text:
Investigating the impact human protein–protein interaction networks have on disease-gene analysis
Fiona Browne, Haiying / HY Wang, Huiru Zheng
Advances in high-throughput technologies along with the curation of small-scale experiments has aided in the construction of reference maps of the interactome. These maps are critical to our understanding of genotype-phenotype relationships and disease. However, our knowledge of disease associated genes and the map of the human interactome still remains incomplete. In this study we investigate whether protein–protein interaction networks (PPINs) constructed from either experimental or curated data have an impact upon disease network analysis. An integrative network-driven framework is implemented to integrate diverse heterogeneous data including: gene-expression, PPIN, ontology-based similarity, degree connectivity and betweenness centrality measures to uncover potential Alzhemier disease (AD) candidate genes. Two PPINs have been selected and constructed from (1) experimental high-throughput data and (2) literature-curated sources. Only a marginal overlap of protein pairs between the two PPINs (305 protein pairs) was observed. A total of 17 significant AD gene candidate genes were identified using the literature derived PPIN compared to 20 genes using the PPIN constructed from high-throughput data. Both approaches correctly identified the AD susceptible TRAF1, a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death. Biological process enrichment analysis revealed genes candidates from the literature based PPIN are modulated in AD pathogenesis such as neuron differentiation and involved in KEGG pathways such as neurotrophin signaling pathways. Tissue specific analysis revealed 48 % of AD gene candidates obtained from the literature curated PPIN were expressed in tissues where AD is observed compared to 19 % of gene candidates extracted using the high-throughput PPIN.
International Journal of Machine Learning and Cybernetics
protein interaction networks
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Dive into the research topics of 'Investigating the impact human protein–protein interaction networks have on disease-gene analysis'. Together they form a unique fingerprint.
Genes Engineering & Materials Science 100%
Throughput Engineering & Materials Science 32%
Nerve Growth Factors Engineering & Materials Science 24%
Proteins Engineering & Materials Science 21%
Tissue Engineering & Materials Science 19%
Gene expression Engineering & Materials Science 12%
Electric network analysis Engineering & Materials Science 11%
Neurons Engineering & Materials Science 10%
Browne, F., Wang, H. . HY., & Zheng, H. (2018). Investigating the impact human protein–protein interaction networks have on disease-gene analysis. International Journal of Machine Learning and Cybernetics, 9(3), 455-464. https://doi.org/10.1007/s13042-016-0503-5
Browne, Fiona ; Wang, Haiying / HY ; Zheng, Huiru. / Investigating the impact human protein–protein interaction networks have on disease-gene analysis. In: International Journal of Machine Learning and Cybernetics. 2018 ; Vol. 9, No. 3. pp. 455-464.
@article{64c39ba771174543bc60feb0917c8cbe,
title = "Investigating the impact human protein–protein interaction networks have on disease-gene analysis",
abstract = "Advances in high-throughput technologies along with the curation of small-scale experiments has aided in the construction of reference maps of the interactome. These maps are critical to our understanding of genotype-phenotype relationships and disease. However, our knowledge of disease associated genes and the map of the human interactome still remains incomplete. In this study we investigate whether protein–protein interaction networks (PPINs) constructed from either experimental or curated data have an impact upon disease network analysis. An integrative network-driven framework is implemented to integrate diverse heterogeneous data including: gene-expression, PPIN, ontology-based similarity, degree connectivity and betweenness centrality measures to uncover potential Alzhemier disease (AD) candidate genes. Two PPINs have been selected and constructed from (1) experimental high-throughput data and (2) literature-curated sources. Only a marginal overlap of protein pairs between the two PPINs (305 protein pairs) was observed. A total of 17 significant AD gene candidate genes were identified using the literature derived PPIN compared to 20 genes using the PPIN constructed from high-throughput data. Both approaches correctly identified the AD susceptible TRAF1, a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death. Biological process enrichment analysis revealed genes candidates from the literature based PPIN are modulated in AD pathogenesis such as neuron differentiation and involved in KEGG pathways such as neurotrophin signaling pathways. Tissue specific analysis revealed 48 % of AD gene candidates obtained from the literature curated PPIN were expressed in tissues where AD is observed compared to 19 % of gene candidates extracted using the high-throughput PPIN.",
keywords = "network analysis, data integration, protein interaction networks, Alzheimer's Disease",
author = "Fiona Browne and Wang, {Haiying / HY} and Huiru Zheng",
journal = "International Journal of Machine Learning and Cybernetics",
Browne, F, Wang, HHY & Zheng, H 2018, 'Investigating the impact human protein–protein interaction networks have on disease-gene analysis', International Journal of Machine Learning and Cybernetics, vol. 9, no. 3, pp. 455-464. https://doi.org/10.1007/s13042-016-0503-5
Investigating the impact human protein–protein interaction networks have on disease-gene analysis. / Browne, Fiona; Wang, Haiying / HY; Zheng, Huiru.
In: International Journal of Machine Learning and Cybernetics, Vol. 9, No. 3, 03.2018, p. 455-464.
T1 - Investigating the impact human protein–protein interaction networks have on disease-gene analysis
AU - Browne, Fiona
AU - Wang, Haiying / HY
AU - Zheng, Huiru
N2 - Advances in high-throughput technologies along with the curation of small-scale experiments has aided in the construction of reference maps of the interactome. These maps are critical to our understanding of genotype-phenotype relationships and disease. However, our knowledge of disease associated genes and the map of the human interactome still remains incomplete. In this study we investigate whether protein–protein interaction networks (PPINs) constructed from either experimental or curated data have an impact upon disease network analysis. An integrative network-driven framework is implemented to integrate diverse heterogeneous data including: gene-expression, PPIN, ontology-based similarity, degree connectivity and betweenness centrality measures to uncover potential Alzhemier disease (AD) candidate genes. Two PPINs have been selected and constructed from (1) experimental high-throughput data and (2) literature-curated sources. Only a marginal overlap of protein pairs between the two PPINs (305 protein pairs) was observed. A total of 17 significant AD gene candidate genes were identified using the literature derived PPIN compared to 20 genes using the PPIN constructed from high-throughput data. Both approaches correctly identified the AD susceptible TRAF1, a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death. Biological process enrichment analysis revealed genes candidates from the literature based PPIN are modulated in AD pathogenesis such as neuron differentiation and involved in KEGG pathways such as neurotrophin signaling pathways. Tissue specific analysis revealed 48 % of AD gene candidates obtained from the literature curated PPIN were expressed in tissues where AD is observed compared to 19 % of gene candidates extracted using the high-throughput PPIN.
AB - Advances in high-throughput technologies along with the curation of small-scale experiments has aided in the construction of reference maps of the interactome. These maps are critical to our understanding of genotype-phenotype relationships and disease. However, our knowledge of disease associated genes and the map of the human interactome still remains incomplete. In this study we investigate whether protein–protein interaction networks (PPINs) constructed from either experimental or curated data have an impact upon disease network analysis. An integrative network-driven framework is implemented to integrate diverse heterogeneous data including: gene-expression, PPIN, ontology-based similarity, degree connectivity and betweenness centrality measures to uncover potential Alzhemier disease (AD) candidate genes. Two PPINs have been selected and constructed from (1) experimental high-throughput data and (2) literature-curated sources. Only a marginal overlap of protein pairs between the two PPINs (305 protein pairs) was observed. A total of 17 significant AD gene candidate genes were identified using the literature derived PPIN compared to 20 genes using the PPIN constructed from high-throughput data. Both approaches correctly identified the AD susceptible TRAF1, a critical regulator of cerebral ischaemia–reperfusion injury and neuronal death. Biological process enrichment analysis revealed genes candidates from the literature based PPIN are modulated in AD pathogenesis such as neuron differentiation and involved in KEGG pathways such as neurotrophin signaling pathways. Tissue specific analysis revealed 48 % of AD gene candidates obtained from the literature curated PPIN were expressed in tissues where AD is observed compared to 19 % of gene candidates extracted using the high-throughput PPIN.
KW - network analysis
KW - data integration
KW - protein interaction networks
KW - Alzheimer's Disease
UR - https://pure.ulster.ac.uk/en/publications/investigating-the-impact-human-proteinprotein-interaction-network-2
JO - International Journal of Machine Learning and Cybernetics
JF - International Journal of Machine Learning and Cybernetics
Browne F, Wang HHY, Zheng H. Investigating the impact human protein–protein interaction networks have on disease-gene analysis. International Journal of Machine Learning and Cybernetics. 2018 Mar;9(3):455-464. https://doi.org/10.1007/s13042-016-0503-5


