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Mary Lou Caspers
Campus: McNichols Campus
Building: Chemistry
Email: casperml@udmercy.edu
Basic & Advanced Biochemistry
General Chemistry Laboratory
Aluminum / Alzheimer's Disease
Effects of Metal Ions on Brain or Body
Lead and Aluminum in the Environment
Neurochemistry
Ph. D., Biochemistry, Wayne State University School of Medicine, 1977
B.S., Chemistry, University of Detroit, 1972
After being an undergraduate student at the University of Detroit, Caspers was very pleased to join the faculty in the Department of Chemistry and Biochemistry after completing her Ph.D. Caspers was the first woman faculty member in the Department. She has enjoyed working with undergraduate students in a small, Catholic university and has celebrated their successes over the years.
Brain enzymes and neurochemistry, in general; Kinetics of the Sodium-Potassium ATPase, pectinase and polygalacturonase
Teaching Experience:
She has taught the upper division biochemistry courses as well as chemistry for nursing students and the first freshman chemistry laboratory course. In addition, She has taught a neurochemistry course for our graduate students and senior undergraduate students. She has had several publications related to innovative teaching methods (listed below).
Brown, R.K., Caspers, M.L., Lull, J.M., Vinogradov, S.N., Felgenhauer, K. and Nekic, M. (1977). Carrier Ampholyte Distribution in Isoelectric Focusing. J. Chromatogr. 131, 223-232.
Brown, R.K., Caspers, M.L. and Vinogradov, S.N. (1977). Carrier Ampholyte Distribution. In Electrofocusing and Isotachophoresis (Radola, B.J. and Graesslin, D. Eds.) Walter DeGrutyer and Co., Berlin-New York, pp 87-96.
Caspers, M.L., Posey, Y. and Brown, R.K. (1977). Separator Isoelectric Focusing - An Improved Method of Protein Analysis and Purification. Anal. Biochem. 79, 166-180.
Caspers, M.L. and Chrambach, A. (1977). Natural pH Gradients Formed by Amino Acids: Ampholyte Distribution, Time Course, Use in Electrofocusing of Protein, Relation to pH Gradients in Isotachophoresis, Separator Effects. Anal. Biochem. 81, 23-39.
Caspers, M.L. and Siegel, G.J. (1980). Inhibition by Lead of Human Erythrocyte (Na+ + K+)-Adenosine Triphosphatase Associated with Binding of 210Pb to Membrane Fragments. Biochim. et. Biophy. Acta, 600, 27-35.
Caspers, M.L. (1980). Book Review: Electrophoresis: A Survey of Techniques and Applications. Part A. Techniques, J. Amer. Chem. Soc., 102, 7408.
Caspers, M.L. (1982). Inhibition by Lead of Phenylethanolamine-N-Methyltransferase. Biochem. Pharmacol., 31, 1985-1988.
Caspers, M.L. and Diglio, C.A. (1984). Expression of g-Glutamyltranspeptidase in a Transformed Rat Cerebral Endothelial Cell Line. Biochim. et Biophy. Acta, 803, 1-6.
Unni, L.K. and Caspers, M.L. (1984). Inhibition of Bovine Plasma Amine Oxidase by Lead. Biochem. Pharmacol. 33, 2149-2151.
Unni, L.K. and Caspers, M.L. (1985). Inhibition of Bovine Brain Monoamine Oxidase by Lead. Biochem. Pharmacol. 34, 2563-2566.
Grammas, P., Caspers, M.L., Diglio, C.A., Giacomelli, F. and Weiner, J. (1985). Regulation of Cerebrovascular Gamma-Glutamyltranspeptidase by Adrenergic and Cholinergic Agonists. Biochem. Pharmacol. 34, 4177-4179.
Caspers, M.L., Schwartz, R.D., Labarca, R. and Paul, S.M. (1987). Autoradiographic Visualization and Characterization of [3H]-Ouabain Binding to the (Na+ + K+)-ATPase of Rat Brain and Pineal. Brain Res. 409, 335-342.
