Semana Santa in the Bay Islands is the biggest week of the year. The week leading up to Easter Sunday is traditionally a week off of school in the region, plus many businesses close entirely or limit their opening hours to celebrate. In the Bay Islands, you won't find any tourism-related businesses closed during this week because they are all at full tilt!
Easter Week, Holy Week, Semana Santa - they're all the same thing. Throughout Central and South America, plus much of the Caribbean, Semana Santa is a week filled with festivities and family fun. In the Bay Islands, we receive a huge influx of tourists from mainland Central America to enjoy a week on the beach. Each of the Bay Islands sees an uptick in tourism during this week, but Roatan typically sees the largest increase.
Roatan receives cruise ships regularly at its two ports, plus a number of international flights direct to the island throughout the week. Add in the many additional tourists for Semana Santa who arrive via domestic flights or the ferry, and you'll notice a big change for the island. West Bay Beach and West End in particular see much larger crowds during Semana Santa.
Keep in mind that if you are visiting the islands during this time, you should book any and all activities in advance to ensure you don't miss out on something because it's already full. Hotels and resorts will be booked well in advance, and vacation rentals are immensely popular during Semana Santa - so book early to get your first choice!
If you are staying on West Bay Beach or in West End, it might be a bit louder than normal as celebrations and festivities will go later into the night. If you're a light sleeper, you might want to consider staying farther away from these main hubs of activity. Otherwise, join in on the fun!
There will be lots of special events and celebrations scheduled throughout the week for each island. Check with your hotel or vacation rental manager for details so you don't miss out on fantastic live music, fun parties, and lots of great energy as the islands come alive with happy celebrations.
You will see vendors selling all kinds of food, drinks, and souvenirs throughout Semana Santa. Go ahead and try something new, chat with the people next to you on the beach and in the bar, and revel in the festive feeling of Semana Santa in the Bay Islands.


Beautifully landscaped small outdoor spaces can make a sale. Even a 3m x 3m space can be transformed into an oasis, says Nichola Vague, landscape architect for Zones.
Larger is better, but even tiny areas of otherwise dull and/or wasted space can be turned into indoor-outdoor living, barbecue areas or just a tranquil space to sit.
Patios and decks are super important for properties in buyers' minds. Even a small space can become a selling point.
Planned well, outdoor landscaping can double the size of the living area. Even a balcony can be transformed into a chic space with a bit of creativity.
Thanks to retractable roofs, outdoor heating solutions, and PVC curtains these spaces can also be used 12 months of the year.
Martin Cooper, managing director of Harcourts Cooper & Co on the North Shore, says homeowners can usually double every dollar spent on landscaping small outdoor spaces.
"In today's changing styles of living, small outdoor spaces can be an extension of the living space of the home or unit," he says.
"With the use of rain and sun shelter covers, outdoor lighting and outdoor heating combined with Auckland's pretty moderate climate, we are finding there is a big uplift in interest from buyers for beautifully landscaped spaces."
Kiwis want to entertain even when they have a small space, says Cooper. So a cleverly designed tiny space is a real selling point.
What's more, don't underestimate the effect of buyers looking out the window at an open home and seeing a beautiful space instead of an ugly fence or neighbour's property, says Cooper.
Landscaping increases the number of potential buyers and, as a result, the price at auction – especially when two or more buyers have fallen in love with the property.
"Our more entrepreneurial agents are (recommending to vendors) to get landscaping people in to enhance the outdoor spaces," says Cooper.
People buy a home because it feels right. If you have a peaceful Zen-like feeling in the outdoor space it sells better."
Creating these spaces not long before selling makes them appear fresh – especially if old trampolines, worn furniture and overgrown or outdated plants are replaced.
Landscaper Vague says the key is to start with a plan and keep your palette of materials and plantings simple. "If you do that you can get some quite striking results. It is a lot more cohesive.
"I start with a critical look at what's there already. If there is a lot don't be afraid to rip stuff out.
"Next give the place a good clean and a coat of paint to fencing or retaining walls," says Vague. "Then you know what you are working with."
The design needs to tie in with the house and its the surroundings. Even if the space available is a glorified backstep area colourful pots will transform it into desirable space, she says.
Vague has never been employed to design a backdoor step, but has helped friends transform theirs. "Don't use anything too small. Use something with a bit of scale. As soon as you bring pots outside they shrink."
the plants need to be luscious and young. Having a series of matching pots and plants can be very dramatic if planned well.
There may be building needed. A variety of screens or trellis can transform a small space. It's also possible to plant to create privacy. Vertical gardens that add colour and interest to otherwise boring walls are popular.
Cooper says more of his agents are seeing owners getting really creative with small spaces. Water features are popular, he says, and increasingly homeowners are even fitting outdoor speakers to add ambience.
If you're selling you may not need to buy the furniture. This can be supplied by a home staging company. This fits with what Cooper is seeing at open homes.
Although some homeowners can plan and execute their own DIY small space, it's usually best to employ a professional. Paying for a landscape architect to do a plan for a small outdoor space would start from about $1000, says Vague.
Additional costs will depend on the size of space and materials and plants used. If you don't have much of a budget garden planning apps and staff at garden stores can help. Pinterest could be a source of many ideas.
Vague's top tips for small outdoor spaces: keep it simple, keep in mind what the space will be used for, and be bold.


April 2012, Boy of Bone, from the book Boy of Bone: Twelve Stories Inspired by the Mutter Museum. Author K. R. Sands created a collection of short fiction inspired by the displays of pathological human anatomy and other medical oddities at the famous Mütter Museum in Philadelphia. .
April 12, The Pump Twin, from the book Boy of Bone: Twelve Stories Inspired by the Mutter Museum. Author K. R. Sands created a collection of short fiction inspired by the displays of pathological human anatomy and other medical oddities at the famous Mütter Museum in Philadelphia. .


Joyce Patterson aged 64 died on 8 November 2017 after being struck by a train, shortly after she absconded from St Helier Hospital.
On 24 October 2018, the Assistant Coroner for Inner West London, Darren Stewart, concluded that Mrs Patterson's death was contributed to by neglect. Her family were represented at the inquest into her death by medical negligence solicitor Fiona Huddleston.
Mrs Patterson was admitted to St Helier Hospital (Epsom and St Helier University Hospitals NHS Trust) on 2 November 2017 having taken an overdose. She was treated for the physical effects of the overdose before being transferred to a psychiatric assessment unit at Springfield Hospital (South West London and St George's Mental Health NHS Trust) on 7 November.
A mental health assessment could not take place because of the deterioration in her physical condition, which meant that she had to be transported back to St Helier Hospital. She was escorted by a health care assistant (HCA) that evening. The ambulance crew were made aware that she whilst she was not detained under the Mental Health Act, she should not be allowed to leave the hospital.
She was transferred from the Accident & Emergency department to the Surgical Assessment Unit of St Helier Hospital (she was not due to undergo surgery but there were bed constraints at the hospital) in the early hours of 8 November. The HCA then left, even though Mrs Patterson had not been seen by a member of the psychiatric liaison team (nor was she subsequently).
At around 11.10am Mrs Patterson attempted to leave the ward. She was told to return to her room by a HCA, who, despite being allocated to Mrs Patterson, was not aware of her mental health history and did not tell anyone what had just occurred.
Some ten minutes later, Mrs Patterson attempted to leave for a second time. She was pursued by the HCA and by her designated nurse. They were unable to persuade her to stop and by the time security arrived Mrs Patterson had left the premises. Police attended the hospital but a short time later Mrs Patterson was reported to have died at St Helier train station.
There were two pre-inquest review hearings which determined the scope of the inquest and the witnesses required to give evidence. The inquest took place over four days, with an adjournment of two weeks before the final day. The coroner accepted that Article 2 of the European Convention on Human Rights was engaged.
The coroner concluded that there were multiple failures and that the cumulative effect of these failures, constituted a gross failure to deliver basic medical care.
In particular, he criticised the communication between the two hospitals as to Mrs Patterson's mental health status and needs, which meant that adequate arrangements to care for those needs were not put in place.
The coroner also criticised the response of the HCA following the first attempt and the inadequate response of the nursing staff following her second absconding attempt, to prevent Mrs Patterson's departure.
The coroner was satisfied that both trusts had made a number of efforts to address the failings. However, he asked for a consolidated report incorporating the matters raised at the inquest.
Medical negligence solicitor Fiona Huddleston, who represented Mrs Patterson's family, said: "The family and I welcome the coroner's conclusion that Joyce's death was contributed to by neglect and the recognition that there were many failings in Joyce's care.
Leigh Day instructed Jim Duffy of One Crown Office Row.


