text:
US8529455B2 - Systems and methods for estimating the size and position of a medical device to be applied within a patient - Google Patents
Systems and methods for estimating the size and position of a medical device to be applied within a patient Download PDF
graphical representation
Michael D. Rold
Shashidhar Sathyanarayana
Tat-Jin Teo
Boston Scientific Scimed Inc
2011-09-07 Application filed by Boston Scientific Scimed Inc filed Critical Boston Scientific Scimed Inc
A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
A61B8/46—Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
A61B8/461—Displaying means of special interest
A61B8/463—Displaying means of special interest characterised by displaying multiple images or images and diagnostic data on one display
A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
The field of the invention relates to medical imaging systems, and more particularly to systems and methods for estimating the size and position of a stent or other medical device within a patient. In one embodiment, a medical imaging system includes an elongated tubular member having distal and proximal ends, configured to be inserted into a vessel of a patient, an imaging device coupled to the distal end of the elongated tubular member, and a console electrically coupled to the imaging device, wherein the console includes a computer-usable medium, electrically coupled to the imaging device, having a sequence of instructions which, when executed by a processor, causes said processor to execute a process including generating an image of the vessel, and overlay one or more shapes onto the image age to provide a visual approximation of the size and position of a medical device to be applied within the patient.
This patent application is a continuation of U.S. patent application Ser. No. 11/865,699 filed on Oct. 1, 2007, which is a continuation-in-part of U.S. Pat. No. 7,892,177 issued Feb. 22, 2011, all of which are incorporated herein by reference.
The field of the invention relates to medical imaging systems, and more particularly to systems and methods for estimating the size and position of a medical device to be applied within a patient.
Intraluminal, intracavity, intravascular, and intracardiac treatments and diagnosis of medical conditions utilizing minimally invasive procedures are effective tools in many areas of medical practice. These procedures are typically performed using imaging and treatment catheters that are inserted percutaneously into the body and into an accessible vessel of the vascular system at a site remote from the vessel or organ to be diagnosed and/or treated, such as the femoral artery. The catheter is then advanced through the vessels of the vascular system to the region of the body to be treated. The catheter may be equipped with an imaging device, typically an ultrasound imaging device, which is used to locate and diagnose a diseased portion of the body, such as a stenosed region of an artery. For example, U.S. Pat. No. 5,368,035, issued to Hamm et al., the disclosure of which is incorporated herein by reference, describes a catheter having an intravascular ultrasound imaging transducer.
FIG. 1 shows an example of an imaging transducer assembly 1 known in the art. The imaging transducer 1 is typically within the lumen 10 of a guidewire (partially shown), having an outer tubular wall member 5. To obtain an image of a blood vessel, the imaging transducer assembly 1 may be inserted into the vessel. The transducer assembly 1 may then rotate while simultaneously emitting energy pulses, e.g., ultrasound waves, at portions of the vessel from within the vessel and receiving echo or reflected signals.
Turning to FIG. 2, it is known in the art that an imaging console 20 having a display screen, a processor and associated graphics hardware (not shown) may be coupled with the imaging transducer assembly 1 to form a medical imaging system 30. The imaging console 20 processes the received echo signals from the imaging transducer assembly 1 and forms images of the area being imaged. To form the images, the imaging console 20 draws multiple lines, known as "radial lines", (not shown) on the display screen that each correspond to an angular position of the transducer assembly 1. The processor of the imaging console 20 assigns brightness values to pixels of the lines based on magnitude levels of the echo signals received from the transducer assembly 1 at the angular positions corresponding to the lines. A drawing that includes a large number of these radial lines results in an image such as an intravascular ultrasound (IVUS) image (not shown).
It is further known in the art to continually capture frames of IVUS images while gradually withdrawing the transducer or catheter within a vessel. The resulting stack of frames may be stored and manipulated by the processor, and from these frames, a longitudinal image of the vessel may be generated. In other words, a visualization of the vessel in a plane containing the long axis of the vessel may be rendered, which allows the clinician to assess blockage at different locations along the length of the vessel. For example, U.S. Pat. No. 5,830,145, issued to Tenhoff, the disclosure of which is incorporated herein by reference, describes a system and method for generating longitudinal images of a region of a blood vessel.
The resulting longitudinal image may be used to diagnose abnormalities, such as blockage, within the vessel. A typical treatment known in the art for such abnormalities is the use of one or more stents in the region(s) of interest. Often times, determining the proper size (length and diameter) and position of the stent(s) to be applied within the patient is a "trial and error" type process, which may increase procedure time and risk to the patient. Accordingly, an improved system and method for delivering one or more stents would be desirable.
In one embodiment, a medical imaging system includes an elongated tubular member having distal and proximal ends, configured to be inserted into a vessel of a patient, an imaging device coupled to the distal end of the elongated tubular member and configured to emit one or more energy pulses and receive one or more echo signals, and a console electrically coupled to the imaging device, wherein the console includes a computer-usable medium, electrically coupled to the imaging device, having a sequence of instructions which, when executed by a processor, causes said processor to execute a process including generating an image of the vessel, and providing a graphical representation of a stent or other medical device to be overlaid onto the image. In an exemplary embodiment, different shapes, e.g., a rectangle, may be overlaid onto the image to provide a visual approximation of the size and position of a medical device to be applied within the patient.
Other systems, methods, features and advantages of the invention will be or will become apparent to one with skill in the art upon examination of the following figures and detailed description. It is intended that all such additional systems, methods, features and advantages be included within this description, be within the scope of the invention, and be protected by the accompanying claims.
In order to better appreciate how the above-recited and other advantages and objects of the inventions are obtained, a more particular description of the embodiments briefly described above will be rendered by reference to specific embodiments thereof, which are illustrated in the accompanying drawings. It should be noted that the components in the figures are not necessarily to scale, emphasis instead being placed upon illustrating the principles of the invention. Moreover, in the figures, like reference numerals designate corresponding parts throughout the different views. However, like parts do not always have like reference numerals. Moreover, all illustrations are intended to convey concepts, where relative sizes, shapes and other detailed attributes may be illustrated schematically rather than literally or precisely.
FIG. 1 is a cross-sectional side view of an imaging transducer assembly known in the art;
FIG. 2 is a block diagram of a medical imaging system known in the art;
FIG. 3 depicts a human heart as a potential site for use of the method and apparatus disclosed herein;
FIG. 4 depicts an exploded view of a region of the coronary arteries having an IVUS catheter positioned in a region of interest;
FIG. 5 depicts a user interface for displaying a longitudinal medical image known in the art;
FIG. 6 depicts a user interface for displaying a longitudinal medical image in accordance with a preferred embodiment of the present invention.
FIG. 7 depicts a user interface in accordance with another embodiment of the present invention.
The methods and systems disclosed herein are applicable to medical imaging, such as ultrasound imaging, of vessels, such as the coronary arteries as depicted in FIG. 3, or to any body cavity where the image is to be obtained over a region. With reference to FIG. 3, heart 99 includes coronary arteries 98 which follow a tortuous path along the surface of the heart. FIG. 4 shows an exploded view of curvature 97, having an IVUS catheter 21 disposed within a region of interest therein. Catheter 21 has distal end 22 and a proximal end (not shown), and is generally designed in accordance with imaging catheters known in the art. The catheter thus includes an intraluminal ultrasound imaging system, such as that shown in FIG. 1, capable of obtaining echographic images of the surrounding of catheter tip 22. The imaging system includes transducer 23 and its associated electronics for displaying an echographic data set, e.g., obtained by scanning transducer 23 over a 360-degree path 24 about distal tip 22 of catheter 21, or by a sector scan which makes a 60 or 90 degree scan. In an alternative embodiment, transducer 23 is replaced by a phased array as disclosed in Griffith et al., U.S. Pat. No. 4,841,977. Further, other imaging devices may be used, instead of, or in addition to imaging transducers, such as light based apparatuses for obtaining images through optical coherence tomography (OCT). Image acquisition using OCT is described in Huang et al., "Optical Coherence Tomography," Science, 254, Nov. 22, 1991, pp 1178-1181. A type of OCT imaging device, called an optical coherence domain reflectometer (OCDR) is disclosed in Swanson U.S. Pat. No. 5,321,501, which is incorporated herein by reference. The OCDR is capable of electronically performing two- and three-dimensional image scans over an extended longitudinal or depth range with sharp focus and high resolution and sensitivity over the range.
Scanning of the vessel interior is repeated many times during pull-back to obtain a plurality of echographic data sets taken at a sequence of positions 27 within vessel 98. In one embodiment, each echographic data set obtained during pull-back comprises a transverse or cross-sectional (i.e., r-Θ) image of the vessel at the point of the image, as shown in FIG. 4. An example of a cross-sectional image 120 is shown in FIG. 5. By "stacking" these images, a longitudinal image 105, i.e., an image along the longitudinal axis, or z axis, of the vessel may be generated, an example of which is also shown in FIG. 5. Such an image is known in the art as a "cut-plane" image. The longitudinal image 105 may be rotated along the z axis to display the image 105 at different angles, Θ, until desired features appear.
The longitudinal image 105 is typically generated by a software program, which may reside within the imaging console 20, shown in FIG. 2. The software program displays the image on a display device (not shown) of the imaging console 20. Turning to FIG. 6, the software program may include a user interface 100. The user interface 100 includes a first window 110, which displays a longitudinal image 105 of a vessel. As mentioned above, the longitudinal image 105 comprises of a plurality of r-Θ cross-sectional images obtained over time as the catheter 21 is being pulled back. Each of these r-Θ images may be regarded as frames 120, and the longitudinal image 105 may be displayed as an animation sequence presenting each frame 120 sequentially. These frames 120 are typically generated at a rate of approximately 30 frames/sec, and the catheter 21 is typically pulled back at a speed of approximately one-half mm/sec. Thus, the frames 120 are typically displayed very close together.
The user interface 100 may include control elements that allow a user to control the display of the longitudinal image 105. The control elements may include a playback element 130, a stop playback element 140, and an adjust cut-plane position element 125, which allows a user to rotate the longitudinal image 105 along the z axis. Also included is a frame control 150 element that allows a user to scroll through the frames 120, backwards and forwards, and select the display of a particular frame 120 within the sequence. The position of the user selected frame 120 within the sequence of the animation is known as the cursor position. The frame control 150 element includes a scrollbar button 155 that indicates the cursor position. The user interface 100 also includes a second window 180, which displays the frame 120, or cross-sectional image, corresponding to the cursor position. The control elements may be buttons, keys, sliders, scrollbars, virtual keys on a touch screen, or other user actuatable devices.
