text:
package de.cosmocode.palava.ipc;

import java.io.Serializable;
import java.util.Collection;
import java.util.Date;
import java.util.Map;
import java.util.Set;
import java.util.concurrent.TimeUnit;

import com.google.common.base.Preconditions;

import de.cosmocode.collections.callback.Callback;
import de.cosmocode.collections.callback.Callbacks;
import de.cosmocode.palava.scope.AbstractScopeContext;

/**
 * Abstract implementation of the {@link IpcSession} interface.
 *
 * @author Willi Schoenborn
 */
public abstract class AbstractIpcSession extends AbstractScopeContext implements IpcSession, Serializable {

    private static final long serialVersionUID = 6438707896566787757L;

    private long timeout;

    private TimeUnit timeoutUnit;

    private Date startedAt = new Date();

    private long lastAccess = System.currentTimeMillis();

    private boolean suppressingTouch;

    /**
     * {@link Callback} implementation used to handle updates in collection views.
     *
     * @since 2.0
     * @author Willi Schoenborn
     */
    private final class Toucher implements Callback {

        @Override
        public void poke() {
            touch();
        }

    }

    protected void setSuppressingTouch(boolean suppressingTouch) {
        this.suppressingTouch = suppressingTouch;
    }

    protected void setLastAccess(Date lastAccess) {
        this.lastAccess = Preconditions.checkNotNull(lastAccess, "LastAccess").getTime();
    }

    @Override
    public long getTimeout(TimeUnit unit) {
        Preconditions.checkNotNull(unit, "Unit");
        return unit.convert(timeout, timeoutUnit);
    }

    @Override
    public Date lastAccessTime() {
        return new Date(lastAccess);
    }

    @Override
    public void setTimeout(long time, TimeUnit unit) {
        Preconditions.checkNotNull(unit, "Unit");
        this.timeout = time;
        this.timeoutUnit = unit;
    }

    @Override
    public Date startedAt() {
        return startedAt;
    }

    public void setStartedAt(Date startedAt) {
        this.startedAt = Preconditions.checkNotNull(startedAt, "startedAt");
    }

    @Override
    public void touch() {
        if (suppressingTouch) return;
        this.lastAccess = System.currentTimeMillis();
    }

    @Override
    public boolean isExpired() {
        if (timeout == 0 || timeoutUnit == null) {
            return false;
        } else {
            return System.currentTimeMillis() - lastAccess > timeoutUnit.toMillis(timeout);
        }
    }

    @Override
    public Object putIfAbsent(Object key, Object value) {
        touch();
        return super.putIfAbsent(key, value);
    }

    @Override
    public boolean remove(Object key, Object value) {
        touch();
        return super.remove(key, value);
    }

    @Override
    public Object replace(Object key, Object value) {
        touch();
        return super.replace(key, value);
    }

    @Override
    public boolean replace(Object key, Object oldValue, Object newValue) {
        touch();
        return super.replace(key, oldValue, newValue);
    }

    @Override
    public int size() {
        touch();
        return super.size();
    }

    @Override
    public boolean isEmpty() {
        touch();
        return super.isEmpty();
    }

    @Override
    public Object remove(Object object) {
        touch();
        return super.remove(object);
    }

    @Override
    public void clear() {
        touch();
        super.clear();
    }

    @Override
    public boolean containsKey(Object key) {
        touch();
        return super.containsKey(key);
    }

    @Override
    public boolean containsValue(Object value) {
        touch();
        return super.containsValue(value);
    }

    @Override
    public Object get(Object key) {
        touch();
        return super.get(key);
    }

    @Override
    public Object put(Object key, Object value) {
        touch();
        return super.put(key, value);
    }

    @Override
    public void putAll(Map<? extends Object, ? extends Object> map) {
        touch();
        super.putAll(map);
    }

    @Override
    public Set<Object> keySet() {
        touch();
        return Callbacks.compose(super.keySet(), new Toucher());
    }

    @Override
    public Collection<Object> values() {
        touch();
        return Callbacks.compose(super.values(), new Toucher());
    }

    @Override
    public Set<Entry<Object, Object>> entrySet() {
        touch();
        return Callbacks.compose(super.entrySet(), new Toucher());
    }

}


I am proud to announce our 2nd WordPress Theme. Mag Style is a basic theme which uses no images. It would be perfect for an online magazine site, blog or news site.
The original design for this theme was done by Small Potato though all the coding was done by my associate Sarah Anderson.
We originally added lots of features like popular posts, featured articles etc, images etc; however we removed all of these as we didn't want to complicate matters. You see, the problem with adding more features, is that you sometimes add features that others don't need. You also run a higher risk of clashing with other WordPress plugins because you are calling many of the functions they use. Therefore, we decided to keep the theme as simple as possible so that users could customise the design the way they wanted.
You can see the theme in action on our demo blog.
Left and right sidebar on home page and category pages.
All of our themes are released free under the GNU General Public License.
See Mag Style in action!
I'd love to see some examples of the theme being used on the web, particularly from those who have made some modifications.
Just download the file listed below and upload the theme folder in your wp-content/themes directory. Then simply activate the theme in your admin area.
Just like all WordPress themes, to use it all you need to do is download the zip file, extract the files, upload the VideoTheme folder to your blogs wp-content/themes/ folder, and then activate the theme.
Mag Style comes with it's own theme options page (which can be found in the appearance section of the WordPress admin area).
In the options area you can add your feedburner and Twitter information. This will update the subscription box at the top of the sidebar.
Within the options area you can also add a 468×60 banner. All you need to do is upload your banner to the theme header folder, select the banner from the drop down list and then add your link underneath it.
The theme also has it's own basic contact form built in. All you need to do is go to your theme options page and enter your email address, your thank you page URL and the email subject for emails sent via the form.
Then you just need to create a contact page and select the contact template for the form to be placed within the page.
The theme comes with it's own Blogroll template. To display your blogroll on a page simply make sure that the page is using the blogroll.php template.
The sidebar.php and footer.php templates are both widget ready. Once you add a widget to these zones the dummy information will be removed. Details of how to remove the dummy information is contained in the theme ReadMe.txt file (the dummy info shows contains fake links and images etc to show what can be achieved with the theme).
I just don't have the time to offer personal email support. However, I encourage you to post any problems or questions you have in the WP Mods Forum. I'll do my best to help you as soon as I can. This also allows other users to contribute to the discussion.
As always, I'd love to know what you think of the theme. I'm sure that many of you will find it useful.
You cna download the theme here.
I do not get any download link.
Please send me the link….
Hi there, I subscribed to your newsletter and wanted to download the theme, but I could not see any link. I'm interested in the theme and would love to get my hands on it.
Could you please let me know what the download link is or email me the details.


text:
"""
Description:

There is a queue for the self-checkout tills at the supermarket. Your task is write a function to calculate the total time required for all the customers to check out!

The function has two input variables:

customers: an array (list in python) of positive integers representing the queue. Each integer represents a customer, and its value is the amount of time they require to check out.
n: a positive integer, the number of checkout tills.
The function should return an integer, the total time required.

EDIT: A lot of people have been confused in the comments. To try to prevent any more confusion:

There is only ONE queue, and
The order of the queue NEVER changes, and
Assume that the front person in the queue (i.e. the first element in the array/list) proceeds to a till as soon as it becomes free.
The diagram on the wiki page I linked to at the bottom of the description may be useful.
So, for example:

queue_time([5,3,4], 1)
# should return 12
# because when n=1, the total time is just the sum of the times

queue_time([10,2,3,3], 2)
# should return 10
# because here n=2 and the 2nd, 3rd, and 4th people in the
# queue finish before the 1st person has finished.

queue_time([2,3,10], 2)
# should return 12
N.B. You should assume that all the test input will be valid, as specified above.

P.S. The situation in this kata can be likened to the more-computer-science-related idea of a thread pool, with relation to running multiple processes at the same time: https://en.wikipedia.org/wiki/Thread_pool
"""

from collections import deque

def queue_time(customers, n):
    sum = 0
    line = deque(customers)
    tills = []
    while line or len(tills):
        while len(tills) < n and line:
            tills.append(line.popleft())
        tills.sort(reverse=True)
        sum += tills[-1]
        tills = [x - tills[-1] for x in tills if x - tills[-1] > 0]
    return sum

"""
BEST ANSWER:

def queue_time(customers, n):
    l=[0]*n
    for i in customers:
        l[l.index(min(l))]+=i
    return max(l)
"""

redpajama_set_name: RedPajamaGithub


text:
Home / Rare Movies / The Sword and the Sorcerer (1982) Dvd
The Sword and the Sorcerer (1982) Dvd
The Sword and the Sorcerer (1982) Dvd quantity
SKU: 4818 Categories: Adventure and Fantasy, Rare Movies
Actors: Lee Horsley, Kathleen Beller
Run Time: 99mins
Plot: A mercenary with a three-bladed sword rediscovers his royal heritage's dangerous future when he is recruited to help a princess foil the designs of a brutal tyrant and a powerful sorcerer in conquering a land.
We supply rare movie titles that were never available on DVD through retailers here in the U.S. and out-of-print movie titles that are no longer available through retailers. All our DVD titles are suitable and playable worldwide for all regions.
Be the first to review "The Sword and the Sorcerer (1982) Dvd" Cancel reply
The Fortune Jack Nicholson, Warren Beatty Dvd
Mortal Sins Dvd
Countess Dracula Remastered Dvd
Night of the Running Man

redpajama_set_name: RedPajamaCommonCrawl


»I come from a small village of Šentjošt. For generations we have been cooking over the fire. My grandmother prepared food on a stove. When I think of flames, they always take me back to my childhood, into her kitchen.


Look through the profiles of Member members that have joined Online Chat City that are associated with Music lover. Talking to others who have like minded interests is an ideal way to find things to do on a first date. Signup for a Free Profile to Go out Today!
simple. classique. ambiance. friends .


