Interstate 465 (I-465), also known as the USS Indianapolis Memorial Highway, is the beltway circling Indianapolis, Indiana, United States. It is roughly rectangular in shape and has a perimeter of approximately 53 miles (85 km). It lies almost completely within the boundaries of Marion County, except for two short sections on the north leg in Boone and Hamilton Counties. It intersects with I-65, I-69, I-70, and I-74, and provides additional access to I-65 via I-865.
The approximately one-mile section between exits 46 and 47 upon completion of the Interstate 69 extension will carry nine routes — I-465, I-69, US 31, US 36, US 40, US 52, US 421, SR 37 and SR 67. In most cases, markers other than I-74's are not posted along I-465 itself; rather, signs on the entrance ramps direct traffic traveling a particular route to follow I-465 to a specific exit to continue on that route.
A beltway for Indianapolis was part of the original plan of the Interstate System in 1955. The general alignment was to be either on or adjacent to the now-defunct State Road 100, which by then had only two completed legs—on the north side, along 86th Street west of the White River and 82nd Street east of the river, and on the east side along Shadeland Avenue. On the city's west side, an alignment corridor paralleling High School Road was preferred, and on the south side, one between Hanna Avenue and Thompson Road had been proposed. Development along 86th Street made its use unfeasible for I-465, so a 91st Street alignment was initially proposed. This proved to be controversial, and caused many delays in final alignment selection for the north leg, postponing its construction by several years.
The I-465 beltway was constructed in segments. There were 16 segments along the original proposed semi-circumferential alignment between I-65 in Boone County at exit 129 and that same highway six miles (9.7 km)six to the south at exit 123 in Marion County. Indiana highway officials recognized the value of having the route be a full circumferential, so using non-Interstate federal funding and employing a temporary designation of SR 100, they planned a separate 17th segment northward between I-65 at its exit 123 and the north leg of I-465 in Boone County. By the time that added section was completed in 1970, Indiana had obtained federal approval to sign it as I-465 as well, resulting in the creation of a dogleg section of I-465 outside of the loop (now signed as I-865).
State highway officials concentrated on building the west and south legs of I-465 early in the overall project, since they were the missing portions of the SR 100 concept. Construction began in 1959, and the first section of the I-465 beltway to be completed was the portion on the west leg between I-65 near Eagle Creek Park and I-74/US 136 in Speedway. That section was opened to traffic on September 26, 1961, simultaneously with the adjacent section of I-65 northwest from there running 1.48 miles (2.38 km) to 71st Street. By July 18, 1962, all four segments of the original west leg were open between Kentucky Avenue (SR 67) and I-65, but the interchange with I-70 in that stretch was not completed until much later that decade when the segment of that route from I-465 west to SR 43 opened in 1968.
The south side sections were the next to be completed, with three opening in the second half of 1963 and two more on October 15, 1964. This completed both the south leg and the first segment of the east leg, and included a connection from a point just north of the Raymond Street grade separation to SR 100 (Shadeland Avenue) at Washington Street (US 40). With these sections open, the full length of I-74's concurrency over I-465 was now available for motorists. The south leg's junction with I-65 was also completed, but I-65 itself was open only between a temporary intersection at Thompson Road to the south and the Keystone Avenue interchange 1.18 miles (1.90 km) north of I-465 until early 1971.
With SR 100/Shadeland Avenue connected to the full southern and western bypass of Indianapolis, work on I-465's east leg slowed, delaying the opening of the next segment over three years. In January 1968 two sections of the east leg, between Pendleton Pike (US 36/SR 67) and the SR 100 junction near Raymond Street, were completed and opened a day apart. This allowed through traffic from both US 36 and SR 67 to bypass the increasingly congested SR 100. The interchange with I-70 in this newly opened section was not yet complete and its ramps did not open until the opening of that route's mainline between SR 100/Shadeland Avenue and SR 9 near Greenfield on December 2 of that year. On October 23, 1968, the section of I-465 between Pendleton Pike and 56th Street at Shadeland Avenue was finished and opened to traffic, completing the east leg's eastern bypass of SR 100.
With its alignment controversies now settled, the north leg of I-465 began to take shape in the late 1960s. The section between Michigan Road (US 421) and Meridian Street (US 31) was the first on this side of town to see traffic, on October 20, 1968. A year to the day later, the segment from US 31 to Keystone Avenue (then SR 431) was opened to motorists. The next month, in November 1969, the north extension of the west leg was completed and signed as I-465 (although it was considered to be "added mileage" by the Federal Highway Administration since it was built to Interstate standards using non-Interstate funds by Indiana), but only the portion between I-65 and 86th Street was opened to traffic because the segment of the north leg to which it would connect was not yet complete. That occurred on August 18, 1970, when the western end of the north leg between I-65 near Royalton and Michigan Road (US 421) was finished and opened to traffic. At that time the final connection on the north extension of the west leg to 86th Street was also opened, leaving only one remaining gap in the entire I-465 route.
The final section of I-465 to be built was the portion joining the north and east legs, between Keystone Avenue (then SR 431) and 56th Street at Shadeland Avenue (then SR 100). This stretch opened to traffic on October 5, 1970, and marked the completion of the I-465 beltway around Indianapolis.
The first of the major post-completion rebuild and expansion projects occurred from 1999 to 2002, when the heavily-traveled northern section of the east leg was modernized and expanded to as many as 13 lanes in one short portion. Concurrently, the east junction with I-70 was rebuilt and reconfigured. In 2000, the Emerson Avenue interchange on the south leg was converted from a conventional diamond to a single-point urban interchange, becoming the first SPUI on the I-465 beltway.
Between 2004 and 2005, the north extension of I-465's west leg between I-65 and I-865 was rebuilt to widen and update the freeway in this heavily-traveled section located along the western edge of the massive Park 100 commercial and industrial development. This segment was rapidly becoming functionally obsolete due to continued growth of that complex as well as that of other nearby residential and commercial projects in Pike Township. Both interchanges along this stretch, 71st Street (exit 21) and 86th Street (exit 23), were totally rebuilt while remaining open to traffic, and had loop ramps added for west-to-south movements. In addition, a new northbound exit ramp was added at exit 21 which bridges over 71st Street to directly deposit motorists onto eastbound 73rd Street. On the mainline, dual auxiliary lanes were added in each travel direction between these interchanges and the 79th Street grade separation over I-465 was demolished and rebuilt to allow for the widened freeway below. Distinctive decorative features were also incorporated into most of the grade separation structures within this project. Also, bicycle paths were established along the southern side of both 86th and 71st Streets, which included grade separations with the east-to-south ramps at both interchanges.
In April 2002, INDOT announced the redesignation of the dogleg portion of I-465 as I-865. This change eliminated the three-way intersection of I-465 where the north extension of the west leg met the original north leg (at exit 25).
INDOT completed an $800 million project called Accelerate 465 to refurbish and reconfigure the original west leg of the loop between July 2007 and December 2012. This project completely rebuilt and added new travel lanes, added auxiliary lanes, rebuilt many grade separations, and reconfigured nearly all of the interchanges along I-465 from just north of the Kentucky Avenue (SR 67 south) interchange to the 56th Street partial interchange. The junction with I-74 and Crawfordsville Road (US 136 west) was reconfigured to allow direct access between I-465 and US 136 for the first time. Interlaced into that design is a full directional connection for I-74, which replaced the former cloverleaf interchange and removed its original stub connector east of I-465 to the intersection of Crawfordsville Road and High School Road in Speedway.
Also in 2007, another undertaking was launched by INDOT to modernize the entire northeastern portion of I-465. All three interchanges along the freeway in this stretch—Keystone Avenue (exit 33), Allisonville Road (exit 35) and I-69/Binford Boulevard (exit 37)—were to be modified and rebuilt. As this project progressed, financial constraints prompted INDOT to scale back its scope. The reconstruction of I-465 between the White River bridge and Fall Creek, including the interchange with I-69, is not scheduled to begin until 2022 under a separate project announced in 2015 and formally re-launched as "Clear Path 465" in 2017. The original, scaled-back project concluded by the end of 2012. The beltway's mainline was reconstructed with additional travel and auxiliary lanes being added in two separate segments—from east of Meridian Street to Allisonville Road, and from a point at the southeast end of the I-69/Binford interchange southward to Fall Creek. The Keystone Avenue parclo interchange was reconfigured to allow free-flowing access. At Allisonville Road, the interchange was converted into a more efficient SPUI configuration. Finally, though the interchange itself was not rebuilt, the I-69/Binford Boulevard junction had two ramps slightly modified to facilitate better traffic flow.
As part of the major project to upgrade 13 miles (21 km) of US 31 in Hamilton County to a full Interstate-standard freeway, the I-465 north leg interchange at Meridian Street (exit 31) was reconfigured between October 2013 and December 2015 (with some additional work continuing until November 22, 2016) to the present partial directional (system interchange) design which allows for free-flow movements to or from the new US 31 freeway to the north.
As part of its Operation Indy Commute project, INDOT began work in 2013 to widen I-65 on both its northbound and southbound mainlines from exit 103 at Southport Road northward to the junction with I-465's south leg, which would also be modified. To reduce congestion at and near that interchange, the loop ramp from westbound I-465 to southbound I-65 was replaced by a flyover ramp. The eastbound I-465 exit to southbound I-65 was also expanded for smoother merging with the new west-to-south flyover. In addition, grade separations over I-465 were replaced on Sherman Drive and Carson Avenue to allow for longer and wider approaches to this busy junction. Most of this work was completed in late 2014.
In 2002, Indianapolis native David Letterman's late-night talk show sidekick and band leader Paul Shaffer was honored by having a street in Thunder Bay, Ontario, named for him. This led Letterman to ask (on his program) why he couldn't have his own eponymous road, and he suggested I-465 be named the David Letterman Expressway (sic). His fans took the idea seriously, especially in the Indianapolis area where highway signs promoting the idea were displayed. Advertisers and a few traffic reports started to refer to I-465 as the "DLX", or later the "David Letterman Bypass", a reference to his quintuple heart bypass surgery in January 2000. Letterman even telephoned the Mayor of Indianapolis, Bart Peterson to make his case, but eventually the idea went nowhere.
In 2011 the Indiana General Assembly passed a resolution officially designating I-465 as "USS Indianapolis Memorial Highway" in "the memory of the brave sailors who lost their lives" when USS Indianapolis was sunk in the Pacific during World War II. Signs for this designation have been erected sporadically around the loop, but the highway is still referred to nearly exclusively as "I-465" or simply "465" by most locals.
Upon completion of I-69 between Martinsville and I-465, I-69 is expected to be signed concurrently on I-465 around its south and east legs in Indianapolis—between the new exit 5 for I-69 and SR 37 south on the southwest side and existing exit 37 for I-69 and SR 37 north in the northeast neighborhood of Castleton..
Remaining sections of the I-465 beltway that are still awaiting reconstruction or widening projects include the west leg junction with I-65, the north leg between I-865 and US 31 North/Meridian Street, the north leg section from Allisonville Road to the I-69/Binford Boulevard interchange and several portions along the south leg.
31.87 20 I-65 – Indianapolis, Gary, Chicago I-65 exit 123; directional access (northbound to northbound and southbound to southbound) only.
69.89 44 I-70 – Indianapolis, Dayton I-70 east exit 89, west exit 90. Signed as exits 44A (east) & 44B (west) northbound.
84.96 53 I-65 – Indianapolis, Louisville I-65 exit 106; signed as exits 53A (north) & 53B (south).
^ a b Reference Post Book (PDF). Indianapolis: Indiana Department of Transportation. 2004. I-465. Archived from the original (PDF) on June 15, 2011.
^ "USGS 1984 map". Retrieved October 5, 2014.
^ Indiana Department of Transportation (April 24, 2002). "Indiana's 'New' Interstate: I-865" (Press release). Indiana Department of Transportation. Retrieved December 5, 2016.
^ a b "INDOT Reveals Plans for Major Construction on I-465 & I-69". Indianapolis: WISH-TV. October 24, 2007. Archived from the original on May 14, 2008.
^ "State to Invest $50 Million to Improve I-465/I-69 Interchange on Indy's Northeast Side" (Press release). Indiana Department of Transportation. December 29, 2015. Retrieved December 8, 2016.
^ "Clear Path 465 (Interstate 465 & 69 Northeast)". Indiana Department of Transportation. Retrieved July 17, 2018.
^ "Operation Indy Commute: I-65 & I-465 South". Indiana Department of Transportation.
^ "I-465 gets new name". Indianapolis Star. Retrieved October 5, 2014.


