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IATAMA June 1999
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iatama@rootsweb.com
Fwd: HEDGE & PALMER
--part1_1b47d7e7.24a3ad55_boundary Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: 7bit --part1_1b47d7e7.24a3ad55_boundary Content-Type: message/rfc822 Content-Disposition: inline Return-path: RoladexMOM(a)aol.com From: RoladexMOM(a)aol.com Full-name: RoladexMOM Message-ID: <1b47d7e7.24a154a8(a)aol.com> Date: Tue, 22 Jun 1999 17:05:44 EDT Subject: HEDGE & PALMER To: IATAMA-L-(a)rootsweb.com MIME-Version: 1.0 Content-Type: text/plain; charset="us-ascii" Content-Transfer-Encoding: 7bit X-Mailer: AOL 4.0 for Windows sub 11 I joined this list a month ago in hopes that someone could help me find out about the HEDGE and PALMER families that would have been in Toledo in 1872. James B. HEDGE was a printer and might have had a newspaper there or had been connected with one. What was the local newspaper at that time? He was married to Nellie PALMER and they had at least four children, one who was born in Toledo in 1872 by the name of John Garnet HEDGE. I would appreciate it very much if someone could help me as John Garnet HEDGE was my grandfather. Thank you Jean RoladexMOM(a)aol.com --part1_1b47d7e7.24a3ad55_boundary--
20 years, 6 months
RE: Wade Family Info
by Wade, Gary A.
Listees: My g-grandfather, William Wade, settled in Tama Co. in the early 1860's. He and his wife--Susan Ann Johnston Wade had seven children: Lindley, Mary Margaret, Harry, Maria, Anna, Arthur(my grandfather) and Winfield. Susan died in 1903 and William died in 1916. They came to Tama Co. from Fayette Co., Penn. Any listee with information about the Wades in Tama Co.(Toledo) area I would be very interested in hearing from. Thanks! gary a. wade Coordinator of Education/Research/QA Dept. of Rehab. Svcs.(0596) University of Texas Medical Branch 301 University Bovd. Galveston, Texas 77555-0596 > ---------- > From: IATAMA-D-request(a)rootsweb.com > Reply To: IATAMA-L(a)rootsweb.com > Sent: Friday, June 18, 1999 8:48 AM > To: IATAMA-D(a)rootsweb.com > Subject: IATAMA-D Digest V99 #17 > > <<Message: Microsoft Exchange Message>><<Message: SPENCER FAMILY>> > >
SPENCER FAMILY
by Jean Payton
Dear Listers: I seem to be striking out on all accounts today. I tried sending a message to Jenny who has volunteered to do look ups for both marriages and deaths in Tama County. I also tried sending a query to the Tama County Query List and that to is invalid. I am looking for the following family: Perry SPENCER and his wife Delia (Smith) and their three children Ellis L. , Emory and Emily who were twins were according to the 1870 Census were living in Columbia Twp. Tama County. In the 1880 Census Perry and his wife Delia and youngest son Emory are still living in Columbia Twp. but Ellis L. has moved on and I found him getting married in Keokuk, Lee Co., in 1886. He was my great grandfather. I would like to know who Emily married and I also would like to know who Emory married if possible. I lost the family after the 1880 Census. I would like to know if there is some kind person who could do a look up for the 1885 and 1895 Census to see if this SPENCER family is still in the area. I also know that Ellis L. and his wife Dora had their first son in Des Moines, Polk County March 13, 1887. I would also like to know if Perry and Delia died in Tama County and if so where they are buried. Thank you for any and all help that someone on this list can give me in this search. Jean Payton
Welcome to the IATAMA mailing list!! PLEASE SAVE THIS INFORMATION so you have it for future reference. PLEASE BE CONSIDERATE of your fellow list members. Some folks are beginners at computers and some to genealogy. The world is a better place when we are all patient with each other. Personal attacks, criticism, or flaming are never permitted. HOW DO YOU POST? Send an email to iatama@rootsweb.com WHAT SHOULD YOU POST? 1. Questions about your ancestors. Give as much detail as you can. 2. Interesting history that is relevant to the list. 3. Genealogy and family history conferences, even if they charge for admission. 4. Genealogy societies should feel free to post about their society and their websites. 5. Book reviews of genealogy books are reasonable to post. A list of books is not, but sharing a good genealogy book you've found is a good idea. 6. Links to personal blogs that are about genealogy. They can be your blog or another. Even if the blog has ads, that is not a problem. 7. New collections on various genealogy sites that are relevant. We don't want advertisements, but if you find an interesting collection on Ancestry, FamilySearch, Library of Congress, or some other site that has relevance to the list, let people know. WHAT SHOULD BE IN YOUR POST? 1. An informative but concise subject line. 2. When replying to a previous message, be sure to check that the intended recipient's address is showing in the Send To box of your email BEFORE clicking on SEND. 3. Proofread and be sure you want your post public. All posts go in the archives! WANT TO UNSUBSCRIBE? Send an email to iatama-leave@rootsweb.com and put unsubscribe in the subject and body and nothing else.


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Roses aren't just red. In fact, some are multi-colored. Check out this star with all of it's stripes! Whether you're looking for a total knock-out or not, we've got just about every shade and hue.
Oh, lantana! How you've grown! That's what you've been saying if you planted a perennial variety last year and watched as it's doubled in size from the year before. Lantana, both the annual and the perennial varieties, are gorgeous and easy-care plants to add mounding color to your landscape.
Aloha! from Hawaii's state flower! Hibiscus are in full bloom right now and spreading tropical vibes around the Old North State. You don't have to fly 12 hours to see something this pretty. Plant your own oasis! Click here for details.
The penta doesn't have stripes but it's flowers are shaped like stars! The five points on each flower head is where it got its name. These annuals love the sun but we know why you'll love them back. Penta are perfect for attracting pollinators like butterflies and hummingbirds.
Zinnias are the perfect way to add pops of color to your yard in the summer. Choose from just about every shade in the rainbow including green! These adorable plants are great for cut flower arrangements.
Gerbera daisies aren't just some of our faves. They're incredibly popular in the florist world. They're ranked the number five most used cut flower in the world just behind the rose, carnation, chrysanthemum and tulip. They're a gorgeous way to add pops of color to your landscape and always have the option of picking them for a beautiful arrangement to bring the outdoors in too. Find out more about Gerbera Daisies here.
Coral Bell
Many shade gardens don't get the color they deserve. Need to spice up your shady areas with a boost of color? Coral Bells are the perfect perennial addition for the fully shaded, partially shady and even the partially sunny spaces in your yard. Scroll through our slideshow to view six gorgeous Coral Bell varieties that might just make your shade garden pop!
Want a big bang for just a few bucks? Try planting Indian Blanket (Gaillardia pulchella). It's a flower that actually grows wild in North Carolina which means less work for you because it thrives off of our normal conditions and will keep coming back each year.
Echinacea (or coneflower) is a pretty little perennial with a unique center and because it's native to our area, it's easy to care for and perfect for attracting pollinators to the yard.
When all else fails, do a dollop of daisy. Daisies are prime for the picking to bring the outdoors in and are an old time favorite in all Southern gardens.
The list of brightly colored flowers that can grow in the shady areas of our yards in North Carolina isn't as long as we all wished. Impatiens are a go-to plant at the top of that list, however. So if your shade garden is looking drab, here's where to start.
No one wants to grow up but some plants do! So what's the best thing out there for your arbor, trellis or wall? We're really big fans of the mandevilla. Here's why...

redpajama_set_name: RedPajamaCommonCrawl


The probe tip traditionally used with near-field scanning optical microscopes comprises an optically pumped device that transmits light from a far-field source to the sample through either a hollow pyramid or an optical fiber, possibly leading to low optical transmission efficiency, undesirable heating of the tip or insufficient reproducibility with respect to probe fabrication.
Scientists at the University of Michigan in Ann Arbor, however, have overcome these limitations by incorporating an electrically pumped nanoscale light source on the tip of an atomic force microscopy (AFM) probe.
Researchers have described an electrically pumped nanoscale light source for use in near-field scanning optical microscopy, realized on the tip of an atomic force microscopy probe. As shown in the scanning electron micrograph above, they coated the tip with ultrathin films comprising an organic LED. As illustrated in inset (a), bipolar current injection leads to radiative charge recombination inside the organic layers on the tip. Insets (b) and (c) show optical micrographs of the probe in the "off" and "on" states, respectively.
Other investigators have reported electrically pumped light sources on AFM probes, typically using group III-V semiconductors, but the inorganic material that makes up the semiconductors is poorly compatible with the silicon-based microelectromechanical systems used as scanning probe substrates.
For this reason, the Michigan researchers, led by assistant professors Max Shtein and Kevin P. Pipe, began to explore the use of organic light-emitting diodes (OLEDs). After describing in 2006 the assembly of a circular OLED on a flat silicon cantilever, they found that positioning the light source within nanometers of the sample was difficult because of the planar geometry of the probe and because of the distance between the light-emitting region and the surface of the probe. Further complicating the matter, the probe fabrication included steps that necessitated additional tooling and sample transfers.
More recently, the researchers reported an OLED-based light source created directly on the tip of an AFM probe, offering simpler fabrication and a significantly smaller emissive region. They used a silicon nitride pyramidal AFM probe made by Veeco Probes of Camarillo, Calif., as a substrate and deposited the OLED on the probe's tip using vacuum thermal evaporation, vapor-phase deposition and ion-beam lithography.
They showed that, using the nonplanar substrate geometry, they could achieve localization of the charge injection, the charge recombination and the light emission. Also, by measuring and comparing the current-voltage characteristic in devices with and without the tip intact, and by acquiring electroluminescence and optical images with an optical microscope made by Mitutoyo America Corp. of Aurora, Ill., and a 12-bit CCD camera made by Opteon Corp. of Cambridge, Mass., they demonstrated that they could turn on the device at the tip only.
The researchers are in the process of applying this probe to the imaging of nanostructures and biological systems.
Nano Letters, ASAP Edition, Nov. 3, 2007.