Years of Experience in Logistics transformed our view of the goods in a very critic one when it comes to evaluating the conditions of the products we process.
Wrinkled clothes, missing buttons, out of shape footwear… All these small issues that might affect the decision of the final buyer.
TML takes care about all of these issues by offering a reconditioning service. By returning to the processed goods their original freshness and shape, fitting the exposition in the boutique.
We also can provide an Ironing service thanks to our partner whom has been working with us for years. They can provide a professional service thanks to their advanced machinery and techniques, and their experience in this sector of over 20 years.
Many years of collaboration with many famous fashion brands are the source of our knowledge in this industry. We learned the value of providing a full-fledged service. Attention to detail, dedication and the outmost care in processing the goods. Thanks to the help of our experienced partner, we can provide a complete reconditioning and ironing service.
We manufacture on demand wooden crates and cages. On request the building materials can undergo fumigation.
Fixed costs are now flexible. Discover the advantage of having a reliable logistic partner at your service. It is our company policy to provide differentiated rates, we believe that every customer is different and has different needs.
We manage all the returning goods as for our protocol, developed to handle and simplify reverse logistics procedures for our clients.
We use thermoforming machines to detect any tampering of small and medium packages.
Our fashion branch is equipped with appliances so to guarantee exclusive and scrupulous clothes reconditioning services.
We offer our strategical and technical support to improve your new e-commerce activity or follow you through the first steps of your startup.
La reputazione di un'azienda si costruisce attraverso l'immagine che essa è in grado di proporre e difendere, e l'immagine aziendale è, a sua volta, legata a doppio filo a quella dei prodotti dell'azienda stessa.
Questo significa che un prodotto mal presentato (un capo stropicciato, un accessorio difettoso) non solo rischia di contrariare un potenziale acquirente, ma anche di andare a detrimento della brand reputation dell'azienda che lo commercializza.


text:
https://www.sfgate.com/bayarea/article/Cyclists-app-aids-traffic-planners-3280978.php
Cyclists' app aids traffic planners
City insider
Michael Cabanatuan, Heather Knight
Published 4:00 am PST, Tuesday, November 17, 2009
If you see bicyclists wobbling through the city streets with an iPhone in hand, don't assume they're playing Bejeweled or IMing their virtual pals while they pedal.
They may be using Cycle Tracks, the San Francisco County Transportation Authority's new - and first - application for the Apple iPhone.
Once bike riders install the app, they tap the "start recording" button, which begins tracking their trips and displaying them on a city map. When they're done pedaling, they hit the "save" button, and the details of their journeys are sent to the authority, as well as saved in the user's iPhone. The app uses GPS to track riders' routes.
The authority plans to feed the data into the state-of-the-art computer model it uses to predict future traffic patterns. The goal is to figure out where bicyclists ride, why they choose those routes and how development decisions or transportation changes might affect them, said Billy Charlton, the authority's deputy director for technology services.
As an incentive to get more cyclists to download and use Cycle Tracks, the authority is holding a drawing for 10 $50 iTunes gift cards. Anyone who downloads the app and uses it at least once will automatically be entered.
For those secretive (or paranoid) cyclists who want to help out but might not want certain trips tracked, the authority offers some assurances. All trips are dumped into the database anonymously, they say, and someone who ends up pedaling somewhere they don't want anyone to know about can always hit the cancel button, and the evidence will be erased.
- Michael Cabanatuan
One of a kind: Forget that last-minute, blood-pressure-spiking run to Stonestown, or even Black Friday, for that matter. The city's Arts Commission is pushing a different idea when it comes to holiday shopping: purchasing unique artwork from the city's more than 430 licensed street artists.
They're the ones with booths at Justin Herman Plaza, Union Square, Fisherman's Wharf and elsewhere selling their jewelry, paintings, photography, glassware and much more. And the arts commission is waging a public awareness campaign to get shoppers to give them a second glance.
Luis Cancel, director of cultural affairs for San Francisco, said it pays off for the shopper, the artist and the city.
"By supporting these independent street artists, consumers are indirectly pumping an estimated $4 million annually into San Francisco's economy," he said.
Howard Lazar, director of the city's Street Artists Program, said wearable art - including jewelry, clothing and crocheted hats - are the most marketable, while photography, plates and paintings are also popular.
"When you shop at a street artist's booth, you get much more than a piece of jewelry or a scarf," he said. "You get a completely unique San Francisco experience."
The Arts Commission is producing a show about street artists to air on SFGTV and on its Web site in December.
- Heather Knight


Looking to value, trade, or sell your equipment?
We a brokerage firm that advertises and sells piling and drilling equipment for private owners, banks, and equipment dealers worldwide. We are one of the industry's leading suppliers of used and repossessed equipment.


Welcome to the 3rd week of the Blogmas link party extravaganza and giveaway!
Welcome to the Recipe Party!!
Glad you asked! Blogmas is a 4 week blog event, created by Chelc at Inside the Fox Den and Amanda at The Kolb Corner! Starting today and going until December 26th, we will have a link up every Saturday dedicated to a specific theme; décor, gifts, recipe, and lifestyle. With the holidays fast approaching, we wanted to have an outlet for us, and you, to share your festive creativity and get some awesome inspiration! We'll also be giving away a gift basket filled with goodies hand selected by the hosts!
You all absolutely blew us away with your creative gift ideas! Here are some of our favorites!
Love getting my snowmen collection out.
My favorite part of decorating for Christmas this year has been hanging the stockings, because I have a fireplace now!


text:
Philonome clemensella is a species of moth of the  family Tineidae found in North America.

Description
The length of the forewings is 2.8–4.4 mm. The wings are narrow and typically folded around the abdomen at rest. The forewing has an orange-brown ground color. A diagonal, white median line stops short of the costa and turns parallel to the costa to meet the white thorax. A diagonal, white postmedial line begins wide at the costa and narrows and stops before reaching the curved outer margin. Black scales appear in several small clumps: posterior to the thorax, in a tuft near the median line, at the inner end of the postmedial line, and along the outer margin.

Taxonomy
The species has been classified in the leaf-miner moth family Lyonetiidae in the past. A genetics study published in 2013 showed that the species belongs in the family Tineidae of clothes moths.

Range
The species' occurrence range extends from Oklahoma and Minnesota in the west to Florida and Maine in the east, including southeastern Canada.

Life cycle
Previous accounts have reported that P. clemensella have been collected from hickory and linden trees, however recent review indicates: "these were based on the ambiguous label data of specimens from the United States National Museum of Natural History. No additional observation of the larvae of P. clemensella has been reported from these trees." Adults have been reported from April to November, with most sightings in June and July.