text:
Q: React-redux: actions with variables so i've this action:
export const getMovieDettails = (id) => (dispatch) => {
    dispatch({type: GET_MOVIE_DETTAIL_LOADING})
    fetch(`api/movieId/${id}`)
        .then(response => response.json())
        .then(movie => dispatch({type: GET_MOVIE_DETTAIL_LOADED, payload: movie}))
        .catch(err => dispatch({type: GET_MOVIE_DETTAIL_FAIL, payload: "Error with API"}));
}

on App.js i do this:
const mapDispatchToProps = (dispatch) => {
  return {
    onGetShows: () => dispatch(getHomeShows()),
    onGetMovies: () => dispatch(getMoviesShows()),
    onGetSeries: () => dispatch(getSeriesShows()),
    onGetMovieDettail: (id) => dispatch(getMovieDettails(id))
  }
}

and then pass the function to
<Route path="/movie/:id"  render={(routeProps) => <MovieDettailsRouter key={routeProps.match.params.id} data={this.props.movieDettail} movieDettail={this.props.onGetMovieDettail} {...routeProps}/>}/>

so on MovieDettailRouter i do
componentDidMount() {
        console.log(this.props.match.params.id);
        this.props.movieDettail(this.props.match.params.id);
    }

but not work, how can pass the function with paramaters, for good experience i call all state and actions on App.js and then pass data on the component, for call without paramaters i don't have problems, everything it's fine, but here where i need to get the params for the actions 've problem, on v1 of App i don't use actions for this page, i use only for page without actions with params, but on this update i decide to use redux for every call on server and i need to understan how can pass an actions with params on components
Edit: Add the state on MovieDettailRoute

