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Personal physician to the Dalai Lama speaks on compassion in medicine at UofL White Coat Ceremony
Barry Kerzin, M.D., addresses School of Medicine class of 2020
Barry Kerzin, M.D.
Barry Kerzin, M.D., personal physician to the Dalai Lama and founder of the Altruism in Medicine Institute, addressed the 156 members of the incoming class of the University of Louisville School of Medicine and guests at the school's White Coat Ceremony on Sunday, July 24. Kerzin, an American trained physician and Buddhist monk, spoke to the students about cultivating and preserving the desire to help others.
"Compassion is the chief reason we all go into medicine," Kerzin said prior to the event. "Research suggests at the third year of medical school, compassion in medical students decreases significantly. I'll address how to sustain our compassion through our training and out in the world practicing medicine."
The ceremony welcomeed the class of 2020 to the UofL School of Medicine. The students each received a white coat, a gift from the Greater Louisville Medical Society, and a stethoscope, provided by an alumnus of the school through Stethoscopes for Students. The white coat symbolizes cleanliness, as well as the sense of compassion that inspires students to become physicians. At the ceremony, the students recited the Declaration of Geneva, promising to serve humanity and honor the traditions of the medical profession.
Kerzin, a California native, is a board-certified family medicine physician and an honorary professor at the University of Hong Kong School of Medicine. He is a former assistant professor of medicine at the University of Washington School of Medicine in Seattle. After traveling to India in the 1980s to help train Tibetan doctors in modern research methods, he studied Buddhism and meditation and ultimately was ordained as a Buddhist monk. Kerzin now provides medical care to the poor in India and serves as a personal physician to the Dalai Lama in addition to traveling around the world to teach about meditation and compassion. He founded the Altruism in Medicine Institute with the goal to bring more compassion into health care.
UofL School of Medicine White Coat Ceremony
Sunday, July 24, 3-5 p.m.
Louisville Downtown Marriott
280 W. Jefferson St., Louisville, Ky., 40202
Originally published July 20, 2016. Updated August 5, 2016.
A life in the clouds: The science of extreme weather
UofL weather researcher will discuss cloud physics and climate change at Beer with a Scientist, Jan. 23
A rotating thunderstorm, called a supercell, in northwestern Minnesota. Photo by Naylor
With spring just around the corner, Louisville area residents will expect not only April showers and May flowers, but spring tornadoes. These destructive storms are fairly common in the greater Louisville area, which may lead weather buffs to wonder: What causes tornadoes and what makes them more or less destructive?
At the next Beer with a Scientist, Jason Naylor, Ph.D., an assistant professor at the University of Louisville, will discuss the formation of tornadoes and share data that indicate there may be pockets in and around Louisville that are more prone to severe weather. Naylor studies severe weather events with the goal of identifying factors that affect their intensity, duration and frequency.
"The number of tornadoes in the United States in 2018 was far below normal. This may have been an anomaly or it may be related to climate change," Naylor said. "There are factors related to climate change that may impact the frequency and spatial distribution of U.S. tornadoes and other severe weather events."
He also will discuss how humans may be affecting severe weather on a smaller, more local scale. His current research is investigating how severe weather patterns may be altered by the presence of large cities.
Naylor's talk will begin at 7 p.m. on Wednesday, Jan. 23, at Holsopple Brewing, 8023 Catherine Lane, Louisville, 40222. A 30-minute presentation will be followed by an informal Q&A session.
Admission is free. Purchase of beer or other items is not required but is encouraged.
Organizers encourage Beer with a Scientist patrons to drink responsibly.
UofL cancer researcher Levi Beverly, Ph.D., created the Beer with a Scientist program in 2014 as a way to bring science to the public in an informal setting. At these events, the public is invited to enjoy exactly what the title promises: beer and science.
Upcoming Beer with a Scientist dates: Feb. 13, March 13, April 17, May 15.
International Americans help make up Louisville MOSAIC
Three from UofL among five receiving annual awards
2017 MOSAIC Award recipients, left to right: Anna Faul, John La Barbera, Vik Chadha, Barry Barker and CoCo Tran.
Two University of Louisville faculty members and an entrepreneur affiliated with the university's co-working space iHub are among the five honorees of the 2017 MOSAIC Awards, scheduled for presentation May 18 at the Hyatt Regency Louisville.
Named to recognize "Multicultural Opportunities for Success and Achievement In our Community," the MOSAIC Awards benefit Jewish Family & Career Services and honors international Americans who make a significant contribution in their profession and in the local and global communities.
From UofL, faculty members Anna Faul, Ph.D., and John La Barbera and iHub co-founder Vik Chadha will be honored, along with J. Barry Barker, director of Transit Authority of River City (TARC), and restaurateur Huong "CoCo" Tran.
"JFCS was founded to assist newcomers to Louisville, and this event honors its original mission," Judy Freundlich Tiell, JFCS executive director, said. "To date, the event has recognized 57 international Americans who make our community a richer and more interesting city, creating a mosaic of many colors and perspectives."
At the event, a cocktail reception will start at 5:30 p.m., featuring a showcase of new micro-businesses that have received training and financial assistance from the JFCS Navigate Enterprise Center. Dinner and the awards presentation will follow.
Tickets to the event are $150 per person, and table sponsorships begin at $2,000. For reservations, contact Beverly Bromley, JFCS director of development, at 502-452-6341, ext. 223 or bbromley@jfcslouisville.org.
Title sponsor of the MOSAIC Awards is the Jewish Heritage Fund for Excellence. Kindred Healthcare is the new American sponsor. WLKY32 is the media sponsor and Papercone Corp., PharMerica, TARC and Churchill Downs are major sponsors. Rachel Greenberg is this year's event chair.
About the 2017 MOSAIC Award winners
Annatjie Faul, Ph.D. – South Africa
Faul originally hails from South Africa and is Executive Director of the Institute for Sustainable Health and Optimal Aging at the UofL Health Sciences Center and Associate Dean for Academic Affairs at the Kent School of Social Work. A specialist in gerontology, Faul has been awarded multiple grants to develop rural health collaborations that address serious diabetes problems in the outlying rural areas of the state. She has established outreach programs to Latinos and Hispanics, created services in rural Kentucky, and most recently was awarded more than $2 million to help primary physicians in the region better serve the geriatric populations.
John La Barbera – Sicilian Descendant
The son of Sicilian immigrants, La Barbera is a first-generation American and Grammy-nominated composer/arranger whose music spans many styles and genres. He is a professor emeritus of music at the UofL School of Music and is an international music clinician and lecturer whose topics range from composing and arranging to intellectual property and copyright. His works have been recorded and performed by Buddy Rich, Woody Herman, Count Basie, Dizzy Gillespie, Mel Torme, Chaka Kahn, Harry James, Bill Watrous and Phil Woods, to name a few. Though his major output has been in jazz, he has had works performed and recorded for symphony orchestra, string chamber orchestra, brass quintet and other diverse ensembles. He is a two-time recipient of The National Endowment for the Arts award for jazz composition. His published works are considered standards in the field of jazz education.
Vik Chadha – India
A native of India, Chadha is the co-founder of two successful technology companies - Backupify and GlowTouch - that collectively employ more than 1,300 people globally. He was instrumental in conceptualizing and creating the high-tech, co-working space, iHub, at UofL's J.D. Nichols Campus for Innovation and Entrepreneurship. His roles at EnterpriseCORP, the entrepreneurial arm of Greater Louisville Inc., and Nucleus allowed him to help create hundreds of high-paying jobs within the city of Louisville, and he has played an instrumental role in developing the city's entrepreneurial environment. Chadha is a board member of the Jefferson County Public Education Foundation and was recently appointed by the governor to the board of the Kentucky Work Ready Skills Initiative.
J. Barry Barker – Great Britain
Barker is from England and has been a leader and innovator in the fields of public transit and community planning for over four decades. Currently he manages a $64 million budget serving as the director of TARC. His primary contributions in the field include introduction of service innovations, priority on and increasing customer centric services, initiating improvement in labor-management relations, and improved safety and environmental leadership. Also, he has added hybrid and electric buses and significantly increased outside funding for Louisville's transit authority. He has served as a board member and chaired many community boards and has been recognized and awarded for his contributions by many local and national organizations.
Huong "CoCo" Tran – Vietnam
A Vietnamese refugee in 1975, Tran opened the first Chinese fast food restaurant in Louisville. Since opening the Egg Roll Machine, she has opened a total of nine restaurants. She hired many of the first Vietnam refugees who came to Louisville. She has impacted the community greatly by promoting healthy eating. She encourages and guides other Asian entrepreneurs by mentoring them. For the past 16 years, each of her vegetarian restaurants has provided free meals on Thanksgiving Eve. She is a member and a strong supporter of the Vietnamese Community of Louisville and served on the Advisory Community Board.
Epidural stimulation leads to improved regulation of blood pressure in spinal-cord-injured people
Research from UofL published in JAMA Neurology shows recovery of cardiovascular function in spinal-cord-injured people sustained following epidural stimulation training
Stefanie Putnam and Glenn A. Hirsch, M.D.
For the first time since 2009, Stefanie Putnam is able to prepare – and eat – meals for herself, put the vest on her service dog, Kaz, and drive herself to activities with her horse without losing consciousness or gasping for breath.
"My whole life has opened up for me again!" Putnam said.
A C4 spinal cord injury in 2009 left Putnam paralyzed from the neck down and suffering from chronic low blood pressure. She relied on medication and tight corsets to maintain her blood pressure, but she still passed out five or six times a day.
Her new lease on life is the result of spinal cord epidural stimulation (scES) she received as a participant in research at the University of Louisville's Kentucky Spinal Cord injury Research Center (KSCIRC) to aid recovery for individuals with spinal cord injury. Research published today in JAMA Neurology describes the improvements Putnam and three other research participants experienced in blood pressure and heart rate regulation during and after scES. All four participants had chronic, complete cervical spinal cord injury, persistent low resting blood pressure and blood pressure decrease when sitting up prior to receiving scES.
[Video story on Youtube]
"From a quality of life perspective, orthostatic hypotension, or low blood pressure when sitting up, is truly life limiting," said Glenn A. Hirsch, M.D., a cardiologist with the UofL School of Medicine and co-author of the study.