text:
Tide Turning Against Plastic Microbeads in Toiletries
by Source on May 4, 2015 · 0 comments
in Culture, Economy, Environment
By Sarah "Steve" Mosko / Boogie Green
There are signs that the era where plastic microbeads from personal care products pollute bodies of water worldwide and aquatic food chains might be drawing to a close.
Microbeads are miniscule spheres of plastic commonly added as abrasives to personal care products like face scrubs, shower gels and toothpaste. They're designed to wash down the drain, but because of their small size, they escape sewage treatment plants. Once discharged into oceans, rivers or lakes or onto land, they're virtually impossible to clean up.
They're typically made of polyethylene or polypropylene and do not biodegrade within any meaningful human time scale, especially in aquatic environments. And, like other plastics, they attract and accumulate oily toxins commonly found in bodies of water (e.g. DDT, PCBs and flame retardants).
Microbeads resemble fish eggs, likely contributing to the documented ingestion of microplastics in the millimeter and under size range by sea life in bottom tiers of the ocean food web, including zooplankton, sandworms, barnacles and small crustaceans. The potential for ingested microplastics to transfer up aquatic food chains is very real, as demonstrated by studies revealing transfer from the tiniest to larger zooplankton and from mussels to shore crabs. There is parallel risk for harmful chemicals associated with microplastics to increasingly concentrate in animal tissues, adding threat to humans and other life forms dining at the top of the chain.
Scientist are also discovering direct ingestion of microplastics by fish which humans eat and that toxic chemicals from the plastics transfer to fish flesh.
Beginning with the pioneering measurements of plastic debris in the North Pacific Gyre by the Long Beach-based Algalita Marine Research Foundation, the buildup of plastic pollution in all five of the world's oceanic gyres is now well-established. Together with the recent discovery of microplastic accumulation in the U.S. Great Lakes and some rivers, this has spurred tangible momentum among some U.S. politicians toward elimination of microbeads in personal care products.
For example, the Great Lake states of Ohio, Michigan, Illinois and New York all considered legislative bans last year, though Illinois emerged as the only state to enact one, effective late 2017. The 2013 study spearheaded by Santa Monica's 5 Gyres Institute reported that much of the microplastic debris in the Great Lakes strongly resembles microbeads in cosmetics. Lake Ontario was most polluted, approximately 1.1 million microplastic fragments per square kilometer.
Then just this April, New Jersey became the second state to enact a ban, citing that manufacturers were already largely on board, given pledges to phase out microbeads by several corporations including Colgate-Palmolive, Johnson & Johnson, L'Oréal, Proctor & Gamble and Unilever. Besides, alternative abrasives can be made from many natural materials, like beeswax, walnut shells, apricot pits, sand or salt crystals.
Meanwhile, California reintroduced a proposed statewide ban in February 2015 (AB 888, Bloom) after a similar bill failed passage last year by a single vote. California's ban would take effect Jan. 2020. New York's Attorney General has also signaled intention to shoot for a ban again this year, citing that microbeads were found in three-quarters of samples of treated effluent from New York waste treatment plants. Additional states currently considering bans include Connecticut, Hawaii, Oregon and Washington.
There's even a possible national ban in the works. Two U.S. Representatives, Fred Upton of Michigan and Frank Pallone of New Jersey, have re-introduced a bill which stalled last year that would ban the sale of products with microbeads starting Jan. 2018. Because Upton is the Republican chair of the House Energy and Commerce Committee and Pallone is the ranking committee Democrat, there is greater hope for successful passage this time around.
Things are heating up outside the United States too. The international Beat the Micro Bead campaign touts 66 participating NGOs in 32 countries and offers a free download app allowing shoppers across the globe to scan barcodes to identify which products contain plastic microbeads. The campaign's website also posts lists of products by country that contain microbeads.
Moreover, Germany plans to promote an international effort to reduce waste from plastics, including microbeads, at the June economic summit of the Group of Seven (G-7) nations.
Appearing in the February issue of Science magazine, the findings of the first large-scale study to estimate how much plastic is actually going into the oceans are nothing short of shocking. Using data from 192 coastal countries, the researchers calculated that, just in the year 2010, between 4.8 and 12.7 million metric tons (roughly 10.5 to 28 billion pounds) entered the oceans. If nothing is done to stem the inflow of plastics, those numbers could increase ten-fold by 2025.
Given these sobering figures, world-wide elimination of microbeads in personal care products, an entirely avoidable source of plastic pollution, can't happen soon enough.
Older Article: News From the Shores of Ocean Beach and Point Loma
Newer Article: Grand Canyon in the Crosshairs? Risky Mega-Development Moves Forward
OB History: The In-Between - a Place Where Young People Could Hang Out
San Diego During World War II – Life on the Home Front - OB Historical Society Presents - Thurs., Jan.20

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: How to delete all history of specific website in google chrome In google chrome in history section, I want to delete all the histories related to a specific website for example: facebook.com, I can search facebook.com and then select all checkboxes and delete but its a time-consuming work.
Is there any easy way to clear the history of specific websites?
even by writing code or script?

A: open the history manager, search for facebook.com... do not click all the checkboxes individually. Click the first box, scroll to the bottom of the page and hold shift while clicking the last box, it will select all of them at once.
protip: if you want to visit a website without leaving a history entry, go into incognito mode (control-shift-p).
or, Control-A keyboard shortcut will select all of the checkboxes as well! https://techdows.com/2018/02/chrome-history-page-ctrl-a-now-selects-all-history-items.html#:~:text=Chrome%20history%20Page%3A%20Ctrl%2BA%20now%20selects%20all%20items&text=Now%20the%20addition%20of%20Ctrl,or%20unselect%20multiple%20history%20items.&text=The%20thing%20is%2C%20only%20150,page%20has%20more%20history%20items.

A: You can use some scripting in the console to click checkboxes for entries with hrefs containing a substring.
This answer uses this other SO answer on a querySelectorAll that works for things inside open shadow DOMs:
function $$$(selector, rootNode=document.body) {
    const arr = []

    const traverser = node => {
        // 1. decline all nodes that are not elements
        if(node.nodeType !== Node.ELEMENT_NODE) {
            return
        }

        // 2. add the node to the array, if it matches the selector
        if(node.matches(selector)) {
            arr.push(node)
        }

        // 3. loop through the children
        const children = node.children
        if (children.length) {
            for(const child of children) {
                traverser(child)
            }
        }

        // 4. check for shadow DOM, and loop through it's children
        const shadowRoot = node.shadowRoot
        if (shadowRoot) {
            const shadowChildren = shadowRoot.children
            for(const shadowChild of shadowChildren) {
                traverser(shadowChild)
            }
        }
    }

    traverser(rootNode)

    return arr
}

arr = $$$('[href*="example.com"]');
// this code will need to be updated if the source code for the chrome history browser changes.
arr.map(e => e.closest("#item-info")
  .previousElementSibling
  .previousElementSibling
).forEach(e=>e.click());

This will click all the matching entries on the current page, and then you can just click the button to delete the checked entries.