Caspers, M.L. and Grammas, P. (1988). The Effect of Fatty Acids on [3H]-Ouabain Binding to Cerebromicrovascular (Na+ + K+)-ATPase. J. Neurochem., 50, 1215-1219.
Hart, M.A., Swisher, J.A. and Caspers, M.L. (1989). Alterations in Plasma Amino Acids and Hepatic Enzymes in the 4-Pentenoic Acid Model of Reye's Syndrome. Biochem. Pharmacol. 38, 1696-1698.
Caspers, M.L., Kwaiser, T.M. and Grammas, P. (1990). Control of [3H]Ouabain Binding to Cerebromicrovascular (Na++K+)-ATPase by Metal Ions and Proteins. Biochem. Pharmacol. 39, 1891-1895.
Grammas, P. and Caspers, M.L. (1991). The Effect of Aluminum on Muscarinic Receptors in Isolated Cerebral Microvessels. Res. Commun. Pathol. Pharmacol. 72, 69-79.
Grammas, P., Kwaiser, T.M. and Caspers, M.L. (1992). Regulation of Amino Acid Uptake into Cerebral Microvessels. Neuropharmacol. 31, 409-412.
Caspers, M.L. (1992). Book Review: Frontiers in Supramolecular Organic Chemistry and Photochemistry, J. Polym. Sci. Part A: Polym. Chem. 30, 593.
Caspers, M.L., Bussone, M., Dow, M.J., Ulanski II, L.J. and Grammas, P. (1993). Effects of Acute Hypertension and Fatty Acids on the Cerebromicrovascular (Na++K+)-ATPase. Brain Res. 602, 215-220.
Caspers, M.L., Kwaiser, T.M., Dow, M.J., Fu, M.J. and Grammas, P. (1993). Control of the (Na++K+)-ATPase under Normal and Pathological Conditions. Mol. Chem. Neuropathol. 19, 65-81.
Caspers, M.L., Dow, M.J., Fu, M.J., Jacques, P.S. and Kwaiser, T.M. (1994). Aluminum-Induced Alterations in [3H]Ouabain Binding and ATP Hydrolysis Catalyzed by the Synaptosomal (Na+ + K+)-ATPase. Mol. Chem. Neuropathol., 22, 43-55.
Caspers, M.L. (1994). Biopolymers: Prospects for the Future. In: 25th Anniversary Symposium of the Polymer Institute (Frisch, K.C. and Eldred, E.W., Eds.) Technomic Publishing Co., Lancaster, pp 257-166.
Schroeder, T.M. and Caspers, M.L. (1996). Kinetics of Aluminum-Induced Inhibition of Delta-Aminolevulinic Acid Dehydratase in Vitro. Biochem. Pharmacol., 52, 927-931.
Rossi, N.F., O'Leary, D.S., Scislo, T.J., Caspers, M.L. and Chen, H. (1997) Central Endothelin 1 Regulation of Arterial Pressure and Arginine Vasopressin Secretion via the AV3V Region. Kidney Internatl. 52, Suppl. 61, S22-S26.
Roberts-Kirchhoff, E.S. and Caspers, M.L. (2001) Dialogues as Teaching Tools in the Biochemical Sciences. Biochem. Mol. Biol. Ed. 29, 225-228.
Caspers, M.L. and Roberts-Kirchhoff, E.S. (2003) An Undergraduate Laboratory Course with an Emphasis on a Research Experience. Biochem. Mol. Biol. Ed. 31, 303-307.
Caspers, M.L. and Roberts-Kirchhoff, E.S. (2003) Incorporation of Ethical and Societal Issues in Biochemistry into a Senior Seminar Course. Biochem. Mol. Biol. Ed. 31, 298-302.
