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Home Research Recent Publications Personnel Salomon CV Publicity Funding
Complete List of Publications
Published Abstracts of Papers Presented
University of Chicago, Illinois, B.S., 1966, Chemistry
University of Wisconsin, Madison, Ph.D., 1971, Organic Chemistry (J. A. Berson)
Thesis: "Part I: Thermal Unimolecular Carbomethoxyl Migrations; Part II: Approaches
to the Study of the Stereochemistry of Vicinal Free Radical Elimination"
University of Wisconsin, Madison, Postdoctoral Research Associate, 1970-71, Bioorganic Chemistry (C. J. Sih)
Indiana University, Bloomington, Postdoctoral Research Associate, 1971-73, Homogeneous Catalysis (J. K. Kochi)
1970-71 Research Associate, Pharmacy Department, University of Wisconsin, Madison
1971-73 Research Associate, Department of Chemistry, Indiana University, Bloomington
1973-79 Assistant Professor of Chemistry, Department of Chemistry, Case Western Reserve University, Cleveland, Ohio
1979-84 Associate Professor of Chemistry, Department of Chemistry, Case Western Reserve University
1984-2009 Professor of Chemistry, Department of Chemistry, Case Western Reserve University
2010- Charles Fredrick Mabery Professor of Research in Chemistry
2018- Professor of Ophthalmology, Department of Ophthalmology & Visual Sciences, Case Western Reserve University
Awards and Professional Activities
1967-70 NIH Predoctoral Fellow, Department of Chemistry, University of Wisconsin, Madison
1995-98 Arthur C. Cope Award Canvassing Committee
1997-99 Morley Award Selection Committee
2003 Mortar Board "Top Prof" Award
2005-06 Chairman Cleveland Section of the American Chemical Society
2003- Numerous NIH Study Sections (Ad Hoc)
2006 Cleveland Clinic Innovator Award
2009- Editorial Advisory Boards: Chemical Research in Toxicology, Journal of Lipids, Organic Chemistry International
2012-16 NIH Synthetic and Biological Chemistry A Study Section
2015- Director, Visual Sciences Research Center Tissue Culture & Hybridoma Core
2019- Associate Editor, Free Radical Research
227. Bi, W., Jang, G. F., Zhang, L., Crabb, J. W., Laird, J., Linetsky, M., and Salomon, R. G. The Adductomics of Isolevuglandins: Oxidation of IsoLG Pyrrole Intermediates Generates Pyrrole-Pyrrole Crosslinks and Lactams. High Throughput, 2019, 8.
226. Cheng, Y. S., Linetsky, M., Gu, X., Ayyash, N., Gardella, A., and Salomon, R. G. Light-induced generation and toxicity of docosahexaenoate-derived oxidation products in retinal pigmented epithelial cells. Exp Eye Res, 2019, 181, 325-345.
225. Yakubenko, V. P., Cui, K., Ardell, C. L., Brown, K. E., West, X. Z., Gao, D., Stefl, S., Salomon, R. G., Podrez, E. A., and Byzova, T. V. Oxidative modifications of extracellular matrix promote the second wave of inflammation via beta2 integrins. Blood, 2018, 132, 78-88.
224. Linetsky, M., Bondelid, K. S., Losovskiy, S., Gabyak, V., Rullo, M. J., Stiadle, T. I., Munjapara, V., Saxena, P., Ma, D., Cheng, Y. S., Howes, A. M., Udeigwe, E., and Salomon, R. G. (2018) 4-Hydroxy-7-oxo-5-heptenoic Acid Lactone is a Potent Inducer of the Complement Pathway in Human Retinal Pigmented Epithelial Cells. Chem Res Toxicol 2018, 31, 666-679.
223. Liu, Y.; Zhang, Y.; Wu, C.; Zhu, J.; Wang, C.; Tomko, N.; Linetsky, M. D.; Salomon, R. G.; Wang, Y.; Yu, X. "High-resolution dynamic oxygen-17 MR imaging of mouse brain with golden-ratio-based radial sampling and k-space-weighted image reconstruction", Magn Reson Med 2018, 79, 256-263.
222. Cheng, Y. S.; Yu, W.; Xu, Y.; Salomon, R. G. "Total Synthesis Confirms the Molecular Structure Proposed for Oxidized Levuglandin D2", J Nat Prod 2017, 80, 488-498.
221. Salomon, R. G. "Carboxyethylpyrroles: from hypothesis to the discovery of biologically active natural products" , Chem Res Toxicol 2017, 30, 105-113.
220. Wu, C.; Wang, X.; Tomko, N.; Zhu, J.; Wang, W.R.; Zhu, J.; Wang, Y.; Salomon, R. G. "2-(ω-Carboxyethyl)pyrrole antibody as a new inhibitor of tumor angiogenesis and growth"Anti-Cancer Agents Med Chem 2017, 16, 813-820.
219. Guo, J.; Linetsky, M.; Yu, A. O.; Zhang, L.; Howell, S. J.; Folkwein, H. J.; Wang, H.; Salomon, R. G. "4-Hydroxy-7-oxo-5-heptenoic Acid Lactone Induces Angiogenesis through Several Different Molecular Pathways", Chem Res Toxicol 2016, 29, 2125-2135.
218. Bi, W.; Jang, G. F.; Zhang, L.; Crabb, J. W.; Laird, J.; Linetsky, M. D.; Salomon, R. G. "Molecular structures of isolevuglandin-protein cross links", Chem Res Toxicol 2016, 29, 1628-1640.
217. Guo, J.; Hong, L.; West, X. Z.; Wang, H.; Salomon, R. G. "Bioactive 4-oxoheptanedioic monoamide derivatives of proteins and ethanolaminephospholipids: products of docosahexaenoate oxidation", Chem Res Toxicol 2016, 29, 1706-1719.
216. Wang, H.; Linetsky, M.; Guo, J.; Yu A. O.; Salomon, R. G. "Metabolism of 4-hydroxy-7-oxo-5-heptenoic Acid (HOHA) lactone by retinal pigmented epithelial cells", Chem Res Toxicol 2016, 29, 1198-210.
215. Guo, J.; Wang, H.; Hrinczenko, B.; Salomon, R. G. "Efficient quantitative analysis of carboxyalkylpyrrole ethanolamine phospholipids: elevated levels in sickle cell disease blood", Chem Res Toxicol 2016, 29, 1187-97.
214. Biswas, S.; Xin, L.; Panigrahi, S.; Zimman, A.; Wang, H.; Yakubenko, V.; Byzova, T. V.; Salomon, R. G.; Podrez, E. A. "Novel phosphatidylethanolamine derivatives accumulate in circulation in hyperlipidemic ApoE-/- mice and activate platelets via TLR2", Blood 2016, 127, 2618-2629.
213. Kim, Y. W.; Yakubenko, V. P.; West, X. Z.; Gugiu, G. B.; Kutralanathan, R.; Biswas, S.; Gao, D.; Crabb, J. W.; Salomon, R. G.; Podrez, E.; Byzova, T. "Receptor-mediated mechanism controlling tissue levels of bioactive lipid oxidation products", Circ Res 2015, 117, 321-332. Journal Issue Cover
212. Salomon, R. G.; Bi, W. "Isolevuglandin adducts in disease", Antioxidants & redox signaling 2015, 22, 1703-18.
211. Wang, H.; Linetsky, M.; Guo, J.; Choi, J.; Hong, L.; Chamberlain, A. S.; Howell, S. J.; Howes, A. M.; Salomon, R. G. "4-Hydroxy-7-oxo-5-heptenoic Acid (HOHA) lactone is a biologically active precursor for the generation of 2-(w-carboxyethyl)pyrrole (CEP) derivatives of proteins and ethanolamine phospholipids", Chem Res Toxicol 2015, 28, 967-77.
210. H. Wang, J. Guo, X. Z. West, H. K. Bid, L. Lu, L. Hong, G. F. Jang, L. Zhang, J. W. Crabb, M. Linetsky and R. G. Salomon "Detection and biological activities of carboxyethylpyrrole ethanolamine phospholipids (CEP-EPs)", Chem Res Toxicol 2014, 27, 2015-22. Journal Issue Cover
209. Saeed, A. M., Duffort, S., Ivanov, D., Wang, H., Laird, J. M., Salomon, R. G., Cruz-Guilloty, F., and Perez, V. L. "The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages" PloS one 2014, 9, e106421.
208. Bakhautdin, B., Das, D., Mandal, P., Roychowdhury, S., Danner, J., Bush, K., Pollard, K., Kaspar, J. W., Li, W., Salomon, R. G., McMullen, M. R., and Nagy, L. E. "Protective role of HO-1 and carbon monoxide in ethanol-induced hepatocyte cell death and liver injury in mice" Journal of hepatology 2014, 61, 1029-37.
207. Cruz-Guilloty, F., Saeed, A. M., Duffort, S., Cano, M., Ebrahimi, K. B., Ballmick, A., Tan, Y., Wang, H., Laird, J. M., Salomon, R. G., Handa, J. T. and Perez, V. L."T Cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration" PloS one 2014, 9, e88201.
206. Renganathan, K., Gu, J., Rayborn, M. E., Crabb, J. S., Salomon, R. G., Collier, R. J., Kapin, M. A., Romano, C., Hollyfield, J. G., Crabb, J. W. "CEP biomarkers as potential tools for monitoring therapeutics" PloS one 2013, 8, e76325.
205. Charvet, C. D., Saadane, A., Wang, M., Salomon, R. G., Brunengraber, H., Turko, I. V., Pikuleva, I. A. "Pretreatment with pyridoxamine mitigates isolevuglandin-associated retinal effects in mice exposed to bright light", J Biol Chem 2013, 288, 29267-80.
204. Cruz-Guilloty, F., Saeed, A. M. Echegaray, J. J., Duffort, S., Ballmick, A., Tan, Y., Betancourt, M., Viteri, E., Ramkhellawan, G. C., Ewald, E., Feuer, W., Huang, D., Wen, R., Hong, L., Wang, H., Laird, J. M., Sene, A., Apte, R. S., Salomon, R. G., Hollyfield, J. G. and Perez, V. L. "Infiltration of proinflammatory M1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration", Int J Inflam 2013, PDF.
203. Charvet, C. D., Laird, J., Xu, Y., Salomon, R. G. and Pikuleva, I. A. "Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1", J Lipid Res 2013, 54, 1421-9.
202. Panigrahi, 1.	S., Ma, Y., Hong, L., Gao, D., West, X. Z., Salomon, R. G., Byzova, T. V. and Podrez, E. A. "Engagement of platelet toll-like receptor 9 by novel endogenous ligands promotes platelet hyperreactivity and thrombosis", Circ Res 2013, 112, 103-12.
201. Harris, S. R., Zhang, G., Sadhukhan, S., Wang, H., Shi, C., Puchowicz, M. A., Anderson, V. E., Salomon, R. G., Tochtrop, G. P., Brunengraber, H. "Metabolomics and mass isotopomer analysis as a strategy for pathway discovery: Pyrrolyl and cyclopentenyl derivatives of the pro-drug of abuse, levulinate" Chem Res Toxicol 2013, 26, 213-20.
200. Salomon, R. G. "Levuglandins: finding lipid super glue in vivo" ASBMB Today 2012, November, 34-35.
199. Salomon, R. G. "Structural Identification and Cardiovascular Activities of Oxidized Phospholipids" Circ. Res 2012, 111, 930-946.
198. Doyle, S. L., Campbell, M., Ozaki, E., Salomon, R. G., Mori, A., Kenna, P. F., Farrar, G. J., Kiang, A. S., Humphries, M. M., Lavelle, E. C., O'Neill, L. A., Hollyfield, J. G., and Humphries, P. "NLRP3 has a protective role in age-related macular degeneration through the induction of IL-18 by drusen components", Nature Med 2012, 18, 791-8.
197. Gu, X., Zhang, W., Salomon, R. G. "Fragmentation of β-Hydroxy Hydroperoxides", J Org Chem 2012, 77, 1554-9.
196. Poliakov, E., Gubin, A., Laird, J., Gentleman, S., Salomon, R. G., Redmond, T. M. "The Mechanism of Fenretinide (4-HPR) Inhibition of beta-carotene Monooxygenase 1. New Suspect for the Visual Side Effects of Fenretinide", Adv Exp Med Biol 2012, 723, 167-74.
195. Gu, X., Salomon, R.G. "Fragmentation of a Linoleate-derived γ-Hydroperoxy-α,β-unsaturated Epoxide to γ-Hydroxy- and γ-Oxo-alkenals Involves a Unique Pseudo Symmetrical Diepoxycarbinyl Radical" Free Rad Biol Med2012, 52, 601-6.
194. Salomon, R. G., Hong, L. and Hollyfield, J. G. Discovery of Carboxyethylpyrroles (CEPs): Critical Insights into AMD, Autism, Cancer, and Wound Healing from Basic Research on the Chemistry of Oxidized Phospholipids. Chem Res Toxicol 2011, 24, 1803-1816.
193. Salomon, R. G. and Gu, X. Critical Insights into Cardiovascular Disease from Basic Research on the Oxidation of Phospholipids: The g-Hydroxyalkenal Phospholipid Hypothesis. Chem Res Toxicol 2011, 24, 1791-1802.
192. Charvet, C., Liao, W. L., Heo, G. Y., Laird, J., Salomon, R. G., Turko, I. V. and Pikuleva, I. A. Isolevuglandins and mitochondrial enzymes in the retina: mass spectrometry detection of post-translational modification of Sterol-metabolizing CYP27A1. J Biol Chem 2011, 286, 20413–22.
191. Gu, X., Choi, J., Li, W., Chen, X., Laird, J., and Salomon, R.G. An 1O2 Route to γ-Hydroxyalkenal Phospholipids by Vitamin E Induced Fragmentation of Hydroperoxydiene-derived Endoperoxides. Chem Res Toxicol 2011, 24, 1080-1093.
Choi, J., Zhang, W., Gu, X., Chen, X., Hong, L., Laird, J. M. and Salomon, R. G. Lysophosphatidylcholine is Generated by Spontaneous Deacylation of Oxidized Phospholipids. Chem Res Toxicol 2011, 24, 111-8.
Choi, J., Laird, J. M. and Salomon, R. G. An efficient synthesis of g-hydroxy-a,b-unsaturated aldehydic esters of 2-lysophosphatidylcholine. Bioorg Med Chem 2011, 19, 580-587
Kim, J., Minkler, P. E., Salomon, R. G., Anderson, V. E. and Hoppel, C. L. Cardiolipin: characterization of distinct oxidized molecular species. J Lipid Res 2010, 52, 125-135.
