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Daniel and Miss Elaina Play Rocketship - Daniel has come to play with Miss Elaina today! They decide to play 'outer space,' but Miss Elaina gets upset when her cardboard telescope and spaceship accidentally break. Lady Elaine helps the friends see that they can still have fun together, even without the toys - because they're friends! They use their imaginations to keep playing, which is just as much fun! Daniel Plays at the Castle - Daniel is visiting Prince Wednesday and the boys are excited to explore Prince Wednesday's rock collection. Daniel is saddened when Prince Wednesday tells him the rocks are too delicate to play with. Daniel and Prince Wednesday learn that friendship is about more than just playing with each other's toys - it's about being together!


A MAN has dragged his ex-son-in-law to the Maintenance Court for the upkeep of one minor child.
Mr Makhi Zulu on Friday demanded $150 from Eden Chuma for the maintenance of a six-year-old boy he sired with his daughter.
"I have been taking care of his child without his contribution. The mother of the child is my daughter and she has left the child in my care. The child is in school and he needs a lot of things like uniforms. I am demanding $150 per month for his upkeep," he said.
Mr Zulu said Chuma is a self employed painter. Chuma said he could not afford the amount since he is unemployed.
"I am currently unemployed. I am a self employed painter and I don't earn much. I cannot afford to pay $150 a month. I am married and I also have other children. The only amount I am able to pay is below $70," he said.
Mr Zulu revised the amount he was claiming. "Considering he is not employed, he should pay $75 plus school fees and also buy uniforms for the child," he said. Chuma agreed to Mr Zulu's claims.


Whether it's Kylie Jenner's tweet bashing the app or the new update, Snapchat's popularity is rapidly declining.
Recently after Kylie Jenner tweeted, "Sooo does anyone else not open Snapchat anymore? Or is it just me….ugh this is so sad," Snapchat's stock went down more than 8%. With 24.5 million followers on Twitter and 9 million on Snapchat, Kylie's voice is going to be heard.
According to Reuters.com, the market value adds up to a loss of $1.5 billion. Experts are not certain that Kylie's tweet is the reason Snapchat's stock has crashed, but it's definitely hard to believe it would be a coincidence considering the decline happened the day after Kylie Jenner's tweet.
The new Snapchat update may have led to Kylie's tweet and the overall decline in the app's stock. There have been complaints and petitions to Snapchat from users saying they want the old version back and hate the new one.
"I despise it, it makes me not want to use Snapchat anymore because it's hard to use," said Veronica Ortiz, freshman.
In response to the Change.org petition and user complaints, "Snapchat promises to make a few more changes to the Friends and Discover section," adds Perez. This also comes to show how people can use their voice to change something.
Snapchat seems to be dying. Will they be able to save themselves by modifying the new design of their app? Will Instagram, or another social media platform, take their place?


The thing about internet technology is that we're always playing catch-up. First, we researched and identified the best key words for our products and services as we introduced Search Engine Optimization to our websites and eventually, our social media postings. Next, we hired a web developer to add the responsive design capability to our websites, so that they would download correctly into smartphones and tablets.
It appears that for our latest update, we must ensure that we're using long-tailed key words, i.e. phrases, that will capture the voice activated searches of Siri and Alexa. Adweek reports that 67 million voice assisted devices will be in use in the U.S. before this year ends and that's your motivation to seed your online content with phrases most likely to be recognized by A.I. enabled searches.
Notice that words such as where, find, order, how, who and where are often used in voice searches and you will be wise to include those words when you update your content for voice search optimization. As well, keep in mind that voice searches are often used when the prospect is in motion and typing is inconvenient, for example, when walking or driving.
Voice search key word phrases are like a conversation and your online content should respond in kind. Your newsletters, blog posts, FAQs page, white papers, case studies and descriptions of your products and services are ideal places to embed phrases that resemble prospect questions that are likely to be asked in voice searches.
Your prospective customers do not use industry-speak buzzwords such as leverage, growth hack, synergy, visionary, or disruptive. Is it not time to purge those words anyway? Your prospects are looking for answers, so give them the answers in everyday words that everyone uses. KISS–keep it simple, stupid—as you update your content to answer basic questions, including facts such as the products your organization sells, the services provided, the address of your business if customers can be expected to come in and the opening and closing times.
Photograph: Taping Gang Busters, the "only national (radio) program that brings you authentic police case histories." The program was broadcast from January 1936 – November 1957.
The pre-purchase experience, when prospective customers browse advertisements, search company websites and scrutinize social media feeds and online reviews to obtain information about product/ service choices and prices to confirm or modify their expectations.
The purchase itself, when product or service choices are finalized, size and color are selected and payment is made. All aspects of the purchase process must be convenient and seamless.
The post-purchase experience, as needed, where typical customer service matters such as the (on-time) delivery date will take place and resolution of questions or problems must be quickly and expertly resolved.
Customers want information The pre-purchase phase continues to grow in importance. Prospective customers want to know about you and also your competitors, so that comparisons can be made and the product or service that appears to offer the best value will be purchased.
The buying process may begin with an advertisement that you placed. If your product or service piques interest, the pre-purchase phase will progress to a visit to your company website. While on the website, social media icons will be clicked and the story you tell on those platforms will be read with interest. Pre-purchase research often concludes with a visit to online reviewing sites, such as Trip Advisor and Yelp, to confirm the value of your organization, product, or service.
Customers want convenience. It is imperative that doing business with your organization will be no-stress and easy. If you don't have the best turkey sandwich in the neighborhood, you can make up for it by being very convenient for customers to buy from you, online or in person (even as they complain about your product or prices).
Master logistics. Especially if yours is an e-commerce business, your website must be fully operational as well as easy to navigate, with an intuitive flow. Last week while shopping for client holiday gifts, I found a lovely little shop that sells very nice air plants, housed in interesting containers and in the right price range. But the website was down and I didn't have time to visit the store. Sadly, I could not buy from my small business colleague. Why the owner felt it would be a good idea to re-do a website in mid-December is beyond me.
Once an order is placed, there is the (outsourced) delivery system on which you depend. Your delivery service will be compared to Amazon, so it's advisable to take every step to ensure that merchandise deliveries meet customer expectations. If items are out of stock, make sure that you are able to give a very good approximation of when the item(s) will be available. Finally, packing must be expert to eliminate the chance of damage during transport.
Technology. There's no need to splurge on every technology product that's available, but do invest in those tools that will make a noticeable difference in the ease of doing business with you, in the pre-purchase, purchase, or post-purchase phases of the buying process. Make it easy to browse, make it easy to get questions answered, make it easy to buy, make it easy to arrange and receive delivery, make it easy to resolve problems.
Timely communication. The trick is to communicate with customers only when they will perceive the contact as beneficial. Depending on your business, that could be once a month or once a quarter. Signing customers up for a monthly or quarterly newsletter is an excellent way to keep customers up-to-date about new products or discounts on your products or services. Remember to give an opt-out choice.
Information that you've included in your newsletter can be recycled through your social media platforms and website. During the December holiday season, send cards to customers, including lapsed customers with whom you've not received an order in five years.
If there's been a problem with your product or service, or if a product is out of stock, quickly contact the customer and if the problem is serious, or the customer is upset, a telephone call is recommended.
Building and sustaining a profitable business takes planning and careful execution. Providing a superior buying experience that carries through the three buying process phases will bring customers to your organization and promote referrals, which continue to be the most effective form of advertising.
OK troops, you have just a few days left to take advantage of the biggest and easiest client outreach, retention and relationship building opportunity that we'll have all year—the December holidays. No doubt you have favorite clients whom you'd like to thank as well as retain, occasional clients with whom you'd like to work more often and lapsed clients whom you'd be thrilled to welcome back and December is the time to activate this most important component of your client outreach plan. Whether you will limit your outreach to sending a card, or you'll present a well-chosen gift to special clients, you must act very soon. I recommend that you mail cards and distribute gifts no later than December 15, to promote the impression that you are always on top of things.
Congratulations to those of you who wisely placed an order in early November for a holiday card that has your business name professionally printed inside and printed on the envelope, the recipient name and address, plus your business return address. You're all set to add a brief note of thanks, stamp, seal and mail.
Those who are not quite so organized still have a handful of days to find a box or two of cards that are suitable for clients, meaning the card will contain neither an overt Christmas theme nor religious message. Good tidings that "celebrate the season" are best for business relationships.
In addition, clients with whom you have a long-term relationship, or who provide you with generous billable hours (or you'd like to increase the chance that you will soon be on the receiving end of same) consider sending a holiday gift. Your gift is a lovely gesture that demonstrates gratitude for the business you've received and the relationship that has developed. You needn't spend a lot of money. Many useful or attractive gifts can be bought for $50.00 or less.
This year, I'll give two jars of jam that are made by an acquaintance and I'll hand deliver them to a short list of clients no later than December 18, with my holiday card tucked into the gift bag. Home made chutney or artisanal honey also make excellent gifts. Fruit or other gift baskets are a perennial holiday favorite and I've seen prices range from $40.00 to $400.00, depending on contents. An appealing take on the holiday gift basket is the California Sunflower arrangement of premium dried fruits, priced at $50.00 + shipping.
If you know that a client still finds traditional pocket calendars more convenient, I recommend the pocket diary by Time Traveler USA. I've happily used the brand for several years. The calendar offers a one-month view and has space to write in appointments. There's also include a weekly view that's spread over two pages. Diaries come in several colors and are $15 each, plus $2.50 for the gift box.
Then again, you might consider buying a tech gift. Even non-techies might appreciate potentially useful gifts such as Skullcandy wireless headphones , priced at $35.00 + shipping. Finally, if you have little time and money to spend on client gifts, look at air plants that come in attractive containters (and be sure to include the care instructions). Mahoney's Garden Center has a nice selection at various prices and they'll ship.


