Transport Minister Simon Bridges says work is ramping up on a $60 million investment programme to upgrade the alternate state highway route between Picton and Christchurch while the reconstruction of State Highway 1 through Kaikoura is underway.
"The Government's investment in the alternate route includes a range of road improvements to make the route safer and more resilient," Mr Bridges says.
Economic Development Minister Simon Bridges and Sport and Recreation Minister Jonathan Coleman today announced a $5.5 million investment into two major golfing events.
Through the Major Events Development Fund $2.7 million will be committed to New Zealand Golf to support the hosting of the McKayson New Zealand Women's Open from 2017 to 2019.
$2.8 million will also be invested over three years in support the annual ISPS Handa NZ Golf Open. The 2017 tournament gets underway in Queenstown tomorrow.
Transport Minister Simon Bridges has announced that the NZ Transport Agency is working to ensure significant improvements to a section of State Highway 1 between Whangarei and Port Marsden Highway are completed as quickly as possible, with construction planned to start by 2019.
Transport Minister Simon Bridges says transport infrastructure continues to be a priority in Northland as the region marked the start of two new transport projects and celebrated the completion of more today.
The Minister turned the sod for Whāngārei's newest Urban Cycleway, the $6.6m Kamo Shared Path, a 6km path that will connect areas north of the city with the Whāngārei CBD, Tai Tokerau Auckland University Campus and links to key recreational areas such as Kensington Park.
Transport Minister Simon Bridges says new barriers along a section of State Highway 1 in the Auckland suburb of Ellerslie will help to reduce noise for those living near the motorway.
The NZ Transport Agency plans to begin construction of the sound barriers on its land adjacent to the motorway by the middle of this year.
Economic Development Minister Simon Bridges and Arts, Culture and Heritage Minister Maggie Barry today announced funding will be made available for tourism infrastructure and cultural events as part of the Tairawhiti Economic Action Plan.
Transport Minister Simon Bridges has announced that the Government will work with local stakeholders to identify and prioritise transport initiatives to help boost economic growth in Gisborne.
The announcement was made at the release of the Tairāwhiti Economic Action Plan in Gisborne today.
"The Integrated Transport Priority Plan will provide an opportunity for the region to help shape the transport network and find solutions to meet the needs of local customers, businesses, such as the forestry sector, and tourists," says Mr Bridges.
Economic Development Minister Simon Bridges, Associate Primary Industries Minister Louise Upston and other Ministers are in Gisborne today for the release of the Tairāwhiti Economic Action Plan, highlighting the Government's support for the region.
The plan has been developed by Tairāwhiti people for the community and represents a shared investment in the future. The plan's development was led by the Tairāwhiti Action Plan Governance Group and is supported through the Government's Regional Growth Programme.
Minister for Economic Development Simon Bridges and Social Development Minister Anne Tolley have today announced a final extension to the support package for businesses affected by the Kaikōura earthquake.
The Government approved $17.5 million dollars to support businesses in Kaikōura, Hurunui, Marlborough and Wellington post-earthquake. To date businesses have accessed almost $14.9 million of that fund.
Crankworx, the world's biggest mountain bike festival, will be held in Rotorua from 25 March to 2 April this year. It has previously been hosted in Whistler and the French Alps.
Transport Minister Simon Bridges today opened a new section of State Highway 3 north of Normanby that will improve both capacity and safety on a critically important route for the Taranaki region.
The $17.6 million project was identified as a priority in the 2012-2015 Regional Land Transport Programme for Taranaki.
It was also included in the Government's Accelerated Regional Roading Package which makes significant funding available to a number of regionally important State Highway projects.


On this project in Somers, DCS installed cladding on the entire building but here we are featuring the garage door as well as a small portion of the cladding that covers the rest of the house. These panels are anthracite aluminium in varying sizes, installed using a standing seam profile, and meet here in this photograph to create a seamless mitred corner detail. The garage door consists of aluminium panels painted in Naturel Antique Copper and were installed using an interlocking profile. The garage door is seamlessly integrated into the surrounding wall, making it difficult to see where it starts and ends. Both types of panels are aluminium, chosen specifically for this house's location as it sits on the top of a cliff overlooking Westernport Bay and these aluminium panels are durable, able to withstand the salt and harsh environment of this cliff site.