West, X. Z., Malinin, N. L., Merkulova, A. A., Tischenko, M., Kerr, B. A., Borden, E. C., Podrez, E. A., Salomon, R. G. and Byzova, T. V. Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands. Nature 2010, 467, 972-976.
186. Gu, J.; Pauer, G. J.; Yue, X.; Narendra, U.; Sturgill, G. M.; Bena, J.; Gu, X.; Peachey, N. S.; Salomon, R. G.; Hagstrom, S. A.; Crabb, J. W. "Proteomic and Genomic Biomarkers for Age-Related Macular Degeneration", Adv Exp Med Biol 2010, 664, 411-417.
185. Hollyfield, J. G.; Perez, V. L.; Salomon, R. G. "A hapten generated from an oxidation fragment of docosahexaenoic acid is sufficient to initiate age-related macular degeneration", Mol Neurobiol 2010, 41, 290-8.
184. Mesaros, C.; Gugiu, B. G.; Zhou, R.; Lee, S. H.; Choi, J.; Laird, J.; Blair, I. A.; Salomon, R. G. "A 13-Oxo-9,10-epoxytridecenoate phospholipid analogue of the genotoxic 4,5-epoxy-2E-decenal: detection in vivo, chemical synthesis, and adduction with DNA", Chem Res Toxicol 2010, 23, 516-27.
183. Roychowdhury, S.; McMullen, M. R.; Pritchard, M. T.; Li, W.; Salomon, R. G.; Nagy, L. E. "Formation of
g-ketoaldehyde-protein adducts during ethanol-induced liver injury in mice", Free Radic Biol Med 2009, 47,1526-38.
182. Lu, L.; Gu, X.; Hong, L.; Laird, J.; Jaffe, K.; Choi, J.; Crabb, J.; Salomon, R. G. "Synthesis and Structural Characterization of Carboxyethylpyrrole-Modified Proteins: Mediators of Age-related Macular Degeneration", Bioorg Med Chem 2009, 17, 7548-61.
181. Li, W.; Laird, J. M.; Lu, L.; Roychowdhury, S.; Nagy, L. E.; Zhou, R.; Crabb, J. W.; Salomon, R. G. "Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts", Free Radic Biol Med 2009, 47, 1539-52.
180. Gu, J.; Pauer, G. J.; Yue, X.; Narendra, U.; Sturgill, G. M.; Bena, J.; Gu, X.; Peachey, N. S.; Salomon, R. G.; Hagstrom, S. A.; Crabb, J. W. "Assessing susceptibility to age-related macular degeneration with proteomic and genomic biomarkers", Mol Cell Proteomics 2009, 8, 1338-49.
179. Govindarajan, B.; Junk, A.; Algeciras, M.; Salomon, R. G.; Bhattacharya, S. K. "Increased isolevuglandin-modified proteins in glaucomatous astrocytes", Mol Vis 2009, 15, 1079-91.
178. Chen, R.; Chen, X.; Salomon, R. G.; McIntyre, T. M. "Platelet activation by low concentrations of intact oxidized LDL particles involves the PAF receptor", Arterioscler Thromb Vasc Biol 2009, 29, 363-71.
177. Retinal pigment epithelium lipofuscin proteomics, Ng, K. P., Gugiu, B., Renganathan, K., Davies, M. W., Gu, X., Crabb, J. S., Kim, S. R., Rozanowska, M. B., Bonilha, V. L., Rayborn, M. E., Salomon, R. G., Sparrow, J. R., Boulton, M. E., Hollyfield, J. G., and Crabb, J. W., Mol Cell Proteomics 2008 7, 1397-1405.
176. Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeutics, Govindarajan, B., Laird, J., Sherman, R., Salomon, R. G., and Bhattacharya, S. K., CNS & Neurol Disorders Drug Targets 2008 7, 295-304.
175. Oxidative damage-induced inflammation initiates age-related macular degeneration, Hollyfield, J. G., Bonilha, V. L., Rayborn, M. E., Yang, X., Shadrach, K. G., Lu, L., Ufret, R. L., Salomon, R. G., and Perez, V. L.. Nature Medicine 2008, 14, 194-198.
174. Specific Oxidized Phospholipids Inhibit Scavenger Receptor BI Mediated Selective Uptakeof Cholesteryl Esters, Ashraf, M. Z., Kar, N. S., Chen, X., Choi, J., Salomon, R. G., Febbraio, M., and Podrez, E. A., J Biol Chem 2008, 283, .
173. Carboxyethylpyrrole adducts, age-related macular degeneration and neovascularization, Renganathan, K., Ebrahem, Q., Vasanji, A., Gu, X., Lu, L., Sears, J., Salomon, R. G., Anand-Apte, B., and Crabb, J. W., Adv Exp Med Biol 2008, 613, 261-267.
The Autistic Phenotype Exhibits a Remarkably Localized Modification of Brain Protein by Products of Free Radical-Induced Lipid Oxidation, Evans, T. A., Siedlak, S. L., Lu, L., Fu, X., Wang, Z., McGinnis, W. R., Fakhoury, E., Castellani, R. J., Hazen, S. L., Walsh, W. J., Lewis, A. T., Salomon, R. G., Smith, M. A., Perry, G., and Zhu, X., Am J Biotech Biochem 2008, 4, 61-72.
171. The lipid whisker model of the structure of oxidized cell membranes, Greenberg, M. E., Li, X. M., Gugiu, B. G., Gu, X., Qin, J., Salomon, R. G. and Hazen, S. L., J Biol Chem 2008, 283, 2385-2396.
170. Polyunsaturated phospholipids promote the oxidation and fragmentation of g-hydroxyalkenals: formation and reactions of oxidatively truncated ether phospholipids, Chen, X., Zhang, W., Laird, J., Hazen, S. L. and Salomon, R. G., J Lipid Res 2008,
169. Isolevuglandin-modified proteins, including elevated levels of inactive calpain-1, accumulate in glaucomatous trabecular meshwork, Govindarajan, B., Laird, J., Salomon, R. G. and Bhattacharya, S. K., Biochemistry 2008, 47, 817-25.
168. Conformation of an endogenous ligand in a membrane bilayer for the macrophage scavenger receptor CD36, Li, X. M., Salomon, R. G., Qin, J., and Hazen, S. L., Biochemistry 2007, 46, 5009-5017.
167. Serum vitamin E and oxidative protein modification in hemodialysis: a randomized clinical trial, Lu, L., Erhard, P., Salomon, R. G., and Weiss, M. F., Am J Kidney Dis 2007, 50, 305-313.
166. Platelet CD36 links hyperlipidemia, oxidant stress and a prothrombotic phenotype, Podrez, E. A., Byzova, T. V., Febbraio, M., Salomon, R. G., Ma, Y., Valiyaveettil, M., Poliakov, E., Sun, M., Finton, P.J., Curtis, B.R., Chen, J., Zhang, R., Silverstein, R.L., and Hazen, S.L., Nature Medicine 2007, 13, 1086-1095.
165. Fe(2+) Catalyzes Vitamin E-Induced Fragmentation of Hydroperoxy and Hydroxy Endoperoxides That Generates g-Hydroxy Alkenals,Gu, X., Zhang, W., and Salomon, R. G. J. Am. Chem. Soc. 2007, 129, 6088-6089.
Preparative singlet oxygenation of linoleate provides doubly allylic dihydroperoxides: putative intermediates in the generation of biologically active aldehydes in vivo, Zhang, W., Sun, M. and Salomon, R. G., 2006, J Org Chem 71, 5607-5615.
163. A role for neutral sphingomyelinase activation in the inhibition of LPS action by phospholipid oxidation products. Journal of lipid research, Walton, K. A., Gugiu, B. G., Thomas, M., Basseri, R. J., Eliav, D. R., Salomon, R. G. and Berliner, J. A., 2006, 47, 1967-1974.
162. Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions., Sun, M., Finnemann, S. C., Febbraio, M., Shan, L., Annangudi, S. P., Podrez, E. A., Hoppe, G., Darrow, R., Organisciak, D. T., Salomon, R. G., Silverstein, R. L. and Hazen, S. L., 2006, J Biol Chem, 281, 4222-4230.
161. Identification of oxidatively truncated ethanolamine phospholipids in retina and their generation from polyunsaturated phosphatidylethanolamines., Gugiu, B. G., Mesaros, C. A., Sun, M., Gu, X., Crabb, J. W. and Salomon, R. G., 2006, Chem Res Toxicol 19, 262-271.
160. Phospholipid hydroxyalkenals, a subset of recently discovered endogenous CD36 ligands, spontaneously generate novel furan-containing phospholipids lacking CD36 binding activity in vivo,Gao, S., Zhang, R., Greenberg, M. E., Sun, M., Chen, X., Levison, B. S., Salomon, R. G. and Hazen, S. L., 2006, J. Biol. Chem. 281, 31298-308.
159. Carboxyethylpyrrole oxidative protein modifications stimulate neovascularization: Implications for age-related macular degeneration,.Ebrahem, Q., Renganathan, K., Sears, J., Vasanji, A., Gu, X., Lu, L., Salomon, R. G., Crabb, J. W. and Anand-Apte, B., 2006, PNAS, 103, 13480-4.
An Efficient Synthesis of 4-Oxo-alkenoic Acids from 2-Alkylfurans, Annangudi,.S.P, Sun, M., Salomon, R.G. Syn Let, 2005.
Oxidized Phospholipids, Isolevuglandins and Atherosclerosis, Zhang, W., Salomon, R.G. Mol Nutr Food Res, 2005, 49, 1050-62.
Cochlin deposits in the trabecular meshwork of the glaucomatous DBA/2J mouse, Bhattacharya, S. K., Annangudi, S. P., Salomon, R. G., Kuchtey, R. W., Peachey, N. S. Crabb, J. W. Exp Eye Res 2005, 80, 741-4.
Isolevuglandins, Oxidatively Truncated Phospholipids and Atherosclerosis, Salomon, R. G., Ann NY Acad Sci 2005, 1043, 327-42.
Distinguishing levuglandins produced through the cyclooxygenase and isoprostane pathways, Salomon, R. G. Chem Phys Lipids 2005, 134, 1-20.
Levuglandins and Isolevuglandins: Stealthy Toxins of Oxidative Injury, Salomon, R. G. Antiox. Redox Signal 2005, 7, 185-201.
Proteomic approaches to understanding age-related macular degeneration, Hollyfield, J. G.; Salomon, R. G.; Crabb, J. W. in Retinal Degenerations: Mechnisms and Experimental Therapy; R. E. Anderson, Ed.; Kluwer Academic Pub: San Diego, 2004; pp 83-90.
Iso[7]LGD2-protein adducts are abundant in vivo and free radical-induced oxidation of an arachidonyl phospholipid generates this D series isolevuglandin in vitro, Poliakov, E.; Meer, S. G.; Roy, S. C.; Mesaros, C.; Salomon, R. G. Chem Res Toxicol 2004, 17, 613-22.
g-Hydroxyalkenals Are Oxidatively Cleaved through Michael Addition of Acylperoxy Radicals and Fragmentation of Intermediate b-Hydroxyperesters, Balamraju, Y. N.; Sun, M.; Salomon, R. G. J Am Chem Soc 2004, 126, 11522-8.
Oxidative fragmentation of hydroxy octadecadienoates generates biologically active g-hydroxyalkenals, Sun, M.; Salomon, R. G. J Am Chem Soc 2004, 126, 5699-708.
Total Syntheses of Bioactive Oxidized Ethanolamine Phospholipids, Gugiu, B. G., and Salomon, R. G. Org Lett 2003, 5, 2797-2799.
147. Oxidatively Truncated Docosahexaenoate Phospholipids: Total Synthesis, Generation, and Peptide Adduction Chemistry, Gu, X.; Sun, M.; Gugiu, B.; Hazen, S.; Crabb, J. W.; Salomon, R. G. J Org Chem 2003, 68, 3749-3761.
146. Carboxyethylpyrrole Protein Adducts and Autoantibodies, Biomarkers for Age-related Macular Degeneration, Gu, X.; Meer, S. G.; Miyagi, M.; Rayborn, M. E.; Hollyfield, J. G.; Crabb, J. W.; Salomon, R. G. J Biol Chem 2003, 278, 42027-35.
Isolevuglandins, a novel class of isoprostenoid derivatives, function as integrated sensors of oxidant stress and are generated by myeloperoxidase in vivo. Poliakov, E., Brennan, M.L., Macpherson, J., Zhang, R., Sha, W., Narine, L., Salomon, R.G., and Hazen, S.L. Faseb J 2003, 17, 2209-2220.
Phospholipid hydroxyalkenals: biological and chemical properties of specific oxidized lipids present in atherosclerotic lesions, Hoff, H. F., O'Neil, J., Wu, Z., Hoppe, G., and Salomon, R. L. Arterioscler Thromb Vasc Biol 2003, 23, 275-82.
Drusen proteome analysis: an approach to the etiology of age-related macular degeneration, Crabb, J. W.;Miyagi, M.;Gu, X.;Shadrach, K.;West, K. A.;Sakaguchi, H.;Kamei, M.;Hasan, A.;Yan, L.;Rayborn, M. E.;Salomon, R. G. and Hollyfield, J. G., Proc Natl Acad Sci U S A 2002, 99, 14682-7.
A Novel Family of Atherogenic Oxidized Phospholipids Promotes Macrophage Foam Cell Formation via the Scavenger Receptor CD36 and Is Enriched in Atherosclerotic Lesions, Podrez, E. A.;Poliakov, E.;Shen, Z.;Zhang, R.;Deng, Y.;Sun, M.;Finton, P. J.;Shan, L.;Febbraio, M.;Hajjar, D. P.;Silverstein, R. L.;Hoff, H. F.;Salomon, R. G. and Hazen, S. L., J Biol Chem 2002, 277, 38517-23.
Identification of a Novel Family of Oxidized Phospholipids That Serve as Ligands for the Macrophage Scavenger Receptor CD36, Podrez, E. A.;Poliakov, E.;Shen, Z.;Zhang, R.;Deng, Y.;Sun, M.;Finton, P. J.;Shan, L.;Gugiu, B.;Fox, P. L.;Hoff, H. F.;Salomon, R. G. and Hazen, S. L., J Biol Chem 2002, 277, 38503-16.
Preservation of cardiolipin content during aging in rat heart interfibrillar mitochondria, Moghaddas, S.;Stoll, M. S.;Minkler, P. E.;Salomon, R. G.;Hoppel, C. L. and Lesnefsky, E. J., J Gerontol A Biol Sci Med Sci 2002, 57, B22-8.