redpajama_set_name: RedPajamaStackExchange


Whoa! This is pretty deep advice for a soon-to-be 2nd grader.
It might just be what my soon-to-be college students need to hear as well.
True, none of these tidbits are new to the realm of inspiration but they may be new in this order. If nothing else, I now had some jumping off points for my "ultimate guide." My job now is to figure out how to present these epiphanies in a not-so-typical way.
If you had the chance to speak to incoming college students, what advice would you give?
What do you think are "ultimate" ideas for advice to share?
I am thinking of starting the presentation by zip lining from the back of the auditorium or being shot out of a cannon or something powerful that lives up to the "ultimate" theme.
Anyway…. As you take on the current and upcoming tasks in your life, be sure to do your best and forget the rest, ask questions, and don't be afraid to fail. Share what you know with others and be generous with the knowledge gained from your own triumphs and trip-ups.
Whatever you face, be sure to put intentergy into your efforts and you will come out anything but typical.
P.S. I really would appreciate any advice you think would be helpful to our future students.


text:
CR Products
Existing Products
urbanleafpkg
Cannabis labs eager to aid with COVID-19 testing with 10,000 backlog in Ontario
Health Canada is working to identify lab capacity to assist with supporting COVID-19 testing
Talia Ricci CBC News·Posted: Mar 27, 2020 1:18 PM ET
High North is a cannabis analytical facility located just outside of Toronto. Its CEO, John Slaughter, says the 16,000-square-foot space can easily be re-tooled to assist with COVID-19 testing.(Submitted by High North)
When John Slaughter finished construction on his 16,000-square-foot cannabis analytical testing facility last year, he never could have predicted it would potentially serve a totally new purpose in the face of a global pandemic.
"It's a gorgeous facility that can scale up and do anything needed in the laboratory industry," said Slaughter, the CEO of High North.
Usually, the company's laboratories test cannabis for qualities like potency and pesticides. Now, as the provincial and federal governments call on businesses and manufacturers to help with the COVID-19 pandemic, Slaughter has been advocating for the new cannabis sector to be considered.
Slaughter says his facilities are brand new, tests are processed digitally and standards are high.
"The level that [Health Canada] sets the standard to is if an immunocompromised cancer patient is going to use this product. That's the level of cleanliness that needs to happen," he said.
When CBC Toronto spoke with Slaughter Thursday, he said he was having a tough time reaching the right people to let the government know his space was available.
Health Canada didn't respond to CBC Toronto's specific questions about how companies can offer their services. Then on Thursday evening, all cannabis licence holders — including Slaughter — received an email from Health Canada saying it was "working to identify lab capacity that might be available across the country in various sectors, including at licensed cannabis production sites, to assist with supporting COVID-19 testing."
The email goes on to say that companies with lab facilities interested in assisting can notify Health Canada by email.
Ontario has a backlog on testing. Over 10,000 Ontarians who have been tested for COVID-19 are waiting for their results.
Slaughter says his labs could potentially process up to 1,200 tests per day with an investment in some additional equipment.
"These are world class facilities that need one tweak, they're looking for COVID."
Cannabis companies step up
George Smitherman, president and CEO of the Cannabis Council of Canada says many marijuana producers have already been responding at a local level.
"This is a start up sector, these are all new businesses, not that many are particularly profitable," he said.
"So it's been heartwarming to see even with some of the struggles these companies are facing, they were able to put the need of community and public health right out there."
Cannabis producer Aurora has donated N95 masks to Alberta Health Services, New Brunswick's Organigram donated ethanol for the production of hand santizer, while both Quebec's HEXO and Ontario's CANOPY donated personal protective equipment to their local emergency services.
As a former minister of health and long-term care, Smitherman says he's happy to help cannabis companies navigate reaching the right people within the government, but he also recommends reaching out directly to nearby hospitals.
"If you have resources locally, reach out to people in the healthcare sector," he said.
Smitherman says he's going to populate a list of capabilities within the broader cannabis space and have it ready to present to officials.
Meanwhile, Ontario has launched a website calling on businesses and workers to submit how they can help the province meet the challenges COVID-19 presents.
The email cannabis licence holders received from Health Canada is welcome news for Slaughter — who says his team has already been preparing to switch gears over the last two weeks, and they're eager to move to the next step.
"We've got a global pandemic, let's deal with this, let's help," he said.
Cannabis retailers in B.C. seek green light to deliver pot and compete with illegal dealers
Saskatoon marijuana stores concerned about new competitors flooding market
Health Canada reinstates some CannTrust cannabis licenses
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The ladies hosted SCC #2 Rio Hondo Friday, defeating the Roadrunners 2-1 to finish off the conference season with an undefeated record. Angel Rodriguez and Ivy Vollaire each scored for the Panthers. Esmeralda Garcia earned four saves. The ladies will begin CCCAA playoff action next week.


seep through the veins of my body.
Words that greet my being alive.
as it shelters the new grass of the dark field.
I hear in the sky, in the wind.
Today I bath in its ceremony, its sacred waters.
I see on the breast of blue.


One of the great things about CTN is the variety of things that happen over the course of the weekend. There are Live Demonstrations, Networking mixers, Master Workshops, Panel Discussions, Business Seminars, Recruiting/ Portfolio Reviews, and Professional Exhibits as well as One on One personal consultations with industry professionals. The attendees vary from undergrads to professionals and not limited to those interested or already working within the animation community.
This was my second time attending CTN. I was there in 2012. One of the first things I noticed was that as I imagined, it has grown. Exhibitors were not only in the main convention area but in an outdoor tent as well. They even had another tent outside to for panel discussions.
On Friday evening I attended a panel called "The Visionaries: Directors". It was moderated by Tony Bancroft. The panelists were Rob Minkoft, Will Finn and Shane Acker. For the most part they shared their experiences of being a director and how they ended up directing feature animations. Minkoft shared that he always noticed how apparent a director's influence was in Warner Bros. cartoons compared to Disney cartoons where the animators were more prominent. Bancroft shared that he got started directing by simply telling people that's what he wanted to do and was eventually given the opportunity based on expressing that desire.
Saturday was a pretty hectic day for me. I attended a motivational seminar "Accomplish your Creative Goals and Projects Now. Don't Wait for the Perfect Moment" presented by Gary Montalbano. The title says it all. The most valuable thing I walked away with was "trust your unique talents, trust your personal growth." Then I attended a panel called "The Women of Pixar: Animation and Story" where Valeria LaPointe, Gini Santos, Becki Tower and Kristen Lester each shared their trials and tribulations of being in predominately male spaces. The panel was moderated by Angelique Reisch. I really enjoyed this panel, the ladies were hysterically funny. I do wish that it was "Women in Animation" and women who worked at other companies such as Dreamworks, Blue Sky and Sony Pictures Animation were on the panel as well. I feel that hearing experiences and similarities from women who worked at different companies would have been worth hearing.
Then I attended "A Conversation with Legendary Animator Andreas Deja" That was simply amazing! Hearing seeing him and hearing his journey in person and not reading it from books, posts and podcasts was a great experience. To close the night I and many others saw Song of the Sea. Director Tomm Moore was there to introduce the film and stayed afterwards for a Q&A. I stood up for the whole thing and it was worth it! Seeing it a second time I got to catch things I didn't or couldn't the first time I watched it.
On Sunday, the last day of the convention I attended "A Process of Planning for Animation" which was a Master Workshop by Jason Ryan. This was great too because I have been following him for the last two years and I am currently reacquainting myself animation using his tutorials. Seeing him demonstrate his process, sharing advice and answering questions was much appreciated. The last event for me was probably the most helpful to my career, it was "Walt Disney Animation studios – Production Management: Making it Happen!" The Panelists were Heather Blodget, Nathan Curtis, Mike Haung and Leah Latham. This panel meant a lot to me because I have made the decision since having interned with NYICFF for almost year to switch my career track to Production Management. It was extremely reassuring for me to hear testimonies such as Leah's that was so similar to me. She went to school for animation, changed majors to storyboarding, graduated and realized her talents for more managerial things and pursued that.
Like I said in the beginning of this post there were so many artists, studios, software companies and publishing companies at the expo. I collected so many business cards and bought my share of artwork and pins. Besides being an attendee I was also helping out at The Book of Mojo table with the Director and creator Everett Downing.
I also got a chance to meet the creators of the Dam Keeper. It took me all weekend to get their picture since they had about 2 presentations and were doing portfolio reviews at their table.
Robert Kondo & Dice Dice Tsutusmi - Creators of "The Dam Keeper"
As expected I had a great time at CTNx. I met so many people, learned a lot, received great advice and more! Granted there are things the event can improve on overall. One thing I particularly would like to see is more of the artists, panelists, speakers, moderators reflecting the diversity of the attendees. It was beautiful seeing the variety of people that came out to the event and I'm sure many of us would like to look on those stages and see people that looked like us up there. We know they exist. Thanks for the memories CTNx!!


OCT. 24, 2018: In Washington, DC, mainly Wards 7 and 8, violence has increased tremendously. Many lives, from teenagers to elders, have been taken over ignorant and just dumb stuff.
Many of the killings in DC have either been shootings or stabbings. A lot of victims were teenagers leaving school maybe thinking about what their mothers were going to make for dinner. Other killings happened because of "hood beefs" or "school beefs". Nowadays, some students and parents are trying to figure out if they will be able to see their high school graduation.
In my opinion, our government, especially Mayor Bowser, continues to worry about the wrong things. When people confront her about violence in the community, she becomes speechless or says, "Next question". I don't believe she really needs to be our mayor because in my mind she doesn't even seem to want to solve the problems in the city that she's the mayor of. It seems like Mayor Bowser worries more about school attendance even though that is really important. She doesn't realize if people continue to die from senseless violence at this rate we may not even be able to have any attendance to keep track of.
Nowadays, many teens are killing other teens. I really wonder, how teenagers who are supposed to be underage obtain guns. I also wonder, why the Metro Police Department that is supposed to protect and serve the community, has not been able to stop the violence. In my experience, they show up to help stop the violence, just to make it seem as though they truly care. They are always posted up on Martin Luther King Jr. Ave—one of the roughest and violent streets in the entire city. But to me it looks like they are just sitting around and conversing with other police officers while violence is happening. Are they really here to protect and serve the communities or are they here to protect themselves from losing their jobs? I question why police response time is so long when the officers are just sitting around the corner.
Even though people are used to the violence in the community, there are many people who actually want to make a change, such as myself. How can we figure out ways to stop the violence in the community we live in. And, where do we start, because it feels like we never began?
Sean Beach is a 10th-grade scholar at Friendship Tech Prep Academy.


