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Eva Green, producers battle in UK court…
Pressure on Japan in Rugby World Cup opener against Russia
Latest Stories Sports
By Editor September 18, 2019 September 18, 2019
The public awareness campaign has gone into overdrive at the Rugby World Cup, with Japanese Prime Minister Shinzo Abe getting a close look at the Webb Ellis Cup and receiving the red-and-white jersey of the national team from captain Michael Leitch.
And the public response has been big, with a reported 15,000 people attending a practice session for the Welsh squad, and the New Zealand All Blacks being swamped with fans.
Leitch's Japan lineup will have its first genuine taste of the expectation which comes with being host when it plays Russia on Friday in the opening match of the first Rugby World Cup to be held in Asia.
An upset win over South Africa at the 2015 World Cup swelled Japan's fan-base at home and abroad and has added to the expectation that they may be the giant-killers of this year's tournament.
Backrower Leitch was one of eight players selected Wednesday in Japan's match-day 23 who were involved in that game four years ago.
Yu Tamara, a replacement four years ago, was picked by coach Jamie Joseph to start at flyhalf against Russia. Luke Thompson was included on the bench and, at 38, could become the oldest player to represent Japan in the competition and the first to play in four World Cups.
Leitch says his players are happy to live with heightened pressure and have their sights firmly set on making the quarterfinals for the first time. An emphatic win by 10th-ranked Japan over 20th-ranked Russia might help quiet the players' nerves and those of their fans while lauching the tournament on a high note.
Japan will have to be quickly into stride as it needs not only to beat Russia but to do so by a large margin if it is to have a chance of progressing to the knockout rounds. Points differential could come into play in deciding the top two teams in what seems to be an even pool.
Japan shares the group with top-ranked Ireland, Scotland, Russia and former quarterfinalist Samoa. After Russia it plays plays Ireland, then Samoa, making its last pool match against Scotland a possibly decisive contest for second place if Ireland tops the pool as expected.
"We have prepared well for our goal of making the quarterfinals," Leitch said after his team's 41-7 loss to South Africa in its final World Cup warm-up. "We just want to play to our ability."
The loss to South Africa was not in any way indicative of Japan's comparative standing with Tier One nations or of any decline in its ability since the last World Cup. Coach Jamie Joseph used the match for experimentation and to adapt a game plan to those of its pool opponents.
"The biggest lesson for us is that when we make a small mistake against a Tier One team they will punish us and score points," Joseph said. "They kicked the ball and forced us into mistakes. Ireland and Scotland will play like that against us, so it's an area we need to work on."
Joseph is aware of the pressure that will be on his squad in the opening match and for the remainder of the World Cup, and is sure his team can cope.
"We are a well-prepared team both physically and mentally," he said. "We understand what our roles are, whether it's the coaching staff or the medical staff or the players. Everyone understands how important this event is going to be but none more than our staff and the players themselves. We want to make everyone proud."
One of the men under most pressure is flyhalf Yu Tamura. Tamura was a bench player at the last World Cup but now has the task of guiding Japan's attacking game.
"This is a game with 15 players," Tamura said. "It's the same for any country. Everyone has to do a good job and it's difficult to deal with it all alone. The stage is all set with the home fans behind us."
Russia may still be startled to find itself at the center of the spectacle of the World Cup's opening match. The Russians were lucky to qualify, doing so only after Romania was disqualified for fielding ineligible players.
Russia's warm-up form has not been impressive: it conceded 162 points including 24 tries in its last three matches. But captain Vasily Artemyev said those games allowed Russia to overcome some rustiness and promised his team would be better at the World Cup.
Russia was expected to announce its lineup later Wednesday.
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redpajama_set_name: RedPajamaCommonCrawl


Introduction: Immunodysregulation polyendocrinopathy enteropathy x-linked syndrome (IPEX) is characterized by systemic autoimmunity, typically beginning in the first year of life. Most commonly triad of symptoms of diarrhea, dermatitis and endocrinopathy is present.
Case report: Presentatlion of male patient, born with body weight 3840 grams and 10 points in Apgar scale. In 13th day of life vomitting and tachypnoe were noted and in laboratory tests hyperglycemia of 653 mg/dl (36.2 mmol/l) and ketoacidosis were reported. Patient was diagnosed with diabetes and treatment with continous insulin infusion by insulin pump was started. Antibodies typical for diabetes type 1 were negative. In 9th month of life boy was hospitalized in the Department of Pediatrics, Diabetology and Endocrinology in Gdansk, Poland and mutation in KCNJ11 gene was excluded, but autoimmune thyroiditis was diagnosed and L-tyroxin treatment was implemented. In 12th month of life patient was diagnosed with nephrotic syndrome resistant to steroids. Patient had also periodical skin lesions and diarrhea. According to clinical presentation IPEX syndrome was suspected, T regulatory cells levels were normal and sample for genetic test for FOXP3 mutations was sent. One month later patient was diagnosed with absence seizures. Brain MRI scans were normal, but anti-neuronal antibodies (ABA) were highly possitive. Also anti-tissue transglutaminase antibodies were possitive and gluten free diet was started. In molecular tests performer in Department of Clicial Genetic in Łódź mutation in FOXP3 was found. Patient had started immunosupresion and had bone marrow transpalantation performed in Medical University in Wroclaw, Poland at the age of 2 years.
Conclusion: Neonatal diabetes in male patient with negative test for most common genetic causes of neonatal diabetes can be first symptom of IPEX syndrome.


Each year "New Life Gospel International Ministries "holds medical/dental camps deep in the interior for tribal people and poor community that do not have easy access to medical help. We invite medical professionals to come and be His hand extended.
DONATIONS for providing free clinics, medicines and surgeries are welcome.
NEW LIFE GOSPEL INTERNATIONAL MINISTRIES is a 501(c)(3) nonprofit, Charitable Organization.


Arkansas Bride generates bright, bold bridal fashion for both classic and current modern brides.
Respect by Aretha Franklin: A tribute to the queen of soul and an absolute classic, no matter the season, this song transcends it all.
Find this Pin and more on Fashion Inspiration.
An 85mm Prime lens is a great choice for portrait photography.
Tim Walker is one of my absolute favorite photographers, and one of my latest obsessions is posing next to your own oversized portrait, so t.
Meghan stepped out in London to visit an animal charity she's now supporting as patron in a head-to-toe tonal look that we can't get enough of.
For me, it wasn't about having some over the top wedding, but about celebrating this new journey joining together as husband and wife.
... and the classic styles had socialites aflutter. We overheard whispers of "stunning," "major" and "absolute perfection" rippling through the front row.


The ultimate pinball project for you and the kids- the PinBox 3000 Cardboard Pinball Machine! This DIY kit of cardboard a die cut tabletop pinball is fully customizable. Comes with two complete flipper systems and play boards for interchanging game surfaces. Ideas included so you design your own play board. Tilt the future with the Pinbox 3000 Cardboard Pinball Machine!
Two PinBox 3000 Core Systems may be linked together for BattleMode.
Assembly and customization is required. No tools are necessary for assembly. Assembly time is 90 minutes per PinBox 3000 (the box says 40 minutes, but...). Ages 7 and up (but the box could say 10 and up for construction). Includes twelve sheets of punch-out parts with a bag containing box rivets, rubber bands, and 3 marbles.
Warning: Choking hazard. Not recommended for children under 3 years old.


