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Experts debate safety of ibuprofen for COVID-19
Physicians are contemplating how to best counsel patients.
ByDr. Chloë E. Nunneley,Dr. Vinayak Kumar, andSony Salzman
Inside the frantic race to find a drug to fight coronavirus
Scientists are testing whether existing FDA-approved drugs can fight novel coronavirus.
Brian Snyder/Reuters
One of the common symptoms of COVID-19 is fever, and a drug called ibuprofen, found in the leading brands Advil and Motrin, is one of the most-trusted fever reducers available without a prescription.
Early in the novel coronavirus epidemic, people were told to stock up on over-the-counter medications including ibuprofen to help reduce mild fevers if asked to ride out a viral illness at home.
But recently, French Minister Olivier Veran, a physician, tweeted that anti-inflammatory medications like ibuprofen "could be a factor in aggravating the infection," encouraging patients to take acetaminophen, which is found in Tylenol, for a fever instead.
His comments sparked a wave of controversy about the safety of ibuprofen for fevers associated with COVID-19, with experts weighing in on both sides. Although its safety is still being studied, for now, the world's leading scientists at the World Health Organization have said people shouldn't shy away from using ibuprofen to help mild fevers.
Drug companies that make over-the-counter painkillers told ABC News that they're monitoring the rapidly evolving situation and that patients should consult with healthcare providers about any concerns.
A spokesperson for Johnson & Johnson, which makes both Motrin and Tylenol, said the company "is taking all possible measures to maximize product availability across our OTC medicine portfolio to ensure broad access in all markets around the world."
A spokesperson for GlaxoSmithKline, which produces Advil, said: "This is an emerging and rapidly evolving situation, and because consumer safety is our number one priority, we are closely monitoring statements from the public health authorities and medical experts."
Concerns about ibuprofen and other fever reducers may have been kick-started by fake WhatsApp messages circulating online. While normally such claims would be ignored by medical professionals, the online conspiracy fell on the heels of a hypothesis published in a prestigious scientific journal, the Lancet, which said there may be a scientific rationale for COVID-19 patients to avoid ibuprofen.
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That theory draws on molecular biology. Because the virus that causes COVID-19 is known to bind to a specific protein in the body called ACE2, any medication that can increase ACE2, like ibuprofen, could theoretically increase the risk for a more severe COVID-19 infection.
In addition to ibuprofen, other medications like ACE inhibitors and angiotensin receptor blockers, a widely used group of blood pressure-lowering medications, have been thought to potentially increase ACE2.
But these are just theories.
Because of the thin evidence, numerous professional societies have come out against the French official's claim. One of these groups was the Infectious Diseases Society of Ireland, stating that the circulating message was "a fake message" and that patients can still take ibuprofen and other nonsteroidal anti-inflammatories for COVID-19 infections.
Ireland's Health Service Executive also said, "Regular medication, including anti-inflammatory medication, may be continued by people with COVID-19, unless advised otherwise by their healthcare professional." The Spanish Ministry of Health also said that there is no evidence that ibuprofen or other NSAIDs make the novel coronavirus worse.
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Initially, a representative for the World Health Organization reportedly said at a press conference on Tuesday that patients should use paracetamol or acetaminophen in favor of ibuprofen.
Since then, the WHO has effectively retracted that warning statement. A representative from the organization said WHO "is gathering further evidence on this issue before making a formal recommendation, but after a rapid review of the literature, is not aware of published clinical or population-based data on this topic."
However, the WHO clearly announced on Wednesday evening that it does "not recommend against the use of ibuprofen" because it is "not aware of reports of any negative effects, beyond the usual ones that limit its use in certain populations."
Nurse Corazon Morales administers a test for coronavirus disease (COVID-19) to a patient at a drive-through testing site in a parking lot at the University of Washington's Northwest Outpatient Medical Center in Seattle, March 17, 2020.
Meanwhile, prior scientific studies seem to suggest other anti-inflammatory medications might actually be beneficial. One study found that indomethacin, a drug similar to ibuprofen, may help fight SARS-CoV, a closely related virus that caused SARS. However, this study was not performed in humans.
With these conflicting reports, the public is left wondering whether medicines perhaps stockpiled stockpiled at home are the correct ones.
Physicians, too, are now contemplating how to best counsel their patients. Many, like Dr. Daniel DeSimone, an infectious disease physician at Mayo Clinic, acknowledged that the data is too limited to be certain.
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"From my review, there is no solid evidence that ibuprofen can make coronavirus symptoms and/or outcomes worse. At this time, there is no reason to avoid ibuprofen for pain or fever in COVID-19 patients," he said. "While Tylenol is typically used as a first-line agent, ibuprofen and other NSAIDS can be considered assuming they don't have an underlying contraindication such as renal disease. We will keep monitoring as more data comes in, so we will get a better grasp on the situation and deliver the best care possible to all our patients."
Dr. Simone Wildes, an infectious disease specialist at South Shore Hospital, echoed the need for additional studies.
"The use of ibuprofen in COVID-19 infection is a common question being posed by clinicians and patients," Wildes told ABC News. "More research is needed to study the effects of ibuprofen in patients with COVID-19 infection. We simply don't know the answer at this time. We need more data."
Other physicians, like Dr. Lalita Abhyankar, a family medicine physician at the Institute for Family Health, are taking a more cautious approach.
"I've been advising people that given the international concerns, it's best to treat any fever with acetaminophen instead of ibuprofen at this time. Taking it for headache or other joint pain might still be OK, we're just not sure yet because of the minimal data."
Irrespective of its questionable impact on COVID-19, doctors have said patients with kidney disease and stomach ulcers should try to minimize their use of ibuprofen. It's also not recommended in infants young than 6 months. Patients who are concerned should consult with their physicians on whether ibuprofen use is right for them in the context of their non-COVID19-related medical issues.
DeSimone encouraged the public to brace for ongoing change as experts learn more about this new virus.
"We have to realize that new information is coming in every day, and some things that we do today may be different tomorrow," DeSimone said.
Chloë E. Nunneley, M.D., a pediatric resident physician at Boston Children's Hospital and Boston Medical Center, and Vinayak Kumar, M.D., MBA, an internal medicine resident at Mayo Clinic, are contributors to the ABC News Medical Unit. Sony Salzman is the unit's coordinating producer.