References

Moths described in 1874
Tineidae

redpajama_set_name: RedPajamaWikipedia


text:
Longevity Medicine Review Analyzing the latest research in longevity science
Beyond the Mitochondrial Tune Up: Part II
By Lara Pizzorno on July 20, 2018 in Anti-aging, Mitochondria
Part II: The Methylation – Transsulfuration Connection to Mitochond
Mitochondrial decay resulting from oxidative damage accumulates with age and is universally recognized as a major contributing factor to the whole range of functional decline and tissue deterioration associated with aging.1 2 3 4 5 6 7 Part I of this review discussed Bruce Ames' application of the Michaelis constant (KM) concept to the ramifications of age-associated oxidative damage to proteins. Specifically, with age, increased oxidative damage to key enzymes produces deformation in their structure, resulting in an increased Michaelis constant (KM), i.e., a decreased binding affinity for the co-enzyme (the nutrient co-factor for the enzyme), thus causing a decrease in enzyme function.8 Ames' research has demonstrated that increasing the availability of acetyl L-carnitine, the substrate for the enzyme acetyl-L-carnitine transferase, (which plays a key role in transporting long-chain fatty acids into the mitochondria for β oxidation and ATP production), along with α-lipoic acid, (a mitochondrial antioxidant that also serves as cofactor for two key enzymes in the Krebs cycle, pyruvate dehydrogenase and α-ketoglutarate dehydrogenase), restores the velocity of the reactions (KM) for these enzymes, and thus restores aging mitochondria's ability to regain youthful levels of energy production.9 10 11 12 13
Single Nucleotide Polymorphisms plus KM equals Double Jeopardy
In addition to the aging-associated accumulation of oxidative damage, single nucleotide polymorphisms (SNPs) are another factor affecting KM, and one that, since the activity of the enzymes affected is down-regulated from birth, may promote premature aging. As many as one-third of all mutations in a gene result in the corresponding enzyme having an increased KM (decreased binding affinity) for a coenzyme, and therefore a lower rate of reaction.
One well-researched and pivotal example in terms of its impact on mitochondrial function is the 677CàT SNP of methylenetetrahydrofolate reductase (MTHFR), a key enzyme in the methylation cycle. MTHFR is responsible for the conversion of folic acid into methionine synthase, which, along with B12, recycles homocysteine to methionine.
In the fairly common 677CàT variant (~30-40% incidence), thymine is substituted for cytosine in the gene, resulting in production of a slow variant of the MTHFR enzyme in which valine is substituted for alanine at position 222 (for which reason this SNP is also labeled Ala222Val). In individuals in whom both alleles have this SNP (i.e., individuals homozygous for the TT genotype of MTHFR, (~10% of the North American population14), the resulting enzyme expressed has only 50% of the activity of the wild (more common) CC type.15
Similar to the way in which providing supplemental acetyl-L-carnitine restores the KM for acetyl-L-carnitine transferase, providing supplemental folate, the substrate for MTHFR, may help compensate for the drop in MTHFR activity that will otherwise occur in carriers of this SNP. Another way of looking at this is that carriers of the MTHFR 677CàT SNP have an increased requirement for folate to optimize the activity of this enzyme, and thus require more folate for normal methylation.
Whether impaired MTHFR activity is the result of age-associated oxidative damage or genetic inheritance, restoring normal levels of MTHFR activity is essential for optimal function in aging mitochondria. When MTHFR is compromised, not only is methylation impaired, but unmetabolized homocysteine accumulates in the cell and effluxes into the bloodstream. In both, homocysteine will react with reactive oxygen intermediates, greatly increasing the rate of antioxidant consumption, including that of GSH, an antioxidant critical for neutralizing mitochondrial reactive oxygen species (ROS).
High levels of homocysteine have been shown to increase ROS and lipid peroxidation in the endothelium, liver, kidney and brain.16 17 18 19 In addition to decreasing antioxidant defenses and total thiol content (Thiols are compounds that contain the functional group [–SH], aka a sulfhydryl or thiol group. [–SH] is the sulfur analogue of an alcohol group [–OH]. Key compounds in mitochondrial energy production, coenzyme A, cysteine, GSH, and α-lipoic acid are all thiols), hyperhomocystenemia has been shown to disrupt the activity of all three key mitochondrial antioxidant enzymes (superoxide dismutase [which neutralizes superoxide radical (O2−)], catalase [which neutralizes hydrogen peroxide (H2O2)] and glutathione peroxidase (GPx) [which reduces H2O2 and lipid peroxides]).17
Homocysteine Metabolism – Linking Methylation, Transsulfuration and Mitochondrial Function
Decreased MTHFR activity hamstrings the methylation cycle, resulting in increasing levels of homocysteine, increased ROS production, decreased S-adenosylmethionine (SAM) production, and increased oxidative stress, which greatly increases the rate of glutathione (GSH) depletion.
In addition to its role in the methylation cycle, homocysteine is involved in transsulfuration as the precursor to cysteine, the rate-limiting factor for the production of GSH, the premier endogenous antioxidant. Thus homocysteine serves as an essential factor in the body's major antioxidant system—when other processes utilizing homocysteine, i.e., methylation, are functioning normally. However, when the interactive balance among these pathways is compromised, alteration in the level any of the thiols affects the others.20
Compromised methylation results in increased homocysteine efflux into plasma, where it is highly susceptible to being oxidized, increasing the formation of superoxide radical (O2−) and hydrogen peroxide (H2O2), thus increasing systemic demand for GSH. When methylation is chronically compromised (as in an individual homozygous for the 677CàT SNP or one with insufficient intake of nutrient co-factors essential for the activity of enzymes involved in methylation, e.g., vitamins B6, B12, folate and riboflavin), plasma levels of homocysteine are chronically elevated, resulting in chronically increased need for GSH. In turn, low GSH concentrations dramatically accelerate homocysteine oxidation, perpetuating the vicious cycle.20
Clinical and epidemiological evidence suggests that a plasma level of homocysteine >15 μmol/l, although only modestly elevated, is associated with vascular disease, a finding that may be linked to homocysteine's effects on thiol balance. In recent years, several studies have shown that moderate hyperhomocysteinemia is associated with premature cerebrovascular, peripheral and coronary artery disease.20 Disruption of the interactive balance among the roles played by thiols, resulting in GSH depletion and mitochondrial dysfunction, may prove to be an underlying factor as important as high cholesterol.
The effects of thiol disequilibrium have also been noted in a recent study of autistic children. In these children, the ratio of plasma S-adenosylmethionine (SAMe) to S-adenosylhomocysteine (SAH) was significantly reduced; the mean concentration of reduced GSH, the major intracellular antioxidant and mechanism for detoxification, was significantly decreased; and the oxidized disulfide form of GSH (GSSG) was significantly increased, resulting in a 2-fold reduction in the mean GSH:GSSG redox ratio. Several metabolic precursors for GSH synthesis were found to be lower in autistic children, suggesting insufficient GSH synthesis. These combined findings indicate a significant decrease in methylation capacity (↓SAM:SAH), resulting in a decrease in antioxidant/detoxification capacity (↓GSH:GSSG) and an increase in oxidative stress (↑GSSG) in autistic children.21
In this study, 40 autistic children were treated with 75 µg/kg methylcobalamin (2 times/week) and 400 µg folinic acid (2 times/day) for 3 months.
While the intervention did not alter methionine, SAM, and SAH concentrations significantly (despite the fact that methylcobalamin and folinic acid provide methyl groups for the methylation cycle), concentrations of the transsulfuration metabolites, cysteine, cysteinylglycine, and GSH, increased significantly, and oxidized GSSG levels were reduced to the point that after the intervention, these metabolites were no longer statistically different compared to those in healthy control children. Measures of autistic behavior were assessed by a trained study nurse pre- and post-treatment using the Vineland Adaptive Behavior Scales, and significant improvement was observed after treatment, although scores remained below normal.
The finding that plasma concentrations of methionine and SAM were unaffected (and remained significantly below those in the control subjects) was unexpected because methylcobalamin and folinic acid directly provide methyl groups for synthesis of methionine and SAM, and only secondarily provide metabolic precursors for transsulfuration reactions.
The explanation appears to lie in the fact that the enzymes within the methylation cycle, (methionine synthase, betaine-homocysteine methyltransferase, and methionine adenosyltransferase) are redox-sensitive and are down-regulated by oxidative stress. Under pro-oxidant conditions, this serves to promote preferential utilization of homocysteine for GSH synthesis at the expense of methylation.
Similarly, in addition, cystathionine beta synthase (CBS) contains a heme component, which serves as a redox sensor that upregulates CBS activity under oxidative conditions. This adaptive up-regulation of CBS activity further promotes cysteine and GSH synthesis by irreversibly diverting homocysteine away from methionine remethylation and down the transsulfuration pathway.
Short term, the response of these enzymes to oxidative stress is protective, allocating metabolic resources to quickly restore GSH concentrations and maintain intracellular redox status in response to oxidative challenge.
Chronically compromised methylation, however, leads to increased plasma homocysteine levels, promoting chronic oxidative stress. In a state of chronic oxidative stress, synthesis of methionine and its product, SAM, progressively decline with a key factor being oxidative inactivation of the cobalamin cofactor of methionine synthase. In this way, unresolved oxidative stress can promote precursor depletion and a progressive decrease in cysteine and GSH synthesis.
Ames' KM concept provides an explanation for the positive outcome in this study of children with autism, a condition characterized by unremitting oxidative stress. By restoring enzyme activity, treatment with methylcobalamin and folinic acid lowers homocysteine and rescues GSH synthesis.
The Methylation – Transsulfuration Connection to Mitochondrial Decay
As noted in Part I of this review, GSH is the body's most critical intracellular antioxidant and a key conjugating agent in Phase II detoxification. High levels of homocysteine, which lead to chronic oxidative stress and GSH depletion, gravely impact not only mitochondrial function, but that of every cell and system in the body.
Following the logic chain outlined in this article, it is not surprising that folate insufficiency, and the resultant increase in homocysteine levels, which, if chronic, can lead to a decrease in SAM and GSH, has also recently been recognized to be a significant risk factor for Alzheimer's disease and other dementias, and is strongly associated with depression, with approximately one-third of depressed individuals having frank folate deficiency.15 22 SAM is a key donor of methyl groups, which are necessary for the formation of neurotransmitters (e.g., serotonin) and phospholipids that are a component of neuronal myelin sheaths, and cell receptors.23
{image_1}
Methylation pathway: (1)Methionine is converted by methionine adenosyltransferase into the methyl donor S-adenosylmethionine (SAM), which is acted upon by methyltransferase and gives up a methyl group, becoming S-adenosyl homocysteine (SAH). SAH hydrolase converts SAH to homocysteine. (2)Homocysteine can either be remethylated through the folate cycle or go down the transsulfuration pathway. (3) The folate cycle requires the enzyme 5,10-methylenetetrahydrofolate reductase (MTHFR) and folic acid (which enters the cycle as tetrahydrofolate [THF]), plus the enzyme methionine synthase (MS) and vitamin B12, which is the cofactor [in the form of methylcobalamin] for methionine synthase and uses the substrates 5-methyl-tetrahydrofolate and homocysteine. (4) In liver and kidney, homocysteine is also remethylated by the enzyme betaine homocysteine methyltransferase (BHMT), which transfers a methyl group to homocysteine via demethylation of betaine to dimethylglycine (DMG).
Transsulfuration pathway: (1)Homocysteine is converted to cystathionine by the enzyme cystathionine beta-synthase (CBS), which requires the cofactor vitamin B6 (pyridoxyl phosphate). Once formed from cystathionine via the action of cystathionine gamma-lyase, cysteine can be utilized in a number of cellular functions, including glutathione (GSH) production and protein synthesis.
Methylation / Transsulfuration / Homocysteine Connection to GSH Depletion: When methylation is compromised, plasma homocysteine levels rise, increasing oxidative stress and the rate at which glutathione stores are depleted. When homocysteine elevation is chronic, redox sensitive enzymes in the methylation cycle (methionine synthase and the methyl transferase enzymes, betaine-homocysteine methyltransferase and methionine adenosyltransferase) are down-regulated, which promotes preferential utilization of homocysteine for GSH synthesis at the expense of methylation. In addition, cystathionine beta synthase (CBS) contains a heme component that is thought to serve as a redox sensor that upregulates CBS activity under oxidative conditions. This adaptive up-regulation of CBS activity promotes cysteine and GSH synthesis by irreversibly diverting homocysteine away from methionine remethylation and down the transsulfuration pathway. Short term, this serves as a protective mechanism, quickly restoring GSH concentrations to maintain intracellular redox status during oxidative stress.Chronically compromised methylation, however, leads to increased homocysteine levels and chronic oxidative stress. This results in oxidative inactivation of the cobalamin cofactor of methionine synthase causing progressive decline in synthesis of methionine and SAM, which ultimately promotes precursor depletion and a progressive decrease in cysteine and GSH synthesis.
Optimal Nutrition for Mitochondrial Function
While it has commonly been thought that Americans' intake of essential micronutrients is adequate, evidence indicates that damage occurs at nutrient levels higher than those known to cause acute deficiency disease and, in some individuals (e.g., those with SNPs resulting in lessened KM), it is obvious that higher than DRI levels of the associated enzyme co-factors are necessary for optimal function.
In addition to folate, MTHFR contains a bound flavin cofactor (derived from riboflavin, which as noted in Part I is a nutrient cofactor also required in the Krebs cycle and electron transport chain) and uses NADPH (which requires niacin as its co-factor and also plays a central role in mitochondrial oxidative phosphorylation) as the reducing agent. SNPs resulting in an increased need for both riboflavin and niacin have also been identified.
The key clinical take-away, first proposed by Bruce Ames in his seminal paper on SNPs, decreased coenzyme binding affinity, and related nutrient needs, and recently re-emphasized by leading nutrigenomics researcher Michael Fenech, is that the activity of the reaction catalyzed by the MTHFR gene—and therefore the risks associated with the lessened MTHFR activity seen in carriers of 677CàT—can be markedly modified by the providing higher than "average" amounts of not just folate, the substrate for MTHFR, but also riboflavin and niacin, its cofactors.25 8
Basic biochemistry and other studies suggest that not only higher than DRI amounts of riboflavin and niacin, but of vitamin B6, cobalamin (vitamin B12) and choline, may also be needed to optimize MTHFR-related methylation capacity in carriers of MTHFR SNPs. Homocysteine is metabolized through three vitamin B–dependent pathways. It can be either (1) remethylated and recycled as methionine, a reaction catalyzed by either the enzyme betaine homocysteine methyltransferase (in which the co-factor betaine is derived from choline) or (2) by the vitamin B12-dependent enzyme methionine synthase, or (3) homocysteine can be removed from the remethylation cycle by undergoing irreversible B6-dependent transsulfuration via the enzyme cystathionine beta synthase to form cysteine.26 27
The folate, methylation and transsulfuration pathways are not separate entities but comprise an interconnected cellular network whose disruption, at any point, may have far-reaching deleterious effects, one of which is increased free radical production coupled with disruption of glutathione (GSH) production—a surefire recipe for accelerated mitochondrial decay and aging.
Ensuring adequacy of all the nutrient co-factors necessary to restore KM in all these pathways, as well as for mitochondrial oxidative phosphorylation (discussed in Part I of this review), is first line therapy for promoting healthy aging. However, a protocol whose end goal is restoration of KM, while certainly helpful in delaying mitochondrial decay, does not address a more fundamental issue – why does human physiology shift from a homeostasic state that repairs and balances itself to one that allows decay to accumulate? Researcher Wulf Dröge has called this shift "the first cause of death," and his insights into its likely causes may provide the means to opt out of the vicious cycle responsible for the age-associated move from a state of youthful homeostatic repair to a one that promotes mitochondrial decay. This will be the topic of Part III of this review: Reversing the Age-related Metabolic Shift towards Mitochondrial Decay.
Read Part I: Delaying the Mitochondrial Decay of Aging
Read Part III: Restoring Mitophagy – the Key To Mitochondrial Rejuvenation
Harman D. Free radical theory of aging: history. EXS. 1992;62:1-10. ↑
Wei YH, Lu CY, Lee HC, et al. Oxidative damage and mutation to mitochondrial DNA and age-dependent decline of mitochondrial respiratory function. Ann N Y Acad Sci. 1998 Nov 20;854:155-70. ↑
Lenaz G. Role of mitochondria in oxidative stress and ageing. Biochim Biophys Acta. 1998 Aug 10;1366(1-2):53-67. ↑
Shigenaga MK, Hagen TM, Ames BN. Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci U S A. 1994 Nov 8;91(23):10771-8. ↑
Beckman KB, Ames BN. The free radical theory of aging matures. Physiol Rev. 1998 Apr;78(2):547-81. ↑
Wei YH, Ma YS, Lee HC, Lee CF, Lu CY. Mitochondrial theory of aging matures–roles of mtDNA mutation and oxidative stress in human aging. Zhonghua Yi Xue Za Zhi (Taipei). 2001 May;64(5):259-70. ↑
Gruber J, Schaffer S, Halliwell B. The mitochondrial free radical theory of ageing–where do we stand?. Front Biosci. 2008 May 1;13:6554-79. ↑
Ames BN, Elson-Schwab I, Silver EA. High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms. Am J Clin Nutr. 2002 Apr;75(4):616-58. ↑
Hagen TM, Yowe DL, Bartholomew JC, et al. Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase. Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3064-9. ↑
Hagen TM, Liu J, Lykkesfeldt J, et al. Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1870-5. ↑
Liu J, Head E, Gharib AM, et al. Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-α-lipoic acid. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):2356-61. ↑
Liu J, Killilea D, Ames BN. Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-α-lipoic acid. Proc Natl Acad Sci U S A. 2002 Feb 19;99(4):1876-81. ↑
Hagen TM, Moreau R, Suh JH, et al. Mitochondrial decay in the aging rat heart: Evidence for improvement by dietary supplementation with acetyl-L-carnitine and/or lipoic acid. Ann N Y Acad Sci. 2002 Apr;959:491-507. ↑
Schneider JA, Rees DC, Liu YT, Clegg JB (May 1998). Worldwide distribution of a common methylenetetrahydrofolate reductase mutation. Am. J. Hum. Genet. 62 (5): 1258–60. ↑
Pizzorno LE, Nutrigenomics – the potential to optimize phenotpye with SNP-based dietary recommendations. IMCJ in press for the Sept 2009 issue. ↑
Matté C, Stefanello FM, Mackedanz V, et al. This is where the problem text should be. Int J Dev Neurosci. 2009 Jun;27(4):337-44. ↑
Matté C, Mackedanz V, Stefanello FM, et al. Chronic hyperhomocysteinemia alters antioxidant defenses and increases DNA damage in brain and blood of rats: protective effect of folic acid. Neurochem Int. 2009 Jan;54(1):7-13. ↑
Bleich S, Spilker K, Kurth C, et al. Oxidative stress and an altered methionine metabolism in alcoholism. Neurosci Lett. 2000 Nov 3;293(3):171-4. ↑
Atamer A, Kocyigit Y, Ecder SA, et al. Effect of oxidative stress on antioxidant enzyme activities, homocysteine and lipoproteins in chronic kidney disease. J Nephrol. 2008 Nov-Dec;21(6):924-30. ↑
Ozkan Y, Ozkan E, Simşek B. Plasma total homocysteine and cysteine levels as cardiovascular risk factors in coronary heart disease. Int J Cardiol. 2002 Mar;82(3):269-77. ↑
James SJ, Melnyk S, Fuchs G, et al. Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. Am J Clin Nutr. 2009 Jan;89(1):425-30. ↑
Miller AL. The methylation, neurotransmitter, and antioxidant connections between folate and depression. Altern Med Rev. 2008 Sep;13(3):216-2. ↑
Karakuła H, Opolska A, Kowal A, et al. [Does diet affect our mood? The significance of folic acid and homocysteine]. Pol Merkur Lekarski. 2009 Feb;26(152):136-41. ↑
Austin RC, Lentz SR, Werstuck GH. Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease. Cell Death Differ. 2004 Jul;11 Suppl 1:S56-64. ↑
Thomas P, Fenech M. Methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease. Vitam Horm. 2008;79:375-92. ↑
Hustad S, Midttun Ø, Schneede J, et al. The methylenetetrahydrofolate reductase 677C–>T polymorphism as a modulator of a B vitamin network with major effects on homocysteine metabolism. Am J Hum Genet. 2007 May;80(5):846-55. ↑
Strain JJ, Dowey L, Ward M, Pentieva K, McNulty H. B-vitamins, homocysteine metabolism and CVD. Proc Nutr Soc. 2004 Nov;63(4):597-603. ↑
About Lara Pizzorno
Lara Pizzorno, MDiv, MA, LMT A member of the American Medical Writers Association with 25+ years of experience writing for physicians and the public, Lara is Editor of Longevity Medicine Review as well as Senior Medical Editor for SaluGenecists, Inc. Recent publications include: Your Bones (Praktikos, April 2011), contributing author to the Textbook of Functional Medicine, (IFM, 2006), articles for Integrative Medicine: A Clinician's Journal (Innovisions Communications, Inc., 2005 through present), and Textbook of Natural Medicine (Elsevier, 2005, e-dition through present); lead author of Natural Medicine Instructions for Patients (Elsevier, 2002); co-author of The Encyclopedia of Healing Foods (Scribner's, 2005); and editor, The World's Healthiest Foods Essential Guide for the healthiest way of eating (George Mateljan Foundation, 2006 through present). In addition to reviewing the latest in longevity research for clinicians, Lara summarizes health & nutrition research for the Textbook of Natural Medicine e-dition, The World's Healthiest Foods (www.whfoods.org), and Dr. Joseph Pizzorno's blog as WebMD's Integrative Medicine & Wellness Expert. Lara graduated Phi Beta Kappa, magna cum laude from Wheaton College (Norton, MA, 1970), received her Master's in Religious Studies with Honors from Yale Divinity School (New Haven, CT, 1973), Master's in Literature from the University of Washington (Seattle, 1986), and has been a licensed massage therapist since 1986. Avocations include Pilates, motorcycling, organic gardening, healthy cooking.
View all posts by Lara Pizzorno →
Beyond the Mitochondrial Tune Up: Part I
Beyond the Mitochondrial Tune Up: Part III
AGE's
Erectile Function
SNP's
Ensure Effective Bio-Identical Hormone Replacement: Select the Right Hormone Test for Your Patient
Bio-Identical Hormone Replacement: Selecting the Right Hormone Test(s) for Your Male Patient
Vitamin K2: Optimal Levels Essential for the Prevention of Age-Associated Chronic Disease
Calcium Supplements Increase Risk of MI—The "One Variable" Emperor is Naked
Resveratrol, Niacin, Nicotinamide Riboside: Key Players in Activating Sirtuins to Mimic Calorie Restriction & Extend Lifespan, Part I
Resveratrol, Niacin, Nicotinamide Riboside: Key Players in Activating Sirtuins to Mimic Calorie Restriction & Extend Lifespan, Part II
Alzheimer's and Atherosclerosis – Siblings in a Dysfunctional Family: Part I
Getting off the Alzheimer's Disease Interstate: Part II
Vitamin D and Vitamin K Team Up to Lower CVD Risk: Part I
Vitamin D and Vitamin K Team Up to Lower CVD Risk: Part II
Statements on this website have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
NutriCrafters LLC © 2013. All Rights Reserved.


