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On the Menu: Nutrients' role in preventing Alzheimer's
Nutritional supplementation may help reduce the incidence of dementia, but more research is needed
Tue, Mar 25, 2014, 01:00
Paula Mee
Alzheimer's disease: A recent Behaviour & Attitudes survey among a representative sample of 700 Irish adults (aged 50 years and over) revealed that a third of respondents believed a diagnosis of Alzheimer's disease would be significantly more difficult to cope with than one of heart disease. Photograph: Getty Images
With an ageing world population and improvements in healthcare systems, more people will be diagnosed with chronic disease, including dementia.
This global epidemic can no longer be ignored and neglected, according to Alzheimer's Disease International (ADI), a worldwide federation of Alzheimer associations. Currently, 44 million people worldwide live with dementia.
However, the future forecast is startling. It is estimated that by 2050 this figure will rise to 135 million. With one new case occurring every four seconds, dementia should be considered a public health priority in all countries.
Typically chronic and progressive by nature, dementia alters our ability to think, recall and behave. Performing everyday activities becomes challenging and often people face their worst fear – they lose their independence. This is not a normal part of ageing.
Brain diseases
Dementia is caused by a number of different brain diseases, one of which is Alzheimer's disease.
A recent Behaviour & Attitudes survey among a representative sample of 700 Irish adults (aged 50 years and over) revealed that a third of respondents believed a diagnosis of Alzheimer's disease would be significantly more difficult to cope with than one of heart disease.
The survey confirmed strong levels of fear, stigma and uncertainty associated with the disease.
Nearly half of respondents believed that they would have to give up their careers if they were diagnosed with the early symptoms of the disease.
The majority said they would wait a number of months to see a GP if they noticed they were suffering from memory loss.
Getting older and having a family history of Alzheimer's disease increase our risk of developing the disease.
It is also thought that modifiable lifestyle-related factors such as high blood pressure, high cholesterol levels, obesity and type 2 diabetes in midlife can increase our risk too.
Although the pathophysiology of Alzheimer's disease is complex, there are three main characteristics of the condition – beta amyloid plaque formation, neurofibrillary tangles and the loss of brain synapses.
Amyloid plaques are found in the spaces between nerve cells and are a normal part of ageing. However, in Alzheimer's disease they develop in cognitive areas and affect brain function.
Neurons in brain cells have an internal support structure partly made up of microtubules. A protein called tau helps stabilise microtubules.
In Alzheimer's disease, tau changes, causing microtubules to collapse, and tau proteins clump together to form neurofibrillary tangles which interfere with brain function.
Lastly, the brain consists of billions of specialised neurones which communicate with each other through synapses. In Alzheimer's disease, these synapses are damaged and lost, impairing brain function.
This loss of synapses is one of the key features of Alzheimer's disease in the early stages and is associated with memory loss.
Evidence shows that people in the early stages of the disease have a reduced capacity to make use of certain nutrients such as uridine monophosphate (UMP), choline, and docosahexaenoic acid (DHA), all of which are needed to replenish synapses lost due to the disease.
A review of available research carried out by the ADI confirmed that when folate or vitamin B12 is deficient, homocysteine levels rise. High homocysteine levels are linked to an increased risk of cardiovascular disease.
There is also consistent evidence that high levels of homocysteine are associated with cognitive decline. Nutritional screening carried out by a qualified dietitian can help identify malnutrition and those at risk of deficiencies in B12 and in folate.
Research shows they have lower levels of key nutrients, including omega-3 fatty acids, B vitamins, and vitamins C and E, when compared with age-matched individuals without Alzheimer's disease.
ent requirement
Patients may also have increased requirements for the nutrients like selenium.
Souvenaid is the first medical nutrition product designed to support synapse formation in early Alzheimer's disease. This 125ml drink, produced by Nutricia Medical, was launched in April 2013. It includes omega-3 polyunsaturated fatty acids, uridine and choline, together with phospholipids and B vitamins.
These nutrients are naturally present in food, although the levels found in Souvenaid are difficult to achieve from diet alone.
Souvenaid must be used under medical supervision and it has been shown in a small number of clinical trials to improve episodic memory at this stage of the disease.
The trials indicated that taking Souvenaid once a day over 24 weeks improved the memory performance of people in the early stages of Alzheimer's disease, as measured by functional tests of memory compared with the placebo group.
It may be particularly useful to those whose symptoms prevent them having a nutritionally adequate diet.
The Alzheimer's Disease International emphasises in its report, Nutrition and Dementia , published in February 2014, the need for clear, consistent and independent evidence-based advice to support decision-making as to the suitability of nutritional supplements for those at risk of, or already living with, dementia.
It calls for more research into the following:
n The possibility that nutritional supplementation may be effective in reducing the incidence of dementia in people who are deficient in certain B vitamins such as vitamin B12 and folate.
n The effective components of a Mediterranean diet with respect to the prevention of dementia and progression of Mild Cognitive Impairment.
n The possibility that some forms of supplementation may yet be effective in altering the course of dementia, if targeted upon those who are deficient.
n The minimum effective dose of vitamin E as a treatment for clinical progression in dementia, and the balance of associated risks and benefits.
Paula Mee is lead dietitian in Medfit and a member of the Irish Nutrition and Dietetic Institute. Email pmee@medfit.ie or tweet @paula_mee
Maureen Gaffney: The land of the mother and baby homes
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Kitchens and bathrooms see more renovations than any other room in a home. When it's time to embark on a change in your Boston area home, first consider the latest bathroom and kitchen renovation trends. Modern options may give you inspiration or turn out to be just the thing that offers a significant improvement to your home and your family's specific needs.
High-quality, commercial-grade appliances are being installed more often. These sturdy and efficient appliances, including refrigerators and ovens, are durable, energy efficient and convenient.
Bronze and copper fixtures are taking the place of the usual stainless steel or chrome. Touchless faucets are also getting more attention this year.
Quartz and quartzite kitchen countertops will continue to be popular choices, sometimes more popular than granite.
Grey paints and finishes are taking over as basic options, replacing beige and other neutral colors. Metallic options offer a way to add even more visually interesting highlights.
Strong and sturdy under-mounted enameled cast iron sinks are increasing popularity as a clean-up station. These sinks are durable enough to last for years.
As in the kitchen, touchless faucets and, specifically for bathrooms, touchless toilet fixtures are becoming more commonplace in new and renovated homes.
Bathtubs are becoming less popular as many homeowners opt for a larger and more luxurious shower space.
Radiant floor heating is being installed in more bathrooms. This type of comfort system heats the floor, allowing heat to radiate upward. Both efficiency and comfort levels are improved.
LED lighting is gradually taking the place of incandescent and fluorescent lighting in bathroom renovations. LED fixtures are versatile and energy efficient while providing plenty of lighting for the room.
For more information on bathroom and kitchen renovation trends that are making their mark in 2015, turn to Sage Builders LLC. Our team of experienced design/build professionals provide residential clients in the Boston area with professional kitchen and bathroom renovation services.