text:
BioQuick News--Life Science News from Around the Globe
BioQuick Japanese Edition
Study Reveals Domestic Horse Breed (Cleveland Bay) Has Third-Lowest Genetic Diversity, Just Higher Than Friesian & Clydesdale Breeds
Wed, 12/18/2019 - 21:55 — bioquicknews
A new study by Dr. Gus Cothran, Professor Emeritus at the Texas A&M School of Veterinary Medicine & Biomedical Sciences (CVM), has found that the Cleveland Bay (CB) horse breed has the third-lowest genetic variation level of domestic horses, ranking above only the notoriously inbred Friesian and Clydesdale breeds. This lack of genetic diversity puts the breed at risk for a variety of health conditions. Genetic variation refers to the differences between different individuals' DNA codes. Populations where there is high genetic diversity will have a wider range of different traits and will be more stable, in part because disease traits will be more diluted. In populations with low genetic variation, many individuals will have the same traits and will be more vulnerable to disease. The CB is the United Kingdom's oldest established horse breed and the only native warm-blood horse in the region. Used for recreational riding, driving, and equestrian competition, the CB is considered a critically endangered breed by the Livestock Conservancy. Because maintaining genetic diversity within the breed is important to securing the horses' future, Dr. Cothran and his team worked to gain comprehensive genetic information about the breed to develop more effective conservation and breeding strategies. In this study, published online on Septembr 20, 2019 in Diversity, researchers genotyped hair from 90 different CB horses and analyzed their data for certain genetic markers. These samples were then compared to each other, as well as to samples from other horse breeds to establish the genetic diversity within the breed and between other breeds.
MicroRNA-1 Alleviates Protein Accumulation by Controlling Autophagy; Finding May Be Key to New Therapeutic Approaches in Huntington's Disease and Parkinson's Disease
Research led by a Monash University (Australia) scientist has identified a highly conserved mechanism in worms and humans that controls the removal of toxic protein aggregates – hallmarks of neurodegenerative diseases. Insights from their study may provide a novel therapeutic approach for diseases such as Huntington's and Parkinson's. Associate Professor Roger Pocock, from the Monash Biomedicine Discovery Institute (BDI), and colleagues from the University of Cambridge led by Professor David Rubinsztein, found that microRNAs are important in controlling protein aggregates, proteins that have amassed due to a malfunction in the process of 'folding' that determines their shape. The scientists' findings were published online on December 9, 2019 in eLIFE. The open-access article is titled "Interferon-β-Induced miR-1 Alleviates Toxic Protein Accumulation by Controlling Autophagy." MicroRNAs, short strands of genetic material, are tiny but powerful molecules that regulate many different genes simultaneously. The scientists sought to identify particular microRNAs that are important for regulating protein aggregates and homed in on miR-1, which is found in low levels in patients with neurodegenerative diseases such as Parkinson's disease. "The sequence of miR-1 is 100 per cent conserved; it's the same sequence in the Caenorhabditis elegans worm as in humans even though they are separated by 600 million years of evolution," Associate Professor Pocock said. "We deleted miR-1 in the worm and looked at the effect in a preclinical model of Huntington's and found that when you don't have this microRNA there's more aggregation," he said. "This suggested miR-1 was important to remove Huntington's aggregates."
Scientists Find Way to Supercharge Protein Production; Discovery Promises to Aid Production of Protein-Based Drugs, Vaccines, Other Biomaterials
Medicines such as insulin for diabetes and clotting factors for hemophilia are hard to synthesize in the lab. Such drugs are based on therapeutic proteins, so scientists have engineered bacteria into tiny protein-making factories. But even with the help of bacteria or other cells, the process of producing proteins for medical or commercial applications is laborious and costly. Now, researchers at the Washington University School of Medicine in St. Louis have discovered a way to supercharge protein production up to a thousand-fold. The findings, published online on December 18, 2019 in Nature Communications, could help increase production and drive down costs of making certain protein-based drugs, vaccines, and diagnostics, as well as proteins used in the food, agriculture, biomaterials, bioenergy, and chemical industries. The open-access article is titled "A Short Translational Ramp Determines the Efficiency of Protein Synthesis." "The process of producing proteins for medical or commercial applications can be complex, expensive, and time-consuming," said Sergej Djuranovic, PhD, an Associate Professor of Cell Biology and Physiology and the study's senior author. "If you can make each bacterium produce 10 times as much protein, you only need one-tenth the volume of bacteria to get the job done, which would cut costs tremendously. This technique works with all kinds of proteins because it's a basic feature of the universal protein-synthesizing machinery." Proteins are built from chains of amino acids hundreds of links long. Dr. Djuranovic and first author Manasvi Verma, an undergraduate researcher in Dr. Djuranovic's lab, stumbled on the importance of the first few amino acids when an experiment for a different study failed to work as expected.
Scientists Discover New Mechanism in Childhood Kidney Cancer (Wilms' Tumor); Findings on Possible Role of ENL Chromatin Reader Protein May Point to New Treatment Approaches
As an embryo develops, its cells must learn what to do with the thousands of genes they've been equipped with. That's why each cell comes with a detailed gene-expression manual outlining exactly which genes should be switched on, to what extent, and when. To execute their respective manuals, the cells employ so-called chromatin reader proteins that identify which gene is up for expression. Now, a new study has found that a problem in this gene-regulatory process may cause normal cells to turn malignant and produce Wilms' tumor, the most common kidney cancer in children. The findings, which were published online on December 18, 2019, in Nature, open up new treatment possibilities for the disease, which is currently treated by surgery and chemotherapy. The article is titled "Impaired Cell Fate Through Gain-of-Function Mutations in a Chromatin Reader." The findings also raise intriguing questions about other cancer types. The researchers found that the implicated reader protein causes problems by acquiring a new property and being too active. "We have never seen this type of mechanism before," says Liling Wan, PhD, a former postdoctoral associate in the Rockefeller Univeersity lab of Dr. C. David Allis, and now an Assistant Professor at the University of Pennsylvania. "It raises the question whether this type of molecular mechanism is also hijacked in other cancer types." A few years ago, Dr. Wan discovered that a reader protein called ENL is involved in blood cancer leukemia by activating the cancer-causing genes. Her attention was turned to Wilms' tumor recently, when it was discovered that some people with Wilms' tumor carry mutations in the gene that codes for ENL.
Bio-Techne's Exosome Diagnostics Lab Receives Accreditation from College of American Pathologists (CAP); Recognition Builds on Recent Achievements of Company's ExoDx™ Prostate (IntelliScore) (EPI) Exosome-Based Liquid Biopsy Test
In a December17, 2019 press release, Bio-Techne Corporation (NASDAQ:TECH) announced that the Accreditation Committee of the College of American Pathologists (CAP) has awarded accreditation to its Exosome Diagnostics (ExosomeDx) laboratory based on results of a recent on-site inspection as part of the CAP's Accreditation Program. ExosomeDx was advised of this national recognition and congratulated for the excellence of services being provided. ExosomeDx is now one of more than 8,000 CAP-accredited facilities worldwide. "Receipt of CAP Accreditation represents another milestone in a banner year for our ExosomeDx platform and team," commented Chuck Kummeth, President and Chief Executive Officer of Bio-Techne. "This accreditation, combined with the CLIA, ISO 13485 and New York certifications already awarded to our laboratory, serve as a testament to the high-quality standards at our Waltham, Massachusetts facility. This recognition builds on the recent achievements of our ExoDx™ Prostate (IntelliScore) (EPI) test, including NCCN guideline inclusion, attaining FDA Breakthrough Device Designation, as well as the recently effective Medicare reimbursement determination issued by Medicare Administrative Contractor (MAC) National Government Services, Inc. All of these achievements position Bio-Techne to scale our EPI test and enable men to make more informed decisions on whether to proceed with an initial prostate biopsy." Johan Skog (https://www.pmwcintl.com/speaker/johan-skog_exosome-diagnostics_2020sv/), PhD, CSO of Exosome Diagnostics, willbe giving a presentation at the upcoming Precision Medicine World Conference (PMWC 2020) in Santa Clara, California (January 21-January 24) (https://www.pmwcintl.com/2020sv/).
Brain Protein (CD33) Regulates Microglia Cells and May Protect Against Alzheimer's
Tue, 12/17/2019 - 15:14 — bioquicknews
Research shows that white blood cells in the human brain are regulated by a protein called CD33 (image)--a finding with important implications in the fight against Alzheimer's disease, according to a new study by University of Alberta chemists. "Immune cells in the brain, called microglia, play a critical role in Alzheimer's disease," explained Matthew Macauley, PhD, Assistant Professor in the Department of Chemistry and co-author on the paper. "They can be harmful or protective. Swaying microglia from a harmful to protective state could be the key to treating the disease." Scientists have identified the CD33 protein as a factor that may decrease a person's likelihood of Alzheimer's disease. Less than 10 percent of the population have a version of CD33 that makes them less likely to get Alzheimer's disease. "The fact that CD33 is found on microglia suggests that immune cells can protect the brain from Alzheimer's disease under the right circumstances," said Abhishek Bhattacherjee, PhD, first author and postdoctoral fellow in the Macauley lab. Now, Dr. Macauley's research shows that the most common type of CD33 protein plays a crucial role in modulating the function of microglia."These findings set the stage for future testing of a causal relationship between CD33 and Alzheimer's Disease, as well as testing therapeutic strategies to sway microglia from harmful to protecting against the disease--by targeting CD33," said Dr. Macauley.
Extrachomosomal Circular DNA Drives Oncogenic Remodeling in Childhood Cancer; First Detailed Map of Circular DNA in Neuroblastoma Yields Unanticipated Insights
Cancer development is associated with the gradual accumulation of DNA defects over time. Thus, cancer is considered an age-related disease. But why do children develop cancer? An international team of researchers, led by scientists at Charité-Universitätsmedizin Berlin and the Memorial Sloan Kettering Cancer Center in New York, now reveal that mysterious rings of DNA known as extrachromosomal circular DNA can contribute to cancer development in children. Producing the first detailed map of circular DNA, the scientists have shed new unanticipated insights on long-standing questions in the field of cancer genetics. The work was published online on December 16, 2019 in Nature Genetics. The article is titled "Extrachromosomal Circular DNA Drives Oncogenic Genome Remodeling." Every year, nearly half a million people in Germany develop cancer. Approximately 2,100 cancer patients are children under the age of 18. The fact that the majority of cancers develop in old adults is due to the mechanisms contributing to cancer development. A range of exogenous factors, including tobacco smoke and radiation, can cause damage to cellular DNA. If this type of DNA damage is left to accumulate over many years, affected cells may lose control over cell division and growth. This results in cancer development. Children, however, are not old enough to be affected by this mechanism of cancer development. What, then, is the reason for childhood cancers? A team of researchers, led by Dr. Anton Henssen of Charité's Department of Pediatrics, Division of Oncology and Hematology and the Experimental and Clinical Research Center (ECRC,) an institution jointly operated by Charité and the Max Delbrück Center for Molecular Medicine (MDC), is now a significant step closer to finding an answer.
LAM's Liquid Biopsy Test of cfDNA Methylation Panel Enables Highly Sensitive and Specific Detection of the Most Common Liver Cancer (Hepatocellular Carcinoma)
Sun, 12/15/2019 - 20:01 — bioquicknews
Today we discuss the dissemination of DNA-methylation-based tests for non-invasive detection of cancer. BioQuick News recently sat down with Dhruvajyoti Roy (photo), PhD, who is the Director of Technology at the Laboratory for Advanced Medicine Inc. (LAM), an AI-driven healthcare company focused on commercializing early cancer detection tests from a simple blood draw, to learn about the company's technology and recent advances in the field of DNA methylation analysis. LAM developed a blood-based Liver Cancer Test, which can be used for early detection of liver cancer, as well as for monitoring disease recurrence. Dr. Roy had presented data from a validation study conducted by LAM on the ability of the assay to detect hepatocellular carcinoma (HCC), the most common form of liver cancer (more than 75% of all liver cancers, at The Liver Meeting® 2019 hosted by the American Association for the Study of Liver Diseases (AASLD), which was held in Boston from November 8-12, 2019. AASLD selected LAM's data for its poster presentation as a "Poster of Distinction." Posters of Distinction are classified as being in the top 10% of scored poster abstracts. (Dr. Roy was interviewed by BioQuick News editor Michael D. O'Neill and the text of the interview is provided below). QUESTION: Why did your group decide to focus on methylation status of cfDNA for your test? DR. ROY: Both genetic and epigenetic changes are known to be associated with the development of tumors. Over the last decade, analysis of cell-free DNA (cfDNA) from liquid biopsy samples, has emerged as a promising and potentially transformative, non-invasive diagnostic approach in oncology. cfDNA is composed of fragmented DNA released by cells into the circulation, typically as a result of cell death.
DNA Stress Sensed by Mitochondria Can Cause Them to Activate Innate Immune System, Including Interferon-Stimulated Genes (ISGs) That Act to Protect Nuclear DNA and This May Support Development of Resistance to DNA-Damaging Chemotherapy
Fri, 12/13/2019 - 22:22 — bioquicknews
Mitochondria, tiny structures present in most cells, are known for their energy-generating machinery. Now, Salk researchers have discovered a new function of mitochondria: they set off molecular alarms when cells are exposed to stress or chemicals that can damage DNA, such as chemotherapy. The results, published online in Nature Metabolism on December 9, 2019, could lead to new cancer treatments that prevent tumors from becoming resistant to chemotherapy. The article is titled "Mitochondrial DNA Stress Signalling Protects the Nuclear Genome." "Mitochondria are acting as a first line of defense in sensing DNA stress. The mitochondria tell the rest of the cell, 'Hey, I'm under attack, you better protect yourself,'" says Gerald Shadel, PhD, a Professor in Salk's Molecular and Cell Biology Laboratory and the Audrey Geisel Chair in Biomedical Science. Most of the DNA that a cell needs to function is found inside the cell's nucleus, packaged in chromosomes and inherited from both parents. But mitochondria each contain their own small circles of DNA (called mitochondrial DNA or mtDNA), passed only from a mother to her offspring. And most cells contain hundreds--or even thousands--of mitochondria. Dr. Shadel's lab group previously showed (in "Mitochondrial DNA Stress Primes the Antiviral Innate Immune Response" at https://www.nature.com/articles/nature14156) that cells respond to improperly packaged mtDNA similarly to how they would react to an invading virus--by releasing it from mitochondria and launching an immune response that beefs up the cell's defenses.
Why Giant Pandas Are Born So Tiny; Short Gestation Period May Be Cause
Born pink, blind, and helpless, giant pandas typically weigh about 100 grams at birth -- the equivalent of a stick of butter. Their mothers are 900 times more massive than that. This unusual size difference has left researchers puzzled for years. With a few exceptions among animals such as echidnas and kangaroos, no other mammal newborns are so tiny relative to their mothers. No one knows why, but a Duke University study of bones across 10 species of bears and other animals finds that some of the current theories don't hold up. Duke biology professor Kathleen Smith, PhD, and her former student Peishu Li published their findings this month in the Journal of Anatomy. The article was published online on December 2, 2019 and is titled "Comparative Skeletal Anatomy of Neonatal Ursids and the Extreme Altriciality of the Giant Panda." Baby panda skeletons are hard to come by, but the researchers were able to study the preserved remains of baby pandas born at the Smithsonian's National Zoo in Washington, D.C. The National Zoo's first panda couple, Ling-Ling and Hsing-Hsing, had five full-term cubs in the 1980s, but none of them survived long after birth. The researchers took micro-CT scans of two of those cubs, along with newborn grizzlies, sloth bears, polar bears, dogs, a fox, and other closely related animals from the Smithsonian National Museum of Natural History and the North Carolina State College of Veterinary Medicine. They used the scans to create 3-D digital models of each baby's bony interior at birth. As a baby animal grows and develops inside the womb, its bones and teeth do also. The researchers examined the degree of ossification, or how much the skeleton has formed by the time of birth.
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redpajama_set_name: RedPajamaCommonCrawl


