text:
Pharmaceutical Products & Market
Total rare diseases funding by the National Institutes for Health 2013-2020
Published by Matej Mikulic, Sep 5, 2019
Rare diseases funding by the NIH was around 4.6 billion U.S. dollars during fiscal year 2017. This graph shows the actual rare diseases funding by the National Institutes for Health (NIH) from FY 2013 to FY 2018 and estimates for FY 2019 and FY 2020.
Total rare diseases funding by the National Institutes for Health (NIH) from FY 2013 to FY 2020 (in million U.S. dollars)
Funding in million U.S. dollars
This statistic displays the annual support level based on grants, contracts, and other funding mechanisms used across the National Institutes of Health (NIH).
* Estimated.
Orphan drugs
Top 50 pharmaceutical companies - Rx sales and R&D spending 2019
Total global pharmaceutical R&D spending 2012-2026
Top global companies by orphan drug revenues 2018
Top global orphan drugs by revenue 2018
Matej Mikulic
Research expert covering health, pharma & medtech
Statistics on "Orphan drugs"
Prevalence of selected rare diseases worldwide 2017
Overview of rare diseases worldwide and in the U.S. as of 2016
Impact of medicines on life expectancy for select rare diseases worldwide as of 2017
Distribution of U.S. patients with rare factor deficiencies as of 2020, by gender
Projection of global revenue for orphan prescription drugs 2012-2026
Annual growth in global revenue for prescribed orphan drugs 2011-2024
Price comparison of most expensive drugs U.S. 2020
Annual average cost of orphan drugs per patient 2014-2018
Global cell and gene therapy market share by therapy class 2019 & 2025
Global rare disease diagnostics market size 2018 vs. 2025 projection
Top 10 companies by global revenue from orphan drugs 2024
Market share of top 20 companies for orphan drugs worldwide 2018 and 2024
US and European private VC-backed orphan biopharma company M&A values 2014-2019
Projection of top 10 orphan drugs by global revenue 2024
Number of orphan designations accepted in the U.S. 2003-2020
Oncology or orphan drug share in approved new active substances globally 2009-2018
FDA approved orphan drugs with non-orphan indications 1983-2018
Percentage of select orphan drug US sales by non/orphan use 2017
Leading orphan drugs in development based on net present value 2020
Global therapeutic pipeline for non-oncology orphan drug programs by company 2019
Time from orphan drug design to final exclusivity 2018, by current status
Total neurodegenerative funding by the National Institutes for Health 2013-2020
Total minority health funding by the National Institutes for Health 2013-2020
Total health disparities funding by National Institutes for Health 2013-2020
Total genetics funding by National Institutes for Health 2013-2020
Total nutrition research funding by the National Institutes for Health 2013-2020
Total human genome funding by National Institutes for Health 2013-2020
Total cancer funding by National Institutes for Health 2013-2020
Brain disorders funding by National Institutes for Health 2013-2020
Total neuroscience funding by the National Institutes for Health 2013-2020
Total infectious diseases funding by the National Institutes for Health 2013-2020
Behavioral and social science funding by the National Institutes for Health 2013-2020
Total immunization funding by National Institutes for Health 2013-2020
Total aging funding by National Institutes for Health 2013-2020
Total prevention funding by the National Institutes for Health 2013-2020
Number of slave embarkations during the intra-American slave trade 1526-1841
Real alcohol & tobacco consumer spending forecast in New Zealand 2010-2025
New business registration forecast in Tunisia 2010-2025
Tourism sector GDP share forecast in Bahrain 2010-2025
International tourist arrivals forecast in Laos 2010-2025
Orphan drugs Global pharmaceutical industry Pharmaceutical industry in the U.S. Top pharmaceutical drugs Diseases
NIH. (April 19, 2019). Total rare diseases funding by the National Institutes for Health (NIH) from FY 2013 to FY 2020 (in million U.S. dollars) [Graph]. In Statista. Retrieved January 22, 2021, from https://www.statista.com/statistics/713320/rare-diseases-funding-by-the-national-institutes-for-health/
NIH. "Total rare diseases funding by the National Institutes for Health (NIH) from FY 2013 to FY 2020 (in million U.S. dollars)." Chart. April 19, 2019. Statista. Accessed January 22, 2021. https://www.statista.com/statistics/713320/rare-diseases-funding-by-the-national-institutes-for-health/
NIH. (2019). Total rare diseases funding by the National Institutes for Health (NIH) from FY 2013 to FY 2020 (in million U.S. dollars). Statista. Statista Inc.. Accessed: January 22, 2021. https://www.statista.com/statistics/713320/rare-diseases-funding-by-the-national-institutes-for-health/
NIH. "Total Rare Diseases Funding by The National Institutes for Health (Nih) from Fy 2013 to Fy 2020 (in Million U.S. Dollars)." Statista, Statista Inc., 19 Apr 2019, https://www.statista.com/statistics/713320/rare-diseases-funding-by-the-national-institutes-for-health/
NIH, Total rare diseases funding by the National Institutes for Health (NIH) from FY 2013 to FY 2020 (in million U.S. dollars) Statista, https://www.statista.com/statistics/713320/rare-diseases-funding-by-the-national-institutes-for-health/ (last visited January 22, 2021)


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Q: Using a Variable from a Separate Function in Swift I am learning Swift and attempting to make use of code from the iOS8 Swift Dev's Cookbook, but am having difficulty using a variable produced from a custom function in the viewDidLoad function to put that product in a UILabel object.
The optional phone toward the top is not corresponding to the phone created peoplePickerNavigationController function. Thus, the labelPhone object displays nothing rather than displaying the phone number selected out of the peoplePickerNavigationController function.
How does one get a variable/constant from one function into an object in the viewDidLoad function so that it can be used in the UI?
For reference, my Storyboard contains a UIButton "Contacts" that can be tapped to execute the peoplePickerNavigationController function.
import UIKit
import AddressBookUI

class ViewController: UIViewController, ABPeoplePickerNavigationControllerDelegate {

    var phone : String?
    //I'm trying to pull up the phone variable down below, but the two are not corresponding. The optional above is what appears in the `labelPhone` object below rather than the contents of the phone way below.

    override func viewDidLoad() {
        super.viewDidLoad()
        // Do any additional setup after loading the view, typically from a nib.

        var labelPhone = UILabel(frame: CGRectMake(0, 0, 200, 21))
        labelPhone.center = CGPointMake(160, 284)
        labelPhone.textAlignment = NSTextAlignment.Center
        labelPhone.text = phone
        self.view.addSubview(labelPhone)

    }

    override func didReceiveMemoryWarning() {
        super.didReceiveMemoryWarning()
        // Dispose of any resources that can be recreated.
    }

    let personPicker: ABPeoplePickerNavigationController

    required init(coder aDecoder: NSCoder) {
        personPicker = ABPeoplePickerNavigationController()
        super.init(coder: aDecoder)
        personPicker.peoplePickerDelegate = self
    }

    func peoplePickerNavigationControllerDidCancel(peoplePicker: ABPeoplePickerNavigationController!) {
        /* Mandatory */
    }

    func peoplePickerNavigationController(peoplePicker: ABPeoplePickerNavigationController!, didSelectPerson person: ABRecord!, property: ABPropertyID, identifier: ABMultiValueIdentifier) {
        /* A property in a person was picked */
    }

    @IBAction func performPickPerson(sender : AnyObject) {
        self.presentViewController(personPicker, animated: true, completion: nil)
    }

    func peoplePickerNavigationController(peoplePicker: ABPeoplePickerNavigationController!, didSelectPerson person: ABRecordRef!) {
        /* Do we know which picker it is? */
        if peoplePicker != personPicker{
            return
        }

    /* Get all phone numbers this user has */
        let phones: ABMultiValueRef = ABRecordCopyValue(person, kABPersonPhoneProperty).takeRetainedValue()

        let countOfPhones = ABMultiValueGetCount(phones)

        for index in 0..<countOfPhones{
            let phone = ABMultiValueCopyValueAtIndex(phones, index).takeRetainedValue() as String

            println(phone)

        }
    }

}

Thanks <3
Current code:
import UIKit
import AddressBookUI

class ViewController: UIViewController, ABPeoplePickerNavigationControllerDelegate {

var phone : String?
var labelPhone: UILabel?
override func viewDidLoad() {
    super.viewDidLoad()
    // Do any additional setup after loading the view, typically from a nib.

    labelPhone = UILabel(frame: CGRectMake(0, 0, 200, 21))
    labelPhone!.center = CGPointMake(160, 284)
    labelPhone!.textAlignment = NSTextAlignment.Center
    labelPhone!.text = phone
}

override func didReceiveMemoryWarning() {
    super.didReceiveMemoryWarning()
    // Dispose of any resources that can be recreated.
}

let personPicker: ABPeoplePickerNavigationController

required init(coder aDecoder: NSCoder) {
    personPicker = ABPeoplePickerNavigationController()
    super.init(coder: aDecoder)
    personPicker.peoplePickerDelegate = self
}

func peoplePickerNavigationControllerDidCancel(peoplePicker: ABPeoplePickerNavigationController!) {
    /* Mandatory */
}

func peoplePickerNavigationController(peoplePicker: ABPeoplePickerNavigationController!, didSelectPerson person: ABRecord!, property: ABPropertyID, identifier: ABMultiValueIdentifier) {
    /* A property in a person was picked */
}