Generally, a clinician would analyze the image for abnormalities, and if an abnormality requiring one or more stents were discovered in the image, the clinician would visually estimate the length and position of the proper stent to be applied in the region of the abnormality. One approach to facilitate the estimation is to provide a graphical tool that allows a clinician to apply a graphical representation of a stent 160 over the longitudinal image 105 being analyzed. The clinician may be able to graphically adjust the size of the stent 160 to a desired size. One approach may be to drag a mouse pointer over a corner of the stent to adjust the size; however, stent sizes are typically pre-defined and pre-packaged by stent manufacturers, and thus the variety of different sizes may be limited. In such a case, it may be desirable to provide a graphical palette 165, or a predefined library, of one or more pre-defined stents with their sizes and other characteristics in the user interface 100. Because the library is predefined with the necessary dimensions and characteristics of each stent, the clinician may simply click on or otherwise select the desired stent within the palette 165 and drag the desired stent to a desired position on the longitudinal image 105 to determine if the selected stent is appropriate. One of ordinary skill in the art may appreciate that additional sizes, characteristics, or devices may be added to the palette 165 or library.
After the clinician has established a desired location, or position, on the longitudinal image 105 to place the stent 160, the clinician may place bookmarks in the image to record the desired location (preferably, one bookmark on each end of the location). The bookmarks essentially record the particular frames 120 that define the desired location within the longitudinal image 105. In addition, the graphical representation of the stent 160 may be transparent to maintain the visibility of the structure of the image 105. Providing a clinician a graphical tool to simulate the length and position of a stent within the image 105 facilitates in the selection of the proper stent size and position prior to placing the actual stent, which are costly and permanent implants, within the area of interest.
FIG. 7 shows a user interface 100 with a graphical tool for simulating the dimensions and position of a medical device, e.g., stent, within the patient's body. In this exemplary embodiment, the graphical tool comprises a rectangle 210 overlaid onto the longitudinal image 105 in the first window 110 and a circle 220 overlaid onto the frame 120 in the second window 180. Together, the rectangle 210 and the circle 220 define a cylinder in three-dimensional space with the rectangle 210 representing a longitudinal cross-section of the cylinder corresponding to the longitudinal image 105 and the circle 220 representing a radial cross-section of the cylinder corresponding to the frame 120. In this embodiment, the rectangle 210 and the circle 220 may be used to approximate the size and position of a stent to be applied within the patient's body, in which the stent has a generally cylindrical shape.
In an example, the image 105 and the frame 120 may be images of a blood vessel where the stent is to be applied. In this example, the clinician may move the rectangle 220 within the image 105 and adjust the dimensions of the rectangle 220 to visually approximate the desired position and dimensions of the rectangle 220. The clinician may move the rectangle 220 within the image 105, e.g., by clicking on the rectangle 220 with a mouse or touch pad to select the rectangle 220 and dragging the rectangle 220 to the desired position within the image 105. The clinician may adjust the dimensions of the rectangle 220 by clicking on a boundary of the rectangle 220 to select the boundary and dragging the boundary to adjust one or more dimensions of the rectangle 220. The boundary may darken when selected to visually indicate that the boundary has been selected. For example, the clinician may click on a side boundary of the rectangle 220 and drag the side boundary to adjust the length of the rectangle 220.
In an embodiment, the medical device being applied within the patient's body may only come in pre-defined dimensions. In this embodiment, the clinician may only adjust the dimensions of the rectangle 220 to one of a set of different dimensions corresponding to the pre-defined dimensions of the medical device. In an embodiment, the user interface may include a graphical palette 265 displaying a set of pre-defined rectangles that the clinician can apply to the image 105, where each rectangle corresponds to one of the pre-defined dimensions of the medical device. In this embodiment, the clinician can select one of the rectangles in the graphical palette 265 with the selected rectangle being applied to the image 105.
The clinician may also move the circle 210 within the frame 120 and adjust the dimensions of the circle 210 to visually approximate the desired position and dimensions of the circle 210. The clinician may move the circle 210 within the frame 120, e.g., by clicking on the circle with a mouse or touch pad to select the circle 210 and dragging the circle to the desired position within the frame 120. In this embodiment, movements of the circle 210 within the frame 120 causes corresponding movements of the rectangle 220 within the image 105. For example, moving the circle 210 upward within frame 120 causes the rectangle 220 to correspondingly move upward to track the movements of the circle 210. Similarly, movements of the rectangle 220 within image 105 causes corresponding movements of the circle 210 within the frame 120. The clinician may adjust the radius of the circle 210 by clicking on a boundary of the circle 210 to select the boundary and dragging the boundary to adjust the radius of the circle 210 to a desired radius. The boundary may darken when selected to visually indicate that the boundary has been selected. In this embodiment, changes in the dimensions of the circle 210 within frame 120 causes corresponding changes in the dimensions of the rectangle 220 within the image 105. For example, expanding the radius of the circle 210 within frame 120 causes the height of the rectangle 220 to correspondingly increase. Similarly, changes in the dimensions of the rectangle 220 within image 105 causes corresponding changes in the dimensions of the circle 210 within the frame 120.
Once the dimensions and positions of the circle 210 and the rectangle 220 are chosen, they provide an approximation of the size and position of the medical device to be applied within the patient's body. Although a circle and a rectangle were used in the exemplary embodiment, other shapes may also be used depending on the shape of the medical device to be applied within the patient. Also, different frames 120 may be displayed in the second window 180, e.g., by moving the scrollbar button 155, in which the position of the scrollbar button 155 corresponds to the frame currently displayed in the window 180. In this embodiment, the circle 210 corresponds to the frame 120 currently displayed in the window 180. Displaying different frames 120 in the second window 180 allows the clinician to visualize how the circle 210 fits within different radial cross-sectional images of the patient.
In the foregoing specification, the invention has been described with reference to specific embodiments thereof. It will, however, be evident that various modifications and changes may be made thereto without departing from the broader spirit and scope of the invention. For example, this invention is particularly suited for applications involving stents, but can be applicable for other medical devices. As a further example, each feature of one embodiment can be mixed and matched with other features shown in other embodiments. Additionally and obviously, features may be added or subtracted as desired. Accordingly, the invention is not to be restricted except in light of the attached claims and their equivalents.
What is claimed as new and desired to be protected by Letters Patent of the United States is:
1. A medical imaging system comprising:
an elongated tubular member having distal and proximal ends, configured to be inserted into a vessel of a patient;
an imaging device coupled to the distal end of the elongated tubular member and configured to emit one or more energy pulses and receive one or more echo signals; and
a console electrically coupled to the imaging device, wherein the console includes a computer-usable medium having a sequence of instructions which when executed by a processor causes the processor to execute a process comprising
generating a composite longitudinal image of the vessel by stacking cross-sectional frames generated as the imaging device is pulled back within a vessel, wherein the cross-sectional frames are stacked along a longitudinal axis of the composite longitudinal image, and
generating a user interface comprising a window for displaying the composite longitudinal image, controls for enabling a user to make adjustments to the composite longitudinal image, and a graphical palette comprising a plurality of graphical representations of medical devices each having different predefined size dimensions, the plurality of graphical representations comprising a first graphical representation, the first graphical representation having user-adjustable size dimensions that are adjustable solely to the predefined size dimensions of the remaining graphical representations of the graphical palette, wherein the user interface is configured and arranged to enable the user to select and drag the first graphical representation of the medical device within the window.
2. The medical imaging system of claim 1, wherein the window for displaying the composite longitudinal image is a first window, and wherein the user interface comprises a second window for displaying one of the cross-sectional frames of the composite longitudinal image.
3. The medical imaging system of claim 2, wherein the user interface comprises a scroll bar that allows the user to select the cross-sectional frame currently displayed in the second window.
4. The medical imaging system of claim 2, wherein when the selected first graphical representation is dragged to a portion of the first window a longitudinal view of the first graphical representation is overlaid onto the first window.
5. The medical imaging system of claim 4, wherein the longitudinal view of the first graphical representation comprises a rectangle.
6. The medical imaging system of claim 4, wherein when the first graphical representation is dragged to the first window, portions of the longitudinal image beneath the first graphical representation are at least partially visible through the first graphical representation.
7. The medical imaging system of claim 4, wherein when the portion of the longitudinal image onto which the first graphical representation is overlaid includes the cross sectional frame of the second window a cross-sectional view of the first graphical representation is overlaid onto the second window.
8. The medical imaging system of claim 7, wherein the cross-sectional view of the first graphical representation comprises a circle.
9. The medical imaging system of claim 7, wherein the user interface is configured and arranged to enable the user to move either the longitudinal view of the first graphical representation in the first window or the cross-sectional view of the first graphical representation in the second window.
10. The medical imaging system of claim 9, wherein movement of the longitudinal view of the first graphical representation in the first window causes a corresponding movement of the cross-sectional view of the first graphical representation in the second window.
11. The medical imaging system of claim 9, wherein movement of the cross-sectional view of the first graphical representation in the second window causes a corresponding movement of the longitudinal view of the first graphical representation in the first window.
12. The medical imaging system of claim 1, wherein the imaging device comprises an ultrasound imaging transducer assembly.
13. The medical imaging system of claim 1, wherein the medical device is a stent.
14. The medical imaging system of claim 1, wherein the controls of the user interface comprises controls configured and arranged for enabling the user to playback the composite longitudinal image frame-by-frame.
15. The medical imaging system of claim 1, wherein a location of the first graphical representation within the window may be bookmarked.
16. The medical imaging system of claim 1, wherein the controls comprise a cut-plane position adjustment element for enabling the user to rotate the composite longitudinal image along the longitudinal axis.
17. The medical imaging system of claim 1, wherein the size dimensions of the first graphical representation are user-adjustable while the first graphical representation is disposed within the window.
18. A non-transitory computer-usable medium having a sequence of instructions stored thereon which, when executed by a processor, causes said processor to execute a process for estimating the size, location, and position of a medical device to be applied within a vessel of a patient, the sequence of instructions comprising:
generating a longitudinal image of the vessel by stacking cross-sectional frames as an imaging transducer assembly is pulled back within the vessel, wherein the cross-sectional frames are stacked along a longitudinal axis of the composite longitudinal image; and
generating a user interface comprising a window for displaying the composite longitudinal image, controls for enabling a user to make adjustments to the composite longitudinal image, and a graphical palette comprising a plurality of graphical representations of medical devices each having different predefined size dimensions, the plurality of graphical representations comprising a first graphical representation the first graphical representation having user-adjustable size dimensions that are adjustable solely to the predefined size dimensions of the remaining graphical representations of the graphical palette, wherein the user interface is configured and arranged to enable the user to select and drag the first graphical representation of the medical device within the window.