Spinal cord epidural stimulation uses an implanted electrode array to deliver electrical signals to the lumbar spine. For this study, research participants received stimulation using specific configurations selected to target cardiovascular function, monitoring blood pressure and cardiovascular function throughout, for an average of 89 daily, two-hour sessions. Earlier research showed the benefits of scES in controlling cardiovascular function during stimulation, but this data reveals participants' blood pressure and heart rate remained stabilized between sessions, showing an enduring effect.
"What was most surprising was that only having it on for a few hours a day, we were noticing participants having normal blood pressure through longer periods of each day," Hirsch said. "We are noticing it now across the research participants who had that problem, that there is a prolonged stabilizing effect even after the stimulator is turned off."
Since receiving scES for her cardiovascular symptoms, Putnam said she enjoys increased independence and alertness, and she no longer needs medication to increase her blood pressure.
"I am an active member in my own life instead of merely existing. I am really living! I can prepare and cook my own meals. I can feed myself and carry on a conversation. Without the disruption of passing out or gasping for breaths in the middle of a task or having to stop and be back in my chair for two hours at a time, I can accomplish so much more. Now I can live my best life with energy to focus on my future." Putnam said.
Research at UofL using scES, led by Susan Harkema, Ph.D., associate director of KSCIRC and professor of neurosurgery at UofL, began with the goal of restoring motor function. However, researchers and participants soon noticed stimulation led to improvements in cardiovascular and autonomic systems as well.
"In our motor system studies, we observed that we could actually regulate blood pressure without activating the motor system. That launched us into another area of research," Harkema said. "Many people don't realize that walking in many cases is not really the aspect that makes their daily lives most difficult because they have cardiovascular dysfunction and problems with respiratory, bowel, bladder, and sexual function. All of those things are disrupted so every day is incredibly difficult for people with spinal cord injury."
In ongoing research to explore further the life-enhancing effects of epidural stimulation, the UofL researchers are conducting a six-year study with 36 participants with chronic, complete spinal cord injuries.
To learn more about supporting and participating in spinal cord injury research at UofL, visit the university's Victory Over Paralysis website: victoryoverparalysis.org.
Today's published research, "Epidural Spinal Cord Stimulation Training and Sustained Recovery of Cardiovascular Function in Individuals with Chronic Cervical Spinal Cord Injury," was supported by the Craig H. Neilsen Foundation, The Leona M. and Harry B. Helmsley Charitable Trust, University of Louisville Hospital, Christopher & Dana Reeve Foundation and Medtronic Plc.
UofL Hospital earns Get With The Guidelines-Stroke Gold Plus Quality Achievement Award
American Heart Association recognizes commitment to quality stroke care
University of Louisville Hospital has earned the Get with the Guidelines® Stroke Gold Plus Award continuously for the past 12 years.
University of Louisville Hospital, a part of KentuckyOne Health, has earned the American Heart Association/American Stroke Association's Get With The Guidelines®-Stroke Gold Plus Quality Achievement Award with Target: Stroke Honor Roll Elite Plus. The award recognizes the hospital's commitment to providing the most appropriate stroke treatment according to nationally recognized, research-based guidelines based on the latest scientific evidence.
Hospitals must achieve 85 percent or higher adherence to all Get With The Guidelines-Stroke achievement indicators for two or more consecutive 12-month periods and achieve 75 percent or higher compliance with five of eight Get With The Guidelines-Stroke Quality measures to receive the Gold Plus Quality Achievement Award.
To qualify for the Target: Stroke Honor Roll Elite or Elite Plus, hospitals must meet quality measures developed to reduce the time between the patient's arrival at the hospital and treatment with the clot-buster tissue plasminogen activator, or tPA, the only drug approved by the Food and Drug Administration to treat ischemic stroke. If given intravenously in the first three hours after the start of stroke symptoms, tPA has been shown to significantly reduce the effects of stroke and lessen the chance of permanent disability.
These quality measures are designed to help hospital teams follow the most up-to-date, evidence-based guidelines with the goal of speeding recovery and reducing death and disability for stroke patients.
"University of Louisville Hospital has been recognized with the Stroke Elite Plus award again as we continue to strive for excellence in the acute treatment of stroke patients," said Kerri Remmel, M.D., Ph.D., chair of UofL's Department of Neurology and director of the UofL Hospital Stroke Center. "This recognition further reinforces the UofL stroke team's hard work and commitment to caring for patients with stroke."
UofL Hospital now has received the Get with the Guidelines® Stroke Gold Plus Award for the past 12 years. In 2004, UofL Hospital became Kentucky's first Joint Commission-certified Primary Stroke Center and in 2012, the hospital became Kentucky's first Joint Commission-certified Comprehensive Stroke Center, the 20th in the nation.
"Stroke is 80 percent preventable. High blood pressure, diabetes, cigarette smoking, high cholesterol, atrial fibrillation and sedentary lifestyle are treatable and modifiable risk factors. If we could give the community one message for the prevention of stroke, it would be to know your own risk factors and be aggressive about controlling them," Remmel said.
According to the American Heart Association/American Stroke Association, stroke is the No. 5 cause of death and a leading cause of adult disability in the United States. On average, someone in the U.S. suffers a stroke every 40 seconds, someone dies of a stroke every four minutes, and nearly 800,000 people suffer a new or recurrent stroke each year.
About Get With The Guidelines®
Get With The Guidelines® is the American Heart Association/American Stroke Association's hospital-based quality improvement program that provides hospitals with tools and resources to increase adherence to the latest research-based guidelines in stroke, heart failure, resuscitation and atrial fibrillation. Developed with the goal of saving lives and hastening recovery, Get With The Guidelines has touched the lives of more than 6 million patients since 2001.
Get With The Guidelines®-Stroke puts the expertise of the American Heart Association and American Stroke Association to work for hospitals nationwide, helping hospital care teams ensure the care provided to patients experiencing stroke is aligned with the latest research-based guidelines. Developed with the goal to save lives and improve recovery time, Get With The Guidelines®-Stroke has had an impact on more than three million patients since 2003. For more information, visit heart.org.
Can increasing green space improve our health?
Learn about research into the effects of foliage on health at Beer with a Scientist Mar. 14
In neighborhoods with poor air quality and many busy streets, residents have a higher risk of heart disease. Researchers at the University of Louisville are studying air quality, innovative landscape design and human health to determine, scientifically, whether planting more trees and adding greenspaces in a neighborhood could increase the health of its residents.
Aruni Bhatnagar, Ph.D., director of the Diabetes and Obesity Center at UofL, will discuss the research, the Green Heart Project, at the next Beer with a Scientist event.
"No one knows whether and to what extent trees and neighborhood greenery affect human health and why," Bhatnagar said. "This work will tell us how to design a neighborhood that supports human health and whether an increase in the urban greenspaces and vegetation could enhance physical and mental health by decreasing the levels of ambient air pollution."
The Green Heart Project is a collaboration of UofL, The Nature Conservancy, Hyphae Design Laboratory, the Institute for Healthy Air Water and Soil, the U.S. Forest Service and the City of Louisville. The goal of the project is to assess how residential greenness and neighborhood greenspaces affect the health of our communities by decreasing the levels of pollution and promoting physical activity and social cohesion.
The talk begins at 8 p.m. onWednesday, Mar. 14, at Against the Grain Brewery, 401 E. Main St. in Louisville. A 30-minute presentation will be followed by an informal Q&A session.
Admission is free. Purchase of beer, other beverages or menu items is not required but is encouraged.
Organizers add that they also encourage Beer with a Scientist patrons to drink responsibly.
UofL cancer researcher Levi Beverly, Ph.D., created the Beer with a Scientist program in 2014 as a way to bring science to the public in an informal setting. Once a month, the public is invited to enjoy exactly what the title promises: beer and science. For more information and to suggest future Beer with a Scientist topics, follow Louisville Underground Science on Facebook.
At the next Beer with a Scientist, Apr. 18, Deborah Yoder-Himes, Ph.D., will discuss super bacteria, antibiotic resistance and why everything is labeled "anti-bacterial."
Whale of a tale: How marine mammal research informs us about global pollution at Beer with a Scientist, June 15
John Pierce Wise Sr., Ph.D.
Obtaining and studying tissue samples from hundreds of whales around the world has been a mission and a passion for John Pierce Wise Sr., Ph.D. for the past 18 years.
A professor in the Department of Pharmacology and Toxicology at the University of Louisville, Wise is a leading authority on metal-induced cancer development. He studies the mechanisms of cancer and investigates the health impacts of chemicals and toxic metals in the environment, comparing their effects in humans with whales, sea turtles, alligators and other wildlife. Wise has conducted more than two dozen marine research expeditions, including three in the Gulf of Mexico following the explosion of the Deepwater Horizon oil well. In April, his team collected tissue samples from free-ranging whales in the Sea of Cortez. Read more about this trip, including a video of his first encounter with a majestic blue whale, at http://uoflnews.com/section/science-and-tech/encounter-of-a-lifetime-uofl-researcher-finally-meets-a-blue-whale/.
At this month's Beer with a Scientist, Wise will share his experiences on the water and explain how his research, funded by the U.S. Army, NIH, NASA, NOAA and other sources, is improving our understanding of the effects of environmental pollutants in marine life and in humans.
The program begins at 8 p.m. on Wednesday, June 15 at Against the Grain Brewery, 401 E. Main St. A 30-minute presentation will be followed by an informal Q&A session.
The Beer with a Scientist program began in 2014 and is the brainchild of UofL cancer researcher Levi Beverly, Ph.D. Once a month, the public is invited to enjoy exactly what the title promises: beer and science.
For more information and to suggest future Beer with a Scientist topics, follow Louisville Underground Science on Facebook.
Rising country duo Brothers Osborne added to Julep Ball lineup
'Hart of Dixie,' 'Anger Management' star Laura Bell Bundy also scheduled to perform
Two of the hottest acts making names for themselves in country music have just been added to the lineup of performers at The Julep Ball.
The duo Brothers Osborne, who recently dropped their latest single "Rum,"and Hart of Dixie and Anger Management star Laura Bell Bundy, whose country single "Giddy On Up" garnered over 4 million streams, will join J.D. Shelburne and the Bob Hardwick Sound on The Julep Ball stage.
