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Used-car sales: Tracking the good, the bad & the options
CARY, N.C. –
Based on auto industry analyses, a rough March for used-vehicle sales appears to have spilled over into April, and as PureCars says in its latest COVID-19 report, dealers are "facing obvious headwinds" in pre-owned.
But, some silver linings: the dive in used- and new-car sales appear to have hit its trough, according to Cox Automotive. And there are dealers who are realizing "some success" with strategies to shore up their used-car sales, as PureCars outlines in its report.
First outlining the challenges, PureCars said in the report, "Aggressive APR offers mean used payments can be higher than new, RO data suggests shoppers are fixing versus trading up or out, auction prices continue to fall, and wholesale markets have all but stopped operating as a way to dispose of depreciating used assets."
But there are some remedies dealers are finding that work. PureCars emphasizes that some used-vehicle shoppers "are sitting on the sidelines," so "aggressive" strategies in pre-owned might not be the best course at the moment.
"However, some dealers are gamblers and we've seen some success with the following tactics; low-funnel search awareness, social budget reallocations to move 'up funnel' to reach broader in-market shoppers to take advantage of falling CPM rates, overlay ORACLE dataset to hyper-target local in-market audiences, aggressively (re)pricing vehicles to drive intent, and piggy-backing on OEM CPO program benefits where available," PureCars said.
Here's how the numbers have shaken out recently in pre-owned.
Franchised dealers had a 24% drop in used-car retail sales the week ending April 5, according to J.D. Power Valuation Services, following 32% sequential and nearly 40% year-over-year declines in March.
Of the 25 states that provide vehicle sales data to Cross-Sell Interactive (which is part of Dominion Dealer Solutions), only one shown in a state-by-state comparison graph — North Dakota, which was up 10% — showed year-over-year growth in combined new- and used-vehicle sales in March.
The heaviest decline shown in Cross-Sell's data set was in Missouri, where combined new and used sales were down 52%. New York was next at 46%.
Several others, like Texas (down 28%), Michigan (27%), Indiana (25%) and Colorado (25%), had declines near 30%.
Overall, new- and used-vehicle sales fell 19.6% year-over-year, among states in Cross-Sell's data set.
In the 25 states that report data to Cross-Sell, there were 1.91 million used-vehicle sales for March, which was up 9.1% from the 1.75 million used sales in February.
However, the picture changes when looking at year-over-year comparisons.
Used-car sales in the 25 states were down 21.1% from the 2.42 million sold in March 2019.
Total used-vehicle sales in March fell 18.4% year-over-year, according to Cox Automotive, which estimated the used-car SAAR for the month at 32.0 million. It was 39.2 million in March 2019 and 39.8 million in February, Cox said.
For retail used (which Cox Automotive defines as sales from either franchised dealers or independent dealers, excluding private-party sales), the SAAR was approximately 17.3 million for March. It was 20.6 million a year ago and 21.2 million in February.
In addition to the 18% drop in total used sales for March, Cox Automotive also observed a 38% decline in new-car sales, with the downturn in both picking up as the month went along.
A bit of a silver lining though, as Cox Automotive said in an analysis: "The decline in sales bottomed last week, as we've seen seven consecutive days of improvement in year-over-year declines of both new and used through Wednesday, April 8."


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HomeTop NewsALERT: Assassin Hired to MURDER Major Trump Ally
ALERT: Assassin Hired to MURDER Major Trump Ally
August 14, 2017 Benjamin Welton Top News Comments Off on ALERT: Assassin Hired to MURDER Major Trump Ally
Yesterday, the Miami Herald released a shocking report. Although uncorroborated at this time, American law enforcement officials believe that a foreign politician sought to use Mexican "hitmen" against an American Senator.
According to the report, Venezuelan politician Diosdado Cabello considered ordering an assassination on Senator Marco Rubio (R-FL). The Herald claims that Rubio took this threat seriously enough that he began beefing up his security detail last month.
It appears that the conflict between Rubio and Carbello began when Rubio began accusing Carbello, a former official in the Venezuelan Army, of being a drug trafficker. Rubio has called Carbello the "Pablo Escobar of Venezuela." Carbello shot back on Twitter by dubbing Mr. Rubio "Narco Marco."
This war of words has an added dimension that could affect American foreign policy. It seems that Rubio is in the ear of President Trump when it comes to America's response to the ongoing political unrest in Venezuela. Rubio has called Venezuela a "personal priority" for President Trump.
It should also be noted that Rubio's accusations against Cabello and the United Socialist Party that he represents are backed by several federal agencies. The country's current vice president, Tarek El Aissami, is a known drug lord with ties to international drug traffickers.
American officials believe that besides abusing the country's sizable oil deposits, the socialist government of Nicolas Maduro relies on drug traffickers to keep his government afloat.
Despite the presence of armed "Colectivo" militiamen, and despite the constant threat of violence, Venezuelan citizens have been protesting President Maduro's regime for almost the entirety of 2017. In May, because of the ongoing political violence, Mr. Maduro's public support stood at an abysmal 26.8 percent. Another 68.9 percent believe that Maduro should leave office before the end of 2017.
Some members of the Venezuelan police and army have taken matters into their own hands. Pro-opposition police officers used a hijacked police helicopter to strafe Venezuela's Supreme Court and Interior Ministry. Also, before being put down, an army unit publicly mutinied against the Caracas government.
Due to all this unrest, President Trump told reporters last week that Washington has not ruled out a "military option" in Venezuela. Many fear that this call for an American invasion could bolster Maduro's flagging support. Colombian President Juan Manuel Santos has criticized Trump's invocation of American military action as the wrong way to approach the crisis.
Given how unpopular the United States is in most of Latin America, President Santos is probably right to worry that Trump's threats may actually help to keep Maduro in power.
Venezuela has been a hotbed of socialist corruption and violent political intimidation for decades. Do you believe that violent threats from Venezuela against US officials should be taken seriously?
It seems that Cabello's threat against Rubio was initially uncovered by American intelligence services, who then passed the sensitive information along to the senator. It is quite possible that the socialist government in Venezuela, which appears to be enjoying borrowed time, will lash out in destructive ways. President Trump has already declined one call from Maduro because of his country's suppression of the democratic rights of its citizens.
The best option going forward would be to continue to support the anti-regime protesters. They are the ones who must remove socialism from Venezuela. An American invasion would only help to unite Venezuelans against an outside aggressor.
BREAKING: NFL Player Slams America, Won't Stand For the National Anthem
BREAKING: NFL Star Drops Epic Truth Bomb On Kaepernick Supporters – It's Perfect