19. A method for estimating the size, location, and position of a medical device to be applied within a vessel of a patient, comprising:
generating a user interface comprising a window for displaying the composite longitudinal image, controls for enabling a user to make adjustments to the composite longitudinal image, and a graphical palette comprising a plurality of graphical representations of medical devices each having different predefined size dimensions, the plurality of graphical representations comprising a first graphical representation, the first graphical representation having user-adjustable size dimensions that are adjustable solely to the predefined size dimensions of the remaining graphical representations the graphical palette, wherein the user interface is configured and arranged to enable the user to select and drag the first graphical representation of the medical device within the window.
US13/227,337 2005-02-28 2011-09-07 Systems and methods for estimating the size and position of a medical device to be applied within a patient Active 2025-03-08 US8529455B2 (en)
US11/069,206 US7892177B2 (en) 2005-02-28 2005-02-28 Systems and methods for estimating the length and position of a stent to be applied within a patient
US11/865,699 US8025622B2 (en) 2005-02-28 2007-10-01 Systems and methods for estimating the size and position of a medical device to be applied within a patient
US11/865,699 Continuation US8025622B2 (en) 2005-02-28 2007-10-01 Systems and methods for estimating the size and position of a medical device to be applied within a patient
US11/069,206 Active 2027-05-15 US7892177B2 (en) 2005-02-28 2005-02-28 Systems and methods for estimating the length and position of a stent to be applied within a patient
US11/865,699 Active 2027-12-25 US8025622B2 (en) 2005-02-28 2007-10-01 Systems and methods for estimating the size and position of a medical device to be applied within a patient
US7892177B2 (en) 2005-02-28 2011-02-22 Scimed Life Systems, Inc. Systems and methods for estimating the length and position of a stent to be applied within a patient
ES2524303T3 (en) 2006-05-08 2014-12-05 C.R. Bard, Inc. User interface and methods for a display device echographic
US8267927B2 (en) * 2007-01-24 2012-09-18 Koninklijke Philips Electronics N.V. Advanced ablation planning
US9101286B2 (en) 2008-11-18 2015-08-11 Sync-Rx, Ltd. Apparatus and methods for determining a dimension of a portion of a stack of endoluminal data points
JP5639764B2 (en) 2007-03-08 2014-12-10 シンク−アールエックス,リミティド Imaging and tools for use with the movement organs
US9629571B2 (en) 2007-03-08 2017-04-25 Sync-Rx, Ltd. Co-use of endoluminal data and extraluminal imaging
US9968256B2 (en) 2007-03-08 2018-05-15 Sync-Rx Ltd. Automatic identification of a tool
US9974509B2 (en) 2008-11-18 2018-05-22 Sync-Rx Ltd. Image super enhancement
US9144394B2 (en) 2008-11-18 2015-09-29 Sync-Rx, Ltd. Apparatus and methods for determining a plurality of local calibration factors for an image
US9095313B2 (en) 2008-11-18 2015-08-04 Sync-Rx, Ltd. Accounting for non-uniform longitudinal motion during movement of an endoluminal imaging probe
WO2010058398A2 (en) 2007-03-08 2010-05-27 Sync-Rx, Ltd. Image processing and tool actuation for medical procedures
JP5789195B2 (en) 2008-12-08 2015-10-07 シリコンバレー メディカル インスツルメンツ インコーポレイテッド The catheter system for image guided
US20180344174A9 (en) * 2009-09-23 2018-12-06 Lightlab Imaging, Inc. Lumen Morphology and Vascular Resistance Measurements Data Collection Systems, Apparatus and Methods
JP5721721B2 (en) * 2009-09-23 2015-05-20 ライトラボ・イメージング・インコーポレーテッド Lumen morphology and vascular resistance measurement data collection systems, devices and methods
EP2484289A4 (en) * 2009-09-30 2017-07-12 Terumo Kabushiki Kaisha Diagnostic imaging apparatus and method for controlling same
BR112013005592A2 (en) 2010-09-10 2017-06-20 Acist Medical Sys Inc apparatus and method for searching for medical imaging
JP2012200532A (en) * 2011-03-28 2012-10-22 Terumo Corp Imaging apparatus for diagnosis and display method
EP2723231A4 (en) 2011-06-23 2015-02-25 Sync Rx Ltd Luminal background cleaning
WO2013059712A1 (en) * 2011-10-21 2013-04-25 Plextronics, Inc. Improved synthesis of conjugated polymers via oxidative polymerization and related compositions
US9307926B2 (en) * 2012-10-05 2016-04-12 Volcano Corporation Automatic stent detection
US8913084B2 (en) * 2012-12-21 2014-12-16 Volcano Corporation Method and apparatus for performing virtual pullback of an intravascular imaging device
US9406129B2 (en) 2013-10-10 2016-08-02 Medtronic, Inc. Method and system for ranking instruments
ES2459244B1 (en) 2013-10-31 2014-11-14 Galgo Medical, S.L. Procedure for the determination of the final stent length before placement
WO2015073357A1 (en) * 2013-11-13 2015-05-21 Volcano Corporation Visually optimized intravascular imaging and associated devices, systems, and methods
US9713456B2 (en) * 2013-12-30 2017-07-25 Acist Medical Systems, Inc. Position sensing in intravascular imaging
US20150305631A1 (en) * 2014-04-25 2015-10-29 Medtronic, Inc. Real-Time Relationship Between Geometries of an Instrument and a Structure
JP2017526407A (en) * 2014-07-11 2017-09-14 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Apparatus for the treatment of conduits, systems, and methods
US9668818B2 (en) 2014-10-15 2017-06-06 Medtronic, Inc. Method and system to select an instrument for lead stabilization
JP2017534394A (en) * 2014-11-14 2017-11-24 コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. Percutaneous coronary intervention plan interface, and related devices, systems, and methods
WO2016092420A1 (en) * 2014-12-08 2016-06-16 Koninklijke Philips N.V. Devices, systems, and methods for vessel assessment and intervention recommendation
ES2578523B1 (en) 2015-01-26 2017-12-28 Galgo Medical, Sl Method, system and computer program for determining the porosity of a flexible porous structure when subjected to deformation
US20190038358A1 (en) * 2016-02-16 2019-02-07 Pentas Inc. Stent length estimation device, stent length estimation program, and method of estimating length of stent
US4841977A (en) 1987-05-26 1989-06-27 Inter Therapy, Inc. Ultra-thin acoustic transducer and balloon catheter using same in imaging array subassembly
US5000185A (en) 1986-02-28 1991-03-19 Cardiovascular Imaging Systems, Inc. Method for intravascular two-dimensional ultrasonography and recanalization
US5117831A (en) 1990-03-28 1992-06-02 Cardiovascular Imaging Systems, Inc. Vascular catheter having tandem imaging and dilatation components
US5203338A (en) 1990-12-17 1993-04-20 Cardiovascular Imaging Systems, Inc. Vascular catheter having low-profile distal end
US5321501A (en) 1991-04-29 1994-06-14 Massachusetts Institute Of Technology Method and apparatus for optical imaging with means for controlling the longitudinal range of the sample
US5368035A (en) 1988-03-21 1994-11-29 Boston Scientific Corporation Ultrasound imaging guidewire
US5538003A (en) 1995-05-18 1996-07-23 Hewlett-Packard Company Quick method and apparatus for identifying a region of interest in an ultrasound display
US5724977A (en) 1995-06-06 1998-03-10 Cardiovascular Imaging Systems Inc. Rotational correlation of intravascular ultrasound image with guide catheter position
US5749848A (en) 1995-11-13 1998-05-12 Cardiovascular Imaging Systems, Inc. Catheter system having imaging, balloon angioplasty, and stent deployment capabilities, and method of use for guided stent deployment
US5830145A (en) 1996-09-20 1998-11-03 Cardiovascular Imaging Systems, Inc. Enhanced accuracy of three-dimensional intraluminal ultrasound (ILUS) image reconstruction
WO2000041626A1 (en) * 1999-01-15 2000-07-20 Z-Kat, Inc. Apparatus and method for measuring anatomical objects using coordinated fluoroscopy
US6117104A (en) 1998-09-08 2000-09-12 Advanced Cardiovascular Systems, Inc. Stent deployment system and method of use
US6139544A (en) 1999-05-26 2000-10-31 Endocare, Inc. Computer guided cryosurgery
US6193657B1 (en) 1998-12-31 2001-02-27 Ge Medical Systems Global Technology Company, Llc Image based probe position and orientation detection
US6216029B1 (en) 1995-07-16 2001-04-10 Ultraguide Ltd. Free-hand aiming of a needle guide
US6245017B1 (en) 1998-10-30 2001-06-12 Kabushiki Kaisha Toshiba 3D ultrasonic diagnostic apparatus
US6308715B1 (en) 1999-03-24 2001-10-30 Pmd Holdings Corp. Ultrasonic detection of restenosis in stents
US6381350B1 (en) 1999-07-02 2002-04-30 The Cleveland Clinic Foundation Intravascular ultrasonic analysis using active contour method and system
US6379302B1 (en) 1999-10-28 2002-04-30 Surgical Navigation Technologies Inc. Navigation information overlay onto ultrasound imagery
US6381351B1 (en) 1999-11-24 2002-04-30 Direct Radiography Corp. Weighted inverse topography method for digital x-ray image data processing
US6475151B2 (en) 1997-11-19 2002-11-05 Scimed Life Systems, Inc. Aerogel backed ultrasound transducer
US6553386B1 (en) 1998-12-14 2003-04-22 Oliver Alabaster System and method for computerized visual diet behavior analysis and training
US6585654B2 (en) 1997-09-29 2003-07-01 Scimed Life Systems, Inc. Ultrasound imaging guidewire with static central core and tip
US6592526B1 (en) 1999-01-25 2003-07-15 Jay Alan Lenker Resolution ultrasound devices for imaging and treatment of body lumens
US20040068429A1 (en) 2001-10-02 2004-04-08 Macdonald Ian D Strategic organization plan development and information present system and method
WO2004051579A2 (en) 2002-12-04 2004-06-17 Philips Intellectual Property & Standards Gmbh Apparatus and method for assisting the navigation of a catheter in a vessel
US6786870B2 (en) 2001-10-23 2004-09-07 Olympus Corporation Device for examining a subject capable of marking a boundary range for insertion/retraction of an insertion/retraction member that is inserted in and retracted from the subject
WO2005011499A1 (en) 2003-08-05 2005-02-10 Hitachi Medical Corporation Tomogram constituting system and method
US20050107688A1 (en) 1999-05-18 2005-05-19 Mediguide Ltd. System and method for delivering a stent to a selected position within a lumen
2006-02-23 EP EP20060735883 patent/EP1853172A1/en active Pending
US6485422B1 (en) 1999-05-26 2002-11-26 Endocare, Inc. Computer guided cryosurgery
US6669635B2 (en) 1999-10-28 2003-12-30 Surgical Navigation Technologies, Inc. Navigation information overlay onto ultrasound imagery
US8025622B2 (en) 2005-02-28 2011-09-27 Boston Scientific Scimed, Inc. Systems and methods for estimating the size and position of a medical device to be applied within a patient
Huang et at, "Optical Coherence Tomography, Science," vol. 254, Nov. 22, 1991, pp. 1178-1181.
Office Communication for U.S. Appl. No. 11/069,206 mailed Dec. 8, 2009.
Office Communication for U.S. Appl. No. 11/069,206 mailed Feb. 17, 2009.
Office Communication for U.S. Appl. No. 11/069,206 mailed Jun. 3, 2008.
Office Communication for U.S. Appl. No. 11/069,206 mailed Nov. 12, 2010.
Office Communication for U.S. Appl. No. 11/069,206 mailed Oct. 30, 2007.
Office Communication for U.S. Appl. No. 11/865,699 mailed Jun. 22, 2011.
Wenguang, L. et al., "Semiautomatic Frame-to-Frame Tracking of the Luminal Border from Intravascular Ultrasound," Proceedings of the Computers in Cardiology Meeting, Venice, Sep. 23-26, 1991, New York, vol. Meeting 18.
Nelson et al. 1998 Three-dimensional ultrasound imaging
Von Birgelen et al. 1996 Morphometric analysis in three-dimensional intracoronary ultrasound: an in vitro and in vivo study performed with a novel system for the contour detection of lumen and plaque
Davidson et al. 1990 Intravascular ultrasonography versus digital subtraction angiography: a human in vivo comparison of vessel size and morphology
US9974509B2 (en) 2018-05-22 Image super enhancement
US7697973B2 (en) 2010-04-13 Medical imaging and navigation system
Isner et al. 1990 Percutaneous intravascular US as adjunct to catheter-based interventions: preliminary experience in patients with peripheral vascular disease.
US8303505B2 (en) 2012-11-06 Methods and apparatuses for image guided medical procedures
US6556695B1 (en) 2003-04-29 Method for producing high resolution real-time images, of structure and function during medical procedures
EP1088515B1 (en) 2006-06-07 Vascular reconstruction
JP3167367B2 (en) 2001-05-21 Cardiovascular diagnostic apparatus
JP5281740B2 (en) 2013-09-04 3-dimensional representation determination system of the tubular organ
CN1720004B (en) 2012-02-08 Auxiliary equipment and a method of navigating a catheter in a vessel
US7729746B2 (en) 2010-06-01 Three-dimensional co-registration between intravascular and angiographic data
US8449465B2 (en) 2013-05-28 System and method for characterizing vascular tissue
EP1916947B1 (en) 2010-04-14 Medical image analysis
US20080287777A1 (en) 2008-11-20 System and method to register a tracking system with an intracardiac echocardiography (ice) imaging system
JP5232012B2 (en) 2013-07-10 Control panel for medical image system
US20120004529A1 (en) 2012-01-05 Automatic display of previously-acquired endoluminal images
CA2438089C (en) 2013-01-22 Medical imaging and navigation system
JP6099562B2 (en) 2017-03-22 Combination intraluminal data and extraluminal imaging
US20120004537A1 (en) 2012-01-05 Co-use of endoluminal data and extraluminal imaging
US9775538B2 (en) 2017-10-03 System and method for determining the position of the tip of a medical catheter within the body of a patient
JP4993982B2 (en) 2012-08-08 Catheter device and treatment device
EP1732461B1 (en) 2011-04-06 System for vascular border detection
US6148095A (en) 2000-11-14 Apparatus and method for determining three-dimensional representations of tortuous vessels