text:
U.S. condemns Erdogan's comments on Israel, Egypt
Tuesday 20-08-2013 08:24 PM
The U.S. Department of State logo
WASHINGTON, Aug 20 (Reuters) - The United States condemned comments by Turkish Prime Minister Tayyip Erdogan accusing Israel of having a hand in the Egyptian military's overthrow of president Mohamed Mursi, a White House spokesman said on Tuesday.
"We strongly condemn the statements that were made by Prime Minister Erdogan today. Suggesting that Israel is somehow responsible for recent events in Egypt is offensive, unsubstantiated, and wrong," White House spokesman Josh Earnest told reporters in a briefing.
Earlier on Tuesday, Erdogan told provincial leaders of his AK Party: "What do they say in Egypt? Democracy is not the ballot box. What is behind it? Israel. We have in our hands documentation." (Reporting by Susan Heavey and Roberta Rampton; Editing by Sandra Maler)

redpajama_set_name: RedPajamaCommonCrawl


text:
Botox For Drooling In Parkinson's
Lewy Body Dementia Versus Parkinson's
Cognitive Impairment In Parkinson's Disease
DiseaseFeatured
Screening For Cognitive Impairment In Parkinson's Disease: Improving The Diagnostic Utility Of The Moca Through Subtest Weighting
Cognitive Impairment in Parkinson's Disease: A Webinar
Affiliations Department of Medical Psychology, Neuropsychology and Gender Studies, University Hospital Cologne, Cologne, Germany, Institute of Gerontology & Center for Neuropsychological Diagnostics and Intervention , University of Vechta, Vechta, Germany
Affiliation Department of Neurology, University Hospital Cologne, Cologne, Germany
Affiliation Department of Medical Psychology, Neuropsychology and Gender Studies, University Hospital Cologne, Cologne, Germany
Affiliation Department of Neurology, Center for Movement Disorders and Neuromodulation, University Hospital Düsseldorf, Düsseldorf, Germany
Affiliation Department of Clinical and Developmental Neuropsychology, Faculty of Behavioural and Social Sciences, University of Groningen, Groningen, Netherlands
The Era Of Digital Cognitive Testing
The development of digital cognitive testing and the evolution of self-completed computerized assessments and wearable devices to assess cognitive functioning in daily life, provides an exciting opportunity to both improve clinical management and to obtain more sensitive outcome measures for clinical trials and will likely become a standard procedure in the future, given further technological improvements and increased access to the internet and digital devices. To reach this point, psychometric requirements , documentation and technical problems, as well as their relation to traditional tests, need to be well known.
How Are Cognitive Problems Treated
Much remains to be learned about the basic biology that underlies cognitive changes in PD. Researchers work towards the development of diagnostic tests to identify people who seem to be at greatest risk for cognitive changes and to differentiate cognitive problems in people with PD from those that occur in another disorder related but different known as dementia with Lewy bodies.
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Clinical Measures Of Cognition In Pd
Determining objective changes in cognitive function frequently involves neuropsychological testing. Test selection may depend on a number of factors such as age, education, and language. Test performance can be affected by motor function as well as physiological changes of aging . Therefore, neuropsychological testing in PD should include some measures that do not rely on manual dexterity or motor speed as these can be compromised and make it difficult to separate motor symptomatology from a given cognitive ability.
Many tests of global cognition have been studied or reviewed in PD, including the Mini-Mental State Examination, Montreal Cognitive Assessment , PD-Cognitive Rating Scale, Addenbrookes Cognitive Examination, among others.,,, Many tests covering different cognitive domains also have been used in PD. The Movement Disorder Society Task Forces for PDD and PD-MCI diagnostic criteria provide recommendations for assessments of cognitive domains and neuropsychological tests., Standardized protocols and PD-specific neuropsychological batteries may provide uniformity across multiple centers and research trials.
Cognition Deficits In Parkinsons Disease: Mechanisms And Treatment
1Department of Pediatrics, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
2Department of Neurology, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
3Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei 430060, China
As we know, the etiopathogenesis of PD characterized by irreversible disease progression is quite complicated and still lack of consensus to date, especially on the cognitive deficits of PD. A growing chorus of up-and-coming scholars ascribes the pathogenesis of PD to multineuropeptide dysfunction. Put another way, it is not only the progressive deterioration of dopaminergic neurons but defects in nondopaminergic systems that can lead to classical motor and nonmotor manifestations . Robust research component demonstrates that the early reduction of dopaminergic uptake in the frontal lobes is of crucial importance to cognitive impairment existing in PD patients . Accumulating lines of evidence suggest that the cholinergic disturbance within brainstem and corticostriatal pathways may be implicated in the pathophysiology of cognition deficits in PD . In addition, recent progress in PD has revealed that several genetic biomarkers and gene polymorphism may be connected with the generation and development of PD with cognition deficits.
2. Cognition Deficits in Parkinsons Disease
2.1. PD-MCI
2.2. PDD
3. Mechanisms
3.1. Neurochemical Substrates
3.1.1. Dopamine and Its Receptors
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What Is Normal Cognitive Aging And How Does Pd Fit In
Many people attribute cognitive changes to aging, and a major concern expressed by people with PD and their care partners is whether cognitive deficits are related to aging or to PD. Cognitive changes in people with PD need to be benchmarked against normative data and age-related changes. Cognitive decline without dementia can occur in aging, perhaps because neuropathological processes such as neuronal loss, deposition of amyloid, tau, and -synuclein, and vascular changes, often found post-mortem, are common as we age. The progression of cognitive decline is a key element in attributing changes to underlying disease-related processes. In general, cognitive changes in normal aging should not interfere significantly with everyday activities that require cognitive abilities. If they do, however, this may suggest an abnormal process and signal an increased risk of developing MCI or dementia. Changes in functional abilities and everyday activities due to cognitive decline can be difficult to identify if they are mild. Distinguishing whether problems in everyday activities are due to cognitive or motor problems in PD, or a combination of both, can be challenging, and appropriate measures for determining this are needed.
Executive Dysfunction In Parkinsons
Executive functions in cognition are higher-order mental processes, including the ability to plan, organize, initiate and regulate behavior to meet goals. Executive functioning is present in activities such as multitasking, switching tasks, and solving problems. The prefrontal cortex of the brain and the dopamine system are responsible for executive function. As PD damages these areas, executive dysfunction occurs, and executive dysfunction is one of the most common cognitive impairments found in people with PD.3,4
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Atomoxetine For Cognitive Impairment In Parkinsons Disease
Objective/Rationale:Parkinsons disease causes well known motor symptoms of tremor, slowness and stiffness, but also leads to cognitive impairment. Research has shown that early loss of cells in a brain structure called the norepinephrine-locus ceruleus in PD corresponds with the development of cognitive deficits and is a novel target for PD therapeutics. Atomoxetine is a specific norepinephrine reuptake inhibitor, which increases the availability of this critical neurotransmitter at the brain level. Researchers hypothesize that treatment with ATM will improve attention, set-shifting, information processing speed and working memory in cognitively impaired people with PD.
Project Description: This is an early Phase II trial to prove the concept that ATM can improve certain aspects of cognitive function in PD. Investigators will accomplish this with a double-blind, placebo-controlled trial of ATM in 30 cognitively impaired, non-demented people with PD. They hypothesize that ATM will improve attention, set-shifting, information processing speed and working memory without compromising motor function. Thirty study subjects will be randomized to receive either ATM or placebo. A carefully designed neuropsychological test will be administered at baseline and after 10 weeks of ATM treatment.
Anticipated Outcome:The proposed work is expected to demonstrate whether ATM is worth pursuing with a larger, definitive clinical trial.
Neurochemical Deficits In Pdd
Apathy & Mild Cognitive Impairment in Parkinson's Disease
Degeneration of subcortical nuclei in PD leads to dopaminergic, cholinergic, noradrenergic, and serotoninergic deficits. Of them, cholinergic deficits due to degeneration of the nucleus basalis of Meynert have been the most involved in PDD. In early neuropathological studies, PDD patients showed more NMB cholinergic neuronal depletion when compared with AD and non-demented PD.33,34 A greater reduction of choline acetyltransferase activity in frontal and temporal cortex was found in PDD than in PD without dementia.35 Mattila et al reported reduced choline acetyltransferase activity in the hippocampus, prefrontal cortex, and temporal cortex in PD. Reduction in the frontal cortex correlated signicantly with the degree of cognitive impairment.36 Not only pathological studies but also neuroimaging studies have pointed out a role for a cholinergic deficit in cognition in PD. Both PD and PDD have cholinergic neuron decits with vesicular acetylcholine transporter and acetylcholinesterase 37,38 imaging being the decreased VAChT more important and extensive in the cerebral cortex of PDD subjects.39
There are not consistent findings supporting an association between dementia and other monoaminergic systems.
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Pd And Cognitive Impairment: Five New Things
Longitudinal studies show that the risk of dementia in PD increases with advancing age and that nearly all patients with PD develop dementia if they survive 20 years with the disease.
CSF biomarkers are beginning to define molecular signatures that may help to stratify risk of dementia in PD and track disease progression.