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BEPS, MAPs and APAs, OECD
Does Australia's Updated MAP Guidance Meet MAP Peer Review Report Undertakings?
Michelle Markham (Bond University)/ December 17, 2018 /Leave a comment
On 30 August 2018 the OECD released the fourth round of BEPS Action 14 peer review reports on improving tax dispute resolution mechanisms. Included in this round was a report on Australia. The report concluded that Australia meets part of the elements of the Action 14, and in particular meets some of the requirements regarding the availability and access to mutual agreement procedure (MAP). Where Australia has deficiencies, it was reported that Australia is working on most of them.
Recently the Australian Taxation Office (ATO) announced on its website that it had reviewed and updated its MAP guidance. Taxation Ruling 2000/16 was accordingly withdrawn on 21 November 2018. In accordance with its undertakings in the Peer Review report, the updated ATO guidance now covers both transfer pricing and non-transfer pricing cases.
MAP and anti-abuse provisions
The MAP Peer Review report had noted that Australia's OECD MAP profile incorrectly specifies that access to MAP will not be granted when Australia's domestic anti-abuse provisions apply, which may have caused taxpayers not to submit MAP requests for cases where Australia's domestic anti-abuse legislation applies.
The updated ATO guidance provides that taxpayers are able to request MAP for tax that results from the application of Australia's general anti-avoidance rules in Part IVA of the Income Tax Assessment Act 1936. The new guidance on the ATO website now specifically includes the multinational anti-avoidance law and the diverted profits tax rules as part of the general anti-avoidance rules, an issue that was in need of clarification. However, it also states that Part IVA is not restricted by the application of Australia's tax treaties, and thus it prevails regardless of whether the resultant tax is contrary to the provisions of a treaty.
The guidance concludes that consequently the ATO cannot resolve a case under MAP to the extent that it involves the application of Part IVA. If this is the case, why would a taxpayer proceed with a MAP request in these circumstances? While the taxpayer is unable to obtain MAP relief from Australia where Part IVA is involved, it may seek unilateral relief from the other jurisdiction concerned in the MAP negotiations, and may enter into a MAP on this limited basis.
MAP and multilateral disputes
The updated ATO guidance now refers to MAP requests involving multiple jurisdictions. Multilateral MAP negotiations can take place where the taxpayer has presented separate and concurrent MAP requests under each bilateral treaty involved, and each jurisdiction has accepted the MAP request presented to them, and where every jurisdiction involved has a treaty providing for MAP with each of the other jurisdictions.
With the OECD's MAP Forum on Tax Administration focusing on ways to use multilateral case resolution procedures to the fullest extent, as many cases potentially impact the tax bases of more than two jurisdictions, this updated guidance will facilitate the resolution of multilateral MAP controversies.
MAP and taxpayer-initiated adjustments
The updated ATO guidance clarifies that a taxpayer may request a MAP where it has initiated an adjustment in good faith. The example is given of a taxpayer lodging a self-amendment request or a request under the domestic laws of a treaty partner country to amend a tax return to adjust the price of its related party transactions, or the profits attributable to a permanent establishment, to reflect arm's length conditions.
The ATO will consider a taxpayer's self-initiated adjustment as meeting the good faith requirement if it has fulfilled all its tax obligations related to the income or profits under the domestic laws of both tax jurisdictions properly and in a timely manner, clearly reflecting a good faith effort to ensure income and profits are correctly reported.
Multi-year resolution of issues through MAP
An oblique reference to multi-year requests being available through the MAP is contained in the list of information and documentation required in the updated ATO guidance for making a MAP request. This includes the provision of all relevant facts of the case and any documentation supporting those facts, including "income years or other periods."
MAP and audit settlements
The Peer Review report acknowledged that while it has provided access to MAP in all eligible cases, Australia's practice enables access to MAP to be limited in cases where taxpayers and the tax administration have entered into an audit settlement that contains a clause not to resort to MAP.
The updated ATO guidance does not specifically deal with the interaction between audit settlements and MAP. It is understood that the ATO is still considering this issue, and that the updated ATO guidance as a whole is regarded as being in development, with positions on MAP issues due to be clarified ahead of the Stage 2 peer review of measures taken to address any shortcomings identified in the Stage 1 Peer Review.
Australia undertook to provide updated MAP guidance in its Peer Review report, and it has fulfilled this task. Whereas the Peer Review report referred to previous problems in accessing Australia's MAP guidance, the information is now easily accessible on the ATO website.
While most of the information sought has been provided, the updated guidance would benefit from further clarification in places.
In relation to MAP availability in cases of the application of Australia's anti-abuse provision, it would be advisable for a comprehensive explanation to be provided, so that taxpayers are aware of their circumscribed options in relation to the application of Australia's anti-abuse provision.
The OECD has made it very clear in the Action 14 minimum standards that jurisdictions should not deny access to MAP in cases where there is an audit settlement between tax authorities and taxpayers. The author has previously referred to the potential for abuse in such situations, as auditors may offer taxpayers a choice between entering into an audit settlement under which penalties are not applied (a condition of which is that the taxpayer waive their rights to seek MAP assistance), or receiving a high assessment with no suspension of collection, but with access to MAP.
Taxpayers may be pressurised into accepting an audit settlement by threats of higher adjustments if a MAP resolution is sought, or simply seek to maintain a good working relationship with their home tax authorities by not proceeding with a MAP case. One problem with such audit settlements is that the treaty partner or even the home state competent authority may be unaware that a tax treaty has been improperly applied. The author recommends that the issue of whether MAP is available in cases of audit settlements in the Australian context be clarified as soon as possible.
To make sure you do not miss out on regular updates from the Kluwer International Tax Blog, please subscribe here.
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The Contents of Intertax, Volume 46, Issue 12, 2018
Ana Paula Dourado (General Editor of Intertax)/ December 19, 2018
Ana Paula Dourado (General Editor of Intertax)/ December 6, 2018


This example demonstrates how procedures save statistical analysis context and results into item stores and how you can use PROC PLM to make post hoc inference based on saved item stores. The data are taken from McCullagh and Nelder (1989) and concern the effects on taste of various cheese additives. Four cheese additives were tested, and 52 response ratings for each additive were obtained. The response was measured on a scale of nine categories that range from strong dislike (1) to excellent taste (9). The following program saves the data in the data set Cheese. The variable y contains the taste rating, the variable Additive contains cheese additive types, and the variable freq contains the frequencies with which each additive received each rating.
By default, PROC LOGISTIC uses the cumulative logit model for the ordered categorical response. The STORE statement saves the fitted model to a SAS item store named sasuser.cheese. The name is a two-level SAS name of the form libname.membername. If libname is not specified in the STORE statement, the fitted results are saved in work.membername and the item store is deleted after the current SAS session ends. With this example, the fitted model is saved to an item store named sasuser.cheese in the Sasuser library. It is not deleted after the current SAS session ends. You can use PROC PLM to restore the results later.
The following statements use PROC PLM to load the saved model context and results by specifying RESTORE= with the target item store sasuser.cheese. Then they use two SHOW statements to display separate information saved in the item store. The first SHOW statement with the PROGRAM option displays the program that was used to generate the item store sasuser.cheese. The second SHOW statement with the PARMS option displays parameter estimates and associated statistics of the fitted ordinal model.
Output 75.2.1 displays the program that generated the item store sasuser.cheese. Except for the title information, it matches the original program.
You can perform various statistical inference tasks from a saved item store, as long as the task is applicable under the model context. For example, you can perform group comparisons between different cheese additive types. See the next example for details.


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For individuals with greater short-term needs, this product allows for achieving 25,000-50,000 i.u. vitamin D3 per week without having to take multiple capsules. For the elderly, Vitamin D3 liquid is an easy to use form.
Take 1 drop daily with a meal. Not intended for infants. Store in a cool, dry place.
I tried for many years to raise my blood vitamin D until I talked to the people at Timothy's office. Taking the D3 serum along with other supplements, my levels went from the 40's to the 80's in short time.
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This is a great alternative to D3 supplement. No added fillers, such as those found in pharmaceutical or so called natural products containing wood filler. Glad I found it.