@IBAction func performPickPerson(sender : AnyObject) {
    self.presentViewController(personPicker, animated: true, completion: nil)
}

func peoplePickerNavigationController(peoplePicker: ABPeoplePickerNavigationController!, didSelectPerson person: ABRecordRef!) {
    /* Do we know which picker it is? */
    if peoplePicker != personPicker{
        return

    }

/* Get all phone numbers this user has */
    let phones: ABMultiValueRef = ABRecordCopyValue(person, kABPersonPhoneProperty).takeRetainedValue()

    let countOfPhones = ABMultiValueGetCount(phones)

    for index in 0..<countOfPhones{
        //let phone = ABMultiValueCopyValueAtIndex(phones, index).takeRetainedValue() as String

        phone = ABMultiValueCopyValueAtIndex(phones, index).takeRetainedValue() as? String
        labelPhone!.text = phone

        println(phone)

    }
}

}

A: First, viewDidLoad only execute once when the view is loaded. To change the text of the label you need to do something like:
var phone : String?
var labelPhone: UILabel?

override func viewDidLoad() {
    super.viewDidLoad()
    // Do any additional setup after loading the view, typically from a nib.

    labelPhone = UILabel(frame: CGRectMake(0, 0, 200, 21))
    labelPhone.center = CGPointMake(160, 284)
    labelPhone.textAlignment = NSTextAlignment.Center
    self.view.addSubview(labelPhone)
}

func peoplePickerNavigationController(peoplePicker: ABPeoplePickerNavigationController!, didSelectPerson person: ABRecordRef!) {
    // Got the phone
    phone = ABMultiValueCopyValueAtIndex(phones, index).takeRetainedValue() as String
    labelPhone.text = phone
}

redpajama_set_name: RedPajamaStackExchange


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text:
'Gutless': Ottawa Senators captain Brady Tkachuk reacts following biting incident
Published Sunday, November 28, 2021 10:13AM EST Last Updated Sunday, November 28, 2021 10:32AM EST
Ottawa Senators left wing Brady Tkachuk (7) gets into a brawl with Los Angeles Kings left wing Brendan Lemieux (48) and center Blake Lizotte (46) in the third period of an NHL hockey game Saturday, Nov. 27, 2021, in Los Angeles. (AP Photo/Kyusung Gong)
OTTAWA -- Ottawa Senators captain Brady Tkachuk has accused the L.A. Kings' Brendan Lemieux of biting him during a scuffle in Saturday night's game in Los Angeles.
Tkachuk and Lemieux got into a fight in the third period, at which point Tkachuk said Lemieux bit him on the hand. Lemieux was given a match penalty following the incident.
Speaking to the media following the game, Tkachuk could barely contain his contempt.
"I think it is the most gutless thing somebody could ever do," Tkachuk said. "This guy is just—you could ask any of his teammates, nobody wants to play with him—this guy is a bad guy, bad teammate. Guy's a joke. He shouldn't be in the league. The guy's gutless."
The incident began after Tkachuk shoved Blake Lizotte following a whistle with 6:09 left in the third period. Lemieux came in and he and Tkachuk began fighting, eventually falling to the ice with linesmen attempting to pull the two apart. That's when Tkachuk, showing a bleeding hand to officials, said Lemieux bit him.
"I can't really wrap my head around it. Children don't even do this. This guy's just a bad guy and not even a good player, either," Tkachuk told reporters. "It's outrageous."
Kings head coach Todd McLellan addressed the incident after the game.
"First of all, it's wrong, if it did happen. We don't want it to happen," he said. "And two, it's not a good situation to put the team in, not only tonight but moving forward."
McLellan said Lemieux has become a valuable player and he needs to understand that.
"If we happen to lose him for any period of time, we'll miss him, and he has to understand how valuable he's become."
The NHL's Department of Player Safety said Lemieux has been offered an in-person hearing via Zoom. The date and time has yet to be announced.
Los Angeles' Brendan Lemieux has been offered an in-person hearing via Zoom for Biting Ottawa's Brady Tkachuk. Date and time TBD.
— NHL Player Safety (@NHLPlayerSafety) November 28, 2021
The Kings defeated the Senators 4-2 to snap a five-game skid, while handing the Sens their fifth straight loss.
The Senators host the Vancouver Canucks Wednesday at the Canadian Tire Centre.
--With files from TSN 1200 and The Associated Press.
Ottawa Senators fall to L.A. Kings 4-2 for fifth straight loss

redpajama_set_name: RedPajamaCommonCrawl


The TELL-OP team presented some of the Intellectual Outputs being developed in the framework of the project. The day started with a welcoming and presentation of the workshop aims from Profs. Pilar Aguado and Sandra Götz, followed by our keynote speaker, John Traxler….


Need to know the best time to see gorillas in Rwanda? Rwanda is located in the central part of Africa bordered by Uganda, Tanzania, Burundi and Congo. The country boasts with gigantic landscapes that's given it a name a country of a thousand hills or the Switzerland of Africa. The most sought tourists activity here is Rwanda gorilla trekking. The best time to encounter these great apes sharing 98% of their DNA with humans can be seen below. The minimum age for gorilla trekking in Rwanda is 15 years.
June to September: This is the peak season and the longest dry season in Rwanda. It is apparently the best time to see gorillas in Rwanda. Getting to the parks is easy and the hiking trails are not muddy and slippery. There are also no chances of rain during the gorilla trekking. Tourists coming to trek gorillas in Rwanda during this time must book their gorilla permits in advance as there is very Huge demand fr permits during this time. Booking will also require paying 30% of the full price of the gorilla trekking permit.
December to February: I would also consider this the best time to see gorillas in Rwanda. This is the short dry season in Rwanda also the one of the best time to trek the endangered mountain gorillas in Rwanda. The parks are not very crowded as in June to September, gorilla trekking trails are also easy to access in this period and birding is at its peak because migratory birds are present.
April – May: This is the longest rain season in Rwanda, there are very high chances of rain falling during the trek hence spoiling your entire encounter. Gorillas can easily be found during this time because they tend to move away from very high mountain temperatures and descend to lower slopes.
October – November: This is when the short rains occurs in Rwanda. This period offers great photography opportunities and also turns out to be the best time for birding as plants are flowering. The wild is simply magical though when rain falls, they often fall at night and the skies are clear by morning.
Gorilla trekking in Rwanda costs $1500. This price doesn't change for the low and dry seasons. Your accommodation while trekking gorillas will always depend on tourists choice and budget. There are various accommodation facilities ranging from budget, mid-range and luxury, all providing good quality service to visitors.
Tourists visiting mountain gorillas during the rainy season should come along with cotton clothing, water proof hiking boots, garden gloves, insect repellents as mainly insect breed in the rainy season. Visiting during the dry season will require carrying sun glasses and sun screens. Binoculars are also advisable for bird lovers.
Please visit Rwanda and visit the endangered mountain gorillas and also engage in many other tourists activities like Golden monkey trekking, chimpanzee trekking, wildlife watching, mountain climbing, birding and so much more.


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Hi-Tech's fire and smoke simulations aids in investigating fire/smoke propagation, their effects, risk potential in different environmental and boundary conditions of the building. This simulation further aids in optimization of fire mitigation systems, ventilation systems and safety procedures.
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Reach out to Hi-Tech CAE for fire and smoke modeling and analysis at info@hitechcae.com.


Sourdough Bialys | Cooking is Fun … Really!!
They look fantastic! I wish I had the time and patience to feed sourdough starters, but I spend enough time and effort rinsing and drying various beans three times a day while they are sprouting. What one wouldn't do for one's loved ones!
Once you've got an active starter, all it takes is five minutes once a week or once every 2 weeks, depending on how often you bake. I keep mine in the fridge. And, having dried some, when I want to take a break for 6 months or so, I can do it.
And how do you make an active starter?
As you know, a sourdough starter is a mixture of acid loving yeast and bacteria similar to that used in beer or yogurt fermentation which is naturally found on wheat kernels in the field. It usually takes two weeks to develop and involves discarding part of the mixture and feeding with fresh flour and water.
I like the method shown in this YouTube video because there's minimal wastage involved by keeping quantities low and starting with a slightly acidic liquid (canned NOT fresh pineapple juice) which reduces the stinky starter stage as bacteria grow profusely and then dies and whole wheat flour, being less processed, starts out with more yeast from the wheat kernels and is more nutritious than all purpose or bread flour.
I would use a small (half cup) glass jar with a lid rather than the small cups with saucer that she uses. Having 2 jars of the same size makes it easier to transfer to a fresh jar while washing the previous one. Once you have a strong active starter, you can keep it in the fridge and only feed once a week or once every two weeks.
Thank you so much for the link and the detailed explanation! Now I have to do my research in terms of gluten content.
They look deliciously wonderful! I love the texture of bagels so I'm certain I would love these too! And they are soooo much easier in that you don't have boil a giant pot of water!
I've been told that the texture suffers from keeping (they get very hard) though so they should be eaten the same day they're baked. Perhaps that's why they haven't caught on as much as bagels have. I froze a dozen of them since I had too much bread in the house already.
I personally like a bialy better than a bagel as they aren't are heavy.
It was my first time trying them … not sure I'd make them again for a while.
Happy New Year A_Boleyn! I see you are extremely creative, as always! They look delicious and very mysterious. I've never heard about them (it's probably a regional thing), not to mention eating them….
I've never heard of a bialy before, but your pictures make me want one or two or three. I'm such a sucker for a good bread, especially bagels, I know I would love this.
Thank you for commenting. The variety of bread products across the world is truly amazing.