Q. Do you sell your email addresses or any other data in your database?
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A. We are updating all of our data on a daily basis. At a minimum each entry in our database is verified every 6 months.


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Business Wire: Medical
PRESS RELEASE: Paid content from Business Wire
Quad-C Agrees to Sell its Stake in Compassion-First to JAB
CHARLOTTESVILLE, Va. & LUXEMBOURG--(BUSINESS WIRE)--Feb 25, 2019--Quad-C Management, Inc. ("Quad-C"), a leading middle market private equity fund, and JAB today announced that they have signed a definitive agreement in which Quad-C will sell its stake in Compassion-First Pet Hospitals ("Compassion-First"), a family of well-known and respected specialty, emergency and general practice veterinary hospitals across the United States, to JAB, based on a total enterprise valuation of $1.215 billion. The purchase price takes into consideration the value of certain post-closing tax benefits. Veterinary service providers who are currently investors in the company will maintain a significant stake going forward, and Compassion-First's management team, including the Founder and CEO John Payne, will also continue to be significant investors and lead the company in the next phase of its development.
Compassion-First operates a network of 41 hospitals and treatment facilities across 13 states, primarily in urban and suburban areas. Founded in 2014, Compassion-First provides specialty, emergency and general veterinary care supported by seamless multidisciplinary collaboration among its veterinarians. Through its partnership model of delivering care, Compassion-First is committed to redefining how veterinary practices interact and connect with one another.
"It has been a pleasure to work with John Payne and the Compassion-First team to create a differentiated platform in veterinary medicine," said Tim Billings, Partner at Quad-C. "We started with a small group of hospitals in the Mid-Atlantic region five years ago and have assembled an amazing group of hospitals across the country. Quad-C is proud to have been partners with all of the exceptional veterinarians and employees who have joined the Compassion-First family and we wish the team continued success."
"I would like to thank Quad-C for its outstanding support and guidance during our foundational years at Compassion-First and setting us up for future success," said John Payne, President, CEO and Founder of Compassion-First Pet Hospitals. "As we look to the next chapter in our company's evolution, we can think of no better partner and shareholder than JAB, which brings a very long-term time horizon to its investments. Their support will allow Compassion-First to continue investing in our doctors, our technology and our practice to produce the highest-quality care and supply the tools, training, collaboration and leadership to make that care accessible in a growing number of communities."
"We are pleased to invest behind John and the management team as Compassion-First continues to deliver industry-leading organic growth and execute on its long-term strategy," said David Bell, Partner at JAB. "The dedication to being the best place for veterinarians to work, the absolute commitment to putting patients first and the continual focus on innovation to improve the lives of both pets and their families are values very much in line with the those at JAB, and we look forward to partnering with John and his team to further Compassion-First's success."
JAB will be investing equity capital from JAB Consumer Fund, an investment fund backed by a group of like-minded, long-term oriented investors, as well as directly from JAB Holding Company.
Jefferies LLC serves as exclusive financial advisor to Compassion-First through its Global Retail Healthcare franchise and Gibson, Dunn & Crutcher, LLP is acting as legal counsel to Compassion-First. Skadden, Arps, Slate, Meagher & Flom LLP is acting as legal counsel for JAB.
About Compassion-First Pet Hospitals
Compassion-First Pet Hospitals is a family of well-known and respected specialty, emergency and general practice veterinary hospitals across the United States. Founded in 2014 by John Payne, Compassion-First Pet Hospitals is comprised of hospitals working together through collaboration to advance veterinary medicine and increase access to multidisciplinary expertise. Compassion-First focuses on placing pet owners and their pets at the center of care. For a list of Compassion-First Pet Hospitals, visit http://www.compassionfirstpets.com.
About JAB Holding Company
JAB Holding Company and JAB Consumer Fund invest in companies with premium brands, attractive growth and strong cash flow dynamics in the consumer category.
Together, JAB Holding Company and JAB Consumer Fund have controlling stakes in Keurig Dr Pepper, a challenger and leader in the North American beverage market, Jacobs Douwe Egberts (JDE), the largest pure-play FMCG coffee company in the world, Panera Bread, a leading bakery-cafe company, Pret A Manger, a leading company in the ready-to-eat food market, Peet's Coffee & Tea, a premier specialty coffee and tea company, Caribou Coffee Company, a specialty retailer of high-quality premium coffee products, Einstein Noah Restaurant Group, Inc., the leader in the North-American bagel category, Krispy Kreme Doughnuts, a global leader in doughnuts and other premium-quality sweet treats, and in Espresso House, the largest branded coffee shop chain in Scandinavia.
JAB Holding Company is also the largest shareholder in Coty Inc., a global leader in beauty, and owns a controlling stake in luxury goods company Bally as well as a minority stake in Reckitt Benckiser PLC, a global leader in health, hygiene and home products. For more information, please visit the company's website at: http://www.jabholco.com.
About Quad-C
Founded in 1989 and headquartered in Charlottesville, Virginia, Quad-C is a middle market private equity firm focused on investing in well-established business services, consumer, general industrial, healthcare, specialty distribution and transportation / logistics companies. In its nearly three-decade history, Quad-C has invested over $3 billion of capital in over 65 companies. The Quad-C team is committed to partnering with entrepreneurs and management teams to accelerate growth and create long-term value. www.quadcmanagement.com
View source version on businesswire.com:https://www.businesswire.com/news/home/20190225005452/en/
CONTACT: For Compassion-First Pet Hospitals:
Lauren Carroll
lauren.carroll@compassionfirstpets.com
For JAB:
Abernathy MacGregor
Tom Johnson/Pat Tucker
tbj@abmac.com/pct@abmac.com
For Quad-C:
Jill Whiskeyman
Simpatico Studios, LLC
jill@simpaticostudios.com
KEYWORD: UNITED STATES LUXEMBOURG EUROPE NORTH AMERICA VIRGINIA
INDUSTRY KEYWORD: HEALTH PROFESSIONAL SERVICES FINANCE VETERINARY
SOURCE: JAB Holding Company
Copyright Business Wire 2019.
PUB: 02/25/2019 07:00 AM/DISC: 02/25/2019 07:01 AM
http://www.businesswire.com/news/home/20190225005452/en


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CalPERS 2016 Proxy Season Results in Significant Accomplishments
Contact: Joe DeAnda, Information Officer
Progress made on proxy access, climate risk reporting, and board diversity
SACRAMENTO, CA - The California Public Employees' Retirement System (CalPERS) made significant progress towards corporate governance reforms in the area of proxy access, climate risk reporting, and corporate board diversity during the 2016 proxy season through various shareowner campaigns. CalPERS invests in more than 10,000 public companies worldwide, and uses its proxy voting rights at those companies to effect changes in line with its Global Governance Principles (PDF) and Investment Beliefs.
CalPERS' proxy access proposal at Old Republic International Corporation passed overwhelmingly with 74 percent shareowner support. Proxy access helps to ensure that corporate boards are independent, competent, diverse, and accountable to shareowners.
The System also co-filed climate risk reporting proposals at Anglo American, Glencore Plc, and Rio Tinto Plc. All three proposals received support from the company's management and passed with more than 95 percent shareowner support.
"We believe shareowner engagement is a critical part of good ownership," said Ted Eliopoulos, chief investment officer for CalPERS. "We are committed to consensus building with companies and other owners so policies are implemented that protect and grow our investment."
In addition to CalPERS-led proposals, 18 proxy solicitation campaigns were run in partnership with the New York City Comptroller's Office regarding proxy access. In total, 13 proposals passed with more than 50 percent shareowner support, including a landmark win at Exxon Mobil.
As a continuation of the CERES-led Carbon Asset Risk Initiative and the Paris Agreement, CalPERS also committed to publicly support climate risk proposals at 11 U.S. companies in 2016. Proposals at two of the companies, ConocoPhillips and Marathon Oil, were withdrawn prior to a proxy vote because the companies agreed to implementation during engagement discussions.
Although the other nine proposals did not pass, the average level of shareowner support was 35 percent, a significant increase from 21 percent in 2015.
"This year was unprecedented for shareowners who spoke clearly on the issues that matter for long-term sustainable returns: board accountability, climate risk, and diversity," said Anne Simpson, CalPERS investment director of Global Governance. "There is more work to be done, but through our partnerships with organizations and owners such as Ceres, CCLA Investment Management, and the New York City Comptroller's Office, we are seeing real results on issues that matter for long-term owners."


