Tony Chater, who has died aged 86, was a mild-spoken but determined Marxist who edited the Morning Star for 21 years, resisting repeated efforts by the Communist Party to oust him for his strict adherence to the Moscow line as the less rigid "Eurocommunism" came into fashion.
A chemistry lecturer, Chater had no experience beyond being the party's head of publicity when in 1974 he took over the Star, renamed from the Daily Worker eight years before. During his editorship its circulation - already tiny - fell relentlessly, but despite round after round of staff cuts and paying minimal salaries he continued to get out a credible paper.
Chater's Star managed some notable scoops. In 1975 it carried Whitehall minutes on how the Heath government's Companies Bill could be tailored to prevent the Queen's private shareholdings being disclosed. Three years later it broke the news of leadership changes at MI5 and MI6 after Downing Street sent it the information by mistake, unaware that the Star operated outside the Whitehall "D Notice" system.
He also printed, during the 1984-85 miners' strike, the name and address of a working Kent miner's wife. When the Mail on Sunday retaliated by printing Chater's address and phone number, he went to the Press Council and won.
The paper was founded as the organ of the CPGB, whose policies were set in lock-step with those of the Kremlin; this usually posed Chater no problems, though he did criticise the Soviet military intervention in Afghanistan. But in the early 1980s the party launched a theoretical journal, Marxism Today, which explored the Eurocommunism with which many in the party were flirting.
During 1983 the party put forward Eurocommunist nominees for the committee of the People's Press Printing Society, the co-operative that ran the paper. In an unprecedented show of independence, they were defeated by hard-line trade unionists.
That November Chater was voted off the party executive, which asked him to resign as editor. He stood his ground, as did David Whitfield (his deputy), Mick Costello (industrial correspondent), the former British Leyland shop steward Derek "Red Robbo" Robinson and Tess Gill of the General and Municipal Workers' Union. When a shareholders' meeting called by the party leadership voted for Chater's removal, the paper ignored it.
In March 1984 the party executive issued a seven-page statement denouncing Chater and calling for its supporters to be elected to control the Star. It said the final straw had been his refusal to print an article submitted on the 60th anniversary of Lenin's death. When shareholders met again after both sides had bought blocks of £1 shares to sway the outcome, the chair ruled a resolution for Chater's dismissal out of order.
A special party conference was called that June to replace Chater with Chris Myant, a Eurocommunist member of his staff. Myant was voted onto the board, but the Moscow-liners kept their 10-2 majority and a resolution to oust Chater was not carried.
In January 1985 the executive, unable to remove them from the paper, voted to expel Chater and Whitfield from the party. Chater denied having put himself at the head of a hard line pro-Soviet faction and accused "revisionists" around Marxism Today of attempting to destroy "the class base and the Marxist-Leninist direction of the party". With 17 others, he was expelled by a 2-1 majority.
The party briefly threatened to start its own daily paper, and made further attempts to take over the co-operative. But as the Kremlin under Mikhail Gorbachev began to champion glasnost and perestroika, the feud lost much of its meaning. The Star came under the sway of the breakaway pro-Kremlin Communist Party of Britain, but while Chater endorsed Gorbachev's approach, the end of the Soviet bloc he had defended was nigh.
Anthony Philip John Chater was born in Northampton on December 21 1929; his parents worked in shoe factories. From Northampton Grammar School he took a First in Chemistry at Queen Mary College, London in 1951 and a PhD three years later.
After spells as a biochemist at Ottawa Experimental Farm and Brussels University, Chater went into teaching, first at Northampton Technical High School, then Blyth Grammar School, Norwich. In 1960 he moved to Luton College of Technology as lecturer, subsequently senior lecturer, in Physical Chemistry, staying until 1969.
Chater fought Luton four times between a by-election in 1963 and the general election of 1970, polling fewer than 600 votes each time. He chaired the Communist Party in 1968-69, then became its head of press and publicity, and a committee member of the Communist-front World Peace Council.
When Edward Heath called the snap "Who governs Britain?" election at the height of the 1974 miners' strike, Chater set his party three objectives: "To defeat the Tories. To secure the return of Communist MPs. And to win a Labour government that can be compelled to carry out Left policies by the mass movement." The outcome was a minority Labour government, with a reinforced left wing.
That June, Chater swapped jobs with George Matthews, the Star's editor for 15 years, declaring: "There will be no change in policy." He proposed to the party's executive a determined campaign for circulation growth; the idea was accepted, but nothing was done.
Instead there was a continued spiral of falling sales and rising cover price, blamed on inadequate leadership by the party's general secretary, Gordon Maclennan, and its executive. Party membership was also falling: from 28,519 to 25,293 between 1975 and 1977.
Chater secured a lifeline when he persuaded Labour ministers to end the embargo on government advertising in the Star - stemming not from its ideology but its lack of audited circulation figures. In 1977 these were finally estimated at 41,235 a day - though the Star would not say how many copies were a bulk order from the Soviet Union - and the advertisements began to appear, and be paid for.
The paper's finances continued to deteriorate, however, and days after Chater printed an editorial demanding a price freeze for the working class it raised its price from 10p to 12p. By 1978 its circulation was down to 36,000, including 15,000 overseas sales.
That year the paper tried to prevent Express Newspapers launching the Daily Star. It received short shrift, the judge who heard the case declaring that "only a moron in a hurry" would confuse the two.
Early in 1981 Chater ran a front-page story that the Morning Star was facing "the most serious crisis in its history" and could be forced to close. He appealed to party members to recruit more readers, and – unsuccessfully – sought party approval to do commercial printing on the Star's presses.
He persuaded the party, as it tried to oust him, to fund a new web-offset press for the Star, with the qualified agreement of the print unions who were still resisting such advances in Fleet Street. In 1988 the paper sold its building in Farringdon Road for £2.1 million to David Sullivan, proprietor of the Daily Sport, and moved to Shoreditch; Sullivan resold it for £3 million.
Anthony Chater married Janice Smith in 1954; they had three sons.