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Thomas 'Tom' Joe Long, age 80, of the Gaines Community, WV, died Monday, December 17, 2012, at the Louis A. Johnson VA Medical Center in Clarksburg, WV. He was born in Upshur County, WV on March 6, 1932, a son of the late Joe A. and Ruth Hamner Long. On August 30, 1952, he was united in marriage to Naomi C. 'Peg' Heater Long, who preceded him in death on December 27, 2005. He is survived by one daughter, Dianne Long of Beaver Falls, PA; one son, Burlin R. Long and wife Kim of Rochester, PA; two grandchildren, Andrea and husband Brandon Daniels and Amanda Radaker; four sisters, Martha and husband Richard Leuszler of Amherst, OH, Barbara and husband Larry Ferren of Shinnston, WV, Rita and husband Carl Watson of Walkersville, WV, and Caroline Long of Buckhannon, WV; four brothers, Dale Long of Gaines, WV, John Long and wife Cheryl of Gaines, WV, Basil Long of Gaines, WV, and Donald Long and wife Martha of Arlington, WV; and several nieces and nephews. He was preceded in death by one sister, Ellen Jean Bennett, and three brothers, Andrew Dixon Long, Burl Long, and Davis Ross Long.
Mr. Long was a member of the Rochester Lodge No. 229 F&AM and the Salem Ridge United Methodist Church. He served in the Pittsburgh International Guard. He was a sergeant in the U.S. Air Force serving during the Korean War. He retired as a General Foreman from ARMCO Steel in Ambridge, PA, with 36 years of service. Tom liked the outdoors, and had many beagles named 'Mike'. He enjoyed piloting airplanes and will be sadly missed by family and friends.
The family will receive friends today, December 19, 2012, from 3 to 7 p.m., at the Heavner and Cutright Funeral Chapel, Buckhannon, WV. The body will lie in state on Thursday, December 20, 2012, from 10 to 11 a.m., the funeral hour, at the Salem Ridge United Methodist Church with Pastor David Jessie officiating. Interment will follow in the Salem Ridge Cemetery, where the Buckhannon VFW Post #3663, the Frank B. Bartlett Post #7 American Legion, and the DAV Chapters #5 and #36 will conduct military honors. Online condolences may be extended to the Long family at www.heavner andcutright.com. The Long family has entrusted the HEAVNER & CUTRIGHT FUNERAL CHAPEL with the arrangements.


text:
U.S. Navy's next-gen advanced arresting gear system starts performance testing with Goshawk
09:32 (GMT+0000) August 28, 2019
in Maritime Security, News
Photo courtesy of U.S. Navy
The U.S. Naval Air Systems Command has announced the T-45C Goshawk aircraft began Navy's next-generation Advanced Arresting Gear (AAG) performance testing at the Runway Arrested Landing Site (RALS) located at Joint Base McGuire-Dix-Lakehurst, New Jersey.
The new advanced arresting gear system, or AAG, will replace the traditional arresting cable on the Ford-class aircraft carrier flight deck.
Series of testing with Goshawk jet trainer ensures the new recovery system can support the USS Gerald R. Ford (CVN 78) air wing.
In April, the trainer aircraft completed 60 arrestments at RALS during a five-day, risk-reduction test period utilized to evaluate AAG system integrated performance. By the end of this year, the AAG Program is scheduled to release formal approval authorizing T-45 Type Model Series aircraft flight operations on CVN 78.
The AAG system is designed to arrest a greater range of aircraft, reduce the fatigue impact load to the aircraft, and provide higher safety margins while reducing manpower and maintenance.
According to a recent report, the Navy's next-generation AAG systems also will work with propeller aircraft: C-2A Greyhound, E-2C Hawkeye and E-2D Advanced Hawkeye, and jet aircraft: F/A-18E/F Super Hornet and EA-18G Growler to perform flight operations aboard USS Gerald R. Ford (CVN 78).
General Dynamics provides Littoral Combat Ship's weapon systems upgrade details
General Dynamics Mission Systems, a subsidiary of General Dynamics, revealing more details about the upgrade of Independence-variant Littoral Combat...
U.S. Navy newest aircraft carrier begins aircraft compatibility testing
Sikorsky, Rheinmetall submit proposal for Germany's new heavy lift helicopter
U.S. Air National Guard F-16 fighters receive new APG-83 radar


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Fanny Crosby is one of the greatest American hymn writers of all time, writing songs such as Blessed Assurance, To God Be The Glory and many others that have been sung in churches across the world for more than 100 years.
Even though there have been a multitude of hymnbooks and recordings of her songs, there were over 2,000 unpublished works written by Fanny Crosby, in the vaults of Wheaton College. Those works have now been made available to a select gathering of key worship songwriters, creating a new collection of never recorded songs along with a new recording of Blessed Assurance.
This unique project is releasing on the centennial of Fanny Crosby's death, a unique and talented songwriter with a heritage that has been re-ignited.


text:
A Tale Of Two Travel Opportunities: How To Handle Being More Jet Set Than Your Partner
Alexandra Talty Contributor
Be mindful of your privilege. People have different experiences, don't lord it over them
Traveling as a couple can a big test for the relationship. If you can't vacation well together, it might be a sign for the future.
But couple travel can be difficult, especially if partners come from different financial backgrounds.
Traveling as a couple can be difficult, especially when you're from different financial backgrounds.
Although it's much more fun to post sunset photos with #wanderlust underneath than talk about travel privilege, it is is real thing. And navigating that can be difficult on your first trip. Here's how two couples from different financial backgrounds have been able to explore together, without leaving one person behind.
'My family was broke'
Max (L) felt insecure about not having traveled until he met Anthony (R) a gay budget traveler extraodinare. Together, the couple has been able to explore places like Puerto Rico's Vieuqes island.
Travel histories
From Lowell, Massachusetts, Max, 28, would visit relatives in locations like Niagara Falls, New Hampshire or Maine, but his family couldn't afford vacations to more exotic locales. Max says, "I always wanted to travel and I always felt shameful that I hadn't, especially after graduating college."
As a kid, Anthony was always "scheming to find deals to travel." His family of seven took annual vacations together; he fondly remembers a road trip down the California coast. During high school and college, he participated in and organized mission trips through his local church in Rochester, New York, visiting Haiti, Mozambique and South Africa. "I got really comfortable being in the middle of nowhere, logistically. It gave me the confidence," says Anthony, 31.
First trip together
They spent a weekend in Fort Meyer, Florida at one of Anthony's family members's condo for their first couples trip. They traveled in the shoulder season because Anthony wanted to show Max that travel doesn't have to break the bank.
"I am someone who gets off on cheap travel and good travel value," says Anthony. "It is a ritual cleansing to me. To get on a plane and breath different air and be in a different time zone."
When the couple passed their first test together, Max started joining Anthony on business trips. At the time, Anthony was traveling a lot for work so when he ended up in a fun destination like Southern California or Washington, D.C., they would tack on a weekend together. Max enjoyed having some time to himself to explore while Anthony was working, he thinks that helped him get his sea legs for their first big adventure.
Convincing your partner (and their parents) for the first international trip
Although they had previously traveled to Puerto Rico together, the first overseas trip to Bali felt like a big step for the couple. Anthony was especially worried about convincing Max's mom that he would take care of her son. By taking smaller jaunts around the states before their big international trip, they eased Max's family into the idea of him being far away...although that didn't stop her from Facetiming the couple in the Doha airport while they were en-route to Bali.
The trip was in honor of Anthony's 30th birthday. He wanted a big ticket item and went into planning overboard, even checking the inflight meals to assuage some of Max's concerns.
"If you're going to make me fly 24 hours around the world, you're going to do some planning," says Max.
Although sometimes, the less traveled partner enjoys being the planner, for Max, it helped that Anthony took the lead. Anthony poured over information about local SIM cards, as well as aspects of gay travel. This was particularly stressful leading up to their Indonesia trip, as being gay occupies a legal gray area in the country.
Using resources like Out Traveler, Anthony realized that tourist hot spot Bali has plenty of safe and affirming spaces. Anthony also uses Lonely Planet's LGBTQ recommendations, as well as the website Gay Cities for other gay travel recommendations.
Advice for the lesser traveled partner
"Don't be intimidated," says Max. "You learn a lot about your partner."
Advice for the more well traveled partner
" Be mindful of your privilege. People have different experiences, don't lord it over them ," says Anthony. "I really feel like the way we did it was the right way, start small, start easy, learn how to travel with someone; that stuff doesn't happen overnight."
'I am always traveling for work'
Angel (L) and Sheila (R) on a recent cruise from Florida to New York. Angel had a business trip that week, so Sheila came down and met him for a weekend of traveling as a couple.
Angel.
Angel was the less experienced adventurer when he first met his wife Sheila. Her family valued travel when she was growing up, and she slowly introduced Angel to the idea.
But now Angel, 30, works for an international textbook company that is headquartered in Paris, France. Between annual meetings in Europe and monthly work trips around the United States, Angel is nearly always on the road. His wife Sheila, 31, works for New York City, and has a very regulated vacation policy, so it can be hard for the couple to find time to explore together since his business trips are often last minute.
First big trip together
The couple was married on a cruise ship headed to the Caribbean, over five years ago. They invited their 45 closest friends and family along for the ride; they now go on a similar cruise every year with the same guest list to remind them of their big day.
How to make room for romance…on your business trip
Before Angel leaves on a business trip, his wife scours the internet for restaurants, sightseeing spots and fun itineraries for wherever he is headed. Domestically, his work takes him to cities like Boston, Los Angeles, Miami, Chicago or San Francisco, although he's also gone on business trips to exotic locales like Brazil.
Since she loves to travel, it's a treat for her to check out a new destination…even if she's not the one going. Angel will take her recommendations, sometimes calling his wife while he's enjoying the food at a restaurant she found online. It helps to keep them connected and Angel loves that he gets to explore with his wife, even when he's alone.
However, his wife has one rule: don't visit any of the romantic sights.
In Paris, this meant that Angel couldn't go to the top of the Eiffel Tower or the former lock bridge. They are saving those activities for when they are able to jump on a plane together.
Advice for the business traveler
Angel recommends involving your partner in the trip; it makes it feel like you're spending time together even if you aren't.
While in France, Sheila recommended a stop at the Louvre to Angel, something he admits he wouldn't have done without her encouragement.
"She pushes me," says Angel. "If it weren't for her and I had this job, I would go to the hotel and work."
Advice for the plus one
On a recent getaway to Santa Monica, Sheila was able to take time off and fly out for a long weekend. Angel went on nearly every ride on the famous Santa Monica pier before her arrival, but saved the Ferris Wheel for his wife. When he picked her up from the airport, he literally had the tickets in hand. It was their first stop together in California.
This is the third post in a series on travel privilege. The others in the series include:
I Was So Insecure About Being 30 And Going To Europe For The First Time
A Tale Of Two Travel Opportunities: When You Have A Different Passport Than Your Partner
Alexandra Talty
Based in Lebanon, I cover travel and personal finance topics for millennials. I'm committed to a life of adventure and have lived in four countries before turning 30. My...