Hydroxy alkenal phospholipids regulate inflammatory functions of endothelial cells, Subbanagounder, G.;Deng, Y.;Borromeo, C.;Dooley, A. N.;Berliner, J. A. and Salomon, R. G., Vascular Pharmacology 2002, 38, 201-09.
Novel bioactive phospholipids: practical total syntheses of products from the oxidation of arachidonic and linoleic esters of 2-lysophosphatidylcholine(1), Sun, M.;Deng, Y.;Batyreva, E.;Sha, W. and Salomon, R. G., J Org Chem 2002, 67, 3575-84.
Total synthesis of 17-isoLevuglandin E4 and the structure of C22-PGF4a. Sha, W. and Salomon, R. G., J Org Chem 2000, 65, 5315-26.
Isolevuglandin-protein adducts in humans: products of free radical-induced lipid oxidation through the isoprostane pathway. Salomon, R. G., Batyreva, E., Kaur, K., Sprecher, D. L., Schreiber, M. J., Crabb, J. W., Penn, M. S., DiCorleto, A. M., Hazen, S. L. and Podrez, E. A., Biochim Biophys Acta 2000, 1485, 225-35.
HNE-derived 2-pentylpyrroles are generated during oxidation of LDL, are more prevalent in blood plasma from patients with renal disease or atherosclerosis, and are present in atherosclerotic plaques. Salomon, R. G., Kaur, K., Podrez, E., Hoff, H. F., Krushinsky, A. V. and Sayre, L. M., Chem Res Toxicol 2000, 13, 557-64.
Isolevuglandin-protein adducts in oxidized low density lipoprotein and human plasma. A strong connection with cardiovascular disease. Salomon, R. G., Kaur, K. and Batyreva, E., Trends Cardiovasc Med 2000, 10 53-9.
Total synthesis of oxidized phospholipids. 3. The (11E)-9-hydroxy-13-oxotridec-11-enoate ester of 2-lysophosphatidylcholine. Deng, Y. and Salomon, R. G., J Org Chem 2000, 65, 6660-5.
Formation of reactive products of the isoprostane pathway: isolevuglandins and cyclopentenone isoprostanes. Roberts, L. J., Brame, C. J., Chen, Y., Morrow, J. D. and Salomon, R. G., Adv Exp Med Biol 1999, 469, 335-341.
Leukocytes utilize myeloperoxidase-generated nitrating intermediates as physiological catalysts for the generation of biologically active oxidized lipids and sterols in serum, Schmitt, D.; Shen, Z; Zhang, R.; Colles, S. M.; Wu, W.; Salomon, R. G.; Chen, Y.; Chisolm, G. M.; Hazen, S. L., Biochem. 1999, 38, 16904-16915.
New developments in the isoprostane pathway: identification of novel highly reactive g-ketoaldehydes (isolevuglandins) and characterization of their protein adducts, Roberts, L. J., II; Salomon, R. G.; Morrow, J. D.; Brame, C. J., FASEB J. 1999, 13, 1157-1168.
Total Synthesis of Iso[7]-Levuglandin D2, Roy, S. C.; Nagarajan, L.; Salomon, R. G., J. Org. Chem. 1999, 64, 1218-1224.
Characterization of lysyl adducts formed from prostaglandin H2 via the levuglandin pathway, Boutaud, O.; Brame, C. J.; Salomon, R. G.; Roberts, II, L. J.; Oates, J. A. Biochem. 1999, 38, 9389-9396.
Protein adducts of iso[4]levuglandin E2, a product of the isoprostane pathway, in oxidized low density lipoprotein, Salomon, R. G.; Sha, W.; Brame, C.; Kaur, K.; Subbanagounder, G.; O'Neil, J.; Hoff, H.F.; Roberts II, L. J. J. Biol. Chem. 1999, 274, 20271-20280.
Identification of extremely reactive g-ketoaldehydes (isolevuglandins) as products of the isoprostane pathway and characterization of their lysyl protein adducts, Brame, C.; Salomon, R. G.; Morrow, J. D.; Roberts II, L. J. J. Biol Chem. 1999, 274, 13139-13146.
Total Synthesis of g-Hydroxy-a,b-unsaturated Esters of Cholesterol and 2-Lysophosphatidylcholine, Deng, Y.; Salomon, R. G. J. Org. Chem. 1998, 63, 7789-7794.
Advanced lipid peroxidation end-products in Alexander's disease, Castellani, R. J.; Perry, G.; Harris, P. L.; Cohen, M. L.; Sayre, L. M.; Salomon, R. G.; Smith, M. A., Brain Res. 1998, 787, 15-18.
Synthesis of [9-3H]-trans-4-Hydroxy-2-nonenal, Deng, Y.; Salomon, R. G., J. Org. Chem. 1998, 63, 3504-3507.
Measurement of oxidation in plasma Lp(a) in CAPD patients using a novel ELISA, Podrez, E. A.; O'Neil, J.; Salomon, R. G.; Schreiber, M. J.; Hoff, H. F., Kidney Int. 1998, 54, 637-645.
Carboxyalkyl Pyrroles in Human Plasma and Oxidized Low Density Lipoproteins, Kaur, K.; Salomon, R. G.; O'Neil, J.; Hoff, H. F. Chem. Res. Toxicol. 1997, 10, 1387-1396.
Total Synthesis of iso[4]-Levuglandin E2, Subbanagounder, G., Salomon, R. G., Murthi, K. K., Brame, C., Roberts, L. J., III, J. Org. Chem. 1997, 62, 7658-7666.
Oxidation of Low Density Lipoproteins Produces Levuglandin-protein Adducts, Salomon, R. G., Subbanagounder, G., Singh, U., O'Neil, J., Hoff, H. F., Chem. Res. Toxicol. 1997, 10,750-759.
Structural Identification by Mass Spectrometry of Oxidized Phospholipids in Minimally Oxidized Low Density Lipoprotein that Induce Monocyte/Endothelial Interactions and Evidence for Their Presence In Vivo, Watson, A. D., Leitinger, N., Navab, M., Faull, K. F., Hörkkö, S., Witztum, J. L., Palinski, W., Schwenke, D., Salomon, R. G., Sha, W., Subbanagounder, G., Fogelman, A. M., Berliner, J. A. J. Biol. Chem. 1997, 272, 13597-13607.
Levuglandin E2-Protein Adducts in Human Plasma and Vasculature, Salomon, R. G., Subbanagounder, G., O'Neil, J., Kaur, K., Smith, M. A., Hoff, H. F., Perry, G., Monnier, V. M. Chem. Res. Toxicol. 1997, 10, 536-545.
4-Hydroxynonenal-Derived Advanced Lipid Peroxidation End Products are Increased in Alzheimer's Disease, Sayre, L. M., Zelasko, D. A., Harris, P. L. R.,. Perry, G., Salomon, R. G., Smith, M. A. J. Neurochem. 1997, 68, 2092-7.
Macrophage Recognition of LDL Modified by Levuglandin E2, an Oxidation Product of Arachidonic Acid, Hoppe, G., Subbanagounder, G., O'Neil, J., Salomon, R. G., Hoff, H. F. Biochim. Biophys. Acta 1997, 1344, 1-5.
Immunochemical Evidence Supporting 2-Pentylpyrrole Formation on Proteins Exposed to 4-Hydroxy-2-nonenal, Sayre, L. M., Sha, W., Xu, G., Kaur, K., Nadkarni, D., Subbanagounder, G., Salomon, R. G. Chem. Res. Toxicol. 1996, 9, 1194-1201.
Copper(I) Trifluoromethanesulfonate, Salomon, R. G. in "Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A. Ed., 1995
Bis(tributyltin) Peroxide, Salomon, R. G. in "Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A. Ed., 1995
Di-t-butylmethylsilyl Trifluoromethanesulfonate, Salomon, R. G. in "Encyclopedia of Reagents for Organic Synthesis", Paquette, L. A. Ed., 1995
Formation and Stability of Pyrrole Adducts in The Reaction of Levuglandin E2 with Proteins, DiFranco, E., Subbanagounder, G., Kim, S., Murthi, K., Taneda, S., Monnier, V. M., Salomon, R. G. Chem Res Toxicol 1995, 8, 61-7.
Synthesis of a Pyrazole Isostere of Pyrroles formed by the Reaction of the e-Amino Groups of Protein Lysyl Residues with Levuglandin E2, Kobierski, M. E., Kim. S., Murthi, K. K., Iyer, R. S., Salomon R. G., J. Org. Chem. 1994, 59, 6044-6050.
Generation of Pyrroles in The Reaction of Levuglandin E2 with Proteins, Iyer, R. S., Kobierski, M. E., Salomon, R. G., J. Org. Chem. 1994, 59, 6038-6043.
A Short Synthesis of the Antimitotic Allylic Diepoxide Functional Array of Spatol, Murthi, K. K. Salomon, R. G. Tetrahedron Lett. 1994, 35, 517-520.
Total Synthesis of Halichondrin B from Common Sugars: an F-ring Intermediate from D-Glucose and Efficient construction of the C1 to C21 Segment, Cooper, A. J.; Pan, W.; Salomon, R. G. Tetrahedron Lett. 1993, 34, 8193-8196.
Total Synthesis of Halichondrins: Enantioselective Construction of a Homochiral Tetracyclic KLMN-ring Intermediate from D-Mannitol DiFranco, E.; Ravikumar, V. T.; Salomon, R. G. Tetrahedron Lett. 1993, 34, 3247.
Formation of DNA-Protein Cross-Links in Mammalian Cells by Levuglandin E2, Murthi, K. K.; Friedman, L. R.; Oleinick, N. L.; Salomon, R. G. Biochem. 1993, 32, 4090.
Pyrrole Formation from 4-Hydroxynonenal and Primary Amines, Sayre, L. M.; Arora, P. K.; Iyer, R. S.; Salomon, R. G. Chem. Res. Toxicol., 1993, 6, 19.
Homogeneous Metal Catalyzed Photochemistry in Organic Synthesis, Salomon, R. G.: Ghosh S.; Raychaudhuri, S. in Photosensitive Metal-Organic Systems: Mechanistic Principles and Recent Applications, ACS Advances in Chemistry Series, 238, Kutal, C. and Serpone, N. Eds., 315, 1993.
Brain Tissue Injury and Blood-Brain Barrier Opening Induced by Injection of LGE2 or PGE2, Schmidley, J. W.; Dadson, J.; Iyer, R. S.; Salomon, R. G. Prostaglandins Leukotrienes and Essential Fatty Acids 1992, 47, 105.
Physiological Evidence for The Possible Existence of Anhydrolevuglandin E2-like Activity in Extracts and Media from Uteri of Rats, Foreman, D.; Parker III, C.; Alonzo, I.; Salomon, R. G. Prostaglandins 1992, 43, 573.
Evidence That The Prostaglandin E2 Receptor and the Anhydrolevuglandin E2 Receptor in The Rat Uterus Are The Same Receptor, Foreman, D.; Salomon, R. G. Prostaglandins 1992, 43, 263.
Synthesis of a Cancer Growth Inhibiting Diterpene: Spatol, Salomon, R. G. in Strategies and Tactics in Organic Synthesis, 3, 381-416, Lindberg, T. (Ed.), Academic Press, Orlando, Florida, 1991
Total Synthesis of Spatol and Other Spatane Diterpenes, Salomon, R. G.; Basu, B.; Roy, S.; Sachinvala, N. D. J. Am. Chem. Soc. 1991, 113, 3096.
Total Synthesis of Spatane Diterpenes: The Tricyclic Nucleus, Salomon, R. G.; Sachinvala, N. D.; Roy, S.; Basu, B.; Raychaudhuri, S. R.; Miller, D. B.; Sharma, R. B. J. Am. Chem. Soc. 1991, 113, 3083.
Electrophilic Levuglandin E2-Protein Adducts Bind Glycine: A Model for Protein Cross-linking, Jirousek, M. R.; Murthi, K. K.; Salomon, R. G. Prostaglandins 1990, 40, 187.
Levuglandin E2 Inhibits Mitosis and Microtubule Assembly, Murthi, K.; Salomon, R. G.; Sternlicht, H.; Prostaglandins 1990, 39, 611.
Total Synthesis of Halichondrins: Enantioselective Construction of a Homochiral Pentacyclic C1-C15 Intermediate from D-Ribose, Cooper, A. J.; Salomon, R. G. Tetrahedron Lett. 1990, 31, 3813.
Decomposition of Levuglandin E2. Dehydration and Allylic Rearrangement Products, Iyer, R. S.; Miller, D. B.; Salomon, R. G. J. Org. Chem. 1990, 55, 3175.
Levuglandin E2: Enantiocontrolled Total Synthesis of a Biologically Active Rear-range-ment Product from the Prostaglandin Endoperoxide PGH2, Miller, D. B.; Raychaudhuri, S. R.; Avasthi, K.; Lal, K.; Levison, B.; Salomon, R. G. J. Org. Chem. 1990, 55, 3164.
Total Synthesis of Halichondrins: Highly Stereoselective Construction of a Homochiral Pentasubstituted H-Ring Pyran Intermediate from a-D-Glucose, Kim, S.; Salomon, R. G. Tetrahedron Lett. 1989, 30, 6279.
6-Substituted Bicyclo[2.2.1]hept-5-en-2-one Ketals, Lal, K.; Salomon, R. G.J. Org. Chem. 1989, 54, 2628.
Total Synthesis of (+)-Spatol. A Stereospecific Construction of Vicinal Diepoxides from 2,3-Epoxy-1,4-diols, Salomon, R. G.; Basu, B.; Roy, Subhas; Sharma, Ram. B.Tetrahedron Lett. 1989, 30, 4621.
A Total Synthesis Establishes the Correct Structures of Robustadials A and B, Salomon, R.G.; Mazza, S.M.; Lal, K.J. Org. Chem. 1989, 54, 1562.
Total Synthesis of Robustadial A and B Methyl Ethers, Salomon, R.G.; Lal, K.; Mazza, S.M.; Zarate, E.A.; Young, W.J. J. Am. Chem. Soc. 1988, 110, 5213.
Levuglandin E2 Crosslinks Proteins, Iyer, R.S.; Ghosh, S.; Salomon, R.G. Prostaglandins 1989, 37, 471.
Purification of a Water-Sensitive Natural Product with an Aprotic CPC Solvent System, Jirousek, M.R.; Salomon, R.G. J. Liq. Chrom. 1988, 11, 2507.
Anhydrolevuglandin D2 Inhibits the Uterotonic Activity ofProstaglandins F2a and D2, Foreman, D.; Levison, B.S.; Miller, D.B.; Salomon, R.G. Prostaglandins 1988, 35, 115.