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Home/WORLD/Audrey Hepburn's son reacts to news of Rooney Mara playing 'Breakfast at Tiffany's' star in biopic
Audrey Hepburn's son reacts to news of Rooney Mara playing 'Breakfast at Tiffany's' star in biopic
Audrey Hepburn's son is speaking out amid news that Rooney Mara is playing the late actress in a new biopic.
On Thursday, Variety confirmed that a film about the iconic actress starring the 36-year-old is in the works at Apple. Oscar-nominated director Luca Guadagnino of "Call Me by Your Name" fame is attached to the project with Mara producing. "The Giver" co-writer Michael Mitnick is also on board to write the script.
According to the outlet, the plot details are being kept under wraps. Puck was the first to report the news of the film.
"I was not aware of the project," Sean Hepburn Ferrer told Fox News Digital on Friday. "Rooney is a delight. Sounds like there is a lot of love there."
AUDREY HEPBURN'S SON ON HOW SHE COPED WITH CHILDHOOD FAMINE DURING WWII: 'HER DREAMS KEPT HER GOING'
Rooney Mara (left) is playing Audrey Hepburn (right) in a biopic.
Mara has been nominated for an Oscar twice – for 2011's "The Girl With the Dragon Tattoo" and 2015's "Carol." Most recently, she starred in Guillermo del Toro's "Nightmare Alley" with Bradley Cooper, Cate Blanchett, Toni Collette and Willem Dafoe.
As for Guadagnino, the Italian filmmaker co-created, co-wrote and directed the 2021 HBO miniseries "We Are Who We Are."
Hepburn, one of the most iconic stars of Hollywood's golden era, captivated audiences with films like "Breakfast at Tiffany's," "My Fair Lady," "Sabrina," and "Funny Face," among others. During the later years of her life, Hepburn traveled the world to raise money and awareness for UNICEF (United Nation's Children's Fund) as a goodwill ambassador. Between 1988 and 1992, she worked in some of the poorest communities of Africa, South America and Asia, helping children who suffered from malnutrition.
During her four-decade career, Hepburn earned EGOT status by winning an Emmy, Oscar, Tony and Grammy Award. The last was received posthumously. Hepburn received the Presidential Medal of Freedom in 1992. She passed away in 1993 at age 63 from cancer.
Sean Hepburn Ferrer with his mother Audrey Hepburn.
(Photo by Fotos International/Getty Images)
In late 2020, Hepburn Ferrer teamed up with his wife Karin to write a children's book titled "Little Audrey's Daydream," which explores her tumultuous childhood in Holland and how fantasies of a better future kept her hopeful during horrific times.
At the time, he told Fox News Digital that his favorite memory of the beloved matriarch was "anytime I made her laugh."
"… Whenever I would make her laugh, she would really laugh from her stomach," said the 62-year-old. "It's one of the greatest things you can take from any relationship if you can make someone laugh and give them that moment of sunshine."
"But there are many moments I think about," he continued. "I think about when she drove me to the airport and I left to do my first job. I was walking through security and when I turned around, there were tears coming down her face. As a parent and having been through it, I now understand. But I take great comfort in those moments when I simply made her laugh."
Audrey Hepburn captivated audiences with films like 'Breakfast at Tiffany's,' 'My Fair Lady,' 'Sabrina,' and 'Funny Face,' among others.
(Photo by Archive Photos/Getty Images)
Hepburn Ferrer said he hoped the book would shed light on "what a remarkable person she was."
"I want to continue telling her story," said Hepburn Ferrer. "We want to continue the work that she cared the most about. She was very proud of the fact that she was able to contribute and do something, especially for children."
"I don't think we can ever fill those shoes, but we're noticing little footsteps in telling her story," he shared. "I think this book is really a message of hope. A young girl during the war read fairy tales and dreamed of a better life. And when she finally achieved that, she gave back to the world. Somehow magically, the story being told is that there's healing in hope."
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The Lars Larson ShowThe Lars Larson Show
St. Cloud State Closing Down Sherburne Residence Hall
A long-time dorm at St. Cloud State University will be shutting down at the end of the semester.
Enrollment at SCSU Drops Again
Enrollment is down again at St. Cloud State University.
St. Cloud State University Selects New Provost
St. Cloud State University has selected a permanent provost. St. Cloud State President Robbyn Wacker has chosen Dan Gregory as the institution's next provost.
Chrissy Gaetke
DFL State Rep Wolgamott Talks Higher Ed and Transportation
State Representative Dan Wolgamott says the state needs to pick up more of the tab for higher education and create a sustainable funding mechanism for road and bridge projects.
SCTCC President Shares her Vision for the School's Future
For the first time since being selected as the new president of St. Cloud Technical and Community College, Annesa Cheek had the opportunity to outline her goals for the future of the institution.
St. Cloud Metro Hosts Over 1K Graduating Students
More than 1,000 students are expected to turn their tassels from right to left this month.
University of Minnesota Picks Sole Finalist for Next President
The University of Minnesota may soon have its first woman president, as they've picked Joan Gabel as the sole finalist to become the university's 17th president.
Richard Leguil
SCSU Hosts De-Stress With Pets Events Prior to Finals
Furry friends are helping St. Cloud State University students handle their stress as finals grow near.
St. Ben's to Host Annual Festival of Cultures Event
You can try new foods, listen to different styles of music and learn more about other cultures Saturday night in St. Joseph.
St. Ben's and St. John's Rank as Top Schools for Studying Abroad
The College of St. Benedict and St. John's University continues to be a top school for students looking to study abroad during their college careers.


Helmand or Helmund both: hĕl´mənd [key], river, c.700 mi (1,130 km) long, rising in the Hindu Kush Mts., NE Afghanistan and flowing generally SW to the Sistan basin, SW Afghanistan, where it helps form the Hamun-i-Helmand (Sistan Lake), a marshy lake that extends into Iran; longest river in Afghanistan. The Arghandab is its chief tributary. The Helmand's ancient irrigation and river-control system was destroyed by Jenghiz Khan (13th cent.) and Timur (14th cent.); the modern irrigation works are vital to both Iranians and Afghans, and in times of drought there are disputes over water rights. The Helmand Valley Authority extensively developed the region, improving irrigation and flood control. The name also occurs as Hilmand and Hirmand.


CeBIT 2014 - Presentation "The Roadmap for ATM Migration to Windows 7"
Join KAL CEO, Aravinda Korala, at this year's CeBIT conference in Hannover for a special seminar exploring what banks need to know to prepare their ATM networks for Windows 7.
This unique presentation will look at the complexities, strategies and costs ATM owners and deployers must consider when planning to migrate to Windows 7 in light of Microsoft's decision to end XP support on April 8. Mitigating strategies will also be discussed for banks that do not plan to migrate from Windows XP to Windows 7 before the deadline.
The seminar will be held in room 13/14, Conference Centre, Hannover Exhibition Grounds, on Wednesday, March 12th, 3-4pm.
Taking place from March 10-14, CeBIT is a leading international ICT event that sets the stage for the hottest industry trends and innovations.
Join us at Stand D30, Hall 12 for the duration of the event.


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Presidential Candidates Make Their Cases Before AIPAC
By Don Gonyea
Published March 22, 2016 at 4:57 AM PDT
DAVID GREENE, HOST:
The American Israel Public Affairs Committee, AIPAC, is the largest and most important Jewish lobbying organization in the United States. It's members are active, and when they fill a sports arena for their annual conference in Washington, presidential candidates also show up. And yesterday, much of the focus was on Donald Trump. Here's NPR national political correspondent Don Gonyea.
DON GONYEA, BYLINE: Donald Trump was working from a script and a teleprompter - something he rarely does at rallies.
DONALD TRUMP: But I didn't come here tonight to pander to you about Israel. That's what politicians do - all talk, no action. Believe me.
GONYEA: On each topic, he'd start with the prepared text before adding extra lines. There's the Iran nuclear deal. First, Trump said he'd dismantle it. Then he said he'd enforce it better than any deal has ever been enforced, adding...
TRUMP: I've studied this issue in great detail. I would say, actually, greater by far than anybody else. Believe me. Oh, believe me. And it's a bad deal.
GONYEA: Trump was also looking to clear up some confusion over his past statements that raise concern among Jewish voters. Call it damage control. He said he'd be neutral in Mideast peace negotiations, something Republicans simply don't say. Then there's his recent hesitation to endorse moving the U.S. Embassy from Tel Aviv to Jerusalem. Now...
TRUMP: We will move the American Embassy to the eternal capital of the Jewish people, Jerusalem.
GONYEA: And there was this.
TRUMP: Discussions have been swirling about an attempt to bring a Security Council resolution on terms of an eventual agreement between Israel and Palestine. Let me be clear; an agreement imposed by the United Nations would be a total and complete disaster.
GONYEA: Senator Ted Cruz followed Trump. He opened his speech with a jab at language used by Trump moments earlier. Trump had referred to negotiations between Israel and Palestine, when such talks are actually with the Palestinians. Here's Cruz.
TED CRUZ: I'm thrilled to be here with you today. And let me say at the outset - perhaps to the surprise of the previous speaker - Palestine has not existed since 1948.
GONYEA: Cruz's point - that Donald Trump simply doesn't know enough about these things to effectively handle them as president. Earlier in the day, former Secretary of State Hillary Clinton spoke. She too attacked Trump without actually mentioning his name. She referenced things like violence at campaign rallies, calls to deport millions of immigrants and a proposal to ban Muslims from entering the U.S.
HILLARY CLINTON: If you see bigotry, oppose it. If you see violence, condemn it. If you see a bully, stand up to him.
GONYEA: She's describing in part the scene at Trump's campaign rallies. But it was a more subdued and somewhat more scripted Trump in this venue. Don Gonyea, NPR News, Washington. Transcript provided by NPR, Copyright NPR.
Don Gonyea
You're most likely to find NPR's Don Gonyea on the road, in some battleground state looking for voters to sit with him at the local lunch spot, the VFW or union hall, at a campaign rally, or at their kitchen tables to tell him what's on their minds. Through countless such conversations over the course of the year, he gets a ground-level view of American elections. Gonyea is NPR's National Political Correspondent, a position he has held since 2010. His reports can be heard on all NPR News programs and at NPR.org. To hear his sound-rich stories is akin to riding in the passenger seat of his rental car, traveling through Iowa or South Carolina or Michigan or wherever, right along with him.
See stories by Don Gonyea


Alan Priddy's 10m RIB is now waiting for passage at Port Said after an easy run from Malta over the preceding two days.
Alan Priddy's 10m RIB is now waiting for passage at Port Said after an easy run from Malta over the preceding two days.
Good weather enabled the 900 miles to be logged in 48 hours 7 minutes, an average of 19 knots. But it wasn't quite fast enough to catch this morning's 0700 convoy through the Suez Canal and so the would-be circumnavigation record-breakers look as though they have a 24-hour delay on their hands.
Meantime, the local marina, tourism office and Rotary Club are laying on a welcome to provide some compensation.