A: You don't seem to be passing the state to the MovieDetailsRouter component.
After the data is fetched, dispatched and the store changes all the components that are listening for that part of the store will update.
The component needs to have access to the state to get the data.
You can pass the data to the component by getting the part of the state that your action will update with mapStateToProps in the App component, and then pass it to the MovieDetailRouter

redpajama_set_name: RedPajamaStackExchange


Kavery Kaul's "Long Way from Home" is a sensitive, mature and thoroughly compelling documentary following the difficult paths of three teenage girls who enroll in private and prestigious New York prep schools. The girls are the proverbial fishes out of water in these tony environments: Cindy is the American-born daughter of Cambodian refugees, Sarah is an Egyptian Muslim and Sage is an African-American. None of them come from the economically privileged backgrounds that their white schoolmates enjoy.
All three are ready for the challenge, and not surprisingly there are setbacks along the way. Cindy's attempts at learning soccer and becoming part of the school's team are rough, but she pushes ahead with practice despite the obvious (to the viewer, at least) lack of athletic ability. Sarah is understandably touchy about how her classmates perceive her cultural heritage and religion, but she discovers a greater degree of indifference rather than hostility from her classmates. Sage acknowledges the catty nature of ninth grade girls, but for her part she intentionally keeps a lower and quieter profile to avoid feeding the perception of African-Americans being (in her words) loud and rowdy.
"Long Way from Home" is disturbing in its ability to puncture the happy myths of diversity and multiculturalism. The blending of different races, religions and economic levels is still not easy, even at this very late date, and the three girls in the spotlight discover that first-hand --- often with unhappy results (Sage notes the racial divide in the lunchroom, where white students and black students self-segregate at their own tables). The ability of all three to relate their experiences with eloquence and intelligence creates an extraordinary achievement that will provoke debate and dissection for those who dare to consider the serious lessons of this production. Non-fiction filmmaking doesn't get better than this.


Oliveda Anti Oxidant Face Cream is a 24 h cream and based on highly effective concentrate of fresh cell sap from the olive leaf instead of water. The olive tree cell elixir has a great anti-aging effect and also provides the skin with important nutrients. Recent research shows that it is because of this substance the olive trees are capable of living for up to 4000 years. The fresh active cell elixir has a firming anti-wrinkle effect on skin. Due to the high content of hydroxytyrosol it strengthens the skin's natural resistance, firms the skin and treats the first signs of skin ageing. The fresh Olive Leaf Cell Elixir and Rosemary Extract revitalize the functionality of the skin. The active Olive agents improve the lipid balance of the skin. Sage Extract, rich in antioxidants strengthen the skin's natural defense mechanisms.
Apply to the cleaned face twice a day in the morning and at night, avoiding the eye area.
Many celebrities swear by the Oliveda glow effect and are true fans of the brand. According to Style Magazine the most popular celebrities among Oliveda fans are: Madonna and Charlize Theron.
olea europea (olive) leaf cell extract, caprylic/capric triglyceride, olea europea (olive) fruit oil, elaeis guineensis (palm) oil, glyceryl stearate citrate, cetearyl ethylhexanoate, butyrospermum parkii (shea butter) fruit, glycerin, stearic acid (and) palmitic acid, potassium cetyl phosphate (and) hydrogenated palm glycerides, lanolin, tocopheryl acetate, citrus aurantium dulcis (orange) flower extract, caprae lac (goat milk) powder, saccharide isomerate, carbomer, maltodextrin, parfum (fragrance), sodium hydroxide, benzyl alcohol, benzoic acid, sorbic acid.


text:
The 2014–15 daytime network television schedule for four of the five major English-language commercial broadcast networks in the United States covers the weekday daytime hours from September 2014 to August 2015. The schedule is followed by a list per network of returning series, and any series canceled after the 2013–14 season.

Affiliates fill time periods not occupied by network programs with local or syndicated programming. PBS – which offers daytime programming through a children's program block, PBS Kids – is not included, as its member television stations have local flexibility over most of their schedules and broadcast times for network shows may vary. Also not included are stations affiliated with Fox (as the network does not air a daytime network schedule or network news), MyNetworkTV (as the programming service also does not offer daytime programs of any kind), and Ion Television (as its schedule is composed mainly of syndicated reruns).

Legend

 New series are highlighted in bold.

Schedule
 All times correspond to U.S. Eastern and Pacific Time scheduling (except for some live sports or events). Except where affiliates slot certain programs outside their network-dictated timeslots, subtract one hour for Central, Mountain, Alaska, and Hawaii-Aleutian times.
 Local schedules may differ, as affiliates have the option to pre-empt or delay network programs. Such scheduling may be limited to preemptions caused by local or national breaking news or weather coverage (which may force stations to tape delay certain programs in overnight timeslots or defer them to a co-operated station or digital subchannel in their regular timeslot) and any major sports events scheduled to air in a weekday timeslot (mainly during major holidays). Stations may air shows at other times at their preference.

Monday-Friday

Saturday

Sunday

By network

ABC

Returning series:
ABC World News Tonight
The Chew
General Hospital
Good Morning America
The View
This Week with George Stephanopoluos
 Litton's Weekend Adventure
Jack Hanna's Wild Countdown
Ocean Mysteries with Jeff Corwin
Sea Rescue
The Wildlife Docs
Born to Explore with Richard Wiese

New series:
Litton's Weekend Adventure
Outback Adventures with Tim Faulkner

Not returning from 2013-14
Litton's Weekend Adventure
Expedition Wild (Moved to The CW)

CBS

Returning series:
The Bold and the Beautiful
CBS Evening News
CBS News Sunday Morning
CBS This Morning
Face the Nation
Let's Make a Deal
The Price is Right
The Talk
The Young and the Restless
 CBS Dream Team
Lucky Dog
Dr. Chris Pet Vet
Recipe Rehab
All In with Laila Ali
Game Changers with Kevin Frazier

New series:
CBS Dream Team
The Henry Ford's Innovation Nation with Mo Rocca

Not returning from 2013-14
CBS Dream Team
Jamie's 15-Minute Meals

FOX

Returning series
Weekend Marketplace

New series:
Xploration Station
Xploration Awesome Planet
Xploration Outer Space
Xploration Earth 2050
Xploration Animal Science