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Review: A One-Owner 2002 BMW M5
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This Is the End (2013)
Posted on November 25, 2013 by Felix Vasquez
You would think that "This is the End," a movie about a group of Hollywood actors that basically play themselves for no reason would be self serving and self indulgent. And you'd be correct. Even in its breaking of the fourth wall and satirizing of its stars (that probably only the stars and their friends really would find laugh out loud funny), "This is the End" isn't a bad movie. In fact for the first forty five minutes, it's really funny and works as a goofy apocalyptic horror comedy. The rest is just filler, endless montages, and flat improv (mostly from Rogen).
You really have to be aware of headlines involving the stars of this film to understand the jokes. And more importantly you really have to know the stars of the movie. Directors Evan Goldberg and Seth Rogen fill the screen with their friends and very in vogue comedians, many of whom I didn't quite recognize. The rest of the movie either plays up the reputations of the stars, or exaggerates them for comedic effect. To a varying degree of laughs. Michael Cera is known as a meek and humble guy, so it's funny to see he's a coke snorting, sex crazed jerk when partying. And James Franco is an artist, so the writers plays up Franco's bad art and his pretentions. Jonah Hill is known as mostly a nice guy, so he plays a very sensitive version of himself who is passive aggressive and obnoxious. And there's Craig Robinson for reasons I can't quite figure out.
I think the better fit for the cast would have been Kevin Hart, but Robinson was in "Pineapple Express," so he's in. Truly, Robinson is good for screaming like a woman for most of the movie, so his contribution is just that and only that. When Seth Rogen picks up friend and fellow actor Jay Baruchel for vacation, the two ready themselves for a fun week, which includes stopping by friend James Franco's house to party for the night. Of course a bunch of people show up, many of whom I assume are popular, and there's a pretty funny and brief cameo by Paul Rudd. When Jay and Seth witness a horrifying earthquake followed by mysterious blue rays of light carrying people in to the skies, the pair retreat to James' house, where an apocalypse has now taken place. With a group of men now stuck in Franco's house with limited supplies, they hope to wait out the end of the world and figure out why judgment day has left them stuck on Earth fending for themselves.
And looking for scenarios to fill the run time that eventually wear thin. There's a video diary meant to recall "127 Hours," there's a splitting of resources which include liberal use of a porn magazine, and eventually the writers just break the fourth wall altogether and stage a lame sequel of "Pineapple Express" which the guys use to pass the time. Really, "This is the End" is funny once Danny McBride enters the story. As Danny McBride. Again, I'm not too sure who he is, but once he wakes up in Franco's house to learn about the apocalypse, McBride really manages to steal the scenes away from literally every cast member. His one liners are hysterical, and his disgruntled grumbles really give the movie the shot in the arm it needs. That said, "This is the End" has a unique twist on the apocalypse horror comedy, with some excellent special effects, but writers Rogen and Goldberg run out of ideas before the second act and just half ass it until the end credits. It's a comedy definitely worth watching, but it's only a notch above mediocre, when all is said and done.
Now In Stores. Buy It Here!
This entry was posted in Movie Reviews and tagged Apocalypse, Comedy, Demons, Horror, Supernatural, Survival, T. Bookmark the permalink.
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The World's End (2013) →


The description of the laparoscopic management of benign-appearing ovarian tumors covers all aspects of the surgical procedure used for the management of benign-appearing ovarian tumors. Operating room set up, position of patient and equipment, instruments used are thoroughly described. The technical key steps of the surgical procedure are presented in a step by step way: intraperitoneal cystectomy, adnexectomy, results/complications. Consequently, this operating technique is well standardized for the management of this condition.


Yolanda Foster has been struggling with lyme disease over the past couple of years, but she has never struggled so much that she can't give great advice to her children. As shown on The Real Housewives of Beverly Hills, Foster has been raising her children and giving them advice through good and bad times. And both of Foster's daughters are now modeling, both of whom have followed in Yolanda's footsteps.
Yolanda Foster herself has been a model for a while, and she knows some tricks and tips from the industry. And now that her daughter, Gigi Hadid, is one of the most in-demand models at present, Yolanda wants to make sure that her daughter has all of the advice she needs.
According to a new Bravo report, Yolanda Foster may have taught her daughter well, because Gigi recently revealed that she won't change her body and her weight to suit the industry. In fact, she will eat a hamburger if she wants to, but she will also work out to stay healthy. But Foster's daughter wants to keep her figure the way it is.
"I've kinda had an easy time with the whole body image thing, just because from the second I walked into [modeling agency] IMG, I was like, 'This is what I wanna do with my career, but the one thing is that I'm not gonna lose a certain amount of weight. I'm not gonna be extremely skinny.' I just don't want to do that," Gigi has revealed.
It sounds like Yolanda Foster has taught her daughter well. Of course, Bella Hadid is also entering modeling. But Yolanda isn't concerned about the competitive aspect of modeling. Yolanda Foster knows that people who are looking for a blonde model will go for Gigi, while a tough look will be suited more for Bella.
"I was always kinda told that when I was becoming a model, don't live with a model because you get competitive," she revealed.
And as Yolanda Foster is supporting her girls, her daughters are in full support of their mother. Hadid recently revealed that her mother is doing well, despite the treatment. According to the Inquisitr, Yolanda has revealed that she has lost the ability to read, write, and even watch television.
"She had a small procedure a couple of days ago and can't be here, but I'm doing it all for her and I know that she'll be able to come to things soon," Gigi told Access of her Yolanda's treatment.
What do you think of Yolanda Foster's strong daughters?


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CD314 (NKG2D) antibodies, mouse
Clone: REA1175 | Dilution: 1:50
Clone REA1175 recognizes the mouse CD314 (NKG2D), a type II transmembrane homodimeric glycoprotein belonging to the C-type lectin-like receptor family. CD314 in mice is expressed on activated CD8
αβ T cells, NK cells, subsets of γδ T cells, IFN-producing killer dendritic cells, subsets of NKT cells, and activated macrophages. For signaling, CD314 associates with signaling adapters DAP10 and DAP12 and transduces signal via the PI3-kinase pathway and the Syk-Zap70 pathways, respectively. CD314 recognizes multiple ligands, which are either uregulated in response to cellular stresses such as heat shock, infection, and DNA damage or are constitutively expressed, such as on tumor cells. Known ligands of CD314 in mice include murine UL16-binding protein-like transcript (MULTI), H60 family proteins and the five retinoic acid-inducible proteins RAE-1α, β, γ, δ, ε. Interaction of CD314 with its ligands regulates cytotoxic response towards the cells bearing the cognate ligands.
Additional information: Clone REA1175 displays negligible binding to Fc receptors.
Klrk1, NKG2-D, NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member, Nkg2d
Antigen: CD314 (NKG2D)
Clone: REA1175
Alternative names of antigen: Klrk1, NKG2-D, NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member, Nkg2d
Distribution of antigen: T cells, NK cells, macrophages, dendritic cells, NKT cells
Available conjugates: APC, PE-Vio615, Biotin, PE
Splenocytes of C57BL/6 mice were stained with CD314 (NKG2D) antibodies or with the corresponding REA Control antibodies (left images) as well as with Anti-NK1.1 antibodies and analyzed by flow cytometry using the MACSQuant
Analyzer. Cell debris and dead cells were excluded from the analysis based on scatter signals and propidium iodide fluorescence or 4',6-diamidino-2-phenylindole (DAPI) fluorescence, as in the case of tandem conjugates.
Diefenbach, A. et al. (2000) Ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat. Immunol. 1(2): 119-126
McMahon, C. et al. (2002) The role of the NKG2D immunoreceptor in immune cell activation and natural killing. Immunity 17(1): 19-29
Yokoyama, W. M. et al. (2002) NKG2D recruits two distinct adapters to trigger NK cell activation and costimulation. Nat. Immunol. 3(12): 1150-1155
Takada, A. et al. (2008) Two novel NKG2D ligands of the mouse H60 family with differential expression patterns and binding affinities to NKG2D. J. Immunol. 180: 1678-1685
CD314 (NKG2D)-PE, mouse
30 µg in 200 µL (1)
cells in a final volume of 100 µL.
CD314 (NKG2D)-APC, mouse
CD314 (NKG2D)-PE-Vio615, mouse
150 µg in 1 mL (1)
CD314 (NKG2D)-Biotin, mouse