text:
Label: RANITIDINE solution
NDC Code(s): 65162-664-90
Packager: Amneal Pharmaceuticals LLC
The active ingredient in Ranitidine Oral Solution, USP is ranitidine hydrochloride (HCl), USP, a histamine H2-receptor antagonist. Chemically it is N[2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethyl]-N′-methyl-2-nitro-1,1-ethenediamine, HCl. It has the following structure:
The empirical formula is C13H22N4O3S•HCl, representing a molecular weight of 350.87.
Ranitidine HCl, USP is a white to pale yellow, granular substance that is soluble in water. It has a slightly bitter taste and sulfurlike odor.
Each 1 mL of Ranitidine Oral Solution, USP contains 16.8 mg of ranitidine HCl, USP equivalent to 15 mg of ranitidine. Ranitidine Oral Solution, USP also contains the inactive ingredients butylparaben, dibasic sodium phosphate, hypromellose, monobasic sodium phosphate, natural peppermint extract, propylene glycol, propylparaben, purified water, saccharin sodium, sodium chloride, and sorbitol solution.
Ranitidine hydrochloride is a competitive, reversible inhibitor of the action of histamine at the histamine H2-receptors, including receptors on the gastric cells. Ranitidine hydrochloride does not lower serum Ca++ in hypercalcemic states. Ranitidine hydrochloride is not an anticholinergic agent.
Absorption: Ranitidine hydrochloride is 50% absorbed after oral administration, compared to an intravenous (IV) injection with mean peak levels of 440 to 545 ng/mL occurring 2 to 3 hours after a 150-mg dose. The oral solution formulation is bioequivalent to the tablets. Absorption is not significantly impaired by the administration of food or antacids. Propantheline slightly delays and increases peak blood levels of ranitidine, probably by delaying gastric emptying and transit time. In one study, simultaneous administration of high-potency antacid (150 mmol) in fasting subjects has been reported to decrease the absorption of ranitidine hydrochloride.
Distribution: The volume of distribution is about 1.4 L/kg. Serum protein binding averages 15%.
Metabolism: In humans, the N-oxide is the principal metabolite in the urine; however, this amounts to <4% of the dose. Other metabolites are the S-oxide (1%) and the desmethyl ranitidine (1%). The remainder of the administered dose is found in the stool. Studies in patients with hepatic dysfunction (compensated cirrhosis) indicate that there are minor, but clinically insignificant, alterations in ranitidine half-life, distribution, clearance, and bioavailability.
Excretion: The principal route of excretion is the urine, with approximately 30% of the orally administered dose collected in the urine as unchanged drug in 24 hours. Renal clearance is about 410 mL/min, indicating active tubular excretion. The elimination half-life is 2.5 to 3 hours. Four patients with clinically significant renal function impairment (creatinine clearance 25 to 35 mL/min) administered 50 mg of ranitidine intravenously had an average plasma half-life of 4.8 hours, a ranitidine clearance of 29 mL/min, and a volume of distribution of 1.76 L/kg. In general, these parameters appear to be altered in proportion to creatinine clearance (see DOSAGE AND ADMINISTRATION).
Geriatrics:
The plasma half-life is prolonged and total clearance is reduced in the elderly population due to a decrease in renal function. The elimination half-life is 3 to 4 hours. Peak levels average 526 ng/mL following a 150-mg twice-daily dose and occur in about 3 hours (see PRECAUTIONS: Geriatric Use and DOSAGE AND ADMINISTRATION: Dosage Adjustment for Patients With Impaired Renal Function).
Pediatrics:
There are no significant differences in the pharmacokinetic parameter values for ranitidine in pediatric patients (from 1 month up to 16 years of age) and healthy adults when correction is made for body weight. The average bioavailability of ranitidine given orally to pediatric patients is 48% which is comparable to the bioavailability of ranitidine in the adult population. All other pharmacokinetic parameter values (t1/2, Vd, and CL) are similar to those observed with intravenous ranitidine use in pediatric patients. Estimates of Cmax and Tmax are displayed in Table 1.
Table 1. Ranitidine Pharmacokinetics in Pediatric
Patients Following Oral Dosing
(age) n Dosage Form
(dose) Cmax
(ng/mL) Tmax
(hours)
Gastric or duodenal ulcer(3.5 to 16 years) 12 Tablets(1 to 2 mg/kg) 54 to 492 2
Otherwise healthy requiring Ranitidine Oral Solution(0.7 to 14 years, Single dose) 10 Oral Solution(2 mg/kg) 244 1.61
Otherwise healthy requiring Ranitidine Oral Solution(0.7 to 14 years, Multiple dose) 10 Oral Solution(2 mg/kg) 320 1.66
Plasma clearance measured in 2 neonatal patients (less than 1 month of age) was considerably lower (3 mL/min/kg) than children or adults and is likely due to reduced renal function observed in this population (see PRECAUTIONS: Pediatric Use and DOSAGE AND ADMINISTRATION: Pediatric Use).
Serum concentrations necessary to inhibit 50% of stimulated gastric acid secretion are estimated to be 36 to 94 ng/mL. Following a single oral dose of 150 mg, serum concentrations of ranitidine are in this range up to 12 hours. However, blood levels bear no consistent relationship to dose or degree of acid inhibition.
Antisecretory Activity:1. Effects on Acid Secretion: Ranitidine Oral Solution inhibits both daytime and nocturnal basal gastric acid secretions as well as gastric acid secretion stimulated by food, betazole, and pentagastrin, as shown in Table 2.
Table 2. Effect of Ranitidine Oral Solution on Gastric Acid Secretion
Time After Dose, hours % Inhibition of Gastric Acid Output by Dose, mg
75 to 80 100 150 200
Basal Up to 4 99 95
Nocturnal Up to 13 95 96 92
Betazole Up to 3 97 99
Pentagastrin Up to 5 58 72 72 80
Meal Up to 3 73 79 95
Basal Up to 4 75 to 80 100 150 200
It appears that basal-, nocturnal-, and betazole-stimulated secretions are most sensitive to inhibition by Ranitidine Oral Solution, responding almost completely to doses of 100 mg or less, while pentagastrin- and food-stimulated secretions are more difficult to suppress.
2. Effects on Other Gastrointestinal Secretions:
Pepsin: Ranitidine Oral Solution does not affect pepsin secretion. Total pepsin output is reduced in proportion to the decrease in volume of gastric juice.
Intrinsic Factor: Ranitidine Oral Solution has no significant effect on pentagastrin-stimulated intrinsic factor secretion.
Serum Gastrin: Ranitidine Oral Solution has little or no effect on fasting or postprandial serum gastrin.
Other Pharmacologic Actions:
Gastric bacterial flora—increase in nitrate-reducing organisms, significance not known.
Prolactin levels—no effect in recommended oral or intravenous (IV) dosage, but small, transient, dose-related increases in serum prolactin have been reported after IV bolus injections of 100 mg or more.
Other pituitary hormones—no effect on serum gonadotropins, TSH, or GH. Possible impairment of vasopressin release.
No change in cortisol, aldosterone, androgen, or estrogen levels.
No antiandrogenic action.
No effect on count, motility, or morphology of sperm.
Pediatrics: Oral doses of 6 to 10 mg/kg/day in 2 or 3 divided doses maintain gastric pH>4 throughout most of the dosing interval.
Clinical Trials:Active Duodenal Ulcer:
In a multicenter, double-blind, controlled, US study of endoscopically diagnosed duodenal ulcers, earlier healing was seen in the patients treated with Ranitidine Oral Solution as shown in Table 3.
Table 3. Duodenal Ulcer Patient Healing Rates
Ranitidine Oral Solution* Placebo*
Number Entered Healed/ Evaluable Number Entered Healed/ Evaluable
Outpatients 195 69/182(38%)† 188 31/164(19%)
Week 4 137/187(73%)† 76/168(45%)
*All patients were permitted antacids as needed for relief of pain.
†P<0.0001.
In these studies, patients treated with Ranitidine Oral Solution reported a reduction in both daytime and nocturnal pain, and they also consumed less antacid than the placebo-treated patients.
Table 4. Mean Daily Doses of Antacid
Ulcer Healed Ulcer Not Healed
Ranitidine Oral Solution 0.06 0.71
Placebo 0.71 1.43
Foreign studies have shown that patients heal equally well with 150 mg twice daily and 300 mg at bedtime (85% versus 84%, respectively) during a usual 4-week course of therapy. If patients require extended therapy of 8 weeks, the healing rate may be higher for 150 mg twice daily as compared to 300 mg at bedtime (92% versus 87%, respectively).
Studies have been limited to short-term treatment of acute duodenal ulcer. Patients whose ulcers healed during therapy had recurrences of ulcers at the usual rates.
Maintenance Therapy in Duodenal Ulcer: Ranitidine has been found to be effective as maintenance therapy for patients following healing of acute duodenal ulcers. In 2 independent, double-blind, multicenter, controlled trials, the number of duodenal ulcers observed was significantly less in patients treated with Ranitidine Oral Solution (150 mg at bedtime) than in patients treated with placebo over a 12-month period.
Table 5. Duodenal Ulcer Prevalence
Double-Blind, Multicenter, Placebo-Controlled Trials
Multicenter Trial Drug Duodenal Ulcer Prevalence No. of Patients
0 to 4Months 0 to 8Months 0 to 12Months
USA RAN 20%* 24%* 35%* 138
PLC 44% 54% 59% 139
Foreign RAN 12%* 21%* 28%* 174
% = Life table estimate.
* = P<0.05 (Ranitidine Oral Solution versus comparator).
RAN = ranitidine (Ranitidine Oral Solution).
PLC = placebo.
As with other H2-antagonists, the factors responsible for the significant reduction in the prevalence of duodenal ulcers include prevention of recurrence of ulcers, more rapid healing of ulcers that may occur during maintenance therapy, or both.
Gastric Ulcer: In a multicenter, double-blind, controlled, US study of endoscopically diagnosed gastric ulcers, earlier healing was seen in the patients treated with Ranitidine Oral Solution as shown in Table 6.
Table 6. Gastric Ulcer Patient Healing Rates
Outpatients 92 16/83(19%) 94 10/83(12%)
Week 6 50/73(68%)† 35/69(51%)
*All patients were permitted p.r.n. antacids for relief of pain.
†P = 0.009.
In this multicenter trial, significantly more patients treated with Ranitidine Oral Solution became pain free during therapy.
Maintenance of Healing of Gastric Ulcers: In 2 multicenter, double-blind, randomized, placebo-controlled, 12-month trials conducted in patients whose gastric ulcers had been previously healed, Ranitidine Oral Solution 150 mg at bedtime was significantly more effective than placebo in maintaining healing of gastric ulcers.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): Ranitidine hydrochloride inhibits gastric acid secretion and reduces occurrence of diarrhea, anorexia, and pain in patients with pathological hypersecretion associated with Zollinger-Ellison syndrome, systemic mastocytosis, and other pathological hypersecretory conditions (e.g., postoperative, "short-gut" syndrome, idiopathic). Use of Ranitidine Oral Solution was followed by healing of ulcers in 8 of 19 (42%) patients who were intractable to previous therapy.
Gastroesophageal Reflux Disease (GERD): In 2 multicenter, double-blind, placebo-controlled, 6-week trials performed in the United States and Europe, Ranitidine Oral Solution 150 mg twice daily was more effective than placebo for the relief of heartburn and other symptoms associated with GERD. Ranitidine-treated patients consumed significantly less antacid than did placebo-treated patients.
The US trial indicated that Ranitidine Oral Solution 150 mg twice daily significantly reduced the frequency of heartburn attacks and severity of heartburn pain within 1 to 2 weeks after starting therapy. The improvement was maintained throughout the 6-week trial period. Moreover, patient response rates demonstrated that the effect on heartburn extends through both the day and night time periods.
In 2 additional US multicenter, double-blind, placebo-controlled, 2-week trials, Ranitidine Oral Solution 150 mg twice daily was shown to provide relief of heartburn pain within 24 hours of initiating therapy and a reduction in the frequency of severity of heartburn.
Erosive Esophagitis: In 2 multicenter, double-blind, randomized, placebo-controlled, 12-week trials performed in the United States, Ranitidine Oral Solution 150 mg 4 times daily was significantly more effective than placebo in healing endoscopically diagnosed erosive esophagitis and in relieving associated heartburn. The erosive esophagitis healing rates were as follows:
Table 7. Erosive Esophagitis Patient Healing Rates
Healed/Evaluable
Placebo*
n = 229 Ranitidine Oral Solution
150 mg 4 times daily*
Week 4 43/198 (22%) 96/206 (47%)†
Week 8 63/176 (36%) 142/200 (71%)†
Week 12 92/159 (58%) 162/192 (84%)†
†P<0.001 versus placebo.
No additional benefit in healing of esophagitis or in relief of heartburn was seen with a ranitidine dose of 300 mg 4 times daily.
Maintenance of Healing of Erosive Esophagitis: In 2 multicenter, double-blind, randomized, placebo-controlled, 48-week trials conducted in patients whose erosive esophagitis had been previously healed, Ranitidine Oral Solution 150 mg twice daily was significantly more effective than placebo in maintaining healing of erosive esophagitis.
Ranitidine Oral Solution is indicated in:
Short-term treatment of active duodenal ulcer. Most patients heal within 4 weeks. Studies available to date have not assessed the safety of ranitidine in uncomplicated duodenal ulcer for periods of more than 8 weeks.
Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers. No placebo-controlled comparative studies have been carried out for periods of longer than 1 year.
The treatment of pathological hypersecretory conditions (e.g., Zollinger-Ellison syndrome and systemic mastocytosis).
Short-term treatment of active, benign gastric ulcer. Most patients heal within 6 weeks and the usefulness of further treatment has not been demonstrated. Studies available to date have not assessed the safety of ranitidine in uncomplicated, benign gastric ulcer for periods of more than 6 weeks.
Maintenance therapy for gastric ulcer patients at reduced dosage after healing of acute ulcers. Placebo-controlled studies have been carried out for 1 year.
Treatment of GERD. Symptomatic relief commonly occurs within 24 hours after starting therapy with Ranitidine Oral Solution 150 mg twice daily.
Treatment of endoscopically diagnosed erosive esophagitis. Symptomatic relief of heartburn commonly occurs within 24 hours of therapy initiation with Ranitidine Oral Solution 150 mg 4 times daily.
Maintenance of healing of erosive esophagitis. Placebo-controlled trials have been carried out for 48 weeks.
Concomitant antacids should be given as needed for pain relief to patients with active duodenal ulcer; active, benign gastric ulcer; hypersecretory states; GERD; and erosive esophagitis.
Ranitidine Oral Solution is contraindicated for patients known to have hypersensitivity to the drug or any of the ingredients (see PRECAUTIONS).
Symptomatic response to therapy with Ranitidine Oral Solution does not preclude the presence of gastric malignancy.
Since ranitidine hydrochloride is excreted primarily by the kidney, dosage should be adjusted in patients with impaired renal function (see DOSAGE AND ADMINISTRATION). Caution should be observed in patients with hepatic dysfunction since ranitidine hydrochloride is metabolized in the liver.
Rare reports suggest that ranitidine hydrochloride may precipitate acute porphyric attacks in patients with acute porphyria. Ranitidine hydrochloride should therefore be avoided in patients with a history of acute porphyria.
Laboratory Tests: False-positive tests for urine protein with MULTISTIX® may occur during therapy with Ranitidine Oral Solution, and therefore testing with sulfosalicylic acid is recommended.
Drug Interactions: Ranitidine has been reported to affect the bioavailability of other drugs through several different mechanisms such as completion for renal tubular secretion, alteration of gastric pH, and inhibition of cytochrome P450 enzymes.
