WRONGFUL DEATH: A Medical Tragedy by Sandra M. Gilbert (W.W. Norton: $22.50; 365 pp.). Your beloved spouse of 30-odd years has just died, quite unexpectedly, following fairly routine surgery for prostate cancer. What does the doctor say, a physician you chose for his nationally recognized expertise, his charming brogue and beside manner? "I know, I know, for you this is unpleasant, awful, but believe me for me it's shattering ." When first encountered in Sandra Gilbert's "Wrongful Death," this remark appears laughably insincere, impossibly arrogant, but makes sense soon enough--when it becomes clear the doctor knows he probably made a fatal mistake, in either the operating or the recovery room, following surgery upon UC Davis English professor Elliot Gilbert in 1991.
Gilbert's widow, a distinguished poet and critic and co-author of "The Madwoman in the Attic" and other books, does indeed tell "a medical tragedy" in this volume, for there's little question--even though the survivors' wrongful death lawsuit never went to trial--that UC Davis' doctors were negligent. "Wrongful Death" is an anguished j'accuse, to be sure, but it's also a loving eulogy and, most of all, an unwavering, impassioned inquest as Gilbert attempts to determine the immediate cause of her husband's medical "termination." Elliot Gilbert joked before the operation that "the chair of urology can't kill the chair of English," but his faith seems to have been misplaced, for the most plausible reading of Gilbert's appallingly contradictory, incomplete medical records indicates that he was allowed to bleed to death from internal hemorrhaging. Did a suture fail? Was a critical blood test misplaced or disregarded? Were many distinct signals of patient trauma ignored? Was there a cover-up of the true cause of death?
Sandra Gilbert will never know the answers to these questions, and one can only empathize with her long-lasting emotional denial, her desire to sleep in hopes that Elliot will somehow magically wake alongside her. "Wrongful Death" is a powerful and wrenching book, and it's deepest message loud and clear: That although survivors will eventually come to terms with the unexpected death of a loved one in medical care, they will always remember and resent a doctor's refusal to be candid about the circumstances.


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Sorry, British royals: Netflix will not be adding a "this is all fiction" disclaimer to The Crown
Sam Barsanti
Today in news that might be taken as a bit of a bother by exclusively one fancy family and the people who care too much about them, Netflix has released a statement saying that it will not be adding a disclaimer in front of episodes of The Crown to make it explicitly clear that the show is, in fact, a fictionalized drama based on historical events and not some kind of direct cinema documentary where Netflix put cameras around Queen Elizabeth II and just watched her go for 60 years.
This all started last week, when U.K. culture secretary Oliver Dowden suggested to The Daily Mail that there was a danger of an entire generation of TV viewers growing up under the impression that the events of The Crown all really happened—a concern that is slightly more pressing now that the show's timeline has gotten a little closer to the present day. The implication is that the show's depiction of certain members of the British royal family might not be as positive as the family and its most loyal supporters would hope, so younger viewers might come away thinking that things happened in real life exactly as they did in the show.
But no, according to Netflix, people are actually smart enough to recognize the difference between TV and real life (a rare vote of confidence from a tech company). As reported by Variety, a Netflix spokesperson has explained that the service has "always presented The Crown as a drama," and so it has "every confidence our members understand it's a work of fiction that's broadly based on historical events." Variety also notes that Dowden sent Netflix a "private letter" about this issue and that the company sent him a private response, but we don't have any details about that. It does seem to indicate that you can get personal responses from Netflix if you're in a suitably important government position. Any fans of The OA working in a high-level position out there? Here's your chance!

redpajama_set_name: RedPajamaCommonCrawl


When I checked in for my 1:40 lunch reservation I decided to ask if I could be seated outside on their terrace. I had two reasons for doing this. The primary one is that I remembered that on my last two visits to Tony's it had been pretty loud when seated inside in the main dining room. But also, I thought the terrace might provide a decent view for the afternoon parade (Festival of Fantasy) if I should happen to still be there at 3:00 (or actually 3:30ish, as the parade started in Frontierland and ended in Town Square that day).
And I was there for the parade. In fact, my entrée was not even brought out until the parade had already reached Town Square. But let me explain… After checking in for my reservation I took a seat in their crowded waiting area. I figured that with the specific seating request I might be in for a long wait but I was okay with this since I had a comfortable couch to sit on, plus I wasn't very hungry yet after a big breakfast at Crystal Palace. Well, at about 2:30 I decided to return to the desk and ask if I could be seated at whatever table for one (or two) was next available. Well they couldn't find the ticket for my reservation, hence my loooooong wait. As it turned out they found it with those of the guests who had already been seated. So with that mistake corrected it wasn't too much longer before they found me a table…on the terrace.
I've had this before and really enjoyed it. And happily it was again very good. Ideally I would have had someone to share this with though, since it was too much for just one person.
Especially one that also had this big plate of pasta to eat..
While it wasn't the best view I've ever had of the parade, the terrace is elevated just enough that I had a decent view over the crowd while still comfortably seated at my table.
I had one of these with my spaghetti and it was very good.
Too full for dessert, so that just leaves the ratings and rankings. While the food was pretty good, the service was somewhat lacking so I would only rate it a 3. Yelp reviewers also gave Tony's a 3, but it fared a bit better on Trip Advisor with a 3 1/2. As for the ranking, it comes in at #609 of the nearly 3,000 Orlando area restaurants reviewed there (or #177 if narrowing it down to just the Disney World area restaurants).


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Q: Count with several conditions - oracle sql Im trying to do a count of particular transactions that have specific conditions and cant seem to make it work.Also in the query I select other columns from other tables
for example:
Want to select all transactions

*

*where transactions.ID_1 = transactions.ID_2,

*where transaction.dir = "outbound"  and transactions.status in ("completed", "processing")
and do a count on this. like:
  select
  m.ID
 ,m.Number
 ,t.Status
 ,(column that counts of all transactions with the conditions mentioned above)
 ,p.label

 from module m
 inner join transactions t on t.ID_1 = m.ID
 inner join process p on p.ID = m.ID`

Tried with sum and when and if statement but doesn't work

A: I consider this is a simple count you can use the next script:
SELECT COUNT(transactions.ID_1)
FROM YOUR_TABLE
WHERE transactions.ID_1 = transactions.ID_2
AND transaction.dir = "xxx"
AND transactions.status in ("a", "b")

A: Seems like you want to GROUP BY. Use a CASEexpression to do conditional aggregation.
select
  m.ID
 ,m.Number
 ,t.Status
 ,SUM(case when transaction.dir = 'outbound'
            and transactions.status in ('completed', 'processing') then 1
           else 0
      end)
 ,p.label

from module m
 inner join transactions t on t.ID_1 = m.ID
 inner join process p on p.ID = m.ID
group by m.ID
 ,m.Number
 ,t.Status
  p.label

redpajama_set_name: RedPajamaStackExchange


In treating faces toward the Divine Proportion, Dr. Jefferson discovered that certain medical problems may alleviate the symptoms of certain systemic diseases, syndromes, or conditions. There may be a correlation between Divine Proportion and health.
When the human body develops toward the Divine Proportion, it upholds the first law of "conservation of energy," which means that there is maximum performance with minimum effort.
It also upholds the second law of "conservation of tissue," which means that minimum amount of cells and materials are employed to perform the needed task.
Reference: Rickett RM. The biologic significance of the divine proportion and Fibonacci series. AJODO 1982;81:5; 351-370.
1. Fonder AC. The Dental Physician.
Nasal congestions and sinusitis, mouth breathing, headaches, migraines, temporomandibular disorder, ear infections, ringing in the ear, hearing loss, dizziness, neck-back-shoulder pain, curvature of the spine, inability to sleep, skin disorders, hypertension, attention deficit and hyperactivity, asthma, respiratory problems, throat infections, Down syndrome, seizures, etc.
39 year old clergyman with scoliosis and psoriasis treated with molar support to harmonize the facial-skeletal problem.
be improved by harmonizing the facial-skeletal disharmony.
Harmonizing facial-skeletal disharmonies may alleviate TMD symptoms, pain, stress and some cases skin disorders.
Harmonizing the facial-skeletal structures may alleviate other medical symptoms.
11 YEAR OLD, DIAGNOSED AS MICROCEPHALIC WITH THE EPICRANIUS NOT FULLY DEVELOPED.
Harmonizing the facial-skeletal structure helped to alleviate multitude of medical problems in this child including improved posture, improved respiration, decreased grand mal seizures, decreased depression, increased mental acuity, etc.
16 YEAR OLD DOWN SYNDROME TREATED 6 ½ MONTHS WITH SURGICAL EXPANSION OF THE PALATE.
Note improved facial features. Other improvements were noted such as improved breathing, physical development and maturation, and improvement in intelligence.


Xinha needs the variable '''_editor_url''' to be activated.
you may try a relative URL if you wish, but it's highly recommended to use an absolute URL.
It is only needing to set the variable '''_editor_lang''' to the wanted language. Set here to '''"en"'''.
This language can not be updated once Xinha script is loaded.
It is of course needed to include the main script. Which could actually looks like the following code.
The TEXTAREA that's need to be turned into a Xinha editor, absoluty require an ID, uniq ID obviously.
It is needed to make a function to start the editor that we will trigger once the document is loaded.
In this function, we will do basic initialisation such as creation of the configuration object and editor start.
Which finally give the following result.
Ok there's a lot more you CAN do if you want, read the [wiki:Documentation/NewbieGuide] if you want to learn how.


