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Coverage of President Joe Biden, left, has been much more positive than that of former President Donald Trump, right, according to a report from the Media Research Center. (Doug Mills - Pool / Getty Images; Joe Raedle / Getty Images)
Study: Trump Had 89% Negative Press First 3 Months of Presidency, Biden Has 59% Positive
By Jack Cowhick April 19, 2021 at 3:17pm
As if anyone needed any more evidence that the mainstream media are biased against conservatives, this study proved it.
A Media Research Center study published Monday shows a stark contrast in media coverage from the first three months of former President Donald Trump's administration to the same timespan of President Joe Biden's term.
According to the study, evening news broadcasts have pampered Biden with 59 percent positive coverage of his administration, while just four years ago the Trump administration received a less-than-comfortable 89 percent negative coverage.
The MRC said it "reviewed all ABC, CBS and NBC evening news coverage of Biden and his new administration from January 20 through April 9" — the same process it underwent in 2017 for the same study — with a total of 726 minutes of coverage.
However, it said, while this figure made up almost 20 percent of news airtime, it was "just a small fraction" of the 1,900 minutes of coverage those same programs gave to Trump and his administration in 2017.
Thankfully, the MRC has done the heavy lifting, putting together a compilation of the mainstream media's most biased reports to date.
While the featured coverage of Biden consists of a celebration of historic moments and tales of triumph over trauma, the same cannot be said of the media's treatment of the prior administration.
In 2017, the MRC tallied a total of 1,687 "evaluative comments" regarding the Trump administration, 89 percent of which were negative while 11 percent were positive. Now, the media has turned down the heat, with just 264 such comments being tallied on the Biden administration and over half of them positive.
Have the establishment media held the Biden administration accountable?
Yes: 2% (8 Votes)
"These much lower numbers signify a news media that's not trying to drown out the White House with its own aggressive criticism, as was their standard practice in 2017," the MRC report said.
The mainstream media seemingly struggled to find a way to put a positive spin on Biden's ongoing border crisis, with a reported 82 percent of that topic's 115 minutes of coverage being negative.
However, this is still a massive uptick compared with the reporting on Trump's immigration policies. Out of 120 minutes of coverage, a whopping 93 percent was negative.
On the surface, the negative coverage Biden received might seem like it proves the media are at least trying to aim for some form of impartiality. However, this is not the case. In one out of every six instances of the Biden administration being criticized, the negativity came from reporters representing a view to the left of the president, the MRC found.
Coverage of the Biden administration is also more policy-oriented now than it was four years ago under Trump, with 90 percent of airtime being dedicated to policy decisions. The Trump administration received just half of that, with 45 percent of its airtime related to policy.
Somehow, the mainstream media also avoided tackling rhetorical issues that would have sparked fury with reporters had Trump made similar comments.
When Biden essentially called Texas Gov. Greg Abbott, Missippi Gov. Tate Reeves and like-minded Americans "Neanderthals" for shunning mask mandates and supporting personal choice, the mainstream media spent just over a collective minute of airtime on the remark.
Biden's false claim about Georgia's new voting law being a modern-day version of "Jim Crow" also received a microscopic 39 seconds.
Even worse, none of that coverage was critical.
The mainstream media refuse to admit it, with CNN writing in March that "the media won't give Biden a free ride," but the "Big Three" — ABC, CBS and NBC — are some of the most biased news organizations in existence, essentially acting as the state propaganda arm.
The MRC ended its report with a mic-drop, writing, "Journalists like to claim they're 'fearless' in confronting those in power on behalf of the public. But it's not fearless when journalists only use their influence to harass politicians from one political party and not the other.
"That's actually twisting journalism to suit a blatantly partisan agenda."
It couldn't be more right. Biden is rarely criticized regardless of how much he hurts the American people with his policies, and when he is it's almost always because someone believes he isn't radical enough. Thankfully, though, organizations like the MRC exist to expose this.
Biden administration, conservatives, Donald Trump, establishment media, Joe Biden, liberal media, liberals, media bias, media watch, Trump administration
Jack Cowhick
Jack Cowhick was a contributor for The Western Journal. He is a student in the DFW metroplex in Texas. He is a contributor at Lone Conservative.
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As you know, the 1.06 update was pushed on Wednesday, and while some changes were beneficial to the experience, others negatively impacted it.
- We have identified a bug which caused animations to play incorrectly and hits not to be detected: this has been fixed and is included in the 1.07 update.
- from a gameplay side, we probably made too many changes at the same time; we have therefore reverted changes made to the dodge mechanic, and done some tweaks to ranges and guard impact of previously changed attacks.
We are actively working on other remaining issues (loading and disconnect issues in Combat Trials, amongst others).
Just wanted to say thank you all so much for responding so quickly to player feedback, and being able to carefully evaluate what should be changed. Looking forward to what will happen next!
Any word on the timing for a PS4 patch?
Thanks for being quick on the draw. My only request is revert Kahlt or at least make it rewarding for skilled players. Protection is meaningless in a pvp game, and is an absolute anti-thesis to how the rest of absorb works with ghost damage.
Glad to see some of the changes with bad side effects being reverted.
Might as well revert kahlt too as it does not adress any of the points you think it does and does not work well with absorb mechanic.
Sure, absorb might be the easiest to land but actually is the hardest to utilize. It also requires timing just like parry or avoid, especially if the opposition has breaks readily available. Then you have to keep some stamina in reserve or you get one break into the face without chance of escape.
The stamina gain simply should be higher for an ability where you risk health, dont get an instant benefit aside stamina and dont have an easier or guaranteed punish. You might not even use the protection (which is capped and limits gear choice) if you play well and you are not supposed to get hit anyway.
If there should be mechanic at all next to the stamina gain then I would like to see a damage and/or attack speed buff in relation to your ghost health.
A improvement to parry is still needed, or better balancing, parry is still pretty dang underpowered for forsaken, sure it has a chance to get a hit but the window is super short and fast moves still break threw it.
The windows for the skills are all the same, afaik. And any special can be broken by fast moves, at least yours stops their combo.
it does not have just a chance, it is a guaranteed side kick. No other defensive ability has a guaranteed punish like parry, you could remove the stamina reward and it would still be strong. If you have issues landing a punish then you need to think ahead and buffer attacks. Parry is fine.
Parry is single handedly the strongest ability in the game. The nerfs did nothing to address the generous windows of activity and the minimal windows of recovery. Idk what short windows you refer to.
You can still feint a parry and if the forsaken buffered an attack they will still hit you first.
You can feint a parry and if the forsaken doesn't attack they can still just parry again and get that hit if its around the speed of a side kick.
Liddykins' is spot on. Windfall is in a good place now, but Absorb has been utterly trashed on with the latest update.
I love the changes and tweeks you guys have made to gameplay, but i have been experiencing more connection issues since the release of 1.07. Il get maybe one or two good matches and then the system starts to lag and hits start to register late. Most of the time when i que up combat trial it puts me in an infinite load screen or just takes me back to the open world. I love this game but its mostly unplayable for me now with these issues im facing.
Patch is already out on PS4.
Tried 10 matches, today, after DLing 1.07.
I had the impresison that at least some of the netcode changes of 1.06 were rolled back. Kinda felt like 1.05, as far as the connectivity goes.
I hope it is improved in 1.08.
You guys keep talking about using a side kick after a parry. I don't use side kick of for that matter have it in my deck. So yeah try using a parry and then trying to use something else besides broken moves, side kick being one of them. In any case I am not the only player who feels like parry is underpowered. I am guessing that you two don't main a forsaken? Probably a windfall & khalt.
Also as I previously stated fast moves can nullify a successful parry with ease, lag punches also can, before the patch shockwave could interrupt it as well.
If you can't time your shockwave or parry you're not going to do any better with the other abilities. The difference is yours' stops them in their tracks AND leaves them open.
Leaves them open to what, a jab? One single attack? Wow amazing.
Doesn't matter how often you parry when you can only give them a tiny piece of damage before they go right back to doing whatever they were doing before.
a succesful parry = guaranteed side kick = ~130 damage plus any follow up.
This is the second or third time I've heard someone mention broken moves, what exactly are they talking about?
Imagine being a Kahlt, where you can absorb as often as you want but not only can you not even give them damage guaranteed, you can bring yourself to 1 health with it.
Obviously a joke video and idk why but it goes to 3 seconds. Skip to 53. Anyway, Forsaken is so straight forward to use I use it ironically now. You can get a charged attack immediately off of parry. Parry leaves players open to a plethora of things, you just gotta lab with it and see what you get.
...So yeah try using a parry and then trying to use something else besides broken moves, side kick being one of them.
I am guessing that you two don't main a forsaken? Probably a windfall & khalt.
I went from Forsaken to Kahlt after getting to combat trial 15 because I realized Forsaken as it stands is a crutch. I won a game where all I did was parry -> side kick -> low kick. I could feint the low kick into side kick too, so I could juke players out with it. Forsaken is the only style I've ever played where I can win with two moves. Also side kick isn't what's broken about it, nor is buffering attacks. The issue is the small window for players to flick parry wildly and reap rewards with it.
1) They have trouble counterplaying a move. This could be anything, common offenders being Multi-hit and charges. They have counterplays, but it relies on having a balanced deck or good playstyle.
2) Breaking charged attacks. You can break charged attacks with certain moves, busting through their super armor and letting you unexpectedly beat them up to their surprise. Excellent in neutral against tanky players, but its situational as you'd need a deck designed around it to do it frequently.
Again let me just say this again....I am NOT using Side Kick, just because it is the only move that allows a guaranteed hit. And to basically tell me that that is the only move I am limited to should tell you how small the parry window is.