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You are here:Opinion
A painful Para 55 process: Why do councils have design review panels if they ignore them?
27 November, 2017 By Wendy Perring
Source: DARCSTUDIO
Source:DARCSTUDIO
Ground Floor Plan
A frustrated Wendy Perring of PAD Studio questions the worth of expert panels following a post-appeal planning refusal for a 'country house clause' home in the South Downs National Park
Why are highly qualified, specialist design panels appointed to advise on, enhance and protect our built environment, being ignored by local authorities – particularly in Paragraph 55 applications, where permission hinges on the interpretation of exceptional quality or innovative design?
Faced with increasingly challenging social, economic and political conditions, local authority planning and urban development departments are turning to qualified and respected design professionals, design review panel and design advocates to offer informed and unbiased advice on the merits of architectural proposals across the country. Most hold the view that beauty is subjective; it is in the eye of the beholder. However, Alain de Botton famously argues that beauty in the built environment is in fact objective, measurable and not at all subjective.
The RIBA would agree, actively promoting the role of the design review panel, while London mayor Sadiq Khan would presumably also concur with de Botton, having recently appointed 50 architects and designers as design advocates, helping to ensure the highest standards in design are achieved in projects commissioned by the GLA. Many of these 50 accomplished architects and design professionals sit on other design review panels across the country, often voluntarily giving their time in the pursuit of the 'exceptional.' The notion of 'exceptional' is a prevalent theme in this debate. How can exceptional be quantified and what are the mystical ingredients for this tasty recipe?
NPPF Paragraph 55 (the 'country house clause') houses are a hot topic at present and manipulated computer generated images of these 'exceptional' schemes are commonplace in architectural magazines. Paragraph 55 is the holy grail for architects. It demands the very best, requiring that the 'exceptional' be achieved on a greenfield site, often in breathtakingly beautiful locations where normal planning legislation does not apply. This raises key questions: how can permission for these schemes be achieved in an already beautiful place, when building could be perceived as a destructive act; how can the beauty of a natural place be 'enhanced' through the placing of a manmade object when this appears contradictory? Furthermore, can architecture be objectively defined as 'exceptional', when this is so widely considered a subjective characteristic?
Over the last two years our practice travelled this Paragraph 55 journey. All the ingredients had been assembled: an enlightened and experienced client with a stunningly beautiful site in the South Downs National Park; a planning consultant (Hughes Planning LLP) with numerous successful Paragraph 55 applications to his name; an internationally recognised and award-winning engineer, Eckersley O'Callaghan; an established landscape consultant, Terra Firma; and professor Doug King – a pioneer in the field of sustainable design who advises the government on sustainability issues.
We invested more than 1,400 hours of design time in the pursuit of exceptional. A charrette was held at a local school of architecture to embrace the ideas of students and use the project as an educational tool. The project was reviewed twice by the South Downs Review Panel – the approach was debated, the virtues of the site and landscape setting deliberated and the qualities of beauty dissected at length, all in the name of critical reflection. The scheme was honed and tuned and resubmitted to the design review panel, who finally delivered the verdict that the scheme (in their view) 'had passed the point of justification in relation to Paragraph 55.'
Following a lengthy and difficult planning process, the local authority – the South Downs National Park Authority – ignored the panel's recommendation and refused planning. Of course, it could be argued that the design review panel had made a mistake, and that they had missed something. After all, beauty is subjective, is it not? But to take this stance infers that several award-winning architects, landscape architects and academics do not know what is exceptional. If we accept beauty is objective (perhaps why we spend so long in schools of architecture training in an appreciation of design and beauty), should the architect's view be a compulsory element within the planning system and legislated by the Planning Inspectorate?
Following the refusal, with the assistance of Hughes Planning (a specialist planning consultant experienced in Para 55 houses) and a planning barrister, a planning appeal was lodged. The process took many months and the upsetting verdict was finally delivered in autumn 2017; the appeal was dismissed. Whilst the inspector Graham Goulde said there was 'much to commend about the quality and innovative nature of the house's design', he could not allow it to be built in the proposed 'sensitive' national park location, arguing that any new development could not preserve or enhance it, regardless of high-quality design.
This case sets a dangerous precedent for future Paragraph 55 schemes
This case sets a dangerous precedent for future Paragraph 55 schemes. It stifles the original intent of Paragraph 55 to facilitate development of an isolated home in the countryside building on Britain's legacy of grand country houses and castles which enhance their setting. It may lead to similar refusals particularly within AONBs and National Parks, where the project is wrongfully perceived to destruct rather than enhance the natural landscape.
After such a convoluted and tortuous process, all the design team were understandably distressed at the final appeal decision. To have been so close to success and with the support of those whose recommendations should have been heeded by the inspectorate, the final decision felt particularly unjust. It has been a frustrating process for all those involved, particularly the client who has shown such an unwavering trust in both the team and the planning system – a true patron of architecture and the arts.
However, undeterred by the sometimes overwhelming challenges posed by Paragraph 55, architects still eagerly head off in pursuit of the 'exceptional' design, bolstered by their self-belief and shielded by their thickened skins. We are already working on another Paragraph 55 house elsewhere in the UK.
Parsonage Barn by Pad Studio
Parsonage Farm is positioned within a unique area of Outstanding Natural Beauty. The landscape is dominated by the geology in the form of the South Downs Hills.
The village of East Meon and many of the buildings surrounding the site have a strong connection to this landscape and geology in their use of the vernacular building material of flint. They are formed from the very stuff of the earth, and these materials have stood the test of time.
The proposed design that has evolved is not the normal established way of creating a house. It is a true interdisciplinary collaboration between the disciplines of structure, environment, landscape and architecture that have worked together to meet an identified need.
As our clients approach retirement they have identified that their living requirements are changing – they require a home in which they can live comfortably and sustainably for the next 20-30 years. The architectural design is innovative – it is a direct response to the landscape in which it is sited, not only in form that the building takes, but in the innovative interpretation of the vernacular language of the area.
The locally available materials and traditional construction methods of East Meon have been the starting point for the decisions made as to what this home is crafted from. The result is dwelling that has a unique architectural and structural form that enhances it's setting because the collaborative coming together of the design approach achieves a harmony in balance with nature.
PAD Studio
Hampshire Architects: 'Providing strategic advice is more relevant than ever'
15 December, 2015Bob Wallbridge
Bob Wallbridge, head of architecture at Hampshire County Council, on the growing role of public architects
Pad Studio reveals designs for £850k tennis pavilion
5 November, 2015Laura Mark
Hampshire's Pad Studio has submitted plans for this tennis pavilion on the coast at Canoe Lake, Portsmouth
PAD Studio completes £550,000 New Forest house
2 July, 2015Michaila Hancock
Hampshire-based PAD Studio has completed this two-storey home set within a woodland garden
Exbury Egg by PAD Studio
4 September, 2014Wendy Perring
Stephen Lawrence Prize shortlist: Exbury Egg by PAD Studio
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4 September, 2014Laura Mark
Denizen Works' Manser Medal-shortlisted house on Tiree has been named among the six projects vying for this year's Stephen Lawrence Prize
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23 July, 2014Laura Mark
[FIRST LOOK + DRAWINGS + PROJECT DATA] PAD Studio has revealed plans for this 158m2 eco-home in East Sussex
Pad Studio completes £100,000 Hampshire cottage retrofit
Hampshire-based Pad Studio has completed this £100,000 extension and refurbishment of a bed and breakfast in the New Forest
New practices: PAD Studio
10 February, 2014Laura Mark
The latest in a series of practice profiles looking at architects who have recently decided to go it alone either through choice or redundancy
PAD Studio scoops planning for £950,000 eco-home
22 January, 2014Laura Mark
[FIRST LOOK + PLANS + PROJECT DATA] Hampshire-based PAD Studio has won planning for this low-energy private house in the New Forest
Floating timber egg takes to the water
10 June, 2013Laura Mark
PAD Studio has completed a floating artist residence on the Beaulieu River, in the New Forest
Jonathan Braddick RIBA Chartered Architect11 December, 2017 4:49 pm
I entirely agree that that beauty in the built environment is in fact objective, measurable, and not at all subjective. However, as an architect and the manager of The Design Review Panel (www.designreviewpanel.co.uk), providing regular design review panel sessions across the south west, I do not feel that all local authorities are ignoring the advice of design review panels. It is important not to criticise the design review panel process generally, and therefore potentially damage it, because of a few local authorities that may not yet be giving the correct regard to the feedback of a design review panel.
The Design Review Panel (www.designreviewpanel.co.uk) has reviewed, and continues to review, many Para 55 projects (as well as many commercial and large scale housing projects) and our Panel has several examples in the last 18 months alone of Para 55 applications where engagement by the design team with our Panel, throughout the design and pre application process, has directly led to an approval being granted by the local authority. We also have many other examples of other project types that have gained approval, and have been improved, as a direct result of engaging with our Panel. We have very positive testimonials from applicants, architects, local authority development managers and case officers that concur with this assertion.
Across the south west we have found that most local authorities are extremely welcoming and supportive of the use of design review panels. In particular Plymouth City Council, Exeter City Council, North Devon Council, Mid Devon Council, West Somerset Council, BANES and Taunton Deane Borough Council all regularly refer projects to Design Review Panels and they should be applauded for their positive and proactive approach.
In order for the Design Review Panel process to be useful and meaningful to all parties (applicants, design teams and local authorities) it is vital that design teams engage with the DRP process at an early stage and on several occasions throughout the design process, and not simply try to use a Panel as a mechanism for obtaining approval for their designs once a design has been completed and or an application has been submitted; this very often results in the frustration being expressed in the above article.
The Design Review Panel process should be used as part of the design stage, not the decision making stage.
I feel the design review panel process is an extremely useful and valuable tool for local authorities, applicants and design teams, and its use should be encouraged. What would help to give the design review panel process significant weight would be for the Planning Inspectorate to begin to rely on the independent and expert feedback given by design review panels in their appeal decisions when considering issues of design.
Jonathan Braddick
The Design Review Panel - Panel Manager
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i hope no one of them will find me.
love's the funeral of hearts and an ode for cruelty.
How can anybody know whats best for me?
Yesterday showed me what you are.
You are nothing special, something anybody would forget after minutes you met.
You are dishonest and mendacious.
And I know, I never meant something to you.
I cried so much, but now I know that was in vain.
You have not a spark of decency.
y o u a r e n o t h i n g f o r m e.
You played our game your way. You think I have lost?
You lost the chance to get through with your problems.
Fortunately as a friend. Unfortunately as a lover.
It never was this way and now.
You know I will never turn my back on you.
They can't hurt me anymore.
We will play the game with our rules.
But we have something they have not.
I'm afraid to ask you these questions because I don't know if I want to know the answers.


