text:
Home| Contact Us| Visit Us
Li Ka Shing Knowledge Institute
Keenan Research Centre for Biomedical Science
Research Leadership
2018 St. Michael's Research Report
MAP Centre for Urban Health Solutions
The HUB Health Research Solutions
Evaluation Centre for Complex Health Interventions
Centre for Global Health Research
Musculoskeletal Research Program
Interprofessional Practice Based Research
(IPBR)
Collaborative Specialization in Resuscitation Science (CSRS)
Critical Illness and Injury Research Centre
Neuroscience Research Program
Cardiovascular Disease & Diabetes Research Program
Biomedical Zone
Medical Imaging Office of Research & Innovation
LKS-CHART
Centre for Depression & Suicide Studies
Students & Trainees
Research Training Centre (RTC)
Keenan Research Summer Student (KRSS)
Undergraduate & Medical Students
St. Michael's Hospital Research Student Association
Staff Services
Patient Engagement Resources
Research Employment
Research Intellectual Property
U of T Library Card Access
Library Research & Resource Workshops
Research Training Centre / Research Training Centre-Finances
Writing an Abstract ›
Funding Databases ›
U of T Funding ›
Use Pivot to find funding
Securing adequate funding is an important part of research and academic development. There are many funding opportunities available to SMH trainees, including internal, university, government and non-government opportunities. Students should always consult with their university regarding opportunities and application deadlines.
SMH Internal Scholarships and Awards
SMH RTC Scholarship
RTC Travel Award
External Funding Opportunities
Opportunities for trainees are updated weekly in our Current Funding page for Trainees as well as on our biweekly newsletter the RTC Express. To be on the mailing list for the RTC Express, please contact rtc@smh.ca.
Tri-Council upcoming funding opportunities
CIHR
NSERC
SSHRC
Banting Postdoctoral Fellowship
The Banting Postdoctoral Fellowship Program is intended to attract and retain top-tier postdoctoral talent. This is a very competitive award, with 70 fellowships awarded each year across Canada; each institution is asked to put forward only their top candidates.
Value & duration:
$70,000 per year (taxable)
2 years (non-renewable)
Ontario Graduate Scholarship (OGS) Program
The Ontario Graduate Scholarship (OGS) Program recognizes academic excellence in graduate studies at the Master's and doctoral levels in all disciplines of academic study
$5,000 per session for 2 or 3 consecutive sessions
See university department for specific deadlines
Mitacs funding opportunities
Accelerate: internships for graduate students, postdoctoral fellows, rolling deadline
Elevate: internships for postdoctoral fellows, next call opens in May 2018
Globalink: travel funding between Canada and several international partners, rolling deadline
Canadian Science Policy Fellowship: usually opens in January
Check the St. Michael's Hospital Research Funding Database regularly for updated funding opportunities:
University funding opportunities
Students who are pursuing research-based master's or doctoral studies may also qualify for additional financial support, which are administered by the respective graduate units. Please check with your specific department, and also visit the Graduate Awards Office for additional information about scholarship and financial aid programs.
*Please ensure to verify all internal application deadlines with your university and/or program
Amount & Duration
AACR-Ocular Melanoma Foundation Fellowship, in Honor of Robert C. Allen, MD The AACR-Ocular Melanoma Foundation Career Development Award represents a joint effort to encourage and support junior faculty to conduct ocular/uveal melanoma research and establish a successful career path in ophthalmology, ocular oncology, uveal melanoma biology, or a similar field. Eligibility is limited to junior faculty who, at the start of the grant term, will have completed their most recent doctoral degree or medical residency within the past 11 years. The research proposed for funding must be translational or clinical in nature and must have direct applicability and relevance to ocular/uveal melanoma. Post Doctoral Fellow Upper $50,000 USD for 1 year January 16, 2020
endMS SPRINT - endMS Scholar Program for Researchers IN Training (SPRINT) The endMS Scholar Program for Researchers IN Training (SPRINT) is a national training program aimed to enhance knowledge and skills related to MS research among trainees and increase opportunities to conduct MS research in Canada. Post Doctoral Fellow $2,500 CAD for 13 months January 27, 2020
Dick Martin Scholarship Award
This national scholarship is available to students undertaking an occupational health and safety related course or program leading to an occupational health and safety certificate, diploma or degree at an accredited college or university in Canada. MSc, PhD $3,000 CAD for 1 year January 31, 2020
Mensa Canada Scholarship Programme
Mensa Canada invites applications for its general scholarship program. This enables students to pursue their career goals. MSc, PhD, Postdoctoral Fellows, Undergraduate students $2,000 - $3,000 for 1 year January 31, 2020
The Edgar Kerstan Memorial Scholarship
Mensa Canada invites applications for the Edgar Kerstan memorial scholarship. This supports Canadian citizens or landed immigrants enrolled in a full-time program at a Canadian post-secondary institution. MSc, PhD, Postdoctoral Fellows, Undergraduate students Upper $3,000 for 1 year January 31, 2020
Student Research Fellowship
Each fellowship consists of a $3,000 award and a two-year complimentary subscription to the Journal of Vascular Surgery. The award is designed for students to spend a meaningful period of time on a project either in a block of several months or spread out over a longer period of time, not to exceed 12 months. The minimum full-time commitment is two months. Undergraduate. MSc, PhD, Postdoctoral Fellow $3,000 USD for 1 year February 1, 2020
Colgate Palmolive Fellowship in Nutrition, Oral Health/Dental Education
This grant is given to support research in nutrition and oral health or dental education by doctoral students seeking a doctorate in nutrition and oral health or dental education, Masters thesis research on nutrition and oral health/disease or RDNs with advanced degrees doing research in the area of nutrition and oral health. PhD $15,000 USD for 1 year February 1, 2020
The Cooley's Anemia Foundation invites national and international clinical and basic science investigators (postdoctoral or junior faculty) to apply for its prestigious fellowship program. Applications should be focused on the understanding or treatment of thalassemia or a complication that is related to thalassemia. The areas of interest include, but are not limited to, studies of globin gene regulation, globin gene transfer and expression, fetal hemoglobin production, hematopoietic stem cell research, bone marrow transplantation, iron chelation and iron overload, endocrine and cardiac disorders in thalassemia, and transfusion therapy and its complications. Postdoctoral Fellows $50,000 USD for 1 year (renewable) February 3, 2020
Parkinson Canada Research Program
The Parkinson Canada Research Program funds research into the cure, cause, progression, improved treatment and/or understanding of Parkinson's disease, related disorders including Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), other Parkinson's conditions and the impact these diseases have on society. The following grants are offered: Pilot Project Grant, New Investigator Award, Basic Research Fellowship, Clinical Movement Disorders Fellowship, Clinical research Fellowship and Graduate Student Award. PhD, Postdoctoral Fellows
Upper $100,000 CAD for 1-2 years (varies on grants) February 3, 2020
Basic Research Fellowship
Candidates must hold a doctoral degree (MD or PhD) and may be Canadian citizens who propose to train at an Approved Institution located inside or outside of Canada, or international applicants proposing to train at an Approved Institution located in Canada. MD or PhD $40,000 - $50,000 per year (for two years) February 3, 2020
Clinical Movement Disorders Fellowship Recipient will undertake clinical training in the subspecialty of Movement Disorders and gain expertise in diagnosis and treatment of Parkinson's and may include other movement disorders. Applicants must have completed a recognized postgraduate training program in Neurology or Neurosurgery before start of program and be eligible to practice in Canada. $50,000 (one-year duration) February 3, 2020
Clinical Research Fellowship Recipient training will combine direct experience in the diagnosis and treatment of Parkinson's and in clinical research. MD $50,000 per year (for two years) February 3, 2020
Graduate Student Award At the time of application, candidates must be enrolled in a full-time graduate study program at the PhD level. Candidates may be Canadian citizens who propose to train at an Approved Institution located inside Canada or international applicants proposing to train at an Approved Institution located in Canada, who fulfill the criteria for a student visa. PhD $10,000 per year (for two years) February 3, 2020
Canadian Science Policy Fellowship
The Mitacs Canadian Science Policy Fellowship places PhD holders in government host offices for a 12-month immersion into the policy-making process. Fellows apply their academic training, critical thinking, and analytical skills to support evidence-informed decision-making that addresses policy challenges within participating federal and provincial host offices. Hosts gain valuable science-based knowledge and build the professional skills of participating fellows. Post Doctoral Fellow Upper $80,000 Lower $70,000 for 1 year February 5, 2020
Innovative Student Research Grant
The Innovative Student Research Grant, formerly called the SABA Experimental Analysis of Behavior Grant, provides funding for two students per year in psychology or behavior analysis doctoral programs and two students per year in psychology or behavior analysis master's programs that can support applied or basic research in the experimental analysis of behavior. MSc, PhD Upper $3,000 USD Lower $1,500 USD for 1 year February 12, 2020
2020-2021 Ontario Graduate Scholarship (Domestic)
The Ontario Graduate Scholarship (OGS) program encourages excellence in graduate studies at publicly-assisted universities in Ontario. Since 1975, the OGS program has been providing merit-based scholarships to Ontario's best graduate students in all disciplines of academic study. The scholarship program at U of T is jointly funded by the Province of Ontario and the University of Toronto. The Province allocates OGS awards to universities specifying the number of awards that each may offer to their students annually. Please adhere to the IMS deadline of March 1, 2020. The deadlines of SGS and other units will differ. MSc, PhD $5,000 per session for up to 2 or 3 consecutive sessions March 1, 2020
Health Careers Scholarships
Since May of 1976, the IOKDS Health Careers Scholarship Department has provided scholarships to students in health career fields. We believe that contributing to the education of compassionate health care workers assists IOKDS in "caring for all God's children through service In His Name." MSc, PhD No amount specified March 1, 2020
L'Oréal Canada/UNESCO Women in Science Research Excellence Fellowships
L'Oréal International, in partnership with several other institutions, invites applications to its Canada national fellowship. This supports ongoing research projects led by female researchers that demonstrate innovation,… more » imagination and relevance, considering scientific solutions to problems confronting humankind in the 21st century. Fellowships are annual. PhD, Post Doctoral Fellow. Applicants must be a female Canadian citizen or permanent resident Upper $20,000, lower $5,000 for 1 year March 22, 2020
J.H. Stewart Reid Memorial Fellowship Trust
The J. H. Stewart Reid Memorial Fellowship Trust was founded to honour the memory of the first Executive Secretary of the Canadian Association of University Teachers. A minimum scholarship of $5,000 is awarded annually to a student registered in a doctoral program at a Canadian university. PhD The scholarship is worth either $5,000 or 90% of the previous fiscal year's expendable income, whichever is greater, for 1 year. April 30, 2020
Graduate Scholarship Awards The Knowledge First Foundation invites applications for its graduate scholarship awards. These support students pursuing studies at the graduate level. The following awards are available: Arnold Edinborough award, Open award, Regular awards. MSc, PhD Upper $25,000, lower $10,000 May 27, 2020
CSMB Trainee Travel Awards
This bursary fund is designed to encourage student and postdoctoral fellow participation in the CSMB annual meeting, by assisting to defray the cost of attending these meetings at distant locations. MSc, PhD, Postdoctoral Fellows $100-$750 for 1 year Various
Scholarship Partners Canada Universities Canada manages government-funded international partnership programs and more than 120 scholarship programs on behalf of private sector companies. MSc and PhD Various Various
Mitacs Up to 200 senior undergraduate and graduate student, as well as postdoctoral fellows from the university can participate in research exchanges through the Globalinks Research Award pathway. Faculty at U of T and an international university from a partner country will jointly supervise research projects. PhD or Post Doctoral Fellow
$7,500 for 12-24 Weeks
3 months prior to arriving at host University
Senior Basic Science Research Fellowships The Foundation plays a leading role in the fight against diseases of the heart and circulation by supporting vital, pioneering research into their causes, prevention, diagnosis and treatment through research grants.
TalentEdge Fellowship Program (TFP) Support for Ontario PhD graduates and post-doctoral fellows to work on industry-driven R&D projects in all sectors
PhD, Post Doctoral Fellow
$35,000-$70,000 for 1 year
Continue To Explore
Homepage ›
FAQs ›
St. Michael's LI KA SHING
KNOWLEDGE INSTITUTE
St. Michael's KEENAN RESEARCH CENTRE
FOR BIOMEDICAL SCIENCE
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Toronto, ON M5B 1W8
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Contact Web Coordinator
Copyright ©2020 Research at St. Michael's Hospital. All rights reserved.