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text:
why are vaquitas endangered
Besides … Gill-nets: The Invisible Killer. ", Report of the Eleventh meeting of the Comité Internacional para la Recuperación de la Vaquita (CIRVA), A combined visual and acoustic estimate of 2008 abundance, and change in abundance since 1997, for the vaquita, Phocoena sinus, A history (1990-2015) of mismanaging the vaquita into extinction - A Mexican NGO's perspective, A new abundance estimate for vaquitas: First step for recovery, A review of acoustic surveys and conservations actions for the vaquita, Assessment of the effect of natural and anthropogenic aquatic noise on vaquita (Phocoena sinus) through a numerical simulation, Conservation of the vaquita Phocoena sinus, Dual extinction: The illegal trade in the endangered totoaba and its impact on the critically endangered vaquita. Vaquitas share waters with the much sought-after totoaba fish and fishing nets inadvertently catch and drown the porpoise. A vaquita is a small, dark grey porpoise that reaches a maximum length of just under five feet and weighs up to 120 pounds. The vaquita is the smallest porpoise, and the smallest cetacean. Once this population of marine mammals goes extinct, the entire species goes extinct. But totoaba fishing—the main threat to vaquitas—has continued to increase. With the recent discovery that the baiji is functionally-extinct, and probably extinct in absolute terms, the vaquita is now recognized as the most-endangered cetacean species in the world. The number of existing vaquitas has always been small since they only live in one area in the entire world. Uncategorized October 23, 2020 0 Comment. Newborns generally have darker coloration. The vaquita, literally "little cow", is a species of porpoise endemic to the northern end of the Gulf of California. Together, we can protect the Gulf of California World Heritage site, home to the critically endangered vaquita. They are dark gray on their dorsal (top) surface with pale gray sides and a white underside with light gray markings. Vaquitas have the smallest range of any whale, dolphin, or porpoise. Mexico has been given one year to demonstrate that it is taking appropriate legal, scientific, technical, administrative and financial measures to protect this heritage site and the animals that live there—including the vaquita. The population trend for this secretive creature strongly suggests time is running out. We used unique sonar scanning technology, provided by Monterey Bay Diving, to find discarded nets likely to entangle vaquitas. (2005). And a 97% drop from the year before that. Once a gillnet was located, we used underwater grappling tools to mark the net, so it could later be removed. We removed an astounding2,000 square metresof net. It is the world's most endangered marine mammal, and one of the most endangered creatures on earth. The Upper Gulf of California is considered globally unique because of its ecological characteristics, enormous biodiversity and the amount of species that live in this area. why is the vaquita endangered. Gerrodette, Tim ; Taylor, Barbara L. ; Swift, René ; Rankin, Shannon ; Jaramillo-Legorreta, Armando M. ; Rojas-Bracho, Lorenzo (2010). Some vaquitas have individually … View our inclusive approach to conservation. NATURAL HISTORY. The vaquita is found only in a small area of the world. The original population in the 1930s was estimated to be around 5,000 individuals strong. It also has a black line around its lips, which gives the appearance of a smile. Make a donation to help save some of the world's most endangered animals from extinction and support WWF's conservation efforts. An all time low for the porpoise, the population is half of what it was just the year before. In it God gives us all the gift of personal time with him. They live to be about 20-21 years old. WWF is asking for an immediate, increased response from the Mexican government, World Heritage Committee and CITES Parties, NGOS and civil society groups to protect the last remaining vaquitas and set the Upper Gulf of California on a path to recovery. The swim bladders are often illegally smuggled over the US border and then shipped to China where it can sell up to USD 8,500 per kilogram in the black market. As the vaquita porpoise heads towards extinction, new management measures in Mexico still may have missed the point -- affecting not one but two critically endangered marine species. The Vaquita (Phocoena Sinus), also known as the "Gulf of California Harbor Porpoise" and "Cochito", is the smallest, rarest and most endangered of all cetaceans. Vaquitas only live in the northern end of Mexico's Gulf of California. It has been listed as critically endangered since 1996. Today, the species is on the brink of extinction. It is one of the rarest and most-endangered species of marine mammal in the world. But, we must ask the Mexican president to take strong action now. Sporting a stocky, porpoise shape, the species has distinguishable dark rings which surround their eyes, along with dark patches on their lips and a dark line running from their mouths to their dorsal fins. Photo obtained under permit No. Gillnets hang in the water like a wall catching everything and everyone that passes. The Vaquita was first discovered by western scientists in 1958. There may be fewer than 30 vaquita left in the world and we can save them. The Gulf of California World Heritage site is at risk of being listed as in danger by the World Heritage Committee. WHY DOES BAD STUFF HAPPEN? 2. WHY SATURDAY? It lives only in the Gulf of California (Sea of Cortez), where latest abundance estimates point to just 30 animals left (as of November 2016). I'll tell you here, that the vaquita is species of porpoise (a marine mammal related to whales and dolphins) found only in the Northern Gulf of California in Mexico – it is the most endangered marine mammal on the planet, and has likely been in decline since the 1940s. The porpoise has a conspicuous black ring around each eye. 1250 24th Street, N.W. On June 30, 2017, the government of Mexico announced a permanent ban on the use of gillnets in the Upper Gulf of California. This little porpoise was only discovered in 1958, yet it's already on the brink of extinction. The survival of the species is threatened mostly because of the reduction of the flow of water in Colorado River. info /at/ porpoise.org. Failure to act will result in the imminent extinction of the vaquita. Demand for totoaba swim bladders – believed to cure a variety of illness and diseases in Chinese medicine- is driving the vaquita to extinction. What do vaquitas look like?The world's smallest porpoise, vaquitas measure up to five-feet long and weigh up to 120 lbs. Averaging 150 cm or 140 cm in length, it is the smallest of all living cetaceans. The vaquita becomes tangled in the nets used to catch totoaba, which are a delicacy in China. Cantú-Guzmán, Juan Carlos ; Olivera-Bonilla, Alejandro ; Sánchez-Saldaña, María Elena (2015). With less than 30 animals left in the wild, the vaquita needs all the support it can get. Vaquita are often caught and drowned in gillnets used by illegal fishing operations in marine protected areas within Mexico's Gulf of California. The scientific name Phocoena is from the Latin word "porpoise" or "pig fish."Sinus means "cavity," a reference to the Gulf of California. Take action and ask Mexican President Peña Nieto to enforce protection of the vaquita. They only live in the northern part of the Gulf of California, an area that is rich in fish and shrimp. WWF is urgently working to ensure they can live and thrive in their natural habitat. Washington, DC 20037. 05. Recent research estimates the population at fewer than 10 individuals. The world's population of vaquitas, a small porpoise that lives in the Upper Gulf of California, consists of only 12 individuals (and possibly fewer). Why are vaquitas in such trouble? Updated on: March 7, 2019 / 6:19 AM / AP Final effort to save the rarest marine mammal . The primary threat to vaquitas is entanglement in fishing gear. The vaquita is the world's rarest marine mammal—and is in dire need of our help. A baby Vaquita. Newborns are born in the spring (March/April). World Wildlife Fund Inc. is a nonprofit, tax-exempt charitable organization (tax ID number 52-1693387) under Section 501(c)(3) of the Internal Revenue Code. Currently, there are so few individuals left, that they are considered to be the most endangered cetacean species in the world. "Monterey Bay Diving is proud to be a part of this project and maintains a strong advocacy … With as few as around 10 left, the species will become extinct without a fully enforced gillnet ban throughout their entire habitat. Vaquitas feed on small fish, crustaceans (such as shrimp), and cephalopods (such as squid and octopuses). Learn more about the vaquita and what you can do to save them. But in recent years, the population has declined at a dramati… The vaquita is the most endangered cetacean in the world. "If there are only so few left, can we still save the vaquita? Join us to make change. The vaquita lives only about a 4 hour drive from San Diego. Why is the Vaquita so endangered? Fishing is thus a major source of income for the people there, who almost exclusively use gillnets, but vaquitas can also become accidentally wrapped in the nets and drown. The Vaquita has been classified as one of the top 100 evolutionary distinct and globally endangered (EDGE) mammals in the world, but has also taken on the ominous distinction of the most endangered cetacean (aquatic mammals that include porpoises, whales and dolphins) in the world.. The Vaquita is the smallest and most endangered cetacean species along with being one of the most endangered species on the planet. For years, gillnets set to catch shrimp decimated the vaquita population. The vaquita in the Gulf of California is the most endangered cetacean in the world. Based on abundance estimated in 2008, there are estimated to be less than 100 vaquitas remaining. 3. The Vaquita. Why is the Vaquita endangered? Speak up for species and places through WWF's Action Center. 4. Vaquita: the most endangered marine mammal In May and October of 2017 we joined forces with the International Committee for the Recovery of the Vaquita (CIRVA), and Monterey Bay Diving to locate and remove illegal gillnets from the critical vaquita porpoise habitat in the Gulf of California. The main threat to vaquitas is death by drowning in fishing gear. Donate – Many organizations are collecting funds to help aid conservation. The steep decline in abundance is primarily due to bycatch in gillnets from the illegal totoaba fishery. Cetaceans include whales, dolphins and porpoises. 5. The vaquita is the world's smallest and most endangered porpoise and it is literally on its last fins. DR7488708 of SEMARNAT (Mexican National Commission of Protected Natural Areas). Its population has been declining 15% each year since the 1940's, decreasing by more than 50% in the last three years. But its natural predator, the shark, is not its biggest threat. How many vaquitas are left?A survey released earlier this year estimated the vaquita population was as low as 30 individuals. Vaquita is most endangered species of all the marine species. LORENZO ROJAS-BRACHO ; RANDALL R. REEVES ; ARMANDO JARAMILLO-LEGORRETA (2006).
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2020 why are vaquitas endangered