I would definitely place this biscotti in the after-dinner category, with either coffee or black tea.
Combine the oil, sugar, eggs and molasses. In another bowl, whisk together the flours, baking powder and spices. Mix the dry ingredients into the wet ingredients with a wooden spoon to form a stiff dough.
Divide the dough in half and shape each half into rolls the length of a baking sheet lined with parchment paper. Pat the rolls down to flatten to about a 1/2-inch thickness.
I definitely had some fun with the decorating, and the chocolate is easier to control than I expected.
Bake the biscotti at 375 degrees for 25 minutes. Remove from the oven and let cool for a few minutes.
Cut the biscotti into 1/2-inch thick diagonal slices. Return the biscotti to the baking sheet and bake for another 5 to 7 minutes, laying cut-side up.
Melt the white chocolate in a double boiler or in a microwave. Pour the melted chocolate into a baggie and cut a tiny corner off one end of the baggie to pipe over the biscotti.
Makes about four dozen biscotti.
*During the month of December, we're offering some simple biscotti recipes that can be quickly snatched for breakfast with coffee or enjoyed with tea after a long day of holiday preparation. All of our Crunch Time recipes can be found here.
I expected these to taste a bit more Christmas-y, but they just seemed well-spiced to me instead. Which is fine, I'm not exactly thinking about Christmas right now.
Apple topping is clearly optional - I just like the ginger-apple flavor profile.
Combine all dry ingredients in a medium bowl. In a separate bowl, whisk together the wet ingredients and pour over dry ingredients, stirring just until combined.
Heat a skillet over medium heat. When skillet is hot, add a tablespoon or so of oil. Make your pancakes just like you would any other time (I think we've explained this well enough in our other Lookin' Hot posts). I would suggest making smaller pancakes with this batter, as larger ones puff up quite a bit and stand the chance of just being mushy. Shoot for teacup-sized pancakes.
Makes about eight-10 (small-ish) pancakes.
In March we'll post our favorite flapjack recipes as part of Lookin' Hot, Cakes. You can find all of our pancake recipes here.
These cookies are basically a cross between gingerbread cookies and chocolate chip-walnut cookies. Perfect in every way.
Chop chocolate into 1/4-inch chunks (unless you were smart enough to get chips or morsels); set aside. In a medium bowl, sift together flour, ground ginger, cinnamon, cloves, and cocoa.
Beat butter and grated ginger until combined. Add brown sugar and molasses, again beat until combined.
In a small bowl, dissolve baking soda in 1 1/2 teaspoons boiling water. Beat half of flour mixture into butter mixture. Add in baking-soda mixture, then remaining half of flour mixture. Mix in chocolate.
Place dough onto a piece of plastic wrap. Pat dough out to about 1-inch thick; seal with wrap and refrigerate until firm, 2 hours or more (I prefer overnight).
Roll dough into 1 1/2- inch balls. Dip the top half into the chopped walnuts, pressing to make sure they stake in the dough. Place on a cooking sheet with either Silpat or parchment paper, leaving 2 inches between each cookie. Refrigerate for about 10 minutes until the dough firms back up (it is very sticky).
Bake at 325 for about 10 to 12 minutes. The cookies will seem rather soft when you take them out, but they firm up as they cool. DO NOT overbake or else you will be eating hockey pucks for a few days.


