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Arrows, swashes, swooshes, globes, sunbursts and parallel, vertical and horizontal lines, words, letters, shapes and pictures. Logos are the most ubiquitous and essential of all graphic design devices, representing ideas, beliefs and, of course, things. They primarily identify products, businesses and institutions, but they are also associated, hopefully in a positive way, with the ethos or philosophy of those entities. The 50 logos in this book are examples of good ideas in the service of representation, reputation and identification.


text:
Martin Saggers
English cricketer
Martin John Saggers
(1972-05-23) 23 May 1972 (age 50)
King's Lynn, Norfolk
6 ft 2 in (1.88 m)
Right arm fast-medium
International information
National side
Test debut (cap 621)
29 October 2003 v Bangladesh
13 June 2004 v New Zealand
Domestic team information
Kent (squad no. 33)
Essex (loan)
Umpiring information
ODIs umpired
3 (2020–2022)
T20Is umpired
12 (2020–2022)
1 1,165 313 5
0.33 11.20 9.20 5.00
100s/50s
1 64 34* 5
Balls bowled
493 20,676 5,622 186
7 415 166 6
Bowling average
5 wickets in innings
10 wickets in match
2/29 7/79 5/22 2/14
Catches/stumpings
1/– 27/– 23/– 2/–
Source: Cricinfo, 3 August 2022
Martin John Saggers (born 23 May 1972) is an English county cricket umpire and a retired English cricketer.[1] He played international cricket for the England cricket team, including appearing in three Test matches and spent the majority of his first-class cricket career at Kent County Cricket Club. Saggers was born in King's Lynn in Norfolk.
Saggers had little success in his three seasons with Durham between 1996 and 1998, but then joined Kent and from 2000 to 2003 took more than 50 first-class wickets each year, his best being 83 in 2002. He also played for Essex on loan in 2007. He played for his native Norfolk in minor county matches in 1995–6.
Saggers made his Test match debut in 2003/04, as a replacement for the injured Andrew Flintoff in Dhaka, and also played in two of the three Tests against New Zealand the following summer. At Leeds he took the wicket of Mark Richardson with his first ball, but some wayward bowling and poor performances with the bat led to his being dropped for the games against West Indies.[2] With the bat, he scored 1, 0 and 0 in three innings, finishing his Test career with a batting average of 0.33.[3]
Saggers suffered a knee injury in August 2009, and a month later announced his retirement from professional cricket. Graham Johnson, Kent's chairman of cricket, paid tribute to Saggers, saying "We owe Martin a great deal, especially during a period when he was our seam attack. Quite rightly, on the basis of this success, he received recognition at International level. Always enthusiastic and positive during his career, he will carry these qualities into his plans for what follows after cricket".[2]
In 2012 Saggers became a full-time cricket umpire, standing in County Championship matches in England.[4][5]
In 2020, he was appointed to the ICC International Umpires' Panel. In January 2022, he was named as one of the on-field umpires for the 2022 ICC Under-19 Cricket World Cup in the West Indies.[6]
List of One Day International cricket umpires
List of Twenty20 International cricket umpires
^ "Late bloomers: Joe Denly joins England's list of 30-plus debutants". ESPN Cricinfo. Retrieved 30 January 2019.
^ a b Cricinfo staff (15 September 2009), Martin Saggers announces retirement, Cricinfo, retrieved 15 September 2009
^ "Was Dawid Malan's hundred the fastest for England in T20Is?". ESPN Cricinfo. Retrieved 12 November 2019.
^ Saggers promoted to full umpires list, CricInfo, 2011-11-11. Retrieved 2016-04-08.
^ Martin Saggers - from Test cricketer to first-class umpire, BBC Sport, 2012-02-29. Retrieved 2016-04-08.
^ "Match officials named for ICC U19 Men's Cricket World Cup". International Cricket Council. Retrieved 11 January 2022.