Oxidative Bisdecarboxylation of Alkoxymalonic Acids with Cerium(IV), Salomon, R.G.; Roy, S.; Salomon, M.F. Tetrahedron Lett. 1988, 29, 769.
Robustadials. 4. Molecular Mechanics and NMR Studies of Conformational and Configurational Equilibria: 3,4-Dihydrospiro[2H-1-benzopyran-2,2'-bicyclo-[2.2.1]-hept-anes], Jirousek, M.J.; Mazza, S.M.; Salomon, R.G. J. Org. Chem., 1988, 53, 3688.
Robustadials. 3. Total Synthesis of Camphane Analogs, Mazza, S.M.; Lal, K.; Salomon, R.G. J. Org. Chem., 1988, 53, 3681.
Robustadials 2. Total Synthesis of the Bicyclo[3.2.0]heptane Structure Proposed for Robustadials A and B, Lal, K.; Zarate, E.A.; Youngs, W.J.; Salomon, R.G. J. Org. Chem., 1988, 53, 3673.
Prostaglandin Endoperoxides. 21. Covalent Binding of Levuglandin E2 with Proteins, Salomon, R.G.; Jirousek, M.B.; Ghosh, S.; Sharma, R.B. Prostaglandins, 1987, 34, 643.
Effects of E2 Levuglandins on the Contractile Activity of the Rat Uterus, Foreman, D.; Zuk, L.; Miller, D.B.; Salomon, R.G. Prostaglandins 1987, 34, 91.
Hydroxyl-Directed Regioselective Monodemethylation of Polymethoxy Arenes, Lal, K.; Ghosh, S.; Salomon, R.G. J. Org. Chem. 1987, 52, 1072.
A Synthesis of Cyclobutanated Butyrolactones via Copper(I)-Catalyzed Intermo-lec-ular Photocycloadditions of Homoallyl Vinyl or Diallyl Ethers, Ghosh, S.; Raychaudhuri, S.R.; Salomon, R.G. J. Org. Chem. 1987, 52, 83.
A Cu(I)-Catalyzed Photobicyclization Route to Exo-1,2-Polymethylene and 7-Hydroxy Norbornanes. Nonclassical 2-Bicyclo[3.2.0]heptyl and 7-Norbornyl Carbenium Ion Intermediates, Avasthi, K.; Salomon, R.G. J. Org. Chem. 1986, 51, 2556.
Regiospecific Synthesis of b,g-Unsaturated Ketones from Allylic Acohols. Claisen Rearrangement of a-Allyloxyketone Enol Derivatives, Kachinsky, J.L.C.; Salomon, R.G. J. Org. Chem. 1986, 51, 1393.
Total Synthesis Necessitates Revision of the Structure of Robustadials, Lal, K.; Zarate, E.A.; Youngs, W.J.; Salomon, R.G. J. Am. Chem. Soc. 1986, 108, 1311.
Di-tert-butyldimethylsilyl (DTBMS) Trifluoromethanesulfonate. Preparation and Synthetic Applications of DTBMS Esters and Enol Ethers, Bhide, R.S.; Levison, B.S.; Sharma, R.B.; Ghosh, S.; Salomon, R.G. Tetrahedron Lett. 1986, 27, 671.
Oxygen-17 Nuclear Magnetic Resonance Chemical Shifts of Dialkyl Peroxides: Large Conformational Effects, Zagorski, M.G.; Allan, D.S.; Salomon, R.G.; Clennan, E.L.; Heah, P.C.; L'Esperance, R.P.;J. Org. Chem. 1985, 50, 4484.
Prostaglandin Endoperoxide Reaction Mechanisms and the Discovery of Levuglandins, Salomon, R.G. Accounts Chem. Res. 1985, 18, 294.
Levuglandins: Isolation, Characterization and Total Synthesis of New Secoprostanoid Products from Prostaglandin Endoperoxides, Salomon, R.G.; Miller, D.B. Adv. Prostaglandin Thrombox. Leuko. Res. 1985, 15, 323.
Total Synthesis of Anhydro Levuglandin D2, ; Levison, B.S.; Miller, D.B.; Salomon, R.G. Tetrahedron Lett. 1984, 25, 4633.
Asymmetric Total Synthesis of Levuglandin E2, Salomon, R.G.; Miller, D.B.; Raychau-dhuri, S.R.; Avasthi, K.; Lal, K.; Levison, B.S. J. Am. Chem. Soc. 1984, 106, 8296.
Synthesis of Bicylic Vinylcyclobutanes via Copper(I) Catalyzed Intramolecular 2p +2p Photocycloadditions of Conjugated Dienes to Alkenes, Avasthi, K.; Raychaudhuri, S.R.; Salomon, R.G. J. Org. Chem. 1984, 49, 4322.
Convenient Preparation of N,N-Dimethylacetamide Dimethyl Acetal, Salomon, R.G.; Raychaudhuri, S. J. Org. Chem. 1984, 49, 3659.
Solvent Induced Fragmentation of Prostaglandin Endoperoxides. New Aldehyde Products from PGH2 and a Novel Intramolecular 1,2-Hydride Shift During Endoperoxide Fragmentation in Aqueous Solution, Salomon, R.G.; Miller, D.B.; Zagorski, M.G.; Coughlin, D.J. J. Am. Chem. Soc. 1984, 106, 6049.
Synthesis of Multicyclic Pyrrolidines via Copper(I) Catalyzed Photobicyclization of Ethyl N,N-Diallyl Carbamates, Salomon, R.G.; Ghosh, S.; Raychaudhuri, S. Miranti, T.S. Tetrahedron Lett. 1984, 25, 3167.
Selectivity and Catalysis in Ene Reactions of Diethyl Oxomalonate, Salomon, M.F.; Pardo, S.N.; Salomon, R.G. J. Org. Chem. 1984, 49, 2446.
Enecarboxylation with Diethyl Oxomalonate as an Enophilic Equivalent of Carbon Dioxide. A Synthesis of Allylcarboxylic Acids, Salomon, M.F.; Pardo, S.N.; Salomon, R.G. J. Am. Chem. Soc. 1984, 106, 3797.
Copper(I) Catalyzed Photocycloaddition: 3,3-Dimethyl-cis-Bicyclo[3.2.0]heptan-2-one, Salomon, R.G.; Ghosh, S. Org. Syn. 1984, 62, 125.
Stereocontrol of Michael Hydride Reduction by a Remote Hydroxyl Group. A Strategy for Stereorational Total Synthesis of Spatane Diterpenes. Salomon, R.G.; Sachinvala, N.D.; Raychaudhuri, S.R.; Miller, D.B. J. Am. Chem. Soc. 1984, 106, 1750.
Base Catalyzed Fragmentation of 2,3-Dioxabicyclo[2.2.1]heptane, the Bicyclic Peroxide Nucleus of Prostaglandin Endoperoxides: Large Secondary Deuterium Kinetic Isotope Effects, Zagorski, M.G.; Salomon, R.G. J. Am. Chem. Soc. 1984, 106, 1750.
Application of 2-Dimensional FTNMR to the Relative Configurational Assignment of 8-Methyl-4-oxo-10-trimethylsiloxy pentacyclo[7.2.1.0, O]dodecane-10-carbo-nitrile, Rinaldi, P.L.; Salomon, R.G. J. Org. Chem. 1983, 48, 3182.
Homogeneous Metal Catalysis in Organic Photochemistry, Salomon, R.G. Tetrahedron 1983, 39, 485.
Copper(I) Catalysis of Olefin Photoreactions. 11. Synthesis of Multicyclic Furans and Butyrolactones via Photobicyclization of Homoallyl Vinyl and Diallyl Esters, Raychaudhuri, S.R.; Ghosh, S.; Salomon R.G. J. Am. Chem. Soc. 1982, 104, 6841.
Ester Enolates from a-Acetoxy Esters. Synthesis of Aryl Malonic and a-Aryl Alkonic Esters from Aryl Nucleophiles and a-Keto Esters, Ghosh, S.; Pardo, S.N.; Salomon, R.G. J. Org. Chem. 1982, 47, 4692.
Prostaglandin Endoperoxides. 12. Carboxylate Catalysis and the Effects of Proton Donors on the Decomposition of 2,3-Dioxabicyclo[2.2.1]heptane, Zagorski, M.G.; Salomon, R.G. J. Am. Chem. Soc. 1982, 104, 3498.
Total Synthesis Refutes the Postulated Structure of Leucogenenol, Salomon, R.G.; Ghosh, S.; Zagorski, M.G.; Reitz, M. J. Am. Chem. Soc. 1982, 104, 1008.
Copper(I) Catalysis of Olefin Photoreactions. 10. Synthesis of Multicyclic Carbon Networks by Photobicyclization, Salomon, R.G.; Ghosh, S.; Zagorski, M.G.; Reitz, M. J. Org. Chem. 1982, 47, 829.
Copper(I) Catalysis of Olefin Photoreactions. 9. Photobicyclization of a-, b-, and g-Alkenylallyl Alcohols, Salomon, R.G.; Ghosh, S.; Zagorski, M.G.; Reitz, M. J. Am. Chem. Soc. 1982, 104, 998.
Diethyl Oxomalonate. An Improved Synthesis, Pardo, S.N.; Salomon, R.G. J. Org. Chem. 1981, 46, 2598.
Generation of Ester Enolates by Reductive a-Deacetoxylation, Pardo, S.N.; Ghosh, S.; Salomon, R.G. Tetrahedron Lett. 1981, 1885.
Prostaglandin Endoperoxides. 11. Mechanism of Amine Catalyzed Fragmentation of 2,3-Dioxabicyclo[2.2.1]heptane, Zagorski, M.G.; Salomon, R.G. J. Am. Chem. Soc. 1980, 102, 2501.
Synthesis of Allylcarboxylic Acids from Olefins with Diethyl Oxomalonate, an Eneophilic Equivalent and Carbon Dioxide, Salomon, M.F.; Pardo, S.N.; Salomon, R.G. J. Am. Chem. Soc. 1980, 102, 2473.
The Peroxide Transfer Reaction, Salomon, M.F.; Salomon R.G. J. Am. Chem. Soc. 1979, 101, 4290.
Extraordinary Reactivity of the Prostagladin Endoperoxide Nucleus. Nonpolar Rearrangement of 2,3-Dioxabicyclo- [2.2.1]heptane and -[2.2.2]octane, Coughlin, D.J.; Salomon, R.G. J. Am. Chem. Soc. 1979, 101, 2761.
Copper(I) Catalysis of Olefin Photoreactions. 8. A Stepwise Olefin Metathesis Synthesis of Cyclopent-2-en-1-ones via Photobicyclization of 3-Hydroxyhepta-1,6-dienes, Salomon, R.G.; Coughlin, D.J; Easler, E.M. J. Am. Chem. Soc. 1979, 101, 3961.
A New Synthetic Approach to Alkylidene Cyclohexenes. Reduction-Protodesilylation of Benzylsilanes, Coughlin, D.J.; Salomon, R.G. J. Org. Chem. 1979, 44, 3784.
The Prostaglandin Endoperoxide Nucleus and Related Bicyclic Peroxides. Synthetic and Spectroscopic Studies, Coughlin, D.J.; Brown, R.S.; Salomon, R.G. J. Am. Chem. Soc. 1979, 101, 1533.
Crystal and Molecular Structure of 1,4-Diphenyl-2,3-dioxabicyclo[2.2.1]heptane, Langs, D.A.; Erman, M.G.; DeTitta, G.T.; Coughlin, D.J.; Salomon, R.G. J. Cryst. and Mol. Struct. 1978, 8, 239.
Aleuritic Acid, an Abundant Source of Prostanoid Synthons, Reuter, J.M.; Salomon, R.G. J. Org. Chem. 1978, 43, 4247.
Rhodium Catalysis of Allylic Oxidations with Molecular Oxygen, b-Silyl-2-cycloalkenones, Reuter, J.M.; Sinha, A.; Salomon, R.G. J. Org. Chem. 1978, 43, 2438.
Copper(I) Catalysis of Olefin Photoreactions. Photocycloaddition of Allyl Alcohol, Salomon, R.G.; Sinha, A. Tetrahedron Lett. 1978, 1367.
Prostaglandin Endoperoxides. 6. A Polar Transition State in The Thermal Rearrangement of 2,3-Dioxabicyclo[2.2.1]heptane, Salomon, R.G.; Salomon, M.F.; Coughlin, D.J. J. Am. Chem. Soc. 1978, 100, 660.
Propargloxy Ketone Enol Ether-Claisen Rearrangement. Synthesis of Allenyl Ketones from Propargyl Alcohols, Reuter, J.M.; Salomon, R.G. Tetrahedron Lett. 1978, 3199.
Catalysis of Olefin Photoreactions by Transition Metal Salts, Salomon, R.G., ACS Advances in Chemistry, Series 168, 1978, 174.
Allyloxy Ketone Enol Ether-Claisen Rearrangement. Regiospecific Synthesis of Allyl Ketones from Allyl Alcohols,Tetrahedron Lett. 1977, 3235.
Ruthenium(II) Catalyzed Rearrangement of Diallyl Ethers. A Synthesis of g,d-Undsaturated Aldehydes and Ketones, Reuter, J.M.; Salomon, R.G. J. Org. Chem. 1977, 42, 3360.
2,3-Dioxabicyclo[2.2.1]heptane. The Strained Cyclic Peroxide Nucleus of Prostaglandin Endoperoxides, Salomon, M.F.; Salomon, R.G. J. Am. Chem. Soc. 1977, 99, 3501.
Peroxide Transfer from Tri-n-butyltin Peroxides. A Mild New Synthesis of Dialkyl Peroxides, Salomon, M.F.; Salomon, R.G. J. Am. Chem. Soc. 1977, 99, 3500.
Copper(I) Catalysis of Olefin Photoreactions. Photorearrangement and Photofragmentation of Methylenecyclopropanes, Salomon, R.G.; Sinha, A.; Salomon, M.F. J. Am. Chem. Soc. 1978, 100, 520.
Ruthenium(II) Catalysis in Redox Fragmentation of Allyl Ethers, Salomon, R.G.; Reuter, J.M. J. Am. Chem. Soc. 1977, 99, 4372.
Rhodium(I) Catalysis of Vinylcyclopropane Epimerization and Ring Cleavage Rearrangements, Salomon, R.G.; Salomon, M.F.; Kachinski, J.L.C. J. Am. Chem. Soc. 1977, 99, 1043.