Genetic association studies have revealed links to other neurodegenerative diseases and implicate lysosomal dysfunction in the pathophysiology of PD dementia.
Sleep disturbance appears to exacerbate cognitive impairment in PD in particular, REM behavior disorder shares an overlapping pattern of cognitive impairment with PD and increases the risk of dementia.
Cognitive training may help improve outcomes when incorporated in a multidisciplinary therapy program.
Screening For Mild Cognitive Impairment In Parkinsons Disease: Comparison Of The Italian Versions Of Three Neuropsychological Tests
Stefano Tamburin
1Department of Neurological and Movement Sciences, University of Verona, Piazzale Scuro 10, 37134 Verona, Italy
2Department of General Psychology, University of Padova, Via Venezia 8, 35100 Padua, Italy
3Human Inspired Technologies Research Center, University of Padova, Via Venezia 8, 35100 Padua, Italy
4Neurology Unit Pederzoli Hospital, Via Monte Baldo 24, 37019 Peschiera del Garda, Italy
5Neuromotor and Cognitive Rehabilitation Research Centre, University of Verona, Piazzale Scuro 10, 37134 Verona, Italy
Cognitive impairment is frequent in Parkinsons disease , and the spectrum of cognitive dysfunction ranges from mild cognitive impairment to PD dementia . The diagnosis of PD-D may to some extent be straightforward , but recognizing MCI in PD is more difficult. Cognitive deficits may occur early in PD course, and they can be documented in up to a quarter of newly diagnosed PD patients . The biological validity of PD-MCI as a clinical entity is supported by converging morphological, functional neuroimaging, neurophysiological, genetic, and cerebrospinal fluid and histological data showing an association between a number of neuropathophysiological variables and cognitive impairment or cognitive decline in nondemented PD patients .
After screening for inclusion criteria , 43 patients were included in the study. Demographic and clinical characteristics of patients are reported in Table 1.
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Contributions From Longitudinal Cohort Studies To Understanding Clinical Heterogeneity
Most studies investigating the nature of cognitive dysfunction in PD employ prevalent cross-sectional cohorts of patients, usually screened for the presence of dementia using the Mini-Mental State Examination . Such studies are thus inherently biased in terms of patient selection, which limits their potential to investigate more severe cognitive impairment in the form of dementia.
Large cohort studies have been instrumental in efforts to systematically address this aspect of cognitive heterogeneity. Using a community-based epidemiological approach in a population of approximately 700,000 over a 25-month incidence period, the CamPaIGN study was the first to assess the incidence of PD and parkinsonism, and the extent and natural history of cognitive deficits in the ensuing patient cohort . We identified five subgroups of patients at disease presentation, who were impaired on ToL, indicating fronto-striatal deficits, visual pattern recognition memory, indicating temporal lobe dysfunction, both ToL and pattern recognition memory, as well as a cognitively preserved subgroup and a group of patients who demonstrated marked cognitive impairment and had an MMSE score < 24, indicating dementia.
Memory Difficulties In Parkinsons
The most common difficulty for people with PD is remembering information that has previously been learned. Memory has several different processes and types, and people with PD have trouble recalling information but their long-term memory function generally remains intact. Memory cues or choices can help people with PD to retrieve information from the brains long-term storage.3,4
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Practical Management Of Pd
Geriatricians are likely to be managing increasing numbers of patients with PD-MCI in the future. Most will not have immediate access to full-neuropsychological assessment in a clinic setting, and it is the authors' opinion that the MoCA is the most useful screening tool, with published screening cut-offs for both MCI and PDD , and the advantage of an administration time of just 10 min. Further investigations are generally not required, although a routine dementia screen for reversible causes is warranted. Dopamine agonists for motor control and anticholinergic drugs for non-motor symptoms should be used with caution, or not at all. An explanation to the patient and their family that the prognosis of PD-MCI is uncertain but that in some cases it may be progressive is justified if the patient wishes to know this may prompt further discussion about future advanced care planning.
Testing For Cognitive Deficits
There is no clear consensus about the best cognitive tools to use in early PD. This is likely to contribute to the heterogeneity of impairments reported in this field. Neuropsychological tests can be divided into global screening instruments, including those used across a range of disorders as well as those specific to PD, and tests which are designed to probe particular neuropsychological domains.
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Epidemiology Predictors And Outcome
Approximately 30%40% of PD patients show cognitive impairment . Prevalence of PD-MCI may be an artifact of application methods of the criteria used for diagnosis . In the article depicting PD-MCI diagnostic criteria and assessment levels , the mean prevalence of such a category was estimated at 27%. By considering cut-off scores of neurocognitive testing, Yarnall et al. reported a variable mean prevalence of PD-MCI of 65.8% , 42.5% and 22.4% below the normative values. Then, two cross-sectional studies estimated the prevalence of PD-MCI at 33% and 64%, respectively . In the Parkinsons Disease Cognitive impairment Study , including 659 non-demented PD patients, the prevalence of PD-MCI was 39.6% in the whole sample. Few longitudinal studies have assessed the incidence of PD-MCI according to the MDS Level II criteria . The most recent study by Nicoletti et al. reported an incidence rate of PD-MCI of 184.0/1000 Pyar.
Although it is difficult to compare among studies, a considerable amount of PD-MCI patients progress to PDD when they are followed from 2 to 5 years after diagnosis . Recently, conversion rates from PD-MCI to PDD have been reported by one study more precisely as from 39% to 50% at a 5-years follow-up . Moreover, findings from longitudinal studies also documented significant rates of reversion to normal cognition of PD-MCI patients ranging from 11% to 27.8% at the same follow-up period .
Genetics: Renewed Importance Of Apoe Gba Variants And Potential Role Of Lysosomal Dysfunction
Ask the MD: Cognitive Impairment and Parkinson's Disease
Given the overlap in clinical symptoms and neuropathologic features among PDD, AD, and DLB, genetic association studies represent a powerful tool to identify areas of potential divergence in molecular mechanism and to highlight shared genetic risk factors that may represent common neurodegenerative pathways. A recent multicenter study of neuropathologically confirmed DLB cases reported 3 genetic loci with significant associations with the DLB phenotype, corresponding to the genes for APOE , Syn , and SCARB2 , a lysosomal protein previously linked to PD. Another study found that the APOE4 allele associated with DLB regardless of the presence of A pathology, suggesting that APOE may have an A-independent effect on DLB and PDD pathogenesis. The importance of APOE was further underscored by the finding that the APOE4 variant was associated with poorer cognitive performance in a study of more than 1,000 patients with PD across multiple centers. Interestingly, the authors noted that the MAPT H1 haplotype, while associated with overall PD risk, did not predict cognitive performance in this dataset. Other recent studies have been mixed with respect to association of the MAPT H1 haplotype and rate of cognitive decline in PD.,
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Managing Cognitive Impairments In Parkinsons
After a thorough evaluation to rule out other causes of cognitive impairment, patients with PD may be treated with medication, occupational therapy, and/or speech therapy. The medications used to treat cognitive impairments in people with PD are based on treatments used for Alzheimers disease. Occupational therapy can help a person with PD by providing adaptive strategies for daily activities. Speech therapy can help with language functions, as well as information processing. 3,4
Attention And Frontalexecutive Functions
In the human brain, the prefrontal cortex occupies a large portion of the cortical mantle and has extensive connections to most brain regions. It is not surprising then that the prefrontal cortex regulates the flow of information that determines how an individual will behave. The prefrontal cortex allows an individual to pay attention to one event or phenomenon to the exclusion of others, as well as switch among them. It allows one to act automatically or even override automatic actions, and act in a fashion counter to biological or environmental programming. Furthermore, the prefrontal cortex facilitates reasoning. Together, these cognitive abilities are frequently grouped together as frontalexecutive functions. Damage to the prefrontal cortex can substantially disrupt everyday functioning, while leaving many cognitive functions intact, as emphasized by the wellknown case of Phineas Gage .
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Box 2 Diagnostic Procedure Movement Disorder Society Pdd Criteria8144
Level I Parkinson disease dementia
A diagnosis of Parkinson disease based on the UK Brain Bank criteria for PD
PD developed prior to the onset of dementia
Mini-Mental State Examination below 26
Cognitive deficits severe enough to impact daily living independent of motor symptoms
Impairment in more than one cognitive domain, that is, at least two of the following aspects:
Months Reversed or Seven Backward
Lexical Fluency or Clock Drawing
MMSE Pentagons
Absence of other abnormalities that obscure diagnosis
Level II Comprehensive assessment for characterizing PDD
The level II evaluation assesses four domains:
Computerized cognitive testing
Digital computerized cognitive testing, which can be carried out remotely from patients homes, has become an interesting alternative to traditional pen-and-paper testing. Benefits of computerized testing include the opportunity for frequent testing with less learning effects, which increases the sensitivity to detect decline, cost-efficiency and the availability of large normative databases. Opportunities for conducting both remote functional assessments and digital interventions on the same online platform are being studied,.