text:
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A new study led by Boston University School of Public Health (BUSPH) researchers and published in BMJ Open Sport & Exercise Medicine used machine learning to find and comb through exercise-related tweets from across the United States, unpacking regional and gender differences in exercise types and intensity levels.
Alzheimer's gene may impact cognitive health before adulthood
In the journal Neurobiology of Aging, UC Riverside psychology Chandra Reynolds asserts that those carrying the APOE4 gene score lower on IQ tests during childhood and adolescence. And the effect was stronger in girls than in boys. APOE4 carriers are up to three times more likely to develop late-onset Alzheimer's disease, which occurs in people 65 and older.
Study finds maternal race not a factor for children experiencing a 'language gap'
Researchers from the University of North Carolina at Chapel Hill's Frank Porter Graham Child Development Institute have discovered that race plays no role in the amount and quality of the words mothers use with their children, or with the language skills their children later develop.
Warming temperatures and changes in ocean circulation and salinity are driving the breakup of ice sheets in Antarctica, but a new study suggests that intense storms may help push the system over the edge.
Researchers at the Bellvitge Biomedical Research Institute (IDIBELL), published today in Molecular Cancer Research a study where they identify methylation patterns associated with different subtypes of breast cancer, and a subclassification of the group of "triple negatives", a breast cancer type typically associated with poor prognosis. In addition, researchers identified changes in DNA methylation associated with the response to docetaxel, a common therapy. The research was led by Dr. Eva González-Suárez, head of the IDIBELL Transformation and Metastasis research group.
Researchers have found that a gene known as AEBP1 may play a central role in the development, severity and potential treatment of liver disease, according to a study by Temple University, the Geisinger Obesity Institute and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope. One of the study's major findings is that AEBP1 regulates the expression of a network of at least nine genes related to fibrosis: AKR1B10, CCDC80, DPT, EFEMP1, ITGBL1, LAMC3, MOXD1, SPP1, and STMN2.
Sperm may offer the uterus a 'secret handshake'
Why does it take 200 million sperm to fertilize a single egg? Part of the reason is bombardment by the female immune system, which very few sperm survive. Researchers have discovered a molecular handshake between sperm and uterine cells that may help sperm evade this attack --or may help the immune system target the weakest sperm.
Heat transfer through a single molecule has been measured for the first time by an international team of researchers led by the University of Michigan.
A computational simulation suggests that insects may be capable of using the properties of light from the sky to determine their compass direction with an error of less than two degrees. Evripidis Gkanias of the University of Edinburgh, U.K., and colleagues present their findings in PLOS Computational Biology.
BIDMC researchers report that a daily moderate dose of resveratrol significantly preserved muscle function and mitigated muscle atrophy in an animal model mimicking Mars' partial gravity. Novel model innovated by BIDMC researchers will help scientists fill in the blanks about the little understood physiological consequences of partial gravity.
Synthetic chemicals, including pesticides, medications and household cleaners, often end up in our waterways. Even in small amounts these substances can affect wildlife, plants and humans, and a number of them have shown resistance to normal water treatment methods. Researchers at Carnegie Mellon University blazed the trail for a new field of sustainable chemistry by unveiling powerful, safe and inexpensive oxidation catalysts inspired by biological processes that break down even the most stubborn micropollutants.
Scientists discover group of genes connected to longer life in fruit flies
E(z) longer life: New insights on genes linked to longer life and higher fertility.
NASA's Aqua satellite finds Tropical Storm Danas over Ryuku Islands
NASA's Aqua satellite found Tropical Storm Danas moving over Japan's Ryuku island chain in the Northwestern Pacific Ocean.
Testosterone replacement therapy (TRT) can increase men's risk of stroke and heart attack
Aging men with low testosterone levels who take testosterone replacement therapy (TRT) are at a slightly greater risk of experiencing an ischemic stroke, transient ischemic attack (TIA), or myocardial infarction, especially during the first two years of use, reports a study appearing in The American Journal of Medicine, published by Elsevier. The findings confirm concerns voiced by many health agencies about the potential risks associated with the treatment.
Link found between gut bacteria, successful joint replacement
Having healthy gut flora -- the trillions of bacteria housed in our intestines -- could lower the risk of infection following knee and hip replacement surgeries, while an unhealthy intestinal flora may increase the risk of infection.
Researchers at Carnegie Mellon University have developed an automated, robotic training device that allows mice to learn at their leisure. The technology stands to further neuroscience research by allowing researchers to train animals under more natural conditions and identify mechanisms of circuit rewiring that occur during learning.
Lionfish ear-bones reveal a more mobile invasion
Researchers have little information about how grown lionfish might invade or move to new waters because tracking small marine organisms poses difficulties. One way to investigate their movements, though, is to study stable isotopes in their ear-bones.
CCNY physicists use mathematics to trace neuro transitions
Unique in its application of a mathematical model to understand how the brain transitions from consciousness to unconscious behavior, a study at The City College of New York's Benjamin Levich Institute for Physico-Chemical Hydrodynamics may have just advanced neuroscience appreciably. The findings, surprisingly by physicists, suggest that the subliminal state is the most robust part of the conscious network and appear on the cover of the journal 'Neuroscience.'
Researchers at Beth Israel Deaconess Medical Center embarked on a study to investigate whether early changes in energy-related metabolites in the blood -- measured shortly after chemotherapy -- could be used to identify patients who developed heart toxicity at a later time.
A sharper focus: New computational technique resolves compressed X-ray data
With high-energy X-rays, such as those that will be produced by the upgrade to Argonne's Advanced Photon Source comes a potential hitch -- the more penetrating the X-rays are, the higher a likelihood that researchers could run into problems with the image data. In a new study, researchers at Argonne have found a novel way to combat this image degradation.
U of Guelph researchers learn how low oxygen builds a bigger, stronger alligator heart
University of Guelph researchers are beginning to understand why some alligators develop stronger hearts after enduring low oxygen during early development in the egg.
Mothers living near more intense oil and gas development activity have a 40-70% higher chance of having children with congenital heart defects (CHDs) compared to those living in areas of less intense activity, according to a new study from researchers at the Colorado School of Public Health.
Under physiological conditions, only certain sequences within the genome, called flipons, are capable of dynamically forming either right- or left-handed DNA. When a flipon is left-handed, genes change the transcripts they produce, affecting how cells respond to their environment. The outcomes depend on both the shape and sequence of a gene's DNA, each feature encoding a different subset of genetic information: one dynamic, the other static. Both flipons and codons are subject to natural selection.
Strong family relationships may help with asthma outcomes for children
Positive family relationships might help youth to maintain good asthma management behaviors even in the face of difficult neighborhood conditions, according to a new Northwestern University study.
Neuroscientists from the Salk Institute and UC San Diego have discovered that at least six types of mammals--from mice to cats--distinguish odors in roughly the same way, using circuitry in the brain that's evolutionarily preserved across species.
Biomaterial-delivered chemotherapy leads to long-term survival in brain cancer
A combination of chemotherapy drugs during brain cancer surgery using a biodegradable paste, leads to long-term survival, researchers at the University of Nottingham have discovered.
UMN Medical School researchers explain muscle loss with menopause
New University of Minnesota Medical School research is the first to show that estrogen is essential to maintaining muscle stem cell health.
UCF team discovers, names new frog species
An international team of researchers have identified and described two new frog species and have named one of them after a University of Central Florida professor.
The widespread adoption of thermoelectric devices that can directly convert electricity into thermal energy for cooling and heating has been hindered, in part, by the lack of materials that are both inexpensive and highly efficient at room temperature. Now researchers from the University of Houston and the Massachusetts Institute of Technology have reported the discovery of a new material that works efficiently at room temperature while requiring almost no costly tellurium, a major component of the current state-of-the-art material.
What makes some people more receptive to the idea of being vaccinated against infectious disease?
Fear, trust, and the likelihood of exposure are three leading factors that influence whether people are willing to be vaccinated against a virulent disease, according to a new study in the journal Heliyon, published by Elsevier.
Women report skipping scientific conferences because of child care
Many women find themselves skipping scientific conferences because of family obligations, a new study finds. Women were less likely than men to attend scientific meetings, although both genders noted that conferences were important to career advancement.
Study: Even in competitive markets, shareholders bear burden of corruption
While the US traditionally ranks low on worldwide corruption indices, domestic political corruption still imposes substantial costs on US shareholders, according to new research co-written by Gies College of Business accounting professor Nerissa Brown.
When tornadoes touch down, we brace for news of property damage, injuries, and loss of life, but the high-speed wind storms wreak environmental havoc, too. They can cut through massive swaths of forest, destroying trees and wildlife habitat, and opening up opportunities for invasive species to gain ground.
Depressed by Facebook and the like
Great holiday, fantastic party, adorable children, incredible food: everyone shows their life in the best light on social networks. Those who take a look around on such sites can find that their self-esteem takes a hit as it seems as though everyone is better than them. Users who use social networks passively, i.e. do not post themselves, and tend to compare themselves with others are in danger of developing depressive symptoms.
The top five strangest poisons that can kill you (video)
There are some crazy poisons in this world of ours, and they're often found in things you'd least expect. In this week's episode of Reactions, we break down our top 5.
Needing to ride in a wheelchair can put the brakes on myriad opportunities -- some less obvious than one might think. New research from Michigan State University sheds light on the bias people have toward people with disabilities, known as 'ableism,' and how it shifts over time.
Porous metal-organic frameworks (MOFs) have many applications like carbon capture and water-cleaning. However, MOFs with large pores tend to collapse. Chemists and chemical engineers at EPFL have now solved the problem by adding small amounts of a polymer into the MOF pores, an act that impedes pore collapse.
Diversity on teams leads to positive outcomes, but not for all
Individuals on teams of diverse people working together can have better outcomes than those on teams with similar individuals, research as shown.
Diabetes medications masking surgical complication
A new class of diabetes medications is masking the potentially dangerous condition of ketoacidosis at the time of surgery. Testing for acid load in the blood of diabetes sufferers who are taking gliflozin medications is needed in order to avoid complications associated with ketoacidosis - a potentially lethal build-up of acid in the blood.