The CW

Returning series:
The Bill Cunningham Show

New series:
One Magnificent Morning
Dog Whisperer with Cesar Milan: Family Edition
Calling Dr. Pol
The Brady Barr Experience
Expedition Wild (Moved from ABC)
Rock the Park
Reluctantly Healthy
Dog Town, USA

Not returning from 2013-14
Vortexx
The Adventures of Chuck and Friends  (continued on Discovery Family)
Rescue Heroes
Sonic X
Bolts and Blip
The Spectacular Spider-Man
Justice League Unlimited
Dragon Ball Z Kai
B-Daman Crossfire
Yu-Gi-Oh!
Yu-Gi-Oh! Zexal (continued on Nicktoons and Hulu)
Digimon Fusion (continued on Nicktoons)
Cubix: Robots for Everyone

NBC

Returning series:
Days of Our Lives
Meet the Press
NBC Nightly News
Today
NBC Kids
The Chica Show
Tree Fu Tom
LazyTown
Poppy Cat
Noodle and Doodle

New series:
NBC Kids
Astroblast!
Earth to Luna!
Ruff-Ruff, Tweet and Dave

Not returning from 2013-14
NBC Kids
Pajanimals (continues on Sprout)
Justin Time (continues on Sprout)
Make Way for Noddy (continues on Sprout)
Zou (continues on Sprout)

See also
2014–15 United States network television schedule (prime-time)
2014–15 United States network television schedule (late night)

References

Sources

United States weekday network television schedules
2014 in American television
2015 in American television

redpajama_set_name: RedPajamaWikipedia


Indiana Grandparent visitation is governed by the Indiana Grandparent Visitation Act, which sets forth the circumstances under which a grandparent may seek visitation rights with a grandchild. Under that law, a "maternal or paternal grandparent" includes (1) the adoptive parent of the child's parent; (2) the parent of the child's adoptive parent; and (3) the parent of the child's parent.
Generally, a child's grandparent may seek visitation if: (1) one (or both) of the child's parents is deceased; (2) the child's parents are divorced; or (3) the child was born out of wedlock. For paternal grandparents to seek visitation with a child born out of wedlock, it is necessary that their son's paternity over the child first be established.
Indiana courts, when considering a petition for the exercise of grandparents rights, first and foremost consider the best interest of the child. Once awarded, grandparent visitation rights survive the adoption of the child by a stepparent, or by someone biologically related to the child, such as another grandparent, a sibling, an aunt or uncle, or a niece or nephew.


text:
Sanga fails to turn up for PI – again; accused freed
4 Apr 2018 - 09:41PM
The virtual complainant, Jawansa "Sanga" Fraser. (Internet photo)
Three men accused of attempting to kill Jawana "Sanga" Fraser in Paul's Avenue last October were discharged on Tuesday after the virtual complainant failed to turn up to court as the preliminary inquiry continued.
Jomarno "Small Man" Tash walked out of the court a free man while Colin "Cocoa" David and Ricardo "Shrek" McFee remained in police custody in connection with other charges.
When the preliminary inquiry began on March 19, David's lawyer, Grant Connell, had argued unsuccessfully for an adjournment so that the matter could proceed when all witnesses were present.
The lawyer suggested that the virtual complainant, who lives a few hundred yards away from the court, would not turn up for the proceedings.
However Senior Prosecutor Adolphus Delplesche told the court that Fraser had not been properly summoned to attend court.
He asked Chief Magistrate Rechanne Browne-Matthias to hear the testimony of the three witnesses – all police officers – who has turned up for the proceedings.
However, after hearing the testimony of two of the officers, the court granted an adjournment until last Tuesday.
Fraser was shot and injured when the occupants of a car opened fire on him on Oct. 14, 2017.
Before the court was adjourned on Tuesday, David would be jailed for five years for possession of a firearm and 36 rounds of ammunition in Kingstown last May.
2 replies on "Sanga fails to turn up for PI – again; accused freed"
The judge says:
5th April 2018 at 1:10 PM
This is what is called a travesty of justice when the system is undermined by skulduggery.
This sounds like folklore. When people don't show up to court they are usually charged. What is this? Omerta tactics? or like the man said skulduggerous tactics. In a place full of Academics, one would expect better. Also sorry, but I won't mention my nickname. WTF!