Procainamide: Ranitidine, a substrate of the renal organic cation transport system, may affect the clearance of other drugs eliminated by this route. High doses of ranitidine (e.g., such as those used in the treatment of Zollinger-Ellison syndrome) have been shown to reduce the renal excretion of procainamide and N-acetylprocainamide resulting in increased plasma levels of these drugs. Although this interaction is unlikely to be clinically relevant at usual ranitidine doses, it may be prudent to monitor for procainamide toxicity when administered with oral ranitidine at a dose exceeding 300 mg per day.
Warfarin: There have been reports of altered prothrombin time among patients on concomitant warfarin and ranitidine therapy. Due to the narrow therapeutic index, close monitoring of increased or decreased prothrombin time is recommended during concurrent treatment with ranitidine.
Ranitidine may alter the absorption of drugs in which gastric pH is an important determinant of bioavailability. This can result in either an increase in absorption (e.g., triazolam, midazolam, glipizide) or a decrease in absorption (e.g., ketoconazole, atazanavir, delavirdine, gefitinib). Appropriate clinical monitoring is recommended.
Atazanavir: Atazanavir absorption may be impaired based on known interactions with other agents that increase gastric pH. Use with caution. See atazanavir label for specific recommendations.
Delavirdine: Delavirdine absorption may be impaired based on known interactions with other agents that increase gastric pH. Chronic use of H2-receptor antagonists with delavirdine is not recommended.
Gefitinib: Gefitinib exposure was reduced by 44% with the co-administration of ranitidine and sodium bicarbonate (dosed to maintain gastric pH above 5.0). Use with caution.
Glipizide: In diabetic patients, glipizide exposure was increased by 34% following a single 150-mg dose of oral ranitidine. Use appropriate clinical monitoring when initiating or discontinuing ranitidine.
Ketoconazole: Oral ketoconazole exposure was reduced by up to 95% when oral ranitidine was co-administered in a regimen to maintain a gastric pH of 6 or above. The degree of interaction with usual dose of ranitidine (150 mg twice daily) is unknown.
Midazolam: Oral midazolam exposure in 5 healthy volunteers was increased by up to 65% when administered with oral ranitidine at a dose of 150 mg twice daily. However, in another interaction study in 8 volunteers receiving IV midazolam, a 300 mg oral dose of ranitidine increased midazolam exposure by about 9%. Monitor patients for excessive or prolonged sedation when ranitidine is co-administered with oral midazolam.
Triazolam: Triazolam exposure in healthy volunteers was increased by approximately 30% when administered with oral ranitidine at a dose of 150 mg twice daily. Monitor patients for excessive or prolonged sedation.
Carcinogenesis, Mutagenesis, Impairment of Fertility: There was no indication of tumorigenic or carcinogenic effects in life-span studies in mice and rats at dosages up to 2,000 mg/kg/day.
Ranitidine was not mutagenic in standard bacterial tests (Salmonella, Escherichia coli) for mutagenicity at concentrations up to the maximum recommended for these assays.
In a dominant lethal assay, a single oral dose of 1,000 mg/kg to male rats was without effect on the outcome of 2 matings per week for the next 9 weeks.
Pregnancy:Teratogenic Effects: Pregnancy Category B. Reproduction studies have been performed in rats and rabbits at doses up to 160 times the human dose and have revealed no evidence of impaired fertility or harm to the fetus due to Ranitidine Oral Solution. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
Nursing Mothers: Ranitidine hydrochloride is secreted in human milk. Caution should be exercised when Ranitidine Oral Solution is administered to a nursing mother.
Pediatric Use:
The safety and effectiveness of Ranitidine Oral Solution have been established in the age-group of 1 month to 16 years for the treatment of duodenal and gastric ulcers, gastroesophageal reflux disease and erosive esophagitis, and the maintenance of healed duodenal and gastric ulcer. Use of Ranitidine Oral Solution in this age-group is supported by adequate and well-controlled studies in adults, as well as additional pharmacokinetic data in pediatric patients and an analysis of the published literature (see CLINICAL PHARMACOLOGY: Pediatrics and DOSAGE AND ADMINISTRATION: Pediatric Use).
Safety and effectiveness in pediatric patients for the treatment of pathological hypersecretory conditions or the maintenance of healing of erosive esophagitis have not been established.
Safety and effectiveness in neonates (less than 1 month of age) have not been established (see CLINICAL PHARMACOLOGY: Pediatrics).
Geriatric Use:
Of the total number of subjects enrolled in US and foreign controlled clinical trials of oral formulations of ranitidine hydrochloride, for which there were subgroup analyses, 4,197 were 65 and over, while 899 were 75 and over. No overall differences in safety or effectiveness were observed between these subjects and younger subjects, and other reported clinical experience has not identified differences in responses between the elderly and younger patients, but greater sensitivity of some older individuals cannot be ruled out.
This drug is known to be substantially excreted by the kidney and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, caution should be exercised in dose selection, and it may be useful to monitor renal function (see CLINICAL PHARMACOLOGY: Pharmacokinetics: Geriatrics and DOSAGE AND ADMINISTRATION: Dosage Adjustment for Patients With Impaired Renal Function).
The following have been reported as events in clinical trials or in the routine management of patients treated with Ranitidine Oral Solution.
The relationship to therapy with Ranitidine Oral Solution has been unclear in many cases. Headache, sometimes severe, seems to be related to administration of Ranitidine Oral Solution.
Central Nervous System: Rarely, malaise, dizziness, somnolence, insomnia, and vertigo. Rare cases of reversible mental confusion, agitation, depression, and hallucinations have been reported, predominantly in severely ill elderly patients. Rare cases of reversible blurred vision suggestive of a change in accommodation have been reported. Rare reports of reversible involuntary motor disturbances have been received.
Cardiovascular: As with other H2-blockers, rare reports of arrhythmias such as tachycardia, bradycardia, atrioventricular block, and premature ventricular beats.
Gastrointestinal: Constipation, diarrhea, nausea/vomiting, abdominal discomfort/pain, and rare reports of pancreatitis.
Hepatic: There have been occasional reports of hepatocellular, cholestatic, or mixed hepatitis, with or without jaundice. In such circumstances, ranitidine should be immediately discontinued. These events are usually reversible, but in rare circumstances death has occurred. Rare cases of hepatic failure have also been reported. In normal volunteers, SGPT values were increased to at least twice the pretreatment levels in 6 of 12 subjects receiving 100 mg intravenously 4 times daily for 7 days, and in 4 of 24 subjects receiving 50 mg intravenously 4 times daily for 5 days.
Musculoskeletal: Rare reports of arthralgias and myalgias.
Hematologic: Blood count changes (leukopenia, granulocytopenia, and thrombocytopenia) have occurred in a few patients. These were usually reversible. Rare cases of agranulocytosis, pancytopenia, sometimes with marrow hypoplasia, and aplastic anemia and exceedingly rare cases of acquired immune hemolytic anemia have been reported.
Endocrine: Controlled studies in animals and man have shown no stimulation of any pituitary hormone by ranitidine hydrochloride and no antiandrogenic activity, and cimetidine-induced gynecomastia and impotence in hypersecretory patients have resolved when Ranitidine Oral Solution has been substituted. However, occasional cases of impotence and loss of libido have been reported in male patients receiving Ranitidine Oral Solution, but the incidence did not differ from that in the general population. Rare cases of breast symptoms and conditions, including galactorrhea and gynecomastia, have been reported in both males and females.
Integumentary: Rash, including rare cases of erythema multiforme. Rare cases of alopecia and vasculitis.
Respiratory: A large epidemiological study suggested an increased risk of developing pneumonia in current users of histamine-2-receptor antagonists (H2RAs) compared to patients who had stopped H2RA treatment, with an observed adjusted relative risk of 1.63 (95% Cl, 1.07 to 2.48). However, a causal relationship between use of H2RAs and pneumonia has not been established.
Other: Rare cases of hypersensitivity reactions (e.g., bronchospasm, fever, rash, eosinophilia), anaphylaxis, angioneurotic edema, acute interstitial nephritis and small increases in serum creatinine.
OVERDOSAGE
There has been limited experience with overdosage. Reported acute ingestions of up to 18 g orally have been associated with transient adverse effects similar to those encountered in normal clinical experience (see ADVERSE REACTIONS). In addition, abnormalities of gait and hypotension have been reported.
When overdosage occurs, the usual measures to remove unabsorbed material from the gastrointestinal tract, clinical monitoring, and supportive therapy should be employed.
Studies in dogs receiving dosages of Ranitidine Oral Solution in excess of 225 mg/kg/day have shown muscular tremors, vomiting, and rapid respiration. Single oral doses of 1,000 mg/kg in mice and rats were not lethal. Intravenous LD50 values in mice and rats were 77 and 83 mg/kg, respectively.
Active Duodenal Ulcer: The current recommended adult dosage of Ranitidine Oral Solution for duodenal ulcer is 150 mg or 10 mL of oral solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) twice daily. An alternative dosage of 300 mg or 20 mL of oral solution (4 teaspoonfuls of solution equivalent to 300 mg of ranitidine) once daily after the evening meal or at bedtime can be used for patients in whom dosing convenience is important. The advantages of one treatment regimen compared to the other in a particular patient population have yet to be demonstrated (see Clinical Trials: Active Duodenal Ulcer). Smaller doses have been shown to be equally effective in inhibiting gastric acid secretion in US studies, and several foreign trials have shown that 100 mg twice daily is as effective as the 150-mg dose.
Antacid should be given as needed for relief of pain (see CLINICAL PHARMACOLOGY: Pharmacokinetics).
Maintenance of Healing of Duodenal Ulcers: The current recommended adult dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) at bedtime.
Pathological Hypersecretory Conditions (such as Zollinger-Ellison syndrome): The current recommended adult dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) twice daily. In some patients it may be necessary to administer Ranitidine Oral Solution 150-mg doses more frequently. Dosages should be adjusted to individual patient needs, and should continue as long as clinically indicated. Dosages up to 6 g/day have been employed in patients with severe disease.
Benign Gastric Ulcer: The current recommended adult oral dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) twice daily.
Maintenance of Healing of Gastric Ulcers: The current recommended adult oral dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) at bedtime.
GERD: The current recommended adult oral dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) twice daily.
Erosive Esophagitis: The current recommended adult oral dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) 4 times daily.
Maintenance of Healing of Erosive Esophagitis: The current recommended adult oral dosage is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) twice daily.
The safety and effectiveness of Ranitidine Oral Solution have been established in the age-group of 1 month to 16 years. There is insufficient information about the pharmacokinetics of ranitidine hydrochloride in neonatal patients (less than 1 month of age) to make dosing recommendations.
The following 3 subsections provide dosing information for each of the pediatric indications.
Treatment of Duodenal and Gastric Ulcers: The recommended oral dose for the treatment of active duodenal and gastric ulcers is 2 to 4 mg/kg twice daily to a maximum of 300 mg/day. This recommendation is derived from adult clinical studies and pharmacokinetic data in pediatric patients.
Maintenance of Healing of Duodenal and Gastric Ulcers: The recommended oral dose for the maintenance of healing of duodenal and gastric ulcers is 2 to 4 mg/kg once daily to a maximum of 150 mg/day. This recommendation is derived from adult clinical studies and pharmacokinetic data in pediatric patients.
Treatment of GERD and Erosive Esophagitis: Although limited data exist for these conditions in pediatric patients, published literature supports a dosage of 5 to 10 mg/kg/day, usually given as 2 divided doses.
Dosage Adjustment for Patients With Impaired Renal Function:
On the basis of experience with a group of subjects with severely impaired renal function treated with ranitidine hydrochloride, the recommended dosage in patients with a creatinine clearance <50 mL/min is 150 mg or 10 mL of Ranitidine Oral Solution (2 teaspoonfuls of solution equivalent to 150 mg of ranitidine) every 24 hours. Should the patient's condition require, the frequency of dosing may be increased to every 12 hours or even further with caution. Hemodialysis reduces the level of circulating ranitidine. Ideally, the dosing schedule should be adjusted so that the timing of a scheduled dose coincides with the end of hemodialysis.
Elderly patients are more likely to have decreased renal function, therefore caution should be exercised in dose selection, and it may be useful to monitor renal function (see CLINICAL PHARMACOLOGY: Pharmacokinetics: Geriatrics and PRECAUTIONS: Geriatric Use).
Ranitidine Oral Solution USP, a clear peppermint flavored liquid, contains 16.8 mg of ranitidine HCl, USP equivalent to 15 mg of ranitidine per 1 mL (75 mg/5 mL) in bottles of 16 fluid ounces (one pint) (NDC 65162-664-90).
Store between 4° and 25°C (39° and 77°F). Dispense in tight, light-resistant containers as defined in the USP/NF. Do not freeze.
MULTISTIX is a registered trademark of Bayer Healthcare LLC.
Amneal Pharmaceuticals LLC
Rev. 02-2017-01
PACKAGE LABEL.PRINCIPAL DISPLAY PANEL
ranitidine solution
Product Type HUMAN PRESCRIPTION DRUG Item Code (Source) NDC:65162-664
RANITIDINE HYDROCHLORIDE (UNII: BK76465IHM) (RANITIDINE - UNII:884KT10YB7) RANITIDINE 15 mg in 1 mL
BUTYLPARABEN (UNII: 3QPI1U3FV8)
SODIUM PHOSPHATE, DIBASIC (UNII: GR686LBA74)
HYPROMELLOSES (UNII: 3NXW29V3WO)
SODIUM PHOSPHATE, MONOBASIC (UNII: 3980JIH2SW)
PEPPERMINT (UNII: V95R5KMY2B)
PROPYLENE GLYCOL (UNII: 6DC9Q167V3)
PROPYLPARABEN (UNII: Z8IX2SC1OH)
WATER (UNII: 059QF0KO0R)
SACCHARIN SODIUM (UNII: SB8ZUX40TY)
SODIUM CHLORIDE (UNII: 451W47IQ8X)
SORBITOL (UNII: 506T60A25R)
Color Score
Shape Size
Flavor PEPPERMINT Imprint Code
NDC:65162-664-90 473 mL in 1 BOTTLE; Type 0: Not a Combination Product 03/12/2010
Labeler - Amneal Pharmaceuticals LLC (123797875)
Amneal Pharmaceuticals, LLC 963900878 analysis(65162-664) , label(65162-664) , manufacture(65162-664) , pack(65162-664)
Report Adverse Events, FDA Safety Recalls, Presence in Breast Milk
1 705610 raNITIdine 15 MG in 1 mL Oral Solution PSN
2 705610 ranitidine 15 MG/ML Oral Solution SCD
3 705610 ranitidine 15 MG (as ranitidine HCl 16.8 MG) per 1 ML Oral Solution SY
4 705610 ranitidine 75 MG per 5 ML Syrup SY
https://dailymed.nlm.nih.gov/dailymed/labelrss.cfm?setid=8f0bb213-6342-4fea-a080-24def590d1ba
1 65162-664-90