"O Turkish Youth! Your first and foremost duty is to defend and protect the Turkish independence and the Turkish Republic for all eternity. All the mighty strength that you will need exists in the noble blood a-flowing in your veins!."
On August 17, 1999, western Turkey was struck by a devastating magnitude-7.4 earthquake. Many thousands of people were killed, and many more made homeless by the quake that was centered near Izmit. Contributing to the rebuilding process, ATASC initiated an effort in February 2003 to build a new school for the children of Izmit. The school admitted its first class on September 13, 2004. ATASC still continues to support its namesake school.
Since 2006, ATASC sponsored 13 needy children, helped send 6 children to Space Camp Izmir, opened up a Computer Lab and a Science Lab. Most recently ATASC helped the school to open up a pre-school by furnishing four pre-school classrooms named for ATASC chapters. VATAN Chapter is currently in the process of furnishing a conference salon for the students of the elementary school.
CLICK HERE FOR PREVIOUS EVENT PICTURES!
ATASC Celebrates BAYRAM. ATASC Bayraminizi kutlar.
© ATASC Copyright 2009. All Rights Reserved.


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UK reverses travel ban decision, removes African countries from red list
Onyinye Ubah
The United Kingdom has reversed its decision to ban flights from the 11 African countries earlier placed on red list. This decision followed a counter action by the Nigerian government to equally ban flights from the UK, Canada and other countries in retaliation.
Apart from the bold decision by the Nigerian government, there was a backlash from the likes of South African President, Cyril Ramaphosa and a good number of Africans and concerned people across the world. The concerns generally spans across the angle that, African countries were being treated "unfairly" for discovering and sharing the Omicron variant with the world.
Health Secretary, Sajid Javid who made the announcement said, "now that there is community transmission of Omicron in the UK and Omicron has spread so widely across the world, the travel red list is now less effective in slowing the incursion of Omicron from abroad."
Sajid added that, "whilst we will maintain our temporary testing measures for international travel we will be removing all 11 countries from the travel red list effective from 4am tomorrow morning."
The 11 countries earlier affected by the unfair decision were Angola, Botswana, Eswatini, Lesotho, Malawi, Mozambique, Namibia, Nigeria, South Africa, Zambia and Zimbabwe.
According to the alternative arrangement, the country decided to allow flights from the listed countries but on condition that, the travelers will self-isolate in a pre-booked government facility or hotel for at least 10 days and pay above 2000 pounds.
Following the earlier announcement by the UK government, Nigeria equally issued a communique with threats not to only ban flights from the UK, Canada and co but to also place them on red list in retaliation, effective December 14th.
Nigeria's Aviation minister, Captain Hadi Sirika said, "we have given our input that it is not acceptable by us and we recommended that those Canada, the UK, Saudi Arabia and Argentina also be put on the red list."
He added that, "as they did to us, if they do not allow our citizens into their countries; who are they coming, as airlines, to pick from our country? They are not supposed to come in. I am very sure in the next three days; Monday or Tuesday, all those countries will be put on the red list of COVID-19.''
Remembering a Hero: The Voice of Thomas Sankara
On this day in 1987, a great Pan African leader, Thomas Sankara was assassinated at
West African ECO; a mere change of name or a dream come true?
Seven West African countries have adopted their long-proposed common currency called ECO to replace the
Kenya lifts maize import ban on Tanzania and Uganda under strict conditions
Kenya lifts maize import ban on Tanzania and Uganda under strict conditions*We have reported earlier
Ghana will soon procure covid-19 vaccine – President Akufo-Addo
The President of Republic of Ghana, Nana Akufo-Addo assured the citizenry of the possibility of