The premier Derby Eve Party with a Purpose, The Julep Ball is held annually on the evening before the Kentucky Derby and supports the work of the James Graham Brown Cancer Center at the University of Louisville. The event on May 2 at the KFC Yum! Center kicks off with a 6:30 p.m. cocktail reception, followed by dinner and a live auction at 8 p.m.
An Official Event of the 140th Kentucky Derby®, The Julep Ball provides a celebrity-studded night to remember with a multi-course seated dinner, a knock-your-socks-off auction, multiple open specialty bars, complimentary valet parking, and dancing until the wee hours of Derby morning. A limited number of tickets to The Julep Ball are still available. The full evening's entertainment is $600 per person, $5,000 for a table of 10, and $100 per person for dance-only tickets. For further information and to buy tickets, go to The Julep Ball website, julepball.org.
About Brothers Osborne:
One of 15 acts chosen by Country Weeklyas "Ones to Watch in 2014," Brothers Osborne were chosen this month to open for Eric Church in his upcoming tour that includes a stop in Louisville at the KFC Yum! Center on Sept. 25.
The current Rolling Stone(April 24) hails the duo's current single "Rum": "There are plenty of drinking songs coming out of Nashville these days, but this twangy party anthem by a rising sibling duo from Maryland takes the genre to a whole new level of catchy fun. Sounds like a hit to us!"
For John and TJ Osborne, getting into music was unavoidable. Growing up in the water town of Deale, Md., their close-knit-family of seven spent most nights not in front of the television, but writing and playing songs.
John (guitar) moved to Nashville first to play in other bands before TJ (vocals/guitar) joined him. It was then they formed Brothers Osborne and began playing as many writer rounds as they could. In April 2011, Warner Chappell/King Pen Music offered them a publishing deal. A year later, Capitol Records offered them a record deal. The Brothers Osborne are currently in the studio finishing their debut album, an album they describe as "aggressive, bold and fragile at times." For more information, visit www.brothersosborne.com.
About Laura Bell Bundy:
A Kentucky native, Laura Bell Bundy is a performer who has done it all: from appearing on the Broadway stage as Elle Woods in Legally Blonde – a role that garnered her a Tony Award nomination – Glinda in Wicked, and Amber Von Tussle in the original cast of Hairspray, to the launch of her country music career with a captivating performance on the nationally televised Academy of Country Music Awards, to acting in various film and TV roles including Dreamgirls, Jumanji, The Adventures of Huck Finn, MTV's smash telecast of Legally Blonde, Guiding Light, CBS's How I Met Your Mother, Malibu Country, Home Improvement and Cold Case. Bundy's screen success has followed her to the web, where she has attracted a worldwide audience with her hit comedic web series, Cooter County, which she created, produced and directed.
Bundy released her debut country music album, Achin' and Shakin', in 2010, featuring her hit single "Giddy On Up," which has since garnered over 4 million streams and has been certified gold in Norway. Her most recent singles, "Two Step" and "Kentucky Dirty," push music boundaries and answer the question of what happens when you combine hot country, dance tracks and hip-hop beats.
Bundy currently can be seen on the CW's hit television program Hart of Dixie and FX's Anger Management, both of which are aired throughout the world. Her latest song release, "Kentucky Dirty" hit iTunes in November of 2013. The track references the singer's good ole Kentucky roots. For more information, visit www.laurabellbundy.com.
About the James Graham Brown Cancer Center:
The James Graham Brown Cancer Center is a key component of the University of Louisville Health Sciences Center. As part of the region's leading academic, research and teaching health center, the cancer center provides the latest medical advances to patients, often long before they become available in non-teaching settings. The JGBCC is a part of KentuckyOne Health and is affiliated with the Kentucky Cancer Program. It is the only cancer center in the region to use a unified approach to cancer care, with multidisciplinary teams of physicians working together to guide patients through diagnosis, treatment and recovery. For more information, visit our web site, www.browncancercenter.org.
The Julep Ball is sponsored in part by Advanced Cancer Therapeutics, Ashton Advertising, Bob Montgomery Dixie Honda, Boutique Serendipity, The Dahlem Company, Dillards, Enterprise, Headz Salon, Heaven Hill, Hubbuch & Co., InGrid Design, Jaust Consulting Partners, Jefferson County Sheriff's Office, KentuckyOne Health, Kroger, Louisville Magazine, Maker's Mark, Millennium: The Takeda Oncology Company, Morgan Stanley, MPI Printing, Nfocus, Old 502 Winery, Power Creative, Tito's Handmade Vodka, WAKY and WHAS11.
UofL adds three faculty members to Department of Orthopaedic Surgery
The UofL School of Medicine Department of Orthopaedic Surgery and University of Louisville Physicians Orthopedics have added three new faculty members: Rodolfo Zamora, M.D., Lonnie Douglas, M.D., and Jon Carlson, M.D.
"We are very excited about the growth in our practice and to be able to offer orthopedic specialty care in upper extremity, musculoskeletal oncology, sports medicine, hip and knee arthroplasty and foot and ankle," said Craig Roberts, M.D., M.B.A., chair of the Department of Orthopaedic Surgery.
Zamora, a native of Chile, specializes in orthopedic oncology and serves as chief of musculoskeletal oncology for UofL Physicians. His areas are benign bone and soft tissue tumors, bone and soft tissue sarcomas, metastatic disease procedures, orthopedic limb-salvage procedures, infections and orthopedic trauma.
"My professional philosophy is to be as close as possible to my patients. I love to have direct communication with them and referring physicians, medical oncologists and medical radiotherapists," Zamora said.
Zamora is actively involved in research, with interests including navigation systems in orthopedic oncological surgeries, surgical resections, pelvic and lower extremity, external fixation, osteosarcoma and cryosurgery/cryotherapy.
Douglas is a former college football player who specializes in sports medicine, orthopedic trauma and general orthopedics. He completed a sports medicine fellowship with world-renowned sports surgeon James Andrews, M.D., and has served as an associate team physician for the Washington Redskins and Auburn Tigers, as well as a consultant for the New Orleans Saints and Tampa Bay Rays. Douglas has been involved in research and presented nationally and internationally. He received the Brower-Harkess Research Award at the Kentucky Orthopaedic Society's annual meeting in 2013.
Carlson specializes in orthopedic trauma. He is a published researcher on a variety of orthopedic topics. His areas of expertise include complex fractures of the pelvis, hip, knee and extremities, as well as post-traumatic arthritis and degenerative arthritis of the hip and knee.
"Many patients with fractures about the hip and knee joints go on to develop post-traumatic arthritis. Joint replacement surgeries are often an important option with a proven track record and continue to be among the most successful operations in all of medicine," Carlson said.
"The key to providing excellent care is communication among all members of the health-care team, both inside and outside the hospital, as well as with the patient, their family and loved ones. I look forward to serving my patients."
Cancer immunotherapy to be discussed at next "Beer with a Scientist" event
Can we teach our own immune cells to kill cancer? Jason Chesney, M.D., Ph.D. of the James Graham Brown Cancer Center will discuss recent research at the next "Beer with a Scientist" program July 15
Jason Chesney, M.D., Ph.D.
One of the most promising areas of research in the fight against cancer is immunotherapy, or stimulating the body's own immune system to destroy cancer. Jason Chesney, M.D., Ph.D., a professor in the University of Louisville Department of Medicine and the deputy director of the James Graham Brown Cancer Center, is conducting clinical trials using checkpoint inhibitors as well as modified herpes virus in the treatment of melanoma with impressive results.
Chesney will speak at the next "Beer with a Scientist" event about immunotherapy research being conducted at UofL and elsewhere and treatments that may be available in the next few years.
"We finally understand how to activate the human immune system to clear cancer cells, having developed new classes of immunotherapies that dramatically improve the survival of cancer patients," Chesney said.
The program begins at 8 p.m. on Wednesday, July 15 at Against the Grain Brewery, 401 E. Main St. A 30-minute presentation will be followed by an informal Q&A session.
Five from UofL presenting at National Neurotrauma Society symposium
Scott Whittemore, Ph.D.
Three faculty members holding endowed positions, an associate professor and an instructor from the University of Louisville Department of Neurological Surgery will share their expertise this summer at the annual meeting of one of the nation's premiere organizations of brain and spinal cord injury specialists and researchers.
Neurotrauma 2015, the 33rd Annual Symposium of the National Neurotrauma Society, will be held in Santa Fe, N.M., June 28-July 1. The annual symposium is considered the primary scientific forum for exchanging information in the fields of both traumatic brain injury (TBI) and spinal cord injury (SCI).
On Sunday, June 28, assistant professor Enrico Rejc, Ph.D., will present Lumbrosacral Spinal Cord Epidural Stimulation for Standing After Chronic Complete Paralysis in Humans. At UofL, Rejc investigates the effects of different combinations of stimulation parameters, weight-bearing related sensory information and training on the modulation of the spinal neural networks, with the intent to promote the recovery of motor function for standing.
On Monday, June 29, Scott Whittemore, Ph.D., will chair the presentation on Genetic Dissection of Locomotor Circuitry. Speaking during the presentation will be David Magnuson, Ph.D., on Conditional Silencing Propriospinal Neurons: Hopping to a New Tune.
Whittemore is the Dr. Henry D. Garretson Chair in Spinal Cord and Head Injury Research and the scientific director of the Kentucky Spinal Cord Injury Research Center, considered one of the largest such centers in the nation. Magnuson is the Friends for Michael Endowed Chair in Spinal Cord Injury Research and also serves on the Symposium Program Committee organizing the 2015 event.
On Wednesday, July 1, Michal Hetman, M.D., Ph.D., will chair and Whittemore will co-chair the presentation, Cell Death is Still Alive, a look at the effect of cell death on TBI and SCI. Hetman is the Endowed Professor of Molecular Signaling and his research is concentrated on identification of the molecules controlling neural cell survival and growth. Instructor Sujata Saraswat-Ohri, Ph.D., will present one of the three sessions of the presentation, Targeting the Homeostatic Arm of the ER Stress Pathway Improves Functional Recovery After SCI.
"The Neurotrauma Annual Symposium has informative discovery, translational and clinical sessions and workshops, as well as programs for students and early career investigators," Whittemore said. "We are proud to bring the accomplishments of the University of Louisville into this discussion of the latest research and evidence-based medicine with our peers from throughout the country."