A better avenue for neurosurgery to improve outcomes
Changing the route of entry for minimally invasive neurosurgery provides better outcomes for a wide range of interventions, and is preferred by patients.
KAIST researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease (AD).
Scientists have confirmed that viruses can kill marine algae called diatoms and that diatom die-offs near the ocean surface may provide nutrients and organic matter for recycling by other algae, according to a Rutgers-led study.
Biochemistry: Versatile recycling in the cell
Ribosomes need regenerating. This process is important for the quality of the proteins produced and thus for the whole cell homeostasis as well as for developmental and biological processes. Biochemists from Goethe University Frankfurt together with biophysicists at LMU Munich have now watched one of the most important enzymes for ribosome recycling at work -- ABCE1 -- and shown that it is unexpectedly versatile in terms of structure.
Scientists discover how and when a subterranean ocean emerged
An international scientific team led by Russian geochemists have established that the huge reserves of water present in the Earth's mantle, which exceed the weight of the World Ocean, emerged over 3.3 billion years ago due to the immersion of seawater-rich oceanic crust into the depth of the Earth's interior. The results were published in Nature.
Researchers at the University of Sussex have identified how differences in the genetic sequence of the two main strains of the cancer-associated Epstein-Barr virus (EBV) can alter the way the virus behaves when it infects white blood cells.
Waking up sleeping bacteria to fight infections
Researchers in the group of Jan Michiels (VIB-KU Leuven Center for Microbiology) identified a mechanism of how sleepy bacteria wake up. This finding is important, as sleepy cells are often responsible for the stubbornness of chronic infections. Findings published in Molecular Cell reveal new perspectives on how to treat chronic infections, for example by forcing bacteria to wake up.
Scientists hope genetic research will lead to new breakthroughs in weed control
An article featured in the journal Weed Science sheds important new light on the genetics and potential control of Palmer amaranth and waterhemp - two troublesome Amaranthus species weeds that are resistant to multiple herbicides.
China, in collaboration with several countries, is now at the forefront of lunar exploration. In an article published on July 18 in Science, researchers laid out what the China Lunar Exploration Program (CLEP) has accomplished since their launch in 2007 and their plans into the next three decades.
A study by Marco Ce, a physicist based at the Helmholtz-Institut Mainz in Germany, and recently published in EPJ Plus describes a new technique for simulating particle ensembles that are 'large' (at least by the standards of particle physics). The technique improves the signal-to-noise ratio and thus the precision of the simulation; crucially, it can also be used to model ensembles of baryons: a category of elementary particles that includes the protons and neutrons that make up atomic nuclei.
New e-skin innovation by NUS researchers gives robots and prosthetics an exceptional sense of touch
NUS researchers have developed an ultra responsive and robust artificial nervous system for e-skins.
The art of sensing within the skin
The art of tattooing may have found a diagnostic twist. A team of scientists in Germany have developed permanent dermal sensors that can be applied as artistic tattoos. As detailed in the journal Angewandte Chemie, a colorimetric analytic formulation was injected into the skin instead of tattoo ink. The pigmented skin areas varied their color when blood pH or other health indicators changed.
Identification of autophagy gene regulation mechanism related to dementia and Lou Gehrig's disease
An international Research Team led by Dr. Jeong Yoon-ha at Korea Brain Research Institute has published the results of its research in 'Autophagy'. Expected to develop the treatment for neurodegenerative disease utilizing TDP-43 protein.
The risk factors for stroke and dementia are the same, and a growing body of evidence demonstrates that preventing stroke can also prevent some dementias. Now, a group of experts led by Western University Professor, Dr. Vladimir Hachinski and international collaborators Matthias Endres, Martin Dichgans and Zaven Khachaturian are calling on the global community to come together to take action on preventing dementia by preventing stroke. "The evidence for doing so is incontestable; the time to act is now," the authors write.
In a study published in EPJ D, physicists led by Wen-Shan Duan at Northwest Normal University, and Lei Yang at the Chinese Academy of Sciences, China, show that 'magnetic mirrors' plasma leaks can be minimised if specific conditions are met. The insights gathered by Duan and Yang's team could solve a decades-old problem of low plasma confinement times and high loss rates in magnetic mirrors.
Spread-changing orders and deletions affect stock prices
In a new study published in EPJ B, Stephan Grimm and Thomas Guhr from Duisburg-Essen University in Germany compare the influences that three price-changing events have on these spread changes. Their work sheds new light on the intricate inner workings of the stock market.
Lancet series, co-authored by NYU's Benzian, calls for 'radical reform' of oral healthcare
A special Lancet Series on Oral Health, published today in The Lancet, presents an 'urgent need for radical reform' of oral healthcare to prioritize prevention and integrate dentistry into primary care. The series is comprised of two papers, both co-authored by Habib Benzian, D.D.S., MScD.P.H., Ph.D., the associate director of global health and policy for NYU College of Dentistry's World Health Organization (WHO) Collaborating Center for Quality-improvement, Evidence-based Dentistry -- the only WHO Collaborating Center on oral health in the Americas.
Some pharmacists missing mark on therapeutic guidelines: QUT study
A study by researchers at Queensland University of Technology (QUT) in Brisbane, Australia, of more than 200 pharmacies has raised concerns that some are not adhering to therapeutic guidelines when distributing pharmaceuticals.
Survival of the zebrafish: Mate, or flee?
*Researchers have found that when making decisions that are important to the species' survival, zebrafish choose to mate rather than to flee from a threat.*The researchers identified specific brain regions associated with such decisions.*Understanding this basic biology is important when using zebrafish as a lab model for psychiatric diseases.
The most comprehensive synthesis of climate change impacts on the global availability of nutrients to date finds that, over the next 30 years, climate change and higher CO2 could significantly reduce the availability of critical nutrients, representing another challenge to global development and the fight to end undernutrition.
Emotion-detection applications built on outdated science, report warns
Software that purportedly reads emotions in faces is being deployed or tested for a variety of purposes, including surveillance, hiring, clinical diagnosis, and market research. But a new scientific report finds that facial movements are an inexact gauge of a person's feelings, behaviors or intentions.
Over-claiming knowledge predicts anti-establishment voting
People who think they know more than they actually do are more likely to vote against the establishment, shows new research out of the Netherlands.
Hypertension poorly managed in low- and middle-income countries
A study of 1 million people living in 44 low- and middle-income countries found that less than half of those affected with high blood pressure (hypertension) are aware of their condition.
Radical reform needed to address dental decay worldwide
Tooth decay, gum disease and oral cancers are a major health burden worldwide, but are largely ignored by the global health community, according to a series on oral health in The Lancet that publishes July 20, 2019. In a commentary accompanying the series, Cristin Kearns and Lisa Bero express growing concern that the dental profession will not make meaningful progress in combating the oral health epidemic until it addresses the sugar industry's influence on dental research.
Researchers at The University of Texas MD Anderson Cancer Center have discovered how an aggressive form of prostate cancer called double-negative prostate cancer (DNPC) metastasizes by evading the the immune system. The investigators also reported on the pre-clinical development of a new therapy, which, when given in combination with existing immunotherapies, appears to stop and even reverse metastasis in mouse models.
Canada's high school curricula not giving students full picture of climate change
Canada's high school students may not be getting enough information on the negative impacts of climate change, scientific consensus behind human-caused warming or climate solutions, according to new research from the University of British Columbia and Lund University.
Access to contraception not 'silver bullet' to stem population growth in Africa
The population of sub-Saharan Africa is set to double by 2050, yet a new study challenges a common misconception that this is caused solely by inadequate family planning.
Diabetes increases the risk of heart failure; more so in women than men
A global study of 12 million people has found diabetes increases the risk of heart failure and this increase is greater for women than men.
Low doses of radiation equivalent to three CT scans, which are considered safe, give cancer-capable cells a competitive advantage over normal cells. Researchers studied the effects of low doses of radiation in mice and found it increases the number of cells with mutations in p53, a well-known genetic change associated with cancer. However, giving the mice an antioxidant before radiation promoted the growth of healthy cells, which outcompeted and replaced the p53 mutant cells.
Species on the move
A total of 55 animal species in the UK have been displaced from their natural ranges or enabled to arrive for the first time on UK shores because of climate change over the last 10 years (2008-2018) -- as revealed in a new study published today by scientists at international conservation charity ZSL (Zoological Society of London).
The molten rock that feeds volcanoes can be stored in the Earth's crust for as long as a thousand years, a result which may help with volcanic hazard management and better forecasting of when eruptions might occur.
Diabetes increases the risk of heart failure more in women than men
Diabetes confers a greater excess risk of heart failure in women than men, according to new research in Diabetologia (the journal of the European Association for the Study of Diabetes). Type 1 diabetes is associated with a 47% excess risk of heart failure in women compared to men, whilst type 2 diabetes has a 9% excess risk of heart failure for women than men.
Oral health has been isolated from traditional healthcare and health policy for too long, despite the major global public health burden of oral diseases, according to a Lancet Series on Oral Health, published today in The Lancet. Failure of the global health community to prioritise the global burden of oral health has led to calls from Lancet Series authors for the radical reform of dental care, tightened regulation of the sugar industry, and greater transparency around conflict of interests in dental research.
Salt regulations linked to 9,900 cases of cardiovascular disease and 1,500 cancer cases
A relaxation of UK industry regulation of salt content in food has been linked with 9,900 additional cases of cardiovascular disease, and 1,500 cases of stomach cancer.
Nations with strong women's rights likely to have better population health and faster growth
Nations with strong women's rights are more likely to have better health and faster growth than those who don't promote and protect these values, finds research published in the online journal BMJ Open.
Music may offer alternative to preoperative drug routinely used to calm nerves
Music may offer an alternative to the use of a drug routinely used to calm the nerves before the use of regional anaesthesia (peripheral nerve block), suggest the results of a clinical trial, published online in the journal Regional Anesthesia & Pain Medicine.
Voluntary pact with food industry to curb salt content in England linked to thousands of extra heart
Since the introduction of the voluntary pact the UK government made with the food industry in 2011 to curb the salt content of food, the reduction in dietary salt intake in England has slowed significantly, reveals the first study of its kind, published online in the Journal of Epidemiology & Community Health.
Metal oxide-infused membranes could offer low-energy alternative for chemical separations