text:
var account = {};

account.settingsRelation = {
  checkboxAlwaysSign : 'alwaysSignRole',
  checkboxReportNotify : 'reportNotify'
};

account.init = function() {

  if (document.getElementById('requestConfirmationFormButton')) {
    api.convertButton('requestConfirmationFormButton',
        account.requestConfirmation);
  }

  api.convertButton('passwordFormButton', account.changePassword,
      'passwordChangeField');

  api.convertButton('deleteAccountFormButton', account.deleteAccount,
      'deleteAccountField');

  api.convertButton('saveFormButton', account.save, 'settingsField');

  api.convertButton('logoutFormButton', account.logout);

  if (document.getElementById('boardCreationDiv')) {
    api.convertButton('newBoardFormButton', account.createBoard,
        'creationField');
  }

};

account.deleteAccount = function() {

  var confirmed = document.getElementById('confirmationCheckbox').checked;

  if (!confirmed) {
    alert('You must confirm that you wish to delete your account.');
  } else {

    api.formApiRequest('deleteAccount', {
      confirmation : confirmed
    }, function requestComplete(status, data) {

      if (status === 'ok') {
        window.location = '/';
      } else {
        alert(status + ': ' + JSON.stringify(data));
      }
    });

  }

};

account.requestConfirmation = function() {

  api.formApiRequest('requestEmailConfirmation', {}, function requestComplete(
      status, data) {

    if (status === 'ok') {
      alert('Confirmation requested.');
    } else {
      alert(status + ': ' + JSON.stringify(data));
    }

  });

};

account.logout = function() {

  document.cookie = 'login=invalid+login';
  document.cookie = 'hash=invalid+hash; expires=Thu, 01 Jan 1970 00:00:00 UTC; path=/;';

  window.location.pathname = '/login.html';

};

account.changePassword = function() {

  var typedPassword = document.getElementById('fieldPassword').value;
  var typedNewPassword = document.getElementById('fieldNewPassword').value;
  var typedConfirmation = document.getElementById('fieldConfirmation').value;

  if (!typedPassword.length) {
    alert('You must provide your current password.');
  } else if (typedConfirmation !== typedNewPassword) {
    alert('Password confirmation does no match')
  } else if (!typedNewPassword.length) {
    alert('You cannot provide a blank password.');
  } else {
    api.formApiRequest('changeAccountPassword', {
      password : typedPassword,
      newPassword : typedNewPassword,
      confirmation : typedConfirmation
    }, function requestComplete(status, data) {

      if (status === 'ok') {

        alert('Password changed.');

        document.getElementById('fieldPassword').value = '';
        document.getElementById('fieldNewPassword').value = '';
        document.getElementById('fieldConfirmation').value = '';

      } else {
        alert(status + ': ' + JSON.stringify(data));
      }
    });
  }

};

account.save = function() {

  var parameters = {};

  for ( var key in account.settingsRelation) {
    parameters[account.settingsRelation[key]] = document.getElementById(key).checked;
  }

  var typedEmail = document.getElementById('emailField').value.trim();

  if (typedEmail.length > 64) {
    alert('Email too long, keep it under 64 characters');
  } else {

    parameters.email = typedEmail

    api.formApiRequest('changeAccountSettings', parameters,
        function requestComplete(status, data) {

          if (status === 'ok') {
            alert('Settings changed.');
          } else {
            alert(status + ': ' + JSON.stringify(data));
          }
        });

  }

};

account.createBoard = function() {

  var typedUri = document.getElementById('newBoardFieldUri').value.trim();
  var typedName = document.getElementById('newBoardFieldName').value.trim();
  var typedDescription = document.getElementById('newBoardFieldDescription').value
      .trim();
  var typedCaptcha = document.getElementById('fieldCaptcha').value.trim();

  if (!typedUri.length || !typedName.length) {
    alert('Uri and name are mandatory.');
  } else if (/\W/.test(typedUri)) {
    alert('Invalid uri.');
    return;
  } else if (typedCaptcha.length !== 6 && typedCaptcha.length !== 24) {
    alert('Captchas are exactly 6 (24 if no cookies) characters long.');
    return;
  } else if (/\W/.test(typedCaptcha)) {
    alert('Invalid captcha.');
    return;
  } else {
    api.formApiRequest('createBoard', {
      boardUri : typedUri,
      boardName : typedName,
      boardDescription : typedDescription,
      captcha : typedCaptcha
    }, function requestComplete(status, data) {

      if (status === 'ok') {
        window.location.pathname = '/' + typedUri + '/';
      } else {
        alert(status + ': ' + JSON.stringify(data));
      }
    });
  }

};

account.init();

redpajama_set_name: RedPajamaGithub


North East businesses would like to see the re-negotiation of Britain's relationship with the European Union, according to a North East Chamber of Commerce survey.
In the Chancellor's 2013 Budget the Government announced a commitment to make changes to the Childcare Voucher Scheme, including a pledge to provide 20% of working families' childcare costs up to £1,200 for each child.
The North East Shadow Monetary Policy Committee (MPC) was close to unanimity this week, as members voted broadly for interest rates to be held, but with some discussion over the desire for an increase.
NECC preferred supplier Chamber Utilities has helped to save an NECC member more than £50,000 over two years thanks to its expertise in the energy markets.
The region's largest business membership organisation believes councils face an avalanche of planning applications after missing the deadline to submit local plans.
For the seventh year running, the prestigious North East Accountancy Awards 2013 will be held to celebrate the very best of accounting talent in the North East.
North East dental nurses brushed up on their theory to record the best results in the country in the latest round of training exams.


Just as spring awakens the senses, so does our unique butterfly wind chime. Featuring vibrantly colored metallic butterflies and shimmering glass beads, it sways gently in the breeze to create a soothing bell chime. Let this graceful keepsake bring tranquil tones to a porch, deck or patio space.


