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The Sunday People reported that 'Nasty Nick' - Nick Bateman of the original UK series of Big Brother (2000) could be a housemate in January 2017's Celebrity Big Brother, which is rumoured to have a 'Gold Stars vs. New Stars' theme.
In the Big Brother 1 house in 2000, he was the only contestant not to receive a nomination. However, he became known as "Nasty Nick" because of his duplicitousness, manipulating his housemates into voting for each other. After 5 weeks he was finally confronted by the housemates who realised he was showing other housemates' names on pieces of paper to influence nominations. He was then asked to leave the house by the show's producers.
He also took part in 2005's Big Brother Panto shown on Channel 4, and in 2010's Ultimate Big Brother, where he struck up a friendship with Victor Ebuwe.
He made many media appearances after Big Brother 1, such as presenting his own show: 'Trust Me' on Channel 4 and appearing in pantomime. He currently lives in Sydney, Australia.
Other returning housemates (the 'Gold Stars' of the theme) rumoured for January's Celebrity Big Brother are Jasmine Leonard, James Jordan, Speidi and Stephen Bear.
Take a look at the Celebrity Big Brother 19 forum HERE for the latest discussion on the series.
Big Brother 1 (2000) forum and Ultimate Big Brother forum.
Nasty Nick is the latest name to be linked to Celebrity Big Brother 2017.
Nick Bateman was the show's original bad guy after finding himself ejected in Series 1.
He was kicked out for messing with nominations, which shows how much things have changed when people can now get away with spitting in another housemate's food. Ahem.
Anyway, it's been reported that Nick is one of the names set to return to the house as part of next January's All Star celebrity series, even if he was never a celebrity housemate.
The special run is set to celebrate CBB's 20th series, although that actually won't be until the summer.
A source told The Sunday People newspaper: "Even 16 years after the first series, fans of the show will remember his performance – he's one of the all time stars of the show.
If Nick does appear it would actually be his third Big Brother stint having previously competed in Channel 4's All Stars special Ultimate Big Brother in 2010.
Other names tipped to appear in January include James Jordan and Jasmine Lennard. As well as appearing in their original series, Jasmine and James also popped up in the house last year too as part of a 'Timebomb' twist.
However it won't just be familiar faces on the 'all stars' line up next year, if rumours are to be believed.
The Sun has suggested the name will in fact be 'Gold Stars vs New Stars' with a special series featuring both ex-housemates and new faces.
Celebrity Big Brother all star line up?
More names on a supposed 'wish list' include recent CBB winner Stephen Bear, professional troll Katie Hopkins, model and Loose Women star Katie Price and US couple Spencer Pratt and Heidi Montag.
Celebrity Big Brother 2017 will on Channel 5 in the new year.
Nasty Nick and not Charley?
He wasn't, it was just good to see him have redemption. He's had that now, his story's done, so there's no need for him to go in again since he's not actually that entertaining.
If they do it, they should stick to c5 celebs, but then again Bear exists so probably na dont do it.
He was so boring in UBB but i'd rather him than Hopkins, James Jordan and Bear.
He was so boring in UBB, he'd be a waste of a housemate here.