1. The kittens turn to me for help, paws outstretched, eyes beseeching. I save them from the danger, despite my degenerative illness and other sundry obstacles. A local radio station interviews me, but takes my quotes out of context.
2. A man — a representative of a Japanese handbag concern — offers me the sum of one million American dollars to license my eyes for billboard reproductions. These billboards will line the streets of Tokyo, Kobe, and, if demand continues, Osaka.
3. The agent calls me — it's a go. I'm on the next plane, excited, aloof, disheveled. I turn down their free peanuts.
4. My car begins to advise me in various matters. At first, the advice is measured, intelligent, sound. But soon, the advice becomes erratic, dangerous, muddled. I bring this to the car's attention, but it cannot understand my tone. I reprogram the radio stations and the car normalizes.
6. I shoot reasonably well in the Olympic biathlon trials. Later, a colleague asks me if that was my name he saw in the Sports section of the USA Today. I stare at him blankly.
7. The menu unfolds below me, tall, gilded, foreboding. I am confused. The waiter tells me about the specials in phrases that drip with adjectives — I nod, but do not hear what he is saying.
8. The document is sent to me via the e-mail system in my office. I download the attachment, and wait for a moment while Microsoft Word opens it. I print it out, make a few handwritten comments and fax it to back to the sender. Then there is the waiting.
9. Carbon dioxide is expelled from my nostrils and mouth, as I repeatedly take in oxygen. This continues for several hours.


Take a look tonight at the Moon. What lunar phase do you observe? If you and your students want to learn more about the lunar phases before studying the night sky, we recommend: http://bit.ly/RShiwaay.
Observing the Moon night after night and either photographing the phase or drawing it, is a good way to understand the natural rhythm of the Moon, Sun, and Earth, but it doesn't explain why the phases occur. A simulation of the Moon traveling around Earth helps students of all ages understand the patterns. Two sites are suggested with the second the simplified version: http://astro.unl.edu/naap/lps/animations/lps.swf and http://bit.ly/RSmcgraw-hill.
With an online lunar phase calendar you and your students can discover the lunar phases for dates past, present, and future! Students love looking back in time and finding the phase of the Moon on their day of birth and looking forward in time to discover the phase of the Moon on a future birthday.
There are many lunar phase calendars available but a good one to try is: http://bit.ly/RSalmanac. The page opens to the current calendar; scroll down for past and future calendars.
Studying the Moon phases each night might awaken your curiosity about the Moon. One NASA website is devoted to Earth's Moon, http://moon.nasa.gov/home.cfm, where you can learn about the Moon, missions to the Moon, and how you can be involved in studying it as a citizen scientist.


I'm strangely tempted, but I have no idea what these are worth. I'm always very intrigued by very regular cars in bizarrely good condition, but I'm not sure how smart it would be to buy one. Shame about the torn seats, I'd be more tempted if I knew I could collector plate it. Oh and it's a 5 speed.


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Books, Printed Ephemera and Manuscripts
[John William Donaldson, philologist, classicist, and biblical scholar.] Autograph Memorandum, signed 'J. W. Donaldson', giving four 'reasons' why 'Hercules was the husband & not the purchased slave of Omphale'.
J. W. Donaldson [John William Donaldson] (1811-1861), philologist., classicist and biblical scholar [Sir Thomas Gery Cullum (1777-1855) of Hardwick House and his wife Lady Ann Cullum (1807-1875)]
Publication details:
No place [King Edward's School, Bury St Edmunds]. 2 April 1844.
See Donaldson's entry in the Oxford DNB, which states that he was 'greatly beloved by his friends, who included N. C. Thirlwall and W. H. Thompson. The diarist Henry Crabb Robinson spoke enthusiastically of the charm of his conversation.' 3pp, 16mo. Bifolium. In good condition, lightly aged, with minor traces of mount adhering to blank reverse of second leaf. No salutation or valediction, and the recipient is not named, but the item derives from the papers of Sir Thomas Gery Cullum and his wife Lady Anne Cullum, of Hardwick House. Donaldson was headmaster at nearby King Edward's School, Bury St Edmunds, between 1841 and 1855. (The ODNB states that he was 'active in the cultural life of Bury St Edmunds, where he greatly improved the Athenaeum'.) The document simply begins: 'That Hercules was the husband & not the purchased slave of Omphale appears from the following reasons.' Four numbered 'reasons' follow, covering twenty-four lines. The last reads: '(4) The spirit of the fable or allegory presumes that Hercules was the husand of Omphale – i.e. that Strength allied itself to Beauty, & yielded to the gentle influence of the fair sex: this is the view taken by Propertius, II, 9 (11), 17.' At the end he signs: 'J. W. Donaldson | 2 April 1844.'
CULLUM
EDWARD'S
philologist
Phone enquries
RICHARD M. FORD
RICHARD M. FORD LTD (ABA)
(Dr Richard Ford)
Antiquarian Bookseller
70 Chaucer Road,
London, W3 6DP.
e-mail: richardford@manuscripts.me