Grants and Awards:
1972 American Chemical Society Award for Achievement in Chemistry, University of Detroit
1972 Kappa Beta Gamma Senior Scholarship Award for Graduating Woman with highest scholastic average, University of Detroit
1974-1975 Member, Graduate Fellowship & Scholarship Committee, Wayne State University
1976-1977 Recipient, University Graduate Fellowship, Wayne State University
1977-1978 Muscular Dystrophy Association Postdoctoral Fellowship (declined to take position at University of Detroit)
1978 (summer) Visiting Research Investigator in Neurology, University of Michigan Medical School
1978-1981 American Chemical Society Petroleum Research Fund Grant, "The Effect of Lead on the Enzymatic Synthesis and Degradation of Certain Neurotransmitters"
1981 National Reye's Syndrome Foundation, Michigan Region Grant, "Development and Evaluation of Suitable Reye's Animal Model"
1982 National Science Foundation Travel Award to attend 12th International Congress of Biochemistry, Perth, Western Australia
1983-1984 Sigma Delta Epsilon, Graduate Women in Science, Eloise Gerry Fellowship, "Determination of Catecholamines and Metabolites in Brain Preparations from a Reye's Syndrome Animal Model"
1984-1985 Guest Researcher for Academic Year, National Institute of Mental Health, Bethesda, MD
1986 Nominated for University of Detroit President's Award for Excellence in Teaching and Research
1986 Keynote Speaker, University of Detroit, Engineering & Science College Honors Convocation
1986 University of Detroit-Faculty Development Award, "Lead Poisoning and the Blood-Brain Barrier"
1986 American Society for Biochemistry and Molecular Biology Travel Award to attend 14th International Congress of Biochemistry in Prague, Czechoslovakia
1988-1991 NIH research grant, "Control of Cerebrovascular (Na+ + K+)-ATPase in Hypertension"
1990-1992 American Health Assistance Foundation research grant, "Aluminum and (Na++K+)-ATPase Control in Aging Neurons"
1990 University of Detroit, College of Engineering & Science, Teacher of the Year
1990 Invited Speaker, Fifth International Symposium, "Molecular Sciences in Neurodegeneration and Regeneration" Biochemistry and Biophysics of Stroke, Neurotrama and Other Neurological Disorders, Bristol, England
1991-1992 Sigma Tau S.p.A., Italy research grant, "Effect of Acetyl-L-Carnitine on the Synaptosomal (Na++K+)-ATPase"
1993-1995 American Federation for Aging Research research grant, "Influence of Estrogen on High Affinity Choline Uptake during Aging"
1993-1995 Sigma Tau S.p.A., Italy research grant, "Effect of Propionyl-L-Carnitine on the Synaptosomal (Na++K+)-ATPase"
1993-1996 University of Detroit Mercy Center of Excellence in Environmental Engineering and Science, EPA research grant "Alterations in Blood Cell Enzymes following Exposure to Aluminum"
1995 University President's Award for Excellence in Teaching and Research
1995 Award of Appreciation from Faculty for Undergraduate Neuroscience for dedication to undergraduate education in neuroscience
1995 NSF Instrumentation and Laboratory Improvement Grant "Use of a Personal Densitometer for the Mini-Project Approach to Curriculum Enrichment in the Undergraduate Biochemistry and Physiology Laboratories"
1995 Camille and Henry Dreyfus Special Grant Program in the Chemical Sciences "Incorporation of Mini-Research Projects into the Undergraduate Biochemistry Laboratory"
1995 Pfizer Summer Undergraduate Research Fellowship Mentor - fellowship awarded to Jamira Jones to work in M.L.C.'s laboratory
2000 NSF Instrumentation and Laboratory Improvement Grant "Improving Undergraduate Chemistry by Incorporation of NMR Spectroscopy Across the Chemistry Curriculum" (co-principal investigator)
1999 Pfizer Summer Undergraduate Research Fellowship Mentor – fellowship awarded to Tanvi Desai to work in M.L.C.'s laboratory
2001 University of Detroit Mercy Distinguished Faculty Award
2002 Jesuit 100 Association Magis Award
2002, 2003 Awards of Appreciation from Faculty for Undergraduate Neuroscience for dedication to undergraduate education and service to the organization
2004 University of Detroit Mercy, College of Engineering and Science Cornerstone Award
2004 Educator of the Year, Faculty for Undergraduate Neuroscience
2004 Faculty for Undergraduate Neuroscience FUN Fellow Award - Honoring ten years of Membership in the Faculty for Undergraduate Neuroscience (Served as Councilor, Chair of Travel Award Committee and Secretary)
2008 Recipient of UDM Jesuit 100 Association, Faculty Summer Stipend for Course Development – developed "Food Chemistry" course for non-science majors


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Residents' Bill Of Rights
Resident Advocacy
Shalom Manor History
Shalom Manor Long-Term Care Home was incorporated in 1966 by the deacons of Classis Hamilton of the Christian Reformed Churches in the Hamilton-Niagara Region, and was known as "Classis Hamilton Homes for the Aged, Inc.," operating as "Shalom Manor." The mandate of the deacons was to open and operate a home for elderly members of the Christian Reformed Churches in the area and to raise funds for the support of the home.