Then came the weekly SHC listserv, a mammoth e-mail (E-mail! We know!) announcing everything from new courses and research opportunities to lectures and the annual Date Auction.
The format here may be different but the idea is still the same: to keep you informed about news and events in the SHC.
Information on upcoming events for Scholar alumni and friends, including fall reunion events, Homecoming celebrations, and Parents & Families Weekend.
Plan to attend one of our events. Read up on what's happening in Schreyer. See the impact private support is making in the college.
Have a story idea about alumni achieving professional success? Tell us about it.
Want to suggest an event to bring together Scholar alumni? Let us know.
Plus, you can always check our Facebook page and Twitter account for news and headlines that reflect the college right here, right now.


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Drink lean
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Share on Pinterest Illustration by Brittany England Lean, also known as purple drank, sizzurp, barre, and Texas tea, among other names, is a concoction of cough syrup, soda, hard candy, and, in some cases, alcohol.
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Everybody wants me to stop all this and all that. Lean, also known as purple drank and several other names, is a recreational drug beverage, prepared by combining prescription-grade cough syrup with a soft. DXM cough syrup is available without a prescription, but some states restrict the sale of it to people over the age of The more you take medications with codeine in them, the higher the chance of addiction.
What is lean syrup & what are the side effects of drinking lean?
And misusing codeine over and over can lead to tolerance and addiction. Other names include sizzurp, [3] syrup, [3] drank, [3] barre, [3] purple jelly, [3] wok, [4] Texas tea, [5] dirty Sprite, [6] and Tsikuni. Lean Drug Use in Popular Culture The act of drinking lean has drink lean around since the 90s, and it has become more popular through the hip hop scene. People who drink a lot of lean cough syrup may experience several unpleasant side effects, including: Loss of coordination.
The Los Angeles County Coroner's Office reported that the rapper's death was "due to promethazine-codeine effects and other unestablished factors. Lean is a highly addictive drug that people drink to get high.
It is also a bit of a sedative —employed partly to keep people from drinking too much of the stuff. According to the U. According to TMZ, he had been suffering from liver and kidney problems, which were believed to be the result of his addiction. Unfortunately, some of those side effects could be life-threatening.
Dangers Of Lean The Codeine in prescription cough syrup makes it very addictive. George Fallieras on the hazards of the concoction. Do you or someone you know need help with detoxing from Drugs or Alcohol? Regular use causes a person dribk suffer from constipation, tooth decay, weight gain, and urinary tract infections.
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What is this sizzurp; this addictive concoction that has become a dangerous trend, and helped land aspiring hip hop producer Harisson Garcia behind bars for 30 years? Integrated and Holistic Care llean Treat Lean Drink Addiction When individuals abuse Lean for a long period of time, they may find it hard to stop using on their own.
Other variations of purple drank involve a combination of codeine tablets added to cough syrup and soda. Unfortunately, this only le to an endless cycle of abuse that may require inpatient rehab before individuals achieve long-lasting recovery.
Users make lean by dtink codeine cough syrup or other cough. Drug Enforcement Administration DEAprescription cough syrups containing a small amount of narcotics, such as promethazine with codeine, are classified as Schedule 5 drugs with a low potential for abuse when used as directed. A second drug in the cough syrup, known as promethazine, is used as an antihistamine and commonly used to treat motion sickness and nausea.
Lean drink addiction treatment
Frink with most CNS depressants, mixing with alcohol greatly increases the risk of respiratory failure and other complications. This is a very common cough syrup that, when taken in appropriately prescribed quantities, is quite safe. Please contact is as soon as possible to get the help that is needed. Bow Wow recently opened up about almost dying as a result of his addiction to lean. Although the mixture varies, lean typically consists of cough medicine, soda pop like Mountain Dew or Sprite, and hard candy such as Jolly Ranchers.
What Cough Syrup is used for Lean? However, Purple Drank can lead rdink disastrous health problems that could also lead to death. What Is Lean? However, the cough syrups are highly habit-forming if misused.
While some people may enjoy the euphoric effect of lean, it can also produce other less than desirable, and even downright dangerous, len in high doses, including:. Cough syrups containing codeine fall into the drihk of misuse category since Actavis — considered to be the best of codeine cough syrups by lean users — was taken off the market due to its popularized misuse. Yes and no. Add in any other drugs that might enter the mix drink lean you have a very dangerous cocktail that has left many fighting for their health, and others dead.
Share on Pinterest Illustration by Brittany England Lean, also known as purple drank, sizzurp, barre, and Texas tea, among other names, is a concoction of cough syrup, soda, hard candy, and, in some cases, alcohol. The officers found a Dr Pepper bottle in a holder next to two Styrofoam cups containing soda and ice. Fallieras stated that in its intended usage, "The codeine in the medicine serves as a drink lean reliever and also suppresses coughing.
Your central nervous system begins to rely on codeine to block pain and slow down the way your nervous system communicates with the rest of your body.
This phenomenon is often appealing to first-time users. Commonly known as purple drank, the side effects of lean cough syrup are dangerous and can impact your health and wellbeing.
The amount of each ingredient varies. Many people experience physical withdrawal symptoms after using codeine, even those who are not addicted to lean or codeine in a psychological way.
The officers said the cups and the bottle all emitted "strong odors of codeine" [31] even though the codeine is odorless according to National Institutes of Health. Since lean uses codeine drugs to create the feeling of a high, it has a major effect on your nervous system.
Lean (drug)
Russell was booked into city jail and released soon afterwards after making his bail. However, Pimp C had a history of sleep apneaa condition that causes one to stop breathing for short periods during sleep.
Lea distribution or manufacturing of it without a is illegal. Ronald Peters, Jr. Even first-time users may experience unpleasant side effects such as nausea, blurred vision, dizziness, and memory issues. Usually, lean is made from cough syrup containing promethazine with codeine, a medicine prescribed by doctors to treat cold or allergy symptoms such as cough, runny nose, and sneezing. Although the withdrawal process can be uncomfortable, comprehensive care can make clients feel at ease.
Artists like Justin Bieber, Bow Wow, and the late Mac Miller have spoken laen about drinking lean as well as its addictive nature. Later when wine coolers came onto the market, they substituted for beer. Users make lean by combining codeine cough syrup or other cough and cold medicine, soda, candy, and occasionally alcohol.
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Issues & Trends>Food Safety
New Food Safety Tools
The Safe Quality Food Institute (SQFI), a subsidiary of Food Marketing Institute, is rolling out several technology-based changes to its food safety auditing program this year. Last week it unveiled a new version of its website at www.sqfi.com. The website is designed to provide more detailed information to suppliers, retailers and food safety certification companies working under
Michael Garry 1 | Feb 23, 2009
ARLINGTON, Va. — The Safe Quality Food Institute (SQFI), a subsidiary of Food Marketing Institute here, is rolling out several technology-based changes to its food safety auditing program this year.
Last week it unveiled a new version of its website at www.sqfi.com. The website is designed to provide more detailed information to suppliers, retailers and food safety certification companies working under SQFI's food safety guidelines.
"It offers a simple way to find information," said Jill Hollingsworth-Reed, group vice president, food safety, SQFI. Suppliers, for example, can search on the website for an auditing certification body that is experienced with its product line, and schedule an audit.
Retailers, which have free access to the website's functionality, can use it to search for SQFI-certified suppliers by product, country and other criteria. Beginning in June, retailers will also be able to access detailed audit information, including specific audit scores, with permission from audited suppliers. The information will be stored in a database hosted by Agentrics, Chicago.
On the new website, food safety auditors are able to download a free copy of Quickfire software, from U.K.-based Muddy Boots Software, which enables them to enter detailed food safety information into their laptops at audit sites. The software allows auditors to send results electronically to a certification body, as well as communicate with a supplier being audited. All subsequent changes in the audit can be tracked electronically.
In addition, the software provides auditors with guidelines on how to interpret food safety conditions and determine the severity of a problem. "It hopefully takes out some of the subjectivity," said Hollingsworth-Reed. "We're hoping to have a lot more consistency in scoring and the interpretation of the standard."
John Hanlin, vice president of food safety for Supervalu, Minneapolis, said it's important that the auditors all use the same measurements and standards in assessing the food safety procedures of food manufacturing and processing plants.
FDA update on romaine lettuce links E. coli outbreaks to California growers
Does a growing number of labels on natural foods lead to certification fatigue?
Another big recall for romaine lettuce
Ex-FDA chief revisits efforts to modernize food labeling