redpajama_set_name: RedPajamaCommonCrawl


March 2013 is chock full of Horror conventions with at least one convention taking place every weekend and all have Friday The 13th guests (For more on those shows, please visit our Events Page). With the Monster Mania show right around the corner in a little over a week, it is always fun to see who their last minute adds will be and it looks as though a fan favorite is on their way to New Jersey.
Last night Larry Zerner (Shelly, Friday The 13th Part 3) wrote on his Twitter account that he was joining the show: "It looks like I'll be a guest at @MonsterManiaCon next week. I hope I can meet @Michael_Rooker and @Laurie_Holden. #LoveWalkingDead". Larry is a really great guy and loves to interact with the fans, so this is great news for the Friday The 13th audience! He still has not been officially added on the Monster Mania website, but look for that to happen real soon.


The chefs debate about their favorite part of the turkey to eat.
Giada makes a Turkey Breast Porchetta, an Italian stuffed and roasted meat.
Bobby Flay makes his Spanish Cranberry Sparkling Martini for the holidays.
Ina brightens her holiday green beans with a sprinkle of lemony gremolata.
Alton's Brussels Sprouts with Pecans is a deliciously simple side dish.
The chefs discuss what uncommon vegetables are served at their table.
Food Network presents a LIVE two-hour special hosted by Alton Brown, featuring Thanksgiving cooking tips from Rachael Ray, Anne Burrell, Sunny Anderson, Melissa d'Arabian and Bobby Flay.


Dealerships are always trying to sell demonstrator cars (or 'demos'). A demo is a car that is driven by managers, salespeople or test driven by many prospective car buyers but are still technically and legally referred to as new.
Dealerships may tell you that the demo has been immaculately maintained, citing its use by a dealership executive. They may also say that you can get a far better deal on this demo than you would get on a brand new car.
Our advice is – beware.
Most dealerships offer customers a discount for purchasing a demo car, which may seem generous at first glance. However, our experience tells us that the selling price of a demonstrator car is often not much less than if you purchased the same vehicle brand new.
In some cases there is considerable mileage on a "new" demo car, which for some manufacturers, is subtracted from the mileage allotment of your 'factory warranty.' Many demos also have wear and tear that may not be noticeable when first looking at the car. For example, the tyres on a demo car will need to be changed a lot sooner than if you were to buy a brand new car.
When buying a demo car, often there is not much choice as the dealer will normally only have one or two demo models on the floor. That means when it comes to choosing things like colour, and interor etc.
All of this means that the demo suddenly doesn't seem so attractive.
Auto Advantage specialises in providing our customers with great discounts and deals on all makes and models. In fact, we guarantee to save you time, money and stress, so it's worth talking to us about how much we can save you on your next car.


Equipped with 7 x 10 W high-power LEDs, a beam angle of 30° and a repetition rate of 3000 Hz, the professional PAR Cameo CLPFLATPRO7 enables overwhelming RGBWA colour mixtures.
Thanks to the passive cooling concept, this extremely compact spotlight works absolutely noiselessly, making it ideal for applications with limited space where silent operation is required.
With 5 DMX modes, many features, integrated programs and a microphone for music control, the CLPFLATPRO7 generates a huge colour palette of soft pastel shades to rich, warm full colours.


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Study finds newborn baby smell is addictive
The smell of a newborn baby induces the same pleasure response as drugs and food, particularly for women who recently became moms.
Mon Sep 30, 2013 - 2:51 pm EDT Sat Jun 19, 2021 - 11:42 am EDT
MONTREAL, September 30, 2013 (LifeSiteNews.com) – Craving the smell of your newborn baby? Scientists at the University of Montreal can explain why. Researcher Johannes Frasnelli and an international team of scientists studied the brains of 30 women – 15 mothers who had given birth three to six weeks prior, and 15 who had never had babies – and found that especially for new moms, the smell of a newborn baby activates the same pleasure and reward centers in a woman's brain as drugs do for an addict, or food does for the hungry.
In other words, new babies really do smell good enough to eat – and good enough to create real physical cravings.
"What we have shown for the first time is that the odor of newborns, which is part of these signals, activates the neurological reward circuit in mothers," Frasnelli said in a press release announcing the study's publication. "These circuits may especially be activated when you eat while being very hungry, but also in a craving addict receiving his drug. It is in fact the sating of desire."
To study the neurological effects of new baby smell, Frasnelli and a team of scientists at the Technical University of Dresden in Germany performed magnetic resonance imaging (MRI) on the brains of 30 women as they sniffed pajamas that had been worn by newborn babies for their first two days of life. Half of the women studied were brand new mothers, while half were childless.
While both groups showed activation of the brain's dopaminergic system, or "reward center" in response to the scent of the babies, new moms got by far biggest boost. The smell of a newborn baby provides moms with a hit of dopamine, the brain's "pleasure chemical," therefore rewarding the mom who cuddles her baby close with strong feelings of positivity and well-being.
Click "like" if you want to end abortion!
"Not all odors trigger this reaction," said Frasnelli. "Only those associated with reward, such as food or satisfying a desire, cause this activation."
Frasnelli told NPR he thinks the physiological rewards tied to a baby's scent are what seal the bond between mothers and their babies despite the difficulty of the early days of parenting.
"[Y]ou're living your life as a couple, everything is going fine and all of the sudden you have this little human being in your life that is actually, if you look at it from an objective point of view, actually pretty annoying," said Frasnelli. "Everything the baby does is sleeping, crying, and other than that you have to change the diapers. Still, most of the parents say this is the most beautiful thing that ever happened to me. And so how does this work? And we think the sense of smell helps us to understand the mechanisms that make this very strong attachment."