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Journal of Nucleic Acids
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Complete Special Issue
Volume 2010, Article ID 304035, 11 pages
Targeting the OB-Folds of Replication Protein A with Small Molecules
Victor J. Anciano Granadillo,1 Jennifer N. Earley,1 Sarah C. Shuck,1,2,3 Millie M. Georgiadis,2 Richard W. Fitch,4 and John J. Turchi1,2
1Department of Medicine/Hematology and Oncology, Indiana University School of Medicine, Joseph E. Walther Hall, R3-C562, 980 W. Walnut Street, Indianapolis, IN 46202, USA
2Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Joseph E. Walther Hall, R3-C562, 980 W. Walnut Street, Indianapolis, IN 46202, USA
3Department of Biochemistry, Vanderbilt University School of Medicine, 850 Robinson Research Building, Nashville, TN 37209, USA
4Department of Chemistry and Physics, Indiana State University, Terre Haute, IN 47809, USA
Received 19 August 2010; Accepted 27 September 2010
Academic Editor: Ashis Basu
Copyright © 2010 Victor J. Anciano Granadillo et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
M. S. Wold, "Replication protein A: a heterotrimeric, single-stranded DNA-binding protein required for eukaryotic DNA metabolism," Annual Review of Biochemistry, vol. 66, pp. 61–92, 1997. View at Publisher · View at Google Scholar
A. Bochkarev and E. Bochkareva, "From RPA to BRCA2: lessons from single-stranded DNA binding by the OB-fold," Current Opinion in Structural Biology, vol. 14, no. 1, pp. 36–42, 2004. View at Publisher · View at Google Scholar · View at Scopus
D. L. Theobald, R. M. Mitton-Fry, and D. S. Wuttke, "Nucleic acid recognition by OB-fold proteins," Annual Review of Biophysics and Biomolecular Structure, vol. 32, pp. 115–133, 2003. View at Publisher · View at Google Scholar · View at Scopus
M. Lei, E. R. Podell, and T. R. Cech, "Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection," Nature Structural & Molecular Biology, vol. 11, no. 12, pp. 1223–1229, 2004. View at Google Scholar · View at Scopus
F. Wang, E. R. Podell, A. J. Zaug et al., "The POT1-TPP1 telomere complex is a telomerase processivity factor," Nature, vol. 445, no. 7127, pp. 506–510, 2007. View at Publisher · View at Google Scholar · View at Scopus
H. Yang, P. D. Jeffrey, J. Miller et al., "BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure," Science, vol. 297, no. 5588, pp. 1837–1848, 2002. View at Publisher · View at Google Scholar · View at Scopus
A. G. Murzin, "OB(oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences," EMBO Journal, vol. 12, pp. 861–867, 1993. View at Google Scholar
E. Bochkareva, S. Korolev, S. P. Lees-Miller, and A. Bochkarev, "Structure of the RPA trimerization core and its role in the multistep DNA-binding mechanism of RPA," EMBO Journal, vol. 21, no. 7, pp. 1855–1863, 2002. View at Publisher · View at Google Scholar · View at Scopus
R. A. Pfuetzner, A. Bochkarev, L. Frappier, and A. M. Edwards, "Replication protein A: characterization and crystallization of the DNA binding domain," Journal of Biological Chemistry, vol. 272, no. 1, pp. 430–434, 1997. View at Publisher · View at Google Scholar · View at Scopus
K. Umezu, N. Sugawara, C. Chen, J. E. Haber, and R. D. Kolodner, "Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism," Genetics, vol. 148, no. 3, pp. 989–1005, 1998. View at Google Scholar · View at Scopus
S. J. Haring, A. C. Mason, S. K. Binz, and M. S. Wold, "Cellular functions of human RPA1: multiple roles of domains in replication, repair, and checkpoints," Journal of Biological Chemistry, vol. 283, no. 27, pp. 19095–19111, 2008. View at Publisher · View at Google Scholar · View at Scopus
S. C. Shuck and J. J. Turchi, "Targeted inhibition of Replication Protein A reveals cytotoxic activity, synergy with chemotherapeutic DNA-damaging agents, and insight into cellular function," Cancer Research, vol. 70, no. 8, pp. 3189–3198, 2010. View at Publisher · View at Google Scholar
S. Waga and B. Stillman, "The DNA replication fork in eukaryotic cells," Annual Review of Biochemistry, vol. 67, pp. 721–751, 1998. View at Publisher · View at Google Scholar · View at Scopus
I. de Vlaminck, I. Vidic, M. T. J. van Loenhout, R. Kanaar, J. H. G. Lebbink, and C. Dekker, "Torsional regulation of hRPA-induced unwinding of double-stranded DNA," Nucleic Acids Research, vol. 38, no. 12, pp. 4133–4142, 2010. View at Publisher · View at Google Scholar
D. B. Zamble, D. Mu, J. T. Reardon, A. Sancar, and S. J. Lippard, "Repair of cisplatin-DNA adducts by the mammalian excision nuclease," Biochemistry, vol. 35, no. 31, pp. 10004–10013, 1996. View at Publisher · View at Google Scholar · View at Scopus
S. M. Patrick and J. J. Turchi, "Xeroderma pigmentosum complementation group A protein (XPA) modulates RPA-DNA interactions via enhanced complex stability and inhibition of strand separation activity," Journal of Biological Chemistry, vol. 277, no. 18, pp. 16096–16101, 2002. View at Publisher · View at Google Scholar · View at Scopus
S. M. Patrick and J. J. Turchi, "Replication protein a (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA," Journal of Biological Chemistry, vol. 274, no. 21, pp. 14972–14978, 1999. View at Publisher · View at Google Scholar · View at Scopus
S. M. Patrick, K. Tillison, and J. M. Horn, "Recognition of cisplatin-DNA interstrand cross-links by replication protein A," Biochemistry, vol. 47, no. 38, pp. 10188–10196, 2008. View at Publisher · View at Google Scholar · View at Scopus
E. Reed, "Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy," Cancer Treatment Reviews, vol. 24, no. 5, pp. 331–344, 1998. View at Google Scholar
M. E. Stauffer and W. J. Chazin, "Physical interaction between replication protein A and Rad51 promootes exchange on single-stranded DNA," Journal of Biological Chemistry, vol. 279, no. 24, pp. 25638–25645, 2004. View at Publisher · View at Google Scholar · View at Scopus
C. Soustelle, M. Vedel, R. Kolodner, and A. Nicolas, "Replication protein A is required for meiotic recombination in Saccharomyces cerevisiae," Genetics, vol. 161, no. 2, pp. 535–547, 2002. View at Google Scholar · View at Scopus
J. J. Turchi, S. C. Shuck, E. A. Short, and B. J. Andrews, "Targeting nucleotide excision repair as a mechanism to increase cisplatin efficacy," in Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy, A. Bonetti, R. Leone, F. M. Muggia, and S. B. Howell, Eds., Humana Press, New York, NY, USA, 2009. View at Google Scholar
B. J. Andrews, J. A. Lehman, and J. J. Turchi, "Kinetic analysis of the Ku-DNA binding activity reveals a redox-dependent alteration in protein structure that stimulates dissociation of the Ku-DNA complex," Journal of Biological Chemistry, vol. 281, no. 19, pp. 13596–13603, 2006. View at Publisher · View at Google Scholar · View at Scopus
B. J. Andrews and J. J. Turchi, "Development of a high-throughput screen for inhibitors of replication protein A and its role in nucleotide excision repair," Molecular Cancer Therapeutics, vol. 3, no. 4, pp. 385–391, 2004. View at Google Scholar · View at Scopus
I. M. Wyka, K. Dhar, S. K. Binz, and M. S. Wold, "Replication Protein A interactions with DNA: differential binding of the core domains and analysis of the DNA interaction surface," Biochemistry, vol. 42, no. 44, pp. 12909–12918, 2003. View at Publisher · View at Google Scholar · View at Scopus
E. Bochkareva, V. Belegu, S. Korolev, and A. Bochkarev, "Structure of the major single-stranded DNA-binding domain of replication protein A suggests a dynamic mechanism for DNA binding," EMBO Journal, vol. 20, no. 3, pp. 612–618, 2001. View at Publisher · View at Google Scholar · View at Scopus
A. Bochkarev, R. A. Pfuetzner, A. M. Edwards, and L. Frappier, "Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA," Nature, vol. 385, no. 6612, pp. 176–181, 1997. View at Publisher · View at Google Scholar · View at Scopus
R. I. Murray, I. C. Gunsalus, and K. M. Dus, "Active site studies of cytochrome P=450CAM. I. Specific cysteine labeling with the affinity reagent isobornyl bromoacetate as a model for substrate binding," Journal of Biological Chemistry, vol. 257, no. 21, pp. 12517–12525, 1982. View at Google Scholar · View at Scopus
M. Lei, E. R. Podell, P. Baumann, and T. R. Cech, "DNA self-recognition in the structure of Pot1 bound to telomeric single-stranded DNA," Nature, vol. 426, no. 6963, pp. 198–202, 2003. View at Publisher · View at Google Scholar · View at Scopus
J. E. Croy, E. R. Podell, and D. S. Wuttke, "A new model for schizosaccharomyces pombe telomere recognition: the telomeric single-stranded DNA-binding Activity of Pot11-389," Journal of Molecular Biology, vol. 361, no. 1, pp. 80–93, 2006. View at Publisher · View at Google Scholar · View at Scopus
S. Raghunathan, A. G. Kozlov, T. M. Lohman, and G. Waksman, "Structure of the heterodimeric complex between CAD domains of CAD and ICAD," Nature Structural Biology, vol. 7, no. 8, pp. 658–662, 2000. View at Publisher · View at Google Scholar · View at Scopus
P. Y. Ng, Y. Tang, W. M. Knosp, H. S. Stadler, and J. T. Shaw, "Synthesis of diverse lactam carboxamides leading to the discovery of a new transcription-factor inhibitor," Angewandte Chemie, vol. 46, no. 28, pp. 5352–5355, 2007. View at Publisher · View at Google Scholar · View at Scopus
R. E. Moellering, M. Cornejo, T. N. Davis et al., "Direct inhibition of the NOTCH transcription factor complex," Nature, vol. 462, no. 7270, pp. 182–188, 2009. View at Publisher · View at Google Scholar · View at Scopus
M. N. Saha, H. Jiang, J. Jayakar, D. Reece, D. R. Branch, and H. Chang, "MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity," Cancer Biology and Therapy, vol. 9, no. 11, pp. 937–945, 2010. View at Google Scholar

redpajama_set_name: RedPajamaCommonCrawl


text:
Lynx names new non-executive director
Janine Brewis
Friday August 4, 2000 5:00 pm
Andrew Hawkins, a partner at venture capital firm Palomon Capital Partners, has been appointed as a non-executive director at Lynx Group, a software and systems provider.
At Palamon Capital, whose first round of financing of $440m (€482m) is targeted at investment in European growth companies, Hawkins is responsible for internet and technology matters.
Before...


text:
"""Support for Xiomi Gateway alarm control panels."""

from functools import partial
import logging

from miio import DeviceException

from homeassistant.components.alarm_control_panel import (
    SUPPORT_ALARM_ARM_AWAY,
    AlarmControlPanelEntity,
)
from homeassistant.const import (
    STATE_ALARM_ARMED_AWAY,
    STATE_ALARM_ARMING,
    STATE_ALARM_DISARMED,
)
from homeassistant.helpers.entity import DeviceInfo

from .const import CONF_GATEWAY, DOMAIN

_LOGGER = logging.getLogger(__name__)

XIAOMI_STATE_ARMED_VALUE = "on"
XIAOMI_STATE_DISARMED_VALUE = "off"
XIAOMI_STATE_ARMING_VALUE = "oning"

async def async_setup_entry(hass, config_entry, async_add_entities):
    """Set up the Xiaomi Gateway Alarm from a config entry."""
    entities = []
    gateway = hass.data[DOMAIN][config_entry.entry_id][CONF_GATEWAY]
    entity = XiaomiGatewayAlarm(
        gateway,
        f"{config_entry.title} Alarm",
        config_entry.data["model"],
        config_entry.data["mac"],
        config_entry.unique_id,
    )
    entities.append(entity)
    async_add_entities(entities, update_before_add=True)

class XiaomiGatewayAlarm(AlarmControlPanelEntity):
    """Representation of the XiaomiGatewayAlarm."""

    def __init__(
        self, gateway_device, gateway_name, model, mac_address, gateway_device_id
    ):
        """Initialize the entity."""
        self._gateway = gateway_device
        self._name = gateway_name
        self._gateway_device_id = gateway_device_id
        self._unique_id = f"{model}-{mac_address}"
        self._icon = "mdi:shield-home"
        self._available = None
        self._state = None