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Film Intuition: Review Database
By Jen Johans. Over 2,500 Film, Streaming, Blu-ray, DVD, Book, and Soundtrack Reviews. Part of https://www.filmintuition.com
Movie Review: I'm Your Woman (2020)
Swanky, immaculate, and impractical, "I'm Your Woman" opens in the luxe '70s Pennsylvania home afforded to Jean (Rachel Brosnahan) by her husband's life of crime. Also given to Jean within the first five minutes of the movie is a new baby that her man Eddie (Bill Heck) delivers like a jumpsuit, string of pearls, or new stereo that might have fallen off the back of a truck in his vicinity over the years.
The only difference between this and the typical swag that the veteran thief brings home is that this property is not only hot but it's also a living and breathing thing and as such, it looks immediately out of place in this cold, catalog ready environment.
Sensing his wife's hesitation, Eddie promises Jean that it's all worked out. "He's our baby," he explains but then changes his wording later on. He's "your baby," Eddie says, correcting himself in a line of dialogue that's as much an important distinction as it is an eerie piece of foreshadowing for the film.
You see, mere moments after he says this, Eddie disappears from Jean's life. And no, that's not a spoiler, it's merely the set-up for this engaging piece of storytelling from "Miss Stevens" and "Fast Color" director Julia Hart, who wrote the film along with her husband, producer Jordan Horowitz.
A clever reinvention of '70s cinematic crime fiction, in "I'm Your Woman," Jean gains a baby and loses a husband, the first when one arrives home unexpectedly and the second when the other does not. Thus, one man or – to be more precise – one "he" replaces the other in Jean's life and our leading lady goes from being the woman and the whole world for one to the woman and the whole world for another when Eddie fails to return home following a job gone disastrously wrong.
What went wrong on the job remains a mystery for the better part of the movie but it's only interesting from a tangential perspective because it happens offscreen. Serving not as the movie's climax the way that most heists are utilized in crime movies centered on male protagonists, "Woman" is instead concerned with how one man's actions and decisions affect the woman at its core and the baby she's left to protect.
"Something happened tonight," one of Eddie's partners tells her and, handing her a bag with two hundred grand in it and instructions to take the kid and go with a man named Cal (Arinzé Kene), we discern that that is all we need to know. Rather than stay with the crooks and either go to the mattresses or Sicily with the men eluding capture as we did in "The Godfather," Hart and Horowitz instead opt to follow Diane Keaton's Kay instead, or rather, their Kay in the form of Jean.
A light flutter of wind you initially ignore until it builds into a tornado that no one – not even the weatherman sees coming – Jean goes from a meek, decorative glass figurine living in her husband's dollhouse to a frazzled yet determined woman trying to find and hold onto any semblance of control she has in her new, now suddenly uncertain life. Who Jean is, as not Eddie's woman but her own (and now baby Harry's as well) is the crux of Hart's picture. And in a messy, initially submissive turn that's light-years away from her performance on "The Marvelous Mrs. Maisel," gifted producer-star Brosnahan is there, fully committed to exploring Jean's compelling evolution every step of the way, even when she occasionally but realistically goes backwards instead of forwards.
Thrillingly original and long overdue, particularly for women (like yours truly) who, long obsessed with '70s crime movies, didn't realize just how much they wanted and needed a film focused on the characters that far too often get left behind in traditional white-male-centric fare, one of the wisest decisions that Hart made was not to simply turn Michael into Missy Corleone. Avoiding the pitfalls of over-correction that we sometimes see in revisionist genre efforts where, rather than accurately reflect the true setting and history of the period of the movie, filmmakers will just make the hero a woman instead of a man, Hart opts to embrace rather than escape femininity here.
Jean isn't a crackerjack thief or a hitman, she is a crime syndicate wife who's never been on her own before and has no idea how to begin to move on, even temporarily, without a man. In addition to Harry, who is bringing out a new protective side in her, she gets a second man for a time in another figure that would ordinarily be a supporting character as well in the form of scene-stealer Kene's enigmatic Cal.
A Black former associate of Eddie's who he'd entrusted to look after Jean and the baby until either he, Cal, or Jean can figure something out, as a new stranger turned friend, he's at once a calming influence on both Jean and Harry and an armed guard you don't want to cross to everyone else. Yet Cal doesn't only serve to save Jean, even if this is his initial function at the beginning. As the film progresses, Jean finds that he might need to be saved right back. To do that, she'll need to join forces with another woman – Cal's woman, Terry (a masterful Marsha Stephanie Blake) – and one who, if Jean is being honest, is exactly the kind of woman she's always wanted to be herself.
Sharp, unfussy, character-driven filmmaking that has much more in common with the methodical, building block-based storytelling we so often saw in the 1970s as opposed to most modern movies where people frequently speak in expositional monologues, this is a film that tells us only what we need to know at any given moment. Respecting not only our intelligence but also the talents of the actors bringing their characters to life, Hart knows that we will come to better understand the people who populate her film in time. Therefore, she has no interest in giving us a cinematic version of Cliff's Notes to tell us what to think and refreshingly asks us to sit back, get lost in her world, and figure it all out for ourselves instead.
Suspenseful and unpredictable in the way that it leads us down one path only to veer wildly down another moments later, "Woman" leads to a few truly exciting action set-pieces over the course of its running time. A unique hybrid of '70s and modern filmmaking with a lead character who feels like a descendant of Gena Rowlands in "Gloria," "I'm Your Woman" is first and foremost a celebration of genre storytelling.
One of those mid-range adult thrillers that – as the old adage goes – they just don't make that much anymore since normally, it would be broken down into six half-stuffed episodes of lukewarm prestige television instead of a feature film, "I'm Your Woman" plays best to those who understand its cinematic lineage.
Wearing its influences like "The Friends of Eddie Coyle," "The Getaway," and other films from the era proudly in each frame, "I'm Your Woman" feels like a '70s movie released in 2020... if, you know, they actually made crime movies in the '70s that focused on what happens to the wives and girlfriends of a crook instead of just relegating them to the sidelines. The end result is a rousing film that plays like gangbusters. With first-rate production specs, including a dynamic soundtrack and crisp yet lived in cinematography from "Ingrid Goes West" DP Bryce Fortner, following this year's "Sound of Metal," "Small Axe" releases, "Vast of Night," and "Blow the Man Down," "I'm Your Woman" is proof that some of cinema's strongest new films are found on Amazon Prime.
Immediately pulling us into Jean's orbit, we watch as she goes from being defined by one man to asking herself just what kind of woman she wants to be both for herself and her child now that she's been left out in the cold. Finding strength she didn't know she had, in a film about people left behind, we meet a woman who at long last, knows her worth.
Text ©2020, Film Intuition, LLC; All Rights Reserved. https://www.filmintuition.com Unauthorized Reproduction or Publication Elsewhere is Strictly Prohibited and in violation of the Digital Millennium Copyright Act. Also, as an Amazon Associate, I earn from qualifying purchases made off my site through ad links. FTC Disclosure: Per standard professional practice, I may have received a review copy or screener link of this title to voluntarily decide to evaluate it for my readers, which had no impact whatsoever on whether or not it received a favorable or unfavorable critique. Cookies Notice: This site incorporates tools (including advertiser partners and widgets) that use cookies and may collect some personal information to display ads tailored to you etc. Please be advised that neither Film Intuition nor its site owner has any access to this data beyond general site statistics (geographical region etc.) as your privacy is our main concern.
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Weaver St. Market: Licensed for the Lawn!
Caught this young scofflaw just a short time after the private press conference announcing WSM's new policy of "licensing" lawn performers.
The, short notice, private press event, held by Ruffin Slater, general manager of the Weaver St. Market (WSM) co-op, and Nathan Milian, property manager of Carr Mill mall appears to have been short on answers, including how the new, by permission only "Live on the Lawn" program will work.
Local radio WCHL1360 covered the event, so, hopefully more details will be forthcoming. Until then, we'll have to scratch our heads about how the "limit of one performance per week per artist or group" will apply to free spirits like the young hoopers or even to the supposed reason for the new policy, dancing Bruce.
Nathan Milian underlined the graciousness of Carr Mill's owners in providing "an outlet for artists wishing to share their work with the general public, free of charge to both the artist and the public." Is that the same public that already supports Carr Mill's business with their hard-earned wages?
Milian, again spinning furiously, proclams this is "another way for the community to benefit from the lawn." No mention on how Carr Mill's tenants benefit from the community.
Applications for the new lawn license are not currently available (as of 4:30pm) but I've been told the office will have some tomorrow (Aug. 23rd).
The whole mess remains a cautionary tale for Chapel Hill as our Council rushes to turn over public-owned lands to private control. We need stronger requirements protecting open access to what will have been citizen-owned assets.