text:
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304 Pages | 20 illus.
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Founding Friendships
Friendships between Men and Women in the Early American Republic
Cassandra A. Good
First book on Founding Fathers' friendships with women
One of the only historical studies of male/female friendship to have been written
Uses friendship as a frame for studying cultural history of early American Republic
Displaces marriage as the only important, fulfilling relationship between men and women
"When Harry Met Sally" is only the most iconic of popular American movies, books, and articles that pose the question of whether friendships between men and women are possible. In Founding Friendships, Cassandra A. Good shows that this question was embedded in and debated as far back as the birth of the American nation. Indeed, many of the nation's founding fathers had female friends but popular rhetoric held that these relationships were fraught with social danger, if not impossible.
Elite men and women formed loving, politically significant friendships in the early national period that were crucial to the individuals' lives as well as the formation of a new national political system, as Cassandra Good illuminates. Abigail Adams called her friend Thomas Jefferson "one of the choice ones on earth," while George Washington signed a letter to his friend Elizabeth Powel with the words "I am always Yours." Their emotionally rich language is often mistaken for romance, but by analyzing period letters, diaries, novels, and etiquette books, Good reveals that friendships between men and women were quite common. At a time when personal relationships were deeply political, these bonds offered both parties affection and practical assistance as well as exemplified republican values of choice, freedom, equality, and virtue. In so doing, these friendships embodied the core values of the new nation and represented a transitional moment in gender and culture.
Northern and Southern, famous and lesser known, the men and women examined in Founding Friendships offer a fresh look at how the founding generation defined and experienced friendship, love, gender, and power.
1. Three Stories of Friendship
2. Reading Friendship
3. Friends and Lovers
4. Propriety, Positioning, and the Public Face of Friendship
5. Friendly Letters
6. The Gifts of Friendship
7. The Power of Friendship
Cassandra A. Good, Assistant Professor of History, Marymount University
Cassandra Good serves as an Assistant Professor of History at Marymount University in Arlington, Virginia. She was formerly the Associate Editor of the Papers of James Monroe at the University of Mary Washington.
Winner of the Mary Jurich Nickliss Prize in U.S. Women's and/or Gender History from the Organization of American Historians
"Founding Friendships is a nuanced and insightful examination of both the personal significance and the political salience of what the playwright, poet, and politico Mercy Otis Warren termed 'the soft whispers of private friendship'" - Anya Jabour, Journal of American History
"Meticulously researched, clearly written, and fascinating ... It will inspire both more debate and more research on the hitherto-neglected topic of inter-gender friendships." - Virginia Magazine of History
"Of all the familial configurations of the founders, 'founding friends' is the most richly provocative. Employing an impressive array of primary sources, Cassandra Good uncovers a hitherto unexplored realm where women were at their most equal and their relationships with male friends represented the purest form of republican ideals. Founding Friendships is a dazzling debut and a major contribution to our knowledge of early national culture." - Catherine Allgor, author of A Perfect Union: Dolley Madison and the Creation of the American Nation
"This beautifully written and insightful study builds on studies of same-sex friendship and marital friendship by turning our attention to cross-sex non-marital friendships during the revolutionary period. Cassandra Good shows that friendships between men and women were common, highly valued, and at the same time feared by citizens of the new republic. She provides a nuanced analysis of the delicate balancing act that friends of the opposite sex had to achieve between what their relationships had to offer and the potential dangers that they posed. This book will fascinate anyone interested in the history of friendship, the family, gender relations, the social and political history of the early republic, and the history of emotions." - Richard Godbeer, author of The Overflowing of Friendship: Love between Men and the Creation of the American Republic
"Cassandra Good's Founding Friendships is a remarkable account of how friendships between men and women were critical to both the social and political fabric of the new nation. Good's work is an insightful analysis of the flow of power in these male/female relationships that could be threatening to the traditional understanding of a proper social order. Only in 'quiet conversations' could women convey their observations and political opinions. It is a story of the utmost importance to our understanding of the early nineteenth century." - Barbara Oberg, Princeton University
"A sensitively-drawn study packed with insights into how men and women understood and experienced their friendships with each other at a time of great social and political change. Founding Friendships is filled with very real people banging up against changing expectations as they navigated the period's highly politicized and thereby rocky social terrain." - Joanne B. Freeman, author of Affairs of Honor: National Politics in the New Republic
"beautifully written and insightful ... Good's book further expands our understanding of the tight interweave between personal and public relationships during this formative period of US history, showing the ways in which non-marital friendships between men and women could enrich private lives and also the political realm." - Richard Godbeer, Journal of Social History
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The Making of a Terrorist
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The Making of the American Creative Class
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Arts & Humanities > History > History by Period > Modern History (1700-1945)
Arts & Humanities > History > History of Gender & Sexuality
Arts & Humanities > History > Regional & National History > United States History > US Social History
Arts & Humanities > History > Regional & National History > United States History > US Colonial & Revolutionary History


The sixth international trade fair for laboratory technology, analysis, biotechnology, and diagnostics (Analytica Vietnam 2019) was officially launched yesterday in the Saigon Exhibition and Convention Center (SECC, sited in District 7 of Ho Chi Minh City).
The event, jointly held by the National Agency for Science and Technology Information (NASATI) and Messe Munchen Corporate, lasts until April 5.
Many state-of-the-art machines and devices are displayed in this exhibition, including liquid chromatography-quadrupole - time-of-flight mass spectrometry machine; energy-dispersive X-ray spectroscopy device; fourier-transform infrared spectroscopy machine Alpha II; automatic potentiometric titrator; automatic NPK fertilizer analysis system SAN++; OMNIS – a new integrated method to improve efficiency and effectiveness in modern laboratories.
Analytica Vietnam 2019 welcomes around 140 organizations from 15 nations worldwide like Germany, the US, Japan, England, France, Russia, the Republic of Korea, India, China.


Two studies out of Australia and Japan have underscored the safety and effectiveness for widely-used treatments mesothelioma symptoms and the cancer itself, further reinforcing them as effective 'gold standards' in a field with few true beacons of hope for mesothelioma patients. This means that late-stage mesothelioma patients can rely on indwelling pleural catheters to remedy pleural effusion with relative safety, while patients facing chemotherapy have further reason to hope for the effectiveness of Cisplatin-Alimta (pemetrexed) drug cocktails.
One of the most common and life-limiting symptoms for pleural mesothelioma patients is known as pleural effusion, a fluid buildup in the lining around the lungs. Left untreated, pleural effusion can trigger shortness of breath, severe chest pain, coughing, and other undesirable problems.
So far, the solution to pleural effusion has been either pleurodesis, which fuses the lining together in order to block fluid from building up, or installation of a catheter into the space in order to drain off the fluid. Since not all patients are candidates for the sometimes-risky pleurodesis procedure, the availability of catheters has proved to be an effective recourse for many, even if it carries its own risks.
The most serious risk associated with the so-called indwelling pleural catheters, or IPCs, has been considered to be the risk that the pleural mesothelioma will spread along the catheter pathway. Some studies indicate more than 6% of patients with IPCs will experience this problem.
A new Australian study, published in the journal Chest, indicates that, while the issue is still of clinical concern, the practical effects are mild and manageable. Symptoms tend to be mild, while the metastasized cancer tends to respond well to radiotherapeutic treatment.
The study looked at 107 patients who had either pleural mesothelioma or another pleural-effusion-causing metastatic cancer. According to the study results, metastatic cancer appeared in 10% of cases, 9 mesothelioma patients and 2 patients with other cancer. It generally appeared quite late, a median 280 days following catheter insertion, and the longer the elapsed time the greater the risk of mesothelioma at the cancer site.
However, palliative radiotherapy aimed at the metastatic mesothelioma was used with six of those subjects, and it was effective and well-tolerated. The symptoms were mild and the cancer responded well, and the radiotherapy was possible to administer without removing the catheter.
While 90 percent of mesothelioma patients will eventually develop pleural effusion which could make them a candidate for the catheter procedure, Japanese researchers have concluded the best way to help earlier-stage mesothelioma patients remains the popular combination of cisplatin with Alimta (pemetrexed).
Studying 30 consecutive pleural mesothelioma patients between July 2002 and December 2011, they found that 35% of the 17 Alimta and cisplatin-treated patients responded, while only 15% of the 13 Gemzar and cisplatin-treated patients responded to therapy. The long term results were also favorable: Alimta-treated patients had a longer median survival (a year and 7 months, vs about 10 months) and less frequent and less severe side effects.
Both Gemzar and Alimta are chemotherapy drugs marketed by the same firm, Eli Lilly and Company.


