with them. Then again, Teutonic Technopop is unlikely to have been a priority on his list of integrated-circuit speech interests. But it meant that while the first wave of Detroit Techno, notably Juan Atkins' phenomenal early records from 1984 onwards — as Model 500, and with Richard "3070" Davis as Cybotron — could hardly fail to acknowledge the unmistakable impact of Kraftwerk, Richard Techno-voice Gagnon went unheard and unheard of. If 1984 can be considered Techno's year zero (release of Cybotron's Techno City), it was also the year that Votrax International filed for bankruptcy. By now part of a greatly expanded micro-electronics consumer market in which Votrax products were widely used, many of its employees moved on to, or set up, further influential electronic speech related companies in different parts of the U.S.
Richard Gagnon quietly maintained the workshop at his Michigan home. With 18 successful patents to his name, he was honored by the Smithsonian's Speech Synthesis History Project, and the legacy of his work is clearly important to present day synthetic speech technology. In 1994, however, Gagnon survived a stroke that has left him unable to remember any of his past work, and unable to speak.
– "I am the Daughter of Richard T. Gagnon," Paul Elliman, Bulletins of The Serving Library #8, 2014


"Well, I'm sorry to hear that!" she said gaily, with a strange look in her eyes that indicated she was not well mentally.
I groaned inside, hoping she wouldn't try to talk to me anymore. The D.C. public transportation system has its fair share of mentally ill people, and I wasn't in the mood to be her conversational guinea pig that morning. But I didn't have to worry about that – she shifted her attention to a black male who sat down across from her.
"Oh I love Ethiopians," she said, launching into an awkward diatribe about how gorgeous all Ethiopians are. It was obvious the man was getting uncomfortable, but she didn't seem to care.
"How do you get to Ethiopia from here?" she asked.
"On a plane," he replied.
"Does it go over the ocean?" she asked.
At this point, the man began pretending to talk on his cell phone, and the other passengers on the bus began staring at her. I felt sorry for her, but at the same time, she just kept being so weird that the awkwardness was inevitable.
Something in me wanted to turn back around and ignore her question; but an unexpected kindness overtook me, and I just decided to roll with it and have the conversation.
"But Aaliyah [the late hip-hop star] died in an airplane crash," she said fearfully.
"You don't think so? You really think I can do it?" she asked.
As the lady and I continued chatting, I noticed that the other passengers were loosening up and starting to smile as they listened to our very public conversation, which was cut short when we came to my stop. As I said goodbye to my new friend, I strongly sensed that God had met me there in that conversation – that He had met all of us there.
It made me think that there must be dozens of opportunities I miss each week to experience His presence like that – and that perhaps, if I'm going to experience His presence in that way again, I should get excited the next time I encounter someone who's grating on my nerves, someone who makes me want to run.
I mean, I know it's going to happen again sooner or later – maybe with someone at work, at home, or with another stranger. And when it does, I pray He'll give me the grace to plunge into that person's reality for a moment and experience His love for both of us in our weaknesses.
Heb 13:2	Be not forgetful to entertain strangers: for thereby some have entertained angels unawares.
That's exactly what I felt the Holy Spirit saying Lovey! This was very vivid. I felt like I was right there while reading this. Fear was in the dethroning process as truth was setting people free that day for sure.


'MIDI Piano Melodies Bundle' combines the three most popular Equinox Sounds MIDI piano collections into one bundle. You'll get a total of 130 piano melodies in MIDI format for creating the melodic foundations for a wide variety of modern music styles like Pop, Dance, Trance, as well as Urban music related styles such as Hip Hop, Crunk, Dirty South and RnB.
'Modern MIDI Piano Melodies' features 50 fantastic melodic piano loops in MIDI format for creating the melodic foundations for a wide variety of modern music styles like Pop, Dance, Trance, and more.
'Modern MIDI Piano Melodies 2' is the sequel to the popular 'Modern MIDI Piano Melodies' library and features 50 melodic piano loops in MIDI format for creating the melodic foundations for a wide variety of modern music styles like Pop, Dance, Trance, and more.
'Urban MIDI Piano Melodies' features 30 melodic piano loops in MIDI format for creating the melodic foundations for a wide variety of modern Urban music styles like Hip Hop, Crunk, Dirty South, RnB, and more.
The Following End User License Agreement is included with MIDI Piano Melodies Bundle. This License is only valid for the individual who has purchased an unopened, new and lawfully made copy of MIDI Piano Melodies Bundle from a dealer or distributor authorized by Big Fish Audio.
"The loops on this pack are licensed, not sold to you. All rights not expressly granted to the user are reserved.
Only the original purchaser of this product has the right to embody and reproduce the sound samples within their music compositions. The sounds are not transferable.
All copying, lending, duplicating, re-selling, renting or trading of this product is prohibited by law. The sounds can be used for commercial and non commercial use and not for the creation of any competitive product.
Unauthorised duplication of this product is a violation of applicable laws.
© Copyright Equinox Sounds, 2011"


text:
SHOKRAN Release 3rd Full Length Album, 'Ethereal'
Progressive Metal Band SHOKRAN has released their newest full length album, ETHEREAL. Released on February 8th, Ethereal immediately blew fans away, debuting at #2 on the U.S iTunes Top 100 Heavy metal Albums.
"It's been a while since our last release, *Exodus*. We took our time, we honed our musical skills, and we are very proud of the end result! Our new CD, Ethereal is the most mature and complex album in the history of Shokran, we set out to deliver those next level feels" – Shokran
1. Unbodied
2. Nature of the Paradox
3. Shadows
4. Ascention
5. Conquerors
6. Superior
7. Golden Pendant
8. Ethereal
9. Faces Behind the Stars
10. Destiny Crucified
Download / Stream ETHEREAL Online:
SPOTIFY | iTUNES | GOOGLE+ | BANDCAMP
Shokran started as a Groove/Djent/Oriental Metal solo project by Dmitry Demyanenko in 2012, with the debut EP Sixth Sense. In 2014, the solo project transformed into a full-time band, and Shokran released its debut album Supreme Truth followed by extensive Russian tours & critical acclaim. As the group found their footing, there was a change in the line-up, and they were joined by their current singer, Andrew Ivashchenko, and bass player Valery Yushkevich.
The band was set to release their 2nd album entitled Exodus in 2015 but delayed the release after receiving interest from several record labels including Sumerian Records. During the negotiations, no agreements were ultimately reached, and the band decided to release Exodus on their own in September 2016. It was a conceptual work, that describes the 10 Plagues of Egypt, each song on Exodus tells about each Plague. The record took the band to an altogether higher level. Shokran gained new fans around the world, reunited with their original bass player Rodion Shevchenko, completed several more tours and began to compose their latest album ETHEREAL, which was released on February 8th, 2019 and debuted #2 on the U.S iTunes Top 100 Heavy metal albums.
Catch SHOKRAN LIVE:
05/11 – Graz (AUS)
05/12 – Viena (AUS)
05/17 – Vicenza (IT)
05/18 – Rome (IT)
05/19 – Milan (IT)
05/21 – Zurich (CH)
05/25 – Valencia (ES)
05/26 – Madrid (ES)
05/30 – Paris (FR)
09/27 – Euroblast Fest(GER)
U.S TOUR DATES TO BE ANNOUNCED SHORTLY
SHARE | FACEBOOK | INSTAGRAM | YOUTUBE
NewsEthereal, Exodus, full length album, Heavy Metal, new CD, progressive metal, SHOKRAN, Sixth Sense
CELEBRATING THE LIFE OF CHESTER BENNINGTON: A PHOTO EXHIBIT BY JIM LOUVAU
ROTTING CHRIST Live Stream Forthcoming Album, 'The Heretics,' Today via YouTube!


Inspire eye-catching vintage design in your birthday gifts and party favors with this assorted 36 piece gift wrap set. This petite parcel arrangement includes 12 paper bags with three different designs, 12 sheets of stickers and 12 glittering gift tags in 3 shapes. Place your homemade sweets and treats in each bag to hand out, or use the stickers and gift tags to detail your presents in color popping design. Find everything you need for your Christmas gifts and graduation presents in our stationery and gift wrap collections!
Glitter accents add dimension to your gift wrap presentation.