    @property
    def unique_id(self):
        """Return an unique ID."""
        return self._unique_id

    @property
    def device_id(self):
        """Return the device id of the gateway."""
        return self._gateway_device_id

    @property
    def device_info(self) -> DeviceInfo:
        """Return the device info of the gateway."""
        return DeviceInfo(
            identifiers={(DOMAIN, self._gateway_device_id)},
        )

    @property
    def name(self):
        """Return the name of this entity, if any."""
        return self._name

    @property
    def icon(self):
        """Return the icon to use for device if any."""
        return self._icon

    @property
    def available(self):
        """Return true when state is known."""
        return self._available

    @property
    def state(self):
        """Return the state of the device."""
        return self._state

    @property
    def supported_features(self) -> int:
        """Return the list of supported features."""
        return SUPPORT_ALARM_ARM_AWAY

    async def _try_command(self, mask_error, func, *args, **kwargs):
        """Call a device command handling error messages."""
        try:
            result = await self.hass.async_add_executor_job(
                partial(func, *args, **kwargs)
            )
            _LOGGER.debug("Response received from miio device: %s", result)
        except DeviceException as exc:
            _LOGGER.error(mask_error, exc)

    async def async_alarm_arm_away(self, code=None):
        """Turn on."""
        await self._try_command(
            "Turning the alarm on failed: %s", self._gateway.alarm.on
        )

    async def async_alarm_disarm(self, code=None):
        """Turn off."""
        await self._try_command(
            "Turning the alarm off failed: %s", self._gateway.alarm.off
        )

    async def async_update(self):
        """Fetch state from the device."""
        try:
            state = await self.hass.async_add_executor_job(self._gateway.alarm.status)
        except DeviceException as ex:
            if self._available:
                self._available = False
                _LOGGER.error("Got exception while fetching the state: %s", ex)

            return

        _LOGGER.debug("Got new state: %s", state)

        self._available = True

        if state == XIAOMI_STATE_ARMED_VALUE:
            self._state = STATE_ALARM_ARMED_AWAY
        elif state == XIAOMI_STATE_DISARMED_VALUE:
            self._state = STATE_ALARM_DISARMED
        elif state == XIAOMI_STATE_ARMING_VALUE:
            self._state = STATE_ALARM_ARMING
        else:
            _LOGGER.warning(
                "New state (%s) doesn't match expected values: %s/%s/%s",
                state,
                XIAOMI_STATE_ARMED_VALUE,
                XIAOMI_STATE_DISARMED_VALUE,
                XIAOMI_STATE_ARMING_VALUE,
            )
            self._state = None

        _LOGGER.debug("State value: %s", self._state)

redpajama_set_name: RedPajamaGithub


text:
Purdue University Programming Languages Group
News Openings People Research Courses Seminars
Programming Eventually Consistent Data Stores
Geo-distributed web applications often favor high availability over strong consistency. In response to this bias, modern-day replicated data stores often eschew sequential consistency in favor of weaker eventual consistency (EC) data semantics. While most operations supported by a typical web application can be engineered, with sufficient care, to function under EC, there are oftentimes critical operations that require stronger consistency guarantees. Unfortunately, existing approaches to tunable consistency suffers from poorly-defined implementation-specific semantics, often expressed at a level of abstraction far removed from the application. The Quelea project addresses these concerns by defining a declarative programming model for EC data stores that abstracts the actual implementation of the data store via high-level programming and system-level models that are agnostic to a specific implementation. By using Quelea, programmers can reason in terms of an abstract model of the data store, and develop applications by defining and composing high-level replicated data types. Any EC key-value store can support Quelea by implementing a thin shim layer and a choosen set of high-level consistency guarantees on top of its existing low-level interface.
Representative publications:
Representation Without Taxation: A Uniform, Low-Overhead High-Level Interface to Eventually Consistent Key-Value Stores
Declarative Programming Over Eventually Consistent Data Stores
Automatically optimizing irregular applications
This project focuses on developing frameworks to automatically analyze, transform and tune irregular applications, which operate over pointer-based data structures, to improve their locality, parallelism and performance. While irregular applications seemingly have little commonality, this project is premised on the insight that at higher levels of abstractions, there are common behaviors in irregular applications that can be exploited to develop automatic transformations to enhance performance.
Locality Transformations for Nested Recursive Iteration Spaces
TreeFusor: A Framework for Analyzing and Fusing General Recursive Tree Traversals
Quantitative Program Repair for Education
Can we build effective tools for personalized feedback and evaluation of assignments based on inferring "optimal" repairs for student solutions? Can we learn appropriate objective functions, program distances and error models to use for repair from existing databases of assignments? In this project, we are investigating the use of quantitative program repair, along with machine learning, for automated feedback and grading.
Cost-Aware Automatic Program Repair
Qlose: Program Repair with Quantitative Objectives
Lightweight Modular Staging
Recent years have seen a surge of interest in staging and generative programming, driven by the increasing difficulty of making high-level code run fast on modern hardware. While the mechanics of program generation are relatively well understood, we have only begun to understand how to develop systems in a generative way. The Lightweight Modular Staging (LMS) platform forms the core of a research agenda to make generative programming more widely accessible, through powerful libraries and a growing selection of case studies that illuminate design patterns and crystallize best practices for high-level and effective generative programming. As an example, LMS has been applied to speed up data processing and query engines. The most recent work in this direction is Flare, an accelerator back-end for Apache Spark that achieves order of magnitude speedups by compiling SQL and data frame queries to native code.
Collapsing Towers of Interpreters
Go Meta! A Case for Generative Programming and DSLs in Performance Critical Systems
Deductive Synthesis of Correct-by-Construction Programs
The goal of program synthesis is to automatically produce the implementation of a program from a high-level specification its behavior. Fiat is a synthesis framework for the Coq proof assistant that combines foundational ideas from programming language and formal methods to build an automated refinement system from first principles capable produces correct-by-construction sofware with a minimal trusted code base. Starting from high-level specifications in Coq's rich logic, Fiat helps users interactively construct an executable implementation. Every step in the process is justified by a machine-checked refinement proof which, when composed together, certifies that the derived implementation meets the original specification. The framework provides libraries of domain-specific specification languages and reusable refinement tactics for guiding the search for an implementation, leveraging Coq's powerful Ltac metaprogramming language to achieve a high degree of automation. Each refinement step is certified by Coq, allowing users to freely incorporate their own implementation strategies into a derivation without compromising the guarantees of its correctness.
The End of History? Using a Proof Assistant to Replace Language Design with Library Design
Using Coq to Write Fast and Correct Haskell
Program verification via Natural Proofs
Reliability is critical for system software, such as OS kernels and mobile browsers, as well as applications such as office software and mail clients. The correctness of these programs, especially for security, is highly desirable, as they should provide a trustworthy platform for higher-level applications and the end-users. Unfortunately, due to its inherent complexity, the verification process of these programs is typically manual/semi-automatic, tedious, and painful. Natural proofs help to automate the reasoning behind these verification tasks and decrease the dependence on manual help. As a sound but incomplete verification technique, the essence of natural proofs is to identify and automate a fixed set of simple but useful proof tactics, and algorithmically search for a proof that only uses these tactics. Due to the simplicity and usefulness of these tactics, the search process is decidable, very efficient and tends to be successful.
Natural proofs for structure, data, and separation.
Natural synthesis of provably-correct data-structure manipulations.