redpajama_set_name: RedPajamaCommonCrawl


I would like to start a series of posts relating to Korean gift-giving customs. In this gift-giving series, I will set out the appropriate types of gifts for different occasions according to Korean customs and explain the rationale or history behind. Today is the first post in the series and it's about giving canned food as a premium gift in South Korea.


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← Finn – Looks Like A Cinnamon Roll…
[Stitch Elsewhere] "Rupert Wong and the Ends of the Earth" Review @ Strange Horizons →
Rayne: A Racist Rando on my Lucifer Review
Posted on September 13, 2017 by Zeenah
Rayne isn't racist but she just knew that I'd be a "female of African descent" because I… talk about "racism". Wow. That's totally not racist at all — oh sorry, I meant that it's pretty racist and that Rayne can kiss my ass. 🙂
Imagine being so incensed by some random person on the internet's almost two-year-old review of a pilot episode of a show that's now starting season two that you write them not one but TWO separate comments explaining in detail how subpar you view their intelligence and accusing them of being easily traumatized by media.
Monday, after my mother and I finally got back home after waiting out Hurricane Irma in a shelter, some random person on the internet decided that that was the best time to try and school me on my initial review of Lucifer's pilot episode.
This woman, Rayne, wrote me two separate comments insulting my intelligence, my ability to understand dark aspects of fiction, and my understanding of misogyny and anti-black racism as a Black woman. Their two comments were insulting and unwarranted and at no point bothered to point out actual issues with my review (like the fact that I based my review on a leaked pilot episode…).
And this was all over a review I originally wrote two years ago for a show that I've since watched past the pilot and found interesting (if predictable).
Clearly, Rayne wanted attention so that's exactly what I'm going to give her.
Join me in dissecting her comments and feel free to make fun of them in the process.
Their comment opens with one of the two moments where Rayne concedes that maybe I'm not entirely incorrect, by saying that "Ok. I've seen this series and it sucks, though not fo all the reasons you mention."
Almost two years after Lucifer first aired, I wouldn't say that the show sucks. It's not Smallville, but I mean, that's the show that set the bar for ridiculous superhero shows. The problems that I bring up in my review were explicitly about the pilot alone, though. I wasn't saying that the entire show would be this much of a hot mess, only that I wasn't willing to sit around and wait to be proven wrong.
Rayne then goes on to be mad racist.
Really racist, yall.
With the risk of sounding racist, which I'm not in the least, I knew without seeing your picture that you would be a female of African descent. Because seriously only females of African descent could get so insulted by this "racism" as you are.'
Rayne isn't racist, but she totally knew without seeing my picture that I would be "a female of African descent" because I was talking about racism in a show that she doesn't even like. I wasn't "insulted" by the racism in Lucifer's pilot. I was annoyed. There's a difference.
One that Rayne doesn't seem capable of grasping.
The comments that Rayne is referring to, from my Lucifer review refer to the titular character being a condescending douche to a bunch of Black rappers and announcing that he doesn't like rap music. Excuse me for being annoyed that white people a world over feel the need to constantly announce how distasteful they find rap music and how subpar hip-hop is as a whole. It's not like people don't literally spill their deep-seated hatred of rap music at me the second they hear me listening to rap music.
They do.
All the damn time.
So forgive me for expecting the Devil not to be a racist, but while I didn't expect Lucifer to be into rap music (because of his whole piano lounge vibe), I also didn't expect him to be a dick about it. I was quickly proven wrong.
Rayne disagrees that barging into a Black rapper's home and talking shit about rap music is in any way racist, writing that:
I'm sorry but disliking hip hop music and more specifically this guys hip hop music with his gun toting posse… is NOT racism. It's merely saying dude your music specifically sux. If it had been a black dude saying to a white rapper you music sux, nobody would have even spoken about racism.
People like Rayne would've claimed racism. We know this. Because every time a white person doesn't rise to the top as the next Eminem or Vanilla Ice, they blame the mean ole Black rappers that just want to keep them at the bottom of the hip hop charts. And their white fans leap to coddle them and accuse Black people of racism.
Rayne then tells me to "[…] honestly put your too easily hurt feelings away" despite writing me a couple hundred words exhibiting HER hurt feelings about a review so old that I've finished THREE separate semesters of graduate school since then. (With straight As, natch.)
Rayne then goes off on this weird ramble about how it's a malady of this time that we apparently "cry racism for ever little criticism given to a person of different origins than European".
Rayne puts the word "white" in quotation marks a moment later because… whiteness isn't real?
And if you weren't sure about Rayne's ethnicity from the fact that she proceeded to lecture me about racism, she helpfully clarifies that by saying that, "[…] yes, you'll think but I'll even say it, I am as you ascertained correctly of European descent and yes, I too have the right to pronounce myself on Racism without being a racist, being white and all."
Rayne's out here acting like being of "European descent" makes her so damn sparkly special but meanwhile, I've got maternal Dutch ancestry and my paternal grandparents were British citizens. Being of European descent isn't anything to brag about… all things considered.
Then Rayne decides to tackle misogyny in Lucifer. Namely, that the real problem wasn't that Lucifer objectified Lauren German's Chloe at every chance he gets, but that German was a shitty actress. She literally says that I'm "so riled up about the sexually inappropriate comments that not once you mentioned the god awful acting of Lauren German".
Oh please forgive me Rayne. I forgot that mediocre acting on a mediocre police procedural was on the same level as the titular character of the show sexually harassing the female lead of the show (because that's what that is) throughout the pilot episode. Allow me to bend the knee to your superior –
I'm just kidding.
Rayne THEN proceeds to inform me that "As you've likely misjudged I am very much female and almost feminist in my behaviour yet somehow I do not feel the slightest bit offended by the sexual batter". Lucifer spends most of the pilot episode objectifying Chloe's body, embarrassing her in front of other men (because of her body), and speaking super inappropriately to her.
He's sexually harassing her. He does that well into season one.
It's gross and it's inappropriate. It's also out of character for the Lucifer introduced by Neil Gaiman and fleshed out by Mike Carey. I've read all of Lucifer. That was my bread and butter. I know the series inside and out. The titular character of that mediocre television show is Lucifer in name alone. To defend the show smearing Lucifer as a character by redicing him to someone that harasses women for fun is kind of super low.
I didn't think I could be more disappointed in Rayne, but here we are. She claims to be a feminist, but here she is, not only lecturing me about race/racism, but dismissing sexually inappropriate and unwelcome banter.
At the end of their first comment, Rayne does concede a few points to me. She agrees that Lucifer telling seven-year-old Trixie that her name is a "hooker name" was inappropriate (but still thinks that it "sets down his character pat") and that Lucifer shouldn't have been a police procedural where he solves crimes.
But wait, there's more.
It wasn't enough for Rayne to dismiss my comments about the pilot episode's racism and misogyny. In her first comment. Nah, this bored behind woman had to pop up in the comment section of my blog SEVEN MINUTES after her first comment to be a condescending douche in the key of Lucifer.
Let's get into this:
Rayne decides that she wants to tackle my comments on dehumanizing by pointing out that Lucifer isn't supposed to be human. Mind you, the one reference to a character being dehumanized was the way that Lucifer's psychiatrist Linda Martin basically reverts to this "must fuck Lucifer now" mentality when introduced to him. Lucifer is surprised when Chloe doesn't do this because ALL WOMEN apparently bow to Lucifer's superior fucking pheromones.
So I'm talking about misogyny. Right?
You know where Rayne takes it?
This character is supposed to be effing Lucifer! Fallen angel, guardian of hell, prince of darkness… he's not supposed to be human! Or behave like one… ugh, he's supposed to be a vile creature, hating humanity, abusing it, using it… playing on all our worst traits.
Another sign that Rayne literally knows nothing about Lucifer the character is that she doesn't understand that Lucifer is the most human of the angels in the DC/Vertigo shared universe. Lucifer isn't Duma or Remiel who kept themselves separate from humanity. Lucifer literally left Hell in order to walk amongst humanity. He's the only DC/Vertigo angel that really gets what it is to be human because he's always been close to us. He's not a being that hates humanity. He hated that he was stuck perpetually punishing people. He hated that he was forced into the role of the jailer, of humanity's boogeyman. It's literally right there in the Sandman and Lucifer comics.
If you don't know that single, simple detail about Lucifer and why his television portrayal is so at odds with his comic portrayal, consider keeping your mouth shut.
(I'm talking to you, Rayne.
For real.)
Rayne then goes on to try and paint me as a special snowflake scared of shit by referencing movies that are almost older than I am.
Please never watch wire in the blood or heck even seven or silence of the lambs, because what those serial killers do is SO Dehumanising, you'll be shocked beyond belief, far worse than funnily dangling someone from his stereotypically hip hop fat golden chain!
I think Rayne needs to reread my review because none of this even makes sense. I reference how portraying a psychiatrist suddenly going sex-wild (and telling him her client's secrets) for the chance to bone Lucifer felt dehumanizing and she is all like "well you couldn't handle real dark movies with serial killers".
But hey, I guess reading comprehension must be difficult when you're busy being a big ole bag of dicks.
Hopefully, now that Rayne has gotten the attention she craves, she'll move on and do something productive with her sad little life. Because none of this was any of that.
This entry was posted in Fandom and tagged fandom racism, Lucifer, name and shame. Bookmark the permalink.