text:
Galatea může znamenat:

 Galateia (latinsky Galatea) – v řecké mytologii dcera mořského boha Nérea, jedna z Néreoven
 Galateia (manželka Pygmaliona) – mytická oživlá socha bohyně Afrodity, manželka krále Pygmaliona
 Galatea (Massé) – dvouaktová komická opera francouzského skladatele Victora Massého
 Galatea (měsíc) – jedním z měsíců planety Neptun
 Galatea (planetka) – planetka nacházející se v hlavním pásu asteroidů

Externí odkazy

redpajama_set_name: RedPajamaWikipedia


Coming Soon - 'The Walking Dead' Magazine!
The Borenstein's story takes place in 1980 and follows the father of the present day Dr. Serizawa (played in the movie by Ken Watanabe,) while he reflects on his younger years of regretfully ignoring his role as a father in order to pursue the MUTO (Massive Unidentified Terrestrial Organism) a.k.a. the giant parasite Shinomura and the lizard-like Alpha predator Gojira a.k.a. Godzilla after the war until their seeming nuclear destruction at Bikini Atoll in the 1950s.
At the close of WWII, when the world was officially ushered into the nuclear age with the detonation of the atomic bomb at Hiroshima, the explosion awakens two monsters (Shinomura and Gojira) who've remained ancient enemies throughout Earth's history. 250 million years ago Earth had high levels of radiation, which the MUTO thrived on, but when an asteroid struck the Earth in an extinction level event 65 million years ago both creatures were driven underground due to dropping levels of radiation and laid dormant sustaining themselves near thermal vents until they sensed high levels of radiation which were released on the Earth's surface from the Hiroshima bomb.
The graphic novel bases its story in reality. General Douglas MacArthur, Hiroshima, Bikini Atoll and the U.S.S. Nautilus lend a bit of credibility to this non-realistic fiction piece. The plotline itself provides a good lead into the film without spoiling any key movie plot points. The read is easy and fast paced with a confidential Atomic Deployment Report from the unit known as MONARCH to button up the last page of the story revealing a frightening fact.
The last few pages of the graphic novel are devoted to the preliminarily pencil work from all four artists involved with the book. The final page sports the "Godzilla" film poster. Overall, it is a decent appetizer before seeing the movie. Be aware, the book showcases more of the human and MUTO element than Godzilla, who basically shows up to kick MUTO's tail.
Godzilla: Awakening is available at www.amazon.com, selected bookstores and at your local comic book shops.
The action/sci-fi/thriller "Godzilla" is scheduled for a Friday, May 16th release. The film stars Aaron Taylor-Johnson, Bryan Cranston, Elizabeth Olsen, Juliette Binoche, David Strathairn, Sally Hawkins, Ken Watanabe, Richard T. Jones, Brian Markinson, Patrick Sabongui and Akira Takarada. Max Borenstein, Frank Darabont and Drew Pearce wrote the screenplay based on the story by Dave Callaham and David S. Goyer. Gareth Edwards ("Monsters") directs.


This season we had 90 racers, race a min of one of the four events in the 2017 season. We had 4 different winners throughout the season and only one driver reach the finals twice this season. GLSSA paid out over $17,500 in round money, champion purses and prizes in the 2017 season.
Congrats to Dan Walcott on your 2017 GLSSA championship.
We look forward to seeing everyone in 2018.
Last edited by Charley Downing; 09-20-2017 at 02:34 PM.


CAD 28,964 ? EGP 371,759Program fees are indicative only. Speak to your IDP study counsellor to get up-to-date course prices.
USD 2,191 ? EGP 37,657Program fees are indicative only. Speak to your IDP study counsellor to get up-to-date course prices.