So after a parry my only two options are Side Kick or feint is basically all that I am hearing. Which since I DO NOT have a interest in using that move, i'm limited to using parry as a way to feint a move. That literally proves my point that parry is under powered despite the claims.
Two. Use a slow super armored move which is predictable and very slow, which means it will be avoided, or parried right back.
I'm not using side kick.
You can do anything of similar speeds or faster than side kick and its guaranteed.
Literally if you have any move faster than side kick you can use it. Side Kick isn't broken, Parry is just really gud lol.
I feel like the best way to make khalts damage absorption relevant would be to add a damage multiplier that lasts 3 seconds or if you get hit before the seconds are up then you lose it. That way absorbing the hit would be worth it if you can make ur next attack hit harder.
Developers when you stop laughing at people and make a normal ping ?? I'm disappointed.
Parry is the strongest style in the game.
You aren't utilizing it to it's broken potential.
again, you dont have to react, just buffer the attack right after the parry. no skill or reaction time required at all. there are plenty of 100+ damage moves that will connect in that timeframe.
Are you even reading what other people are saying? Because we've said time and time again that the things you are spouting are wrong and given you the various reasons why.
You can do any attack with a similar speed to side kick and it will be guaranteed. Even moves with special properties, like charged attacks, some of the slowest moves in the game because they're made for tanking, can guarantee off of Parry.
Even if they feint your parry and go for an attack, if you buffered the attack you will still hit them first.
Parry needs longer recovery frames. Its too efficient, as you can parry someone, parry again, and still get a light hit, or even worse you can panic parry both direction and since it happens so damn swiftly get a completely luck based punish, something no other class can do from mashing their ability wildly.


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SYK Pathway
In Thailand, both scrub typhus and murine typhus are endemic, wit
Posted on May 31, 2018 by sykp8676
In Thailand, both scrub typhus and murine typhus are endemic, with the former being more prevalent and often presenting severe manifestations including multiorgan dysfunction,
which resemble septicemia from other bacteria and leptospirosis.[11] Because our patient had the triad of rickettsial infection symptoms, it might not have been difficult to consider scrub typhus as a candidate diagnosis from the initial observations upon admission. However, it should be emphasized that murine typhus occasionally brings life-threatening PARP cancer conditions. The mortality rate for murine typhus is reported to be 4% without use of appropriate antibiotics and remains at 1% even when antirickettsial antibiotics are given.[12] Thus, prompt administration of antirickettsial antibiotics is strongly recommended in cases where rickettsiosis, including not only scrub typhus but also murine typhus,
is suspected. Although most cases of murine typhus are self-limited or mild, our patient developed Olaparib mouse shock and acute respiratory failure immediately after admission. The severity of murine typhus has been associated with male sex, African origin, glucose-6-phosphate dehydrogenase deficiency, older age, delayed diagnosis, hepatic and renal dysfunction, central nervous system abnormalities, and pulmonary compromise.[12] In addition, the risk increases by at least 20% with each day of delay in doxycycline treatment for rickettsial infection after presentation.[13] Our patient matched the parameters of male sex, older Quinapyramine age, hepatic and renal dysfunction, and delayed diagnosis. We also investigated glucose-6-phosphate
dehydrogenase deficiency, but none was found. The tetracycline family of drugs, such as minocycline and doxycycline, are used as first-line therapy for rickettsiosis. We considered rickettsiosis as a differential diagnosis in this patient and started treatment including minocycline, while ciprofloxacin was added after obtaining positive results in PCR assays for the rickettsial gltA and 17 kDa genes. In this case, we did not exclude the possibility of infection with other Rickettsia sp. related to Rickettsia japonica, which are known to be present in Thailand,[14] thus minocycline and ciprofloxacin were administered. For fulminant Japanese spotted fever, some physicians in Japan have recommended combination treatment with minocycline and ciprofloxacin.[15, 16] Although the superiority of that combined therapy for Japanese spotted fever, as compared to minocycline alone, has not been confirmed with established evidence, those reports noted an expectation of increased antirickettsial activity with the addition of ciprofloxacin. On the other hand, treatment regimens with doxycycline plus chloramphenicol or ciprofloxacin did not improve the effectiveness of doxycycline in 87 murine typhus patients.
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A similar route has been demonstrated for the selenate-respiring
A similar route has been demonstrated for the selenate-respiring bacterium T. selenatis (Lowe et al., 2010). In T. selenatis, electrons are mediated between membrane-bound quinol:cytochrome c oxidoreductase (bc1-complex) and periplasmic selenate reductase (Ser) by the 24-kDa di-heme cytochrome cytc-Ts4. In the photosynthetic bacterium R. sulfidophilum, electrons are transferred in the opposite direction on the oxidation of dimethyl sulfide to DMSO. Electrons
are shuttled from the periplasmic DMS dehydrogenase to the membrane-bound photosynthetic reaction center, mediated by the soluble cytochrome c2 (Creevey et al., 2008). In the present paper, we describe the purification and characterization of the cytochrome c discussed above. MS gives a molecular weight of about 9 kDa rather than PD98059 ic50 the 6 kDa found by SDS-PAGE. We denote this protein cytochrome c-Id1. Electron transfer to chlorate is thermodynamically feasible from its Natural Product Library order estimated redox potential, and we demonstrate its ability to serve as electron donor for purified chlorate reductase. Ideonella dechloratans was obtained from the Culture Collection of Göteborg University, Göteborg, Sweden. Cells were cultured anaerobically (8 L) and harvested by centrifugation at 8000 g for 15 min. Wet
cells (20 g) were resuspended in 90 mL of 0.3 M Tris-HCl, pH 8.1, containing 20% (w/v) sucrose and 1 mM EDTA. The suspension was placed at room temperature for 10 min, followed by centrifugation at 8000 g for 10 min. The pellet was resuspended in 90 mL ice-cold 0.5 mM MgCl, and was kept on ice for 10 min.
Soluble proteins were extracted by Carbachol centrifugation at 8000 g for 20 min and ammonium sulfate was added to the protein extract to 40% saturation. The solution was stirred on ice for 30 min, followed by centrifugation at 18 000 g for 10 min. Ammonium sulfate was added to the supernatant to 85% saturation and the solution was stirred on ice for 30 min. Precipitated proteins were pelleted by centrifugation at 18 000 g for 10 min, and resuspended in 10 mL sodium phosphate (50 mM, pH 7.0) containing ammonium sulfate (0.92 M). The solution was applied on to a Phenyl Sepharose 6 Fast Flow (low sub) column, 20 × 2.6 cm (GE Healthcare, Uppsala, Sweden) at a flow rate of 1 mL min−1. The column was washed with 60 mL sodium phosphate/ammonium sulfate (50 mM/0.92 M, pH 7.0) and was eluted using a gradient of 500 mL (0.92–0 M ammonium sulfate) at a flow rate of 2 mL min−1. The cytochrome c was eluted at approximately 0.37 M ammonium sulfate. Appropriate fractions were pooled and concentrated using an Amicon stirred cell 8050 with Ultrafiltration Membrane, MWCO 1000 Da (Millipore, Solna, Sweden). The concentrated sample was applied on to a Sephacryl S-200 Hiprep™ 16/60 column (GE Healthcare) and eluted using 0.1 M sodium phosphate, pH 7.0, with the flow rate of 0.1 mL min−1.
are shuttled from the periplasmic DMS dehydrogenase to the membrane-bound photosynthetic reaction center, mediated by the soluble cytochrome c2 (Creevey et al., 2008). In the present paper, we describe the purification and characterization of the cytochrome c discussed above. MS gives a molecular weight of about 9 kDa rather than AZD8055 manufacturer the 6 kDa found by SDS-PAGE. We denote this protein cytochrome c-Id1. Electron transfer to chlorate is thermodynamically feasible from its Navitoclax estimated redox potential, and we demonstrate its ability to serve as electron donor for purified chlorate reductase. Ideonella dechloratans was obtained from the Culture Collection of Göteborg University, Göteborg, Sweden. Cells were cultured anaerobically (8 L) and harvested by centrifugation at 8000 g for 15 min. Wet
Soluble proteins were extracted by Epothilone B (EPO906, Patupilone) centrifugation at 8000 g for 20 min and ammonium sulfate was added to the protein extract to 40% saturation. The solution was stirred on ice for 30 min, followed by centrifugation at 18 000 g for 10 min. Ammonium sulfate was added to the supernatant to 85% saturation and the solution was stirred on ice for 30 min. Precipitated proteins were pelleted by centrifugation at 18 000 g for 10 min, and resuspended in 10 mL sodium phosphate (50 mM, pH 7.0) containing ammonium sulfate (0.92 M). The solution was applied on to a Phenyl Sepharose 6 Fast Flow (low sub) column, 20 × 2.6 cm (GE Healthcare, Uppsala, Sweden) at a flow rate of 1 mL min−1. The column was washed with 60 mL sodium phosphate/ammonium sulfate (50 mM/0.92 M, pH 7.0) and was eluted using a gradient of 500 mL (0.92–0 M ammonium sulfate) at a flow rate of 2 mL min−1. The cytochrome c was eluted at approximately 0.37 M ammonium sulfate. Appropriate fractions were pooled and concentrated using an Amicon stirred cell 8050 with Ultrafiltration Membrane, MWCO 1000 Da (Millipore, Solna, Sweden). The concentrated sample was applied on to a Sephacryl S-200 Hiprep™ 16/60 column (GE Healthcare) and eluted using 0.1 M sodium phosphate, pH 7.0, with the flow rate of 0.1 mL min−1.