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QUEER, PROGRESSIVE, POST-EVANGELICAL CHRISTIAN
To the Queer Kids
For queer kids, it's harder than most appreciate to find a safe space.
For those of us studying in Evangelical colleges, even primary and secondary private Christian schools, we're met with open hostility.
I'm one of you.
This is an experience few can understand and many belittle, and your peers' inability to empathize with your situation only adds to your pain. The emotional burden placed upon you time and time again by these same people is immense; most humans aren't asked on a regular basis to provide epistemic justification for their own existence. It hurts no matter the source.
Your family, your friends, your professors, your administrators, your pastors, the leaders pontificating in your space - it's suffocating. Somehow, your desire to love and be loved is a threat to the fabric of society. And you know that doesn't make sense. You know it's not fair.
So this is for you.
You, fellow member of the LGBTQIA+ family, are quietly advocating justice if only by breathing, scarred by those whose religion should prompt them to love, wounded by systems pitted against you whose aim is mischaracterized as "love", whose impact is far from it. You sit quietly in your classes, your chapel services, your social gatherings, jaded at the flagrant dehumanization emanating from self-righteous exclusivism.
It can be far too easy to forget who you really are and the worth you already possess. Self-affirmation isn't easy in the first place, far less so when few around you are willing to affirm you as you are. Feeling loved is particularly challenging when love, the generous and inclusive kind, is scarce.
With that being said, I want to remind you of a few things:
You are good.
If you have a Protestant Evangelical past - I'm sure we could swap some stories - you've spent much of your life internalizing a theology of inherent wrongness. You may know it as "original sin", and it probably did a number on your conception of self-worth. A whole lot of people over the years have ruminated on our imperfections extensively in books and sermons, conflating a potential for wrongness with wrongness as exclusively inherent.
Here's the thing: You possess an inherent goodness. You are not irreparably broken, nor are you an aberration in some idealistic created "order". The ancient Hebraic origin story in the text many of us call Genesis tells of a Divine Other speaking all that is into existence. Standing in stark contrast to contemporaneous origin stories in the Near East, this Divine Being uses Her voice to construct our universe, beginning with light and concluding with humanity. Yet, rather than follow the same pattern, She does something different: She forms us out of dirt and breathes into us, imparting splendor and worth in a uniquely powerful way.
Even a couple thousand years later, this story and its implications are pretty different, pretty - dare I say - progressive. It pulls us ahead of our time, away from dehumanizing prejudices that plague society, pulling us towards equity, justice, and the recognition that we have been called good. The Divine calls all that's been made, from the watercolors of a sunset to a black hole's distortion of space-time, good. The text doesn't say "perfect" - in reality, the original language means something akin to very good. God is emphatically pleased with you. Perhaps the act of seeing this deep, indwelling goodness is a step towards a more just and whole society.
You, made of interstellar dust and wonderfully complex in ways not yet given scientific articulation, are good. Your sexuality, your gender identity, your primary and secondary sex characteristics - they are all part of what makes you you and they are all very good. Nothing and no one can take that away.
You are not the one in need of change.
No matter how many times you hear it preached and taught by those granted the influence with which to do so, you - gay, lesbian, bisexual, trans, pansexual, asexual, gender nonconforming, intersex, and more - need not change who you are. Your sexuality, gender identity, and personal expression are themselves good and an outworking of how God has made you, and there is no need to capitulate to harmful rhetoric suggesting you must change. For most of us, we know change to mean repression and suppression - it's coded language whose product is trauma. Insofar as you experience "aliveness", you are experiencing the deep welling-up of God's goodness in your being.
Keep breathing, keep loving, and remember that the burden of change is not on you: If anyone seeks from you an epistemological defense for your existence and right to live, you have every right to say no. In no way do you owe that labor to anyone - it isn't on you.
When you hear others call you "sinful", attack your "lifestyle", and suggest you must repent for who you are, remember this: Those calling you out are themselves in need of change. To suggest you are anything less than the glory of God in all its diverse and creative expression is sinful and premised in a lifestyle whose fruit is injustice.
Oh, how it feels that way, and it may look that way from where you sit. While your story is entirely unique, there are others experiencing a similar form of pain, that familiar kind of rejection, walking a dark road in hopes of finding acceptance and wholeness. Your story with theirs forms part of a tapestry woven across a diverse experiential landscape.
In Evangelical and conservative universities around the world, students like yourself are awakening to their inherent light and fighting the darkness with each and every breath. This collective effort is given strength through community, and if you've not yet found it in person on your campus or in your home, reach out through online platforms. If you can, leverage databases to seek out an affirming spiritual community nearby where you can find critical support.
Twitter is a particularly great place to find affirming writers, advocates, podcasters, and the like. You'll quickly find you're not alone - your academic environment needn't be a silo. The internet, with its many faults, is where I was introduced to others like myself seeking space in toxic environments. Books can serve as another rewarding mental and emotional investment.
As long as you occupy space where your identity is considered other, you will be confronted with isolation; it's never an easy thing to fight. While it may be hard to believe, remind yourself of this: you are not alone. You never have been, and you never will be.
You are loved - wholly, completely, and unconditionally.
You may hear this a lot, and perhaps your mind recites these words when things get tough. But believing them? That's hard. Internalizing your value and beloved-ness is a battle you will fight for quite some time. If you were raised to believe in the wrongness of same-sex love or that your gender assignment is a static absolute, seeing past these strictures takes a lot of strength, a lot of support, and won't feel initially natural.
If I could go back a couple years, I'd walk into East 73-204 and find a lonely college sophomore sitting on his dorm bed, holding back tears in the midst of an existential struggle for self-acceptance. In hopes of speaking over his growing walls, I'd tell him that striving for "rightness" - his quest for the model for God, the world, and self that answered deep questions of identity and purpose - is a fruitless and exhausting endeavor. I'd remind him that epistemology doesn't work that way, and he won't be the one to answer two thousand years' worth of unanswered questions.
No, I would tell him something simple and likely frustrating to his sensibilities: You are loved without condition, without reservation, and without exclusion. If there's anything that lonely queer kid needed to know then, it was of a deeper worth and a deeper beloved-ness that was never premised on answers, but that celebrated the humanity in asking unanswerable questions.
Even now, it's hard to believe. But I have to remind myself: I am loved.
Though you may not always feel it nor believe it, you are loved in ways you could not imagine by people you may not even know. I believe you are loved by a God Whose Love is not bound by human conceptions of worth. You are loved beyond capitalistic, cisgendered, heteronormative, patriarchal value systems whose purpose is to commodify your dignity.
All of you - your identity, your particular form of expression, your crush on your classmate, your heartbreak, your longing for companionship - is loved.
There's no exception.
Nothing I've written here is particularly exciting nor original, but I certainly hope it's comforting. If you're walking through a lot of questions, doubt, and striving towards self-acceptance like I was and still am, the very best thing I could hope to achieve is comfort. Encouragement. And I think I may have even done that for myself.
Remember: You are so very good, and you're good just the way you are. You're not alone. And most of all? You are loved.
May we all lean into our beloved-ness.
Nathanial Totten Green March 28, 2018 lgbtq+, progressivism, college, evangelicalismComment
What Liberty University Taught Me
Nathanial Totten Green May 25, 2018 Liberty University, lgbtq+, story, christianity5 Comments
What Evangelical Colleges Can Do for Their LGBTQ+ Students
Nathanial Totten Green February 22, 2018 lgbtq+, progressivism, Liberty University, college
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text:
Words Ginger Rose Clark Photography Kasia Bobula
With a new more feminine diffusion line and a host of new stores Louise Markey is a busy woman. Also talks to the LF Markey founder about juggling two successful brands, motherhood and how her home of East London inspires her work.
Louise Markey has had a busy year. The fashion designer – known primarily for her bright, utilitarian, minimal designs under the brand of LF Markey, recently launched a second womenswear brand called Meadows, hired a whole bunch of staff and opened not one, but two shops. Safe to say, she's got plenty to keep her occupied. Keen to discuss this impressive growth spurt, I sit down with Markey one autumn morning.
In the warmth of her studio we perch at a cutting table which is covered in fabric swatches and samples. Her team works away in the background, the only noise being the clicking of a camera from an e-comm shoot, while a model slips past us in a LF Markey look for next season. It's now well over ten years since the first LF Markey designs saw the light – Markey started her eponymous label in 2008, but it was only a few years later that it truly took shape: 'At first it was kind of a hobby label and it was on a different kind of trajectory. 2014 is when I knuckled down and decided exactly what LF Markey was going to be and didn't stray off it.' Colourful utilitarian pieces became the brand's signature and continue to be the defining traits to this day: these have garnered the brand a loyal following of creative, practical women.
One year ago, Markey decided to launch her second label, Meadows: 'I launched Meadows from my own personal interest. I started getting drawn towards folk stuff, even though I never thought I would as I've always been quite utilitarian. Early on, we started adding a bit of that in to the LF Markey collection but it's just so different. It's like the exact polar opposite, so it just made sense to make it a whole separate line. It meant I wouldn't have to hold back and try to work it into the utilitarian look: I could just go full on.' The result of this decision is very much in evidence in the studio: a mere glance at the separate clothing rails laden respectively with Meadows and LF Markey styles is enough to realise the hugely different aesthetic of each brand. While LF Markey is minimal and all about boiler suits and slacks, Meadows gravitates around dresses and blouses that are defined by Victoriana influences, with plenty of prints and floral motifs. Although the processes in creating both lines are the same, the main difference lies in the detail, as Markey explains: 'Meadows is way more labour intensive in terms of prints and embroideries, which I'm doing myself because I enjoy that.'
Markey observes that in just one year Meadows has come a long way: 'It's going well, considering it's so new. It took years to get LF Markey to where Meadows already is. It's actually easier launching a second brand by a long, long way because we've already got all the factories, we've got the whole team and it's not a big collection. Meadows is kind of a capsule for the moment, but growing – so we can just slip it into our workload. (…) It can kind of piggy-back off LF Markey.' So, what's been the key to this success? Experience, as Markey observes: 'You don't make the same mistakes again.'
With the recent exciting developments, the team has grown in numbers which inevitably called for a larger space. The new company HQ is tucked down an East London street alongside London's ubiquitous railway arches, home to all kinds of businesses imaginable. No setting could be better suited: the LF Markey brand, like its younger sibling, Meadows, is very much born and bred in the area, as Markey points out: 'I'd definitely say it's a product of East London. Both of the labels actually. Even Meadows, which is probably less classic East London – I see people wearing Meadows round here.'
This part of the capital is Louise's stomping ground, and has been for years. She lives in Stoke Newington, the new studio is in Hackney Downs and her first LF Markey store opened on Dalston Lane in January 2019. Of the latter, she says: 'It was a really obvious to open a store in East London. The brand originally grew from word of mouth, that's why it's so localised.' This sentiment was backed up by solid statistics: 'People around here are our customers. We can tell from our e-comm that we are shipping to lots of people round here.' As a result, even though physical retail as a general rule is suffering, the store on Dalston Lane is doing really well. In fact, it's going better than expected: what was originally designed to be a mere promotional tool, 'To show the world what LF Markey is like', has become a success in its own right.
Yes, East Londoners love Markey's work but it is very much a two-way relationship. Markey's connection with the area runs deep and serves as a source of inspiration: 'People on the street inspire me every day. And although my partner is pushing for us to move to the countryside, I don't know if I could leave and still be the designer of the collection because I feel like I get so much inspiration from around me. I see what people are wearing.' She adds that it is about that first-hand experience: 'Yes, you've got the internet, you've got Instagram, things which we didn't used to have… but that is such a curated experience – it doesn't show you what someone is wearing to the gym.' Indeed, as those that wear the brand will know, LF Markey is very much grounded in the everyday: Markey designs for the people surrounding her, and for their lifestyles.
That being said, it's not all about East London. Markey recently opened a shop on Monmouth Street in Covent Garden, which caters to a completely different type of customer due to its location in a prime tourist spot and, even further afield, her aesthetic has won over a growing following in the US. In fact, when we meet she has just got back from a successful business trip to New York where she was meeting with press. She says: 'It kind of ticks along on its own over there. I really wanted to break into the market because of Brexit – I was so freaked out about the pound plummeting, so I felt we needed to hedge our bets.' While we still have yet to see what impact Brexit will have, the decision has already turned out to have been a canny move – both of Markey's brands are doing really well across the pond and are now stocked in stores across the country.
Markey has been in the UK for years. Yet, when she talks, there's a slight Australian twang that betrays her Ozzie roots. While she still feels Australian, she has become something of a Londoner: 'I still feel Australian but I now realise how English I am, especially when I got to America. I see how I compare.' England has rubbed off on her and she's now very much settled here, not least because, alongside growing LF Markey and Meadows, she's a mum. Being her own boss allows her to balance family life and work: 'My day's working pattern is super weird. I often leave the office after lunch but then I pick up the computer again at 8pm. I actually really love it – I'm happy to juggle my day like that.'
As many have experienced, running a fashion business isn't without its challenges. Yet Markey makes it seem so effortless (she shrugs off problematic hurdles like the Trump tariffs). From starting out with a hobby to running a rapidly growing business with two unique brands, it's evident that she has found a formula that works. Perhaps the key to this success is that both LF Markey and, more recently, Meadows have resonated with customers in London and beyond because they feel so very genuine, each in their own special way.
www.meadows-store.com
www.lfmarkey.com
Themes Brand Business Designer female designers Motherhood Women
Garden Of Desire
Boobs / Ester Keate
PeopleInterview
BeautyEditorial