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The debate will address what lies behind the miscarriage of justice revealed in the film, covering the political and economic context in which the film takes place and the role of the media.
Producer Marty Syjuco was born in the Philippines. He moved to New York in 2000, launching a career as a documentary filmmaker in 2004. He spent the last six years collaborating with Michael Collins on the documentary Give Up Tomorrow, about the unjust case against Paco Larrañaga.
Audrey Beltran is a human rights defender from the Philippines.


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Japanese Cartoons During the Occupation
Posted by sa29torr on October 11, 2019
Earlier this month Dr. Elisheva A. Perelman, from the College of Saint Benedict and Saint John's University, graced Siena as the history department's 2019 distinguished speaker. Dr. Perelman's research focuses on gender and labor in Japan and popular culture in history. She obtained her Ph. D at the University of California, Berkeley and currently teaches history at the College of Saint Benedict and Saint John's University. Her presentation on September 20th focused on the cartoon story by Bill Hume, Babysan, which focuses on an American solider stationed in Japan during the 1950's.
Dr. Perelman's collection originally started out as a newspaper comic that Hume wrote while he was stationed in Japan to boost morale during the war. However, after returning home, the collection became such a hit that it was published as a four book collection. Dr. Perelman touched on topics such as the intersections of American and Japanese cultures and life in Japan as a GI postwar.
In Babysan, the main character, named as such, is a Japanese women who has transformed her identity to fit in with western culture in order to form relationships with the American soldiers who were stationed in Japan. She dresses like Americans and is described as "culturally flexible." The comics focus on her relationships with the American soldiers as she forms companionships with the men in exchange for payment. Although many might think of her as a prostitute, Babysan was actually very sophisticated and acted more like a replacement wife for the soldiers until they returned home.
Throughout the comic, the soldiers who interacted with Babysan were introduced to a much broader Japanese culture than those who were not. This was due to the fact that Babysan introduced them to new places and people. In these relationships, each party was able to attain more knowledge from the other as Babysan taught them the Japanese way of life while the American soldiers taught her the American way of life. Ultimately, both were able to take what they learned home with them.
The students who attended this event were able to see the comics while Dr. Perelman elaborated on why they were so important in the time. The event described the way in which American and Japanese cultures were mixed during post war time in Japan. Dr. Perelman explained to the audience that the reason is was so important was that it spread new ideas across the globe while easing the tension between the Japanese and the Americans via comic literature.
sa29torr
Student Senate Update


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Computer and data security
In this June 13, 2019, photo, Steve Marcinkus, an Investigator with the Office of the City Commissioners, demonstrates the ExpressVote XL voting machine at the Reading Terminal Market in Philadelphia. An analysis by The Associated Press has found that the vast majority of the nation's 10,000 election jurisdictions will be managing their elections on Windows 7 or an even older operating system. (AP Photo/Matt Rourke)
Old software makes new electoral systems ripe for hacking
WASHINGTON (AP) — Pennsylvania's message was clear: The state was taking a big step to keep its elections from being hacked in 2020. Last April, its top election official told counties they had to update their systems. So far, nearly 60% have taken action, with $14.15 million of mostly federal...
AP Exclusive: New election systems use vulnerable software
WASHINGTON (AP) — The vast majority of the nation's 10,000 election jurisdictions are using Windows 7 or an older operating system to create ballots, program voting machines, tally votes and report counts. That from an Associated Press analysis. That's significant because Windows 7 reaches its "end...
FILe - In this file photo dated Tuesday, Jan. 10, 2017, British Airways planes are parked at Heathrow Airport in London.  The U.K. data regulator, the Information Commissioner's Office said Monday July 8, 2019, it is fining British Airways 183 million pounds (dollars 229 million US) over a breach that compromised information on half a million customers. (AP Photo/Frank Augstein, FILE)
LONDON (AP) — British Airways is facing a 183 million-pound ($229 million) fine over a breach that compromised information on half a million customers — the biggest penalty to date under new, tougher regulations and one that is likely to be seen as a test case for companies that fail to secure big...
FILE - This Sept. 22, 2016 file photo shows the screen of an electronic voting machine during testing at the Kennesaw State University Center for Election Systems in Kennesaw, Ga. Nearly two years ago, state lawyers said they intended to subpoena the FBI for the forensic image, or exact copy, it made of a crucial server before state election officials quietly wiped it clean. Election watchdogs want to examine the data to see if there might have been tampering. A new email obtained by The Associated Press says state officials never did issue the subpoena. (AP Photo/Alex Sanz, File)
The case of whether hackers may have tampered with elections in Georgia has taken another strange turn. Nearly two years ago, state lawyers in a closely watched election integrity lawsuit told the judge they intended to subpoena the FBI for the forensic image, or digital snapshot, the agency made...
In this photo taken on Wednesday, June 12, 2019, protesters flee after police fired tear gas during a massive demonstration outside the Legislative Council in Hong Kong. Young Hong Kong residents protesting a proposed extradition law that would allow suspects to be sent to China for trial are seeking to safeguard their identities from potential retaliation by authorities employing mass data collection and sophisticated facial recognition technology. (AP Photo/Kin Cheung)
HONG KONG (AP) — Young Hong Kong residents protesting a proposed extradition law that would allow suspects to be sent to China for trial are seeking to safeguard their identities from potential retaliation by authorities employing mass data collection and sophisticated facial recognition technology...
House Intelligence Committee Chairman Adam Schiff, D-Calif., right, joined by Rep. Devin Nunes, R-Calif, left, the ranking member, opens a hearing on politically motivated fake videos and manipulated media, on Capitol Hill in Washington, Thursday, June 13, 2019. (AP Photo/J. Scott Applewhite)
Lawmakers warn doctored videos pose national security threat
WASHINGTON (AP) — Lawmakers and experts are warning that videos altered with artificial intelligence software pose a threat to national security and the 2020 U.S. election. The technology uses facial mapping and artificial intelligence to produce videos — known as "deep fakes" — that appear genuine...
FILE - In this March 29, 2019, file photo, vehicles line up to enter the U.S. from Mexico at a border crossing in El Paso, Texas. Customs and Border Protection said Monday, June 10, that photos of travelers and license plates collected at a single U.S. border point have been exposed in a malicious cyberattack in what a leading congressman called a "major privacy breach." (AP Photo/Gerald Herbert, File)
Customs says hack exposed traveler, license plate images
Customs and Border Protection said Monday that photos of travelers and license plates collected at a single U.S. border point have been exposed in a malicious cyberattack in what a leading congressman called a "major privacy breach." The federal agency did not name the subcontractor whose computer...
FILE- In this Sept. 20, 2016, file photo, Facebook CEO Mark Zuckerberg and his wife, Priscilla Chan, smile as they prepare for a speech in San Francisco. Liam Booth, the security chief of Zuckerberg and his family, has been accused of sexual misconduct and making racist and homophobic comments about members of his staff and about Zuckerberg's wife, Chan. (AP Photo/Jeff Chiu, File)
Report: Zuckerberg security chief accused of misconduct
SAN FRANCISCO (AP) — Facebook CEO Mark Zuckerberg's personal security chief faces accusations of sexual misconduct and making racist and homophobic comments, according to a report Thursday by a business news site. In a detailed article, Business Insider cited legal letters reportedly written by...
Real estate title firm's lapse exposes data in 885M files
SANTA ANA, Calif. (AP) — A respected security blog is reporting that a flaw on the website of a major real estate title company exposed the bank account numbers and other sensitive information contained in 885 million files. Krebs On Security says the data collected by First American Financial...
A woman walks past advertisement for Huawei smartphones in Beijing on Thursday, May 16, 2019. In a fateful swipe at telecommunications giant Huawei, the Trump administration issued an executive order Wednesday apparently aimed at banning its equipment from U.S. networks and said it was subjecting the Chinese company to strict export controls. (AP Photo/Ng Han Guan)
US economic sanctions on Huawei could backfire
The Trump administration's plan to restrict exports to Chinese telecommunications powerhouse Huawei for national security reasons doesn't just up the ante in the China trade war. It could also hurt U.S. suppliers and accelerate Beijing's drive toward greater technological independence. The White...