redpajama_set_name: RedPajamaCommonCrawl


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What's Next For U.S. Foreign Policy?
Type: Public event
Host: Weiser Diplomacy Center, International Policy Center
Series: Weiser Diplomacy Center Series
Dec 2, 2020, 4:00-5:00 pm EST
This is a Virtual Event.
The Weiser Diplomacy Center is partnering with the American Academy of Diplomacy to bring seasoned U.S. diplomats to Ford School and discuss the future of U.S. foreign policy after presidential election 2020. We invite students and community to join us in conversation with Ambassador Ron Neumann, program moderator, with Ambassador Dawn Liberi, Ambassador Hugo Llorens and Ambassador Alexander Vershbow.
About the speakers:
Ambassador Dawn M. Liberi
Ambassador Dawn Liberi is a career member of the Senior Foreign Service, class of Career Minister, who served as U.S. Ambassador to Burundi from 2012 to 2016. Ambassador Liberi started her career in Africa where she served in five posts with USAID over a span of twenty years, focusing on key development issues. Serving as the USAID Mission Director in Nigeria (2002-2005), she managed a $100 million program of assistance and brokered a $20 million public-private sector alliance to fund community development activities. As USAID Mission Director in Uganda (1998-2002), Ambassador Liberi managed one of the largest HIV/AIDS and micro-enterprise programs in sub-Saharan Africa, helping to significantly reduce HIV/AIDS prevalence and assisting Uganda to develop high value exports.
Ambassador Hugo Llorens
Ambassador Hugo Llorens is a recently retired (December 31, 2017) U.S. Ambassador. He currently makes his home in Marco Island, Florida. On a part-time basis, he does international business and security affairs consulting. Llorens provides advice to U.S. and international firms on political, trade and investment matters pertaining to markets in Latin America, Europe, South Asia and the Western Pacific. He utilizes his 36 years of diplomatic experience and leverages his network of global contacts to enhance his clients' business prospects. He also does public speaking on leadership and foreign affairs issues, and is currently writing a book about his diplomatic experiences.
Ambassador Alexander Vershbow
Ambassador Alexander Sandy Vershbow is a Distinguished Fellow at the Atlantic Council's Brent Scowcroft Center on International Security in Washington DC. Ambassador Vershbow was the Deputy Secretary General of NATO from February 2012 to October 2016, the first American to hold that position. He frequently chaired meetings of the North Atlantic Council and other NATO committees. He was directly involved in shaping the Alliance's political response to Russia's aggression against Ukraine, in adapting NATO's strengthened deterrence and defense posture, and in deepening NATO's partnerships with non-Allies in Europe, the Middle East and Northeast Asia.
Ambassador Ronald Neumann
President, American Academy of Diplomacy
Formerly a Deputy Assistant Secretary of State, Ronald E. Neumann served three times as Ambassador; to Algeria, Bahrain and finally to Afghanistan from July 2005 to April 2007. Before Afghanistan, Mr. Neumann, a career member of the Senior Foreign Service, served in Baghdad from February 2004 with the Coalition Provisional Authority and then as Embassy Baghdad's liaison with the Multinational Command, where he was deeply involved in coordinating the political part of military actions.
Prior to working in Iraq, he was Ambassador in Manama, Bahrain (2001-2004), Deputy Assistant Secretary in the Bureau of Near East Affairs (1997-2000) with responsibility for North Africa and the Arabian Peninsula, and Ambassador to Algeria (1994 to 1997). He was Director of the Office of Northern Gulf Affairs (Iran and Iraq; 1991 to 1994). Earlier in his career, he was Deputy Chief of Mission in Abu Dhabi, United Arab Emirates, and in Sanaa in Yemen, Principal Officer in Tabriz, Iran and Economic/Commercial Officer in Dakar, Senegal. His previous Washington assignments include service as Jordan Desk officer, Staff Assistant in the Middle East (NEA) Bureau, and Political Officer in the Office of Southern European Affairs.
Ronald Neumann
Dawn Liberi
Alexander Vershbow
Hugo Llorens
diplomacy impact
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Weiser Diplomacy Center
International Policy Center
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U.S. policy in the Middle East: Human rights and/or national interests?
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Public diplomacy: A vision for 2021 and beyond
Zuzana Selcova Wiseley
Weill Hall
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zwiseley@umich.edu


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Tag: 1920s
WWII German Howitzer
Published 30 October 2019 by Ben Hansen
Clocking in at almost 26 feet in length, the German heavy field howitzer model 18 is an impressive sight to behold. After years of use in WWII on the eastern front, this howitzer was captured in the Battle of El…
Continue readingWWII German Howitzer
Wright Patterson Air Force Base and the Rise of US Air Power
Published 21 October 2017 by Mark Wallach
In 1909, the United States Army Signal Corps contracted with the Wright Company, and purchased its first airplane. In a makeshift airfield just outside of Dayton, Ohio, the newly Army-owned Wright Military Flyer was sent on a successful test flight.…
Continue readingWright Patterson Air Force Base and the Rise of US Air Power
CG Search for SS Milwaukee
Published 21 October 2017 by Jarod Riemersma
The SS Milwaukee set out on October 22,1929 from Milwaukee with 52 men and cargo headed to Grand Haven on its routine voyage across Lake Michigan. Later that day the ship would sustain damage and sink prompting a large Coast…
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General Billy Mitchell – Military Court Martial
Published 16 October 2016 by Emily Marciniak
General Billy Mitchell is most notably known for his push for US military airpower. His unrelenting commentary on the subject led to one of the most famous court martials for insubordination and his consequential resignation from the US Army. Early…
Continue readingGeneral Billy Mitchell – Military Court Martial
German Submarine UC-97
Published 14 October 2016 by Michael Lemmer
At the bottom of Lake Michigan lies the German Submarine UC-97. It was fired upon and sunk 20 miles off the shore of Grant Park in Chicago as part of a naval exercise. Before it was sunk, the submarine made…
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General Dynamics Land Systems
Published 11 October 2015 by Jordan Zondlak
When wars, national disaster, and other conflicts arise across the globe, who says a person are destined to become a soldier when they could instead become an engineer. Wartime production is equally, if not more important to supporting the U.S.…
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14.7 Nothing in these Terms shall give, directly or indirectly, any third party any enforceable benefit or any right of action against Us and such third parties shall not be entitled to enforce any term of these Terms against Us.
14.8 These Terms are governed by and construed in accordance with English law. The Courts of England shall have non-exclusive jurisdiction over any disputes arising out of these Terms. If you live outside the United Kingdom, English law shall apply only to the extent that English law shall not deprive you of any legal protection accorded in accordance with the law of the place where you are habitually resident ("Local Law"). In the event English law deprives you of any legal protection which is accorded to you under Local Law, then these terms shall be governed by Local Law and any dispute or claim arising out of or in connection with these Terms shall be subject to the non-exclusive jurisdiction of the courts where you are habitually resident.