Pictured: Dr Sarah Olson (Neurosurgeon, PA Hospital); Dr Amanda Dines (Executive Director, RBWH); Associate Professor Cliff Pollard (Board Member, Metro North Hospital and Health Service); Neil Singleton (Insurance Commissioner, MAIC); and Dr Merrilyn Banks (Executive Director, Research, RBWH).
More than 80 people attended the Jamieson Trauma Institute's (JTI) Brain Trauma Research Collaboration Workshop on Tuesday 4 September, to delve deeper into one of the major causes of lifelong disability and death worldwide.
The workshop featured snapshots of research and capability from the Queensland Trauma Data Warehouse; Queensland Brain Institute; RECOVER Injury Research Centre, University of Queensland (UQ); The Hopkins Centre; Brain Injury Rehabilitation Unit, Princess Alexandra (PA) Hospital; Lady Cilento Rehabilitation; Australian Defence Force; Gallipoli Medical Research Foundation; Queensland Centre for Medical Research; CSIRO; QIMR Berghofer Medical Research Institute; Centre for Advanced Imaging, UQ; and the Herston Imaging Research Facility.
Executive Director of Research at the Royal Brisbane and Women's Hospital (RBWH), Dr Merrilyn Banks, said the event was full of incredible researchers, sharing their united interest in traumatic brain injury.
Representatives from MAIC were joined by staff from the National Injury Insurance Scheme Queensland (NIISQ) to learn about emerging initiatives occurring in the brain injury space.
MAIC Insurance Commissioner and NIISQ CEO, Neil Singleton, was pleased to see such strong interest in the forum both in terms of attendance and the excellent and informative presentations.
"It was great to see everyone come together to collaborate and learn. We look forward to seeing the output of the forum and the opportunities for action – whether it involves prevention, treatment or rehabilitation".