Researchers at the Georgia Institute of Technology are working on membranes that could separate chemicals without using energy-intensive distillation processes.
Hallucinations are spooky and, fortunately, fairly rare. But, a new study suggests, the real question isn't so much why some people occasionally experience them. It's why all of us aren't hallucinating all the time.
Coaching scientists to play well together
When scientists from different disciplines collaborate -- as is increasingly necessary to confront the complexity of challenging research problems -- interpersonal tussles often arise. One scientist may accuse another of stealing her ideas. Or, a researcher may feel he is not getting credit for his work or doesn't have access to important data. A free, online training tool developed by Northwestern, teamscience.net, has been proven to develop skills to work with other scientists outside their own discipline.
Many of the deadliest or most common cancers get the least amount of nonprofit research funding, reports a new Northwestern Medicine study. 'Embarrassing' or stigmatized cancers, like lung and liver, are underfunded. Colon, endometrial, liver and bile duct, cervical, ovarian, pancreatic and lung cancers were all poorly funded compared to how common they are and how many deaths they cause, the study found. In contrast, breast cancer, leukemia, lymphoma and pediatric cancers were all well-funded, respective to their impact on society.
'Trojan horse' anticancer drug disguises itself as fat
A stealthy new drug-delivery system disguises chemotherapeutics as fat in order to outsmart, penetrate and destroy tumors. Thinking the drugs are tasty fats, tumors invite the drug inside. Once there, the targeted drug activates, immediately suppressing tumor growth.
Scientists discover how mosquito brains integrate diverse sensory cues to find a host
A team, led by researchers at the University of Washington, has discovered how the female mosquito brain integrates visual and olfactory signals to identify, track and hone in on a potential host for her next blood meal. They discovered that, after the mosquito's olfactory system detects certain chemical cues, the mosquito uses her visual system to scan her surroundings for certain shapes and fly toward them, presumably associating those shapes with potential hosts.
Stimulating life-like perceptual experiences in brains of mice
Using a new and improved optogenetic technique, researchers report the ability to control -- and even create -- novel visual experiences in the brains of living mice, even in the absence of natural sensory input, according to a new study.
How sex affects gene expression in mammals
Researchers report the discovery of genome-wide variations in gene expression between mammalian females and males and offer new insights into the molecular origins and evolution of sexual dimorphism in mammal species, according to a new study.
Early mammal fossil reveals the evolutionary origins of having a loose tongue
Our highly mobile mammalian tongues, which allow us to swallow chewed food and suckle milk as babies, may have evolutionary origins in some of our most early mammalioform ancestors, according to a new study, which finds remarkably complex and modern mammal-like hyoid bones in a newly discovered 165-million-year-old mammaliaform species.
Special issue: 50th anniversary of the Apollo 11 landing
Fifty years ago, in July 1969, the Apollo 11 lunar module landed on the Moon and humans left their first mark on the surface of another world. In this special issue of Science, a Review, Policy Forum, Feature from Science's news department and an Editorial by Science Editor-In-Chief, Jeremy Berg, celebrate the semicentennial anniversary of the landing, its scientific impact and explore the potential future of lunar exploration.
Jumbo squid mystery solved
Stanford-led research identifies a perfect storm of warming waters and reduced food to blame in the collapse of the once lucrative jumbo squid fishery off Baja California.
Most magnets are rigid but have made great contributions to society and to modern industry, says Thomas Russell of UMass Amherst. But this award-winning innovator dreamed of more -- what if magnets could be soft and flowable as liquid to conform to a limited space? In Science this week, he and Xubo Liu from Beijing University of Chemical Technology, others at Berkeley National Lab and UC Berkeley, report on a simple way to transform paramagnetic ferrofluids -- plain metal particles in suspension -- into a magnetic state.
New species of flying squirrel from Southwest China added to the rarest and 'most wanted'
Described in 1981, the genus Biswamoyopterus is regarded as the most mysterious and rarest amongst all flying squirrels. It comprises two species, each known from a single specimen. Recent research by Chinese and Australian scientists described a third species found to inhabit low-altitude forests in Yunnan Province, China. By publishing their discovery in the open-access journal ZooKeys, the research team aims to promote further study and conservation of these squirrels.
Scientists at Berkeley Lab have made a new material that is both liquid and magnetic, opening the door to a new area of science in magnetic soft matter. The new material could lead to a revolutionary class of printable liquid devices for a variety of applications from artificial cells that deliver targeted cancer therapies to flexible liquid robots that can change their shape to adapt to their surroundings.
The 165-million-year-old fossil of Microdocodon gracilis, a tiny, shrew-like animal, shows the earliest example of modern hyoid bones in mammal evolution.
Brown neuroscientists discover neuron type that acts as brain's metronome
By measuring the fast electrical spikes of individual neurons in the touch region of the brain, Brown University neuroscientists have discovered a new type of cell that keeps time so regularly that it may serve as the brain's long-hypothesized clock or metronome.
Women now seen as equally as or more competent than men
Women have come a long way in the United States over the last 70 years, to the point where they are now seen as being as competent as men, if not more so, according to research published by the American Psychological Association.
Mars is about 9 months from Earth with today's tech, NASA reckons. As the new space race hurtles forward, Harvard researchers are asking: how do we make sure the winners can still stand when they reach the finish line? Published in Frontiers in Physiology, their study shows that resveratrol substantially preserves muscle mass and strength in rats exposed to the wasting effects of simulated Mars gravity.
Study examines differences over time in home dialysis initiation by race and ethnicity
Among US patients who started dialysis in 2005 to 2013, racial/ethnic differences in initiating home dialysis decreased over time, although in the most recent era, Blacks were still less likely to use home dialysis as the initial modality than other groups. Racial/ethnic differences in transfer from home dialysis to hemodialysis performed in dialysis facilities did not change over time. Minority patients continued to have lower mortality and kidney transplantation rates than White patients.
Higher kidney function at dialysis start linked with greater risk of death in children
In an analysis of information on children with kidney failure who began dialysis in the United States between 1995 and 2015, the risk of death was 1.36 times higher among children with higher kidney function at dialysis initiation. The risk of death was even greater for children with higher kidney function who initiated treatment with hemodialysis rather than peritoneal dialysis. In more recent years, children have been started on dialysis with higher kidney function.
A team at Fred Hutchinson Cancer Research Center has identified a gene that could make immunotherapy treatments, specifically checkpoint inhibitors, work for a wider variety of cancer patients. The study, published today in Developmental Cell, found that when the DUX4 gene is expressed in cancer cells, it can prevent the cancer from being recognized and destroyed by the immune system.
Researchers compare visceral leishmaniasis diagnostic tests
Accurate and timely diagnosis of the tropic disease visceral leishmaniasis (VL) is one of the pillars for reducing VL deaths. Currently available serological tests for diagnosing VL vary widely in their performance and may, as a whole, be inadequate for VL diagnosis, researchers report in PLOS Neglected Tropical Diseases.
Women no longer regarded as less competent than men but still seen as less ambitious
Good news for women -- they are no longer regarded as less competent than men on average, according to a nationally representative study of gender stereotypes in the United States. Less positive, however, is that women's gains in perceived competence have not propelled them to the top of hierarchies.
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Discussion in 'Sneaker Showcase' started by TheRealAlleygator, Feb 2, 2019.
Let's see what's yall copped!
info on the newcastle cap?
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Kyrie 3 for my 2 year old...7.99!
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text:
African swine fever holds back foodstuff segment and CPI
The African swine fever was named as one of the factors behind the slow rise of the CPI so far in 2019, despite the government's flexible monetary policy and an increase in gas and electricity costs.
Despite the swine fever, an increase in gas and electricity costs have pushed the CPI up
The General Statistics Office (GSO) reported that the average consumer price index (CPI ) in the first four months of this year increased 2.71 per cent on-year. This is the lowest average four-month CPI ascension as compared to the same period last year (2.8 per cent), and in 2017 (4.8 per cent).
"The increase in the prices of petrol and electricity was the key driver in the climb of the CPI in the first four months of 2019," said GSO's head Nguyen Bich Lam.
Specifically, in April the retail price of bio-fuel E5 RON 92 jumped VND1,115 to VND19,703 ($0.85) per litre, and that of RON95 increased to VND21,235 ($0.923), up VND1,484.
The prices of diesel and kerosene went up by VND297 and VND291 to VND17,384 (0.755) and VND16,262 ($0.7) per litre, respectively. Meanwhile, the price of mazut was capped at VND15,617 ($0.68) per kilogramme, up VND1,127.
In April alone, petrol retail prices rose by VND3,000 ($0.13) per litre after two continuous hikes.
Lam said that in March the average price of electricity went up 8.36 per cent under the Ministry of Industry and Trade's Decision No.648/QD-BCT, leading to an on-month 1.85 per cent hike in household-oriented electricity, a 1.42 per cent increase in the petrol price, and a 0.98 per cent rise in the materials for repairing houses.
However according to the GSO, the four-month CPI has been prevented from a bigger rise due to the appearance of African swine fever since March, affecting the consumption of pork, which occupies about 60 per cent of Vietnamese households' foodstuff consumption.
"In April, the price of pork dropped 3.07 per cent on-month due to consumer worries regarding African swine fever, and shifting to using other types of foodstuffs," Lam said.
Just like all other companies operating in the pork value chain in Vietnam, the US-backed Cargill Vietnam is now dealing with the fever, which is said will last long and has had a negative impact on all players' performance not only in Vietnam, but also in other nations hit by the disease.
Production and sales volume of feed and pork companies in Vietnam have decreased since March because the swine population in impacted areas is shrinking while farmers are reluctant or even not allowed to repopulate their farms amidst the disease, according to a Cargill Vietnam source.
The success of the four-month CPI was cited by the GSO to also derive from the State Bank of Vietnam's (SBV) flexible monetary policy, which since the start of the year has helped stabilise the value of the dong and the VND/USD exchange rate.
Deputy Prime Minister Vuong Dinh Hue has ordered the SBV to continue the policy in close combination with the fiscal policy in order to keep an inflation rate of between 3.3 and 3.9 per cent this year. The SBV has also been asked to control all monetary supplies and credit both in structure and quality, and to take all necessary solutions to continue stabilising the VND/USD exchange rate and lending rates at banks.
After recently working with the Vietnamese government, Alex Mourmouras, division chief in the International Monetary Fund's Asia and Pacific Department, said, "Vietnam's plans to modernise the monetary policy framework, including greater exchange rate flexibility to make the currency a better absorber of external shocks, are welcome. Gradual reserve accumulation should continue. To safeguard monetary and financial stability, the system of macroprudential regulations should be strengthened." VIR