redpajama_set_name: RedPajamaCommonCrawl


Following is a write-up on gel nail polish pink.
You would better clean both hands and apply some hand cream before starting the job. When you do this, there is every risk that this kind of product is going to be damaged by all potential ways. By having patience, and observing the actions listed previously should finally have a simple comprehension of the best way to do your very own French nails in the home.
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Let just start out saying this is the second time I've made this recipe, and liked it way better the first time through. I think I know why; there are a couple of differences. The first go-around, I tied together two pork loins, cut from a full loin bought at Costco. Also, I used dried sage, not fresh. Okay, so those are the main differences. The wider thickness of the two loins tied together allowed a longer roast, so it didn't dry out. Also, the fresh sage is so incredibly strong that it gave the second roast a soapy taste. Not pleasant! I tell a lie; there's a third difference. The first time, I used thin slices of pancetta, not smoky bacon. With the bacon, the roast was constantly bathed in bacon fat, so it kind of stewed in a pool of juicy fat, which I ended up draining off.
Enough with all that. How do you like my new brining vessel? It worked perfectly, and I'll use it again for pork roasts and cut-up chickens. The fish poacher has sat in its original box, on a shelf in a storage bin in the garage, for the last twelve years. I'm so glad it wasn't donated to the thrift shop. It fits nicely on the fridge shelf too, not too bulky.
Here's the recipe from Epicurious, with my parenthetical changes/comments.


text:
Q: Consume events from EventHub In Azure Databricks using pySpark I could see spark connectors & guidelines  for consuming events from Event Hub using Scala in Azure Databricks.
But, How can we consume events in event Hub from azure databricks using pySpark?
any suggestions/documentation details would help. thanks

A: Below is the snippet for reading events from event hub from pyspark on azure data-bricks.
// With an entity path
val with = "Endpoint=sb://SAMPLE;SharedAccessKeyName=KEY_NAME;SharedAccessKey=KEY;EntityPath=EVENTHUB_NAME"

# Source with default settings
connectionString = "Valid EventHubs connection string."
ehConf = {
  'eventhubs.connectionString' : connectionString
}

df = spark \
  .readStream \
  .format("eventhubs") \
  .options(**ehConf) \
  .load()

readInStreamBody = df.withColumn("body", df["body"].cast("string"))
display(readInStreamBody)

A: I think there is slight modification that is required if you are using spark version 2.4.5 or greater and version of the Azure event Hub Connector 2.3.15 or above
For 2.3.15 version and above, the configuration dictionary requires that connection string be encrypted, So you need to pass it as shown in the code snippet below.
connectionString = "Endpoint=sb://SAMPLE;SharedAccessKeyName=KEY_NAME;SharedAccessKey=KEY;EntityPath=EVENTHUB_NAME"
ehConf = {}
ehConf['eventhubs.connectionString'] = sc._jvm.org.apache.spark.eventhubs.EventHubsUtils.encrypt(connectionString)

df = spark \
  .readStream \
  .format("eventhubs") \
  .options(**ehConf) \
  .load()

readInStreamBody = df.withColumn("body", df["body"].cast("string"))
display(readInStreamBody)