text:
Historian Homepage
Home / Historian / Historical Periods / Modern / World / The Palestinians and British Perfidy: The Tragic Aftermath of the Balfour Declaration of 1917
The Palestinians and British Perfidy: The Tragic Aftermath of the Balfour Declaration of 1917
C.W.R. Long; reviewed by Trevor James, last updated: 12th December 2018
The Palestinians and British Perfidy: The Tragic Aftermath of the Balfour Declaration of 1917, C.W.R. Long, Sussex Academic Press, 2018, 307p, £75-00. ISBN 1845198961978.
One of the hazards of modern-day British politics, an experience shared by politicians in both of our main political parties, is to express a view or opinion on what might be described as the 'Palestinian problem'.
The title of Richard Long's book – The Palestinians and British Perfidy – may seem rather pejorative in tone, and therefore very controversial, but his by-line explains the direction of his thinking – The Tragic Aftermath of the Balfour Declaration of 1917. This book, therefore, takes us to the heart of the modern-day dilemma which confronts politicians and commentators on Palestinian issues.
In the late 19th Century there had been a widely held view that the provision of a Jewish national homeland would be a positive opportunity to offer to the various displaced Jewish communities around the world. Madagascar and the Argentine, for example, had been proposed in some quarters, and the Russians had actively considered the Crimea as a possible location. However, in the late 19th Century Jewish settlers, frequently refugees, had begun to arrive in Palestine, with the full understanding that they were, in effect, returning to their spiritual homeland.
With the collapse of the Ottoman Empire being a likely outcome of the Great War, consideration was being given to the future governance of the various elements of that Empire in what we might define as the Near and Middle East. In the midst of these deliberations, the Balfour Declaration of 1917 emerged.
The promise of a Jewish National Homeland in Palestine was not in itself a promise of a Jewish National State, but many of the Zionist participants in the settlement regarded that as their objective. The British, in being allocated the mandate for Palestine, had a strategic interest in that region because it was believed that control of Palestine was a valuable strategic alternative to the Suez Canal and Egypt, should other nationalists present a challenge to the British route to India. It was that sense that drove British policy until later on it became apparent that India was approaching independence and that, therefore, British interests there would cease.
Whilst these two parallel manoeuvres were being pursued, and the flow of Jewish settlers continued to grow, no one had fully addressed the issue of the approaching one million indigenous Arabs in Palestine and how they were to be embraced by either of these processes.
There is a persuasive coherence to Richard Long's analysis. What he does is to depict the chain of events which eventually led to the establishment of the State of Israel in 1948 and the beginnings of the still-to-be-resolved future of the indigenous Arab population.
This book is a valuable contribution to the debate on how to provide a positive future for the indigenous Palestinian people. It has been a challenge since 1948 and it continues to this day.
The Poisoned Well: Empire and its Legacy in the Middle East
Journeys Home: Indian forces and the First World War
The Northern Limit: Britain, Canada and Greenland, 1917-20
One Giant Leap – 50 years since the Apollo 11 Moon landing
Henry Matthews, Viscount Llandaff: The Unknown Home Secretary
24 Hours at Balaclava: 25 October 1854