Statement of Responsibility words by Ned. Moray ; music by Malvin M. Franklin.
Publisher New Zealand Building, Broadway & 37th St., New York: F.B. Haviland Pub. Co.
Note Illustrated title page: green/white/orange; drawing of a man and a woman talking together on a crowded street and in a restaurant / Pfeiffer; Advertisement, illustrated title page, and excerpts for A girlie was just made to love on unnumbered page, with photographs of Little Belle Brandon, Josephine Knoll, Dorothy Golden, and Marie (Dixie) Warfield; Staff notation.
Subject - Library of Congress Songs with piano.; Popular music - United States - 1911-1920.; Waltzes.; Country life - Songs and music.; Gossip - Songs and music.; Brandon, Belle - Portraits.; Knoll, Josephine - Portraits.; Golden, Dorothy - Portraits.; Warfield, Marie - Portraits.


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Justia US Law US Regulations Department of Commerce National Institute of Standards and Technology 2020 October
National Institute of Standards and Technology October 2020 – Federal Register Recent Federal Regulation Documents
National Cybersecurity Center of Excellence (NCCoE) Zero Trust Cybersecurity: Implementing a Zero Trust Architecture
Document Number: 2020-23292
Type: Notice
Agency: Department of Commerce, National Institute of Standards and Technology
The National Institute of Standards and Technology (NIST) invites organizations to provide products and technical expertise to support and demonstrate security platforms for the Zero Trust Cybersecurity: Implementing a Zero Trust Architecture project. This notice is the initial step for the National Cybersecurity Center of Excellence (NCCoE) in collaborating with technology companies to address cybersecurity challenges identified under the Zero Trust Cybersecurity: Implementing a Zero Trust Architecture project. Participation in the building block is open to all interested organizations.
https://regulations.justia.com/regulations/fedreg/2020/10/21/2020-23292.html
Judges Panel of the Malcolm Baldrige National Quality Award; Meeting
The Judges Panel of the Malcolm Baldrige National Quality Award (Judges Panel) will meet in closed session Monday, November 9, 2020 through Friday, November 13, 2020, from 10:00 a.m. until 5:00 p.m. Eastern Time each day. The purpose of this meeting is to review recommendations from site visits and recommend 2020 Malcolm Baldrige National Quality Award (Award) recipients. The meeting is closed to the public in order to protect the proprietary data to be examined and discussed at the meeting.
Flow Cytometry Standards Consortium
The National Institute of Standards and Technology (NIST), an agency of the United States Department of Commerce, in support of efforts to develop standards for regenerative medicine and advanced therapies, is establishing the Flow Cytometry Standards Consortium (``Consortium''). The Consortium will bring together stakeholders to identify and address measurement and standards needs related to flow cytometry used in the characterization and testing of cell and gene therapies. The Consortium efforts are intended to develop measurement solutions and standards to improve measurement confidence, establish measurement traceability, and enable comparability in flow cytometry measurements. Participation fees will be at least $25,000 annually or in-kind contributions of equivalent value. Participants will be required to sign a Cooperative Research and Development Agreement (CRADA).
Deprecation of the United States (U.S.) Survey Foot
Agency: Department of Commerce, National Institute of Standards and Technology, National Oceanic and Atmospheric Administration
The National Institute of Standards and Technology (NIST) and the National Geodetic Survey (NGS), National Ocean Service (NOS), National Oceanic and Atmospheric Administration (NOAA), have taken collaborative action to provide national uniformity in the measurement of length. This notice announces the final decision to deprecate use of the ``U.S. survey foot'' on December 31, 2022. Beginning on January 1, 2023, the U.S. survey foot should not be used and will be superseded by the ``international foot'' definition (i.e., 1 foot = 0.3048 meter exactly) in all applications. The international foot is currently used throughout the U.S. for a large majority of applications and is typically referred to as simply the ``foot.'' Over time this terminology will become more prevalent in land surveying and mapping communities. Either the term ``foot'' or ``international foot'' may be used, as required for clarity in technical applications. This notice describes public comments received, along with the plan, resources, training, and other activities provided by NIST and NOAA to assist those affected by this transition.
Establishment of the Civilian Innovation Advisory Board and Call for Nominations
The Secretary of Commerce (Secretary), announces the establishment of the Civilian Innovation Advisory Board (The Board) in accordance with the Federal Advisory Committee Act of 1972 (FACA), as amended, and the Secretary of Commerce (Secretary), a discretionary advisory committee. The Board shall provide independent advice and recommendations to the Secretary of Commerce and, upon request, to the Administrator of the General Services Administration (GSA) on issues relevant to the Federal Government's engagement and support of technological innovation, and the incorporation and adoption of emerging technologies and innovative means to address critical technological challenges facing the Federal Government in its provision of services to the public, within the framework of applicable national policies. The National Institute of Standards and Technology (NIST or Institute) through the Department of Commerce (DoC) invites and requests nominations of individuals for appointment to the Board. NIST will consider nominations received in response to this notice for appointment to the Board, in addition to nominations already received. Registered Federal lobbyists may not serve on NIST Federal Advisory Committees in an individual capacity.