Martin Saggers at ESPNcricinfo
ICC International Panel of Umpires
Ahmed Shah Pakteen
Ahmad Shah Durrani
Bismillah Jan Shinwari
Izatullah Safi
S Craig
P Wilson
SJ Nogajski
GA Abood
Sharfuddoula
Masudur Rahman
Gazi Sohel
AG Wharf
DJ Millns
MJ Saggers
M Burns
J Madanagopal
AK Chaudhary
Virender Sharma
K. N. Ananthapadmanabhan
M Hawthorne
R Black
A Neill
PA Reynolds
WR Knights
CM Brown
SB Haig
Ahsan Raza
Faisal Khan Afridi
Asif Yaqoob
Rashid Riaz
S George
AT Holdstock
BP Jele
A Paleker
P Rambukwella
RSA Palliyaguruge
RR Wimalasiri
LE Hannibal
GO Brathwaite
N Duguid
L Reifer
P Gustard
L Rusere
I Chabi
C Phiri
F Mutizwa
ECB Umpires List
ICC Elite Panel
Gough
Illingworth
Kettleborough
ICC International Panel
Millns
Saggers
Bainton
Debenham
Llong
Mallender
O'Shaughnessy
Pollard
Shantry
Lungley
Middlebrook
Retrieved from "https://en.wikipedia.org/w/index.php?title=Martin_Saggers&oldid=1128917578"
Cricketers from King's Lynn
Durham cricketers
England Test cricketers
English cricket umpires
English cricketers
English One Day International cricket umpires
English Twenty20 International cricket umpires
Essex cricketers
Kent cricketers
Marylebone Cricket Club cricketers
Minor Counties cricketers
Norfolk cricketers
Use British English from March 2016

redpajama_set_name: RedPajamaCommonCrawl


A generalized approach to aging is possible based on the General System theory of aging, predicated on the General Model of aging. The fundamental cause of aging is the law of entropy increment in incompletely open systems. The major general mechanisms are: stochastic death of non-renewed structures; incomplete excretion of intoxicants; reduction of organism function regulation, self-renewal especially. Age-related syndromes and local manifestations of aging are secondary. Here, we review the progression of aging as development of multiple syndromes analogous to various diseases, that may allow physicians for prevention and for ease of diagnosis and treatment of common aging-related dysfunctions.
Fig. 1. Hierarchical structure of aging mechanisms.
The modern scientific principles of system analysis make it possible to apply methods of phenomenological analysis at an abstract level, replacing the consideration of the material system structure with the consideration of the essential inter-relations between its structural parts. Thus, the study of the endless particular manifestations and mechanisms is replaced by the consideration of the general laws and principles. The necessary and sufficient definition of "aging" must involve the general phenomenon of reducing viability (increasing the probability of death) with aging. This process is fatally determined by a fundamental law of nature – the second law of thermodynamics for semi-open systems (the law of increase of entropy in natural processes), which includes the general organism, comprising stable (or semi-stable) structures and elements. In Figure 1 we can see a hierarchical flow chart of the development of the aging process in a bio-system: from a single cause via the major mechanisms to specific manifestations of aging. Whereas the total cause of aging is manifested through three major aging mechanisms, the specific signs of aging are grouped by general mechanisms into the groups – syndromes.
4) the particular manifestations of aging.
The impacts on the natural aging syndromes may be much more effective. The syndrome description principle is one of the fundamentals of medicine and it is studied in detail in pathophysiology, where typical pathological processes are indicated. The body responds to any external and internal impacts, producing changes in its internal structures and functions, which are not unlimited, but are determined by a well-defined and limited number of standard reactions – or syndromes. These syndromes and the therapeutic interventions into them are well studied in medicine. Many of the syndromes are characteristic of natural aging and the physicians are well familiar with them.
It is becoming increasingly clear that well-known medical syndromes, which can be diagnosed and treated by common medical means, play an important role in the development of the natural aging process. Syndromes typical for common diseases are developed in the course of natural aging, including: dystrophy, hypoxia and tissue sclerosis, toxicity, oxidative stress, immunodeficiency, maladjustment, etc. Moreover, aging is accompanied by typical pathological processes or their precursor states: pre-diabetes, atherosclerosis, angina, tissue ischemia, osteoporosis, etc., requiring prevention and correction. This syndrome approach to influencing the natural aging processes, using the available well-known medical agents that can affect these syndromes, provides the physicians with a practical tool to actually impact on aging and makes such an impact feasible and necessary from the scientific, practical and regulatory points of view.