The Wall Street Journal, citing anonymous individuals, reports that Google deliberately avoided disclosing the problem at the time, in part to avoid drawing regulatory scrutiny. "Earlier this year, right at the time they discovered this, the Facebook Cambridge Analytica data breach had just happened, there's a lot of regulator scrutiny of Facebook and tech companies and how they're handling data, and internally, they were anxious about being pulled into this conversation in a bigger way". After an internal committee had already reached the decision not to disclose the privacy and security issue to the public, Google's CEO, Sundar Pichai, was also notified. Despite this, they still plan to shut down Google+, providing people the next ten months to migrate their personal information.
Google learned in March that a software vulnerability that has existed in its Google+ service since 2015 could have allowed malicious third-party app developers to access users' private profile information.
Despite the social network closing down, you can still take action.
In addition to "sunsetting consumer Google+", the company is making changes to APIs on its other services, which will limit the amount of access developers get to data on Android and Gmail.
"Smith said that despite Google's engineering teams putting in a lot of effort, "[Google+] has not achieved broad consumer or developer adoption, and has seen limited user interaction with apps.
A spokeswoman for Google said that whenever user data may have been affected it determines whether to tell people based on a number of criteria.
This privacy breach, in addition to dwindling user numbers and engagement, has prompted the search giant to shutter the consumer side of Google+.
But the company kept it open long enough to cause an embarrassing privacy gaffe that could give Congress an excuse to enact tighter controls on data collection. That said, social media is the business where Google has failed to mark its presence.
A memo reviewed by the Journal prepared by Google's legal and policy staff and shared with senior executives warned that disclosing the incident would likely trigger "immediate regulatory interest" and invite comparisons to Facebook's leak of user information to data firm Cambridge Analytica. Google is also following from its limiting of Gmail scans by limiting which applications - namely, down to email apps - can do so. If an app wants access to a Calendar and Drive documents, for example, you can opt to share one but not the other.
Yes, Kane is still only 25 years old and has time on his side, but he will have his work cut out to get on Messi's level. Spurs fell behind after less than two minutes at Wembley and found themselves 2-0 down at the break.
The U.S. would "continue to fly , sail and operate anywhere worldwide law allows", said Gorman, the Pacific Fleet spokesman. The US said its plane was conducting routine operations in worldwide airspace, and called the incident an unsafe intercept.
It was Julen Lopetegui's first derby as Real coach, although he was the fifth Real manager Diego Simeone had stood opposite. Bale has also provided three assists, but Real will have to cope without him when they take on CSKA Moscow .
It is Trump's first time in Africa - visiting four countries in five days - and her first solo global trip as the first lady. She had pin-pointed promotion of child education, fight against HIV/AIDS and conservation as her pivotal areas of focus.
But if they really cared about a true investigation, Comey said there wouldn't be an alarm on the investigation. Adam Schiff (D-Calif.) wrote : "This is not how you conduct an investigation".
Melania Trump , the First Lady of the United States has this evening jetted into the country aboard Air force plane. On her trip, Trump has promoted the advocacy initiative " Be Best ", which she launched earlier this year.
Over rates had to do a bit with the umpires who were pushing us with these new rules coming in of drinking too much water. After Bhuvneshwar Kumar he is the second Indian to achieve the feat. "I couldn't have imagined my test debut like this".


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Asthma New Zealand provides a wide range of free education and support services to the community, asthma sufferers and their families.
Asthma New Zealand has leading edge technology to use in the fight to control asthma in New Zealand, raising awareness, educating and providing people with asthma the tools required to self-manage their symptoms and live life to the full.
At least one person in New Zealand dies every week from asthma. Asthma is the leading cause of hospitalisation for children in New Zealand, and every year - 550,000 school days are lost. The severity of asthma can be reduced with sufficient support, advice, and education along with the appropriate medication. COPD is the 4th leading cause of death in New Zealand.
Asthma New Zealand has leading edge technology to use in the fight to control asthma in New Zealand, raising awareness, educating, and providing people with asthma the tools required to self-manage their symptoms and live life to the full.
At least one person in New Zealand dies every week from asthma. The severity of asthma can be reduced with sufficient support, advice, and education along with the appropriate medication.
This organisation page was created on 17 Mar 2015.


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Q: Swift 4: How can I add a Countdown timer inside of my UIbutton .settitle? I am trying to add a Countdown timer inside of my UIButton in the .settitle. How can I do this? The image below is what I am trying to accomplish.