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Lawsuits Against Benicar Manufacturers Begin
In 2013, the FDA warned the general public about the dangers of Benicar and required its manufacturers to update the warning label. These dangers included developing a serous GI disorder, known as sprue-like enteropathy, which can lead to severe malnutrition, diarrhea, and dehydration. Now, injured patients are beginning to file lawsuits across the country, seeking to hold the negligent pharmaceutical manufacturer responsible for their suffering.
In 2013, the FDA began to investigate the link between Benicar and sprue-like enteropathy after a 2012 study by the Mayo Clinic exposed the connection. This led to the FDA forcing Benicar's manufacturer to update Benicar's labels warning patients of the serious gastrointestinal risks associated with using their drug.
Unfortunately, Benicar-induced sprue-like enteropathy may have affected more people than the manufacturers realize. Since sprue-like enteropathy caused by Benicar is similar to Celiac disease and gluten intolerance, many individuals may have been mistakenly diagnosed with Celiac disease or may be trying to control their GI symptoms with over-the-counter medications and/or a gluten-free diet.
The complications that can arise from Benicar-induced sprue-like enteropathy is staggering. Patients have reported years of diarrhea and malnutrition that has caused long-term intestinal damage in many. This can eventually lead to fatal GI complications if not treated quickly.
First Benicar Lawsuit Filed
The first Benicar lawsuit was filed earlier this year when a Texas man claimed that he developed severe gastrointestinal symptoms, including malnutrition and severe diarrhea after using Benicar. Due to his Benicar-induced illness, he was forced to spend over 100 days in the hospital and must now be fed through a feeding tube.
Several other plaintiffs have already come forward and filed the first of many Benicar lawsuits, alleging that the drug manufacturer failed to adequately warn the public of the dangers associated with the use of Benicar for hypertension. In addition, those lawsuits allege that the company knew of these risks and still promoted their drug without updating the labels.
This isn't the first time Benicar manufacturer Daiichi Sankyo has been in trouble with the FDA. In 2006, the FDA accused the company of deliberately and fraudulently marketing Benicar, by using false and unsubstantiated statements that failed to include important Benicar health risk information. In 2013, the FDA also cited the Benicar manufacturer for direct mail ads that made misleading and unsubstantiated claims to patients.


Booking fee to secure your flowers is £50, non-refundable, but deducted from final balance. Hire charges may apply for vases, pedestal stands and other items. Delivery/Set up cost vary per location.
For a Free consultation and more comprehensive quote that meets your specific requirements, please contact Vita.


how to convert the entire column field of table to dd/mm/yyyy format in microsoft sql server?
CONVERT VALUE MONEY TO WORDS IN SQL?
How to convert date to UTC format in Java?
How to convert current date to dd mm yyyy format in Java?
How to convert current date to mm dd yyyy format in Java?
How to convert string to date in java in yyyy-mm-dd format?


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Q: Prevent memory fragmentation Can anyone point me to a source or outline how the algorithm for the low-fragmentation heap works?

A: First decide which 'multiples' you want to use for the allocated memory chunks.  I typically use 8 bytes.
At startup of the application, make a vector where each element in the vector points to a 'pool' of memory chunks.  The first index in the vector will be for memory allocations of 8 bytes or less.  The second index in the vector will be for memory allocations from 9-16 bytes, and so on.
Within every pool, allocate memory in bigger chunks.  E.g. in the pool for allocations of 8 bytes (or less), don't allocate 8 bytes, but allocate N times 8 bytes.  Within the pool remember which parts are really allocated in the application and which parts are just waiting to be allocated.
When freeing memory, don't free it immediately, but keep some chunks ready for the next allocation of that size.
Only if you have a lot of subsequent free chunks, return the free memory to the operating system.
That's the basic idea.  The rest is implementing the pools (typically linked lists of chunks).
The difficult part is integrating the heap implementation into the application.

*

*If you are still using malloc/free, use #define's to redefine malloc and free

*If you use new/delete, define global new and delete operators

Also take a look at How to solve Memory Fragmentation, and my comment at Memory management in memory intensive application

A: From MSDN:

The LFH is not a separate heap. Instead, it is a policy that applications can enable for their heaps. When the LFH is enabled, the system allocates memory in certain predetermined sizes. When an application requests a memory allocation from a heap that has the LFH enabled, the system allocates the smallest block of memory that is large enough to contain the requested size.

This strategy is used by many memory managers, though the details can vary.

redpajama_set_name: RedPajamaStackExchange


text:
Q: Get list of interactive functions in Elisp/Emacs I have a bunch of my interactive functions with a prefix, say *zb/" (e.g. "zb/create-temp-buffer"). I am a bit tired every time to type in M-x interaction this prefix of a command I like to run.
To automate this I'd like to retrieve a list of all my interactive functions and show them through ido-completing-read (btw, possibly there are other alternative and modern ways to create input with predefined items and autocompletion?). But I did not manage to find how to retrieve a such list. Could you please give me a cue how to achieve this?
List of all available interactive functions will be enough; to filter is not an issue.
Thanks.

A: You can use this function for selection
(defun eab/select-zb/ ()
  (interactive)
  (call-interactively
   (intern
    (ido-completing-read "M-x zb/"
             (mapcar 'symbol-name (apropos-internal "^zb/"))))))

A: Maybe give Smex a try?

Smex is a M-x enhancement for Emacs. Built on top of Ido, it provides a convenient interface to your recently and most frequently used commands. And to all the other commands, too.

A: You say "possibly there are other alternative and modern ways to create input with predefined items and autocompletion?".

*

*Use Icicles and just bind icicle-must-match-regexp:

    (defun zb/ ()
      (interactive)
      (let ((icicle-must-match-regexp  "^zb/"))
        (call-interactively (intern (completing-read "zb/ command: " obarray 'commandp t)))))

*

*You can also do it with vanilla Emacs and without Ido:

    (defun zb/ ()
      (interactive)
      (call-interactively
        (intern (completing-read
                 "zb/ command: "
                 obarray
                 (lambda (cmd)
                   (and (commandp cmd)  (string-match-p "^zb/" (symbol-name cmd))))
                 t))))

Or do as @artscan suggested: use apropos-internal to match the regexp.  IOW, either let completing-read do the matching or match first using apropos-internal.  You can pass the commandp predicate to apropos-internal as well.


text:
Franco Panizza, né le  à Campodenno, est un homme politique italien, membre du Parti autonomiste tridentin et tyrolien.

Biographie

Secrétaire du Parti autonomiste tridentin et tyrolien, Franco Panizza est élu sénateur dans le collège uninominal de Trente, en coalition avec le Parti démocrate et la Südtiroler Volkspartei, le .

Notes et références

Lien externe

Naissance dans la province de Trente
Personnalité politique italienne du XXIe siècle
Sénateur de la dix-septième législature de la République italienne
Naissance en décembre 1959
Personnalité du Parti autonomiste tridentin et tyrolien


text:
Deep Insanity: The Lost Child (Dub) Downloads
Ms.Emma mai 24, 2022 mai 24, 2022
If you are looking for Deep Insanity: The Lost Child (Dub) downloads, you have come to the right place! You can watch this anime episode online for free, and you can share it with friends and family! We are constantly updating our website with the latest episodes of your favorite anime series, so make sure to visit us regularly to watch the latest episodes. Deep Insanity: The Lost Child is a horror anime series set in a mental hospital. The premise of the story is that the children are possessed by a mad doctor who is responsible for the child's death.
Anime Deep Insanity: The Lost Child
If you're looking for a site where you can watch Deep Insanity: The Lost Child ep 1, you've come to the right place. Gogoanime has a great library of anime that you can watch online or download for offline viewing. Not only can you watch Deep Insanity: The Lost Child online for free, but you can also share it with your friends and family on Facebook or Twitter. You can also subscribe to Gogoanime on Facebook or Twitter to stay updated on new releases.
Anime Deep Insanity: The Lost Child (Dub)
Anime Deep Insanity: 'The Lost Child' is a crossover fantasy manga from Square Enix that follows a boy immune to Randolph syndrome who journeys into the « Asylum ». The manga's main character, Woo Inominetas, is voiced by Yuichiro Umehara. Deep Insanity: The Lost Child (also dubbed) is one of the best anime adaptations of the series to date.
Anime Deep Insanity: THE LOST CHILD is an English-language dub of the popular Japanese video game series of the same name. It is directed by Shin Oonuma and is part of Square Enix's media project. The anime is currently being dubbed by Funimation Entertainment. Deep Insanity: The Lost Child will premiere on the FunimationNow streaming service on December 14, 2021.
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text:
Enterprising Youth
Meet the Brain Behind 'Emerging Change Academy'
yomi
Tade Ayodele is an innovative entrepreneur, leader and motivational speaker. He is the President of Emerging Change Academy (ECA), a Youth development outfit based in Nigeria.
Tade holds a Bachelor's degree in Aquaculture and Fisheries Management, Masters Degree in Fisheries & Hydrobiology; and he is currently studying for a PhD.
During his undergraduate studies, just before founding ECA (formerly MANABEP) in 2004, he was a member of the Youth Arm of International Association of Lions Clubs (Leo Club) where he served as President of his branch in 2005. He was privileged to also serve on the District Board as Region Director, Vice District President and finally District President of the same International Organization at different times.
He served as the President of his department where he contributed and carried out projects that encouraged the growth of young people. This gave him the opportunity of serving as an ex-officio member of the Ogun State Branch of the Fisheries Society of Nigeria (FISON). He also served as the Founder and Coordinator of the Trumpeters Speakers Club, the first and only Speakers Group in the University of Agriculture, Abeokuta (UNAAB).
Tade lectures at the Federal College of Agriculture, Ishiagu where he teaches Fisheries Technology.
Through ECA, Tade has conducted leadership, career and character development trainings that focus more on young people. His main interest is in Public Speaking has shown himself to be an ebullient Speaker.
Olumide Ajayi: I.T Genius with deep passion for younger generation
My motivation is to solve problems and create new opportunities – Odebiyi
Chioma Ukonu: Resilient and innovative entrepreneur
Ooni Hosts Youths, Women Empowerment Summit
Olumide Adeleye: The Brain Behind Twim Art Institute
Tags: Emerging Change Academy, Tade Ayodele
Pension System in Nigeria Lacks Care and Respect for Senior Citizens- Ajibade
WINNING THE ODD WAY. "You've got to be odd to be number one." ― Dr. Seuss


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Add Perfect Fit Side-Loading sleeves for maximum card protection. Perfect Fit Sideloader sleeves protect the tops and bottoms of your cards for maximum card security and fit snugly inside all Standard Size Dragon Shields.


