text:
Q: meaning of segment outgoing in expedia air api result I am implementing expedia Air API in my php web site. I have sent air availability result and I got the result (in xml format). In the result there is a term segment
outgoing="true" and segment outgoing="false"
what is it mean? I read the API doc several times. But I couldn't solve my problem. I think segment outgoing="true" means it's the flight from my departure place (i.e. towards the destination) and segment outgoing false means flight starts from my arrival place. I will explain what I mean
If I want to send a round trip request (Cochin to Delhi). From this example
Segment outgoing true means -> flight from Cochin to Delhi
Segment outgoing false means -> flight from Delhi (return flight)

Is my concept is correct? If not please give me a reply
Also how I will find out the price from the xml result?
Thanks in advance

redpajama_set_name: RedPajamaStackExchange


Great food as well as music are the aspects that make a night spot an ideal place for leisure after a long active day. Some bars will certainly showcase real-time bands therefore the music could be loud sometimes yet in conclusion, these areas are still perfect for leisure if like this type of home entertainment. M15 Show Bar as well as GrillThis bar has actually been giving individuals of Corona remarkable amusement. The food as well as drink options are fantastic as well as the music is excellent also. You and also your friends will certainly locate this area ideal for an evening of amusement. The place will definitely rejuvenate your weary hearts after you tasted its food and paid attention to its songs. The main function of this bar are the singers as well as live bands carrying out on their large performance phase. Inside, it seems like you are in a complete sized concert while paying attention to popular bands sings their perpetuity appeals stage. It is modern for this reason it is capable of supplying crisp as well as loud music to everyone. Meanwhile neighborhood artists in Corona also give home entertainment to the group periodically. On the other hand, those who are waiting to drink can benefit from M15s regional as well as imported drinks. Ultimately, you could book a private event here. Food and drinks are the leading facets of an awesome bar. But it will certainly stand apart even more if it has online band playing your perpetuity preferred music as a type of amusement. No matter exactly how exhausted and also weary you are, the atmosphere inside will undoubtedly rejuvenate your soul. M15 Show Bar and also GrillOne of the outstanding nightclub in Corono is the M15 Show Bar as well as Grill. Inside you will certainly discover terrific ambiance as well as remarkable songs. The food choice right here is superb, it will absolutely please you yearnings yet it will certainly not your pocketbook. You as well as your friends will certainly have an incredible eating experience right here. On the various other hand, bench section serves both imported as well as regional beverages for your pleasure. Clients will be dealt with to loud music many thanks to the bars state of the art sound system.


Delivery of all types of stone and gravel. Leveling and rotarvation. Digger hire also available.
Mini-digger with operator available for your landscaping requirements. Call for a competitive, no obligation quotation.
1.6 ton Mini-digger for ground clearance, landscaping, ponds.
Fully registered and insured in France all work guaranteed.Referances available on works completed in France.
1.6 ton Mini-digger with fully experienced driver for hourly hire. Registered and insured.Competitive rates.
Mini-digger with operator. Call for a competitive, no obligation quotation. Vendee & Deux-Sevres.


The First Plan was for the present year which comprised the annual budget and the Second was a plan for a fixed number of years, which may be 3, 4 or 5 years. Plan number two kept changing as per the requirements of the Indian economy .... 11 th Five Year Plan (2007 -2012) In 11th 5 year plan, Rs 1, 28,500 Crores has been allocated as limit Rs. 1, 11,111 crores. Allocation of Rs. 53830 crores was granted, with the view of special priority given to social service sectors.
11 th Five Year Plan (2007 -2012) In 11th 5 year plan, Rs 1, 28,500 Crores has been allocated as limit Rs. 1, 11,111 crores. Allocation of Rs. 53830 crores was granted, with the view of special priority given to social service sectors. wondershare link excel to pdf file The First Plan was for the present year which comprised the annual budget and the Second was a plan for a fixed number of years, which may be 3, 4 or 5 years. Plan number two kept changing as per the requirements of the Indian economy .
11 th Five Year Plan (2007 -2012) In 11th 5 year plan, Rs 1, 28,500 Crores has been allocated as limit Rs. 1, 11,111 crores. Allocation of Rs. 53830 crores was granted, with the view of special priority given to social service sectors.
The 12th Five-Year Plan (2011-15) period has seen great improvements being made in the income distribution system. China enters key phase to avoid middle income trap China is set to avoid the middle income trap in the next five to 10 years as innovation and structural adjustment will boost medium-to-high speed growth.


African countries should scale up their efforts towards economic re-integration and combined efforts in stamping-out the scourge of terrorism within African Sates.
This was the advice given by the Ambassador of Nigeria to Korea, Ambassador Desmond Akawor, who is equally the Dean of African Ambassadors accredited to Republic of Korea.
This advice was given when the New Ambassador, H. E. Amb. Otman S. Saadahbara paid courtesy call on the Dean in his office on arrival in South Korea.


HAC -"Hi A/C" is designed to allow any power hungry component to effortlessly draw current from your supply. The HAC consists of nine individually Teflon® insulated shielded conductors. HAC cord can handle the demands of both low and high wattage equipment. This cord has been tested with 1000W monoblocks and worked with extremely low resistance and no stress. Source components also benefit from the quality, shielding, and effortless power draw provided by the HAC.
Three runs of Teflon® insulated silver plated oxygen-free copper wire for each: "phase", "return" and "ground" (i.e. nine runs altogether); Three separate silver plated "source-terminated" shields: an individual shield for "phase", "return" and "ground"; Double Teflon® insulation (rated at 1500V continuous) - internal, between the central conductors and the shield, and outer - show-white, plus black mesh outer jacket; Arrow Hart 6266 HG hospital-grade (green dot) AC plug, rated 15A/125V; American-made IEC plug with built-in strain relief, rated 15A/125V.
The HAC cord has been compared to AC cords from Cardas, Kimber, Sinergistic Research, Audioquest, Classe, Marigo, and others - in several different audiophile systems. None of the mentioned cords sounded as good as the HAC. The HAC - like all STEALTH AC cords - is conceptually different from the majority of audiophile cords of the market. AC power cords' "sound" mostly depends not on the AC carrying wires, but on the ground wire, which NEEDS to be shielded since it's included into the sound SIGNAL PATH (ground path, to be more precise) - that's largely why different AC power cords sound different from each other! AC is filtered in the power supplies, but the ground goes in and out just the way it is. Therefore, in general, the better your house ground wiring is, the more obvious are the HAC sonic advantages. But all the technical justifications and positive reviews do not matter as much as the improvement this cord will make on YOUR system.
Please check the latest reviews and customers' feedback on the HAC AC power cables.
"... I have the STEALTH HAC cables plugged in my speakers and DAC and they definitely improved the sound quality"
"...STEALTH HAC A/C cable made a very noticeable improvement in my system, more air around instruments and voices, better midrange and bass."
"... I recently installed an HAC cord in my VSP Labs Power Amp. Wow, what a difference!"
Suggested retail price for a 1.2 meter long HAC is $425.00 Please add $175 for each additional meter.


text:
Das Depot von Lunow ist ein archäologischer Depotfund aus der Frühbronzezeit, der bei Lunow (Landkreis Barnim) entdeckt wurde.

Der erste Hortfund wurde in einer "Steingrube" (möglicherweise Steinbruch?) entdeckt und besteht aus einem Ring mit abschmalenden Enden und einem langgestielten Meißel.
Der zweite Hort setzt sich aus einer Stabdolchklinge, einem Randleistenbeil, zwei Ösenhalsringen, zwei Armringen, einer Armspirale und einem Manschettenarmband zusammen und wurde möglicherweise in einem Gefäß niedergelegt. Beide Depots werden der Aunjetitzer Kultur zugeordnet.

Der erste Hortfund ist heute nicht mehr vorhanden, der Zweite befindet sich im Museum für Vor- und Frühgeschichte Berlin.

Literatur
 Waldtraut Bohm: Die ältere Bronzezeit der Mark Brandenburg. Berlin/Leipzig 1935.
 Rolf Breddin: Der Aunjetitzer Bronzehortfund von Bresinchen, Kr. Guben. In: Veröffentlichungen des Museums für Ur- und Frühgeschichte Potsdam 5. Potsdam 1969. S. 15ff.
 Bernd Zich: Studien zur regionalen und chronologischen Gliederung der nördlichen Aunjetitzer Kultur. 1996.

Lunow
Archäologischer Fund (Bronzezeit)
Lunow
Aunjetitzer Kultur
Museum für Vor- und Frühgeschichte (Berlin)
Bronze

redpajama_set_name: RedPajamaWikipedia


Definition - What does Referrer mean?
A referrer is URL data from an HTTP header field identifying the Web link used to direct users to a Web page. Referrers are used in statistical Web analysis and often integrated with marketing strategies and security methodologies.
A referrer is also known as an HTTP referrer.
A referrer is commonly used to combat cross-site request forgery (CSRF), which is unauthorized or malicious activity from a trusted website user. The ease of disabling or forging referrers weakens security mechanisms.
Some Web browsers, proxies and firewall software allow user referrer disabling. On the flipside, published referrer links allow bloggers to attract readers, enhance communication and expand blogging communities. However, this practice can lead to increased referrer spam.
Most Web servers log all traffic, including referrer information, increasing privacy concerns. Thus, some Web servers are barred from receiving referrer information. Referrer data is often blanked out by Internet security applications.
When the refresh command is used, most Web browsers do not send referrer data. The World Wide Web Consortium (W3C) discourages this practice.


Some finished renders of the Hyperion, Phil Bono's SSTO design.
This view has some perspective, and I have added a figure for scale.
The Hyperion coasting over Earth.
And another view at orbital altitude.
Here are some perspective free views, two with the legs down, and two with the legs up. Note that I also added a small human figure for scale in the bottom left!
As usual, all this was done in Lightwave 3d.
Is it just me or does that look like a large version of the Dragon v2 from SpaceX? The Dv2 seems to be designed to land and take-off from Mars, which with it's thinner atmosphere and lower surface gravity requires a lot less dV to reach orbit.
I see what you mean – though the scale is way differenT!