Somewhat overlong and not as incisive as it could be, Cobain: Montage of Heck is nonetheless a satisfying portrait of a troubled genius.
Cobain's turbulent story is told mostly through a collage of archive footage, audio snippets and kinetically-animated journal entries, brought vibrantly to life through punchy editing and some smart soundtrack choices.
The film's original footage comprises some undercooked interviews with Cobain's family and friends and – the real highlight – some cel-shaded sequences which imaginatively depict key events of his life.
There is much here for newcomers and casual admirers; however, ardent Cobain fans may be left wanting.
Cobain's music and his striking artwork coalesce to help us understand his mind – however the rest of this documentary plays it a little too safe to take us much further.
SYNOPSIS: The authorized documentary on the late musician Kurt Cobain, from his early childhood in Washington to the height of his fame with Nirvana and eventual downfall.


text:
Scott Johnson, Reporter/weekend anchor
Tags: Clay County, Traffic, News
Clay County considers which dirt roads to pave
County commissioners discuss spending $5 million to resurface, pave roads
CLAY COUNTY, Fla. – Clay County Board of Commissioners met Tuesday afternoon to discuss paving hundreds of miles of dirt roads, as well as roads that are falling into disrepair, especially in older neighborhoods such as Middleburg, Keystone Heights and Lake Asbury.
The goal is to have all roads smooth and paved, like the ones in the newer areas of Fleming Island and Oakleaf.
About 250 miles of roads in Clay County are still dirt, and another 120 miles are crumbling and could soon fail. The County Commission on Tuesday talked about what roads will get money first.
For many of the county's residents, being on a dirt road has become normal. On Indigo Circle in Middleburg, LaVelda Rupert has lived on an unpaved road since she moved there in 2000, waiting for asphalt that entire time.
"I guess we just watch and get grateful and hope ours is next. I've heard ours is next," Rupert said. "I hope so."
Rupert and her neighbors told News4Jax that they were thrilled to learn Indigo Circle is at the top of Clay County's list to get paved.
"That's great," George Doran said.
Doran won't have to wait as long as Rupert did. He closed on his house on Monday.
"That would be outstanding, having a paved road, for sure. I'm a city boy. My girlfriend is the country one. She likes the dirt roads. I think a paved road would be phenomenal," he said.
On Tuesday, the County Commission discussed providing $5 million to work on unpaved roads, but the vast majority of the money will go towards resurfacing paved roads that are crumbling.
"(We) have a lot of roads getting close to failing. If they get too close to deteriorating, we're going to have to rebuild the entire road. So what we're trying to do is concentrate on the maintenance on them first," said Commission Chairman Wayne Bolla.
Bolla said the board recently took a bus tour of the county, looking at the worst roads. He said newer neighborhoods, such as Oakleaf and Fleming Island, have newer roads, but everywhere else has roads that are decades old, or have remained dirt, which will cost a lot more to improve.
"To repave a dirt road takes a lot more in engineering and money than it does to do resurfacing first," Bolla said.
The commission's discussion is only about county roads. Larger roads such as U.S. 17 and Blanding Boulevard are kept up by the state.
For lists of the roads that the county is looking at resurfacing or paving, click here.
Specializes in Clay County issues, general assignment reporting and stories off the beaten path and anchors weekend evening newscasts.


If half of your plate isn't covered in something green, you may want to consider how your diet could be impacting your heart health. A recent study presented at the American Heart Association EPI/Lifestyle 2015 meeting has found that adopting a diet that focuses more on plant-based foods compared to animal-based foods can significantly lower your heart disease and stroke risk.
"A pro-vegetarian diet doesn't make absolute recommendations about specific nutrients. It focuses on increasing the proportion of plant-based foods relative to animal-based foods, which results in an improved nutritionally balanced diet," Dr. Camille Lassale, an epidemiologist at Imperial College London's School of Public Health, said in a statement.
Lassale and his colleagues gathered data on the eating and lifestyle habits of 451,256 Europeans from 1992 to 2004 using the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Participants were free of any chronic disease and ranged from 35 to 70 years old. The research team analyzed height, weight, food intake by way of food frequency surveys, physical activity and lifestyle habits, and causes of death.
Each participant was given their own score based on the food they consumed. Points were given to participants who ate from seven plant food groups: vegetables, fruit, beans, cereals, potatoes, nuts, and olives. Points were deducted from participants who ate from five animal food groups: meats, animal fats, eggs, fish, seafood, or dairy products. Researchers categorized each participant based on their score while accounting for gender, calorie intake, BMI, exercise, alcohol, and smoking status.
Participants who mostly adhered to a pro-vegetarian diet — 70 percent of food coming from plant sources — were 20 percent less likely to die from cardiovascular disease compared to those who only got 45 percent of their food from plant-based sources. Findings from the study are on par with the American Heart Association's heart-healthy diet, which includes fruits, vegetables, whole grains, legumes, beans, and nuts, low-fat dairy, beans, skinless poultry, and fish.
"Instead of drastic avoidance of animal-based foods, substituting some of the meat in your diet with plant-based sources may be a very simple, useful way to lower cardiovascular mortality," Lassale added.
Data collected by the Oxford Martin Programme on the Future of Food and the British Heart Foundation Centre suggest that meat-eaters are not only hurting their heart, but also the environment. Around 70 percent of rainforests in the Amazon have been destroyed to make room for land capable of raising livestock. Livestock farming accounts for 20 percent of greenhouse gas emissions from human-related activities.
Source: Beulens J, Van der Schouw Y, Lassale C, et al. Semi-veggie diet effectively lowers heart disease, stroke risk. American Heart Association Meeting Report Abstract 16. 2015.


AC Milan host Atalanta at San Siro on Sunday in a Serie A clash between two sides who are enduring indifferent starts to the season.
From their three league games so far, Milan have won one, drawn one and lost one. It has certainly not been the start that Gennaro Gattuso would have hoped to see from his side following another summer of change at San Siro, and the Italian will hope to see improvements this weekend.
Atalanta arrive in Milan just one place below their hosts on Sunday in 14th and level on points with their counterparts. Like the Rossoneri, Atalanta have struggled for consistency so far, losing twice in their first four Serie A games, with one win and one draw also chalked up.
Sunday's match is an opportunity for both sides to kickstart their stuttering early form and begin the catch up with those already breaking clear of them in the ascendancy in the table.
Milan's opening match of the campaign provided further evidence of how far off the top teams in Serie A the Rossoneri have fallen, as Gattuso's side slipped to a 3-2 defeat away to last season's runners-up Napoli.
They responded in a strong manner, however, with a 2-1 defeat of Roma the following week, courtesy of a 95th-minute winner from Patrick Cutrone. Their domestic progress has since been halted, however, as Milan were held to a 1-1 draw away to Cagliari.
A narrow 1-0 win over Dudelange in the Europa League on Thursday night got Milan back to winning ways, but also suggested that there is still much work to be done by Gattuso's side.
Atalanta, meanwhile, began their Serie A campaign in more positive fashion with an impressive 4-0 win over Frosinone before securing a hard-fought 3-3 draw away to Roma the following week.
A succession of defeats have followed, however, with back-to-back deficits to Cagliari and SPAL grinding Atalanta's momentum to a halt with 1-0 and 2-0 defeats respectively. Gian Piero Gasperini's side will be anxious to avoid a third successive defeat when they travel to the San Siro on Sunday.
If the previous meeting between the two sides is anything to go by, Sunday's match could prove to be another occasion full of big incidents.
In a dramatic encounter between Atalanta and Milan at the Stadio Atleti Azzurri d'Italia in May, the home side produced a stunning late equaliser from Andrea Masiello in the 92nd minute to cancel out Franck Kessie's opening goal on the hour mark as the teams drew 1-1.
The drama was not limited to the goals, however, as both sides had a player sent off. Rafael Toloi was dismissed for the home side in the second half, before Riccardo Montolivo saw red for Milan just over ten minutes later in the match.
Both sides will be seeking greater control over proceedings in search of a much-needed win on Sunday.
Having scored the winner as Milan beat Dudelange 1-0 in the Europa League on Thursday, summer signing Gonzalo Higuain will undoubtedly be the danger man for the home side on Sunday, with the Argentine star set to provide Milan's primary goal threat.
Atalanta have a known marksman of their own, however, in the form of Colombian striker Duvan Zapata, who will fancy his chances of using his physicality and experience to trouble an inconsistent Milan defence which has struggled for stability this season.
Considering that, the Luxembourg side did pretty well against AC Milan in their first Europa League group game.
The departure of Leonardo Bonucci has left Gattuso's defence short of leadership and composure, and Zapata will certainly have the chance to exploit any deficiencies at the heart of the home side's rearguard.
The central component of the away side's defence from last season has also moved on, however, as Mattia Caldara, who was on loan at Atalanta last term from Juventus, joined their opponents on Sunday from the champions during the summer as part of the deal which saw Bonucci return to Turin from Milan after one season at the San Siro.
In essence, Sunday's game could be decided by which side's main man up front is able to cause more damage to the opposition's weakened defence.
Milan's ranks will be shortened by three absences on Sunday, with Riccardo Montolivo the highest profile injury victim in Gattuso's side, while full backs Andrea Conti and Ivan Strinic are also sidelined for the weekend.
Atalanta, meanwhile, will travel to Milan short of one defensive option of their own, with centre back Marco Varnier absent. The 20-year-old is still recovering from a cruciate ligament rupture suffered in July.
Though both sides are in similar need of the win, the pressure on Milan to deliver a league victory will be greater as Gattuso's side look to push up in the table, and the home comforts of San Siro should see the Rossoneri take control of Sunday's match.
Gonzalo Higuain's goal in midweek should have provided added confidence that Milan have the necessary firepower to earn the three points, with defensive frailties the primary concern which must be rectified to secure a victory this weekend.