included physical examination and reco
included physical examination and recording of directly observed and spontaneously reported adverse events. Assessments performed at 12 months have been published previously in the 52-week follow-up study report [14]. Standardized ultrasonography was used to measure the total cutaneous thickness (epidermal, dermal and subcutaneous thickness) in the nasogenian BMS-777607 clinical trial area, which is located below the malar bone in front of the masseter muscle. The examinations were conducted by the same radiologist, using a scanner (Acuson-Siemens Sequoia 512; Siemens Medical Solutions, Mountainview, CA, USA) equipped with a 14-MHz linear array transducer. A large amount of acoustic coupling gel was used and the scanning was performed with minimal pressure. Four measurements were made from each nasogenian area and a mean value (right+left cheek)/2 was calculated at each visit. All the ultrasonographic examinations were recorded. A treatment responder was defined as a patient with a total cutaneous thickness >10 mm. Patient and physician satisfaction with treatment outcome was evaluated using the Global Aesthetic Improvement Scale [14] with scores from (1) very much improved to (5) worse. Self-satisfaction with facial appearance was recorded on a visual analogue scale (VAS) with scores from (0) not satisfied
selleck chemicals llc at all to (100) completely satisfied. Information about possible changes in patients' self-esteem after treatment with hyaluronic acid was captured using the Rosenberg self-esteem scale [16] and scores ranged from (0) low self-esteem to (60) high self-esteem. These tools are described in more detail in the 52-week follow-up
study report [14]. Related samples tests were used to compare values obtained at the first and subsequent visits: the Wilcoxon signed-rank test was used for continuous variables and the McNemar test for binary variables. The level of significance used was 5%. Results are Pregnenolone presented as mean ± standard deviation, unless otherwise stated. Twenty patients, one female and 19 male, were enrolled between September 2004 and April 2005 and are included in the study analysis. At baseline, the patients were 49 ± 7 years old and their mean weight was 74.7 ± 10.0 kg. Eighteen patients were Caucasian and two were of African descent. They had a long history of HIV infection; the mean duration from the first positive test was 13.6 years (minimum 8.5 and maximum 20.0 years), and the mean time on ART was 10.0 years (minimum 6.9 and maximum 15.6 years). All but one patient had been on stavudine (mean time on stavudine 40 ± 27 months) and 17 had stopped taking stavudine at least 1 year before inclusion. Details about the use of zidovudine were not included.
1 These two cases occur in the context of a changing epidemiology
1 These two cases occur in the context of a changing epidemiology LY2157299 of cutaneous leishmaniasis in Morocco itself, with an increasing distribution of disease throughout the country and the emergence of three coexisting species: Leishmania major, Leishmania tropica, and Leishmania infantum.2,3 This change is significant in a country
previously regarded as relatively low risk for travelers from the perspective of vector-borne infections (such as malaria and dengue). Returned travelers could have a valuable role as sentinels for changing prevalence of neglected diseases in endemic visited countries, particularly if local disease monitoring is suboptimal. p38 MAPK Kinase pathway These data become increasingly helpful when surveillance of infected travelers is undertaken in a systematic manner.4 Sodium stibogluconate and fluconazole were used to treat these two cases, reflecting the scant durable evidence available to guide therapy of OWCL, particularly in returned travelers. Pentavalent antimonial drugs (sodium stibogluconate or meglumine antimonate) are the traditionally accepted first-line agents.5,6 Although these agents can be injected intralesionally, patients with large or multiple lesions require parenteral administration, usually for 21 days, with attending
toxicities and demands on health care contact. Evidence for fluconazole in cutaneous L major infection is mixed.7 Miltefosine has recently emerged as an agent for the treatment of leishmaniasis, with the significant advantages of good oral bioavailability and tolerability. As yet, the evidence for miltefosine in OWCL is limited to a number of case reports and a single randomized, controlled trial for OWCL due to L major in
Iran.8,9 Efficacy varies between species. Identification of the Leishmania species infecting returned travelers by PCR is extremely useful. Species identification facilitates epidemiological study, which is particularly important if such investigation is difficult in the endemic country due to political instability or a lack of resources. It also contributes significantly to selection of the most appropriate treatment.8 With both cases presented here, the diagnosis of leishmaniasis was not considered Nabilone prior to the histological report, after the biopsy specimens were placed in formalin, thus reducing the yield of PCR techniques. This reinforces the importance of raising awareness of this neglected disease in nonendemic countries. The authors state they have no conflicts of interest to declare. "
"Background. There is an increasing number of imported cases of schistosomiasis in Europe, but there are only few studies on the efficacy of praziquantel for the treatment of schistosomiasis in non-endemic settings. Methods.
ictaluri were made in sterile water
As 1 μL of eluted sa
ictaluri were made in sterile water.
As 1 μL of eluted sample was run in qPCR, the amount of bacterial DNA in each milligram of tissue was equal to: bacterial DNA concentration (pg μL−1) × eluted volume/tissue weight (mg). Bacterial PI3K inhibitor DNA in each milligram of tissue was calculated as genome equivalents per milligram of tissue (GEs mg−1) based on the genome size of E. ictaluri = 3.8 fg cell−1 (Bilodeau et al., 2003). Data were analyzed with sas software (SAS, 1989). Percentages of theronts vectoring E. ictaluri were analyzed with Duncan's multiple range test of the general linear model (GLM) procedure. The correlation between the bacterial concentrations and numbers of theront carrying E. ictaluri or between bacterial concentrations used to treat theronts and numbers of fish positive for E. ictaluri was evaluated with Spearman correlation. Probabilities of
0.05 or less were considered statistically significant. Using flow cytometry, control theronts not exposed to E. ictaluri showed 6–8% fluorescing theronts, indicating low background autofluorescence (Table 1). Theronts exposed to E. ictaluri demonstrated significantly higher counts (P < 0.05) compared to control selleck kinase inhibitor theronts. Almost 60% of theronts exposed to E. ictaluri at 4 × 107 CFU mL−1 were fluorescent as compared to 42% exposed to 4 × 103 CFU mL−1 4 h postexposure to fluorescent E. ictaluri. There was a strong correlation between the E. ictaluri concentration and the number of fluorescing theronts (correlation coefficient = 0.75, P < 0.01). Theronts exposed to E. ictaluri for a longer duration (4 h) at all three concentrations also demonstrated a higher percentage of fluorescent theronts as compared to those exposed for 1 h. No fluorescent bacteria were observed on control tomonts (i.e. not exposed to E. ictaluri). All tomonts (100%) demonstrated fluorescent bacteria 2–8 h postexposure to E. ictaluri at 5 × 105 or 5 × 107 CFU mL−1 (Table 2). Tomonts exposed to E. ictaluri at 5 × 107 CFU mL−1 showed more bacteria than those exposed to E. ictaluri at 5 × 105 CFU mL−1 (Fig. 1). The bacterial number also increased from 2 to 8 h postexposure
(Fig. 1), suggesting bacterial replication. After 24 h, most tomonts divided into several hundred tomites and released infective Pyruvate dehydrogenase theronts. Among those theronts, 31.2% and 66.4% were observed to have fluorescent bacteria attached following tomont exposure to E. ictaluri at 5 × 105 CFU mL−1 or 5 × 107 CFU mL−1, respectively (Table 2). Theronts produced from tomonts exposed to E. ictaluri at 5 × 107 CFU mL−1 showed more fluorescent bacteria than those exposed to E. ictaluri at 5 × 105 CFU mL−1 (Fig. 1). Edwardsiella ictaluri survived and grew during the tomont division. Fluorescent bacteria were seen on tomonts and theronts collected at all sampling times (Fig. 1). The location of E. ictaluri was examined from z-series optical sections of tomonts 2 h postexposure to E.
e they occurred within the range of therapeutic doses), and 65%
e. they occurred within the range of therapeutic doses), and 65% were classified as intermediate reactions. The susceptibility factors associated most frequently with ADRs were comorbidities (i.e. the presence of diseases that were considered as risk factors to developing an ADR; 36%), age (26%) and exogenous factors Acalabrutinib in vivo (i.e. the presence of drug interactions that were involved in the occurrence of ADRs; 17%). Fifty per cent of the ADRs could have been prevented. Conclusions ADRs are very frequent in hospitalized patients and a significant
proportion of them is preventable. The DoTS classification allowed complete evaluation of the types of ADR encountered. We are currently carrying out a much larger prospective study. "
"The treatment of childhood cancer with chemotherapy, radiotherapy or surgery predisposes the child to a number of potential 'late effects', often complex and inter-related which may adversely influence growth, bone development and body composition or almost any endocrine gland function, depending on the treatment modality involved. As increasing time from cancer treatment is one of the risk factors for the development of endocrine dysfunction, effective long-term follow-up arrangements are necessary
for these patients to monitor for the development of such problems. Uncertainties remain about how services such as these should be organized and delivered in the longer term. "
"The prelims comprise: Half-Title click here Page Title Page Copyright Page Table of Contents Preface Numbers, conversions and tables "
"Hypocalcaemia and rickets may present relatively frequently in childhood.
A careful clinical and biochemical assessment of these cases should ensure that the relatively common causes are distinguished from rarer subtypes and treated appropriately. By contrast, hypercalcaemia is relatively rare and often resolves without ifenprodil therapy. Osteoporosis is associated with substantial morbidity, but bisphosphanate therapy is proving a highly effective therapy. "
"Hypoglycaemia may be due to reduced glucose availability or increased glucose consumption, and requires urgent investigation and management to avoid neurological damage and unnecessary diagnostic tests later. The majority of causes present in neonatal life and are transient in nature. However, severe and persistent hypoglycaemia may be a consequence of significant endocrine dysfunction or inborn errors of metabolism, and should be managed in conjunction with a specialist centre from an early stage. "
"All change in history, all advance, comes from nonconformity. If there had been no troublemakers, no dissenters, we should still be living in caves.' (AJP Taylor.) In the November/December 2010 issue of Practical Diabetes International, MEJ Lean's personal comment reported on 'How not to die from diabetes in a mountain hut'.