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South_Sudan_2015_Jeffrey_Abyei_329314.JPG
Women kneel during a Palm Sunday Mass at the Catholic Church in Abyei, a contested region along the border between Sudan and South Sudan. Under a 2005 peace agreement, the region was supposed to have a referendum to decide which country it would join, but the two countries have yet to agree on who can vote. In 2011, militias aligned with Khartoum looted and destroyed much of the church and drove out most of the Dinka Ngok residents, pushing them across a river into the town of Agok. Yet more than 40,000 Dinka Ngok have since returned, with support from Caritas South Sudan, which has drilled well, built houses, opened clinics and provided seeds and tools for the returnees. Yet violence has continued, with a March 1 militia attack killing four residents, according to the United Nations.
contested area
border region


text:
This full day tour will take you through Glengesh Pass, Glencolmcille, Muckross Head and Malin Beg.. we'll stand atop (almost) the highest sea cliff in Europe and time/weather permitting, we'll see it from a boat that operates from one of the oldest piers in Ireland. We'll be taken back in time in authentic period cottages getting a feel for how our ancestors lived and traveled in an antique train as well as watching one of the oldest working weaving mills in action! Yes.. it's a 'full' day! :) .
Cost of this tour is €500.00 total for group of up to 4. You can secure your intended date here with our required deposit of 150.00 Euro with the remaining balance to be paid 2 weeks prior to date of commencement. We're looking forward to meeting you!
Secure Your Date
Brief Description of Attractions included on this Tour...
Fintown Historic Railway
The Fintown Railway is the only operational railway in Co. Donegal. Set amidst spectacular highland scenery overlooking Lough Finn, the railway (3 m/5km) is a restored section of the former County Donegal Railway. This setting prompted the famous international playwright Brian Friel to pronounce "What is on offer is a unique journey along the shores of a lake as grand as any in Switzerland or Minnesota" The railway nestled deep in the heart of spectacular mountainous scenery steeped in tradition, myth and folklore, and running along the crystal clear waters of Lough Finn is a million miles from the constant rush of every day life. You are invited to relive those bygone days when Donegal had 200 miles of narrow gauge railway operated by the Counties Donegal and Londonderry & Lough Swilly Railway Companies.
Fr. McDyer's Folk Village
The Glencolmcille Folk Village Museum is a cluster of six small cottages, called a "clachan," perched on a hillside overlooking a sandy curve of nearby Glenbay beach. In 2011 we look forward to opening two new exhibition houses - a traditional thatched shop/pub with a shoemakers in the lower room, and a Fisherman's cottage dedicated to our history concerning the local fishermen and the sea.
The cottages are neatly white-washed, each with a traditional half-door, designed to keep the animals out and the people in.
The roof of each cottage is thatched in the distinctive rounded Donegal style, tied down securely with rope and pegs to protect the thatching from the fierce westerly winds off the ocean.
The Folk village Museum offers an excellent guided tour for the visitor. In the tour you will experience life as it was in the 1700's, 1800's and 1900's. Our thatched cottages are exact replicas of those belonging to that era and are furnished accordingly. Take a look at how our ancestors lived, cooked, the beds they lay on, the tools they used, their means of lighting and heat. For those of you who can trace your ancestors to Ireland, this is an ideal opportunity to see rural life at first hand.
Slieve League
Slieve League will take your breath away, that is a promise - the cliffs of Slieve League in Donegal are the highest accessible sea cliffs in Europe. A nearly sheer drop of roughly 2,000 feet separates the Atlantic Ocean from the highest point and a guaranteed lethal drop, Slieve League is the thinking man's alternative to the Cliffs of Moher offering a much more natural and uncrowded experience. Why then is this cliff face in Donegal not more popular? Location, location, location!
Triona Weaving Mill
Located in Ardara, Co. Donegal, 25 years of keeping alive the tradition of handwoven Donegal Tweed and Irish Produce.
Having 5 generations of weavers in the family keeping alive such an art is not an easy task and so has earned Triona Design numerous Failte Ireland Awards and Donegal enterprise Awards.
There are many aspects of Triona Design that make it unique , the fact the majority of the fabric and garments are manufactured on the premises and only sold in their shop or on line.
This leaves authenticity that is not found elsewhere with an array of fabrics ranging from tweeds, fine wools , lambs wool from the local sheep dyed and spun locally in the colours of the rugged landscapes of Donegal and put into traditional design capes, coats, jackets and also mixed in with a touch of modern up to the minute trends.
Sleive League Boat Trip
Weather permitting, We run tours to the Sliabh Liag Cliffs, the highest accessible sea cliffs in Europe standing 600m (1972 feet ).
We can get close to the shore to appreciate this spectacular sight. The tour lasts about one and a half hours, and we take in many wonderful sights.
Sometimes we are joined by wild life, like dolphins, whales, seals, and in May and June we often see basking sharks feeding on the plankton.
There is also a wide range of bird life that can be seen nesting and hunting. You can go swimming or snorkeling in the crystal clear water of the many coves on the tour. A unique experience for everyone.
Let's make it a Brilliant Day!!


Meet the Survival Frog EDC Carabiner: a handy multitool designed to get you unstuck outdoors. It comes with a 3.5″ sharp knife that can cut and slash anything. It has a 440c stainless steel construction. You also get a LED flash light and a flat head screwdriver.
This carabiner gives you access to 7 tools to get you out of trouble. You can get it for under $20 at this time.


The optical notebook mouse from ednet is less susceptible to interference. The high accuracy of the optical sensor allows for precise positioning of the cursor. The scroll wheel with key function makes operation easier and more convenient. This mouse also feautres a retractable cable, with cable storage in the housing the optical notebook mouse, making it an ideal travelling companion.


Decorating Ideas For Apartments. You most likely already know that Decorating Ideas For Apartments is one of the hottest topics on the net nowadays. According to info we had from adwords, Decorating Ideas For Apartments has a lot of search online search engine. We expect that Decorating Ideas For Apartments supply fresh thoughts or references for followers.
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We sincerely hope that what we give to you could be useful. If you want, you can share this post for your companion, family, neighborhood, or you can also book mark this page.


So, Thanksgiving has come and gone… You may feel full now, but Saxelby Cheesemongers suspects that you'll have room for more noshing soon enough! After all, isn't that what the holidays are for?! Just in time for the festivus season we've created a divine porcine (and bovine and ovine) holiday gift selection entitled Pasture and Pâté. Don't know what to bring to that holiday get together? Don't know what to send that food lover in your life for the holidays? Look no further! It doesn't get much more delicious than this. Order one for pickup at the shop or ship anywhere in the US of A by ordering online at saxelbycheese.com!
Includes one half-pound piece of savory pâté and three half-pound wedges of fine American farmstead cheese.
This is what happens when pastoral worlds collide! Three rustic American farmstead cheeses meet locally produced country pâté in this unbeatable holiday gift selection. Gabriel Ross, a New York charcutier, has crafted a limited run of his sublime 'Trotter Terrine' specially for Saxelby Cheesemongers. Gabe's hearty pâté is the perfect protein-laced foil to Saxelby's selection of delectable cheese. Each Pasture and Pâté selection includes a half-pound piece of pâté, and three half-pound wedges of hearty cheese: Cabot Clothbound Cheddar, a sweet and caramelly cheddar laden with pockets of crystalline crunch, tart and tangy Landaff, from New Hampshire, a Welsh-style cheese with an earthy finish that renders it perfect for all snacking occasions, and last but not least, Vermont Shepherd, a nutty and downright mutton-y cheese with a complex, grassy finish. Add some delicious to your holiday nosh with Saxelby Cheesemongers' Pasture and Pâté!
Till next week, eat cheese and be merry!


Buying or selling a vehicle can be stressful. The frustrations of haggling and feeling pressured to make a hasty sale or purchase can cause hours of indecision. Plus, trying to decipher what forms and applications to sign and send can add to the uncertainty.
To make the process easier, take heed of the following tips.
Always have the vehicle inspected by an independent mechanic of your choice.
Investigate the car's history. Request the name and address of the previous owner if you are buying from a dealer.
Make sure the vehicle identification number (VIN) on the car matches the VIN on the title.
Insist that all agreements be made in writing.
Be sure the seller gives you a Bill of Sale and Odometer Disclosure Statement (Form VT-005), the title, and a receipt.
Before walking into a dealership, take the time to learn the trade-in value of your car by looking it up on the Kelley Blue Book website.
Know how much you can afford, and compare finance terms between the dealer and your bank before expressing interest.
Don't succumb to the pressure tactics of a zealous dealer. You're the one who must live with your decision. And bear in mind that there is no hedging once you sign the contract.
Get every agreement in writing.
Be sure you get a Bill of Sale and Odometer Disclosure Statement (Form VT-005), a Manufacturer's Certificate of Origin, and (if the car was bought in Canada) a New Vehicle Information Statement.
Submit all the above forms along with a completed Registration Tax and Title Application (Form VD-119) to the main Vermont Department of Motor Vehicles office located at 120 State St in Montpelier.
Keep in mind that the state does not require titles for vehicles more than 15 years old. If you are attempting buy or sell such a vehicle, make sure that the Bill of Sale and Odometer Disclosure Statement (Form VT-005) includes the vehicle's make, year, vehicle identification number, purchase price, odometer reading, date of sale, and seller's signature.
If you are buying or selling a vehicle that does not have a required title (15 years old or newer), you will need the original or certified copy of the vehicle's last registration certificate as well as a Bill of Sale and Odometer Disclosure Statement (Form VT-005) that includes the vehicle's make, year, vehicle identification number, purchase price, odometer reading, date of sale, and seller's signature. If the vehicle is nine years old or newer, you'll also need to complete the odometer disclosure statement on the back of the bill of sale.
Keep in mind that an expensive vehicle does not automatically translate into a good vehicle. Pricey cars are just as prone to maintenance breakdowns as lower-priced models.
The best deals for new cars occur July through October, when dealerships are trying to create space for new models, and during late December, when salesmen are desperately trying to reach year-end quotas.
Don't let the dealership hang onto your driver's license for collateral while taking a test drive. While you're wheeling around the block, the dealership could be using your license to run an unauthorized credit report.
To allay fears of getting stuck with a dud, Vermont does have a Lemon Law in place to protect you from getting fleeced by an unscrupulous car dealer. This does not guarantee it won't occur, however. You still need to exercise good judgment when negotiating with an unknown dealer.