Significant developments since the time of incorporation include:
1979 The opening of a 74-bed Home for the Aged with only private financing.
1981 The addition of a new dining room.
The addition of a 28-bed two-level wing.
1992 The addition of a 30-bed nursing home wing (Sunrise Court), auditorium, and administrative offices.
1996 Formal recognition as a 132-bed Home for the Aged.
1999 67 beds were classified as "D" Beds.
2001 The construction of 98 life-lease condo apartments, known as "Shalom Evergreen Terrace" started, for completion in November 2002.
2002 Response to MOHLTC "D" Bed Submission proposed a $12-million redevelopment of all of Shalom Manor except the 1992 nursing wing addition (which will be renovated to maintain "A" standard). Approval received.
2003 Rebuild Shalom Manor to 112 new beds and renovate Mapleview.
2005 Shalom Manor reopens 144 beds on February 8. Demolished old building.
2006 Last phase built and opened September 28 including 36 retirement apartments (Shalom Gardens), new administration offices, auditorium, and café.
Our four-level, 36-unit retirement living complex, known as Shalom Gardens Apartments, complements the "continuum of care" vision shared by the Board of Directors and embraced by the Ministry of Health are now open. These units consist of a bedroom, sitting room, kitchenette, balcony, and bathroom with laundry facilities and lounges on each floor. These suites come with a meal plan, housekeeping, and nurse supervision amenities.
Shalom Manor & Shalom Gardens is linked to Evergreen Terrace, a neighbouring life-lease complex, by an enclosed passageway.

redpajama_set_name: RedPajamaCommonCrawl


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Analyzing WWII Military Service Record Envelopes | Wisconsin Historical Society
Classroom Material
Analyzing WWII Military Service Record Envelopes
Wisconsin World War II Stories: The Struggle
Grade level: Secondary
Duration: One class period
There are 30 Military Service Record Envelopes from the Town of Burlington (Racine County, Wisconsin) that were randomly selected from the more than 400 service envelopes for Burlington during the War years. These are not official service records. The Racine County War Records Committee instructed volunteers to obtain a "complete personal history and service record... for every man or woman." Volunteers were coached on the necessity of accuracy and care. Information was obtained through canvassing city blocks. The initial canvassing was "scheduled for completion by December 15, 1943," with follow-up information to be added later.
Analyze primary source documents
Understand the contributions of communities and families to World War II
Teacher Caution: While these records are an interesting addition to World War II studies, there are drawbacks to using them. The small sample means that statistical validity can not be assured. Please use the strengths and weaknesses of this source as a foundation for discussing with your students the importance of evaluating sources. Some questions you might want to consider for such a discussion are:
Of what value are these records?
What are the possible shortcomings of using these records instead of official service records?
How might these records be insufficient for making generalizations?
The first part, The Struggle, in the Wisconsin World War II Stories series helps us recognize the importance of oral history in interpreting our past. In listening to these World War II veterans, we learn that the personal experience of history's many and varied actors can enrich our understanding of a given historic moment. In the following lessons you will have an opportunity to explore World War II, as witnessed by Wisconsin veterans. These lessons are intended to make history come alive for you in much the same way as the telling of their stories did for the veterans.
The videos and the coordinated lesson plans can be used in various ways. The lessons can be combined with part or whole use of the videotapes or online video clips, or the lessons can "stand alone." The five video series and lesson plans can constitute a complete World War II unit. Alternatively, any one component may be added as enrichment to an existing unit or program.