redpajama_set_name: RedPajamaStackExchange


text:
Nootropic Supplements: An Elevated State Of Mind
Drew "Vanilla Gorilla" Peters Jun 22, 2018 Supplement Knowledge Leave a Comment
Introduction: What Are Nootropics?
One of the fastest growing categories of supplements in the market today, both sports nutrition and general use is that of nootropics. 'Brain boosters', if you will, nootropics is an umbrella term used to classify a wide category of chemicals, both natural and synthetic, that provide positive cognitive benefits to the human brain. The term was coined by a Roman psychologist, Dr. Corneliu E. Guirgea, who is considered the father of nootropics and godfather of brain pharmacology. The word nootropics originates from the Greek word noos (mind) and tropein (towards) (1).
His formal description of the category states that "Nootropics are drugs which ameliorate the functional "plasticity" of the central nervous system. The nootropic drug acts at the telencephalic level through a series of bioenergetic, hemorheological, microcirculatory and neurochemical mechanisms. As to this, recent data show a facilitation by piracetam, of the efficiency of the central cholinergic system." (2) He is most famous for being the first to synthesize what is considered the first man-made nootropic, Piracetam in 1964 (3). To summarize Dr. Guirgea's definition of what classifies a substance as a nootropic, it must meet the following criteria:
Possess little to no side-effects and be non-toxic
Protect the brain from chemical and physical assaults
Increase the efficacy and efficiency of neuronal firing control mechanisms
Enhance memory and the ability to learn
Help the brain function under disruptive conditions
While the above list is a pretty stringent classification standard for any substance, the term nootropic has been used more loosely in today's world, often describing any substance that offers a cognitive benefit. These more loosely defined substances are ones that do such things as improve concentration, increase processing speed and improve memory.
Legality: Who Regulates Nootropics?
As you can imagine, both natural and synthetic nootropics have gained popularity and for good reason. There are some that are perfectly fine for over the counter sale and use, while some aren't allowed to be sold as dietary supplements. This is often considered a gray area as there is no single governing body that holds an identical definition of what a constitutes an approved nootropic. A vast majority of governing bodies consider nootropics dietary supplements.
The fine line comes when they are synthetically produced at which point you must consider: Is the nootropic controlled which requires a prescription or age restriction for purchase, or is it scheduled which means it is ranked by its risk for abuse. Like most drugs, the schedule of a drug influences the control very closely: The higher the risk, the more control there is over the substance.
With this article, we will examine herbal extract, dietary supplement nootropics, and synthetic/semi-synthetic nootropics and see what the research says.
Synthetic Nootropics
When we are referring to synthetic nootropics, we are talking about a category known as racetams which is a category of nootropic that works by prevents the degradation and increases production of the neurotransmitter acetylcholine. Some racetams work to improve the functionality of acetylcholine receptors while other variations adjust the production to scale up or lastly can prevent the breakdown of acetylcholine. This is important as acetylcholine is vital for everything including decision making, focus, memory, and other cognitive based effects (4). Unfortunately, many of these are considered to be drugs and therefore cannot be purchased OTC or as supplements. However, in some markets they can be purchased as research chemicals.
Regarded as the first nootropic drug to be invented by Dr. Guirgea, Piracetam continues to be a very popular choice for those that utilize nootropics and is often viewed as a 'beginner' nootropic for those new to experimenting with such a drug. Also known as Nootropyl or UCB6215, it works via stimulation of acetylcholine receptors, increasing their production. Research has also revealed that it increases glucose and oxygen consumption in the brain which precedes cognitive improvement (4).
One of the most thoroughly studied racetams, Piracetam has been shown that in young and otherwise healthy adults to provide cognitive enhancement, though the benefits are greater and more pronounced in populations which may have cognitive impairment such as aging (5). Also promising is that research seems indicative that Piracetam can help improve cognitive function in those with degenerative cognitive function (6). As a whole, with the real-world trials and research available, Piracetam is considered to generally be more of a preventative mechanism for reducing cognitive aging vs. a short-term agent for improving immediate cognitive enhancement. The recommended daily dosage is 800mg, three times a day. The half-life is approximately 5 hours following oral on intravenous administration with the half-life in cerebrospinal fluid lasting around 8.5 hours (7).
Synthesized from the parent nootropic Piracetam, this compound has modifications within the similar structure. First synthesized in 1984, the primary purpose would be best suited for anti-amnesiac properties. There isn't a large body of evidence available for its efficacy, especially in humans, however, the potential reported benefits include improved cognitive ability for those with brain trauma and improvement in memory formation in elderly populations (8). The ideal scenario for dosing is 400mg three times a day or 600mg twice a day.
Perhaps the most closely related member of the racetam family to Piracetam, Phenylpiracetam is Piracetam with an additional phenyl group added to its structure. Also known as Phenotropil and Carphedon, this synthetic nootropic is rapidly and well absorbed via its enhanced lipophilicity. Compared to the parent drug Piracetam, it has an enhanced anti-amnesiac and neuroprotective effect (9).
Like something out of the 1980's Rocky IV movie, there is a relatively large body of research on Phenylpiracetam in Russia, but unfortunately most of it isn't published online for use outside of the country. From these studies, it is said that there is strong evidence for attenuating and treating cognitive decline. Aside from the neuroprotective effects, there is published data for Phenylpiracetam having an apparent anti-depression mechanism as well as psychostimulatory properties that inhibit sleep (10) (11). General dosing guidelines suggest that 100mg a day are adequate as it is relatively conservative in the dosing needed. Users can increase usage with experience.
A fat-soluble nootropic that needs to be ingested with fatty acids, Aniracetam is a cholergenic compound. Yet another stemming from Piracetam, it is the Piracetam molecule with an amine replaced with a methylated phenyl group. Its mechanism of action is that of a positive modulator of AMPA receptors (12). It has a prolonged, yet controlled effect of neurological stimulation and can decrease the rate of receptor desensitization. It is considered to be 5 times stronger than the parent Piracetam, however it takes significantly longer to break down completely in the body with the tradeoff of being longer lasting in effect.
There appears to be a neuroprotective effect from Aniracetam as research has shown it can help alleviate memory and learning impairment caused by damage such as blunt trauma and cerebral ischemia (13). Regarding learning in general, there has also been a specific effect in receptor desensitization, translating to potential benefit in memory formation (14). There is also a notable increase in judgment due to a significant increase in dopamine and serotonin which also doubles as an anti-depressant (15). Typical recommended dosage is 750mg up to three times a day. It has a short half-life of around 2 hours so it is ideally consumed on an evenly spaced basis (16).
Last but not least, stemming also from Piracetam is Oxiracetam. It is structurally similar to Piracetam featuring the same structure with the inclusion of a single hydroxyl group (17). Oxiracetam is known as a GABA analog that supports phospholipid metabolism as well as influencing a positive modulation of AMPA receptors and helps influence neurotransmitter release, very similar but markedly more potently than its parent compound Piracetam (18).
Oxiracetam is similar to the effect of Aniracetam in that it appears to increase long-term potentiation of acetylcholine release while not modifying the resting acetylcholine concentrations in the brain (19) (20). When it comes to memory formation, the data is positive but considered unreliable, however, it has a more pronounced effect in regard to having anti-amnesiac properties (21) (22). Psychostimulatory properties have been noted with Oxiracetam use, however to a small degree and there is no negative impact on sleep quality, though it can increase the time required to fall asleep (23).
In summation, there is an apparent implication for increasing memory in otherwise healthy subjects, though it appears there is a 5-day loading period required for maximum efficacy (24). Perhaps the wisest range of recommended dosing, the range can go from 700mg a day all the way to 2,400mg, taken at 6-hour intervals. It is best dosed approximately an hour before desired effects. The half-life is approximately 8 hours in healthy individuals with a huge range of 10-68 hours in individuals with renal dysfunction (25).
Which Synthetic Nootropic is Best?
There are potential benefits to each of the racetams listed above. Each is good in its own respect, so the best approach is to evaluate what you are trying to achieve and use trial an error with the given dosage guidelines to see what works for you. As with any substance, everyone has a unique biochemistry, so there is no cookie-cutter approach for which is 'best'.
Dietary Supplement/Herbal Nootropics
Now that we've covered the various synthetic versions of nootropics, let's examine the more natural side of things that are available over the counter for use as a dietary supplement. As with the synthetic nootropics we just discussed, you should select natural nootropics based on what you are trying to achieve, and the best method is to try them out and see what works best for your individual biochemistry. With that being said, let's examine some of the most popular 'nootropic' supplements:
A compound found naturally in plants such as Club Moss, Huperzine A is a very common nootropic. Commonly altered to create the nootropic form, it has been regarded as a premier cognitive enhancer due to the high purity of the substance it produces. It is known for its action as an acetylcholinesterase inhibitor (26). It also has properties for neuroprotection and can block NMDA receptor without the negative side effects of other such compounds (27). In a simple summary of effects, it inhibits enzymes that degrade neurotransmitters and is being researched as a potential compound for reducing cognitive decline in elderly populations. Standard dosing is 50-200mcg per day and has a half-life of 10-14 hours (28).
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Bacopa leaf extract, also commonly listed as Bacopa monnieri is a creeping marsh plant and regarded as an Ayurvedic herb that has been used primarily for neurological regeneration, memory enhancement and anxiety (29). It has also been used in traditional medicine for depression, learning, various neuropharmacological disorders (30). Bacopa monnieri also possesses properties of anti-inflammatory, antipyretic and acts as an astringent (31). There appear to be up to 14 compounds found within this extract with them being generally referred to simply as Bacoside A & B at up to 8% of the dry leaf content (32).
Bacopa monnieri has a variety of promising applications supported in literature, and one of the main mechanisms of action being the interaction with dopamine and serotonergic systems and neuron communication via the increased growth of dendrites (33). Supplementation has shown to improve overall mental cognition in subjects by way of reduced anxiety and is often used for nootropic purposes (34). In regard to dosage, the standard dosage in literature is 300mg with an assumed bacoside content of 55% or higher and it should be consumed with a lipoid transporter as it is fat soluble (35).
A naturally occurring cholinergic compound alpha-glycerphosphocholine, known as Alpha-GPC for short. Classified as a choline-containing phospholipid and an intermediate of lecithin metabolism or simply a lecithin molecule with two less fatty acids, it's a choline pro-drug, and is known to be a precursor to acetylcholine and phosphatidylcholine in the body following ingestion (36). Alpha-GPC is as a naturally occurring constituent of red meat and organ tissue for dietary sources, but for the most part is scarce in appreciable amounts in naturally occurring sources (37). Supplemental Alpha-GPC is typically made synthetically through enzymatic creation via egg or soy lecithin (38).
Alpha-GPC has been shown in research studies to have a variety of positive effects. Brain detoxification is one potential benefit as various studies have supported this with improvement in cognitive deficits (39), decreases in mental fatigue and reduction in metabolic stress of exercise (40). Alpha-GPC has also been shown to support healthy brain aging as various studies have supported findings that deterioration was less in groups supplemented with Alpha-GPC (41), therapeutic benefits in recovery from stroke (42), and significant improvements in most neuropsychological parameters tested (43). Lastly from a performance perspective, Alpha-GPC has the potential to increase growth hormone output, however there is currently only a single study so this area of research interest is considered ongoing (44). Recommended dosage is 600mg at bare minimum with the research supporting cognitive benefits coming at 1200mg.