TDL 1 (Stoneware), 1997, 12" x 54" x 14", ceramic.
TDL 3 (Milk of Vesuvius), 1997, 12" x 54" x 14", mixed media.
TDL 3 (Wax), 1997, 12" x 54" x 14", mixed media.
that transcends one's own clumsy, upright mobility..."
What you see #2 (of seven parts), 1998, 7" x 7" x 4", tempera on ceramic, private collection.
What you see (seven parts), 1998, 7" x 7" x 4", tempera on ceramic, private collection.
Click image to view virtual facsimile of the book.
Kim So-Jeong and Matthew Meyers.


text:
package kubesh

import (
	"fmt"
	"io"
	"os"
	"os/exec"
	"os/signal"
	"path"
	"strings"
	"syscall"
	"time"

	"github.com/bbrowning/readline"
	"github.com/spf13/cobra"

	"k8s.io/kubernetes/pkg/kubectl/cmd"
	cmdutil "k8s.io/kubernetes/pkg/kubectl/cmd/util"
	"k8s.io/kubernetes/pkg/util/homedir"
)

type kubesh struct {
	finder     ResourceFinder
	context    []string
	lineReader *readline.Instance
	progname   string
	factory    *cmdutil.Factory
	out        *NewlineEnsuringWriter
}

func NewKubesh() *kubesh {
	factory := cmdutil.NewFactory(nil)
	sh := kubesh{
		factory:  &factory,
		finder:   TimeoutFinder{Resourceful{&factory}, time.Second * 2},
		progname: os.Args[0],
		out:      &NewlineEnsuringWriter{delegate: os.Stdout},
	}
	completer := NewCompleter(sh.newRootCommand(), sh.finder, &sh.context)
	sh.lineReader, _ = readline.NewEx(&readline.Config{
		Prompt:       prompt([]string{}),
		AutoComplete: completer,
		HistoryFile:  path.Join(homedir.HomeDir(), ".kubesh_history"),
		Listener:     completer,
	})
	return &sh
}

func (sh *kubesh) Run() {
	defer sh.lineReader.Close()
	for {
		line, err := sh.lineReader.Readline()
		if err == readline.ErrInterrupt {
			if len(line) == 0 {
				break
			} else {
				continue
			}
		} else if err == io.EOF {
			break
		}
		args, err := tokenize(line)
		if err != nil {
			fmt.Println(err)
		} else if len(args) > 0 {
			cmd := sh.findCommand(args)
			// TODO: what do we do with an error here? do we care?
			args, _ = applyContext(sh.context, args, cmd)
			sh.runCommand(cmd, args)
		}
		// if the command output something w/o a trailing \n, it won't
		// show, so we make sure one exists
		sh.out.EnsureNewline()
	}
}

func (sh *kubesh) Execute(args []string) {
	cmd := sh.newRootCommand()
	cmd.SetArgs(args)
	cmd.Execute()
}

func (sh *kubesh) findCommand(args []string) Command {
	root := sh.newRootCommand()
	cmd, _, _ := root.Find(args)
	return KubectlCommand{cmd}
}

func (sh *kubesh) runCommand(cmd Command, args []string) {
	defer func() {
		// Ignore any panics from kubectl
		recover()
	}()
	switch cmd.Name() {
	case "proxy", "attach":
		sh.runExec(args)
	default:
		sh.Execute(args)
	}
}

func (sh *kubesh) runExec(args []string) {
	cmd := exec.Command(sh.progname, args...)
	cmd.Stdin = os.Stdin
	cmd.Stdout = os.Stdout
	cmd.Stderr = os.Stderr
	cmd.Start()

	signals := make(chan os.Signal, 1)
	signal.Notify(signals, syscall.SIGINT)
	defer signal.Stop(signals)
	go func() {
		<-signals
		fmt.Println("")
		syscall.Kill(cmd.Process.Pid, syscall.SIGINT)
	}()

	cmd.Wait()
}

func (sh *kubesh) newRootCommand() *cobra.Command {
	root := cmd.NewKubectlCommand(*sh.factory, os.Stdin, sh.out, os.Stderr)
	get, _, err := root.Find([]string{"get"})
	if err != nil {
		panic(err)
	}
	cmd := &cobra.Command{
		Use:          "pin",
		Short:        "Pin resources for use in subsequent commands",
		Long:         pin_long,
		Example:      pin_example,
		SilenceUsage: true,
		ValidArgs:    get.ValidArgs,
		Run: func(cmd *cobra.Command, args []string) {
			if cmdutil.GetFlagBool(cmd, "clear") {
				sh.context = []string{}
			} else {
				err := setContextCommand(sh, args)
				cmdutil.CheckErr(err)
			}
			sh.lineReader.SetPrompt(prompt(sh.context))
		},
	}
	cmd.Flags().BoolP("clear", "c", false, "Clears pinned resource")
	root.AddCommand(cmd)

	cmd = &cobra.Command{
		Use:   "exit",
		Short: "Exit kubesh",
		Run: func(cmd *cobra.Command, args []string) {
			fmt.Println("Bye!")
			os.Exit(0)
		},
	}
	root.AddCommand(cmd)
	return root
}

func prompt(context []string) string {
	path := ""
	if len(context) > 0 {
		path = fmt.Sprintf("[%v]", strings.Join(context, "/"))
	}

	return fmt.Sprintf(" kubesh%v> ", path)
}


text:
Il pianale Chrysler LX è un tipo di piattaforma automobilistica sviluppata da Chrysler ai tempi dell'alleanza con Mercedes-Benz per vetture di taglia grande (come grandi berline, ammiraglie e coupé). Debuttata nel 2005 la piattaforma LX è in grado di supportare anche motori dall'architettura V6 e V8 ed è disponibile sia con trazione posteriore che integrale. Ha sostituito la precedente piattaforma LH del gruppo Chrysler.