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Roads, parking and transport
Public rights of way
Temporary and Permanent Orders
Temporary path closures
Rights of way should always be open and available for the public to use but there are times when the Council will close them for short periods. PRoW must not be closed or restricted without our consent. Approved closures are deemed as necessary and as such consultations do not have to be undertaken.
The Council can temporarily close public rights of way under the Road Traffic Regulation Act 1984 if:
Works are proposed to be carried out on or near the right of way.
There is a potential danger to the public or serious damage to the right of way.
It is needed for maintenance works undertaken on behalf of the council.
Section 14 (1): Allows for public rights of way to be closed for 5 days and for 6 months. These requests must be submitted at least six weeks before the closure is required. If there is any doubt that work cannot be completed within five days, it is advisable that an order (valid for up to six months) is the best choice.
If a longer closure is required past the 6 month period, then an application has to be made to the Secretary of State for the Environment for an extension. This application must be made in good time before the initial closure period has expired and there will be an additional charge.
Section 14 (2): Allows for emergency closures of up to 21 days (routes must be inaccessible or dangerous for the public to use for an emergency closure)
We will require a written (email) request detailing what is to be closed, why, when and for how long.
The public rights of way officer will arrange an on-site meeting to discuss proposals and advise/agree on procedures and reinstatements.
Under the legislation we need to 'consider alternative routes' and we cannot obstruct pedestrian access to properties.
The public rights of way officer will arrange for the design, supply and installation of any associated signage and all costs will be funded by applicant.
Permanent diversions and closures ('stopped up')
It is recommended that you seek advice from the Public Rights of way Officer before proceeding with an application.
We deal with many applications for footpath diversions for a variety of reasons.
The main ones are outlined below:
Highways Act (HA) 1980 Diversion: Various sections of the HA 1980 allow us to consider making diversion orders on behalf of a landowner.
Town and Country Planning Act 1990: Section 257 allows rights of way to be diverted to enable development to take place. In other words, if a developer (for instance) has been given planning permission to build a housing estate, then any paths running over this land can be diverted to allow for the erection of the buildings.
We would require a developer to keep any changes to a minimum and to accommodate the path within the development. We work closely with developers and planners to ensure that the character of paths is not dramatically altered. For example, if land over which a rural cross field path is to be built on, we will expect developers to
Provide a wide, open path within the heart of the development and constructed to our standards.
Retain their priority over new estate roads with raised table or signalised crossings.
Any application for the extinguishment and/or diversion of footpaths and/or bridleways affected by development should be submitted along with the planning application.


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Q: Python Pandas: Passing Multiple Functions to agg() with Arguments I'm struggling to figure out how to combine two different syntaxes for pandas' dataframe.agg() function.  Take this simple data frame:
df = pd.DataFrame({'A': ['group1', 'group1', 'group2', 'group2', 'group3', 'group3'],
                   'B': [10, 12, 10, 25, 10, 12],
                   'C': [100, 102, 100, 250, 100, 102]})

>>> df
[output]
        A   B    C
0  group1  10  100
1  group1  12  102
2  group2  10  100
3  group2  25  250
4  group3  10  100
5  group3  12  102

I know you can send two functions to agg() and get a new data frame where each function is applied to each column:
df.groupby('A').agg([np.mean, np.std])

[output]
           B                C
        mean        std  mean         std
A
group1  11.0   1.414214   101    1.414214
group2  17.5  10.606602   175  106.066017
group3  11.0   1.414214   101    1.414214

And I know you can pass arguments to a single function:
df.groupby('A').agg(np.std, ddof=0)

[output]
          B   C
A
group1  1.0   1
group2  7.5  75
group3  1.0   1

But is there a way to pass multiple functions along with arguments for one or both of them?  I was hoping to find something like df.groupby('A').agg([np.mean, (np.std, ddof=0)]) in the docs, but so far no luck.  Any ideas?

A: Well, the docs on aggregate are in fact a bit lacking. There might be a way to handle this with the correct passing of arguments, and you could look into the source code of pandas for that (perhaps I will later).
However, you could easily do:
df.groupby('A').agg([np.mean, lambda x: np.std(x, ddof=0)])

And it would work just as well.