Single dose of HPV vaccine may prevent cervical cancer
Study shows one dose could be as effective as the three now recommended
Diane Harper, M.D., M.P.H., M.S.
A single dose of the human papillomavirus (HPV) vaccine Cervarix appears to be as effective in preventing certain HPV infections as three doses, the currently recommended course of vaccination. That is the conclusion of a study published today in The Lancet Oncology and co-authored by Diane Harper, M.D., M.P.H., the Rowntree Endowed Chair and professor in the Department of Family and Geriatric Medicine at the University of Louisville School of Medicine.
In the study, data from two large trials of the vaccine Cervarix were analyzed to compare the effectiveness of one, two or three doses of the vaccine in preventing HPV infection. In the trials, women were randomly chosen to receive three doses of Cervarix or a control vaccine. Although a number of the women received fewer than the three doses, follow-up tests were completed to evaluate the effectiveness of the vaccine in all the women for a period of four years.
The analysis determined the protection from one dose is similar to that achieved by three doses of the vaccine.
"These exciting findings address the fact that nearly two-thirds of people who get HPV vaccines do not get all three doses in a timely manner," said Harper, who was a principal investigator in one of the trials included in the analysis. "Knowing that Cervarix offers protection in one dose reassures public health agencies that they are not wasting money when most of their vaccines are given to those who never complete the three-dose series."
"Kentucky is one of the states that has not had a program in place to make Cervarix available to all of its citizens, and has very low three-dose completion rates of Gardasil, the other HPV vaccine," said Harper.
Worldwide, cervical cancer is the third most common cancer in women. HPV types 16 and 18 are responsible for about 70 percent of cervical cancers worldwide. These and other types of HPV cause a cancer precursor known as CIN 3.
"From all studies done, we see that Cervarix protects against CIN 3 caused by all HPV types at 93 percent efficacy," Harper said.
The study is published in The Lancet Oncology with the title, "Efficacy of Fewer than Three Doses of a HPV-16/18 AS04 adjuvanted Vaccine: a Meta Analysis of Data from the Costa Rica Vaccine Trial and the PATRICIA Trial."
Paying attention to rising ADHD rates at the next "Beer with a Scientist" program
Find out what's behind increased diagnoses at "Beer with a Scientist," Wednesday, June 10.
Paul Rosen, Ph.D.
Attention-Deficit/Hyperactivity Disorder (ADHD) has become one of the most common, controversial and important public health issues in the United States. Rates of ADHD have increased by more than 50 percent in the past 10 years, and the CDC reports that Kentucky has the highest rates of ADHD in the nation.
Is ADHD a real disorder or just a drug company scam? Why are the rates of ADHD going up so quickly, and why are they so high in Kentucky?
Paul Rosen, Ph.D., an assistant professor of psychology at UofL, will address these and other questions in the next "Beer with a Scientist" program: "Paying attention to increased ADHD rates: increased prevalence, over diagnosis or a better understanding?"
Rosen is the director of UofL's Research on ADHD and Children's Emotion Regulation (RACER) Lab, where his research focuses on emotion regulation and dysregulation in children with and without ADHD and emotional and behavioral problems in children with ADHD.
$50,000 childhood cancer research grant awarded to University of Louisville
The St. Baldrick's Foundation, a volunteer-driven and donor-centered charity dedicated to raising money for childhood cancer research, has awarded a one-year, $50,000 grant to the University of Louisville (UofL). This grant is one of 40 infrastructure grants awarded as part of the foundation's fall grant cycle, totaling more than $2.5 million and surpassing last year's total awarded during this same period.
The University of Louisville Department of Pediatrics' Division of Hematology, Oncology and Stem Cell Transplantation makes approximately 100 new diagnoses per year. One of the primary goals of the division is to offer novel therapies to allow patients to receive treatment within the region and not have to travel elsewhere. This grant will provide support to hire a nurse coordinator for neuroblastoma and sarcoma patients on clinical trials, providing them with additional access to those trials.
"The St. Baldrick's Foundation grant will help children diagnosed with cancer to receive the best care here in Louisville," explains Kerry Powell McGowan, M.D., pediatric oncologist at UofL. "With the grant we hope to help more children and their families stay close to home to get the treatment they need."
The grant to UofL is part of a series of grants that, combined with the more than $24.7 million awarded in July to fund cutting-edge research, brings the St. Baldrick's Foundation's funding total to more than $27.2 million awarded in 2014. Grants were awarded based on the need of the institution and its patients, anticipated results of the grant and local participation in St. Baldrick's fundraising events and activities.
"These grants are critically important to saving children's lives, and would not be possible without our dedicated volunteers and generous donors who believe kids deserve better than medicine is currently able to provide," said Kathleen Ruddy, chief executive officer for the St. Baldrick's Foundation.
To learn how you can get involved visit www.StBaldricks.org, and connect with St. Baldrick's on Facebook, Twitter,YouTube and Vimeo
About St. Baldrick's Foundation
The St. Baldrick's Foundation is a volunteer-driven charity committed to funding the most promising research to find cures for childhood cancers and give survivors long and healthy lives. St. Baldrick's coordinates its signature head-shaving events worldwide where participants collect pledges to shave their heads in solidarity with kids with cancer, raising money to fund research. Since 2005, St. Baldrick's has awarded more than $154 million to support lifesaving research, making the Foundation the largest private funder of childhood cancer research grants. St. Baldrick's funds are granted to some of the most brilliant childhood cancer research experts in the world and to younger professionals who will be the experts of tomorrow. Funds awarded also enable hundreds of local institutions to participate in national pediatric cancer clinical trials, and the new International Scholar grants train researchers to work in developing countries. For more information about the St. Baldrick's Foundation please call 1.888.899.BALD or visit www.StBaldricks.org.
New LGBT training incorporated into medical school curriculum
UofL School of Medicine is first in nation to provide core competencies program
Toni Ganzel, M.D., dean of the School of Medicine
The University of Louisville School of Medicine will serve as the nation's pilot site for training future physicians on the unique health care concerns and issues encountered by people who are lesbian, gay, bisexual, transgender (LGBT), gender nonconforming or born with differences of sex development (DSD).
"We are very excited to serve as our nation's learning ground in training the next generation of physicians in meeting the unique health care needs of our LGBT and DSD-affected population," said Toni Ganzel, M.D., dean of the UofL School of Medicine. "Every segment of our population brings its own set of health care issues and concerns. As we strive to provide the highest quality training possible, it is a privilege to model that educational experience for our colleagues throughout the nation."
UofL will spend the next few months developing the formal curriculum and begin the pilot program in the 2015-16 academic year, with full integration into the curriculum in 2016-17.
People who are LGBT, gender nonconforming or born with DSD often experience challenges when seeking care in doctors' offices, community clinics, hospitals and emergency rooms. Research shows that these health disparities result in decreased access to care or willingness to seek care, resulting in increased medical morbidity and mortality for LGBT and DSD-affected patients.
All aspects of patient care, from the intake forms and interaction with caregivers in the outpatient office to interactions during critical illness, require an accepting, informed, patient-centered approach from all physicians in order to improve the adverse health outcomes seen in this patient population.
In early November, the Association of American Medical Colleges identified 30 competencies that physicians must master. These competencies fall under eight domains of care critical to training physicians, including patient care, knowledge for practice, practice-based learning and improvement, interpersonal and communication skills, professionalism, systems-based practice, interprofessional collaboration and personal and professional development.
This competency-based framework will allow medical educators to integrate the new guidelines into existing curricula more easily and encourage faculty and health care professionals to move away from thinking of patients in these groups as separate from the general patient population.
"As a university, we continue to be a leader in recognizing the importance of understanding our diverse population and working to meet the varying needs," said Brian Buford, assistant provost for diversity and director of the LGBT Center at UofL.
UofL School of Medicine will be assisted in this curriculum integration project by two of the primary authors of the competencies, Jennifer Potter, M.D., Harvard School of Medicine, and Kristen Eckstrand, Ph.D., Vanderbilt University School of Medicine and fourth-ear medical student. Additionally, John Davis, M.D. from The Ohio State University and the AAMC Group on Diversity & Inclusion LGBT Issues Representative also will assist in the project.
Underrepresented undergraduate students gain medical research experience in summer program
Students will present research at poster session Wednesday, August 3
Kayla Massey and Maura Fordham
This summer, Kayla Massey is using an infrared spectrometer at the University of Louisville to determine how the structure of a lipid called meibum found in the eyelid affects tears in the eye. Massey, who will be a junior at Howard University this fall, is spending the summer in Louisville to gain experience working in a research lab that will help her when she applies to a post-graduate program.
"I've done research in biology before, but this is centered around the lipids in the eye so it is a lot more about organic chemistry. It is good for me because I had never done any chemistry research before," Massey said.
Massey is one of 10 students participating in the Summer Undergraduate Experiences in Biomedical Research program, directed by Irving Joshua, Ph.D., chair of the Department of Physiology at UofL. The program, supported by a grant from the National Institutes of Health, allows students who are economically disadvantaged, the first in their family to attend college, underrepresented minorities or from underserved areas to spend 10 weeks working in research labs with faculty mentors in areas such as diabetes, kidney disease and heart disease.
"Our goal is to get more underrepresented minority and disadvantaged students involved in research, doctoral programs and medicine. This experience will give them exposure to clinical research that can help them in their careers," Joshua said.
The Association of American Medical Colleges and the National Academy of Medicine support the idea that a diverse workforce in health care and biomedical research will serve to reduce health disparities in the United States.
Massey, a biology major who hopes to attend medical school and become a surgeon, is being mentored at UofL by Douglas Borchman, Ph.D., professor in the Department of Ophthalmology & Visual Sciences. His research focuses on dry eye and cataracts related to diabetes.
"I am interested in diabetes and high blood pressure. Dr. Borchman is doing work with the effects that glucose has on lenses," Massey said. "I think it's opened my eyes to more about science and medical research in general."
Borchman hopes to encourage Massey and other students in the program to pursue graduate study or medicine by engaging them in the research experience.
"The program can lead to them going on to grad school, which is great," Borchman said. "I enjoy seeing the spark in the students, showing them that research is fun and not tedious. I give them responsibility and a long leash but don't let them stray too far. They are young and enthusiastic and it is fabulous."
