Today, Aldous Harding has aired a brand new song, entitled 'Elation'. Taken from the recording sessions for her recent album Party, Harding assumes the role of chanteuse, as the slow-burn of 'Elation' builds from a quiet lament to a dramatic zenith.
Earlier this summer, Harding performed the track exclusively for KEXP. Check out the startling performance bellow.
Aldous Harding's second album 'Party' was recorded with the award-winning John Parish (PJ Harvey, Sparklehorse) in Bristol, taking Harding away from her New Zealand base for an intensive two-week immersion in the studio. As well as a raft of musical contributions from Parish, Perfume Genius's Mike Hadreas lends vocals to recent single 'Imagining My Man' and 'Party' closer 'Swell Does The Skull'. Full of sinister torch songs, quiet opines and eerie odes 'Party' has dazzled critics, leading to a startling performance of 'Horizon' on Later... with Jools Holland (which can be viewed here).


Patients with rheumatoid arthritis are likely to experience the same level of cardiovascular benefits from statins as other individuals without incurring additional risks, according to new research.
The findings of a large clinical trial carried out by researchers at institutions including the University of Dundee appear in Arthritis & Rheumatology.
Patients with rheumatoid arthritis have an approximately 50% higher risk of experiencing cardiovascular events such as heart attack and stroke. By lowering cholesterol, statins are known to help prevent cardiovascular events in certain high-risk individuals but it was unclear whether they are safe and effective for patients with inflammatory conditions such as rheumatoid arthritis.
To investigate the potential risks and benefits of statins in moderate risk patients with rheumatoid arthritis, researchers compared the statin atorvastatin with a placebo. At the end of the trial, patients taking atorvastatin had significantly lower cholesterol as well as significantly lower levels of C-reactive protein, a marker of inflammation, compared with patients taking the placebo. Adverse events in the atorvastatin and placebo groups were similar.
Dundee's Professor Jill Belch, co-senior author of the paper, said, "It was important to establish that statins were safe for rheumatoid arthritis patients to take and that they experience the same kind of benefits from taking them as the general population.
The trial included 3,002 patients with rheumatoid arthritis who were over aged 50 years or had rheumatoid arthritis for more than 10 years, without clinical atherosclerosis, diabetes, or myopathy. Patients were randomised to receive atorvastatin 40mg daily or placebo.
During a median follow-up of 2.5 years, 1.6% of patients who received atorvastatin and 2.4% of patients receiving placebo experienced cardiovascular death, heart attack, stroke, transient ischemic attack, or any arterial revascularisation. After adjustments, there was a 40% lower risk of cardiovascular events for patients taking atorvastatin, although the difference was not statistically significant. This was because the overall rate of events was low.
Professor Belch carried out the project in conjunction with Professor George Kitas, of Dudley Group NHS Foundation Trust, and Professor Deborah Symmons, of the University of Manchester.
An accompanying editorial in Arthritis & Rheumatology notes that the study provides information that will prove useful for researchers and clinicians who focus on rheumatoid arthritis, and the results may be helpful when considering cardiovascular risk across other rheumatic diseases.


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At the media launch of the Otter African Trail Run 2012
Wednesday night saw the media launch of the 2012 Otter Trail Run held at the 2 Oceans Aquarium in Cape Town. With the predator's exhibit as a backdrop, I couldn't help myself thinking how fitting this slightly intimidating, yet thoroughly fascinating atmosphere was for Mark Collins to showcase the brainchild of his events company, Magnetic South.
The Otter Trail itself is unquestionably the most well-known hiking trail along the Garden Route of South Africa (from Storms River Mouth to Nature's Valley) and is situated within the Tsitsikamma National Park, in the Eastern Cape. With bookings for this 5-day trail extending throughout the year to well over a year in advance, it is undoubtedly one of the most magnificent treasures along our eastern coastline. What a privilege then, to be able to run this same 42Km trail, that would otherwise be closed to running in the other 364 days of the year, in a single day through an event that the organisershave aptly dubbed "The Grail of Trail"
The route itself is an imposing beast that belies its standard marathon distance. For those not akin to the nuances of trail running I would foresee more than a few runners being lulled into a false expectation here and many times the comment was made that this is more akin to an ultra-marathon in toughness. With no fewer than 11 "significant" climbs and a total elevation gain of 2600 metres over the course, with 4 river crossings thrown in the mix, this truly is a challenge for any trail runner.
Would like to read the entire article – click here
Compiled by Roan Mackintosh from Roan Mackintosch on behalf of Go Trail magazine
The Grail of Trail is Live on SuperSport
McCann Shatters the Course Record to Claim R150 000 at the Otter African Trail Run
The Otter African Trail Run Mourns the Passing of a Challenge Participant
Fuelling for Success with KAUAI at the Otter African Trail Run
EasyEquities makes investing easy by doubling the prize money at this year's Race.
Sealand – The Official Otter African Trail Gear Partner
The Otter's Creatures
Joining the likes of UTMB, Otter Race is now ITRA registered