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Users of WhatsApp worldwide are complaining that the mobile messaging service is down.
The smartphone app uses symbols to inform users of how the transmission of their message is doing.
Worldwide, users are being shown the clock symbol after attempting to send a message, meaning that the message hasn't been sent to WhatsApp's servers.The website for the messaging app also appears to be down in what may be a domino effect.If a significant problem has affected WhatsApp's messaging servers causing the message issues, the resultant world-wide concern may have caused so much traffic to visit the website it has fallen down.The outage may be an embarrassment for WhatsApp's parent Facebook, which has this week announced record revenues from advertising.
Facebook declined to comment to Sky News when contacted.The Down Detector website's heat map showed reports were especially common in Europe, although complaints on social media came from people located worldwide.


Before you enter the Awards or sign up to be a Judge, you first need to set up an account or log in using your email and previously set password. Don't worry, this won't take too long and we only need a couple of pieces of information.
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With the rapid changes in the IT realm, both small and medium enterprises have upped their search for an IT service provider. Studies conducted two years ago found out that only 30 percent of organizations hired managed service providers, but as of now, the percentage has increased to 66 percent. Initially, this increase was attributed to companies getting more familiar with what's entailed in managed service. However, more business isn't only interested in what's involved in managed services, but the benefits presented by the services as well.
The authentication process is critical in securing operations of any network. This is because it ensures that only personnel who are authorized can get access to sensitive information. The expert will ensure the system is in place and always functioning.
It involves remotely managing and monitoring most items for the client that fall under his control. A lot of dedication and concentration are demanded in such a task, and only a skilled IT expert can be able to handle it.
It involves ensuring enough space for data storage and setting the required mechanism to prevent unauthorized access to data.
Having an understaffed IT department could lead to constant problems. Consequently, having an idle IT team will be a waste of a substantial amount of the company's revenue. With a service provider, you'll be assured of a great talent that is in line with the requirements of the company. Furthermore, you'll also incur lesser costs compared to the traditional in-house team.
Since managed service providers work on an agreed payment contract, budgeting turns out to be much easier and predictable. In addition, weekly or monthly schedules generate certainty in work delivery by the outsourced IT team.
Given the contract billing, it becomes possible to move your employee budget from capital to operational costs.
Technology is very dynamic, especially in the modern times. New critical technologies are emerging almost daily, and by outsourcing managed service providers, you can be assured of a team that's knowledgeable with what's currently trending.
You may lack complete details of what your business needs regarding IT, or be in doubt that you're either under-investing or over-investing. With a managed service provider, such worries will be a thing of the past. Providers adjust their services based on the requirements of your business.
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With the modern business trends, keeping an up-to-date IT infrastructure is one way of standing tall among your competitors. Make sure that you get a reliable IT service provider who will ensure that everything is in place and working towards your business goals.


The MP125/150 is a modular format medium-duty hydraulic strut combining the compressive strength of steel tube with the convenience of hydraulic actuation for length adjustment and pre-loading potential. Swivel end bearing units allow for various strutting configurations within an excavation, with or without waling beams.
Both MP125 and MP150 struts use nominally 500mm diameter tubular sections as the main structural member. At shorter spans, the hydraulic capacity limits the axial load and at longer spans, the potential for lateral buckling of the extension sections dictates overall axial capacity.
MP125 / 150 struts can be configured to work within an operating range of 3.6m to 20.0m without the need for intermediate support and are able to withstand working axial loads at shorter spans up to 125 / 150 tonnes respectively.
Equipment User Guide for the MP125 and MP150 hydraulic struts.