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Choline Bitartrate is the salt form of choline with bitartrate being added to stabilize and help with absorption and contains approximately 41% choline by molecular weight (45). Choline is a direct precursor of the neurotransmitter acetylcholine and plays a vital role in the body with aiding in nerve signaling, cell membrane maintenance, triglyceride transportation from the liver as the primary sports nutrition purpose of a neurotransmitter vital to nerve and muscle function and normal liver metabolism (46). Though there is no conclusive evidence for supplementation of choline bitartrate as research is still being conducted, there has been a wide array of potential benefits hypothesized from supplementation, stemming from having additional choline available to act as a neurotransmitter.
Known formally as Yamabushitake, Lion's Mane is a dietary mushroom that has recently emerged as a nootropic supplement. This particular mushroom grows in Japan and China from old or dead broadleaf trees. Ingestion of Lion's Mane appears to increase nerve growth factor (NGF) levels and secretion (47). An analogue contained within, 3-hydroxyhericenone, has been shown to prevent neuron death induced by stress and to enhance myelination of neurons as well (48). One specific study using 98% pure Lions Mane powder showed significant improvements on a rating scale in individuals with dementia and cognitive decline by increasing cognition relative to control (49). Additionally, there has been noted decreases in anxiety and depressive symptoms with supplementation (50). Based on research, the 'optimal' dosage of Lion's Mane isn't known, however the studies referenced for cognitive improvements used 1,000mg taken three times per day.
A fat-soluble amino acid, phosphatidylserine is a naturally occurring phospholipid that exists in all species, and comprises a portion of the phospholipid pool. Specifically, it is particularly concentrated in the human brain (15%), lungs (7.4%), testes (6.4%), kidneys (5.7%), liver (3.8%), skeletal muscle (3.3%), heart (3.2%) and blood plasma (0.2%) (51). Phosphatidylserine can be found in soy lecithin, bovine brain, Atlantic mackerel, chicken heart, Atlantic herring and in smaller amounts in chicken leg and liver (52). The first supplemental form of phosphatidylserine was from the bovine cortex, and while this form appears to be superior in the effects of proposed cortisol reduction compared to soy-based supplementation, the source from bovine brain is no longer used due to concerns over Creutzfeldt–Jakob disease (53).
Phosphatidylserine has been shown in research to possess a variety of positive benefits when supplemented. One of the primary positive benefits of phosphatidylserine supplementation is improved mental cognition as well as prevention of cognitive decline with such supporting studies specifically finding that supplementation has been shown to significantly reduce symptoms of Alzheimer's disease and dementia. These studies also supported a positive increase in global glucose utilization in the brain of up to 14.8% (54). There has also been a documented decrease in exercise-induced cortisol with phosphatidylserine supplementation, though the efficacy of the form derived from soy doesn't appear to have the same supporting data as the bovine source (55). Dosage is a standard 100mg divided in 3 total doses for the day for preventing cognitive decline.
N-Acetyl Tyrosine is a modified version of the amino acid L-tyrosine. It has the active compound acetic acid added to enhance the bioavailability and absorption as a whole and in theory, increase the supporting functions of tyrosine within the body (56). Tyrosine is an amino acid that is used to produce the catecholamines noradrenaline through the catecholamine pathway. Tyrosine undergoes a series of conversions with the rate-limiting step in the overall process being the enzyme tyrosine hydroxylase (57). Supplementation with tyrosine appears to have anti-stress mechanisms for acute stressors and may also preserve stress-induced memory deficits (58).
Research has shown tyrosine supplementation to effectively improve cognition as well as cause a reduction in blood pressure during acute stress situations (59) (60). There are also marked increases in subjective well-being and improvements in working memory, though the data is inconclusive and research is ongoing for the latter (59) (61).
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L-Theanine, known by the technical name r-glutamylethylamide is a nondietary amino acid derived primarily from the natural source of Camellia sinesis. The theanine content of these leaves is approximately 0.9-3.1% of the dry weight of the leaves and said to range from 25-60mg per 200mL serving of tea (2.5g of dried tea leaves) (62). It is structurally similar to glutamine and is known as a relaxation agent without sedation with the proposed mechanism being a reduced perception of stress and slight improvements in attention (63).
Regarded as a relaxation agent without sedation and appears to act via blocking the effects of glutamate in the brain as well as stimulating the production of the inhibitory, relaxing neurotransmitter GABA (64). There is also a marked increase in alpha waves in the frontal and occipital lobes of the brain (65) and has research support in reducing stress perception and improvements in attention (66). Interestingly, there also appears to be a protective measure from theanine supplementation when taken before stressful situations in preventing the elevation of stress hormones and oxidative damage (67). Also of interest is that theanine has been shown in studies to significantly improve nitric oxide production in endothelial cells (68). L-theanine is generally taken in the dosage of 100-200mg per day and is commonly paired with caffeine.
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As you can see, there are quite a few 'natural' nootropics on the market that have benefits aside from just cognitive enhancement. If you are looking for a cognitive advantage without negative sides you have plenty to pick from and the cool part is there are some other positive effects that can come with their use. On the natural side, this makes it especially true that if you are looking to try a nootropic, don't just look at the cognitive side, but the other potential benefits.
Suppz Recommended Nootropic Supplements
At Suppz we carry a great selection of Nootropics. We have focus nootropic blends as well as sleep & anxiety nootropics and basic nootropic compounds. Our top recommended products are listed below.
SNS Focus XT
MyoBlox Skywalk
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Anastasis LAX
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(S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats. Li, Wan.10052, August 2017, Sci Rep, Vol. 7.
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The NMDA receptor ion channel: a site for binding of huperzine A. Gordon, R.S1, 2001, Journal of Applied Toxicology, Vol. 21, pp. S47-S51.
Pharmacokinetics of huperzine A following oral administration to human volunteers. Li, Y.Oct-Dec 2007, Eur J Drug Metab Pharmacokinet, Vols. 32-4, pp. 183-7.
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Bacopa monnieri modulates endogenous cytoplasmic and mitochondrial oxidative markers in prepubertal mice brain. Shinomol, G.4, February 2011, Phytomedicine, Vol. 18, pp. 317-26.
Antistress effects of bacosides of Bacopa monnieri: modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Chowdhuri, D.7, November 2002, Phytotherapy Research, Vol. 16, pp. 639-45.
Bacosterol glycoside, a new 13,14-seco-steroid glycoside from Bacopa monnier. Bhandari, P.2, 2006, Chem Pharm BUll, Vol. 54, pp. 240-1.
Enhancement of basolateral amygdaloid neuronal dendritic arborization following Bacopa monniera extract treatment in adult rats. Vollalla, V.4, Sao Paulo : s.n., April 2011, Clinics, Vol. 66, pp. 663-71.
Chronic effects of Brahmi (Bacopa monnieri) on human memory. Roodenry, S.2, August 2002, Neuropsychopharmacology, Vol. 27, pp. 279-81.
Neuropharmacological Review of the Nootropic Herb Bacopa monnieri. Aguiar, S.4, August 2013, Rejuvination Res, Vol. 16, pp. 313-26.
Revisiting choline alphoscerate profile: a new, perspective, role in dementia? Scapicchio, P.7, July 2013, INt J Neurosci, Vol. 123, pp. 444-9.
Purification of L-alpha glycerylphosphorylcholine by column chromatography. Zhang, K.January 13, 2012, J Chromatogr A, Vol. 1220, pp. 108-14.
Simplified preparation of L-alpha-glyceryl phosphoryl choline. Brockerhoff, H.10, October 1965, Can J Biochem, Vol. 43, p. 1777.
Acetyl-L-carnitine improves cognitive functions in severe hepatic encephalopathy: a randomized and controlled clinical trial. Malaguarnera, M.4, December 2011, Metab Brain Dis, Vol. 26, pp. 281-9.
Oral acetyl-L-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study. Malaguarnera, M.4, Aprill 2011, American Journal of , Vol. 93, pp. 799-808.
Efficacy and tolerability of choline alphoscerate (cereton) in patients with Parkinson's disease with cognitive disorders. Levin, O.11, 2009, Zh Nevrol Psikhiatr Im S S Korsakova, Vol. 109, pp. 42-6.
alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic attacks. An Italian multicenter clinical trial. Barbagallo, S.June 30, 1994, Ann N Y Acad Sci, Vol. 717, pp. 253-69.
Multicentre study of l-alpha-glyceryl-phosphorylcholine vs ST200 among patients with probable senile dementia of Alzheimer's type. Parnetti, L.2, Mar-Apr 1993, Drugs Aging, Vol. 3, pp. 159-64.
Acute supplementation with alpha-glycerylphosphorylcholine augments growth hormone response to, and peak force production during, resistance exercise. Ziegenfuss, T.Suppl 1, September 2008, Journal of the International Society of Sports Nutrition, Vol. 5.
Choline supplementation and measures of choline and betaine status: a randomised, controlled trial in postmenopausal women. Wallace, J.7, October 2012, British Journal of Nutrition, Vol. 108, pp. 1264-1271.
Effects of choline on health across the life course: a systematic review. Leemakers, ET and Moreira, EM.8, August 2015, Journal of Nutrition Review, Vol. 73, pp. 500-522.
Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Mori, K.9, September 2008, Biol Pharm Bull, Vol. 31, pp. 1727-32.
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Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Nagano, M.4, August 2010, Biomed Res, Vol. 31, pp. 231-7.
Brain cephalin, a mixture of phosphatides, separation from it of physphatidylserine, phosphatidylethanolamine and a fraction containing an inositol phophatide. August 1942, pp. 34-44.
Phospholipids and sports performance. Jager, R. 5, July 2007, Journal of the International Society of Sports Nutrition, Vol. 4.
Pharmacological effects of phosphatidylserine enzymatically synthesized from soybean lecithin on brain functions in rodents. Sakai, M. 1, Tokyo : s.n., February 1996, J Nutr Sci Vitaminol, Vol. 42, pp. 47-54.
Effect of Phosphatidylserine on Cerebral Glucose Metabolism in Alzheimer's Disease. Klinkhammer, P. 4, 1990, Dementia and Geriatric Cognitive Disorders, Vol. 1.
Blunting by chronic phosphatidylserine administration of the stress-induced activation of the hypothalamo-pituitary-adrenal axis in healthy men. Monteleone, P. 4, 1992, Eur J Clin Pharmacol, Vol. 42, pp. 385-8.
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text:
New drug being trialled for aggressive brain cancer
Professor Shudong Wang
A new drug candidate has been discovered by the University of South Australia (UniSA) to treat the most lethal form of brain cancer – glioblastoma – which kills 95 per cent of patients within five years.
Initial data of the experimental drug, Auceliciclib, in animal models suggest it could offer a new treatment for glioblastoma as there is currently no cure.
Head of Drug Discovery and Development at UniSA, Professor Shudong Wang, says that brain cancer is particularly challenging to treat because very few drugs can cross the blood-brain barrier and those that do cause serious side effects.
"We already know that many cancers are driven by a family of enzymes called cyclin-dependent kinases (CDKs), so our drug has been specifically designed to target CDK activity," Prof Wang says.
"Auceliciclib has two key advantages over other drugs in development. It is more target-specific and therefore appears to have lower toxicity, and it can reach cancer cells in the brain more effectively."
Human clinical trials of the drug in cancer patients will be conducted by industry partner, Aucentra Therapeutics, an Adelaide-based biotech company, initially in Adelaide followed by other clinical trial centres in Australia.
"This will be the first clinical trial in the world of this drug, and I am very excited that a cancer therapeutic discovered at UniSA will be tested firstly in Adelaide for the benefit of South Australian cancer patients," Prof Wang says.
Although glioblastoma is rare and affects only three in 100,000 adults per year, most people survive only 12-15 months after diagnosis with current standard care.
Prof Shudong says the blood-brain-barrier is difficult to penetrate because it does a superb job of protecting the body's most vital organ from infection.
"This is why it is such a challenge to design drugs for brain cancer."
Glioblastoma cells
If Auceliciclib proves effective in human clinical trials, it will also be an important breakthrough for other breast and lung cancers which metastasize into the brain, leaving few other treatment options.
"Given that Auceliciclib targets CDK enzymes that play central role in most human tumours, the application for Auceliciclib could also be much wider and include breast cancer, colorectal cancer, lung cancer, ovarian cancer and leukaemia," Prof Wang says.
Notes for editors
Professor Shudong Wang is a world-renowned leader in kinase-targeted cancer drug therapies. In 2017 she was honoured with the NHMRC Research Excellent Award by the National Health and Medical Research Council for her Top Ranked Development Grant in Australia.
Professor Wang's team collaborates with researchers globally, funding organisations, donors, and pharmaceutical companies in a common goal to find a cure for cancer.
Media contact: Candy Gibson office +61 8 8302 0961 mobile: +61 434 605 142
email: candy.gibson@unisa.edu.au
Lead researcher: Professor Shudong Wang office: 8302 2372 mobile: 0400 266 639
email: shudong.wang@unisa.edu.au