What financial options are available to support the transaction?
Typical outsourcing transactions involve a degree of asset transfer and/or transformation and result in a situation whereby earlier months' cash-flows are negative because most outsourcing clients want to minimise the financial and accounting impact of the transaction.
In several cases the asymmetrical credit rating of buyer and seller also provides an opportunity to arbitrage and reduce the total cost of the transaction.
Changing market, accounting and tax regulation can alternatively limit or fuel the value in various structured finance strategies in order to allow for the sale (or acquisition) of assets and a related set of operational services which may allow for the operational transformation to be accompanied by a switch from balance sheet assets to a range of operational services which, subject to the future Lease Project of the IFRS may or may not be accounted for as a long term asset/liability by the parties to the outsourcing contract.
We can provide innovative transaction financing – structuring and placement – which can positively impact the case for change in most scenarios in looking at an outsourcing transaction as a typical structured finance transaction. In that context Burnt Oak Partners will be looking first inter alia to the project as the source of financing. The obligation to perform (by the vendor) and the obligation to pay (by the client) plus any further source of transaction support will jointly and (generally) severally be the basis for the financing decisions by the lending community.


This past April, the Rome SDS was one of four brands selected to participate in the first annual Transworld Team Shoot Out. It was a week-long, resort-bound contest to make a short video and shoot photos. Rome teamed up with Big Bear Mountain and brought in Bjorn Leines, LNP, Marie-France Roy, Eiki Helgason and Will Lavigne to do the shredding. Over the course of a week, the crew spent seven days, or more accurately seven nights, filming a short shred flick called "A Hard Days Night". The film will be released exclusively through iTunes on July 27th 2009, in a package with the three other videos in the contest.
The Team Shoot Out was a "contest" of progression and creativity, through film, photography, and feature construction. Transworld Snowboarding invited four teams, paired them up with four separate mountains and gave each team seven days to build and seven days to shred and shoot. Each team had five riders, two filmers and one photographer. Once the brands submitted their films in early June, Transworld got together a panel of people they trust to pick the winner based on the creativity of the video and the photos.
You can get a sneak peak of the teaser for the Rome film now on Rome's Shred TV; and be sure to check back on July 27th to download the entire movie from iTunes.
Stay tuned to www.romesnowboards.com for more on the Team Shoot Out and the announcement of the winner on July 27th.


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This was a curiosity – a play within a play about a play. Much of what we witnessed started life as a radio play and the whole thing was set in a studio. This version was written by Joe Landry. It was inspired by and included Orson Welles' 1938 broadcast of The War of the Worlds which had been adapted (incredibly quickly) by Howard Koch from the original novel by H. G. Wells. So – the work of many hands and presented in the wrong medium, it could easily have plodded. It didn't. Far from it. The company, under Colin Lawrence's expert direction, gave us an evening that was vibrant, full of interest and excitement.
Koch's adaptation relocated the story to New Jersey and set it in 1939. It therefore touched on contemporary fears of invasion and the prospects of war. Many of its radio audience were convinced that what they were hearing was a real crisis unfolding in real time. The result was hysteria and confusion. One listener was sure she heard the radio telling her that the Germans were coming. Franklin D. Roosevelt was quoted as saying, "the only thing we have to fear is fear itself – nameless, unreasoning, unjustified terror … ". (This production took place during the visit of Donald Trump to the UK. I merely mention the fact).
We were in good hands from the start as Guy Marshall drew us into the story with considerable conviction. From then on it sometimes seemed as if we were in two places at once – both in the studio (a simple but perfectly judged design by Barry Brown) and at the very site of the danger itself. This was achieved by Mark Easterfield's subtle and clever lighting, by a very good sound design, and through the pace and conviction brought to the piece by a uniformly excellent cast. For example, when the crowds gathered in the studio, they at first reacted to the cues of the studio manager but then began to respond directly to the vivid description of the invasion as provided by a febrile and fully-engaged Guy Holmes.
Scenes were sometimes interrupted by sharply played commercials representing the American Dream and accompanied by a pin-point accurate jingle from Mike Milne.
Tim Drummond's performance as the charismatic genius Orson Welles was compelling. There's a moment at the end of the adaptation when he has to describe the destruction of the Martians. Although it's lucid enough, the scene is an undramatic one: we don't witness these significant events, we're told about them. It's a mark of Tim's success in the role that this long and difficult speech created a powerful listening silence in the Playroom on a hot Saturday night in July.
This was a production to remember – and one on which to ponder.


Tribunals, Courts and Enforcement Act 2007, Section 39 is up to date with all changes known to be in force on or before 25 April 2019. There are changes that may be brought into force at a future date. Changes that have been made appear in the content and are referenced with annotations.
and that appropriate services are provided for those tribunals (referred to in this section and in sections 40 and 41 as "the tribunals").
(2)Any reference in this section, or in section 40 or 41, to the Lord Chancellor's general duty in relation to the tribunals is to his duty under subsection (1).
(3)The Lord Chancellor must annually prepare and lay before each House of Parliament a report as to the way in which he has discharged his general duty in relation to the tribunals.


text:
Q: How can I use gettimeofday to measure the passage of time? I'm only allowed to use this function and I'm trying to figure out a way to calculate time elapsed, any ideas? I'm confused..
# include <sys/types.h>
# include <sys/time.h>
# include <stdio.h>
# include <unistd.h>

int main(int argc, char* argv[])
{
    struct timeval now;
    struct timeval start;
    int t_now;
    int t_stop;
    int t_start;
    int i;

    gettimeofday(&start, NULL);
    t_start = start.tv_usec / 1000;
    t_stop = t_start + 200;

    while (42)
    {
        usleep(2000);
        gettimeofday(&now, NULL);
        t_now = now.tv_usec / 1000;
        if (t_now - t_stop > -1)
        {
            break;
        }
        printf ("%d\n", t_now);
        usleep(2000);
    }
    return 0;
}

I was doing this but it will keep looping, and won't stop..

A: this
t_start = start.tv_usec / 1000;

isnt doing what you expect. tv_usec only has fractions of a second, you need
long long msec = (start.tv_sec * 1000) + start.tv_usec/1000;

to get total msec

redpajama_set_name: RedPajamaStackExchange


Enjoy a glamorous and conveniently situated wedding venue in downtown Hartford, Connecticut at the historic Goodwin! Between our beautiful venues, exceptional catering, and attentive event-coordinating staff, we serve as a top-caliber setting for a destination wedding in Connecticut's capital.
If you're curious about how we can make your Hartford wedding happen in glorious and unforgettable style, just drop us a line via our online RFP and we'll reach out to you in short order!
Our historic downtown hotel—an instantly recognizable feature of Hartford, with its grand terracotta façade—encompasses a range of function spaces ideal for wedding ceremonies and receptions. Biggest of all is our Capital Ballroom, nearly 1,200 square feet in area, which dazzles with its ring pendant chandeliers and sconces. Whether it's a small or a large ceremony, we'll work with you and your wedding coordinator to ensure our beautiful venues perfectly project your desired décor and theme.
From our wide array of chic guest rooms to our spacious suites and duplexes, we provide downtown Hartford's finest accommodationsfor you and your wedding party and guests. And our central location means we're exceedingly easy to reach and surrounded by some outstanding attractions for wining, dining, entertainment, and sightseeing during the wedding getaway's downtime.
So send us a wedding request, and we'll happily commence the process of composing a straight-out-of-a-dream ceremony for you, your betrothed, and your wedding guests here at our historic Hartford, CT hotel. Weddings and receptions rank high up there among the special events we truly love to host, and our experience and resources allow us to back up the sheer splendor of our venues to translate your matrimonial needs and wishes into an unforgettable reality.
We hope you'll consider The Goodwin for your downtown Hartford, CT wedding and reception!


text:
XB-IMG-176156
Xenbase Image ID: 176156
Figure 4. Clk2 promotes the development of both anterior and posterior neural tissues. Clk2 stimulated the expression of the anterior and posterior markers, otx2 (a–e) (■, Strongly; image, Weakly; □, Normal) and hoxb9 (f–h) (■, Strongly; image, Weakly; □, Normal), respectively. clk2 SYA‐GR (250 and 500 pg) and β‐galactosidase mRNAs were injected into one side of the animal hemisphere of X. laevis embryos at the 2‐cell stage. The injected side is marked by brackets. Expression of otx2 (b, d and d') and hoxb9 (g and g') is indicated by arrowheads and is classified as strongly or weakly expanded, or normal in e and h for otx2 and hoxb9, respectively. c', d', f' and g': magnification of c, d, f and g, respectively
Image published in: Virgirinia RP et al. (2019)
Copyright © 2019. Image reproduced with permission of the Publisher, John Wiley & Sons.