Wolverine and Jubilee: Together Again!
Have I died and gone to dorky fashion heaven?
Outing winds down November 10 and 11 in Las Vegas.
Cibo Matto also performed, while No Doubt's Gwen Stefani watched from audience.
Concert or record featuring likes of Lauryn Hill, R.E.M., Beastie Boys being considered.
West will hit festival's main stage after Common on Saturday night.


Whether you are a seasoned home owner or first time buyer needing help, homeowners insurance presents a unique challenge for most. Let's simplify some common questions that should be considered when choosing an insurance company and how to.
It starts with contacting a company and asking for a quote. Consumer Reports recommends working with an Independent Agent to compare home insurance rates from multiple companies with one call or click. Since we are an Independent Agent, we appreciate that recommendation. But.
I think it's good to check with other captive companies as well, the ones that sell only one company. That gives you the widest range of rates and for comparison from top rated homeowners insurance companies. To avoid information overload, I recommend checking with 1 Independent Agent and 2 captive quotes, which will give you a good picture of the marketplace and where you fall in pricing.
When asking for quotes, the Agent should be asking questions about coverage and helping you estimate "How much insurance is needed to rebuild your home" because most homeowners want all of their house back in a total loss, not half of it. Make sure you focus on reconstruction values, instead of market value (how much the home is worth if you sell it/buy it), they are different. You can read more about that topic in another article by clicking here.
Know that your credit is the #1 factor in determining the cost you will pay. The better your score, the better the price. Each insurance company has their own score models and this play a part in who has the cheapest home insurance for you. The other item that impacts price the most is discounts for bundling your home and auto insurance with the same company.
The non-profit Insurance Information Institute has a great article on how to lower homeowner insurance cost Click here to read.
Service is important too. When you call or click for the quotes, do they answer promptly and do they get back to you in the time frame you expect. If not, it will probably only get worse once they have your business and move on to chase a new client.
Any progressive business in today's technology world will have reviews. Read them, they will provide some insight to how they operate with their current clients.
At the end of the day, you are choosing a promise & a piece of paper. Take your time and choose the Agent, Company and coverage that fits your comfort level.
DJ Noland is a licensed insurance professional in the state of Arkansas and managing Principal of McGhee Insurance Agency.Our offices specialize in placing insurance protection for individuals and families & businesses in Arkansas and would love to visit with you on your auto insurance, home insurance, personal umbrella insurance, business insurance, boat insurance, RV insurance, life insurance or health insurance protection to help structure a plan to protect what you've worked so hard for and will work hard for in the future.


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Q: grep after find don't show file content Usually with grep -r "word" <path> you see:
<file_path>: <line_with_word>

but if you did something like:
find . -type f -name "*.py" -exec grep "word" {} \;

You can see only the content, with grep -l you can only see the file, and I want both.

A: If you're using GNU grep, the -H option will ensure that the output is prefixed with the filename in all cases:
find . -type f -name "*.py" -exec grep -H "word" {} \;

Incidentally, you could use + here instead of \; to run grep on as many files as possible at a time:
find . -type f -name "*.py" -exec grep -H "word" {} +

redpajama_set_name: RedPajamaStackExchange


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PATEK PHILIPPE JUST CREATED A ONE-OF-A-KIND TITANIUM CHRONOGRPH, AND IT'S HEADING TO AUCTION FOR CHARITY
Patek Philippe has pulled out all the horological stops for its newest charitable timepiece.
The Swiss watchmaker has created a unique take on the flagship perpetual calendar chronograph, Reference 5270, with a rare titanium case and singular green dial. The one-of-a-kind model will lead the Children Action charity auction in November.
A titanium Patek Philippe is a rarity in and of itself. The Genevan outfit seldom uses the notoriously difficult (and expensive) material save for a few one-offs, such as the titanium Patek Philippe Ref. 5033 that pulled in $1.9 million at a Christie's auction in 2020. In fact, this is the very first time a Ref. 5270 will be cased in titanium.
For this auction, the family-owned brand has embraced the green dial trend and created an original shade for the watch's face. A far cry from the olive green featured on last year's Nautilus 5711/1A or this year's Ref. 5205R, this piece sports a striking, emerald green sunburst dial with Soleil finish. The perpetual calendar displays are harmoniously arranged, with a moon phase complication at 6 o'clock. There's also a double aperture for the day and the month at 12 o'clock and an analog date at 6 o'clock.
On the flip side, the in-house split-seconds movement, Calibre CH 29-535 PS, can be clearly spotted through a transparent sapphire crystal caseback, alongside an inscription that reads "Children Action 2022." The timepiece comes with an interchangeable solid titanium caseback, if you prefer to shield the inner workings. It also features a shiny, black alligator leather strap that's fitted with a titanium fold-over clasp. Apart from that, the timeless design of Ref. 5270 remains unchanged. You can expect the signature concave bezel and two-tier lugs, along with satin-brushed and polished pushers.
The unique chronograph will be auctioned at the biannual Children Action Gala in Geneva on November 7. Proceeds will be used to help improve the lives of impoverished children around the world. Although there's currently no pre-auction estimate, the watch will likely hammer down for seven figures given the titanium case and exclusive dial. Hey, it's all in the name of charity.
© By RACHEL CORMACK / Robb Report


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DEPA discounts for consumers on a month-by-month basis
DEPA-Gazprom gas talks now focused on pricing formula
Legislative revision ends saga for sale of PPC 17% stake
ELFE judicial administration, liquidation options considered
The government is considering two insolvency procedures for debt-laden ELFE (Hellenic Fertilizers and Chemicals), one being judicial administration, the other compulsory liquidation, based on the country's bankruptcy law.
Both options were mentioned in parliament just days ago by two leading government officials, Deputy Prime Minister Yannis Dragasakis and Minister of State Alekos Flambouraris, but neither of the two offered any further details.
ELFE's debt of 120 million euros owed to gas utility DEPA is complicating the utility's privatization plan being pursued by the government and TAIPED, the privatization fund.
If a judicial administration procedure is to be pursued, then one of the troubled company's creditors will need to take legal action at a Court of First Instance in Kavala, northern Greece, where the firm is headquartered, and request that the producer be placed under judicial administration. DEPA will need to come into the picture here.
If a compulsory liquidation procedure is to be chosen, then an investor that may be interested in taking over the company will need to be found. In this case, ELFE's creditors, which besides DEPA, include banks, PPC and others, will need to agree on a debt haircut.
Meanwhile, disclosures are abounding as to how Lavrentis Lavrentiadis, a failed businessman who acquired ELFE in 2009, manipulated a variety of associated firms that emerged from 2015 – and were tolerated by the government – to run down the fertilizer and chemicals producer and render it incapable of servicing its mountain of debt.
Details of legal action taken by Alpha Bank against ELFE in 2016 for a 15.1 million-euro loan extended in 2008, with the Greek State as the guarantor, were submitted to parliament for discussion last Friday by the main opposition New Democracy party. ELFE has failed to service this loan.