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The Emerald Triangle's Brutal Pivot From Black Market to Legal
Growers no longer have to hide their crop from cops in helicopters, which was the one real advantage the Emerald Triangle had for growing weed.
By Patrick Wagner April 10, 2019
For roughly 20 years the getting was good in Northern California. From the legalization of medical marijuana in 1996 to beginning the transition into adult-use sales in 2016, cannabis growers in the remote, northern forestland enjoyed an idyllic life, earning a small share of fame and fortune at the constant risk of being raided by the DEA.
Bloomberg Creative Photos | Getty Images
Those days are over.
The surrounding communities of Humboldt, Mendocino and Trinity counties, long abandoned by the logging industry, were in many ways saved by medical marijuana, but those legacy growers now face new challenges. Legalization may have brought legitimacy to the northern guerilla growers, but the price of operating in the adult-use market has increased dramatically, forcing many longtime growers into early retirement or back into the black market.
Those who remained in the game had to get a license and struggle against deep-pocketed competition.
"It's sad to see some of the best growers I know decide to retire and bow out to what's happening," says Ryan Zuccaro, the founder and co-owner of Fresh Off the Hill in Humboldt County. "I'm all about change, but some people can't handle that change."
Recognition for the world-famous growing region remains high, but many advantages of the Emerald Triangle have become hindrances for commercial commerce. Meanwhile, with the introduction of cannabis to the agricultural hub of central California, Emerald Triangle growers are turning to new business models, opportunities for expansion and cost-saving techniques to stay out of its monolithic shadow.
Related: 7 Reasons Legal Cannabis Is a Recession-Proof Industry
Cost Competitive
The Emerald Triangle's small, family farms can't compete in terms of scale with the giant commercial producers in the Salinas Valley and other agricultural hubs. But in terms of overhead and focus, farms such as Shepherd's Meadow in Mendocino County have a distinct advantage.
"At Shepherd's Meadow, it's really only me and my wife," co-owner and head cultivator Brandon Waluk says. "I get a little bit of help from friends, but basically, it's just me."
Waluk aims to preserve his serene family life by focusing on flower quality and economic and environmental sustainability. The majority of his farm's operating costs are offset by solar panels, and while the farm only has approximately 7,000 square feet in production, every plant at every stage gets personal care from Waluk.
"It's from a desire to grow the best herb possible by any means," Waluk says. "We're conscientious of everything."
After growing cannabis for nearly 20 years, Waluk is always tinkering with his formulas to produce better flower. The farm utilizes indoor, outdoor and greenhouse production techniques as well as home-brewed compost teas, integrated pest management, Korean natural farming practices, reusable soil and fine-tuned nutrient regimens.
"I love being able to bang something out and try something new. I love that," Waluk says. "But what I like about outdoor is that I get all the time to build the soil and do all the cool stuff you can do with living dirt. It comes back to sustainability. When you turn off the light as you leave the room, it's not just saving you money, it's also that oil isn't burning somewhere for that power. It's common sense."
Growers like Waluk also have an advantage over their southern competition with the branding and legacy of the Emerald Triangle cannabis community. But maintaining a premium price for niche, hand-grown and hand-trimmed cannabis, isn't sold on just a zip code. Waluk and his wife are constantly updating their social media feeds, giving consumers and vendors an inside look at the farm's beautiful scenery and organic cultivation practices.
Related: How This Food-Delivery Entrepreneur Pivoted to Cannabis-Delivery
At Humboldt Highline, co-owner Josh Monschke doesn't mince words when it comes to the company's new focus on clone sales over flower.
"For us, it was that the price of flower has gone to s--t," he says. "The nursery was a revenue generator."
To be fair, the colorful price Monschke is referring to is $1,100 a pound; enough to validate the farms' hilltop property, but not reliable enough to continue building the company.
"The farms, for me, they're really great and they're up in the hills and really pretty," Monschke says. "But logistically, it's challenging."
Humboldt Highline straddles the line between farm and nursery. For Monschke and a small group of other farms in the area, clone sales have been mostly a side business. Nearly every farm focuses on flower and little else, he says. But as competition has driven the price of flower down, the value of clones remained roughly the same. Although Humboldt Highline's clone operation is roughly one-third the size of its flower site, it has become the company's leading source of revenue.
Monschke says the clone nursery is not the romanticized Humboldt farm people tend to expect, which can be frustrating during a time when companies are actively seeking new partners.
"With investors, the clones aren't exciting to them," he says, "but you show them the numbers and they get more excited."
Humboldt Highline's asking price for a single clone is $8. The average order the company receives is between 1,000 and 1,500 cuttings. Clones take 14 to 18 days to be ready for sale, and the company staggers its production schedule so its next wave of inventory is always just days away. Humboldt Highline is in the process of tripling the size of its nursery from 7,000 square feet to 21,000.
"I thought there would be more people producing clones, but people seem to focus more on flower," Monschke says. "It pays better than flower, that's why I don't get it."
Related: 11 Facts Cannabis Entrepreneurs Should Know About the Black Market
While most Emerald Triangle growers are buckling down or transitioning to a specific niche, Ryan Zuccaro is gearing up to compete directly against commercial farms in central California. Zuccaro owns roughly 250 acres in Humboldt County, and the company he founded, Fresh Off the Hill, is adding another 363 acres and 23 greenhouses, as well as a distribution license he hopes will make his company a logistical hub for California.
"We were getting murdered on distribution," he says. "Everyone has got their own motives and it's not usually in my favor. When my weed gets white-labeled I know it goes straight down to San Diego and my brand recognition is not going to be there."
Like the majority of Emerald Triangle cultivators, Fresh Off the Hill benefits from its Humboldt location and its packed Instagram account of charming hillside plots overlooking Northern California. But that's mostly for branding. The real production happens further down the hill at its 363-acre plot where the land is flatter.
"We got test results that came in at 33 percent (total cannabinoids) yesterday. It was all full sun, all outdoor, seed starts," Zucarro says. "I am going to safely say that we're going to get our 2,000 pounds (of flower) and hopefully some more."
Despite Fresh Off the Hill more than doubling its size over the next year, Zuccaro says the focus remains on sustainability.
"It's been exploding right now," Zuccaro says. "But we're cutting our costs and putting our money into places that we see it come back to us. We're just trying to grow the best pot we can for as cheap as possible."
Fresh Off the Hill, Humboldt Highline and Shepherd's Meadow are just a handful of the farmers striving to continue the Emerald Triangle's legacy of world-famous cannabis. With the right management and business practices, Northern California's savvy cannabis businesses can remain high enough on their hillsides to keep dry during the oncoming flood of flower.
"Things change. Manufacturers here cannot make 600 percent over what they put in," Zuccaro says. "You have to be realistic and look at a good 5-10 percent margin and be okay with that."
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6-Year-Old Boy Struck By Car In Durant - KTEN.com - Texoma news, weather and sports
6-Year-Old Boy Struck By Car In Durant
Sunday, September 20, 2009 11:17 PM EDT
A six-year-old child is recovering Sunday night after being struck by a car, while playing in front of his house.
It happened around 5 o'clock Sunday at the corner of Dana Drive and Harmony Drive - on the west side of Durant. The child was taken to MCSO as a precaution, but it's believed he only suffered from minor bumps and bruises. Neighbors say the driver of the car was traveling too fast down the street.
"I'm upset to see one of our neighbors' kids get hit by a car because somebody can't obey the law," said Mike Molebash, a neighbor. "Pretty disappointing."
No word on if the driver was ticketed or if they will face any charges.
KTEN News


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[★VIDEOS] Mckay Kim is back with a new mashup featuring BIGBANG, 2NE1, SHINee, and Taeyang
Mckay Kim is back with another refreshing mashup after blowing fans away with a remix of Ed Sheeran, Bruno Mars, EXO, and more last week on Pikicast. Mckay starts off with a soulful rendition of Taeyang's summer hit "Eyes, Nose, Lips" before bringing in a different melody for SHINee's hot new track "View" and BIGBANG's first release in three years, "Loser."
He quickly picks up the speed as he blends the three tracks together with 2NE1's classic track "Lonely."
Fans have left positive responses on Twitter and YouTube calling the singer "Amazing! Perfection! Just…yes!????????????" encouraging the singer to release more covers as he works on music under Dorothy Company.


This price includes myself as the photographer and one of my assistants. Usually a session will last about two hours to three hours although I do not set a time limit. I also do not set a certain number limit to how many photos the couple will receive. What I mean by that is that while some companies might give price options for a certain number of photos, I do not limit the number of images that they will receive for the one flat fee.
Multiple locations and outfit changes are acceptable.