The Marvel Comics superhero Spider-Man was created by Stan Lee and Steve Ditko and first appeared in Amazing Fantasy (August 1962) By the late 1970s, Spider-Man had become a successful franchise. At this time the fictional character had already featured in the animated series Spider-Man, a segment on the children's television series The Electric Company (called Spidey Super Stories), Marvel Comics licensed the character into a stream of electronic games.
Throughout the late 1990s, Marvel Comics suffered an industry slump with Marvel filing for bankruptcy, which explains the lack of Spider-Man games towards the end of the late 1990s. However by 2000 Marvel was profitable again and was gearing up to drop the Comics Code Authority and established its own rating system. They began seriously licensing its characters for major feature film adaptations (with the commercially successful X-Men film premiering on July 14, 2000). By the late 2000s, new Spider-Man games were in the works, being published by Activision, until January 2, 2014, when the license expired.
From Insomniac exclusively for PlayStation 4.
Gameloft weaves a tale of multiple Spider-Men fighting against the machinations of the likes of Green Goblin and Vulture. The game also ties into Marvel's 2014 multimedia crossover event, "Spider-Verse".
A Beenox-developed sequel to the open world web-slinging game. High Voltage Software is developing the 3DS version.
Announced at NYCC 2011, The Amazing Spider-Man game is an original story told after the 2012 movie. The console versions are developed by Beenox, the company that created Shattered Dimensions and Edge of Time while the DS version was developed by Other Ocean Studios.
Spider-Man: Web Of Shadows sees Spider-Man facing off against nemesis Venom and his army of Symbiotes with the help of both Marvel heroes and villains.
Spider-Man 2 is a sandbox game based on the movie of the same name.
A game based on Marvel's superhero and on the first movie of the Spider-Man franchise. It also featured many villains that did not appear in the movie.
A action-adventure game based on the Spider-Man comics, that follows an original storyline and features narration from Stan Lee.


Ashley Ward offers high quality centerless grinding services in-house and also for machine shops that lack grinding capabilities. Our centerless grinding services are for screw machine components such as input shafts, pump shafts, pins, and bushings. We can grind parts with diameters up to 3.5" in both profile and through-feed centerless grinders.
Throughfeed grinding, also known as thrufeed grinding, is the process of feeding a part through grinding wheels-- entering on one side and exiting through the other. Through feed grinding can be very efficient because it does not require an additional feed mechanism. However, with this feature, throughfeed grinding is used for simpler parts such as cylindrical shapes. When utilizing this machine for through feed grinding, the entire part can be placed through the grinder, allowing the part to be ground at its largest diameter.
Profile grinding is the most complex of our three grinding processes. It entails grinding multiple diameters on the same part at the same time. Precision ground parts can be produced with surface finishes above 1 RA. Our profile grinders can handle profile and centerless grinding of parts up to 20" long, our centerless grinding machines can handle bar lengths up to 14' in length. Tight tolerances of up to 0.0001" can be maintained in our grinding operations.
Infeed grinding is a method of grinding in which the part is held stationary while the wheel is fed into the workpiece. Infeed grinding is used to grind parts with relatively complex shapes with multiple diameters and tolerances. Because of these differences, we grind one portion of the part at a time. We work with a wide range of abrasive materials such as aluminum oxide, cubic boron nitride, and silicon carbide. Continuous efforts take place to increase efficiency in every aspect of our machining and finishing operation.
Maximum Diameter Profile Grind: 0.062" to 3.5"
Maximum Length Profile Grind: 20"
Awards Ashley Ward has received numerous Performance Awards from Whirlpool Corporation for its outstanding quality performance throughout the year.


Oklahoma Prescription Drug Possession crimes are common in our State. Statistics from a 2016 study show that almost 60% of overdose deaths in the state of Oklahoma are due to abuse of prescription drugs. These include many painkillers and anti-anxiety pills such as Oxycodone or Xanax. These habits not only threaten lives, but they can cost you. Some habits can be as much as $500 per day just to keep from withdrawal. This is a significant issue for many Oklahomans, which can have real legal consequences.
You can find Oklahoma's drug laws under Title 63 of the state statutes. This is the Uniform Controlled Dangerous Substances Act. It provides "schedules" to categorize the degree of danger for certain substances. Prescriptions pills generally fall into Schedule 2. The main characteristic of these drugs is that they either stimulate or depress the nervous system.
Because of the dangerous nature of prescription drugs, pharmacies generally have a set of rules to follow regarding them. First, the prescription must be valid. This means that the doctor must prescribe them knowingly and willingly. Second, once the prescription arrives at the pharmacy, pharmacy technicians must double check the dosage and patient name. Some pharmacies will check with other pharmacies at this point to make sure the patient is not pharmacy shopping.
Oklahoma has some very strict drug laws. Almost all drug possession crimes are a misdemeanor offense, unless the authorities also suspect intent to distribute or drug trafficking. This crime, while permanently on your record, also comes with a possible prison sentence of 1 year. However, if the crime is enhanced to trafficking or intent to distribute its a felony. Further, you will face fines and Court Costs. These can be anywhere from $1,000 to $20,000 depending on the amount of prescription drugs you possess.
Our criminal lawyers understand the gravity of felony drug possession charges. Oklahoma Prescription drug possession crimes can follow you through a lifetime and disqualify you from employment and even housing in some cases. Let us fight for your rights. We know the laws and can navigate the legal system in a way most favorable to you. Call today for a free phone consultation 918.743.2233.


Looking back, 2017 was a time when you could rely on certain constants. Golden State was going to play Cleveland in the NBA Finals, shaving blade preferences did not correlate with core values, and if you knew anything about digital marketing, you were fully pivoting to video. But what do we really know in 2019? I mean, who is Golden State going to play this year? Does Gillette even have a monthly subscription? (Yep.) And with the scandal around Facebook's false video metrics hitting us square in the face last year, what are marketers to believe about the future of social video marketing?