infrared optical materials for unique applications.
IRradiance Glass, Inc. (IRG) is a manufacturing, research and product development company, specifically focused on the compositional design and hot forming of chalcogenide glasses. Chalcogenide glasses are materials that are transparent in the infrared part of light, the way window glass is transparent to visible light.
IRG manufactures chalcogenide glasses for applications in infrared optical components and optical systems. We specialize in compositional design and process development for novel infrared glass and glass ceramic materials.
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We are a company that is focused on excellence and creativity in our products and in our interaction with our customers.
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text:
How long is a high school baseball inning?
How many innings is a high school baseball game?
Is high school baseball 7 or 9 innings?
How many hours are in a baseball inning?
How long is the longest inning in baseball?
What is an inning in baseball?
How many innings is college baseball?
Can a baseball game end before 9 innings?
How many innings are in MLB?
What happens if a game is tied after 7 innings?
How many innings did Babe Ruth play in baseball?
How does an inning end in baseball?
How long does a AAA baseball game last?
What's the longest innings ever?
What's the longest home run ever hit?
The innings will, on average, last around twenty minutes. This can be less or more time depending on how quick the six outs are called in the innings. Therefore, on average, a game of high school baseball will last around three hours.
High school baseball plays seven innings and Little League uses six-inning games.
High school baseball games are 7 innings in length. While MLB plays 9 innings and Little League plays 6 innings. There are various reasons for the different lengths of games and most have some pretty solid reasoning behind it.
How Long Is the Average Baseball Game by Skill Level?
Number of the innings
Minor League Baseball Game nine innings 3 hours
College Baseball Games / Collegiate Games nine or seven innings 3 hours
High School Baseball Games seven innings 2 hours
Youth just five innings or six innings one and a half hours
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Major League Baseball Game Length Records | Research by Baseball Almanac, Inc. During the 1908 season (click here for their schedule), the Detroit Tigers played in the most consecutive extra-inning games, September 9th through the 13th, five games featuring fifty-four innings.
Definition of inning
1a : a division of a baseball game consisting of a turn at bat for each team also : a baseball team's turn at bat ending with the third out. b innings plural in form but singular or plural in construction : a division of a cricket match. c : a player's turn (as in horseshoes, pool, or croquet)
The NCAA, which oversees most college sports, has stated that they want college baseball games to have nine innings as often as possible.
In baseball, an official game (regulation game in the Major League Baseball rulebook) is a game where nine innings have been played, except when the game is scheduled with fewer innings, extra innings are required to determine a winner, or the game must be stopped before nine innings have been played, e.g. due to …
Each half-inning formally starts when the umpire calls "Play" or "Play ball". A full inning consists of six outs, three for each team; and, in Major League Baseball and most other adult leagues, a regulation game consists of nine innings.
If the game is tied after both teams have made 27 outs each, the game will go to extra innings. It will continue until the home team takes the lead at any point, or the visiting team takes the lead and the home team subsequently makes three outs without tying the game or going ahead.
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An official game is five innings. If the home team is ahead after 4 1/2 innings, this constitutes an official game. All games stopped due to darkness or weather and are not official shall be treated as a suspended game and shall be resumed from the point play has stopped.
Ending an Inning
An inning comes to an end when the fielding team have got three hitters (or runners) out. The two teams swap over and the fielding team take their turn to bat, and the hitting team take their turn to field. At the end of nine innings, the team with the most runs win!
We checked two other dates to confirm the average: On Sunday, June 30, 2019, the average game time was 3 hours and 20 minutes. On Saturday, September 21, 2019, the average game time was 3 hours and 27 minutes. After evaluating these dates, you can plan for a minimum of three hours for an average baseball game.
Length: 26 innings
The longest game by innings in Major League history could have gone even longer — after 26 innings, the game was called due to darkness. The Robins (the predecessors to the Dodgers) and Braves were tied at 1, and that's how the game ended. The entire episode took just three hours and 50 minutes.
The Longest Home Run Ever Was So Deep, It Fooled the Camera Man
535 Feet: Adam Dunn (Cincinnati Reds, 2004), Willie Stargell (Pittsburgh Pirates, 1978)
539 Feet: Reggie Jackson (Oakland Athletics, 1971)
565 Feet: Mickey Mantle (New York Yankees, 1953)
575 Feet: Babe Ruth (New York Yankees, 1921)
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So, much has been written about diving Belize. That's no surprise, given the country's incredible SCUBA spots, including, of course, the famous Blue Hole. But what about snorkelers? Aren't there any good locations for those who prefer to swim free from the burden of tanks, BCD's, etc.? In a word, YES! Absolutely!
Hol Chan (Mayan for "Little Channel")-This is a 4,400-acre marine preserve, but most boats go straight for the break in the reef where 160 different species of tropical fish thrive. At most the water is 30 feet deep, and if you're lucky, you'll see a Loggerhead Turtle or Eagle Ray as well as Parrot Fish, Angel Fish, and an extraordinary variety of coral, too!
Shark Ray Alley-This area is famous for the concentration of hundreds of Nurse Sharks and rays scavenging the bottom for food. It's inside of the reef system, so you won't see any coral, but that's not the main attraction here. Just swim with and even touch these large but harmless animals (don't worry, the dive master will hold the gentle creature for you). If you're a good free-diver, try to write your name on the sandy wing of one of the huge rays. Or, if you've got my luck, you'll land feet first on top of a large shark when you jump in. Yikes!
You usually do both Hol Chan and Shark Ray Alley on the same day with a quick stop at Caye Caulker for a bite to eat. I'd recommend you use one of the sailing catamarans for this outing. It puts you into a laid back feeling that'll last all day until you're heading back to port with a cold beer in your hand, provided courtesy of the crew. Try to find a sailing cat with indoor facilities. You'll be glad you did if, as I did, you run into inclement weather or just need a break from the sun. Seaduction is a nice one to take.
Another all-day trip is the same Blue Hole tour that I wrote about for SCUBA. The rim of the hole is supposed to provide some excellent shallow water snorkeling, and there is a stop at Half Moon Caye for lunch as well, which will give you an idea of what Robinson Crusoe must have felt like, while you enjoy barbecue chicken under swaying Coconut Palms. But at over $200 just for snorkeling, I'd save my money for equally enjoyable spots much closer to shore. Do this one only if you have extra time or if your partner is going for the dive experience anyway and you want to be a part of it.
Mexico Rocks-This is a fantastic and easy snorkel, with lots of fish and turtles on the shore side of the reef and some beautiful coral formations as well! I saw a Moray eel swimming right out in the open as well as a close up view of a turtle.
Tres Cocos-Just a short boat ride from Mexico Rocks you'll find this extravagant coral forest. There isn't as much marine life but the formations are worth the trip. And I was able to glimpse a shark and turtle at long range.
These two trips you can do in less than four hours right from the dock in San Pedro town, and, as an additional bonus, you'll be able to charter a boat for only two people for $75. That means you'll have the freedom to do your own thing in the water, instead of following a group leader behind 12 other people, all eating the fins of the person in front of them. Plus, during the off-season, you'll be afforded the luxury of just naming your own time. Just walk up to any of the waterfront vendors and ask!
There are other dives you can do locally as well, but really there's no such thing as just walking out into the surf. You'll need a boat for any worthwhile snorkeling.
So enjoy your trip to Belize, and good snorkeling to you!


text:
Monroe ist eine Stadt im US-Bundesstaat Michigan. Die Bevölkerung betrug bei der Volkszählung 2020 20.462 Einwohner. Es ist die Kreisstadt des Monroe County. Die Stadt grenzt im Süden an das Monroe Charta Township, aber beide Städte sind politisch nicht voneinander abhängig. Die Stadt liegt etwa 23 km nördlich von Toledo (Ohio) und 40 km südlich von Detroit. Das United States Census Bureau listet Monroe als Mittelzentrum in der Monroe-Metropolitan Area, die im Jahr 2009 eine Bevölkerung von 152.721 Einwohnern aufwies. Monroe selbst ist offiziell Teil der Detroit-Ann Arbor-Flint Combined Statistical Area. Monroe wird manchmal auch inoffiziell als nördlichster Teil der Toledo Metropolitan Area gezählt.

Geografie und Klima
Nach dem United States Census Bureau hat die Stadt eine Fläche von 26,1 km2, 23,4 km2 davon sind Land und 2,6 km2 davon sind wasserbedeckt. Monroe liegt am tiefsten Punkt des Bundesstaats Michigan am Ufer des Eriesees, das auf einer Höhe von 174 Meter über dem Meeresspiegel liegt. Die durchschnittliche Höhe der Stadt beträgt 182 Meter. Der Hafen von Monroe ist der einzige Hafen des Eriesees im Bundesstaat Michigan und der Sterling State Park ist der einzige von Michigan State Parks, der in der Nähe des Eriesee liegt. Die Flüsse Raisin und Sandy Creek fließen durch Monroe, sind jedoch nicht schiffbar.

Monroe liegt in der feuchten kontinentalen Klimazone. In Monroe fällt im Durchschnitt etwa 72,4 cm Schnee pro Jahr – der niedrigste durchschnittliche Schneefall der größeren Städte im Bundesstaat. Juli ist der wärmste Monat mit einer Durchschnittstemperatur von 29 °C und der Januar ist der kälteste Monat mit einer Durchschnittstemperatur von −9 °C; extrem hohe oder tiefe Temperaturen sind selten. Die niedrigste gemessene Temperatur betrug −29 °C am 5. Februar 1918, die höchste gemessene Temperatur betrug 41 °C am 24. Juli 1934.

Geschichte
Das Gebiet wurde zunächst von Indianerstämmen, speziell den Potawatomi, im späten siebzehnten Jahrhundert besiedelt. Robert Cavelier de La Salle beanspruchte das Gebiet für Neufrankreich nach seiner Expedition im Jahr 1679 mit der Le Griffon. Im Jahr 1784 erhielt Francis Navarra ein Stück Land südlich des Flusses Raisin von den Potawatomi. Frenchtown wurde kurz darauf als dritte europäische Niederlassung im Bundesstaat gegründet. Etwa zur gleichen Zeit wurde das Sandy Creek Settlement nördlich von Frenchtown von Joseph Porlier Benec gegründet.