text:
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer
T. L. Taras, G. T. Wurz, M. W. DeGregorio
Ospemifene (FC-1271a) is a novel selective estrogen receptor modulator under development for osteoporosis prevention. In the present paper, we examine both the in vitro and in vivo effects of FC-1271a in breast cancer models. In vitro, the growth inhibitory effects of FC-1271a and its main metabolite are investigated in MCF-7 and MDA-MB-231 human breast cancer cells at doses ranging from 0.1 to 10 μM. Modulation of pS2 expression, an indicator of estrogen activity, was also examined in all experiments using reverse transcription-polymerase chain reaction. In vivo, the effects of treatment with 10, 25, 50, or 100 mg/kg FC-1271a on MCF-7 and MDA-MB-231 human tumor xenografts in athymic, ovariectomized mice were determined. For MCF-7 cells, FC-1271a and its main metabolite, toremifene VI (TOR VI) displayed anti-estrogenic effects in vitro as shown through growth inhibition and decreased expression of pS2. Treatment with FC-1271a in vivo inhibited MCF-7 tumor growth, compared with control (P ≤ 0.05). FC-1271a and TOR VI did not inhibit the growth of MDA-MB-231 cells in vitro, and no clear effects of FC-1271a treatment were seen on MDA-MB-231 tumor growth in vivo. In conclusion, FC-1271a appears to exert anti-estrogenic effects dependent on estrogen receptor positivity in vitro and in vivo on the growth of MCF-7 cells.
FC-1271a
SERMs
Fingerprint Dive into the research topics of 'In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer'. Together they form a unique fingerprint.
Ospemifene Medicine & Life Sciences
In Vitro Techniques Medicine & Life Sciences
Toremifene Medicine & Life Sciences
Tumors Chemical Compounds
Metabolites Chemical Compounds
Estrogens Medicine & Life Sciences
Taras, T. L., Wurz, G. T., & DeGregorio, M. W. (2001). In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. Journal of Steroid Biochemistry and Molecular Biology, 77(4-5), 271-279. https://doi.org/10.1016/S0960-0760(01)00066-8
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. / Taras, T. L.; Wurz, G. T.; DeGregorio, M. W.
In: Journal of Steroid Biochemistry and Molecular Biology, Vol. 77, No. 4-5, 2001, p. 271-279.
Taras, TL, Wurz, GT & DeGregorio, MW 2001, 'In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer', Journal of Steroid Biochemistry and Molecular Biology, vol. 77, no. 4-5, pp. 271-279. https://doi.org/10.1016/S0960-0760(01)00066-8
Taras TL, Wurz GT, DeGregorio MW. In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. Journal of Steroid Biochemistry and Molecular Biology. 2001;77(4-5):271-279. https://doi.org/10.1016/S0960-0760(01)00066-8
Taras, T. L. ; Wurz, G. T. ; DeGregorio, M. W. / In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. In: Journal of Steroid Biochemistry and Molecular Biology. 2001 ; Vol. 77, No. 4-5. pp. 271-279.
@article{854b2edae60543e6a4f0d12bd57eb80a,
title = "In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer",
abstract = "Ospemifene (FC-1271a) is a novel selective estrogen receptor modulator under development for osteoporosis prevention. In the present paper, we examine both the in vitro and in vivo effects of FC-1271a in breast cancer models. In vitro, the growth inhibitory effects of FC-1271a and its main metabolite are investigated in MCF-7 and MDA-MB-231 human breast cancer cells at doses ranging from 0.1 to 10 μM. Modulation of pS2 expression, an indicator of estrogen activity, was also examined in all experiments using reverse transcription-polymerase chain reaction. In vivo, the effects of treatment with 10, 25, 50, or 100 mg/kg FC-1271a on MCF-7 and MDA-MB-231 human tumor xenografts in athymic, ovariectomized mice were determined. For MCF-7 cells, FC-1271a and its main metabolite, toremifene VI (TOR VI) displayed anti-estrogenic effects in vitro as shown through growth inhibition and decreased expression of pS2. Treatment with FC-1271a in vivo inhibited MCF-7 tumor growth, compared with control (P ≤ 0.05). FC-1271a and TOR VI did not inhibit the growth of MDA-MB-231 cells in vitro, and no clear effects of FC-1271a treatment were seen on MDA-MB-231 tumor growth in vivo. In conclusion, FC-1271a appears to exert anti-estrogenic effects dependent on estrogen receptor positivity in vitro and in vivo on the growth of MCF-7 cells.",
keywords = "FC-1271a, MCF-7, MDA-MB-231, Metabolites, Ospemifene, pS2, SERMs",
author = "Taras, {T. L.} and Wurz, {G. T.} and DeGregorio, {M. W.}",
journal = "Journal of Steroid Biochemistry and Molecular Biology",
T1 - In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer
AU - Taras, T. L.
AU - Wurz, G. T.
AU - DeGregorio, M. W.
N2 - Ospemifene (FC-1271a) is a novel selective estrogen receptor modulator under development for osteoporosis prevention. In the present paper, we examine both the in vitro and in vivo effects of FC-1271a in breast cancer models. In vitro, the growth inhibitory effects of FC-1271a and its main metabolite are investigated in MCF-7 and MDA-MB-231 human breast cancer cells at doses ranging from 0.1 to 10 μM. Modulation of pS2 expression, an indicator of estrogen activity, was also examined in all experiments using reverse transcription-polymerase chain reaction. In vivo, the effects of treatment with 10, 25, 50, or 100 mg/kg FC-1271a on MCF-7 and MDA-MB-231 human tumor xenografts in athymic, ovariectomized mice were determined. For MCF-7 cells, FC-1271a and its main metabolite, toremifene VI (TOR VI) displayed anti-estrogenic effects in vitro as shown through growth inhibition and decreased expression of pS2. Treatment with FC-1271a in vivo inhibited MCF-7 tumor growth, compared with control (P ≤ 0.05). FC-1271a and TOR VI did not inhibit the growth of MDA-MB-231 cells in vitro, and no clear effects of FC-1271a treatment were seen on MDA-MB-231 tumor growth in vivo. In conclusion, FC-1271a appears to exert anti-estrogenic effects dependent on estrogen receptor positivity in vitro and in vivo on the growth of MCF-7 cells.
AB - Ospemifene (FC-1271a) is a novel selective estrogen receptor modulator under development for osteoporosis prevention. In the present paper, we examine both the in vitro and in vivo effects of FC-1271a in breast cancer models. In vitro, the growth inhibitory effects of FC-1271a and its main metabolite are investigated in MCF-7 and MDA-MB-231 human breast cancer cells at doses ranging from 0.1 to 10 μM. Modulation of pS2 expression, an indicator of estrogen activity, was also examined in all experiments using reverse transcription-polymerase chain reaction. In vivo, the effects of treatment with 10, 25, 50, or 100 mg/kg FC-1271a on MCF-7 and MDA-MB-231 human tumor xenografts in athymic, ovariectomized mice were determined. For MCF-7 cells, FC-1271a and its main metabolite, toremifene VI (TOR VI) displayed anti-estrogenic effects in vitro as shown through growth inhibition and decreased expression of pS2. Treatment with FC-1271a in vivo inhibited MCF-7 tumor growth, compared with control (P ≤ 0.05). FC-1271a and TOR VI did not inhibit the growth of MDA-MB-231 cells in vitro, and no clear effects of FC-1271a treatment were seen on MDA-MB-231 tumor growth in vivo. In conclusion, FC-1271a appears to exert anti-estrogenic effects dependent on estrogen receptor positivity in vitro and in vivo on the growth of MCF-7 cells.
KW - FC-1271a
KW - MCF-7
KW - MDA-MB-231
KW - Metabolites
KW - Ospemifene
KW - pS2
KW - SERMs
JO - Journal of Steroid Biochemistry and Molecular Biology
JF - Journal of Steroid Biochemistry and Molecular Biology