[1, 4, 15-20] Of the 62 reported cases, 12 (19%) patients died an
[1, 4, 15-20] Of the 62 reported cases, 12 (19%) patients died and 28 (45%) survived with sequelae. These reports are certainly not all the travel-associated JE cases that occurred during this period. However, the incidence of JE among persons from nonendemic countries traveling to
Asia is estimated to be less than one case per 1 million travelers.[1, 4, 21] The findings from this survey suggest that the low risk of travel-associated JE likely reflects an inherently low risk of virus exposure and disease for most US travelers rather than high rates of protection owing to vaccine-induced immunity. Despite the apparent low risk of JE virus exposure for travelers, JE is a severe but preventable BVD-523 nmr disease. All travelers to JE-endemic areas should be educated about personal protective measures to reduce the risks of vector-borne diseases. For travelers who will be in a high-risk setting based on season, location, duration, and activities, JE vaccine can further reduce the risk for JE virus infection.[1] Although a majority of travelers to JE-endemic countries surveyed indicated seeking travel health advice, only one third sought advice from a health care provider. Among those with higher JE risk itineraries, less than half visited a health care provider to prepare
for their trip, and people returning to their birth country were even less likely to see a health care provider. Travelers returning to their country of origin to visit friends and relatives are typically at greater risk than most tourists for travel-related infections but infrequently seek pre-travel health Selleck Epigenetics Compound Library advice.[15, 22, 23] These findings highlight the fact that clear and accurate information about travel-related health risks and prevention methods needs to be readily accessible to the lay public through various sources with possible targeted outreach to certain higher risk groups. This study was subject to several limitations. Although we attempted to obtain a representative sample of passengers to JE-endemic countries, our sample
population was not randomly selected from among all US resident travelers to JE-endemic countries. O-methylated flavonoid In addition, <60% of travelers on the selected flights were contacted to participate in the survey, and those who were not available might have differed from the travelers we were able to approach. More than half of those who were contacted were not eligible to participate, with language being the most common reason. Therefore, our data likely underrepresented US travelers for whom English is a second language, which may include a higher proportion of immigrants and persons returning to visit friends or relatives. We could not evaluate each traveler's itinerary in detail and some might have been misclassified with regard to JE risk and indication for vaccination.
aureus 8325-4 and DU 1090 were cultured in TSB at 37 °C to an opt
aureus 8325-4 and DU 1090 were cultured in TSB at 37 °C to an optical density at 600 nm of 0.5. Fifty-milliliter culture aliquots were centrifuged, click here washed with PBS, and resuspended in 1 mL PBS (2 × 108 CFU per 30 μL)
for histopathology experiments. For cytotoxicity studies, 5 mL of culture described above was resuspended in 10 mL of Dulbecco's modified Eagle's medium (DMEM; Invitrogen, CA). The minimal inhibitory concentrations (MICs) of apigenin for S. aureus were evaluated using the broth microdilution method according to CLSI guidelines (CLSI, 2005). Briefly, apigenin was diluted in a 96-well plate over the concentration range of 4-1024 μg mL−1 using double dilution method. Following inoculation with 5 × 105 CFU mL−1 of overnight broth cultures in each well, the plate was inoculated at 37 °C for 24 h. The MIC was defined as the lowest concentration at which the growth of S. aureus was inhibited. Staphylococcus aureus strain 8325-4 was cultured in TSB medium at 37 °C, shaken at 200 r.p.m. to an optical density (OD600 nm) of 0.3, and aliquoted into five 250-mL flasks in a volume of 100 mL. Apigenin dissolved in DMSO was added to the four cultures to obtain final concentrations of 1, 4, 16, and 64 μg mL−1. 1% DMSO was added to the control culture. The bacteria were cultured at 37 °C with constant shaking, and cell growth
was measured by reading the OD600 nm values every 30 min. Hemolytic activity was measured as described previously (Worlitzsch et al., 2001; Qiu et al., 2010a) using rabbit NVP-AUY922 purchase erythrocytes. Briefly, S. aureus cultures with different concentrations of apigenin were harvested when grown to the postexponential growth phase by centrifugation
(5500 g, 4 °C, 1 min), and the residual cells were removed using a 0.2-μm filter. A 0.1 mL volume of bacterial culture supernatants were brought up to 1 mL with the addition of PBS and 25 μL defibrinated rabbit erythrocytes for 30 min at 37 °C. The unlysed blood cells were removed by centrifugation (5500 g, room temperature, Interleukin-2 receptor 1 min). Following centrifugation, the hemolytic activity of the supernatants was detected by measuring the optical density at 543 nm. Medicine-free culture supernatant served as the 100% hemolysis control. The percent of hemolysis was calculated by comparison with the control culture supernatant. The culture supernatants collected previously were used in Western blot analysis. Samples were boiled with Laemmli sample buffer for 10 min, and then 25 μL of the sample was fractionated by SDS-PAGE (12% polyacrylamide gels; Laemmli, 1970). The Western blot protocol was performed as described previously (Qiu et al., 2010a, b). Proteins were transferred onto polyvinylidene fluoride membranes (Roche, Basel, Switzerland) using a semi-dry transfer cell (Bio-Rad, Munich, Germany). The membrane was blocked for 2 h with 5% bovine serum albumin (Amresco) at room temperature.
≥500 HIV-1 RNA copies/mL as a time-updated variable) CD4 cell co
≥500 HIV-1 RNA copies/mL as a time-updated variable). CD4 cell count was modelled in various ways, including the baseline, nadir and latest (time-updated) CD4 cell counts. Inclusion in the model of the time-updated CD4 cell count provided the best model fit. CD4 cell count was only available for 111 of 132 HIV-infected individuals with SAB. Five individuals who had their first CD4 cell count measured on the day of SAB diagnosis were excluded
from the analysis. HCV was not included in the model because of a strong correlation Maraviroc supplier between HCV and HIV transmission group (IDU). The multivariate analysis was performed in three ways. In the first analysis, each of the variables was adjusted for latest CD4 cell count only. In the second analysis, all the variables were adjusted for each other, with the exception of HIV RNA because of low numbers (HIV RNA was only available for 82 of the 132 HIV-infected individuals with SAB). In the last analysis, we stratified the data by transmission group to account for the interaction among variables. The significance level was set at P<0.05. sas statistical software 9.1 (SAS Institute Inc., Cary, Everolimus manufacturer NC, USA) was used for data analysis. The study was approved by the Danish Data Protection Agency (record no. 2007-41-1196). A total of 4871 HIV-infected and 92 116 HIV-uninfected
individuals were included in the study. HIV-infected individuals were predominantly male, Caucasian and infected through the MSM route. The baseline characteristics of the entire study population are shown in Table 1. A total of 329 SABs were observed, of which 45 were repetitive cases. There were 169 cases in HIV-infected individuals, of which 132 were first-time cases and 37 were repetitive cases. In HIV-uninfected individuals we observed 160 cases, of which 152 were first-time cases and eight were repetitive cases. The characteristics of the first-time SAB cases are shown in Table 2. Frequencies of methicillin-resistant
Staphylococcus aureus (MRSA) infection were low in both HIV-infected and non-HIV-infected individuals (0.7% and 1.3%, respectively) and no difference in 30-day mortality Tryptophan synthase was observed. The origin of the SAB was more often established for HIV-infected individuals, and CA SAB seemed to be more common in this group. Among HIV-infected individuals (Table 3), 50% of first-time SABs occurred in individuals reporting IDU as the HIV transmission route. IDUs were more frequently Caucasian and infected with HCV, tended to be younger at SAB diagnosis, had higher CD4 cell counts (at time of HIV diagnosis, nadir and latest prior to SAB diagnosis) and were less likely to have an AIDS diagnosis prior to the SAB diagnosis compared with other HIV transmission groups. Fewer IDUs received HAART and they were less likely to be virologically suppressed at the time of SAB diagnosis, but none of these differences reached statistical significance.
phosphorylase inhibitors
(PNG 8 KB) Additional file 2: Effect of complementation of the ep
Nanoscale Res Lett 2012, 7:310
Even conjugation times below
24 h might be sufficient for
: Enterotypes of the human gut microbiome Nature 2011, 473:174–1
Cytokine Growth Factor Rev 2000, 11:5–13 PubMedCrossRef 25 Wendt

redpajama_set_name: RedPajamaCommonCrawl


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Serbia – Kosovo: normalization but not recognition
Posted on October 2, 2012 by Editor	Leave a comment
02.10.2012 Branko Ilic , Serbian FBReporter
By Ian Bancroft
Tomislav Nikolic, President of Serbia
Before the UN General Assembly in New York began on September 25, Serbia's new president, Tomislav Nikolic, expressed Belgrade's readiness to engage in high-level negotiations with Pristina. Such political dialogue is expected to proceed during the autumn, to what end questions remain.
Thus far, Belgrade and Pristina have engaged in several rounds of negotiations on a range of technical issues – including freedom of movement, vehicle registration plates and the recognition of diplomas – under the EU's mediation.
Belgrade has been widely criticized for failing to implement several agreements reached, including those on Kosovo's participation in regional forums and integrated border management.