redpajama_set_name: RedPajamaCommonCrawl


text:
Toronto 2014: 'Justice' review
Published on 7 September 2014 11 December 2017 by CineVue
Most of the contemporary cinema that European audiences get to consume from the Philippines come from visionary (and festival favoured) directors such as Lav Diaz or Raya Martin. The former's From What Is Before (2014) is not the only film from the country to feature in the programme of this year's Toronto International Film Festival, however. Also present is Joel Lamangan's urban crime drama Justice (Hustisya, 2014) but sadly, despite providing an interesting snapshot of contemporary Manilla, it's a patchy affair at best and completely unravels in its disastrous third act. As such, Justice also fails to make much of a case for a wider array of Filipino cinema to be given opportunities on international screens.
If you've ever wondered what a low-budget Filipino spin on Francis Ford Coppola's The Godfather (1972) with a middle-aged servant taking on the role of Michael Corleone might be like, then you need wonder no more. Biring (Nora Aunor) is the personal assistant to her childhood best friend, Vivian (Rosanna Roces), who is now the head of a successful people trafficking operation. When emotion gets the better of her after a betrayal, Vivian kills her former lover and chooses the loyal and unsuspecting Biring as her patsy. Somehow, Biring must navigate time behind bars, vested interests of local officials, and learn who set her up in order to exact revenge. The potential is there for Lamangan's to craft a really noteworthy thriller, casting an alternative light on the society so damned by his much-lauded compatriot, Lav Diaz.
The malignancy of governmental corruption stalks the story, whilst Biring is set up as staunch opposition to the apathy of the general populace, and the hypocrisy of the state religion. Instead she prays to the city, Manilla, a bustling, sprawling, deafening giant – Justice's greatest success is in forming a palpable sense of location. The problem is that all of these fascinating elements are just backdrop for the uneven and implausible plot. Once Biring is in lock-down, things take a turn for the strange with the introduction of the dapper Attorney (Rocco Nacino) who is charged with securing her freedom, and the cartoonish Butchie (Mailes Kanapi) the alpha female of the bizarre cell block. As Biring's quest for retribution continues, and begins to coincide with a unlikely rise through the Manilla underworld, events become increasingly ungrounded – undermining any karmic sense of balance being restored. To cap it all off, Justice's final scene attempts to cross the nuance of Sofia Coppola's Lost in Translation (2003) with the wicked conclusion to Michael Jackson's Thriller video – to completely dumbfounding effect. It's an aptly unconvincing ending to a film that's unfortunately difficult to recommend.
The Toronto International Film Festival takes place from 4-14 September 2014. For more coverage, follow this link.
Ben Nicholson, Toronto
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'Growth Stunt' is a self-produced and bass-heavy track that has influences from early Memphis rap and the current underground scene. Trash Gang has created an AMV for the track, adding to the aggression and grit of the beat and vocal performance.
Richard Alexander (born March 5th, 1994), known professionally as Haarper (often stylized as HAARPER), is an American Hip Hop artist from Vacaville, California. He has been producing beats since 2012 but has been involved with music the majority of his life. He learned to play guitar at a young age, eventually playing in metal bands throughout High School as well as serving as frontman on vocals for a few. A couple years after he received his first DAW (digital audio workstation), Ableton, he joined the Air Force to earn a steady income in order to further his interest in music. He is currently out of the military and pursuing music full-time.
Haarper's music is gritty, dark, combative and at times emotional and ethereal. Inspired by early Memphis rap artists as well as metal influences such as the Deftones, he blends the passion and intensity expressed from both genres into a cohesive and aggressive sonic display. Although he's only been rapping since 2016 and is a producer at the core, he manages to bring a variety of different vocal performances throughout his music, ranging from a deep and heavy low-pitched vocal delivery, to fast rapid-fire flows and catchy melodic rhythms.
Haarper has been releasing music seriously since late May of 2018, landing 2 of his tracks on Trash Gang's YouTube page, which currently stands around 1.3 million subscribers. He will be releasing more music videos and projects in the near future, as well as solidifying and perfecting his sound.


Printed aprons are often essential for your catering or retail business, as an addition to the company uniform or to be branded for a special event. This apron comes in a choice of 6 colours to complement your logo and has 2 pockets on the front. Prices shown are for your logo printed in 1-4 colours. Alternatively a price is shown for your logo embroidered in a maximum of 12 colours and 4,000 stitches.


text:
Tag: Lee Byung Hun
Review: Our Blues
Starring: Lee Byung Hun, Shin Min Ah, Cha Seung Won, Lee Jung Eun, Uhm Jung Hwa, Han Ji Min, Kim Woo Bin, Kim Hye Ja, Go Doo Shim
Number of Episodes: 20
Genre: Life, Drama, Melodrama, Romance
Where I Watched It: Netflix
Recommended By: Park Jimin
Who I Watched It For: Park Jimin
"Our Blues" takes on an omnibus-style drama, which tells the story of diverse characters that are somewhat interconnected, in one way or the other.
Lee Dong Suk, a guy born on the beautiful island of Jeju, sells goods from the mainland in his truck for a living. He meets Min Sun Ah, a girl with a mysterious past, who has come to Jeju to escape that life.
Park Jung Joon, a ship captain, falls in love with Lee Young Ok, a diver with a bright and bubbly personality.
Jung Eun Hee, a fish shop owner, reunites with her past lover Choi Han Soo. They cross paths in Jeju Island when he returns back, after realizing that city life is not for him.
I went into this drama because of Park Jimin. Jimin was singing one of the songs on the OST so to support my fellow Bulletproof Boyscout, I put this drama on my to watch list. I won't lie. This show started off really slow. The first couple of stories dragged for me and I wasn't sure that I'd continue because I had to hype myself up to watch the new episodes in the beginning but boy am I glad that I kept with it. With each passing week, I cried a little more and then when Jimin's song with Ha Sung Woon finally makes its debut? I cried EVEN MORE. The song matched the couple's story so well that I came to love the song even more as well.
There's a lot of characters to follow in this show but I loved each and every story, every character, and just the entire town. Lee Young Ok's character was hard to root for. She was so mysterious, so frustratingly hard to get to know that it turned me off but as her story starts to come to light more and more, I hated her less and less. While I didn't completely understand the reasons she did the things that she did to and for her sister, in the end, I was glad that she found a home and I was glad that she could stop running from her life.
Each character in this show had a story to tell and we saw them all. Big stories, little stories, stories told through other stories, the way that the writers meshed them all together was pretty great. I can't tell you which story was my favorite because it's a tie between the pregnancy story and the granddaughter coming to stay with the grandmother. I cried the most in those two stories but each story was pretty great in their own right. All of the actors did a fantastic job of bringing their characters to life and I loved that each character shined in their own way and added to the village that I came to know and love in the end.
There's a lot to love with this drama. Lots of great acting, a fantastic OST, and a lot of pretty eye candy to look at as well. The pacing is on the slower side but I thought it worked well with the kind of drama that this was. Everything comes at you but the overall feel of the drama is slow, steady, and oh so good. I really enjoyed this one and I think y'all will too.
Tags: 2022 Dramas, 4.5 Reviews, Cha Seung Won, Drama, Go Doo Shim, Han Ji Min, Kim Hye Ja, Kim Woo Bin, Korean Dramas, Lee Byung Hun, Lee Jung Eun, Life, Melodrama, Netflix, Park Jimin, Romance, Shin Min Ah, Uhm Jung Hwa


text:
Q: Hide toolbar on top of iPhone keyboard Is there any way in JavaScript or HTML to hide the toolbar from iPhone keyboard.
I only have one form input and I don't want the user to see the next, previous or done.
I am using PhoneGap.