text:
Home News Regulus Axing 60% of Workforce, Pauses Patient Recruitment for Lead Program
Regulus Axing 60% of Workforce, Pauses Patient Recruitment for Lead Program
Regulus Therapeutics said it is eliminating 60% of its workforce as part of a restructuring designed to extend its available cash until mid-2019—the second time in 14 months that the company has cut jobs.
The 60% workforce cut would amount to 38 jobs, based on the 63-employee staff Regulus reported as of December 31, 2017. Of the 63 employees, 49 were engaged in R&D activities and 14 in finance, legal, human resources, facilities, and general management, Regulus stated in its Form 10-K Annual Report for 2017, filed March 8.
In May 2017, Regulus eliminated 30% of its workforce, approximately 30 jobs, in a restructuring that included the resignation of Paul Grint, M.D., as president and CEO, and his succession by Joseph P. "Jay" Hagan.
Yesterday Regulus also said it has "paused" recruitment activities for its lead clinical program, the Alport syndrome candidate RG-012 being developed through a collaboration with Sanofi Genzyme, while it pursues talks with partner Sanofi aimed at restructuring the partnership. That alliance stretches back to 2010, when Regulus received a $10 million equity investment from what was then called Sanofi-Aventis, in a collaboration valued at over $750 million and initially focused on fibrosis.
RG-012 is a single-stranded, chemically modified oligonucleotide designed to bind to and inhibit the function of microRNA 21 (miR-21) for the treatment of Alport syndrome, an inherited form of kidney disease caused by mutations in the type IV collagen genes (Col4A3, Col4A4, and Col4A5.
Regulus reported encouraging preliminary results from the first patients studied in a Phase I renal biopsy study (NCT03373786), saying that they showed modulation of miR-21 as well as kidney tissue concentrations that are predictive of therapeutic benefit based on animal disease models. Regulus is also recruiting patients for a Phase II study designed to assess safety and efficacy of RG-012 in approximately 40 males ages 18 to 60 with Alport syndrome (NCT02855268).
In addition, Regus voluntarily paused its Phase I multiple ascending dose (MAD) study for its autosomal dominant polycystic kidney disease (ADPKD) candidate RGLS4326 following undisclosed "unexpected observations" in the 27-week mouse chronic toxicity study.
The MAD study is designed to characterize the safety, tolerability, pharmacokinetics, and pharmacodynamics of increasing doses of RGLS4326 administered subcutaneously in healthy volunteers. The MAD study was launched based on data from a single ascending dose (SAD) Phase I study that has completed dose escalation and continues in the planned follow-up phase. Results from the MAD study are designed to support a Phase II proof-of-concept (POC) trial assessing RGLS4326 in ADPKD, which was previously planned to start in mid-2019.
The restructuring is projected to save Regulus more than $20 million annually—double the $10.057 million in cash and cash equivalents the company reported as of March 31, according to its Form 10-Q quarterly report for Q1 2018.
"Very Disappointed"
"I am very disappointed that we need to take these drastic steps to preserve our capital, especially given the significant contributions by our dedicated employees to the progress made toward unlocking the potential of targeting microRNAs," Hagan said in a statement.
Hagan said the observations in the mouse chronic toxicity study contrasted with the favorable safety profile of RGLS4326 in previous non-Good Laboratory Pracice (GLP) and GLP toxicity studies at the same or similar doses supporting the company's Investigational New Drug (IND) and Phase I program for the candidate.
RGLS4326 is a novel oligonucleotide designed to inhibit microRNA 17 (miR-17) by targeting the kidney. Preclinical studies with RGLS4326 have demonstrated a reduction in kidney cyst formation, improved kidney weight/body weight ratio, decreased cyst cell proliferation, and preserved kidney function in mouse models of ADPKD.
In the near term, Hagan said, Regulus will focus on investigating the unexpected mouse toxicity findings in the RGLS4326 study, shifting its preclinical research effort toward its hepatitis B virus (HBV) programs, and "looking for additional ways to improve shareholder value."
In consultation with the FDA, Regulus said, it is pursuing the toxicity investigation and planning a new 27-week mouse chronic toxicity study with unspecified changes expected to address the unexpected findings. The company said the changes will not affect a separate 40-week nonhuman primate chronic toxicity study, which continues with no significant findings to date.
Regulus said will overhaul its preclinical R&D by focusing on HBV while seeking partners for its other programs, which include glioblastoma multiforme (targeting microRNA 10b) and three indications with undisclosed targets—nonalcoholic steatohepatitis (NASH), infectious diseases, and immunology.
"The Company has determined that advancing its preclinical programs targeting HBV represents the most attractive opportunity in its pipeline for investment, affecting an estimated 350 million people worldwide.," Regulus stated.
The HBV treatments will target multiple undisclosed microRNAs that serve as host factors for the virus. The treatments be designed to attack those host factors with GalNAc-conjugated oligonucleotides directed to the liver—an approach the company used in its preclinical hepatitis C virus program, which has shown human POC by targeting microRNA 122 (miR-122).
Regulus added that it now expects to file an IND for the HBV program in the second half of 2019, "with the potential of achieving human POC in a Phase I study."
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"Sciences are the 'how'. Humanities are the 'why'. I don't think you can have the 'how' without the 'why'," said George Lucas, Producer, Screen-writer and Director in the film Heart of the Matter made for the American Academy of Arts and Sciences.
This high-level international conference at the British Academy, organised in partnership with the American Academy of Arts and Sciences, brings together distinguished leaders across the humanities, sciences and social sciences, from the USA and the UK to promote the essential nature of these areas of endeavour together.
During the conference, speakers and participants examine how a co-ordinated approach across these disciplines might serve to prepare tomorrow's leaders, as well as drive prosperity through economic, cultural, social and scientific endeavour.


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[CCP Interview]: Great Good Fine OK on the Group's Genesis Story & their Stylistic Influences
Posted on July 16, 2015 July 19, 2015 by poetryinanemptycokecan
It's been a busy past year for Great Good Fine OK, who since their relatively recent inception have put out two EP's — Body Diamond and 2M2H under major label Sony. The Brooklyn duo is comprised of vocalist Jon Sandler and musician Luke Moellman, who have a flair for falsetto and shiny '80s-imbibed production, respectively. We caught up with the guys of GGFO before their explosive set at DC9 to discuss the genesis of their name, their live musical influences, Justin Bieber, collaborating with artists such as St. Lucia, and the 'fanciest' deli in Brooklyn.
Thanks for taking the time to chat with CCP! First things first, how did GGFO come together?
Jon: Luke was living around the corner from me in Brooklyn with a friend of mine and a former bandmate, so we had become friends. Then one day about two years ago we said 'let's collaborate on something' and decided to write a song together. Luke sent me the music to our first track ("You're The One For Me") and I wrote the lyrics and melody that night. We were both pumped about it, sent it to some friends who were also pumped about it and that's kinda how it started. We formed a team around that one song, continued writing more songs until eventually we put a band together.
Luke: Yeah I remember we were walking back home from where we recorded the vocals and were like, 'This is cool, we should start a real band.' And Jon relayed he'd been saving the perfect band name his whole life. He was like, 'It's so good you ready to hear it?' And I was bracing myself for it to not be that good. He said "Great Good Fine OK" and I was like okay.
Jon: We marinated on it for two months and asked everyone we knew what we thought – I feel like it was a 50/50 split of people that loved it or hated it. So we were on the fence but we had been talking about it and calling the project that for so long that when it came time to actually start making a Facebook page and such we were just like, that's it.
We dig it [so much so that we bought a t-shirt!]. Has the creative / songwriting process stayed the same since that initial song?
Luke: More or less. Sometimes it's a really developed and thought out structure, other times it's a couple of ideas strung together. I'll send it to Jon, he'll add some stuff and we'll go back and forth.
Did either of you study music growing up?
Luke: I did, I went to music school at University of Miami.
Jon: I did not, but I've just been singing my whole life. I was in choir since as long as I can remember, performed in musicals in high school and was in a couple of bands in college.
Speaking of performing, you guys have talked about how you were inspired by iconic '80s pop stars like Prince and Michael Jackson. In what ways have those artists influenced you?
Luke: It's a combination of things – the musical style, the charisma of the performers, the catchy melodies, the rhythmic delivery of Michael Jackson, the falsetto stuff that Prince does, and the production of Quincy Jones.
Jon: Yeah, the songwriting but also the performance element of those artists informs what I want the live show to be like.
And who are you listening to currently?
Luke: Russian artist Tesla Boy, our friends Joywave who just came out with their debut album, Alina Baraz, and Shura.
Jon: I'm also personally obsessed with Jack Ü – especially that Justin Bieber song ["Where Are Ü Now"]. I think I listened to that about 100 times this past week, I don't know why it's speaking to me. I've been writing a lot for EDM artists so my brain has been tapped into that world and I've been exploring and appreciating really good EDM tracks, so that's where I stumbled upon Jack Ü. I also co-wrote and performed on a Chainsmokers song and they're awesome — travelling all over the world and killing it right now. We love them.
We love The Chainsmokers collab ("Let You Go"). You guys also worked with with St. Lucia recently. How did those collaborations come about?
Luke: Yeah the guys from The Chainsmokers had reached out to us. For the St. Lucia track, we had this song ("Something To Believe In") with Jon singing those parts that St. Lucia sings (the lower stuff), and as we were sitting around one day trying to finish up the EP we realized it sounded like Jon was trying to sing like Jean-Philip from St. Lucia. We had just run into him at a Christmas party and thought it'd be cool to try to get him, so we wrote him an email and he was so nice — he was right in the middle of working on their new album so we were like we'll understand if you won't be able to do it. He happened to be on vacation with his wife in Germany, but he had a mic with him so he did it in his spare time and sent it back to us. It was perfect.
What inspired the title track of the EP, "Too Much To Handle"?
Luke: That song started with the music I sent to Jon; I had just moved out of an apartment that I had been living in with an ex-girlfriend I'd just broken up with. So I was living in a new place and whatever energy was going on at that time just kinda came out through that song.
Jon: Weirdly, whatever Luke sends me, even if he doesn't tell me what it's about I seem to write something that goes along with it. To me that song is just about how tough life can be and how you always seem to get through it.
What's next for Great Good Fine OK?
Jon: We're writing and recording a lot, accumulating songs, trying to figure out how we want to release more stuff, and then touring in the fall. We just got off the tour with Magic Man and we're chomping at the bit to get back at it.
Naturally. What's your favorite spot to grab a bite or beverage in Brooklyn?
Jon: There's this deli / bodega around the corner from me that I call "Fancy deli" that I get sandwiches from four or five times a week.
Luke: There's a cool speakeasy bar on Vanderbilt. No signage of course.
Listen to Great Good Fine Ok's single with The Chainsmokers "Let You Go" below and be sure to like them on Facebook to keep up with their latest happenings. Their live show (and Jon's dance moves) are not to be missed.
As a bonus, check out this fantastic, synth-laden remix by house producer Vasta and grab a free download on his Soundcloud page.
Posted in audioTagged Great Good Fine Ok, indie-pop, remix, Sony Music, The Chainsmokers, VastaLeave a comment
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Hrithik Roshan is all geared up for the biopic revolving around the life of Anand Kumar. The actor, who is all set to play a teacher in his next titled Super 30, gave a sweet surprise to his young co- actors. The actor gave away merchandise of his fitness brand HRX. HRX is founded and owned by Hrithik Roshan. After the team of Super 30 shot the climax in Mumbai, Hrithik who had planned the surprise in advance gave the gifts to his 30 co- actors who portray his 30 students in the film.
Spanning across cities, the makers of Super 30 shot for their first schedule extensively in real location in Benaras and, have recently wrapped up for the 2nd schedule of the movie in Mumbai. The actor has been donning the look perfectly with a beard and unkempt hair keeping the character details intact.
Based on Anand Kumar's educational program Super 30, the film will showcase Hrithik Roshan in a never seen before avatar. The actor will be seen portraying a North Indian (Bihari) role for the first time and the fans are more than excited to witness the unusual character of Hrithik.
For the uninitiated, Super 30 is based on the academic initiative started by mathematician Anand Kumar that made him popular. The Patna based scholar every year selects 30 smart but underprivileged students to help them crack the JEE tests for IIT [Indian Institute of Technology]. From study materials to meals, the children are taken care of by Anand and his team.
Helmed by Vikas Bahl, co-produced by Reliance Entertainment and Sajid Nadiadwala's NGE Productions, Super 30 starring Hrithik Roshan is slated to release on 25th January 2019.