One of Borchman's former summer undergraduate mentees, Samiyyah Sledge, is now a Ph.D. student at UofL in physiology and biophysics with a concentration on the eye. Sledge said her experience as a summer undergraduate in 2014 piqued her interest in this area of research and introduced her to opportunities in graduate programs.
"This lab fostered and developed my love for the eye and for research in general," Sledge said. "The exposure and experiences I gained here influenced my decision to join the physiology Ph.D. program. In addition, Dr. Borchman himself has been a great and supportive mentor to me."
Maura Fordham, another program participant this summer, will attend UofL this fall as a biology major, after transferring from Jefferson Community and Technical College. Fordham is working in the lab of Utpal Sen, Ph.D., associate professor in the Department of Physiology, whose research focuses on kidney disease.
"We are looking into diabetic nephropathy regulating Micro RNA 194 through the synthetic drug GYY 4137," Fordham said. "It's taught me technique and how you handle yourself in a lab. I've gained an incredible amount of knowledge this summer from everyone in Dr. Sen's lab. I know this experience will help me as I continue as an undergrad and eventually as a medical student."
Sen said the summer students he mentors often are successful in applying to post-graduate programs.
"I want to get summer students in as undergraduates to get them interested in a research career that is both fun and challenging, yet rewarding," Sen said. "Some go on to do a master's or PhD program, and many of them are getting into medical school. It is a good basic research experience for them. They get used to the faculty and the programs our university offers and it helps them get into those programs. When these students are successful in their future careers, everyone benefits – the department, the university, the candidate and the mentor. We need more of these young minds to get involved in active biomedical research to advance the field for human well-being."
Joshua said students typically participate following their sophomore or junior year of college and are paired with investigators working in areas of interest to them. TheprogramatUofLhas been supported by a grant from the National Heart Blood and Lung Institute, part of the National Institutes of Health, since 2006 and is open to students attending colleges in and outside of Kentucky. Student selection is based on their grades, an essay describing their interest in scientific and biomedical research, and how well their areas of interest mesh with available mentors at UofL.
To conclude the program, the students will give a five to 10-minute presentation of their research and present posters along with other summer research program participants on Wednesday, August 3, from noon until 3 p.m. in the Kosair Charities Clinical and Translational Research Building, 505 S. Hancock St.
UofL leads first research team to identify AF1q protein associated with multiple myeloma, extramedullary disease
William Tse, M.D.
A group of researchers from the University of Louisville, Japan and Austria is the first to identify a protein, AF1q, associated with multiple myeloma and a condition that occurs in approximately one-fourth of very aggressive multiple myeloma, extramedullary disease or EMD.
The group will present their findings at the European Hematology Association's 21st Congress, June 10-12, in Copenhagen, Denmark. Their presentation is entitled "High expression of AF1q is an adverse prognostic factor and a prediction marker of extramedullary disease in multiple myeloma."
William Tse, M.D., the Marion F. Beard Endowed Chair in Hematology and chief of the Division of Blood and Bone Marrow Transplantation at UofL, was senior investigator on the project, working with researchers in Tokyo and Vienna.
Multiple myeloma is one of four types of myeloma and the most prevalent. It is a form of blood cancer that develops in the bone marrow. In multiple myeloma, normal plasma cells transform into malignant myeloma cells and produce large quantities of toxic abnormal immunoglobulin called monoclonal protein that can damage multiple organs. The monoclonal protein produced by the myeloma cells interferes with normal blood cell production.
The American Cancer Society estimates that 30,330 new cases of multiple myeloma will occur in the United States in 2016 and about 12,600 people will die from it.
Approximately 25 percent of patients with multiple myeloma also simultaneously develop extramedullary disease. This disease occurs when the myeloma cells form tumors outside of the bone marrow in the soft tissues or organs of the body. The prognosis of myeloma patients with EMD behaves like other metastatic cancers and is extremely poor because its clinical course is veryaggressive, Tse said.
"We know that multiple myeloma with EMD involvement has an extremely poor outcome," Tse said. "However, not much is known about the mechanism in which EMD progresses."
The group looked at an oncogene, AF1q discovered in Tse's lab, which is expressed in hematological cancer cells and is known to be related to multiple myeloma. Its presence indicates a poor prognosis for the patient.
Tse and the team analyzed the degree of expression of AF1q in 117 patients with multiple myeloma. They found that EMD was present in 25 percent of patients with a low AF1q expression and in 44.7 percent of patients with a high AF1q expression.
"We found that the incidence of EMD was significantly higher in patients with high expression of AF1q than those with low expression," Tse said. "The significance of this finding gives us a tentative approach to target this marker and could lead to new therapies for this subtype of myeloma."
Tse's research team included Drs. Shotaro Hagiwara, the lead author and chief of hematology, and Sohtaro Mine of the National Center for Global Health and Medicine in Tokyo, Ana-Iris Schiefer of the Medical University of Vienna and Lukas Kenner of the Ludwig Boltzmann Institute for Cancer Research and Medical University of Vienna. The study patient cohort was organized by Hagiwara.
Tse practices with University of Louisville Physicians-Medical Oncology/Hematology and with UofL's James Graham Brown Cancer Center, a part of KentuckyOne Health.
Is your home a potential pet poison pit? Veterinary pathologist on common pet toxins at Beer with a Scientist, Feb. 13
Kate Baker, D.V.M., M.S. and Roo
A number of potentially life-threatening toxins found in many households can seriously harm your furry best friend. Even things humans safely ingest every day can be fatal to pets.
At the next Beer with a Scientist, Kate Baker, D.V.M., M.S., a veterinary clinical pathologist with Blue Pearl Specialty and Emergency Veterinary Hospital, will explain why some seemingly harmless substances actually are very dangerous for our animals. She also will address what veterinarians do to save pets when they ingest a toxin.
"Many of us share our homes with pets, and sometimes, they eat things they shouldn't. While some of these things may be harmless, others can seriously harm pets, even things people consume every day with no issues, from common medications such as Tylenol or ibuprofen, to foods we eat every day like onions and grapes," Baker said.
Baker's talk will begin at 7 p.m. on Wednesday, Feb. 13, at Holsopple Brewing, 8023 Catherine Lane, Louisville, 40222. A 30-minute presentation will be followed by an informal Q&A session.
Upcoming Beer with a Scientist dates: March 13, April 17, May 15.
Metabolite produced by gut microbiota from pomegranates reduces inflammatory bowel disease
UofL researchers share understanding of how Urolithin A and its synthetic reduce inflammation and improve gut barrier
Illustration showing tightening of gut barrier cells and reduced inflammation due to UroA
Scientists at UofL have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease (IBD). Millions of people worldwide suffer from IBD in the form of either ulcerative colitis or Crohn's disease, and few effective long-term treatments are available.
The researchers at UofL have determined that Urolithin A (UroA) and its synthetic counterpart, UAS03, mitigate IBD by increasing proteins that tighten epithelial cell junctions in the gut and reducing gut inflammation in animal models. Tight junctions in the gut barrier prevent inappropriate microorganisms and toxins from leaking out, causing inflammation characteristic of IBD. Preclinical research published today in Nature Communications shows the mechanism by which UroA and UAS03 not only reduce inflammation and restore gut barrier integrity, but also protect against colitis.
"The general belief thus far in the field is that urolithins exert beneficial effects through their anti-inflammatory, anti-oxidative properties. We have for the first time discovered that their mode of function also includes repairing the gut barrier dysfunction and maintaining barrier integrity," said Rajbir Singh, Ph.D., a postdoctoral fellow at UofL and the paper's first author.
Venkatakrishna Rao Jala, Ph.D., assistant professor of microbiology and immunology at UofL, led the research, conducted by Singh and other collaborators at UofL, the Institute for Stem Cell Biology and Regenerative Medicine (inStem) in Bangalore, India, the University of Toledo College of Medicine and Life Sciences, and Dalhousie University in Nova Scotia. Jala, Singh and other researchers at UofL have been investigating how metabolites produced by the human microbiota – bacteria, viruses and fungi that inhabit the human body – affect many areas of health. By understanding the effects of specific metabolites, they hope to use them directly as therapeutic agents in treating disease.
It has been reported that the microbe Bifidobacterium pseudocatenulatum INIA P815 strain in the gut has the ability to generate UroA from ellagic acid (EA), a compound found in berries and pomegranates. Variations in UroA levels, despite consumption of foods containing EA, may be the result of varied populations of bacteria responsible for the production of UroAfrom one individual to another, and some individuals may not have the bacteria at all. While encouraging natural levels of UroA in the gut by consuming the appropriate foods and protecting populations of beneficial bacteria should have positive health effects, the researchers believe the use of the more stable synthetic UAS03 may prove to be therapeutically effective in cases of acute colitis. Further experiments and clinical testing are needed to test these beliefs.
"Microbes in our gut have evolved to generate beneficial microbial metabolites in the vicinity of the gut barrier," Jala said. "However, this requires that we protect and harbor the appropriate gut microbiota and consume a healthy diet. This study shows that direct consumption of UroA or its analog can compensate for a lack of the specific bacteria responsible for production of UroA and continuous consumption of pomegranates and berries."
Haribabu Bodduluri, Ph.D., professor of microbiology and immunology at UofL and an author of the article, said another key finding of the research is that UroA and UAS03 show both therapeutic and protective effects. Administration of UroA/UAS03 after the development of colitis reverses the condition and administration prior to development of colitis prevents it from occurring.
This research was facilitated by funding from the National Cancer Institute to Jala and the Center of Biomedical Research Excellence (CoBRE), established at UofL in 2018 with funding from the National Institute of General Medical Sciences.
The article, "Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway," is available on the web site, Nature Communications (DOI: 10.1038/s41467-018-07859-7). This research was supported by the National Institutes of Health, U of L, Rounsavall Foundation, The Jewish Heritage Fund for Excellence Research Enhancement Grant and the James Graham Brown Cancer Center. The Department of Biotechnology and the Institute for Stem Cell Biology and Regenerative Medicine (inStem), India, also supported the work.
Several authors hold a patent application related to this technology.
UofL's Bolli helps raise profile of major medical journal
Impact factor of 'Circulation Research' jumps
Roberto Bolli, M.D.