redpajama_set_name: RedPajamaCommonCrawl


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Home Carolina Downhome Blues Festival
Carolina Downhome Blues Festival
Oct 3, 2019 to Oct 5, 2019
Fine Arts Center of Kershaw County 810 Lytlleton St., Camden, South Carolina 29020
Three days, 20 acts, 14 venues, 36 shows! For 23 years, the Carolina Downhome Blues Festival has been known for its legendary blues artists from around the globe, performing in multiple venues in an "up-close-and-personal" atmosphere, as well as its "blues crawl" format. Deemed by Southern Living as a "destination weekend," the Carolina Downhome Blues Festival attracts both blues aficionados as well as fans new to the blues music genre. All-access armbands are $15 for Thursday, $25 for Friday and Saturday and $60 for a Weekend Pass and will be available for purchase along with commemorative T-shirts and limited edition 23rd annual Carolina Downhome Blues posters.
Host hotels are the Comfort Inn & Suites, the Holiday Inn Express and the Hampton Inn. Special rates are available for Blues patrons this year — be sure to mention the festival when you make your reservation.
Thursday, Oct. 3:
Food For the Soul, 11:30 a.m. to 1 p.m. — Robert Lighthouse
Performing Arts Wing, 5:30 to 7 p.m. — Gerard Delafose & the Zydeco Gators
Sam Kendall's, 7 to 9 p.m. — Jeff Liberty
Salud, 7 to 8 p.m. — Suzie Vinnick
Steeplechase, 7 to 10 p.m. — Robert Lighthouse
Salud, 8 to 10 p.m. — Randy McAllister
Gadgets, 8 to 11 p.m. — Downtown Abby & the Echoes
Baron's, 9 p.m. to midnight — Shawn Holt & the Teardrops
Friday, Oct. 4:
Lugoff-Elgin H.S., 9:30 to 10:30 a.m. — Shrimp City Slim with John Clam Chop Etheridge, Suzie Vinnick and Randy McAllister
Sam Kendall's, 12 to 2 p.m. — Robert Lighthouse
Salud, 12 to 2 p.m. — Shrimp City Slim
Sam Kendall's, 7 to 10 p.m. — Suzie Vinnick
Salud, 7 to 10 p.m. — Rockin' Johnny Burgin
Steeplechase, 7 to 10 p.m. — The Blues Doctors
La Fiesta, 7 to 10 p.m. — Downtown Abby & the Echoes
Gadgets, 8 to 11 p.m. — John Lee Murphy
Performing Arts Wing, 8 to 10 p.m. — Randy McAllister
Baron's, 9 p.m. to 1 a.m. — Chris O'Leary Band
Saturday, Oct. 5:
Farmers' Market, 9 to 10 a.m. — Shrimp City Slim with BBQ Bob Donnan and John Clam Chop Etheridge
Sam Kendall's, 12 to 2 p.m. — Shrimp City Slim
Salud, 12 to 2 p.m. — Blues Deluxe Duo
Steeplechase, 12 to 2 p.m. — Jeff Liberty
Davis & Sons Guitar Shop, 1 to 4 p.m. — Rusty Davis & friends
Bassett Gallery, 1 to 2 p.m. — Rockin' Johnny Burgin
Bassett Gallery, 2 to 3 p.m. — Chris O'Leary
Books on Broad, 2 to 3:15 p.m. — The Blues Doctors
Wood Auditorium, 3 to 4 p.m. — Drink Small
Performing Arts Wing, 4 to 6 p.m. — The Blues Doctors
Performing Arts Wing, 7 to 9 p.m. — Chris O'Leary Band
Sam Kendall's, 7 to 10 p.m. — Professor Bottleneck
Steeplechase, 7 to 10 p.m. — Suzie Vinnick
La Fiesta, 7 to 10 p.m. — Randy McAllister
Gadgets, 8 to 11 p.m. — Kyle Yardley Blues Band
Baron's, 9 p.m. to midnight — The Good, The Bad, and the Blues
Sunday, Oct. 6:
Grace Episcopal Church, 10:30 a.m. — Professor Bottleneck and Shrimp City Slim
Location Fine Arts Center of Kershaw County 810 Lytlleton St., Camden, South Carolina 29020
Event Type Concerts & Live Music
Date & Time Oct 3, 2019 to Oct 5, 2019