text:
Number of local wrestlers take home state titles
By Jon Sapertein Herald Writer
Saturday, February 18, 2012 11:57pm
SportsEdmonds-Woodway HIgh SchoolEverett High SchoolGranite Falls High SchoolHigh school sportsKamiak High SchoolLake Stevens High SchoolSnohomish High SchoolSportsStanwood High SchoolWrestling
TACOMA — Awaiting his 182-pound 3A final at Mat Classic XXIV Saturday night, Glacier Peak's Sean Elledge stood in the corner of the Tacoma Dome, jogging in place while listening through earbuds to "Can't Be Touched" by rapper and former light heavyweight champion boxer Roy Jones Jr.
The song proved prophetic.
Elledge dismantled Mercer Island's Phil Frazier on the way to an 8-0 major decision, beating the guy that Washington Wrestling report ranked as No. 1 in the 182-pound weight class entering the tournament.
"Me and my coach made a game plan and I stuck to it," Elledge said of his strategy against Frazier, who a year ago finished third at state while wrestling in the 171-pound weight class.
"I wore him down and I started just tearing him apart. It's amazing right now. I'm so happy that I won it. It's always good to go out there and dominate."
In 2011, Elledge placed fifth at 160 pounds, but he and his cousin Jacob Elledge broke through this year, as Glacier Peak's second and third individual finalists in school history. In 2011, Josh St. Marie became the school's first individual champion.
"It's good for me and my cousin to get there (the finals) because my cousin is the one that's pushing me," Sean said. "He's always telling me how good I am and I'm pushing him. We're just pushing each other in the room to try to make us our best. It was good to see my cousin there. I was happy for him he deserved it."
Both are juniors and third-year coach Bryan Mossburg is happy with the progress of his program at the relatively new school.
"We've got a lot of young kids that are excited about wrestling and we've got a lot of them down here watching their teammates that are on the verge and now they've seen it with them breaking through and both getting into the finals," Mossburg said. "Coming back next year. That's huge. It's exciting for these guys."
Sean hopes that the lessons learned this week on the mat in Tacoma translate to the gridiron where he is a running back for the football team.
"I think it makes me a way better football player," Sean said.
Jacob Elledge, who entered Mat Classic ranked seventh, dropped the 145-pound final to Sedro-Wooley's Brady Mast, who was ranked first. It was Jacob's third loss in three weeks to the S-W senior after meeting him in the finals of the district and regional tournament.
Several local wrestlers rode upsets the finals Saturday, perhaps most impressive was Lake Stevens' Eric Soler in the 126-pound 4A class. The Vikings junior defeated two undefeated wrestlers in the semifinals and finals both of which were state champions in 2010.
"It's unbelievable especially with a kid that's had to deal with an ACL reconstruction a year ago," Lake Stevens coach Brent Barnes said. "He comes through maybe the toughest weight class."
Against Steven Hopkins of Tahoma in the final Soler lead 6-4 but let Hopkins back in the match with a final second takedown at the end of the third period. In overtime Soler made one quick move to win the sudden-death match 8-6.
"I had it at the end of the match and I was just getting lazy," Soler said. "I was like (shoot) I've got to step back up."
Soler's win helped propel Lake Stevens to the edge of a team trophy awarded to the 4A teams with the top four scores. The Vikings finished with 91 points. Tahoma was the overall champion with 190 points.
Equally impressive on the 3A side was Everett's Jessie Lopez who won a 7-6 decision against Yelm's Dillon Harris at 132 pounds. Lopez was an underdog against the top-ranked Harris and had lost to the Yelm junior Dec. 5th 8-4.
"I went in not thinking win or lose," the Seagull junior said. "I wanted to wrestle as hard as I can."
Lopez overcame a 6-5 deficit with 23.3 seconds left in the match to win. Everett coach Brien Elliott knew after the Dec. 5 bout that they would see him again and taught Lopez two moves to practice. Lopez spent 30 minutes every day outside of regular preparation on those moves, which is how he came back in the end. It was amazing dedication for an opponent that based on chance, Lopez may have never faced again this year.
"He executed it brilliantly," Elliott said. "We knew he had him."
The lone area favorite on the boys side, entering the finals was perhaps the smallest boy wrestler in the Tacoma Dome—Edmonds-Woodway's 5-foot-2 Noah Cuzzetto wrestling at 106 pounds.
Cuzzetto came back from the dead both in Saturday's final and on the season to take the 106-pound title with a 6-4 win over Graham Kapowsin's Spencer Schroeder.
Four weeks ago Cuzzetto had an x-ray on his foot that revealed a broken foot, presumably ending his season.
"I was pretty devastated," Cuzzetto said. "I knew I would have a good run at state this year."
Several days of rest and a second opinion revealed that a growth plate in the sophomore's foot came out of place, but naturally fell back to where it was supposed to be.
"I felt like I had a second life," Cuzzetto said. "Like it was meant to be. Like I was going to win this."
During the district and regional tournament all the way to the state finals no one got ahead of the Warrior on points until he trailed Schroeder 4-2 entering the third period Saturday night.
"He's pretty comfortable in those situations," E-W coach Brian Alfi said.
A takedown and a near fall later and Cuzzetto rode Schroeder's back to the crown.
"I was a little nervous, but I knew I could pull it out," Cuzzetto said. "I just needed to wrestle hard. I had a few tricks up my sleeve. That's what nine years of wrestling gives you. You always have something in reserve."
The season also ended in tears for some of the area's best.
Lake Stevens' Brandon Johnson lead Central Kitsap's Kyle Lanoue in the second period but went to overtime tied 1-1, before succumbing to a near fall to end the tournament.
Arlington's Blake McPherson entered the morning's semifinals undefeated on the season but lost a brutal match 6-5 to the state's top ranked wrestler, who went on to finish second. In his first consolation bout against Union's Bryson Page, who he defeated 20-10 during the regional tourney, he injured his shoulder and dropped a 4-2 decision. McPherson ended up sixth after injury defaulting to Snohomish's Nathan Proffitt who took sixth.
At Tacoma Dome
Team results—6. Lake Stevens 91, 9. Snohomish 61, 13. Stanwood 34, 14, Marysville Pilchuck 34, 15. Edmonds-Woodway 31, 19. Kamiak 27, 38. Arlington 10.
106—Noah Cuzzetto (E-W), champion def. Schroeder (G-K) 6-4, OT in final; David Garcia (Kam), third pinned Alonzo (Aub) 4:58; 113—Gino Obregon (Sno), third def. Dykman (TB) 5-0, Joshua Heitzman (Kam), seventh pinned Hershel (Univ) 0:20; 120—Josh Langstaff (Stan), sixth pinned by Gleed (ML) 4:26; 126—Eric Soler (LS), champion def. Hopkins (Tah) 8-6, OT, Killian Page (MP), sixth lost to Tickman (Iss) 14-10; 132—Christian Mendoza (MP), fifth pinned Gonzalez (Eis) 0:54, Greg Eagle (Sno), eighth lost to Thelen (CV) 4-2; 138—Kinsey Johnson (LS), third def. Munding (Mead) 7-0; 145—Drew Hatch (MP), sixth lost to Mjelde (Tah) 11-2, Max Welsh (Mar), seventh pinned Lee (Beth) 2:35; 152—Zach Schut (Stan), fifth def. Reynolds (Uni) 11-8; 160—Ammon Morrill (Sno), sixth lost to Davis (CV) 5-2; 170—Kyle Bennett (Stan), fifth inj. def. over Harper (East); 182—Ryan Olliges (LS), third pinned Dennis (Shel) 3:23, Peter St. Marie (Sno), eighth lost to Edrington (Chi) 6-5; 195—Nathan Proffit (Sno), fifth inj. def. over Blake McPherson (Arl), McPherson, sixth lost to Proffit, inj def.; 220—Luke Reinhard (Sno), eighth lost to Volz (Mead) 10-6; 285—Brandon Johnson (LS), second lost to Lanoue (CK) 6-1 in final.
Team results—12. Glacier Peak 52, 15. Shorecrest 43, 16. Everett 41, 26. Oak Harbor 26.5, 32. Lynnwood 20, 34. Meadowdale 18.5, 48. Marysville Getchell 5
106—Luis Cardona (M-G), eighth lost to Osborn (Univ) 9-5; 113—Jesus Escalona (Shc), fifth pinned Guerrero (Sunn) 4:21; 120—Mathew Floresca (Shw), fourth lost to Wicken (Kel) 3-1; 126—Cody Fakkema (OH), third pinned Gonzalez (Sunn) 2:22; Calkins (Lynn), seventh pinned Morf (Timb) 1:23; 132—Jessie Lopez (Eve), champion def. Harris (Yelm) 7-6 in final; 145—Jacob Elledge (GP), second lost to Mast (S-W) 10-2 in final; 152—Hunter Lord (Lynn), eighth pinned by Tibbetts (Odea) 1:54; 170—Connor Boyce (Eve), fourth lost to Petrechko (LW) 7-4; 182—Sean Elledge (GP) champion def. Frazier (MI) 8-0 in final; 285—Ian Bolstad (Shc) champion def. Cosby (Univ) 8-4 in final.
Class 2A: 106—Chris Jenkins (GF), seventh def. Collins (RAL) 4-0; 145—Carlos Toledano (Ced), fifth def. Miller (DP) 6-2; 160—Cody Paxman (Ced), second lost to Prentice (Tum) 8-5; 170—Martin Vakamoce (Ced), sixth pinned by Churchill (Cent) 2:32; Brandon Todd (AM), eighth pinned by Duran (Aber) 1:30; 182—Conner Kruse (AM), eighth pinned by Goodpaster (Sel) 4:12; 285—Robby McNair (Ced), second pinned by Postlewait (MB) :48.
Everett 4, Vancouver 3 (SO)
4A Boys Basketball District 1 Championship game: Jackson outlasts Snohomish, 60-57