A University of Louisville physician and researcher has helped raise the profile of a leading medical journal to an all-time high.
The journal Circulation Research, edited by UofL's Roberto Bolli, M.D., has achieved its highest-ever "impact factor," a measure of its importance in the medical field. Circulation Research is an official journal of the American Heart Association and is considered the world's leading journal on basic and translational research in cardiovascular medicine. Its impact factor, calculated yearly and just announced for 2016, places it among the top 2 percent of medical journals.
Bolli, chief of Cardiovascular Medicine at the UofL School of Medicine and UofL Physicians, took over as editor of the journal in 2009, and has worked to raise the journal's profile since. He also serves as director of UofL's Institute of Molecular Cardiology and scientific director of the Cardiovascular Innovation Institute.
The impact factor (IF) is a measure of the frequency with which the average article in a journal has been cited in other articles and medical literature in a particular year. The more cited a journal is, the more "impact" it has on the community. The impact factor for Circulation Research is 13.96. When Bolli took over as editor-in-chief, it was 9.4. From 2015 to 2016 alone, the impact factor jumped 2 points.
"Just as a major newspaper helps shape public opinion, the journal Circulation Research has an impact on what is considered important," Bolli said.
Impact factors are calculated by the Institute for Scientific Information and tracked by the Journal Citation Reports for more than 12,000 journals. Factors range from 0 to more than 10; only 2 percent of journal titles have a 2016 impact factor of 10 or higher. Approximately two-thirds have a 2016 impact factor equal to or greater than 1. Those with very high impact factors include such notables as The New England Journal of Medicine and Science.
Since becoming editor-in-chief, Bolli and the Circulation Research editorial board have made dozens of changes at the journal to help increase its quality and impact factor.
"That's a huge jump," he said. "Four-point-five points in seven years is unprecedented. It's very hard, as there are an increasing number of medical journals competing for articles."
Bolli noted that the jump is even more meaningful given that Cardiovascular Research only publishes research into the cardiovascular system, where other journals publish multiple or all areas of medical research. "Our focus is much narrower, yet despite this the impact factor has gone up," he said.
He said the impact factor of a journal is one of the main elements authors look at when deciding where to submit their best work. A journal's ability to receive high-quality work for publication depends on how high its impact factor is, he said.
"It is a big deal to have a paper published in Circulation Research, and it is considered a significant achievement," Bolli said.
The journal is widely read in the field, and its website receives more than 10 million hits per year. It receives approximately 2,000 submissions of articles per year, he said.
Bolli was selected as the journal's editor-in-chief from more than 40 candidates, all leading scientists from top medical schools around the country. He called his selection an "incredible honor."
He said that not only was it an honor for him personally, it was notable for the University of Louisville, as having the editor of a leading medical journal housed at the School of Medicine raises its profile internationally.
"I view it as my most important contribution to science, more than anything else I've done," he said. "The journal helps steer the field of cardiovascular research."
Membership on the journal's editorial board is also very competitive, and is reserved for the top cardiovascular researchers in the world. "It is an honor just to be included," Bolli said.
One of the changes he and the board made was raising the bar for article acceptance. Only 7 percent of articles submitted are now accepted, compared with 16 percent before.
"If we select an article to be published, it is truly novel, methodologically immaculate, and likely to be important for others," Bolli said.
Another change was an acceleration of the review process, making acceptance of articles more efficient. He said the journal now has the shortest turnaround time in the field. The journal also was opened up to clinical studies involving patients, and has launched more than 20 new article categories.
For Bolli, seeing the journal rise in prominence after years of hard work is meaningful not just for himself, but for the patients that ultimately benefit from research in the field.
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This dark, imaginative comedy follows the eccentric and dysfunctional members of the Flowers family. Maurice, author of a children's book series, and his wife, Deborah, a music teacher, have a troubled relationship. Maurice struggles with inner demons and dark secrets, while Deborah becomes increasingly suspicious that Maurice is in a secret relationship with Shun, the man who illustrates Maurice's books. The couple are parents to 25-year-old maladjusted twins, who are both competing for the attention of a neighbor.
If you like Flowers you may also like these shows.
While a comedy, it addresses mental illness surprisingly well.


After storming through a generally soft patch of schedule for a 4-0 mark two weeks ago and then fighting through a gauntlet of tough opponents for a 3-1 record last week, this week sees the Hurricanes with a lighter three-game schedule and more middle of the road match ups.
The week kicks off at Madison Square Garden against a New York Rangers team that seems to be in an odd in between state having traded off a few veterans like a rebuilding team might do but still being led by an elite veteran goalie and a group that includes a good chunk of the old guard. Regardless of the state of the Rangers who enter with an 18-20-7 mark, Madison Square Garden has always been a tough building for the Canes. Here is hoping that times are changing in that regard.
On the Hurricanes side of the puck, the key is not to exhale or become overconfident. Many things have gone right over the recent run. Last week the hockey gods tossed in a bunch of bonuses with two opposing goals disallowed after replays and some crazy series of own goals or deflections where the puck found the net after going off an opposing defenseman. On the 'earned' side of the ledger, the top line hit a scoring burst, the team is suddenly four lines deep and the defense and goaltending has continued to be solid. But at the core of the second half of the positive run beating good teams has been the team's consistent level of compete across the entire roster and 60 minutes. Critical is not losing track of that.
My watch points for Tuesday's game follow.
Since Micheal Ferland rejoined Sebastian Aho and Teuvo Teravainen, the line has been red hot and the flag bearer scoring-wise. Here is hoping that the group can stay hot and carry the team a bit further, as it tries to take the last few steps to play their way all the way back up to the playoff cut line. The Rangers no longer have a pure shutdown defense pairing, so the door seems to be open for another big night for Aho and company. On Tuesday, I will be watching to see if they can continue their run.
Confidence can be a funny thing. Winning seven out of eight and the mojo that comes with it is generally a positive. But oftentimes the end of a good run comes when confidence boils over into complacency and shifting from fighting for wins to just assuming they will come. On the front part of the wins streak, the Hurricanes were more faking it to try to make it with a couple decent but incomplete efforts against weak teams that were good enough for wins. But this past week saw the team string together a series of a solid 60-minute efforts even in the loss to Tampa Bay. On Tuesday, I will be watching to see if the team can avoid the dreaded exhale loss and can instead keep the pedal down.
The power play has truly been a Jekyl and Hyde case over the past 4-5 weeks. The group looked completely inept and could not even seem to gain the offensive zone only a few weeks back. More recently, the power play has been a positive and big contributor to the scoring and winning run. Especially on the road, winning the special teams battle can often be the difference between winning and losing. On Tuesday night, I will be watching to see if the special teams can again lead the way.


The easiest way to spot a scam is to take a step back and consider whether the deal being offered is just too good to be true. You'll find it normally is.
If you've received any offer to buy your motorcycle without the buyer wanting to view it, and it's worth more than £500, then alarm bells should start ringing.
Would you buy a private secondhand bike without at least taking a look at it?
If you receive any emails from foreign buyers offering to pay by money transfer, then it's almost certainly a scam attempt. Unless you've got a particularly rare classic, it's unlikely to be interesting enough to be worth them shipping a normal motorcycle around the world.
You'll find that the offer normally involves them paying more than the bike is worth, sending a shipping agent, and asking you to send the difference back to them. That's because the money transfer will show in your account before it has actually cleared, and once you've sent the difference, you'll find that the money transfer has bounced and you're out of pocket.
If you're taking any payment other than cash, phone your bank to check exactly how long before payments will be cleared and don't let go of the bike until you are sure they have cleared.
The full asking price in cash is also the best deposit for allowing a test ride. If you've got any doubts at all, don't let the bike out of your sight. A bike/car left as a deposit might turn out to be stolen, and a friend/wife or family with them might end up doing a runner.
Be very wary of international buyers.


text:
EMOIS Nancy 2011 - Comment identifier et valoriser un transfert d'activité en cardiologie.
Comment identifier et valoriser un transfert d'activité ? Application à une activité de cardiologie.
Auteur(s) : C. Segouin1, 2, A. Leenhardt 3 , A. Dozol1, C. Duteil1, V. Barbier1 , A. Cohen –Solal3
1 Service de Santé Publique et Economie de la Santé, groupe hospitalier Lariboisière-Fernand Widal, Assistance Publique- Hôpitaux de Paris
2 Wilson Centre for Research in Education, Faculté de médecine, Université de Toronto, Canada.
3 Service de Cardiologi
9. Emil Sax: The Recluse from Voloska

Author(s): Eugen-Maria Schulak
11. Money Makes the World Go Round: The Monetary Theory of the Business Cycle
12. Joseph A. Schumpeter: Maverick and Enigma
14. The Austrian School's Critique of Marxism
15. The Consequences of War: The Imminent Collapse
16. Between the Wars: From Re-formation to Exodus
18. Friedrich August von Hayek: Grand Seigneur on the Fence
19. Other Members of the Younger Austrian School
20. Praxeology: A New Start from Ludwig von Mises
21. Friedrich August von Hayek's Model of Society and His Theory of Cultural Evolution
22. The Entrepreneur
24. The Renaissance of the Old 'Viennese' School: The New Austrian School of Economics
Precast 19: Exocrine & Endocrine System 2
ENHANCED podcast on human pheromones, the pituitary gland, and the thyroid gland and related hormones.
L193Thema05_Kulturelles_Zweites_Freizeit_2
Whiteboards from my second Elluminate tutorial on Leisure and Hobbies. Aims to develop aspects covered in the preceding tutorial. For face to face use, I have included PNG images. (Interactive Inversion activity based on similar activity by Suzanne Winchester).
My Bookmarks.
6.3 The architecture
What is 'e-commerce'? This unit will look at typical application areas including the internet, supply chain management and online auctions. It will also help you to understand the underlying technologies used to implement e-commerce applications before looking at some of the problems that can be encountered when developing distributed e-commerce systems.
Except for third party materials and otherwise stated (see http://www.open.ac.uk/conditions terms and conditions), this content is made available under a http://creativecommons.org/licenses/by-nc-sa/2
Winter Lecture Series - 2010: Achieving a tobacco-free New Zealand by 2020 - why it must happen and
The Māori Affairs Select Committee's investigation into the tobacco industry has invigorated the debate about becoming tobacco-free, and placed New Zealand at the forefront internationally of reducing the impact of tobacco on health in a similar manner to our nuclear-free stance in the 1980s. Professor Edwards investigates the need for a tobacco-free New Zealand and explores the best options for achieving the 2020 vision. Held September 30, 2010.