text:
Used Land Rover Discovery Cars For Sale
Honest John Used Search » Land Rover » Discovery »
Select Land Rover (329)
Select Range Rover Evoque (958) Discovery Sport (664) Range Rover Sport (459) Range Rover Velar (334) Discovery (329) Range Rover (236) Defender (118) Freelander (40) 400 (1)
Select Estate (66) Pick-up (11) SUV (229)
Select 2.0 (64) 2.5 (2) 2.7 (3) 3.0 (217) 3.9 (2)
Select SD4 (57) Si4 (7) TD (1) Td5 (1) Td6 (93) TDi (1) TDV6 (10)
Select First Edition (4) Graphite (6) GS (3) HSE (121) HSE Luxury (115) Landmark (20) LE (1) R (1) R-Dynamic HSE (2) R-Dynamic SE (3) S (5) SE (23) SE Tech (2) XS (8)
Select Diesel (316) Petrol (13)
Select Black (65) Grey (65) Silver (43) Blue (41) White (39) Red (11) Orange (8) Green (5) Gold (4)
Select automatic (70) Automatic (253) manual (6)
Select up to 100 miles (1) up to 5,000 miles (9) up to 10,000 miles (33) up to 20,000 miles (87) up to 30,000 miles (138) up to 40,000 miles (207) up to 50,000 miles (238) up to 60,000 miles (268) up to 70,000 miles (286) up to 80,000 miles (298) up to 90,000 miles (306) up to 100,000 miles (308)
Select from £500 from £3,000 from £5,000 from £6,000 from £8,000 from £9,000 from £10,000 from £11,000 from £12,000 from £13,000 from £14,000 from £16,000 from £19,000 from £22,500 from £25,000 from £27,500 from £30,000 from £35,000 from £40,000 from £50,000 from £75,000
Select to £3,000 to £5,000 to £6,000 to £8,000 to £9,000 to £10,000 to £11,000 to £12,000 to £13,000 to £14,000 to £16,000 to £19,000 to £22,500 to £25,000 to £27,500 to £30,000 to £35,000 to £40,000 to £50,000 to £75,000 to £100,000
Looking to save on insurance?
We all worry about the rising cost of car insurance, but with a little help, you'll discover there are plenty of simple ways to make huge savings on your car insurance.
Save On Car Insurance
Land Rover Discovery Estate
Land Rover Discovery Pick-up
Land Rover Discovery SUV
Browse by engine
Land Rover Discovery SD4
Land Rover Discovery Td6
Land Rover Discovery TDV6
Land Rover Discovery HSE
Land Rover Discovery HSE Luxury
Land Rover Discovery Landmark
Land Rover Discovery SE
3.0 SD6 HSE 5dr Auto
Marshall Land Rover Oxford
2.5 TDI 5DR AUTOMATIC
D A Car and Commercial
Greenpoint Car Sales Ltd
2005 LAND ROVER DISCOVERY 3 2.7 Td V6 S AUTO 7 SEATS JUST 158,000 MILES FSH
Eco Cars Cheshire
2.7 3 TDV6 SE 5DR AUTOMATIC
3.9 LAND ROVER DISCOVERY
Auto Select Bedford Ltd
2.5 Td5 GS 5 seat 5dr Auto
Compare new Land Rover Discovery deals
Buy new from £56,007 (list price from £57,940)
Land Rover Discovery (2017 on)
Land Rover Discovery 4 (2009 - 2017)

redpajama_set_name: RedPajamaCommonCrawl


text:
Алекса́ндр Ива́нович Ивано́в (1923—1945) — Герой Советского Союза, комсомольский организатор стрелкового батальона 811-го стрелкового полка (229-я стрелковая дивизия, 21-я армия, 1-й Украинский фронт), младший лейтенант.

Биография
Родился в 1923 году в деревне Паршино (ныне — Торопецкого района Тверской области) в семье крестьянина. Русский. В 1937 году окончил семилетку, стал заведовать библиотекой Куньинского сельсовета. Затем работал в колхозе «Россия» счетоводом.

С началом Великой Отечественной войны в армию не призвали по возрасту, остался на оккупированной территории. Жил в деревне Пестряково. Связался с партизанами, хорошо зная местность, молодой разведчик приносил ценные сведения о расположении фашистских войск.

В марте 1942 года был призван в Красную Армию. Окончив краткосрочные курсы артиллеристов, уже в июне того же года был на фронте. Командир орудия, сержант Иванов получил боевое крещение в районе города Холм и заслужил первую награду — медаль «За отвагу».

Через год окончил курсы младших лейтенантов и прибыл в 811-й стрелковый полк на должность командира взвода. В 1944 году был принят в ВКП(б). За несколько месяцев боев молодой командир взвода получил 19 благодарностей командования. Много раз возглавлял разведывательные рейды в тыл противника, добывая командованию ценные сведения, помогавшие наносить по врагу ощутимые удары. Лично участвовал в захвате 13 «языков».

Вскоре был назначен комсоргом стрелкового батальона. Он не засиживался в штабе, днями и неделями жил в ротах, рассказывал молодым о прошедших боях, о своих вылазках в тыл врага, показывал боевые приемы и навыки, проводил комсомольские собрания. В боях личным примером бесстрашия увлекал бойцов на штурм вражеских позиций.

3 февраля 1945 года в бою за населённый пункт Шургаст (ныне Skorogoszcz, 20 км северо-западнее города Ополе, Польша) погиб командир батальона, и комсорг Иванов принял командование на себя. Продвижение батальона приостановилось из-за сильного пулемётного огня, который велся из сохранившегося дзота. Все попытки подавить огневую точку успеха не имели. Младший лейтенант Иванов незаметно подкрался к немецкому дзоту, бросил несколько гранат. На какой-то миг наступила тишина. Потом вражеский пулемет снова заработал. Тогда комсорг своим телом закрыл амбразуру пулемётного дзота. Воины поднялись в атаку, и поставленная перед подразделением задача была полностью выполнена.

Похоронен в районе города  (Польша).

Награды
Указом Президиума Верховного Совета СССР от 10 апреля 1945 года за образцовое выполнение боевых заданий командования на фронте борьбы с немецко-фашистским захватчиками и проявленные при этом мужество и героизм младшему лейтенанту Иванову Александру Ивановичу посмертно присвоено звание Героя Советского Союза.

Награждён орденами Ленина, Отечественной войны 2-й степени, медалью «За отвагу».

Память
На здании правления колхоза «Россия» Торопецкого района установлена мемориальная доска.

Литература

Ссылки

Разведчики Великой Отечественной войны
Участники Великой Отечественной войны, закрывшие телом амбразуру


A core value of the Durham-Chapel Hill Jewish Federation is Tikkun Olam (repairing the world). The Nancy Gordon Social Justice Fund was established to provide scholarships to teens and young adults up to age 25, to travel locally or abroad (Israel) to participate in a social justice focused program.
If you are interested in helping to support this program, you can send donations or tribute gifts to: The Nancy Gordon Social Justice Fund at the Jewish Community Foundation.
Applications for 2020 will be due April 1, 2020. Please fill out the Social Justice Experience Scholarship Application and email completed application to Foundation@shalomdch.org.
In 2019, the Scholarship Committee awarded one scholarship to an individual, Hannalee Isaacs, so she could participate this summer in the Religious Action Center L'Taken program. This program allows participants to be exposed to a variety of public policy issues and explore Jewish values that inform advocacy around the issues.
In 2018, the Scholarship Committee awarded one scholarship to a group of UNC Hillel students who participated in a week-long Alternative Spring Break service trip with Repair the World in Brooklyn, New York. The students volunteered at two soup kitchens, two food pantries, two schools, an urban farm and a prison book project. They visited the Tenement Museum and explored the history of Jews in New York City and Brooklyn. They canvased for SNAP and explored Jewish food justice. They experienced two Brooklyn Jewish communities for Shabbat and visited Moishe House in Park Slope. The hands-on work and learning made quite an impact on the participants.


After years of recurring ankle problems, I finally decided to get my condition checked out at FPC. Dr. Reyneker patiently explained the biomechanics involved in walking and helped me comprehend the aches and pains I often felt. With this clearer understanding, I could better appreciate the treatment processes and rehab exercises prescribed, both of which have since been progressing well. Looking forward to prevent future ankle issues through this treatment journey. Many thanks to Dr. Reyneker and his team for helping me address my problems.


When I dyed my hair I was a bit lost when it came to colours. I wasn't sure what colours would look good on me, what colours I should stop wearing, etc. Over time I realised the best way to figure that out was to wear everything and see for myself.
When I saw this top online I got scared. I decided to order it anyway. I loved the fit and the cutouts on the sleeves and decided to give it a chance. And I couldn't be happier!
The top looks amazing even though it's a colour so similar to my hair colour, I love the cutouts and the bell sleeves and I think it's the perfect pop of colour when pairing it with such neutral tones as I did here.
Did you have the same insecurities that I did? Are there any colours you're afraid of wearing? Tell me in the comments below!
I got this powder a while ago and decided it was time for me to review it as I have a few things to say about it. Some are positive, some are negative but you know that I don't like to talk much about the bad things about something but when it comes to reviews, I like to be honest and I have to mention the bads so that people thinking of buying the product can be aware of it and also so that brands can improve their products. Never forget that there's a big difference between hate and constructive criticism, many people don't know the difference... Say what you mean but don't say it mean.
But moving on to the actual review. I thought the concept of this product was really interesting. A normal powder when used dry, foundation when used wet. The description says that dry, it has a low to medium coverage while wet has a medium to high coverage. After trying it out both ways I can say that description is a bit of a stretch.
First Impressions. The packaging is really nice, I like it, it's sleek and easy to carry with me and because it comes with a sponge, it's easy to touch up throughout the day. The powder is super fine and lightweight and doesn't have any fallout. It's really soft and moisturizing.
At first, I tried it as a powder, with a big kabuki brush. It mattifies my skin but doesn't make me look flat, it's not drying or cakey and doesn't cling to my dry patches. When it comes to my pores, I was kind of expecting it to blur them a bit but I feel like it accentuates them. With the face products I'm currently using, my pores end up disappearing but once I apply powder, it brings them back. It could be worse but it's still a downside.
For a couple of days, I used it as a foundation. I used the sponge it comes with to try and see how it applied and I wet it every time before using. The sponge soaks up a bit of product, it got really dirty and I could see the more I blended, the less coverage it had. That fact probably makes it look so natural and not cakey at all but I also don't really know how to use it or what to use it with to make it have more coverage. Any tips, please leave them in the comments. I'd definitely use it more as a foundation because I really like the finish and the coverage but there's a huge reason for me not to. It has an awful red undertone. While applying it, I could see that it was making my face a different colour but was only when I finished and looked at myself in the mirror that I noticed how red my face was. I would've loved to use it wet because it does look beautiful but the red undertone ruins it completely.
Also, do you like the fake flowers I added to the pictures? Does it look nice or is it a bit too much? I think it looks nice but I think the flowers might look too fake, I need to work a bit more on it.