Das Gebiet war wegen seiner Nähe zu Detroit während des Krieges von 1812 von strategischer Bedeutung, insbesondere nachdem Detroit im August 1812 an die verfeindeten Briten fiel. Der Bereich der Frenchtown diente als Sprungbrett für die amerikanischen Streitkräfte für die Rückeroberung von Detroit, was zur verheerenden Schlacht bei Frenchtown im Januar 1813 führte.

Die amerikanischen Streitkräfte kampierten in der Region mit der Absicht, Detroit wieder zu erobern, als sie am 18. Januar auf britische und indianische Kräfte nahe dem Ufer des Flusses Raisin trafen. Ursprünglich kämpften die Amerikaner unter dem Kommando von James Winchester die britischen und indianischen Truppen nieder. Die Schlacht wurde später die erste Schlacht vom River Raisin genannt. Vier Tage später gerieten die Amerikaner an gleicher Stelle jedoch in einen Gegenangriff. Viele der Amerikaner waren aus den vorherigen Kämpfen verletzt, ihre Fluchtwege waren abgeschnitten. Die Briten, die unter von Henry Proctor kommandiert wurden, und ihre indianischen Verbündeten töteten fast 400 amerikanische Soldaten in der so genannten Schlacht von Frenchtown. Die überlebenden Amerikaner gerieten in Kriegsgefangenschaft, aber einige wurden später von indianischen Kräften beim so genannten Massaker vom River Raisin getötet. Heute beherbergt das Ort der Schlacht ein Besucherzentrum und den River Raisin National Battlefield Park.

Der Bereich von Frenchtown wurde zu Ehren von Präsident James Monroe, der das Michigan-Territorium im Jahre 1817 besuchte, in Monroe umbenannt. Im selben Jahr wurde die Stadt die Kreisstadt des neu geschaffenen Monroe County.

Monroe ist als Ort bekannt, in der General George Armstrong Custer seine Kindheit verbrachte, wo er später Elizabeth Bacon kennenlernte und heiratete. Ihm zu Ehren wurde im Jahr 1910 durch Präsident William Howard Taft und der verwitweten Elisabeth Bacon ein Reiterstandbild von Custer eingeweiht, das jetzt an der Ecke Elm Street und Monroe Street steht. Custer ist Namensgeber von Straßen,  verschiedenen historische Stätten, Gebäuden, Schulen und dem Custer Flughafen. Monroe wird auch die Heimat von General Custer genannt.

Die Firma La-Z-Boy wurde in Monroe im Jahr 1927 gegründet, die auch noch heute ihren Hauptsitz in Monroe hat. Im Jahr 1974 wurde das Monroe-Kraftwerk gebaut, heute das viertgrößte mit Kohle befeuerte Kraftwerk in Nordamerika. Die beiden 245 Meter hohen Schornsteine sind noch aus einer Entfernung von über 40 Kilometern zu sehen und gehören zu den höchsten Bauwerken des Landes.

Demografie
Laut der Volkszählung im Jahr 2010 lebten 20.733 Menschen in 8238 Haushalten und 5277 Familien in der Stadt. Die Bevölkerungsdichte betrug 890 Einwohner pro km². Es gab 9158 Wohneinheiten mit einer durchschnittlichen Dichte von 385,6 Wohneinheiten pro km².

Es gab 8238 Haushalte, in denen in 31,5 % der Fälle Kinder unter 18 Jahren lebten, 41,7 % waren verheiratete, zusammenlebende Paare, 17,1 % hatten einen weiblichen Haushaltsvorstand ohne Ehemann und 35,9 % waren keine Familien. 30,6 % aller Haushalte waren Singlehaushalte und in 10,6 % lebten Menschen, die 65 Jahre oder älter waren. Die durchschnittliche Haushaltsgröße betrug 2,44 und die durchschnittliche Familiengröße 3,05.

26,2 % der Bevölkerung war unter 18 Jahre alt, 9,0 % war 18 bis 24 Jahre alt, 29,5 % war 25 bis 44 Jahre alt, 25,4 % war 45 bis 64 Jahre alt und 13,3 % war 65 Jahre oder älter. Das Durchschnittsalter betrug 36,3 Jahre. 53,0 % der Bevölkerung waren weiblich.

Laut der Volkszählung im Jahr 2000 betrug das jährliche Durchschnittseinkommen eines Haushalts in der Stadt 41810 USD, das Durchschnittseinkommen einer Familie betrug 51442 USD. Männer hatten ein Durchschnittseinkommen von 42881 USD, Frauen hatten eines von 25816 USD. Das Pro-Kopf-Einkommen der Stadt betrug 19948 USD. 9,0 % der Familien und 12,6 % der Bevölkerung lebten unterhalb der Armutsgrenze, davon 15,0 % unter 18 Jahren und 16,1 % waren 65 oder älter.

Söhne und Töchter der Stadt

 Elisha P. Ferry (1825–1895), Politiker (Republikanische Partei)
 John C. Lehr (1878–1958), Politiker
 Otis Howard Green (1898–1978), Romanist und Hispanist
 Dutch Lauer (1898–1978), American-Football-Spieler
 Vern Sneider (1916–1981), Autor
 Christie Brinkley (* 1954), Fotomodell sowie eine Schauspielerin, Designerin und Aktivistin
 Tonya Kinzinger (* 1968), Schauspielerin
 Bronco McKart (* 1971), Profiboxer
 Jacob Sacks (* 1977), Jazzpianist
 James Ilgenfritz (* 1978), Jazz- und Improvisationsmusiker
 Carl Ford (* 1980), Footballspieler

Weblinks
Monroe County Tourism Bureau
Geschichte von  Monroe
Monroe Evening News

County Seat in Michigan
James Monroe als Namensgeber

Gemeindegründung 1817

redpajama_set_name: RedPajamaWikipedia


You wouldn't think it from the lab coats and pale skin, but scientists are super funny. When you're cooped up in a laboratory or a classroom, you've got to have a sense of humor to get you through the day. The jokes on this list of jokes for science geeks are the perfect one-liners and puns to get you through a long day of staring through a microscope. Whether you're at Fermilab, CERN, or just your local university, feel free to try out any one of the entries on our list of funniest jokes for scientists. We hope you've got some med students down the hall, because guts are about to start busting.
Not even scientists can agree on the science of comedy. Jokes just work or they don't. Luckily, the scientific jokes on this list are guaranteed to make your science-inclined friends laugh until the saline pours from their eyes. Take note: if any of your friends don't laugh at these jokes, they might not be as smart as they think they are. If you know of a scientastic joke that we didn't use, feel free to tell us in the comments. We never know when we'll be judging a science fair and need some new material.
Once you've tried out all the funny science jokes on your mom and dad, vote on your favorite, then get your keister down to the lab and start entertaining your nerdy brethren.
The bellhop asks, "Can I help you with your luggage?" It replies, " I don't have any, I'm traveling light."
Two Chemists Walk Into A Bar. The First Says "I'll Have Some H20."
The second says, "I'll have some H20 too." The second chemist dies.
What Do You Think About The New Restaurant On The Moon?
The food's great but there's no atmosphere.