We're a UK top 5 governance, risk and compliance software development and service provider, based in the heart of Yorkshire.
Make governance, risk and compliance power your business. Not hold you back.
Many businesses see governance, risk and compliance only as an overhead, called upon when something goes wrong. They let it become isolated from the rest of the company, creating an 'us' versus 'them' attitude. And that's confusing and frustrating for everyone.
Coaching champions: We provide the tools, training and support to engage your organisation with GRC. Throughout your journey, you'll have a team behind you who will help you measure performance, achieve your goals and demonstrate value.
Designing user-friendly systems: For Superusers, our software is powerful, advanced and configurable. For end users, the system is delightfully easy and intuitive.
Tailoring our software and services: Governance, risk and compliance is not a one-size fits all approach. Every business has different compliance and internal quality requirements.
The best results come from partnership. We become an extension of your team to solve your most important governance, risk and compliance challenges. By demonstrating our commitment to see you succeed, you will trust us to make critical business decisions.
Our 22+ years developing a powerful software solution, industry knowledge and our commitment to invest in the training and development of our talented team make you more efficient, resilient and profitable. By doing this, our customers trust us year after year.
Too many business decisions are based on inklings and ideas. Without a management system to document, communicate and manage change it's impossible to effectively govern the business, control risk and expect compliance. Our software and services provides you with a disciplined approach. This ensures your business decisions are based on evidence and giving you confidence that the systematic approach is making your business more efficient, resilient and profitable.
Qualsys was founded in 1995 by Mike Pound and Mike Bendall with a mission to transform the role of governance, risk and compliance. We are now a team of 50+ based in Sheffield, UK, delivering governance, risk and compliance solutions for some of the world's most prestigious brands.
From Melbourne to Frankfurt, Sheffield to Shanghai, our governance, risk and compliance software is used by more than 500,000 people across 120+ countries every single day.
The Qualsys team is growing fast, so we're always on the lookout for fresh talent.
If you want to empower some of the world's biggest brands and help us bring true quality to the business world, take a look at our vacancies.
Qualsys are delighted to announce that our software has been awarded the Great User Experience 2017 Award by Finances Online. Here's what the award means - and how you can read a full review of our software.
Qualsys are delighted to announce the launch of our new website and brand.
As another new year begins, the Qualsys team have reflected on the events from the past year and shared their predictions for the year ahead. We've asked members of staff from across the business to tell us what they foresee as potential GRC challenges and opportunities over the next year.
Whether it's the clocks going back next week, the drop in temperature or Bonfire Night approaching, summer is definitely long gone.
Sodexo's pharmaceutical business has grown substantially in recent years. Four years ago, there were two members of staff in the department. Now there are 63.
Mike trained as a systems analyst with the Ministry of Defence, before becoming IT procurement manager for the Employment Department. He then moved to head up the government division sales team of Apricot Computers plc (later to become ACT). Mike left to establish Qualsys with colleague Mike Bendall.
Robert has responsibility for the commercial operations of Qualsys, including sales, marketing and finance.Since joining Qualsys in September 1998 – after a 17-year, board-level career in the leisure sector – Robert has helped develop the business to its current position with a portfolio of bluechip customers, a healthy recurring income stream and a solid foundation for future growth.
Kate's all about improvement, at work and at home. After several years managing quality systems in the healthcare world, Kate brought her keen analytical mind to Qualsys, where she oversees our ISO compliance and the development cycle of our software. When she's not making Qualsys fitter, faster and stronger, she's knee-deep in Peak District mud training for her next 10k.
Michael joined Qualsys to help develop / implement a new digital strategy, engage the user community and expand our solution into new sectors and markets. As New Business & Marketing Director he is responsible for new customer success. Michael is an IRCA Internal Auditor, has an MSc Marketing Management, is a Member of Chartered Institute of Marketing (MCIM) and a Member of Institute of Enterprise and Entrepreneurs (MIOEE). In 2011, he was voted as one of the '42 under 42' by Business Insider Magazine.
Rob originally joined Qualsys on an internship as part of his degree in computer and management sciences at Sheffield Hallam University. On graduating in 2001, Rob joined Qualsys' permanent staff, immediately taking responsibility for managing the company's own IT infrastructure. Rob's aptitude for grasping new technologies and practically applying them saw rapid career progression over the following years. Rob now has direct responsibility for managing the Qualsys development effort and co-ordinating its team of developers.
Chris joined Qualsys in 2015 following a ten year career in the financial sector. Chris' wealth of experience with GRC solutions, system implementations, and project management made him a great fit for the Services Team. Chris was promoted to Services Director in 2017 and is now responsible for managing the Services Team delivery of end-to-end EQMS services. Chris has a strong ethos of PEOPLE first and this is strongly reflected in the quality and delivery of all EQMS services.In his spare time, Chris enjoys 'trying' to playing golf and spending time with his young family.
Questions? Tell us how we can help.


text:
package io.quarkus.vertx.web.mutiny;

import static io.restassured.RestAssured.when;
import static org.hamcrest.Matchers.containsString;
import static org.hamcrest.Matchers.is;
import static org.hamcrest.Matchers.not;

import java.io.IOException;

import org.junit.jupiter.api.Test;
import org.junit.jupiter.api.extension.RegisterExtension;

import io.quarkus.test.QuarkusUnitTest;
import io.quarkus.vertx.web.ReactiveRoutes;
import io.quarkus.vertx.web.Route;
import io.smallrye.mutiny.Multi;
import io.vertx.core.buffer.Buffer;
import io.vertx.ext.web.RoutingContext;

public class JsonMultiRouteWithContentTypeTest {

    @RegisterExtension
    static final QuarkusUnitTest config = new QuarkusUnitTest()
            .withApplicationRoot((jar) -> jar.addClasses(SimpleBean.class));

    @Test
    public void testMultiRoute() {
        when().get("/hello").then().statusCode(200)
                .body(is("[\"Hello world!\"]"))
                .header("content-type", "application/json");
        when().get("/hellos").then().statusCode(200)
                .body(is("[\"hello\",\"world\",\"!\"]"))
                .header("content-type", "application/json");
        when().get("/no-hello").then().statusCode(200).body(is("[]"))
                .header("content-type", "application/json");
        // status already sent, but not the end of the array
        when().get("/hello-and-fail").then().statusCode(200)
                .body(containsString("[\"Hello\""))
                .body(not(containsString("]")));

        when().get("/buffers").then().statusCode(500);

        when().get("/void").then().statusCode(200).body(is("[]"));

        when().get("/people").then().statusCode(200)
                .body("size()", is(3))
                .body("[0].name", is("superman"))
                .body("[1].name", is("batman"))
                .body("[2].name", is("spiderman"))
                .header("content-type", "application/json");

        when().get("/people-content-type").then().statusCode(200)
                .body("size()", is(3))
                .body("[0].name", is("superman"))
                .body("[1].name", is("batman"))
                .body("[2].name", is("spiderman"))
                .header("content-type", "application/json;charset=utf-8");

        when().get("/failure").then().statusCode(500).body(containsString("boom"));
        when().get("/null").then().statusCode(500).body(containsString(NullPointerException.class.getName()));
        when().get("/sync-failure").then().statusCode(500).body(containsString("boom"));

    }

    static class SimpleBean {

        @Route(path = "hello", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<String> hello() {
            return Multi.createFrom().item("Hello world!");
        }

        @Route(path = "hellos", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<String> hellos() {
            return Multi.createFrom().items("hello", "world", "!");
        }

        @Route(path = "no-hello", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<String> noHello() {
            return Multi.createFrom().empty();
        }

        @Route(path = "hello-and-fail", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<String> helloAndFail() {
            return Multi.createBy().concatenating().streams(
                    Multi.createFrom().item("Hello"),
                    Multi.createFrom().failure(new IOException("boom")));
        }

        @Route(path = "buffers", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<Buffer> buffers() {
            return Multi.createFrom()
                    .items(Buffer.buffer("Buffer"), Buffer.buffer(" Buffer"), Buffer.buffer(" Buffer."));
        }

        @Route(path = "void", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<Void> multiVoid() {
            return Multi.createFrom().range(0, 200)
                    .onItem().ignore();
        }

        @Route(path = "/people", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<Person> people() {
            return Multi.createFrom().items(
                    new Person("superman", 1),
                    new Person("batman", 2),
                    new Person("spiderman", 3));
        }

        @Route(path = "/people-content-type", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<Person> peopleWithContentType(RoutingContext context) {
            context.response().putHeader("content-type", "application/json;charset=utf-8");
            return Multi.createFrom().items(
                    new Person("superman", 1),
                    new Person("batman", 2),
                    new Person("spiderman", 3));
        }

        @Route(path = "/failure", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<Person> fail() {
            return Multi.createFrom().failure(new IOException("boom"));
        }

        @Route(path = "/sync-failure", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<Person> failSync() {
            throw new IllegalStateException("boom");
        }

        @Route(path = "/null", produces = ReactiveRoutes.APPLICATION_JSON)
        Multi<String> uniNull() {
            return null;
        }

    }

    static class Person {
        public String name;
        public int id;

        public Person(String name, int id) {
            this.name = name;
            this.id = id;
        }
    }

}


Bruker NanoSurfaces Division is the world's most trusted name in Atomic Force Microscopy, 3D Optical Microscopy, Stylus Profilometry and Tribology. Their AFM's drive the world's leading-edge research in life science, materials science, semicondoctor, electrochemistry, and many other applications. The new Dimenstion FastScan is the world's fastest and most productive AFM, offering unrivalled speed and resolution.


6 ACRES CONVENIENTLY LOCATED TO EXIT 19 OF INTERSTATE 81, HOSPITAL, AND LOWE'S WITH 5,012 SQ. FT. OFFICE BUILDING. THE BUILDING IS DIVIDED INTO TWO SECTIONS, ONE SECTIONS IS 2,765 SQ. FT. AND IS VACANT, THE OTHER SECTION IS 2,247 SQ. FT. AND IS VACANT. BOTH SECTIONS IS CONNECTED WITH A COVERED PORCH. GREAT OPPORTUNITY TO RELOCATED YOUR NEW OFFICE.


Now think of this structure as single standing structure. The laws of statics still apply – so the sum of moments and forces must all equal zero. The members with arrows (F13, F10, F11) are what stabalise the reaction and forces applied to the structure. Note that the sum of moments is taken about node 7 – as would exclude the forces of members 13 and 10 – leaving F11 to be isolated.


text:
Epipedocera zona är en skalbaggsart som beskrevs av Louis Alexandre Auguste Chevrolat 1863. Epipedocera zona ingår i släktet Epipedocera och familjen långhorningar.

Artens utbredningsområde är Nepal. Inga underarter finns listade i Catalogue of Life.