A: Not possible. If you log into the Apple Dev Forums (under Web Technologies), an Apple Evangelist will tell you the same thing.

A: Well yes, it can be done. It has been discussed in several StackOverflow questions around. Here's one example of how it can be done
It might not be the prettiest solusion you'll ever see but it sure works and that's what matters.


text:
FGA Info
Corporate Affiliates
Guide Application
Associate Angler
Fishing Guide Directory
Sawfish News
11/01/2017 11:26 AM | Ron Presley (Administrator)
by Tonya Wiley, Havenworth Coastal Conservation
Following a listing as "Endangered" under the Endangered Species Act (ESA) for the US population of smalltooth sawfish (Pristis pectinata) in 2003, NOAA Fisheries (NMFS) designated critical habitat for the species in 2009. But what exactly does that mean and what does that do?
The primary reason for the decline of the smalltooth sawfish population in the United States was mortality following capture in various commercial and recreational fisheries. The secondary reason for the decline was habitat loss largely associated with coastal development and degradation. So the preservation of habitat is an important consideration for conserving the species.
Photo Credit: Juan Valadez, Two juvenile smalltooth sawfish swim in very shallow water near a river mouth in Everglades National Park.
For the purpose of the ESA, critical habitat is defined as the specific areas within the geographical area occupied by the species at the time of listing, that contain physical or biological features (1) essential to conservation, and (2) which may require special management considerations or protection. The definition also includes a provision for specific areas outside the geographical area occupied by the species at the time of listing if the agency determines that the area itself is essential for conservation.
A critical habitat designation protects certain features, particular attributes, of an area that are necessary to ensure the species does not go extinct and can recover to the point that protections of the ESA are no longer necessary. For smalltooth sawfish the features determined to be essential to the conservation of the species are red mangroves and shallow, euryhaline habitats characterized by water depths between the Mean High Water line and 3 feet measured at Mean Lower Low Water. Euryhaline means the area can have a wide range of salt content, or salinity, due to tidal fluctuations and freshwater input as occurs in estuaries, bays, and lower reaches of rivers. These features were determined to be essential because they provide nursery habitat for small, young sawfish providing both shelter from predators and an abundant source of prey.
Photo credit: Tonya Wiley, Havenworth Coastal Conservation: A researcher prepares to release a juvenile smalltooth sawfish captured in shallow water along a mangrove shoreline in Florida Bay. Research conducted under ESA permit #1352.
Two specific areas (units) located along the southwest coast of peninsular Florida were included in the critical habitat designation for smalltooth sawfish: the northern Charlotte Harbor Estuary Unit and the southern Ten Thousand Islands/Everglades Unit.
Photo credit: NMFS Office of Protected Resources: The two units of designated smalltooth sawfish critical habitat.
So now that we've described why sawfish critical habitat was designated and defined both the areas and features of critical habitat, let's look at how this affects coastal residents. How is the designation applied and what does it mean for coastal development or recreational activities? And how does the designation conserve the species?
The designation of critical habitat provides a significant regulatory protection—the requirement that Federal agencies ensure, in consultation with NOAA Fisheries under section 7of the ESA, that their actions are not likely to destroy or adversely modify critical habitat. The Federal Government, through its role in water management, flood control, regulation of resource extraction and other industries, Federal land management, and the funding, authorization, and implementation of a myriad other activities, may propose actions that are likely to affect critical habitat. The designation ensures that the Federal Government considers the effects of its actions on critical habitat and avoids or modifies those actions that are likely to destroy or adversely modify critical habitat.
Critical habitat can contribute to the conservation of endangered species in several ways. Designation under the ESA triggers a federal agency's obligation to use their authorities to further the purposes of the Act which includes proactive conservation efforts. Designation also helps focus the conservation efforts of other partners, such as State and local governments, nongovernmental organizations, and individuals.
Photo credit: Dana M. Bethea, NOAA Fisheries: A neonate (newborn) smalltooth sawfish was captured and released on a muddy bank along a mangrove shoreline in Everglades National Park. Research conducted under ESA permit #1352.
The critical habitat designation for smalltooth sawfish does not necessarily prevent a homeowner from building a dock or repairing a seawall, result in new slow motor zones, close an area to fishing, or limit access to areas. What the designation does do is add levels of review to ensure that any project which could alter those essential features is carefully considered before federal permits are authorized or funds are allocated. In the case of smalltooth sawfish, critical habitat was designated in 2009 and has not resulted in any closed areas or lost recreational opportunities. But it has led to the protection of shallow, mangrove-lined habitats which are important to the recovery of the smalltooth sawfish population.
For more information about the designation of critical habitat for smalltooth sawfish visit:
http://www.tandfonline.com/doi/full/10.1080/19425120.2012.676606