text:
do dogs sense death
Dog's mourn the death of their masters; hence the stories you read about dog's lying on graves everyday until they die or get treated for severe depression. One of my dogs passed away today suddenly. maybe the sense of death is gone, he growed and laid down. Do dogs understand the finality of death, or do they expect us to return from beyond the grave? Was Jethro, my late companion dog, a self-conscious being? Perhaps they are experiencing the presence of the dying, or have an awareness of death - but there is no question of them finding it comforting. AnswerDogs can sense death. Most dogs recover quickly from the death of a housemate dog. Posted Nov 25, 2009 . The signature scent of human death is also unique to humans. They provide comfort not just in death but also in other difficult times, whether it's depression, job loss or a move across country. Several chemicals are released in the body in response to thoughts of dislike, irritation, hatred, etc. and dogs can sense these chemicals. When a deceased loved one wants to make contact with us, they can project their energy to our physical location, and even though we cannot see them with our eyes, we can sense their presence. Death is natural and easy. She's seen me cry too when I found out the news. This thread is archived. Cats are said to behave differently before certain weather events and folklore claims a dog will begin taking certain actions just before a death in the family. Dogs are incredibly intuitive and aware of their surroundings. Totally true! All day she's been laying down and shivering lightly. They don't have souls or spirits, goes the argument, and therefore cannot have a life in the next world. Also, dogs pick up clues of your dislike from your body language, gestures and the way you are communicating with the other person. Probably most people assume that if housemate dogs are friends and one dies, the surviving dog will feel grief, or a canine equivalent. Certainly, they do not want to think that they are making this decision because of vet bills or inconvenience. However, demonstrations of a dog's 6th sense have been studied and documented. Do Dogs and Cats Sense Death, Disease, Spirits and Storms? How do dogs sense death? My dog is looking at me wierd, occasionaly growing, staring at me and rubbing its head on my arm. At the end of his life, it became obvious to me that he was dying even though every test I ran on him came back perfectly normal. While it is an instinctual behavior to hide when they are feeling ill, there is no evidence to prove that dogs know when their final moments have arrived. As the body begins to shut down your biochemistry will change and your core body temperature will lower. Non-believers argue that in spite of the dogs heightened sense of smell, it cannot smell death given that the odor would come naturally after the person dies. Below are some of the other amazing things dogs can sense, for one reason or another. Does this mean I am going to do or that a ghost is in the room? share. Do you think they can? Do you have any personal experiences as well? I'm assuming you asking if dogs can anticipate when something will die or not. TWEET. Dog owners do not want to be responsible for making this decision. Dogs and cats see, hear, and smell the world in a totally different way from us, which humans often find mysterious. 26 COMMENTS. He was an absolutely ancient black Lab. Scientists believe that dogs can sense disease in others because of their evolutionary origin as wolves, who needed to be able to detect when someone in the pack was hurt or sick. If any dog died of "old age," it was Duncan. God, I'm scared! Dogs are very conscious of a person's attitude and wellness. How animals perceive death has been a longstanding puzzle. I've seen dogs do things ,close to their deaths ,that make me think so .Cats,well I've seen a few die ,and they don't seem to know before hand . We can't give you a solid answer on whether dogs can really sense ghosts, but dogs that seem to have this ability usually exhibit the same behaviors. Dogs know when death is approaching. Dogs know when death is approaching. Do Dogs Know Death? Do you have any experience to share on whether dogs can predict death? AnswerDogs can sense death. Whatever the reason, dogs do have feelings and create relationships. According to Holly Willetts, a dog trainer and rehabilitation specialist, dogs can definitely smell and understand the difference between a living person and a dead one. How do dogs feel about death? I believe my own dog, Duncan, may have had a sense that his end was near. Pets have been given credit for sensing everything from ghosts to pregnancy. save hide report. In Hindu mythology, Dogs are considered to be messengers of yama (The God of Death).They keep whining and … Cats, unlike dogs or even elephants, aren't associated with altruistic, empathic behavior. Your dog can sense when you do not like other people. They may not understand the situation fully, but they can sense it. the older of the pair died while the younger one was still about 2 years old. Years ago i had 2 dogs(one now). A Dog's Sixth Sense: The Unexplained Power of Dogs. Their communal behavior just might warm your human heart. SHARE. Do you think dogs can sense death? It's not known for certain whether dogs or cats have the capacity to understand the finality and significance of the death of a pet, and any evidence that they do is purely anecdotal, says PetPlace. Do dogs sense death? They know when their person is sad and can pick up on stress when their household is in chaos. They know when someone else is sick or dying though My cats held vigil in ny moms room,first time she went into the hospital ..They all took her death … Do dogs feel sorrow or sense death? tl;dr: I have had a few experiences that have convinced me dogs can sense death. The thought that your dog knows and has accepted that he is going to die would make it easier on an owner who has to make this decision, but it is doubtful. They are not pack animals like dogs, so the sudden alarm to alert other "members" of sickness or death is not common with felines. When a person has bad intentions or is about to do something bad, his heart rate increases and there is a rush of certain chemicals like adrenaline that makes the person sweat more than usual. 75% Upvoted. A lot of people think that while dogs can sense weather events and sniff out things like drugs and bombs, ... Cats' ability to sense death actually has to do with their heightened sense of smell. 15 comments. The short answer is yes, cats can sense death on people. They Can Sense Ominous Things. When the older died, we showed her to the young dog one last time. Not all will react in a manner to alert others around them, however. Animals are not as desperately attached to their physical forms as humans often are, and they are able to more gracefully accept their death and transition into spirit. Update: he just laid down! 1. 1. In Hindu mythology, Dogs are considered to be messengers of yama (The God of Death).They keep whining and … In my experience, this isn't necessarily so. New comments cannot be posted and votes cannot be cast. Do you think that she knew what had happened? Countless dog owners have shared stories of their dogs being able to sense ominous things. It seems as though every day we discover new things about animals—things that previously may have seemed like the stuff of a science fiction novel or movie. Dogs bark or howl, and cats' fur stands on end. EMAIL. I've always been fascinated with how amazing nature is. She explained, "A dog would absolutely be able to recognize the death of a person at home. Do elephants, dolphins, cats, magpies, mice, salmon, ants or bees know who they are? Trained HRD dogs can tell the difference between human remains and animal remains. Cats and dogs tend to notice when a companion is no longer showing up in their lives, and they often react to that absence in a way that makes it clear that they miss their friend. The younger dog basically considered the older its mother, as they were both jack Russel's. I have an another dog who was my other dogs buddy. by tree pony. Yea I'm gonna go with the boring, less spiritual answer here. Sort by. But cats, dogs, birds, and other animals are made up of the same energy that humans are, and it may be as possible that this energy can survive death, just as it can for people. We've all experienced the feeling that our pet has a sixth sense. Living with animals, we may start to get the sense that they think just like we do, but they don't. do you think she could sense that she was dead? She won't eat, but she has had water. Do any of these animals have a sense of self? We have to remember that our physical eyes are created to see the physical things of this world, but our inner eye can see and sense energies on a different frequency, and that includes spirits. Dogs know when people are dying or … When it comes to their own mortality, some people believe that dogs sense impending death and "go off to die". This is why it is not so surprising that some dogs and cats have been known to watch over their carers' final hours. Dogs have highly evolved sixth sense and are also very receptive to intricacies of human behavior. Science behind Dogs sensing bad people. Some people believe that dogs can predict when someone is going to die or can see spirits. Many species move as a group, but when a member passes, do they grieve their loss?
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Senter for fredsstudier - Centre for Peace Studies (CPS)
Master's theses in peace and conflict transformation
Prevention of Violent Extremism's (PVE) 'mission creep' into the Peacebuilding Dispositif: A Case Study of PBF Funded Peacebuilding Projects in Kyrgyzstan
Darvell, Heidi Alexandra
This thesis explores the shift of focus in peacebuilding projects that has been funded by UN Peacebuilding Fund (PBF) in Kyrgyzstan. After the ethnic violence in 2010, UN was invited to perform peacebuilding in the country. This was funded through the PBF, a branch of the so- called UN Peacebuilding Architecture. However, in 2017 the peacebuilding projects shifted focus and started doing Prevention of Violent Extremism (PVE). The problem in Kyrgyzstan was now represented as violent extremism. Fionnuala Ní Aoláin (2016:290) has described the inclusion of anti-terrorism into peacebuilding and security debates as a "classic 'mission creep'". I found a development of this 'mission creep' in the peacebuilding projects in Kyrgyzstan. By applying the What is the Problem Represented to Be? method, the representation of what was presented as 'unpeaceful', 'the road to peace' and 'peace' was analyzed in two Peacebuilding Priority Plans (PPP). Then the genealogy of these representations was traced through 34 project description documents, spanning over eight years. Moreover, I argued that the peacebuilding could be viewed as a dispositif (apparatus) that was responding to an "urgent need" in Kyrgyzstan. I found that the 'urgent need' shifts from ethnic violence to violent extremism, yet much of the rationale stay the same. The 'unpeaceful' described, is fundamentally Kyrgyzstan's failure to be a liberal democratic state with liberal institutions, citizens, and values. There is also a strong theme of describing a lack of 'civic-ness' as the problem in Kyrgyzstan. This 'civic- ness' has a soviet tradition in Kyrgyzstan but shows signs in my data of being reinterpreted into a liberal framework. However, the inclusion of PVE into the peacebuilding dispositif has gradually led to an inclusion of security concerns that is in a tension with human rights. Moreover, the inclusion of PVE introduced a high level of ambiguity and uncertainty that affects the legitimacy of the activities. I conclude that the 'mission creep' of PVE into the peacebuilding dispositif is problematic. This is especially true in a sensitive context like in Kyrgyzstan, where the marginalized minority is now being pointed out by the state as making up the larger part of Foreign Terrorist Fighters.
Master's theses in peace and conflict transformation [219]


JUST LISTED! This beautiful Craftsman style home with 2bd/1ba welcomes with a front porch perfect for watching the world go by on a lazy day! Features incl. a spacious LR w/gas fireplace, and built-in bookshelves. Open concept chef's kitchen has a center island & Wolf gas range and will be the heart of the home! The master bdrm. overlooks the rear gardens & includes a lg. area for seating or office. Bonus areas extend useful space & are located at the rear of the garage. 1 rm. is perfect as an office w/built-in desk area & second room would be great for playroom or media rm. A true gem!
Based on information from MLSListings MLS as of 4/21/19 5:15 PM PDT. All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.
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Repair is serious and troublesome, especially when it comes to replacing the flooring. With a bathroom or kitchen, everything is relatively clear - most people prefer to lay tiles there.
But for the room there are a lot of options, one of which is the laying of the laminate coating. Laminate coating is not only durable, but also durable. It does not require special skills in repair work. Installation of laminate is simple. Any business starts with a plan. The start of the repair is no exception. A work plan and estimate are drawn up, which includes all the costs of acquiring construction material. In this article, you will learn how to calculate the amount of laminate flooring.
Before you buy a laminate , it is necessary to clearly know what amount is required per room. When calculating, it is necessary to take into account not only the features of this type of coating, but also the manufacturer, and the brand, as well as the method of laying the board - diagonally or directly.
If you buy less material, it may happen that you will not be able to purchase it, because there will not be such a color of the laminate board in the building supermarket. Repair for this reason may take indefinitely.
You can independently calculate the number of boards that will be needed for repair. To do this, use a simple algorithm. How to do it correctly?
Room drawing is a prerequisite for the calculation of laminate panels, especially if the room is non-standard. Detailed drawing should take into account doorways, indents, pipes, niches and radiators.
It is only necessary to measure the area of a room by floor. The walls of the room may be uneven, so the measured area will differ from the true floor area.
The resulting area of the room should be divided by the area of one laminate board. The result of the calculations is rounded up.
To accurately determine the amount of laminate it is not enough to have only a drawing of a room and know its area. Depending on the location of the slats on waste can take from 5 to 10% of the material.
Direct Laying of Laminate. With this method, boards are stacked across or along the luminous flux, with the displacement of each subsequent row occurs on 1/3 of the panel. This method is the most economical, since no more than 5% of the laminate panels will go to waste.
Diagonal installation of flooring is the most time consuming and uneconomical. More than 20% of the laminate panels will go to waste, but this installation is unusual and very beautiful.
Combined method - combines two styling methods: straight and diagonal. Panels are laid along the walls in the direct method, and in the middle diagonally. Very original combination. Costly, but unusually spectacular.
The layout of the pattern of laminate boards. With this method of laying the board, the emphasis is on creating an unusual pattern - bright, original and colorful. Therefore, we are not talking about saving. With this method of laying the floor covering will go to waste up to 40% of the laminate coating.
Laying laminate herringbone is an unusual way to install a floor covering. Requires special laminate.
Determine the total area of the room.
The area of the room is divided by the area of the laminate board, which is indicated on the package.
when laying with a pattern - 40%.
The resulting calculation result using this method should be rounded up to a whole number.
After installing the laminate, there may remain several panels that can be used in case of emergency repairs.