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text:
Q: How to add numbers for a string sentence in Java? I want to add numbers using Java.
For example, the sentence is given String: "My age is 50, and your age is under 30." If I want to add 5 to the sentence, it should be like
"My age is 55, and your age is under 35."
The restriction is the sentence is given, so you need to extract numbers from the sentence and add the numbers to the original sentence.
I was trying to split by space (" ") and try to add numbers after that.
But I don't know how to substitute numbers with the original sentence.
I am confused since it has comma when I am trying to split by " " and even if you can extract all the numbers from the sentence, I am not sure how can I get back to numbers to string.
public class Main {

public static Pattern pattern = Pattern.compile("\\d+");

public static String addNumber(String str, int n) {

    Matcher matcher = pattern.matcher(str);
    if (matcher.find()) {
        String theAge = matcher.group(0);
        int newAge = Integer.parseInt(theAge) + n;
    }

    String addSentence = str;

    return addSentence;
}

public static void main(String[] args) {
    String testString = "My age is 50, and your age is under 30.";
    String testString2 = "My age is 50, and your age is under 30 and my friend age is 44.";

    String newSent = addNumber(testString, 5);
    // -> should be "My age is 55, and your age is under 35.
    String newSent2 = addNumber(testString2, 10);
    // -> should be "My age is 60, and your age is under 40 and my friend age is 54.";

}

}
enter code here

A: You can format your string using printf(),
int myAge = 50;
int yourAge = 30;

System.out.printf("My age is %d, and your age is under %d.", myAge, yourAge);

// add five
myAge += 5;
yourAge += 5;

System.out.printf("My age is %d, and your age is under %d.", myAge, yourAge);

The output will be,
"My age is 50, and your age is under 30."
"My age is 55, and your age is under 35."

A: Use regex API as follows:
import java.util.regex.Matcher;
import java.util.regex.Pattern;

public class Main {
    public static void main(String[] args) {
        String str = "My age is 50, and your age is under 30.";

        // The number to be added
        int n = 5;

        Pattern pattern = Pattern.compile("\\d+");
        Matcher matcher = pattern.matcher(str);
        while (matcher.find()) {
            str = str.replace(matcher.group(), String.valueOf(Integer.parseInt(matcher.group()) + n));
        }

        // Display
        System.out.println(str);
    }
}

Output:
My age is 55, and your age is under 35.

A: int myAge = 50;
int yourAge = 30;
String msgStr = "My age is %d, and your age is under %d.";
System.out.printLn(String.format(msgStr, myAge, yourAge));
System.out.printLn(String.format(msgStr, myAge+5, yourAge+5));

A: Store age1 and age2 as variables and use a separate int for increment string to output the result.
For example:
public int addToString(int increment, int age1, int age2){

String s = "My age is " +(age1 + inc)+ " , and your age is under " +(age2 + inc);

return s; //addToString(5, 50,30) returns: "My age is 55, and your age is under 35"
}

A: You have 2 ways. If the string is created by you you can use:
    int age = 50;
    String s = String.format("My age is %d, and your age is under 30.", age);

Otherwise I suggest something like a regex to pick the numbers and rewrite the string. For instance:
class Scratch {
static Pattern pattern = Pattern.compile("\\d+");

public static void main(String[] args) {
    String string = "My age is 50, and your age is under 30.";
    Matcher matcher = pattern.matcher(string);

    if (matcher.find()) {
        String theAge = matcher.group(0);
    }
  }
}

A: You are given a string. The string may contain numbers. You want to add the same increment to each number that appears in the string. And you want to replace each number appearing in the string with that same number plus the increment.
I suggest using java regular expressions, in particular method replaceAll() which was added in Java 9. Here is the code.
import java.util.function.Function;
import java.util.regex.MatchResult;
import java.util.regex.Matcher;
import java.util.regex.Pattern;

public class Main {

    public static void main(String[] args) {
        String str = "My age is 50, and your age is under 30.";
        if (args.length > 0) {
            str = args[0];
        }
        int temp = 5;
        if (args.length > 1) {
            temp = Integer.parseInt(args[1]);
        }
        final int increment = temp;
        Pattern pattern = Pattern.compile("\\d+");
        Matcher matcher = pattern.matcher(str);
        Function<MatchResult, String> replacer = new Function<MatchResult, String>() {
            public String apply(MatchResult matchResult) {
                String str = matchResult.group();
                int val = Integer.parseInt(str);
                val += increment;
                return String.valueOf(val);
            }
        };
        String result = matcher.replaceAll(replacer);
        System.out.println(result);
    }
}

Note that since java.util.function.Function is a functional interface, you can use a lambda expression which may make the code shorter but I think the code above is easier to understand. Here is the result of running the above code.
My age is 55, and your age is under 35.

redpajama_set_name: RedPajamaStackExchange


text:
VAC — трёхбуквенная аббревиатура, в зависимости от контекста может означать:
 англ. Volts alternating current — напряжение переменного тока.
  — волейбольная команда им. Адилет.
  — разработка компании Valve для предотвращения использования игроками читов.
  — мультимедийный драйвер для Windows, позволяющий перенаправлять аудиопотоки между приложениями.
  — в индийской мифологии богиня речи, персонификация речи.
  — город Вац в центральной части Венгрии.
  — музыкальная группа из США, играющая электро-индастриал
  — Министерство по делам ветеранов Канады
  — переменный ток.
 VAC — акроним для одного из режимов химиотерапии, основанного на применении винкристина — (V)incristine, дактиномицина — (A)ctinomycin D, и дексаметазона — (D)examethasone.
 VAC (''Vacancy) — Сокращение в среде гостиничного бизнеса, обозначающее, что конкретный номер в отеле свободен.

redpajama_set_name: RedPajamaWikipedia


text:
AirPlay Reverse Engineered to Send Video From iOS Devices to Macs
Tuesday December 14, 2010 1:00 pm PST by Eric Slivka
While Apple's AirPlay feature introduced in iOS 4.2 allows users to stream certain video content from their iOS devices to the new Apple TV, users have been wondering if the service will ever be extended to allow content to be streamed to their Macs in a similar fashion. In addressing the question of whether such an implementation would be difficult, TUAW's Erica Sadun has put together an alpha version of a Mac OS X application known as "AirPlayer" that does exactly that.
What AirPlayer does is create and advertise a custom Bonjour AirPlay service that pretends to be an Apple TV. Bonjour is Apple's zero configuration networking solution for allowing devices and applications to communicate with each other over local area networks. When Apple created AirPlay, it basically set up a new way for Apple TV to interact with iOS using Bonjour communications.
The functionality could in theory also be supported on Windows PCs as Apple offers Bonjour for Windows, although Sadun notes that she is not likely to attempt to build a Windows version anytime soon.
Interested users can download the ad-supported alpha version for Mac OS X from Sadun's website to test out the functionality. Users' iOS devices do not need to be jailbroken for the functionality to work, although some tools such as AirVideoEnabler that can extend AirPlay functionality to more iOS apps do require jailbreaking.
AirPlayer remains an early proof-of-concept release, and users are of course advised that there may be bugs and other quirks associated with the application.