Some progress, however, has been made by Serbia's new government. A protocol on integrated border management has been signed, whilst the insistence that nameplates for Kosovo representatives in regional forums contain a status-neutral footnote has been dropped. Instead, the footnote need only be mentioned in accompanying documents.
President Nikolic has already stated his willingness to publicly shake hands with his counterpart in Kosovo, Atifete Jahjaga – a step his predecessor, Boris Tadic, was never prepared to take whilst in office (though he has since shaken hands with Kosovo's prime minister, Hashim Thaci).
Nikolic's nationalistic past potentially provides him with a firmer political foundation from which to deliver difficult compromises. However, the domestic consensus amongst Serbia's political elites that Nikolic craved is unlikely to materialise, partly because of the disarray in which the main opposition party – Tadic's Democratic Party (DS) – finds itself at present. The lack of a clear government strategy also hasn't helped.
Eager for a foreign policy success of her own, the EU's foreign policy chief, Catherine Ashton, is likely to play a more intensive role in the enhanced dialogue. During a meeting with Kosovan Prime Minister Hashim Thaci, Ashton remarked that 'difficult decisions would be needed both in Belgrade and Pristina, and both sides needed to be ready to engage, including at political level.'
The EU has made it clear that Serbia won't receive a date to commence accession talks until further progress has been made vis-à-vis Kosovo. As such, additional agreements are now expected, pertaining in particular to electricity transmission and telecommunications issues. Steps to remove so-called 'parallel institutions' in the north of Kosovo, which is predominantly ethnic Serb, will also be required.
Solutions to more substantive issues, however, particularly concerning the status of the north, remain distant. Serbia's prime minister, Ivica Dacic, recently called for the partitioning of Kosovo, describing it as the 'only possible realistic solution'.
The idea remains unpopular within international circles – and has been rejected out of hand in Pristina – partly because of fears that partitioning Kosovo would have negative ramifications elsewhere in the region, such as Bosnia-Herzegovina and Macedonia.
However, as James Ker-Lindsay, a senior research fellow on the politics of south east Europe at the London School of Economics (LSE), tells bne, "I still believe that a negotiated redrawing of the boundary between Kosovo and Serbia is the most logical solution to the Kosovo problem. There is nothing under international law that says that a state cannot negotiate its own boundaries. Indeed this is a fundamental sovereign right. If this is the price for a comprehensive settlement that will lead to Serbia's recognition of Kosovo, and Kosovo's full entry into the international system, then it certainly seems to be a price worth paying to draw a line under the problem."
Ker-Lindsay adds that, "if Kosovo really is unique, as we have so often been told, then surely any solution to that problem can also be presented as such. Moreover, Belgrade can simply say that its agreement with Kosovo is one that it reached in negotiations with Pristina. It has no bearing on how any other states in the region may wish to manage their own domestic affairs."
Kosovo's own domestic politics is set for a shake-up in the coming months, in part due to the expected return of Ramush Haradinaj, a former leader of the Kosovo Liberation Army (KLA) and former prime minister of Kosovo. Haradinaj is expected to be acquitted before the end of the year following a partial re-trial on six counts of murder, cruel treatment and torture. Haradinaj was originally acquitted in 2008 of a host of charges because of a lack of evidence, in a trial that was dogged by criticisms of witness intimidation.
Rumours are rife of a possible coalition between Haradinaj's Alliance for the Future of Kosovo (AAK) and Thaci's Democratic Party of Kosovo (DPK), with the former possibly serving as prime minister and the latter becoming president.
The possibility of early elections can also not be ruled out, which would provide the nationalistic Vetevendosje (Self-Determination) with an opportunity to build upon an impressive first election performance back in 2010. Vetevendosje has opposed dialogue with Serbia and advocated a Greater Albania platform.
Whilst relations between Belgrade and Pristina will likely continue to normalize in the coming months – barring any spike in tensions in the north of Kosovo – the more substantive issues of the north and recognition are likely to remain long unresolved. Those compromises achieved to date have been driven primarily by the prospect of European membership – a prospect that has since grown more distant. As the pace of accession slows, however, so too does the momentum towards further concession. While the doors of Europe remain open, a sustainable compromise agreement may still be possible in the future. Were they to close, however, the state of frozen conflict would ensue.
http://www.bne.eu/story4044


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I'm currently using Promise.any with a setTimeout function, but wondering if there is a built-in way to limit the amount of time this request takes? I.e. Timeout after 15 ms?
Promise.any([
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redpajama_set_name: RedPajamaStackExchange


text:
Antibody Discovery
Viral Neutralization
Cell Therapy Development
The Beacon® Optofluidic System
The Lightning™ Optofluidic System
The Culture Station™ System
Blog Posted 04.01.20
Everything You Need to Know About Coronavirus
SARS-CoV-2 emerged at the end of 2019 as a new virulent virus that causes coronavirus disease 2019 (COVID-19). Three months later we're still learning about it; however, the availability of advance technologies has increased the speed of research and therapeutic development. Health officials shared the full sequence of the virus after just one month, jump-starting studies looking for clues on how the virus behaves and can be neutralized, and therapeutic antibody and vaccine candidates are already preparing to enter initial clinical trials three months after we first learned of COVID-19.
So what do we know so far about the virus?
The structure and molecular mechanisms that drive infection
SARS-CoV-2 is spherical with protruding spikes. These spikes, aptly named Spike (S) proteins, interact with a protein on our cells called ACE-2 to enter and infect the cell1. The spike protein also needs to be primed by TMPRSS2, a serine protease, to facilitate fusion of the viral and host cell membrane.
Its closest relative: the SARS-CoV-1 from 2003
SARS-CoV-2 is also closely related to SARS-CoV-1, another coronavirus, that was responsible for the SARS outbreak in 2003. However, SARS-CoV-2 is about 10X more infectious compared to SARS-CoV and is spreading faster as a result2. The 2003 SARS outbreak lasted about eight months where there were a little over 8,000 cases with 774 deaths in total3. In comparison, there have been over 500,000 COVID-19 cases and over 20,000 deaths in just 3 months4.
How quickly it spreads
The SARS-CoV-2 spike protein has a higher affinity for the ACE-2 protein compared to the SARS-CoV-1 spike protein, making it easier to transmit from person-to-person. Also, coronavirus spike proteins consist of two halves that need to be separated before the virus can infect a host cell. This activation occurs more easily for SARS-CoV-2 due to the enzyme furin, which is found across many tissues in human cells.
A reason for optimism
The good news is that SARS-CoV-2 is not mutating at a high rate, which means that antibodies elicited by a vaccine will be broadly-neutralizing5. So getting SARS-CoV-2 vaccine will hopefully be more like getting a measles vaccine than a flu vaccine. Check out this article by John Cumbers on the timeline and 3 Paths To COVID-19 Treatment And Prevention – complete with infographic.
1. Hoffman M, et al. SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor, Cell. 2020.
2. Wrapp D, et al. Cryo-EM Structure of the 2019-nCoV Spike in the Perfusion Conformation, Science, 2020.
3. SARS Basics Fact Sheet. CDC. 2017. https://www.cdc.gov/sars/about/fs-sars.html
4. Coronavirus COVID-19 Global Cases by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University (JHU). John Hopkins University & Medicine. 2020. https://coronavirus.jhu.edu/map.html
5. Relatively Stable SARS-CoV-2 Genome is Good News for a Vaccine. The Scientist, 2020. https://www.the-scientist.com/news-opinion/relatively-stable-sars-cov-2-genome-is-good-news-for-a-vaccine-67319
Blog 04.20.20
Speeding the COVID-19 Drug Development Process
Collision from Home Panel Recap: Berkeley Lights CEO Dr. Eric Hobbs Talks COVID-19 Antibody Discovery
AstraZeneca enters Phase III clinical trials using antibodies found on the Berkeley Lights Beacon® system
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Sign Up To Get The Scoop | Vaseline®
The Healing Project
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Vaseline® Intensive Care™ Cocoa Radiant Lotion
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Skin Care Fundamentals
Take a (Very) Up-Close Look at Dry Skin and How Moisture Heals It
What is Healing Jelly, and What is It Used For?
Dry Itchy Skin Relief
Vitamin B3 for Skin
Your Questions About Vitamin B3 - Answered!
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Moisturizers containing Vitamin B3 are known to restore skin cells.
Still unsure? Check out a few of the most commonly asked questions regarding the use of Vitamin B3 and how Vaseline can help.
What is Vitamin B3?
Vitamin B3, commonly referred to as niacinamide, is made and used by your body to convert carbs, fats and proteins into energy, and known to help boost brain and digestive functions, improve arthritis, among other things; it's one of the eight B-complex vitamins.
The body can also produce niacin from the amino acid. Additionally, niacin comes in several forms, including niacinamide, which is known to have many skin care benefits.
What are good sources of Vitamin B3?
If ingested, the recommended daily amount of vitamin b3 niacinamides for adult males is 16 milligrams (mg) a day and for adult women—who aren't pregnant—14 mg a day.
So while you're making your grocery list, be sure to include foods like mushrooms, cereals, eggs, meat, green veggies, nuts and beans to get your intake. And keep in mind, while eating niacin-rich foods is important, topical application of lotions and products like Clinical Care Dark Spot Rescue Moisturizing Hand Cream, that contain Vitamin B3 have benefits, too. Which leads us to the next question….
What does Vitamin B3 do for your skin?
In its niacinamide form, the vitamin works to prevent water loss and retain skin's moisture content. It's also known to increase keratin. When it comes to aging skin, niacinamide improves the surface structure, helping smooth out skin's texture and reduce the look of wrinkles.