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Enrique José Serrallés fue un escritor, poeta y novelista español. Nació en Cádiz, España, el 27 de julio de 1936, murió el 15 de septiembre de 1984 en Sevilla.

Biografía

Enrique José Serrallés fue hijo de Ivelisse Delgado y Jesús Alberto Serrallés. Vivió sus primeros años de vida en Francia, donde a la edad de tres años sus padres se trasladaron. A sus trece años de edad cambió demasiado al haber quedado huérfano de ambos padres en un aparatoso accidente automovilístico donde Enrique quedó gravemente herido.

Se trasladó a España donde vivió con su abuela paterna, Ramona Serrallés. A los quince años de edad comenzó a escribir poemas basándose en sus propias experiencias. Su primera novela publicada se titula Se apagó la luz, una novela basada en distintos asesinatos ocurridos entre 1933 y 1945, teniendo 19 años. La novela ganó el premio de literatura en 1950.

Se casó a la edad de 22 años con la venezolana Ángelica De Jesús. Tuvieron tres hijos: Pedro, Jesús y Cesár. Este último murió a la edad de tres años a causa de una neumonía.

Publicó su segunda novela El Horizonte en 1956. En 1963 publicó Adorno Floral dedicado a su hijo fallecido César. Publicó su cuarta novela en 1966 y estuvo basada en un sueño que tuvo en donde toda la tierra era color azul. Momentos de Paz fue su quinta novela y fue publicada en 1970, siendo reconocida en España, y ganó el premio de literatura. La Prueba, publicada en 1975, fue basada en la pérdida de sus padres. Vestido de Gala fue su última novela, la cual causó varias controversias ya que se dijo que fue un anticipo de su sorpresiva muerte.

Novelas

 Se apagó la luz
 El Horizonte
 Adorno floral
 Campo Azul
 Momentos de Paz
 La Prueba
 Vestido de Gala

Referencias

 Poetas.es

Poetas de España del siglo XX
Novelistas de España del siglo XX
Nacidos en Cádiz
Fallecidos en Sevilla

redpajama_set_name: RedPajamaWikipedia


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Wet Hot American Summer Returns to Netflix
Back in 2001 a little film called WET HOT AMERICAN SUMMER hit the big screen on only 12 screens and only made $295,000 US at the Box Office on a $1.8million dollar budget, so you would think "ahh who cares" well this movie has become somewhat of a cult hit and Netflix care's so much its reviving the movie into an 8 episode mini-series which has just started shooting.
Now for those who haven't seen the movie you might be quite blown away by the cast list…
Janeane Garofalo (Romy and Michele's High School Reunion)
David Hyde Pierce (TV's Frasier)
Marguerite Moreau (TV's Grey's Anatomy)
Michael Ian Black (TV's ED & Burning Love)
Zac Orth (TV's Revolution, Romeo & Juliet)
Paul Rudd (I Love You, Man)
Christopher Meloni (TV's Law & Order)
Molly Shannon (TV's Saturday Night Live)
Amy Poehler (TV's Parks and Recreation)
Joe Lo Truglio (Superbad, Pineapple Express)
Ken Marino (TV's Eastbound & Down)
Judah Friedlander (TV's 30 Rock)
Elizabeth Banks (The Hunger Games)
Kevin Sussman (TV's The Big Bang Theory)
Bradley Cooper (American Sniper, American Hustle)
Now WET HOT AMERICAN SUMMER was made before half of these actors about were even on a radar, Bradley Cooper had been only on a TV show I have never heard of and filmed an episode of Sex and the City same goes with Elizabeth Banks.
The synopsis from the movie
On August 18, 1981, Camp Firewood, a summer camp located near Waterville, Maine, is preparing for its last day of summer camp, which means counselors have one last chance to have a romantic encounter with another person at Camp Firewood. The summer ultimately culminates in a talent show.
Beth (Janeane Garofalo), the camp director, struggles to keep her counselors in order—and her campers alive—while falling in love with Henry (David Hyde Pierce), an astrophysics associate professor at the local college (actually Colby College). Henry has to devise a plan to save the camp from a piece of NASA's Skylab, which is falling to Earth.
Coop (Michael Showalter) has a crush on Katie (Marguerite Moreau), his fellow counselor, but has to pry her away from her rebellious, obnoxious, and obviously unfaithful boyfriend, Andy (Paul Rudd). Only Gene (Christopher Meloni), the shell-shocked Vietnam war veteran and camp chef, can help Coop win Katie—with some help from a talking can of vegetables (voiced by H. Jon Benjamin).
All the while, Gary (A.D. Miles), Gene's unfortunately chosen apprentice, and J.J. (Zak Orth) attempt to figure out why McKinley (Michael Ian Black) hasn't been with a woman; and Susie (Amy Poehler) and Ben (Bradley Cooper) attempt to produce and choreograph the greatest talent show Camp Firewood has ever seen.
Netflix has gone all out with this series getting pretty much ALL of the original cast back again plus even the original writers of the movie. I am intrigued to see how they end up shooting it because most of the actors above are rather busy these days shooting either TV shows or movies, maybe they will film it the same way they did with the last season of Arrest Development, where 90% of the time the other person in the scene wasn't actually in the room and it was just "creatively edited" to look like they were. BUT I am hopeful they will get them all back together fully and maybe we will even get to see some on the set pictures soon. Netflix did release this video 'teaser' for the new series.
Creator/Writer David Wain has said the TV series will be a prequel and will start at the beginning of Camp which should be interesting considering the actors are nearly 15 years older then what they were when the film came out.
I honestly can't wait to see this show, I've seen the movie around 20 times so I just hope it brings back the fun and weird of the original including the talking can of vegetables.
Darran
Darran loves watching movies, listening to movies and generally everything movies which is mainly the reason why he started accessreel.com and roped some friends in to help him.. Favorite Films: Star Wars, Lost in Translation, Grosse Point Blank, Shawshank Redemption and any Kevin Smith or Tarantino.