text:
North Carolina Stops Cities That Would Pass LGBT Protections
Rider Torrance
North Carolina's General Assembly rushed through a bill on Wednesday that will prevent cities and counties from creating their own anti-discrimination ordinances, in response to Charlotte passing an ordinance that would protect LGBT community members from being discriminated against, according to Buzzfeed.
The bill, HB2, passed in a special session and was approved 83-25 in the North Caroliana's House and 32-0 in the Senate, according to the Huffington Post. Reports claim all of North Carolina's Senate Democrats walked out on the vote.
The Charlotte ordinance, which was meant to take effect on April 1, would have let transgender citizens use bathrooms that align with their gender identity, ABC reports. It also would have provided certain housing protections for LGBT community members and would prevent businesses from discriminating against LGBT people. If HB2 is signed by North Carolina's governor, that ordinance will be nullified.
The opposition to Charlotte's ordinance claimed it would have let men prey on women and girls in bathrooms, which is an argument that has been outside of North Carolina. There is no evidence of a threat like this in places where nondiscrimination bills have been passed.
Outside of North Carolina's state government stopping cities and counties from passing their own discrimination laws, HB2 further lays out its own rules in regards to LGBT concerns.
North Carolina's bill mandates that all public restrooms and locker rooms are restricted to one sex, unless they are single occupancy. This rule specifies people will go to restrooms and locker rooms based on their biological sex, not their gender identity.
Another rule dictates all cities and counties in North Carolina must make sure school restrooms follow the same guidelines for separating people by their biological sex.
North Carolina's bill says any rules set by the state override rules laid out by city and county governments.
"It's common sense — biological men should not me be in women's showers, locker rooms and bathrooms," North Carolina GOP Rep. Dean Arp said before the vote.
The cost of the special session was $42,000-a-day, and it was rushed to precede the initiation of Charlotte's ordinance.
North Carolina lawmakers have been successful in convincing the public that these laws are about who gets to go in what bathroom, despite the fact these laws contain many other protections for members of the LGBT community. The same tactic was used in Houston, Texas, when opponents of these kinds of protections took down a law very similar to what was coming to Charlotte.
Democratic Attorney General Roy Cooper, who's running for governor, called today's vote "shameful." The current governor of North Carolina, Gov. Pat McCrory, has not indicated if he will be signing the bill or vetoing it.
The local North Carolina station WNCN has reported Gov. McCrory is expected to sign the bill.
"Rather than expand nondiscrimination laws to protect all North Carolinians, the General Assembly instead spent $42,000 to rush through an extreme bill that undoes all local nondiscrimination laws and specifically excludes gay and transgender people from legal protections," Sarah Preston, acting Executive Director of the American Civil Liberties Union (ACLU) of North Carolina, told WNCN.
[Photo by Sarah D. Davis/Getty Images]


text:
A new dawn for the Full Moon
By Ed Jefferson and Kim Inam
Country inn sold following deal brokered by Colliers International.
A country inn which has been at the heart of its rural community near Bath for centuries has been sold by global real estate advisor Colliers International.
The deal heralds the dawn of a new era for the Full Moon at Rudge, some 20 miles from Bath, a similar distance from the Longleat estate and a short drive from Frome.
The oldest part of the Grade II listed building is believed to date back as far as 1640 and started life as a coaching inn.
The property includes a large beer garden with far-reaching views of the surrounding countryside.
It currently has five en-suite letting bedrooms and a spacious function room which can seat around 85 people, and which features its own bar. The new owners, a family from Surrey, plan to increase the number of en-suite letting bedrooms to eight by renovating part of the old manager's apartment and converting a large ground floor office to a disabled access bedroom.
It's an intimate and welcoming pub with flagstone floors, a feature fireplace, plenty of cosy spaces and settles, and a skittle alley. The "new" Full Moon will retain and build on the authenticity of the past 400 years, while providing an experience fully aligned with modern comforts and needs.
The events room, with its terrace opening onto the large beer garden, will be significantly upgraded to host a day-time coffee bar and private events.
Ed Jefferson from Colliers International's hotels team said: "This is a charming country inn situated in an area well-known for its walking and local fishing rivers.
"The previous owner acquired it in 2017 and carried out a number of improvements before deciding to sell it, so it represents excellent value for money.
"There are attractive gardens to the front and rear, with plenty of room for a marquee, making this an ideal summer pub.
"It is only lightly-traded and offers plenty of potential for the new owners to complete the refurbishments, re-open the letting rooms and re-introduce a food offering, which means this could be an exciting new dawn for the Full Moon."
The Full Moon's new owners said: "The Full Moon's purpose is to create happy and memorable experiences for all our loyal locals and trusting guests, through providing honest, authentic, local, fairly priced and always lovely pub food, drink and a place to stay."
Related Experts
Ed Jefferson
Senior Surveyor
Call now +44 117 917 2011
I trained with a long established firm of specialist chartered surveyors and have been working in the leisure sector since 2010. I joined Colliers Hotels Agency team in 2017 to cover the South West region and am based in Bristol.
I have a strong agency based background and have specialised in the hotel sector for some time. My core focus is handling top quality privately owned hotels & Inns throughout the South West region.
Kim Inam
Call now +44 20 7344 6814
I have joined Colliers International after working for five years in local authority in-house communications roles, leading media and marketing in the environmental, licensing, regeneration and planning sectors.
Prior to joining local authorities I worked for eight years' experience in journalism in north London reporting on a wide range of subjects including politics, crime, health and housing. For three and a half years I managed the team of reporters to produce nine weekly newspapers, a monthly supplement and the newspapers' social media platforms.