We've been vegan for almost five years. In that time, I've been trying to find a good vegan pumpkin pie recipe. It's the only baked good that I've had a hard time replicating. I've tried tofu versions, versions with agar, and versions with cornstarch. I really disliked the tofu version and the others were fine, but not great. Generally the taste was decent, but I had a hard time getting the pies to set up properly. I always thought it was the lack of eggs. I looked forward to the Follow Your Heart Vegan Eggs, which just came out. Since you can scramble them, I thought they would work well in pie. However, the FYH vegan eggs are still very hard to find.
Then I found the "Four Ingredient Vegan Pumpkin Pie" recipe from Happy Healthy Life. This one is a keeper. Not only is it really simple, but it sets up beautifully and tastes divine. I tasted the batter before baking to adjust the spices and knew that even if it didn't set up, it would still be delicious. The four ingredients include: pumpkin, raw cashews, maple syrup and spices (pumpkin pie spice and salt). You can definitely taste the maple, but it adds a depth of flavor that I really enjoyed. We enjoyed it so much, that I made two in one week. If you don't have pumpkin pie spice, you can make your own. I found this recipe and made a bunch to use regularly. I used less ginger than the recipe called for as personal preference. What's wonderful is that you can adjust to your own personal tastes.
Making your own pie crust is not very difficult and worth the effort. I no longer use butter, but have found that a mix of Earth Balance Vegan Butter and Earth Balance Shortening works just as well. Here's a recipe for a basic pie crust.
Whisk the flour, sugar and salt until well combined.
Cut in the shortening and vegan butter. You can cube it before hand to make it easier to incorporate. A pastry blender or two butter knives work well. Cut in the fat until the flour mixture resembles cornmeal, with small bits of fat showing.
Combine the ice water and vinegar.
Drizzle 1/3 of it over the flour mixture and stir with a fork. Continue with the remaining liquid or until the dough forms a soft ball when pressed together. If it is still too dry add a tablespoon of ice water at a time until it can be gathered into a ball.
Watch the videos for tips on rolling out the crust, moving the crust and crimping the edges like a pro. I'm a visual learner, so watching someone do it is more helpful than reading about it.
You may have left over pie dough after placing the dough in your pie pan and trimming the edges. I used to throw out these little bits until my husband suggested rolling it out again and making mini cinnamon rolls! Absolutely brilliant! Just roll out the left over dough, sprinkle with sugar (brown works nicely) and some more cinnamon or pumpkin pie spice. Roll up, slice into mini rolls and bake at 350ºF for 10-15 minutes until lightly browned.


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Netflix officially comes to Ubuntu via Chrome, Linux fans rejoice!
Back in September, Netflix revealed via the Ubuntu Developers Forum that the video-on-demand service would finally be available on Linux, via the latest stable Chrome build.
Canonical has revealed that Ubuntu fully supports Netflix via the official Chrome 37 release, with no hacks, twiddles or workarounds required.


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Click here to view the official ISAGO registry.
The implementation of the IATA Safety Audit for Ground Operations (ISAGO) aims to improve safety and cut airline costs by drastically reducing ground accidents and injuries.
ISAGO is modelled on the successful IATA Operational Safety Audit (IOSA) program. The ISAGO program is an audit system conducted in a standardized and consistent manner, using internationally recognized quality auditing principles.
While airlines have similar operational practices appropriate to one common audit, things are more complex for ground handlers, covering a wide scope of activities as diverse as passenger and baggage handling, load control, cargo handling, etc.
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Politics Throwback: The Coup Speech That Overthrew Buhari in 1985
Thread starter Jules
Read the coup speech from August 27, 1985 when General Muhammadu Buhari (now President Muhammadu Buhari) was overthrown.
I, Brigadier Joshua Nimyel Dogonyaro, of the Nigerian Army, hereby make the following declaration on behalf of my colleagues and members of the Nigerian Armed Forces. Fellow country men, the intervention of the military at the end of 1983 was welcomed by the nation with unprecedented enthusiasm. Nigerians were unified in accepting the intervention and looked forward hopefully to progressive changes for the better.
Almost two years later, it has become clear that the fulfillment of expectations is not forthcoming. Because this generation of Nigerians and indeed future generations have no other country but Nigeria, we could not stay passive and watch a small group of individuals misuse power to the detriment of our national aspirations and interest.
No nation can ever achieve meaningful strides in its development where there is an absence of cohesion in the hierarchy of government; where it has become clear that positive action by the policy makers is hindered because as a body it lacks a unity of purpose.
It is evident that the nation would be endangered with the risk of continuous misdirection. We are presently confronted with that danger. In such a situation, if action can be taken to arrest further damage, it should and must be taken. This is precisely what we have done. The Nigerian public has been made to believe that the slow pace of action of the Federal Government headed by Major-General Muhammadu Buhari was due to the enormity of the problems left by the last civilian administration.
Although it is true that a lot of problems were left behind by the last civilian government, the real reason, however, for the very slow pace of action is due to lack of unanimity of purpose among the ruling body; subsequently, the business of governance has gradually been subjected to ill-motivated power play considerations. The ruling body, the Supreme Military Council, has, therefore, progressively been made redundant by the actions of a select few members charged with the day-to-day implementation of the SMC's policies and decision.
The concept of collective leadership has been substituted by stubborn and illadvised unilateral actions, thereby destroying the principles upon which the government came to power. Any effort made to advise the leadership, met with stubborn resistance and was viewed as a challenge to authority or disloyalty. Thus, the scene was being set for systematic elimination of what, was termed oppositions. All the energies of the rulership were directed at this imaginary opposition rather than to effective leadership. The result of this misdirected effort is now very evident in the country as a whole. The government has started to drift. The economy does not seem to be getting any better as we witness daily increased inflation. The nation's meager resources are once again being wasted on unproductive ventures.
Government has distanced itself from the people and the yearnings and aspirations of the people as constantly reflected in the media have been ignored. This is because a few people have arrogated to themselves the right to make the decisions for the larger part of the ruling body. All these events have shown that the present composition of our country's leadership cannot, therefore, justify its continued occupation of that position.
Furthermore, the initial objectives and programmes of action which were meant to have been implemented since the ascension to power of the Buhari Administration in January 1984 have been betrayed and discarded. The present state of uncertainty and stagnation cannot be permitted to degenerate into suppression and retrogression. We feel duty bound to use the resources and means at our disposal to restore hope in the minds of Nigerians and renew aspirations for a better future.
We are no prophets of doom for our beloved country, Nigeria. We, therefore, count on everyone's cooperation and assistance. I appeal to you, fellow countrymen, particularly my colleagues in arms to refrain from any act that will lead to unnecessary violence and bloodshed among us. Rest assured that our action is in the interest of the nation and the armed forces.
In order to enable a new order to be introduced, the following bodies are dissolved forthwith pending further announcements: (a) The Supreme Military Council (b) The Federal Executive Council (c) The National Council of States. All seaports and airports are closed, all borders remain closed. Finally, a dusk to dawn curfew is hereby imposed in Lagos and all state capitals until further notice. All military commanders will ensure effective maintenance of law and order. Further announcements will be made in due course. God bless Nigeria.
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Union Sportive Municipale de Malakoff is a football team located in Malakoff, France. It is the football section of the parent multi-sport club USM Malakoff. As of the 2020–21 season, the team plays in the Départemental 3, the eleventh tier of French football. The club's colours are blue and red.