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The Privacy Rights of Whistleblowers
The recent disclosures from Wikileaks have shown that the right to information, whistle-blowing, and privacy are interconnected. This note looks at the different ways in which the three are related, as well as looking at the benefits and drawbacks to Wikileaks in terms of privacy.
In a recent interview, the Canadian Privacy Commissioner was quoted as saying "Information and the manipulation of information is the key to power. Those who can control the information can influence society enormously." History and present-day society have both proven the truth in this statement. It is one among many reasons that the right to information is important to uphold. In India, and in other countries, there are statutes – in India, the Right To Information Act – that entitles the public to request and receive information that pertains to public bodies and their conduct, information that is publicly available because it is intrinsically related to the public interest. An entirely separate but equally critical way in which the public is kept informed is through whistle-blowing. Traditionally, whistle-blowing is any disclosure made in the name of public interest. Recent events such as the Ratan Tata case and the leaks of US diplomatic cables have brought to light the relationship between the public's right to information, the rights of whistleblowers, and the rights of individuals to privacy. These recent cases have shown that the right to information, whistle-blowing, and the right to privacy are interconnected, because privacy can provide individuals with the means to sustain autonomy against potentially overwhelming forces of government and persons who might have mixed motivations. The right to information and whistle-blowing are means by which the government is held accountable to the public if they violate the law or the public trust. The Wikileaks case and the Ratan Tata case raise important questions about when those two interests need to give way to private interests. One of the key questions that Wikileaks raises is: if whistleblowing is supposed to be disclosure in the public interest -- i.e., to protect the public – should disclosure of personal information be permissible only if a person can demonstrate that he/she is trying to remedy or avoid actual wrongdoing rather than simply publishing information that is "interesting to the public?"
What is a Whistleblower and how does a Whistleblower Benefit from Wikileaks?
Whistleblowing is the modern counterpart to "informers" – people who reveal others' wrongdoing. Much whistleblowing occurs by going "up the chain" in a person's own department or agency or company. If the person is reporting wrongdoing and the person ultimately goes to the authorities about illegal activity, the individual reporting the leak can sometimes get immunity for his or her own actions, can sometimes collect part of the penalties, and can under certain statutes in some countries even bring suit if the company retaliates against him -- for example, by firing him. In this way traditional whistleblowing places the responsibility for legal and ethical conduct on employees who are better situated to see wrongdoing than outsiders would be. In many countries, a person may present information of a whistleblowing nature to a judicial body. The judicial body then determines the validity of the information, the degree of public interest involved, and the proper form of redress to be taken. The judicial body offers legal protection to the whistleblower. Another method of whistleblowing is to leak information to the press. Once information is in the public domain – at least if there is freedom of press -- the information can no longer be covered up. Neither the right to free press, nor the right to protection as a whistleblower is universal. The current critique of the Indian Whistle Blowing Bill is that the right to protection will not be ensured. A Times of India article issued in September 2010 pointed out that the Whistle Blowing Act's biggest weakness is that the Bill's Central Vigilance Commission is designated to play both the role as competent authority to deal with complaints file by whistleblowers and as the tribunal to protect whistleblowers. Structuring the power to allow one body to fulfil both functions runs the risk of bias and could breed distrust that would cause people to avoid the system altogether. The article complained that the Bill has no teeth, and that even if the Commission believes that the whistleblowing is valid, it is able only to give advice rather than actually to prosecute individuals. The article recites extreme instances in which individuals have blown the whistle and paid for it with their lives. For example: in 2005 a manager of the Indian Oil Corporation was killed after exposing a scheme in adulterated petrol, and in 2010 an RTI activist was killed after exposing land scams in Mahrashtra. In these situations, Wikileaks is an interesting and powerful tool for individuals who either do not want to leak their information to a judicial body or are not protected if they do so in their own country. Leaking information to Wikileaks is in one sense analogous to leaking information to the press, but it is not precisely the same because it is not a news media outlet, but instead is a way for a person to post information on a mass media outlet. It should be noted, however, that informants who leak to Wikileaks are not afforded the same immunity that individuals who leak to authorities are granted. When an individual shares documents or information with Wikileaks, the site in turn acts as a platform to publish the information on the web and with the press. Being an independent entity that is neither tied down to a certain territory, government, or entity – Wikileaks has the pull of non-bias. But the strength of Wikileaks is also its weakness. When 250,000 diplomatic cables were posted, there was no one who understood the context of the content to monitor to ensure that everything was appropriate to post. As a result, the information was transmitted to an audience who normally would not be entitled to it. By doing so, the leaked information placed individual diplomats in precarious positions that could potentially put them in harm's way and unnecessarily damage their reputations, as well as putting the reputation of the United States on the line.
Privacy and Whistleblowing
As a result the United States is looking to press charges against Julian Assange, founder of Wikileaks, for espionage. The way in which Wikileaks leaked information and the nature of the leak has brought privacy into the picture. When looking at the act of whistleblowing through the lens of privacy, there are obvious privacy concerns for the whistleblower, for the person or entity whose information has been leaked, and for possible third parties involved. Paul Chadwick, the Victorian Privacy Commissioner, pointed out that for the whistleblower the main privacy concerns include the individual's identity, safety, and reputation. For the alleged wrongdoer the privacy concerns include: identity, safety, employment, and liberty (where sanctions may include imprisonment). For third parties, reputation and safety can both be jeopardized by disclosures by whistleblowers. The Wikileaks leaks squarely present the question whether intent should be brought into the analysis of privacy and whistleblowers. If a whistleblower is disclosing with the intent protect the public, the protections afforded to this person should weigh differently against the privacy interests of alleged wrongdoers and third parties than for someone who is simply defining the public interest as "interesting to the public," or, worse, as seen in the false leak by Pakistan against India, is looking to leak information to disrupt public interest. Even though Wikileaks works to protect the anonymity of individuals who leak information, it is not bound by any law to protect the privacy of individuals involved in the leak. The concept behind Wikileaks is important. By interacting with government information, it has the ability to bring accountability and transparency to governments, but the only regulation over Wikileaks is internal (and thus inherently subjective). Wikileaks needs to change its structure to take into account leaks shared without the intent of protecting the public interest and even then needs to monitor to prevent leaks that could place individuals in precarious situations or damage reputations with no validating information.
http://www.ctv.ca/generic/generated/static/business/article1833688.html
Chadwick, Paul. Whistleblowing, Transparency, and Privacy: Aspects of the relationship between Victoria's Whistleblowers Protection Act and the Information Privacy Act.
Filed under: Internet Governance, Privacy
The views and opinions expressed on this page are those of their individual authors. Unless the opposite is explicitly stated, or unless the opposite may be reasonably inferred, CIS does not subscribe to these views and opinions which belong to their individual authors. CIS does not accept any responsibility, legal or otherwise, for the views and opinions of these individual authors. For an official statement from CIS on a particular issue, please contact us directly.
Internet Governance, Privacy
Elonnai Hickok
The PDP Bill 2019 Through the Lens of Privacy by Design
The Wolf in Sheep's Clothing: Demanding your Data
Reclaiming AI Futures: Call for Contributions and Provocations
Comments to National Digital Health Mission: Health Data Management Policy
Mapping Web Censorship & Net Neutrality Violations
How to Shut Down Internet Shutdowns
Cybersecurity Visuals Media Handbook: Launch Event
Internet Speech: Perspectives on Regulation and Policy
SOTM Asia 2018
Workshop on Cybersecurity Illustrations
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We invite researchers, practitioners, artists, and theoreticians, both organisationally and as individuals, to engage with us on topics related internet and society, and improve our collective understanding of this field. To discuss such possibilities, please write to Amber Sinha, Executive Director, at amber[at]cis-india[dot]org or Sumandro Chattapadhyay, Director, at sumandro[at]cis-india[dot]org, with an indication of the form and the content of the collaboration you might be interested in.
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We are now only three weeks from race day, and it's time to start winding it down, at least in terms of volume! This is the part of the training programme where you'll have to test your 'faith' in the process!
If you've had a good few months, and been disciplined and diligent, done the necessary mileage, then you can enter these last few weeks with a perfect mindset that allows you to sharpen up. If you've had a patchy build-up, for reasons like injury, illness, work stress, then it's a little trickier, but we'll address that later. Let's first talk about the general concept of the taper period.
The idea behind the taper is that all the training you've done has challenged your body and physiology to adapt, to make you fitter, stronger, a better runner. But the key element that helps to 'unlock' that adaptation is recovery – you need to give the physiological systems a reprieve in order to allow full adaptation. And that's what the taper is doing.
You'll reduce volume, so have less time on your feet, but in turn will either slightly increase the intensity or keep it the same, so that you're still challenging yourself to run the necessary pace, but giving yourself the necessary opportunity to do so.
If it goes to plan, you should start to feel a "lightness" in your step, that your easy runs are suddenly easier than usual, that you have some bounce, that you're straining at the leash. At this point, it's really critical that you don't give in to this feeling of wanting to run harder, because then you'll just replace one stress (long runs, and volume) with another (hard runs and intensity). But the point is, as you drop the load, your body should thank you by feeling sharper, livelier, readier to race.
The challenge is getting it just right – if you taper too much, or for too long, then you can undo your fitness gains, because you'll be training less. Ideally, if you've trained well, then your base is solid enough that you should be able to afford about three weeks – one week to bring volume down, one week to nudge intensity up, and then a final week to really get sharp.
On the other, if your training hasn't quite gone to plan, and you feel a little underdone, then you should probably taper for two weeks, and rather make that third week out from race day a little more challenging. That's up to you, but irrespective, I'd advise that your last two weeks prioritize intensity and running at race pace or faster, and not volume.
The big temptation is to test yourself one last time, to do one final 16km "rehearsal" run for the half, or a 30km practice for the Ultra. Try to avoid that, and rather carry confidence and fresh legs into race day, even if it means a bit more doubts, rather than fatigue.