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« VP Joe Biden: Honoring a Solemn Duty to Provide Access to Justice by Supporting Foreclosure Mediation
RSI Launches State-by-State Guide to Court ADR »
Keeping Our Eyes on the Prize
Jennifer Shack, November 26th, 2010
The setting of goals or benchmarks is an essential component for a quality ADR program. Without those, a program can lack clarity of purpose and have no ability to gauge its impact on those it is serving. When we set those goals, however, it is important to ensure they are the right ones. Via Genuine Evaluation come these two gems from the health field in Australia and the UK:
1. Victorian health service performance monitoring framework
This sorry saga seems to be continuing as an exemplar of goal displacement, where organizations achieve the required targets but at the cost of the real goals.
A survey of 124 emergency department doctors last month found that hospital chiefs were not allowing doctors to activate ambulance bypass procedures when emergency departments were full, because they did not want to fail to achieve a government benchmark that says hospitals should be on bypass less than 3 per cent of each year.
Seventy per cent of the doctors said this had been a problem for them and one said it had cost lives because ambulances were delivering seriously ill patients to overcrowded emergency departments that were unable to care for them. The Melbourne Age 11 Nov 2010 (click through for Tanberg's cartoon that sums up the situation eloquently)
2. UK accident and emergency waiting time targets
By contrast, the UK government has scrapped its targets for waiting times in accident and emergency departments after evidence that this was leading to worse care:
Hospital waiting time targets, including the four hour wait in accident and emergency (A&E) departments, are to be scrapped. The Health Secretary Andrew Lansley made the announcement as he told MPs that a public inquiry would be held into the scandal-hit Mid-Staffordshire NHS Trust. Lansley said the "far-reaching reforms of the NHS [would] go to the very heart of the failures at Mid Staffs", which he called "one of the darkest chapters in our national health service".
At least 400 more people died at the hospital in Mid Staffordshire between 2005 and 2008 than would otherwise have been expected. An earlier inquiry into events at Mid Staffs found that patients endured "unimaginable distress and suffering" from poor care and were left "sobbing and humiliated" at the hospital, which had become focused on targets and cost-cutting.
Lansley told the Commons that the culture led to a situation where patients "were being discharged when they should not have been, and patients were being transferred to inappropriate wards where there was no provision to look after them". He said that Robert Francis QC, who chaired the first inquiry, had been crystal clear that the obsessive chasing after targets had created a situation in which managers and frontline staff lived in fear of losing their jobs. "We will scrap such process targets and replace them with a new focus on patients' outcomes – the only outcomes that matter," he said. (Hansard, 9th June 2010: Column 333. via WebMD Health News)
We in the ADR field often tout the ability of mediation to resolve disputes quickly. And for many courts, this is the main rationale for developing mediation programs. Decreasing the time it takes for cases to reach settlement and attaining settlement through mediation are great goals that should be tracked. We can't, however, lose sight of the main objective of mediation – to provide disputants with a positive experience that leads to the right solution for them. In short, let's not focus so much on speed and settlement that we forget about the people participating in mediation.
Tags: court programs, outcomes
This entry was posted on Friday, November 26th, 2010 at 11:43 am	and is filed under Program Evaluation, Program Management. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.
2 Responses to "Keeping Our Eyes on the Prize"
All well and good … and the metrics for "positive experience.." and the "right solution for them…"?
That's a good question, one that is hard to answer thoroughly in this space. A lot of research has been done on what creates a "positive experience" for litigants. Procedural justice – the sense that the process is just or fair – is considered to be the linchpin for a positive experience. Seminal research conducted by Allen Lind and Tom Tyler found that litigants' perception of procedural justice is based upon feeling respected and heard in the process.
Whether the mediation leads to the right solution for the parties is trickier, but self-determination and coercion go to the heart of it. Nancy Welsh has done some wonderful work in this area.


From what you have mentioned with regards to the error (Microsoft SQL Server 2005 compatibility issues) it sounds like you are trying to install the Metrel PATLink Software from the CD supplied with the GammaPAT?
You should only need to install the USB to Serial Drivers provided on the CD supplied by Metrel if you want to download to SimplyPats, the Metrel PATLink software is not needed if this is the case.
Hi Karl, contacted Metrel & guess what, they said they were unable to help as I was not using Pat Link programme. When I mentioned that I only wanted the drivers to use the Gamma Pat with windows 8, they still refused to help, although the person did say that their drivers were on the Metrel web site but a code would be needed to open them......Your view would be appreciated. I wonder if anyone else has had this problem.
I've got a feeling I may have to have version 7 put on the old lap top with windows 7.
Once again thanks for your time and effort to date. Metrel could learn some lessons from you as regards exceptional customer service. It makes you wonder how companies like them survive?
I have just read your post of 1.03pm 22.01.14 concerning the USB etc foe windows 8.1. Do you think that this is the answer for my problem?
Yes the instructions outlined on the following post will solve the issue you are having with regards to installing the USB Drivers for your Metrel GammaPat on your Windows 8 PC.
I managed to replicate the issue on one of our Windows 8 (V8.1) office PCs and contacted Metrel Technical Support for assistance, Steve who took my call immediately knew what the issue was and pointed me in the right direction.
If you need any help following the instructions, please give me a call and I will take you through it over the phone.


A powerful 16-bit Clone Tool which extends the previously implemented SRD function has now been developed. Major defects and severe scratches on the image can easily be removed or corrected. Entire areas of the image can be removed, retouched and altered. SilverFast Ai Studio can now be used for complex catalog production - without the need for additional imaging programs or tools.
This tool is included in SilverFast Ai Studio, DC Pro Studio and HDR Studio.


It was confirmed in May, 27th, 2009 by the decision #336 of XXV region council session of IV convocation.
Azure; fastener for clothes or. Chief gules; paty cross argent. The shield enframed by or cartouche and crowned by or region crown.
Gules and cross argent mean an accessory of territory to historical Volyn. Azure is symbol of water spaces. Fastener for clothes is symbol of the archeological finds.
The authors are Yu.Terlets'kyi, M.Omel'chuk.


What is value investing? How looking for good companies with discounted stock prices can help you build wealth in the stock market.
Some people believe that the stock market is financial voodoo and mumbo-jumbo, where success is a combination of luck, timing, and outsmarting other people. "Why try?" they ask. "Isn't the average investor doomed to fail?"
We believe instead that you can succeed.
Value investing is a strategy of finding stocks with prices lower than the intrinsic value of the business. That's it, but that explanation packs a lot of nuance in a few words.
What does the underlying business do?
How much money can it generate over the next several years?
What competitive advantages does it have?
What's the current price of the business relative to your desired return on investment?
What's the underlying business actually worth?
How likely are you to be wrong evaluating the business?
Again, that seems like a lot of questions, but they're fundamentally answerable in a way that other investment strategies aren't. You don't have to predict what other investors are thinking in the short term, only that they'll come to realize the stock is currently underpriced for what it is.
Successful value investing must find great and successful businesses. These businesses bring joy to their customers. They make honest profits. They manage their debt. Year after year they earn solid revenues. These are businesses anyone would want to own because they produce real money for their owners, whether they sell farm equipment or publish newspapers or help people find what they're looking for on the Internet.
When you buy shares of these companies, you own a piece of their business. Some people believe in buying and selling shares because other people believe the price of the stock will change in the next hour or day or week. Value investors buy shares in businesses which have demonstrated that they can and will continue to succeed.
A good business is not enough. Any stock worth investing in must be viable for the long haul: not just the next quarter or year, but five, ten, even twenty years. Think about Coca-Cola or IBM. These businesses continually reinvent themselves to produce new products, find new markets, and dominate their industries.
Its strong presence in the insurance business (think GEICO) provides a steady stream of cash every year in the form of premiums. Though it must occasionally pay out for claims, a well-run underwriting operation manages those costs. Don't underestimate this; lots of cash coming in regularly and cash flowing out infrequently means that there's a lot of cash coming in to buy other companies.
The strong management culture of Berkshire Hathaway, focused on the numbers, allows the managers of individual businesses to do what they do best while leveraging the parent company's position in the market as a whole. Buffett can negotiate preferred stock purchases and other financial transactions because of his reputation and history, and the market will follow him.
None of the rest of us are Ben Graham, Warren Buffett, or Charlie Munger, but we can find businesses with similar strengths and wait for them to go on sale.
A stock is more than a piece of the business. It's a share of the future revenue of the business. That's why the solidity and the earnings of the business are so important. The price a value investor pays for a stock depends on the revenue the business will produce over time. It's not investor sentiment. It's not technical analysis. It's the belief that, over time, great businesses continue to be great.
Value investors don't try to time the market to find the lowest of the low points as the best time to buy. If a company is worth owning at its current price, it's worth owning. Neither do they try to time the market to find the highest of the high points as the best time to sell. If there are better stocks to own, it's worth selling.
Investing based on the value of a business takes patience. It takes time to find great deals. Bargains happen. Perhaps the company's coming out of a tough period. Perhaps the whole market is down. Perhaps no one has noticed this little-known company with huge prospects right now. Perhaps—and ideally—you know something about the company or the industry that will produce a huge opportunity in the next few years.
Research, buy, wait, and watch. The free market rewards the patient and the thoughtful. No one has a perfect record of future predictions, but with care, you don't have to be. Choose great companies. Do some research. If you're careful and plan well, three times out of five you can reap the reward of a value investing-based buy and hold philosophy.
Trendshare's stocks section provides several tools for investors, including a value investing stock screener. These tools are built around analysis of several important metrics, including free cash flow analysis, standard financial ratios, and even a margin of safety determined by market capitalization.
Our free analysis can be a starting point for your own research, to help you pick stocks, even if you're a value investing beginner. Our articles can help you learn the basics and build your confidence as you build experience and real wealth in the market.