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IWC Pilots 36 Watches
When IWC created its first Pilot's Watch in 1936, a legend was born. The brand has become synonymous with exceptional aviation watches, and its Pilot's Watch line has become an icon in horology. Inspired by cockpit instruments, IWC Pilot's Watches are built intuitively for aviators of all kinds, both professional and enthusiast alike.
Bronze (1) Steel (2)
Black (1) Blue (1) Green (1)
Pilots 36
Age: Less than a year (2019)
Feature: 5 Alternatives To The Rolex DateJust
Sometimes answers are so obvious it's barely worth asking the questions. If you want a sporty two-plus-two, for example, that handles like a racer yet will happily sit in a Monday morning queue, you get a 911. Or, if you want a 3-hander that's both rugged and elegant, you get a DateJust. It's practically written in the stars, but yet—sometimes what seems to be the right answer isn't always the best answer. That's why cars like the McLaren 540C, Aston Martin Vantage and Audi R8 exist, and it's why the watches you're about to see exist as well.
Feature: The Dream Watch Collection: Part 2
It's time for another trip into the world of our imaginations as we wonder what it's like to buy whatever watch we want. And why not make it three while we're at? For this dream watch collection, we've assumed the persona of a traditionalist, someone who likes their watches with a more classical taste—but with a bit of a twist.
Feature: Alternatives To The Audemars Piguet Royal Oak
We've all been there, looking at the world's first luxury sports watch, Audemars Piguet's game-changing Royal Oak, thinking, "I wish." For the lucky few who get to own one, they can enjoy the defining work of one of watchmaking's most influential designers—but not everyone can be so fortunate. But it's not game over just yet because we've got a selection of watches that just might scratch that itch without costing anywhere near as much.
Feature: 3 Watches To Wear With a Suit
Everyone loves a good sports watch, but there's nothing quite like a smart timepiece to spruce up a suit and tie. Smart watches can be a little, how do I say this, boring at times however—but that doesn't have to be the case. Here are three examples to prove it.


NYT, the wealth-inequality survey by Michael Norton and Dan Ariely is back in the news.
The respondents were presented with unlabeled pie charts representing the wealth distributions of the U.S., where the richest 20 percent controlled about 84 percent of wealth, and Sweden, where the top 20 percent only controlled 36 percent of wealth. Without knowing which country they were picking, 92 percent of respondents said they'd rather live in a country with Sweden's wealth distribution.
Similarly, Tim Noah, in Slate, said the survey showed respondents favoring "a wealth distribution resembling that in Sweden". And Chrystia Freeland has the same idea: "Americans actually live in Russia, although they think they live in Sweden", she writes.
The Norton and Ariely paper is easy to misread in this way. Americans Prefer Sweden is one heading; the text does little to dispel that idea.
As can be seen in Figure 1, the (unlabeled) United States distribution was far less desirable than both the (unlabeled) Sweden distribution and the equal distribution, with some 92% of Americans preferring the Sweden distribution to the United States. In addition, this overwhelming preference for the Sweden distribution over the United States distribution was robust across gender, preferred candidate in the 2004 election and income.
Pie charts depict the percentage of wealth possessed by each quintile; for instance, in the United States, the top wealth quintile owns 84% of the total wealth, the second highest 11%, and so on.
We used Sweden's income rather than wealth distribution because it provided a clearer contrast to the equal and United States wealth distributions; while more equal than the United States' wealth distribution, Sweden's wealth distribution is still extremely top heavy.
The point here is that wealth inequality is ever and always enormous. The US and Sweden are very far apart, when it comes to inequality, but if you look at wealth inequality rather than income inequality — which is the subject of the Norton and Ariely paper — then countries tend to look more alike than different. A huge part of the population of just about every country is going to have zero wealth — if you live paycheck to paycheck, for instance, or if you're young and haven't been earning money for long, or if you just spend a lot. That doesn't mean you're poor.
Indeed, Sweden and the US are even closer together, in terms of wealth inequality, than the charts above suggest: as Gimein notes, the Swedish data exclude money held offshore, the value of family owned firms, and the considerable wealth of super-rich Swedes like Ikea founder Ingvar Kamprad, who left the country to avoid taxes.
Ariely told Gimein that "we created a more equal society than the most equal society in the world," while calling it "Sweden". Which might be interesting as an academic exercise, but the message was lost on most of the people who read the paper, and who thought that there really was a society where the lowest quintile owns 11% of the wealth.
Wealth inequality is a problem — but it's one of those things, like homeownership rates, where public policy only makes a very small difference to some very large numbers. Norton told Gimein that he and his colleagues are now exploring "whether educating Americans about the current level of wealth inequality (by showing them charts and pictures) might increase their support for policies that reduce this inequality." Well, it might. But it's important not to mislead people about what's possible.


Samsung is open to an artificial intelligence partnership with Google, the company's President and Chief Executive Officer Kim Hyun-suk said while speaking to journalists at this year's iteration of IFA trade show in Berlin, Germany. The industry veteran acknowledged that Samsung's ambitions in the AI segment are directly rivaling those of Google, particularly given its focus on developing Bixby into a full-fledged ecosystem. Regardless, the Seoul-based technology giant is still open to a collaboration with Google and would even be able to leverage its status of the world's largest smartphone vendor in order to kickstart such a partnership, Mr. Kim said.
One example of such a partnership would be a deeper integration of Google-made services such as Maps and Search into Bixby, according to the executive. "Collaboration is essential for perfect voice control," the CEO asserted, having also referred to Samsung's global device sales that are in the ballpark of half a billion units per year as a user base that Google wouldn't be wise to ignore. Alphabet's subsidiary has so far been extremely inclusive in regards to widening its Google Assistant ecosystem but showed little interest in supporting any direct rival such as Amazon's Alexa. The latter adopted a more collaborative approach akin to the one Mr. Kim described last week, as evidenced by its partnership with Microsoft's Cortana. Samsung's massive install base should still allow the company to negotiate its way to a certain "level of cooperation with AI leaders," Google included, the executive maintained.
With Bixby being set to receive support for third-party apps this November and Samsung's first smart home speaker being scheduled to debut in the coming weeks, the South Korean tech juggernaut will be challenging Google's smart home offerings in the most direct manner to date and it's presently unclear whether a collaboration with the Mountain View-based company is something it will be actively pursuing in the near future. Google is expected to debut new AI-powered consumer electronics in early October, including the Pixel 3 line of Android flagships.


A popular restaurant wants to reward you for your food choices.
Barberitos Southwestern Grille & Cantina recently launched a free mobile app which provides incentives for loyal customers.
The app is designed with a robust rewards system that will send promotions and offer free items that are available exclusively for Barberitos app users.
The mobile app allows customers to pay using their mobile phone. It also assists hungry patrons with a menu on the go and allows them to find their nearest location and receive driving directions. Patrons can even review their transaction history right from their screen and reach out with questions, comments or concerns directly inside the app.
Local Barberitos lovers can participate in the rewards program at two CSRA locations: 1151 Agerton Lane in Augusta and 4272 Washington Road in Evans.
This entry was posted in New / Expanding Business, Restaurant News by Kelsey Morrow. Bookmark the permalink.