text:
Daily temperature extremes over Egypt: Spatial patterns, temporal trends, and driving forces
Ahmed M. El Kenawy*, Juan I. Lopez-Moreno, Matthew F. McCabe, S. M. Robaa, Fernando Domínguez-Castro, Marina Peña-Gallardo, Ricardo M. Trigo, Mohamed E. Hereher, Talal Al-Awadhi, Sergio M. Vicente-Serrano
Spatial and temporal changes of daily temperature extremes are investigated over Egypt using a standard set of 23 indices. Our analysis uses a database consisting of complete, high quality and homogenous daily maximum and minimum air temperature records at 40 stations, spanning the period from 1983 to 2015. The trends were assessed using a least squares regression model, and its significance was determined by means of the modified Mann-Kendall test (p < .05). Results demonstrate that the frequency, intensity, and persistence of warm extremes increased significantly over the study period, with a clear spatial gradient from southeast to northwest. The strongest warming was more evident in coastal areas along the Red Sea and the Sinai Peninsula. In contrast, changes in cold extremes were mostly non-significant, with a divergence in the trends (i.e. positive and negative). Changes in variability indices such as the diurnal temperature range (DTR) were more consistent with those of warm extremes than with cold extremes. Our results also demonstrate that maximum air temperature witnessed stronger warming than minimum air temperature, leading to a dramatic increase in DTR, especially in the last decade. This study also points at the possible physical mechanisms responsible for the detectable changes in temperature extremes using sea level pressure and geopotential field data. Results indicate that anomalous warm events over Egypt are directly related to easterly winds that bring warm and dry air from the Arabian Peninsula and the Iranian Plateau, accompanied by strong ridges over the eastern Mediterranean and an intensification of the Asian monsoon lows. On the other hand, the occurrence of anomalous cold events can be linked to the east-west pressure gradient between the North Atlantic Highs and the Siberian and Persian Troughs, which enhances a northerly and northwesterly cold advection from Northern Europe to Egypt. This situation is also combined with a subsidence of cooler air from the mid to low troposphere. Overall, the observed changes in warm extremes could have profound ecological, hydrological and socioeconomic impacts, especially for crop production, water resources management and energy consumption. As such, improving the insight and understanding of such changes is of considerable importance to provide guidance to policymakers and stakeholders to develop more appropriate adaptation strategies.
https://doi.org/10.1016/j.atmosres.2019.04.030
Atmospheric configurations
Daily air temperature
10.1016/j.atmosres.2019.04.030
Dive into the research topics of 'Daily temperature extremes over Egypt: Spatial patterns, temporal trends, and driving forces'. Together they form a unique fingerprint.
Temperature Range Engineering 100%
Advection Engineering 49%
Coastal Area Engineering 49%
Least Square Engineering 49%
Square Regression Engineering 49%
Pressure Gradient Engineering 49%
Field Data Engineering 49%
Stakeholder Engineering 49%
El Kenawy, A. M., Lopez-Moreno, J. I., McCabe, M. F., Robaa, S. M., Domínguez-Castro, F., Peña-Gallardo, M., Trigo, R. M., Hereher, M. E., Al-Awadhi, T., & Vicente-Serrano, S. M. (2019). Daily temperature extremes over Egypt: Spatial patterns, temporal trends, and driving forces. Atmospheric Research, 226, 219-239. https://doi.org/10.1016/j.atmosres.2019.04.030
Daily temperature extremes over Egypt : Spatial patterns, temporal trends, and driving forces. / El Kenawy, Ahmed M.; Lopez-Moreno, Juan I.; McCabe, Matthew F. et al.
In: Atmospheric Research, Vol. 226, 15.09.2019, p. 219-239.
El Kenawy, AM, Lopez-Moreno, JI, McCabe, MF, Robaa, SM, Domínguez-Castro, F, Peña-Gallardo, M, Trigo, RM, Hereher, ME, Al-Awadhi, T & Vicente-Serrano, SM 2019, 'Daily temperature extremes over Egypt: Spatial patterns, temporal trends, and driving forces', Atmospheric Research, vol. 226, pp. 219-239. https://doi.org/10.1016/j.atmosres.2019.04.030
El Kenawy AM, Lopez-Moreno JI, McCabe MF, Robaa SM, Domínguez-Castro F, Peña-Gallardo M et al. Daily temperature extremes over Egypt: Spatial patterns, temporal trends, and driving forces. Atmospheric Research. 2019 Sep 15;226:219-239. doi: 10.1016/j.atmosres.2019.04.030
El Kenawy, Ahmed M. ; Lopez-Moreno, Juan I. ; McCabe, Matthew F. et al. / Daily temperature extremes over Egypt : Spatial patterns, temporal trends, and driving forces. In: Atmospheric Research. 2019 ; Vol. 226. pp. 219-239.
@article{b5a4ac174f974aa6b6e9698dc0a13951,
title = "Daily temperature extremes over Egypt: Spatial patterns, temporal trends, and driving forces",
abstract = "Spatial and temporal changes of daily temperature extremes are investigated over Egypt using a standard set of 23 indices. Our analysis uses a database consisting of complete, high quality and homogenous daily maximum and minimum air temperature records at 40 stations, spanning the period from 1983 to 2015. The trends were assessed using a least squares regression model, and its significance was determined by means of the modified Mann-Kendall test (p < .05). Results demonstrate that the frequency, intensity, and persistence of warm extremes increased significantly over the study period, with a clear spatial gradient from southeast to northwest. The strongest warming was more evident in coastal areas along the Red Sea and the Sinai Peninsula. In contrast, changes in cold extremes were mostly non-significant, with a divergence in the trends (i.e. positive and negative). Changes in variability indices such as the diurnal temperature range (DTR) were more consistent with those of warm extremes than with cold extremes. Our results also demonstrate that maximum air temperature witnessed stronger warming than minimum air temperature, leading to a dramatic increase in DTR, especially in the last decade. This study also points at the possible physical mechanisms responsible for the detectable changes in temperature extremes using sea level pressure and geopotential field data. Results indicate that anomalous warm events over Egypt are directly related to easterly winds that bring warm and dry air from the Arabian Peninsula and the Iranian Plateau, accompanied by strong ridges over the eastern Mediterranean and an intensification of the Asian monsoon lows. On the other hand, the occurrence of anomalous cold events can be linked to the east-west pressure gradient between the North Atlantic Highs and the Siberian and Persian Troughs, which enhances a northerly and northwesterly cold advection from Northern Europe to Egypt. This situation is also combined with a subsidence of cooler air from the mid to low troposphere. Overall, the observed changes in warm extremes could have profound ecological, hydrological and socioeconomic impacts, especially for crop production, water resources management and energy consumption. As such, improving the insight and understanding of such changes is of considerable importance to provide guidance to policymakers and stakeholders to develop more appropriate adaptation strategies.",
keywords = "Atmospheric configurations, Daily air temperature, Egypt, Extremes, Trend analysis",
author = "{El Kenawy}, {Ahmed M.} and Lopez-Moreno, {Juan I.} and McCabe, {Matthew F.} and Robaa, {S. M.} and Fernando Dom{\'i}nguez-Castro and Marina Pe{\~n}a-Gallardo and Trigo, {Ricardo M.} and Hereher, {Mohamed E.} and Talal Al-Awadhi and Vicente-Serrano, {Sergio M.}",
note = "Funding Information: The authors are grateful to the Egyptian Meteorological Authority for providing daily rainfall data used in this study. This work was supported by the research project PCIN-2015-220 and CGL2014-52135-C03-01 financed by the Spanish Commission of Science and Technology and the European Regional Development Fund (FEDER), IMDROFLOOD financed by the Water Works 2014 co-funded call of the European Commission and INDECIS , which is part of the European Research Area for Climate Services ( ERA4CS ), an ERA-NET initiated by JPI Climate, and funded by the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS), the German Aerospace Centre (DLR), the Austrian Federal Ministry of Science, Research and Economy (BMWFW) , the Innovation Fund Denmark (IFD), the Spanish Ministerio de Econom{\'i}a (MINECO), the French National Research Agency (ANR) with co-funding by the European Union (Grant 690462 ). AK is supported by Juan de la Cierva Fellowship . MFM was funded by the King Abdullah University of Science and Technology (KAUST). This work was also supported by the Sultan Qaboos University, Muscat, the Sultanate of Oman, as a part of the HM Trust Fund ( Strategic Project # SR/ART/GEOG/17/01 ). Finally, we would like to thanks you for your great time and effort. Publisher Copyright: {\textcopyright} 2019 Elsevier B.V.",
doi = "10.1016/j.atmosres.2019.04.030",
journal = "Atmospheric Research",
T1 - Daily temperature extremes over Egypt
T2 - Spatial patterns, temporal trends, and driving forces
AU - El Kenawy, Ahmed M.
AU - Lopez-Moreno, Juan I.
AU - McCabe, Matthew F.
AU - Robaa, S. M.
AU - Domínguez-Castro, Fernando
AU - Peña-Gallardo, Marina
AU - Trigo, Ricardo M.
AU - Hereher, Mohamed E.
AU - Al-Awadhi, Talal
AU - Vicente-Serrano, Sergio M.
N1 - Funding Information: The authors are grateful to the Egyptian Meteorological Authority for providing daily rainfall data used in this study. This work was supported by the research project PCIN-2015-220 and CGL2014-52135-C03-01 financed by the Spanish Commission of Science and Technology and the European Regional Development Fund (FEDER), IMDROFLOOD financed by the Water Works 2014 co-funded call of the European Commission and INDECIS , which is part of the European Research Area for Climate Services ( ERA4CS ), an ERA-NET initiated by JPI Climate, and funded by the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS), the German Aerospace Centre (DLR), the Austrian Federal Ministry of Science, Research and Economy (BMWFW) , the Innovation Fund Denmark (IFD), the Spanish Ministerio de Economía (MINECO), the French National Research Agency (ANR) with co-funding by the European Union (Grant 690462 ). AK is supported by Juan de la Cierva Fellowship . MFM was funded by the King Abdullah University of Science and Technology (KAUST). This work was also supported by the Sultan Qaboos University, Muscat, the Sultanate of Oman, as a part of the HM Trust Fund ( Strategic Project # SR/ART/GEOG/17/01 ). Finally, we would like to thanks you for your great time and effort. Publisher Copyright: © 2019 Elsevier B.V.
N2 - Spatial and temporal changes of daily temperature extremes are investigated over Egypt using a standard set of 23 indices. Our analysis uses a database consisting of complete, high quality and homogenous daily maximum and minimum air temperature records at 40 stations, spanning the period from 1983 to 2015. The trends were assessed using a least squares regression model, and its significance was determined by means of the modified Mann-Kendall test (p < .05). Results demonstrate that the frequency, intensity, and persistence of warm extremes increased significantly over the study period, with a clear spatial gradient from southeast to northwest. The strongest warming was more evident in coastal areas along the Red Sea and the Sinai Peninsula. In contrast, changes in cold extremes were mostly non-significant, with a divergence in the trends (i.e. positive and negative). Changes in variability indices such as the diurnal temperature range (DTR) were more consistent with those of warm extremes than with cold extremes. Our results also demonstrate that maximum air temperature witnessed stronger warming than minimum air temperature, leading to a dramatic increase in DTR, especially in the last decade. This study also points at the possible physical mechanisms responsible for the detectable changes in temperature extremes using sea level pressure and geopotential field data. Results indicate that anomalous warm events over Egypt are directly related to easterly winds that bring warm and dry air from the Arabian Peninsula and the Iranian Plateau, accompanied by strong ridges over the eastern Mediterranean and an intensification of the Asian monsoon lows. On the other hand, the occurrence of anomalous cold events can be linked to the east-west pressure gradient between the North Atlantic Highs and the Siberian and Persian Troughs, which enhances a northerly and northwesterly cold advection from Northern Europe to Egypt. This situation is also combined with a subsidence of cooler air from the mid to low troposphere. Overall, the observed changes in warm extremes could have profound ecological, hydrological and socioeconomic impacts, especially for crop production, water resources management and energy consumption. As such, improving the insight and understanding of such changes is of considerable importance to provide guidance to policymakers and stakeholders to develop more appropriate adaptation strategies.
AB - Spatial and temporal changes of daily temperature extremes are investigated over Egypt using a standard set of 23 indices. Our analysis uses a database consisting of complete, high quality and homogenous daily maximum and minimum air temperature records at 40 stations, spanning the period from 1983 to 2015. The trends were assessed using a least squares regression model, and its significance was determined by means of the modified Mann-Kendall test (p < .05). Results demonstrate that the frequency, intensity, and persistence of warm extremes increased significantly over the study period, with a clear spatial gradient from southeast to northwest. The strongest warming was more evident in coastal areas along the Red Sea and the Sinai Peninsula. In contrast, changes in cold extremes were mostly non-significant, with a divergence in the trends (i.e. positive and negative). Changes in variability indices such as the diurnal temperature range (DTR) were more consistent with those of warm extremes than with cold extremes. Our results also demonstrate that maximum air temperature witnessed stronger warming than minimum air temperature, leading to a dramatic increase in DTR, especially in the last decade. This study also points at the possible physical mechanisms responsible for the detectable changes in temperature extremes using sea level pressure and geopotential field data. Results indicate that anomalous warm events over Egypt are directly related to easterly winds that bring warm and dry air from the Arabian Peninsula and the Iranian Plateau, accompanied by strong ridges over the eastern Mediterranean and an intensification of the Asian monsoon lows. On the other hand, the occurrence of anomalous cold events can be linked to the east-west pressure gradient between the North Atlantic Highs and the Siberian and Persian Troughs, which enhances a northerly and northwesterly cold advection from Northern Europe to Egypt. This situation is also combined with a subsidence of cooler air from the mid to low troposphere. Overall, the observed changes in warm extremes could have profound ecological, hydrological and socioeconomic impacts, especially for crop production, water resources management and energy consumption. As such, improving the insight and understanding of such changes is of considerable importance to provide guidance to policymakers and stakeholders to develop more appropriate adaptation strategies.
KW - Atmospheric configurations
KW - Daily air temperature
KW - Egypt
KW - Extremes
KW - Trend analysis
U2 - 10.1016/j.atmosres.2019.04.030
DO - 10.1016/j.atmosres.2019.04.030
JO - Atmospheric Research
JF - Atmospheric Research