Cliff Dumas is CCO, Executive Vice President and Director of Good Life Networks (TSX.V;GOOD) a programmatic digital technology company based in Vancouver, B.C.
Cliff's extensive career includes being the only Canadian broadcaster to achieve both a CMA and ACM award in the U.S. He is a CCMA Hall of Fame inductee and Board Member. He is also a multiple Mark Award winner for excellence in broadcast marketing.
Cliff is recognized as an expert in content creation, marketing and team management. He helped launch the CMT Network in Canada. A 30-year broadcast veteran, Cliff produced and wrote some of the biggest television events for CBC. Cliff has consulted and mentored hundreds of radio, television and entertainment professionals in the U.S. and Canada.
Cliff and his team at GLN designed and built the music site Claim2Fame, created to help emerging artists launch and promote their music careers.
"Cliff Dumas rocked our Millionaire Mastermind Participants world with his life changing tools and tips. They haven't stopped talking about the value of the knowledge that he shared since!"
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Working with cliff has been amazing! His experience and insight have been invaluable in shaping not only myself as an entertainer, but as a person as well. I would recommend the his program to anyone!
I was very impressed with his work and he's only gotten better since he worked with our morning teams in Kelowna. I value his experience as a performer and talent coach and you could hear an immediate impact on all shows after.
Captivating, targeted and well communicated. In a very short time, I learned some important and realistic do's and don'ts on how to capture and keep your audience engaged. The use of audience statistics, real life examples, and stories specific to our brand really helped the learning process. Thanks, Cliff!
"Cliff's ability to coach you how to deliver descriptive and compelling stories to your audience that keeps them wanting more is just part of his dedication. His knowledge of branding, and his ability to help you clearly understand your direction and build your brand, keeps you focused so you can reach your goals."
"I know first-hand how effective Cliff's success and experience is when it comes to being a coach and mentor. Understanding how to tell compelling stories in today's media is so important and Cliff is one of the best."
I've had the pleasure of working with Cliff Dumas for nearly 5 years as a voiceover artist in his capacity as the station voice of CHCH. Cliff has always delivered on time and has gone above and beyond the call of duty. He's been proactive and solution-oriented and has proven to be an integral part of the CHCH brand.
Turn your message into a movement!
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Claim2Fame is the first Social Music Platform (built by my team at GLN) designed for emerging artists to launch, grow and promote their careers. Claim2Fame is also a powerful community where fans can interact, connect with and support their favorite artists.


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Generación de imágenes Docker

Generación de imágenes Docker

Para generar las imágenes, ejecutar la aplicación y levantarla, previamente es necesario instalar Docker y docker-compose:

Instalar Docker (la versión debe ser igual o más reciente a 17.05.0-ce (2017-05-04))

Instalar docker-compose

Actualmente, el repositorio contiene 1 archivo Dockerfile y 2 archivos docker-compose

Dockerfile: Se usa para generar la imagen de la aplicación

dev.yml: Archivo de docker-compose para levantar los servicios necesarios y generar la imagen de la aplicación.

latest.yml: Archivo de docker-compose para levantar la aplicación a su última version. (ver instalación)

Para levantar toda la aplicacion, se puede correr:

$ docker-compose -f dev.yml up -d nginx

Si es la primera vez que se corre este comando, puede llegar a tardar bastante en descargar las imágenes.
Una vez terminado, dejar en el puerto localhost:80 la aplicacion ejecutándose, pero antes se debe correr un comando para inicializar el desarrollo:

$ docker exec -it andino /etc/ckan_init.d/init_dev.sh

También se pueden levantar los servicios por separado de la aplicación:

Los servicios:

$ docker-compose -f dev.yml up --build --abort-on-container-exit db sol redis postfix

La aplicación andino que tendrá el puerto 8080 y en el 8800 el datapusher.

$ docker-compose -f dev.yml up --abort-on-container-exit --build --no-deps portal

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$ docker-compose -f dev.yml up -d --no-deps nginx

Eso levantará la aplicación con el directorio actual ($PWD) disponible dentro del directorio /dev-app del container.

Para acceder a la aplicación, hacer modificaciones en runtime, basta con correr el comando:

$ docker-compose -f dev.yml exec andino /bin/bash

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Here are a few helpful self-management changes to stop angry arguments.
Remember, you can only change yourself. If you change yourself effectively, you will probably find that your spouse will change to adjust to the new you; but don't expect to change your spouse.
If one of you is extremely upset with the other, you might find it helpful to schedule an arguing time and set a time limit on your argument.
You will need to mutually agree beforehand that you will stop the discussion when the time runs out. This will help each of you to focus on the task at hand and set the stage for both of you that this is not going to be an endless barrage.
Of course, when you make these agreements, you have to stick to them or your word will lose credibility.
Another self-management skill that can help to stop angry arguments is listening to your partner.
You might think you already do this, and you might. However, the listening I mean is to give your spouse a turn to present his or her side of the story without interruption except for clarification.
Your job, then, is to demonstrate that you were truly listening by respectfully explaining back to your spouse what was said, even if you don't agree. Try to find areas of agreement.
Without being disrespectful to the gravity of your spouse's concerns, it is sometimes helpful to keep your part of the discussion lighthearted if you can. Even respectful humor can be helpful at times.
There is a fine line between what will be taken as mocking and what will be taken as humor, so be careful what you say.
Will you manage to eliminate angry arguing?
Some of you can read a suggestion and conceptualize the principal and put it into action. Others might have difficulty and you will need help in learning to manage your thinking and feeling. Learn more about getting marriage help.