text:
Division last edited 29th Jan 2021 by mackay staff
8th Dec 2020, 4:45 PM – Representatives Corporations Amendment (Corporate Insolvency Reforms) Bill 2020 - Consideration in Detail - Review and sunset
The majority voted in favour of disagreeing with amendments introduced by Whitlam MP Stephen Jones (Labor), which means the amendments failed.
Jones explained that these amendments did two things:
Firstly, they impose a requirement for a statutory review, which I understand to be something that the government will support. Secondly, they impose a requirement that the new provisions be sunsetted. I understand that the government does not support that proposition. I just want to make clear that the sunset provision gives ample time for us to get through the crisis, for us to get through the stock of anticipated insolvencies, for a review to occur and for the emergency provisions to be sunsetted, unless they are altered by new provisions that may enjoy the agreement of both houses of this place.
(1) Clause 2, page 2 (at the end of the table), add:
6. Schedule 5 The day after this Act receives the Royal Assent.
(2) Page 104 (after line 16), at the end of the Bill, add:
Schedule 5—Review of provisions and sunsetting
1 Review of Act
(1) The Minister must cause a review to be undertaken of the operation of the amendments made by this Act.
(2) Without limiting subitem (1), the review must consider the following:
(a) the efficacy of the amendments;
(b) the appropriateness of the amendments as a permanent features of the insolvency regime;
(c) any further amendments recommended to be made to the insolvency regime if the amendments made by this Act operated for a longer period of time or permanently;
(d) the effect of the amendments made by this Act on unincorporated small business creditors such as sole traders and partnerships, including any increase in individual bankruptcies that are correlated with, or attributable to, the amendments.
(3) The review must commence no later than 31 December 2021.
(4) The person or persons undertaking the review must give the Minister a written report of the review by 31 March 2022.
(5) The Minister must cause a copy of the report of the review to be laid before each House of the Parliament within 15 sitting days of that House after it is given to the Minister.
2 Sunsetting of amendments
An Act that is specified in a Schedule to this Act is taken, on and after the following day, to have effect as if the amendments made by this Act to that Act had not been made:
(a) if paragraph (b) does not apply—31 December 2022; or
(b) if the review has not commenced by 31 December 2021 in accordance with subitem 1(3)—31 December 2021.
Corporations Amendment (Corporate Insolvency Reforms) Bill 2020
Garth Hamilton Groom


text:
KANDAHAR JOURNAL; SHH, IT'S AN OPEN SECRET: WARLORDS AND PEDOPHILIA
The following interview was reported in The New York Times on 21 February 2002. As explained on the page Greek love in India & Central Asia, it is presented here as a unique exception to this website's unwillingness to describe the practice of Greek love in the 21st century.
By Craig S. Smith 21 February 2002
Back in the 19th century, ethnic Pashtuns fighting in Britain's colonial army sang odes talking of their longing for young boys.
Homosexuality, cloaked in the tradition of strong masculine bonds that are a hallmark of Islamic culture and are even more pronounced in southern Afghanistan's strict, sexually segregated society, has long been a clandestine feature of life here. But pedophilia has been its curse.
Though the puritanical Taliban tried hard to erase pedophilia from male-dominated Pashtun culture, now that the Ministry for the Promotion of Virtue and Prevention of Vice is gone, some people here are indulging in it once again.
''During the Taliban, being with a friend was difficult, but now it is easy again,'' said Ahmed Fareed, a 19-year-old man with a white shawl covering his face except for a dark shock of hair and piercing kohl-lined eyes. Mr. Fareed should know. A shopkeeper took him as a lover when he was just 12, he said.
A Kabul street-boy, 2003
An interest in relationships with young boys among warlords and their militia commanders played a part in the Taliban's rise in Afghanistan. In 1994, the Taliban, then a small army of idealistic students of the Koran, were called to rescue a boy over whom two commanders had fought. They freed the boy and the people responded with gratitude and support.
''At that time boys couldn't come to the market because the commanders would come and take away any that they liked,'' said Amin Ullah, a money changer, gesturing to his two teenage sons hunched over wads of afghani bank notes at Kandahar's currency bazaar.
Most men here spend the vast majority of their time in the company of other men and rarely glimpse more than the feet of any woman other than their mother, sister or wife. The atmosphere leaves little room for romantic love, let alone recreational sex between men and women. But alternative opportunities are not hard to find.
Muhammad Daud, 29, says he first spotted Mr. Fareed seven years ago at an auto repair shop owned by Mr. Fareed's father and pursued the boy for months.
''If you want a haliq'' -- a boy for sex -- ''you have to follow the boy for a long time before he will agree,'' said Mr. Daud, smiling at Mr. Fareed in a hostel in Kandahar where the two consented to give an interview.
''At first he was afraid, so I bought him some chocolate and gave him a lot of money,'' said Mr. Daud, laughing. ''I went step by step and after about six or seven months, he agreed.''
''At that time, I had no beard,'' Mr. Fareed said, smiling.
The Taliban took care of that problem by resorting to an ancient punishment prescribed by the Shariah, a compendium of Islamic laws: they pushed a wall on top of anyone found to be homosexual.
Odd as the punishment sounds, it resonates with many Afghans who live in a world of mud-and-wattle walls, many of which have long since lost their usefulness. There are plenty of 12-foot-high, 2-foot-thick earthen walls around waiting to be toppled.
An Afghan dancing-boy, 2005
On the outskirts of Kandahar, Mr. Fareed pointed to a mound of rubble and described how he had watched the Taliban lay a man there in a shallow pit in front of a high wall and then ram the wall with a tank from the other side, knocking it over on top of him.
''When the wall fell, people said he was dead, but later we heard that he wasn't dead,'' said Mr. Fareed.
The man was Mullah Peer Muhammad, a former student of the Koran who had become a Taliban fighter and was later put in charge of boys then incarcerated at Kandahar's central prison. He was convicted of sexually abusing the inmates.
After the wall fell on him, his family dug him out and took him to the hospital. He spent six days there and another six months in jail, but according to the punishment, survivors are allowed to go free. He now lives in Pakistan, his former neighbors say.
A man who said he owns the wall that fell on Mr. Muhammad said he had seen the Taliban knock successive sections of the wall on another man seven times, digging him out each time and moving him along the remaining wall before he died. The man had been convicted of raping and killing a boy.
''We had to be very careful then,'' said Mr. Fareed, shrinking instinctively from the crowd that had gathered around the site during a reporter's visit. He said he and his lover could meet only at night in each others' homes, but that they tried to refrain from physical contact for fear that the Taliban's extensive intelligence network would discover them.
Now the Taliban are gone and the commanders have returned, some with their predilections. The problem is so widespread that the government has issued a directive barring ''beardless boys'' -- a euphemism for under-age sex partners -- from police stations, military bases and commanders' compounds.
While men are courting boys once again, few do so openly.
''Still, we feel ashamed in front of our older brothers or parents,'' said Mr. Fareed.
But he insisted that he does not regret being lured into a relationship by his older friend. When asked if he would do the same to a young boy, Mr. Fareed said, yes.
''I'm looking for one now,'' he said with a smile.
If you would like to leave a comment on this webpage, please e-mail it to greek.love.tta@gmail.com, mentioning in the subject line either the title or the url of the page so that the editor can add it.
Anon. 4, 28 February 2018
The acquaintance of one of my friends served in the U.S. forces stationed in Afghanistan a few years ago. The soldier's letters home told of officers admonishing their men to be wary of Afghani boys who'd approach them for relationships, of the accepted tradition of boys vying with each other for relationships with masculine authority figures—from tribal chieftains to Americans in uniform. He reported the astonishment on the faces of his buddies who, merely walking around a city's center or marketplace, would feel a small hand not reaching into his pocket but taking his hand with a beaming smile and wanting to be seen holding hands with a soldier. One of his platoon's gay confidants was outed as the result of a single tryst—because the boy bragged to his friends about "his" soldier's prowess, with the result that when he went out those boys mobbed him, seeking his favors.


text:
Drug Discov Ther. 2017 Nov 22;11(5):259-266. doi: 10.5582/ddt.2017.01052. Epub 2017 Oct 29.
Two-spotted cricket as an animal infection model of human pathogenic fungi.
Kochi Y1, Matsumoto Y2, Sekimizu K2, Kaito C1.
Laboratory of Microbiology, Graduate School of Pharmaceutical Sciences, The University of Tokyo.
Institute of Medical Mycology, Teikyo University.
Invertebrate infection models that can be evaluated at human body temperature are limited. In this study, we utilized the two-spotted cricket, a heat-tolerant insect, as an animal infection model of human pathogenic fungi. Injection of human pathogenic fungi, including Candida albicans, Candida glabrata, and Cryptococcus neoformans killed crickets within 48 h at both 27˚C and 37˚C. The median lethal dose values (LD50 values) of C. albicans and C. glabrata against crickets were decreased at 37˚C compared to that at 27˚C, whereas the LD50 value of C. neoformans was not different between 27˚C and 37˚C. Heat-killed cells of the three different fungi also killed crickets, but the LD50 value of the heat-killed cells was higher than 5-fold that of live fungal cells in the respective species. C. neoformans gene-knockout strains of cna1, gpa1, and pka1, which are required for virulence in mammals, had greater LD50 values than the parent strain in crickets. These findings suggest that the two-spotted cricket is a valuable infection model of human pathogenic fungi that can be used to evaluate fungal virulence at variable temperatures, including 37˚C, and that the killing abilities of C. albicans and C. glabrata against animals are increased at 37˚C.
Cricket; animal infection model; human pathogenic fungi; temperature; virulence
10.5582/ddt.2017.01052
Body Temperature*
Candida glabrata
Candidiasis*
Cryptococcosis*
Disease Models, Animal*
Fungal Proteins/genetics
Gene Knockout Techniques
Gryllidae*
Fungal Proteins
J-STAGE, Japan Science and Technology Information Aggregator, Electronic
Yeast Infections - MedlinePlus Health Information


This has come to my notice that most students who have the intention of schooling abroad in Canada finds it so difficult to choose a school of their choice according to courses and academic performance. This post will guild you on how to choose the Top 10 universities in Canada.
Lets the count begins From 10th to 1st.
Queen's University: Queen's is Canada's definitive university experience. At Queen's, we challenge and support in equal measure. When studying at Queen's, you can expect to be exposed to innovative concepts, different ideas, and new ways of thinking. We will provide you with the tools and resources needed to help you succeed. One of Canada's oldest degree-granting universities, established by Royal Charter in 1841, Queen's is home of 2015 Nobel Prize winner, Dr Arthur B. McDonald.
The University of Calgary: This is Canada's leading next-generation university; a living, growing and youthful institution that embraces change and opportunity with a can-do attitude in Canada's most enterprising city. The university has a clear strategic direction to become one of Canada's top five research universities by 2016, grounded in innovative learning and teaching, and fully integrated with the community of Calgary. Supporting industry and businesses locally, nationally and internationally, the University of Calgary strives to serve the community and reflect its values, while working to find solutions to some of the most challenging problems facing society today. As a major Canadian research-intensive institution, the University of Calgary has 14 faculties, 53 departments and more than 200 academic programs.
University of Western Ontario: This university is ranked as one of Canada's top research universities. From fundamental to applied knowledge, Western discoveries benefit economic, social, health and cultural development in Canada and around the world.
The University of Waterloo: This university has been ranked Canada's most innovative university for the past 25 years. More than 16,000 undergraduates participate in the world's largest post-secondary co-operative education program where students alternate school and work terms, gaining experience with employers such as Google, Facebook, Amazon. Located about 110 km west of Toronto, the University of Waterloo welcomes 35,000 students from 120 countries.
McMaster University: This university has a 129-year tradition of fueling curiosity, inquiry and discovery. Every day, we push the boundaries of knowledge through our ground-breaking approaches to teaching and learning and our world-class, interdisciplinary research. With students and faculty from 98 countries worldwide and 70 international academic exchange agreements in place, we celebrate diversity and welcome international perspectives. We are the only Canadian host site of a United Nations University (The Institute for Water, Environment and Health- UNU-INWEH) and are committed to creating a brighter world by advancing human and societal health and well-being.
The University of Alberta: This is one of Canada's top universities and among the world's leading public research-intensive universities, with a reputation for excellence across the humanities, sciences, creative arts, business, engineering, and health sciences. Home to world-leading facilities such as Canada's National Institute for Nanotechnology. Our students choose from 400 undergraduate, graduate, and professional programs in 18 faculties. We lead the country with the most 3M national teaching fellowships (Canada's highest award for undergraduate teaching excellence). With over 100 years of history and 250,000 alumni, the U of A is known globally for equipping graduates with the knowledge and skills to be tomorrow's leaders.
This post will give you an insight of top 10 universities in canada and courses offered.
Previous Post:Uppsala Scholarships for International Students to Study in Sweden.
Next Post:List of Universities in USA without application fee for international Students.