Then once the timer gets to 0, I want the background color to change to a different color.
Here is the code I have so far.
let sendSMSAgainNumberOfTime: UIButton = {
    let button = UIButton(type: .system)
    button.backgroundColor = .black
    button.layer.cornerRadius = 7
    button.setTitle("SEND SMS AGAIN IN 36", for: .normal)
    button.setTitleColor(.white, for: .normal)
    button.titleLabel?.font = UIFont(name: "open sans", size: 16)
    return button
}()

A: You can also do the following in Swift 5. This is a very simple countdown that prints each second remaining after button is tapped. Let me know if you have any questions (:
class ViewController: UIViewController {

    var secondsRemaining = 30

    @IBAction func startTimer(_ sender: UIButton) {

        Timer.scheduledTimer(withTimeInterval: 1.0, repeats: true) { (Timer) in
            if self.secondsRemaining > 0 {
                print ("\(self.secondsRemaining) seconds")
                self.secondsRemaining -= 1
            } else {
                self.invalidate()
            }
        }

    }

A: You can try a timer
 var countTimer:Timer!

 var counter = 36

//
in viewDidLoad set it
 self.countTimer = Timer.scheduledTimer(timeInterval: 1 ,
                                              target: self,
                                              selector: #selector(self.changeTitle),
                                              userInfo: nil,
                                              repeats: true)

func changeTitle()
{
     if counter != 0
     {
         button.setTitle("SEND SMS AGAIN IN \(counter)", for: .normal)
         counter -= 1
     }
     else
     {
          countTimer.invalidate()

          button.backgroundColor = // set any color
     }

}

//
OR use IOS 10+ timer block
//
let sendSMSAgainNumberOfTime: UIButton = {
    let button = UIButton(type: .system)
    button.backgroundColor = .black
    button.layer.cornerRadius = 7
    button.setTitle("SEND SMS AGAIN IN 36", for: .normal)
    button.setTitleColor(.white, for: .normal)
    button.titleLabel?.font = UIFont(name: "open sans", size: 16)

    // timer block exists from ios 10 +

    if #available(iOS 10.0, *) {

        Timer.scheduledTimer(withTimeInterval: 1, repeats: true, block: { (t) in

            if(button.tag != 37)
            {
                button.setTitle("SEND SMS AGAIN IN \(36-button.tag)", for: .normal)

                button.tag += 1
            }
            else
            {
                t.invalidate()

                button.backgroundColor = // set any color
            }

        })
    } else {
        // Fallback on earlier versions
    }

    return button
}()

redpajama_set_name: RedPajamaStackExchange


Five years ago, Anne Moser walked into a book-store and purchased the cookbook Tartine Bread by Chad Robertson. A native of Germany, Moser had recently moved to California and was working as a translator. Homesickness and hunger often go hand in hand, and Moser longed for the fresh-baked artisanal bread found in small bakeries throughout her home country. She couldn't find the bread she wanted — so she decided to make it herself. Her hobby quickly turned into full-blown addiction. Later this month, Moser and her husband, Robert, are opening their first bakery, Backhaus, in downtown San Mateo.
"I never thought that I could start my own bakery business, but became obsessed with baking," Moser explains. "I taught myself using books, blogs and a lot of trial and error. After about a year of baking for me and my husband as well as friends and family, I decided to give it a go and applied for a cottage food license." This type of license allows someone like Moser to operate a small culinary operation out of a private home. Moser sold her country sourdough at farmers markets in San Mateo and Burlingame, soon developing a cultlike following. As the demand for her baked goods grew, Moser needed a bigger oven. She became a member of Kitchen-town, a local incubator for food startups, and was able to build the Backhaus brand from there.
Backhaus also supplies bread to two local restaurants in San Mateo and hopes to add more clients with the opening of the bakery.
The Bay Area's first location of Danny Meyer's iconic New York burger joint, Shake Shack, is now open at Palo Alto's Stanford Shopping Center. Culinary director Mark Rosati worked with local producers like Manresa Bread and Dandelion Chocolate to craft custom frozen custard flavors. An exclusive burger, available nowhere else, is called the Golden State Double and features Angus beef, cheddar cheese, pickles, and smoked garlic mayo on a Tartine Bakery sweet potato bun. Enjoy this and all the Shake Shack classics like the bacon cheeseburger smokeshack, crispy fried portobello mushroom burger, and fried chicken breast burger with buttermilk herb mayo.
Shop for sustainable and fair trade clothing and accessories at the new boutique Aiken in Palo Alto's Town & Country Village. It's Aiken's fourth Bay Area boutique — you may be familiar with its sister stores in San Francisco and Berkeley (formerly known as Convert). Most of the items are made in America — think brands like Velvet, J Brand, Kato Denim, and Ilse Jacobsen, plus Aiken-branded items like men's organic T-shirts. Local bridal designer Amy Kuschel recently debuted a ready-to-wear line, and her new pieces can be found at the Palo Alto Aiken.
BottleShop, a wine bar that pours difficult-to-find labels, is now open in Redwood City. Grab a glass of California red from a small producer and enjoy it with a plate of cheese or charcuterie. Owners Kristie Marie and Zu Tarazi are huge Champagne lovers and have stocked their new spot with plenty of bubbly. BottleShop is also just that: a bottle shop where you can purchase wine to go. There's a club, too, with members receiving three bottles per month (for $75) of premium vintages and varietals that are meant to be sipped now. Cheers!


Jellyfish Leggings — 907 Clothing Co.
These leggings are so versatile and extremely comfortable! They're great for exercising, wearing by themselves, under a skirt, dressed up or just as another layer to keep warm. The hand drawn triple jellyfish design is a favorite! It is beautifully printed in turquoise.


1. With more than ten years experience in exporting hunting products.
Q:.Do you provide samples ?
A:Yes,sample can be provided,but you need pay the cost of sample and shipment.When the large goods the sample freight will return.
Q:What will be your lead time?
A:15-30 days for existing models; 30-45 days for new models.
Q: I have new designs, can you open moulds for us?
A:Yes, we have a professional designing team. Just remind that there will be a quantity requested.
Q:We never import from China, can you help us to arrange?
A:Sure. We have professional logistics teams as well. We can help customer to arrange the delivery.
If you have any demands or questions on our products or services please feel free to contact with us. We are devoted to providing support solutions to you with reasonable price and professional service.