This two-day hands-on workshop is guaranteed to boost profits and increase cash flow in your firm.
More work is coming in the door, you are bringing on more new hires to meet client demand, and it seems that you are seeing respectable revenue growth again.
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What happens two weeks after a new employee fills out her time sheet? She expects a paycheck. Have you been paid by the clients for the time she spent on their projects? Nope. In fact, you haven't even sent out the invoice yet. Two weeks later, she expects to be paid again... and then again.
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Participants in this unique and action-oriented program come from a wide range of backgrounds…from the experienced finance professional who is new to the A/E/C world to the experienced A/E/C professional who is new to the finance world and everyone in between.
Because of the interactive nature of this program, we consistently hear from past attendees that bringing their colleagues significantly amplified the value. That is because we group attendees into teams for various workshops. By bringing two (or more) of your colleagues, we can set you up as a team focused on your firm and your challenges. Hit the ground running when you get back to the office.
We all know that finance can be messy. Just covering some basic definitions or a speaker going on and on speaking AT you on all things finance is an easy way to get to glazed-over eyes and no tangible changes back at the office.
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Workshop: How Much Financial Information Should You Share?
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We frequently offer our popular training programs in partnership with state and local association chapters. These partnership programs are a great way to bring high-value and relevant content to association members and an easy way to generate non-dues revenue for associations!
If you would like to learn more about our association partnership programs, click here.
Your registration at this Workshop includes instruction, a workbook, unrestricted access to our Financial Management Digital Toolbox (a $497 value), and continental breakfast, lunch, and coffee breaks on both days.
Of course, like all PSMJ programs, this Workshop includes our 100% money back guarantee. If, for any reason at all, you are not completely satisfied with the value that you receive from this Workshop, just let us know and we'll refund your registration fee. Every penny. No questions asked.
- When you register 60+ days before a program date, you SAVE $400!
- When you register between 30 and 59 days before a program date, you SAVE $200!
This Workshop is AIA CES-registered to provide this content. This Workshop earns you up to 13 LU Hours, CEUs, or PDHs. Not all state and licensing boards accept these programs for learning units. PSMJ is a registered provider with the Florida Board of Professional Engineers (provider #0007694). PSMJ is a registered provider with the Florida Board of Landscape Architects (provider #0002844 course #0007693).
PSMJ programs are registered with the National Association of State Boards of Accountancy (NASBA) as a sponsor of continuing professional education on the National Registry of CPE Sponsors. State boards of accountancy have final authority on the acceptance of individual courses for CPE credit. Complaints regarding registered sponsors may be submitted to the National Registry of CPE Sponsors through its website: www.nasbaregistry.org. PSMJ education programs Sponsor ID number is 107567. This course qualifies for 13 CPE credits.
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text:
Q: Installing h5py mpi in Windows with Visual Studio I've been trying to install h5py but I've got a problem with the setup. I'm  trying to follow the guide explained http://docs.h5py.org/en/stable/build.html#custom-installation
I first set on Powershell:
$env:HDF5_MPI="ON"

and then run the command
pip install --no-binary=h5py  h5py

which gives me the following output at the end (there is more before the beginning of the following snippet):
warning: h5py\api_types_hdf5.pxd:732:6: 'H5Z_ENABLE_EDC' redeclared
    warning: h5py\api_types_hdf5.pxd:733:6: 'H5Z_NO_EDC' redeclared
    building 'h5py.defs' extension
    creating build\temp.win-amd64-3.6
    creating build\temp.win-amd64-3.6\Release
    creating build\temp.win-amd64-3.6\Release\Users
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele\AppData
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele\AppData\Local
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele\AppData\Local\Temp
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py
    creating build\temp.win-amd64-3.6\Release\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py\h5py
    C:\Program Files (x86)\Microsoft Visual Studio\2017\BuildTools\VC\Tools\MSVC\14.16.27023\bin\HostX86\x64\cl.exe /c /nologo /Ox /W3 /GL /DNDEBUG /MD -DH5_USE_16_API -D_HDF5USEDLL_ -DH5_BUILT_AS_DYNAMIC_LIB -I.\h5py -IC:\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py\lzf -IC:\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py\windows -IC:\Users\bdaniele\framework\venv\Lib\site-packages\numpy\core\include -IC:\Users\bdaniele\framework\venv\Lib\site-packages\mpi4py\include -Ic:\users\bdaniele\appdata\local\continuum\anaconda3\include -Ic:\users\bdaniele\appdata\local\continuum\anaconda3\include "-IC:\Program Files (x86)\Microsoft Visual Studio\2017\BuildTools\VC\Tools\MSVC\14.16.27023\include" "-IC:\Program Files (x86)\Windows Kits\10\include\10.0.17763.0\ucrt" "-IC:\Program Files (x86)\Windows Kits\10\include\10.0.17763.0\shared" "-IC:\Program Files (x86)\Windows Kits\10\include\10.0.17763.0\um" "-IC:\Program Files (x86)\Windows Kits\10\include\10.0.17763.0\winrt" "-IC:\Program Files (x86)\Windows Kits\10\include\10.0.17763.0\cppwinrt" /TcC:\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py\h5py\defs.c /Fobuild\temp.win-amd64-3.6\Release\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py\h5py\defs.obj
    defs.c
    C:\Users\bdaniele\AppData\Local\Temp\pip-install-gmwxxuog\h5py\h5py\defs.c(634): fatal error C1083: Cannot open include file: 'mpi.h': No such file or directory
    error: command 'C:\\Program Files (x86)\\Microsoft Visual Studio\\2017\\BuildTools\\VC\\Tools\\MSVC\\14.16.27023\\bin\\HostX86\\x64\\cl.exe' failed with exit status 2

I am able to compile and run programs using the same compiler with parallel tools enabled (MPI, OpenMP) without any problems. The documentation of h5py does not explain how to setup h5py on Windows using Visual Studio.
I don't have admin rights.
I would like to use this package with the MPI option enabled because I would like to read and write in parallel eventually (example: http://docs.h5py.org/en/stable/mpi.html#using-parallel-hdf5-from-h5py), and this feature seems to be installed with h5py.
What can I do to solve this problem?
Thanks!
Update:
After adding the paths for the MPI and HDF5 libraries in the setup_build.py file I was able to install h5py. However, when I try to run a python script, I get an error when importing h5py:
Traceback (most recent call last):
  File ".\testparh5.py", line 2, in <module>
    import h5py
  File "C:\Users\bdaniele\AppData\Local\Continuum\anaconda3\lib\site-packages\h5py-2.9.0.post0-py3.6-win-amd64.egg\h5py\__init__.py", line 26, in <module>
    from . import _errors
  File "MPI.pxd", line 62, in init h5py._errors
ValueError: mpi4py.MPI.Message size changed, may indicate binary incompatibility. Expected 40 from C header, got 32 from PyObject

Is it related to the mpi4py or other packages?


On Saturday, December 3rd, FFWPU and WFWP of Vienna conducted a one-day Divine Principle workshop in Seebenstein. Several Tribal Messiah families from Vienna and the surrounding area invited their guests for the workshop, so that we could have 21 adult guests and 4 children all together.
The purpose of the workshop was to prepare couples for the Blessing. The lectures contained the Principle of Creation, the Fall and the restoration, including an explanation about the Blessing. One couple who had been pre-blessed some years before is ready to go through all stages of the Blessing. Other guests showed interest as well.
The lectures were given by Dr. Wolfgang Czerny, Johannes Stampf and Elisabeth Cook.
All together we were a group of 40 persons, and a vivid and joyful atmosphere developed during the workshop which made it easy to convey the content of the Divine Principle lectures.
After the lectures two brothers, Dr. Czerny and Albert Heitzinger, gave a short testimony about their Blessing. Interesting enough the guests liked these testimonies most. Thank you Heavenly Parents and brothers and sisters for your hard work!


Below is the solution for Unfilled pie crust crossword clue. This clue was last seen on Oct 21 2018 in the Newsday crossword puzzle. While searching our database we found 1 possible solution matching the query "Unfilled pie crust". Please check the answer provided below and if its not what you are looking for then head over to the main post and use the search function. You can always go back at Newsday Crossword Puzzles crossword puzzle and find the other solutions for today's crossword clues.