Il contesto

Nascita e caratteristiche

La piattaforma LX è stata sviluppata dalla Chrysler ai tempi dell'alleanza DaimlerChrysler con lo scopo di realizzare una nuova gamma di ammiraglie a marchio Chrysler e Dodge equipaggiate con la trazione posteriore (o integrale); le precedenti grandi vetture del gruppo statunitense (quali la Chrysler 300M e la sorella Dodge Intrepid) erano basate tutte sull'ormai anziana piattaforma LH a trazione anteriore introdotta per la prima volta nel 1993, inoltre a causa di vincoli strutturali non potevano essere equipaggiate con i più grandi motori dall'architettura V8, molto graditi dal pubblico statunitense. Così alla Chrysler progettano la nuova piattaforma LX che doveva garantire maggior flessibilità d'impiego rispetto alla progenitrice LH e maggior comfort con migliori doti stradali a tutte le vetture che la utilizzassero come base. Inoltre utilizzando componenti tedeschi di origine Mercedes-Benz, come sospensioni e sterzo, sono stati ridotti i costi di produzione e i tempi di sviluppo.

In particolare la struttura adotta lo stesso schema di sospensioni anteriori della Mercedes-Benz Classe S (serie W220) con disegno a quadrilatero deformabile particolarmente raffinato che garantisce un comfort notevole rispetto al più comune MacPherson; al retrotreno è presente lo schema Multilink a cinque bracci (di cui tre in alluminio e due in acciaio) lo stesso adottato dalla Mercedes-Benz Classe E (serie W211).

Erroneamente, per i primi anni di produzione, la stampa indicava il pianale LX strettamente imparentato con il telaio della Mercedes Classe E serie W210, in realtà lo stesso Burke Brown che era a capo del progetto LX ha chiarito in una intervista che la piattaforma è interamente progettata da Chrysler e non utilizza i componenti della datata W210 bensì li eredita dalla più recente Classe E W211 (debuttata nel 2003 e prodotta fino al 2009) oltre che dalla più grande Classe S W220.

La maggior flessibilità d'impiego di questa piattaforma, rispetto alla vecchia LH, ha permesso di adottare oltre alla trazione posteriore anche quella integrale, i cui modelli erano identificati dalla sigla AWD. Il passo è di 3,048 metri.

La piattaforma LX debutta nel 2005 con le berline Chrysler 300C e la sorella più sportiva Dodge Charger; a seguire sarà utilizzato anche dalle rispettive versioni station wagon vale a dire la 300C Touring e la Dodge Magnum che utilizzavano sospensioni autolivellanti Nivomat che mantenevano costante l'altezza della vettura da terra. Oltre ai modelli di grande produzione, il telaio LX è stato utilizzato anche da alcuni concept car come la Chrysler Nassau.

I motori erano disposti in posizione longitudinale in blocco con il cambio, e potevano avere architettura V6 e V8.

Versioni a passo corto e passo lungo
Nel 2008 Chrysler introduce la variante a passo accorciato (ridotto a 2,949 metri) denominata piattaforma LC: questa versione è stata studiata appositamente per la coupé Dodge Challenger, più compatta nelle dimensioni rispetto alle ammiraglie Charger e 300C.
La variante LC è stata utilizzata anche nel 2009 dalla Chrysler 200C EV, il prototipo con motore elettrico che anticipava l'erede della Sebring, ma che non ha avuto un seguito produttivo a causa degli eccessivi costi di produzione.

Nel 2006 con il prototipo Chrysler Imperial il passo del pianale viene allungato fino a 3,124 metri (versione ribattezzata piattaforma LY); anche in questo caso si tratta solo di un aumento del passo senza modifiche all'avantreno o al retrotreno. La versione LY però non avrà un esito produttivo ma rimarrà allo stadio di prototipo insieme alla Imperial sotto la quale ha esordito.

Evoluzione
 Nel 2011 viene presentata una profonda evoluzione della piattaforma LX voluta dai vertici Fiat-Chrysler per la seconda generazione delle ammiraglie Chrysler 300C e Dodge Charger: in particolare vengono aggiornate le sospensioni, all'anteriore si trovano ora nuove sospensioni con schema Multilink, viene irrigidita la taratura rispetto a prima per migliorare l'handling delle vetture (soprattutto per i modelli destinati al mercato europeo come la Lancia Thema, la gemella della 300C) inoltre a aumenta la percentuale di acciai alto-resistenziali utilizzati per la costruzione della struttura e l'utilizzo di nuove leghe leggere contribuisce a diminuirne il peso della piattaforma di una decina di chilogrammi. Tutte le modifiche saranno apportate anche alla versione LC a passo corto.

Sul fronte della sicurezza sia la Chrysler 300C che la Lancia Thema sono state sottoposte ai crash test NHTSA ed Euro NCAP rispettivamente, ottenendo il punteggio massimo di 5 stelle in entrambe le prove.

La produzione
La piattaforma LX attualmente viene prodotta solo in Canada presso lo stabilimento di Brampton dell'Ontario di proprietà della Chrysler Group; in passato questo telaio è stato prodotto anche in Cina nello stabilimento di Pechino per mezzo di una joint-venture dell'era DaimlerChrysler per le vetture destinate al mercato locale. Dal 2006 al 2010 la piattaforma è stata assemblata anche a Graz in Austria presso lo stabilimento della Magna Steyr per mezzo di una joint venture specifica. In Austria venivano prodotti anche tutti i modelli di autovetture basate sull'LX con guida a destra; sempre a Graz veniva prodotto anche il sistema di trazione integrale 4Matic utilizzando le stesse linee di produzione della Classe E W211 che veniva prodotta nello stesso stabilimento.

Utilizzo
Chrysler 300C (dal 2005)
Chrysler 300C Touring (dal 2005)
Dodge Magnum (2005-2008)
Chrysler Imperial concept car (2006)
Dodge Charger (dal 2006)
Chrysler Nassau concept car (2007)
Dodge Challenger (dal 2008)
Chrysler 300 (dal 2011)
Lancia Thema (dal 2011)

Piattaforme derivate

Note

Altri progetti

Collegamenti esterni

Pianali Chrysler Group
Pianali Fiat Group Automobiles


The SPACE directive reserves a zeroed block of memory. % is a synonym for SPACE.
This limit is raised to 256MB in ADS 1.2, and to 4GB in RVCT 2.x and later, which is due to the maximum value of an integer. In RVCT 2.x and later, the equivalent error message is: "Error: #95: array is too large".


fees, get started with Bitcoin. Gotottack, hero Member, offline, activity: 882, merit: 506. Doesn't forget that you can convert to BTC and find rate of 50 units of local currency in Bitcoins. Also available next languages:. (Read 2439 times). 50 Bitcoins equal 733684.13 UAE Dirhams, how much is 50 Bitcoins. Org Most popular requests in March 2019 MoneyExchangeRate. Legendary, offline, activity: 1232, merit: 1026 flower1024, legendary, offline, activity: 1428, merit: 1000 piloder, legendary, offline, activity: 966, merit: 1006 oxygen88. 50 Bitcoins equal 1341939.71 Yuan, how much is 50 Bitcoins. Table below show fifty Bitcoins comparison with other currencies.
50 bitcoin in 10 jahren Bitcoins equal 50 Bitcoins Convert to: 50 Bitcoins Inverse Bitcoins 733684.13 UAE Dirham 0 Bitcoins.2 Afghani 0 Bitcoins.16 Lek 0 Bitcoins.61 Dram 0 Bitcoins 366481.32 Guilder.01 Bitcoins.7 Kwanza 0 Bitcoins 8340756.24 Argentine Peso 0 Bitcoins 282055.63 AU dollar.01 Bitcoins 359749.34 Aruban Florin. 50 Bitcoins equal.35 Indonesia Rupiahs How much is 50 Bitcoins in Singapore? Bitcoin is open-source; its design is public, nobody owns or controls Bitcoin and everyone can take part. 50 Bitcoins equal 13816699.61 Indian Rupees How much is 50 Bitcoins in Indonesia? Web tool for best quick conversion of currency. Compare Bitcoins exchange rate with other currencies in table. Find the latest world Currency Exchange Rates.
50 Bitcoins equal 1711146.41 Norwegian Krones, how much is 50 Bitcoins. This page let to convert Bitcoins to every local currency.
In fact, it is even possible to send a payment without revealing your identity, almost just like with physical money. It's organized through a network known as..
Ich nutze es seit Jahren und bin damit sehr zufrieden. Google AdSense, ist einfach einzubauen und optimiert sich zum Teil von selbst. Und erhalten dafür eine..