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Home » Biological Facts » Facts about Genes
Facts about Genes
What are Genes? Genes are hereditary functional units since they are composed of DNA. Genes are transmitted or inherited from parents to offspring. Chromosomes typically ...
Sourav Bio
Biological Facts
What are Genes?
40 Facts about Genes
Genes are hereditary functional units since they are composed of DNA. Genes are transmitted or inherited from parents to offspring. Chromosomes typically arrange and package genes, and genes are composed of either DNA or RNA, which regulate an organism's characteristics.
Genetics is the scientific study of genes, genome, heredity, cell cycle, and inheritance. It is a biological discipline. In 1905, William Bateson established the phrase genetics, and in 1909, a Danish botanist called Wilhelm Johannes developed the term GENE.
According to scientific views, the genes of all living things on Earth share certain similarities since we all emerged from a common ancestor.
Humans share a 95% genetic similarity with chimpanzees and are also genetically related to other animals, such as cats, cattle, etc.
Several further fascinating and surprising facts about genes are included in the following list.
Genes are the basic units of heredity, responsible for passing on traits from parent to offspring.
Genes are made up of DNA, a double-stranded molecule that carries the genetic code.
There are around 28,000 to 30,000 genes in each human cell and approximately 12,000 to 13,000 genes on each chromosome.
Genes are located on chromosomes, which are found in the nucleus of cells.
Chromosomes come in pairs, with one copy inherited from each parent.
Genes are made up of exons, which code for proteins, and introns, which do not.
Gene expression is the process by which a gene's code is used to make a protein.
Different forms of a gene, called alleles, can result in variations of a trait.
Genetic disorders are caused by mutations in genes.
Genes can also play a role in susceptibility to certain diseases.
Genetic testing is used to detect mutations or changes in genes.
The Human Genome Project was a large-scale international research effort to map and sequence the human genome.
Genes can be manipulated through genetic engineering, a technology used in agriculture, medicine, and research.
CRISPR-Cas9 is a powerful tool for editing genes.
Some organisms have more than 2 sets of chromosomes, called polyploidy.
Epigenetics is the study of changes in gene expression that do not involve changes to the underlying DNA sequence.
The study of genetics can help understand the underlying causes of diseases and potentially lead to new treatments.
Genetic research has also led to the development of personalized medicine.
Genetic variation is important for evolution.
Genes can affect behavior and mental health.
Genes are not deterministic, environmental factors also play a role in shaping traits.
The study of genetics also includes the study of genetic disorders and genetic diseases.
Many genetic disorders are caused by mutations in a single gene.
Some genetic disorders are inherited in a dominant or recessive pattern.
Some genetic disorders are caused by chromosomal abnormalities.
The study of genetics can also help understand the genetic basis of certain types of cancer.
The field of pharmacogenetics is concerned with how genetic variation affects an individual's response to drugs.
The study of genetics is also important for understanding the genetic diversity of populations.
Genetic research also has important implications for forensic science.
Genetic research is also used in the field of archaeogenetics to study human evolution.
Genes also play a role in plant growth and development.
Genetic engineering is being used to improve crop yields and develop drought-resistant plants.
Genes play a role in animal behavior and development.
Some genetic disorders are found only in certain breeds of animals.
Genetic testing can be used to identify and track specific genes in animal populations.
Some genetic disorders are caused by the deletion or duplication of a small piece of a chromosome.
Some genetic disorders are caused by mutations in the non-coding regions of a gene.
Some genetic disorders are caused by mutations in more than one gene.
Recent advancements in genetic research have led to the development of gene therapy, a treatment that aims to fix or replace faulty genes.
It is important to consider ethical and social implications of genetic research and its applications.
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Sourav Bio. (January 17, 2023).Facts about Genes. Retrieved from https://microbiologynote.com/facts-about-genes/
Sourav Bio. "Facts about Genes." Microbiology Note, Microbiologynote.com, January 17, 2023.
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We've all been there. We've all felt it—the realization that our goal hasn't been met and the painful disappointment that we experience at the same time. This negativity can be so damaging that it keeps us from trying again or believing that we can have a different outcome. Ugh! I like to categorize this experience and emotional pain as a success obstacle.
Success obstacle(s) can look different for all of us, but I believe if they aren't addressed in our journey of health and fitness, we will never be able to truly change our lifestyle in a positive manner. We all have ingrained patterns of behavior and thinking, and while I could spend blog post after blog post explaining the psychological theories to support this, I'll sum up my findings in a few useful tips that I recommend you start implementing as soon as possible if you are trying to improve your overall fitness.
The first step in identifying and overcoming a success obstacle is to know your enemy! What foods tempt you? What emotions trigger unhealthy behaviors? What so-called friends and environments initiate a downward spiral in your overall happiness and confidence? If you can start by listing these triggers, you'll be aware and prepared the next time you encounter them.
The second step in identifying and overcoming a success obstacle might take a bit more work. As a therapist, I often ask clients to make a list of the 10 people they see the most on a regular basis. Then I have them sort these 10 people into two lists: one, people who make them feel worse or hold them back, and two, people who lift up and encourage them to grow. I'm not saying that the regular people in your life will all fit into the first category. However, if you make a list of these 10 people and find that most or all fit in the first category, I suggest you "edit" your regular group and expand to find healthier people in your life. We all deserve love, support and a fan base that will encourage us to grow. And as you seek to improve your overall health, you can't have people in your life who are holding you back and not supporting you as you make these positive changes.
The third step in overcoming a success obstacle is to know what you are working with. Another activity I've had clients do is to make a list of their talents, innate characteristics, strengths and gifts they can give to others. Without writing these things down, it becomes messy spaghetti. It's accessible but mixed in with so many other thoughts and facts that it's hard to differentiate. I want you to know specifically what your strengths are and to have them accessible on a list so you can refer to them as you're on your fitness journey. There will be difficult days ahead, and if you don't know what you can do to overcome them, you're setting yourself up for a perfect success obstacle. This task might seem silly or oversimplified, but I promise you that having a visible and tangible list of strengths will be one of your biggest allies.
Once again, this is a short list to help you overcome the obstacles you will inevitably face along your fitness journey. Becoming a fitter, leaner, healthier person isn't about spending all of your time in the gym. We need to be able to look within and learn more about our patterns, weaknesses, and strengths so we can be prepared to make a radical change.
And finally, I leave you with this thought: Success obstacles are truly just minor hurdles that can be erased and/or greatly minimized with a bit of self-investment. Integrate some of these simple exercises we discussed, and you will start seeing positive changes even beyond your shrinking waistline!


In this code-heavy tutorial, learn how to build a logistic classification model in H2O using the prostate dataset to calculate AUC and GINI model metrics.
AUC (Area under curve) is an abbreviation for Area Under the Curve. It is used in classification analysis to determine which of the used models predicts the classes best. An example of its application is ROC curves. Here, the true positive rates are plotted against false positive rates. You can learn more about AUC in this Quora discussion.
AUC refers to area under ROC curve. ROC stands for Receiver Operating Characteristic. AUC is not always area under the curve of a ROC curve. In the situation where you have imbalanced classes, it is often more useful to report AUC for a precision-recall curve. You can learn more about AUC and ROC here.
For logistics classification problems, we use AUC metrics to check model performance. Higher is better; however, any value above 80% is considered good and over 90% means the model is behaving great.
We will also look for GINI metrics, which you can learn from Wiki. In this example, we will learn how AUC and GINI model metrics are calculated using True Positive Results (TPR) and False Positive Results (FPR) values from a given test dataset.
Let's build a logistic classification model in H2O using the prostate dataset.
Note: Above, you will see that our calculated ROC values are exactly the same as given by the model performance prediction for the test dataset.
Note: Above, you will see that our calculated GINI values are exactly same as given by the model performance prediction for the test dataset.


The Stormsword is a super-heavy tank of the Astra Militarum that is the result of an ad hoc field conversion of a wrecked Shadowsword tank. The Shadowsword's original Volcano Cannon and all of its internal components have been replaced with a massive Hellhammer Siege Cannon and internal storage for its huge shells.
The Stormsword has proven very reliable during urban combat, and is equipped to fight in close-quarters and against garrisoned infantry. The Stormsword fills the role of a close-combat super-heavy tank, whereas the Shadowsword fills the long-range role, the Stormblade fills the medium-range role, and the Baneblade fills the "all-around" role, capable of fighting equally well in close, medium, and long-range battles.
Like all of the variants of the Baneblade, the Stormsword came into being as the solution to a specific tactical need, in this case the Imperium's need for a super-heavy tank adapted to urban combat. The first Stormsword was not specifically designed as such by the Tech-priests of Mars. During one long and grinding battle for Coldarkh Hive on a forgotten urbanised world, the Enginseers salvaged a damaged Shadowsword, removed the no longer functional Volcano Cannon, and installed a Hellhammer Siege Cannon in its place. The resulting vehicle was named the "Stormsword" by its crew and both the design and name stuck when the Imperial commanders realised how effective a weapon the Enginseers had cobbled together. Since the resounding success of that battle, Stormswords continue to be crafted and put to use as urban siege engines.
Although the more dogmatic Tech-priests frown upon such field conversions, believing them to be an affront to the Machine Spirits and the Omnissiah, the more pragmatic amongst them judge the worth of a design on its results, and have accordingly standardised and started to produce Stormswords from scratch on their Forge Worlds.
On the battlefield, the Stormsword will only be fielded in those theatres where visibility and range drops to almost nothing, typically during urban or jungle campaigns. The colossal mass of the Stormsword allows it to plow through most obstacles unscathed, while its massive Hellhammer Siege Cannon can obliterate any fortification with a direct hit, and its secondary armament of twin-linked Heavy Bolters and Heavy Flamers allows it to flush out and gun down any opposing infantry with ease.
In the chaos of urban warfare, where range is often measured in metres and progress in the form of single buildings captured or destroyed, neither the relative short range of its armament, nor its poor speed and manoeuvrability hampers the Stormsword when delivering fiery devastation upon the enemies of Mankind. When assaulting a city, the Stormsword will spearhead the attack, blasting any fortified strongpoint to rubble, covering the advancing infantry with its secondary weaponry and motivating them with its very presence. Of all the close support tanks in the Imperium of Man's arsenal, the Stormsword is the most brutally effective.
For all its efficiency, the Stormsword does suffer from some drawbacks: its size and mass are as often a curse as a blessing, for there invariably will be instances where the Stormsword will be too large to fit and yet unable to plow through obstacles. As with all the Shadowsword variants, the Stormsword's fixed main gun requires that the tank be bodily aimed at the target, and the Stormsword's crew must be specially trained to identify and avoid pitfalls where their massive tank would bog down or shed a track with potentially catastrophic results.
The Hellhammer Siege Cannon has a very poor rate of fire, and is actually slightly too large for the Baneblade chassis, allowing a Stormsword to carry only 20 shots, 21 if the crew risks pre-loading the main gun. The Stormsword also lacks anti-armour armament, for only its main gun can destroy enemy armor, and thus the tank needs support from anti-tank infantry units when advancing. Lastly, the Stormsword is all but useless outside of urban combat, due to the short range and poor rate of fire of its main gun combined with the poor top speed and manoeuvrability of all the Baneblade variants.
The Stormsword represents an implementation of STC canon upon which many within the Cult Mechanicus diverge. The vehicle is more invariably the result of modifications made by Tech-priest Enginseers in the field. Most often, they were created by salvaging the hulls of otherwise heavily damaged super-heavy tanks, in particular a number of variants derived from the Baneblade, replacing a destroyed main weapon with a heavy siege gun.
The result was a super-heavy tank that was almost unparalleled in the urban assault role, its massive main gun able to bring down any building and scour defenders from even the heaviest cover. Because of its origins, few Stormswords were exactly the same. Certain Tech-priests claimed however that some perfectly functional Shadowswords and other super-heavies had been deliberately converted into Stormswords for use by the Solar Auxilia Cohorts in urban war operations. If true, this was a significant transgression of a number of rigid doctrines by which the Mechanicum operated and a potential cause of costly doctrinal schism. The Stormsword was also found in the armouries of some of the Space Marine Legions, in particularly the Iron Warriors Legion.
In the 41st Millennium, the Stormsword, a name coined by the Imperial Guard's ancient predecessors, the Imperial Army, is not an officially recognised STC design, and the more conservative elements within the Adeptus Mechanicus look down upon those regiments who deploy them. The Imperial Guard commanders on the ground have a much more pragmatic view of the situation since this pattern of super-heavy tank has more than proven its worth on multiple occasions. In the 41st Millennium, some Forge Worlds have even begun producing Stormswords in limited numbers rather than as conversions of damaged Shadowswords. The most common pattern of the Stormsword is the Arkurian Pattern.
The Stormsword uses the massive Hellhammer Siege Cannon as its main weapon. This massive ballistic artillery piece launches a 180-kilogram, rocket-propelled shell packed with enough explosives to bring down most buildings with a single hit. The Stormsword's gunners are trained to aim at the base of the building to ensure its collapse. Due to the size of its shells, the tank can only hold 20 and the reloading process is painfully slow.
The propulsion system for the shells gives the Hellhammer slightly longer range than the more common Demolisher Cannon. The Stormsword is used as a front-line main battle tank during urban battles. The Stormsword clears the way for infantry and other armoured vehicles and it can destroy most obstacles by simply running them over. The tank is also armed with sponson-mounted Heavy Bolters or Heavy Flamers with top sponson-mounted Lascannons, and can be armed with an additional set of sponson weapons. The tank can be outfitted with a pintle-mounted Heavy Stubber or Storm Bolter, a Hunter-Killer Missile Launcher, Improved Communication Systems, Searchlights, a mine sweeper, and Smoke Launchers.
A Stormsword excels at clearing enemy choke points. The shells fired by its Hellhammer Siege Cannon release a concentrated concussive wave upon detonating. Those not outright pulverised by the initial blast are torn apart by the very cover they thought would protect them. Metal barricades are reduced to clouds of shrapnel, and chunks of ferrocrete bunkers are sent hurtling through the air to crush those they once housed.
Throne of Ishrehael - Throne of Ishrehael was a Stormsword of the 6th Cadian Armoured Regiment. It fought against the Forces of Chaos during the 13th Black Crusade of Abaddon the Despoiler.
Refutation of Sin - The Refutation of Sin was a Stormsword belonging to the 18th Atraxian Super Heavy Tank Company. This Stormsword fought in both the Kalidar War and the Geratomran Reconquest.