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Thou shalt not wear a black suit. Except to funerals. Or if you're a waiter.
This is a fundamental commandment of received menswear wisdom, and one I've lived by for over two decades of deliberate dressing. It never seemed arbitrary to me, but rather a logical corollary to a traditional aesthetic of patterned worsteds, melanged flannels, and colorful tweeds. Black was flat, harsh, dull, and draining — vociferously condemned by sartorial smartypants like myself as a mass-produced uniform of indifferent labor and fashionable consumption.
As is so often the case with inflexible dictates, however, dogma belies insecurity, suggests doubt. After all, black is almost universally embraced by women as flattering, and since at least the 1950s has dispelled any lingering Victorian gloominess with a crisp air of minimalist sophistication. It has long been the favored attire of fashionistas around the runway, Hollywood on the red carpet, Beautiful People at the velvet rope. It is, in a word, chic.
It's a richly nuanced term. Perhaps best defined as "fashionably refined with a soupçon of Francophone attitude," chic is a somewhat suspect virtue for many male dressers precisely because we tend to eschew fashion. This aversion usually takes the benevolent form of avoiding designer trends, fetishizing what we hope is timelessness, and methodically assembling fine classic wardrobes like so many blue chip stock portfolios. Sometimes, however, this anti-fashion attitude can carry a sharper edge, becoming a curmudgeonly, even reactionary rejection of stylishness itself. Who are you trying to impress in that black suit?
I picked up my black suit a few years ago. A secondhand wool and mohair three-button with a svelte cut so flattering that I suspended my no-black policy, rather morbidly justifying it as a funeral suit that would inevitably come in handy. It hung unworn in my closet for years (thankfully!), but I found myself flirting with it more and more after coming aboard at the Custom Shop, where I noted the frequency and aplomb with which Alan himself pulls off inky black attire. I'm too deeply ingrained with the aesthetic rationale of anti-blackers for it to ever become a regular look for me, but as I've come to appreciate the positive virtues of the shade — its liquid sleekness, its streetwise modernity, its sexiness — my black suit has entered rotation.
Alan approves. So does my wife. A little chic can shake things up for the better, like a dash of Audrey for the most Astaire among us.