History

USM Malakoff was founded in 1945. The highest tier the club has reached in the French football league system is the Division 2, playing in the division in the 1975–76 season. However, they finished 18th in their group and were relegated. In total, USM Malakoff played 25 seasons of football at national level from 1966 to 1991. In the Coupe de France, the club has reached round of 32 on six occasions.

In November 1953, Malakoff played in a friendly match against the Hungary national team, who were Olympic gold medalists at the time. The event attracted a significant crowd of 10,000 people at the Stade Marcel Cerdan.

Managerial history

 1949–1969:  Yves Cros
 1969–1970:
 1970–1979:  Yves Cros
 1979–????:  Yves Fercoq
 2019–????: Nouar Hassani

Honours

Notable former players

  Pierre Aubameyang
  Robert Blanc
  Gilles Bocq
  Marc Collat
  Patrick Grappin
  Maxen Kapo
  Paul Moukila

Notes

References

External links
 Club website

1945 establishments in France
Association football clubs established in 1945
Sport in Hauts-de-Seine
Football clubs in Paris

redpajama_set_name: RedPajamaWikipedia


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text:
Q: how to activate overprint and transparency flattener options in Adobe Illustrator cs6 I used to save PDF with extracted Text from Illustrator using the overprint and transparency flattener options without any problem till yesterday.
yesterday I cleaned up my PC using AVG PC TuneUp 2014 since that action I couldn't export anymore from Illustrator as extracted PDF text file.
the overprint and transparency flattener options is disabled as shown hereunder

I tried to restore all what AVG TuneUp did but nothing happened, and I get a dimmed dialogue box. And I have noticed that all software that have this option is disabled too, like indesign.
I also tried to rest all software settings to its first installed settings as usual ways but i get nothing.
my Question is how to restore or re-activate the "overprint and transparency flattener options" ?
I am using Acrobat 11 over Windows 7 ultimate and Creative Suite CS6
Note: This is not a graphics design issue, it is a technical issue.

A: One of the great feature in the "trancparency flattener options" in Adobe Illustrator is to convert all texts to outline. That feature let me work in a single file avoiding me to work in two versions of the file one with text and the other with outline texts. So When I want to export my PDF file to the printshop, I will avoid all the copyrights issues related to the font I am using and avoiding sending the font with the file to the print shop.
but this feature doesn't work without the existing of any overprint and transparency in the file. I mean I must have anything in the file that is overprinted.
The case is ... I don't have any overprint objects in my file, while I still want to export my PDF with all my texts converted to outlines while saving to PDF to prepare my file for the print shop.
I discovered recently that "overprint and transparency flattener options" " will be active if I have any overprint objects(s) in my document. which I belief it is not logic.
The trick in InDesign is: create a transparent object somewhere (where it doesn't ruin anything) and then you can run the flattener in the Save dialog. it work in Illustrator as well.

redpajama_set_name: RedPajamaStackExchange


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text:
Il Pompeo Magno è stato un incrociatore leggero appartenente alla classe Capitani Romani, settima unità in ordine di varo. Partecipò ad azioni minori nel corso della seconda guerra mondiale e, alla fine dell'estate 1943, seguì il resto della flotta da battaglia italiana a Malta secondo le disposizioni previste dall'armistizio di Cassibile. In seguito fu rischierato nel Mar Mediterraneo sotto le insegne della Marina Cobelligerante Italiana e completò missioni di supporto.

L'incrociatore fu lasciato all'Italia una volta conclusa la guerra e, negli anni cinquanta, fu estesamente modificato, riclassificato come conduttore di flottiglia e ridenominato San Giorgio con distintivo ottico D 562. Assieme al gemello  parimenti convertito entrò in servizio nella Marina Militare. Dal 1965 operante come nave scuola, fu radiato nel 1979 e demolito in seguito.

Nome e motto
La nave era intitolata al generale e politico romano Gneo Pompeo Magno (in latino: Gneus Pompeus Magnus) prima alleato e poi avversario di Gaio Giulio Cesare.

Il motto della nave Virtute duce, comite fortuna ("La virtù come guida, la fortuna come compagna") è stato tratto dalle Epistulae ad familiares di Cicerone a Lucio Munazio Planco. In precedenza era stato il motto dei sommergibili omonimi  (dismesso nel 1938) e .

Servizio operativo

L'estate 1943 e le vicende armistiziali
Il Pompeo Magno fu una delle tre unità di questa classe entrate in servizio attivo nella Regia Marina prima dell'armistizio.

La sua costruzione avvenne negli stabilimenti dei Cantieri Navali Riuniti di Ancona dove il suo scafo venne impostato il 3 settembre 1939. Varato il 24 agosto 1941 e completato il 4 giugno 1943 entrò in servizio il 24 giugno successivo. Assegnato alla base di Taranto, svolse alcune missioni di posa di mine.

Secondo alcune fonti nell'estate 1943 venne equipaggiato con radar "Gufo" EC.3ter mentre la maggior parte delle fonti concorda che solamente lo Scipione venne equipaggiato con questo tipo di radar.