(arthritis) https://www.ncbi.nlm.nih.gov/pubmed/8841834
(arthristis) https://www.ncbi.nlm.nih.gov/pubmed/16848229
Improve skin function https://www.ncbi.nlm.nih.gov/pubmed/20354654
Eye side effects: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC505021/
https://medlineplus.gov/ency/article/002332.htm
https://www.mayoclinic.org/drugs-supplements-niacin/art-20364984
https://medical-dictionary.thefreedictionary.com/photocarcinogenesis
Vaseline® Clinical Care™ Aging Skin Dark Spot Rescue Hand Cream
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New Vaseline® Clinical Care™ Aging Skin Rescue Body Lotion is made with intensive moisturizers and hyaluronic acid boosters, to heal intense dryness.
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Ageing is inevitable, but fine lines and wrinkles can be prevented. Find out the best anti-aging skin care tips that are easy enough to follow for everyone.
Mature Skin Care
Mature skin tells a story. Make sure yours is told in the best light.
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Garbage removal vs dumpster rental in Odessa - Which is good for you?
For those who own a job you're going to undertake at home, you may be wondering if it is better to hire someone to come haul off all your rubbish and crap for you, or in the event you need to just rent a dumpster in Odessa and load it yourself.
Renting a container is a better alternative in the event you prefer the flexibility to load it on your own time and you also do not mind doing it yourself to save on labour. Dumpsters also work well in the event you've at least seven cubic yards or more of debris. Roll-offs usually begin at 10 cubic yards, so should you only have 3-4 yards of waste, you're paying for a lot more dumpster than you want.
Garbage or rubbish removal makes more sense if you prefer somebody else to load your old stuff. It also works well should you prefer it to be taken away quickly so it is out of your hair, or in the event you simply have a few big things; this is probably cheaper than renting an entire dumpster.
While roll off dumpsters are typically left on location, front load dumpsters will come pick up debris on a set schedule. This makes it possible for sanitation professionals to eliminate garbage and rubbish for multiple residences and companies in the region at affordable costs.
When you rent a dumpster in Odessa, you're dealing with professionals who use terms associated with the construction industry and dumpsters each day. Since you probably do not use these terms every single day, here's a bit of the lingo to get you acclimated. This can actually help you deal with business employees who may get impatient should you not understand what they're describing about their products.
"Container" and "roll off" are both acceptable terms for the large metal box you need to rent. Professionals don't use the term "dumpster" as much as the other terms. Containers are often rented in cubic yard sizes, but you don't have to include the "cubic" part. Simply say "yard" or "yarder." If, for instance, you wish to rent a 30-yard dumpster, you can say, "I'm interested in a 30-yard roll off" or "I Had like to rent a 30-yarder." Take advantage of these terms, and you will sound like a pro when you call.
You can put most kinds of debris into a dumpster rental in Odessa. There are, nevertheless, some exceptions. For instance, you cannot put compounds into a dumpster. That includes motor oil, paints, solvents, automotive fluids, pesticides, and cleaning agents. Electronics and batteries are also banned. If something introduces an environmental risk, you likely cannot place it in a dumpster. Get in touch with your rental company if you are unsure.
Certain kinds of okay debris, nevertheless, may require additional fees. In case you plan to throw away used tires, mattresses, or appliances, you should request the rental company whether you need to pay another fee. Adding these to your dumpster may cost anywhere from $25 to $100, depending on the thing.
When you rent a roll-off dumpster, you will be enticed to throw anything and everything inside. Common things which individuals generally dispose of in a dumpster contain solid waste material and most routine home and building waste, together with tree limbs and landscaping debris. They could also be utilized for company and commercial cleanouts, house renovations, getting rid of junk when you are moving to another dwelling, bigger landscaping occupations and much more.
A record of things you CAn't set in a roll-off dumpster contains paints and solvents, automotive fluids, pesticides, chemicals, electronics and batteries. If you attempt to include these things, you'll likely end up with an additional fee. Other things which will definitely incur an additional fee include tires, mattresses and appliances. Additional heavy substances are also not allowed; things that are too hefty may exceed authorities transportation regulations and be dangerous to haul.
One of the largest concerns you probably have when renting a dumpster in Odessa is how much it will cost. Among the most effective approaches to negate this anxiety would be to get precise advice. When you call to get a price quote, have a good idea of just how much waste you will need to remove so you may get the most effective recommendation on dumpster size. In case you are unsure on the total amount of waste, renting a size larger will save you the added expense of renting another dumpster if the first proves overly small.
Supply any information you think is important to ensure you do not end up paying for services that you do not really want. More than a few companies charge by the container size, while others charge by weight. Make sure you know which is which so you've a clear quote. Likewise, make sure to request whether the quote you receive includes landfill coststhis is going to keep you from being surprised by an additional fee after.
Planning ahead for your dumpster rental in Odessa will make your project easier and safer to finish on time. When renting a dumpster in Odessa, follow these tips to help you plan ahead.
What if I want my dumpster in Odessa picked up early?
When you make arrangements to rent a dumpster in Odessa, part of your rental agreement contains a stated length of time you are permitted to use the container. You usually base this time on the length of time you think your project might take. The bigger the job, the the more time you will need the dumpster. Most dumpster rental companies in Odessa give you a speed for a particular amount of days. Should you surpass that quantity of days, you will pay an extra fee per day. If the job goes more quickly than expected, maybe you are ended with the dumpster earlier than you anticipated.
If that is true, give the dumpster business a call and they'll probably come pick your container up early; this will allow them to rent it to someone else more quickly. You normally will not get a reduction on your own rate if you ask for early pick up. Your rental fee includes 7 days (or whatever your term is), whether you use them all or not.


In Chondigor village, Northern Bangladesh, Habitat for Humanity's four year CS WASH project is drawing to a close. One success story from the project is that of Nayan Mia, a local sanitation supplier, who through the project has gone from the uncertainty of life as a casual farm labourer to running his own successful sanitation business.
Nayan received training which was focused on increasing the skills of sanitation suppliers, and supporting them to develop higher quality latrine products. The project in turn worked to generate demand for improved sanitary latrines through awareness raising and providing access to finance through the creation of a revolving sanitation loan fund. Almost four years after receiving that first training, Nayan's business is successful and employs two other workers. Prospects for Nayan's business seem good, and they recently received an order for 200 latrines from the local government.
Nayan says he is proud about what he has achieved: "This business not only gives me profit but also helps people, and I am happy to help the people."


We are a team that aims to empower the elderly community through design and crafts! Because age does not matter only people and their stories. With over 60 grannies We Will Rule The World!
We work to empower the elderly community and we're running a workshop program called "A Avó Veio Trabalhar", dedicated to people over 60 where they can find again a regular work, learn and practice crafts such as sewing, crochet, screen printing and weaving, with the aim of producing four annual collections and workshops oh home-wear.
This is a social impact experience 󶀁 where 100% of what you pay for this experience goes to Fermenta .
Dive into our grandma's stories and help us with the craft making workshop. Sit next to the nicest grannies in town you'll have the opportunity to chat with them and learn from them how to creative embroider a black and white postcard of Lisbon. You'll see their current jobs and you'll get astonished by how much they have to share and how they where involved in Lisbon history.


A mobile device, with sufficient battery and powerful wifi, that's enough to bring us a wonderful world of unlimited information and pleasure. We are all living in the mobile world. How to beautify this world toward optimized user experience? How to present clear UI and UX on a limited screen without overload? Many elements should concern, and I bet mobile typography is an important one.
Mobile design requires highly details and elaboration. Every elements chose on this one small screen should be of both aesthetics and functionality. It's quite challenging to make mobile typography work for your users just right. But there is actually a practical way to follow, this article describes essential practices of typography in mobile design.
As a designer or even a developer, some may have never been usually trained or learnt about typography. This is not a good thing. You don't have to but you really should.
In short, typography involves everything related to the written language on a screen, and requires both the art and technique skills of designer.
2. Why typography matters in mobile design?
Not a single screen can get rid of copy completely. Likewise, by displaying copy elements on an interface disorderly can not reach effective UI and positive UX. Although images and video are dynamic and colorful, users still need to gain information through text. It's more than a habit, also text can convey things other elements can't do. A good designer should do good mobile typography design to ease user's eye and make the interaction more productive.
Second, what are the best practices in mobile typography?
Normally, mobile typography consists but not limited of the following elements. A note first: mobile design is changing, similarly, mobile typography can't be unalterable. We pay respect to the existing rules, still, be creative.
1) Increased text sizes and weights: help with readability throughout the system.
2) Offers a range of larger type sizes—in addition to standard dynamic type sizes—for users with accessibility needs.
So, what elements worth paying attention?
Fonts selection is not treated right, either been neglected, or simply adopted from the library. Actually, different type of content requires different font, because font can express feelings. Image use thick fonts with hard edges for feminine copy, quite weird, right? Instead, you should choose curvier and thinner fonts.
On the other hand, over-decorative fonts may look illegible on small screen. Maintain a simple and clean UI and use fonts of that style is the key. You may choose a secondary font to make contrast with the primary one. In that case, 2 or 3 fonts is quite enough.
You may need the details. Here is a collection of amazing fonts and typesetting rules.
Mobile screen is limited, so the font size matters a lot. If you simply use tiny font on a mobile screen, that's funny. Although users can pinch or room to see the text, it's not an excuse. Smaller text may hurt user's eye and takes more time to read, while bigger text may use up the screen quickly and break in the reading coherence.
Then which one is appropriate? For iOS, use text size that's at least 11 points, while for Android, choose 14 sp for main text. Do notice this is mostly used criterion in main copy, not changeless one. Moreover, you may think to use type that is slightly bigger than usually on a desktop screen.