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HomeParanormalBlind Date with a Supervillain: Supervillain Romance Project
Blind Date with a Supervillain: Supervillain Romance Project
By (author)H. L. Burke
Juggling life as a superhero with college and a social life is hard, but Shawn Park, AKA Surge, feels he's killing it. Things look even brighter when he makes a connection with the sweet but shy new barista at his favorite coffee shop. Maybe a guy really can have it all … but appearances can be deceiving.
Apparition just wants her supervillain father to be proud of her, and she'll do anything to accomplish that: even disguise herself as mild-mannered coffee shop employee Nikki to get close to the superhero he's stalking. However, between his charming smile and kind words, she finds herself hopelessly drawn to the good natured Shawn.
As the chemistry between Shawn and Nikki sizzles, the tension between Surge and Apparition grows. If he finds out the truth, they could be headed for something far more explosive than the average breakup.
B08NHZPH7H
H. L. Burke
Caught By the Dragon: Maiden to the Dragon #1 (Alpha Dragon Shifter Romance)
Mac Flynn
An unexpected journey to an unexpected love Miriam Cait seeks love, or rather, her friend seeks it for her. Her friend's latest date suggestion is refused on account of his dark eyes. There's something not quite right with them, and Miriam soon finds out why when he comes knocking on her door, and knocking her out. Miriam wakes up from the confrontation with more than just a headache. Shackles cover her ankles and wrists, and she's on her way to being auctioned off to a bunch of self-proclaimed dragon lords. It all seems too fantastic to be real, but as the evidence starts mounting against sanity Miriam realizes she may be in deeper trouble than she thought.
Belle of the Ball: Three Graces Trilogy, Book 1
Pam McCutcheon
Beauty, Charm, and Grace—something the nouveau-riche Sullivan sisters of Colorado Springs lack. But a wish at a magical rock formation is about to change all that, in a most a-MUSE-ing way. . . . The three Sullivan sisters, named for the Three Graces of Greek legend who embody beauty, charm and grace, don't live up to their names. Belle is no beauty. Charisma lacks charm. And Grace is somewhat less than graceful. But this doesn't deter their ambitious mother from bribing three bachelors to escort them to Colorado Springs' beautiful Garden of the Gods. When the girls overhear their escorts mocking how little they resemble their names, each girl makes a wish at the magical Three Graces rock formation. Belle wishes aloud for beauty, but only so she can use it as a weapon to punish the cads who hurt her sisters. Her true wish is for revenge. Handsome viscount Kit Stanhope regrets his rude remarks and apologizes to Belle. He's surprised when she tells him that's not enough. If he truly regrets his behavior, he has to make her beautiful in time for the Founders' Day Ball. Kit isn't sure he's up to the task. But, intrigued by the spirited Belle, he agrees to assist her transformation from an ugly duckling into a swan with the help of a mysterious Greek dressmaker with muse-like qualities. Unfortunately, Belle makes a rather awkward swan. Still, after a few embarrassing escapades, she masters the flirtatious language of the fan and takes the town known as Little London by storm. Belle soon finds herself falling for the viscount and his sinful mouth. It seems he returns her regard, but she can't renege on her promise to humiliate him . . . can she? Will her secret muse grant the wish she voiced . . . or the one she holds in her heart? Note to readers: This title was originally published in 2003 by Zebra Ballad.
Time Thief (Anomaly Series Book 1)
Anna Hackett
"A fabulously steamy novella. Time Thief is filled with blood-pumping adrenaline and passion." – Kate, Goodreads review For a limited time, you can get the Anna Hackett Action Romance Box Set (containing three action-packed romances), free. Visit here to find out more >bit.ly/annahackettbooks (paste into your browser) Bay North wants revenge, no, she craves revenge. Hunted for her psychic ability to steal time and forced to watch her family die, all she wants is to make the crime lord who's taken everything from her pay. But now he's set the ultimate hunter on her trail and Bay will need all her skills just to survive the gray-eyed, hard-bodied man out to kill her. Ex-Navy SEAL Sean Archer has nothing left but a thirst for vengeance. After his team is killed in Afghanistan by a time thief, he came home a broken man. Now he hunts any of the monsters he can find, ready to rid the world of the dangerous mutation. But when he finally tracks Bay to Denver, he doesn't see a monster or a mutation, he sees a tough, beautiful survivor who ignites a desire he can't deny. During a shootout, hunter and hunted find themselves thrust into a reluctant alliance that shatters all their defenses. Can Sean convince a woman honed in revenge that they can have more than vengeance, blood and killing? Note to readers: This fast-paced novella contains a lot of action and adventure (think gunfights, car chases and a little breaking and entering), cool superpowers (stopping time and mind control) and a steamy romance (lots and lots of sexy steam between a muscled former SEAL and a gutsy time thief). It's a little bit paranormal romance, a touch science fiction romance with a side of romantic suspense. So if you like it fast, and fun, and sexy, this is for you! Includes preview of Book 2 of The Anomaly Series, Mind Raider.___________________________________________________ If you like action romance, there are more sexy anomalies for you to enjoy: Time Thief - Download for FREEMind RaiderSoul StealerSalvation What readers are saying about the Anomaly Series: "Fast paced, great characters, hot love. Hackett's heroes are constantly drool-worthy." "I devoured Time Thief in one sitting and enjoyed reading every page of it." "Loved reading every minute of Mind Raider and without a doubt, this will be a reread for me." "As I was reading, this story played out like a movie in my head due to the flawless storytelling and vivid imagery." "A delicious combination of action and sensuality, which is frankly irresistible." "This is romantic suspense with high stakes and hot sexiness." "The elements of danger, suspense, romance and good vs evil were absolutely brilliantly depicted." "Rich with emotions, a fully developed plot and storyline and memorable characters, Soul Stealer was a fantastic read." "Read in one sitting, I loved the fast paced, pull no punches action that each page contained. Soul Stealer is full of twists and turns that I didn't see coming. My heart is still racing as I write this!" "Fans of paranormal/sci-fiction romance need to pick up Salvation along with the rest of the Anomaly Trilogy. Don't miss out!" About Anna: I'm passionate about all things action romance. I love stories that combine the thrill of falling in love with the excitement of action, danger and adventure. I write about people overcoming unbeatable odds and achieving seemingly impossible goals. I like to believe it's possible for all of us to do the same.
Beast Billionaire #1 (Bad Boy Alpha Billionaire Werewolf Shifter Romance)
Fate has much in store for Maggie O'Hara as her journey into the paranormal begins with a pink slip. When her father is wrongfully fired from his job she's determined to right the wrong and takes the drastic measure of visiting her father's employer, the reclusive Randall Forrest. Her escapades into espionage get her caught, but the consequences are not what she expects.
Oracle of Spirits #1: BBW Werewolf Shifter Romance
Strange noises. Haunting shadows. A handsome man with a mysterious past. Enid Runa doesn't ask for anything or anyone to slip into her life, but fate deems her destined for an adventuresome life that begins with a shadow and ends with her being carried off into the night. Her captor is the enigmatic and flirtatious Ian Osman, a man with a lot of secrets and more than one interest in her. He tells her that she's entered the world of the paranormal, and he's her only safe ride through the fun land of horror that has their blood-red eyes set on her. She doesn't know whether to slap Osman or hug him, and matters are complicated when she learns his darkest secret.
Highland Moon #1: BBW Scottish Werewolf Shifter Romance
Life is short in the old village where Muira, a young girl blossoming into womanhood, has spent all her days, but her life is about to begin when she begins her new position as servant to Castle Campbell. The old laird and the old castle are cold compared to her home with her mother and brother, but the innocent girl will learn the pleasures of womanhood when she stumbles on a dark secret. The secret consumes her and leaves her breathless for more of what she knows is sinful, but nobody told her sin would feel so good.
The Devil In Disguise (Bad Things Book 1)
Don't make the devil angry… Luke Thorne loves having one hell of a good time. As the ruler of every dark creature to walk the earth, he certainly has more than a bit of a bad side. He lives for danger and isn't the type to lose his heart—mostly because he doesn't have one. Then she walks into his life. Mina James is seduction in the flesh, a perfect temptation that the devil himself couldn't pass up. Too late, Luke realizes he's let a real siren into his life, a woman who is bent on using his dark powers to free herself from hidden enemies. Since Luke isn't the type of man to be used, he should walk away from her, but…something about Mina draws him close. Soon he's realizing that she isn't who she appears to be. Not dark and cold, but burning red hot. Mina is a woman fighting for her life—and the Lord of the Dark suddenly finds himself in an unlikely role…hero. Luke isn't going to let her enemies destroy Mina. He will fight heaven and hell to keep her. But in the end, the secrets they both carry may just rip apart a love that should never have been… There are Bad Things in the world…very, very bad. Are you ready for them?
Change (Kitsune Book 1)
Newly revised and edited November 2017A rattlesnake bite. A moment of panic. Everything changed in the blink of an eye Nickie learns the hard way, not only do shapeshifters exist, but she is one. Now she's learning to deal with increased speed, strength and healing and at the same time, thinking she's losing her mind because suddenly, she can hear things. To add to her challenge, Nickie's learning that people she thought she knew have secrets she never imagined. Can Nickie navigate all these changes alone or will help come from an unexpected ally?


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Obama campaign toils in Iowa
By The Associated Press and Charles Babington |
DES MOINES, Iowa — One presidential campaign claims an impressive effort in Iowa this year: eight offices opened, 350,000 phone calls to potential supporters and 1,280 events to recruit and train volunteers.
It"s not Mitt Romney or Newt Gingrich or Ron Paul. It"s Obama for America, the president"s re-election campaign, which badly wants to win this battleground state in November, as it did in 2008.
"The Republicans are here today, gone tomorrow," said Obama volunteer Pat Walters, of Johnston, a suburb of Des Moines. "We"ve been doing this since 2009."
Next Tuesday"s Republican caucus has dominated political conversations. Largely overlooked is that Obama is running unopposed in the Democratic caucus the same night.
It"s a dramatically different scene from four years ago, when Obama set his course for the White House by beating John Edwards and Hillary Rodham Clinton after months of intense campaigning in Iowa.
Obama can coast as far as this year"s nomination is concerned. But Iowa remains a general election swing state, and no one assumes his 9-point win here over John McCain in 2008 will give him a cushion next November.
Obama"s campaign never entirely left Iowa or several other competitive states, where he hopes relentless organizing can overcome a weak economy and his mixed record of fulfilling campaign pledges in the face of strong GOP opposition in Congress. If thousands of volunteers flocked to Obama"s 2008 campaign, this time he"s having to work a bit harder to recruit and energize them.
"People say, "The mood is different this time, it"s not the same,"" said Peggy Whitworth, an Obama volunteer in Cedar Rapids. "Well of course it"s not the same. But it"s not about mood or feeling. It"s about the future of the country."
Whitworth, 69, said she joins other Obama volunteers four hours every Tuesday night, and sometimes on other evenings as well, to telephone potential supporters. Many say they will vote for Obama again, she said, and some volunteer to help the campaign. But some are disappointed or angry that the president fell short on campaign promises such as ending the Bush-era tax cuts for the wealthy, and bringing a greater spirit of bipartisanship to Washington.
"Sometimes they simply want to have someone listen to them," Whitworth said. Most say they will stick with Obama after they"ve had a chance to vent their frustrations, she said.
Obama lacks some key advantages he enjoyed in 2008. They include a deeply unpopular GOP president who was largely blamed for a faltering economy, and a widespread excitement about Obama"s precedent-breaking campaign built on "hope and change."
In exchange, of course, he has the power of the presidency and a well-oiled political organization that has been refining its practices for five years. Obama will raise many millions of dollars, although his eventual Republican opponent may do nearly as well.
Nowhere does Obama have a bigger base to build on than in Iowa, where he campaigned for months in 2007. Romney, Gingrich and other GOP contenders have not made comparable efforts, although they say the economy and other issues will make Obama"s task much harder next year.
In activities that rarely compete with the hoopla of the GOP nominating contest, Obama"s campaign has placed a handful of paid staffers in each of several key states. They try to leverage their clout by recruiting and training scores of volunteers. The volunteers, in turn, knock on doors, organize house parties and, above all, place phone calls to voters in hopes of identifying likely Obama supporters and tracking them through Election Day.
In a tortoise-versus-hare strategy, Obama supporters hope their steady chugging will build support precinct by precinct, town by town, while Republicans spend resources chasing the nomination for a few more weeks or months. The Republican candidates and their broadcast ads are flooding Iowa this week, but they will abruptly shift to New Hampshire on Jan. 4, the day after the caucuses.
Walters, a 60-year-old insurance executive, said he is a "neighborhood team leader" who helps organize house parties, phone banks and other activities. His chief recruiting tools, he said, involve reminding Iowans of Obama"s accomplishments that include expanding medical benefits in the hard-won 2010 overhaul of the nation"s health care system.
Walters said he hopes the week-by-week, month-by-month effort will build a strong ground operation to turn out Obama"s voters next November. The Republican nominee will have to play catch up, he said.
Obama"s ground game "is already in place," Walters said. "It"s just a matter of growing it."
Iowa Democratic Chairwoman Chair Sue Dvorsky underscored the methodical nature of the efforts in a conference call with reporters Wednesday.
Since April, she said, "this has been a systematic grassroots effort. The same exact way we did it last time. It isn"t very glamorous. It"s not a very secret plan. It is voter to voter, one-to-one, then a street, then a precinct, then a county."
Dvorsky said Obama will beam "a live address to Iowa Democrats in every caucus site next Tuesday night.
Charles Babington