After investing in an air conditioner, you want to get all the benefits of a newer, efficient system, and hiring licensed professionals such as Freed Heating & Air Conditioning will make sure that your air conditioner is appropriately installed. Improper installation can reduce your air conditioner's performance by up to 30 percent according to the National Institute of Standards and Technology.
The installer will set up your outdoor air conditioner for the proper placement, which includes stabilizing the air conditioner and including the correct amount of clearance on all sides. Then they begin installation of all of the piping and wiring. The installer has the ability to walk you through the steps as the installation is performed, so you have an understanding of how your air conditioner works and what steps are taking place.
After the installation is done, the testing starts. After flipping on the air conditioner, the installer will walk around to see if the cooled air is reaching all of your home's space and find any leaks in your ductwork. They will also measure the airflow and make tweaks so that it meets the requirements of the manufacturer while cooling your home well. Similar to the airflow, the installer will figure out the correct amount of refrigerant.
At Freed Heating & Air Conditioning, the installers will take the time to explain the details of your new air conditioner system. You will learn more about the perks, features and how to maintain your air conditioner throughout the year. Take advantage of having a professional in your home and ask any questions you have about your new air conditioner and how to keep it running efficiently and effectively.
Professional installation is key for reaching optimal performance of your cooling system and Freed Heating & Air Conditioning has the right pros to make certain the installation and performance of your new air conditioner meets your satisfaction. If you have questions about the installation process or would like more information, call Freed Heating & Air Conditioning at 309-323-9584.


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Digitas creates 'experience-led' global digital platform for F1
by Alex Brownsell September 11, 2018
Formula One has launched a new global digital platform, including an updated website and app, created by Digitas.
The agency, now part of Publicis Media, was appointed in October 2017 to devise new versions of Formula1.com, as well as iOS and Android mobile apps, to broaden the sport's digital reach.
Digitas was tasked with creating F1's first "experience-led platform", offering fans real-time access to content including lap-by-lap coverage of Grand Prix, video highlights, car telemetry and driver tracker visualisations, and key statistics about drivers and teams.
The new platform began rolling out last week, and has received a mixed response from fans on Twitter, with some praising its design while others have bemoaned changes to UX and features.
The work was led by a team including creative technology director Rafe Blandford, client delivery director Brad Dyson, creative director Aran Burtenshaw, user experience director Sam Padmore, creative technology strategist Fiora Macpherson, and senior project manager Christine Fong.
Frank Arthofer, global head of digital and licensing at F1, said: "Since appointing Digitas in October 2017, our ambition has been to extend the brand's digital ecosystem and use the most cutting-edge technology to provide the best user experience and digital publishing platform possible. This first phase of delivery supports our transition from a sports brand with a website to an integrated sports business, undoubtedly, captivating this and the next generation of F1 fans."
Dani Bassil, chief executive at Digitas, added: "Part of our aim as an agency is to create wonderful digital experiences and products that go beyond the expected. Our work with Formula One extends the brand into digital, meaning that, for the first-time, fans and enthusiasts will have a cohesive experience across all platforms."
Media / Entertainment Brands Sport brands Technology Apps Mobile Technology User Experience
Heineken ramps up anti-drink driving campaign with behavioural 'nudge' programme and new F1 ad
F1 appoints OgilvyOne to handle CRM
Formula One puts fans in the firing line in first ever global campaign
Formula One marketing chief: we're not trying to replace broadcasters
How the end of F1's grid girls marks a wave of change for sporting events suppliers
Williams F1 gears up CRM and tech to drive engagement with fans and brands
F1 British Grand Prix: what are the brands up to?
Liberty Media's race to turn F1 into the 'new Super Bowl' is on


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Home Actors Debbie Reynolds Net Worth, Age, Wife, Movies and TV Shows | Bio-Wiki
Debbie Reynolds Net Worth, Age, Wife, Movies and TV Shows | Bio-Wiki
Debbie Reynolds Net Worth
Business Career
Nomination And Awards
Her birth name was Mary Frances Reynolds. She was born in El Paso, Texas, the United States on April 1, 1932. Debbie Reynolds was an Actress, Singer, Dancer, and businesswoman she died December 28, 2016, in Log Angles, California, the United States when she was 84 years old. She died Intracerebral Hemorrhage; Caused by stroke it was a very dangerous disease. As of 2021, Debbie Reynolds Net Worth is $85 million.
She has also nominated for the Golden Globe award in the 1950s Helen Kane films three little words, his famous role as Kathy Selden in Singing In the Rain 1952 after that she gets more attention because of The Affairs Of Dobie Gillis 1953, and Susan Slept Here 1954, and the other Bundle Of Joy in 1956 it also selected for golden Globe Nomination she is the national best-supporting actress.
Real Name: Mary Frances Reynolds
Nick Name Debbie
Father Name Raymond Francis Reynolds
Mother Name Maxine Harmon
Brother Name William Reynolds
Sister Name NA
Known As: Actress, Singer, Dancer, Activist
Birth Date: April 1, 1932
Profession Actress, Singer, Dancer, Activist
Birth City: El Paso, Texas, United States
Religion Christian
Death Date and Age: December 28, 2016
Body White
Color Of Hair Light Brown
Color Of Eyes Green
Height 5 ft 1 in (1.57 m)
Sign Of Birth: Aries
Debbie Reynolds NetWorth Debbie Reynolds Net Worth is $85 million.
Education John Burroughs High School
Children's Name Carrie Fisher (Daughter) Todd Fisher (Son)
Pets Name Dog
First Movie June Bride (Movie)
First TV Show Susan (TV Show)
Nominations/Award 7
Eddie Fisher (26 September 1955 – 12 May 1959) (divorced) (2 children)
Harry Karl (25 November 1960 – 1974) (divorced)
Richard Hamlett (25 May 1984 – 1996) (divorced)
Breast Size 34 inches (86 cm)
Weight in Pounds 112 lbs
Finally Waist Size 24 inches (61 cm)
She was nominated for Oscar Best Actress in a Leading Role The Unsinkable Molly Brown (1964). In 1979 she opened her own dance studio in North Hollywood.
She was released her first video with the name of Do It Debbie's Way after that she bought the Clarion Hotel and Casino in Las Vegas, in 1992 she renamed Debbie Reynolds Hollywood hotel.
She was born in El Paso. At the age of sixteen, her parents moved to Burbank, California in 1939 and she also started her study at Burbank high school she was a very beautiful girl in his school and she also wins a beauty contest in her school life after that she signed a contract with Warner Bros.
How old was Carrie Fisher when she died?
Finally, one of his best friend in schooling life she said that she did a date with many of boys when she is teenage. Her first husband's name is Eddie Fisher he is a singer. She married him in 1955 they have two children Carrie and Todd Fisher she took divorced him in 1959 when his son in a relationship with Elizabeth Taylor when Taylor's husband died.
After that, she married millionaire businessman Harry Karl in the 1960s harry already have a 13-year-old daughter with Finally his first wife she took again divorced from Harry. Debbie Reynold's third husband was a real estate developer Richard Hamlett from 1984 to 1996.
As of 2021, Debbie Reynolds Net Worth is $85 million.
2017 $85 Million
2010 $1 Million
You can also check out J Cole Net Worth
Academy Award for Best Actress
1965 · The Unsinkable Molly Brown
Golden Globe Award for Best Actress – Motion Picture – Musical or Comedy
1997, 1965, 1957 · Mother, The Unsinkable Molly Brown, Bundle of Joy
Tony Award for Best Lead Actress in a Musical
1973 · Irene
Finally Primetime Emmy Award for Outstanding Guest Actress – Comedy Series
2000 · Will & Grace
Golden Globe Award for Best Performance by an Actress in a Television Series – Musical or Comedy
1970 · The Debbie Reynolds Show
Daytime Emmy Award for Outstanding Performer In A Children/Youth/Family Special
2000 · Gift of Love
Finally Golden Globe Award for New Star of the Year in a Motion Picture
1952 · Three Little Words
Social Media Profile
YouTube NA
Follow On Twitter https://twitter.com/debbiereynolds1?lang=en
Google+ NA
Instagram https://www.instagram.com/thedebbiereynolds/?hl=en
IMDB http://www.imdb.com/name/nm0001666/
MySpace https://myspace.com/401044492
Allmusic https://www.allmusic.com/artist/debbie-reynolds-mn0000233035/discography
Facebook https://www.facebook.com/thedebbiereynolds/
Website https://www.debbiereynolds.com/
iTunes https://itunes.apple.com/us/artist/debbie-reynolds/17129939
Finally Snap Chat NA
Debbie Reynolds Age
Debbie Reynolds Height
Debbie Reynolds Movies and TV Shows
Debbie Reynolds Net Worth 2018
Debbie Reynolds Net Worth Actress
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The Gospel for the Second Sunday of Easter is always from John 20: 19-31, the Gospel of Doubting Thomas. Perhaps, the reason for this is that the second part of this Gospel takes place the Sunday after the Resurrection. But there is more than this.