text:
Newhill Cottage, Kennels & Cattery
Glassarts, Auchtermuchty, Cupar, Fife, KY14 7HT
Attractive cottage in a delightful rural setting
Two reception rooms, three bedrooms, kitchen/dining room.
Currently operating as a commercial kennels and cattery.
Extensive kennel outbuildings and cattery buildings
Double garage, two summer houses.
Delightful rural setting adjacent to Pitmedden Forest.
Central location ideal for the commuter
Newhill Cottage, Kennels and Cattery is situated in an idyllic position adjacent to Pitmedden Forest, a short distance to the northwest of Auchtermuchty in Fife. The village community provides a good range of local shops, services and amenities together …
Newhill Cottage, Kennels and Cattery is situated in an idyllic position adjacent to Pitmedden Forest, a short distance to the northwest of Auchtermuchty in Fife. The village community provides a good range of local shops, services and amenities together with a primary school. A wider offering of facilities is on hand just a ten minute drive to the east in Cupar, Fife's bustling county market town. With its new city status Perth is no more than a 17 mile drive from the property whilst a similar distance to the east lies the ancient and historic University Town of St Andrews, renowned worldwide as the "Home of Golf" with its wonderful mix of shops, restaurants and facilities. The vibrant City of Dundee is a comfortable drive from the village with Edinburgh well within commuting distance.
The surrounding countryside comprises a glorious mix of farmland, woodland, hill and river with the adjacent Pitmedden Forest giving access to over 1000 acres of woodland and an excellent network of paths suitable for hiking, orienteering, cycling and walking. The area is also home to an array of wildlife such as deer, red squirrels, woodpeckers and owls. Golfers have plenty of choice with many highly rated courses within easy reach including Ladybank, Lundin Links, Elie and the many fine courses in and around St Andrews where the Old Course is next due to host the British Open in 2022 for its 150th anniversary.
State schooling is available locally (with transport from the property), with private schooling being provided at St Leonards in St Andrews, Dollar Academy and the High School at Dundee. There are railway stations in Ladybank, Cupar, Leuchars and Perth with Edinburgh airport about 45 minutes to the south.
Newhill Cottage, Kennels and Cattery comprises an attractive detached cottage with good kennels and cattery facilities. Of a harled exterior under a slate roof with extension to the rear, the cottage offers deceptively spacious accommodation comprising well-proportioned sitting room with stove, garden/family room, modern kitchen/dining room, three bedrooms, family bathroom and hall. Within the garden grounds are a range of kennel and cattery buildings along with further ancillary buildings and double garage. The current owner of Newhill is currently operating a kennels/cattery business but interested parties would need to make their own enquiries in this regard in relation to licencing and such like. It is understood that the kennels have been established for over 30 years.
Sitting room, garden/family room, kitchen/dining room, three bedrooms, bathroom, hall, vestibule.
The garden at Newhill is of a reasonable size offering off road parking, areas of lawn and a mix of plants trees and shrubs. Large sections of the garden are presently turned over to the kennel and cattery operations.
Take the A91 into the village of Auchtermuchty and turn at the sign for Newburgh into Burnside and continue out of the village on the B936 in the direction of Lindores and Newburgh. About 1 mile beyond the village boundary take the turning on the left signposted for Glassarts and after a short distance take the left fork in the road and continue up the hill for about 500 metres. Newhill Cottage, Kennels and Cattery is then on the right-hand side.
KY14 7HT
No items are included unless specifically mentioned in these particulars.
Dominic Wedderburn
dominic.wedderburn@galbraithgroup.com


The Congressional Budget Office recently released statistics related to 2011 that offer a glimmer of hope related to the Federal Budget Deficit. Had it not been for unusual timing issues affecting the payments and receipts specific to 2011, there would have been an approximate $140 billion decrease in the deficit. This is in large part due to increased revenues from individual income tax payments that rose 6.5% over 2010 even as corporate and payroll taxes fell. Further, though 2011 spending roughly matched 2010, both years' spending was less than 2009 by approximately 1.1% of GDP. Both of these trends over a glimmer of hope as 2011 wraps up, and we head into the new year.


Just in time for the holidays, it's big rig action and guys punching each other out.
The tiny Canadian town of Willow Creek is in desperate straits--the canning company has closed and it's going to be a bleak holiday for the townsfolk.
Back in California, good guy Al (Hoyt Axton, appealingly warm in a too-small guest star role) is planning on taking a truck full of presents to Willow Creek as a surprise. Al gets sick, however, and it's up to brothers Ray and Pete (Schneider and Wopat) to drive the huge rig.
Problem is, Ray and Pete hate each other. See, Pete was going with Jessie (Kim Delaney), but she married Ray. Ray is a free spirit who likes country music; Pete is dull and responsible and listens to opera. Pete also has a son named Mike (Zacharay Ansley) who has green hair and listens to heavy rock and who would rather have Ray for a dad . . .
Will they make it to Willow Creek? Will Mike change the color of his hair? Will Jessie and Ray get back together? Will Pete admit he taps his foot to country music? Will there be lots of fistfights?
It's all pretty silly and it gets sillier. Paul Beckett, as a mysterious sheep herder who helps deliver Jessie's baby in a snow storm, asks Mike to help by saying, "I need someone to stroke the ewe."
And somehow the thankful tears on the faces of the Willow Creek children as they receive their Christmas presents aren't as moving as they might be--the gifts are G.I. Joe dolls and robot cars.