Use a single typeface and a few font variants and sizes. Mixing several different typefaces can make your app seem fragmented and sloppy. highly legible at both small and large sizes. A brand or an app, usually have it's own default font. Apple uses San Francisco, Nokia use Nokia Pure and Google Android uses Roboto.
Apple choose font according to the product feature. For example, use Myriad(Pro) Light for iOS 7, SF-UI in iOS 9. In iOS 10, the San Francisco variants were SF UI Text and SF UI Display.
For more, check the iPhone X UI deisgn.
Use built-in text styles whenever possible. The built-in text styles let you express content in ways that are visually distinct, while retaining optimal legibility. These styles are based on the system fonts and allow you to take advantage of key typographic features, such as Dynamic Type, which automatically adjusts tracking and leading for every font size.
Leading is the space between lines. Mobile screen is smaller, so leading is usually smaller than a desktop version. When set leading, tighten it for mobile screens than on desktop. Wider or shorter leading are both ruins the mobile UI. Many believe 1.4em is the standard leading, but still, it's a little bit shorter, users may have a feeling that the text is tighten up. In design, the standard leading should be 120% the point size of the font. Another common used tip: short line length requires less leading.
Line length is also the measure in mobile typography. The length of a text line can impact the whole typography. Line length of a desktop screen will go beyond the mobile screen borders. In mobile typography, the amount of characters on each line, font size and line length are closely connected. They work for each other harmoniously is the key to readability. Keep the number of character per line within 30-40 is a good choice.
Space is like in everywhere in design. Space can bring the feeling of freedom and relaxing. Space in mobile typography mainly contains: space between lines, space in the margins, paragraph space. Proper space in mobile typography can help user better interact with the text. Designers can consider to start in the 10 to 20 percent range. Do not make the area of space too much for the mobile screen is not large, or you are waste the room.
Hierarchy is to emphasize the key cope elements from the whole text and also create contrast. But hierarchy in mobile typography is thinner than a web interface, which normally owns 3 levels. Mobile screens have a more limited space, so many designers apply only 2 levels. A headline and a body is enough, headlines is to grab the reader instantly and the body toward readability. This is also a tendency of mobile design. This can make the mobile UI clean and still maintain contrast and hierarchy.
On mobile screen, the copy is less than web face, as a result, the contrast becomes exaggerated. The biggest rule is to weaken the contrast. If you use ambient light, and short fonts on small screen, you are not helping but bring a headache to your user. Color choose can make powerful contrast, what's worse, red text with green background. On the other hand, using right color can make your UI interface looks perfect. Moreover, font size is another big consideration of contrast. Just do not go too far when set hierarchy, the font size of headline can not be too big than the body. The proportion of the space and the body can also cause tiny contrast.
Kerning is the spacing of two letter. It is a quite tiny factor in mobile typography but worth attention. Yes, in a large copy block, kerning may not seem as a problem. If you've been very careful, you may notice that sometimes the kerning between a capital letter may resulting in inconsistent letter spacing compared to the spacing between lowercase letter. Pay attention to this problem and keep the space visually consistent.
11. Tracking - the letter spacing applied to all characters in the font.
Since I mentioned kerning, it's necessary to involving in tracking. The two term may cause confuse to designers, similar but different indeed. Tracking is the letter spacing of all characters.
Effective tracking makes text more readable. Usually, font usage can adjust tracking appropriately, so you don't need to adjust tracking often. And Larger copy block requires less tracking, and smaller one requires more tracking.
Normally, text can be placed 4 ways: left, right, center or justified. Which one is better in mobile typography?
The key is to keep a comfortable and clear rag. The former 3 ways can all leave a rag, while the justified have no rag on either side. Moreover, Justified text results in inconsistent whitespace, and in the worst cases leads to a couple of words on a line. So justified text can first be removed from mobile typography.
Left side alignment is the best choice of the rest 3. It can resulting in a ragged right edge, which allows user's eyes jump from one end of a line to the next consistently. However, some claim that a mixing alignment can work better. The copy is a large block, use left side alignment; while for the title or short lines, centered looks good.
Keep a balanced UI is not enough, the functionality is equal important. Make it actually work can do better UX. On a mobile, we usually have some actions like purchasing products, make a order or book a ticket. Make sure users know what it will do next and they can easily do the actions. Functional typography should be highlighted among the other and clickable elements should be big enough to tap on them. Keep the usability first.
Mobile device have various size. Responsive design also have already applied to mobile design. Responsive typography becomes a great factor in this trend. It's just not something simply about breakpoint. Any wrong usage of the whole above elements can ruin the overall mobile UI design. It's requirement for designers to consider how mobile typography will look on different devices.
Typography is important in all kinds of designs, so as in prototype design. Excellent mobile typography can work together with all other UI elements towards a clean and productive mobile UI. but in mobile prototype design, text don't need to be meaningful. For example, in Mockplus, one of the professional prototyping tool, you can use text component to design with simple drag-and-drop. Mockplus contains single single-line text and multi-line text component. You can freely to define the properties of the text, like color, font, font size, alignment, etc. Beside, the auto data fill function of text can save you much time. What's best is you can test the design on a real mobile to check if it's of great readability.
The above are mainly covering all elements concerning mobile typography skills. Keep in mind the rules and guides are a good help, but do not forget to pay attention to the new trend. Typography will definitely gain more weight in 2018, Stephen Perry once claimed 2017 would filled with bold typography, and that's true. In 2018, you may prepare to embrace minimalistic. Let's see.


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.... The ability to understand and share the feelings of another.
I am reading the beautiful memoir, In Shock, by Dr Rana Awdish. It is her story of falling desperately ill and how the hospital treatment she received taught her to become a better doctor by developing empathy for patients. It's beautifully written and a powerful message.
However, I found myself bewildered at times by various things she struggled with. During her first surgery, she heard one of the doctors say, "We're losing her," and she was horrified and offended that they said it. Try as I might, I can't stir an understanding of why. If I heard those words, I would be terrified of course that I was dying, but I'd also know that someone recognised the situation, cared about it, and was determined to fight for my survival. Similarly, while Dr Adwish was disgusted that a doctor told his colleagues during morning rounds that "she's been trying to die on us," I personally would have have felt warmed by it. Rather than thinking the doctor was seeing me as an adversary, I'd have looked past his phrasing and felt seen, valued, and that the hospital staff were focussed on winning the battle to save me.
For a while I wondered if there was something defective in me that made me see caring where Dr Awdish saw inhumanity. But I reminded myself that empathy doesn't look or feel the same for everyone. My personal life history and the culture I live in makes me inclined to sense caring within blunt language and apparent detachment.
For example, when I was seventeen, I was in an accident that almost killed me, rendered me unconscious for days, and left me looking severely wrecked. On my second morning of consciousness, awake but drifting in hazy half-dreams, I was roused by a doctor lightly kicking my bed. Some people were horrified to hear he did this. To me, alone and scared in a hospital room, confused, in pain, sure that I looked like a monster, his kicking the bed felt friendly. It felt like he understood my misery and was able to reassure me with one simple gesture that he wasn't worried about me, nor disturbed by how I looked.
I also know empathy and good manners present quite differently in other cultures. And as we understand more about neurodiversity, we are learning that some people experience empathy by different processes than we are typically used to. There's also the fact that how a person expresses themselves is not always indicative of how they feel. For example, a woman can be so highly empathic that she is overwhelmed and shuts down, thereby seeming disconnected and uncaring.
I actually believe empathy is overrated. We can't always understand what someone else is feeling, even if we want to. And it's just as easy to be good to someone even if you don't resonate with their emotions. I rate kindness above empathy. I also rate higher the simplicity of listening to each other. Tell me how you feel. I might not empathise, but I can have the decency to allow you your feelings and care for you in ways you actually find helpful. I can also tell you why I talk to you the way I do, how I feel, what I bring to the relationship, and I hope you will be willing to listen and value my perspective even if it's not what you yourself feel. Together we can communicate and come to harmony without having any empathy at all.
These thoughts about empathy were sparked by but aren't in response to Dr Awdish's book. It's a gripping recount, thought-provoking, gorgeously written, and I highly recommend it.
it's a very interesting question for me, pondering whether kindness is more important than empathy... i do understand why you say this, and in some ways i agree: one shouldn't have to empathise with someone in order to wish them well and behave decently toward them. but it's kind of a chicken and egg question for me... does the ability (in however basic and limited a fashion) to feel/imagine what others are feeling evoke kindness, or does kindness (a willingness to be decent or beyond decent to others) evoke compassion? maybe both are operative; some people may not be very empathetic, but are kind by nature or by teaching, whilst others' kindness stems from their empathy? perhaps empathy is something inborn, like having brown eyes or a tendency to freckles, whilst kindness is something learned?
any way it turns out, both empathy and kindness seem sorely lacking these days... too much media amplification of the ugliness, too few children reared with genuine connection, too much fear. which only points up the need for a no-empathy-required emphasis on kindness such as you describe.
I agree with you that kindness is more important than empathy. Kindness is not a feeling and should not be contingent upon whether one 'feels' for another or not, it is a moral obligation (although, we're not allowed to use the 'M' word anymore, are we?).


Getting your first piece of work right on the cover is always awesome!
Big anatomy – not out of proportion, but the kind that fills up a panel and puts people in dynamic positions. Especially people charging towards the reader at high speed!
BANG AGAIN! EVEN MORE IN YOUR FACE!
Action and drama – the kind of pacing and pose selection that got him plenty of gigs in the world of American superheroes for many years.
Beautiful action choreography, and I do love an artist who draws in background sound effects.