Attorney General Eric Holder on Thursday said he will seek to require that the state of Texas clear all of its voting changes with the federal government, firing the opening salvo in a new battle over the Voting Rights Act.
"This is the department's first action to protect voting rights following the Shelby County decision, but it will not be our last," Holder said in Philadelphia, according to prepared remarks.
The Supreme Court last month ruled in Shelby County v. Holder that the voting law's requirement that states with a history of discrimination clear changes to their polling practices was unconstitutional, putting enforcement of the law in doubt.
Each and every American should have the right to vote, and with that should come some sort of guarantee that the state in which they live will not hinder that right in order to protect the political power of one party. Why we are not fighting for this is beyond comprehension. The right to vote should be granted to the people. Whether they vote or not is their business. An amendment to the Constitution that establishes the minimum standards for voting rights and access needs to codify and protect these rights.
There are too many games being played. Standardized voting for all citizens should be basic common sense at this point. The only reason why we don't have a standardized voting process is because people might vote against a Republican. That should tell you everything you need to know.


For your calendar, and as a reminder, we encourage you to attend the OBEA Conference on October 13-14. Immediately following, on October 15, we will be hosting an Adviser Academy from 8:30 to 2 p.m. at the Red Lion Pendleton.
We will provide light complimentary refreshments – there is no fee to participate in the Adviser Academy.
Click here for the information about the OBEA Conference again for your reference and click here for an OBEA Member Form. If you plan to attend the Adviser Academy – please RSVP by email.


Sometimes, tried-and-true methods are the way to go.
Terry Green said his secret to success, the key to raising thousands of dollars for the Alzheimer Society of Oxford, is sticking to what he's always done.
"I use telephone calls. Some people use emails, but I prefer the personal touch. I'm old-fashioned that way," he said with a smile.
It sure seems to be working for Green, who first got involved through his daughter, executive director Shelley Green. She remembers her dad doing laps at the very first Walk for Alzheimer's 23 years ago.
"Being exposed to Shelley, I see the need for people to be supported with this disease. I know the odd person who has dementia but I've not been personally exposed like a lot of people have," Green said.
Green said he understands the impact that Alzheimer Society programs have on families who are dealing with a dementia diagnosis.
"I know it's a great organization. I know they do so much for so many people, and are so well thought of in the community. Anyone who's had to avail themselves of their services, I think, would attest to that," he said.
And Green sees it as a privilege to be able to help keep those programs humming.


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A huge, iconic open air theatre in Regent's Park
Regent's Park Open Air Theatre | Al fresco culture in North London
Outdoor theatre always brings the house down.
And London's most iconic al fresco space, the Regent's Park Open Air Theatre, is back open for business this summer. The season kicks off with a critically acclaimed play set in a small American town, exploring simple, everyday life and what it means to be human. It won the Pulitzer Prize, and is famed for the simple quirk of having no sets.
After that, you can expect productions of Hansel & Gretel in collaboration with the English National Opera, then A Midsummer Night's Dream, and then a double-bill of musicals with Evita and Jesus Christ Superstar.
There's a bar on site, as well as a cafe, some covered dining, a grill, a pre-theatre drinks service, and picnics to buy on the spot.
And there's a picnicking lawn to eat them on too.
NOTE: Regent's Park Open Air Theatre takes place until September 21st. Tickets start at £23, and can be purchased at their website right HERE.
Regent's Park Open Air Theatre | Regent's Park, NW1 4NU
Like non-open air theatre? Find the best of that right here…
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Regent's Park Open Air Theatre
Regent's Park, Regent's Park, NW1 4NU
£££££
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This scheme comprises 6 x Vestas V44 turbines (600 kW each) with an installed capacity of 3.6 MW. It is owned and operated by Peel Energy and has been running since 1999 under a NFFO contract.


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Category: Nunavut
Iqaluit Grocery Store Fire Highlights Northern Food Security Issue
The recent grocery store fire in Iqaluit highlights the precarious nature of Northern food supplies.
A major fire this week that completely destroyed one of Iqaluit 's two grocery stores has reignited concerns about food insecurity in the North. Our thoughts go out to the entire population of Iqaluit at this difficult time. The blaze at the Northmart store not only destroyed the food on the shelves, but also an adjoining warehouse where a large cache of dry goods was being stored. Most of these goods, including stocks for Christmas and Easter, were brought in by barge while sea lanes were open during the summer, and now concerns have been raised about possible food shortages and escalating prices.
Food costs are already an issue throughout Nunavut, where 55 per cent of the population is living with food insecurity, according to Statistics Canada, and the issue has been getting worse since monitoring began in 2005. (StatsCan defines food insecurity as occurring when one or more household members do not have access to an acceptable amount of quality healthy food, usually because of financial constraints).
The entire issue of food security also falls across racial lines. A recent report found the average cost of groceries for a family of four in Nunavut is $19,760 per year while almost half of Inuit adults earn less than $20,000 annually. This is in contrast to annual salaries for the non-indigenous population averaging over $72,000 in Iqaluit.
It's worth thinking of the food security in your own community. No matter where you live, grocery stores only carry 3-4 days worth of perishable food. This is not such a big deal if one store shuts down in, say, Toronto, but in our current system your access to food is more fragile than you might imagine. If there is a disruption of the distribution chain (due to an internet black-out, for example, or natural disaster) food shortages could occur in a matter of days.
Supporting and enhancing local food systems in our own communities remains a critical piece in food security.
Seal Meat an Integral Part of Traditional Inuit Lifestyle
For many Inuit communities in the far North, especially fly-in communities not connected to the outside world by roads, food security is an ongoing concern.
While a number of new initiatives have been undertaken in recent years, including Nuluaq, The Inuit Community-Based Food Initiatives Mapping Project, one of the solutions is as old as the Inuit themselves — a return to country foods such as seal, walrus, whale, and fish harvested from the local environment.
Game meats are high in protein, fatty acids, vitamins and minerals. Seal meat is especially lean with less than two per cent fat (compared to 12 to 27 per cent fat in other store-bought meats). It's also rich in iron, zinc, vitamins A, D, B and C, and Omega 3 fatty acids. Through initiatives like community kitchens and cooking classes, hunter coops, and communal freezers, efforts are being made to help far Northern communities expand local access to country foods. Southerners are discovering seal meat too, and some chefs, indigenous and non-indigenous alike, are bravely adding the dish to their menus, including Chef Eric Pateman's Edible Canada in Vancouver, and chef Joseph Shawana's Toronto restaurant, Kū-Kŭm Kitchen.
The move can be a controversial one, because the harvesting of seals continues to be a touchy topic for some animal rights activists. For several decades opposition to seal products by global animal rights groups has impacted the ability of Inuit communities to sell their seal products. Seal skin products used for waterproof, biodegradable clothing such as boots, mittens and hats, have long been a vital source of cash to purchase items such as the boats/snowmobiles, gasoline, and ammunition used by hunters.
The Inuit are fighting to change public opinion. Most notably, Iqaluit film maker Alethea Arnaquq-Baril, director of the documentary Angry Inuk, has started to alter outisder perceptions. The Canadian government is also trying to get the message across that the harvest is humane and sustainable. But for many northern Canadians it's much more basic. They simply consider seal comfort food.
Nunavut's The Laughing Chef Promotes Local Food in the North
Rebecca Veevee, Nunavut's The Laughing Chef. Photo by permission, Rebecca Veevee
Inuk chef and cooking show host Ooleepeeka (Rebecca) Veevee, The Laughing Chef, is a familiar and beloved face in Nunavut. Armed with her ulu, her infectious smile and her sense of humour, Ooleepeeka is the driving force behind the Inuit Broadcasting Company's popular TV show "Niqitsiat" (which means "Good Food Ideas") – a cooking show that profiles Northern dishes made with traditional Inuit food from the land or "country food".
Caribou pizza, goose soup, char casserole, seal pie, beluga muktuk stir-fry are just some of the dishes that Ooleepeeka Veevee cooks up on her show. Ooleepeeka often brings guests on her show including NHL hockey star Jordin Tootoo (first Inuk to play in the NHL). No one is too famous to learn from Ooleepeeka!
In 2015 Ooleepeeka Veevee received the Governor General's Meritorious Service Award for her work promoting traditional Inuit foods. In awarding her the honour, the government cited how her TV program has been recognized for combating a growing epidemic of diseases related to poor nutrition in northern communities.
Ooleepeeka has shared her variation of a Traditional Seal Meat Recipe (link) with First We Eat.
"Niqitsiat" has been broadcast in Inuktitut on the Inuit Broadcasting Company since 2009 and can be viewed on APTN . Check out an episode of Niqitsiat, Ooleepeeka Veevee teaching how to cook BBQ arctic char and caribou head.
> Click here for Ooleepeeka Veevee's Traditional Seal Meat Recipe
Seal Hunt is Foundation of Traditional Lifestyle
Angry Inuk by Inuk filmmaker Alethea Arnaquq-Baril documents the economic, social, and cultural devastation caused by decades of anti-sealing activism.
For the Inuit communities of Nunavut, seal meat has been a staple in their local diets for millennia. The meat is a vital source of fat, protein, vitamin A, vitamin B12, and iron. Seal pelts are also prized for their warmth, and since first contact with Europeans, trade in seal products has played an important role in the regional economy. This revenue is especially crucial in remote areas where many foodstuffs need to be imported, and transportation costs are high.
A commercial seal hunt in Southern Canada, most notably the annual spring hunt in the Gulf of Saint Lawrence, has generated controversy in recent decades, led by high-profile animal-rights activists, and resulting in a 2006 call by the European Union for a ban on all harp seal and hooded seal products. The traditional Inuit seal hunt has been swept up in an animal rights activism fervor, adversely affecting an age-old way of life.
But now indigenous groups are standing up for their heritage and defending their traditional lifestyles. Inuit filmmaker Alethea Arnaquq-Baril has released Angry Inuk, a feature-length documentary that defends the Inuit seal hunt. In Toronto, Indigenous chef Joseph Shawana is keeping seal meat on the menu at his Ku-Kum Kitchen restaurant, despite a petition calling for its removal, and is galvanizing a groundswell of public support of his own.
Partially shot in the filmmaker's home community of Iqaluit, as well as Kimmirut and Pangnirtung, where seal hunting is seen as essential for survival, Angry Inuk also follows an Inuit delegation to Europe in an effort to have the EU Ban on Seal Products overturned. The film criticizes NGOs such as Greenpeace and the International Fund for Animal Welfare for championing animal rights while ignoring the needs of vulnerable northern communities who depend on the hunt for their livelihoods.
Chef Shawana, whose restaurant specializes in indigenous-themed dishes, says he researched the Northern hunt before opting to serve seal meat. He points out the Inuit seal harvest is very sustainable and humane, and contrasts it with the roughly two million cows, 20 million pigs, and 550 million chickens killed each year in Canada alone during large-scale food production. But at the root of the issue, says Shawana, is the need to acknowledge and support Canada's aboriginal cultures.
Seal tartare is just one of many indigenous-themed dishes served at Ku-Kum Kitchen by owner/chef Joseph Shawana.
Posted on March 5, 2017 July 16, 2017
Marinated Maktaaq Salad from Arviat, Nunavut
Marinated maktaaq salad, by Arviat Wellness Centre
A new addition to our tips and recipes page, the Marinated Maktaaq Salad from Arviat, Nunavut, makes use of local maktaaq and wild flowers.
Continue reading "Marinated Maktaaq Salad from Arviat, Nunavut"
Local Fertilizer in Arviat, Nunavut
When you live in a fly-in community in the North, shipping by plane can be very expensive, especially for heavy items such as soil and fertilizer.
The people behind the community greenhouse in Arviat, Nunavut, have taken on the very important issue of food security by devising a strategy to grow their own produce.
And one of the biggest obstacles they have found is that the local soil lacks nutrients. Commercial soil works fine, but it is costly and it needs to be flown in, which impacts the sustainability of the project.
Arviat's Greenhouse, Photo by Arviat Goes Green
Continue reading "Local Fertilizer in Arviat, Nunavut"
Arviat Goes Green
Many northern Canadian communities do not have the luxury of the rich soil found in southern Yukon. This is the case for the fly-in community of Arviat, (population 2,800) – the second largest community in Nunavut.
Arviat Map, Nunavut, Canada
In 2014 Arviat built a greenhouse beside the school to see if they could grow their own vegetables with local soil and local fertilizer. And they have been very successful!
Continue reading "Arviat Goes Green"