Synthesis and Thermal Reactivity of Some 2,3-Dioxabicyclo[2.2.1]heptane Models of Prostaglandin Endoperoxides, Coughlin, D.J.; Salomon, R.G. J. Am. Chem. Soc. 1977, 99, 655.
A Synthesis of Mixed Dialkylperoxideds via Reaction of an Alkylhydroperoxide with Alkyl Trifluoromethane Sulfonates, Salomon, M.F.; Salomon, R.G.; Gleim, R.D. J. Org. Chem. 1976, 41, 3983.
Copper(I) Catalysis of Olefin Photoreactions. Photorearranement and Photo-fragmentation of 7-Methylenenorcarane, Salomon, R.G., Salomon, M.F. J. Am. Chem. Soc. 1977, 99, 655.
Carbonyl-Alkyne Exchange of 2H-Pyrans. A New Aryl Annelation Method, Salomon, R.G.; Burns, J.R.; Dominic, W.J. J. Org. Chem., 1976, 41, 2918.
Zero Bridge Cleavage and a Neighboring Hydroxyl Group Effect in the Oxymercuration of Bicyclo[3.1.0]hexanes, Salomon, R.G.; Gleim, R.D. J. Org. Chem. 1976, 41, 1529.
Regioselectivity and the Role of Olefin Coordination in Rhodium(I) Catalyzed Rearrangement of Vinylcyclopropanes, Salomon, M.F.; Salomon, R.G. Chem. Commun. 1976, 89.
Rhodium(I) Catalysis in Olefin Photoreactions, Salomon, R.G.; Sanadi, N.E. J. Am. Chem. Soc. 1975, 97, 6214.
b-Alkylalkanedioic Acids from Cycloalkenones via Michael Alkylation-Methoxycarbonylation, Salomon, R.G.; Salomon, M.F. J. Org. Chem. 1975, 40, 1488.
Vinylcyclopropanation of Olefins with Vinyldiazomethane, Salomon, R.G.; Salomon, M.F.; Heyne, T.R. J. Org. Chem. 1975, 40, 756.
A Facile One-Step Synthesis of 5-Silaspiro[4.4]nona-2,7-diene, Salomon, R.G. J. Org. Chem. 1974, 39, 3463.
Stereospecific Total Synthesis ofProstaglandins via Reaction of a-Alkylcyclopentenones with Organocuprates, Sih, C.J.; Salomon, R.G.; Price, P.; Sood, R.; Peruzzotti, G. J. Am. Chem. Soc. 1975, 97, 857.
Acetone Sensitized Photoepimerization about Unactivated Tertiary Carbon Atoms, Salomon, R.G.; Salomon, J.K.; Kochi, J.K.Tetrahedron Lett., 1973, 4387.
Copper(I) Catalysis in Photo-Cycloadditions. II. Cyclopentene, Cyclohexene, and Cycloheptene, Salomon, R.G.; Floting, K.; Streib, W.E.; Kochi, J.K. J. Am. Chem. Soc. 1973, 1145.
Copper(I) Catalysis in Photo-Cycloadditions. I. Norbornene, Salomon, R.G.; Kochi, J.K. J. Am. Chem. Soc. 1973, 1137.
Carbon-13 NMR Spectra of Olefin-Copper(I) Complexes, Salomon, R.G.; Kochi, J.K. J. Organometal. Chem. 1973, 64, 135.
Stereochemistry of the Exhaustive Methylation of Alcohols with Trimethylaluminum, Salomon, R.G.; Kochi, J.K. J. Org. Chem. 1973, 38, 3715.
Copper(I) Triflate: A Superior Catalyst for Olefin Photodimerization, Salomon, R.G.; Kochi, J.K. Tetrahedron Lett. 1973, 2529.
Copper(I) Catalysis in Cyclopropanations with Diazo Compounds. The Role of Olefin Coordination, Salomon, R.G.; Kochi, J.K. J. Am. Chem. Soc. 1973, 95, 3300.
Cationic Olefin Complexes of Copper(I). Structure and Bonding in Group 1b Metal-Olefin Complexes, Salomon, R.G.; Kochi, J.K. J. Am. Chem. Soc. 1973, 95, 1889.
Structure and Bonding in Cationic Olefin Complexes of Copper(I) by NMR, Salomon, R.G.; Kochi, J.K. J. Organometal. Chem. 1972, C7.
Cuprous Triflate: Cationic Benzene and Olefin Complexes of Copper(I), Salomon, R.G.; Kochi, J.K. Chem. Commun. 1972, 559.
Total Synthesis ofProstaglandins. III. 11-Desoxyprostaglandins, Sih, C.J.; Salomon, R.G.; Price, P.; Sood, R.; Peruzzotti, G. Tetrahedron Lett. 1972, 2435.
Total Synthesis ofProstaglandins. II. Prostaglandin E1, Sih, C.J.; Price, P.; Sood, R.; Salomon, R.G.; Peruzzotti, G.; Casey, M. J. Am. Chem. Soc. 1972, 94, 3643.
Total Synthesis of (±)-15-Deoxyprostaglandin E1, Sih, C.J.; Salomon, R.G.; Price, P., Peruzzotti, G.; Sood, R. Chem. Commun. 1972, 204
Thermal Sigmatropic Migration of the Carbomethoxyl Group, Berson, J.A.; Salomon, R.G. J. Am. Chem. Soc. 1971, 93, 4620.
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Salomon, R. G., Wang, Hua "Pathological and physiological activities of carboxyalkylpyrrole (CAP) protein modifications derived from oxidized phospholipids" , 2013, Bioactive Lipids in Cancer, Inflammation, and Related Diseases, 13th International Conference" San Juan, Puerto Rico, November 3 – 6.
F. Cruz-Guilloty, A. Saeed, S. Duffort, Y. Tan, A. Ballmick, R. G. Salomon, V. L. Perez "Carboxyethylpyrrole-specific T cells Promote M1 Macrophage Polarization: Innate and Adaptive Immunity Cooperate in the Early Onset of Age-Related Macular Degeneration" 2012 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 6-10.
A. M. Saeed., F. Cruz-Guilloty, S. J. Duffort, R. G. Salomon, V. L. Perez "Polarization Of Macrophages Toward M1 Pro-inflammatory Phenotype By Oxidative Stress-induced Modifications Associated With Age-related Macular Degeneration" 2012 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 6-10.
G-F Jang, L. Zhang, L. Hong, H. Wang, R. G. Salomon, J. W. Crabb "Quantification Of CEP By LC MS/MS" 2012 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 6-10.
Salomon, R.G., Hong, L., Hollyfield, J.G. "The discovery of carboxyethylpyrroles (CEPs): critical insignts into AMD, autism, cancer, and wound healing frombasic research on the chemistry of oxidized phospholipids" , 2011, Bioactive Lipids in Cancer, Inflammation, and Related Diseases, 12th International Conference" Seattle, Washington, September 18-21.
F.C. Guilloty, J.J. Echegaray, S. Duffort1,2, M. Betancourt, E. Viteri, Y. Tan, A. Ballmick, R. Salomon, V.L. Perez "Quantitative Infiltration of Pro-Inflammatory M1 Macrophages Into the Outer Retina Marks the Early Onset of Immune-Mediated Age-Related Macular Degeneration" 2011 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 1-5.
C.D. Charvet, G.Y. Heo, J. Laird, R.G. Salomon, I.V. Turko, I.A. Pikuleva "Post-translational Modification Of CYP27A1 By Oxidative Derivatives Of Arachidonic Acid, Isolevuglandins, Occurs In Human Retina" 2011 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 1-5.
S.S. Huang, W. Zou, L. Hong, R. Salomon, J. Liu "Identification of Autoreactive T Cells in Age-Related Macular Degeneration Patients" 2010 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
J.G. Hollyfield, M.E. Rayborn, M. Yu, K.G. Shadrach, X. Yang, B.A. Bell, N.S. Peachey, R.G. Salomon "Sustained RPE Pathology During Aging of Mice Immunized With CEP-MSA" 2010 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
F. Cruz Guilloty, J.J. Echegaray, Y. Tan, E.J. Ewald, R.G. Salomon, V.L. Perez "Autoreactive T Cells, but Not B Cells, Lead the Adaptive Immune Response Against Oxidative Stress-Mediated Modifications of Self Antigens in a Mouse Model of Age-Related Macular Degeneration" 2010 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
B. Aredo, A. McMahon, P.W. Chen, J.Y. Niederkorn, L. Hong, R.G. Salomon, W. Kedzierski, R. Ufret-Vincenty "AMD-Like Changes in Cfh Transgenic Mice: Can Antigen-Specific Immunity Enhance the Phenotype?" 2010 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
Huang, S.S., Zou, W., Hong, L., Salomon, R.,Liu, J., Identification of Autoreactive T Cells in Age-Related Macular Degeneration Patients, 2010, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
Hollyfield, J.G., Rayborn, M.E., Yu, M., Shadrach, K.G., Yang, X., Bell, B.A., Peachey, N.S., Salomon, R.G., Sustained RPE Pathology During Aging of Mice Immunized With CEP-MSA, 2010, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
Aredo, B., McMahon, A., Chen, P.W., Niederkorn, J.Y., Hong, L., Salomon, R.G., Kedzierski, W., Ufret-Vincenty, R., AMD-Like Changes in Cfh Transgenic Mice: Can Antigen-Specific Immunity Enhance the Phenotype?, 2010, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
Cruz Guilloty, F., Echegaray, J.J., Tan, Y., Ewald, E.J., Salomon, R.G., Perez, V.L. , Autoreactive T Cells, but Not B Cells, Lead the Adaptive Immune Response Against Oxidative Stress-Mediated Modifications of Self Antigens in a Mouse Model of Age-Related Macular Degeneration, 2010, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 2-6.
Li, Wei, Zhou, Rong, Laird, James M., Roychowdhury, Sanjoy, Nagy, Laura E., Crabb, John W., Lu, Liang, Walsh, William J., Fakhoury, Evelyn, and Salomon, R. G., Isolevuglandins covalently modify ethanolamine phospholipids: LC-MS/MS detection and quantitative analysis of hydroxylactam adducts as an index of chronic inflammation, 2009, Bioactive Lipids in Cancer, Inflammation, and Related Diseases, 11th International Conference" Cancun, Mexico, October 25 – 28.
K. Renganathan, J. Gu, R. Collier, C. Romano, R.G. Salomon, M. Rayborn, J.G. Hollyfield, J.W. Crabb, Drugs That Prevent Retinal Light Damage Impact CEP Biomarker Levels, 2009, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 3-7.
S.A. Hagstrom, J. Gu, G.J.T. Pauer, X. Yue, U. Narendra, G.M. Sturgill, N.S. Peachey, R.G. Salomon, J.W. Crabb, Predicting Susceptibility to Age-Related Macular Degeneration With Genomic and Proteomic Biomarkers, 2009, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 3-7.
A.K. Junk, B. Govindarajan, M. Algeciras, R.G. Salomon, B. Anand-Apte, S.K. Bhattacharya, Increased Isolevuglandin Modified Proteins in Glaucomatous Astrocytes, 2009, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 3-7
L.A. Kuttner-Kondo, L. Hong, R.G. Salomon, J.G. Hollyfield, Antibody Mapping of Complement C3 Binding to CEP-BSA, 2009, Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida, May 3-7.
Smith, M.A., Siedlak, S.L., Evans, T.A., Salomon, R.G., Perry, G., Zhu, X., Oxidative Damage in the Autistic Brain: Therapeutic Considerations, 2009, 4th International Conference on Oxidative/Nitrosative Stress and Disease, New York City, October 28-30.
Xiaodong Gu; Wujuan Zhang; Jaewoo Choi; Wei Li; Xi Chen; James Laird; Robert G. Salomon, Singlet oxygen cycloadducts of hydroperoxy dienes fragment to γ-hydroxy alkenals; a reaction that is promoted by vitamin E, 2009,57th ASMS Conference on Mass Spectrometry & Allied Topics, Philadelphia, PA, May 31 - June 4.
Jaewoo Choi; Wujuan Zhang; Xiaodong Gu; Xi Chen; Li Hong; James M. Laird; Robert G. Salomon, A Nonenzymatic route to lysophosphatidylcholine: spontaneous deacylation of oxidatively damaged phospholipids, 2009, 57th ASMS Conference on Mass Spectrometry & Allied Topics, Philadelphia, PA, May 31 - June 4.
W. Li, J.M. Laird, L. Lu, S. Roychowdhury, L.E. Nagy, and R.G. Salomon, LC-MS/MS Detection of Isolevuglandin-ethanolamine Phospholipid Adducts In Vivo, 2009 American Society for Mass Spectrometry Sanibel Conference, Florida January 23-26.
X. Yang, Y. Li, M.E. Rayborn, K.G. Shadrach, V. Bonilha, V. Perez, R.G. Salomon, J.G. Hollyfield, Identification of Inflammatory Cells Migrating in the Interphotoreceptor Matrix Following Acute Immunization of Mice With CEP-MSA, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
J. Gu, U. Narendra, G. Pauer, P. Nerone, S. Bamba, X. Yue, R.G. Salomon, S.A. Hagstrom, J.W. Crabb, Plasma Carboxyethylpyrrole and AMD Risk Genotypes, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
T. Yamamoto, R. Venkatesh, X. Yang, Y. Li, M.E. Rayborn, K.G. Shadrach, V. Perez, R.G. Salomon, J.G. Hollyfield, Time Course for CEP Antibody Development and C3d Deposition in Bruch's Membrane Following Immunization With CEP-MSA, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
K. Sayanagi, Y. Li, M.E. Rayborn, K.G. Shadrach, X. Yang, V. Perez, R.G. Salomon, J.G. Hollyfield, Electron Microscopic Analysis of Drusen Deposits That Develop Following Immunization With CEP-MSA, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
J.G. Hollyfield, V.L. Bonilha, M.E. Rayborn, X. Yang, K.G. Shadrach, L. Lu, R.L. Ufret, R.G. Salomon, V. Perez, Age-related Macular Degeneration: the Molecular Link Between Oxidation and Inflammation, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
B. Govindarajan1, R.G. Salomon2, S.K. Bhattacharya3, B. Anand-Apte, Role of Oxidatively Modified Extracellular Matrix Proteins and Matrix Metalloproteinases in Glaucomatous Trabecular Meshwork Plasma, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
X. Zhan, J. Gu1, X. Gu, J.S. Crabb, P. Nerone, S. Bamba, X. Yue, R.G. Salomon, J.W. Crabb, Identification of Carboxyethylpyrrole-Modified Proteins in AMD Plasma, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
W.-H. Lee, A. Junk, B. Govindarajan, J. Laird, R.G. Salomon, S.K. Bhattacharya, Calpain-1 Processing Differences in Normal and Diseased Ocular Tissues, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
J.G. Hollyfield, M.E. Rayborn, K.G. Shadrach, X. Yang, Y. Li, R.G. Salomon, V. Perez., Correlation Between RPE Pathology and CEP Antibody Titer in Mice Immunized With CEP-MSA, 2008 Association for Research in Vision and Opthalmology Meeting, Fort Lauderdale, Florida April 27- May 1.