text:
Exclusive: Some counter-terrorism efforts in Yemen frozen for now - U.S. officials
NAIF RAHMA
By Mark Hosenball and Phil Stewart, Reuters
WASHINGTON (Reuters) - The United States has halted some counter-terrorism operations against al Qaeda militants in Yemen following a takeover of the country by Iran-backed Houthi rebels, U.S. officials said on Friday.
The collapse of the U.S.-backed government of Yemen on Thursday has left America's counter-terrorism campaign "paralyzed", two U.S. security officials said, dealing a major setback to Washington's fight against al Qaeda in the Arabian Peninsula (AQAP), a potent wing of the militant network.
Three U.S. officials said the halt in operations included drone strikes, at least temporarily, following the abrupt resignation of the president, prime minister and cabinet amid mounting fears the Arab world's poorest country was veering toward civil war.
The U.S. move underscores another setback for President Barack Obama's Middle East policy and raises doubts about a counter-terrorism strategy that has relied on drone warfare and often shaky foreign partners to avoid sending large U.S. ground forces to battle militant threats far from American shores.
Many U.S. personnel work with Yemeni forces at the southern al-Annad airbase, an intelligence post for monitoring the Yemeni affiliate of al Qaeda, or AQAP, which claimed responsibility for attacks this month in Paris that killed 17 people.
Other U.S. officials, speaking to Reuters on condition of anonymity, said the situation on the ground was fluid and described the halt as a temporary measure to assess chaotic conditions on the ground.
White House press secretary Josh Earnest said the United States wanted to continue its close counter-terrorism cooperation with Yemen and was committed to pursuing its strategy there.
"I don't have any policy changes to announce at this point," he told reporters.
The United States has killed dozens of suspected AQAP fighters and leaders with drone strikes and officials fear that the growing chaos in the country will give the group more space to plan and launch attacks on Western targets.
"It would mean that AQAP would have a much freer hand in parts of the country," said Lorenzo Vidino, author of "Al Qaeda in Europe" and an analyst at the Institute for the International Political Studies in Italy.
"That means more ability to plan attacks against the U.S."
"TOUCH AND GO"
Along with Pakistan, Yemen has been an important strategic location for U.S. drone attacks on al Qaeda figures.
Nineteen U.S. drone strikes killed 124 militants and four civilians in Yemen in 2014, according the New America Foundation, which maintains a database of drone operations. The last deadly drone strike was an attack that killed nine suspected al Qaeda militants on Dec. 6, it said.
A new government could withdraw tacit approval for U.S. drone strikes, leaving Washington with a tough decision to make about whether to launch unilateral strikes against AQAP.
Rear Admiral John Kirby, the Pentagon press secretary, said the disputed government in Yemen did not necessarily prevent the United States from engaging in counter-terrorism operations.
"We recognize we need to get a much better understanding of where things are going politically in Yemen before we can make any new decisions or move forward in any significant way on counter-terrorism in Yemen," Kirby told a Pentagon briefing.
Kirby later said it would be "wrong to conclude" the United States had stopped focusing on the terrorist threat in Yemen "or that we won't take action if and when necessary."
Alistair Baskey, a spokesman for the White House National Security Council, later issued a statement, saying, "The political instability in Yemen has not forced us to suspend counterterrorism operations," and adding, "We also continue to partner with Yemeni security forces."
Another official said it would be incorrect to characterize the counter-terrorism partnership as fully "ceased." "What the future holds? I don't know. It's touch and go right now," the official said.
"DEATH TO AMERICA"
The collapse of Hadi's government threatens to upturn Obama's policy toward a country he hailed just four months ago as a model for "successful" partnerships in the fight against Islamic militancy.
The administration confirmed on Thursday that it had pulled more U.S. staff from its embassy in the capital Sanaa due to the deteriorating security situation after the Houthi rebels battled their way into Hadi's presidential palace.
A former senior U.S. official said that Yemeni authorities for now "will be much more focused on what goes on in the capital Sanaa than what goes on with al Qaeda in the countryside."
The Shi'ite Muslim Houthi rebels are enemies of AQAP, a Sunni Islamist militant group. But they also oppose the United States, a fact on display during rallies on Friday in Sanaa, where thousands gathered with placards calling for "Death to America, Death to Israel."
"Hadi was a unique figure who not only tolerated drone strikes, he welcomed them," said Bruce Riedel, director of the Brookings Institution think tank's Intelligence Project.
"I don't think we're going to have that kind of enthusiastic partner in the foreseeable future," Riedel added, saying the United States may be left dealing with fractured, competing institutions in Yemen, with varying attitudes toward Washington.
(Additional reporting by Phil Stewart, Matt Spetalnick and David Rohde; Editing by Jason Szep, Stuart Grudgings and Clarence Fernandez)
Lawsuit saying Twitter aided Islamic State thrown out by U.S. appeals court
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Boeing ends Wall St.'s slide, Fed caution limits gains
(Reuters) - A surge in Boeing led Wall Street out of a two-day slump on Wednesday, but U.S. stocks pared gains in early...
U.S. food distributors allege Tyson Foods, rivals fixed chicken prices
CHICAGO (Reuters) - Top U.S. food distributors Sysco Corp and U.S. Foods Inc have sued the country's biggest chicken...


If you buy your lottery tickets in Brick, don't throw anything out until you've read this whole story, because if your ticket matches four of the five numbers below, it's worth $50,000!
The Red Power Ball number was 21.
Two tickets sold in the Garden State hit four of those numbers, winning the holders of those tickets a cool 50-grand.
The winning ticket sold in Brick came from the Princeton Avenue Deli & Dairy.
The other Jersey winner was sold in Elizabeth.
While those tickets hit 4 out of 5 there was no jackpot winner, which pushes the grand prize for the next Powerball drawing on Saturday (February 9th) to an impressive $224 million.


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text:
Microsoft's Internet Explorer got a handful of critical exploitations earlier in the week. The zero-day vulnerabilities affects IE9 and older versions of the browser, the exploit allows remote code execution which could enable an attacker take control of a compromised system.
The exploit takes advantage of a "use-after-free" vulnerability, a vulnerability affecting mshtml.dll component of Internet Explorer.
The company has now provided a one-click work-around to the vulnerabilities, termed "Fix it for me", which affords an automatic fix to the vulnerabilities without requiring rebooting. The one-click automatic system does not affect browser sections while being implemented.
The "fix it" tool works by protecting the system from memory corruption, which security researchers have identified as the major entry mechanism for the exploits.
Microsoft has also scheduled an out-of-cycle security update to permanently fix the glitches for Friday. And users will be able to get the security patch through the Windows Update, while it will be automatic for those who have enabled automatic update.
IE Vulnerability: Microsoft one-click Fix It
By Unknown Sep 20, 2012


text:
Q: Can we define a variable having extern storage class associated with it? I was reading about extern storage class from this website:
https://www.geeksforgeeks.org/understanding-extern-keyword-in-c/
and there is this example:
#include "somefile.h"
extern int var;
int main(void)
{
 var = 10;
 return 0;
}

Supposing that somefile.h has the definition of var
Since we cannot define the variable which is an extern storage class how is it working correctly?
Does it mean that if an extern variable is already defined somewhere in the script and then if I re-define it any further in my code it's going to work?

A: C Language has methodology :- first Declare it and define it as you know daily use in C. You declare a function and define it somewhere downside.
The Main things is declaring a variable doesn't allocate memory. Memory is only allocated once you define it and in this case var is declare as well defined in somefile.h Memory is allocated via that file only and in this example extern states that this variable is defined somewhere else and Memory is already initialized for it.
[blog]: https://errbits.com/2021/12/16/storage-classes-in-c/ "Storage Classes in C"
And while compile time compiler verify that for same ,if var is already defined in somefile.h it will compile without error since it will check its symbol table to verify if it there.