text:
INFOGRAPHIC: How Millennials Use Technology & Social Media for Good
We're all familiar with the negative stereotypes associated with young adults and technology. But did you know they're actually using their devices to make a difference?
Report: Teens Are Dominating Tumblr, Millennials Love Twitter
Millennials Are Snubbing the Corporate World for Entrepreneurship (Infographic)
Why it Pays to Reach Young Millennials With Your Marketing Strategy
5 Tips for Marketing to Millennials from a Millennial
Posted by Derek E. Baird on 02 October 2013 | Permalink | 0 Comments
Introducing finderyU
Findery, and the world, is your classroom!
While it may seem like you just wrapped up finals, packed up the classroom and headed for a well-deserved summer break, the (sad) truth is a new semester is right around the corner!
As you sit on that beach, you may be wondering how can you incorporate more project-based learning activities into your course syllabus and grab the attention of your students who, let's be honest, have the attention span of a gnat.
Even if you're not currently enrolled in college, Findery is a powerful informal learning platform where you can tap into the collective knowledge hidden in Findery Notes and learn (or share!) more about Australia, space travel, candy, San Francisco architecture or anything else that matters to you!
Introducing Findery University
Today I am happy to share the launch of Findery University!
Findery, is a geo-location based website where anyone can share local knowledge, hidden secrets, stories and information about the world around you. Using Findery, your students (or you!) can annotate places in the real world, leave media rich (YouTube videos, SoundCloud audio, Instagram and your own images) notes tagged to a specific geographic location.
You can even embed Findery notes into your class blog or website or share them via Twitter or on your classroom Facebook or Google+ page.
Findery for Students
Findery is a great way to create a multimedia project for just about any class. Demonstrate your learning by adding notes infused with video, images and text along the paths of your explorations. Ask your classmates to contribute their reflections, narrative feedback and resources on your Findery project through the comments.
Be sure to follow @Campus on Findery to discover and contribute notes about student life and campus history. Your notes could capture memories with your friends or pay it forward by joining the Findery Campus Challenge and leaving tips for your current and future classmates!
Findery University for Educators
Here are a few examples of how you can use Findery University to support formal and informal learning:
Are you a professor of film studies? Why not leave notes on the Findery map about the making of Giant? Or other famous movie locations?
Studying community supported agriculture? Investigate and map local food in your area, then leave notes for food sources with commentary on sustainability.
Have writer's block? Explore the notes in a particular region and build a story around the local knowledge of that place.
If you teach American Literature, create a Set that has Notes with facts, images or videos for books or authors included on your course reading list.
Encourage observation through illustrating places. Go on a sketching excursion and post a note with the picture of your sketch. Tag your notes with #sketchproject to contribute to urban sketching fans on Findery.
Use Findery as a way to create a living history map. Share a picture of your ancestors at the docks in Liverpool with an excerpt from their diary talking about how they feel about leaving England for America.
Share a note with a video clip about the hazards of transatlantic boat travel in the 1800s and include a passage from their diary about the challenges they faced during the journey. Bring your family history to life!
Enroll in finderyU
Go to findery.com
Click "Sign Up!" and follow the prompts. Don't be afraid of the FAQs
Update your settings, jump in and create your first note, or just start exploring
Download the free Findery University handout, or check out more lesson plan ideas at www.findery.com/university
It will be exciting to see how educators use Findery in the classroom, student projects or for your amazing passion projects!
Findery wants to share your Notes and lesson plans with our educator community. Send a tweet @finderyU or share the link on the Findery Facebook page, so they can share your FinderyU contributions!
And, oh--you can find me on Findery, here.
Posted by Derek E. Baird on 31 July 2013 | Permalink | 0 Comments
Study: 63% of College Students Actively Using Facebook or Twitter While Watching TV
Mobile is having the biggest impact on how college students apportion their screen time. Daily time spent on the computer and watching TV decreased in 2013, while daily time spent with the mobile phone and tablet were up by about 18 minutes each, compared with 2012.
But even if daily time spent watching TV is diminishing, a considerable 60% of college students reported owning a flat-screen TV; and TV viewing was still a major portion of students' media time, clocking in at 2.8 hours per day. While time spent on the computer or mobile may be higher, activity on these devices can run the gamut—from using a word processing program for schoolwork to making a phone call.
By comparison, when students turn on the TV, it is to watch a program, even if using other devices is a corollary part of the experience.
The study found that eight out of 10 college students reported using a second screen at least a few times a week while watching TV. Only 13% did so less than once a week, or not at all.
The most popular activity students engaged in while watching TV was using Facebook or Twitter, at 63% of respondents. Social TV can be boon to TV marketers and advertisers, but there is always the possibility that social networks are merely distractions from TV content.
Surfing the web was the next most common activity while watching TV, at 58% of respondents, while half also reported playing games. Schoolwork wasn't completely forgotten while students vegged out in front of the television, though—37% said they did homework or research while watching TV.
And in a sign that the second screen may be an opportunity for TV marketers and advertisers to gain student viewers' extra attention, about one-quarter of students looked up the TV schedule on a second screen, and about the same percentage shopped. (Source)
MTV Study: 57% of Millennials Like to Take a Break from Technology to Make Things with Their Hands
Humor: Binge TV Watching Now Leading Cause of Death Among Students
Startup promises more TV on campus
Forget second-screen apps. Today, the TV is the second screen
In a recent survey, MTV Insights set out to understand the younger end of the Millennial demo, 13-17 year olds, who will soon move into the "sweet spot" of MTV's core target demographic of 18-24 year olds.
This is a landmark generational study that builds on MTV's long legacy of deeply understanding their audience, as part of an effort to constantly reinvent ourselves and stay at the bleeding edge of youth culture.
One of the most interesting findings?
Of those who repsonded, 57% reported that they like to take a break from technology to make things with their hands…and 82% agree "when I'm stressed or overwhelmed, I like to stop and just do one thing at a time." As Julia, 17 puts it "When I craft I'm in the zone, it really soothes me."
With social media, crafts & baked goods are granted a "second life" and serve an important function in helping hone one's personal self-brand. We see teens today even more adept at developing their unique persona from a young age, realizing both the need to stand out to get social media likes and, moreover, showcase a unique side to get noticed in a highly competitive college admission process.
Why are younger Millennials so stressed?
They came of age in an economic downturn, seeing college grads struggling with huge student loan debt and living through a cascade of social media-amplified tragedies like Hurricane Sandy and Sandy Hook. For them, life has always been a 24/7 social media show.
Younger Millennials' "adaptive survival strategies"
Life-Prepping
These pragmatic youth are natural preppers in the face of an unpredictable world – whether planning for physically safety in light of violence or prepping for their futures in a more uncertain economic climate.
Accustomed to high school intruder drills, they are always in "exit strategy" mode, withover a third agreeing they "plot out escape plans when in public places, because of events like Sandy Hook." Although half are scared of violence at school, they seem to have adopted a practical "Keep Calm and Carry On" mentality.
Mono-tasking
YMs are consciously taking time to self-soothe (a classic coping mechanism from hyper-stimulation) disconnect, de-stress, de-stimulate and control inputs. They "mono-task" and focus on immersive hands-on activities like baking, sewing or crafting. They claim their dependence on social media is overrated: one girl says "My parents Facebook more than I do."
8 in 10 young Millennials agree that "Sometimes I just need to unplug and enjoy the simple things"
82% agree "when I'm stressed or overwhelmed, I like to stop and just do one thing at a time"
57% like to take a break from technology to make things with their hands
54% of 14-17 year old girls say baking makes them feel less anxious
Hyper-Filtering
This is the first generation of "digital latchkey kids." Though increasingly physically protected by parents, teens' web behavior is not as closely monitored. But like the Gen X Latchkey Kids who created their own rules and regimes while parents worked, youth today are surprisingly filtering out what's overwhelming to them online: avoiding certain Youtube videos or sites that they think are gross, inappropriate or disturbing.
They're slimming down their social networks and finding niche/private places to share in a controlled environment, whether it's Snapchat or a locked Instagram feed.
Unlike older Millennials who were pioneers in the "Wild West of social media," today's teens are "tech homesteaders" – they're more savvy about how to use the internet, build "gated" groups, "hide in plain view", curate and filter.
Source: MTV Insights | The New Millennials Will Keep Calm and Carry On
Infographic: Golden Rules for Social Media Use by Teens
The British Council is marking Social Media Day 2013 with a set of five golden rules to help parents and educators keep kids safe on social media.
Every year the British Council engages directly with up to two million children globally, and seven million indirectly through teaching, exams, programmes, and projects. The organisation is committed to keeping children safe and protecting them from all forms of harm and abuse.
Facebook for Education: Instagram in the Classroom
Here's a new Facebook for Educators handout that covers the basics of using Instagram, part of Facebook, in the classroom.
Feel free to share this, and our other (free!) Facebook Education handouts, with your colleagues, parents, youth pastor, coach or anyone who works with youth.
Related: Learn more about privacy on Instagram or get help with FAQs.
Instagram in the Classroom by Facebook for Educators
Click HERE to download the handout! It's free!
Preparing for Instagram as an advertising platform
Trend Watch: What do your Instagram posts say about you? It's high school all over again.
Mysterious Instagram hack returns, posting pictures of fruit and smoothies to users' accounts
COPPA 2.0: FTC Rolls Out New Rules for Mobile, Social and Geolocation Apps for Kids
Today the Federal Trade Commission (FTC) rolled out the biggest changes to the Childrens Online Privacy Protection Act (COPPA) since its launch in 1998.
For those of you not familiar with the law, COPPA regulates what information and data can be collected on children under 13.
The regulations relate to all aspects of privacy protection and are intended to give parents complete control over their children's personal information.
The refreshed COPPA rules take effect on July 1, 2013 and focus largely on the explosion of mobile devices, geolocation, mobile photography, social networking and app use by children under the age of 13.
FTC Resources
New suite of resources can streamline COPPA compliance
Complying with COPPA: FAQs
Children's Privacy Resources
COPPA: A Six Step Plan to Compliance
New Suite of Resources Can Streamline COPPA
Additional Resources & Information
COPPA: Helping Parents Protect Their Children (Fun Education Apps)
New Online Child Safety Rules Aim to Protect Kids on Smartphones, Social Media (NBC News)
COPPA: 10 Rules Every Business Should Know (VentureBeat)
Children's Online Privacy Rules Updated for Social and Mobile Era (Mashable)
Google Education Apps & COPPA (Google Apps Education Edition)
Privacy Alert: New COPPA Rules Effective July 1st (JD Supra News)
With Tighter COPPA Regulations, Librarians See Hurdles to Kids' Internet Use
Revised Children's Online Privacy Protection Rule Goes Into Effect Today
Marketing to Kids? Mind the New Children's Online Privacy Protection Act (COPPA) Provisions
COPPA: Revised Children's Online Privacy Protection Rule Goes Into Effect Today
How you see the world is at the heart of Instagram, turning it into the digital version of high school, complete with its own cliques and cast of characters.
If you think about it, it's not a surprise. After all, the idea at the heart of the social network is to use photos as a unique expression of your personality.
So when you choose what to capture and how to filter to get the right effect, you're not just composing a shot, you're revealing who you are. And like high school, those masterpieces peg you into broad archetypes, creating a Breakfast Club 2.0, if you will, for the 21st century.
Instead of jocks and cheerleaders roaming the halls or the cool clique smoking in the bathroom, you have visionaries, fashionistas, artistes and proud parents, each with their unique slant on the world, as well as hidden neuroses that make them human.
No matter what effect you lean towards or how much you crop, ultimately, you filter your sense of identity through the same lens that started to develop in high school — and it's what you carry through life, whether you realize it or not.
So where do you fit in? What do your Instagram posts say about you?
Photo Credit: eminic23
Posted by Derek E. Baird on 29 June 2013 | Permalink | 0 Comments
Facebook for Edu: Introducing Hashtags on Facebook
This week Facebook rolled out a new feature--hashtags!
Similar to other services like Instagram, Twitter, Tumblr, or Pinterest, hashtags on Facebook allow you to add context to a post or indicate that it is part of a larger discussion.
Here's a new handout that covers the basics of getting started using hashtags on Facebook, along with a quick look at hashtag privacy. Feel free to share this, and our other (free!) Facebook Education handouts, with your colleagues, parents or youth pastor.
Introducing Hashtags on Facebook by Facebook for Educators
Get the Official Facebook for Educators Guide
The Facebook for Educators Guide is available in English, Spanish, Portuguese and German. The guide is a collaboration between myself, Dr. BJ Fogg, Linda Fogg-Phillips and Facebook.
We invite you to join the conversation and share your best practices for using social media in the classroom with educators from around the world on our Facebook for Educators Page (http://www.facebook.com/FBforEducators).
You can find more free handouts, resources and profession development materials on our Scribd page (http://www.scribd.com/collections/2978485/Facebook-101).
Infographic: Teens, Social Media, and Privacy
Posted by Derek E. Baird on 21 May 2013 | Permalink | 0 Comments
Trend Watch: Is Teen TXTNG Killing Language? [VIDEO]
Does texting mean the death of good writing skills? John McWhorter posits that there's much more to texting -- linguistically, culturally -- than it seems, and it's all good news.
In this TED talk, linguist John McWhorter thinks about language in relation to race, politics and our shared cultural history.
Posted by Derek E. Baird on 22 April 2013 | Permalink | 0 Comments
Cyberbullying: A Sociological Approach [RESEARCH]
Social media and text messaging have assumed a dominant role in communication among adolescent society. And, as common in teenage social environments, these circumstances often involve online teasing and harassing. This has become known as "bullying."
Delaware state Attorney General, Beau Biden, describes cyber bullying as a communication that "interferes with a student's physical well-being, is threatening or intimidating, or is so severe, persistent, or pervasive that it is likely to limit a student's ability to participate in or benefit from the educational programs of the school."
According to Delaware Online, the state recently implemented a law enforcing that schools penalize cyber bullying issues the same as they would for incidents that happen within school walls.
Many states have begun to implement similar laws enforcing stricter punishments for those engaged in cyber bullying, and sometimes the victims are not only teens. NPR recently addressed a North Carolina law that was passed to protect teachers against bullying from their students.
A teacher at the Charlotte-Mecklenburg School had a student create a fake Twitter account under the teacher's identity, and posted offensive comments. Under new laws, students charged with such offenses could potentially face a month in jail and fines of up to $1,000.00.
The recent International Journal of Technoethics article "Cyberbullying: A Sociological Approach" evaluates the concepts of bullying and cyber bullying and addresses the emerging nature of these occurrences: "Cyberbullying has become a major social concern because it raises questions about the ethical use of technology.
In recent years, this has been the subject of research and information and prevention activities for different groups such as governmental and non-governmental organizations and schools and parents' associations to protect against the misuse of technology."
Written by José Neves and Luzia de Oliveira Pinheiro of the University of Minho, Portugal, the article features studies evaluating Portuguese University students in observation and focus groups, interviews, and investigations that aims to explore and define the characteristics of cyberbullying in Portugal.
Cyberbullying a Sociological Approach
Why Anti-Bullying Programs are Failing [VIDEO]
5 Signs your child is a cyberbully
Mobile Youth: Graham Brown on the Voices of a Mobile Generation
Cyberbullying Online - Statistics and What You Can Do About It
Search, Music and Social Networking Among Top Activities of UK Youth
UK teens have a significant presence online and are at the leading edge of many digital behaviors, according to a survey conducted by Research Now and initiated by K&A BrandResearch.
When UK teens go online—whether via PC or mobile—using search engines to seek out information is their No. 1 activity, in line with the ubiquity of this action among older age groups as well.
The next two most popular activities showed the ways in which teens' digital priorities may somewhat diverge from older consumers.
Just about 80% of UK teens said they went online to visit social networks. And another seven out of 10 used the internet to listen to music. These responses beat out email, watching video and playing games as teens' primary digital activities.
Read the rest of the article over on eMarketer
How the internet is kickstarting a teen poetry revolution
UK Teens Go Online to Look up Products and Compare Brand Prices
Facebook search limited for teens
INFOGRAPHIC: 81% of Americans use a smartphone and watch TV simultaneously
Trend Watch: Teen Girls, Social Media and the 'Thigh Gap' Obsession [VIDEO]
Quick. Here's a test: Stand-up straight with your feet together in front of a mirror and look for a space between your upper thighs. If you see a gap, you have the latest body image obsession teen girls are starving themselves to achieve.
The 'thigh gap', as it is known, is a new teen girl obsession with a huge following on social media sites like Tumblr, YouTube and Instagram.
The trend is fueled by digital media and magazines that feature celebrities with the elusive 'thigh gap'---which is, in most cases, the work of a highly skilled Photoshop guru and not so much based on reality.
Exposure to this dangerous body image trend is just an app click away---girls can read tweets from Supermodel Cara Delevingne about her thigh gap on Twitter or scroll through thousands of thigh gaps on Tumblr with images of ultrathin women in bikinis, super short skirts, and lingerie, all baring thighs so thin they don't touch.
Whether or not this is a widespread trend or just a blip across teen culture is yet to be seen. However, this is another example of where parents, teachers and youth pastors need to step-in and faciliate a discussion about body image, social media and celebrity culture with their kids.
And remember, body image issues aren't just a 'teen girl' issue.
While there has been lots of media coverage and press about young girls/women regarding body image & eating disorders, there has been very little devoted to how the media effects boys. In many cases, boys are an understudied group with regard to body issues (dysmorphia, bigorexia).
Even as the media continues its obsession (yes, Twilight I'm looking at you) for the almighty 'six pack', boys have been gaining on girls in eating disorders like anorexia and bulimia.
Boys and Body Image: Eating Disorders Don't Discriminate
Packaging Boyhood
Instagram Beauty Contests Worry Parents
Photo Credit: @ready_for_thynspo on Instagram
Related Thigh Gap Articles
Is 'Thigh Gap' The New Heroin Chic?
Is Your Daughter Worried about Thigh Gap?
Body Image: Four-Year-Olds 'Feeling Pressure'
Trend Watch: How Chatter Matters in TV Viewing
There is a chance that you are reading this post on a tablet or smartphone. In fact, you might even be dividing your attention between these words and a nearby TV or laptop. If that's the case, you are in good company.
According to an infographic created and sponsored by Uberflip, 81% of Americans use a smartphone and watch TV simultaneously. The biggest use of the second screen appears to be social networking, and watching TV, it's easy enough to see networks strive to make the connection.
Nearly every reality show has related hashtags flash by occasionally, encouraging viewers to weigh in on Twitter, which is the biggest drivers of social TV, with 33% of users tweeting about it last June. (via)
INFOGRAPHIC: 80 per cent of UK Twitter users log on via mobile
UK obsessed with TV and internet - Confused.com
Posted by Derek E. Baird on 02 March 2013 | Permalink | 0 Comments