How can someone who hasn't created essays prior to compose just one? – When Will We Cry?
The research methods vary centered on the basis of research and the data. Generally speaking, the target of a PhD proposal will be to carry out your PhD dissertation readily. Research Paper comprises the ideal number of references needed by the mission.
uncover material which is regarding the firms which are that the foci of the paper. Interview documents enable one to use people as your sources to novels as an alternate. You need to present a review of the research work with objectives and its own goals.
More than 1 point might potentially be too challenging for the reader to recognize and also the writer to encourage. Make sure you write to appreciate what it is that you're writing or talking about. You might wish to consider the reader.
You can't compose a thesis statement for those who have zero understanding of what you're composing. It's believed to be the remaining portion of the paper's pre face. If it's added in the onset of the thesis newspaper positionA thesis statement is viewed as good.
It's therefore apparent that handling papers are written to disclose that the procedure for the management. You can also incorporate information from your compulsory readings on engine and brain growth. Your product will be published Since you will need to do the job to awake to that the market.
Now you own a couple of interesting choices when it regards an argumentative thesis statement. Come back for your thesis announcement as you're in possession of a rather first draft of your piece. Due to plagiarism, rejection of thesis' chances are so really significant.
It truly is therefore obvious that direction papers are published to reveal the procedure for the management. To prevent insufficiency of information, make sure each one of these information you intend to make use of is available from your origins. If it's an literary research that you're running, then you should make certain you decide on a literary portion of job that you are conversant which you enjoy.
The end result can be. From the event of an Argumentative thesis statement, but the announcement offers an arguable position within an problem. Most significantly, this makes a statement.
Every consideration should be concise and relevant. Some reasons lead youth. Because it doesn't maintain a posture Illustration Federal immigration law is just a trying dilemma about which a great deal of people disagree isn't a qualitative thesis.
Bear in your mind it's the previous part of your article that making it brief is indicated. Placing Your Purpose in place currently With your readeras consideration, you ought to make sure you additionally directly deal with the question or prompt to which you've already been requested to respond. It's still a fact you have to reevaluate that problem before moving on.
Nowadays you conscious of this simple actuality that argumentative thesis issues needs to have several features to become disagreed so you sometimes spend the conversation further. Every article or essay that you write needs to start somewhere which is why introductions and conclusions are crucial in making a highquality work . The best way is always to start with scanning it by way of a very first time.
Student doesn't use sources including Wikipedia. Consequently she or he has the ability to write direction documents Students needs to have the abilities and expertise in the area of direction. The college pupils will probably be provided the undertaking's fundamentals and also what the intention of the job would be to that a rubric.
Be skeptical once you discover your creating to explaining details crossing-over. It's important to get an in depth understanding of the ideas which you will mention in your own essay. The hardest aspect of composing could be the very first sentence.
It's possible to see the example button in every department. With no of publication span when it's too broad it cannot be supported. As soon as you do then craft and you will need to decide to take to that to some declaration.
You have to locate an interest. If you've practiced the structure you should have superb idea about exactly everything you might reach within half one hour to each essay. If at all your composition will be any good you have must go in your pace.


Stella McCartney's Macy sneakers come in a chic monochrome colourway and are detailed with panels of clashing textures. Woven sections bring a tactile edge, while the espadrille-style jute layer adds a rustic touch. Give your summer dresses a dash of contemporary-cool style with this statement starry pair.


text:
Home > Case Law > Criminal Law > Pate v. Robinson
Pate v. Robinson Cartoons
Pate v. Robinson
Under state law, a defendant must be afforded a hearing to determine his competency to stand trial when evidence suggests the defendant may have suffered from insanity at the time the crime was committed. Incompetency.
McCleskey v. Kemp
In the Interest of M.T.S.
Sexual assault consists of any act of sexual penetration done without the affirmative and freely given permission of the victim. Juvenile delinquency.
People v. Hall
Ski accident, Whether a risk of death is substantial and unjustifiable must be determined based on the circumstances of each case.
People v. Burton
The underlying felony sufficient to trigger the felony-murder rule must involve an independent felonious purpose, lesser included offense.
Inmates of Attica Correctional Facility v. Rockefeller
Selective prosecution, courts are reluctant to interfere with prosecutorial discretion.
Brady v. United States
A guilty plea is not involuntary merely because it was entered into to avoid the possibility of the death penalty.
Felony Murder Rule
People v. Cavitt; The felony-murder rule requires both a causal relationship and a temporal relationship between the underlying felony and the act resulting in death.
Perjury By Implication Not Allowed
Bronston v. United States; To support a perjury conviction, a witness must actually willfully state a material matter that he does not believe to be true.
Discipline or Child Abuse
Willis v. State; parent has fundamental right to direct his or her child's upbringing, which includes the right to use reasonable or moderate physical force to control the child's behavior.
Taylor Overruled
People v. Superior Court; doctrine of "nonmutual collateral estoppe" should not be applied in criminal cases.
Question of Possession
State v. Barger; new technology complicates questions of possession sufficient to establish criminal liability.
Honest Services Fraud Doctrine
Skilling v. United States; bribery and kickbacks are honest services fraud, but conflict of interest is not.


If you've been following our recent news announcements you know how excited we are to be launching our innovative new product OnMedia, together with Brainstorm at NAB next month.
OnMedia is the productised result of 2 years of research, development and integration in the context of the EU Horizon 2020 VisualMedia project that we ran in close corporation with 11 other leading industry and academic partners from around the EU. We're proud to debut this innovative technology that enables broadcasters to manage and publish content into 3D interactive graphical environments via a single, simple interface.
OnMedia is a uniquely packaged end-to-end solution for social management and broadcast graphics. The integrated, yet modular application combines Brainstorm's industry-leading 2D/3D graphics engine with never.no's unique technology for social media management. OnMedia makes it easy to search, filter, select and fine-tune user-generated content and to preview, publish and control it in real-time, forming cutting edge interactive 3D graphics.
In the last 25 years, the competitive and commercial pressure in the television industry has increased tremendously as a result of an ever-increasing number of channels and digital platforms viewers can choose from to access their favourite content. To retain viewers, Social TV –being the union between television and social media– has become a recognised and proven proposition that adds social and interactive elements to traditional broadcast formats, with the aim of making those formats more personal, dynamic and attractive for viewers, which in the end decreases churn.
The main obstacle for Social TV is that social and broadcast are completely disjunct markets and that so far, all marriages between the two have led to non-standardised, non-reusable, non-scalable, ad-hoc point-solutions. OnMedia resolves this by offering a proven, scalable, flexible, standardised and repeatable proposition that bridges both worlds. Out of the box, it immediately helps broadcasters enhance the value their viewers experience, which in turn, directly drives higher audience ratings and fosters loyalty among their viewers. We mean this quite literally: the necessary time to set up and integrate OnMedia from scratch to commercially active is measured in hours.
OnMedia provides the capability to manage complex and diverse data from a wide range of social media channels, and to publish this into engaging interactive graphical elements for a jaw-dropping consumer experience. Functionally it offers the full spectrum of integrated technologies, ranging from a Social Media Engine and an Online Distribute Engine for 2nd screen apps, to a Graphics Engine, a Tracking Engine and a Gestures Engine for real-time control of interactive 2D/3D graphics in combination with VR or in-studio AR with moving cameras. This highly innovative product is the world's first fully-integrated solution for managing the entire end-to-end production chain of Social TV.
But there is more. OnMedia goes beyond the basic requirement of publishing live social data in visually dynamic TV formats, by addressing a fundamental, yet often ignored, shortcoming of production flows in traditional broadcast environments. Whilst visualisation is key, the ability for producers, journalists and editorial teams to adapt visual formats in real time when simple creative changes are necessary, without going back to the drawing board and redesigning the graphics again, is something that is missing in the industry. OnMedia offers this possibility as part of its core offering and needless to say, this saves a enormous amount of production effort and lead time. With the OnMedia solution all graphics, 2D or 3D, interactive or steered, VR or AR, can be parametrized for further fine-tuning, customisation and real-time control at any point later in the production chain.
In addition the scalability and repeatability of the OnMedia solution implies that it is able to serve the needs of local and regional TV stations, national broadcasters and production houses, while offering the same attractive feature set at any scaling point. The solution is a pre-integrated, economic, powerful and reliable component in the broadcast production workflow and minimises the need for expensive man or machine resources, while remaining agile enough to be able to cope with today's flexibility requirements.
Visit us at stand SL4616 to get a first-hand look at the state of the art integrated 3D graphics system with social publishing capabilities.
Being never.no's sole Dutch employee, Taco frequently smuggles cheese and stroopwafels from his home country into Oslo and constantly tries to understand Norwegian culture. In his spare time he's obsessed with cats and penguins, theoretical physics and leads a parallel existence as garagerocker and concert-dj. Not always simultaneously though.


•	CM KPK will be announced on August 11, says Riffat ullah Aurakzai.
•	ECP wants to investigate the RTS failure, says Adeel Waraich.
•	Firms doing business with Iran will be barred from the United States, President Donald Trump said on Tuesday, as new US sanctions took effect in spite of pleas from Washington's allies.
Iran dismissed a last-minute offer from the Trump administration for talks, saying it could not negotiate while Washington had reneged on a 2015 deal to lift sanctions in return for curbs on Iran's nuclear programme.
•	Trump decided this year to pull out of the agreement, ignoring pleas from the other world powers that had co-sponsored the deal, including Washington's main European allies Britain, France and Germany, as well as Russia and China.


This kit has over 168 beads and 2m of elastic for threading. The kit is presented in a clear re-usable bead tube. The has a combination of plastic pony (barrel shaped) beads, star beads, skulls beads and three different plastic themed beads (a bats, witch and a glow in the dark pumpkin).
This kit will would make an ideal gift or fun half term activity, perfect for those Halloween parties.


Water temperatures are holding in the low 50's but expect them to continue to drop this week with temperatures in the high 30's and even snow in the forecast.
Both Minnesota and Canadian walleye fishing are on fire with only a jig and shiner or minnow needed. Look for Walleye in areas of current, pinch points between islands or rocky bays. Fish are currently shiner dependent in 17-25 feet.
Crappies are being found away from the rocks suspended over mud bottoms in 24-28 feet.
Perch can be found on deeper reefs topping out at 28 feet.
Muskie trolling is off to a great start and will only continue to get better as the water temperature reaches into the high 40's.
We will be closing down for ice in October 22nd - we hope to see you before then for some late fall fantastic fishing!