Walter Percy Chrysler, the founder of the American automotive corporation that bears his name, dies on this day in 1940 at his estate in Great Neck, New York, after suffering a cerebral hemorrhage. He was 65 years old.
Born in 1875 in Kansas, Chrysler was the son of a locomotive engineer; he began working himself when he was 17, earning seven cents an hour as an apprentice in a railroad machine shop. He worked his way up quickly, becoming a plant manager for the American Locomotive Company by the time he was 33 years old. In the early years of the automobile, Chrysler became fascinated: At a 1905 automobile show in Chicago, he borrowed $5,000 to purchase his own car, taking it apart and putting it back together again before taking a single ride. In 1911, Chrysler accepted a job as a manager at the Buick Motor Company at half his former salary. Within five years, he rose to become the company's president, and to make Buick into the strongest unit of William C. Durant's General Motors (GM).
Durant and Chrysler clashed over policy, however, and Chrysler left GM in 1920 to work with the Willys-Overland Company and with Maxwell Motors Company. A car designed by Chrysler and featuring a high-compression engine sold $50 million worth in its first year replaced the existing Maxwell car. In 1925, he emerged as president of the Chrysler Corporation, consisting of the former Maxwell and Chalmers car companies. After acquiring Dodge in 1928 and introducing the Plymouth that same year, the Chrysler Corporation would go on to become one of the Big Three of American automakers, alongside Ford and GM.
Aside from automobiles, Chrysler was chiefly known for financing the 77-story Art Deco skyscraper in midtown Manhattan (at the corner of Lexington Avenue and 42nd Street) that bears his name. To complete the distinctive ornamentation around the spire of the building, its architects used elements from Chrysler's automobiles, including radiator caps, hubcaps and stainless steel that evoked the chrome shine on a car. When it was completed in 1930, the Chrysler building was the tallest building in the world and the first manmade structure to top 1,000 feet. Surpassed by the Empire State Building a year later, the building remains one of New York City's most distinctive skyscrapers.


Our range of air compressors starts at 6 CFM up to 250 CFM. We supply small electric compressors mainly to the M&E industry for pipe testing, but also suitable to run small air tools and for spraying.
Our larger air compressors are mainly used in conjunction with air breakers and air picks which are suitable for breaking up areas of concrete. Mr Plant Hire class them as fast tow units and are supplied from a single tool unit up to a four tool unit and all are diesel driven.
Contact Mr Plant Hire to get a fast quote on hiring our Air Compressors and Air Tools in London, and nationally.


This stock music track turns domestic animals into wild ones with the amount of energy and amazing uplifting mood! It is an upbeat Rock track with catchy groove, bass guitar and juicy guitars! This track is perfect for your commercials, corporate and motivational projects, photo galleries, animations, sport you tube projects and more! This excellent piece of music will make your projects stand out like never before!


Cambridge International Advanced Subsidiary (AS) and Advanced (A) Level programs are designed for advanced academic students. They are available in 55 subjects and can lead to the award of a Cambridge Advanced International Certificate of Education (AICE) Diploma. The Cambridge AICE Diploma program was successfully piloted for three years in Florida where it continues to receive legislative support and funding.
This AICE Diploma helps higher education institutions identify students with the type of cohesive academic experience and higher-order thinking and communication skills that are associated with distinguished achievement at university.
* Check with the college or university of choice to determine the number of credits they will accept.
The Cambridge AICE Diploma is designed to deliver breadth across the curriculum and depth in selected subjects. Learners have to achieve a minimum of seven credits from at least three subject groupings and the core (Cambridge International AS Level Global Perspectives) to be awarded the diploma. Within the diploma a Cambridge International AS Level examination passing score is awarded one credit and a Cambridge International A Level examination passing score is awarded two credits.


In Berthiaume v. Smith, the Eleventh Circuit Court of Appeals held that jury members may be questioned during voir dire regarding latent bias predicated on sexual orientation. Relying on its decision in United States v. Bates and the United States Supreme Court's decision in Rosales-Lopez v. United States, the Eleventh Circuit concluded that, where matters of sexual orientation are "inextricably bound up" with the facts of the case, LGBT litigants are entitled to constitutional protections against jury bias.
To learn more about NAPD's involvement in the case and for the full text of David's summary, please visit the National Association for Public Defense.
After eight years of historic progress and support from the Obama Administration in almost all aspects of the law, from removing barriers to marriage equality and military service, to protecting LGBTQ persons at work and in school, we confront a new President, chosen after one of the most bitter and divisive elections in modern history. Does President Trump's ascension to the White House mean this progress will be reversed or stalled – even if America's hearts and minds already are evolving in favor of LGBTQ equality? Hard to say, given the mixed messages first from Candidate and now President Trump. What's clear is that much work remains ahead.


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Das Daytona 200 ist ein über 68 Runden dauerndes und 322 km langes Motorrad-Rennen. Es wird jährlich auf dem Daytona International Speedway in Daytona Beach, Florida ausgetragen.

Geschichte

Das Rennen entwickelte sich von einem 3,2-Meilen-Strandrennen (Daytona Beach Road Course) 1937 zu einem 2-Meilen-Rennen auf dem Daytona International Speedway 1961.