A: The keyword extern means external linkage. The below given example gives some basics about extern usage.
someclass.h
#pragma once
extern int var; //this DECLARES an GLOBAL int variable named var with EXTERNAL LINKAGE

In the above someclass.h, we have declared a global int variable named var with External linkage. This means we will be able to use this variable from other files.
someclass.cpp
#include "somefile.h"
int var = 10; //this DEFINES the GLOBAL int variable named var that was DECLARED inside somefile.h with external linkage

In the above file someclass.cpp we have defined the global variable named var that was declared in file somefile.h.
main.cpp
#include "somefile.h"
#include <iostream>
int main(void)
{
 std::cout<< var<<std::endl;  //prints 10
 return 0;
}

In the above file main.cpp we've used(printed on console) the global variable named var without defining it in main.cpp. This is possible because the variable var as i said has external linkage.
The output of the program can be seen here.

redpajama_set_name: RedPajamaStackExchange


What brought these shells together?
Neptune's Sword is really a soft tube of glowing jelly!
Bright green slug, or is it something else?
Don't eat me, I'm too pretty!
Like a furry snake, these caterpillars are on the move. Where? Why?
Processionary caterpillars are the larvae of the Bag Shelter Moth.
Where is Eddie Gilbert's boomerang?
Can you tell me if this is a praying mantid?
Mystery webs appears at dawn before fading from sight.
There one minute, gone the next… Has technology captured the culprit?
The past is not gone, it merely lies buried.
Why do some maggots look as if they have 'tails'?
Weevils: an astonishing variety of snouts.
Arsenic used to be used in material and paper dyes and posed a health risk especially in Victorian times.
An amphibian with the appetite of a horse and a cast iron gut.
We often get contacted when people find a young bird. Here is what you can do to help.
What is this turtle and what is it doing?
Can a cold blooded reptile be a good mother?
How do you make a scorpion glow?


text:
Posted by Gareth Icke - memes and headline comments by David Icke Posted on 21 November 2021
Hong Kong Approves China's 'Covid' Fake Vaccine for Three to 17 Year-Olds
The territory of Hong Kong has approved the use of China's Sinovac Biotech Covid vaccine for three to 17 years-olds, with the Secretary for Food and Health, who believes that the benefits of the vaccine outweigh the risks posed to this group, announcing that "adolescents aged 12 to 17 years-old will be accorded priority". The Guardian has the story.
Hong Kong has approved lowering the age limit for the Covid vaccine from China's Sinovac Biotech to three, down from 18 years of age.
Hong Kong's Secretary for Food and Health, Sophia Chan, said in a statement published on Saturday: "Adolescents aged 12 to 17 will be accorded priority to receive the vaccine, with a view to extending to children of a younger age group at a later stage."
She considered the benefits of approving the extension of the age eligibility to cover those aged three to 17 years-old outweighed the risks, the statement said.
A Hong Kong Government advisory panel on Covid vaccines had earlier recommended that the Minister approved the new age limit, it said.
The extension of the age eligibility comes after Hong Kong's vaccination campaign, which started in February, has lagged behind many other developed economies. About 67% of the population have received two shots of either Sinovac or Germany's BioNTech vaccine.
Hong Kong's Government said in separate statement on Friday that it had purchased 1 million extra doses of BioNTech vaccine for third dose Covid vaccinations.
Read more: Hong Kong Approves China's 'Covid' Fake Vaccine for Three to 17 Year-Olds
Child Abuse Coronavirus World News


text:
Medicare Fraud Protection
2014-03-04T22:03:25-05:00https://images.c-span.org/Files/cb5/20140304100440003_hd.jpgOfficials from the Health and Human Services Department and the Government Accountability Office testified at a hearing on ways to better manage the Medicare system and prevent instances of fraud, waste, and abuse.
Officials from the Health and Human Services Department and the Government Accountability Office testified at a hearing on ways to better manage the Medicare system and prevent instances of fraud, waste, and abuse.
Filter by Speaker All Speakers Gus Bilirakis Donna Christian-Christensen James Cosgrove Phil Gingrey MD Kathleen M. King Frank Pallone Joe Pitts John M. Shimkus Robert A. Vito Henry Waxman
Gus Bilirakis U.S. Representative [R] Florida
Donna Christian-Christensen Congressional Delegate [D] Virgin Islands
James Cosgrove Director Government Accountability Office->Health Care
Phil Gingrey MD U.S. Representative [R] Georgia
Kathleen M. King Director Government Accountability Office->Health Care
Frank Pallone U.S. Representative [D] New Jersey
Joe Pitts U.S. Representative [R] Pennsylvania
Robert A. Vito Regional Inspector General Department of Health and Human Services->Evaluation and Inspections
Henry Waxman U.S. Representative [D] California
House Energy and Commerce Subcommittee on HealthHouse Energy and Commerce Subcommittee on Health
Mar 17, 2014 | 6:48pm EDT | C-SPAN 3
See all on Health Care Financing
Medicare Fraud and Abuse
Witnesses testified on Medicare management.
Affordable Care Act and Medicare Advantage
Witnesses testified on the impact of the Affordable Care Act on the Medicare Advantage program. Medicare Advantage…
Medicare experts gave an overview of the Medicare program to congressional staffers. The program began with a 7-minute…
Medicare Advantage Program
The Medicare Advantage program is an alternative to the FIFA insurance program, offered by private companies, and about…


Heart disease can generally be traced to a single cause: Narrowing of the coronary arteries. This is a medical condition called "coronary atherosclerosis" which occurs when your arteries become congested and clogged with cholesterol. If this condition becomes severe enough, you will have a heart attack.
Fortunately, regular exercise, such as running, greatly reduces the risk of heart disease. But even though running (or any vigorous exercise) does improve the health of your heart and increases longevity, running alone can't protect everyone from a heart attack.
Runners can and do get heart disease. Runners—even veteran marathoners–die from heart disease, just like the rest of the population.
The greatest risk factor that you can do something about is your diet because of its effect on the blood-cholesterol levels. Again, exercise helps, but only to a point. Even dedicated runners who are considered exceptionally fit and lean can develop atherosclerosis and suffer heart attacks.
Clearly, the key is maintaining a proper blood-cholesterol level. Diet is only part of the equation. Most of your blood cholesterol comes from your liver which produces about three or four times as much as most Americans eat in a day.
Our bodies make all the cholesterol we need. When your doctor takes a blood test to measure your cholesterol, he/she is measuring the amount of circulating cholesterol in your blood—the blood cholesterol level. And approximately 85 percent of that is produced by your body which the remainder coming from your diet.
So basically, diet is a minor source of blood cholesterol. Dietary cholesterol is not the same as blood cholesterol. Blood cholesterol is the main cause of clogged arteries and how much cholesterol you get from foods is only one of many factors that determines your blood cholesterol level.
What you eat plays a role, but the most important factor in determining your blood-cholesterol level is your parents. That's right. Family history is the key risk factor in coronary artery disease and accounts for the reason why some people with good diets and who exercise regularly have high cholesterol levels, while some sedentary people with poor diets have low levels.
But diet still plays a significant role. Within the limits set by your genetic makeup, you can alter your blood-cholesterol levels and reduce your chances of developing heart disease by changing your diet. You can't change your parents, but you can modify your diet into a heart-healthy diet.
1. Eat fewer saturated fats and more polyunsaturates. The typical American takes in as much as 40 percent of total calories in the form of fats—and more than half of that is saturated fats. Saturated fat and trans fat are the bad kind. They usually come from milk, meat and processed foods. A far healthier ratio would be to reduce fat consumption to 30 percent of your diet and limiting 10 percent or less to saturated fats. To accomplish this, eat less red meat and drink less milk. If you eat red meat, trim all visible fat away before eating. Switch from whole milk and ice cream to skim milk and low-fat yogurt. Use polyunsaturated oils for cooking and salads. Eat fewer baked goods.
2. Consider a vegetarian, plant-based diet. Vegetarians generally have lower levels of blood cholesterol and a lower risk of heart disease than the general population. Vegetarians who subsist entirely on plant-based diets have extremely low levels of blood cholesterol. Regardless of your age, it's never too late to switch to this type of heart-health diet. If switching to an entirely plant-based diet is too radical a step, you can improve your blood cholesterol by substituting fish and skinless chicken for red meat and reducing your consumption of fatty foods. In recent years, there has been a decline in the number of deaths from heart disease which many researchers attribute to a lower national consumption of red meat.
3. Use more olive oil. Studies have shown that men in Italy and Greece—where olive oil makes up a large percentage of the total fat intake—have lower rates of heart disease than men who eat diets high in saturated and trans fats, like in the United States. Research has proven that diets high in monounsaturated fats (such as olive oil) are effective in lowering blood cholesterol.
4. Include more fiber in your diet. There are certain types of dietary fiber that can reduce your blood-cholesterol levels significantly. But it has to be the right kind of fiber and not simply wheat bran. It must be the water-soluble fibers found in oat bran, apples, dried beans and peas that will help.
By taking these steps and continuing to run, you can reverse coronary artery disease. It can be done, but you should first check with your doctor. And then you need regular check of your blood-cholesterol levels to make sure the dietary changes are working.
Different people respond differently to dietary and exercise changes, but these changes have worked in many high-risk, overweight people. The key is you must be willing to make a change—and stick with it. Dietary intervention works, but only if you make it a lifestyle change (including exercise) that you are willing to maintain.