Källor

Långhorningar
zona

redpajama_set_name: RedPajamaWikipedia


text:
"Our Favorites from Venice Film Festival 2019"
The Festival del Cinema of Venice is a milestone. For the film industry for sure, because it brings together important names and artists...
Florence and the Machine in Milan, a goddess on stage
Simple concert or otherworldly experience? For anyone who was there, the presence of Florence Welch on stage was a bit like watching a...
"PornHub movie that wants to make the difference"
Well done communication is genial, innovative, intellectual. More, well done communication sneaking in our everyday life unseen, in our...
LVMH and Di Caprio for the Amazon Forest
The lung of our planet has been burning for days now and many influential people from the world of cinema, music and politics are...
"Buckle between art, fashion and jewelry - the exhibition at Palazzo Morando, Milano"
The exhibition Fibbie! Moda, Arte e Gioiello is on stage at Palazzo Morando in Milan until the 15th of September. It has been made...
Emma Watson: the violence against women
Emma Watson, at the beginning of August, helped launch a line of legal advice for people experiencing sexual harassment working in UK. In...
"Pursuit of Fashion: the greatest private collection about fashion now shown at the MET of New York"
This autumn the Metropolitan Museum of Art (Met) of New York will host "In Pursuit of Fashion: The Sandy Schreier Collection", an...
The Couture Secrets of Shape - Charles James' exhibition
The Sozzani Foundation announced the new exhibition "Charles James - The Couture Secrets of Shape", which will be open to the public...
Food. Bigger than the plate
Victoria & Albert Museum in London is hosting "FOOD: Bigger than the Plate", the new exhibition which explores how the collective choices...
All the Way Up: Bally's climb to sustainability
Bally, a Swiss brand born in 1851, has mountains in its DNA. And it is precisely on the mountains that it has returned for a mission of...
On Flower Power: the exhibition at Galleria Nazionale in Rome
Starting from July 15, the Galleria Nazionale d'Arte Moderna e Contemporanea in Rome hosts the exhibition entitled On Flower Power. The...
"The Body, the Mind, the Space": Roger Ballen's exhibition
The Sozzani Foundation, established in 2016 by Carla Sozzani and dedicated to the promotion of culture through photography, fashion, the...
Unretouched Women: exhibition at Arles – Les rencontres de la photographie
Starting from the 1st of July until the 22nd of September 2019, the photographic festival Arles- Les rencontres de la photographie in...
"Connecting Borders: Hangeul x Fashion Art". The Exhibition at Palazzo Morando
From 9th to 28th July 2019 Palazzo Morando in Milan will host "Connecting Borders: Hangeul x Fashion Art", an exhibition entirely...
BVLGARI, the story, the dream: the exhibition in Rome
From the 26th of June until the 3 rd of November 2019 the exhibition BVLGARI, the story, the dream will be open to visitors in two of...
Azzedine Alaïa's Exhibition
Paris celebrates French-Tunisian designer Azzedine and the democratization of fashion in the new exhibition "Azzedine Alaïa, Another Way...
Mani Tese: "The Fashion Experience- the truth about what you wear" in Milan
The commitment for a sustainable approach to fashion is starting to be more resonant. Indeed, an interactive exhibition has been...
Maria Grazia Chiuri receives the Légion d'honneur
A few hours after the fashion show of the Haute Couture Autumn-Winter 19/20 collection, which happened on Mon. July 1, the historic...
"The Dawn of Romanity": Fendi's Fashion Show at the Palatine Hill
Many Italian fashion houses are starting to take into consideration even more the wonders of the Eternal City, by focusing their...
Gucci will restore the Rupe Tarpea
In these last few years the Florentine Maison has demonstrated a deep interest and love for the Italian cultural heritage, which has been...

redpajama_set_name: RedPajamaCommonCrawl


The Next Generation Exchange Ltd.
The FinanceX exchange platform enables users to trade using the local currency from a range of countries. This makes trading faster and easier as users can buy/sell cryptocurrencies directly instead of a slower and more difficult method using an intermediate, such as BTC or ETH. It also means that users can trade from many different countries with no added difficulty, setting us apart from other exchanges.


Remagen's Blast and Ballistic Wall System (B2WS) is designed to resist high powered rifle fire (up to .50 cal.), extreme blast pressures, and shrapnel impacts. We can provide varying levels of protection to suit our client's unique needs. The B2WS is used in both our permanent protective structures and relocatable units such as the Entry Control Point. The modular design allows it to perform as a building component to retrofit or harden the interior or exterior of existing structures efficiently with little disruption to ongoing operations.
B2WS products offer innovative and economical solutions for anti-terrorism/force protection. Open areas inside and around buildings and structures where large numbers of people are concentrated in crowds that are walking, sitting, or standing in lines forming at ticket counters and security checkpoints have become the preferred targets for terrorists who desire to cause mass casualties and national economic disruption. Soft target protection against improvised explosives and ballistic threats is the greatest challenge facing law enforcement, anti-terrorism, and force protection professionals worldwide. The relocatable B2WS Blast and Ballistics Barrier remains stable under all anticipated terrorist initiated blast loadings, non-tornadic wind forces, and other code-required lateral loads without being attached to the floors of host buildings where they are placed. The weight of the blast barriers does not exceed 100 pounds per square foot. This allows barriers to be used on upper floors of airport terminals or other businesses.


#TBT to the Flashes of WonderCon 2017! I saw a lot of amazing Flash cosplayers last year at WonderCon! Keep an eye out for photos from this year's convention, coming up this weekend.
If the link to Instagram is working, anyway. I think the original post exceeded the limit, but I may not have configured it right.


York-Adams Area Council's principal responsibility is to provide support to its chartered organizations and their Scouting units. To learn more about any of the programs shown below, click on any of the program logos shown below.
Tiger Cubs - is for first grade boys.
Tiger Cubs have been members of Cub Scout packs for years, but the Tiger Cub program has had a whole new look since 2001, while keeping its most important elements. A new advancement plan has been added to create additional challenges and excitement for first-grade boys.
Cub Scouts - is for boys in the second through fifth grades.
In 1930, the Boy Scouts of America launched a home- and neighborhood-centered program for boys 9 to 11 years of age. A key element of the program is an emphasis on caring, nurturing relationships between boys and their parents, adult leaders, and friends.
Boy Scouts - is for boys who have graduated the fifth grade or age 11 through 17.
Boy Scouting is available to boys who have earned the Arrow of Light Award or have completed the fifth grade, or who are 11 through 17 years old, and subscribe to the Scout Oath and Law.
Varsity Scouting - is a program for young men who are at least 14 years of age but not yet 18.
Venturing - is for young men and women ages 14-20.


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Codale Plays Role in Construction of All-Electric Community
Customer • USA 08.01.2020
Codale Electric has contributed to the construction of Soleil Lofts, an all-electric community, the first of its kind in the USA.
Salt Lake City, Utah (January 6, 2020) – Codale Electric, a Sonepar company, has partnered with Sonnen, Auric Electric and Wasatch Group on the construction of Soleil Lofts, an all-electric community outside of Salt Lake City, Utah.
Construction on Soleil Lofts began in Spring 2019 with a scheduled completion date of November 2020. The all-electric community is the first of its kind in the US and consists of 5.2 megawatts of solar power and 12.6 megawatts of energy storage. Soleil Lofts aims to drastically reduce the carbon footprint of its community with its overall clean air solution. Codale provided solar racking, PV, general electrical materials, inverters and batteries to help complete the project.
"This community is the first of its kind in the US and is constructed to respond to the needs of the grid and not the other way around, as has been the traditional relationship between solar energy and the utility," said Jess Green, Renewable Energy Branch Manager for Codale. "This is the way of the future and we're excited to be a part of it."
Media Contact: Amanda Bush
amanda.bush@sonepar-us.com
About Codale
Codale Electric Supply, a Sonepar company, was founded in 1975 by Dale P. Holt. From our humble beginnings with only five employees, we have grown into one of the most innovative and fastest-growing electrical supply distributors in the nation. We are headquartered in Salt Lake City, Utah and serve a variety of markets from our thirteen branch locations throughout Utah, Nevada and Wyoming. Our vision is to become the best electric supply distributor with the best service through our commitment to excellence. For more information, visit codale.com.
About Sonepar USA
Sonepar USA is an independent, family-owned company with global market leadership in the B-to-B distribution of electrical, industrial and safety products, services and solutions. We are a proud member of the Sonepar Group, the world's largest privately-held electrical distributor. Sonepar entered the US in 1998 and has continued to grow due to strategic acquisitions and organic growth. Today, Sonepar USA is represented by 14 locally-managed operating companies with over 700 locations nationwide. For more information, visit soneparusa.com.


This is the full and detailed view of the Detective Book Club compilation which contains Skinwalkers by Tony Hillerman, along with novels by Gladys Mitchell and William L. DeAndrea.
It is a hardcover volume with no dust cover. The front and back copies are identical and display the titles and authors of the included novels, along with black and white thumbnails of the novel covers, with yellow highlights. Each novel's information is printed in a white section seeming to represent a folded paper band. The cover background is made up of thin diagonal lines in black and gray.
The same lined background appears on the spine, where the titles and author names are again printed in white rectangles. The Detective Book Club logo appears at the bottom of the spine.


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Leading and Border Casting Machines
The Elrod
The Monotype Material Maker
Letterpress printing requires more than type—word spacing, line spacing (leading), rule, fancy borders, and ornaments all contribute to the legibility and beauty of the final printed piece. Word spacing (and ornaments) are most commonly cast with a sorts caster such as a Thompson, or Monotype Type and Rule Caster. While there were attachments that could convert some type casting machines to strip casters, for large volume users the better solution was dedicated strip casting machines.
The Elrod was perfected by Benjamin Elrod in 1917. The machine is an extrusion-type device with type metal entering the mould on one side and then cooling, solidifying and being pulled from the mould on the other. The original machine only made 6 point leading. In 1920 sales and manufacture of the Elrod were transferred to the Ludlow Typograph Company, who continued to make improvements, finally developing moulds that could cast a variety of line spacing material up to 36 point, as well as type high rule. Unlike all the rest of the type casting machines discussed, the Elrod has no matrix, and is thus limited in its output to leading or continuous line material such as rule.
Ludlow Typograph Company
The Monotype Material Maker was brought to market in 1923. It is a free standing machine that incorporates optional equipment that was designed for the Monotype Composition Caster. Unlike the Elrod, the Material Maker operates on the principle of welding or fusing together cast sections of strip material. Once a cast is completed, the section of strip material is pushed partially out of the mould, leaving an end in the mould to fuse to the next cast. Because the Material Maker has a matrix that is lifted after each cast, it is capable of casting decorative border material, as well as rule and leading. It also incorporated an automated cutting mechanism that allowed the operator to set up the machine to automatically cut material of a predetermined length. While less common, the Material Maker was a far more versatile machine than the Elrod.
Lanston Monotype Company
Huss, Richard E., The Development of Printers' Mechanical Typesetting Methods 1822-1925. Charlottesville: The University Press of Virginia, 1973.
Ludlow Typograph Company, Ludlow, for Proven methods of typesetting. Chicago: Ludlow Typograph Company, ND.
Jeff Shay, Section editor
Thompson Type Caster
Type Founding


The Otago Museum is leading the way in widely adopting Radio Frequency Identification (RFID) tagging, a system that will eventually see every collection item tracked within Vernon Collection. The RFID process involves attaching a RFID tag (which contains a microchip with a unique ID encoded to its memory and a small antenna) to a collection item which can then be detected as the item travels past readers, or with a mobile device.
Integration with Google Earth and Google Maps!
From version 5.0.6, Vernon place data can be exported so that it can be shown in Google Earth. Place data in this context are address fields for people and organisations, geographic Latitude/Longitude fields, or fields controlled by the Place authority file. You can see these plotted on a map with associated text data from Vernon CMS.
Vernon Systems develops innovative software for cultural organisations to manage and share their collections. We've been dedicated to the cultural sector since 1985.