Natural aging as as a sequential poly-systemic syndrome.


text:
Environmental Toxicology of Trace Metals
Submit to Environments Review for Environments Edit a Special Issue
Environments Home
volume 8 7 6 5 4 3 2 1
issue 1 2 1 2 3 4 5 6 7 8 9 10 11 12 1 2 3 4 5 6 7 8 9 10 11 12 1 2 3 4 5 6 7 8 9 10 11 12 1 2 3 4 1 2 3 4 1 2 3 4 1 2
Special Issue "Environmental Toxicology of Trace Metals"
Print Special Issue Flyer
A special issue of Environments (ISSN 2076-3298).
Deadline for manuscript submissions: closed (30 June 2018).
Prof. Dr. Vera Slaveykova
University of Geneva, Faculty of Sciences, Earth and Environment Sciences, Department F.-A. Forel for Environmental and Aquatic Sciences, Environmental Biogeochemistry and Ecotoxicology, Uni Carl Vogt, 66 Bvd Carl-Vogt CH-1211 Geneva 4, Switzerland, Switzerland
Interests: aquatic toxicology of inorganic contaminants; chemical speciation and bioavailability; system ecotoxicology and adverse outcome pathways; chemical mixtures and combined stressor effects
Dr. Giulia Cheloni
Interests: multiple stressors and combined action of inorganic contaminants and environmental factors; toxicity of trace metals on aquatic primary producers and associated stress responses; trace metals effects across multiple levels of biological organization
Trace metals have a central role in the functioning of aquatic and terrestrial ecosystems. Both essential and toxic trace metals are involved in different chemical, biological, and physical processes that determine their concentration, speciation, reactivity, and impact on the biota. Despite the recognized hazard associated with the uncontrolled release of metals in the environment and the measures to reduce their input, metals remain an important threat to terrestrial and aquatic ecosystems. Several metals were included on the list of priority substances of environmental concern, while technology-critical metals such are rare-earth metals and platinum group metals emerge as contaminants. This Special Issue invites critical reviews and research papers providing innovative insights into trace metals in the aquatic and terrestrial environments from an ecotoxicology perspective.
The specific emphasis is on novel approaches in: (i) trace metals speciation and bioavailability assessment; (ii) biouptake and modes-of-action of trace metals; (iii) ecological effects at population and community levels; (iv) combined action of trace metals and environmental stressors; (v) ecotoxicological tools and models supporting environmental risk assessment for trace metals.
We particularly invite contributions concerning various aspects of the environmental toxicology of essential and toxic trace elements of global importance, data-poor and technology-critical elements in natural and engineered environments at different levels of biological organisation.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Environments is an international peer-reviewed open access monthly journal published by MDPI.
Chemical speciation and bioavailability
Toxicokinetic and toxicodynamic approaches
Modelling approaches
Environmental risk assessment
Adverse outcome pathways
Metal mixture effects
Metals and environmental stressors effects
Jump to: Research, Review
Open AccessEditorial
Preface: Special Issue on Environmental Toxicology of Trace Metals
Vera I. Slaveykova
Giulia Cheloni
Environments 2018, 5(12), 138; https://doi.org/10.3390/environments5120138 - 18 Dec 2018
Trace metals (TMs) have a central role in the functioning of aquatic and terrestrial ecosystems. [...] Full article
(This article belongs to the Special Issue Environmental Toxicology of Trace Metals)
Jump to: Editorial, Review
Spectroscopic and Voltammetric Analysis of Platinum Group Metals in Road Dust and Roadside Soil
Charlton Van der Horst
Bongiwe Silwana
Emmanuel Iwuoha
Vernon Somerset
Environments 2018, 5(11), 120; https://doi.org/10.3390/environments5110120 - 02 Nov 2018
The emission of toxic compounds by increasing anthropogenic activities affects human health and the environment. Heavy road traffic and mining activities are the major anthropogenic activities contributing to the presence of metals in the environment. The release of palladium (Pd), platinum (Pt), and [...] Read more.