redpajama_set_name: RedPajamaCommonCrawl


text:
MTV to Re-Air Mac Miller's Reality Show for a Limited Time
Tosten Burks
Tosten Burks Published: September 12, 2018
MTV is bringing back Mac Miller's reality television series in the wake of his death, The Blast reports today (Sept. 12). The network hasn't announced a broadcast date, but plans to re-air episodes of Mac Miller and the Most Dope Family as part of a slate of content paying tribute to the late rapper and producer.
The show's two seasons, originally broadcast in 2013 and 2014, followed Miller's life after he moved to Los Angeles following the runaway success of his 2011 album Blue Slide Park. In that time, Mac frequently hosted some of the city's best young artists while producing what would become his own critical breakthrough, 2013's Watching Movies with the Sound Off, as well as several acclaimed mixtapes including Vince Staples' Stolen Youth.
Earl Sweatshirt, who contributed to two songs on Watching Movies, reflected on that period in the hours after TMZ first reported Friday (Sept. 7) that Miller died of an "apparent overdose."
"THE MAN WAS TOO GENEROUS ! HE EXTENDED HIS HOME TO ALL OF US . PEACE TO THE MILLER FAMILY AND THE WHOLE EXTENDED FAMILY. WE HURTIN," Earl tweeted.
Miller's death at the age of 26 has sparked tributes across the music industry. Drake, Childish Gambino and Elton John are just a few of the artists to dedicate performances in recent days to the musician born Malcolm McCormick. Mac's hometown of Pittsburgh, for its part, hosted a vigil at Blue Slide Park's eponymous location.
The rapper's official cause of death has not yet been determined. An autopsy by Los Angeles County's coroner was inconclusive and authorities are reportedly waiting for the results of a toxicology report before making a final determination.
See Photos of Mac Miller's Different Looks Over the Year
Source: MTV to Re-Air Mac Miller's Reality Show for a Limited Time
Filed Under: mac miller
Categories: Entertainment News, News, Television


text:
Anthony Anderson is a writer, producer and award-winning actor who has starred in dozens of movies and TV shows. He stars in and is executive producer of the new comedy Black-ish.
Get updates about Anthony Anderson and recommended reads from Simon & Schuster.
Books by Anthony Anderson


text:
Alexander McDougall painted by Edgar Brown Smith, Frances Tavern Museum, New York City
Champagne, Roger J. Alexander McDougall and the American Revolution in New York. Schenectady, NY: Union College Press, 1975.
MacDougall, William L. American Revolutionary: A Biography of General Alexander McDougall. Contributions in American History, no. 57. Westport, Conn: Greenwood Press, 1977.
Memoirs and Papers
Guide to Alexander McDougall papers in the Biographical Directory of the US Congress, Alexander McDougall, 1731-1786, Guide to Research Collections which include manuscripts at the New York Historical Society, Historical Society of Pennsylvania, Huntington Library, The Library of Congress, The Morgan Library, The New York State Library, The Rosenbach Museum and Library and the Yale University Library.
Alexander McDougall painted by Edgar Brown Smith, Fraunces Tavern Museum, New York City


By Roger Miller. This edition: Interactive Download. Christmas, Country, Pop. 2 pages. Published by Hal Leonard - Digital Sheet Music (HX.9677).
By Roger Miller. Standards. Piano/Vocal/Guitar. 3 pages. Published by Hal Leonard - Digital Sheet Music (HX.219818).
By Roger Miller. This edition: Interactive Download. Country. Piano/Vocal/Guitar. 2 pages. Published by Hal Leonard - Digital Sheet Music (HX.21158).


a. Explain the production possibilities frontier (PPF).
b. Analyse what it means for the PPF to be bowed out from the origin (curved), and what it means for the PPF to be a straight line.
c. State the Law of Increasing Opportunity Cost and explain why it holds.
7. what are the benefits of households into international trade?