Il Pompeo Magno sarebbe stato protagonista nella notte tra il 12 e il 13 luglio nelle acque dello Stretto di Messina di uno scontro con cinque motosiluranti alleate che avrebbe intercettato con il radar "Gufo" EC.3ter e sulla scorta dei dati rilevati dal radar, che non avrebbe dovuto usare "per ordini superiori", dopo aver localizzato le unità nemiche ne avrebbe affondato due in rapida successione danneggiandone gravemente una terza che sarebbe colata a picco più tardi, mentre le due rimanenti sarebbero fuggite a tutta velocità. Essendo stato nella notte tra il 16 e il 17 luglio il gemello Scipione Africano protagonista di un analogo scontro con motosiluranti nemiche sempre nelle acque dello stretto di Messina, non si può escludere, essendo stato impossibile consultare i giornali di bordo delle due unità, che si tratti di un unico episodio attribuito, da parte delle fonti, a due diversi incrociatori. Molto più probabile però che si trattasse dello Scipione, che dopo lo sbarco alleato in Sicilia, visto l'andamento delle operazioni terrestri nell'isola, in previsione di un eventuale blocco da parte Alleata dello Stretto di Messina, venne affidata la missione di forzare lo stretto e raggiungere Taranto.

All'armistizio dell'8 settembre la nave si trovava a Taranto e faceva parte insieme al gemello Scipione Africano e al Cadorna del gruppo di incrociatori alle dipendenze della V Divisione, costituita in quel momento solamente dalle Duilio.

La proclamazione dell'armistizio causò molta tensione nelle basi della Marina italiana. Il mattino del 9 settembre, dopo che intorno alle 6 lo Scipione aveva lasciato gli ormeggi dopo avere ricevuto l'ordine di raggiungere Pescara, alle altre navi della base giunse l'ordine di partire per Malta. Tra gli ufficiali della base avvenne una riunione nella quale i comandanti delle varie unità propendevano per la decisione di autoaffondare le navi. La riunione fu particolarmente drammatica: il contrammiraglio Giovanni Galati comandante il gruppo degli incrociatori, essendosi rifiutato di dirigersi a Malta, dichiarando l'intenzione di salpare per il Nord, o per cercare un'ultima battaglia, o di autoaffondare le navi, venne messo agli arresti in fortezza dall'ammiraglio Bruto Brivonesi, suo superiore, che aveva tentato invano di convincerlo ad obbedire agli ordini del Re, al quale aveva prestato giuramento. Alla fine prevalse il sentimento dell'obbedienza agli ordini del sovrano e del governo e il gruppo formato dalle due navi da battaglia, dai due incrociatori e dal cacciatorpediniere Nicoloso da Recco lasciò la base di Taranto fra le 16:00 e le 17:00, mentre era in vista la forza navale inglese che scortava il convoglio di truppe diretto a Taranto. Intorno alle 19:00 la formazione venne attaccata da quattro cacciabombardieri tedeschi che si lanciarono in picchiata sulla corazzata Duilio, sganciando bombe a poche metri dalla nave che non subì danni. Le navi reagirono con il fuoco contraereo. Alle 09:30 del giorno successivo un cacciatorpediniere inglese si mise di prora alla formazione raggiunta nel pomeriggio da otto motosiluranti che scortarono navi italiane fino a Malta, ove giunsero alle 17:50, ormeggiandosi al largo di Madliena Tower. Il gruppo guidato dall'ammiraglio Da Zara venne raggiunto dal gruppo proveniente da La Spezia, il cui comando dopo il tragico affondamento della corazzata Roma era stato assunto dall'ammiraglio Oliva.

Il periodo 1944-1945
Il 4 ottobre salpò da Malta insieme a numerose altre unità per fare rientro in Italia, e inquadrato ella VIII Divisione incrociatori nella base di Taranto, per poi passare il 2 febbraio 1944 alle dipendenze della VII Divisione incrociatori, svolgendo, durante la cobelligeranza, alcune missioni di trasporto.

Comandanti
Capitano di Vascello Paolo Mengarini dal 24 giugno al 7 agosto 1943;

Capitano di fregata Alberto Banfi dall'8 agosto 1943 al 4 settembre 1944;

Capitano di fregata Nicola Murzi dal 5 settembre 1944 al 13 ottobre 1945.

La ricostruzione

Dopo la guerra in base alle clausole del trattato di pace era previsto che fosse consegnato alla Francia in conto danni di guerra insieme ai gemelli Regolo e Scipione Africano, e il 1º maggio 1948 era stato posto in disarmo in attesa della consegna; in seguito ad un accordo avvenuto nel luglio 1948 tra i due governi vennero apportate alcune modifiche all'elenco delle navi da consegnare e il Pompeo Magno venne escluso in quanto i francesi credevano fosse afflitto da deformazioni dello scafo, che invece riguardavano il gemello Regolo, che era stato silurato nel 1942 perdendo la prora, che venne sostituita con quella del Caio Mario in costruzione, e venne deciso che il Pompeo Magno fosse cannibalizzato a favore delle altre due unità della classe da consegnare.

Evitata la consegna alla Francia, il 15 giugno 1949 completò il suo disarmo e il 15 maggio 1950 venne ufficialmente radiato dai quadri del naviglio militare, ma avendo l'Italia all'inizio degli anni cinquanta iniziato la ricostruzione della propria Marina invece di essere demolito, con Decreto del presidente della Repubblica del 1º marzo 1951, gli scafi dell'ex Pompeo Magno e del gemello Giulio Germanico, vennero nuovamente inscritti nei quadri del naviglio militare ribattezzati rispettivamente San Giorgio (D 562) e San Marco  e avviati nel 1953 a lavori di ricostruzione come cacciatorpediniere rispettivamente presso i Cantieri del Tirreno di Genova e della Navalmeccanica di Castellammare di Stabia. Al termine dei lavori il San Giorgio, rientrò in servizio nella Marina Militare Italiana nel 1955 mentre il San Marco entrò in servizio all'inizio del 1956. Il 10 aprile 1957 le due navi vennero riclassificate cacciaconduttori. Sottoposto nuovamente a lavori di modifica dal 1963 al 1965, il San Giorgio fu trasformato presso l'Arsenale di La Spezia in nave scuola per gli allievi dell'Accademia navale di Livorno, alternando crociere addestrative a una ridotta attività di squadra. Prestò servizio fino al 1979, anno in cui venne ritirato dal servizio.