After i have been asked several times about the 4-edged Sockets we use - here comes the answer. We now have them in stock in our Store area which you find in the upper navigation bar.
Those sockets are made out of wood from beech tree and are perfect to work with (hard wood). The sockets will be delivered to you smoothed and all in the same size. Size is 4 cm in every direction.
Get yours in the store.
What a nice idea - i should pick that up ^^.
what's this explorer guy on the first picture? He fits perfectly in my Darkest Africa collection...could you tell me were to buy it?


text:
New research reveals missing link between tumour suppressors and prostate cancer
A major advance in understanding of the role of a key tumour suppressor gene, PTEN, in regulating tumour cell growth has provided valuable insights for potential future cancer treatment – thanks to a highly productive, long-term collaboration between scientists at AstraZeneca and the Signalling Laboratory of the Babraham Institute, Cambridge.
The new findings, published this week in Molecular Cell, help to explain why loss of the PTEN gene in people with prostate and some breast cancers is so important. These findings may help identify patients most likely to respond to a new generation of targeted therapies.
"Over 40% of prostate cancers lose PTEN and some lose both PTEN and another tumour suppressor gene, INPP4B, but we didn't previously have a clear picture of how this affects tumour growth," says IMED Biotech Unit scientist Sabina Cosulich, at AstraZeneca. "The new discovery has given us an important link between the biochemical function of PTEN and its role in prostate cancer, and in some triple negative breast tumours for which treatment is currently limited."
The research brought together the complementary skills of the world-leading Babraham Institute molecular signalling group led by Dr Phill Hawkins and Dr Len Stephens and the oncology translational science expertise of IMED scientists.
Two research teams, one goal
By modifying previous techniques, the Babraham Institute scientists revealed that PTEN suppresses tumour growth not through one mechanism as previously thought, but two. They showed that, within the PI3K cell signalling pathway, PTEN regulates production of two lipid messengers. These are needed for activation of AKT – a protein that mediates cell growth and is a target for novel anti-cancer drugs.
We were really surprised that loss of PTEN caused such a dramatic increase in PI(3,4)P2 in our mouse model of prostate cancer. PI(3,4)P2 has generally been a bit of an enigma, with most scientists unsure of whether it acts merely as a degradation product of the accepted messenger molecule 'PI(3,45)P3', or it acts as an additional messenger in its own right. Recently however, several studies have provided compelling evidence that PI(3,4)P2 may actually regulate important components of cell growth and invasion. Therefore, our work suggests that studying some of these basic PI(3,4)P2-regulated processes may help us to understand why PTEN is such a powerful tumour suppressor and may also help us to identify new therapeutic targets in PTEN-mutated cancers
Dr Phillip Hawkins Babraham Institute
Using human prostate and breast cell lines, some with and some without PTEN, the IMED scientists validated the Babraham Institute findings, confirming the effects of PTEN on lipid messenger levels. They also contributed gene expression, metabolomics and RNA profiling data from a genetically engineered, PTEN deleted, prostate cancer model to corroborate subsequent studies by the Babraham Institute team.
"The joint data emphasised the importance of AKT as a target for cancer treatment, and the potential of the PI(3,4)P2 lipid messenger for helping to identify other drug targets, especially in patients whose tumours have lost PTEN and INPP4B," says Dr Cosulich.
Applying the science
AstraZeneca has an AKT inhibitor in development, with accompanying research into diagnostic tests for PTEN and other biomarkers intended to aid identification of patients more likely to benefit from treatment.
Other potential medicines targeting different steps in PI3K signalling are at various stages of development. But, as Dr Cosulich concludes, the Cambridge collaboration offers a winning formula for ongoing research:
"Having such an open collaboration was essential for addressing a scientific puzzle of great significance to cancer research. Our team members are in regular contact and frequently work alongside each other. Hearing about the lipid biochemistry research from the Babraham Institute team and realising how we could translate its potential from an oncology perspective was a great moment for all of us!"
Expand infographic


text:
Information published on 31 March 2020 in the UIC electronic newsletter "UIC eNews" Nr 685.
France: Medical TGVs run between Grand Est and Pays de la Loire
News from UIC members
Following an initial trip on 26 March (SNCF transported some thirty intensive care patients on behalf of the French Ministry for Solidarity and Health), two further medical TGVs transported 36 patients affected by Covid-19 from Nancy and Mulhouse to Nouvelle Aquitaine on Sunday 29 March. See details of the first trip below.
Preparations and travel
Healthcare personnel boarded the train and medical equipment was loaded onboard at Paris Est station on the afternoon of Wednesday 25 March.
The patients were transported to the TGV from 6 am on Thursday 26 March for departure at around 11 am. A first group of patients were taken to Angers, where the train was expected to arrive at around 3.30 pm. The other patients travelled in the direction of Nantes, with an expected arrival time of around 6.30 pm.
Team effort at SNCF
The entire SNCF team mobilised efforts after receiving a formal request from the authorities on Monday 23 March.
SNCF Réseau worked to define the specific train paths the train needed to run on the Est and Atlantique railway axes.
At the Gare de l'Est in Paris, the trains were loaded with provisions by station agents, while security personnel supervised set-up procedures for healthcare staff and loading of medical equipment. The supervision team also ensured that the train was secure overnight and that patients and healthcare personnel were transferred in the station, with signposting put in place with the help of Gares & Connexions staff. The train had to reverse direction in Angers, with a shunter in charge of stabling it.
The train had a driver, relayed at Massy, a traction manager and two train managers on board. They were supported by two drivers from the TGV driver support centre. The patients were given respirators, and an electrical service engineer from SNCF's "Technicentre Est Européen (TEE)" maintenance workshop was on board to manage the train's electrical power supply. These personnel travelled as a unit in the non-medical carriage of the TGV in order to keep contact with healthcare workers and patients to a minimum. The agents had all of the protective equipment (masks, suits, goggles, etc) required in the event of an emergency. The train was fully decontaminated upon its return from Nantes.
Christophe Fanichet, Chairman and CEO of SNCF Voyageurs:
"As a large public service company, SNCF rallies to give the best of itself and answer the call when it is needed, both in good and in difficult times. SNCF teams are once again demonstrating their sense of duty and their ability to work together to enable this train to run. My deepest thanks to them".
In addition, 12 coronavirus patients were transferred by French military helicopters from hospitals in eastern France to healthcare facilities in Auvergne Rhône-Alpes and Germany during the weekend of 28 to 30 March.
(Source: SNCF)
Belgium: Coronavirus – Lineas operations continue as normal – Extra measures taken China: Railway sector operates 300 migrant-worker dedicated trains to support work and production resumption Finland: Operability of transportation routes to be secured ILCAD 2020 launch conference in York postponed to June 2021 Passenger Experts Subgroup (PES) met remotely on 25 and 26 March 2020 South Korea: KORAIL's fast response to Covid-19 Spain: Online exhibition "Madrid-Delicias: 140 years of a station" TopRail: Tourism Potential of Railways remote meeting held on 24 March 2020 via webconference UIC actions on Covid-19 referenced in articles and communication UIC makes available audiovisual material on Covid-19 via its mediacenter
e-News articles with keyword Europe
24th plenary meeting of the European Level Crossing Forum (ELCF) (1 December 2020) Italy: Gianfranco Battisti: "Proud to export Italian excellence abroad" (1 December 2020) Germany: Major contract: DB Cargo to invest in logistics for steel giant ArcelorMittal in Eisenhüttenstadt (30 November 2020) Latvia: LDz and RZD discuss possibility of launching passenger transportation on the St. Petersburg – Kaliningrad route (30 November 2020) Belgium: SNCB is nominated for the Covid-19 Outbreak Special Award (23 November 2020)
e-News articles with keyword News from UIC members
Latvia: LDz and RZD discuss possibility of launching passenger transportation on the St. Petersburg – Kaliningrad route (30 November 2020) Belgium: SNCB is nominated for the Covid-19 Outbreak Special Award (23 November 2020) Norway: Bergen gets Norway's greenest freight terminal (20 November 2020) Amtrak: 18 November 2020 Amtrak continues to enhance the travel experience at New York Penn station with new safety features and amenities (20 November 2020) Germany: Major contract: DB Cargo to invest in logistics for steel giant ArcelorMittal in Eisenhüttenstadt (16 November 2020)
e-News articles with keyword Covid-19
13th UIC Covid-19 Task Force web-conference held on 20 October 2020 (20 October 2020) UIC to chair International Railway Summit webinar on crowd management in stations during Covid-19 (15 October 2020) 6th edition of UIC World Congress on Rail Training: "Unite, Inspire, Connect" (7 October 2020) CIT/UIC Conference of Passenger Claims Departments (1 October 2020) Meeting of the UIC Security Platform Steering Committee held online on 29 September (1 October 2020)


Hale Scout Reservation is a 480-acre Boy Scout Adventure Camp located in the beautiful Winding Stair Mountains in Southeastern Oklahoma. Nestled in the Ouachita National Forest, Hale Scout Reservation is a premier summer camp destination for Boy Scout Troops from many surrounding states. The camp operates 9 weeks each summer with more than 7,000 Scouts and leaders in attendance. Hale Scout Reservation provides Scouts of all ages with rugged outdoor challenges, high adventure, beautiful scenic views and one of the best summer camp experiences in the nation.