Good eats: Mayor DeBlasio holds up a cannoli at the town hall event in Coney Island.
Politics: Health care circus comes to Bay Ridge on Tuesday!
The mayor got an earful from Coney Island residents demanding a local ferry stop and more affordable housing at a town hall on Aug. 24.
Coney Islanders hit the mayor hard on issues such as the lack of housing and local jobs, and inadequate schools and transportation. Many of the complaints boiled down to feeling that the neighborhood has been left behind by the city — economically, culturally, and educationally — according to one attendee.
Daniel Ioannou, who runs the group Coney Islanders 4 Ferry, pressed the mayor on whether he would commission a new feasibility study to determine how best to extend the city's ferry service to Coney Island, which Ioannou argued would improve local transportation and access to jobs and education. He said he was disappointed with the mayor's lack of a plan of action when he said that the city will assess the ferry's first year of service next summer before extending any routes.
"If ridership levels are strong, we will then start a formal assessment in [late] 2018 of additional routes," DeBlasio said.
Ioannou said his simple request should not require so much time.
Ioannou said he created an online petition last month to bring the ferry service to Coney Island, and that it has already received nearly 1,600 signatures. He argues that the neighborhood needs the service due to its booming population.
"The biggest reason why we need a ferry in Coney Island is because our population is going to double in the next five years," Ioannou said, citing the surge in residential development.
Another questioner complained that the boom in residential development wasn't creating as much affordable housing as expected, and asked the mayor about increasing transparency in the housing sector, which she said is hobbled by developers who do not put aside enough units for the neighborhood's low-income residents.
"I mentioned that the housing situation in Coney Island is disgraceful, because of the homeless and the unaffordability of housing with these new developments coming out," said Victoria Lynch, a Coney Island resident.
Lynch said she wasn't satisfied with the mayor's response, because he simply referenced Housing Connect, a city service that facilitates applications for public housing, which she frequently hears her neighbors complain about. She said she wished he had spoken more directly about increasing accountability with developers.
Another resident complained to the mayor that he did not effectively manage Build it Back, a city-run post-Hurricane Sandy program meant to repair homes that were destroyed or damaged in Sandy. But the mayor responded by defending the work the program did for other New Yorkers and directed the question to the director of the program, which aggravated the questioner.
"I didn't think he was going to give me an answer tonight, but he didn't take accountability," said Annette Fisher, a Coney Island resident who said she received $21,000 from the program after losing $50,000 to her storm-damaged three-story home. "I didn't like this answer at all," she said.
The mayor kicked off the town hall with a list of promises meant to address several of the neighborhood's long-standing concerns.
DeBlasio promised to add 900 more school seats in the district, and said he had directed the Landmarks Preservation Commission to give the area's iconic Boardwalk landmark status. Hizzoner also pledged to allocate $2 billion to resiliency measures in Coney Island and the surrounding area, which was devastated by Hurricane Sandy five years ago.
"I don't want a Sandy to ever hurt this community again," DeBlasio said.
He called Coney Island and its people "tough and resilient," and said he sees the neighborhood as more than just a tourist destination.
"I honor the part of Coney Island that's the everyday people who are so strong and resilient," he said.
He also pointed out that students in Coney Island have a higher high school graduation rate than the city overall, and the number of children in Treyger's district enrolled in the city's pre-Kindergarten program tripled over the past four years.
But it was the mayor's characterization of the city's strong economy as a "five borough economy" that drew strong pushback from locals, who complained that the lack of local jobs and affordable housing was holding them and their neighborhood back.
Lynch said she did not regret coming to the event because she came to learn more about her neighbors' concerns, as well as the mayor's plans to tackle them, not only to sound off herself.


The Neostar Health® heated massage mat is a great alternative if you love having a massage but can't afford regular trips to a professional masseur. It allows you to sit or lie down and relax after a busy day and enjoy an all-over massage, and can then be folded up and stored away.
Not just a vibrating mat like others on the market, our Best Buy has 10 powerful massage motors that apply 5 different massage styles to your neck, back, lumbar region and thighs. You can choose tapping, pulsating, rolling, kneading or auto mode, and even add soothing heat for deeper pain relief or relaxation.
The simple remote control allows you to choose 3 different power levels for each zone from your neck and back down to your thighs. Unlike other mats it has a removable washable cover with pillow insert, and can be powered from the mains. NB: if you have a pacemaker, please consult your doctor before use.


Monday's ad is for is by Ballantine Ale, from 1953. Most of this month I've been posting Brewer's Gold ads from the 1950s, but I've shared all of the ones I could find, so for the remainder of the month there will be random Ballantine ads. In this ad, part of a small series, the focus is on "Tables," specifically tables from three specific places where you can find Ballantine Ale on the menu, in Houston, Texas, Boca Raton, Florida and Hollywood, California.


As an ardent cancer researcher, Dr. Smita Asthana has a vision to create wider awareness on cancer and its prevention, and aims to work on translational research to benefit the general public through the implementation of evidence-based research. "I have been associated with the National Institute of Cancer Prevention and Research (NICPR) and Institute of Cytology and Preventive Oncology (ICPO) since November 2004 and have progressed over a period of time from being a staff scientist to the current role of a senior scientist," says Dr. Asthana, who is presently with NICPR's Biostatistics and Epidemiology division.
"I have been working in various positions that deal with the design, execution, and evaluation of medical projects. Recently, we have concluded two major cervical cancer screening projects and conducted a screening of 10,000 women in rural areas," she tells AMOR. One project, funded by the Indian Council of Medical Research, was carried out 100 km west of New Delhi in the rural town of Dadri "as part of an operational research to see the implementation of VIA (visual inspection with acetic acid) and VILI (visual inspection with Lugol's iodine) screenings with the help of existing healthcare infrastructure," she explains.
As a leading researcher in cervical cancer screening, she completed an Indo-US collaborative project on the clinical performance of a human papillomavirus (HPV) test, used as a strategy for screening cervical cancer in rural communities, with funding from the Bill and Melinda Gates Foundation via the international non-profit global health organization PATH. "The primary objective of the project was to observe the performance of careHPV, a new diagnostic kit, in a rural setup," she says.
CareHPV is a highly sensitive DNA test, which detects 14 different types of the human papillomavirus that cause cervical cancer, providing results more rapidly than other DNA tests and is designed especially for use in clinics that lack reliable clean water or electricity. It is an incredibly cost-effective option for low-resource countries seeking to develop national cervical cancer screening and treatment programs according to PATH.
"Both projects were completed successfully and brought out research conclusions in the form of national and international publications," Dr. Asthana says. In addition to the projects, she had also developed health education materials to create cervical cancer awareness among the women of rural Indian community, while providing training to auxiliary nurses and midwives for cervical cancer screening.
Dr. Asthana graduated with a degree in Bachelor of Medicine and Bachelor of Surgery from King George Medical College (KGMC), Lucknow, Uttar Pradesh, India, before pursuing her Doctor of Medicine (MD) in Community Medicine from Ganesh Shankar Vidyarthi Memorial (GSVM) Medical College, Kanpur, India. Throughout her career, she has published over 40 articles in national and international journals. As a result of her hard work and dedication toward the medical field, she has been awarded first prizes for oral presentation in international conferences such as Indian Cancer Congress (ICC 2014) and Asia Oceania Research Organisation on Genital Infections and Neoplasia (AOGIN 2012).
She is an active member of various scientific associations and societies such as the Indian Association for Cancer Research (IACR), Indian Society for Medical Statistics (ISMS), Indian Association of Preventive and Social Medicine (IAPSM), and International Epidemiological Association (IEA). In her effort to provide impactful messages via research publications, she is currently working on remodeling the cancer registry data, which includes a diversified field for incidence of childhood cancer, breast and cervical cancer, trends of major cancer, cancer burden in Northeast of India, among other things.
According to Dr. Asthana, her vision is the utilization of voluminous cancer registry data to produce comprehensive reports in the form of research communication to give a clearer picture of different cancer burden in various Indian registries. "I have also proposed a project for establishing cancer registry at NICPR, which was approved by the Indian Council of Medical Research (ICMR) in principle, but we are currently still waiting for funding," says the medical scientist.
Focusing on the area of cancer epidemiology and research methodology, Dr. Asthana has faced many challenges commonly encountered by any researcher with a vision to improve medical research. "Gradually, with time and experience, I have overcome these limitations and I now conduct research methodology workshops to help clinicians have a better orientation toward research," she says. Dr. Asthana is the coordinator of research methodology workshops, which is a series of training courses that started in 2007. Training courses/workshops are being conducted on a regular basis — two to three times a year at ICPO — and on an invitation basis, she has held workshops at other institutions such as her previous visit to Universiti Teknologi PETRONAS in Malaysia to train 30 PhD students.
"The main aim or idea is to educate scientists/researchers and medical faculties about the basics of research methodology, which consist of descriptive statistics, statistical analysis, and clinical trial sampling, as well as research protocol development and scientific reporting/writing," she elaborates. "The curriculum was formed and executed in such a way that new scientists gain an overall knowledge on how a research project should be planned, executed, and the results communicated," she adds. The courses, according to her, are targeted for medical faculty members, medical post-graduate students, undergraduate students, and PhD students with a basic science background from various medical institutions.
When asked for her opinion about the future of cancer research, Dr. Asthana believes that targeted therapy is the future of cancer therapy, as it kills only cancer cells and not normal cells, which leads to lesser side effects. "However, the major concern is the cost of it," she says, "and it doesn't appear to be affordable in the near future." Hence, "developing countries like India should focus on the prevention of cancer through the modification of risk factors and adopting healthy lifestyles," she concludes.