State Data Map
Information can be represented in many ways; this applet allows the user to represent data about the states using color. The state with the highest data value is darkest; other states are shaded proportionally. Several sets of data are already entered and available for examination: state population, land area, representatives in Congress, gasoline usage, and more. Users can eliminate the data from any state in order to note the consequences, or enter their own data. A box plot and table accompan
Author(s): NCTM
Copyright 2000 - 2009 National Council of Teachers of Mathematics,http://illuminations.nctm.org/termsofuse.aspx
neoK12: Geometry
A set of 15 videos showing brief lessons on geometry definitions (polygons, angles, tangents) and basic applications (finding areas, using the Pythagorean theorem). In these 2 to 10-minute lessons, a teacher uses blackboard drawings and clear explanations to deliver mini-tutorials.
Author(s): Creator not set
2009 NeoK12. All rights reserved.

redpajama_set_name: RedPajamaCommonCrawl


text:
Afton Copeland Spiegel, Political Reporter|December 18, 2020
Graphic by Bella Tiner '21.
As President-Elect Joe Biden announces his cabinet picks, and Dr. Jill Biden, and Vice President-Elect Harris announce their staff, the Mayfield Crier will be updating this page with information on each of the new members of the administration.
As he builds his cabinet, Biden said he hopes to create a group that looks like the United States. Thus far, Biden has announced key players with experience to tackle the challenges his administration will face come inauguration day on January 20, 2021. Biden's Chief of Staff Ron Klain is worthy to handle the COVID-19 pandemic after he coordinated the White House response to the Ebola Epidemic. His chosen Medical Advisor Dr. Anthony Fauci has been one of the public faces to the United States response to the pandemic and will continue this role in the Biden Administration. The President-Elect's cabinet all have qualities making them apt to serve the citizens of the United States.
WHITE HOUSE SENIOR STAFF
CHIEF OF STAFF-Ron Klain
A longtime public servant, Klain has been tapped for incoming Chief of Staff, having worked with President-Elect Biden since the late 1980's. He served as then-Vice President Biden's Chief of Staff from 2009 to 2011. Klain first worked alongside Biden in '88 as an advisor to his senate campaign and later served as chief counsel to the Senate Judiciary Committee from 1989 to 1992. He also worked with the Obama administration as the Ebola Response Coordinator making him suitable to address the COVID-19 pandemic. He is a graduate of Georgetown University and Harvard Law School.
DEPUTY CHIEF OF STAFF-Jen O'Malley Dillion
The Biden-Harris Campaign manager Jen O'Malley Dillion has been appointed the Deputy Chief of Staff after a successful 2020 campaign. O'Malley Dillon was previously the campaign manager for Beto O'Rourke and deputy campaign manager for reelection of former President Barack Obama. She has also served as the executive director of the Democratic National Committee and as the battleground states director of the 2008 Obama campaign. She is a graduate of Tufts University in Massachusetts.
DIRECTOR OF THE WHITE HOUSE OFFICE OF INTERGOVERNMENTAL AFFAIRS-Julie Rodriguez
Julie Rodriguez was named as the incoming director of the White House Office of Intergovernmental Affairs. The position she holds will ensure proper collaboration between state, local, and tribal governments with the federal government. She has served as both the deputy campaign director of the Biden Harris Campaign and the traveling chief of staff for then-Senator Kamala Harris' presidential campaign. Rodriguez was the special assistant to President Obama and previously served as the Director of Programs at the Cesar E. Chavez Foundation. She is a Californian and a graduate of the University of California, Berkeley.
DIRECTOR OF OVAL OFFICE OPERATIONS-Annie Tomasini
Previously the Deputy Press Secretary for Vice President Biden, Annie Tomasini will be serving as the Director of Oval Office Operations. Tomasini will manage the President's schedule, private engagements as well as who has immediate access to the Commander in Chief. She worked with President-Elect Biden for over 10 years as his Press Secretary during his time in the Senate. She was also the Senior Director of State, Local, and Community Relations and Community Outreach at Harvard University. Tomasini is from Massachusetts and a graduate of Harvard University.
WHITE HOUSE SOCIAL SECRETARY-Carlos Elizondo
After serving as the Vice President's Social Secretary for eight years, Carlos Elizondo will be the next White House Social Secretary. Elizondo will manage official White House events and oversee the residence. He is experienced in the position after managing several events for President-Elect Biden and Dr. Jill Biden during his time in the Obama Administration.
DIRECTOR OF THE WHITE HOUSE OFFICE OF PRESIDENTIAL PERSONNEL-Cathy Russell
After serving as the Vice Chair of the Biden Harris Campaign, Cathy Russell has accepted the position of Director of the White House Office of Presidential Personnel. Russell will hire those who work in the West Wing and will provide the President with the best candidates possible. Before the campaign, she served as a resident fellow at the Institute of Politics at the Kennedy School of Government at Harvard University. She served the Obama Administration for all eight years in the White House and State Department. She also held the position of US Ambassador for Global Women's Issues. She is a graduate of Boston College and George Washington University Law School.
SECRETARY OF STATE-Antony Blinken
Antony Blinken is the next Secretary of State for the Biden Administration. He has experience in the position, serving as Deputy Secretary of State for former President Obama. As the deputy, he worked on the Global Refugee Crisis and built strong relationships with countries. During President-Elect Biden's campaign, he served as the foriegn policy advisor. He has worked in politics since the 1990's as a member of former President Clinton's National Security Staff. He is a graduate of Harvard College and Columbia Law School.
SECRETARY OF HOMELAND SECURITY-Alejandro Mayorkas
Alejandro Mayorkas will be the first immigrant and Latino to lead Homeland Security. He served as Deputy Secretary of the department from 2013-2016 where he managed the Ebola virus crisis. He led the U.S. Citizenship and Immigration Services from 2009-2013. He began his career as a public servant in the position of Assistant United States Attorney General in the Central District of California.
DIRECTOR OF NATIONAL INTELLIGENCE-Avril Haines
Avril Haines will be the first woman to be the Director of National Intelligence. She was the Deputy National Security Advisor from 2015-2017 and was the Assistant to former President Obama. In 2013, she became the first woman to hold the position of the Deputy Director of the Central Intelligence Agency. She previously worked with then-Senator Biden as the Deputy Chief Counsel to the Senate Foreign Relations Committee. She attended the University of Chicago and Georgetown University Law Center.
U.S. AMBASSADOR TO THE UNITED NATIONS-Linda Thomas-Greenfield
Ambassador Thomas-Greenfield is Biden's U.S. Ambassador to the United Nations. She has been a public servant for over 35 years in several foreign relations positions. She held the position of Assistant Secretary for the Bureau of African Affairs during the second term of the Biden Administration. Previous to this, she held the position of the Director General of the Foreign Service and Director of Human Services for a year. She has held postings in over four continents and specializes in African Affairs. She attended Louisiana State University. She also holds two degrees from the University of Wisconsin.
LAW REPRESENTATION
WHITE HOUSE COUNSEL-Dana Remus
Dana Remus is the incoming White House Counsel of the Biden administration in which she advises the President and his staff on legal matters. She has also worked at the Obama Foundation as their general counsel and was Deputy Assistant to former President Obama. She was a professor of Law at the University of North Carolina Law School and clerked for Supreme Court Justice Alito. She is a graduate of Harvard College and Yale Law School.
COUNSELOR TO THE PRESIDENT-Steve Ricchetti
After being the Chairman of the Biden Harris Campaign, Steve Richetti will serve as the counselor to the President during the next administration. He has previously been the Assistant to the former President Obama and the Chief of Staff to President-Elect Biden when he served as Vice President. He was also Deputy Chief of Staff to former President Clinton and Deputy Assistant to the President for Legislative Affairs during the Clinton Impeachment Hearings. He is a graduate of both Miami University and George Mason University of Law as a native of Ohio.
SECRETARY OF THE TREASURY-Janet Yellen
Janet Yellen has been nominated as the Secretary of the Treasury and if appointed, will be the first woman to run the department in the 231 years since its founding. She was the Vice Chair of the department from 2010 to 2014 and was the Chair of the Economic Council to former President Bill Clinton. She graduated from Brown University and has a Ph.D from Yale University.
DIRECTOR OF THE OFFICE OF MANAGEMENT AND BUDGET-Neera Tanden
Neera Tanden, if appointed, will be the first woman of color to be the Director of the Office of Management and Budget while she currently serves as the President of the Center of American Progress. Tanden specializes in developing policy for low-income families needing assistance after her experience as a young child with a single mother living on food stamps and Section 8 housing vouchers. She served as the Director of Domestic Policy in the Obama Biden Administration. She attended both UCLA and Yale Law School.
DEPUTY SECRETARY OF THE TREASURY-Wally Adeyemo
Wally Adeyamo is the first African-American nominee for Deputy Secretary of the Treasury and is the current President of the Obama Foundation, a non-profit founded by former President and First Lady Obama. He served as Obama's senior economic advisor and also has advised businesses in the private sector. Adeyemo was born in Nigeria and raised in the Inland Empire of Southern California. He attended the University of California at Berkeley and Yale Law School.
HUMAN SERVICES AND HEALTH
DIRECTOR OF HEALTH AND HUMAN SERVICES-Xavier Becerra
California's very own Attorney General Xavier Becerra is nominated for the Director of Health and Human Services. Considered a candidate for the United States Attorney General, Becerra was selected for his position because of his consistent battle to fight for Obamacare. He served 12 terms as a United States Representative and was the Chair of the House Democratic Caucus. Originally from Sacramento, Becerra was the first of his family to graduate from college. He attended Stanford University and its Law School.
SURGEON GENERAL-Dr. Vivek Murthy
Dr. Vivek Murthy, if confirmed, will be the Surgeon General for the second time after sitting in the same position during the Obama Administration. He is the Co-chair of the President Elect's COVID-19 advisory board and he has also managed the Ebola and Zika Virus during his time as Surgeon General. His experience makes him suitable to respond to the pandemic. Murthy was born in England and raised in Miami, Florida. He attended Harvard College, the Yale School of Management and the Yale School of Medicine.