Primary Source Documents: Military Service Record Envelops, Racine County, Wisconsin, War Records Committee (PDF, 1.85 MB)
Each student will be assigned one envelope to analyze. After examining the information on the envelopes, students should complete the following exercise.
Using one envelope, record possible categories of analysis for study about World War II veterans and the communities where they lived.
Using the ideas you discussed in question one, consider the contributions of your own hometown. How might you go about conducting research on your town's World War II service? How can you learn the individual stories of the men and women who served?
Individual Assignment
Choose one of the following roles and formats to write about the human commitment and cost required to conduct a war of the magnitude of World War II. Include ideas from what you have learned in the exercise above.
government official directing the production of a newsreel to be made immediately after President Roosevelt's Address to Congress (December 8, 1941)
the parent of five sons who have been drafted (there were several such families in Racine County, alone), writing a letter to the editor of the local newspaper
a peace activist who has chosen to resist the draft, speaking to a sympathetic audience in Milwaukee, Wisconsin, in February of 1941
a citizen whose country has been liberated from Axis forces, writing a letter "To the American People," in August of 1944
Many of the Service Record Envelopes contained newspaper clippings about the individual who served. Research your community's newspapers from 1940-1945 to construct a profile of your hometown's experiences during World War II.
Interview a World War II veteran to learn one individual's story. Write your interview, following the Library of Congress guidelines or Oral History Tool Kit for directions on how to conduct an oral history interview.
National Standards for United States History: Exploring the American Experience
(National Center for History in the Schools, UCLA)
Era 8, Standard 3
The Origins and Course of World War II, the Character of the War at Home and Abroad, and its Reshaping of the U.S. Role in World Affairs. Students should be able to:
Standard 3B
The student understands World War II and how the Allies prevailed.
THEREFORE, THE STUDENT IS ABLE TO
5-12 Explain the major turning points of the war and contrast military campaigns in the European and Pacific theaters.
Standard 3C
The student understands the effects of World War II at home.
5-12 Explain how the United States mobilized its economic and military resources during World War II.
7-12 Evaluate how minorities organized to gain access to wartime jobs and how they confronted discrimination.
Wisconsin's Model Academic Standards for Social Studies
Standard A - Geography: People, Places, and Environments
BY THE END OF GRADE 12 STUDENTS WILL
A12.1 Use various types of atlases and appropriate vocabulary to describe the physical attributes of a place or region.
A12.13 Explain the major turning points of the war and contrast military campaigns in the European and Pacific theaters.
Standard B - History: Time, Continuity, and Change
B.12.1 Explain different points of view on the same historical event, using data gathered from various sources, such as letters, journals, diaries, newspapers, government documents, and speeches.
B.12.2 Analyze primary and secondary sources related to a historical question to evaluate their relevance, make comparisons, integrate new information with prior knowledge, and come to a reasoned conclusion.
B.12.6 Select and analyze various documents that have influenced the legal, political, and constitutional heritage of the United States.
B.12.7 Identify major works of art and literature produced in the United States and elsewhere in the world and explain how they reflect the era in which they were created.
B.12.15 Identify a historical or contemporary event in which a person was forced to take an ethical position, such as a decision to go to war…and explain the issues involved.
B.12.17 Identify historical and current instances when national interests and global interests have seemed to be opposed and analyze the issues involved.
B.12.18 Explain the history of…racial and ethnic discrimination, and efforts to eliminate discrimination in the United States and elsewhere in the world.
These lesson plans are designed to be used with Wisconsin World War II Stories: Part I: The Struggle, a video series created by Wisconsin Public Television and the Wisconsin Historical Society, in association with the Wisconsin Dept. of Veterans Affairs. The lessons in this part of Wisconsin World War II Stories span interest areas and levels. They include geography, technology, and human interest studies, and draw upon a wide array of social studies skills. Information on the series can be found at http://wpt2.org/wisconsinstories/worldwar2/
Author: Victoria Zuleger Straughn.
A Passion to Preserve: Gay Men as Keepers of Culture