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Now reading: Your Complete Guide on How to Tell CBD Flower From Weed
Your Complete Guide on How to Tell CBD Flower From Weed
While many people are familiar with the term "cannabis flower," CBD flower is a newer term for most. Few individuals will be able to discern the difference between CBD flower and water soluble CBD.
If you don't know the difference, fear not, as both terms are frequently used interchangeably on a daily basis, and hemp legalization is still in its early stages throughout the country. However, knowing the difference between CBD flowers and marijuana is a different story.
In this article, we will provide you with a brief tutorial on how to tell the difference between CBD flowers and weed. Continue reading below to learn everything you need to know about the two and how ERTH HEMP can help you find the best water soluble CBD for sale from our wide selection of CBD vape juice 1000mg.
What is CBD Flower, and What Does it Do?
CBD flower is a type of cannabis bud that has less than 0.3 percent THC and helps individuals feel relaxed without the feeling of euphoria. While THC has the ability to radically affect your mood and perception, CBD has the potential to alleviate a number of aches, agony, and other ailments. As a result, hemp-derived CBD has become exceptionally popular for those looking for alternative methods of relief.
THC is just one of many cannabinoids in the cannabis plant, and CBD makes up a significant amount. While CBD flower contains a small amount of psychoactive THC, the high quantities of CBD help to moderate THC's effects.
CBD flowers are extracted directly from hemp plants and include the same beneficial terpenes and cannabinoids found in other CBD products. On the other hand, CBD flowers vary from many other CBD products in that they are clipped directly off the hemp stalks and do not require any additional processing or production.
CBD can be used in a variety of ways, but they are most commonly smoked. Hemp flowers can also be used to vape and in homemade items like edibles, lotions, and oils.
While research is still in its early stages, CBD has been examined for a variety of health advantages, including the relief of minor aches and tenderness. While the majority of the available information is still relatively new and more research is needed to fully comprehend CBD's benefits, early results state that CBD has several beneficial factors.
CBD vs. Cannabis
Because of their common ancestors, hemp and marijuana are often confused. However, the two are very different from one another.
Hemp is a cannabis plant that is harvested for its stalks, seeds, and flowers for commercial use, and the blossoms are collected for their high cannabinoid (CBD) content in particular. Cannabis, on the other hand, is mostly gathered for its calming, euphoric, and psychotropic effects.
Cannabis, which can generate euphoric effects and is prohibited in many states, should not be confused with CBD hemp flower. Unlike CBD flowers, cannabis is grown for its extremely resinous blooms, which contain a high amount of THC cannabinoids, and its stalks and seeds aren't employed commercially in textile sectors or as a food source.
While both belong to the cannabis genus, the THC content is what makes these two things very different. The most significant distinction between these two widely used cannabinoids is that THC gets you high while CBD does not. When we talk about CBD flower, we're referring to cannabis with an extremely low THC content (under 0.3 percent).
Now, let's take a look at some of the differences between CBD and cannabis that the average consumer will be able to identify.
The first and most important criteria for evaluating CBD flowers is the smell, as the pungent aroma is always a hallmark of quality. The scent, aroma, and potency of a CBD flower or plant are determined by the mix of terpenes.
When reviewing CBD flowers, keep in mind that high-quality flowers should have a very distinct and enticing aroma that stands out from other flowers. The robust and rich aroma indicates a high terpene content, which you will be able to detect with experience.
Visual Aspects
The cannabis plant has larger leaves and appears to be bushier, and produces many flowers. On the other hand, CBD flowers have thinner leaves that tend to concentrate near the top of the plant and grow significantly taller and produce flowers that are much less dense compared to cannabis.
CBD flowers of high quality should be green in color, though the shade might vary and are usually a mix of green and purple. Coloration that is bright and vibrant usually indicates a high-quality product.
Cannabinoid Content
More than 100 chemical cannabinoids are found in the cannabis Sativa genus; however, the concentrations differ between marijuana (cannabis) flowers and CBD hemp flowers. Tetrahydrocannabinol (or THC) is the most prevalent cannabinoid in cannabis flowers, and it's this cannabinoid that gives the plant its intoxicating effect.
Depending on the strain, THC levels in cannabis flowers might exceed 30%. On the other hand, CBD hemp flowers have a high CBD (non-psychoactive cannabinoid) content but a low THC concentration that does not exceed the legal limit of 0.3 percent.
Effect Profiles
As previously mentioned, CBD flowers have a low THC content, implying that they will not cause a euphoric feeling in the user. Simply put, CBD hemp flowers will not make you high, and you will instead feel more relaxed, attentive, and free of any bodily or mental discomfort. Ingesting cannabis, on the other hand, will get you high because of the high THC content.
Find the Best CBD Flower at ERTH HEMP
When it comes to choosing the correct cannabinoid product, it's critical to understand the key differences between cannabis and CBD hemp flower. Hopefully, with everything mentioned in the guide above, everything is now much more straightforward.
At ERTH HEMP, we work hard to ensure that our customers have all of the information they need to select the best CBD product for their specific needs. We have all of the CBD flower products you need for the best experience possible. We only use high-quality, THC-free materials from third-party sources with no superfluous steam additions with each of our products.
If you're looking for the best CBD flower available, look no further than ERTH HEMP. Contact us to learn more about our wide selection of high-quality CBD products and discover your favorite today.
Written by Daniel Joplin
What is the Strongest CBD Flower for Relaxation?
Beginner's Complete Guide: How To Take CBD Oil at Home


Perfectly charming and well cared for rambler in North Hill. You'll enjoy the bright, large living spaces with oak hardwoods throughout most of the home. The living room is complete with wood burning fireplace and lots of natural light. Open kitchen and dining room with doors out to patio and fenced backyard. Three good sized bedrooms with updated bath and a master with its own half bath. Two car garage along with ample off street parking. New roof! Large corner lot. Close to Normandy Park shops and restaurants. Great home!
Envision dinner with a view of the sunset over the Olympics and the Puget Sound. Each 4-Star Built Green townhome is unique, complete with custom iron and woodwork.


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Cecilia McDowall: The Girl from Aleppo – "National Children's Choir of Great Britain sing with real fervour and wonderful ensemble throughout" ★★★★ (Guy Rickards, Klassisk Musikk)
Cecilia McDowall: The Girl from Aleppo (CR054)
Review by Guy Rickards, Klassisk Musikk
Music inspired by or protesting appalling wartime events is nothing unusual, for example, Martinů's Memorial to Lidice, Schoenberg's A Survivor from Warsaw, Penderecki's Threnody to the Victims of Hiroshima or even Alfred Janson's A Baghdad Blues (Not for Blair, Not for Bush). Cecilia McDowall's cantata The Girl from Aleppo (2019), to a fine libretto by the distinguished author Kevin Crossley-Holland, joins a fine tradition, therefore. McDowall's inspiration is not like the impressive forebears listed above, but a very personal one, centred on the extraordinary story of the Kurdish refugee, Nujeen Mustafa, a onetime resident of Aleppo in Syria. (The work therefore has a connection to John Pickard's remarkable trio for flute, viola and harp The Gardener of Aleppo, recently released on BIS, CD2461). Driven from her home by the devastating civil war, Nujeen—despite suffering from cerebral palsy—trekked over 3,500 miles to find refuge and a new life in Germany.
The cantata is structured as a suite in five movements, which traverse the emotional journey of Nujeen as a Kurd and disabled teenager (Orphans of the World), through the terrors and events of her escape from the civil war (Thousands milling at the border; I'd never seen the sea before and A lost tribe pushed from border to border) to sanctuary in a new country (Everyday Wonders). It was written, very appropriately, for the National Children's Choir of Great Britain who sing with real fervour and wonderful ensemble throughout. The accompaniment is provided by violinist Harriet Mackenzie and pianist Claire Dunham. Mackenzie's playing is thrilling throughout, her experience playing in the crossover Kosmos Ensemble (try their marvellous CD 'Pomegranate' on the Nimbus label, NI6378) put to excellent expressive use here. At only 19 minutes long, this CD single is well worth a listen.
Guy Rickards, Klassisk Musikk, October 2020


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Empire Coach Menas Says Defense "Created Their Identity"
Dan Bahl Published: June 4, 2021
You may catch the ball, but you won't enjoy it.
That's the sentiment of what Albany Empire head coach Tom Menas told us on The Drive on Friday afternoon. When asked about what he liked most from the Empire's Week 1 win vs. Columbus last weekend, he praised the defense, and told us something that most fans may not have recognized right away.
He said his defense formed an identity for themselves in Week 1, and came to play every snap.
Menas praised the group of "big-hitters" for "dropping the hammer" in their Week 1 win, and told us how happy he was that his group gelled together so quickly and created a family atmosphere.
Speaking of atmosphere, he also marveled about the crowd at the Times Union Center. As a new coach, Coach T had no idea what to expect both from the crowd at the TU, and the people of the Capital Region as a whole. From everything he said, videos I saw on Twitter and people I've talked to, the 3,000 people in the stands sounded like a MUCH larger crowd during the game.
The Empire are back in action tonight! The team is on the road for the first time this season, visiting the Jersey Flight. Tommy Grady is coming off of an incredible performance, throwing eight touchdowns in Week 1, six of which went to Darius Prince, who made a huge impact on the offense right away. The team is back at the TU next Saturday, when Carolina comes to town. Make sure you visit https://www.albanyempirenal.com for tickets and more info!
TACKLE THESE: Check Out the Best Uniforms In Each NFL Team's History
Filed Under: Albany Empire, NAL, Tom Menas
Categories: Albany Area Sports


Urban Decay Naked Smoky – Take it or Leave it?
Let me start off by saying that I am a huge fan of Urban Decay eyeshadows. I own all of the full sized Naked palettes and I have loved them all. I own several eyeshadows from several different ranges, but the Naked palettes are what I reach for probably 98% of the time. They are gorgeous, go on beautifully both wet and dry, and I find them extremely wearable.
So naturally when I found out that they were releasing a new Naked – the Naked Smoky – I knew I wanted a piece of that! Joe and I went into Sephora and I was on the lookout. I honestly thought they would be sold out as it was so soon after launch, so my plan was to drool over the display and harass the staff about when they would be getting more stock. It was a pleasant surprise when Joe came up to me and said: "it's here…it's over there." I went over to find a display with quite a few available. It took me about 1.6 seconds to decide to buy it. I knew I was going to get it sooner or later anyway, so why not just get it over with? So what do I think of Urban Decay's latest?
The first thing I absolutely have to mention is the packaging. It is absolutely gorgeous. Urban Decay's packaging gets a little better with each new palette. This packaging is a reflection of its name; it is a semi-transparent plastic that has a smoky look. It has a magnetic closure that in my opinion is far superior to the snap closure of the two previous palettes, and it is better than the magnetic closure of the original Naked.
The shadows are beautiful. They are the same almost creamy consistency that Urban Decay is known for. The first 5 shades going from left to right are shimmery shades (High, Dirtysweet, Radar, Armor and Slanted). This is followed by two dark grey/black shades (Dagger and Black Market), great for lining and to smudge up for a smoky eye. This is followed by a dark purple shade (Smolder). The last four colours are matte shades (Password, Whiskey, Combust and Thirteen) the final two being highlight shades.
I think the shades are all very wearable, and let you go from a very natural to a very dramatic smoky eye. The shimmery shades in particular are very pretty, and go on very nice wet. The colours are all very buildable, so you can go as light or as dark as you're feeling, depending on the occasion.
The palette comes with a lookbook that serves as a guide to four different smoky eye looks. It's a good place to start, especially if you're a bit intimidated by the smoky eye look.
Verdict: Take it of course! Especially if you're already a fan of the Naked palettes, you'll definitely want to add it to your collection. Honestly, the Naked 3 is still my all time favourite and most used, but the Naked Smoky is a wonderful addition and I highly recommend it.
The Naked Smoky retails for $64.00 and can be purchased at Sephora and at select Shoppers Drug Marts.
As I talked about in my last post, I am really going to try to add content to this blog more often. I also mentioned that I was thinking about expanding the focus a little. For anyone that reads this regularly – I'm sure there are one or two of you (Hi Mom!) – you know that this space has never been about just one thing. It's more of a reflection of who I am, with lots of emphasis on my likes (reading, cooking, my own opinion).
I mentioned a couple of posts ago, that I have a newfound obsession with YouTube. This of course has been fueled by my obsession with beauty products. Bath, body, face, hair, makeup – you name it, I am interested in it. I love reading about it, watching videos about it, shopping for it, etc. So I figured that if I was going to stay true to the nature of this blog, that maybe I should open it up a bit to that side of my personality as well.
I should probably get this part out of the way – I am by no means and don't claim to be a beauty expert, just extremely interested in it, excited about it, and eager to learn more about it. I love to watch YouTube "Monthly Favourites" videos where all the beauty bloggers and vloggers talk about the new things that they have discovered that month and what they are loving and recommending to their viewers. I thought maybe I could do a little of that here. I do not upload videos to YouTube (aside from a few silly ones) and have no plans to start. I also have no plans to turn this into a "beauty blog." There are plenty of those out there written by people much more knowledgeable than me. I guess I just thought that if the inspiration hit me, or if I tried a new product that I was loving, or re-discovered an old product, I could let you know about it. Hopefully that appeals to you. If it doesn't, don't worry, because next week there will likely be a recipe or a book review or an opinion piece. Just as there are many different parts of my personality, there are many things to write about here.
To start I guess I'll just mention the gorgeous eyeshadow palette in the picture above. This is a pretty popular one, the Lorac Pro Palette. It used to be available at Sephora, but no longer is. It is hard to get your hands on in Canada unless you want to pay an arm and a leg for it. I actually had my wonderful cousin that lives in Arizona buy it and ship it up for me. If you live in the US, you can buy it at Ulta, or from Amazon. It retails for $42 US, and I have wanted this beauty for a long time. I was not at all disappointed.
This palette comes with 16 gorgeous shades – 8 matte shades in the top row, and 8 shimmery shades in the bottom row. The shades range from white to black and stick mostly to the neutral tones, but there is a very nice blue, a purple, and a beautiful coppery shade, along with a couple gold/bronze toned ones. The shadows are almost creamy in consistency, though they are definitely powder, and they are nicely pigmented – a little goes a very long way. If you are a beginner at makeup, or simply someone that wants to expand their collection, I would totally recommend this palette. It really has everything you need to create several looks, from light and natural to dark and smoky. This one for me was definitely worth the wait!
Hope you're all having a great day and the sun is shining wherever you are!