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Singer and Actress Sulli Passes Away Aged 25
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'Downton Abbey' star Jim Carter to perform in a pair of local fundraisers
By Jody FeinbergThe Patriot Ledger
As Carson, Carter is known for his upright formality, so "Downton Abbey" fans likely will be delighted to see him perform magic tricks and tell stories at benefits in Somerville and Arlington this weekend.
Forty years before Jim Carter played the butler Carson on "Downton Abbey," he went to circus school in New York, where he juggled, walked a tightrope and did magic tricks.
"I can still juggle a bit, but tight rope has probably passed me by – it would have to be a bloody big rope," Carter, who is a hefty 6-foot, 2-inches, said jokingly.
As Carson on the popular PBS period drama, Carter is known for his upright formality rather than his humor or playfulness, so "Downton Abbey" fans likely will be delighted to see him perform magic tricks and tell stories at benefits in Somerville and Arlington this weekend.
"Hopefully, people will be pleasantly surprised at the difference between me and Carson," said Carter, speaking in an interview from his London home in his unmistakably deep, dignified voice.
The "Downton Abbey" series tells the story of the aristocratic Crawley family and their servants. The show is set in Highclere Castle, England, beginning in the years leading up to World War I. With the sixth and final season of "Downton Abbey" underway, Carter is turning his energy toward raising awareness about WandAid, a charity he started last summer with Liz Turnbridge, producer of "Downton Abbey," and Linda Cruse, a humanitarian aid worker.
"This is the first week I would have been back filming and it's when you realize, 'Oh, God, I'm not doing that," said Carter, 67, who received two Screen Actors Guild Awards and nominations for four Emmy Awards. "I think it's right to end it before people feel the story has run out. And it's natural in our lives (as actors) to move onto different things. The show has given me the kind of profile that allows me to turn it into something good, to give back at my stage in life."
In the coming months, Carter will travel with WandAid to Nepal, whose residents remain in dire need after the devastating earthquake last April. At the performance this weekend to benefit earthquake victims, Cruse will talk about WandAid's mission to use magic, circus arts and other entertainment to bring joy and hope. The program also features Lesley Smith, a ventriloquist, entertainer and singer/songwriter.
"We use laughter to make people smile, laughter being the first step toward psychological recovery when there has been trauma," Carter said. "Entertaining people is the easiest way to connect with them and start a conversation."
The benefit shows on Friday and Saturday also are intended to create conversations between Carter and "Downton Abbey" fans.
"I'll answer any questions that aren't vulgar," he said, joking. "I'm hoping people will come armed with them."
Carter said the enormous popularity of the series has been gratifying, but a little unsettling.
"This has come late in my career, and it's the biggest thing I, or any of us, will ever be in," said Carter, who has been seen by more than 120 million viewers worldwide. "After 45 years, being recognized is strange, and with my face and size, I'm quite recognizable. People know me instantly."
Of course, what they know is Carson – described by Carter as very traditional, morally upright and proud of his skills and the respect he receives, yet at times pompous and a bit ridiculous.
"In my private life, I'm nothing like him," said Carter, an avid cyclist who has done charity rides around the world. "I'm not a creature of routine and I couldn't abide a stuffy house like that ... but I do believe in good manners and being polite and punctual."
Part of what made the role interesting for Carter is that Carson is a connection between the upstairs world of the aristocratic Crawleys and the downstairs world of the servants.
"It's interesting to play because I floated between the two and saw everything," he said. "It emerged as we went on with the series that I was the moral compass of the house, the touchstone really." And since Carson is "so buttoned up and there's so much that he can't say," Carter said "there's a delight" in using facial expressions and body language to convey layers of meaning.
As the series spans 1912 to 1925, it's moving to see Carson deal with a new order.
"Everything would stay in 1898 if Carson had his way, Carter said. "Poor old Carson, he has to deal with everything changing really fast, and slowly in his own way, he does. In one of the episodes this season, there's a scene where I leave the cell-like bedroom where I have spent my life for the last time. My world will never be the same, and it's very poignant."
Carter, who has appeared in more than 40 films and dozens of television series, said he thinks that the show's huge appeal to Americans is multi-faceted. Beyond the production values and talented acting, there is the appeal of being transported to a foreign and comparatively simpler world.
"We're dealing with a class system and structure of manners that didn't exist in America and it seems slightly bizarre and exotic," he said. "'Downton Abbey' harkens back to a world that seems to be more secure. And one of the challenges of the modern world is that there are so many choices and people are insecure about what they should do." In at least one aspect of his life, Carter is connected with century-old English traditions. In West Hempstead where he lives with his wife, actress, Imelda Staunton, he often can be found at the 150-year-old Hampstead Cricket Club, where he has been chairman for six years and organizes leagues for men, women and children.
"Every time I had a break from 'Downton,' I'd be down there," Carter said. "It's the quintessential English game."
Jody Feinberg may be reached at jfeinberg@ledger.com or follow on Twitter @JodyF_Ledger.
IF YOU GO . . . .
WHAT: "Downton Abbey's" Jim Carter hosts the Nepal Fundraiser
WHERE: Somerville Theatre, 55 Davis Square, Somerville.
TICKETS: $35 adults and $25 students and children.
INFO: somervilletheatre.com
WHAT: An Evening with Jim Carter
WHEN: 7 p.m. Sunday
WHERE: Regent Theatre, 7 Medford St., Arlington.
TICKETS: $45. V.I.P. tickets $75 including a meet and greet reception with Jim Cage and Linda Cruse from 5:30 to 6:30 p.m.
INFO: regenttheatre.com
INFO on WandAid: wandaid.org