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The National Housing Trust Fund (NHTF) is a dedicated federal fund that will provide resources that will preserve, build, and rehabilitate housing for extremely low income Virginians (30 percent Area Median Income or lower). All NHTF funding will be made available through DHCD's Affordable and Special Needs Housing application review process.


Star Red Sox outfielder Mookie Betts has been named American League MVP.
Major League Baseball announced Thursday that Betts had been voted Most Valuable Player for the 2018 season. He received 28 first-place votes out of a possible 30.
Los Angeles Angels center fielder Mike Trout finished second in the balloting with one first-place vote. Cleveland Indians infielder Jose Ramirez came in third.
One first-place vote went to Betts' teammate, Red Sox designated hitter J.D. Martinez, who finished fourth.
Betts, who turned 26 in October, has proven to be a force since ascending to the big leagues in June of 2014, but 2018 has been, far and away, his best season to date. He posted career highs in homers (32), steals (30), batting average (.346), on-base percentage (.438), slugging average (.640) and on-base plus slugging (1.078). And he did so while providing outstanding defense in right field.
For the sabermetric-minded, Betts was the most productive player in the MLB this year, with 10.9 wins above replacement as calculated by Baseball-Reference and 10.4 WAR as calculated by Fangraphs.
The award caps off a memorable season for Betts, who helped the Red Sox win a franchise-record 108 games in the regular season on their way to a World Series championship.
"It means a lot," Betts said on MLB Network while cradling his newborn daughter, who stayed asleep as his friends and family members cheered. "It's definitely a special award, and something that I'll cherish, but I think the most important thing is, that you know, we won a World Series and got to bring a trophy back to Boston."
Betts has received MVP votes in all four of his full seasons, serving as runner-up to Trout in 2016. He has been an All-Star in each of the last three seasons.
Milwaukee Brewers outfielder Christian Yellich took home the NL MVP Award in his first season with the club following a trade from the Miami Marlins.


Oregon Recreational Marijuana Laws | Medical Marijuana Inc.
Beginning October 1, Oregon's recreational marijuana users will be able to make their purchases at their local medical marijuana dispensary. The Oregon Health Authority has so far been notified of plans to sell recreational marijuana by more than 200 of the 345 marijuana dispensaries throughout the state.
Recreational marijuana became legal in the state after the passing of Measure 91 last November, allowing adults to possess and grow limited amounts of marijuana for personal use, but the state hadn't licensed any stores and won't be ready to regulate sales until next year. Giving the dispensaries the green light for recreational sales is an attempt to prevent black market sales. Dispensaries will be able to sell marijuana tax-free until January 4, after which recreational retail sales will fall under the Oregon Liquor Control Commission's regulations, be sold at OLCC-licensed retail stores and feature a 25 percent tax.
The state projects an additional $10.7 million in revenue from recreational marijuana sales for the 2015-2017 biennium, according to the Oregon Liquor Control Commission. Forty percent of the tax revenue will go to Common School Fund.
Provided they present a valid, government-issued photo ID, adults over 21 will be allowed to purchase a quarter ounce of buds per day. Marijuana edibles will not be available for early recreational sales.
Not all of Oregon is allowing dispensaries to sell recreationally. Ten cities and two counties have prohibited early recreational marijuana retail sales.
Most of Oregon's dispensaries, however, are excited for what they expect to be a large boost in sales. "It's going to be a surprise for everybody, we're hoping it's really busy," Lois Parisea of Portland dispensary Gras Cannabis told the Seattle Times.
One concern about the new, likely mighty, influx of marijuana sales is the potential lack of supply for medical patients.
"We're really nervous. The dispensaries might sell all the marijuana to recreational people and the patients will be left without their medicine," Anthony Taylor, president of the nonprofit group Compassionate Oregon, told the Seattle Times.
Taylor also expressed concern about the impact on price with the increase of demand. He has sent letters to dispensaries encouraging them to set aside enough supply to adequately provide the medical patients.


The other day a client's parent asked if I prescribed medication because she saw that my title notes "Licensed Clinical Psychologist". I explained that only psychiatrists, who are medical doctors, and other doctors such as nurse practitioners, general practitioners, neurologists, and pediatricians can prescribe medication to individuals.
She was relieved because prescribing medication for mental health issues was at the bottom of the list for her child. It got me thinking though, how many other parents may be swayed to think that because my title has the word "clinical" I am pro medication prescription or that I can prescribe medication.
Psychiatrists are medical doctors who have a specialty in treating mental health disorders. They attend general medical school and then apply for a 3-4 year residency in psychiatry. In the past, psychiatrists offered psychotherapy, but now, most mainly prescribe medication after an initial consultation and then follow the client for medication management.
Psychologists include therapists with PsyD and PhD degrees in clinical and counseling psychology. They attended approximately 5-6 years of graduate school, 1-2 years of internship, and 1-2 years of supervised clinical work experience before even earning their license. Their work is in psychotherapy, backed up by psychological theory, research, and practice. Psychologists are the only group of therapists trained in psychological testing. This requires years of training in administration, interpretation, and integration of tests and test results. The term "psychologist" can only be used by someone with a state and national license and with the above training.
Therapist can include licensed mental health counselors (LMHC), clinical social workers (LCSW), and other mental health therapists who have earned a Master's degree in their field. This includes 2 years of graduate education and 1-2 years of supervised work experience. They also work with individuals to help them overcome mental health issues.
Here in Miami, many experienced and seasoned therapists hold Master's degrees from local universities and doctorate or psychologist degrees from their home country. It is often cumbersome and costly for psychologists immigrating to the United States to re-attend graduate school given the amount of years necessary to earn that degree and especially if they already have that breadth of knowledge and experience.
Regardless of the therapist's title, what is most important is the connection made between the client and the clinician. As therapists, we may have differing backgrounds but our main goal is to help the client improve their day to day living and enjoy life to its fullest.


Congrats to the Joe and Cyn.
He says the coaches are "trying to baby" his son, Lonzo Ball.
It happened on Sunday morning.
He could be banned from Lakers if more evidence is found.
The former NBA player gets candid.


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