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10,000 flying hours
April 11, 2019 (by Eric M. White) - Lt. Col. Barry Cupples, known around here as "JR," rolls back his flight suit sleeve, still dripping with water from the hose-down he received upon stepping through the aircrew door a few minutes earlier. His fellow 910th Operations Group members cheer as he reveals a black-inked C-130H Hercules aircraft tattoo on his forearm with "10,000 Hours" emblazoned above it.
Lt. Col. Barry "JR" Cupples, a navigator with the 757th AS, holds a 10,000 hours sign in the flight deck of a C-130H Hercules aircraft for a photo at the exact moment he completed his ten thousandth C-130 flight hour. Cupples was greeted by a crowd of his 757th wingmen after landing at Youngstown ARS. [USAF photo by Eric M. White]
In many ways, this flight was fairly normal—clear blue skies, a tactical route through the Blue Ridge Mountains of Tennessee, the headset-muffled rumble of the Hercules' four turboprop engines—but for Cupples, it was among the most significant he's flown. The navigator, assigned to the 757th Airlift Squadron here, flew his ten thousandth C-130 hour April 5, 2019.
Cupples enlisted in the Air Force Reserve while a senior in high school. He dreamed of becoming a pilot, following in the footsteps of his father, Lt. Col. Barry Cupples Sr., but first needed a college degree. So he enlisted as a loadmaster, responsible for loading and securing cargo and passengers before and during Air Force flights. After basic military training and loadmaster school at Little Rock Air Force Base, Arkansas, Cupples was assigned to his father's home unit, the 328th Airlift Squadron, at Niagara Falls Air Reserve Station. That's where his aviation career began.
Cupples recalls his first flight out of Niagara.
"I remember, because it was a tactical training sortie, and I was flying with a Vietnam era pilot who was very aggressive," said Cupples. "And having just come from the school at Little Rock, I wasn't used to the flying. I remember being in the back thinking that was the first time I was going to get sick, because he was flying very aggressively."
During the next seven years, Cupples accrued approximately 2500 flight hours as a loadmaster on both C-130As and C-130Es, models much older than the C-130Hs flown out of Younstown Air Reserve Station. He was getting ready to graduate from college and planning his next career steps. His dream of becoming a pilot was thwarted when he learned his eyesight wasn't good enough and that it couldn't be waivered. Intent on serving his country from the C-130's flightdeck rather than its cargo area, Cupples changed courses slightly, deciding to become a navigator. Navigators are trained to safely route Air Force aircraft in a variety of conditions, including combat, using maps and charts, GPS, visual landmarks, radar and other tools.
Cupples went to Officer Training School in 1990 and earned his navigator wings in 1992. His career continued as a navigator at Niagara ARS until 2017. A mission change at Niagara saw their aircraft change from C-130s to KC-135s, which don't require navigators. The change left Cupples with a difficult decision. He could remain at Niagara for the few remaining years before his retirement, but he'd have to take a non-flying position. Alternatively, he could relocate to a C-130 unit. He found an Air Reserve Technician (Air Force Reservist that works a full-time civilian job connected to their reserve position) navigator spot here and jumped at the opportunity to pursue his love of aviation until the end of his career.
Lt. Col. Jeff Shaffer is the commander of the 910th Operations Group at Youngstown ARS and also serves as a C-130 navigator.
"There are milestones for aircrew members where you can change out the number above your Air Force Reserve patch, indicating the number of hours you've flown," said Shaffer. "The first is 1000, then 3000, 5000, 7500 and finally 10000."
As Cupples' career has progressed, his flying hours have dwindled some, so achieving 10 thousand hours wasn't really on his radar until last fall. He was averaging a few hundred flight hours a year, but a deployment gave him a significant jump.
"I got 200 hours on a deployment last fall and realized 10 thousand hours might be attainable," said Cupples.
As the number drew nearer, he realized he'd hit the milestone on a paratrooper drop sortie during the April Unit Training Assembly, when the majority of the 910th Airlift Wing's Reserve Citizen Airmen are at Youngstown ARS for training. The paratrooper requestor ended up cancelling, so the aircrew took the opportunity to fly some local training sorties, and Cupples was prepared. He printed a sign that said, "10,000 hours," for a midflight photo opportunity to commemorate the event. His fellow aircrew members on the ground, however, had bigger plans.
Upon landing, Cupples was greeted by a crowd of 910th personnel, several of whom had water-filled fire extinguishers to give him a celebratory hose-down after de-boarding the aircraft, a tradition usually reserved for the final flight of an aviator's career.
"It was far above what I expected," Cupples said, referring to the greeting party. "When I got back I did not expect the reception I got."
The greeting he received is an indicator of the respect he's earned as a master of his craft and that his wingmen know how rare it is to achieve what Cupples has done. The C-130 is a tactical aircraft, meaning its missions are usually short, one to three-hour local flights to deliver cargo or personnel. It's more common for aircrew members who fly strategic airlift aircraft like the C-5 Galaxy or C-17 Globemaster to achieve such a high number of flight hours, as their sorties can often have double digit lengths.
To put it into perspective, if you boarded an aircraft today, April 11, 2019, and started flying, it would take you until the morning of June 1, 2020 to gain 10 thousand hours of flight time. Only a handful of aircrew members from the 910th OG, three or four by some counts, have achieved the milestone.
Getting to such a high number is hard, if not impossible, only flying sorties from a home station. Cupples has gone on multiple deployments which helped bring his number up. He said that has been one of the biggest challenges in his Air Force career.
"For every hour, obviously, it's time away from the family," said Cupples.
Every flight hour also requires two to three hours of mission planning and debriefing, so the time commitment adds up quickly.
Cupples' coworkers and peers speak highly of his record and mission contributions.
"He's a hard worker, always on point, always on task," said Shaffer. "One of our best instructors, great at teaching the young kids."
As Cupples trains the next generation of aircrew members, hard work and a can do attitude are traits he hopes to pass along.
"There's a lot of times along the way people tell you that you can't do it," he said. "Anything's attainable if you work hard enough for it."
Cupples' flying time has given him a mental highlight reel of memorable sorties, but one stands out as particularly impactful. In 2003, he was scheduled to deliver fuel bladders into western Iraq. With little notice, his aircrew was asked to alter their mission. A service member was critically injured and needed emergency airlift out of country for urgent medical care. Getting their fellow service member to safety and seeing him survive his injuries as a result has had a lasting impact on Cupples.
Looking back on his career and the decisions that led him here, Cupples thinks of what it might have been like had he not decided to stick with flying when Niagara switched to KC-135s and said it's likely he would have retired regretting that he got so close to 10 thousand without actually hitting it.
"I'm just grateful to Youngstown for giving me the opportunity to come here and finish my career flying, cause otherwise, I may have ended up in a non-flying position," said Cupples. "It would have been bad for me to retire with 9600 hours, knowing that goal was attainable."
Mastery can be expected after 10 thousand hours of any activity, and Cupples' skill were on full display as the C-130 touched down at Youngstown ARS on April 5.
"I said we'd be back at 1300," said Cupples. "And we hit that right on the minute. It was just a beautiful day."
Courtesy of 910th Airlift Wing Public Affairs
10000hrs
757th AS
910th AW
Lt. Col. Barry "JR" Cupples, a navigator with the 757th AS, shows a new tattoo commemorating his ten thousandth C-130 flight hour following the milestone sortie on April 6, 2019. Cupples was greeted by a crowd of his 757th wingmen upon reaching the milestone. [USAF photo by Eric M. White]
Lt. Col. Barry "JR" Cupples, a navigator assigned to the 757th AS, displays a new tattoo on his forearm after completing his ten thousandth C-130 flight hour on April 6, 2019. Cupples got the tattoo to commemorate reaching the milestone. [USAF photo by SSgt. Jeff Grossi]
A Reserve Citizen Airman assigned to the 757th AS watches a C-130H #89-9104 taxi to its parking spot on April 6, 2019. The C-130's aircrew included Lt. Col. Barry "JR" Cupples, a 757th AS navigator, who completed his ten thousandth C-130 flight hour aboard the aircraft. Cupples was greeted by a crowd of his 757th wingmen upon reaching the milestone. [USAF photo by SSgt. Jeff Grossi]