Aufgrund des wachsenden Interesses für Geschwindigkeit und den Umbau der NASCAR-Strecke nach der Saison 2004 nahmen die Daytona-Veranstalter zwei Änderungen für das Rennen 2005 vor. Zuerst wurde das Rennen der Serie Premiers AMA Superbike von 200 Meilen (322 Kilometer) auf 62 Meilen (100 Kilometer) gekürzt und ein Rennen der Serie Formula Xtreme eingeführt. Zudem wurde die Streckenführung geändert. Durch diesen Umbau wurde die Gesamtstrecke des Daytona 200 um eine halbe Meile gekürzt. 2009 eröffnet das Rennen der Daytona SportBikes die Veranstaltung. Diese Rennserie folgt durch den Verkauf der AMA Pro-Serie an Daytona Motorsports am 7. März 2008.

Das Daytona 200 ist eines der am stärksten frequentierten Motorradrennen in Amerika. Neun FIM-Weltmeister, darunter sieben Weltmeister der 500-cm³- bzw. MotoGP-Klasse, konnten es bisher gewinnen. Von den amerikanischen Meistern der letzten Jahre konnte nur Kenny Roberts jr. das Daytona 200 bislang nicht gewinnen. In den niedrigeren Kategorien gewannen unter anderem auch finnische und venezolanische Weltmeister.

Scott Russell und Miguel Duhamel haben mit je fünf Siegen die meisten Titel beim Daytona 200 erzielt. Russel ist deshalb auch als Mr. Daytona bekannt, da er alle Rennen in der Superbike-Klasse (750–1000 cm³) gewinnen konnte. Seinen fünften Sieg erreichte er in der 2005 neu eingeführten Rennklasse Formula Xtreme (600 cm³).

Der von Steve Rapp 2007 erreichte Sieg war der erste für Kawasaki seit 1995 und der erste Sieg für einen Nicht-Werksfahrer seit John Ashmead 1989.

Sieger

Siehe auch
 Daytona Beach Bike Week

Weblinks

 Daytona International Speedway (englisch)

Einzelnachweise

Motorradrennen
Motorsportwettbewerb in den Vereinigten Staaten
Sportveranstaltung in Daytona Beach
Erstveranstaltung 1937

redpajama_set_name: RedPajamaWikipedia


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Fans lined up for blocks to get into Rhode Island Comic Con per usual and this year certainly didn`t disappoint. It all kicked off on Thursday evening at the Cinemas at Providence Place Mall with a special viewing of A Nightmare on Elm street. What`s better than watching a horror classic on Halloween night you ask? Watching the movie with Freddy himself Robert Englund is the correct answer and that`s exactly the opportunity that fans had!
Doors opened at 3:00pm on Friday to the masses and they filled in quickly. To our surprise, there was no ribbon cutting ceremony for the first time in many years. Day one ran from 3:00pm-9:00pm and fans had the opportunity to attend some great Q&A panels, visit the KIDS ZONE upstairs on the 5th floor of the Convention Center as well as meet their favorite celebrities.
This year featured some great groups of talent including cast members from National Lampoon`s Christmas Vacation such as Chevy Chase, Beverly D`Angelo, Dana Barron and Anthony Michael Hall. Also featured through out the weekend were members of the Family Matters cast including Jaleel White, Kellie Williams, Darius McCrary and Shawn Harrison. Several cast members from the hit Netflix show Stranger Things were also on hand. Any Star Trek fans out there?! Star Trek fans were treated to the presence of William Shatner, George Takei and Nichelle Nichols among others.
Lines for the celebrities ran smoothly and it was great to witness fans meeting their idols in person for the first time. The celebs were spread out this year to avoid too much congestion and it seemed to work out great. There were dozens of celebs on the 5th floor of the Rhode Island Convention Center and that`s where a lot of the focus was this year. There was also a smaller celeb area on the 3rd floor of the Rhode Island Convention Center which featured another 30 celebrities or so. The arena floor of the Dunkin Donuts Center was also filled with some of the major celebs that were in attendance.
Cosplay is always such a huge deal at these events and fans certainly didn`t disappoint this year. Fans came from all over the world, dressed as their favorite characters. There were merchandise vendors from all over the United States, giving fans tons of options in the way of weekend purchases and those looking to complete or start their collections! Day two (Saturday) ran from 10:00am-7:00pm with doors opening at 9:00am for VIP`s. Saturday is always the busiest day and boy was the crowd out in full force.