DEEP POLITICS FORUM > Drugs > "..US admits to guarding, assisting lucrative Afghan opium trade"
View Full Version : "..US admits to guarding, assisting lucrative Afghan opium trade"
Afghanistan is, by far, the largest grower and exporter of opium in the world today, cultivating a 92 percent market share of the global opium trade. But what may shock many is the fact that the US military has been specifically tasked with guarding Afghan poppy fields, from which opium is derived, in order to protect this multibillion dollar industry that enriches Wall Street, the CIA, MI6, and various other groups that profit big time from this illicit drug trade scheme.
Prior to the tragic events of September 11, 2001, Afghanistan was hardly even a world player in growing poppy, which is used to produce both illegal heroin and pharmaceutical-grade morphine. In fact, the Taliban had been actively destroying poppy fields as part of an effort to rid the country of this harmful plant, as was reported by the Pittsburgh Post-Gazette on February 16, 2001, in a piece entitled, Nation's opium production virtually wiped out (http://news.google.com/newspapers?n…).
But after 9/11, the US military-industrial complex quickly invaded Afghanistan and began facilitating the reinstatement of the country's poppy industry. According to the United Nations Drug Control Program (UNDCP), opium cultivation increased by 657 percent in 2002 after the US military invaded the country under the direction of then-President George W. Bush (http://www.infowars.com/fox-news-ma…).
More recently, The New York Times (NYT) reported that the brother of current Afghan President Hamid Karzai had actually been on the payroll of the CIA for at least eight years prior to this information going public in 2009. Ahmed Wali Karzai was a crucial player in reinstating the country's opium drug trade, known as Golden Crescent, and the CIA had been financing the endeavor behind the scenes (http://www.infowars.com/ny-times-af…).
"The Golden Crescent drug trade, launched by the CIA in the early 1980s, continues to be protected by US intelligence, in liaison with NATO occupation forces and the British military," wrote Prof. Michel Chossudovsky in a 2007 report, before it was revealed that Ahmed Wali Karzai was on the CIA payroll. "The proceeds of this lucrative multibillion dollar contraband are deposited in Western banks. Almost the totality of revenues accrue to corporate interests and criminal syndicates outside Afghanistan" (http://www.thirdworldtraveler.com/A…).
But the mainstream media has been peddling a different story to the American public. FOX News, for instance, aired a propaganda piece back in 2010 claiming that military personnel are having to protect the Afghan poppy fields, rather than destroy them, in order to keep the locals happy and to avoid a potential "security risk" — and FOX News reporter Geraldo Rivera can be heard blatantly lying about poppy farmers being financially supported by the Taliban, rather than the CIA and other foreign interests.
So while tens of thousands of Americans continue to be harmed or killed every year by overdoses from drugs originating from this illicit opium trade, and while cultivation of innocuous crops like marijuana and hemp remains illegal in the US, the American military is actively guarding the very poppy fields in Afghanistan that fuel the global drug trade. Something is terribly wrong with this picture.
This article originally appeared at Natural News.


New members of the order Cnemidolestida (Insecta: Perlidea) from Middle Permian–Middle Triassic localities of Eurasia are described. Tillyardembia zalazna sp. nov. (Upper Permian, Vyatkian; Zalazna locality, Russia) and Udembia udmurtica gen. et sp. nov. (Middle Permian, Urzhumian; Kostovaty locality, Russia) are assigned to the family Tillyardembiidae. Micropermula ceceya sp. nov. (Upper Permian, Severodvinian; Bor Tologoi locality, Mongolia), Sibestia nana gen et sp. nov. (Middle Permian, Kazanian; Kaltan locality, Russia), Votyak pictus gen. et sp. nov. (Kostovaty locality), Vokhmia pyriformis gen. et sp. nov., V. laxa gen. et sp. nov. (Upper Permian, Vyatkian; Nedubrovo locality, Russia), and Aiban kichineis gen. et sp. nov. (Middle Triassic, Ladinian; Madygen locality, Kyrgyzstan) belong to the family Sylvabestiidae. Issatermes parvus gen. et sp. nov. (Issatermitidae fam. nov.) is described from the Upper Permian Isady locality (Severodvinian of Russia).


text:
Q: SQL Server create checksum out of multiple rows I have a table with product delivery information. I get daily files, which append to this table. But, if something goes wrong with the import,I can't simply reimport the same file, as it already might have imported some of the data and then I would have duplicates.
I am thinking about adding a checksum/hash row so I can compare the lines and omit already existing stuff.
The table looks like this (simplified):

*

*id (identity row, integer)

*ordernr (integer)

*item (varchar)

*itemcount (integer)

*deliverydate (date)

*... some more stuff

I would like to add a row 'checksum', which would be a combined hash of the rows ordernr, item, itemcount and deliverydate. As the table is fairly large (1m+ rows),I would even prefer a right(hash,8), so a varchar(8) would be enough for the checksum row.
So far I got here:
SELECT o1.rdid, HASHBYTES('md5', (
    SELECT ordernr, item, deliverydate, itemcount
    FROM shop_tt_deliveries_uk o2
    WHERE o2.rdid = o1.rdid FOR XML RAW))
FROM shop_tt_deliveries_uk o1

that generates hashes likes this:
rdid    (No column name)
98851   0xA819EEB0B7463DCB11AE8170879F867C
98852   0x73DB5FE112707BB3D9564DE063882F30
98853   0x3F81DBCED4D6B200CD605BC774FD5EB4
98854   0xF388A700995F8B589AE31CFE0AEF9568

but already adding the right() result in strange stuff (where i was expecting '879F867C' for the first line):
rdid    (No column name)
98851   ®p‡Ÿ†|
98852   ÙVMàcˆ/0
98853   Í`[Çtý^´
98854   šãþ

and updating the table does not work at all:
UPDATE shop_tt_deliveries_uk d
SET checksum = HASHBYTES('md5', (
    SELECT ordernr, item, deliverydate, itemcount
    FROM shop_tt_deliveries_uk o2
    WHERE o2.rdid = o1.rdid ))
WHERE checksum IS NULL

Any insights?

A:  declare @source varbinary(max), @id int
 declare chk cursor for SELECT o1.rdid, HASHBYTES('md5', (SELECT ordernr, item, deliverydate, itemcount FROM shop_tt_deliveries_uk o2 WHERE o2.rdid = o1.rdid FOR XML RAW)) FROM shop_tt_deliveries_uk o1
open chk
fetch next from chk into @id, @source
while (@@fetch_status = 0)
begin
  select @source = right(cast('' as xml).value('xs:hexBinary(sql:variable("@source"))', 'varchar(max)'),8)
  update shop_tt_deliveries_uk d SET checksum = @source WHERE checksum IS NULL //put your more conditions
  fetch next from chk into @id, @source
end


text:
package com.blazebit.persistence.impl.function.datetime.epochday;

/**
 * @author Moritz Becker
 * @since 1.2.0
 */
public class PostgreSQLEpochDayFunction extends EpochDayFunction {

    public PostgreSQLEpochDayFunction() {
        super("cast(extract(epoch from ?1) as int) / " + (24 * 60 * 60));
    }
}

redpajama_set_name: RedPajamaGithub


These workshops are designed around the requirements for the Boy Scouts Pottery Merit Badge.
Classes are open to anyone in the age range, but most of the spots are reserved for Scouts.
Hosted by Scenic City Clay Arts in our downtown community ceramics studio, students will receive an introduction to ceramics with hands-on learning and creating. This is an excellent indoor, winter activity to introduce cub scouts to Ceramics.
Week 1 will cover vocabulary & safety and students will make one of each: slab pot, coil pot, pinch pot, and animal or human figure.
Week 2 students will glaze and paint their pieces and receive a lesson on the kiln firing process.
COST: $50 *Please provide an email address when you register, so that we can contact you about the workshop.
Dates/Times: TBD. Check back in for the next scheduling of this workshop.
Hosted by Scenic City Clay Arts in our downtown community ceramics studio, this workshop will cover all the Scouts BSA requirements for earning the Pottery Merit Badge.
Week 2 students will use glazes and/or underglazes to decorate their five pieces and will learn about SCCA's electric kiln along with general kiln firing processes.
Workshop is led by professional potters and ceramics instructors Nicole Johnson and Loren Howard and has been approved by the Boys Scouts of America, Cherokee Area Council.
COST: $80 *Please provide an email address when you register, so that we can contact you about the workshop.
All future Boy Scouts Programs are in the process of being scheduled. Check back later for more updates on classes!