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Can academics help cities innovate?
Published October 22, 2018	Human Geography , Impact evidence , Innovation and sustainable practice , Planning and Housing Leave a Comment
Tags: Bristol, city leadership, civic university, engaged scholarship, Europe, local governance, policy relevant research
Robin Hambleton
Robin Hambleton, author of Leading the Inclusive City, reports on how Bristol's innovations in city governance are seen abroad and on how academic analysis can contribute to policy-making.
In the summer the City of Bristol was shortlisted for the International Award of European Capital of Innovation 2018. The iCapital award goes, in theory at least, to the city within Europe that is considered by international experts to be the most innovative. The winner of this competition will be announced on 6 November.
The European iCapital award emulates, in many ways, the European Green Capital Award . This international prize, which recognises the important role of local authorities and local stakeholders in improving the environment, has now reached its tenth birthday. Bristol won this accolade in 2015, and the Bristol iCapital bid sought to build on this achievement.
Are these international awards important? In an era of rampant, self-serving, city promotion, or 'city boosterism' as it is known in the USA, it can be argued that these awards might be in danger of rewarding cities with effective marketing departments, rather than substantive achievements.
Moreover, critics argue that international competition between cities can distort local decision-making. They claim that city leaders pursuing these prizes can lose touch with the need to focus on the effective local delivery of vital public services for local communities.
There is force in these arguments. Much depends on the rigour deployed by the organisations making these awards and on the way individual cities approach the bid process, should they choose to compete.
In the case of European iCapital the EU operates a pretty sturdy evaluation process. It requires all applicant cities to submit fairly detailed bids. An independent, international jury assesses these bids against specified criteria. Shortlisted cities are then required to send a team of representatives to Brussels to present their proposal to the jury in person, and the team is then cross-examined on the content of their bid.
I should declare an interest. Ideas set out in my book, Leading the Inclusive City on how to develop place-based leadership, have contributed to the development of the One City Approach to city governance now being implemented in Bristol. These ideas featured quite boldly in the iCapital bid and Marvin Rees, Mayor of Bristol, invited me to join his team presenting the Bristol bid to the jury of evaluators in Brussels last month. This was a nerve-racking but rewarding experience.
This year Bristol was the only UK city to make it into the group of twelve 'finalist' cities. An announcement by the EU last week indicated that Bristol has not made it into the last six cities. This latest news is disappointing for those who worked on the bid.
However, there are, perhaps, three main reasons why participating in respected, international competitions of this kind is a good idea for cities.
First, the process of preparing and delivering a good submission can, in itself, help civic leaders clarify their thinking, improve their ideas and develop their strategies. Second, raising the visibility of your city in national and international circles is now recognised as an important task for modern city leadership. This is not just because a good reputation can attract potential investors and talented people, it can also raise local confidence and self-esteem. Third, some cities actually win these awards, and the funds can be used to enhance the quality of life of those living in the winning cities.
The Bristol iCapital bid places the city in a small group of cities within Europe that are seen, by independent experts, as highly innovative. In my view, to reach the final stage of this international competition reflects well on the city.
But allow me to raise a broader question. Should academics participate in initiatives of this kind? Some scholars will feel that it is inappropriate to become closely associated with specific policy initiatives. They will argue, and it is an intellectually coherent argument, that academics should observe, analyse and reflect, not act in an explicit way as policy advisers.
A contrary view, and one that enlightens the shift to 'engaged scholarship' now visible in many countries is that, while scholars must, of course, retain their independence, scholarship can be improved and advanced by contributing directly to public policy debates and community-based campaigns.
Leading the inclusive city by Robin Hambleton is available with 20% discount on the Policy Press website. Order here for £20.79.
Feature Image from Bristol City Council.
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The first family of Metropolis are on Apokolips and in big trouble. Superman has been dragged into Lex Luthor's scheme to save his skin, pegged as the prophesied saviour of Apokolips. Lois has been co-opted into the Female Furies, where survival depends on remaining in Granny Goodness's bad graces.
And Jon? He's alone in the badlands and feeling hungry. His appetite soon goes.
As an animal lover, Jon can't stand by, even if revealing himself makes him a tiny target for these alien warriors.
Good boy! In reuniting pups and parents, Jon finds his first allies in this terrifying realm.
Superman, meanwhile, is trying to avoid enforced messiah-hood. And resisting the temptation to clobber Lex for getting him into this situation.
Their arguing leaves Superman and Lex open to a sneak attack by Kalibak, one of Darkseid's pesky kids, whose plan to find dear old departed dad involves... fracking in the Fire Pits?
And then who should turn up but Granny and her girls, including a familiar face.
What happens next just continues the goodness this issue has delivered so far - big action and terrific characterisation, ending on a wonderful note. The final image won't surprise anyone who's seen the regular cover, but it's even better in the story context.
Writers Patrick Gleason and Peter J Tomasi are taking us, along with the Kents, on a rollicking rollercoaster ride. They do a tremendous job of laying out the position of the various Apokoliptian factions, from the followers of Adora to the minions of Kalibak, the Female Furies to the Lowlies. The absence of Darkseid - currently in kiddie form on Earth - has left a power vacuum to be filled, and the Superman Family are caught in the middle.
I've read many a tale set on Apokolips, but this is one of the better non-Jack Kirby evocations. Take, for example, Jon's description of the smell of the place.
And it's great to know that despite her history as Darkseid's favourite minion, Granny isn't popular with all his troops. It's also good to see that even on a world as traditionally gloomy as Apokolips, Superman can inspire hope. I also like that he's human enough to almost give away the fact of his family to Lex.
I realise this is Apokolips and people aren't nice, and Jon needs motivation, but I do wish our writers hadn't gone so detailed on the unpleasantness towards the dogs. It's almost a cooking manga at one point. This isn't a comic to read with your supper.
Illustrating the book we have three artists, Travis Moore, Stephen Segovia and Art Thibert. I'm taking it Moore fully illustrates the Superman and Lex scenes, while Segovia's Superboy pages are finished by veteran inker Thibert. If I'm wrong, please correct me!
That angle on Lex and Superman is especially impressive, not every artist could pull it off. And there's some fine texturing in the Superman and Lex story that speaks to the dusty grimness of the world Darkseid made.
As for the Jon story, the emotions are always written on his face, while the giant dogs are somewhere between terrifying and adorable.
All this, plus first rate Kirby Krackle and Lois in a unique Female Furies outfit... someone has serious sewing skills to knock up that S-chest design so speedily. Any suggestions as to a Lashina/Screaming Mimi/Mad Harriet-style name for her?
Kudos, too, to Dinei Ribeiro for sterling colourwork - there's a real vibrancy throughout - and Rob Leigh for his ever-thoughtful lettering... I do like that the gigantic Kalibak gets a larger than usual font.
Gleason and colourist Dean White provide the main cover, and while it's striking, I do wish another moment from the issue had been chosen. There's a Justice League movie variant by Renato Guedes which is mostly very decent, though Gal Gadot's face to hair ratio makes Wonder Woman look deeply weird.
But that's not the book. The book is Clark, Lois and Jon on Apokolips, dealing with every horror thrown at them. And it's terrific from beginning to end.
If memory serves, the parents did find out. Luthor never knew Jon was Superman's kid.
I'm with you. This is a fun story. The internal strife as Apokolips suffers from this power vacuum is interesting on its own. But seeing Superman struggle with being viewed as a Messiah and Lex simply washing his hands of it is the real thought provoking thing for me.
As you say, Lois and Jon's adventures are also a blast. I love Jon loving dogs too much to see them be eaten.
As for Lois' Fury name - how about Apoptosis Lois - scheduled cell death!
Safe to say, that's not a name I could come up with! Nice one.
A long-lost cousin of Larry Lance?


Selling on eBay for $6 + shipping in US only.
Yah know, I added this to my collection back when I joined MFC but I never noticed this was actually Alicia until today. I kinda thought the only one that they were gonna make was for Nanoha Innocent with Fate set that never came to light, so this is actually much cooler than I expected. Alicia doesn't get much love. I'd be even more surprised if they ever started making side characters like Rynith and such.
Selling the entire box for US$ 60. The box has been opened to check what the extra petit is, and lucky this box comes with two Nanoha!
nendoroid petit: mahou shoujo lyrical nanoha the movie 1st?


text:
These Are Some of the Most Dangerous Medications in America [infographic]
Opioids, birth control pills, Zithromax, selective serotonin reuptake inhibitors (SSRIs), and acetaminophen plus alcohol are some of the most dangerous medications in America. Drug-related fatalities are increasing dramatically across the nation, and tens of thousands of Americans lose their lives every year due to drug-related reasons. Some drugs cause severe complications or even death after just a single dose, while others lead to death after prolonged use.
The Most Dangerous Drugs in America
Opioids are a group of prescription drugs used mostly as pain relievers. They include hydrocodone, morphine, codeine, oxycodone, fentanyl, and others. These kinds of drugs are extremely effective in treating severe pain, especially when utilized temporarily. Unfortunately, they are extremely addictive and result in dependence and abuse within no time.
Abuse of prescription opioids can cause a patient to look for stronger drugs, such as heroin and cocaine. This usually happens when the 'high" provided by prescription opioids is no longer sufficient for him or her. Opioids abuse has become a serious health concern in the United States, with around 91 people dying every day in 2015.
These types of drugs prevent pregnancy by ending the ovulation process of a woman. They achieve this by using synthetic versions of hormones progestin and estrogen. By stabilizing the natural hormone levels of the woman, these synthetic hormones keep estrogen from reaching the peak at the middle of the menstruation cycle. Due to the lack of estrogen surge, the pituitary gland is unable to release other hormones responsible for triggering the ovaries to release eggs.
Birth control pills consisting of both estrogen and progestin are called "combination pills," while those containing only progestin are called "minipills." Women who frequently use combination pills are at a higher risk of suffering blood clots, especially pulmonary embolism (PE) and deep vein thrombosis (DVT).
Selective Serotonin Reuptake Inhibitors (SSRIs)
SSRI are often prescribed for patients with various psychological disorders, such as panic disorder, bipolar disorder, eating disorder, anxiety, and depression. Some of the popular SSRIs brands are Lexapro, Prozac, Zoloft, and Paxil. They function by raising serotonin levels to reinstate the chemical balance within the brain. This mechanism of action can, however, cause mood swings that can further exacerbate anxiety and depression.
Although most patients attain positive outcomes with SSRIs, various studies have linked these medications with higher risks of suicidal thoughts and habits among some patients, particularly children and adolescents. In fact, a clinical trial carried out by the FDA revealed that patients who took an SSRI had two times higher rate of suicidal thinking or actions than their counterparts who took a placebo.
Commonly called Zmax or Z-pak, Zithromax is an antibiotic prescribed for a wide array of bacterial infections. When it was introduced around two decades ago, this medication gained immense popularity due to its effectiveness and brief treatment course. In the last few years, however, medical professionals have discovered that the effectiveness of Zithromax has declined because a variety of bacterial infection strains have developed resistance to the medication. Researchers believe Zithromax has become ineffective due to over-prescription.
One study in the Jama Internal Medicine journal shows that strep bacteria cause just 10 percent of all sore throats and only those need antibiotic treatment. Researchers, however, discovered that medical practitioners prescribe antibiotics for 60 percent of all patients with sore throat symptoms. Zithromax is surprisingly prescribed in 15 percent of all those sore throat cases. As a result, these medical practitioners have unreasonably exposed many patients to the serious health risks related to Zithromax side effects like fatal cardiac arrhythmia issues. Zithromax is an FDA-approved drug but that doesn't give it a clean bill of health. An FDA label doesn't mean a pharmaceutical medication is completely safe.
A person who has developed cardiac arrhythmia problems due to the use of Zithromax can recover compensation for his or her prescribed medical injuries. A personal injury lawyer can review the medical records and collect enough evidence to help such a person recover maximum compensation from the negligent physician. Finding an injury lawyer who will work on a contingency basis will ensure the injured party won't pay any legal fees unless he or she wins.
Acetaminophen Plus Alcohol
While acetaminophen is a harmless over-the-counter (OTC) pain reliever, it can cause acute liver damage or failure and even death when combined with alcohol. Acetaminophen plus alcohol forces the liver to work strenuously to break down both substances, which mostly overwhelms the liver.
The alcohol breaks down faster than acetaminophen, leaving behind higher amounts of toxic acetaminophen enzymes inside the body. These toxic enzymes can result in severe liver damage or failure. It is, therefore, advisable for patients taking acetaminophen to avoid consuming alcohol.