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redpajama_set_name: RedPajamaGithub


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Pot Legalization Has Gained Rapid Favor
by your humble narrator | Jul 6, 2013 | Marijuana News | 0 comments
It took 50 years for American attitudes about marijuana to zigzag from the paranoia of "Reefer Madness" to the excesses of Woodstock back to the hard line of "Just Say No."
The next 25 years took the nation from Bill Clinton, who famously "didn't inhale," to Barack Obama, who most emphatically did.
Now, in just a few short years, public opinion has moved so dramatically toward general acceptance that even those who champion legalization are surprised at how quickly attitudes are changing and states are moving to approve the drug — for medical use and just for fun.
It is a moment in America that is rife with contradictions:
People are looking more kindly on marijuana even as science reveals more about the drug's potential dangers, particularly for young people.
States are giving the green light to the drug in direct defiance of a federal prohibition on its use.
Exploration of the potential medical benefi t is limited by high federal hurdles to research.
Washington policymakers seem reluctant to deal with any of it.
Richard Bonnie, a University of Virginia law professor who worked for a national commission that recommended decriminalizing marijuana in 1972, sees the public taking a big leap from prohibition to a more laissez- faire approach without full deliberation.
"It's a remarkable story historically," he said. "But as a matter of public policy, it's a little worrisome."
More than a little worrisome to those in the antidrug movement.
"We're on this hundredmile- an- hour freight train to legalizing a third addictive substance," said Kevin Sabet, a former drug policy adviser in the Obama administration, lumping marijuana with tobacco and alcohol.
Legalization strategist Ethan Nadelmann, executive director of the Drug Policy Alliance, likes the direction the marijuana smoke is wafting. But knows his side has considerable work yet to do.
"I'm constantly reminding my allies that marijuana is not going to legalize itself," he said.
Where California led the charge on medical marijuana, the next chapter in this story is being written in Colorado and Washington state.
Policymakers there are grappling with all sorts of sticky issues revolving around one central question: How do you legally regulate the production, distribution, sale and use of marijuana for recreational purposes when federal law bans all of the above?
Action up in the air
The Justice Department began reviewing the matter after last November's election. But seven months later, states still are on their own.
Both sides in the debate paid close attention when Obama said in December that "it does not make sense, from a prioritization point of view, for us to focus on recreational drug users in a state that has already said that under state law that's legal."
Rep. Jared Polis, a Colorado Democrat who favors legalization, predicts Washington will take a hands- off approach, based on Obama's comments. But he's quick to add: "We would like to see that in writing."
The federal government doesn't go after potsmoking cancer patients or grandmas with glaucoma. But it also has made clear that people who are in the business of growing, selling and distributing marijuana on a large scale are subject to potential prosecution for violations of the Controlled Substances Act — even in states that have legalized medical use.
There's a political calculus for the president, or any other politician, in all of this.
Younger people, who tend to vote more Democratic, are more supportive of legalizing marijuana, as are people in the West, where the libertarian streak runs strong.
Despite increasing public acceptance of marijuana overall, politicians know there are complications that could come with commercializing an addictive substance. Opponents of pot are particularly worried that legalization will result in increased use by young people.
Sabet frames the conundrum for Obama: "Do you want to be the president that stops a popular cause, especially a cause that's popular within your own party? Or do you want to be the president that enables youth drug use that will have ramifi cations down the road?"
Source: San Jose Mercury News (CA)
Copyright: 2013 Associated Press
Website: http://www.mercurynews.com/
Authors: Nancy Benac and Alicia A. Caldwell, Associated Press
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An abandoned town in Bosnia has been left to collapse
Serbs are kept in the dark about the fate of the bucolic village of Novo Banja, where a sewage treatment plant to treat Novo Banja's waste has failed. Nobody seems to know when they'll leave. Photo by: Andrey Sadovnikov/AFP/Getty Images
The writer Macmillan wrote in his classic novel The Old Men of Novo Banja, "All told it's a beautiful spot, and possibly soon our sweet home will be made no more."
Nearly a century later, the town of Novo Banja, a lush, agricultural patch nestled in a wooded valley near Bosnia's border with Serbia, has fallen into such disrepair that both the U.N. and warring factions of the Bosnian War have shown little interest in repairing it. According to the New York Times, a sewage treatment plant to treat Novo Banja's waste has failed, raising fears of epidemic disease and torrential flooding like the one in the Balkans this week.
The effects of urbanization, which has led to a recent influx of refugees from neighboring countries, have left the town abandoned by its residents as the damp, mud-brick buildings crumble around them. Some residents have already been forced to leave after neighbors advised them not to stay. But there is little prospect of finding housing elsewhere: "The region is divided," spokesman to Bosnia's president, Dragan Ćantović, told NPR, "so you're either between a village or here. And nobody can work, and then there is no way to improve the place."
Zera Kubac, a women's rights activist in Novo Banja, told NPR, "If you try to stay here [during an emergency], you will be a prisoner in your house." She noted that the city has only about 1,000 houses for its 50,000 residents.
But even the city's nearest neighbor is frozen in time: only two years after the war, a hotel in Novo Banja renovated from wartime wreckage remained standing, though it was unable to provide protection for the destroyed homes in town. "It is an indicator of how little respect there is," Gligorije Vidovic, a local historian, told the Guardian, "for what has happened since 1991."
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Cities will be key in the fight against climate change, UN chief says
By Florence Schulz|2019-10-10T12:39:56+00:00oktober 10th, 2019|Bernie Sanders, C40, cities, Climate Change, climate protection, Copenhagen, Donald Trump, European Green Deal, mayors, News, Paris Climate Agreement, United States, World mayors summit|
Mayors from all over the world are meeting in Copenhagen this week for the C40 World Mayors Summit. They have gathered to fight the so-called 'climate urgency' and are calling for a "Green New Deal" to be implemented worldwide. EURACTIV Germany reports.
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Trump launches 2020 reelection campaign, calling US 'envy of the world'
By Georgi Gotev|2019-06-19T08:17:56+00:00junij 19th, 2019|Bernie Sanders, Donald Trump, fake news, Joe Biden, Migration, News, Russia probe, US elections 2020|
President Donald Trump launched his 2020 reelection campaign Tuesday (18 June), whipping up a crowd of at least 20,000 with a nationalist boast about the US economy being the "envy" of the world and warning that opposition Democrats want to "destroy" t...
Komentarji so izklopljeni za Trump launches 2020 reelection campaign, calling US 'envy of the world'
Trans-Europe Express: Is Sánchez a man with a plan?
By Jorge Valero|2017-06-23T11:52:39+00:00junij 23rd, 2017|Albert Rivera, Beppe Grillo, Bernie Sanders, Bulgaria, Chile, Emmanuel Macron, France, George Soros, Greece, Heather Grabbe, Hungary, Italy, Jeremy Corbyn, Macedonia, Mariano Rajoy, migrants, News, Paolo Gentiloni, Pedro Sanchez, PSOE, Refugees, Serbia, Slovakia, Socialism, Spain, Susana Díaz, Tibor Navracsics, Trans-Europe Express, Turkey, Zoltán Kovács, Zoran Zaev|
Last month, Pedro Sánchez brought a new and unexpected result to the European ballot box. Sánchez returned to his post as secretary general of Spain's Socialist Party (PSOE) after a bitter campaign against Susana Díaz, the powerful president of Andalucía who was supported by the barons of the party.
Komentarji so izklopljeni za Trans-Europe Express: Is Sánchez a man with a plan?