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HomeThe Duke of CambridgeKensington Palace Announced The New School of the Cambridge Siblings in Berkshire
Kensington Palace Announced The New School of the Cambridge Siblings in Berkshire
The announcement of Kensington Palace, Monday morning, that Prince George, Princess Charlotte, and Prince Louis are enrolled at Lambrook School in Berkshire, finally confirmed the speculation that the Duke and Duchess of Cambridge are moving with their children to Adelaide Cottage near Windsor Castle in Berkshire.
The announcement came days after Buckingham Palace announced that Lady Louise Windsor will attend The University of St. Andrews in Scotland, the alma mater of the Duke and Duchess of Cambridge.
The Cambridge family during The Queen's Platinum Jubilee week. Getty Images
It has long been speculated that Prince William's family will be moving to Adelaide Cottage to live near The Queen, but no confirmation has been given by Kensington Palace. The couple, however, will maintain Kensington Palace as their London home and will use Anmer Hall in Norfolk as their country home.
Kensington Palace Announcement:
"The Duke and Duchess of Cambridge have today announced that Prince George, Princess Charlotte, and Prince Louis will attend Lambrook School in Berkshire from September 2022.
"Their Royal Highnesses are hugely grateful to Thomas's Battersea where George and Charlotte have had a happy start to their education since 2017 and 2019 respectively and are pleased to have found a school for all three of their children that shares a similar ethos and values to Thomas's."
Jonathan Perry, the headmaster at Lambrook School, said: "We are delighted that Prince George, Princess Charlotte, and Prince Louis will be joining us this coming September and very much look forward to welcoming the family, as well as all of our new pupils, to our school community."
Lambrook School
Lambrook, a Christian school in Berkshire, prides itself on its high academic standards, with a pass rate of 100 percent for the Common Entrance exam
According to its website, Lambrook School is a leading co-educational Prep School for 615 boys and girls aged 3-13, set on 52 acres of beautiful Berkshire countryside.
Lambrook School in Berkshire. Credit: Lambrook School
The school was founded in 1860 and boasted a royal connection. Two of its previous pupils in the 19th century were grandsons of Queen Victoria.
Prince Christian Victor and Prince Albert of Schleswig-Holstein. They were sons of Queen Victoria's daughter, Princess Helena, who married Prince Christian of Schleswig-Holstein.
According to Lambrook history, "Queen Victoria used to travel from Windsor Castle to Lambrook School to watch her grandsons play in cricket matches".
The school offers impressive sports facilities and the Cambridge children will surely enjoy activities such as bee-keeping and scuba diving. The school also hosts Harry Potter evenings.
Fees cost £4,389 a term for Reception to Year 2 pupils such as Louis, £6,448 per term for Years 3-4 like Charlotte, and £6,999 per term for George through Years 5-8, with an additional £1,481 per term for boarding for Y3-8.
It means the Duke and Duchess of Cambridge will be spending in excess of £50,000 a year on their children's private education.
However, Lambrook School, with almost 620 pupils, is considered a larger than average pre-prep and prep school in England but billed as not as pushy as its London counterparts.
It is expected Prince George, Princess Charlotte, and Prince Louis will attend a day school set up this school year. Lambrook is also a private boarding school.
Lambrook School in Berkshire
Lambrook School is just a 15-minute drive away from Adelaide Cottage. And has a relaxing countryside atmosphere for its pupils. It has 52 acres of beautiful grounds and an Orchard with top-notch facilities.
It has woodland, a nine-hole golf course, and endless sports pitches, a 5-meter swimming pool, Astroturf, Hard Courts, a Diamond Jubilee Performing Arts Studio, Dance Studio, and Sports Hall.
It's indeed a remarkable environment for academic learning, Art, Design & Technology, and the Performing Arts, and children will have plenty of opportunities to explore, play, learn and have fun with other kids.
According to The Telegraph: "The Duke and Duchess of Cambridge hope the move will allow them to give their children the best and most 'normal' childhood possible.
It will also ensure stability if they relocate next door to Windsor Castle at any point in the future. It has enabled the Duke and Duchess to enroll their children at a co-educational Berkshire prep school set in extensive grounds and boasting impressive on-site sports facilities."
It has been reported that Prince George had a trial day at Lambrook School in April this year, and the teachers arranged a settling-in style trial class for the eight-year-old heir to the throne.
The Duke and Duchess of Cambridge had visited the school multiple times prior to The Queen's Jubilee celebration. The couple planned to have all three of their children at the same co-educational establishment.
The Cambridges are expected to move to Adelaide Cottage next month.
The Duke of Cambridge