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text:
package org.spongepowered.despector.decompiler.method.graph.create;

import org.spongepowered.despector.ast.Locals;
import org.spongepowered.despector.ast.Locals.LocalInstance;
import org.spongepowered.despector.decompiler.ir.Insn;
import org.spongepowered.despector.decompiler.ir.InsnBlock;
import org.spongepowered.despector.decompiler.method.PartialMethod;
import org.spongepowered.despector.decompiler.method.PartialMethod.TryCatchRegion;
import org.spongepowered.despector.decompiler.method.graph.GraphProducerStep;
import org.spongepowered.despector.decompiler.method.graph.data.TryCatchMarkerType;
import org.spongepowered.despector.decompiler.method.graph.data.opcode.OpcodeBlock;
import org.spongepowered.despector.decompiler.method.graph.data.opcode.TryCatchMarkerOpcodeBlock;

import java.util.List;
import java.util.Set;

/**
 * A graph producer that creates opcode blocks for try-catch statements. It
 * inserts also inserts marker blocks to denote the start and end of try blocks
 * and the start of catch blocks.
 */
public class TryCatchGraphProducerStep implements GraphProducerStep {

    @Override
    public void collectBreakpoints(PartialMethod partial, Set<Integer> break_points) {
        InsnBlock instructions = partial.getOpcodes();
        Locals locals = partial.getLocals();

        for (TryCatchRegion tc : partial.getOpcodes().getCatchRegions()) {
            if (tc.getStart() > 0) {
                break_points.add(tc.getStart() - 1);
            }
            break_points.add(tc.getEnd());
            break_points.add(tc.getCatch());

            LocalInstance local = null;
            for (int i = tc.getCatch() + 1; i < instructions.size(); i++) {
                local = locals.findLocal(i, "L" + tc.getException() + ";");
                if (local == null) {
                    local = locals.findLocal(i, "Ljava/lang/RuntimeException;");
                    if (local == null) {
                        local = locals.findLocal(i, "Ljava/lang/Exception;");
                    }
                }
                if (local != null) {
                    break;
                }
            }
            if (local != null && local.getEnd() < instructions.size() - 1) {
                break_points.add(local.getEnd());
            }
        }
    }

    @Override
    public void formEdges(PartialMethod partial, List<Integer> sorted_break_points, List<OpcodeBlock> block_list) {
        for (int i = partial.getOpcodes().getCatchRegions().size() - 1; i >= 0; i--) {
            TryCatchRegion tc = partial.getOpcodes().getCatchRegions().get(i);
            TryCatchMarkerOpcodeBlock start_marker = new TryCatchMarkerOpcodeBlock(TryCatchMarkerType.START, tc);
            TryCatchMarkerOpcodeBlock end_marker = new TryCatchMarkerOpcodeBlock(TryCatchMarkerType.END, tc);
            TryCatchMarkerOpcodeBlock handler_marker = new TryCatchMarkerOpcodeBlock(TryCatchMarkerType.CATCH, tc);
            start_marker.setEndMarker(end_marker);
            end_marker.setStartMarker(start_marker);
            handler_marker.setStartMarker(start_marker);
            handler_marker.setEndMarker(end_marker);
            OpcodeBlock start;
            if (tc.getStart() == 0) {
                start = GraphProducerStep.find(block_list, 0);
            } else {
                start = GraphProducerStep.find(block_list, tc.getStart());
            }
            OpcodeBlock end = block_list.get(block_list.indexOf(GraphProducerStep.find(block_list, tc.getEnd())));
            OpcodeBlock handler = GraphProducerStep.find(block_list, tc.getCatch());
            if (end.getEnd() == tc.getEnd() && end.getLast().getOpcode() == Insn.ARETURN) {
                end = block_list.get(block_list.indexOf(GraphProducerStep.find(block_list, tc.getEnd() + 1)));
            }
            block_list.add(block_list.indexOf(start), start_marker);
            block_list.add(block_list.indexOf(end), end_marker);
            block_list.add(block_list.indexOf(handler), handler_marker);
        }
    }

}

redpajama_set_name: RedPajamaGithub


Paintings, drawings, words. All of it. I'm in love with Herikita's art. It speaks truths in soft colors and is quite often made-up of angled homes and rooftops, pets and insects, women and men, all of whom are sharing their awkward feelings and I just want more and more of it.
Her bio alone was enough to make me smile. Here's a small bit of my favorite part, "I work at midnight like Cinderella's mice, almost always, when everyone is sleeping and something pops up in my mind.."
It's such a great visual.


text:
Showbiz Muse
Muscle Museum
Fillip
Unintended
Hate This and I'll Love You
Spiral Static (Bonus Track)
℗ 1999 A&E Records Limited
King Pig III , 05/22/2015
Waaaay too underrated
This album deserves more!!
1 Sunburn- beautiful! Piano and haunting rock chorus 10/10
2 Muscle Museum- amazing rocker with a killer bass 10/10
3. Fillip- can't help but dance. Just wish the chorus ending were a little cleaner 10/10
4. Falling Down- Slow song, fairly decent 9/10
5. Cave- ok this is amazing just buy it 10/10
6. Showbiz- extremely haunting dramatic song that I love to death just buy it already ! 10/10
7. Unintended- another slower more tenderhearted song. Pretty good. 10/10
8. Uno- probably the only track I don't really like. The chorus is just so... Bland. It's the same note over and over and is just not that good... 3/10
9. Sober- It took a long time for the words to stick and it's sounds really 90's but it's really good 9/10
10. Escape- Chris says he though it was underrated and it is. Perfect. 10/10
11. Overdue- kind of forgettable but not bad 7/10
12. Hate this and I'll love you- Kind of exact same as Overdue
Overall 9/10
Franki one o one , 03/18/2018
I think this album is one of their best, but one of their most underrated albums. It has classic songs that any Muse fan can remember, such as "Sunburn," "Uno," and "Muscle Museum" (which is one of my favorite songs.) But it has some of my all time favorite songs buy them, like "Muscle Museum" which stands out far more unique than other songs on the album. "Fillip," which to be honest, is one of my favorite Muse songs even though not many people are familiar with it. "Sober," which has a squealing guitar solo after the second chorus which gives this song so much more taste. Not only to the song, but to the album. And one of my favorites is one of their most underrated songs in their category, "Spiral Static," the one song I truly love but has never been played live or been recognized for its full potential. The bass, guitar, drums, and vocals work so well, and it sounds so awesome. 10/10, flawless album.
Webbbbbbbbbb , 01/21/2016
If you're a Muse fan, get it.
For Muse fans, it's a great album. For others, you should start somewhere else like Black Holes & Revelations or Absolution. As most of you may know, many people tend to hate this album for it's technical similarities to Radiohead. Particularly the album OK Computer (Though I would say that this sound a lot more like The Bends). And I won't deny the similarities between the two. However, there aren't any songs on this album that I would say "rip off" any Radiohead song. And OK Computer is one of the most influential albums in Alternative music so you can't expect it to not inspire a few bands in their early days. Overall, the album is good. There are some hidden gems on this album that make it very underrated.
More By Muse
The 2nd Law (Deluxe Version)
The 2nd Law
Simulation Theory (Deluxe)
Black Holes and Revelations
Hullabaloo Soundtrack
Sleeping with Ghosts
Our Earthly Pleasures
Maxïmo Park
Ghinzu