The emission of toxic compounds by increasing anthropogenic activities affects human health and the environment. Heavy road traffic and mining activities are the major anthropogenic activities contributing to the presence of metals in the environment. The release of palladium (Pd), platinum (Pt), and rhodium (Rh) into the environment increases the levels of contamination in soils, road sediments, airborne particles, and plants. These Pd, Pt, and Rh in road dusts can be soluble and enter aquatic environment posing a risk to environment and human health. The aim of this study is to determine the levels of Pd, Pt, and Rh with spectroscopy and voltammetric methods. Potential interferences by other metal ions (Na(I), Fe(III), Ni(II), Co(II)) in voltammetric methods have also been investigated in this study. At all the sampling sites very low concentrations of Pd, Pt, and Rh were found at levels that range from 0.48 ± 0.05 to 5.44 ± 0.11 ng/g (dry weight (d.wt)) for Pd(II), with 17.28 ± 3.12 to 81.44 ± 3.07 pg/g (d.wt) for Pt(II), and 14.34 ± 3.08 to 53.35 ± 4.07 pg/g (d.wt) for Rh(III). The instrumental limit of detection for Pd, Pt, and Rh for Inductively Coupled Plasma Quadrupole-based Mass Spectrometry (ICP-QMS) analysis was found to be 3 × 10−6 µg/g, 3 × 10−6 µg/g and 1 × 10−6 µg/g, respectively. In the case of voltammetric analysis the instrumental limit of detection for Pd(II), Pt(II), and Rh(III) for differential pulse adsorptive stripping voltammetry was found to be 7 × 10−8 µg/g, 6 × 10−8 µg/g, and 2 × 10−7 µg/g, respectively. For the sensor application, good precision was obtained due to consistently reproduced the measurements with a reproducibility of 6.31% for Pt(II), 7.58% for Pd(II), and 5.37% for Rh(III) (n = 10). The reproducibility for ICP-QMS analysis were 1.58% for Pd(II), 1.12% for Pt(II), and 1.37% for Rh(III) (n = 5). In the case of repeatability for differential pulse adsorptive stripping voltammetry (DPAdSV) and ICP-QMS, good standard deviations of 0.01 for Pd(II); 0.02 for Pt(II), 0.009 for Rh(III) and 0.011 for Pd, 0.019 for Pt and 0.013 for Rh, respectively. Full article
Voltammetric and Spectroscopic Determination of Rare Earth Elements in Fresh and Surface Water Samples
Martin Makombe
Environments 2018, 5(10), 112; https://doi.org/10.3390/environments5100112 - 09 Oct 2018
The increasing demand for rare earth elements in green technology, electronic components, petroleum refining, and agricultural activities has resulted in their scattering and accumulation in the environment. This study determined cerium, lanthanum and praseodymium in environmental water samples with the help of adsorptive [...] Read more.
The increasing demand for rare earth elements in green technology, electronic components, petroleum refining, and agricultural activities has resulted in their scattering and accumulation in the environment. This study determined cerium, lanthanum and praseodymium in environmental water samples with the help of adsorptive differential pulse stripping voltammetry (AdDPSV) and inductive coupled plasma-optical emission spectroscopy (ICP-OES). A comparison of the results of these two analytical techniques was also made. The accuracy and precision of the methods were evaluated by spiking water samples with a known amount of REEs. The detection limit obtained for the stripping analysis was 0.10 μg/L for Ce(III), and 2.10 μg/L for combined La(III) and Pr(III). The spectroscopic method of determination by ICP-OES was applied to the same samples to evaluate the effectiveness of the voltammetry procedure. The ICP-OES detection limit obtained was 2.45, 3.12 and 3.90 μg/L for Ce(III), La(III) and Pr(III), respectively. The results obtained from the two techniques showed low detection limits in voltammetry; the ICP-OES method achieved better simultaneous analysis. This sensor has been successfully applied for the determination of cerium, lanthanum, and praseodymium in environmental water samples, offering good results. Full article
Cytosolic Distribution of Metals (Cd, Cu) and Metalloids (As, Se) in Livers and Gonads of Field-Collected Fish Exposed to an Environmental Contamination Gradient: An SEC-ICP-MS Analysis
Nastassia Urien
Sabrina Jacob
Patrice Couture
Peter G. C. Campbell
Environments 2018, 5(9), 102; https://doi.org/10.3390/environments5090102 - 05 Sep 2018
The distribution of As, Cd, Cu and Se among biomolecules of different molecular weight (MW) in the heat-treated cytosolic fraction of livers and gonads of white suckers (WS; Catostomus commersonii) collected in a reference lake and in a lake subject to multi-metal [...] Read more.