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/ Featured Cities / American Mecca, Salt Lake City – Episode 205
American Mecca, Salt Lake City – Episode 205
See the history of the American Midwest and the beauty Salt Lake City has to offer.
Joe Dorsey on November 18, 2013 - 7:38 pm in Featured Cities, Historical, Places to visit
Searching for some things to do in Salt Lake City? We get that a lot because there's so many possibilities in SLC. There's unbelievable natural beauty surrounding and throughout Salt Lake. And that beauty allows for endless outdoor recreation, any time of year. And then, of course, Salt Lake is the worldwide headquarters of the Church of Jesus Christ of Latter-Day Saints…or Mormons. Still stumped? Then look through some of the options below – we're sure there'll be something to pique the interest of a history and travel lover.
The Great Salt Lake
As the largest natural lake west of the Mississippi River and the largest salt water lake in the western hemisphere, the Great Salt Lake is perhaps the best known geologic feature in the area. The city even takes its name from the lake – originally it was Great Salt Lake City, but the "Great" was dropped from the name in 1868. The lake has a rich history, interesting features, plays an important role in the ecosystem and provides abundant recreational opportunities. More Info.
Great Salt Lake
Cycling In Salt Lake
One of the most happening cycling scenes in the nation is right here in the Beehive State's capital, Salt Lake. From skinny tires to fat, from townies to fixies, Salt Lake offers an incredible array of biking options.
When the famed "Greatest Snow On Earth" starts to melt from the Wasatch, small and not-so-small two-wheeled armies start invading the trails, streets, paths and hills in and around Salt Lake. Here, in no particular order or hierarchy, is a breakdown of the more noticeable and mainstream cycling options for the hard-core to the casual commuter. More Info.
Visiting Temple Square
Historic Temple Square and the headquarters of the Church of Jesus Christ of Latter-day Saints (Mormons) are located in the heart of downtown Salt Lake City. Just four days after arriving in the Salt Lake valley following an arduous trek across the Great Plains, Mormon pioneers designated the location where they would build their church's first temple in this valley.
Although the Salt Lake Temple took 40 years to complete once ground was broken, the area surrounding the temple became the center of the city, with activity at the Tabernacle and ongoing construction on the temple. Addresses throughout the valley reflect the idea of Temple Square being the center of the city as they indicate how many blocks north, south, east or west an address is from that specific location. More Info.
Other things to do in Salt Lake City
If you want to stand exactly where Brigham Young declared "This is the place, drive on," then head to This is the Place State Park. There you'll see how the Mormon pioneers settled the land and lived during the 19th century. Also, be sure to check out the Natural History Museum of Utah. This state-of-the-art museum features thousands of dinosaur fossils discovered locally in Utah. The collection is awe inspiring. Don't miss the triceratops wall. If you love aviation, head to the Hill Aerospace Museum. This working Air Force base has an extensive collection of US aircraft from a replica Wright Brother's flyer to the SR71 Blackbird.
Natural History Museum of Utah Dinosaur
For more information on things to do in Salt Lake City, Utah for a history inspired visit go to www.visitsaltlakecity.com
Photos courtesy of Dollar Photo Club & Wikimedia Commons
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ONCOLOGY Vol 21 No 9 | Oncology
Updated Study Results Reinforce Survival Benefit of Docetaxel for Men With Advanced, Hormone-Resistant Prostate Cancer
Docetaxel (Taxotere)-based chemotherapy (with prednisone) maintained long-term efficacy as a treatment for advanced (metastatic) hormone-resistant prostate cancer patients, according to the 3-year updated results of the landmark TAX 327 study.
Gene Variations Directly Link Inflammation to an Increased Risk for Lung Cancer
Variations in two genes related to inflammation may be a major risk factor for developing lung cancer, according to a team of scientists from the National Cancer Institute and the University of Texas
ODAC Recommends Approval of Raloxifene to Reduce Risk of Invasive Breast Cancer
Eli Lilly and Co announced that the Oncologic Drugs Advisory Committee of the US Food and Drug Administration (FDA) voted to recommend approval of its osteoporosis drug raloxifene (Evista) for a new use, to reduce invasive breast cancer risk in two populations: postmenopausal women with osteoporosis and postmenopausal women at high risk for breast cancer.
Liposomal Doxorubicin Delays Time to Disease Progression as Maintenance Therapy in Patients With Metastatic Breast Cancer
Schering-Plough Corp announced results from a phase III study that showed maintenance chemotherapy with pegylated liposomal doxorubicin hydrochloride (Doxil, marketed in Canada and Europe as Caelyx) significantly prolonged time to progression (TTP) in patients with metastatic breast cancer with infrequent and manageable clinical toxicity after first-line chemotherapy.
Advisory Committee Recommends FDA Wait for Satraplatin Survival Results
GPC Biotech announced that the Oncologic Drugs Advisory Committee (ODAC) for the US Food and Drug Administration (FDA) recommended (12–0) that the FDA should wait for the final survival analysis of the SPARC trial before deciding whether satraplatin is approvable for the treatment of hormone-refractory prostate cancer patients whose prior chemotherapy has failed.
New Complementary Medicine Guidelines Available From Society of Integrative Oncology
The Society for Integrative Oncology (SIO), an international organization established in 2003 to encourage scientific evaluation, dissemination of evidence-based information, and appropriate clinical integration of complementary therapies, recently issued practice guidelines regarding the use of nonconventional treatment modalities
Skin Rash Actually Signifies Better Outcomes for Pancreatic and Lung Cancer Patients
The appearance of a rash in cancer patients treated with erlotinib (Tarceva) is strongly associated with longer survival, according to researchers from the drug's developer, OSI Pharmaceuticals
Red Wine Protects the Prostate, Seattle Investigators Report
Researchers have found that men who drink an average of four to seven glasses of red wine per week are only 52% as likely to be diagnosed with prostate cancer as those who do not drink red wine
Lenalidomide Data in Multiple Myeloma Patients Demonstrate Impressive Survival Benefit
lenalidomide (Revlimid) with reduced doses of the steroid dexamethasone in the treatment of multiple myeloma.
Key Developments in Rectal Cancer Treatment
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor (VEGF) are often overexpressed in colorectal cancer and are associated with inferior outcomes. Based on successful randomized phase III trials, anti-EGFR and anti-VEGF therapeutics have entered clinical practice. Cetuximab (Erbitux), an EGFR-specific antibody, is currently approved in the United States in combination with irinotecan (Camptosar) for patients with metastatic colorectal cancer refractory to irinotecan or as a single agent for patients unable to tolerate irinotecan-based therapy. In retrospective analyses, patients with EGFR-expressing rectal cancer undergoing neoadjuvant radiation therapy had a significantly inferior disease-free survival and lower rates of achieving pathologic complete response. Based on the positive data in metastatic colorectal cancer and synergy with radiation therapy seen in preclinical models, there is a strong rationale to combine cetuximab with neoadjuvant radiation therapy and chemotherapy in rectal cancer. Bevacizumab (Avastin), a VEGF-specific antibody, was the first antiangiogenic agent to be approved in the United States for use in combination with standard chemotherapy in the first- and second-line of treatment in metastatic colorectal cancer. VEGF-targeted therapy may lead to indirect killing of cancer cells by damaging tumor blood vessels, and may increase the radiosensitivity of tumor-associated endothelial cells. VEGF blockade can also "normalize" tumor vasculature, thereby leading to greater tumor oxygenation and drug penetration. This review will address completed and ongoing trials that have established and continue to clarify the effects of these agents in rectal cancer.
Role of Stem Cell Transplant in Pediatric Cancers
In the June issue of ONCOLOGY, authors McGregor et al did an admirable job of reviewing childhood cancer advances and current issues in their article entitled "Pediatric Cancers in the New Millennium: Dramatic Progress, New Challenges"
Curing Gastric Cancer: Steps in the Right Direction But Miles to Go