Compact clusters of 68 LED lights are built right into the "Your Speed" faceplate, delivering an 'impossible to ignore' speeder alert that is significantly more compact than traditional beacons.
In July, the city of Creswell installed two, new TC-400 Radarsigns that were purchased with grant monies through the Oregon Department of Public Safety Standards and Training (DPSST). The portable, battery-operated signs were moved at the beginning of September to new locations within the school zones as police prep for back-to-school congestion.
When you combine the beauty and freedom of the open country in Parker, Texas, with the autopilot drive of commuter residents, the sum is a speeding problem. While searching for a solution to the city's speeding problem, Captain Price landed on radar speed signs. Little did he know that a local philanthropic women's group was looking for an opportunity to give back to the community through the city's police department.


text:
Colobanthus es un género botánico que perteneciente a la familia  Caryophyllaceae. Comprende 39 especies descritas y   de estas, solo 25 aceptadas.

Taxonomía
El género fue descrito por Friedrich Gottlieb Bartling y publicado en Ordines Naturales Plantarum 305. 1830.  La especie tipo es: Colobanthus quitensis

Especies seleccionadas

 Colobanthus quitensis Antártida
 Colobanthus pulvinatus
 Colobanthus muscoides

Véase también
 Terminología descriptiva de las plantas
 Historia de la Botánica
 Características de las cariofiláceas

Referencias

Bibliografía
  Luteyn, J. L. 1999. Páramos, a checklist of plant diversity, geographical distribution, and botanical literature. Mem. New York Bot. Gard. 84: viii–xv, 1–278.

Enlaces externos

redpajama_set_name: RedPajamaWikipedia


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text:
Q: Committing hunks from inside of git add -i? Is this possible? It would be nice if I didn't have to switch back and forth between git-add -i and git commit when breaking apart hunks into different commits. Is there a better way to do this? Or am I doing something wrong?

A: As described in the git book, a simple git commit is still required after a git add --interactive session.
(With the following caveat:

Remember not to run 'git commit -a', which will blow away all the careful changes you've just made and simply commit everything
  )

Note: maybe git add -p (--patch) will be a little more convenient:

Interactively choose hunks of patch between the index and the work tree and add them to the index. This gives the user a chance to review the difference before adding modified contents to the index.
This effectively runs add --interactive, but bypasses the initial command menu and directly jumps to the patch subcommand.

Bonus, with Git 2.24 (Q4 2019), "git add -i" has been taught to show the total number of hunks and the hunks that has been processed so far when showing prompts.
See commit 8085050 (30 Sep 2019) by Kunal Tyagi (kunaltyagi).
(Merged by Junio C Hamano -- gitster -- in commit f0d407e, 11 Oct 2019)

add -i: show progress counter in the prompt

So, while you still need a separate commit step, at least you how far along you are during the completion of the interactive/patch git add session.

redpajama_set_name: RedPajamaStackExchange


text:
Mary Debenedetto
June 13, 1924 - December 31, 2021
Mary Debenedetto was called home to heaven on December 31, 2021, from her residency at Madison Point Nursing Care in New Port Richey, Florida. She was born on Friday, the 13th of June in 1924 to Lena (DiCorti) and John Asta in Brooklyn, NY where she was raised with her younger brother, Thomas Asta. As a child, her parents divorced, her mother remarried and gave birth to Antionette Chapel, Mary's youngest sibling. Her large extended family all lived very close to each other, some were right across the street, while others resided in the same apartment building. At the age of 17 she married Felix (Phil) DelCampo, who was from Jamaica, NY and together they raised four children, Robert DelCampo; Dolores DelCampo; Philip DelCampo and LeeAnn (Sheridan). Along with their children, Robert and Dolores, they left the big Italian family in Brooklyn and moved to NJ where they welcomed their two youngest children, Philip and LeeAnn. Mary loved being a homemaker. She loved family and always wanted everyone to be together, which brought her and Phil to leave NJ and make their way to LI, where Mary's side of the family had migrated to from Brooklyn to purchase homes and bask in the tranquility of suburban living. Her younger sister, Antionette, who was now living in Westbury, LI was raising a family of her own while living next door to their mother Lena, and across the street from other family members. Mary & Phil settled in Hicksville, LI where they eventually purchased a brand new 4-bedroom home. Mary came from a large extended family of aunts, uncles, cousins and lifelong friends. While raising her family, she was sure to instill in her children strong family bonds and traditions that were passed on to her by her grandparents, and which are still being passed down to her great and great great grandchildren today.
Her children were privileged to have a childhood filled with so many wonderful family memories that included their aunts, uncle's cousins and grandparents. Sundays were like a holiday gathering where homemade Italian food was plentiful and the love was endless. Mary loved entertaining, cooking, decorating her home and of course gardening. Whether it was her yard or terrace, the flowers were bountiful and beautiful. She was definitely a perfectionist at all she did, even when it came to taking care of herself. One would wonder, where did she find the time, but her hair, skin, nails and makeup was always flawless. At a time when nightclubs were all the rage, her and Phil along with members of Mary's family would go to shows and see famous entertainers. She was always dressed to the nines, looking like a Hollywood glam movie star. From the time she was a teenager through her 97 years she was stunning, expressing charm and class that wasn't taught, but came naturally. Mary worked hard all her life, not only in raising her family, but also in the work force. Although she did not work consistently until after her children were grown, she always managed to balance it out so everything ran like a well-oiled machine.
As time moved on Mary's children grew into adults, and eventually made her and Felix grandparents 8 times. By this time, Mary's parents and many of her aunts, uncles and cousins had passed away. In 1986 Mary and Phil retired and moved to Tarpon Springs, FL, as their son Philip and his wife moved to St. Petersburg FL. The close knit family values that she was raised with and which she instilled in her family proved itself, because eventually 2 more of her children and their family, as well as her sister and her family, also moved from NY to FL.
After losing her husband, Phil in 2008, Mary married Joseph Debenedetto in 2012. A few years after their marriage, Joseph and Mary moved to Atria Senior living in Hudson FL. Although Mary endured a bit of a struggle adjusting to an assisted living environment, she knew her husband needed the extra care and so she eventually embraced this new lifestyle and made it her home. As Joseph's health started to fail, Mary found herself alone again, as Joseph needed full nursing care and became a resident of Bear Creek Nursing Home, which happened to be the building next door to Atria. As always, Mary adapted and learned to except this heartbreaking change to hers and her husband's life. Being the wonderful caregiver she had been all her life, Mary spent all day, every day, sitting by her husband's side, and would return to Atria in the early evening. 2 years later, Covid hit and that was the end of life as everyone knew it. Prior to Covid creating havoc on the world, Mary had displayed signs of the onset of early dementia, and now needed the nurses to manage her daily medications. Due to the pandemic, Joseph and Mary would not see each for other for over 9 months. Mary did not do well during the period of Covid isolation. The dementia seemed to have escalated, she was very much confused, hallucinating and paranoid. Eventually she became completely run down having to be hospitalized and then transitioning to rehab, where she remained four 4 months. As it turned out, it wasn't so much that the dementia escalated, the doctor said the isolation took a toll on many of the elderly, especially their minds.
Mary did not return to Atria due to the inhumane neglect and solitude they had forced on their residents during Covid, but was so happy with her new apartment at Grand Villas of NPR Assisted Living. Mary's assisting needs were still minimal, but necessary, and now included help with washing and dressing, little reminders about mealtimes and to use her walker. Life was returning to normal for her and Joseph, as now Mary was visiting him once again. Her mental state vastly improved while in rehab – no more hallucinating or paranoia and the confusion was better. Although she still had dementia, she was so much better and participating in some of her favorite pass times again, such as knitting, playing cards, doing word searches and of course…going out for lunch and shopping dates with her daughter. In January of 2021, just six weeks after moving into her new apartment, Mary fell and broke her hip. After surgery and rehab, it was apparent that she needed to reside full time in a skilled nursing facility (Madison Pointe) as she was an 100% fall risk and the dementia allowed her to forget to use her walker. For her safety, Mary was confined to a wheelchair with daily physical therapy using her walker. But still, Mary could not accept this lifestyle and grew very anxious and unhappy. Once her hip fully healed, the mission was to have her husband transition from Bear Creek to where she was now living (Madison Pointe). She knew it was a mission that was being worked on and was so happy waiting for the day it would become a reality. It took a few months, but it did happen, and they were finally together again after years of living apart.
Sadly, Joseph died just 6 weeks later. Mary only knew that he was sick and that he was taken to the hospital. At times she would say that Joe passed away and then start to talk about something else. Sometimes the dementia was a blessing, as she didn't have to endure the pain of losing him; however, she still missed him terribly and felt very lonely.
Eventually, Mary finally came to her own and was known to the staff and residents alike as the life of Madison Pointe. She was content, and with that came a personality that was very different from ever before. She was calm, easy to please and very agreeable. The nurses would say that she was their social butterfly and loved to make friends. Mary was very healthy, and at 97 years old that is a rarity. The dementia was now to the point where at times she believed and said things that weren't so, but she also was still quite lucid at the same time. Sometimes she would realize that what she said didn't make sense and laugh about it. She was adorable. Her sense of humor was delightful, and her innocence was endearing. The simplest of things made her happy, such as eating an ice-cream or sipping a milk shake. But make no mistake about it, Mary was smart and was still very much the mom to her children that she always was. If they needed advice or were troubled about something, it was almost like the mom gene was immediately awoken. She knew just what to say to comfort and guide.
Anyone who ever knew Mary can tell you that her favorite thing to do was to dance…and she was great at it. Music moves the soul, and it sure did move hers, along with rest of her body. Back in the day, she played vinyl's all the time. She loved music. Eventually, it was on to cassettes and CD's. The car radio was always on whenever she was out and about. Dancing and Mary went hand in hand right up to her last week of life here on earth. She was sitting in her wheelchair during the Christmas party at Madison Pointe with her hands thrashing around above her head, and her derriere wiggling about in the seat singing, "Shake, Rattle and Roll". The charge nurse was tickled to see this and asked her, "Miss Mary, what has gotten into you?" She replied, "Well, someone has to entertain them" (referencing the other residents). Mary was always the true life of all the parties and gatherings she ever attended.
Mary didn't have the easiest childhood, and yes, she had her share of sorrow along the way. You would never know it by looking at her face. Towards the end of her time here on earth, she seemed like the happiest person in the world. And maybe she was.
In addition to her 4 children and 8 grandchildren, Mary is survived by 11 great grandchildren and 3 great great grandchildren.
To those who knew her and loved her, they will meet her again in heaven. And they will know where to find her…where the sounds of music, laughter and joy are heard nearby.
Date: Monday, January 10, 2022
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"I recently traveled to Florida to attend the funeral of a dear relative. It was not an easy trip to make, as I am disabled and travel with my faithful service dog, Whistler. The staff at Michels and Lundquist were so kind and thoughtful and welcomed Whistler and I into their establishment and made sure we were both comfortable. The service was wonderful, so personalized and dear Aunt Glenda looked so beautiful and peaceful."