Serine residues in proteins are the primary targets for PARP-dependent ADP-ribosylation signalling upon DNA damage.
Brittany J Belin et al.
An efficient response to DNA damage requires the assembly of actin filaments in the nucleus.
Genetic and cell biological study indicates that germ cells' connectivity serves as a mechanism to increase the sensitivity of germline to DNA damage, protecting the genome of gametes, in the Drosophila testis.
Development of a generally adaptable conformational capture assay for use in-trans identifies the specific direct interaction sites between the parvovirus minute virus of mice and the cellular genome during infection as sites of cellular DNA damage.
Stephanie J Papp et al.
The circadian clock proteins, cryptochrome 1 (Cry1) and 2 (Cry2), evolved from bacterial light-activated DNA repair enzymes to detect DNA damage and coordinate the gene expression response.
The dual function of an ancient prokaryotic enzyme, which is linked to specific metabolite signals, may have been the evolutionary driving force behind its dual localization in eukaryotes.
Caroline Townsend Stork et al.
The transcriptional response elicited by the hormone estrogen leads to DNA double-strand breaks by promoting R-loop formation in breast cancer cells.
Owen A Brady et al.
Disruption of TFEB and TFE3 results in diminished p53 signaling capacity and altered cell cycle regulation under genotoxic stress conditions.


text:
Indicators on Alien You Should Know
May 25, 2019, 6:27 am / mylesdyrke.bloguetechno.com
^ Incorporates vocals at first and during the fade-out. ^ Consists of vocal interjections at the conclusion of the second and 3rd verses. ^ Incorporates screams of "do the hustle!" at the end of each refrain. ^ Consists of vocal interjections of your title monitor at the end of Just about every chorus and "up, up into the sky" as an ending. ^ Includes vocals, which total 30 terms and so incorporates one of the most lyrics of any instrumental track to strike No 1. ^ Is made up of, all through its choruses, several nonsensical vocal interjections with the title. ^ Originally, ahead of the major piece commences, it functions the lyrics "Oh yeah, I used to know Quentin, he is a true, he is an actual jerk".
Commencing in 1954 the 356s engines commenced employing engine instances designed especially for the 356. The sleek bodywork was made by Erwin Komenda, who also had made the body in the Beetle. Porsche's signature layouts have, from the beginning, highlighted air-cooled rear-motor configurations (much like the Beetle), uncommon for other automobile suppliers, but generating cars that are incredibly well well balanced.
Each and every institution he appointed was for being instrumental to the creation of these three grand objects.
Animal Behavior. a stylized sample of actions performed by an animal, like a hen in courtship display, or an insect, like a honeybee in indicating a source of nectar.
The crew of the colony ship, sure for the distant planet, uncover an uncharted paradise with a risk outside of their imagination, and must try a harrowing escape.
R. Kelly has faced accusations of sexual abuse, when XXXTentacion was on demo for domestic abuse in the scenario that did not access a judgement just before his death that June.[280] This policy was revoked in June since the company deemed the original wording to get too "imprecise"; they said that "Throughout all genres, our purpose is not really to manage artists. Thus, we are going far from applying a policy close to artist perform".[281] Even so, artists including Gary Glitter and Lostprophets are still concealed from Spotify's radio stations and search results.[282]
Freddy has been affectionately taxed by his betrothed with getting been instrumental in its despatch, but he has delicately denied.
Instead, you'll truly feel restless and disgruntled. A blocked Coronary heart Chakra also can manifest bodily. Some Chakra experts Feel this type of misalignment could be associated with issues like large blood pressure level and reduced Porsche immune program functionality.
Thank you a lot of for watching this video by Just Instrumental New music channel. I hope you enjoy it and do not forget to Subscribe :)
The 2019 Porsche 718 Boxster's sublime driving dynamics, punchy turbocharged flat-four engines, common styling, and swiftly folding gentle major enable it to be a person heck of a sporting activities car or truck—one that we frequently increase to our yearly 10Best Cars and trucks listing.
Pietro Grossi was an Italian pioneer of Laptop or computer composition and tape tunes, who very first experimented with electronic procedures during the early sixties.
In August 2016, Spotify launched Launch Radar, a personalised playlist that enables consumers to remain up-to-date on new new music launched by artists they pay attention to probably the most.
Set your still left hand on the left knee plus your appropriate hand before the reduce portion of your respective breastbone.
The earth's very first computer to play tunes was CSIRAC, which was created and built by Trevor Pearcey and Maston Beard. Mathematician Geoff Hill programmed the CSIRAC to Participate in common musical melodies in the pretty early nineteen fifties. In 1951 it publicly performed the Colonel Bogey March, of which no regarded recordings exist, only the exact reconstruction.[66] Nevertheless, CSIRAC performed normal repertoire and wasn't utilised to extend musical wondering or composition follow.
Comments on "Indicators on Alien You Should Know"


Temporary information Hostel in temporary premises whilst 20-22 Quex Road, NW6 address is refurbished. Due to move back Autumn 2012.
Irish Centre Housing Limited, 1 Holmes Road, London, NW5 3AA Phone 020 7485 8889.


Children will explore the life of a cowboy and his horse through traditional songs, large motor movements, stories, and more.
Attached you will find the final lesson plan of the summer. I know I can't wait to mosey on down to the ranch this next week. Please, "Don't Fence (Your Excitement) In" (I could not resist!) and keep your energy up. Rashaan and I have been talking about how wonderful this summer has been and it has been because of you and your tireless energy and enthusiasm. Please don't let the dog days of summer get you.
We will also be hosting a Chuckwagon Lunch on Friday. Details will be coming soon to the classrooms.
Bugs and farm animals will be the focus of study during the ranch theme. Shovels, buckets and, jars will be given to the children to search, capture, and learn about bugs under and above the earth. Also, farm and ranch animal skins as well as the diagrams of their anatomy will be displayed. In addition, their diets will be discussed. Children will learn why these animals are important to humans.
Shooting Stars will provide items like boxes and chairs to create a ranch with covered wagons, horses and trains. We will use paper bags to make cow girl and boy/girl vests and we will add cow boy/girl boots and other clothing….etc.
The Comets will create a barn with all of the fix'ins (fixings). We will also create and decorate animal mask and cowboy hats. Lastly we will build small ranches using Lincoln logs.
Art and Construction(prepared by the Comets)The Comets will create a barn with all of the fix'ins (fixings). We will also create and decorate animal mask and cowboy hats. Lastly we will build small ranches using Lincoln logs.


text:
Q: Deserializing nested XML into arrays I've been trying to deserialize an xml document into a class.  I've done this before, but not with this much nesting.  I'm pretty much trying to replicate a simple directory tree.  The issue I'm running into is the file aspect.  the directory section works and i can get to the files, but deserializing the file names to my class isn't quite matching up.  My XMl doc is:
<?xml version="1.0" encoding="utf-8"?>
<Directories>
<Directory Path="Path1">
<Files>
  <File Type="None">File1</File>
  <File Type="None">File2</File>
  <File Type="EXE">File3</File>
</Files>
<Files>
  <File Type="DLL">File4</File>
  <File Type="None">File5</File>
  <File Type="EXE">File6</File>
</Files>
<Files>
  <File Type="DLL">File7</File>
  <File Type="None">File8</File>
  <File Type="EXE">File9</File>
</Files>
</Directory>
<Directory Path="Path2">
<Files>
  <File Type="DLL">File10</File>
  <File Type="None">File11</File>
  <File Type="EXE">File12</File>
</Files>
<Files>
  <File Type="DLL">File13</File>
  <File Type="None">File14</File>
  <File Type="EXE">File15</File>
</Files>
<Files>
  <File Type="DLL">File16</File>
  <File Type="None">File17</File>
  <File Type="EXE">File18</File>
</Files>
</Directory>
<Directory Path="Path3">
<Files>
  <File Type="DLL">File19</File>
  <File Type="None">File20</File>
  <File Type="EXE">File21</File>
</Files>
<Files>
  <File Type="DLL">File22</File>
  <File Type="None">File23</File>
  <File Type="EXE">File24</File>
</Files>
<Files>
  <File Type="DLL">File25</File>
  <File Type="None">File26</File>
  <File Type="EXE">File27</File>
</Files>
</Directory>
</Directories>

and here is my class:
[XmlRoot("Directories")]
public class Directories
{
    [XmlElement("Directory")]
    public Directory[] Directory { get; set; }
}

public class Directory
{
    [XmlAttribute("Path")]
    public string Path { get; set; }

    [XmlArray("Files")]
    [XmlArrayItem("File")]//this causes the object to structure properly, but doesn't populate the string file property in the class with or without the attribute decoration
    public XmlFileInfo[] Files { get; set; }
}

public class XmlFileInfo
{
    [XmlElement("File")]
    public string File { get; set; }

    [XmlAttribute("Type")]//this works fine if this class is referenced as an array
    public /*External Enum*/ FileTypes Type { get; set; }
}

the above class with decorations properly populates the Type enum but with not the File string.  the following class with the decorations populates the file string with the first file in the files tree and doesn't properly populate the Type enum
[XmlRoot("Directories")]
public class Directories
{
    [XmlElement("Directory")]
    public Directory[] Directory { get; set; }
}

public class Directory
{
    [XmlAttribute("Path")]
    public string Path { get; set; }

    [XmlElement("Files")]
    //[XmlArrayItem("File")]
    public XmlFileInfo[] Files { get; set; }
}

public class XmlFileInfo
{
    [XmlElement("File")]
    public string File { get; set; }

    [XmlAttribute("Type")]
    public SignatureChecker_Mtabs.Program.FileTypes Type { get; set; }
}

What am i missing?