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Kódži Mijata (* 15. leden 1923) je bývalý japonský fotbalista.

Klubová kariéra
Hrával za Tanabe Pharmaceuticals.

Reprezentační kariéra
Kódži Mijata odehrál za japonský národní tým v letech 1951–1954 celkem 6 reprezentačních utkání.

Statistiky

Externí odkazy
 National Football Teams
 Japan National Football Team Database

Narození v roce 1923
Žijící lidé
Japonští fotbalisté
Muži
Narození 15. ledna


You are here: Home / Community / DIY / Student Life / What Time is it? Summertime! We're on Staycation!
What Time is it? Summertime! We're on Staycation!
An increasingly popular and fun vacation is the stay-at-home-vacation or the "staycation." Staycation is a fancy term for spending your time off at home. As college students, we work all summer to save for the upcoming school year; however, we need a break, and we definitely like to have fun. Below are ten things to do over the summer that are cheap or free!
Get the bike out. There are thousands of miles of dedicated bike trails. Go for a ride.
Go shopping. Make a trip to your local mall. Window shop or splurge on yourself, and plan a wardrobe for the upcoming year.
Take a nap. Hey, vacations are to escape from daily life and to relax. Catch up on sleep in that hammock.
Take a hike. Walking is the best exercise. Find some kind of park or scenic area and plan a hike. You can even nap in the hammock there, too!
Read a book. You don't have to be sitting in a faraway place to settle in with a good summer read.
Host barbecue. Have the extended family over or host a block party. Ask everyone to bring something and share.
Go Paddle-boarding or Canoeing. If there is a river, lake, or ocean nearby, chances are pretty good there is also a paddle-board or canoe rental facility nearby as well. Both are a fun way to enjoy the water and to test your skills.
Tackle a family project. Have you been wanting to redecorate your room?
Get crafty. Have you tried to make the project you pinned forever ago?
Backyard Camp-out. Sleeping under the stars is a welcomed change of scenery. Plus, no bears.


Most Perth classes are held at Building C, 10-14 Pier Street Perth. We're also happy to come to you. The venue is BYO with some flexibility on times.
Please contact us to arrange times and your chosen venue.
We are currently seeking teachers and models for our Perth events! Check out our Jobs page for more information.


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Qpzm
LocalStats
Glamorgan Vale Demographics (QLD) Local Stats
All States/Territories Victoria ACT New South Wales South Australia Queensland Northern Territory Western Australia
Glamorgan Vale (4306) is a suburb of Brisbane, Ipswich, Queensland. It is about 39 kms from QLD's capital city of Brisbane. Glamorgan Vale is in the federal electorate of Blair.
In the 2011 census the population of Glamorgan Vale was 560 and is comprised of approximately 47.3% females and 52.7% males.
The median/average age of the population of Glamorgan Vale is 46 years of age.
88.0% of people living in the suburb of Glamorgan Vale were born in Australia. The other top responses for country of birth were 2.5% England, 2.0% New Zealand, 1.6% Scotland, 1.2% Singapore.
94.8% of people living in Glamorgan Vale speak English only. The other top languages spoken are 3.8% Language spoken at home not stated, 1.4% Other.
The religious makeup of Glamorgan Vale is 25.3% Anglican, 16.2% No religion, 16.2% Catholic, 13.9% Lutheran, 10.0% Uniting Church, 7.0% Religious affiliation not stated, 3.6% Christian, nfd, 3.4% Presbyterian and Reformed, 1.1% Jehovah's Witnesses, 1.1% Other religious affiliation .
54.5% of people are married, 29.7% have never married and 7.8% are divorced and 1.9% are separated. There are 29 widowed people living in Glamorgan Vale.
57.5% of the people living in Glamorgan Vale over the age of 15 and who identify as being in the labour force are employed full time, 32.0% are working on a part time basis. Glamorgan Vale has an unemployment rate of 5.5%.
The main occupations of people living in Glamorgan Vale are 18.7% Technicians & trades workers, 14.5% Professionals, 14.5% Managers, 13.4% Labourers, 10.7% Clerical & administrative workers, 9.9% Machinery operators & drivers, 8.8% Community & personal service workers, 8.4% Sales workers, 1.1% Occupation inadequately described/ Not stated.
The main industries people from Glamorgan Vale work in are 15.3% Manufacturing, 11.5% Construction, 9.5% Education and training, 9.2% Health care and social assistance, 7.6% Retail trade, 6.9% Public administration and safety, 6.1% Other services, 5.7% Professional, scientific and technical services, 5.0% Arts and recreation services.
47.8% of homes are fully owned, and 34.5% are in the process of being purchased by home loan mortgage. 14.3% of homes are rented.
The median individual income is $465 per week and the median household income is $1057 per week.
The median rent in Glamorgan Vale is $150 per week and the median mortgage repayment is $1517 per month.
Check out FY 2013 Tax Stats for Glamorgan Vale postcode 4306
Nearby Locations Amberley, Barellan Point, Benarkin North, Blackbutt, Blackbutt North, Blackbutt South, Chuwar, Colinton, Deebing Heights, Fairney View, Fernvale, Haigslea, Harlin, Ironbark, Karalee, Karana Downs, Karrabin, Kholo, Linville, Moore, Mount Crosby, Mount Stanley, Muirlea, Peak Crossing, Pine Mountain, Purga, Ripley, South Ripley, Taromeo, Thagoona, Vernor, Walloon, Wanora, White Rock, Willowbank, Wivenhoe Pocket,
Qpzm LocalStats Queensland Suburb of the Day: Boulia 4829 -> Central -> Queensland
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#Arab Tourism Day #Bahrain Tourism and Exhibitions Authority #Capital of Arab Tourism for 2020
Following the announcement of Manama as the Capital of Arab Tourism for 2020, and in celebration of Arab Tourism Day on February 25,
which coincides with the birth of Ibn Battuta, the Bahrain Tourism and Exhibitions Authority (BTEA) organized an introductory session for the delegation of the Arab Tourism Organization (ATO) and the tour guides in the Kingdom of Bahrain.
The Chief Executive Officer (CEO) of Bahrain Tourism and Exhibitions Authority (BTEA), Mr. Nader Al Moayyed, delivered an introductory speech during the event which is being held under the theme 'Tourism and Jobs, A Better Future for All' as part of the celebrations for Arab Tourism Day, and the selection of Manama as the "Capital of Arab Tourism for 2020".
With the support received from the Government, the tourism sector in Bahrain has witnessed great development in its tourism infrastructure and an increase in the number of incoming tourists and visitors.
This comes in line with the directives of His Majesty King Hamad bin Isa Al Khalifa, King of the Kingdom of Bahrain, and the combined efforts of the government under the directives of His Royal Highness Prime Minister Prince Khalifa bin Salman Al Khalifa and His Royal Highness Prince Salman bin Hamad Al Khalifa, Crown Prince, Deputy Supreme Commander and First Deputy Premier, to aim to strengthen Bahrain's position as a leading tourism hub on a regional level.
As a result of these cumulative efforts, the number of incoming visitors has increased by 14% during the years 2015-2019 and tourism revenues increased by 37%.
Tourism is one of the industries that are heavily reliant on human talent, which provide the highest quality of services with a personal touch to achieve a competitive advantage.
This is especially evident in comparison to other industries and sectors of the economy; which is a growing indicator of the socio-economic importance the tourism industry and its impact, as well as its capacity to accommodate and develop a large number of employees. In this manner, the tourism sector continuous to contribute towards decreasing unemployment rates by creating increased job opportunities, especially for the future workforce.
According to the World Tourism Organization (WTO), one out of ten jobs in the local economy is either directly or indirectly generated by the tourism sector.
During the event, the CEO of BTEA, Mr. Nader Al Moayyed also reiterated the importance of the development of the tourism sector as one of the Kingdom's priorities in line with the Government Action Plan, as part of BTEA's strategy which seeks to implement the National Strategy for the sector, which focuses on creating additional job opportunities for the youth.
Mr. Nader Al Moayyed also added that he considered tour guides to be the country's best ambassadors given they play an integral role in creating an impactful visit with a genuine feel, while promoting the Kingdom's rich history and best attractions, which work towards continually energizing the local tourism sector.
In light of this, the BTEA continuously ensures to provide the necessary level of support to tour guides in the Kingdom, in line with the National Strategy to build capacities of tour operators in Bahrain in collaboration with WTO.
Mr. Nader Al Moayyed also expressed his honour, to participate in celebrating Arab Tourism Day in Manama, the Capital of Arab Tourism for 2020, and extended his thanks to Dr. Bandar bin Fahad Al Fuhaid, the President of ATO, in addition to the ATO delegates for attending the celebration and for their continuous support and collaboration with BTEA.
Keywords: Arab Tourism Day Bahrain Tourism and Exhibitions Authority Capital of Arab Tourism for 2020
Category Business, Events | 2020/02/29 latest update at 10:10 AM
Source : Zawya | Photocredit : Google
Manama – Bahrain's Capital City
Three expats arrested for stealing jewellery
Conrad Hotels & Resorts to open serviced...