R.G. Salomon, X. Chen, W. Zhang, Oxidatively truncated phospholipids: generation, protein adduction, and biological activities of g-hydroxyalkenal phospholipids, 10th International Conference on Bioactive Lipids in Cancer, Inflammation, and Related Diseases, Montreal, Canada, September 16-19, 2007
X. Zhu, T. A. Evans, S. L. Siedlak, L. Lu, W. Mcginnis, R. J. Castellani, R. G. Salomon, M. A. Smith, G. Perry, The autistic phenotype exhibits a remarkably localized modification of brain protein by products of free radical-induced lipid oxidation, 2007 Society for Neuroscience Meeting, San Diego, California, November 6.
Kutralanathan Renganathan, Kwok-Peng Ng, Matthew W. Davies, Xiaorong Gu, John S Crabb, Malgorzata B. Rózanowska, Mary E. Rayborn, Yong Li, Robert G. Salomon, Janet R. Sparrow, Joe G. Hollyfield, Michael E. Boulton, John W. Crabb, Does Lipofuscin Contain Protein? Amino Acid, Protein, and Ultrastructural Analysis of Human Lipofuscin, 2007 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida April 29-May 4.
J Gu, X Zhan, JS Crabb, E Bala, K Renganathan, X Gu, SA Hagstrom, H Lewis, RG Salomon, JW Crabb, Oxidative Modifications As Biomarkers For AMD, 2007 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida April 29-May 4.
Hollyfield JG, Rayborn ME, Yang X, Ufret R, Liang Y, Yu M, Shadrach KG, Peachey NS, Salomon RG and Perez VL, Identification of an Inflammatory Signal from the Outer Retina Causing Age-Related Macular Degeneration, 2007 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida April 29-May 4.
B. Govindarajan, S. Bhattacharya, J. Crabb, B. Anand-Apte, R. G. Salomon, Lipid-Derived Oxidative Protein Modification and Eye Diseases: Age-Related Macular Degeneration and Glaucoma, 2006 (97th) AOCS Annual Meeting & Expo, Saint Louis, Missouri, April 30 - May 03.
Zhang, Wujuan; Chen, Xi; Sun, Mingjiang; Salomon, Robert G., "Vitamin E promoted fragmentation of lipid dihydroperoxides" 230th ACS National Meeting, Washington, D.C., United States, Aug.28-Sept. 1, 2005.
J. Gu, J.S. Crabb, E. Bala, K. Renganathan, X. Gu, S.A. Hagstrom, H. Lewis, R.G. Salomon, J.W. Crabb, "Peptidomic Profiling of Plasma for AMD Biomarkers" 2006 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida April 29-May 4.
Robert G. Salomon, Exploring the Pathological Consequences of Lipid Oxidation: A Chemistry Perspective, Friday, February 18, 2005, Department of Chemistry and Biochemistry, University of South Carolina, Charlotte, South Carolina.
B.G. Gugiu, M.Rozanowska, B.Rozanowski, M.E. Rayborn, V.L. Bonilha, X.Gu, R.G. Salomon, J.G. Hollyfield, M.E. Boulton, J.W. Crabb Proteomic and Ultrastructural Analyses of Human Lipofuscin, 2005 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida (Monday, May 2 11:15 AM - 1:00 PM).
J.Gu, Z.Wu, J.S. Crabb, X.Gu, S.A. Hagstrom, J.E. Sears, H.Lewis, R.G. Salomon, J.W. Crabb Plasma Peptidomics for Predicting AMD Susceptibility, 2005 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida (Tuesday, May 3 3:00 PM - 4:45 PM).
K.Renganathan, J.Gu, B.Gugiu, X.Gu1, R.Darrow, H.Lewis, R.G. Salomon, D.T. Organisciak, J.W. Crabb Similarities in Plasma Oxidative Modifications From Retinal Light Damage and AMD, 2005 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida (Tuesday, May 3 3:00 PM - 4:45 PM).
S.P. Annangudi, E.J. Rockwood, S.D. Smith, R.G. Salomon, S.K. Bhattacharya, J.W. Crabb Oxidative Protein Modifications in Glaucomatous Trabecular Meshwork, 2005 Association for Research in Vision and Ophthalmology Meeting, Fort Lauderdale, Florida (Wednesday, May 4 8:30 AM - 10:15 AM).
Robert G. Salomon, Amazing Antibodies: Exquisitely Specific Tools for Analysis of Lipid-Derived Protein Modifications, Thursday morning, June 2, 2005, Sichuan University, Chengdu, China.
Robert G. Salomon, Lipid Oxidation and Atherosclerosis: A Chemistry Perspective, Thurdsay afternoon, June 2, 2005, Sichuan University, Chengdu, China.
Robert G. Salomon, Exploring Lipid Oxidation Mechanisms: A Tool for Discovering Biologically Important Chemistry, Friday, June 3, 2005, Sichuan University, Chengdu, China.
Zhang, Wujuan; Chen, Xi; Sun, MIngjiang; Salomon, Robert G.. Vitamin E promoted fragmentation of lipid dihydroperoxides. 230th ACS National Meeting, Washington, DC, United States, Aug. 28-Sept. 1, 2005.
Salomon, R.G. (2004) Isolevuglandins, oxidatively truncated phospholipids and atherosclerosis. Keynote Lecture at the 8th International Symposium on the Maillard Reaction, Monday, August 30,2004 in Charleston, South Carolina.
Gugiu, B. G., Sun, M. and Salomon, R. G. (2003) Generation, total syntheses, and identification of biologically active oxidized ethanolamine phospholipids. Abstracts of Papers, 226th ACS National Meeting, New York, NY, United States, September 7-11,2003 ORGN-552.
Mesaros, A. C., Sun, M. and Salomon, R. G. (2003) Mechanistic insights into the oxidative fragmentation of linoleic acid. Abstracts of Papers, 226th ACS National Meeting, New York, NY, United States, September 7-11, 2003 ORGN-546.
Sun, M. and Salomon, R. G. (2003) New pathways that generate oxidatively truncated lipids. Abstracts of Papers, 225th ACS National Meeting, New Orleans, LA, United States, March 23-27,2003 ORGN-637.
Crabb JW, Yan L, Miyagi M, Gu X, West KA, Kamei M, Sakaguchi H, Shadrach K, Rayborn ME, Marmorstein A, RG Salomon, and JG Hollyfield. (2002) Proteomic Approaches to Age-Related Macular Degeneration. Annual Meeting of the Association for Research in Vision and Ophthalmology, May 6-10, 2002, Ft. Lauderdale, FL.
Crabb JW, L Yan, M Miyagi, X Gu, KA West, A Marmorstein, M Kamei, ME Rayborn, RG Salomon, and JG Hollyfield (2002) Proteomics, Oxidative Damage and Age-Related Macular Degeneration. American Society for Biochemistry and Molecular Biology Satellite Meeting, Scientific and Technical Challenges in the Human Proteome, New Orleans LA, April 19-20, 2002
Oxidation of Docosahexaenoate Phospholipids: An Electrospray Mass Spectroscopic Study. Gu X, M Miyagi, M Sun, B Gugiu, JW Crabb, and RG Salomon (2001) Annual Meeting of the American Chemical Society, August 26-30, 2001, Chicago, IL.
Protein Modification from Oxidation of Docosahexanoate Phospholipids. Gu X, M Miyagi, ME Ray born, JG Hollyfield, RG Salomon and JW Crabb (2001) Proceedings of the 49th ASMS Conference on Mass Spectrometry and Allied Topics, Chicago, IL, May 27-31,2001.
Proteomic approaches to the study of retinal degenerative diseases. Crabb JW, L Yan, KA West, M Miyagi, JS Crabb, A Marmorstein, X Gu, M Kamei, ME Rayborn, JG Hollyfield, and RG Salomon (2000) IXth International Symposium on Retinal Degeneration, Oct 9-14, 2000, Durango CO
Oxidative Protein modification in AMD from Docosahexaenoic Acid. Crabb, JW, X Gu, L Yan, DE Rohde, KA West, M Kamei, ME Rayborn, JG Hollyfield, and RG Salomon (2000) Annual Meeting of the Association for Research in Vision and Ophthalmology, April 30-May 5, 2000, Ft. Lauderdale, FL. Invest. Ophthal. Vis Sci 41: 2109, S399
Oxidized phospholipids that are ligands for the scavenger receptor CD36 induce platelet activation in CD36 dependent manner. E.A.Podrez, T.V. Byzova, E. Batyreva, Z. Shen, Y Deng, M. Febbraio, R.G. Salomon, H.F. Hoff, and S.L.Hazen. Cleveland Clinic Foundation, Case Western Reserve University, Cornell University, USA. Second Annual conference on Arteriosclerosis, Thrombosis, and Vascular Biology. (American Heart Association) May 11-13. 2001 Arlington,VA
A novel class of specific oxidized choline lycerophospholipids serve as ligands for the macrophage scavenger receptor CD36. E.A.Podrez, E. Batyreva, Z. Shen, Y Deng, R.G. Salomon, H.F. Hoff, and S.L.Hazen. Free Radical Biology and Medicine, 2000, 29, Suppl., S109
L.M. Sayre, G. Xu, R. G. Salomon, M. A. Smith, and G. Perry, "Mechanisms of Oxidative Stress Protein Damage in Neurodegenerative Disease", 216th National ACS Meeting, Boston, Massachussetts, 8/27/98, Division of Chemical Toxicology.
L. M. Sayre, M. A. Smith, R. G. Salomon, L. I. Sweda and G. Perry, "Advanced lipoperoxidation end products (ALEs) in Alzheimer disease", 6th International Conference on Alzheimer's Disease and Related Disorders, Amsterdam, 7/23/98.
K. Kaur, R. G. Salomon, "The Effects of Taurine on Oxidative Modification of Low Density Lipoprotein", 30th Central Regional ACS Meeting, Clevland, OH, 5/29/98, Division of Organic Chemistry, paper 200.
Y. Deng,R. G. Salomon, "Synthesis of g-Hydroxy-a,b-Unsaturated Core Aldehydes", 30th Central Regional ACS Meeting, Clevland, OH, 5/29/98, Division of Organic Chemistry, paper 199.
K. Kaur, R. G. Salomon, "2-(w-Carboxyalkyl)pyrroles: Immunodetection in Oxidized Loe Density Lipoproteins and Human Plasma", 214th National ACS Meeting, Las Vegas, Nevada, 9/10/97, Division of Chemical Toxicology, paper 34.
R. G. Salomon, G. Subbanagounder, "Total Synthesis of iso[4]-Levuglandin E2", 211th National ACS Meeting, New Orleans, Louisiana, 3/22/96, paper 321.
R. G. Salomon, G. Subbanagounder, U. Singh, J. O'Neil, H. Hoff, "Levuglandin-protein Adducts in Human Plasma and in Oxidized Low Density Lipoproteins" International Chemical Congress of Pacific Basin Societies (PacifiChem) Symposium on Arachidonic Acid Metabolism in Health and Disease, Honolulu, Hawaii, 12/21/95, paper 573
G .Subbanagounder, R. G. Salomon, "An Immunoassay for Levuglandin Derived Pyrroles", Central Regional ACS Meeting, Akron, Ohio, 6/1/95.
R. G. Salomon, S. Ghosh, "Homogeneous Metal-Catalyzed Photochemistry in Organic Synthesis", 4th Chemical Congress of North America and 202nd ACS national meeting, New York City, 8/29/91, paper 339.
R. G. Salomon, B. Basu, S. Roy, R. B. Sharma, "Total Synthesis of a Marine Antitumor Agent: Spatol", 1989 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, 12/21/89, paper 729.
R. G. Salomon, "Total Synthesis of Marine Antitumor Agents", 21st Central Regional ACS Meeting, Cleveland, Ohio, 6/2/89, paper 288.
D. Foreman, R. G. Salomon, D. B. Miller, B. S. Levison, "Levuglandins Inhibit the Uterotonic Activity of SpecificProstaglandins", 69th Annual Meeting of the Endocrine Society, Indianapolis, Indiana, 6/17/87, abstract 940.
S. Ghosh, K. Lal, R. G. Salomon, "Hydroxyl-directed Regioselective Monodemethylation of Poly-methoxy Arenes", 18th Central Regional ACS Meeting, Bowling Green, Ohio 6/3/86, paper 338.
R. G. Salomon, "Stereocontrol in the Total Synthesis of Natural Products", 18th Central Regional ACS Meeting, Bowling Green, Ohio, 6/3/86, paper 282.
K. Lal, S. M. Mazza, R. G. Salomon, "Total Synthesis and a New Proposal for the Structure of Robustadials", 191st ACS National Meeting, New York City, N. Y., 4/17/86, paper.
R. G. Salomon, K. Avasthi, "Synthesis of Methylenecyclobutanes and Cyclopentanones via Copper(I)-Catalyzed Photoreactions of b-Silyl Diallyl Ethers", 17th Central ACS Regional Meeting, Akron, Ohio, 6/5/85, paper 163.
K. Avasthi, R. G. Salomon, "A Copper(I)-Catalyzed Photobicyclization Route for Synthesis of 7-Substituted Norbornanes", 17th Central Regional ACS Meeting, Akron, Ohio, 6/5/85, paper 162.
M. F. Salomon, S. Ghosh, E. M. Easler, T. N. Illiadis, R. G. Salomon, "Oxidative Bisdecarboxylation of Alkoxymalonic Acids with Cerium(IV)", 17th Central Regional ACS Meeting, Akron, Ohio, 6/5/85, paper 161.
R. S. Bhide, R. G. Salomon, "Total Synthesis of K-76", 17th Central Regional ACS Meeting, Akron, Ohio, 6/5/85, paper 166.
*R. G. Salomon, D. B. Miller, M. G. Zagorski, B. S. Levison, K. Lal, S. R. Raychaudhuri, K. Avasthi, "Levuglandins: Isolation, Characterization, and Total Synthesis of New Secoprostanoid Products from Prostaglandin Endoperoxides", Kyoto Conference onProstaglandins, Japan, 11/26/84, paper S4-17.