text:
Why California isn't banking on electric cars to replace public transit in greener future
In this Tuesday, Feb. 25, 2020 file photo, robots work on an electric car ID.3 body at the assembly line during a press tour at the plant of the German manufacturer Volkswagen AG in Zwickau, Germany.
(ASSOCIATED PRESS)
Those opposed to raising taxes to fund rail expansions have long claimed electric cars will make such investments unnecessary. Experts say boosting transit is not only about greening mobility but limiting energy demand
By Joshua Emerson Smith
California has vowed to ban the sale of new gasoline-powered cars and trucks by 2035, making way for an electric vehicle boom. But researchers and state officials say even that is not enough to meet the state's ambitious climate goals.
People will not only have to embrace cleaner vehicles but trade long car commutes for dense, walkable neighborhoods serviced by transit, experts say. Simply building expensive rail projects, they cautioned, won't help achieve the state's benchmarks unless homes and businesses are tightly packed.
The average person will need to drive no more than about 17 miles a day, down from nearly 25 miles a day in 2019, to meet the state's target of carbon neutrality by 2045, according to the California Air Resources Board. That's partly because nearly a third of personal vehicles in the state are projected to still run on gasoline by then.
"This is a far superior environmental strategy than just promoting electric vehicles, not just because of how these transit-oriented communities can reduce driving miles but also because they spur construction of more compact homes that require less energy to heat and cool and water to irrigate," said Ethan Elkind, director of the climate program at UC Berkeley's Center for Law, Energy and the Environment.
Will San Diego's $160B rail expansion survive GOP election shake-up?
Powerful transportation planning czar pushing for per-mile fees on drivers says he may leave San Diego region if elected officials can't agree on transformative vision for public transit
Californians have long debated the environmental value of public transit, from the state's bullet train to Los Angeles' ongoing subway tunneling to San Diego's envisioned commuter rail expansion. Proponents have repeatedly argued that trains and buses are a crucial part of curbing planet-warming emissions, while opponents have countered that electric vehicles will address such environmental concerns.
When San Diego transportation officials sought approval a year ago for a roughly $160 billion blueprint to expand the region's rail system, for example, local conservatives questioned whether the vision would actually help address climate change.
"The future of transportation is almost certainly going to be autonomous, clean vehicles, and that's already at our doorstep," Coronado Mayor Richard Bailey said during a public hearing on the issue. "This plan largely ignores them."
The debate over the future of transit is, in many ways, a fundamental disagreement about housing. Specifically, should sprawling residential neighborhoods be transformed into densely populated communities akin to San Francisco or West Hollywood?
California is now preparing for a world without gas plants and nuclear power. And the vision, while bold, is also daunting. Electrifying everything from vehicles to home laundry, cooking and heating units will dramatically increase energy demand, all while the state grapples with the full switch to renewable energy.
The state will need to roughly triple annual installation of wind and solar while increasing battery projects eightfold during the next two decades to achieve its climate goals and maintain the grid, according to the California Energy Commission. During the September heatwave, the state set a new record for peak demand at 52,061 megawatts. The agency is preparing for regular spikes up to 78,500 megawatts by midcentury.
Top state officials have drafted and redrafted a blueprint for phasing out fossil fuels, called the Scoping Plan for Achieving Carbon Neutrality. A key strategy of the document is promoting dense, walkable neighborhoods.
"If you don't change development patterns, you end up having more power generation, including delaying retiring existing natural gas plants to accommodate the switch to electric vehicles," said Juan Matute, deputy director of UCLA's Institute of Transportation Studies.
To lower the threat of blackouts, elected leaders from Sacramento to San Diego are pushing developers to build multifamily housing in coastal areas where there's lower demand for power-hungry heating and cooling systems.
Still, cities might want to pause before spending billions of dollars on new rail systems, experts warned. Sprawling L.A. has invested heavily in rail, without significant increases in density, only to see ridership decline.
Electric buses and on-demand shuttles might be a cheaper and better fit for cities struggling to urbanize, said Dan Sperling, a member of the California Air Resources Board and founding director of the UC Davis Institute of Transportation Studies.
"What's happened especially for rail transit, which relies heavily on commuters and more affluent white collar workers, is they've lost much of that ridership," he said. "Transit systems are in dire shape and facing a fiscal cliff in the next few years."
Transit use across the state and country had been declining over the last decade before plummeting during the pandemic. More people have returned to transit in recent months, but work-from-home trends appear to be taking a lasting toll. Nationwide use last year was less than half what it was in 2014 at its peak, according to the American Public Transportation Association.
Pinnacle on the Park apartments look over San Diego's East Village, shown here on Jan.13, 2020.
(K.C. Alfred/The San Diego Union-Tribune)
Now many agencies face the prospect of having to cut service as emergency federal funding runs out, most notably Bay Area Rapid Transit. The San Diego Metropolitan Transit System has said it has enough stimulus cash to last at least through 2027, with ridership down by roughly 40 percent since its high-water mark in 2015.
Given the situation, some elected officials are skeptical about pouring more money into costly transit projects, especially when population growth in the state has flatlined and new home construction continues to struggle.
"I used to joke, you want to be safe from the pandemic, go hang out on a bus or a trolley because there ain't nobody there," said El Cajon Mayor Bill Wells.
Wells was skeptical that many Southern Californians would welcome more urban living, including sharing walls with neighbors and carrying grocery bags down crowded sidewalks.
"Americans don't want to be told what to do," he said. "People are going to resist, even if it's going to cost them more money or if it's not as good for the environment."
TransportationLatestTop StoriesEnvironment
Get Essential San Diego, weekday mornings
Joshua Emerson Smith
Will Southern California embrace logging of its 'sky island' forests?
Flowers, flooding and drought: What recent drenching means for San Diego region
500,000 gallons of raw sewage fouls San Diego Bay after broken sensor shuts down pumps
Democrats retain grip on SANDAG board as Republicans walk out of hearing in protest
Rains flood San Diego shorelines with Tijuana sewage, closing beaches to Coronado
Smart Border Coalition has a new executive director: border native Joaquín Luken
He seeks to work with leaders and organizations on both sides of the border to develop strategies to streamline border crossings.
Amtrak to restore weekend service between San Diego and Orange counties
Slope stabilization work will continue through mid-March, weekday passenger train suspensions continue
Batteries on wheels: General Motors and SDG&E look at EVs to bolster the electric grid
The companies will study how to integrate electric vehicles, chargers and batteries into the power grid
New wrinkle adds to delay for San Clemente railroad repairs and restoring passenger service to and from S.D.
Ground anchor layout may conflict with old foundation piles installed to stabilize homes above recurring landslide
Amtrak riders use 'bus bridge' between Oceanside and Irvine
Railroad segment at San Clemente closed for at least another month as track stabilization work continues
Weather further delays repairs, boosts costs of railroad landslide
Completion of hillside tie-backs at San Clemente pushed to March; costs likely to exceed $12 million
San Diego got 20 trailers to protect homeless people during COVID-19. They've been in storage for years
San Diego to use $2.4 million state grant to help 50 homeless people near old library


Acer AL Series AL drivers are tiny programs that enable your Monitor hardware to communicate with your operating system software. News Blog Facebook Twitter Newsletter.
Furthermore, installing the wrong Acer drivers can make these problems even worse. Monitor Acer AL Series.
Windows XP, Vista, 7, 8, 10 Downloads: This website is using cookies. To achieve a Gold competency level, Solvusoft goes through extensive independent analysis that looks for, amongst other qualities, a high level of software expertise, a successful customer service track record, and top-tier customer value.
As a Gold Certified Independent Software Vendor ISVSolvusoft is able to provide the highest level of customer satisfaction through delivering top-level software and service solutions, which have been subject to a rigourous and continually-audited approval process by Microsoft. How is the Gold Competency Level Attained? You are downloading trial software.


text:
Kuehne + Nagel Group
New Singapore Logistics Hub drives supply chain optimisation for high growth industries
Kuehne + Nagel, one of the leading global logistics providers, today unveiled its Singapore Logistics
Hub, a 50,000 sqm built-to-suit facility located in the west of Singapore. The facility is part of Kuehne + Nagel's regional expansion plan to support its fast growing supply chain clientele operating within Singapore and the ASEAN countries.
Klaus-Michael Kuehne, majority shareholder and Honorary Chairman of Kuehne + Nagel International AG, said, "Singapore is located at the heart of major shipping lanes in Asia. We have identified its pivotal role to regional trade 46 years ago and it remains today an important part of our growth strategy in Asia Pacific. The Singapore Logistics Hub is Kuehne + Nagel's largest investment outside Europe and represents our long-term commitment to the market. The new facility provides the necessary end-to-end, value-added supply chain capabilities to support our customers through Asia's complex trade and logistics landscape."
Centre of Excellence to support high growth industries within Asia Pacific
Located near pharma and healthcare hubs, major manufacturers and ports, the Singapore Logistics Hub provides 46,000 sqm of warehousing space. Aside from the standard freight and warehousing service offerings, the new facility will serve as a regional centre of excellence for high-tech, industrial, pharmaceutical and healthcare customers, offering supply chain optimisation and value-chain transformation solutions.
More than 40 per cent of the new logistics hub has been furnished with advanced chilled storage, redressing and postponement facilities to support the growing base of pharmaceutical and healthcare companies operating in Asia. In combination with Kuehne + Nagel's award winning logistics solution, KN PharmaChain, the Singapore Logistics Hub completes Kuehne + Nagel's regional offering to provide a one-stop end-to-end supply chain solution to the industry.
Driving customer centric supply chain innovation
In line with its global strategy to drive logistics efficiency through supply chain innovation, the Singapore Logistics Hub will include Kuehne + Nagel's first centre of excellence for logistics innovation in the region.
Dr. Detlef Trefzger, Chief Executive Officer of the Kuehne + Nagel Group: "The centre of excellence for logistics innovation is an integral element of Kuehne + Nagel's strategy to foster continual and operations-related logistics innovation through stronger collaboration with customers, partners and employees. Global companies are realising that efficient supply chain management can be the differentiator in today's dynamic business landscape. The centre of excellence will allow us to work alongside our customers and partners in developing technologies and business strategies that are pragmatic and enhance supply chain efficiencies."
In a real life environment a collaborative platform between customers, industry partners, independent and Kuehne + Nagel experts implements and tests applied operations innovations. In this context supply chain efficiencies and working capital improvements are in the focus of the collaborative optimisation activities.
Kuehne + Nagel has invested in building up a robust human resource set-up leveraging on local and regional talents. The new facility will include a Logistics Learning Hub which focuses on driving talent development, training, and succession planning to support business growth.
Over many years Kuehne + Nagel has enjoyed a close and successful cooperation with the Singapore Economic Development Board, especially in the fields of employee education and innovation.
Its Chairman, Dr. Beh Swan Gin, said: "Asia presents many opportunities for companies to create new businesses and further differentiate existing ones. Innovation is therefore critical for the continued transformation of Singapore's logistics industry and the strengthening of Singapore's position as a world-leading logistics hub. We are pleased and honoured to have a long-standing partner, Kuehne + Nagel, travel with us on this exciting journey."
Angela M. Schmidt
angela.schmidt@kuehne-nagel.com
Press Info_New Singapore Logistics Hub drives supply chain optimisation for high growth industries
Kühne + Nagel tritt als Vorreiter der Logistikbranche der Allianz für Entwicklung und Klima bei
Kuehne + Nagel joins the Development and Climate Alliance as a first mover in the logistics industry
Kühne + Nagel expandiert Landverkehrsnetzwerk mit Akquisition in den Niederlanden und Belgien
Kuehne + Nagel acquires in the Netherlands and Belgium to expand its overland network
Kuehne + Nagel results greatly improved
Kühne + Nagel - Ergebnis stark verbessert
Kuehne + Nagel on LinkedIn
© KUEHNE + NAGEL INC All rights reserved
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text:
Q: Design and SEO for a single page dynamic website with AJAX I designed a website in which the whole site is contained within one page (index.php).
Within the page, <section> tags define different parts of the site (home, contact, blog etc.)
Navigation is achieved by buttons that are always visible, and when clicked use javascript to change the visibility of the sections, so that only one is shown at any time.
More specifically, this is done by using the hash in the url, and handling the hashchange event. This results in urls such as www.site.com/#home (the default if no other hash is present) and www.site.com/#contact.
I want to know if this is a good design. It works, but I get the feeling there must be a better way to achieve the same thing? To clarify, I was aiming for site that loaded all the main content once, so that there were no more page loads after the initial load, and moving between sections would be smoother.
On top of this, another problem is introduced concerning SEO. The site shows up in google, but if for example, a search query contains a term in a specific section, it still loads the default #home page when clicked, not the specific section the term was found in. How can I rectify this?
Finally, one of the sections is a blog section, which is the only section that does not load all at once, since by default it loads the latest post from a database. When a user selects a different post from a list (which in itself is loaded using AJAX), AJAX is used to fetch and display the new post, and pushState changes the history. Again, to give each post a unique url that can be referenced externally, the menu changes the url which is handled by javascript, resulting in urls such as www.site.com/?blogPost=2#blog and www.site.com/?blogPost=1#blog.
These posts aren't seen by google at all. Using the Googlebot tool shows that the crawler sees the blog section as always empty, so none of the blog posts are indexed.
What can I change?
(I don't know if this should be on the webmasters stackexchange, so sorry if its in the wrong place)