Different transfusion ratio concepts of packed red blood cells (pRBCs), fresh frozen plasma (FFP) and platelets (PLTs) have been implemented in trauma care, but the optimal ratios are still discussed. In this study the hemostatic potential of two predefined ratios was assessed by using an in vitro thrombelastometric approach. Furthermore, age effects of reconstituted blood were analyzed.
Whole blood (WB) of voluntary donors was separated into pRBCs, FFP and PLTs and reconstituted into the ratios 1:1:1 and 3:1:1 at day 1, 4, 14, and 24. Standard blood count, electrolytes and coagulation proteins were quantified. The functional coagulation in ratio- and age-specific groups was evaluated using rotational thromboelastometry (ROTEM).
Several coagulation factors reduced significantly in the 3:1:1 ratio and were consistent with increased INR, decelerated clot formation times and A10 (amplitude 10 minutes after clotting time (CT)), flattened α-angle during the EXTEM and diminished MCF for distinct time points during the INTEM, FIBTEM and APTEM assays. With rising age of pRBCs the pH, sodium and potassium reached non-physiological levels.
Under standardized in vitro conditions the higher amount of pRBCs in the 3:1:1 ratio diluted coagulation factors significantly on the expense of its functional coagulation capacity as revealed by ROTEM results. Thus, the coagulation functionality of the 1:1:1 ratio predominated.
As there is less doubt about the components to be administered during transfusion the evidence for an appropriate transfusion ratio is still lacking . Different ratios of pRBCs, FFP and PLTs are applied in clinical practice [2-4] at which the 1:1:1 ratio has been adopted by trauma centers worldwide for the acute treatment of bleeding trauma patients [5,6]. For massive transfusion the use of a RBC:FFP ratio of 1:1 or 2:1 was recommended based on systematic reviews [7-11] and a reduction of death risk for trauma patients was associated when transfused in the range of 1:1 to 2.5:1. Currently, the PROPPR study as a phase III prospective randomized trial was conducted by several trauma centers in the United States that targets the efficacy of the transfusion ratio 1:1:1 compared to 2:1:1 (pRBCs:FFP:PLTs) within a massive transfusion (MT). Overall limited evidence due to retrospective or unfinished prospective designs  and numerous potential confounders [1,10,13-16] as well as poor compliance to MT protocols (MTP) during resuscitation limits the expressiveness and results of these studies.
Besides transfusion ratios the application of blood products stored less than two weeks (fresh blood) or more than 14 days (old blood) is also crucially discussed. Previously, lower postoperative complications and increased long-term survival were observed after cardiac surgery when transfusing fresh compared to older blood [17,18]. A higher mortality rate and severity of transfusion related acute lung injury (TRALI) was shown after administering stored pRBC in different animal studies [18,19] with comparable results in additional studies [20-24]. Furthermore the erythrocyte cell membrane deformability irreversibly decreased with storage duration and might be responsible for reduced oxygen transport [24-29].
The present study addressed the question of a predominance of the ratios 1:1:1 and 3:1:1 of pRBCs, FFP and PLTs in contrast to whole blood on the one hand and age-specificities of fresh and old blood on the other. For this purpose, they were compared in vitro under standardized conditions by measuring electrolytes, blood and coagulation proteins as well as analyzing functionality of coagulation and at distinct time points.
After institutional review board approval and written informed consent a volume of 450 ml type A blood of six voluntary donors was collected in standard bags supplemented with 63 ml of CPD (citrate, phosphate, dextrose) stabilization solution. Initially, the blood was stored for 20 hours at validated CompoCool plates (Fresenius Kabi, Bad Homburg, Germany) prior to leukocyte-depletion (by filtering) and separation (by centrifugation) into pRBCs, FFP and PLTs. The pRBC of 260 ± 50 ml volume contained 100 ml of SAG-M (adenine, glucose and mannitol) solution and were stored at 4°C ± 2°C until usage. FFP was portioned in 250 ± 30 ml bags, shock-frozen and stored at −30°C. Due to the short storage life a maximum four days old PLTs bag of 260 ± 40 ml was used that had been incubated under constant agitation at 22°C ± 2°C.
Since the volume of the blood product bags differed, the pRBCs, FFPs and PLTs were weighted first before calculating its percentage of volume prior reconstitution which allowed a realistic transfusion procedure of the ratios 1:1:1 and 3:1:1 to a final volume of 50 ml. All measurements were performed at day one, four, 14, and 24. Additionally, whole blood was measured at day one. The detailed proceeding was represented in Figure 1.
Procedure of blood separation and reconstitution as well as subsequent experiments.
All measurements were performed at the Institute of Transfusion Medicine, Cologne-Merheim Medical Centre. The standard hemogram (Full Blood Count, FBC) parameters erythrocytes, leucocytes, platelets, hemoglobin, hematocrit, mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and red blood cell distribution width (RDW) were measured on the Cell-Dyn 1700 Hematology Analyzer (Abbott Laboratories, Abbott Park, USA). International normalized ratio (INR), partial thromboplastin time (PTT), fibrinogen, antithrombin, the factors II, V, VII, VIII, IX, X, XI, XII, and VIII, protein C, protein S, d-dimer, vonWillebrand factor activity (vWF:a), and vonWillebrand factor Antigen (vWF:Ag) were quantified following the manufacturer's manuals (Instrumentation Laboratory Company; Bedford, USA; Siemens Healthcare Diagnostics Products GmbH, Marburg, Germany) by using the ACL TOP system (Instrumentation Laboratory Company; Bedford, USA) and the APACT 4S Plus (Rolf Greiner BioChemica, Flacht, Germany).
The values of sodium, potassium, calcium, and the pH were determined by blood gas analysis via the IRMA TruPoint Blood Analysis System (Keller Medical GmbH, Bad Soden, Germany).
Kinetics of hemostasis was followed by ROTEM delta analysis in accordance to the manufacturer's instructions (Tem International GmbH, Munich, Germany) (Figure 2). The 30 minutes thromboelastometric measurement included the extrinsically activated assay with tissue factor (EXTEM), the intrinsically activated test using ellagic acid (INTEM), the extrinsically activated test with tissue factor and the platelet inhibitor cytochalasin D (FIBTEM) as well as the extrinsically activated assay after blocking hyperfibrinolysis by aprotinin (APTEM). The parameters clotting time (CT), clot formation time (CFT), α-angle, amplitude 10 minutes after CT (A10), and maximal clot firmness (MCF) were analyzed for the EXTEM, INTEM and APTEM assays while the CFT was not determined for FIBTEM.
Kinetics of hemostasis as demonstrated by a viscoelastic test (ROTEM, Tem Innovations GmbH).
Collected data were analyzed by the nonparametric Kruskal-Wallis test to assess the effects of time and ratio in the different time-by-ratio groups using the IBM SPSS Statistics, version 21.0 (Armonk, NY, USA). P values were corrected in the subsequent pairwise comparison of groups. Differences were considered statistically significant at p < 0.05.
The cumulative comparison of coagulation factor activity was performed by calculating the overall mean of all factors for the WB, 1:1:1 and 3:1:1 group, respectively.
Irrespective of blood product age, several measured parameters differed between the ratios 1:1:1 and 3:1:1 (Table 1). The quantity of erythrocytes was significantly lower in the 1:1:1 group compared to WB. Platelets were elevated in the 1:1:1 ratio at all points in time and differed significantly from the corresponding levels of the whole blood. Leucocyte depletion of the original blood samples resulted in a drastically decline in both ratios (<500/μl). While hemoglobin and hematocrit levels of the 3:1:1 ratio and the WB were likewise, the 1:1:1 ratio had significantly reduced levels in comparison with both groups at the reviewed time points. Overall, age-specific differences were not observed for erythrocytes, platelets, hemoglobin, and hematocrit. Similarly, MCV, MCH and RDW remained constant and were not affected by age or ratio.
Values are represented as mean ± standard deviation. Differences (p < 0.05) are marked as + when comparing with whole blood (WB) and as *to compare both ratios irrespective of time point.
Only few age effects could be observed (Table 2) and thereof most notably the values of potassium and sodium. Independent of ratio potassium increased progressively over time being 2.4- and 4.6-fold higher after 24 days in the 1:1:1 and 3:1:1 ratio, respectively. In contrast, sodium reduced with increasing age and differed significantly in both ratios between day one and 24. The environment of the reconstituted blood slightly acidified as in both ratios the pH value decreased with age and was reduced stronger in the 3:1:1 group from day four (Table 2). No alteration of calcium was determined during the measurement.
Values are represented as mean ± standard deviation. Lowercases indicate significant differences (p < 0.05) between: a - day 1 and 4, b - day 1 and 14, c - day 1 and 24, d - day 4 and 14, e - day 4 and 24, and f - day 14 and 24, respectively.
For almost all coagulation factors ratio-specific reductions in the 3:1:1 group were observed at any time point when comparing both ratios (Table 1). The factors VII, IX, X and XII were constantly and significantly reduced in 3:1:1 samples, independent of age while the factors II, V, and XIII significantly declined not before day four. Similar to the blood count parameter the quantity of coagulation factors was affected minor by age (Table 2). Although several factors tended to be reduced after 24 days only the factors II, V and VII measured in the 1:1:1 ratio and factors IX, XI and XIII in the 3:1:1 group reached the level of significance. The cumulative factors were comparable in the WB and 1:1:1 group whereas a precise decline was observed when comparing both groups to the 3:1:1 ratio at day 1 or when comparing the 1:1:1 with the 3:1:1 ratio at the respective time points (Figure 3).
Quantitative cumulative factor quantity (summing up coagulation factors FII, FV, FVII, FVIII, F IX, FX, FXI, FXII, FXIII) and INR of the WB, 1:1:1 and 3:1:1 groups. Levels are represented as mean and standard deviation. Bars are depicted as dotted (WB), light grey (1:1:1) and dark grey (3:1:1). Significances were observed at *p < 0.05; **p < 0.01; ***p < 0.001.