R. G. Salomon, D. B. Miller, S. R. Raychaudhuri, K. Avasthi, "Asymmetric Total Synthesis of Levuglandin E2 (LGE2)", 188th ACS National Meeting, Philadelphia, 8/30/84, paper 0-206.
D. B. Miller, K. Lal, R. G. Salomon, "Levuglandins, New Seco Prostanoic Acid Products from the Prostaglandin Endoperoxide PGH2", 188th ACS National Meeting, Philadelphia, 8/30/84, paper 0-205.
N. D. Sachinvala, R. G. Salomon, "Total Synthesis of Spatane Diterpenes", 188th ACS National Meeting, Philadelphia, 8/27/84, paper 0-48.
*R. G. Salomon, "Synthetically Interesting New Photochemistry", 3rd ACS Joint Great Lakes and Central Regional Meeting, Kalamazoo, MI., 5/24/84, paper 303.
*R. G. Salomon, "The Copper Key to a Treasure of New Organic Photochemistry", ACS Joint Central and Great Lakes Regional Meeting, Dayton, Ohio, 5/20/81, paper 163.
*R. G. Salomon and D. B. Miller, "Levuglandins: New Natural Products Derived from Prostaglandin Endoperoxides", 33rd ACS Southeastern Regional Meeting, Lexington, Kentucky, 11/81, paper 240.
S. Pardo, R. G. Salomon, "Synthesis of Diethyl Allylmalonates from Olefins", 179th ACS National Meeting, Houston, 3/80, paper 0-92.
M. G. Zagorski, R. G. Salomon, "Mechanism of Amine Catalyzed Fragmentation of 2,3-Dioxabicyclo[2.2.1]heptane, the Prostaglandin Endoperoxide Nucleus", 179th ACS National Meeting, Houston, 3/80, paper 0-59.
R. G. Salomon, M. F. Salomon, M. G. Zagorski, J. M. Reuter, D. J. Coughlin, "Total Synthesis Refutes the Postulated Structure of Leucogeneol", 179th ACS National Meeting, Houston, 3/80, paper 0-59.
M. F. Salomon, R. G. Salomon, "Synthesis of Allylcarboxylic Acids from Olefins with Diethyl Oxomalonate, an Eneophilic Equivalent of Carbon Dioxide", 178th ACS National Meeting, Washington, D.C., 9/79, paper 0-63.
R. G. Salomon, D. J. Coughlin, "Synthesis of Cyclopent-2-ene-1-ones from 3-hydroxyhepta-1,6-dienes by a Stepwise Olefin Metathesis. Copper(I) Catalysis of Olefin Photoreactions", 177th ACS National Meeting, Honolulu, 4/79, paper 0-215.
D. J. Coughlin, M. F. Salomon, R. G. Salomon, "Remarkably Large Negative Activation Entropy for Nonpolar Rearrangement of 2,3-Dioxabicyclo[2.2.1]heptane. The Prostaglandin Endoperoxide Nucleus", 177th ACS National Meeting, Honolulu, 4/79, paper 0-70.
R. G. Salomon, M. F. Salomon, D. J. Coughlin, "Endoperoxides Chemistry. Thermal Rearrangement of 2.3-Dioxabicyclo[2.2.1]heptane", 174th ACS National Meeting, Chicago, 8/77, paper 0-180.
J. L. C. Kachinski, R. G. Salomon, "Regiospecific Synthesis of Allyl Ketones from Allyl Alcohols via Claisen Rearrangement of Allyloxy Ketone Enol Ethers", 174th ACS National Meeting, Chicago, 7/77, paper 0-171.
R. G. Salomon, "Catalysis of Olefin Photoreactions by Transition Metal Salts", 174th ACS National Meeting, Chicago, 8/77, paper I-118.
D. J. Coughlin, R. G. Salomon, "Endoperoxide Chemistry. Synthesis and Thermal Reactivity of 1,4-Diphenyl-2,3-dioxabicyclo[2.2.1]heptanes", 173rd ACS National Meeting, New Orleans, 3/77, paper 0-149.
M. F. Salomon, R. G. Salomon, "Endoperoxide Chemistry. A Novel Synthesis of Dialkylperoxides via Peroxide Transfer from Tri-n-butyltin Peroxides", 173rd ACS National Meeting, New Orleans, 3/77, paper 0-148.
R. G. Salomon, M. F. Salomon, "Copper(I) Catalysis of Olefin Photoreactions. Photofragmentation and Photoarrangment of 7-Methylene Bicyclo[4.1.0] heptane", 172nd ACS National Meeting, San Francisco, 8/76, paper 0-180.
M. F. Salomon, J. L. Kachinski, R. G. Salomon, "Rhodium(I) Catalysis of Vinylcyclopropane Rearrangement; A Mechanistic Study", 170th ACS National Meeting, Chicago, 8/75, paper 0-33.
R. G. Salomon, N. El Sanadi, "Rhodium(I) Catalyzed Photorearrangement of Olefins; A Mechanistic Study", 169th ACS National Meeting, Philadelphia, 4/75, paper 0-105.
US Patent Application: 20160242397: Mouse model of retinal degeneration. Perez, Victor L., Hollyfield, Joe G., Salomon, Robert G.
US Patent Application: 20160215067: Anti-CEP antibody or fragment thereof. Salomon, Robert G., Crabb, John W., Cui, Yalun, Tomko, Nicholas D.
US 8822172: Method of Detecting Isolevuglandin Ethanolamne-Phospolipid Adducts. Salomon, Robert G. and Li, Wei
US Patent Application 20090155243: Non-human model of autoimmune disease. Perez, Victor L., Hollyfield, Joe G., Salomon, Robert G.
US Patent Application 20100143380: Compositions and methods for macular degeneration. Crabb, John W., Salomon, Robert G., Anand-apte, Bela, Ebrahem, Quteb, Renganathan, Kutralanathan
US8137991:Methods of reducing angiogenesis of age-related macular degeneration (AMD) or choroidal neovascularization by an anti-carboxyethylpyrrole (CEP) antibody. Crabb; John W., Salomon; Robert G., Anand-Apte; Bela, Ebrahem, Quteba, Reganathan, Kutralanathan.
US7172874: Diagnostic methods for age related macular degeneration (2007). Hollyfield, Joe G., Salomon, Robert G., Crabb, John W., Gu, Xiaorong
US5686250: Antibodies to LGE2 -protein antigens (1997). Salomon, Robert G.
Home Research Publications Personnel Salomon CV Publicity Funding


text:
Delaware Supreme Court Confirms Chancery Court's Broad Authority to Impose Use Restrictions on Information Obtained From Section 220 Books and Records Inspections
By John Landry & John Stigi on January 5, 2015
Posted in Corporate Governance, Courts and ADR
In United Technologies Corp. v. Treppel, No. 127, 2014, 2014 Del. LEXIS (Del. Dec. 23, 2014), the Delaware Supreme Court held that the Delaware Court of Chancery is authorized regulate how stockholders use information obtained through books and records inspections under Section 220 of the Delaware General Corporation Law ("Section 220"). The defendant corporation, in opposing a stockholder's Section 220 proceeding, had sought to bar the stockholder from using any obtained information in any legal action brought outside of Delaware. The Vice Chancellor, however, expressed the belief that the Chancery Court lacked the statutory authority to impose such a restriction. The Delaware Supreme Court reversed and identified the factors the Chancery Court should consider in exercising its discretion to impose the restriction on remand. United Technologies reaffirms the Chancery Court's important role in regulating books and records inspections in a manner that avoids inflicting unnecessary costs and burdens on corporations and their stockholders.
Following United Technologies' settlement of a United States Department of Justice investigation, a stockholder, Lawrence Treppel, sent a letter demanding that United Technologies commence litigation against certain officers and directors. At about the same time, another stockholder made a Section 220 inspection demand relating to the same investigation, which demand United Technologies' board approved. That inspection led to a derivative action in the Delaware Court of Chancery, which was eventually dismissed based on plaintiff's failure to first make a litigation demand or to show demand was excused. While this derivative suit was pending, United Technologies' board considered Treppel's litigation demand letter and rejected it. Treppel then made a Section 220 inspection demand, purportedly to enable him to evaluate the board's decision rejecting his litigation demand. United Technologies, as a condition to allowing the inspection, sought to negotiate terms by which Treppel would agree to commence any litigation arising out of the inspection in Delaware. Treppel refused and filed a Section 220 action in the Court of Chancery.
At trial, the record confirmed that Treppel had a history of filing derivative suits outside the corporation's state of incorporation. United Technologies requested the Chancery Court restrict Treppel from using any obtained information in any litigation outside Delaware. The Chancery Court allowed the inspection, but ruled that it lacked authority to impose the restriction. Instead, it identified a charter or by-law provision as the proper mechanism for a Delaware corporation to protect its interest in litigating in Delaware. After Treppel filed his Section 220 action, United Technologies had in fact adopted such a provision — designating Delaware as the exclusive forum for any derivative or stockholder litigation. Treppel, however, insisted this provision would not apply to any subsequent derivative action by him because the provision post-dated his purchase of shares in United Technologies.
The Delaware Supreme Court reversed the Chancery Court's decision that it lacked authority to impose the requested use restriction, noting that Section 220(c) authorizes the Chancery Court in the exercise of discretion to prescribe "any limitations or conditions . . . as the Court may deem just and proper." The statute imposes no limits on the Chancery Court's authority to restrict the use of information gained from an inspection when the corporation's legitimate interests are threatened. Hence, the Supreme Court found the Chancery Court had erred, and remanded the case to the Chancery Court.
In remanding, the Supreme Court identified, "case-specific" factors for the Chancery Court's consideration bearing on "the legitimate concern on United Technologies' part that it and its stockholders could face excessive costs and the risk of inconsistent rulings if Treppel were to file suit elsewhere." These factors included Treppel's investigation of the same corporate conduct that derivative litigation had already addressed, United Technologies' interest in avoiding inconsistent rulings and having Delaware law issues decided by Delaware courts, and Treppel's inability to explain why he needed to file in a non-Delaware forum. The Supreme Court also noted the importance of ensuring Section 220 actions "do not get bogged down in collateral issues," such as Treppel's argument that United Technologies' new forum selection by-law would not apply to future suits by him. The Supreme Court deemed that argument meritless on its face.
United Technologies recognizes the Chancery Court's broad authority to impose use restrictions on information acquired from books and records inspections. It also reflects the Delaware Supreme Court's concern that stockholders may misuse books and records inspections in a manner that will impose undue burdens on Delaware corporations and their stockholders.
John Landry
John M. Landry is a special counsel in the firm's Los Angeles office. He is a member of the firm's Business Trial Practice Group.
Read more about John Landry
Second Circuit Upholds Enforceability of SEC Tolling Agreements
Delaware Supreme Court Holds That Surviving "Entire Fairness" Review is Not Conclusive of a Breach of Fiduciary Duty Claim Where Directors Acted Inequitably
Delaware Court of Chancery Holds that a Contractual Delaware Choice of Law Provision Did Not Waive Plaintiff's Claim Under the California Securities Act

redpajama_set_name: RedPajamaCommonCrawl


text:
The Biggest Casualty of the Financial Crisis
Today we acknowledge a grim anniversary…
Lehman Bros. shuttered its doors 10 years ago this very day… and the Great Financial Crisis was underway.
A decade on, America is still shoveling its way out.
The stock market has gone on a run for all time, it is true.
But the Main Street economy appears to have acquired a permanent limp.
Not one year has GDP grown at 3%… while recoveries from previous recessions routinely exceeded 3%.
Meantime, the national debt pre-crisis was roughly $9.5 trillion.
The government of the United States borrowed $11.6 trillion since 2008.
Today the national debt rises above $21 trillion.
But the American economy expanded only $5.1 trillion these past 10 years.
That is, while GDP has increased 35% since 2008… the national debt has increased 122%.
The Keynesian "multiplier" has taken up division.
As "Sovereign Man" Simon Black notes… every borrowed dollar since 2008 has generated only 44 cents of economic output.
We await the breathless explanation of Paul Krugman, arch-salesman of the Keynesian business model.
We recently revealed the specific economic impact of post-2008 "unconventional monetary policy."
This includes QEs 1 through 3, NIRP, ZIRP and three-quarters of the English alphabet.
The combined results, as summarized by analyst Daniel Lacalle:
In eight of the 12 cases analyzed, the impact on the economy was negative.
In three cases, it was completely neutral.
It only worked in the case of the so-called QE1 in the U.S. and fundamentally because the starting base was very low and the U.S. became a major oil and gas producer.
For emphasis:
In 11 of 12 instances… "unconventional monetary policy" proved either negative or insignificant.
Again we turn to Torsten Slok, chief international economist at Deutsche Bank:
The conclusion is that U.S. QE1 had an impact but in all other cases the impact of QE and negative interest rates has been insignificant. And in eight out of 12 cases, the economic impact has been negative.
We re-submit the following graphic in indictment of central banks the world over:
Radical changes as those above get no hearing in normal times.
But come the crisis, we are forced to guzzle whatever medicine is on tap — however bitter — side effects be damned.
Was there a man outside the economics departments of ivied institutions who would mount a soapbox and yell for negative interest rates?
Imagine… being charged to house your money in a bank.
A fellow proposing it would have been packed off to a farm not nearly as funny as the word suggests.
But Lehman fell.
A few short years later whole swathes of the civilized world were toiling under negative interest rates.
Many still are.
Absent the great crisis, it would not have been.
Nor would the rest of the financial witchcraft conjured into being these past 10 years.
Come the next crisis…
Negative interest rates, the banning of cash, "helicopter money," etc., we will likely be treated to the entire menu — and probably more.
"The modern world is insane," said G.K. Chesterton once upon a time, "not so much because it admits the abnormal, as because it cannot recover the normal."
We have lost the normal.
Only one question remains:
Will we ever recover it?
Brian Maher
Managing editor, The Daily Reckoning
About Brian Maher:
Brian Maher is the Daily Reckoning's Managing Editor. Before signing on to Agora Financial, he was an independent researcher and writer who covered economics, politics and international affairs. His work has appeared in the Asia Times and other news outlets around the world. He holds a Master's degree in Defense & Strategic Studies.


Resident physicians who graduate from medical school typically spend three to seven years in graduate medical education (GME) training at teaching hospitals and their associated ambulatory (outpatient) settings. The CAP develops and provides high-caliber educational meetings, trainings, and workshops to support pathology and laboratory professionals.
The vast majority of GME funding comes from the federal Medicare program. The Medicare program pays for direct GME – costs of educating residents – and indirect medical education to cover the higher costs teaching hospitals incur.