A: Build a normal site. Give each page a normal URL. Let Google index those URLs. If you don't have pages for Google to index, that it can't index your content.
Progressively enhance the site with JS/Ajax.
When a link is followed (or other action that, without JS, would load a new page is performed) use JavaScript to transform the current page into the target page.
Use pushState to change the URL to the URL that would have been loaded if you were not using JavaScript. (Do this instead of using the fragment identifer (#) hack).
Make sure you listen for history events so you can transform the page back when the back button is clicked.
This results in situations such as:

*

*User arrives at /foo from Google

*/foo contains all the content for the /foo page

*User clicks link to /bar

*JavaScript changes the content of the page to match what the user would have got from going to /bar directly and sets URL to /bar with pushState

Note that there is also the (not recommended) hashbang technique which hacks a one-page site into a form that Google can index, but which is not robust, doesn't work for any other non-JS client and is almost as much work as doing things properly.


We are breeders of quality Sheepadoodle puppies located in North Central Ohio. Look no further. Your search for the right family pet ends here!
A Sheepadoodle is a cross between Old English Sheepdog and Poodle. This highly intelligent cross breed is a loving and friendly family dog. They are easy to train and very loyal. Sheepadoodles shed minimally and are allergy-friendly.
My F1 sheepadoodles are predominately black with white feet/legs, collar, chest, stomach, face, and muzzle, then black markings on head: eyes, ears, etc. The tail is black with a white tip, and tails are left on! The black may go silver/gray with time. My Fb1 sheepadoodles can be similarly black and white, white with a few black spots, or solid white, which usually begins as a creamy white color that brightens with age.
Standard sized Sheepdadoodles weigh anywhere from 50 to 80 pounds and stand between 13 and 24 inches tall.
Is this living teddy bear from Sweet Sheepadoodles the right dog for you and your family? Hear what other families have to say.


text:
Lake Tahoe has seen 138.65 billion gallons of water since October
Ryan Hoffman
rhoffman@tahoedailytribune.com
Third Creek at Lakeshore Boulevard in Incline Village is ripping at the height of the most recent storm run-off on Feb. 9.
Courtesy Steve Dolan
In less than five months, the water level at Lake Tahoe has gone from just below its natural rim to less than three feet of the legal limit.
Put another way, approximately 138.65 billion gallons of water have been added to the lake since Oct. 1, according to the National Weather Service.
And put yet another way, the amount of water since Oct. 1 is enough to supply the average annual household water consumption for 425,506 families.
Buoyed by wet storms in October and November and winter storms in December, January and February that have dumped rain and feet upon feet upon feet of snow in the mountains and at lake level, Tahoe has experienced more precipitation between Oct. 1, 2016, and Feb. 14, 2017, than the same time period in the previous nine years, according to data from the U.S. Geological Survey.
As of 2 p.m. Tuesday, lake level at Tahoe stood at 6,226.22 feet, which is 3.22 feet above the natural rim and 2.88 feet shy of the lake's legal limit (2,229 feet).
Since Oct. 1 Lake Tahoe has risen approximately 3 ½ feet.
Comparatively, lake level has only increased over that time period three times in the past nine years.
The greatest increase, aside from the most recent one, was between 2010 and 2011. Lake level rose 1.05 feet — going from 6,223.47 feet on Oct. 1, 2010, to 6,224.52 feet on Feb. 14, 2011. From 2015 to 2016, the lake rose .2 feet.
Lake level has not been as high on Feb. 14 since 2012, when the lake was 6,226.82 feet.
Beyond the lake, the snow water equivalent in the Lake Tahoe Basin stood at 209 percent of the median, according to the California/Nevada SNOTEL report.
And more wintry — and wet — weather is on the way this week.
"A series of weak to moderate storms is expected to impact the region beginning Thursday and potentially lasting through the middle of next week," according to a special weather statement Wednesday from the National Weather Service in Reno. "The strongest storm in the series will impact the Sierra and western Nevada Sunday night through Monday night."
The potential for strong winds, along with additional rain and snow, will create periods of difficult travel conditions in the Sierra.
"With very wet antecedent conditions in lower elevations and exceptionally deep snowpack at higher elevations, even small amounts of precipitation could create renewed flooding concerns," according to NWS. "The main flooding concerns will continue to be along smaller streams, areas of poor drainage, and main stem rivers in northeast California such as the Pit, Susan and Middle Fork Feather, which have already seen flooding this past week."
While forecasts are still being firmed, up to a foot of snow will be possible during Thursday's storm along the Sierra crest, with only a few inches for areas below 6,500 feet."
Meanwhile, the Sunday night through Monday night system looks to be have an organized cold-frontal structure with better potential to be a heavy snow producer.
"Latest model simulations continue to show impressive ingredients, including a 130+ knot southwest jet stream over the Sierra … moderate atmospheric river, and a strong surface low off the Oregon Coast," officials said. "Snow levels could start above pass level, with a strong cold front eventually pushing them down to at least the western Nevada foothills. Lowering snow levels could reduce the flood threat somewhat, but again we can`t rule out renewed flooding issues."
Snow totals for that next storm are still too early to predict.


This delightful one bedroom ground floor unit has been beautifully renovated throughout. Light bright open plan kitchen and living area tiled throughout. Well appointed kitchen in a modern design, includes electric induction stovetop and near new oven. Provision for dishwasher included in the generous cupboard space. Bathroom and bedroom run off passageway with built-in linen cupboard. Bathroom has been lovingly refurbished has pedestal basin and modern shower recess and toilet. Washing machine is included and located in the kitchen. Carpeted bedroom has new window dressings and a two door melamine robe with drawers. Single carport parking provided to the rear of the unit.
A short walk to the train and with bus transport at the door makes it ideally located for the city worker. Close to shops and all amenities. Complex is in a well maintained block with a pleasant outlook to a park/playing field. Strictly NO pets.