The Ledges of St. George or Coral Canyon, what's your preference? Soaking in the inspirational views of Southern Utah's Snow Canyon or enjoying a quiet cul-de-sac nestled in the Highland Park subdivision of Coral Canyon?
It's Saturday, May 13, 2017, and so far this morning, seven Realtors have announced their intention to hold an Open House.
Short and sweet, today's southern Utah's open house inventory offers an abbreviated look at just some of the housing options available in the greater St. George area.
It's Saturday, March 24, 2017 and there are currently four open houses scheduled in the greater St. George area, according to the Southern Utah Open House Directory.
While there remains a 40% chance of rain for today, visitors and locals alike will be out and about at the Tuacahn Saturday Market and heading out to Hurricane. Though some will be in search of shopping opportunities, others will be looking to enjoy the world-class mountain bike terrain at the local mountain bike Festival. Regardless of whether your here for fun in the sun or simply for the shopping, you have discovered the jewel of the American Southwest – St. George, Utah.
From the beautiful Snow Canyon landscapes surrounding the Reserve at Entrada, to breathtaking vistas that embrace The Ledges of St. George, today's Southern Utah Open House Directory indicates our four open houses are scattered throughout Washington County.
From the breathtaking vistas of Augustus Point to the equestrian friendly meadows of Washington Fields, the Southern Utah Open House Directory has nine listings currently scheduled as an Open House for today.
It's Saturday, January 14, 2017. While the St. George Area Economic Summit exposed the variables that will provide homeowners appreciation in the coming year – population influx, lack of inventory, and low unemployment rates – the WCBR FlexMLS system indicates there are only 589 active single-family residential listings between $104,000 and $3,995,000.
Just off the Snow Canyon Parkway, near Entrada golf course and the Canyons Baseball complex, is the yet to be built out subdivision of Augustus Point. Providing those with vision and drive an opportunity to build their dream home, Augustus Point is located between downtown St. George and the city of Ivins. Next to the beautiful community of Paradise Canyon, Augustus Point enjoys breathtaking views and a central location. Close to shopping, health care, and golf, Augustus Point provides an elevated lifestyle at a down-to-earth price.
Southern Utah Open House Directory: The Palisades to Stucki Farms, It's That Time!
From the Palisades near Snow Canyon to Stucki Farms in Washington Fields, Realtors around southern Utah are preparing for their Saturday morning Open House. As of 6 AM, there are currently nine real estate listings scheduled as "Open" according to the Washington County Board of Realtors FlexMLS system.
It's Saturday, December 10, 2016, and with just 14 shopping days left before Christmas, Southern Utah's real estate market remains incredibly healthy and focused on future growth and potential inventory issues. Jumping 11% on a year-over-year basis, just over 4200 single-family residential real estate listings have successfully closed escrow in Washington County from January 1 to November 30. With the average real estate listing selling in just under three months for just under $271,000, Vardell Curtis believes there is a looming inventory issue on the horizon, according to The Spectrum.
And with that said, today's Southern Utah Open House Directory has three available properties between $239,000 and $259,500. From the beautiful Bloomington Country Club area of St. George – a neighborhood known for its mature trees and larger lots – to the equestrian friendly neighborhood of Stucki Farms, today's St. George open house inventory offers something for everyone.
Embraced by the Crimson Cliffs of the Snow Canyon corridor and surrounded by some of Southern Utah's most desirable guard gated communities, The Palisades PUD provide its resident's world-class amenities at down-to-earth prices. Providing oversized lots, inspired views, and an active lifestyle, residents of The Palisades will enjoy a lifetime of breathtaking vistas of the surrounding red rock plateaus, stunning southwestern Sunsets and its close proximity to St. George's Tuacahn Amphitheater. Also conveniently close to some of Southern Utah's best walking, hiking, and biking paths, this master planned subdivision is just a few short minutes from downtown St. George.
St. George, Utah – Labor Day is thankfully over, white is no longer acceptable to wear until Next Memorial Day, and there are currently 9 Open Houses scheduled on the WCBR (Washington County Board of Realtors) MLS (multiple listing system) for today.
As the Hurricane City Council hammers out their ugly restrictions on vacation rentals and St. George's IHC receives national kudos for their groundbreaking cancer program, today's nine Open Houses are scheduled in the subdivisions of Entrada, Kayenta, Bloomington Country Club, Mulberry Estates and the 55+ community of Crystal Lake Town Homes.
St. George, Utah – it's July 16, 2016, today there are ten real estate listings scheduled for today's Southern Utah Open House Directory.
As Turkey rejects its ugly coup d'état, France comes to grips with its Bastille Day massacre, and "The Donald" get's ready whip up his own special brand of fear and loathing in Ohio this week, life in St. George remains relatively quiet, predictable and drama free.
After a quick seven days of vacationing in Pacific Grove, Carmel, and Big Sur, California, it's time for me to get back to work and disseminate the information today's Southern Utah home buyers so desperately seek; creating the only MLS driven Open House Directory for all of Southern Utah.
Directions: Take Sun River Parkway. Turn right on Country Club, right on Bluegrass, left on Kiva Hill and left onto Datura Hill. Home is on the right.
Comments: This is a 1,323 sf Aspenglow model with 2 bedrooms, 2 bathrooms and a 2 car garage. It sits above the homes behind it, affording some views from the back patio. List price is $215,000.
Directions: From Sun River Parkway, take the first Right, which is Pioneer Road. Go Left on Bluegrass Way, Right on Magellan Dr & Left on Cantamar. Home is 2nd on the Left & backs up to Bluegrass Way.
Comments: This is a 1,311 sf Sandstone II model with 2 bedrooms, 2 bathrooms, and a 2 car garage. This home features a full-sized master suite with a large master bathroom and closet. List price is $212,000.
Directions: From Main St, take University west over the freeway and turn left on 1650 W. (map may say 1600 W). Turn right on Juniper Dr., then left on S. Casa Loma. Property is the second house on the left.
Comments: Come and check out the views from this home!!!
Directions: Take exit 4 Bloomington, follow round about to Pioneer Pkwy. Turn right Man of War. Turn left on Bloomington Dr and follow around to Shivwits. Turn left on Shivwits to end, turn right on Paiute.
Directions: Stone Cliff parkway(Go through round about) Which becomes Stone Cliff Point Dr. Turn left on View Point Dr. Home is on the Left.
Comments: Stop by and enjoy the beauty and views, views, views.
Directions: Take Sun River PKWY, left on Big River, Left on Spirit Walker Dr.
Comments: This is a 2,868 sf grand Reflections model with 2 master bedrooms, a casita, a den, a formal living/dining room, a family room, and a 3 car garage. List price is $384,000, making it the best value and price per square foot in Sun River.
Directions: Take Sun River Parkway. Turn left on Ironwood and then left on Sunstar. Home is a couple of blocks down on the left.
Comments: Charming 1,782 sf Windsong model featuring open great room w/ built-in entertainment center, bookshelves & fireplace, upgraded lighting & fan. Double ovens, expanded laundry room w/extra cabinets & utility sink, bay windows, jetted tub, epoxy floor in garage, expanded patio w/louvered blinds and sun shades & lovely views of the golf course. 2 bed, 2 bath, den, 3 car garage. Purchase price is $428,000.
Directions: Take Sun River Parkway. Turn Left on Ironwood. Home is on the left.
Comments: This is a lovely 1,717 sf Windsong model on the golf course. The unique shape of the terrain in the back allows for both privacy and views! Hot Tub and built-in BBQ included! 2 bedrooms, 2 bathrooms, a den, plus a 2 car garage. Priced at $389,000.


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The supports utilize a SPECIAL KNITTING COMPRESSION TECHNOLOGY to provide support to the ankle region. The ADJUSTABLE compression also helps to improve circulation and reduce inflammation. It is of course safe, effective, and easy to use. It can be worn all day and night for long-lasting relief. Whether suffering from an ankle injury but still need flexibility, or just from everyday use, this ankle sleeve is ideal for everyone. It is breathable, comfortable and light weight, it allows to be worn well in a shoe.


Kelley Foxx is the husband of Cook County State's Attorney, Kim Foxx.
Kelley's wife became the first African-American woman to serve as Cook County state's attorney in Chicago, when she assumed office in 2016. She previously served as Chief of Staff for the Cook County Board President.
Kim was also an Assistant State's Attorney for 12 years. The Chicago native graduated from Southern Illinois University, where she earned a B.A. in Political Science and a J.D. from the SIU School of Law.
She has been married to husband Kelley Foxx, for several years. Check him out on his top facts below.
Kelley Foxx met future wife Kim while attending SIU in 1996. The two became husband and wife in 2001. That means they have been married for the last 18-years.
The two have welcomed two children together, teenage daughters Kendall and Kai.
He holds a B.A., Radio & Television from Southern Illinois University, Carbondale; and an MBA from the University of Phoenix.
According to ChicagoMag, the Kelley and Kim Foxx, recently assumed guardianship of two sisters, one of whom is a close friend of their younger daughter. The girls are Sydney and Savannah Abajian.


text:
Home/News & Gossips/OMG: Akshay Kumar holds a sanitary napkin in Padman Poster
OMG: Akshay Kumar holds a sanitary napkin in Padman Poster
Ganesh Send an email December 16, 2017Last Updated: December 18, 2017
Padman Movie
The superstar of B Town, Akshay Kumar seems to be creating a great curiosity among the audience. Thanks to his cool marketing strategy methods for his next film called Padman. The actor has released a number of out of box and superb buzz posters in the media for this film. We now hear that the actor has embarked with a new poster in order to raise the craze and out or box excitement. In the latest still, we have seen him holding a sanitary pad in his hand and that seems ready to give him a speech on it as well. The B Town Khiladi now is seen with a sanitary napkin at the backdrop of New York City.
This simply means that he is now keen on sharing his experience and journey in the beast country called the USA. The actor has posted a cool poster on the Twitter account wherein he has captioned PadManTalks and he then went on saying that with this the women can get extra life. The film is releasing next month on the even of republic day. This is not the first time when we see him working on similar social projects, well, he has earlier been the part of similar movies be it Jolly LLB 2 or some other movie, he has been the part of the film in a big way.
Talking about the same in the earlier interviews, he was seen talking in a leading daily, when Akshay was asked about his film he said it is a film talking about menstruation and said that it is about getting being bold, but at the same time talking about the taboos and breaking them. He said he understands the problems of woman as he has lived all these years with his wife. The film Padman is directed by R. Balki, which features Sonam Kapoor and Radhika Apte in the key roles. The film is set to hit the theatres on January 26, 2018, which will be clashing with Sidharth Malhotra and Manoj Bajpayee starrer film called Aiyaary at the box office.
What Kiran Rao Has to Say about Zaira Wasim's Molestation Case
Catch Padman Trailer with Akshay Seen another Indian Superhero