Our Lumber Cover & Wrap protects your lumber from Sun and Rain!
Unlike Trees, Lumber needs to be covered! Our Lumber Cover & Wrap protects your lumber from Sun and Rain! Our woodcovers, also known as lumber wrap, are made from virgin PE material so that you will not have any issue on strength or for recycling. The extended UV protection allows a safe outdoor storage. All our products are being manufactured according to high quality standards in our fully integrated ISO certified production sites.
A lumber cover can have the same aesthetic characteristics as lumber wrap, and if applied correctly, will have a more consistent look than a lumber wrap pallet (due to inconsistencies in cutting lengths). With one end fastened by staples, the tightness of the package is determined by the applicator, who has the power to determine the tension on the fit.
Why use Lumber wrap for your application?
When considering a basic package for lumber and wood products, lumber wrap is the answer. If you are looking for a way to distinction your company, you can go with Digital printing on your lumber wrap. While sewn lumber bags area excellent option for packaging your wood related products, rolls of plain standard lumber wrap allows for variables in your board length, and work great on end-line production/packaging stations.
We can palletize for easy handling.


during this pioneering learn Vivienne Richmond finds the significance of costume to the nineteenth-century English terrible, who valued garments not just for its sensible application, but in addition as a principal point within the production and statement of collective and person identities. in this interval of quick industrialisation and urbanisation formal costume codes, company and institutional uniforms, and the unfold of city models changed the casual costume of agricultural England. This laid the principles of contemporary renowned costume and generated fears concerning the visible blurring of social barriers as new modes of producing and retailing accelerated the wardrobes of the bulk. although, an important impoverished minority remained outdoor this method. Clothed through diminishing parish counsel, increasing paternalistic charity and the second-hand exchange, they shaped a 'sartorial underclass' whose fabric deprivation and visible contrast used to be a reason for actual ache and mental trauma.
Coconut Oil on your pores and skin – Nourishing Your physique From the skin In is a real hard work of affection. i like coconut oil for lots of purposes yet were so very inspired with it as i've got used it on my pores and skin. Coconut oil is the main nourishing oil you could placed onto your dermis and into your physique. natural virgin (unrefined) coconut oil is the simplest common factor for pores and skin lotion.
Garments is the outward and visual signal of style, discrimination, social angle and standing. In each tradition, women and men pay huge, immense recognition to the trivia of gown and visual appeal. This authoritative examine seems to be at either the social and actual points of garments. It strains the background and improvement of garments from the earliest instances to the laptop age, displaying how materials, ornament, form and constitution, mirror and are plagued by tradition and know-how.
On the center of this anthology lies the area of style: an idea that pervades the world of garments and get dressed; appearances and stylish manners; inside layout; rules and attitudes. right here 16 papers specialize in the Nordic international (Denmark, Norway, Sweden Finland, Iceland, the Faroe Isles and Greenland) in the timeframe advert 1500–1850.
A gorgeous visible number of greater than fifty varied braided hair kinds, with unique directions and worthy photos that exhibit tips on how to create them. From the massive monitor to the runway to the purple carpet, braided hairstyles have by no means been extra well known than they're at the present time. even if you must game beautiful, complicated twists, pull again your hair for routines or the large video game, or costume up for a marriage or formal occasion, the massive publication of Braiding has all of the seems and directions to motivate and express you ways.


Starting from a digital list does not usually require enrichment via a master source. Libraries use a standard exchange format, MARC, including WorldCat. All major library management systems can import and export MARC. When a library switches to a new system, they usually just export their existing catalog data in MARC format and import that data into the new system. The tricky part is that most library management systems have unique features and workflows, and stores extra information internally to manage those systems. As an example, there are numerous ways systems might store item location and status. So a transition usually involves cleaning up the original data, translating local system data into MARC fields which can be imported in the new system, massaging incompatible data into forms the new system can store in its own local rules, and filling in data on the new system that could not be exchanged from the old system. But that is only local system stuff. The basic cataloging information follows a standard that can (in principle) be easily exchanged.
As you suspected, systems do not actually store the exchange format MARC as their master catalog (the Source of Truth). Usually it is stored in a database, with most systems using a proprietary internal data design. Most systems can display the data in MARC format for the purposes of cataloging. Maintenance and additions are handled either by manual entry or retrieval of records in MARC format from a vendor or a master source like WorldCat. New and updated MARC records can be imported individually or in batch.
One interesting development in library management systems is the growth of cloud catalog services. WorldCat came out with such a system a few years ago, named WorldShare Discovery, but there are several others. In this system, the cloud service stores the catalog data and serves as the Source of Truth. In WorldShare Discovery, for instance, the library picks which WorldCat records are in its "local" catalog. New records created by one Discovery library are added to WorldCat and can be used by all other libraries using WorldCat. Changes to the WorldCat master record are reflected immediately in all Discovery catalogs. The library can add some local data as well, but for the most part, the WorldCat master record is also the local record.
Thanks for taking the time to answer. This is exactly the type of info I'm looking for.
1. Starting From Paper: A process that A) turns the Paper Card Index into Digital List, B) requires enriching it via a Master Data Source like WorldCat, and C) loads the list into the library.
2. Starting from a Digital List: Which I assume still requires B and C, from above.
After initial upload, is that Digital List treated as an ongoing Source of Truth (SoT) that is continuously mastered outside the library and incrementally synched with the data loaded into the library? Or, after initial upload, is that list discarded and the library, itself, is used to control master inventory (either through incremental manual entry or scanning)? I'm under the impression that it's the latter.
> but there are heaps of systems out there.
> account you can run an advanced search eg "all libraries in New Zealand using Alma".
> to add holdings and local barcodes/RFID/whatever).
> import those from whatever format you're already using.
> your Libraries and all Library Artifacts?
> things like CSV seed files or do you enter all artifacts one at a time?
> return e-mail or telephone and then delete this e-mail together with all attachments from your system."


Document folder as accessory for messenger bag, with three compartments for papers and documents, 2 pen holders, fixed with push buttons, sturdy back ensures clean and proper storing of documents.
Will this fit with the brompton o-bag?
Yes this would, but the O-bag does have internal organisation pockets etc.


COOPERATION, COORDINATION AND CONVERSATION CAN PAY OFF. That's what the team behind the energy upgrade of Hilton Los Angeles/Universal City discovered when the hotel underwent a $7 million energy-saving retrofit, the biggest property-assessed clean energy (PACE) commercial project in the nation. The hotel chain reported an annual energy and maintenance savings of $800,000 in its first year after completion of the work. That is nothing to scoff at.
The five-month project, which ran from November 2013 until April 2014, came together as a result of a series of connections. In late 2012, Stanley Rodriguez, manager of special projects at the Hilton, attended a workshop in regard to sustainability certifications sponsored by the United States Green Building Council-Los Angeles (USGBC-LA).
"We knew then that our Energy Star rating wasn't what we wanted and that we had a significant need to reduce our energy footprint," said Steve Thompson, facilities manager, Hilton Los Angeles/Universal City.
The USGBC-LA stepped up to assist the Hilton in its efforts to launch a project to increase the property's energy efficiency by referring the hotel to The Energy Coalition (a California-based nonprofit 501(c)( 3) organization that empowers governments, businesses and schools to be energy-responsible communities). The Energy Coalition, in turn, involved the Los Angeles chapter of the National Electrical Contractors Association (LA/NECA). LA/NECA then deployed ReNewAll, a California sustainability firm that works with multiple governmental financial programs to develop energy-efficiency, demand-response and energy-storage projects.
O'Bryant Electric's superintendent Greg Zickovich and project manager Gary Leder worked with Ben Moore, then sales representative of TCP Lighting, and Charles Norris of Gexpro, a distribution company, to specify lamps and fixture upgrades throughout the property.


Butter 4 ramikins, divide cheese among ramekins and press in bottom.
Break an egg over cheese in each ramekin.
Place ramekins on cookie sheet & bake in 350° oven for 20 min.
Meanwhile, toast muffins & on med heat, melt butter in saucepan.
Add chives & onion & cook a few min. more.
Remove ramekins when yolks are set but not dry. Let cool slightly.
Slide knife around sides and remove egg to a plate on top of ½ muffin, cheese side up.
Pour sauce over egg & muffin& serve.