Total square footage: 1,920 sq.ft.
Extra deck, patio or wraparound deck is additional cost.
*Refrigerator/freezer and over the range hood fan sizes vary based on layout.
*Dedicated master ensuites are plan specific.
**Porcelain tile floors in all bathrooms with radiant infloor heating in dedicated master ensuites are plan specific.
Is your heart ready to find its home?
Yes? Great! We'd love to help you.
The developer reserves the right to change floor plans, elevations, specifications and pricing without notice or obligation. All floor plans are for illustrative purposes. All floor plans, maps, landscaping and elevation renderings are artist's conceptions. Drawings are not to scale. All square footages could change and are approximate. All floor plans, decks and patios will be modified as necessary to fit site conditions, views, topography and safety issues at the discretion of the developer. Decks are for illustrative purpose only. All decks and patios are 150 sq.ft. and are site dependent.


my query is how do i get to have the L & R waveforms during audio track recording in my Ableton Live - LE/6?
even if i have set the audio preference with both 1&2 I/O to be mono & stereo, i still get only 1 side of the waveform during recording.
shifting the guitar signal to either L or R hi-Z line of the 0404, the recorded waveform only shows in L or R with respect to the 0404 line input.
also, is it necessary, to be able to have the functioning L & R, to have the Center Panning to be effective? coz i think it is so.


the immigrant community of Charlotte.
To participate in the AmeriCorps ACCESS Project, applicants must: Be at least 17 years old, have a High School Diploma or GED, Have English proficiency (spoken/written), Have computer Skills, and meet any additional requirements as determined by the site agency (see below).
and/or the incumbent is hired for expertise or ability to perform the function due to its high specialization.
The Americans With Disabilities Act of 1990 (ADA) and associated Federal regulations protect qualified individuals with disabilities from discrimination in all areas of employment. To be considered qualified; an individual must be able to perform the essential functions of a position, with or without reasonable accommodation. It is important that the physical tasks associated with the essential functions be identified appropriately so that persons with disabilities can determine if any accommodation is necessary.
Collaborate with Volunteer Coordinator and Education Manager to recruit volunteer mentors to mentor and tutor at-risk immigrant and refugee high school students.
Collaborate with Volunteer Coordinator and Education Manager to train volunteer mentors on their role and responsibilities as mentor to a high-risk immigrant and refugee high school students.
Collaborate with Charlotte Mecklenburg School (CMS) staff to prepare immigrant and refugee students and their families for involvement in the mentorship programs.
Coordinate mentorship and tutoring details by working with CMS staff to ensure students and school space will be available.
Match community volunteer mentors to students to form the best mentorship match possible.
Provide support and education to parents of teachers so they will give permission for their students to participate and offer the support necessary for their children to excel in school.
Maintain all program documents and materials as necessary. Keep items up-to-date and readily available. This includes all presentations, presentation materials, flyers, information handouts to students, families and mentors, etc.
Document all interaction with every student in the database.
Inform Volunteer Coordinator of any program changes or if a volunteer mentor drops out.
Distribute promotional materials regarding mentorship in the community.
Organize celebrations for students and mentors at the end of the semester/before graduation.


text:
Modernism/Postmodernism
Peter Brooker
Published May 26, 2016 by Routledge
Published September 25, 2014 by Routledge
The concepts of 'Modernism' and 'Postmodernism' constitute the single most dominant issue of twentieth-century literature and culture and are the cause of much debate. In this influential volume, Peter Brooker presents some of the key viewpoints from a variety of major critics and sets these additionally alongside challenging arguments from Third World, Black and Feminist perspectives. His excellent Introduction and detailed headnotes for each section and essay provide an indispensable guide to interpreting the many different opinions, and prove to be valuable contributions in their own right.
General Editors' Preface Acknowledgements Editor's Preface Introduction: Reconstruction Part One: Modernist postitions 1. George Lukaacs, from ". Bertolt Brecht from 'The Popular and the Reaslistic.' 2. Walter Benjamin, from 'The Work of Art in the Age of Mechanical Reproduction.' 3. Theodor Adorno 'Letter to Walter Benjamin.' 4. Peter Burger,'Avant-Gaarde and Engagement.' Repositioning Modernism 5. Marshall Berman, 'The 20th Century: the Halo and the Highway.' 6. Raymond Williams, 'The Metropolis and the Emergence of Modernism.' 7. Jean Radford, from 'Coming to Terms: Dorothy Richardson, Modernism and Women.' 8. Houston A Baker, from "Modernism and the Harlem Renaissance." 9. Laleen Jayamanne, Geeta Kapur and Yvonne Rainer, from 'Discussing Modernity', Third World and "The Man who Envied Women." Part Two: Postmodern Narratives 10. Jurgen Habermas, 'Modernity - and Incomplete Project.' 11. Jean-Francois Lyotard, 'Answering the Question: What is Postmodernism?' 12. Jean Baudrillard, from 'Simulacra and Simulations.' 13. Frederic Jameson, 'Postmodernism and Consumer Society.' Popular Capitalism and Popular Culture 14. David Harvey, from 'The Constitution of Postmodernity'. An Enquiry into the Origins of Social Change. 15. Ian Chambers, Contanimation, Coincidence and Collusion, Pop Music, Urban and the Avant-Garde. A Feminist Postmodernism? 16. Julia Kristeva, 'Postmodernism?' 17. Laura Kipnis, from Feminism: the Politcal Conscience of Postmodernism?' Black Culture and Postmodernism 18. Cornel West from 'An Interview with Cornell West Anders Stephanson.' Post Modernist Fiction 19. Umberto Eco, 'Postmodernism, Irony, the Enjoyable.' 20. Linda Hutcheon, 'Telling Stories: Fiction and History.' 21. Carlos Fuentes, 'Words Apart.' Notes on Authors Further Reading Index
Longman Critical Readers
Postmodernism Literature
Literature by Period


Bourns MF-NSML Series PPTC Resettable Fuses offer a maximum operating current of 1.5A to 6.0A, post-trip resistance values as low as 12mΩ, and initial resistance values as low as 1mΩ. These low resistance values help boost the current carrying capability of the MF-NSML series. The MF-NSML fuses allow Bourns to offer a 6A Ihold model in a 1206 package.
These compact NSML models use Bourns' freeXpansion™ design that increases the performance of the resettable fuse with higher hold currents, higher voltage, improved resistance stability, and smaller footprints. Typical applications include PC motherboard port protection, USB memory modules, gaming consoles, and battery protection for smartphones.
You can check out our ptc resettable fuse products here.


text:
Mursko Središće (ungerska: Muraszerdahely) är en stad i nordvästra Kroatien, vid gränsen till Slovenien och Ungern. Staden är centralort i Međimurjes län som ligger i centrala Kroatien. I staden finns cirka 5 985 personer (31/12 2019) och dess yta är 33.90 km²

Mursko Središće, den nordligaste staden i Kroatien, kallas också "Gruvarbetarnas stad", som betonar gruvdriftens betydelse för staden under gången tid. Från staden går vandringsleden Mura Miners Track, en 12,5 km lång stig. Längs leden finns det 10 informationstavlor som var och en täcker ett ämne, som stadens historia, gruvhistoria, floden Muras betydelse.

Referenser

Källor

Orter i Međimurjes län
Gränsorter i Europa


text:
Intel eyes the future of wearables with Recon acquisition
Intel has confirmed the completed acquisition of Recon Instruments, maker of the Recon Jet smart eyewear for sports and high-intensity environments. Recon was formerly an Intel Capital portfolio company. The acquisition gives Intel 'a talented, experienced wearable computing team that will help expand the market for head mounted display products and technologies.'
Intel notes that existing customers and retailers of Recon products can 'rest assured they'll continue selling, enhancing and marketing their products under the Recon brand without disruption.' The Recon team will also partner with Intel's New Devices Group to develop smart device platforms for a broader set of customers and market segments.
It's been a busy few months for Recon. After an original unveiling in June 2014, the company's Recon Jet smart glasses started shipping in April 2015. Then, in early June, Recon introduced Refuel, 'a groundbreaking smart nutrition app for Recon Jet smart eyewear.' And, last week, Recon announced a partnership with professional triathlete and IRONMAN champion Andrew Starykowicz.
Intel is seen as an ideal partner for Recon. Intel's CEO, Brian Krzanich, made his commitment to wearable technology very clear shortly after assuming his current role in 2013. He reaffirmed that commitment in his keynote speech at the Consumer Electronics Show this January. Brian Krzanich and his team, including New Technology Group head Josh Walden, are understood to share Recon's vision for the 'potential of smart eyewear in the consumer and enterprise markets, and this deal reflects that shared vision.'
Dan Eisenhardt, CEO of Recon Instruments added, "As part of Intel, we'll have the resources to continue the mission we began with the creation of Recon in 2008, but with a level of efficacy and speed that's beyond the reach of a pioneer in a new market. We'll stay right here in Vancouver, and we'll retain our talent, our brand, and our entrepreneurial spirit."
He continued, "Thanks to Intel, however, we'll gain two very important strengths:
"We'll have the resources to successfully grow. This growth will extend to our developer relations program, which will help us establish and sustain a strong app ecosystem.
"In addition, we'll have the opportunity to draw from Intel's extensive technology portfolio. As the world's most successful semiconductor company, Intel has valuable technical resources and expertise to bring to the table."
Josh Walden, Senior Vice President and General Manager of Intel's New Technology Group said, "We are excited to welcome the Recon team to Intel, and we look forward to the amazing experiences we'll invent together."
Intel adds that the growth of wearable technology is creating a new playing field for innovation, and the company has 'made tremendous strides in developing products and technologies to capture this next wave of computing.'
For example, in the last six months, Intel unveiled a multiyear R&D collaboration with Luxottica Group and its Oakley brand to 'fuse premium, luxury and sports eyewear with smart technology'. It also announced a partnership with TAG Heuer and Google to launch a Swiss smartwatch powered by Intel technology and Android Wear.
www.reconinstruments.com
www.intel.com
Previous articleFeetures!' plantar fasciitis products distributed direct from manufacturer
Next articleChallenge San Gil sets the stage for expansion in Mexico
AfterShokz reports 'record global sales growth in 2019'


The CH322 by Hans J. Wegner is an extendable dining table in solid wood with a stainless steel base.
Material: Solid Oak table top available in a soaped, clear lacquered, oiled or white oiled finish.
Accommodates one or two extension leaves in either grey or black MDF, or oak extension leaves in the same finish (W 95cm L 60cm).