The Balanced Budget Act of 1997 limited the number of allopathic and osteopathic medical residents counted for purposes of calculating Medicare reimbursement to each hospital's 1996 resident count. Additionally, the Balanced Budget Refinement Act of 1999 increased the limit for rural teaching hospitals to equal 130% of each rural teaching hospital's 1996 resident count. These caps reflect the health care workforce in 1996 and do not reflect how health care needs have changed over the past 20 years.
The CAP projects a substantially lower supply of pathologists in the next 15 years due to a projected retirement cliff. The number of physicians entering the pathology workforce each year will be far less than the number needed to keep up with the approaching retirement cliff. Pathology slots must be protected to ensure there is not an adverse impact on health care delivery. Unfortunately, there is little awareness among policymakers about the pathology retirement cliff and the impact it could have on patients. Overall GME funding needs to be maintained, if not increased, to help protect funding for residency slots for pathology.


text:
List of parishes in Louisiana
The U.S. state of Louisiana is divided into 64 parishes in the same way that 48 of the other states of the United States are divided into counties (Alaska is divided into boroughs and census areas).
Forty-one parishes are governed by a council called the Police Jury. The other twenty-three have various other forms of government, including: president-council, council-manager, parish commission, and consolidated parish/city.
Listing[change | change source]
FIPS code[1]
Parish seat[2]
Established[2]
Meaning of name[3]
Area[2]
Acadia Parish 001 Crowley 1886 from part of St. Landry Parish. Named for the Acadians who settled the area. 61,773 658 sq mi
(1,704 km2)
Allen Parish 003 Oberlin 1912 from part of Calcasieu Parish. Henry Watkins Allen, the Confederate governor of Louisiana 25,764 766 sq mi
Ascension Parish 005 Donaldsonville 1807 One of the original 19 parishes. Named for the Ascension of Our Lord Catholic Church in Donaldsonville, Louisiana 107,215 303 sq mi
(785 km2)
Assumption Parish 007 Napoleonville 1807 One of the original 19 parishes. Named for the Assumption Roman Catholic Church, the oldest in the state 23,421 364 sq mi
Avoyelles Parish 009 Marksville 1807 One of the original 19 parishes. The Avoyel Native American people 42,073 866 sq mi
Beauregard Parish 011 DeRidder 1912 from part of Calcasieu Parish. Confederate general P. G. T. Beauregard 35,654 1,166 sq mi
Bienville Parish 013 Arcadia 1848 from part of Claiborne Parish. Named after the founder of the city of New Orleans, Jean-Baptiste Le Moyne de Bienville 14,353 822 sq mi
Bossier Parish 015 Benton 1843 from part Claiborne Parish. U.S. Representative Pierre Bossier 116,979 867 sq mi
Caddo Parish 017 Shreveport 1838 from part of Natchitoches Parish. Named for the Caddo Native American people 254,969 937 sq mi
Calcasieu Parish 019 Lake Charles 1840 from part of St. Landry Parish. Calcasieu, meaning crying eagle, is said to be the name of an Atakapa Native American leader 192,768 1,094 sq mi
Caldwell Parish 021 Columbia 1838 from part of Catahoula Parish and Ouachita Parish. Named for the Caldwell family, which owned a large plantation and remains politically active in the state. 10,132 541 sq mi
Cameron Parish 023 Cameron 1870 from parts of Calcasieu Parish and Vermilion Parish. U.S. Secretary of War Simon Cameron 6,839 1,932 sq mi
Catahoula Parish 025 Harrisonburg 1808 from parts of Ouachita Parish and Rapides Parish. Catahoula Lake, formerly within the parish's boundaries and named from a Taensa word meaning big, clear lake 10,407 739 sq mi
Claiborne Parish 027 Homer 1828 from part of Natchitoches Parish. Governor of Louisiana William C. C. Claiborne 17,195 768 sq mi
Concordia Parish 029 Vidalia 1807 One of the original 19 parishes. Name is of uncertain origin; may be from an early land grant called New Concordia, from the "concord" reached by local authorities over a mutual surrender of slaves, or for a mansion called Concord which was owned by Spanish Governor Manuel Gayoso de Lemos 20,822 749 sq mi
DeSoto Parish 031 Mansfield 1843 from parts of Caddo Parish and Natchitoches Parish. Spanish explorer Hernando de Soto 26,656 895 sq mi
East Baton Rouge Parish 033 Baton Rouge 1810 from West Florida territory. French phrase bâton rouge meaning red stick. A red stick was used by local Native Americans to mark the boundaries between tribal territories 440,171 471 sq mi
East Carroll Parish 035 Lake Providence 1877 when Carroll Parish was divided. Charles Carroll of Carrollton, the last surviving signer of the U.S. Declaration of Independence 7,759 442 sq mi
East Feliciana Parish 037 Clinton 1824 when Feliciana Parish was divided. Felicite de Gálvez, the wife of Bernardo de Gálvez, a Spanish governor of the Louisiana Territory 20,267 456 sq mi
Evangeline Parish 039 Ville Platte 1910 from part of St. Landry Parish. Acadian heroine of the poem "Evangeline" by Henry Wadsworth Longfellow 33,984 680 sq mi
Franklin Parish 041 Winnsboro 1843 from parts of Carroll Parish, Catahoula Parish, Madison Parish and Ouachita Parish Founding Father Benjamin Franklin 20,767 636 sq mi
Grant Parish 043 Colfax 1869 from parts of Rapides Parish and Winn Parish. U.S. President Ulysses S. Grant 22,309 664 sq mi
Iberia Parish 045 New Iberia 1868 from parts of St. Martin Parish and St. Mary Parish. Named by Spanish settlers in honor of the Iberian Peninsula 73,240 1,031 sq mi
Iberville Parish 047 Plaquemine 1807 One of the original 19 parishes. Explorer Pierre Le Moyne d'Iberville, the brother of Jean-Baptiste Le Moyne de Bienville 33,387 653 sq mi
Jackson Parish 049 Jonesboro 1845 from parts of Claiborne Parish, Ouachita Parish and Union Parish U.S. President Andrew Jackson 16,274 580 sq mi
Jefferson Parish 051 Gretna 1825 from part of Orleans Parish Founding Father Thomas Jefferson 432,552 642 sq mi
Jefferson Davis Parish 053 Jennings 1912 from part of Calcasieu Parish. Jefferson Davis, president of the Confederate States of America 31,594 659 sq mi
Lafayette Parish 055 Lafayette 1823 from part of St. Martin Parish. French-born American Revolutionary War hero the Marquis de la Fayette 221,578 270 sq mi
Lafourche Parish 057 Thibodaux 1807 One of the original 19 parishes. Was named Interior Parish until 1812 and Lafourche Interior Parish until 1853. French phrase la fourche or in English, the fork; Bayou Lafourche, or Fork Bayou, is a fork of the Mississippi River 96,318 1,472 sq mi
La Salle Parish 059 Jena 1908 from part of Catahoula Parish. Explorer René-Robert Cavelier, Sieur de La Salle 14,890 663 sq mi
Lincoln Parish 061 Ruston 1873 from parts of Bienville Parish, Claiborne Parish, Jackson Parish and Union Parish. U.S. President Abraham Lincoln 46,735 472 sq mi
Livingston Parish 063 Livingston 1832 from part of St. Helena Parish. U.S. Secretary of State Edward Livingston 128,026 703 sq mi
Madison Parish 065 Tallulah 1838 from Concordia Parish. U.S. President James Madison 12,093 651 sq mi
Morehouse Parish 067 Bastrop 1844 from parts of Carroll Parish and Ouachita Parish. Abraham Morehouse, who led the first settlers into the region 27,979 805 sq mi
Natchitoches Parish 069 Natchitoches 1807 One of the original 19 parishes. The Natchitoches Native American people 39,566 1,299 sq mi
Orleans Parish 071 New Orleans 1807 One of the original 19 parishes. Today coterminous with the City of New Orleans. Named after the Duke of Orléans, the regent of France 343,829 907 sq mi
Ouachita Parish 073 Monroe 1807 One of the original 19 parishes. The Ouachita Native American people. 153,720 350 sq mi
Plaquemines Parish 075 Pointe a la Hache 1807 One of the original 19 parishes. A word meaning persimmons created from the Louisiana Creole French and the Mobile Native American language 23,042 2,429 sq mi
Pointe Coupee Parish 077 New Roads 1807 One of the original 19 parishes. French phrase la pointe coupée or in English, the cut-off point, which refers to a bend in the Mississippi River 22,802 591 sq mi
Rapides Parish 079 Alexandria 1807 One of the original 19 parishes. Named for local river rapids (French: rapides) 131,613 1,362 sq mi
Red River Parish 081 Coushatta 1871 from parts of Bienville Parish, Bossier Parish, Caddo Parish and Natchitoches Parish. Named for Red River, which is part of the Mississippi River watershed 9,091 402 sq mi
Richland Parish 083 Rayville 1868 from parts of Carroll Parish, Franklin Parish, Morehouse Parish and Ouachita Parish. Named for its rich land 20,725 564 sq mi
Sabine Parish 085 Many 1843 from parts of Caddo Parish and Natchitoches Parish. Named for the Sabine River and the so-called Sabine Free State 24,233 1,012 sq mi
Saint Bernard Parish 087 Chalmette 1807 One of the original 19 parishes. Saint Bernard, who was presumably the patron saint of Bernardo de Galvez, the Spanish governor who granted land to the Canary Islanders who settled the area in 1778 while Louisiana was under Spanish rule. 35,897 1,794 sq mi
Saint Charles Parish 089 Hahnville 1807 One of the original 19 parishes. Saint Charles 52,780 410 sq mi
Saint Helena Parish 091 Greensburg 1810 from West Florida territory. Saint Helena 11,203 409 sq mi
Saint James Parish 093 Convent 1807 One of the original 19 parishes. Saint James 22,102 258 sq mi
Saint John the Baptist Parish 095 Edgard 1807 One of the original 19 parishes. Saint John the Baptist 45,924 348 sq mi
Saint Landry Parish 097 Opelousas 1807 One of the original 19 parishes. Saint Landry 83,384 939 sq mi
Saint Martin Parish 099 Saint Martinville 1807 One of the original 19 parishes. Saint Martin 52,160 817 sq mi
Saint Mary Parish 101 Franklin 1811 from part of St. Martin County. Saint Mary. 54,650 612 sq mi
Saint Tammany Parish 103 Covington 1810 from West Florida territory. Legendary Indian Chief Tamanend. 233,740 1,124 sq mi
Tangipahoa Parish 105 Amite 1868 from parts of Livingston Parish, St. Helena Parish, St. Tammany Parish and Washington Parish. Comes from an Acolapissa word meaning ear of corn or those who gather corn 121,097 823 sq mi
Tensas Parish 107 Saint Joseph 1843 from part of Concordia Parish. The Taensa Native American people. 5,252 641 sq mi
Terrebonne Parish 109 Houma 1822 from part of Lafourche Parish. French phrase terre bonne or in English, good earth 111,860 2,080 sq mi
Union Parish 111 Farmerville 1839 from part of Ouachita Parish. Named for the union of states which make up the U.S. 22,721 905 sq mi
Vermilion Parish 113 Abbeville 1844 from part of Lafayette Parish. Both the Vermilion River and Vermilion Bay 57,999 1,538 sq mi
Vernon Parish 115 Leesville 1871 from parts of Natchitoches Parish, Rapides Parish and Sabine Parish. Mount Vernon, the home of George Washington, the first U.S. President 52,334 1,341 sq mi
Washington Parish 117 Franklinton 1819 from part of St. Tammany Parish. U.S. President George Washington 47,168 676 sq mi
Webster Parish 119 Minden 1871 from parts of Bienville Parish, Bossier Parish and Claiborne Parish. U.S. statesman Daniel Webster 41,207 615 sq mi
West Baton Rouge Parish 121 Port Allen 1807 One of the original 19 parishes. Was named Baton Rouge Parish until 1812. French phrase bâton rouge meaning red stick. A red stick was used by local Native Americans to mark the boundaries between tribal territories 23,788 203 sq mi
West Carroll Parish 123 Oak Grove, West Carroll Parish 1877 when Carroll Parish was divided. Charles Carroll of Carrollton, the last surviving signer of the U.S. Declaration of Independence 11,604 360 sq mi
West Feliciana Parish 125 Saint Francisville 1824 when Feliciana Parish was divided. Felicite de Gálvez, the wife of Bernardo de Gálvez, a Spanish governor of the Louisiana Territory 15,625 1,051 sq mi
Winn Parish 127 Winnfield 1852 from parts of Catahoula Parish, Natchitoches Parish and Rapides Parish. Louisiana state legislator Walter Winn 15,313 957 sq mi
Former Parishes[change | change source]
Biloxi Parish formed in 1811 from West Florida territory. It was eliminated in 1812 when part of the former West Florida area was transferred to Mississippi Territory.
Carroll Parish formed in 1838 from part of Ouachita Parish. In 1877, it was divided into East Carroll Parish and West Carroll Parish.
Feliciana Parish formed in 1810 from West Florida territory. In 1824, it was divided into East Feliciana Parish and West Feliciana Parish.
Pascagoula Parish formed in 1811 from West Florida territory. It was eliminated in 1812 when part of the former West Florida area was transferred to Mississippi Territory.
Warren Parish formed in 1811 from part of Concordia Parish, and merged into Concordia Parish and Ouachita Parish in 1814.
"Find a County". National Association of Counties. Archived from the original on 2006-11-08. Retrieved 2007-03-13. - Counties, parish seats, areas, names and date of formation of current parishes
"Louisiana County Formation Maps". Retrieved 2007-03-13. - Formation dates and origin of parishes
↑ "EPA County FIPS Code Listing". EPA.gov. Retrieved 2008-02-23.
↑ 2.0 2.1 2.2 2.3 National Association of Counties. "NACo - Find a county". Archived from the original on 2008-06-04. Retrieved 2008-06-12.
↑ "Louisiana Dept. of Public Health Parish Profiles". Archived from the original on 2005-11-17. Retrieved 2012-03-25.
Baton Rouge (capital)
Louisianians
Lieutenant Governors
Secretaries of State
Attorneys General
Congressional districts
Seal of Louisiana
Ark-La-Tex
Florida Parishes
Greater New Orleans
Northwest Louisiana
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Larger cities
Medium-sized cities
Smaller cities
Shreveport–Bossier City
Houma–Bayou Cane–Thibodaux
Avoyelles
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Louisiana parishes
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This page was last changed on 13 May 2021, at 15:00.