Ia Dübois' research initially focused on issues of ethnic identity in Sweden and in Swedish literature. Inspired by her interest in interdisciplinary approaches to her research, and by a course she created a few years ago, Dr. Dübois turned her research from Scandinavian literature for a while to focus on a comparative study of sexuality in Scandinavia with the intent to find out if, and how, the Scandinavian countries differ in their perceptions of sexuality in society. More specifically, what made Sweden so progressive and liberal after the welfare state was established in 1933?
As Dübois soon found more differences between the Nordic countires than she expected, the initial phase of her research focused on socio-political issues, particularly on legislative actions with regards to human sexuality. While issues like homosexuality, prostitution and trafficking of women and children are debated globally today, each Scandinavian country has its own interpretation of how their society should handle these issues.
Dr. Dübois spent the Fall Quarter 2006 at Linköping University in Sweden, where she was a Jonsson Family Scholar.
Ia Dübois. "Lars Gustafsson." Twentieth-Century Swedish Writers, Dictionary of Literary Biography. Vol 257. Detroit: Gale Group, 2002. 115-130.
Ia Dübois. "Katarina Frostenson." Twentieth-Century Swedish Writers, Dictionary of Literary Biography. Vol 257. Detroit: Gale Group, 2002. 90-97.
Ia Dübois. Katherine Hanson, eds. Echo: Scandinavian Stories About Girls. Seattle: Women in Translation, 2000.
Ia Dübois. "In Search of an Identity: The Heroic Quest in Lars Gustfsson's Fiction." Scandinavian Studies. 1995.
Ia Dübois. Article on Katarina Frostenson (to be titled). Female Voices of the North. Ed. by Inger Olsen and Sven H. Rossel. Vienna: Editon Praesens. In progress.
Ia Dübois. Book on Sexuality in Scandinavia. In progress.
Warburton, Timothy. "Queered Bodies That Matter: Non-normative Bodies in Selected Paintings by Odd Nerdrum and 'Ecce Homo' by Elisabeth Ohlson Wallin." MA Thesis. University of Washington, 2011.


Swarn Bhasma, Prawal Pishti, Sudha Hing (Ferula asafetida), Safed Mirch (Piper nigrum), Kasturi (Curcuma aromatic), Nag Bhasma, Bang Bhasma, Abhrak Bhasma and other prominent herbs.
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Basic Ayurveda Swarna Malini Vasant Ras is an immunity enhancer and antibiotic medicine used for treatment of chronic fevers, general fatigue, weakness after fever or any wayward disease such as tuberculosis or heart diseases.


Building on Jesus' teachings in Mark's Gospel (Mark 8:27-38; Mark 9:30-37; 42-50; and Mark 10:32-45), Rev. Jim explained that being "In Christ" means that we must die to our so-called status and agenda and become like servants to all.
Regardless of denominational or tradition affiliation, what's important is not if I am baptist, methodist, pentecostal, presbyterian, etc.
In such a self-centered and selfish society a lesson about selflessness falls on deaf ears more times that it should.
Probably because we just don't get it!
Jim's sermon brings hope to a self-centered society. he explained that dying to Christ means "denying self, losing self, and forfeiting self;" but, not in a gnostic sort of way as in self-torture.
Indeed, we must take care of ourselves; but not for ourselves.
When Christ calls a man, he bids him come and die. It may be a death like that of the first disciples who had to leave home and work to follow him, or it may be a death like Luther's, who had to leave the monastery and go out into the world. But it is the same death every time—death in Jesus Christ, the death of the old man at his call.
We cannot truly serve God and His work in the world until we are truly OUT of self and IN Christ.
Let's ponder this question: "Am I into my self? Or, am I into Christ? If I am into myself, I serve myself. If I am into Christ, I serve Christ. This means that I am willing to deny myself for Christ's sake, lose myself in Christ, and forfeit my will to serve Christ and Christ's agenda in the world.
What eternal joy and great privilege to serve the Lord!


It is obvious that telecom pricing is in a declining state. Credit VoIP and wireless carriers for this. Many analysts say consolidation is necessary in a market with declining pricing. Motley Fool has an interesting article about why the SBC/AT&T merger doesn't make sense. The author argues that two companies that aren't doing great shouldn't combine as they will make even less money. There may be some logic here.
The flipside to this argument is that CallVantage could be the white knight of AT&T and by investing even more into VoIP, AT&T can more quickly become a global provider of VoIP and possible be the largest VoIP provider worldwide. Are there inherent advantages to being an ILEC as well? Perhaps. Imagine the kind of deals you could make with other service providers around the world... You give me favorable rates terminating on your network and will do the same.
Are there legal issues here? Possibly but there seem to be inherent advantages in being able to terminate calls in your own area which in SBC's case is the east and west coasts. Will Vonage get a fair shake selling into SBC/AT&T territories? We will have to wait and see.
In summary, perhaps the article gets it wrong. There are tremendous synergies in being able to sell broadband around the US and also VoIP with a globally recognized brand. We are talking about what could become a telecom mega-giant. Will the government allow it? Possibly... We will see. But from an investment perspective, if VoIP keeps growing worldwide at such an incredible pace, having the AT&T CallVantage name to sell isn't such a bad proposition.