DOMESTIC DEPARTMENT
SECRETARY OF HOUSING AND URBAN DEVELOPMENT-Marcia Fudge
In a surprising appointment, Representative Marcia Fudge is the Biden Administration's Secretary of Housing and Urban Development. The announcement comes as a shock to many because of Fudge's passion for agriculture and feeding those who need it. Fudge was appointed to congress in 2008 to represent Ohio's 11th District. Before that, she was the first African-American woman mayor of Warrensville Heights, Ohio. She attended Ohio State University and Cleveland University, earning degrees in business and law school.
SECRETARY OF AGRICULTURE-Tom Velsick
Tom Velsick will be serving as the Secretary of Agriculture for a second administration after holding the same position in the Obama administration. Previously, he was a two-term governor of the state of Iowa. He continuously campaigned for the President-Elect since the Iowa Caucus during the primaries. In the 2008 election, he planned to run but dropped out in early 2007 and co-chaired Secretary of State Hillary Clinton's campaign. He attended Hamilton College and Albany Law School.
SECRETARY OF VETERANS AFFAIRS-Denis McDonough
Previously the Chief of Staff to President Obama, Denis McDonough will be the next Secretary of Veterans Affairs. He also served as the Principal Deputy National Security Advisor from 2010 to 2013. He has worked as a Congressional Staffer prior to his work in the Obama Administration. Born and raised in Minnesota, he attended St. John's University and went to graduate school at Georgetown University.
UNITED STATES TRADE REPRESENTATIVE-Katherine Tai
Katherine Tai is the new United States Trade Representative after serving as the head attorney on the Committee of Ways and Means, handling matters of international trade. She was the Chief Counsel at the World Trade Organization and handled matters of United States trade with China. She is a graduate of Yale University and Harvard Law School.
DIRECTOR OF THE DOMESTIC POLICY COUNCIL-Ambassador Susan Rice
Ambassador Susan Rice has been appointed the Director of the Domestic Policy Council after a life of public service. She was the National Security Advisor from 2013-2017 and was the US Representative to the United Nations. In the Clinton administration, she served as the US Assistant Secretary of State for African Affairs. This year, she assisted the Mayor of Washington D.C.'s Reopen D.C. Program during the pandemic. She was a Rhodes Scholar at Oxford University and attended Stanford.
ADVISORS TO THE PRESIDENT
SENIOR ADVISOR TO THE PRESIDENT AND DIRECTOR OF THE WHITE HOUSE OFFICE OF PUBLIC ENGAGEMENT-Cedric Richmond
Cedric Richmond will be senior advisor to the President and head of the White House Office of public engagement after being the co-chair of the Biden Harris Campaign. Richmond was a United States representative for the second district of Louisiana. While a representative, he served on the Homeland Security Committee, the Judiciary Committee, and the Chairman of the Congressional Black Caucus. His work as a representative ensured that Louisiana is prepared for any possible natural disaster after the tragedy of Hurricane Katrina in 2005. Richman has spent his whole life in the city of New Orleans, attending Morehouse College and Tulane University School of Law.
SENIOR ADVISOR TO THE PRESIDENT-Mike Donilon
Mike Donilon will continue his work with President-Elect Biden as the Senior Advisor to the President. He previously served as the Chief Strategist of the Biden Campaign and has been a pollster for over four decades. He has also been an assistant professor at the University of Delaware and the managing director of the Biden Institute. Donilon is a graduate of Georgetown University and Georgetown University Law Center.
NATIONAL SECURITY ADVISOR-Jake Sullivan
After serving as the Deputy Chief of Staff to then Secretary of State Hillary Clinton, Jake Sullivan is the Biden Administration's National Security Advisor. In the last four years, Sullivan has taught at Yale, Dartmouth and the University of New Hampshire. He is a graduate of Yale University, Oxford, and Yale Law School.
LEGISLATIVE AFFAIRS-
DIRECTOR OF THE WHITE HOUSE OFFICE OF LEGISLATIVE AFFAIRS-Louisa Terrell
Louisa Terrell will hold the position of Director of the White House Office of Legislative Affairs in the Biden Administration. She has several years of experience on Capitol Hill, serving as Deputy Chief of Staff to then-Senator Biden and Chief of Staff for Senator Cory Booker. She is a graduate of Tufts University and Boston College School of Law.
DEPUTY DIRECTOR OF THE WHITE HOUSE OFFICE OF LEGISLATIVE AFFAIRS-Reema Dodin
Reema Dodin is the new Deputy Director of the White House Office of Legislative Affairs after serving as a volunteer on the Biden Harris transition team specializing in legislature. DEPUTY DIRECTOR OF THE WHITE HOUSE OFFICE OF LEGISLATIVE AFFAIRS-Shuwanza Goff
The next Deputy Director of the White House Office of Legislative Affairs is Shuwanza Goff She is a graduate of the University of Tennessee and America University.
After serving as the Vice President's Social Secretary for eight years, Carlos Elizondo will be the next White House Social Secretary. He is experienced in the position after managing several events for President-Elect Biden and Dr. Jill Biden during his time in the Obama Administration.
WHITE HOUSE COMMUNICATIONS DIRECTOR-Kate Bedingfield
After a successful campaign as the deputy manager, Kate Bedingfield will be serving as President Elect Biden's Communications Director. She has worked for Biden before as his Communications Director during the Obama Biden Administration. She also served as the Communications Director to Senator Jeanne Shaheen in her 2008 campaign. Bedingfield is a graduate of the University of Virginia.
WHITE HOUSE PRESS SECRETARY-Jen Psaki
Jen Psaki will be the next White House Press Secretary after currently overseeing the transition process for the President-Elect. She has worked on three different presidential campaigns including a position as the traveling secretary of the Obama Biden campaign. Before joining the Biden Harris campaign trail, she was the Vice President for Communications and Strategy at the Carnegie Endowment for International Peace and worked as a contributor to CNN. Ms. Psaki attended the College of William and Mary.
PRINCIPAL DEPUTY PRESS SECRETARY-Karine Jean-Pierre
Karine Jean-Pierre is the Biden Administration's Principal Deputy Press Secretary. She previously served as a senior advisor to Biden and Chief of Staff to Harris on the campaign trail. She has also worked at MSNBC as a political correspondent. She has served on a number of successful campaigns including Obama and Biden in 2008 and 2012. A native New Yorker, she is a graduate of Columbia University and was born in Martinique.
DEPUTY WHIITE HOUSE COMMUNICATIONS DIRECTOR-Pili Tobar
Pili Tobar is the new Deputy White House Communications Director. Previously, Tobar served as the Deputy Director of America's Voice, a group advocating for immigrants. She held the position as the Hispanic Media Director for Senate Minority Leader Chuck Schumer. A graduate of the University of Miami, she was raised in Florida and Guatemala.
VICE PRESIDENT'S CABINET-
COMMUNICATIONS DIRECTOR FOR THE VICE PRESIDENT-Ashley Etienne
Ashley Etienne will be serving as the Communications Director for Vice President-Elect Kamala Harris. She has previously served in the same position to Speaker of the House Nancy Pelosi. Representative Pelosi wished her former staff member well saying, "Her experience working on both sides of Pennsylvania Avenue and the immense respect she commands among both Members and staff will make her a powerful force in the Biden Harris Administration." She is a graduate of Sam Houston State University and Johns Hopkins University.
SENIOR ADVISOR AND CHIEF SPOKESPERSON FOR THE VICE PRESIDENT-Symone Sanders
Symone Sanders is a senior advisor and chief spokesperson for the Vice President. Previously, she held the position of the youngest ever Presidential Press Secretary on Senator Bernie Sanders' 2016 campaign. In between serving Sanders and Biden, she was a political correspondent for CNN and as the principal for 360 Group LLC, providing communications advice to clients.
THE FIRST LADY'S STAFF-
CHIEF OF STAFF TO DR. JILL BIDEN-Julissa Reynoso Pantaleon
Julissa Reynoso Pantaleon has been chosen to be the incoming First Lady's Chief of Staff. Reynoso Pantaleon was born in the Dominican Republic, immigrated to the United States at the age of 7, and grew up in the Bronx. She attended Harvard University, University of Cambridge, and Columbia Law School. During the Obama administration, she was the Ambassador to Uruguay and served as Deputy Assistant Secretary of State for the Western Hemisphere in the state department.
SENIOR ADVISOR TO DR. JILL BIDEN-Anthony Bernal
Anthony Bernal has been picked to beas the First Lady's Senior Advisor after serving as her deputy campaign manager and Chief of Staff on the campaign trail as well as chief of staff during her time as . He was her chief of staff as Second Lady in the Obama Administration. Bernaland he began his career in public service working in scheduling for President Bill Clinton and Vice President Al Gore. Born in Arizona, he attended Carleton College and the University of Texas at El Paso.
POLICY DIRECTOR TO DR. JILL BIDEN-Mala Adiga
Mala Adiga will be serving as the Policy Director to Dr. Jill Biden for the second time after serving as her senior advisor during the Obama Administration and on the campaign trail. She has previously worked as the Director for Higher Education and Military Families during the Obama Administration and had also spent several years in the state department as the Deputy Assistant Secretary of State for Academic Programs at the Bureau of Education and Cultural Affairs. She has also been the Director of Human Rights on the National Security Staff. She attended Grinnell College, the University of Minnesota School of Public Health, and the University of Chicago Law School.
COMMUNICATIONS DIRECTOR TO THE FIRST LADY-Elizabeth E. Alexander
After serving as a senior advisor on the campaign trail, Elizabeth E. Alexander will now be the new Communications Director to the First Lady Dr. Jill Biden. In the first four years of the Obama Biden Administration, Alexander was the Vice President's Press Secretary after serving as the Press Secretary for then-Senator Biden. She has served in a variety of positions in the communications field for Senator Chuck Schumer, the United Nations, the Democratic National Committee, and Congressman Adam Schiff. She is a graduate of both Texas A&M University and Georgetown University Law Center.
Afton is a sophomore at Mayfield and is the Crier's political reporter. Besides being a member of the newspaper, she is a member of the technical theater...
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