A: I reworked my class.  My issue was with the attribute for my xmlFileInfo.  I designed the class improperly and because of the time constraint am unable to correct this.  So instead I'm removing the attributes and going with this class
[Serializable]
//[XmlRoot("Directories")]
public class Directories
{
    //[XmlElement("Directory")]
    public List<Directory> Directory { get; set; }
}

[Serializable]
public class Directory
{
    //[XmlAttribute()]
    public string Path { get; set; }

    //[XmlArray("Files")]
    //[XmlArrayItem("File")]
    public List<XmlFileInfo> Files { get; set; }
}

[Serializable]
public class XmlFileInfo
{
    //[XmlElement("File")]
    public string File { get; set; }

    //[XmlAttribute()]
    public MyobstruficatedEnum Type { get; set; }
}


text:
Home Fact-Check Fact Check: Will FIFA keep Pele's Feet in the Museum?
Fact Check: Will FIFA keep Pele's Feet in the Museum?
Claim : There is a claim circulating on social media that FIFA would keep Pele's feet in the Museum.
Full text: The post reads, "BREAKING: FIFA Will Keep Pele's Feet in the Museum. Pele's Family has given the permission."
FIFA is the international governing body of association football founded since 1904.
About Pele: Edson Arantes do Nascimento, known mononymously by his nickname Pelé, was a Brazilian professional footballer who played as a forward. Regarded as one of the greatest players of all time and labelled "the greatest" by FIFA, he was among the most successful and popular sports figures of the 20th century.
They called him 'The King', and his face is one of the most recognisable in world football. He was once named by FIFA as the greatest player of the 20th century. The legendary Brazilian passed away on 29 December 2022.
Pele's star was already in the ascendancy at the age of just 17, when he celebrated his first FIFA World Cup title with Brazil in Sweden on 29 June 1958. He still holds the record as the youngest world champion of all time.
Verification: After a keyword search of the terms turned up no related result from any credible news platform. Similarly, there was no such announcement on the FIFA official website. Infact, a page with an outpouring of tributes for the legendary footballer on the website had no such announcement.
Further verification on FIFA's official social media handles especially Twitter and Instagram contained no such information.
However, some YouTube channels and Twitter handle have been confirmed to be speculating and spreading the rumors.
Conclusion: There was no official announcement by the Federation of International Football Association (FIFA) that Pele's feet will be kept in the Museum with the consent of his family.
PRNigeria therefore concludes that the cliam is FALSE.
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To get ahead of competitors.
To Drive your Brand Awareness.
Ensure You Retain Key Employees.
The top reasons survey respondents gave for leaving their jobs were, career development (22%), work-life balance (12%), managers' behavior (11%), compensation, and benefits (9%) and well-being (9%).
According to Linkedin research shows strong evidence that employees respond best when they are recognised for things they are good at and for times where they've had to stretch. It is these areas that make employees want to grow and achieve within your company.
How can You Improve Your HR Strategy to Ensure Employee Engagement?
Employee benefits are an essential aspect of any HR strategy; feeling valued is a key motivator for employees to be engaged. Both Flexible and Voluntary Employee Benefits show that as an employer you care about your employees, and also their families.
Not only do benefits mean that your employees are productive and engaged, but also that they remain at your company. Following the points in this article will help you not only engage your employees, but also retain them.
This quote demonstrates it is not just financial benefits that you should consider for your company. It is the rewards that mean something to your employees that will improve employee engagement, productivity, and happiness.We have created an article full of no cost benefit ideas you can offer your employees.
All companies are after one thing, and that is success. Your employees are also striving to achieve and they will want to know that they are helping your company to succeed.
Goal setting shows organisation, gives a clear path for employees to follow, and means that company targets can be met.
Specific-Ambiguous goals won't help you take your company further. Your goals need to be specific, so that they can be easily tracked to ensure that company targets can be met.
Measurable-Make sure that your employees can track how they are doing; this could be through meetings, or through tracking conversions.
Attainable-The goals you set need to be realistic and achievable by an individual at your company, so make sure that they are set for the employees standard.
Relevant-You need to look at the overall company strategy and set the most relevant goals to help you achieve this. Time Bound-Your employees should know when goals need to be met so they can prepare properly, and ensure everything is done to achieve them.
Value is a fundamental element of employee engagement, and a necessary aspect of company culture. Essential to this is positive communication; this means that an employee knows exactly what is expected of them and when they succeed, they are positively reinforced with complements. Any issues should be discussed with clear communication to understand what went wrong and how this could be improved next time. This needs to be constructive, and built on increasing confidence within the job role. The more confident an employee feels they better they will perform.
Your office space needs to represent your brand values, instilling creativity and inspiration into your employees. If your space is representative of your brand, then your employees are more likely to feel connected to your company's mission. If you ever have meetings within your office this will also inspire those you work with to become advocates of your brand.
Implementing these four key tips for a winning HR strategy, is likely to improve your employee engagement and boost your companies productivity. If you are considering offering benefits as part of your strategy, call a member of our team on 0808 281 1545 to discuss how offering a Will as part of your benefits package can enhance your companies HR strategy.


text:
Salem – Salem II
Overall Score: 9/10
songs: 9/10
lyrics: 8/10
replay value: 9/10
Pros: another fine collection of pristine pop punk
Salem's sudden emergence at the latter half of 2020 was one of the bright spots in an otherwise dismal year. Their debut self title e.p strode in like a candy coloured blast of fresh air. Another big bonus came in the form of them being able to play socially distanced gigs, giving fans the chance to hear the e.p live in full.
During those gigs fans were treated to 5 other brand new songs, and if you are anything like me you have been trying to get them out of your head for the last 8 months. Fans pondered how long it would be before they would have to wait to hear the full recorded versions of the new songs, thankully their prayers have been answered and Salem are back with a second self titled e.p Salem II.
Unshackled by expectations and lofty ambitions Salem deliver sublime pop punk jams for people whose hobbies include oujia boards and vampire fan fiction.
This is a band who penned the impossibly cool DRACULADS after all.Sounding like the soundtrack to a back alley fight between punks & greasers, it lives up to every bit of promise it's name suggests.
Keep The Thorns is an ode to doomed love and deals in the kind of widescreen melodrama that put Creeper on the map. Sweet Tooth is one of the catchiest songs you'll hear this year. It will burrow in your head and you'll probably need to perform an exorcism to remove it.
Heaven Help Me brings the e.p to a close in storming fashion, with a 2 minute burst of punk rock bliss that will give you whiplash but leave you wanting more.
Over the course of 2 e.ps Salem have made quite the impression. Delivering some much needed fun in dark times, as well as providing some essential tracks to put on your summer goth playlist. You have to imagine somewhere Matt Skiba is playing with a voodoo doll of Will Gould, as he continues to make his claim for the crown prince of goth punk. Where Salem go from here is anyone's guess, but on the strength of these 2 e.p's alone, it's a journey i'd more than willing to join them on.
Salem II is out now via Roadrunner Records
salem II
A New Beginning: An Interview with Matthew Leone of Madina Lake: "Be yourself in any situation every time without exception."
Salem – Salem
Fever 333 – Wrong Generation
Corey Taylor – CMFT
Machine Gun Kelly – Tickets To My Downfall
Code Orange – Under the Skin
Special Feature With Trivium's Matt Heafy – A 2010's Retrospective in the Rock Sins 10 at 10 Series


text:
Q: External function calling for parent's "this" scope I have two .js files: root.js and external.js
root.js
import myExternalFunction from 'external.js'

class Parent {
    constructor(){}
    parentFunction = () => {
        console.log('I was called from an external function using "this."')
    }
}

external.js
export default myExternalFunction = () => {
    this.parentFunction()
}

Currently I receive an error about it not being a function, or no access to 'this'.
How do I import external functions that want to use the 'this' scope from which they are being called?

A:
How do I import external functions that want to use the 'this' scope from which they are being called?

It doesn't have anything to do with how you export/import the function.
There are two things you need to consider:

*

*functions that want to receive their this value dynamically must not be arrow functions, so use
export default function myExternalFunction() {
    this.parentFunction()
}

*as usual, the function must be invoked in the right way to get the expected this value. There's no magic that passes the current this value in the scope of the call to the called function. You'll have to do something like
import myExternalFunction from 'external.js'

class Parent {
    constructor(){
        this.method = myExternalFunction;
        this.parentFunction = () => {
            console.log('I was called from an external function using "this."')
        }
    }
}

const example = new Parent;
example.method() // an invocation as a method
myExternalFunction.call(example); // explicit using `call`