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Federal Judge Orders Ameren To Install Air Pollution Controls At Two Power Plants
Ameren must install devices to remove harmful air pollutants at it's plants in Festus and Labadie, thanks to a ruling from a federal judge on Monday, September 30. At the Women's Voices April program, John Hickey, Chapter Director, Sierra Club Missouri cited research affirming that air pollution, primarily from coal-fired power plants, contributes to global warming and is a public health threat. Read more about the judge's ruling here.
EPA approves plan to remove nuclear waste from West Lake Landfill after years of complaints
The chosen solution will remove about 70 percent of the site's radioactivity and dispose of the waste at an out-of-state facility…The EPA will spend the next year and a half determining how to clean up the site, how to keep workers and the community safe, and exactly where the waste will go. During that time, agency officials will decide where to send 75,000 cubic yards of contamination and how exactly workers will be protected during excavation. Learn more
To learn more about Westlake Landfill, watch the HBO.com documentary, "Atomic Homefront."
Women's Voices is a supporter of the Missouri Clean Energy Coalition whose mission is to grow our clean and renewable energy economy to reduce fossil fuel pollution, address climate change and create jobs.
Clean Air Missouri is a campaign of the Missouri Clean Energy Coalition (MCEC), which is a statewide coalition of stakeholders including elected officials, faith organizations, clean energy businesses, academic institutions, and environmental organizations who care about securing Missouri's energy future, strengthening our economy and creating a healthy environment for all Missourians.
We are committed to ensuring the state develops a comprehensive, clean energy plan that will reduce carbon pollution, build a strong economy with quality jobs, create healthy air and secure an independent energy future for our state.
Member organizations and supporters include representatives from public health organizations, environmental groups, clean energy businesses, faith communities, academic institutions and elected officials.
MCEC members are organizations that designate a contact person to join the coalition's coordinating committee, which include:
Missouri Interfaith Power and Light
Earthdance Farms
Women's Voices Raised for Social Justice
Organizing for Action – Missouri
Jewish Environmental Initiative; a committee of the Jewish Community Relations Council of St. Louis
Populists in Action
350KC
Renew Missouri
Ethical Society of St. Louis
Central Reform Congregation
Missouri Coalition for the Environment
Mid-Missouri Peaceworks/Missourians for Safe Energy
Labadie Environmental Organization
Diesel Health Project
Shir Hadash Reconstructionist Community
Members of Women's Voices believe that public transportation is an issue that involves social justice, economic justice, and environmental concerns. A comprehensive, responsive and robust system of public transportation is a necessity for citizens throughout the St. Louis metropolitan area. Individuals depend on public transportation to get to jobs, medical appointments and entertainment venues. Businesses depend on public transportation to get workers to their jobs. The elderly and disabled depend on public transportation to meet many of their needs. Lack of efficient public transportation is also an environmental issue. More cars on more roads leads to greater fuel consumption and more greenhouse gas emissions, which results in additional air pollution and contributes to global warming.
On April 6, 2010, residents of St. Louis County voted to approve a ballot measure authorizing a half cent sales tax increase to provide operating funds for MetroBus, MetroLink and Call-A-Ride services. Women's Voices endorsed this measure. However, we believe that sales taxes, in general, are regressive and disproportionately affect low and moderate-income individuals. Although we endorsed the tax increase, we also called upon Metro and local, regional and state officials to investigate alternate methods of providing long-term, sustainable support for public transportation in Missouri.
Public Water Supply
In the Spring of 2013 St. Louis City officials began to explore the possibility of an agreement with Veolia Environment, a multi-national French corporation, to take over some operations of the St. Louis City Water Department. Women's Voices, along with the the Missouri Coalition for the Environment and other groups, opposed this proposal. Veolia has a dismal track record after being involved in water operations in other cities. In Oct. 2013, after facing intense opposition, Veolia took itself out of consideration for the contract. We believe that we must always be on guard against attempts to privatize a city's water supply or operations.
Renewable Energy Standards
In February 2013 Women's Voices signed a resolution in support of full implementation of Missouri's Renewable Energy Standards. In 2008, voters passed the Renewable Energy Standards Act, which required utility companies to supply two percent of energy they sell to Missouri customers from renewable energy sources starting in 2011. That percentage gradually increased to five per cent by 2014, 10 per cent by 2018 and 15 per cent by 2021.
Read the Women's Voices Position Paper on Climate Change and Environmental Hazards
Women's Voices Programs on Environment:
Environmental Racism: Alive & Well in St. Louis
"No Time to Lose: The High Cost of Ignoring Climate Change"
Read summary here
"Nuclear Waste in Our Backyard"
"The High Cost of Cheap Meat"
Read more position paper on Climate Change and Environmental Hazards


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silviacolasanti.it » No category » Insider's baseball: The finer points of the game, as examined by the Society for American Baseball Research
Download Insider's baseball: The finer points of the game, as examined by the Society for American Baseball Research fb2, epub
by L. Robert (editor) Davids
Author: L. Robert (editor) Davids
Publisher: Scribner; First Edition edition (1983)
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Insider's Baseball book. Details (if other): Cancel
Insider's Baseball book. Details (if other): Cancel. Thanks for telling us about the problem. by. L. Robert Davids (Contributor).
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Established in Cooperstown, New York, on August 10, 1971 by sportswriter Bob Davids, it is based in Phoenix, Arizona. Its membership as of June 1, 2019, is 5,367.
Examined are such topics as: "Newly Discovered RBI Records"; "Triples, the Pirates, and Forbes Field"; "Bleacher Bums of Yesteryear"; "Moses Solomon, the Rabbi of Swat"; "Unrecognized Heroes: No-Hit Umpires". Foreword by Bill James.
The administration of the site is not responsible for the content of the site. The data of catalog based on open source database.
Rubrics: Baseball United States. by Charlotte Templin. The administration of the site is not responsible for the content of the site. All rights are reserved by their owners.
On this date in 1965, Willie Mays of the San Francisco Giants became the fifth player in major-league history to hit 500 career home . 21 saat · Herkese Açık. 1 Yorum · Haberin Tam Boyutu.
On this date in 1965, Willie Mays of the San Francisco Giants became the fifth player in major-league history to hit 500 career home runs, with a fourth-inning. 3 saat · Herkese Açık. Carl Yazstremski gets his 3,000th hit today and it comes against the Red Sox rivals, the New York Yankees.
This is a treasure trove of baseball history for statistically minded baseball fans that's also packed with intriguing marginalia. This is, as the book says (page vii), "intended to fill what we in SABR feel is a void in the reference publications that fans and media depend upon.
The book is about the history of baseball and the writer of the book, David Block, brings fresh new evidence of the origins of baseball into play.
You can write about your grandfather, who played only four games in the majors, or about Mickey Mantle
Like baseball itself, SABR is having trouble gaining a foothold among the impatient 18-to-30 crowd. The aging aspect has an effect on our numbers, said Vince Gennaro, the organization's president. We've finally gotten our membership under the average age of 60 years old, which is a significant accomplishment. You can write about your grandfather, who played only four games in the majors, or about Mickey Mantle. It's up to you. No topic is too large or small for discourse at the current gathering, which has a packed agenda.
Baseball in America and America in Baseball belongs on the bookshelf of any avid student of the game and its .
Baseball in America and America in Baseball belongs on the bookshelf of any avid student of the game and its history. It also provides interesting glimpses into the sociology of sport in America. Winner of the 2007 Robert Peterson Book Award of the Negro Leagues Committee of the Society for American Baseball When to Stop the Cheering? documents the close and often conflicted relationship between the black press and black baseball beginning with the first Negro professional league of substance, the Negro National League, which started in 1920, and finishing with the dissolution of the Negro. American League in 1957.
Subtitled "The Finer Points of the Game, As Examined by the Society for American Baseball Research," this is an anthology of 50+ short articles from the Society's journal from 1971 through 1982. Examined are such topics as: "Newly Discovered RBI Records"; "Triples, the Pirates, and Forbes Field"; "Bleacher Bums of Yesteryear"; "Moses Solomon, the Rabbi of Swat"; "Unrecognized Heroes: No-Hit Umpires". Foreword by Bill James.
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New!: Article on Ex Cope India from USAF magazine "Inside The Air Force"
New!: "The Impossible is Routine for Indian soldiers on Siachen"
New!: "Tough Terrain, Tougher IAF Men"
New!: "IAF ready for winter in Siachen"
New!: Four pages on the 1999 Atlantique shoot-down have been posted, including one photofeature.