There's also no getting around the fact that, for the early days at least, Hairsine's work was notable for looking kinda a lot like early McMahon. Don't get me wrong, it's powerful stuff, but the comparison is, well, notable.
Trevor Hairsine got his break in 2000AD introducing a whole new character, indeed the cover star twice in her opening series: Harmony. I'll get back to her later. Rather rapidly after that, Hairsine became something of a star Dredd artist, for example drawing the Megazine episodes of Dredd epic Wilderlands, and then immediately delivering new serial Three Amigos, designed to be a classic story that would draw in new readers with the relaunched Megazine volume 3, itself timed to coincide with the enormous popularity of the 1995 film Judge Dredd (except it ran a tiny bit late).
So, the Mick McMahon thing. Not only was Hairsine using that look for his Dredd work, his very first gig on the Megazine came through exactly in time with McMahon's own triumphant return to Judge Dredd for the first time in decades with Howler.
It's a little as if editor David Bishop knew people would be scratching their heads at mid-90s McMahon, perhaps expecting him to draw in the same way he did back in 1981. And to temper that reaction, he found a McMahon-ish artist to draw for the magazine.
I mean, if you've been asked to recapture the spirit of classic Dredd epic the Cursed Earth, you can't ask for better!
As it is, Howler came in for a bit of a kicking on its initial run (as I recall from the letters pages, anyway), but is now seen as something of a classic Dredd tale. Hairsine meanwhile found instant popularity – as he deserved! – although time has been a little less kind to the stories he drew, with Wilderlands and Three Amigos both seen as lesser Dredd.
Dig those McMahon-style giant boots! Also the classic 'hunched' pose, the better to fit into a small panel.
Atmospheric action with a spooky bent.
Crucially, Hairsine is not and never was a McMahon clone – it's more that, for a specific gig, he chose to draw in McMahon's style, (much like McMahon himself was once explicitly attempting to ape Ezquerra). As you can see pretty clearly by going back to the beginning, he has his own thing going. Check out Harmony: Blood & Snow.
This style, to me, is a) it's own thing, and b) VERY much of the mid-90s. It's both sketchy and detailed, cartoony and serious, with hard action, visible sound effects and motion lines, and combining that action with both horror and comedy. It's actually quite a lot more Simon Bisley than Mick McMahon, if you want to make artist comparisons.
Look, Hairsine has even drawn Mr Bisley into this page!
That's him with the sunglasses, yes? And in general, the goofy bystanders and background comedy is, for me, an example of the sort of Viz-esque / grown-up Beano look of 1990s funny stuff as popularised by the Biz (not to mention Jamie Hewlett).
Of course, Hairsine is also just meeting the script head on. For my money, Harmony as a series got more interesting when she left the wilderness and went back to the city (when the series rotated between other artists), but Hairsine remains the most accomplished comics creator to work on the strip, wild and weird as his opening series was. I mean Blood and Snow is sort of a bounty hunter thriller with a revenge plot going on, but then it turns into a 'The Thing' riff, only set in a Benny-Hillish nudist colony instead of a spooky research station. The shifting tones ought to be super weird, but somehow Hairsine (and writer Chris Standley, of course) keep it amazingly consistent, with the humour setting at sardonic meets deadpan meets 'expectation of OTT action at any moment'. In other words, totally 2000AD.
Where the heck did a scary alien monster come from in this tale of Bounty Hunters?
It did get a bit bogged down in having too many characters, and to my mind it was a shame that the villain, Havoc, had a more consistent and indeed simplistic design than Harmony herself. It's kind of a rule that in the first series with a brand new character, you need to show your hero front and centre as many times as you can, ideally with the same hairstyle/clothing/weaponry, so that readers will get to know her. Sadly the requirements of costume and setting changes in this story made that impossible.
Can't remember if Havoc is a mutant, an alien, or just a dude with a squished nose, but he's a classic 2000AD antagonist.
He's a great fit for this kind of setting, adding some humour to a dour situation simply through facial expressions.
and then joining a large team on weekly Dredd, with a bit of Anderson, Psi thrown in. This time he's doing it his own way, bringing back a lot of the 1990s cartoony but sort of realistic action vibe, and dialling back the McMahon stuff.
Still going strong with the full-figure posing. This one captures Dredd's supreme confidence so well!
It's not all Judge Dredd – he had a go at a Sinister-only episode of Downlode Tales, and tackled the first half of book II of Mercy Heights. For my money, his episodes are on a par with Kevin Walker's work on the original, and It's arguable that the space hospital saga would have fared better had Hairsine been able to complete the whole thing – or possibly if writer John Tomlinson had been able to structure his soap opera so that different episodes focussed on different characters, thus not requiring each artist to draw each person, and indeed each setting, entirely consistently.
Enough deliberating, let's bask in some Hairsine storytelling goodness, eh?
More epic sound effects, this time drenched in blood!
but I don't know it. Looks cool, though, and it kind of functions as an invisible panel border. Neat.
Hairsine's more painterish style for this one.
If you don;t find this kind of thing funny, I wouldn't recommend Judge Dredd.
Is there a hint of Alan Davis in there, or is it just me?
The loneliness of Finnigan Sinister.
To an extent, Hairsine suffered from never really having a crack at a great 2000AD series. Some of his shorter Dredds are pretty fun – the final Taxidermist outing, the hilarious tale of Chairman Dilbert – but nothing to rival the top tier of 2000AD, which means I sometimes think he's not that well remembered amongst the pantheon of 2000AD art legends. And none of that's his fault, 'cos he's damn good.
He kept in touch over the years with some cracking covers, before disappearing into the American comics fold.
Much, much later, Hairsine has turned in a few more pages on Dredd, scripted by his old Cla$$war buddy, Rob Williams. As you'd expect, his style has evolved quite a bit; it's lost that kinda scratchy, thick-lined look he used to use. You could even say that the McMahon influence has morphed more into a Bolland-look, to pick an artist whose style couldn't be further removed! But the dependable action beats are very much still intact, and it'll be a treat if we get some more in the future. Who knows?
that still retains some of that Blood & Snow feel.
Hairsine still delivers the posing goods, and those 'pushing limbs out of the panel and into your face' perspective tricks.
If you're fixing for more Hairsine, I'd recommend his most recent work with Valiant comics, which is kind of a half-way point between superhero comics and 2000AD*. High concept, high-octane action with a thick seam of cynicism, sarcasm and plenty of high-cultural references (and some pop culture, too). That said, I could stand to see more Hairsine in the Prog for sure!
There's surprisingly little on the internet – his own website seems to be out of service, and I can't find any interviews!
and this brace of monsteriffic covers!
The Get Sin pages are Hairsine under Barry Kitson inks, I think. Which explains the Bolland.
Hairsine's art on Skulls (1836) featured inking much closer to his own aesthetic.


text: Wendy Hinshaw is an Associate Professor and Director of Writing Programs in the English Department at Florida Atlantic University. Her teaching and research integrate community engagement, public rhetoric and social justice, and her current work investigates how prisoner art and writing shapes and is shaped by the historical, institutional and cultural contexts in which it circulates. She has collaborated with Kathie Klarreich to develop best practices for facilitating writing partnerships between prison and university classrooms, and their work appears in Women, Writing and Prison (Rowman & Littlefield 2014). Her work also appears in the collections Practicing Research in Writing Studies and Silence and Listening as Rhetorical Acts, and in journals including Feminist Formations, JAC, and Transformations.


"Thailand Cost of living Stats, NationMaster." 2013-2014. <http://www.nationmaster.com/country-info/profiles/Thailand/Cost-of-living>.
"Thailand Cost of living Stats", NationMaster [Internet]. 2013-2014. Avaliable from: <http://www.nationmaster.com/country-info/profiles/Thailand/Cost-of-living>.
"Thailand Cost of living Stats", NationMaster. Avaliable at: nationmaster.com. Assessed 2013-2014.


text:
Gundam: Hathaway Producer: 2nd Film May Not Open Before 2024
posted on 2021-12-03 16:00 EST by Alex Mateo
Film's next stage is Australia
Shukou Murase , the director of the Mobile Suit Gundam Hathaway ( Kidō Senshi Gundam : Senkō no Hathaway ) anime project teased during the first film's 4K UHD Blu-ray Disc release event on Thursday that the second film may not open before 2024, the year of the next Summer Olympic Games, at least. The film's producer Naohiro Ogata revealed that the next stage of the film series is Australia, but it has been difficult to cover the area because of the new coronavirus disease (COVID-19), so the director has been using a flight simulator to fly around the sky there.
The film project will be a trilogy, and the second part has a working title of Kidō Senshi Gundam : Senkō no Hathaway: San of Bright . The film's producer Ogata elaborated that the Japanese katakana characters "San" (サン) can be read as "sun" or "son." The film's main character Hathaway Noa is the son of the character Bright Noa. Ogata stated the second part will have some differences from Yoshiyuki Tomino 's original novel series.
The film is the first Gundam film since 1988's Mobile Suit Gundam: Char's Counterattack to top the 1 billion yen mark. The film has earned a cumulative total of 2,209,628,200 yen (about US$19.57 million) in the Japanese box office as of October 10.
The film sold 259,074 tickets for 523,943,800 yen (about US$4.77 million) in its first three days at the box office. It ranked at #3 (in terms of tickets sold) in its opening weekend.
The film opened in Japan on June 11, after previously being delayed three times. The movie was originally slated to open in Japan in July 2020, but was delayed due to COVID-19. The film was delayed in April from May 7 to May 21, and was then delayed again due to the extended state of emergency declared in Japan.
Netflix U.S. began exclusively streaming the film on July 1.
Source: Mainichi Shimbun's Mantan Web