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Do you provide a newsletter subscription feature to your customers? If not, then this extension will allow you to remove all newsletter links and options from your opencart website. When you install this extension, all the newsletter links and options in the frontend default theme will be removed entirely.
* Simple VQMOD/OCMOD script plug and play. No files to edit or overwrite.
* No external VQmod required.
* Easy installation through the admin page.
* No files are overwritten.
* Removes Newsletter in footer.
* Removes Newsletter from the shortcut menu in Account page.
* Removes option to subscribe to Newsletter from Register Account page.
* Removes option to subscribe Newsletter from Checkout page when registering a new account.
Login into your administrator dashboard.
2. Go to Extensions->Extension installer.
3. Upload the upload.ocmod.zip archive to install the extension.
4. If installed correctly, you should see a success message.
If it isn't working or you get errors, then your theme may need adjustments for it to work. Please use our support page to contact us, and we will adjust for your theme.


I like the home dog Saints.
I am ever so close to switching to the 'Aints.
I'm going hunting for big points with Scott. I'll bring the beers. Give me the Browns.
I'm sticking with the Dak & Zeke Show and the cowgirls to blow up the mirage that is the Packers run defense.
Ugh, Joe Haden is out.
There is still time to get on the Jesters this evening.


I never truly used Instagram, but once I learned that it has over 100 million customers, I had no choice yet to start utilizing it - Instagram Followers And Likes Free Trial.
Well, not just can you take advantage of it to advertise your individual brand, but you can utilize it to promote your business as well.
When I first began utilizing it, within the very first few days my account reached one hundred followers, yet after that it gradually quit growing. I was still getting a couple of followers a day, but it had not been substantial sufficient to obtain any type of grip as my one hundred followers led to no more than thirteen like on any one of my photos.
So, over the weekend break I began finding out whatever regarding Instagram: what causes users to like pictures, exactly what causes them to comply with others, as well as exactly how you can obtain more people to discover your photos.
I after that used exactly what I learnt how to my account. Now, I am continually getting over two hundred followers a day, as well as my photos could easily heal over a hundred like. Best of all, I have the ability to achieve these results by only complying with 5 people (I know, I need to begin adhering to more people).
This is probably one of the most evident way to grow your Instagram account ... 20% of all customers of the service are likewise on Facebook.
When you attach your 2 accounts to each other, your Facebook good friends will certainly notice it and also begin following you on Instagram also. Based on the data from my very own account, 3% of your Facebook buddies will start following you on Instagram. If you happen to post a condition upgrade on Facebook asking individuals to follow you on Instagram, that number could boost to just under 5%.
If you desire your photos to obtain even more like or remarks, you should begin engaging with other users. Before you do, you have to understand that individuals do even more liking compared to commenting. Every second people develop 575 new like versus 81 remarks.
So, if you put in the time to talk about someone else's profile, that person is more probable to come back to yours. Individuals will not only discuss your photo if you talk about their own, however they are 401% more likely to follow you in this instance.
For each one hundred like I did on arbitrary pictures of various other individuals (whom I really did not comply with), I produced 21.7 suches as on my images and also 6.1 even more followers. I did not have to follow individuals back for this to work.
By analyzing my account information on Statigr.am, I discovered that by liking thousands of images of people that just weren't my followers, not just did I enhance the variety of my followers, but I also had individuals from beyond my friends' network liking my photos.
Since I was liking numerous pictures a day from random accounts that I really did not comply with, 43.26% of all my like and also 31% of all discuss my photos came from people that weren't my followers.
From analyzing 46 users and over 1,000 pictures on Statigr.am, I have actually figured out that Monday at 5 PM, PST, is the very best time to post a picture. That is when you are more than likely to get the greatest variety of remarks as well as suches as on your pictures.
The 2nd most preferred time to post a picture is either on Wednesday or Thursday at 3 PM, PST.
Likewise, an image is the most energetic during the initial 3 hours. 46.15% of all remarks happen within the very first hr, as well as 69.23% of all comments take place within the first three hrs. So, if you cannot get traction within the very first three hours of publishing an image, it is probably not mosting likely to acquire grip later on.
By evaluating the similarity over 1,000 photos, I have actually found that images that have to do with lifestyle (expensive vehicles, residences, living an elegant life, and so on) or that are individual have the tendency to obtain the most engagement. Images that don't include either of those two aspects have the tendency to obtain 11.4% fewer likes.
Images like the one above are multiple photos integrated into one. You could develop them with applications like Diptic. My business companion Hiten Shah posted the picture over and also promptly got 75 like as well as 5 remarks. Pictures like those tend to get 19.41% even more like and 22.4% more comments compared to photos that typically aren't collage-like images.
If you wish to obtain the most traction with your photos, take the additional time to take numerous shots then incorporate them right into one photo.
If you want to expand your account by a few hundred followers a day, the best means to complete it is to arbitrarily like countless pictures a day. This is a tedious task, yet as you could see from the development of my account, it works actually well. The biggest imperfection with this design is that 16.6% of your followers will certainly be phony: they will certainly either not take part or they will certainly be robots.
If you comply with the pointers over, you'll optimize your Instagram likes and grow your follower matter much faster compared to if you simply shared your shots randomly.
So, what other ways can you boost your like as well as followers?


The Skardu Valley is located in Gilgit-Baltistan, Pakistan. The valley is about 10 km wide and 40 km long. It is at the confluece of the Shigar River and Indus River. It surrounded by the large Karakoram Range. With the nearby lakes and mountains, it is an important tourist location in Pakistan. Skardu is the main town of Baltistan along the wide bank of the river Indus. Skardu is the largest district of the Northern Areas. Baltistan is home to some of the highest peaks in the world, the Karakoram Range, Skardu is very popular with Mountaineering Expeditions. It is equally popular with high altitude trekkers, who treks to Baltoro Glacier, K2 Base Camp and Concordia. Skardu by road, lies approximately 5 hours away from Gilgit and 10 hours drive from Besham.
From Chilas we travel on towards Skardu and on the way make a stop at Nanga Parbat View Point and confluence of the world's 3 highest mountain ranges (Karakorum, Himalaya and Hindukush) including the confluence of Gilgit River into the Indus. Shortly after this point we turn right to follow the Indus River towards Skardu. This is the most breath taking part of the journey where you see villages on both sides of the mighty Indus and there are rope bridges connecting the two sides. We reach the Kachura Lakes for a brief stay before continuing on to Skardu where we will stay for night.
From Skardu, we move towards Deo-Sai stopping briefly at Satpara Lake. Then it is a constant climb to more than 4000 metres to reach the plateau. We shall stop at Bara Pani Bridge for tea break and try to reach Shausar Lake (depending upon weather conditions) before returning to Skardu.
After breakfast we leave for Shigar valley, a contrast of greenery as well as desert known as the Cold Desert Shigar. Crossing the River Indus and driving through a sandy land, we reach in green and fertile Shigar Valley. At Shigar, we will visit the old mosque and Shigar Fort residence. We return back to Skardu in evening and stay there for night.
After breakfast we check out and start our return journey following the Indus River. We reach the KKH and drive to Chilas for a rest and lunch break. After lunch we continue our journey towards Besham for night stay.
From Besham we resume our journey towards Islamabad passing through Mansehra, Abbottabad and Havelian we will reach Islamabad at our designated drop off place.
Personal effects for Warm/Windy/Rainy conditions should be carried by clients. Insect's repellent, Sunburn lotion etc. Following are recommended for.