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USF strikes 2-for-1 football deal with Alabama
The Crimson Tide will come to Raymond James Stadium on Sept. 16, 2023
Alabama football coach Nick Saban runs onto the field at Raymond James Stadium before his Crimson Tide's College Football Playoff national title game against Clemson in January 2017. (MONICA HERNDON | Times)
By Joey Knight
TAMPA ― Upon his arrival at USF last August, Michael Kelly began working the phones before powering up his desktop.
As a former ACC and College Football Playoff administrator, Kelly knew the challenges involved with non-conference football scheduling, especially for schools (such as USF) on the periphery of the power conferences.
Related: Strength of schedule? That comes with a whole lot of stress
So he began reaching out to "pretty much anyone" to gauge their interest in playing football against the Bulls in the next decade.
"Sometimes people say they just don't have any room, and some people say, 'Maybe, we'll see how it comes together,'" Kelly said.
But by casting such a wide net, Kelly landed some of the biggest brands on the college landscape, including arguably the biggest.
The school announced Thursday it has agreed to a three-game series (two games in Tuscaloosa, one in Tampa) with 11-time national champ Alabama. Less than two weeks before, the Bulls announced a similar two-for-one series with Miami. A two-for-one with Florida, set up shortly before Kelly's arrival, also looms.
Suddenly, the Bulls possess arguably the most appealing ― and daunting ― non-conference schedule over the next decade of any Group of Five program in the country. Since January, USF has added 14 games against Power Five competition over the next decade
Related: So how good is USF's non-conference slate? As good as any in the country
"I've been able to spend my first nine months here really listening and trying to survey where I think we are," Kelly said. "And it became very clear to me that our players, our coaches and our fans were all very eager and interested in playing the top teams we can in the non-conference schedule.
"We're eager to play anyone, and we're appreciative of the chance to play people, and we know it makes sense on many levels."
One of those levels is financial.
Though the USF-Alabama game contract wasn't immediately available, Kelly said in the first two games of the series, the visiting team receives a standard monetary guarantee that will cover expenses.
But for Game Three ― on Sept. 12, 2026 in Tuscaloosa ― USF will receive $1 million. Similarly, USF will receive a total of $1.2 million for a pair of trips to Louisville early in the next decade.
"We think this is the right thing for us for really all aspects concerned," Kelly said.
The USF-'Bama series opens on Sept. 16, 2023 at Raymond James Stadium. The Bulls play in Tuscaloosa on Sept. 7, 2024, and return there in '26.
The '23 contest will be Alabama's first road game against a non-Power Five opponent since a '03 trip to Hawaii. That game served as a de facto bowl trip for the Crimson Tide, who were then on NCAA probation.
The Bulls previously have played 'Bama once, losing to the Crimson Tide, 40-17, in the '03 season opener in Birmingham.
"(Bulls coach) Charlie Strong has built a strong program with the Bulls, and playing this kind of competition only makes our team better," Crimson Tide coach Nick Saban said in a UA news release.
That statement also would seem to apply to USF, though its accumulation of such non-conference heavyweights has been met with mild chagrin in Orlando.
UCF athletic director Danny White recently suggested he's not crazy about two-for-one deals, suggesting the concession of two road games in exchange for one home contest wasn't befitting a team from the American Athletic Conference, which deems itself the nation's sixth "power" conference.
Related: Is UCF's Danny White right to criticize USF's Michael Kelly?
Because it tries to schedule seven home games annually, UCF typically shuns two-for-one deals. The Knights' future slates include games against Stanford, Louisville, North Carolina and Georgia Tech, but none against the Gators, FSU or Miami.
"For me, I'm truly focused on what we think is best for USF in terms of scheduling," Kelly said.
"We want to position ourselves with interesting and attractive games for our players, coaches and fans, and position ourselves as best we can for the CFP format with our non-conference scheduling.
"And again, it's also supposed to be a lot of fun. These games are kind of why we do it."
Contact Joey Knight at jknight@tampabay.com. Follow @TBTimes_Bulls.
Joey Knight
USF Reporter
UCF continues 'War on I-4' dominance of USF with 64-57 women's hoops win
4 hours ago• USF Bulls
The Knights sweep a weekend of basketball against the Bulls.
USF's Brian Gregory irate over late whistle in Bulls' loss at UCF
Yesterday• USF Bulls
The Bulls coach doesn't hold back following his team's controversial 55-54 loss in Orlando
USF men seek to snap eight-game skid vs. UCF Knights in Orlando
Jan. 17• USF Bulls
The Bulls, who appear on the cusp of a breakthrough win, haven't defeated the Knights since 2015.
Jeff Scott: Offensive line, quarterback depth are USF's immediate recruiting needs
The new coach also has a date set for the Bulls' spring intrasquad game
New USF coach Jeff Scott's message to Bulls players: 'Those that stay will be champions'
Clemson's former co-offensive coordinator holds his first full team meeting as USF coach.
USF women face must-win game tonight at Temple ... and every night henceforth
A mediocre showing in non-conference play has hindered the Bulls' NCAA Tournament hopes.
Mitch Wilcox exudes grace, not a grudge, over final USF season
The Tarpon Springs alum insists the Bulls' disastrous 4-8 season benefited him as he prepares for the NFL draft in this week's East-West Shrine Game activities.
As second signing day nears, which positions will USF target?
A look at some of the Bulls' greatest areas of need entering the recruiting cycle's final stretch.
Clemson's Dabo Swinney, LSU's Ed Orgeron lead new wave of football coaching
Jan. 13• Gators
Goodbye, task-master ways. The duo leading their teams into the CFP national title game are all about a very personal, aw-shucks, family approach.
USF's upset bid falls just short against No. 21 Memphis
Jan. 13• Sports
The Bulls squander a 14-point second-half lead in a 68-64 loss to the Tigers at Yuengling Center.


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Q: How can I get google maps location name? I am working on an application in which I need to print the location after clicking on Google Map. I have retrieve the coordinates where the user tap on the map, Now I need to retrieve the name of the country. Is there a way to do that ?

A: Please take a look at following topics:
1) Get location name from Latitude & Longitude in iOS
2) How to retrieve user's current city name?
Quite a lot of code so I don't see any sense to copy-paste the answers. Hope, this will be helpful
UPD.: Here are the links to Google API reference:
A common tutorial: Hello Map
iOS SDK docs: Google Maps SDK for iOS

redpajama_set_name: RedPajamaStackExchange


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Changes in microbiome due to antibiotic exposure may increase risk for inflammatory bowel disease
Exposure to antibiotics in mothers may increase risk for inflammatory bowel diseases in their offspring. This is the finding of a study in mice led by researchers from NYU School of Medicine and published Nov. 27 in the journal Nature Microbiology.
The study results center on the microbiome, the mix of bacterial species that live in our intestines and co-evolved with humans to play roles in digestion, metabolism, and immunity. As rates of children's exposure to antibiotic use have increased in recent decades, the incidence of autoimmune conditions like inflammatory bowel disease or IBD have increased substantially. Many studies have now linked these trends, but only a few experiments in mice have shown microbial differences to directly increase disease risk.
Past studies have also suggested that antibiotic use changes the mix of maternal microbes transferred to offspring during birth, depriving the next generation of microbiomes the "education" needed to execute normal metabolic and immune functions.
"Our results provide strong evidence that antibiotics change the baby's inherited microbial communities with long-term disease consequences, which is especially important given the widespread use of antibiotics in young women before and during pregnancy," says Martin Blaser, MD, the Muriel G. and George W. Singer Professor of Translational Medicine at NYU Langone Health, and the study's senior author.
"Our study shows that the changes made to the microbiome by antibiotic exposure can be transmitted across generations, from moms to their offspring, which is consistent with our work and that of others in humans," adds Blaser, also a professor of microbiology at NYU Langone.
In the new study, the research team inoculated pregnant mice with mouse microbiota that had been changed by exposure to antibiotics. The researchers found that the antibiotic-induced changes in microbial populations persisted in the mothers, who then passed on the differences to their offspring. The mix of antibiotic-perturbed microbes in the pups was less diverse, with changes in the numbers of key species present. There were also more fluctuations observed in bacterial species in this group than in pups that inherited the normal microbiota.
How cell-free DNA can be targeted to prevent spread of tumors
The study then compared pups born from normal mothers with those born from mothers who were engineered to lack the gene for the immune protein interleukin 10 (IL-10), a known damper on the tendency of the immune system to create too much inflammation, and used widely in IBD studies.
In the group of IL-10-deficient pups, those that inherited the antibiotic-altered microbiomes from their mothers had IBD inflammation scores 55-fold higher than the pups that inherited a normal microbial population, showing how environmental and genetic factors combine to determine each animal's risk.
All of the mothers had been inoculated with bacterial populations that had been shaped prior to their being inoculated, so that neither they nor their pups had ever been exposed to antibiotics. This confirmed that the effects of antibiotic treatment had been passed to the next generation, say the study authors.
The team then used genomic and statistical techniques to analyze the millions of pieces of bacterial DNA in the samples. Past studies had already matched key DNA sequences to known bacterial species, enabling the team to define each pup's microbiome, and to watch the effect of each. The pups'antibiotic-altered microbe mix included less of the bacterial taxa Erysipelotrichi and more of the Verrucomicrobiae, with more expression of genes that might be particularly damaging to host tissues. The pathway identified had been previously seen in both mouse and human studies, confirming the relevance of this model.
It is well known that a portion of IBD risk is inherited, but the increased risk due to particular human genes is relatively small. The current study provides evidence that it is instead changes in microbial genes that are the passed from mothers to their children which affects risk.
"The basis for inheritance of IBD might possibly be quite different from what we had been thinking for many years," said Blaser.
http://nyulangone.org/press-releases/changes-in-bacterial-mix-linked-to-antibiotics-increase-risk-for-inflammatory-bowel-disease
Posted in: Child Health News | Microbiology | Life Sciences News | Women's Health News
Tags: Antibiotic, Autoimmunity, Baby, Biotechnology, Cancer, Children, Digestion, DNA, Education, Gene, Genes, Genetic, Genomic, Immune System, Immunology, Inflammation, Inflammatory Bowel Disease, Interleukin-2, Interleukin-6, Medicine, Metabolism, Microbiology, Microbiome, Next Generation, Pathology, Pregnancy, Protein, Research, Veterinary
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With larger than expected crowds about to descend on Disney's Animal Kingdom for the opening of Pandora: The World of AVATAR, more attractions have been added to the Extra Magic Hours offerings May 27th through the 29th.
On these dates, in addition to all of Pandora, several other areas of the park will offer entertainment and experiences during the 11pm until 1am event. Added offerings will include Expedition Everest, Primeval Whirl, Triceratops Spin, Fossil Fun Games, Tree of Life Awakenings, a third showing of Rivers of Light, and the Discovery Island Carnivale. Select food and beverage locations will remain open as well.
Only Pandora – The World of AVATAR is slated to be offered during the remaining Extra Magic Hours events from May 30th through July 4th. These events are exclusive to Walt Disney World Resort guests.


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Packing For Crazy Town
Go Deep or Go Bananas
The Ides of RUH ROH
Go deep or go bananas	by Sarah l. Allen March 17, 2020 March 17, 2020
UPDATE – it's now Monday, March 16th, 8pm.
The global clampdown IS ON. And so quickly, like a 21st Century Neutron bomb: All the buildings are still standing, it's just that our lives as we knew them are at best, on life support.
Thinking of the parents with kids now underfoot as you have to put everything you love on hold, and hunker down and hang on for dear life, right when the spring energy is right here. It's a perfect storm of Danger, Stress, and Lack and, as much for me as you – I'm going to repeat the words of Dianne Connelly:
"Life is not a pathology or a parking lot, and every day is a chance to design a way of being big enough to cradle everything we have to bear and still language a world that chooses to presence joy, gratitude, love, and laughter over misery, worry, fault-finding, and complaint."
We Have a Choice in How we Speak of this
Calling Team Portal
About Packing for Crazy Town