text:
Children "As Young As Four" Are Mining The Mineral Used In Our Smartphones
Tags: Human Rights, Sweatshop
by Luke Miller,
From 1998 to 2008 an estimated 5.4 million people have died due to the conflict in the country currently known as the Democratic Republic Congo. To put this into perspective it was estimated that 6 million people died, in the Holocaust. While the war and displacement have been fluctuating since this time, the country is still being plagued by violence from rebel groups who continue to operate there. The displacement of hundreds of thousands of people a year have continued to occur over the last decade. But renewed fighting and conflict from 2016 to 2017 caused the displacement of an estimated 2.2 million people, at the end of which 4.5 million people were living in a situation of displacement.
At first glance, this may not seem like a problem that the everyday westerner is contributing to, but when you dig a little deeper there is a different story to be told.
Coltan is the conflict mineral that is in nearly every cell phone, laptop, and electronic device, and the Democratic Republic of Congo (DRC) is the world's leading supplier of this mineral. DRC is very mineral rich also supplying the world with copper, diamond, tantalum, tin, and gold. In 2009 (DRC) had an estimated $24 trillion in unmined mineral deposits, which included the world's largest reserves of coltan.
Rebel wars and conflict have been a constant in DRC for the past 20 years, but in late 2000, a huge demand for coltan spiked when the PlayStation 2 caused a dramatic rise in its price. With this spike came intensified violence in Eastern Congo, as according to a U.N. report the rising price "brought in as much as $20 million a month to rebel groups". Then in the mid-2000s with the smartphone boom, demand for this mineral has progressively intensified year after year.
A 2016 Sky investigation found that mines in DRC employ children "as young as four" to work in the coltan mines, in desperately dangerous conditions. The children earn wages as low as 8p (10 cents) a day, are made to dig the mines barehanded and are often subjected to violence and intimidation.
Reports show that corporations such as Apple, Sony, and Samsung are using coltan from these mines, which have "little to no labor regulations". In 2016, Amnesty International released a report showing that many of these companies fail to do basic checks which could help prevent this child labor.
In 2017 Washington Post reported Apple would temporarily stop buying coltan which is hand mined in Congo, with a spokesperson saying "We have been working with (mining company) Huayou on a program that will verify individual artisanal mines, according to our standards," and continued "these mines will re-enter our supply chain when we are confident that the appropriate protections are in place."
With this in mind, the war continues to intensify with many leading electronic suppliers refusing to stop supporting the conflict.
I'm Luke Miller the author of this article. I like to blend psychology and spirituality to help you create more balance in your life. Grab a copy of my free 33 Page Illustrated eBook- Psychology Meets Spirituality- Secrets To A Supercharged Life You Control here!
Credits: 123Rf SkyNews
Written by: Luke Miller
I am Luke Miller a poet, writer and deep thinker! Everything I do is centred around the rebalance of the power structure to one that is harmonious, loving and benefits humanity in its entirety. We are entering a new age of love and I am here to encourage others to be a part of it! (Rev)olution R(evol)ution R(evolution) Revolut(ion) R(evolve)ut(ion) Or (Revolve)ut(ion) Read More stories by Luke Miller
? Luxembourg Will Make All Public Transport Free From Next Year 20 Year Harvard Study Reveals Orange Juice May Reduce Chances Of Memory Loss By 47% ?


text:
NewCanaanite.com (https://newcanaanite.com/did-you-hear-208-1058233)
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Saying the tenants of an East Hills Drive duplex haven't paid rent this calendar year, the homeowner on April 16 filed eviction papers in state Superior Court. The month-to-month payment of $1,750 hasn't been made by the four occupants of 9 East Hills Drive since January, according to a complaint filed by Norwalk-based attorney Abram Heisler. The complaint identifies two of the tenants by name and says the property owner doesn't know who the other two people living there are.
Zach Allen sacking some Darien quarterback. Credit: Terry Dinan
Experts say 2015 New Canaan High School graduate Zach Allen— the Rams' all-time sack leader—could be selected in the middle of the second round of the NFL draft on Friday. The defensive end is finishing his fourth year at Boston College.
The New Canaan Building Department on April 22 issued an after-the-fact building permit for a $14,000 kitchen renovation job at 19 Olmstead Court. The homeowner served as contractor for the work, the permit said, and paid the town $205 in fees.
Paul Simon has listed his New Canaan home for $13.9 million, according to Architectural Digest.
Tony's Deli earned a perfect score from the New Canaan Health Department during its April 16 re-inspection of the Pine Street eatery.
Philippe Petit walking between the twin towers of the World Trade Center on a wire. Courtesy Philippe Petit
The Glass House's annual Summer Party—to be held June 8—this year will feature a site-specific aerial walk by French high-wire artist Philippe Petit, of "Man on Wire" fame.
The Board of Selectmen voted 3-0 Tuesday to appoint Karen Ludwig Kariuki to the Tourism and Economic Development Advisory Committee, and Beth Ann Brunalli to the Inland Wetlands Commission.
The Town Council on Wednesday voted 12-0 to oppose forced regionalization of schools.
Here's some worthwhile events coming up soon, book 'em:
Annual Fishing Derby—Registration starts 8 a.m. on Saturday, April 27 at Mill Pond (derby starts 8:30 a.m.)
Collection Days for Boy Scouts Troop 70 Annual Fundraiser—9 a.m. to 3 p.m. on Saturday and Sunday, April 27-28 in the Lumberyard Lot (opposite Karl Chevrolet)
Scandals, Standardized Testing & Sports—7 to 8:30 p.m. on Tuesday, April 30 at Woodway Country Club (540 Hoyt St., Darien)
Dog Days New Canaan—free entry 12 to 4 p.m. on Saturday, May 4 at New Canaan Nature Center (44 Oenoke Ridge Road)
STAR Inc. Walk, 5k Run and Roll—9 a.m. to 1 p.m. on Sunday, May 5 at Sherwood Island State Park, Westport
New Canaan CARES 27th Annual Kitchen & Home Tour— 10 a.m. to 3 p.m. on Thursday, May 16
May Fair—5 to 10 p.m. on Friday, May 10 (Friday Night Lights) and 9 a.m. on Saturday, May 11 at St. Mark's
The selectmen on Tuesday also unanimously approved payment of legal bills that included $4,042 in the case of Grace Farms's lawsuit versus the Planning & Zoning Commission ($33,070 fiscal-year-to-date), $1,480 for a review of the school district's food service thefts ($15,770 fiscal-year-to-date) and $2,984 for a lawsuit brought against a New Canaan Country School neighbor in connection with P&Z's approval of a new athletic facility ($9,557 fiscal-year-to-date).
Local players on the Eclipse Lacrosse Club U13 National Team. Contributed
Congratulations to the Eclipse Lacrosse Club U13 National Team, which is bound for the World Series of Youth Lacrosse July 2 to 4 in Denver with a chance to play in the championship game at Denver University's Peter Barton Stadium. Head-coached by Will Koshansky, the team includes town residents Doster Crowell, Colin Finnigan, Thomas Garcia, Hayden Roeder, Jack Sconziano and Gray Tamasco.
L-R: U.S. Rep Jim Himes, Bankwell EVP & Chief of Staff Laura Waitz, Bankwell AVP & Marketing Manager Lucy French holding Zumba, Photographer Mike Bagley and Bankwell Executive assistant to the CEO, Lynne Gomez holding Bowie. Contributed
Bankwell on Thursday announced the re-launch of its Bankwell Pet Adoption Project, creating awareness about the many dogs and cats in need of homes at animal shelters throughout Fairfield and New Haven Counties. This is the third year for the program, which features photos and information about available dogs and cats on billboards, ads, social media, the bank's website, and throughout all of the bank's branches. The bank kicked off the program in the spring of 2017, and the adoption rate at local shelters spiked, with more than 85% of featured animals finding a home last year.
Finally, New Canaan Human Services is asking residents to check on older loved ones and neighbors throughout the year. New Canaan's community health nurse offers monthly wellness visits to New Canaan's disabled or senior residents that find it too difficult to leave their home, including a blood press use check, safety assessment and discussion of health concerns. Those interested in the program should contact contact Bethany Zaro, 203-594-3093 or bethany.zaro@newcanaanct.gov.
Did You Hear
Disorderly, Assault Charges for New Canaan Man, 32
Firefighters Extinguish Blaze at Old Stamford Road Home Early Saturday
One thought on "Did You Hear … ?"
Edwin Amaya on April 26, 2019 at 10:07 pm said:
Zach Allen got drafted by the Arizona Cardinals with the 65th pick. Congrats to him.


In the latest of a series of civil penalties he's received, Memphis Democrat Joe Towns was hit with a $10,000 fine by state officials for filing a campaign disclosure statement late.
The Tennessee Registry of Election Finance, an entity within the Bureau of Ethics and Campaign Finance, issued the fine against Towns on Wednesday because the longtime lawmaker did not file his first quarter campaign disclosure filing until Aug. 9 — almost four months after the report was due.
During the registry's meeting, a board member dubbed Towns a "frequent flyer" before assessing the $10,000 fine. Norma Lester, a Memphis-based board member, recused herself from voting.
The $10,000 fine is the latest penalty Towns has faced since being assessed his first fine in 1996. Since then, Towns has paid more than $65,000 for 25 fines levied for various reasons, including failing to report campaign contributions, late filings and including incorrect information in his disclosures, according to election officials. The latest fine brings his total to $75,000.
Towns' largest fine came after campaign finance officials initiated an audit in 2010 that revealed he did not keep proper records. As a result, the state agency fined him $35,000. That was the second largest fine state officials had levied against a lawmaker, according Drew Rawlins, executive director of the Bureau of Ethics and Campaign Finance.
In 2007, then-Sen. Jerry Cooper was forced to pay $120,000 after an investigation found the McMinnville Democrat had used $95,000 in campaign money for personal use.
On Tuesday, Towns told The Tennessean he was hoping to be able to appeal the latest fine. When asked why he was not able to timely file his paperwork, Towns said it was due to personal reasons.
"It slipped through the cracks," Towns said, later adding, "life happens."
Towns said the fines he's faced in the past for late filings were "too high" while also calling campaign finance officials "out of control."
"They need to be looked at. They need to be reviewed," he said.