World War II Bronze Bas Relief Medal.
Well executed painted bas relief carving of sailing ship. Thomas was active and lived in Maine, and is known for his ship carvings. Signed and dated (19)36 lower right.
Image: approx. 7" x 9".
Frame: approx. 11" x 18".


Talking to reporters can be daunting – here are tips to help you handle it.
To be successful in dairy farming today, you not only need to farm and manage your cows well, you also need to know how to tell your story to the public. That means talking to people through traditional media as well as social media.
When I was a journalist, I always appreciated those interview sources who answered my questions directly, and thoughtfully. I held them in higher esteem than those who gave me canned answers, or who didn't really answer my questions.
You want to be the authentic one, the one who comes across as a real person, as well as the truth bearer.
1. Trust that the media is out to do the right thing – but needs help.
My oldest son Jeremy is currently a political reporter for one of the larger papers in the country. Neither Jeremy nor I can recall a reporter who didn't try to report the truth.
That doesn't mean they always get the story right. You have to help them get there.
This starts with helping the reporter know what the real story is, and helping him or her find their way toward it.
You can do this, not by trying to educate the reporter, but by sharing your story, and showing its connection to the larger story.
2. Talk about the why before the what.
Let's say the story is about alleged cases of animal mistreatment, for example. You will not only want to talk about how animal care is one of the core values of dairy farms, but also about why good animal care makes both moral and economic sense for the vast majority of dairy farmers across the country. We shouldn't be shy about sharing our values.
3. Engage the reporter in a conversation.
Don't just state what you want to say. Ask them questions to gauge their comprehension of what you are saying, and to start a dialogue.
If your tone is right, this will show your inquisitiveness, not your desire to make the interview an inquisition. Ask your questions from a sincere desire to understand, and the reporter will see this as a sign of respect.
4. During the interview, stop and ask the reporter to summarize what they heard you say.
Often the reporter will give you the line they plan to quote you. If the quote is wrong, it's your chance to catch the error and edit it on the spot. Simply apologize for not being clear, then give the quote you really want.
5. Get in the last word.
If you hear the reporter wrapping up, be sure to summarize the main point you wished to convey. You could "flag" this by saying, "The most important thing in our discussion has been …" This often will be the quote the reporter will be sure to insert into the story.
6. Don't forget to close the loop.
Lastly, once the story is out, don't miss the chance to congratulate the reporter on a good story. Most reporters receive precious little feedback on their work, and when you do this in a constructive way, you can make yourself an ally for life.
What are your experiences and tips in talking with the media?
*Written by David Pelzer, Senior Vice President of Strategic Communications at DMI.
David has been working for America's Dairy Farmers for 20+ years and in his position oversees industry-wide crisis preparedness efforts and media relations. Before his time working with dairy farmers he was an editor of several national publications serving agriculture.


Gorgeous 5 bedroom, 4 bath home in the exclusive guard gated community of The Lakes Above Rancho Santa Fe. This home has a bright and open floor plan, with one full bedroom and bath downstairs. The large gourmet kitchen includes a spacious island, lovely cabinetry, stainless steel appliances, and beautiful granite counter tops. The luxurious master retreat features a spa-like bathroom. 3 car tandem garage, tank-less water heater, 2.25 KW solar system. The back yard is perfect for entertaining and outdoor living. Deluxe outdoor lounge area with TV, SYNLawn putting green, BBQ island, spa, fire pit, and views.
I'd like to know more about 8754 Herrington Way.