Packed with features and truly a pleasure to drive! Acura prioritized fit and finish as evidenced by: a power seat, turn signal indicator mirrors, and a blind spot monitoring system. Smooth gearshifts are achieved thanks to the 3.5 liter 6 cylinder engine, and for added security, dynamic Stability Control supplements the drivetrain.


text:
package org.interonet.mercury.tool;

public interface MercuryTimerCallBack {
    void run();
}


While Axis' Q3517-LVE tested well, it is one of Axis' most expensive dome cameras, over $1,000 USD. Because of this, members asked us how it compares to Axis' "mid range" P3227-LVE, their P series 5MP option.
How do full light (~300 lux) details compare?
How do nighttime (~0.01 lux) details compare with IR illumination on?
How evenly does each camera illuminate the field of view?
Do both cameras meet specified IR range?
How does color low light (~2 lux) performance compare?
How does wide dynamic range performance compare?
How do day and night smart codec bitrates compare?
*********' *****-*** ****** ****, ** ** *** of ****' **** ********* dome *******, **** $*,*** USD. ******* ** ****,******* ******* *** ** ******** to ****' "*** *****"*****-***, ***** * ****** 5MP ******.
*** ** **** ***** (~300 ***) ******* *******?
*** ** ********* (~*.** lux) ******* ******* **** IR ************ **?
*** ****** **** **** camera ********** *** ***** of ****?
** **** ******* **** specified ** *****?
*** **** ***** *** light (~* ***) *********** compare?
*** **** **** ******* range *********** *******?
*** ** *** *** night ***** ***** ******** compare?
*** *** **** ******* inside.
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What to eat? What to eat?....Something that crosses our mind on any given day. Tater tot pizza casserole is not only delicious, but perfectly fills the title of the ultimate comfort dish. Combining two favorite flavors into one amazing meal! Try it today, you won't be sorry!
Heat a large skillet over medium high heat. Add ground beef, sausage and bacon. Cook for 7 minutes. Add in mushrooms, onions, garlic and green pepper. Cook an additional 5 to 7 minutes, or until meat is cooked and veggies are softened. Stir in pizza sauce.
Preheat oven to 400F. Spray a large casserole dish with cooking spray. Spread pizza mixture evenly on the bottom. Cover completely with Tater Tots.
Bake for 40 minutes. Remove from oven and sprinkle with mozzarella cheese and pepperoni. Bake an additional 5 minutes, or until cheese is melted. Remove from oven and top with Italian seasoning. Serve hot.


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Archive for the 'mosquito-borne diseases' Category
State of emergency in Marshall Islands as dengue outbreak spirals
Posted by feww on October 29, 2011
Warmer, wetter weather boosting spread of mosquito-borne infectious diseases
Marshall Islands declare state of emergency as dengue fever outbreak spreads
Health officials in Majuro, Marshall Islands have declared a state of emergency as the outbreak of dengue fever cases doubles in two days.
Disaster Calendar 2011 – October 29
[October 29, 2011] Mass die-offs resulting from human impact and the planetary response to the anthropogenic assault could occur by early 2016. SYMBOLIC COUNTDOWN: 1,600 Days Left to the 'Worst Day' in Human History
Majuro, Marshall Islands. The first case of dengue fever, an infectious tropical disease, was diagnosed at Majuro Hospital last week. The reported cases have now spiraled to at least 63, doubling in the past two days.
Dengue fever is a virus-caused disease that is spread by mosquitoes.
The disease's flu-like symptoms include fatigue, fever, headache, nausea, swollen lymph nodes, vomiting, muscle aches, joint pains and a skin rash that resembles measles.
The infection can develops into the life-threatening dengue hemorrhagic fever, or result in dengue shock syndrome, leading to dangerously low blood pressure.
Dengue hemorrhagic fever (DHF) is a severe, potentially deadly infection spread by certain species of mosquitoes (Aedes aegypti and Aedes albopictus).
Symptoms of DHF are similar to to those of dengue fever, but after several days the symptoms are followed by a shock -like state.
Shock could cause death.
DHF has killed hundreds of people in Pakistan, India, China and other SE Asian countries this year so far.
Increases in temperature, precipitation, and humidity are exponentially boosting vector abundance and disease incidences throughout the world.
Lahore, Pakistan. At least 31,036 cases of dengue fever have been recorded in Lahore alone, a report said.
Pakistan's Health Department has "confirmed four deaths, including two from Lahore, due to Dengue Hemorrhagic Fever (DHF) during the last 24 hours, which brought total figure of deaths to 290 in Punjab and 253 in Lahore."
"The dengue fever claimed four more lives on Friday, which brought the death count to 317 in the provincial metropolis." Said the report.
USA. Mosquito-Borne Dengue Fever Threat Spreading in the Americas: Dengue Fever Vulnerability in the United States
Dengue vulnerability in the United States. Among the social and environmental factors that increase community vulnerability to dengue and other infectious diseases are poor municipal infrastructure and frequent storm damage to homes. Red areas of the map show U.S. counties that have reported the presence of one or both of the mosquito species (Aedes aegypti and Aedes albopictus) that can potentially transmit dengue fever; blue regions highlight the area encompassing most of the positive counties. Numbers of suspected cases of dengue infection reported from 1995–2005, inclusive, are shown below each state name. Reported counts of suspected dengue fever cases are also included for the six Mexican states that border the United States. Source: NRDC
Global Impact. Dengue fever and its complications cause about 100 million infections, resulting in 500,000 hospitalizations and 22,000 deaths annually in over 100 countries.
Dengue incidences have multiplied by 30-fold in less than 5 decades globally.
The worst hit areas are India, Pakistan, South America, Central America, the Caribbean, Southeast Asia and Africa.
Currently, about 2.5 people are at risk of for dengue because of climate change.
"Epidemic outbreaks during 2007 in Brazil, Mexico, Honduras, Paraguay, Costa Rica, Bolivia, and Guyana affected hundreds of thousands," NRDC report said.
About 56 percent of Americans (175 million people, as of posting) live in counties where one or both of the mosquito species that can transmit dengue fever have become established.
Dengue fever toll climbs to 162
Measles Outbreaks Continue in Canada, New Zealand, Europe
The First Wave of World's Collapsing Cities (EDRO Forecast)
2011 Much More Disastrous: FIRE-EARTH Forecast
Global Disasters in 2011 Could Impact 1/3 to 1/2 of the Human Population (FIRE-EARTH Forecast)
Back to the Primordial Future
Mass Die-offs (FIRE-EARTH Forecast)
Posted in global delta flooding, global deluge, global disasters, mosquito-borne diseases | Tagged: Aedes aegypti, Aedes albopictus, Dengue fever, dengue hemorrhagic fever, dengue shock syndrome, Dengue vulnerability in the United States, Marshall Islands, Marshall Islands state of emergency, spread of mosquito-borne infectious diseases | Leave a Comment »


text:
Q: Nginx - after enable http2 doesn't cache js and css, (Chrome) Before I enable http2 on nginx, I can have js and css file cached, but after that, I found the cache doesn't work on those 2 types of files.
Is that expected?
Here is my Nginx configuration:
#ssl
listen 443 ssl http2 default_server;

ssl_certificate /opt/server.crt;
ssl_certificate_key /opt/server.key;

# Statistic Files
location ~ ^/(images/|img/|javascript/|js/|css/|stylesheets/|flash/|media/|static/|robots.txt|humans.txt|favicon.ico|uploadFiles/|template/) {
  root /opt/nodejsblog/public;
  access_log off;
  expires 1y;
  add_header Cache-Control public;
}

# Proxy to backend load balance servers, connect to upstream
location / {
  proxy_redirect off;
  proxy_set_header   X-Real-IP    $remote_addr;
  proxy_set_header   X-Forwarded-For  $proxy_add_x_forwarded_for;
  proxy_set_header   X-Forwarded-Proto    $scheme;
  proxy_set_header   Host $http_host;
  proxy_set_header   X-NginX-Proxy    true;
  proxy_set_header   Connection   "";
  proxy_http_version  1.1;
  proxy_cache one;
  proxy_cache_key sfs$request_uri$scheme;
  proxy_pass  http://my_node_site; # refer to the ubove node site

}

What's wrong with my settings?
PS: I found on Firefox 38.x, it works fine, the issue only exist on Chrome 46.x.
On chrome I didn't disable cache with developer tool(font file, and images has been cached correctly.)