Note

Bibliografia

Altri progetti

Collegamenti esterni

Pompeo Magno
Pompeo Magno
Navi costruite dai Cantieri Navali del Tirreno e Riuniti


Sunifiram is considered to be one of the most renowned recently developed nootropics available, and it also appears to have a successful future. It comprises of all the required positive effects in an emphasized form, which results proper functioning of the human brain if compared to the smart drugs like Modafinil, Ritalin and Adderall which have frequently been used to treat ADHD and other Cognitive deficit.
Is Sunifiram really this much powerful if compared to the other?
Sunifiram vs. Modafinil vs. Adderall vs. Ritalin this is something researchers are really working hard to know about. With the help of this particular post we will help you to be aware about the differences between the medications of same ingredients but different concentration.
It is an ampakine all because it is usually found triggering AMPA receptors in the brain. Some of the studies also show that the medication works like Piracetam, but the latter drug is much more powerful than sunifiram whenever taken dose for the dose.
Sunifiram, sometimes wonder whenever it comes to enhance the actual cognition, concentration, decision making capabilities and ability to retain information. There are plenty of reviewers and users say that it might become one of the best products used while studying since it really helps you to focus.
Sunifram is in the list of nootropic which was discovered and created way back in the year 2000. It is considered as imitator of Piracetam in some ways because it works like Recetam. Sinifarms works well as memory enhancer, but it is touted as a possible solution for treating mental diseases such as Alzheimer's. The First studies said that Sunifarm was better at boosting memory, and which can be done by noopept a lot to enhance your ability to concentrate and stay alert while working of studying.
Is it really fair to compare Sunifiram to Ritalin, Adderall or Modafinil? The most probable effects if considered separately, the drugs have shown common but mechanized actions in different way. Every individual knows that having Adderail, Ritalin or Modafinil (Provigil) pills will definitely make you more aware and hyper-focused.
Sunifirams commonly works upon to activate some of the same receptors which other nootropics in the Racetam family can usually do, but it really doesn't work in the same manner. Stimulation of the AMPA receptors is the main process which is completed by the Sunifrans, which is the only reason why it is a member of ampakine family.
Whenever the people were being given NBQX and then Sunifiram, there was more AMPA receptor motion recorded. As AMPA receptors monitors all the required amount of Glutamate which is created in your brain.
Glutamte is one of the brain's number one neurotransmitter which communicates excitatory transmissions, connects synapses and regulates how exactly the brain metabolizes and handles synaptic plasticity. If you have deficiency of Glutamate in your brain, it will impair your cognition. Which will result confusion and unable to pay attention to the ongoingtask.


The report organized its detailed Findings into seven major areas. I'll focus my discussions on two in particular: Technology and Work; and Education, Training, and the Labor Market.
New technologies have been replacing workers and transforming economies over the past two centuries. But, over time, these same technologies led to the creation of whole new industries and new jobs. Will the AI revolution play out like past technology revolutions, - short term disruptions followed by long-term benefits, - or will this time be different? Will there be enough work in the future? Is the US facing an age of mass unemployment, in which machines will do most of the work once reserved for human beings?
While it's impossible to predict with any certainty whether advanced technologies will destroy more jobs than they create, there's far more agreement that they've been contributing to the increased polarization of US labor markets. Given the increased technological sophistication and complexity of many work environments, demand has continued to grow for employees with good problem solving and communication skills.
At the same time, jobs dealing with more routine tasks that can be well described by a set of rules have been prime candidates for technology automation as well as for offshoring to lower-cost countries. Many blue collar jobs, such as manufacturing and other forms of production, have fallen into this category. So have white-collar, information-based activities like accounting, record keeping, and many kinds of administrative tasks. Such jobs have been steadily declining over the past few decades.
The report reminds us that education was the critical ingredient in the US becoming the world's most successful economy in the first half of the 20th century. A stream of technological breakthroughs - e.g., electricity, cars, airplanes, phones, radio, TV, computers, - increased the demand for skilled workers. The US responded by expanding public high school education and state universities.
In 1910, only 18% of 14-17 years old attended high school, and 9% graduated. Those number increased to 73% and 51% respectively by 1940, way before other countries achieved similar levels. The 1944 GI Bill offered the nation's 16 million WWII veterans payments of tuition and living expenses to attend high school, college or vocational/technical schools. By 1956 over 2.2 million had used the GI Bill to attend college or university, and 5.8 million had used it for some kind of job training program.
Economists don't generally agree on much, given the complexities of their discipline. But they're pretty much of one mind when it comes to the growing importance of skills and education in our 21st century digital economy. Education is more important than ever to keep up with the demands of a rapidly changing labor market, - not just higher levels of education, but a more targeted education that leads to better work opportunities even as the targets continue to shift during one's career.
More than one third of American adults now have college degrees. But, what about about the two thirds of the population who don't have and are not likely to get a four-year college degree? As a number of studies have pointed out, skills are in demand in a number of fields that require a post-secondary associate degree from a community college or vocational/trade school, but not necessarily a four year college degree. This demand is reflected in employment projections from the US Bureau of Labor Statistics, which shows that the median earnings of those with associate degrees is almost 20% higher than those with high school degrees, while their unemployment rate is 30% lower.
The US should set and meet a goal of bringing postsecondary education within the reach of all Americans and linking education more closely to employment outcomes.