Description: M W M Construction Ed Services is a business categorized under business consulting services, not elsewhere classified, which is part of the larger category business consulting services, not elsewhere classified. M W M Construction Ed Services is located at the address 7837 South Street in Oakdale, Illinois 62268-1913. The Principal is Michael McElligott who can be contacted at (618)329-5440.
Location & access map for "M W M Construction Ed Services"


The Drum Kit-Kit OCHO supports up to eight drum pads. (up from six with the DKK-AI) The Ocho is a great choice for both tinkerers and musicians.
This version of the OCHO come assembled! There is no soldering to do on the circuit board.
On board note assignment, expansion port, and hackable with the Arduino IDE, with digital pins to spare the DKK Ocho is an awesome and customizable MIDI controller.
Connect to a MIDI sampler, or directly to your computer using our free to download Serial-to-MIDI software solution, or a standard MIDI-USB interface.
The DKK Ocho has connections for up to 8 drum pads and has our Roadie (optional on the DKK AI) built in. This version comes with the circuit board fully built (like all of our drum kits, you get to make your own drum pads).
Screw terminals for the drum pad connections (makes connecting the drum pads easier).
Includes piezos for eight drum pads.
On board Din-5 MIDI-out jack (Use the DKK OCHO, with your other MIDI equipment).
FTDI compatible 90 degree pin header (makes it easy to re-program or use our Serial to MIDI software and your computer).
DC 2.1mm power jack (power the DKK OCHO while on the road).
Four corner mounting holes (Build the OCHO into a project box).
Power selector jumper. USB (via optional FTDI cable) or DC power jack.
Download: Serial - MIDI Converter: v2c for Macintosh This is our recommended version.
Download: Serial - MIDI Converter: v2c for Windows This is our recommended version.