The first teaser for next summer's highly-anticipated sequel Jurassic World: Fallen Kingdom has (as the kids say) dropped.
Get excited because the first full trailer for Jurassic World's follow-up will dis(e)rupt what you're doing in the best way imaginable with ground shaking action, adventure, and breathtaking suspense this Thursday. Stay tuned to Jimmy's Daily Planet to watch the forthcoming trailer later this week.
It's no secret that the movie industry is constantly reforming the way it interacts with audiences to introduce and persuade people to see particular films. For many moviegoers, however, the content of the film (the story, actors and actresses, director, writer, etc.) is enough to spark interest. Still, this reality doesn't prevent movie studios (large and small) from adapting to the modern online, social media and viral marketing phenomenon. This includes teaser trailers, movie poster reveals, multiple subsequent trailers (perhaps too many?) and rare insights (clips and cast interviews) for an upcoming movie at special events, like Comic-Con.
And movie fans are typically very thankful for these efforts, especially when done with added degrees of creativity.
Enter Jimmy Kimmel, Marvel Studios and Chris from Lake Stevens, WA for a brand new look at a small budget independent film.
They like to have fun…and they're pretty good at this "entertainment" thing.
The Future Guardians of the Box Office?
Guardians of the Galaxy Vol. 2 recently debuted its teaser trailer and it's safe to say that fans have reacted quite positively to this sneak peak.
With this kind of surreal fanfare for the new sequel to Guardians of the Galaxy, perhaps the best thing to do is watch this online and pop culture phenomenon.
This superhero movie (and Baby Groot) looks like a hoot.


David Mihm has just posted about some refinements that have been made to the US version of GetListed.
I can't comment too much on this as it's "US Only" at the moment. As the post points out, work is being done on the UK and Canada versions, so they are currently offline.
Anyway, look forward to hearing from you guys how the improvements have helped.
Thanks for posting Nick. Looks like a good update!
It's a nice update, indeed. The only trouble I've seen so far, based on a few scans, is that the counter for reviews is wayyy off.
To be honest, I've noticed the numerous errors with the UK version, so I'm quite glad that its been taken off for some maintenance.
I checked the UK version out a couple of times but the info was so suspect I stopped bothering with it - very frustrating. Hope they will sort things out in the revamp.


In an effort to reduce Marquette's environmental footprint, Marquette Student Government and Sodexo, Inc. implemented a reusable to-go container system in the Alumni Memorial Union, Mashuda and Schroeder dining halls.
The idea for the reusable containers, called Ozzi, has been in the works for three years, said Kevin Gilligan, general manager of University Dining Services. As Marquette works to be more sustainable, Sodexo wants to be more sustainable as well.
"Marquette Place alone was going through 75,000 containers a semester that were going straight to the landfill," Gilligan said. Although the regular containers are biodegradable, they are just as harmful as styrofoam when not processed correctly.
According to MUSG president Kyle Whelton, prior ideas for utilizing reusable containers did not meet standards over the last couple of years. Gilligan presented the opportunity to work with Ozzi to the AMU Advisory Board and the Dining Advisory Board. The Ozzi system fit perfectly into what Sodexo was trying to do with sustainability.
MUSG allocated almost $45,000 from the reserve fund to purchase two Ozzi machines to supplement the single machine purchased by the university. Sodexo funded the containers.
The reusable containers were provided to every student on a meal plan and living in the residence halls.
To use the containers, students can take them to any Ozzi machine to be cleaned. There are two in the AMU and one in Schroeder dining hall. Students deposit the container into the machine and receive an Ozzi token. The token can be taken to Marquette Place, Mashuda dining hall or Schroeder dining hall. If a student asks for a to-go box they are given the option of paper or plastic, as well as disposable or reusable.
Gilligan said the tokens are used to allow students to not be charged for the reusable containers if they plan to recycle them.
"If a student has the reusable container, the cashier automatically rings in the charge for the container at the time of checkout, but when the student presents the token, the charge for the container comes off," Gilligan said. When students finish their meal, they can bring the container back to the machine and the process repeats.
Upperclassmen who are not on a meal plan have a chance to be a part of the Ozzi system. Over the next couple of weeks Gilligan, Whelton and Rick Arcuri, director of business operations and auxiliary services for Student Affairs, will be around campus handing out tokens to anyone interested. Receiving a token admits a student to the program.
Although the reusable containers are the focus of the Ozzi system, paper containers will still be available. MUSG decided, however, that after Sept. 8 there will be a 50- cent charge for the paper containers. This charge helps fund the program to keep it going in the future.
If students not in the residence halls need to buy a container, it costs a one-time fee of five dollars. If a container breaks, it is replaced for free, but if it gets lost or thrown away it will be five dollars to replace.
"So far student reactions have been incredibly positive to the Ozzi initiative," Arcuri said.
Whelton said the Ozzi initiative will take time, but Marquette is taking steps to become a more efficient campus.
There will also be a video coming soon provided by MUSG showing how to use the Ozzi system.


This guide will walk you through the process of replacing the motherboard, to get your tablet working again. This replacement requires soldering skills. Learn more about soldering, here.
Remove the two pieces of tape securing the ribbon cables to the motherboard.
Remove the 3 screws at the top of the motherboard.
Using a plastic prying tool, lift open the latch that secures the ribbon cable next to the speaker.
Pull the ribbon cable out of its connector on the motherboard.
Use a plastic prying tool to disconnect the other ribbon cable from the motherboard. This cable belongs to the device's cameras.
Disconnect the large ribbon cable from the motherboard. Do this by unlocking the tabs on each side of the connector.
Snip the two sets of wires that are attached to the motherboard. Cut the wires as close to the board as possible. This will leave plenty of length to reattach the wires to the new board.
Skip this step if you are only removing the motherboard to replace the screen.


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Q: Batch file, loop on folder seems to freeze I need to delete with a batch a list of directories (and subdir) which name starts with a number.
My tree is something like that:
|- root
    |--event=aaa
        |--photo
            |--123
                |--44
                    |--23
                |--89
        |--otherdir
    |--event=bbb
        |--photo
            |--432
                |--67
                    |--12
                |--32
        |--otherdir

I found this working example: http://www.dostips.com/forum/viewtopic.php?f=3&t=1496
And this is what I wrote
@ECHO OFF
SET path=\\mypath
SET dir=\parentDir\

:: loop on event=* folders
FOR /D /R %path%%dir% %%K IN ("*event*") DO (
    :: if an event contains photos ..
    IF EXIST %%K\photo (
        ECHO %%K

        :: loop on dir inside photo folder with a numeric name
        PUSHD %%K\photo ||goto :eof
        FOR /f "delims=" %%a IN ('dir /ad /b /s ^|findstr /rc:"\\[0-9]"') DO (
            IF EXIST %%~a (
                RD /s /q "%%~a"
            )
        )
        POPD
    ) ELSE (
        ECHO.%%K /photo does not exists
    )
)
ECHO.completed
PAUSE

the only problem I found is that the execution seems to freeze when the last /event=xxx folder, and takes quite a long time to ECHO the last line ("completed"). I don't understand why .. any ideas?
Many thanks

A: You can try this.  It will delete every folder under the *event* folders that have only numbers in the names.
Currently it will pause on each main folder after merely listing the set of subdirectories that would be deleted, and is not destructive.  If the commands look right then remove the echo and the pause to activate the RD command to actually delete the folders.
@echo off
for /f "delims=" %%a in (' dir "*event*" /ad /b ') do (
  for /f "delims=" %%b in (' dir "%%a" /ad /b /s ') do (
       for /f "delims=0123456789" %%c in ("A%%~nxb") do (
        if "%%c"=="A" if exist "%%b\" echo rd /s/q "%%b"
     )
  )
  pause
)

A: @ECHO OFF
SETLOCAL
SET mypath=.
SET dir=\parentdir\

FOR /f "delims=" %%i IN (
 ' dir /ad /s /b "%mypath%%dir%" ^|findstr /r "\\.*event.*\\photo\\[0-9].*" ' ) DO (
 IF EXIST "%%i" ECHO RD /s /q %%i
)

This should do as you ask - with some cautions.
I've changed the variable names. PATH is not a good name to use because PATH is the sequence of directories which the OS searches for an executable.
I've also changed the value to suit my system.
I've added an ECHO keyword rather than arbitrarily deleting the target directories - just in case of a typo - gives you a chance at verifying first. This ECHO would need to be removed to activate the delete functionality.
The findstr regular expression is \ (which requires an extra \ as an escape) any number of any characters, event, any number of any characters, \photo\, a digit then any number of any characters.
Please also note that the "broken label" form of comment (::) should not be used within a loop. Whereas it (and labels) works within a loop in W7 (and presumably later,) it terminates the loop in some earlier Windows editions, whereas REM works for all editions.