The activity of the coagulation inhibitors antithrombin and protein C as well as its cofactor protein S were significantly lowered in the 3:1:1 compared to WB (day one) and in most cases considerably reduced in 1:1:1 ratio at all ages (Table 2). Fibrinogen was also diluted in 3:1:1 samples from day four on (Table 1).
Consistent with the reduction of coagulation proteins in the 3:1:1 ratio an elevated PTT and INR were observed in the 1:1:1 group irrespective of age. Both values reached significant levels with the exception of PTT at day one (Table 1). Furthermore, the INR trended to increase with age in both ratios. A declined functionality of the extrinsic and intrinsic system was also measured by ROTEM analysis. The CFT significantly decelerated at almost all time points in the 3:1:1 group of the EXTEM approach (Table 1). Similarly, CTs were prolonged by trend in the 3:1:1 group, however, not reaching significant level. Also the α-angle and the clot amplitudes after 10 and 30 minutes declined in the 3:1:1 ratio at day one, four and 14 (Figure 4).
Functional characterization of coagulation via ROTEM analysis. The α-angle, amplitude after 10 minutes (A10) and maximum clot firmness (MCF) after 30 minutes of the EXTEM, INTEM, FIBTEM, and APTEM assays are represented as mean and standard deviation. Bars are depicted as dotted (WB), light grey (1:1:1) and dark grey (3:1:1). Significances were observed at *p < 0.05; **p < 0.01; ***p < 0.001. Age differences (p < 0.05) were indicated with the lowercases a (day 1 ↔ 4), b (day 1 ↔ 14), c (day 1 ↔ 24), d (day 4 ↔ 14), e (day 4 ↔ 24), and f (day 14 ↔ 24), respectively.
For the INTEM, FIBTEM and APTEM assays the main difference were observed after four and 14 days (Table 1, Figure 4). Thereafter mostly tendencies were determined due to a high variation within the groups. However, the MCF seemed to be the most consistent value in these three approaches providing significant declines in the 3:1:1 ratio irrespective of the activation pathway. As observed for other measured values the age differences were inconsistent and being present for few comparisons of EXTEM α-angle as well as for INTEM and FIBTEM CTs (Table 2).
Over 10 years ago the correlation of transfusion practices and patients' outcome was stronger focused in trauma research. Several publications [2,10,11,30] underlined the superiority for using defined ratios of pRBCs and FFPs solely or combined with PLTs. Due to heterogeneity such as patients' inclusion criteria (if they were even defined) and in the applied ratios (1:1; 2:1, 3:1 etc.) the evidence of these studies was limited. In 2007, Borgman et al.  firstly presented a systematic analysis of trauma care including a transfusion ratio concept that increased the survival rate in major bleeding patients. This study still represents the unproven guideline in handling these kinds of seriously injured patients. Currently, the multicenter PROPPR study systematically compared the transfusion ratios 1:1:1 and 2:1:1 (pRBCs:FFP:PLTs) in a clinical trial and brought first (but final) evidence in the discussion regarding transfusion ratios .
In this in vitro study the physiological characteristics of the 3:1:1 ratio go along with a reduction of all coagulation factors resulting in a lowered hemostasiological potential that was indicated by elevated INR and viscoelastic tests. The thrombelastometric findings (ROTEM) in dilution effects in the 3:1:1 ratio became evident by a decreased dynamic clot formation and clot quality as indicated by a flattened α-angle and a lowered clot firmness after 10 and 30 minutes (A10, MCF). Furthermore, a trend of decelerated clot formation could be observed.
There was no evidence that the processing of plasma (freezing, storage, thawing) may explain the changes in factor quantity and viscoelastic functionality of the 3:1:1 group, since 10 days of storage and subsequent thawing did not affect coagulation factors as shown previously . In addition, this proceeding effect would have been observed in the 1:1:1 ratio as well. To ensure the allocation of functional factors in FFPs and to further minimize influencing effects on coagulation, maximum 4 days old factor-rich plasma was used at any time point before reconstitution. Thus, the lower quantity of coagulation factors whether significantly reduced in the 3:1:1 ratio or trend to be decreased can rather be explained by diluting effects than by inactivation of factors. Furthermore, cumulative factors were comparable between WB and 1:1:1 providing an adequate initial basis for coagulation [30,33]. In summary the hemostasiological potential of the 1:1:1 ratio rather referred to that of WB. Transfusion ratios leading to a nearly physiological hemostasiological potential and an effective coagulation may reduce the amount of pRBCs being transfused. According to the current European guideline  transfusion of pRBC is recommended in patients with Hb values below 7 mg/dl.
The findings of the present study were in line with results of a recently published in vitro study in which a dilution effect in a 3:1 (pRBC:FFP) ratio was determined by simulating postpartum hemodilutional coagulopathy . Therefore, there seemed to be a superiority of the 1:1 ratio of pRBC and FFP transfusion optimized by an additional application of the same ratio of PLTs. Interestingly, no dilution effect due to FFP was observed though not only concentrates of clotting factors were used. Similar results were reported for a thrombelastography (TEG) approach in which different ratios of pRBC:FFP:PTL were analyzed in vitro. In line with the results of the present study, a higher proportion of pRBCs such as 8:4:1 of pRBC:FFP:PTLs resulted in decreased abilities to form a stable clot (reduced angle and maximal amplitude) .
This in vitro experiment enabled the assessment of quantitative and functional coagulation under standardized environments and revealed main findings in dilution and associated effects on functional coagulation. However, interrelated physiological impact on TIC like hypothermia, acidosis, inflammation, shock or the preliminary treatments such as pre-hospital volume administration [37-39] and therefore, dilution and hyperpermeability, shedding of the endothelial glycocalyx with autoheparinization  and activation of the protein C pathway [41,42] influence its coagulation potency. Disease pattern leading to major bleeding are very individual. Therefore, we could only propose a possible influence of the applied ratio of blood products in human. Efficient therapy of coagulopathy reduces significantly morbidity and mortality in trauma patients [2,43]. Independent from (surgical) therapies, coagulopathy is recognized as independent disease with an individual need for therapy nowadays [44,45].
Addressing the question if there are differences in newer compared to older blood trends of reduced corpuscular components after 24 days were shown. Inverse the highest potassium and lowest pH value were measured at day 24 which might be explained by an increasing erythrocytes degradation . With regard to clinical practice one should consider that potassium levels higher than 8 mmol/l have to be taken into further account when applying the 3:1:1 ratio. As demonstrated in previous clinical studies [27-29,47,48] in which the length of storage of pRBC influenced hemolysis, changes in deformability as well as osmotic fragility the results of this study did not reveal any continuous age effect according to the hemostasiological potential. However, the changes of potassium (13.01 ± 0.15 mM), sodium (136.72 ± 1.67 mM) and pH levels (6.69 ± 0.06) associated with aging blood products cannot be disregarded when applying to patients after 24 days of storage.
Regarding clotting time and clot formation a continuous but not significant increase was detected for INTEM while FIBTEM values reacted vice versa.
This systematic in vitro study offers valuable information about transfusion ratios as well as influencing age effects on coagulation. With regard to limitations of in vitro trials, the presented results suggest a superiority of 1:1:1 ratio in a physiological setting in case of transfusion encouraging higher use of plasma rather than pRBCs. Thus, dosage, ratio and administration of blood components still remain a dichotomy between benefits and harms whereby this study highlighted the need for multi-center clinical trials to determine the optimal transfusion strategy.
The higher proportion of pRBCs of the 3:1:1 ratio resulted in dilution properties of almost all coagulation factors and inhibitors.
Dilution likewise affected the hemostasiological potential which was indicated by an elevated PTT and INR in the 3:1:1 compared to 1:1:1 group.
The reduced functional coagulation of the 3:1:1 ratio was further specified by a decelerated CFT, flattened α-angle and diminished MCF of the ROTEM analysis.
Arne Driessen and Nadine Schäfer equal contributors.
We kindly thank M. Lassonczyk and A. Camphausen for technical support.
AD and NS contributed to study conception and study design, collection of data, interpretation and preparation of the manuscript. ES and MM contributed to study conception and study design, analysis and interpretation of data and revision of the manuscript. UB, SK and CFD contributed to study design and revision of the article. All authors have read and approved the manuscript for publication.


University of Chicago's K.T. Jerry Yeo will discuss pioneering collaboration on getting patients the right medication at the right dosage and at the right time.
AACC's first-ever virtual meeting will have a high-tech focus, drawing laboratorians who work in proteomics, metabolomics, and pharmacogenetics. One of the top presentations during the meeting will provide an update on a new genotyping project with a unique perspective.
KT Jerry Yeo, PhD, DABCC, FACB, director of clinical chemistry, pharmacogenomics, and translational mass spectrometry laboratories at the University of Chicago Medical Center, will discuss UChicago's 1200 Patients Project. This pioneering research effort is exploring how a person's genetic makeup can help his or her physician make decisions about medicines. Based at the Center for Personalized Therapeutics, it is the first large-scale clinical trial providing broad genetic information to be used for routine treatment decisions.
Yeo will preface discussion of the 1200 Patients Project with an examination of current barriers in using pharmacogenomics in patient care. The field lacks data from large randomized controlled trials, and many institutions do not have in-house expertise for consultations and interpretations. At the same time, labs face challenges in determining which analytical platforms to use for pharmacogenomics testing. Clinicians and laboratorians also need a better understanding of the utility and limitations of pharmacogenomic panels and the role of nongenetic influences on test results.