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redpajama_set_name: RedPajamaGithub


text:
High school seniors Tiffani Torres (left) and Lorraei Forbes believe having smaller classes would be a big help at their schools.
Budget & finance Vulnerable populations
Calls for smaller class size grow louder: NYC parents, students and educators say there's a big need to rein in student seats
Manhattan high school senior Tiffani Torres started out in an AP calculus class this year with 35 students — one more than the uppermost limit high school classes are supposed to have under teacher union contracts.
It was overwhelming.
Students weren't getting proper support, and four ended up dropping the course this spring, Torres said at a City Council hearing Friday focused on class size. She contrasted it with her experience at a small middle school where she felt like she could always go to a teacher for help and she didn't have to worry about disrupting lessons with her questions.
"When there are over 30 students in a room with a single teacher, all struggling yet unable to receive the attention they need, we begin to understand how black and Latinx students are consistently left behind," said Torres, a member of Teens Take Charge, a student-led group focused on improving equity for the nation's largest school district.
Bill de Blasio pledged to lower class sizes when he campaigned for mayor in 2013. But he never delivered on that promise. New York City classes remain, on average, 15% to 30% larger than those in the rest of the state. Classes are currently capped at 25 in kindergarten, 32 for elementary grades, 33 in middle schools (though it's 30 for some of them) and 34 in high schools.
Nearly a third of New York City students were in classes of 30 or more students this fall, according to advocacy group Class Size Matters. The number of kindergarten classes with 25 or more has increased 68% since 2007, and the number of children in grades one through three in classes of 30 or more has increased by nearly 3,000%.
Many parents, educators and academics testified about the problems of overcrowding in schools — and ironically, many were barred from the hearing room because it was too crowded. Several blamed the class-size issue on the state for failing to live up to a decade-old court mandate to provide more funding to New York City.
Some pointed out that the city's priciest private schools tend to have small classes, and public schools with powerhouse PTAs often fundraise for assistant teachers in the lower grades. Meanwhile, teachers in overcrowded classes with high-needs students can often miss important signs of dyslexia or other learning disabilities, parents and educators said.
Brooklyn City Council member and former teacher Mark Treyger said that he and many others left the teaching profession because large class sizes burned them out. That's what happened to him when he had 34 students who were all English language learners.
"I think this is an issue that disproportionately affects a vulnerable population," he said.
Although the state wasn't fully funding the school system, he said, "at the same time, we can't let the city off the hook."
Class Size Matters called on City Council to earmark $100 million in next year's budget to reduce class size, starting in the early grades and in struggling schools. The amount represents less than 0.3% of the education department's $34 billion budget, noted Leonie Haimson, who runs the advocacy group. The group says it would pay for about 1,000 new teachers, and it could reduce class size in as many as 4,000 rooms.
The most influential study on class size was conducted in Tennessee during the late 1980s. The Student Teacher Achievement Ratio, or STAR, study randomly assigned students and teachers to a small class, with an average of 15 students, or to a regular class, with an average of 22 students. The achievement of students in the smaller classes translated into about three additional months of schooling four years later, according to Brookings.
Stanford's Erik Hanushek, however, has challenged this study, noting research hasn't proven academic benefits of class size reduction. He also pointed out that the study isn't widely applicable, since most schools can't get to 15 students.
New York City has never undertaken its own study on class size, Deputy Chancellor Karin Goldmark said, though she acknowledged that there is "strong" research showing the correlation between small class size and improved student outcomes. She also noted that teachers and families often cite class size as a top concern on annual school surveys.
"Do we wish class size was lower across New York City?" Goldmark asked. "We do. Do we think we can do that with the funding that we have? We don't."
Class size depends not only on the classrooms available, but also the education department's ability to recruit and retain teaching staff, Goldmark said.
"It is also an issue of funding resources. It is important to note that the current budget outlook at the state and local level is very concerning," she said. "Achieving class size reduction is contingent on funding, in particular from the state."
The state has failed to fully fund a "sound, basic education," as required by a New York State Court of Appeals decision in the Campaign for Fiscal Equity more than a decade ago, she said, saying the state owes the city $1.1 billion this year alone.
City officials said the administration allocated $640 million to reduce class size in the two 5-year capital plans under the de Blasio administration. The city's schools with the highest concentration of poverty have an average class size of 23.8 while those with the lowest concentration of need have an average class size of 28.4.
Additionally, the current five-year capital plan provides $18.8 billion to create approximately 88 new school buildings and more than 57,000 seats, officials said.
But the city needs the money owed from the state to further reduce class size, Goldmark said. (The state disagrees with this interpretation and Gov. Andrew Cuomo wants to change the funding formula entirely.)
Goldmark is also a former teacher. Her first year, she taught a class of 36 students. Later in her career, she had a class of 18. There was indeed a "big" difference.
"I wish it could have been the reverse," she said, explaining how she would have found it easier as a new teacher with a smaller class, and said that principals often make those kinds of decisions on the school level — when they're able to.
The education department this year charged superintendents with responding faster to class size issues, since enrollment projections sometimes fall short of the actual number of students who register at many schools.
"You never quite know how many children you will have on the first day," Goldmark said. "Every year we have more children in some schools and fewer in others."


Why I don't understand cooking shows.
Come Dine with Me. The Great British Bake Off. Masterchef.
Yes, it's official- Britain's obsession with cookery shows has gone completely over the top!
Cookery programmes have never been more popular, and it seems that the whole country is watching them.
Everyone, that is... except me.
I just don't get cooking shows. Why oh why oh WHY would people would want to watch other people making and eating food??
And don't get me wrong, I'm a girl with a healthy appetite!
I just don't want to watch other people cooking, judging or eating food- that's simply not entertaining for me. And actually, I find it strange that Britain has such an unhealthy attitude to food. On the one hand, we're obsessed with fancy dining and eating foods we consider part of an aspirational lifestyle- but on the other, we're a nation that gorges itself on obscene junk food like McDonalds, Burger King and Subway week in, week out. It just doesn't add up.
We gaze in wonder at stick-thin anorexic models who are clinically underweight, but at the same time just can't cram enough chips in our mouths. In short, our attitude -as a nation- towards food is ridiculous.
And if we want to change this, we have to be realistic about the kind of food we want to eat- which means LESS of these weird aspirational cookery shows like Come Dine with Me and MORE balance in our diets, and our lives.
Comment if you disagree- I know a lot of people really like all these TV shows about food (or at least I'd assume so, judging from the amount of them that Channel 4 keep producing!), so comment if you think I'm wrong!
Life lessons: Not getting what you want!