Q: I feel like I am grieving my loved one who has been diagnosed with or is struggling with a mental illness. What can I do to learn more about the process? Where can I go for support?
A: Feelings of grief and loss are common, normal responses when a loved is diagnosed with a mental illness or when you see the struggle your family member encounters when dealing with symptoms and other challenges of illness. Everyone grieves differently and it's not unusual for members of the same family to have a variety of feelings and experiences. Some family members may find books on the grieving process helpful. Check our reading list for suggestions.
Other family members may find classes and support groups beneficial. The learning and advocacy section of our site provides information and links to local organizations offering classes, workshops and support groups.
Q: How do I get a diagnosis for myself or my family member?
Q: How do I get mental health services for myself or my family member?
Transporting your family member to the nearest Emergency Room is also an option if this can be done safely.
Q: How do I apply for financial assistance for myself or for my family member?
A: Many kinds of financial assistance (including those for food, medical insurance, housing, and general expenses) exist for individuals with disabilities, however, each has certain eligibility requirements and application processes. Ready to learn more about what's available, the eligibility requirements, and how you or your loved one can apply? Check the financial and basic needs assistance section of our definitions. You can also access the Hope For Recovery resource guide (PDF file) produced by the National Alliance on Mental Illness Minnesota providing information to families of individuals with mental illness. Financial assistance information begins on page 9 of this document.
Q: I'm trying to find information about a medication prescribed to me or my loved one. Where should I look?
Civil commitment is a legal process. Because it involves taking away a person's civil liberties and limits their rights in regard to mental and chemical health treatment, it is done only in rare circumstances. All efforts are made to treat people on a voluntary basis whenever possible. Learn more about civil commitment and initial steps to take when a loved one is in crisis.
Q: How do I apply for Social Security Disability Benefits for myself or a family member?


text:
March 7, 2011 / 8:20 PM / 8 years ago
Wimbledon to serve up 3D broadcasting this year
Martyn Herman
LONDON (Reuters) - Proud of its age-old traditions, Wimbledon has embraced the rapid changes in technology in recent years as smoothly as a Roger Federer forehand and now the world's most prestigious tennis tournament is going 3D.
Tomas Berdych of the Czech Republic hits a return to Serbia's Novak Djokovic during their men's semi-final match at the 2010 Wimbledon tennis championships in London, July 2, 2010 REUTERS/Toby Melville
Ian Ritchie, chief executive of the All England Club in the leafy suburbs of south west London since 2005, has presided over a stunning transformation of the grounds and Monday he announced that fans across the world would be able to watch this year's championships in 3D vision at home and in cinemas.
In partnership with Sony and host broadcaster the BBC, this year's men's singles semi-finals and men's and women's finals will be filmed in 3D and beamed to around 600 suitable cinemas around the globe as well as to national broadcasters.
While famous for its strict white clothing rules, strawberries and cream and ivy-clad balconies, Wimbledon has managed to move swiftly with the times.
Ritchie, whose background is in television, said that should come as no surprise.
"Starting way back, the first ever transmission in color the BBC put out was from Wimbledon so we were innovators then," he told Reuters Monday.
"Now there is an opportunity to expand into 3D broadcasts and it's very exciting. But as far as we are concerned it's that classic combination of tradition and innovation.
"Technically we like to be at the forefront of things and 3D is going to be a very interesting feature, not just for broadcasters but for cinemagoers around the world too," added Ritchie.
BUSIEST TIME
"Not everyone can be here during the championships so it's another opportunity for fans to feel a bit closer to the action.
"We see ourselves as the best tennis event in the world but we want to be seen as one of the best sporting events. If you stand still you fall behind."
Ritchie, responsible for securing multi-million pounds broadcasting deals with the BBC and American company NBC, is approaching his busiest time of the year with Wimbledon less than four months away.
A new addition for the 2011 tournament will be a Court Three showcourt — the completion of which concludes a 10-year improvement program that included a revamped Center Court complete with sliding roof, a new bull-ring type Court Two and the introduction of HawkEye technology.
Ritchie reeled off impressive statistics about 11 million hits on the tournament website last year and the launch of a smartphone application that has one million users.
However, while he welcomes the gizmos Ritchie is happy some things remain the same — at least until the Olympics take over the hallowed turf for a week in 2012.
"Yes, the white clothing rule will be relaxed and our strict advertising rules," he said. "They can wear multi-colored clothing, whatever they want to wear. It's their event.
"It will look quite different and it will be an interesting experience for the players because usually they just come here once a year but in 2012 they'll be back two weeks later. It will be interesting how they cope with that."
Editing by Tony Jimenez


Superfood Energy Bars. What you put in your body isn't the problem, it's the solution. This is the batting order of mother nature's all-star team. The best, purest, energy- giving, power-producing superfoods, vitamins and minerals. The hitters, the closers and the first super-group of plant-based nutrition–all gathered for you right here and now. Feel that? Yeah... now imagine putting a taste of that in the ole tank. Ba-boom. Must Read. 9g Protein. 11 Superfoods. 23 Vitamins + Minerals. 36mg natural caffeine. Certified gluten free. Non GMO. Kosher. Ancient grains. Minimally processed. No artificial colors or flavors. Soy free. Brown rice syrup free. Plant-based. Ethically sourced. If Mother Nature made anything better, she kept it for herself.
R.E.D.D. is pleased to announce that it recently secured $2.2 million of funding to help advance sales, marketing and R&D efforts.


text:
This document outlines all the steps and considerations for calling and merging
a trio using DeepVariant and [GLnexus](https://github.com/dnanexus-rnd/GLnexus).
These best practices were developed and evaluated as described in the article
published in _Bioinformatics_:
[Accurate, scalable cohort variant calls using DeepVariant and GLnexus](https://doi.org/10.1093/bioinformatics/btaa1081)
(2021).

The process involves 3 major stages: running DeepVariant to create individual
genome call sets, running GLnexus to merge call sets, and analyzing the merged
call set.

NOTE: This case study demonstrates an example of how to run DeepVariant
end-to-end on one machine. The steps below were done on a machine with this
[example command to start a machine](deepvariant-details.md#command-for-a-cpu-only-machine-on-google-cloud-platform).

The steps in this document can be extended to merge larger cohorts as well.

See this workflow:

![workflow](images/cohort-workflow.png?raw=true "DeepVariant+GLnexus cohort workflow")

A few things to note before we start:

*   It is recommended to use BAM files with original quality scores. In the case
    that BAM files went through recalibration, optional DV flags can be used in
    order to use original scores: `--parse_sam_aux_fields`,
    `--use_original_quality_scores`.
*   DeepVariant optionally allows gVCF output. This option is required for
    further GLnexus analysis in this document.

## Dataset

The Whole Exome Sequencing (WES) dataset we're using is from:

[ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/](https://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/)

*   HG002_NA24385_son
*   HG003_NA24149_father
*   HG004_NA24143_mother

### Commands for downloading the input BAMs

Just for convenience, we use aria2 to download our data. You can change it to
whatever other tools (wget, curl) that you prefer.

To install aria2, you can run: `sudo apt-get -y install aria2`

```
DIR="${PWD}/trio"
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/HG002_NA24385_son/OsloUniversityHospital_Exome/151002_7001448_0359_AC7F6GANXX_Sample_HG002-EEogPU_v02-KIT-Av5_AGATGTAC_L008.posiSrt.markDup.bam -o HG002.bam
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/HG002_NA24385_son/OsloUniversityHospital_Exome/151002_7001448_0359_AC7F6GANXX_Sample_HG002-EEogPU_v02-KIT-Av5_AGATGTAC_L008.posiSrt.markDup.bai -o HG002.bai
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/HG003_NA24149_father/OsloUniversityHospital_Exome/151002_7001448_0359_AC7F6GANXX_Sample_HG003-EEogPU_v02-KIT-Av5_TCTTCACA_L008.posiSrt.markDup.bam -o HG003.bam
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/HG003_NA24149_father/OsloUniversityHospital_Exome/151002_7001448_0359_AC7F6GANXX_Sample_HG003-EEogPU_v02-KIT-Av5_TCTTCACA_L008.posiSrt.markDup.bai -o HG003.bai
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/HG004_NA24143_mother/OsloUniversityHospital_Exome/151002_7001448_0359_AC7F6GANXX_Sample_HG004-EEogPU_v02-KIT-Av5_CCGAAGTA_L008.posiSrt.markDup.bam -o HG004.bam
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/data/AshkenazimTrio/HG004_NA24143_mother/OsloUniversityHospital_Exome/151002_7001448_0359_AC7F6GANXX_Sample_HG004-EEogPU_v02-KIT-Av5_CCGAAGTA_L008.posiSrt.markDup.bai -o HG004.bai
```

### Command for downloading the reference file

```
aria2c -c -x10 -s10 -d "${DIR}" https://storage.googleapis.com/deepvariant/exome-case-study-testdata/hs37d5.fa.gz
gunzip ${DIR}/hs37d5.fa.gz
aria2c -c -x10 -s10 -d "${DIR}" https://storage.googleapis.com/deepvariant/exome-case-study-testdata/hs37d5.fa.fai
```

### Command for downloading the input capture region BED file

```
aria2c -c -x10 -s10 -d "${DIR}" https://storage.googleapis.com/deepvariant/exome-case-study-testdata/agilent_sureselect_human_all_exon_v5_b37_targets.bed
```

### Command for downloading the truth files

HG002:

```
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG002_NA24385_son/NISTv4.2.1/GRCh37/HG002_GRCh37_1_22_v4.2.1_benchmark.vcf.gz -o HG002_truth.vcf.gz
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG002_NA24385_son/NISTv4.2.1/GRCh37/HG002_GRCh37_1_22_v4.2.1_benchmark.vcf.gz.tbi -o HG002_truth.vcf.gz.tbi
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG002_NA24385_son/NISTv4.2.1/GRCh37/HG002_GRCh37_1_22_v4.2.1_benchmark_noinconsistent.bed -o HG002_truth.bed
```

HG003:

```
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG003_NA24149_father/NISTv4.2.1/GRCh37/HG003_GRCh37_1_22_v4.2.1_benchmark.vcf.gz -o HG003_truth.vcf.gz
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG003_NA24149_father/NISTv4.2.1/GRCh37/HG003_GRCh37_1_22_v4.2.1_benchmark.vcf.gz.tbi -o HG003_truth.vcf.gz.tbi
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG003_NA24149_father/NISTv4.2.1/GRCh37/HG003_GRCh37_1_22_v4.2.1_benchmark_noinconsistent.bed -o HG003_truth.bed
```

HG004:

```
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG004_NA24143_mother/NISTv4.2.1/GRCh37/HG004_GRCh37_1_22_v4.2.1_benchmark.vcf.gz -o HG004_truth.vcf.gz
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG004_NA24143_mother/NISTv4.2.1/GRCh37/HG004_GRCh37_1_22_v4.2.1_benchmark.vcf.gz.tbi -o HG004_truth.vcf.gz.tbi
aria2c -c -x10 -s10 -d "${DIR}" ftp://ftp-trace.ncbi.nlm.nih.gov/giab/ftp/release/AshkenazimTrio/HG004_NA24143_mother/NISTv4.2.1/GRCh37/HG004_GRCh37_1_22_v4.2.1_benchmark_noinconsistent.bed -o HG004_truth.bed
```

(No need to install bcftools and other tools, because they are now installed in
the DeepVariant images.)