The majority of patients who undergo resection for gastric cancer experience relapse and ultimately die of their disease. Therefore, considerable attention has been paid to neoadjuvant and adjuvant strategies to improve surgical outcomes. Two different approaches have been tested in major clinical trials conducted in the past several years: Postoperative chemoradiotherapy was assessed in a US Southwest Oncology Group/Intergroup study (SWOG 9008/INT 0116), and perioperative chemotherapy was studied in a UK Medical Research Council (MRC) randomized trial (the MRC Adjuvant Gastric Infusional Chemotherapy [MAGIC] trial). These trials demonstrated statistically significant survival benefits in patients with resectable gastric cancer. This review will consider these trials and their implications for clinical practice.
Hepatocellular Carcinoma: Neoadjuvant Therapy Reconsidered
Hepatocellular carcinoma (HCC) is an aggressive tumor that often occurs in the setting of chronic liver disease and cirrhosis. The incidence of hepatocellular carcinoma is increasing in the United States and worldwide. Orthotopic liver transplantation (OLT) is a viable and potentially curative option for selected patients with HCC. Locoregional therapy has been used to control HCC before transplantation because of the limited number of donor organs, to prevent tumor progression, and to decrease the incidence of dropouts from the transplant waiting list. Traditionally, multiple investigational locoregional modalities such as tumor resection, radiofrequency ablation, transarterial chemoembolization, and systemic chemotherapy have been used as "bridging" therapies. While the investigation of novel neoadjuvant treatments is justified in an effort to prevent tumor progression, the absence of randomized controlled trials leaves uncertainty about the utility of these maneuvers in improving outcome. This review summarizes the current data on the different modalities used worldwide in the neoadjuvant treatment of hepatocellular carcinoma, the rationale for these approaches, efficacy, potential complications, and future prospects.
Integrins in Cancer: Novel Therapeutic Approaches
The integrins are a family of transmembrane receptors important for the cell-cell and cell-matrix interactions that relate to processes of cell adhesion, migration, invasion, angiogenesis, and survival.
Honing Therapy for Rectal Cancer
Gastric Cancer: Are There New Therapeutic Options?
Hepatocellular Carcinoma Patients Awaiting Transplant: General Guidelines for Management
The Role of Integrins in Colorectal Cancer
Integrins have direct effects in stimulating proliferation and preventing apoptosis in cancer cells and mediating proangiogenic interactions between endothelial cells and extracellular matrix. Alterations of expression of various integrins and their receptors have been observed in various cancers in which angiogenesis is known to play a role, including colorectal cancer. Inhibition of specific integrins might thus inhibit both direct effects of integrins on cancer cells and tumor angiogenesis. Inhibitory peptides and anti-integrin monoclonal antibodies are currently being investigated in clinical trials in patients with solid tumors, with early evidence suggesting clinical benefit in disease stabilization with use of an anti-αvβ3 antibody in the settings of colorectal cancer, renal cell carcinoma, and melanoma. Integrin inhibition alone and with other targeted therapeutic approaches should be further investigated in clinical trials in patients with colorectal cancer.
The Biology of Integrins
Adhesion molecules have traditionally been thought of simply as receptors that permit anchorage to other cells or to the underlying extracellular matrix (ECM). However, within the past decade it has become apparent that adhesion molecules such as integrins mediate critical cytosolic signaling events that have a dramatic impact upon cell proliferation, survival, and motility. Integrins act to regulate both physiologic and pathologic events, including complex processes such as angiogenesis, tumor growth, and metastasis. For these reasons, integrins have become attractive targets for drug development, and several effective integrin antagonists are now under clinical evaluation. In turn, the use of integrin-targeted reagents has provided additional mechanistic insights into the workings of the receptor. In particular, it has become apparent that integrins are "mechanosensory" receptors that operate in a context-dependent manner. While integrins that ligate substrate-immobilized ligands typically transduce positive signals into the cell, antagonized or unligated integrins promote negative signaling into the cell, leading to cell cycle arrest or apoptosis. Thus, integrins appear to fulfill a biosensor function, wherein they constantly interrogate the local ECM, and modulate cell behavior accordingly. These new roles that integrins play reinforce the choice of integrins as a therapeutic target, even as they lead us to reassess and optimize current clinical strategies.
Targeted Therapy in Rectal Cancer
Non-Hodgkin's Lymphoma in the Elderly (Part 1: Overview and Treatment of Follicular Lymphoma)
Non-Hodgkin's lymphoma is one of a few malignancies that have been increasing in incidence over the past several decades. Likewise, these disorders are more common in elderly patients, with a median age of occurrence of 65 years. Therapy in elderly patients may be affected by multiple factors, especially attendant comorbidities. The approaches to management of these patients, with either indolent or aggressive disease processes, have been based on prospective clinical trial results, many of which have included a younger patient population. Fortunately, over the past decade, results of treatment trials that have targeted an older patient population have emerged. The disease incidence and treatment approaches for both follicular (part 1 of this article) and diffuse aggressive (part 2) histologies in elderly patients are reviewed, as well as the impact of aging on the care of these patients.
Therapeutic Options in Gastric Cancer: Neoadjuvant Chemotherapy vs Postoperative Chemoradiotherapy
Problem-Related Distress in Cancer Patients Drives Requests for Help: A Prospective Study
The Moores UCSD Cancer Center has implemented the use of an innovative instrument for screening cancer patients at first visit to assist them with distress due to cancer-related problems. This 36-question screening instrument addresses physical, practical, social, psychological and spiritual problems. Patients are asked to rate the severity of each problem on a scale of 1 to 5, and to circle "Yes" if they would like staff assistance. Data from a prospective study of the first 2,071 patients to complete this questionnaire has been entered into a database and analyzed to identify common patient problems, demographics, and trends. The five most common causes of problem-related distress were fatigue, sleeping, finances, pain, and controlling my fear and worry about the future. The five most common problems for which patients circled "Yes" to ask for assistance were understanding my treatment options, fatigue, sleeping, pain, and finances. Compared to the entire population, patients who circled "Yes" on a particular problem, demonstrated a robust increase in problem-related distress.
Neoadjuvant Therapy for Hepatocellular Carcinoma: Is There An Optimal Approach?
Integrins and Cancer
Integrins play an important physiologic role in cell adhesion, and accumulating evidence suggests that they also regulate cell growth, proliferation, migration, and apoptosis. A number of congenital and acquired disease states have been associated with integrins, and small- molecule integrin inhibitors have been approved for treatment of benign hematologic diseases. In cancer, aberrant expression with normal functioning rather than dominant genetic variations of genes coding for integrins has generally been observed. This aberrant expression is mediated through "bidirectional" receptor signaling and interaction with corresponding signals from growth factor signaling pathways, leading to inhibition of apoptosis, induction of cell proliferation, extracellular matrix remodeling, migration, and angiogenesis. From a clinical perspective, a growing number of molecules targeting integrins have been developed for treatment and imaging purposes; clinical studies in melanoma, prostate cancer, and other malignancies are underway. This review summarizes the biology of integrins, the signal transduction pathways they regulate, and their role in different stages of carcinogenesis. Furthermore, it provides a synopsis on the clinical advancements in integrin targeting for therapeutic and imaging purposes in cancer.
Cancer Management: A Multidisciplinary Approach
The fundamental principle behind this book, as stated by the publisher, The Oncology Group (also publisher of the journal ONCOLOGY and news magazine Oncology News International) was to provide a truly integrated, multidisciplinary approach to the management of cancer patients. For this updated 10th edition, the editors have enlisted 114 medical, surgical, and radiation oncologists, whose contributions provide an excellent overview of the important principles of cancer management.