text:
in NEWS / INFO
Former Senior Director of Content Acquisition at Google Joins Blockchain Gaming Distribution Platform Ultra
by Blockchaingamer
Ex-Partnership and Strategy Advisor to Ultra, Edward Moalem, appointed as its new Chief Strategy Officer
Cupertino, California — July 25, 2018 — Ultra, the Estonian-based company building a first-class PC game publishing platform and marketplace, has announced the appointment of Edward Moalem as Chief Strategy Officer (CSO). He previously served on Ultra's advisory board as its Partnership and Strategy Advisor since January 2018.
Commenting on the company's growth trajectory, Moalem said, "Ultra is the preeminent gaming publisher and is making gaming fun again. The company has strong business fundamentals upon which we can continue to build in the months and years to come. The team have developed a long-term plan for the technology as well as the product, and what Ultra is trying to achieve is realistic, applicable, and will disrupt the gaming industry now and in the future."
As CSO, Moalem's role will focus on developing relationships and connecting with game developers and publishers to increase the volume of content available on the blockchain-based platform. Moalem brings more than 25 years of technology experience to Ultra, having previously held positions at leading gaming companies and major corporations, including NewsCorp, Apple, and Google. While working at Google as Senior Director of Content Acquisition, Moalem initiated and brokered the acquisition of Adscape, an in-game advertising company.
He also initiated and brokered the first DRM deal with Disney for their PC version of Toy Story. Other notable experience includes working with Microsoft to encrypt and distribute Office2000, as well as brokering the first networking deal between the GameSpy publisher services group and Nintendo.
Commenting on the appointment, Nicolas Gilot, Co-CEO of Ultra, said, "Edward's appointment is important in bolstering our new business development at Ultra. His extensive technical expertise, combined with his professional gaming services background, make him the perfect fit for leading us through the evolution of the gaming industry. Using Edward's industry connections, we hope to increase the content available on the platform as we continue to innovate. The gaming industry is one of the fastest adopters of new technology, and we want to ensure we are agile enough as a platform to react to its exciting idiosyncrasies."
Founded in 2017, Ultra is the next-generation games distribution blockchain-based platform. Backed by former executives from leading gaming companies including Atari, Xbox, and Time Warner, Ultra aims to be fairer to both developers and players. Developers will be provided with the flexibility of a custom-built platform, while players will be able to earn financial incentives through participation in activities including beta tests, market studies, and the curation of games. Ultra provides access to third-party game services and exclusive content via its open platform .
For more information, visit https://ultra.io
Ultra is building a first-class PC game publishing platform and marketplace that puts an end to the current distribution monopoly. Founded in 2017 by Nicolas Gilot and David Hanson, Ultra's vision is to provide developers with the flexibility of a custom-built platform while bringing exciting innovations and financial incentives to players, making the development of a new breakthrough game distribution platform possible.
About Edward Moalem
Edward is the Chief Strategy Officer of Ultra, a blockchain-based, game publishing platform designed to put an end to the current distribution monopoly. Edward has extensive experience in the gaming industry, having previously worked for companies including Apple, Google and NewsCorp. Through his work, including licensing games and brokering deals, Edward has generated $1.8 billion in revenue and value for his clients.
About Nicolas Gilot
Nicolas Gilot is the Co-CEO of Ultra, a blockchain-based, PC game publishing platform and marketplace that puts an end to the current distribution monopoly. A serial entrepreneur and strategist, Nicolas led Xiaobawang as CSO, a game console project undertaken in partnership with AMD with a budget over US$100m. He is responsible for the success of numerous businesses including game studio PixelBeam which was later acquired by Kingsoft (Xiaomi) and multiple game/app projects including Plants VS Zombies, Highnoon and The Economist. As founder and director of consulting agency Gamika, Nicolas has extensive knowledge in monetization strategy, product design, data analysis and project management.
About David Hanson
David is Co-CEO of Ultra, a blockchain-based, game publishing platform designed to put an end to the current PC game market status quo. He has over 18 years of experience founding companies and operating them as CEO. He led Xiaobawang as CEO to develop a new video game console targeted at the Chinese market, and built it in partnership with AMD with a budget north of US$100m. He also founded Pixelbeam, a video game studio later acquired by Kingsoft (Xiaomi).
Original Press Release Issued From: Waschman https://wachsman.com & Ultra https://ultra.io
Written by Blockchaingamer
in - Collectible
Just what the Blockchain needs – Pirates. Arrrghh!
Wars of Cutieland: Choose your strategy to decide the fate of the blockchain world.
in - Simulation
A New Way of Monetizing NFTs: Sale of CryptoMotors' Luxury Cars in NeoWorld
"France Edition 2019" Formula 1 NFT auction starts 11 July 2019
CryptoMotors is launching its second car design challenge.
in - Action/Adventure
ChainGuardians Game Teaser
2 For 1 Game Feature Contest (Round 2) (Open list) (4 submissions)
Bitizens Preview Release Has Launched!


text:
"""LibreKPI: the freedom of knowledge

This app implements web service for students
"""

import yaml

import tornado.httpserver
import tornado.ioloop
import tornado.web
import tornado.auth
import tornado.options
import tornado.autoreload
from tornado.options import define, options

from motorengine import connect

from jinja2 import Environment as Jinja2Environment, FileSystemLoader, TemplateNotFound

from webassets import Environment as AssetsEnvironment
from webassets.ext.jinja2 import AssetsExtension

import os
import sys

from librekpi import SRC_DIR, PRJ_ROOT, __config__
from librekpi.utils import routes

from librekpi.controller import MainHandler, UserPortfolioHandler, \
    LoginHandler, AuthLogoutHandler, \
    GoogleOAuth2LoginHandler as GoogleLoginHandler, \
    FacebookGraphLoginHandler as FacebookLoginHandler, \
    TwitterLoginHandler
from librekpi.rest_controller import ApiHandler

define('version', default='dev', help='Version settings (default: dev)')

class App(tornado.web.Application):
    """Main Tornado app"""
    def __init__(self, settings):
        handlers = routes.get_routes() + [
            tornado.web.URLSpec(r'/login/google', GoogleLoginHandler, name='login_google'),
            tornado.web.URLSpec(r'/', MainHandler, name='home'),
            tornado.web.URLSpec(r'/(.*)', tornado.web.StaticFileHandler, {'path': os.path.join(PRJ_ROOT, 'static')}, name='homestatic'),
            tornado.web.URLSpec(r'/login/', LoginHandler, name='login'),
            tornado.web.URLSpec(r'/login/facebook', FacebookLoginHandler, name='login_facebook'),
            tornado.web.URLSpec(r'/login/twitter', TwitterLoginHandler, name='login_twitter'),
            tornado.web.URLSpec(r'/logout', AuthLogoutHandler, name='logout'),
            #(r'/static/(.*)', tornado.web.StaticFileHandler,
            #                {'path': os.path.join(PRJ_ROOT, 'static')}),
        ]

        if not settings['db_uri'].startswith('mongodb://'):
            settings['db_connection'] = connect(settings['db_uri'])
        else:
            #_tmp_db = settings['db_uri'][10:]
            #_tmp_db_name = _tmp_db.split('/')[1]
            #host="localhost", port=27017
            #settings['db_connection'] = connect(_tmp_db_name, host="localhost", port=27017)
            pass

        template_dirs = []
        jinja2_env = None

        if settings.get('template_path'):
            template_dirs.append(
                settings['template_path']
            )

        assets_env = AssetsEnvironment(settings['static_path'], '/')
        settings['jinja2_env'] = Jinja2Environment(loader=FileSystemLoader(template_dirs),
                                       extensions=[AssetsExtension])
        settings['jinja2_env'].assets_environment = assets_env

        tornado.web.Application.__init__(
            self,
            handlers,
            **settings
        )

def wsgi():
    """wsgi app creator"""
    return main(is_wsgi=True)

def main(is_wsgi=False):
    """This function runs web server"""
    tornado.options.parse_command_line()

    config = None

    try:
        with open(
            os.path.join(
                PRJ_ROOT,
                'config',
                options.version,
                __config__
                ),
            'r'
            ) as f:
            config = yaml.load(f)
        if 'settings' in config:
            pass
    except IOError:
        print('Invalid or missing config file: {}'.format(__config__))
    # if no settings, we go away
    except KeyError:
        print('No default configuration found')
        sys.exit(1)
    except Exception as ex:
        print('Smth unexpected happened')
        raise ex

    settings = config['settings']

    config['port'] = os.getenv('PORT', config['port'])

    settings['app_uri'] = os.getenv('APP_URI', settings['app_uri'])

    settings['static_path'] = os.path.join(PRJ_ROOT,
                                           settings['static_path'])
    settings['template_path'] = os.path.join(SRC_DIR,
                                             settings['template_path'])

    settings['twitter_consumer_key'] = os.getenv('TWITTER_APP_ID',
                                            settings['twitter_consumer_key'])
    settings['twitter_consumer_secret'] = os.getenv('TWITTER_SECRET',
                                            settings['twitter_consumer_secret'])

    settings['facebook_api_key'] = os.getenv('FACEBOOK_APP_ID',
                                            settings['facebook_api_key'])
    settings['facebook_secret'] = os.getenv('FACEBOOK_SECRET',
                                            settings['facebook_secret'])

    settings['google_oauth'] = settings.get('google_oauth', {})
    settings['google_oauth'] = {
                                'key': os.getenv('GOOGLE_APP_ID',
                                        settings['google_oauth'].get('key')),
                                'secret': os.getenv('GOOGLE_SECRET',
                                        settings['google_oauth'].get('secret'))
                                }

    settings['db_uri'] = os.getenv('MONGOLAB_URI', settings.get('db_uri', ''))

    for k, v in settings.items():
        if k.upper() in os.environ:
            settings[k] = os.getenv(k.upper(), v)
        elif k.endswith('_path'):
            settings[k] = v.replace(
                '__path__',
                PRJ_ROOT
            )

    application = App(settings)
    if is_wsgi:
        return tornado.wsgi.WSGIAdapter(application)

    http_server = tornado.httpserver.HTTPServer(application)
    http_server.listen(config['port'])

    if 'debug' in settings and settings['debug'] is True:
        #tornado.autoreload.watch(SRC_DIR)
        tornado.autoreload.watch(os.path.join(
                PRJ_ROOT,
                'config',
                options.version,
                __config__
                ))
        tornado.autoreload.watch(settings['template_path'])
        tornado.autoreload.watch(settings['static_path'])
        #tornado.autoreload.start(tornado.ioloop.IOLoop.instance())
        tornado.autoreload.start()

    tornado.ioloop.IOLoop.configure('tornado.platform.asyncio.AsyncIOLoop')

    try:
        tornado.ioloop.IOLoop.instance().start()
    except KeyboardInterrupt:
        sys.exit(0)

    #from tornado.platform.asyncio import AsyncIOMainLoop
    #import asyncio
    #AsyncIOMainLoop().install()
    #asyncio.get_event_loop().run_forever()

if __name__ == '__main__':
    main()

redpajama_set_name: RedPajamaGithub