text:
Dead Air Radio
You only tune in when the end is near
Written by T. Bird November 17, 2018 September 6, 2019
"Come on Grandma. Smile."
Wincing in the light, Gertrud thought for a moment, trying to find the proper English words for her grandson.
"It's bright out here," she said through her soft accent.
"I know Grandma. But you look very pretty today."
Gertrud smiled as best she could in the bright light of the afternoon sun.
Tim pressed the shutter button and the little black and silver box made a small "clack" sound. Tim rested the camera against his leg, looked up at his grandmother and smiled.
Gertrud wished she had a camera herself.
Behind Tim was her quiet street with sidewalks and tall trees. Perfectly manicured lawns before every big wonderful house. Neighbors waved and smiled and came to visit on Sundays after church. Even during the war no one had mistreated her for her German heritage. More than anything, they were concerned for her worry about her remaining family in Germany.
And there was Tim himself, a growing, kind, wonderful boy. The night he was born Gertrud held him in her arms and wept, only ever letting him go because she knew the boy would need his mother and father as well.
As far as she was concerned, her life could not have gone better if she'd planned it. Harold was gone. That was true. She missed her husband every single day.
"I know you're going to miss me when I'm gone," Harold once told her. "But you take your time following me. I'm not going anywhere. You're my Heaven."
A sad smile crept over Gertrud's lips. Her eyes glittered, welling up with tears. How she missed that man.
"Grandma? Are you ok?" Tim fidgeted with his camera, looking at her.
She flapped her hand at him.
"I'm just fine. It's the sun. There's too much sun!" Gertrud turned around and began to shuffle back toward the house. "Come. Come sit with your grandmother."
The two seated themselves on the porch in the white rocking chairs Harold had bought so many years ago. They sat for a moment, enjoying the silence of a quiet Saturday afternoon.
"Grandma?"
She turned to him with concern already written on her face. The tone of his voice, not requesting a snack, but wonder with a hint of worry in there.
"Did my dad kill people? When he was in the war? Mom said not to ask him about it and she won't tell me either."
Gertrud put her hand on her grandson's forearm.
"Why is this important to you?"
"I guess because…" Tim licked his lips and thought for a moment. "I guess because I worry about something bad happening at home. Like robbers or something. And I think if dad had killed anyone in the war then he'll be a lot better at protecting me and mom."
"Timothy," Gertrud began. "Your father loves you more than I do. And I love you more than anything else in this life. Your father would do anything to protect you."
Gertrud smiled, love radiating from her like a heat.
Tim continued to look discouraged. Gertrud then looked to the street and back to her grandson.
"I don't know if your father killed anyone in the war. That is the truth. But I must tell you a secret. Even your father doesn't know this and he has lived with it his entire life."
Tim looked up, confused and excited.
"Come," she said, making an effort of getting out of her rocking chair. "Come inside and I will show you."
Tim held the screen door open as Gertrud shuffled into the house, her thick soled shoes clicking loudly on the hardwood floor. They passed through the living room, clean, sparse, though still homey with family pictures hung on each wall. They passed through the kitchen where Gertrud fixed the finest family dinners. Gertrud led Tim down into the basement.
Gertrud liked the basement. Either it still smelled like Harold or Harold always smelled like the basement. Here was his workshop where he would fix and build things from around the house. Here he would get far too excited about baseball games on the radio as Gertrud smiled and washed the dishes.
It was also here where Harold kept the safe, his logic dictating that no one would dig around in that mess in the basement to try and find their valuables.
Gertrud walked to the workshop table and slid a stack of books to the right to reveal a small but very secure looking safe, about two and a half feet in height. She turned back to Tim, who was fidgeting in his anticipation. She returned her attention to the safe.
"Five," she said as she turned the knob with a faint click. "Thirty-five," Gertrud reversed the direction of the knob. "Five."
"I used to say that your grandfather was the kindest man in the world," Gertrud shuffled papers around inside the safe. "And he used to say to me 'Gerty, you can say that when you've met every other man in the world.'" She stopped a moment to control her emotions.
On the table, with her back to Tim, she placed a handgun.
Tim had never seen a gun before. The sound it made when placed on the table made it sound much heavier than anything he'd seen in the movies. His heart pounded.
Gertrud turned around, her hands placed behind her back.
"Very long ago, when I first met your grandfather, I knew that people were frightful, unkind, and they worried so much even about the color of one's skin. But he did not care. He was a young man, camping in the Black Forest when I came upon him. I was injured and alone. I couldn't speak the same language as him. But he helped me."
Gertrud put her hand to her chest, moved her eyes to the ceiling, and wiped away the tears.
"We fell in love. And this is the only thing I have left of the life I led before I met him. I was his completely. So I gave it to him."
She turned, Tim expected her to reach for the gun, but she reached behind her. She handed him a small rag with something hard inside. Tim opened the rag to find a small dagger made from bone. He looked up to his grandmother.
"It was the only weapon I had when your grandfather found me during the Secret Skeleton Wars." Gertrud beamed. "Timothy, you are one quarter Skeleton."
"What?" Tim seemed genuinely lost.
"Oh, I was such a young skeleton then. My bones were still pearly white and I was fantastically excited to rip the flesh from the upstart human race and create more of our own!" Gertrud found Harold's old workbench and sat. "'Off with their face for a better race' was my platoon's motto."
Tim continued to hold the dagger in his upturned hands like an offering, uncertain of what he was hearing.
"One fateful night the Skeleton Army had planned a night raid on a village in Germany. We were to dig our way up from the cemetery at midnight but the Cydonian Knights of Lazerhammer were waiting for us. All of my comrades were crushed to dust. I only managed to make it out because I'd gotten trapped in a particularly hard to open coffin and when they came looking for me I played dead."
Gertrud held her arms up in the air, parallel to one another, palms facing inward, as if to either say "I will never forget my side in the Secret Skeleton Wars" or "it's good."
Gertrud lowered her arms and continued her story.
"I spent days wandering the forest, avoiding Sky Pirates, dodging Meat Patrols, and in the end I was finally taken down by a stray dog." The old woman smirked at the idea. "I was thankful he only ran off with a rib but I was still very much gnawed upon. It wasn't more than an hour later I came upon a young man sitting by a campfire. Oh, he was lovely."
Tim was looking sad and worried.
"I saw the smooth skin of his face and those muscular arms and… I was not disgusted. Nor did I want to tear them from his wonderful bones. In fact, I remembered when I was alive and I had skin and hair and lips. I longed for them again so that maybe this man would touch me and care for me and love me."
Gertrud paused for a minute.
"You see Timothy, the reason Skeletons are so dangerous is because they don't feel touch, therefore cannot feel pain. Are you harder to hurt than the other boys at school?"
Uncertain of how to answer, Tim remained still, his mouth hanging open in shock.
"When your father returned home from the war he told me of how he had been shot many times and never felt it, never ceased charging the enemy. I don't know if he killed another man in the war. But I can tell you that he has the heart of a father, the skill of a soldier, and the courage of a Skeleton."
I hate you, John
áarudaahga: a warning
The children can hear it
Happy New Fear
Previous Post Jesus Camp
Next Post Happy New Fear


What does it mean to be college ready?
College readiness means a high school student has the knowledge and skills necessary in English and Mathematics to qualify for and succeed in entry-level, credit-bearing post-secondary courses without the need for remediation.
The Texas Success Initiative (TSI) is an assessment designed to determine if a student is ready for college-level course work in the general areas of reading, writing and mathematics. The test will determine what type of course or intervention will best meet the student's needs and to assist in becoming better prepared for college-level course work.
DO I HAVE TO TAKE THE TSI TEST?
Students who do not meet one of the following exemptions must take TSI Assessment prior to enrolling.
3. STAAR end-of-course (EOC): minimum score of Level 2 on English III exempts reading and writing (minimum scale score 2000), minimum score of Level 2 on Algebra II exempts math (minimum scale score 4000).
4. See institution for other exemptions.
*ACT/SAT scores not older than 5 years and from same test date. TAKS scores not older than 5 years. Partial exemptions are allowed.
HOW DO I SIGN UP FOR THE TSI TEST?
Due to Garza's self-paced program, students are seen individually by Ms. Espinoza to set a testing date.
WHERE DO I TAKE THE TSI TEST?
Testing will occur in the College/Career Center starting promptly at 9:30. The test is untimed. For more details, check in with Ms. Espinoza.
Do I have to take all 3 parts of the exam? What are the passing standards?
Students must test only in areas not exempted or deemed not college ready. Every student is required to complete a Pre-Assessment Activity (PAA) before taking the TSI Assessment.
*The test is un-timed. Students cannot bring calculators - they'll only be allowed to use the calculator app provided by the test. Students may retest at any time. However, between testing sessions, students MUST PROVIDE PROOF OF PREPARATION for the re-test. This can be in the form of online test prep or in-person tutoring.
What happens if I do not pass all sections?
You must enroll in a developmental course every semester (Fall/Spring/Summer I/Summer II) until you clear all three sections of TSI. Dropping a developmental course may result in a TSI violation. Talk to a college adviser before dropping any developmental course.


PlayStation LifeStyle is your best source for all things PlayStation, including PS4, PS5, PS3, PSN, PSVR, and Vita News, Reviews, Trophies, Guides, and more!
Domain Name Systes (DNS) translates easily memorized domain names to the numerical IP addresses needed for the purpose of locating computer services and devices worldwide. There are total 12 DNS record(s) of playstationlifestyle.net.


Over 20,000 tanks across the USA use this technology! These monitors can be installed in existing tanks or with new construction. Each tank comes with detailed instructions for installation and monitoring. The wireless model (GW-300) requires a $250/year subscription for cellular expense and online access to data.


Reader... - DON'T BE AFRAID OF THE DARK; IT'S A PLACE WHERE YOU CAN HIDE.
Hello from Colorado. I wanted to take a minute and say thank you to anyone who has read my Wake Me book. You've put me at #71 on Amazon. Also, reviews have slowly started to come in on various sites so if you've taken the time to write one, thank you. -E.E.


text:
The National Capital Territory of Delhi has 11 administrative districts. Below is a list of the various District centres of Delhi:

South Delhi
 Nehru Place
 Saket District Centre

East Delhi
 Laxmi Nagar

Central Delhi
 Jhandewalan
 Rajendra Place

North West Delhi
 Manglam Place (Rohini)
 Netaji Subhash Place (Pitampura ; Shakurpur ; Wazirpur)

West Delhi
 Janakpuri
 Shivaji Place (Rajouri Garden)

See also
Districts of Delhi

References
Master Plan for Delhi 2021


text:
Nokia 1100 Coming Back Again
Nokia 1100 feature phone is most sold mobile phone in the world mobile market. New production of Nokia device stoped when the company was bought by microsoft corporation in April 2014. Nokia lover should be happy to know that Nokia 1100 is coming back again with exclusive feature and outlook.
Walton Primo ZX2
Walton Micro-Tech Corporation is going to release an attractive Smartphone Walton Primo ZX2. Some special feature and technology are included in ZX2 which will give user new experience and special opportunity.
Bangladesh Machine Readable Passport (MRP) Online Application
Government of The People's Republic Bangladesh, Department of Immigration and Passports has give all Bangladeshi a great opportunity to apply for a machine readable passport (MRP). It is a easy way to get a passport for all Bangladeshi with out any troube like before.
Bangladesh is enriched with its long history, arts and culture. The country is known as land of river and here common people formed a enriched heritage in different regions.
Chittagong, is a commercial capital of Bangladesh has a busy international sea port and airport. it has green hills, spacious sandy beach and elegant cool climate always attract the holiday- makers described by the Chinese traveler and poet, Huen Tsang.
Barishal is a division of Bangladesh which is situated southern part of the country and on the bank of Arialkha River. It is bounded by Dhaka in north, chittagong in the east, Khulna in the west and bay of Bengal in the south.
The Historical and Beautiful Capital City Dhaka
Dhaka is a busy city which is the capital of Bangladesh with its magnificent heritage, glorious culture and dazzling sceneries marks its four hundred years as capital city in 2008. Dhaka with the blend of traditional and modern architectural development possesses a plethora of splendours. It is founded in 1608 as the seat of Mughal Vicroys of Bengal.


text:
Is it a Mug or Cup? Recent Progress in Fuzziness Studies
Where does a cup end and a mug start? And vice versa? Help towards answering this consistently vexing question can be found in an essay by Brett Laybutt entitled A Corpus Study of 'Cup of [Tea]' and 'Mug of [Tea]' In which he cites the work of scholars who have tried, over the years, to crack its complexities – e.g. the work of Professor William Labov of the University of Pennsylvania.
"One of the first, and most influential, was Labov"s (2004) original 1975 experiment in which subjects were shown pictures of varying indeterminacy and asked to label them."
"From this, Labov was able to come up with a mathematical definition of 'cup'. "
Further reading : Labov, W. (2004). "The Boundaries of Words and their Meanings". In B. Aarts, D. Denison, E. Keizer, & G. Popova (Eds.), Fuzzy Grammar: A Reader. Currently available at £185 from Oxford University Press.
Coming soon : How much water is in a cup of tea?