Punicic Acid health benefits includes promoting heart health, fighting cancer, acting as natural aphrodisiac, controlling and repairing sun and environmental damage on skin, promotes flawless skin, helps increase immunity, helps treat arthritis, improves memory, helps with hair growth and helps with weight loss.
Punicic acid is a relatively new find; it is a poly-saturated fatty acid. The therapeutic and medical benefits are still being studied and experimented. Laboratory studies of punicic acid have found it to be instrumental in the treatment of chronic diseases such as Alzheimer's, dementia, macular degeneration. It is a potent antioxidant and has anti-inflammatory properties as well.
The acid is considered essential to consume. The anti-inflammatory properties are necessary to ward off various health-damaging factors such as infectious bacteria, free radicals, and cancerous cells. In the article, you will find further health benefits associated with Punicic Acid.
You can reap punicic acid in abundance from the Pomegranate seed oil and snake gourd. Apart from this, it is rich in antioxidants, vitamin C and vitamin B5, polyphenol, fiber, potassium and rare Omega-5 fatty acids. The incredible thing about this oil is it has rich mineral content and has many health benefits.
For instance, the seed oil contains a fatty acid known as Punicic acid, it is anti-cancer, anti-inflammatory, prevents cardiovascular diseases, controls high blood pressure, ensures flawless skin and helps in hair growth and prevents damage. Also, a lot of laboratory work is underway to establish its various uses, dosage, and precautions.
This article will highlight the various health and beauty uses of Punicic acid extracted from pomegranate seed oil.
Punicic acid helps regulate cholesterol level in the body, and therefore it can prevent heart diseases caused by high cholesterol levels. It also controls high blood pressure.
The anti-oxidant properties of punicic acid prevents cell damage and restrict the growth of tumors, lab studies carried out n rats have shows significant antitumor affects on breast, colon and prostate cancer cells.
Multiple studies demonstrated the restraining effect of punicic acid on the multiplication of cancer cells in the breast; the omega-5poly saturated chains have also executed a programmed death of cancer cell. Regular use of punicic acid has shown to reduce growth of recurrent prostate cancer. It is the most widespread cancer type of men. In lab study revealed the inhibiting effect of punicic acid on the growth of cancerous cells.
One of the most valuable benefit of punicic acid is it doesn't only protects sun damaged and aged skin from further damage, but it also enhances skins ability to repairs itself. It naturally changes the look of dull aged skin to firmer and younger.
It increase the number of keratinocytes cells, they make skin grow thick to enhance its barrier function against harmful UV rays and harsh environmental factor. We can safely say punicic acid works as an anti ageing treatment from both inside and outside, applying it n the skin provides UV protection while it boosts skins vitality from the inside and fights sun damage and wrinkles.
A research study conducted in Queen Margaret University in Edinburgh has found it to be a natural Viagra, it did not only increase the level of testosterone but had a positive effect on blood pressure and mood. Increase testosterone level is an indicator of sexual desire.
It is also beneficial in preventing and treating erectile dysfunction, animal studies have shown it to be a natural remedy for impotence.
It is rich in antioxidants, which helps protect the skin from harmful effects of free radicals, repairs the damaged and aged skin and promote collagen production. It also helps regulate the sebum production thus preventing black heads and acne from popping on the skin.
The nutrient rich, moisturizing oil, eaves the skin properties of punicic acid rejuvenates skin and leaves it soft and supple after application.
The anti inflammatory and antioxidant properties of punicic acid strengthen the immune system of your body to fight off infections and germs.
About 3 million cases of arthritis are reported each year in US only, punicic acid is one of the treatments prescribed for the debilitating disease, and it's full of antioxidants called flavonoids, these antioxidants have anti-inflammatory properties.
Research conducted on animals has established that an oral consumption of it reduces inflammation and joint pain considerably. It also controlled the severity of arthritis.
If you are already on arthritis medication you should consult your doctor before adding punicic acid supplements in your diet.
Polyphenols are found abundantly in punicic acid, evidence based research and alternate medicine usage data suggests that the polyphenols may provide long lasting prevention against surgery induced memory loss.
The animal study data conducted by the Department of Psychology at Loma Linda University have shown that a regular consumption of punicic acid helps delay the onset and slow down the progression of dementia.
The in-vitro studies on lab rats have shown it to be very efficient in reduction of bad fats from the body. The flavanoids present in punicic acid reduces cholesterol level in a body, thus resulting in healthy weight loss.
It is an amazing serum for hair growth and it also enhances the look and health of hair. It makes hair strong, lustrous and healthy; punicic has high vitamin content when it is massaged on to the scalp it increases blood circulation and gets absorbed into the scalp, it promotes healthy blood vessels. It has a natural moisturizer and provides ample nourishment to dry and damaged hair.
Punicic acid doesn't only affect the look of hair but it takes care of the health of scalp and hair, therefore it fights off almost all hair problems, including dullness, itchy scalp, dandruff, hair fall and thinning of hair.
So there you go – all the incredible benefits you can enjoy just by adding punicic acid in your daily diet!


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UNOOSA / GEO Discovery Day in Geneva
The United Nations Office for Outer Space Affairs (UNOOSA) and the Group of Earth Observations (GEO), with the support of DigitalGlobe, are organizing the Discovery Day 2016 meeting in Geneva on the 11th of May 2016 at the headquarters of the World Meteorological Organization. It will provide a high-level perspective on the benefits and applications of space-based imagery and space-derived geospatial information to monitor the effects of climate change, in environmental and natural resource management, and to respond to emergencies and crisis events.
The organizers will present how collaboration around the provision of VHR satellite imagery and geospatial analysis can support the work of various UN entities and other international organizations in implementing their respective mandates and how it can facilitate inter-agency coordination. DigitalGlobe will demonstrate state-of-the-art satellite Earth observation, including WorldView-3, launched into orbit on 13 August 2014, geospatial big data and crowdsourcing with applications considered relevant for the Geneva-based international organizations. The event is also an opportunity to identify opportunities of collaboration between GEO and United Nations entities.
Ms. Simonetta Di Pippo, Director of UNOOSA and a representative of the Office of the GEO Secretariat will open the event, which will also provide additional opportunities for bilateral or multi-lateral exchanges.
Discovery Day in Geneva marks the second of a series that started in Rome in December 2015 co-organized with FAO and UNECE. UNOOSA and DigitalGlobe are already working at future events in other United Nations key locations worldwide.
11406-DG-GENEVA-AGENDA-9b.pdf (3.41 MB) 3.41 MB


Dolphins vs. Falcons: How do they match up in Week 6?
October 13, 2017 2017 Regular season.
How do the Miami Dolphins and Atlanta Falcons match up for Sunday's NFL Week 6 tilt at the new Mercedes-Benz Stadium?
How can Miami Dolphins solve big problem: lack of big plays?


UN Secretary-General Antonio Guterres on Wednesday expressed concern over the "growing risks of a humanitarian catastrophe" in the event of a full-scale military operation in the northern Idlib province of Syria.
Guterres' statement on Wednesday followed the briefing a day before by the director of operations for UN humanitarian affairs John Ging to the Security Council. Ging warned such a government offensive in Idlib "has the potential to create a humanitarian emergency at a scale not yet seen" in the seven-year civil war, Xinhua news agency reported.
The United States, Britain and France have warned that they will respond "appropriately" to any chemical weapons attack in Idlib, a warning repeated at the Security Council on Tuesday by the three countries.


Townsend Design - Sight Unseen - Heron floor and table lamps.
We were excited to see a brand new product from Townsend Design: the powder-coated Heron floor and table lamp, available in a range of perfect hues. With our favorite finds from elsewhere around town.
*Note: The Heron Lamp line is no longer available.


The Internet has brought about innovations about how we communicate and is shaping the very culture of not only our country, but the entire world. It has become so easy to acquire information for anything you may want to do or information that we seek to keep private. Internet and social media are the fastest developing innovations of the 21st century. It is an innovation that has only been available for the last twenty years. Its advancements are still rising, but with advancements come different issues. Being a YouTuber and a social media influencer, the Internet would be an important asset in my life. I would rely on it for the aspects of different clothing companies and communication, including platforms such as Instagram, YouTube, and Facebook. As the Internet evolves, its success will be reliant on our awareness of how to properly market ourselves, as well as of how our personal information can be used. This presentation will discuss how social media can affect our lives and raise awareness of the risks that are associated with it as well as how to take precautions against these risks.