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Remarks by Ambassador Demetrios Marantis at Makerere University in Kampala, Uganda
Remarks By Ambassador Demetrios Marantis On U.S.-Malaysia Engagement And U.S. Trade Priorities In Asia
Remarks by Ambassador Kirk at the 2010 Agricultural Economic Outlook Forum
Remarks by Ambassador Marantis Before the Georgetown University Law Center
Remarks of Ambassador Kirk at the Detroit Economic Club
Remarks of Ambassador Ron Kirk at the Retail Industry Leaders Association Logistics Conference
Speeches/Transcripts
Remarks by Ambassador Demetrios Marantis
Deputy United States Trade Representative
*As Prepared for Delivery*
"Thank you very much for welcoming me to Makerere University. I am here today as Deputy United States Trade Representative representing President Obama's Administration on my first trip to Uganda. But I am also completing a trip to Makerere University that I began more than twenty years ago.
In 1989, as a junior in college, I spent the fall semester reading through the Rockefeller Foundation archives in Sleepy Hollow, New York. I was researching a paper on philanthropic foundations and the development of higher education in Africa - and that paper was to be focused in part on Makerere University. I flipped through dusty files and read hundreds of pages of reports. Every word and every page about Makerere told a story - a story of intellectual rigor, quality, and discipline. And every report I read painted a picture - a picture of hope and optimism not just for this university, but for Uganda and Africa as a whole.
It has been two decades since I first encountered Makerere University in those dusty archives. And in that time, many of those hopeful images have come alive. But my mind is still full of questions about the future. I am still asking questions about this University, about Africa, about your potential, and about the future of Africa and the United States together. That's why I'm here today.
Standing in this center of academic excellence, I cannot imagine being in a more hopeful place to ask these questions about the future of Africa and to find the answers together. Not only am I inspired by Makerere, I am inspired by Uganda and its people. Makerere University has educated each of you, and it is the alma mater of many African leaders, including former Tanzanian president Julius Nyerere, Kenyan President Mwai Kibaki, and Congolese President Joseph Kabila.
Uganda's history of meeting challenges and its trajectory of recent progress reminds us all that anything is possible. Who would have thought that an army of 27 could liberate a country from the bush? Who could have imagined that in 16 years a new, inexperienced government could reduce poverty by nearly 20 percent? Uganda has propelled its economy from no economic growth to more than 4 percent annual economic growth, and from hyperinflation to relatively low inflation. Uganda is taking on the scourge of HIV and AIDS, and has reduced an HIV/AIDS rate of 30 percent to less than 6 percent today. This effort deserves accolades, but it also needs to be maintained.
The relationship between the United States and Africa has also produced many successes on which we can now build. For almost a decade, the African Growth and Opportunity Act (AGOA) has proven that support for African exports can grow jobs and promote economic development on this continent.
Under AGOA, the United States has eliminated tariffs on almost all products from Uganda and from 37 other sub-Saharan African nations. From the very beginning, President Museveni understood what AGOA trade could mean for Ugandans. He has reminded us time and again that when we open markets, we open opportunities. Through AGOA, we are empowering Africans to trade up and out of poverty.
Over the last eight years, U.S.-sub-Saharan African trade - both exports and imports - has more than doubled. That means that, all across the continent, more Africans are building their lives and their communities by exporting more of the goods Americans want - jewelry, fruits, nuts, fruit juices, leather, plastic, cocoa, and much more.
At the same time, American companies and workers have found new opportunities to do business in Africa - providing inputs and expertise to aspiring African entrepreneurs, participating in joint venture partnerships, and increasing American exports and investment.
We have also succeeded in building Africa's capacity to trade with the United States. Trade capacity building assistance is a critical element in the effort to help African countries turn trade opportunities like AGOA into exports. And the United States has worked hard to ensure that African nations have the resources they need to seize the benefits of trade. In 2008, the United States provided over one billion dollars in trade capacity building assistance to sub-Saharan Africa, more than double the amount of funding in 2001. And today, there are four regional American trade competitiveness hubs that are funded by USAID in sub-Saharan Africa.
The nearest of these, in Nairobi, Kenya, serves all of East Africa, including Uganda. At that hub, Ugandans can receive AGOA-related training and technical assistance. All told, the trade support provided by the Nairobi hub is estimated this year to have produced well over $14 million in export sales for East African businesses.
The Nairobi Hub has also worked to streamline trade and reduce costs by developing a one-stop border post at the joint railway station at Malaba on the Kenya-Ugandan border. Customs officials working side-by-side are now able to clear goods in a fraction of the time previously required - saving African companies tens of millions of dollars in transport costs every year.
Despite all of these successes, more work lies ahead for Ugandans, Africans, and Americans as well. Especially in trade and economic policy. Africa benefits too little from global trade. Because Africa lacks capacity, global capital is still too timid about most countries in Africa, fearing instability and uncertainty. While many African countries made significant progress in liberalizing trade and instituting market-oriented reforms during the 1980s and 1990s, Africa's overall trade policies remain the world's most protectionist. Average African tariffs are nearly 20 percent. This is compared to just over 10 percent for the rest of the world, and 5 percent for industrialized countries. Many African countries lack manufacturing capacity and face challenges such as high energy and transportation costs. This makes products less competitive in global markets. This region will have to continue down the path of reforms and open trade to enhance its ability to attract foreign capital. Success in this regard will address supply-side constraints, further integrate the region into the global economy, and pull millions out of poverty.
The changing global economic dynamic also demands that we do more. The world is emerging from an economic crisis. Last year, even the strongest trade relationships suffered. During the first 11 months of 2009, total imports under AGOA declined by over 50 percent. Other global trends are changing how Africa trades - such as the end of global textile and apparel quotas - and China and other Asian countries becoming more competitive than ever. Historic trade relationships now face a growing web of bilateral free trade and economic partnership agreements.
Ugandans, Africans, and Americans need to face these challenges. We must work together to find and implement the right policies that work for Uganda, Africa, and the United States. I am committed to doing just that. I will be honest with you that when I first turned in my paper on Makerere University, my professor rejected it. He did not like some of my ideas and he did not agree with some of my conclusions. So I worked with my professor to rewrite and rework my paper until I got it right. Today, just like 20 years ago, I am committed to working with you to get things right. Together we can find the right economic policies, the right trade policies, and the right solutions for Uganda's and America's mutual prosperity.
Together, we must look towards the future to realize a common vision for Africa. And in my many conversations with my African colleagues, they have affirmed that we share a common vision. We share a vision where African countries do their part by making trade a priority in their development programs. We see African governments, businesses, and civil society working together to maximize the potential of AGOA by promoting African competitiveness and regional integration.
You and I both see that Africans can become more globally competitive by improving their countries' business environments and nurturing entrepreneurial initiative to expand and diversify exports. Here in Uganda, that could mean efforts to add value to and increase exports of your plentiful raw materials - things like cotton, tea, tobacco, sugar, wood products, cereals, milk, and leather.
We also see Africans stimulating economic growth by improving economies of scale and reducing cross-border costs through regional economic groups. I am pleased that the leaders of more than two dozen African countries have committed to work toward a regional free trade area stretching from the Mediterranean to the Cape of Good Hope. A commitment that promises to boost regional trade, improve African competitiveness, and create opportunity for African workers and families.
But vision is not enough. Which is why the United States and the Obama Administration are working with African regional organizations and their member countries to support regional initiatives. Yesterday, I participated in the first-ever council meeting under the U.S.-East African Community (EAC) Trade and Investment Framework Agreement - or TIFA, as we call it. The purpose of our TIFA is to deepen U.S. economic engagement and cooperation with Uganda and the other four members of the EAC (Kenya, Tanzania, Rwanda, and Burundi). Under the TIFA, we now have regular, high-level talks on the full spectrum of U.S.-EAC trade and investment topics, including AGOA, the World Trade Organization's Doha Round, trade facilitation issues, and trade capacity building assistance.
This work with the EAC further increased my confidence in the potential of East Africa to realize even greater tangible benefits from trade. Together the United States and the EAC can work to lay the foundation, establish commercial and other linkages, and chart the future course for stronger trade and investment opportunities for Uganda and neighboring countries.
I realize that this is a time of great promise, challenge and choice for the region. I want to work with Africa as it moves from the margins to the mainstream of the global economy. Your progress is also in our national interest. And we are committed to working with you to write a new chapter in U.S. trade ties with this region.
When I finally turned in that paper on Makerere University at the end of my junior year in college, my professor read it and gave me a grade - a B+. While a B+ was good enough for me in college, the common challenges Ugandans, Africans, and Americans face today demand we do better. We need to get an A. And if we work together - patiently, cooperatively, and respectfully - I am certain that we will earn the highest marks."


innocent's sustainability manager, Jess Samson, has been chosen by Ethical Corporation as one of the "individuals who have done the most to advance the cause of responsible business over the year". I'm sure you'll agree that this is a huge achievement, especially as her fellow nominees include such characters as Bill Gates and Barack Obama!
Congratulations Jess! Keep up the excellent work!