## Run DeepVariant on trio to get 3 single sample VCFs

First, install docker if you don't have it yet: `sudo apt-get -y install
docker.io`

With the example command below, it runs DeepVariant on the trio one by one. This
is for demonstration only. If you're running this on a large cohort, running
serially is not the most effective approach.

```
N_SHARDS=$(nproc)  # Or change to the number of cores you want to use
CAPTURE_BED=agilent_sureselect_human_all_exon_v5_b37_targets.bed
VERSION=1.4.0

declare -a trio=(HG002 HG003 HG004)
for SAMPLE in "${trio[@]}"
do
  BAM=${SAMPLE}.bam

  OUTPUT_VCF=${SAMPLE}.vcf.gz
  OUTPUT_GVCF=${SAMPLE}.g.vcf.gz

  time sudo docker run \
    -v "${DIR}":"/data" \
    google/deepvariant:${VERSION} \
    /opt/deepvariant/bin/run_deepvariant \
    --model_type=WES \
    --ref="/data/hs37d5.fa" \
    --reads="/data/${BAM}" \
    --regions="/data/${CAPTURE_BED}" \
    --output_vcf="/data/${OUTPUT_VCF}" \
    --output_gvcf="/data/${OUTPUT_GVCF}" \
    --num_shards=${N_SHARDS}
done
```

Note: The BAM files should provide unique names for each sample in their `SM`
header tag, which is usually derived from a command-line flag to the read
aligner. If your BAM files don't have unique `SM` tags (and if it's not feasible
to adjust the alignment pipeline), add the `--sample_name=XYZ` flag to
`run_deepvariant` to override the sample name written into the gVCF file header.

## Merge the trio samples using GLnexus

### Run GLnexus to merge 3 gVCFs

And then run GLnexus with this config:

```
sudo docker pull quay.io/mlin/glnexus:v1.2.7

time sudo docker run \
  -v "${DIR}":"/data" \
  quay.io/mlin/glnexus:v1.2.7 \
  /usr/local/bin/glnexus_cli \
  --config DeepVariantWES \
  --bed "/data/${CAPTURE_BED}" \
  /data/HG004.g.vcf.gz /data/HG003.g.vcf.gz /data/HG002.g.vcf.gz \
  | sudo docker run -i google/deepvariant:${VERSION} bcftools view - \
  | sudo docker run -i google/deepvariant:${VERSION} bgzip -c \
  > ${DIR}/deepvariant.cohort.vcf.gz
```

When we ran on this WES trio, it took only about 13 seconds. For more details on
performance, see
[GLnexus performance guide](https://github.com/dnanexus-rnd/GLnexus/wiki/Performance).

For a WGS cohort, we recommend using `--config DeepVariantWGS` instead of
`DeepVariantWES`. Another preset `DeepVariant_unfiltered` is available in
`glnexus:v1.2.7` or later versions for merging DeepVariant gVCFs with no QC
filters or genotype revision (see
[GitHub issue #326](https://github.com/google/deepvariant/issues/326) for a
potential use case). The details of these presets can be found
[here](../deepvariant/cohort_best_practice).

## Annotate the merged VCF with Mendelian discordance information using RTG Tools

Create an SDF template from our reference file:

```
sudo docker run \
  -v "${DIR}":"/data" \
  realtimegenomics/rtg-tools format \
  -o /data/hs37d5.sdf /data/hs37d5.fa
```

Create a PED file `$DIR/trio.ped` that looks like this (with the sample name
of the trio):

```
#PED format pedigree
#
#fam-id/ind-id/pat-id/mat-id: 0=unknown
#sex: 1=male; 2=female; 0=unknown
#phenotype: -9=missing, 0=missing; 1=unaffected; 2=affected
#
#fam-id ind-id pat-id mat-id sex phen
1 Sample_Diag-excap51-HG002-EEogPU Sample_Diag-excap51-HG003-EEogPU Sample_Diag-excap51-HG004-EEogPU 1 0
1 Sample_Diag-excap51-HG003-EEogPU 0 0 1 0
1 Sample_Diag-excap51-HG004-EEogPU 0 0 2 0
```

## Annotate merged VCF with RTG Tools

```
sudo docker run \
  -v "${DIR}":"/data" \
  realtimegenomics/rtg-tools mendelian \
  -i /data/deepvariant.cohort.vcf.gz \
  -o /data/deepvariant.annotated.vcf.gz \
  --pedigree=/data/trio.ped \
  -t /data/hs37d5.sdf \
  | tee ${DIR}/deepvariant.input_rtg_output.txt
```

The output is:

```
Checking: /data/deepvariant.cohort.vcf.gz
Family: [Sample_Diag-excap51-HG003-EEogPU + Sample_Diag-excap51-HG004-EEogPU] -> [Sample_Diag-excap51-HG002-EEogPU]
Concordance Sample_Diag-excap51-HG002-EEogPU: F:56909/57378 (99.18%)  M:57287/57388 (99.82%)  F+M:56726/57304 (98.99%)
Sample Sample_Diag-excap51-HG002-EEogPU has less than 99.0 concordance with both parents. Check for incorrect pedigree or sample mislabelling.
810/57551 (1.41%) records did not conform to expected call ploidy
57481/57551 (99.88%) records were variant in at least 1 family member and checked for Mendelian constraints
139/57481 (0.24%) records had indeterminate consistency status due to incomplete calls
586/57481 (1.02%) records contained a violation of Mendelian constraints
```

From this report, we know that there is a 1.02% Mendelian violation rate, and
0.24% of the records had incomplete calls (with `.`) so RTG couldn't determine
whether there is violation or not.

## Single sample quality metrics

In addition to the cohort quality statistics, for completeness we generate
single-sample quality metrics.

### ti/tv ratio

We run `bcftools stats` on the 3 VCF outputs. Since our DeepVariant run already
constrained to just the capture regions, no need to specify it again here. We
had to pass in the `-f PASS` flag so that only the PASS calls are considered.

```
declare -a trio=(HG002 HG003 HG004)
for SAMPLE in "${trio[@]}"
do
  sudo docker run \
  -v ${DIR}:${DIR} \
  google/deepvariant:${VERSION} \
  bcftools stats -f PASS \
    ${DIR}/${SAMPLE}.vcf.gz \
  > ${DIR}/${SAMPLE}.stats
done
```

| Sample | [3]ts | [4]tv | [5]ts/tv | [6]ts (1st ALT) | [7]tv (1st ALT) | [8]ts/tv (1st ALT) |
| ------ | ----- | ----- | -------- | --------------- | --------------- | ------------------ |
| HG002  | 29865 | 11620 | 2.57     | 29852           | 11597           | 2.57               |
| HG003  | 29725 | 11684 | 2.54     | 29715           | 11664           | 2.55               |
| HG004  | 29977 | 11774 | 2.55     | 29967           | 11759           | 2.55               |

If you want to restrict to the truth BED files, use this command:

```
declare -a trio=(HG002 HG003 HG004)
for SAMPLE in "${trio[@]}"
do
  sudo docker run \
  -v ${DIR}:${DIR} \
  google/deepvariant:${VERSION} \
  bcftools stats -f PASS \
    -T ${DIR}/${SAMPLE}_truth.bed \
    ${DIR}/${SAMPLE}.vcf.gz \
  > ${DIR}/${SAMPLE}.with_truth_bed.stats
done
```

Which resulted in this table:

| Sample | [3]ts | [4]tv | [5]ts/tv | [6]ts (1st ALT) | [7]tv (1st ALT) | [8]ts/tv (1st ALT) |
| ------ | ----- | ----- | -------- | --------------- | --------------- | ------------------ |
| HG002  | 27700 | 10532 | 2.63     | 27692           | 10519           | 2.63               |
| HG003  | 27355 | 10508 | 2.60     | 27351           | 10497           | 2.61               |
| HG004  | 27487 | 10594 | 2.59     | 27480           | 10584           | 2.60               |

### Rtg vcfstats

```
declare -a trio=(HG002 HG003 HG004)
for SAMPLE in "${trio[@]}"
do
  sudo docker run \
  -v "${DIR}":"/data" \
  realtimegenomics/rtg-tools vcfstats \
  /data/${SAMPLE}.vcf.gz \
  > ${DIR}/${SAMPLE}.vcfstats
done
```

which shows the following:

HG002:

```
Location                     : /data/HG002.vcf.gz
Failed Filters               : 14791
Passed Filters               : 45065
SNPs                         : 41450
MNPs                         : 0
Insertions                   : 1845
Deletions                    : 1747
Indels                       : 19
Same as reference            : 4
SNP Transitions/Transversions: 2.57 (41757/16262)
Total Het/Hom ratio          : 1.48 (26926/18135)
SNP Het/Hom ratio            : 1.51 (24904/16546)
MNP Het/Hom ratio            : - (0/0)
Insertion Het/Hom ratio      : 1.06 (951/894)
Deletion Het/Hom ratio       : 1.51 (1052/695)
Indel Het/Hom ratio          : - (19/0)
Insertion/Deletion ratio     : 1.06 (1845/1747)
Indel/SNP+MNP ratio          : 0.09 (3611/41450)
```

HG003:

```
Location                     : /data/HG003.vcf.gz
Failed Filters               : 15639
Passed Filters               : 44934
SNPs                         : 41376
MNPs                         : 0
Insertions                   : 1831
Deletions                    : 1705
Indels                       : 20
Same as reference            : 2
SNP Transitions/Transversions: 2.52 (41551/16483)
Total Het/Hom ratio          : 1.47 (26741/18191)
SNP Het/Hom ratio            : 1.49 (24738/16638)
MNP Het/Hom ratio            : - (0/0)
Insertion Het/Hom ratio      : 1.10 (960/871)
Deletion Het/Hom ratio       : 1.50 (1023/682)
Indel Het/Hom ratio          : - (20/0)
Insertion/Deletion ratio     : 1.07 (1831/1705)
Indel/SNP+MNP ratio          : 0.09 (3556/41376)
```

HG004:

```
Location                     : /data/HG004.vcf.gz
Failed Filters               : 15362
Passed Filters               : 45319
SNPs                         : 41724
MNPs                         : 0
Insertions                   : 1852
Deletions                    : 1720
Indels                       : 19
Same as reference            : 4
SNP Transitions/Transversions: 2.56 (41594/16279)
Total Het/Hom ratio          : 1.56 (27637/17678)
SNP Het/Hom ratio            : 1.59 (25594/16130)
MNP Het/Hom ratio            : - (0/0)
Insertion Het/Hom ratio      : 1.12 (979/873)
Deletion Het/Hom ratio       : 1.55 (1045/675)
Indel Het/Hom ratio          : - (19/0)
Insertion/Deletion ratio     : 1.08 (1852/1720)
Indel/SNP+MNP ratio          : 0.09 (3591/41724)
```

### Run hap.py to calculate the accuracy of DeepVariant generated call sets

```
sudo docker pull jmcdani20/hap.py:v0.3.12

declare -a trio=(HG002 HG003 HG004)
for SAMPLE in "${trio[@]}"
do
  sudo docker run -i \
    -v "${DIR}":"/data" \
    jmcdani20/hap.py:v0.3.12 /opt/hap.py/bin/hap.py \
    "/data/${SAMPLE}_truth.vcf.gz" \
    "/data/${SAMPLE}.vcf.gz" \
    -f "/data/${SAMPLE}_truth.bed" \
    -T "/data/${CAPTURE_BED}" \
    -r "/data/hs37d5.fa" \
    -o "/data/${SAMPLE}.happy.output" \
    --engine=vcfeval \
    --pass-only > ${DIR}/${SAMPLE}.stdout
done
```

Accuracy F1 scores:

Sample | Indel    | SNP
------ | -------- | --------
HG002  | 0.974142 | 0.993779
HG003  | 0.966972 | 0.993778
HG004  | 0.972279 | 0.993899

redpajama_set_name: RedPajamaGithub


text:
Amendment 1 supporters to rally ahead of session
They want legislators to use the money for land and water conservation.
Amendment 1 supporters to rally ahead of session They want legislators to use the money for land and water conservation. Check out this story on tallahassee.com: http://on.tdo.com/1DBZWZm
Sean Rossman, Democrat staff writer Published 1:27 p.m. ET Feb. 3, 2015 | Updated 10:44 a.m. ET Feb. 4, 2015
Wakulla Springs(Photo: Mike Schwarz)
The sponsors of the water and land conservation provision Amendment 1 are gathering for a rally and lobby day at the Florida Capitol later this month ahead of what is likely to be a contentious legislative debate over the use of environmental dollars.
Supporters will come from across the state on Feb. 18 to get "pumped" on Amendment 1, said Aliki Moncrief, director of Florida's Water and Land, the coalition that campaigned to pass the amendment.
In November, voters overwhelmingly passed Amendment 1, which will set aside millions of dollars from a real estate tax for the Land Acquisition Trust Fund within the Florida Department of Environmental Protection. That money will be directed toward improving land and water, including wetlands, forests and fish and wildlife habitat.
Hundreds of supporters will hold a two-hour rally then present talking points to lawmakers, who will decide how the money should be spent.
There is already disagreement over how the money should be used.
Last week, Agriculture Commissioner Adam Putnam argued that in some cases the money could be used for municipal sewer and water projects. Tallahassee Mayor Andrew Gillum has said he wants the city to receive Amendment 1 funds to get rid of septic tanks in the southern section of the city.
Moncrief and other Amendment 1 supporters say such programs were not what voters intended. Rather, the money should be used to pay for existing environmental programs such as Florida Forever and Everglades and springs restoration.
Moncrief hopes lobbying efforts will convince lawmakers about the importance of those existing programs.
"Let's make sure that we're educating them and pointing towards the success stories in our own districts," Moncrief said.
The legislative jostling around Amendment 1 has already begun. On Friday, Sen. Charlie Dean, R-Inverness, filed six bills that would designate a trust fund within DEP to handle Amendment 1 money. The bills would also eliminate existing trust funds that benefit environmental programs. Those programs would then be eligible for financing from the new fund.
Dean is chairman of the Senate Committee on Environmental Preservation and Conservation, which has received 4,385 online public comments concerning Amendment 1.
Moncrief said she and her staff are still analyzing the bills. The proposed legislation appears to be structural bills, she said, and do not affect Amendment 1.
Eric Draper, executive director of Florida Audubon, said he has not made up his mind on whether it was a good idea to eliminate the different trust funds but understands why they decided to take that approach.
"I'm comfortable with what the Senate has done," Draper said. "It puts that voter-approved Land Acquisition Trust Fund right in the center of the process and that's a good thing. The purposes of the trust funds are kept under the bills."
The News Service of Florida contributed to this article.
Read or Share this story: http://on.tdo.com/1DBZWZm


"Today we're sharing an update that will go into effect on July 13, 2016: we're banning ads for payday loans and some related products from our ads systems. We will no longer allow ads for loans where repayment is due within 60 days of the date of issue.
Many in the short-term online lending industry were surprised by the announcement, which seems to be in lock-step with the current administration's Operation Choke Point, an initiative launched in 2013 by the United States Department of Justice, whose stated intent was to "attack Internet, telemarketing, mail, and other mass market fraud against consumers, by choking fraudsters' access to the banking system." Critics of the program say it was used to put the financial squeeze on entire industries such as firearms sellers and payday lenders.
20 April, 2016: Google sign on the wall of the Google office building.
After all, there are many payday loan companies out there with bad reputations, and for good reasons: exorbitant interest upwards of 700% APR, hidden fees, confusing terms, poor customer service, misleading advertising, and overly aggressive collections practices, are a few examples of the kinds of bad behavior Operation Chokepoint is trying to eliminate. But the (perhaps) unintended consequence is that the ever-increasing regulations make it more and more difficult for newer lenders, including those like Wise Loan, who have a different point of view on the right way to lend, to offer its services.
The fact is, higher interest loans exist for a reason. In a recent study by the CFED (Corporation for Enterprise Development, http://assetsandopportunity.org/assets/pdf/2015_Scorecard_Report.pdf), it's estimated that around 56% of Americans have subprime credit scores, which means that when the average American walks into a bank looking for a loan, more than half of them won't get it. Having lower than average credit doesn't stop the average American from needing cash from time to time, such as for emergency short-term needs like having a car repaired, hospital bills, or other unforeseen needs.
So, does Google really think payday loans and other high interest loans are a bad idea?
Except that it still allows PPC advertising for other harmful industries, like online gambling.
Except that Google invested directly in Lending Club, and Google Ventures invested in LendUp, both leading online lenders.
Except that the most lasting and obvious result of the ban is that it will advance the market for established lenders because it makes the barrier to entry for new companies extremely high by removing the ability to buy advertising, and increasing reliance on Search Engine Optimization to attract new customers, which gives these more recognizable lenders an indisputable hand up.
Whatever Google's actual intentions, the ban isn't going to stop high interest lending, but established companies may benefit from an increased market share. And it isn't going to put the bad players out of business, but it might make it harder for consumers to find them.
Here at Wise Loan, we will simply to keep doing what we do best: provide loans in a friendly and efficient way that provides our customers with the funds they need in a way that they can afford, reward good repayment history with lower rates over time, report positive payment history, give our customers cashback in the form of our NestEgg savings program for every dollar repaid on time, develop customer tools for financial education and literacy, and continue to seek out new technology to improve our offering and lower costs over time.


text:
Amazon Sets March 17 Premiere for Spring 2017 Pilot Lineup
Posted Thu Mar 2, 2017 at 10:15 AM PST by Steven Cohen
Five new pilots will debut on Amazon later this month.
Amazon has revealed its upcoming Spring 2017 pilot lineup. 'The Legend of Master Legend,' 'Budding Prospects,' 'The New V.I.P.'s,' 'The Marvelous Mrs. Maisel,' and 'Oasis' are all set to premiere through Amazon Video in the US, UK, Germany, Austria, and Japan on March 17. After watching, all viewers will then have the option to review the shows in order to help Amazon decide which titles get picked up for full seasons.
"Pilots continue to be the best way to take risks, find voices and evolve the art form of television," said Joe Lewis, Head of Comedy, Drama & VR, Amazon Studios. "We're excited about these new worlds, characters and filmmakers. We're looking forward to another Amazon Pilot Season and more great customer feedback."
The Legend of Master Legend - The Legend of Master Legend is a dark comedy about the life of Frank Lafount, aka Master Legend -- a homemade superhero whose mission is to protect the people of Las Vegas from evil doers. Master Legend juggles the demands of justice with the even more complicated demands of his real family, who don't see him as a hero at all. The Legend of Master Legend is executive produced by Youree Henley (20th Century Women), Joshuah Bearman (Argo) and David Klawans (Argo), along with executive producers and writers Micah Fitzerman-Blue (Transparent) and Noah Harpster (Transparent). The pilot is directed by James Ponsoldt (The Spectacular Now) and stars John Hawkes (Winter's Bone), Dawnn Lewis (Major Crimes), Shea Whigham (Boardwalk Empire) and newcomer Anjelika Washington.
Budding Prospects -In 1983, three hapless city boys move from their comfort zone of the San Francisco counter-culture to Mendacino to grow marijuana. Their expectations of the experience being a back-to-the-land, nurturing adventure in a beautiful rustic setting run up against the harsh truth prior to their arrival at "The Summer Camp" – a miserably run-down shanty out in the middle of nowhere, where they are bedeviled by rats, snakes, mosquitoes, and harsh, unfriendly growing conditions, noisy neighbors, dangerous locals, and menacing law enforcement. Budding Prospects is directed and executive produced by Terry Zwigoff (Bad Santa), executive produced by Vincent Landay (Her) and co-written by Melissa Axelrod. The pilot stars Adam Rose (Veronica Mars), Joel David Moore (Bones), Will Sasso (MADtv) and Brett Gelman (Fleabag).
The New V.I.P.'s - Amazon's first adult animated comedy show, The New V.I.P.'s follows a group of low level employees who seize control of a major corporation after accidently murdering their boss. The show was created by Steve Dildarian (The Life & Times of Tim), Titmouse served as the production company (Ben Kalina and Dave Newberg), along with producer Peter Principato (Central Intelligence) from Principato Young. The pilot stars Matt Braunger (Agent Carter), Ben Schwartz (Parks and Recreation), Missi Pyle (Gone Girl) and Jonathan Adams (Last Man Standing).
The Marvelous Mrs. Maisel - The Marvelous Mrs. Maisel is written and directed by Amy Sherman-Palladino (Gilmore Girls) and executive produced by Daniel Palladino (Family Guy) and Sherman-Palladino. It's 1958 Manhattan and Miriam "Midge" Maisel (Rachel Brosnahan, House of Cards) has everything she's ever wanted—the perfect husband, two kids, and an elegant Upper West Side apartment perfect for hosting Yom Kippur dinner. But her perfect life suddenly takes an unexpected turn and Midge discovers a previously unknown talent—one that changes her life forever. She charts a course that takes her from her comfortable life on Riverside Drive, through the basket houses and nightclubs of Greenwich Village as she storms the world of stand-up comedy…a course that will ultimately lead her to a spot on Johnny Carson's couch. The Marvelous Mrs. Maisel also stars Michael Zegen (Boardwalk Empire) as Midge's husband Joel Maisel, Alex Borstein (Family Guy) as Susie Myerson, Golden Globe winner and three-time Emmy Winner Tony Shalhoub (Monk) as Midge's father Abe Weinberg, and Marin Hinkle (Two and a Half Men) as Midge's mother Rose Weinberg.
Oasis - Based on the cult-hit novel The Book of Strange New Things from Michel Faber, Oasis follows a chaplain (Richard Madden, Game of Thrones) who is sent into space to help establish a colony on a distant planet. What he ends up discovering not only puts his faith to the test, but life as we know it. The pilot also stars world-renowned Indian actor and producer Anil Kapoor (Slumdog Millionaire, 24) as Vikram Danesh, the head of the base on Oasis, Michael Shaw (Limitless) as B.G., Antje Traue (Man of Steel) as Grainger, Mark Addy (Game of Thrones) as Halloran, Haley Joel Osment (The Sixth Sense, Alpha House) as Sy, Maureen Sebastian (American Gothic) as Alicia Ruiz, Michael Shaffer (Coach Sinclair) as Phelps, and Zawe Ashton (Nocturnal Animals) as Severin. Oasis is written by Matt Charman (Bridge of Spies), executive produced by Charman, Andy Harries (The Crown) and Lila Rawlings (Left Bank Productions), produced by Rob Bullock (The Night Manager), with Kevin MacDonald (The Last King of Scotland) directing. The one-hour drama pilot is a co-production of Amazon Studios and Left Bank Productions.
A current Amazon Prime subscription costs $99 per year or $11 per month. Likewise, Prime Instant Video is available as a standalone service for $9 per month.
See what people are saying about this story in our forums area, or check out other recent discussions.
The Legend of Master Legend
Budding Prospects
The New V.I.P.'s