Gold Spins Casino is not available in United States!
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With new slots being added each month, this number has steadily grown since the site first began operating and now includes recently released titles like Aloha! Cluster Pays, Guns N' Roses and A Dragon's Story. While that's great for players who want to try brand new games fresh from the developer's suite, those with more established slot preferences won't be disappointed either.
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Research Roundup: 6 Takeaways on the Goodness of Gratitude
More and more scholars are studying the practice of giving thanks. Here's what they have to say.
Stefani McDade| November 23, 2021
Image: Oksana Aksenova / Getty Images
"Feeling Gratitude Is Associated with Better Well-Being Across the Life Span: A Daily Diary Study During the COVID-19 Outbreak"
Da Jiang, Journals of Gerontology: Series B, Psychological Sciences and Social Sciences, December 2020
"Numerous studies have shown that gratitude can improve the mental health of people facing stressful events. However, most studies in this area have been based on laboratory experiments and retrospective surveys, rather than actual situations in which people are experiencing stress."
"This study attempted to fill these gaps by examining the benefits of feeling gratitude every day during the COVID-19 outbreak. … These findings demonstrate the benefits of gratitude in a naturalistic situation that induced stress and anxiety."
Our read: These researchers studied the simple power of gratitude to improve individuals' well-being during a global pandemic. In response to a number of other studies showing the value of keeping a "gratitude journal" during traumatic seasons of life, each participant was asked to track daily levels of gratitude in a diary. For Christians, the spiritual benefits of writing down our prayers of thanksgiving to God, especially in hard times, should be self-evident!
"Give Thanks in All Circumstances? Gratitude Toward God and Health in Later Life After Major Life Stressors"
Laura Upenieks and Joanne Ford-Robertson, Research on Aging, August 2021
"Gratitude is foundational to well-being throughout the life course, and an emerging body of work suggests that older adults may be more inclined to attribute gratitude to a non-human target (God)."
"Results suggest that gratitude toward God tends to predict better age-comparative and global self-rated physical health in the aftermath of stress, a moderation effect which is partially mediated by stronger beliefs in God-mediated control (that God is a collaborative partner in dealing with problems). We conclude by proposing some interventions for clinicians and counselors centered around gratitude and religiosity that may assist older adults in coping with major life stressors."
Our read: This fascinating study examined whether gratitude toward God in aging adults could lessen the negative health effects of common stressful events, such as personal illness or a loved one's death. And of course, the researchers found that it did! This certainly makes a good case for Christian professionals and ministries to incorporate gratitude in their practices.
"How Gratitude Can Help Combat Climate Change"
Andrew Serazin and Robert A. Emmons, Time, November 12, 2021
"Insomuch as gratitude implies living in celebration, the healing of disconnection, and preserving and protecting what we most treasure, according to philosopher Nathan Wood, it has a unique advantage as a human virtue in that it can function both as 'an attitude of thankfulness in response to a benefit received' and in a non-instrumental sense as 'an active appreciation that something is the way it is.'
"Most importantly, gratitude is an action word. It is not passive. Grateful people are 'trustees,' caretakers of that which has been entrusted to them. Ingratitude, conversely, is a failure to preserve and protect the gifts that one has received or has been entrusted with. … People who experience environmental gratitude are morally concerned and intrinsically motivated to act responsibly."
Our read: Robert Emmons is the most well-respected scholar specializing in the study of gratitude, and he's also a committed Christian. This article offers a great deal of food for thought, whatever your ecological opinions. It's fascinating to consider the correlation between our gratitude to God and our posture toward the natural world he created and called us to cultivate. That connection reaffirms the biblical mandate of stewarding the earth, rather than treating it as a proprietary tool to serve our own interests.
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"The Concept of Gratitude in Philosophy and Psychology: An Update"
Liz Gulliford and Blaire Morgan, Journal for Ethics and Moral Philosophy, April 2021
"We have been able to examine claims about the nature of gratitude, such as whether it requires supererogation, whether benefactors' intentions rule out gratitude (they do not), and whether gratitude is a quintessentially positive and unalloyed good, as many have supposed."
"We align with those who argue that gratitude must be taught in a way which foregrounds its status as a virtue (Navarro & Tudge, 2020), which needs to be cultivated with an awareness of its relation to other moral principles and virtues with which it may even conflict (Jackson, 2016). This approach is necessary if we are to see beyond advocating gratitude instrumentally for its beneficial effects, which risks losing sight of moral reasons for cultivating this valued human strength."
Our read: In this follow-up to a 2013 study, the authors survey contemporary research on gratitude and also review recent changes and areas of growth in their burgeoning field of study. What I like most: They discuss the importance of cultivating gratitude as a virtue, whether or not it serves us. That claim confronts some corners of secular psychology, which promote virtues like gratitude as good, but only to the degree that they perform a positive function in our lives—as in, only if they make us feel "happy."
"The Virtue of Gratitude"
Peter Hill, Center for Pastor Theologians, November 2020
"How has the Christian faith and its virtue tradition influenced the science of positive psychology and virtue research? Many social scientists acknowledge that virtue reaches its full expression when embedded in a tradition, such as the Christian tradition."
"Gratitude, for instance, involves the realization that the good that comes to us in our lives often comes from a source outside of ourselves, which Christians often associate with God. We discuss these and other questions, including how pastors and Christians can cultivate the virtue of gratitude."
Our read: In this podcast episode, Peter Hill, professor of psychology at Biola and one of the foremost scholars on the subject of Christian virtue, explains how Christians have earned a sizable seat at the table in the field of positive psychology and how they've grounded the study of gratitude in God. For believers, locating gratitude inside a faith framework makes the practice of giving thanks far more resilient than it would if we leaned only on the fickleness of human nature.
"Gratitude to God: Psychological, Philosophical and Theological Investigations"
Biola University and the John Templeton Foundation, "Gratitude to God"
"To date we have completed five studies on gratitude to God (GTG). … In these studies, we also showed that GTG prospectively predicted spiritual well-being, general gratitude, and confidence in the existence of God. The model that emerged out of these studies was that GTG prospectively led to generalized gratitude, which in turn enhanced subjective well-being. We are sanguine that this research program will help jumpstart the empirical science of GTG and provide the foundation for future investigations into the nature, causes, and consequences of theistic gratitude."
Our read: It's exciting to see divine gratitude explored as a topic of serious academic inquiry—and even more exciting that Christian academics are leading the charge. In fact, "gratitude to God" is now the subject of a nearly $4 million John Templeton Foundation grant, awarded through Biola, that will fund a number of intriguing research proposals to be published next year. The venture is led by top Christian scholars of gratitude, including Peter Hill, Robert Emmons, Robert C. Roberts, and Miroslav Volf.
"The current scientific literature on gratitude toward God is severely limited," noted the research team, given that "across theistic traditions, God is viewed as the source of all good, and this realization highlights the priority of divine goodness over every other created good."
Discipleship | Gratitude | Science | Sociology | Thanksgiving
More From: Stefani McDade
Theology and Ethics
Evangelicals Have Made The Trinity a Means to an End. It's Time to Change That.
For 2,000 years, church leaders held to the same Trinitarian doctrine. How did we lose our way?
Matthew Barrett
Parents Set the Pace for Their Adult Children's Religious Life
"Handing Down the Faith" shows a vast majority of Americans don't choose their religious beliefs. They inherit them.
Christian Smith and Amy Adamczyk


text:
var dgram = require('dgram')

var DELAY = 800
var FREQ = 100
var lastSend = 0

module.exports = {
  init: init,
  send: send,
  getVersion: getVersion,
  getSerial: getSerial,
  getEnergy: getEnergy
}

var sequenceNumber = 100;
var callbacks = [];
var version = "Unknown"
var serial = "Unknown"
var energy = "Unknown"

var server = dgram.createSocket("udp4");

var queue = [];

function getVersion() {
  return version
}

function getSerial() {
  return serial
}

function getEnergy() {
  return energy
}

server.on("error", function (err) {
  console.warn("server error:\n" + err.stack);
  server.close();
});

server.on("message", function (msg, rinfo) {
  var str = String(msg)

  if (str.charAt(0) == '*') {
    var obj = JSON.parse(str.substring(2))

    if (obj.type == 'hub') {
      version = obj.fw
      serial = '74:0A:BC:' + obj.mac
    } else if (obj.type == 'energy') {
      energy = obj.cUse
    }
  } else {
    var recvSequenceNumber = 'S' + String(msg).substring(0, 3)

    var callback = false

    if (callbacks[recvSequenceNumber]) {
      callbacks[recvSequenceNumber](msg, rinfo)
      delete callbacks[recvSequenceNumber]
      callback = true
    }
  }

  console.log("recv: " + String(msg).replace('\n', '') + " (callback=" + callback + ")")
});

server.on("listening", function () {
  server.setBroadcast(true);
});

server.bind(9761);

function init(callback) {
  send("@H", "", "", "", "Retrieving", "Version", null)
}

function send(command, room, device, func, line1, line2, callback) {
  for (i = 0; i < queue.length; i++) {
    if (queue[i].room == room && queue[i].device == device && queue[i].func.substring(0,1) == func.substring(0,1)) {
      // removedCallback = queue[i].callback

      console.log('Duplicate message dropped ', JSON.stringify(queue[i]))

      queue.splice(i, 1);

      //removedCallback("100,OK", null)
    }
  }

  if (callback) {
    callback("100,OK", null)
  }

  queue.push({command: command, room: room, device: device, func: func, line1: line1, line2: line2, callback: callback});
}

function sendFromQueue() {
  var now = new Date().getTime()

  if (now > lastSend + DELAY) {
    var command = queue.shift();

    if (command) {
      var buffer = new Buffer(sequenceNumber + "," +
        (command.command? command.command : "!") +
        (command.room? "R" + command.room : "") +
        (command.device? "D" + command.device : "") +
        (command.func? "F" + command.func : "") +
        "|" + (command.line1? command.line1 : "") +
        "|" + (command.line2? command.line2 : "") +
        "\n");

      // if (command.callback) {
      //   callbacks[String('S' + sequenceNumber)] = command.callback;
      // }

      if( sequenceNumber++ == 1000) {
        sequenceNumber = 100;
      }

      console.log("send: " + buffer.toString().replace('\n', ''));

      server.send(buffer, 0, buffer.length, 9760, "255.255.255.255", function(err, bytes) {
        if (err) {
          console.error(err);
        }
      });
    }

    lastSend = now
  }
}

setInterval(sendFromQueue, FREQ);