The distribution of As, Cd, Cu and Se among biomolecules of different molecular weight (MW) in the heat-treated cytosolic fraction of livers and gonads of white suckers (WS; Catostomus commersonii) collected in a reference lake and in a lake subject to multi-metal contamination was investigated. Distribution profiles were obtained by separation of the heat-stable protein and peptide (HSP) fractions using size-exclusion high performance-liquid chromatography, coupled online to an inductively coupled plasma mass spectrometer, to quantify the associated metals. Metal-handling strategies did not vary between the reference and exposed fish, with the exception of As. Cadmium and Cu appeared associated with the heat-stable peptides metallothioneins (MTs), indicating their reasonable detoxification and regulation in WS. In contrast, Se and As were not bound to MTs, but rather, to biomolecules of lower MW (<2 kDa). Arsenic was found associated with the same biomolecules in fish from both lakes, but their proportions changed between reference and exposed fish. For future work, the identification of the Se and As binding biomolecules would be of great interest to determine if these metalloids are detoxified or if, conversely, the biomolecules are metal-sensitive and their binding to Se or As represents a threat for the health of these fish. Full article
Ratio of Mercury Concentration to PCB Concentration Varies with Sex of White Sucker (Catostomus commersonii)
Charles P. Madenjian
Andrew L. Stevens
Martin A. Stapanian
David P. Krabbenhoft
John F. DeWild
Jacob M. Ogorek
William H. Edwards
Lynn M. Ogilvie
Peter B. McIntyre
Environments 2018, 5(9), 94; https://doi.org/10.3390/environments5090094 - 24 Aug 2018
The whole-fish total mercury (Hg) concentrations were determined in 25 mature female and 26 mature male white suckers (Catostomus commersonii) caught during their spawning run in the Kewaunee River, a tributary to Lake Michigan. The age of each fish was estimated [...] Read more.
The whole-fish total mercury (Hg) concentrations were determined in 25 mature female and 26 mature male white suckers (Catostomus commersonii) caught during their spawning run in the Kewaunee River, a tributary to Lake Michigan. The age of each fish was estimated using thin-sectioned otoliths, and total length (TL) and weight were determined for each fish. When adjusted for the effect of age, males were found to be 7% higher in Hg concentration than females. Nearly all (about 98%) of the Hg found in the white suckers was determined to be methylmercury. In an earlier study on the same 51 white suckers from the Kewaunee River spawning run, males were found to be 18% higher than females in polychlorinated biphenyl (PCB) concentration. We determined that the ratio of Hg concentration to PCB concentration in females was significantly higher than that in males. Thus, sex significantly interacted with contaminant type (Hg or PCBs) in determining contaminant concentrations. The most plausible explanation for this interaction was that males eliminated Hg at a faster rate than females, most likely due to the boosting of the Hg-elimination rate by certain androgens such as testosterone and 11-ketotestosterone. Hg concentrations in the white suckers were well below federal guidelines for fish consumption. Full article
Pronounced Antagonism of Zinc and Arsenate on Toxicity to Barley Root Elongation in Soil
Georgina Guzman-Rangel
Daniela Montalvo
Erik Smolders
Environments 2018, 5(7), 83; https://doi.org/10.3390/environments5070083 - 17 Jul 2018
Zinc (Zn) and arsenic (As) occur as mixed contaminants in soil and the interactions between them remain unclear. Here, we investigated a Zn2+ and H2AsO4− mixture interaction and their effects on plant growth. Three different soils were spiked [...] Read more.
Zinc (Zn) and arsenic (As) occur as mixed contaminants in soil and the interactions between them remain unclear. Here, we investigated a Zn2+ and H2AsO4− mixture interaction and their effects on plant growth. Three different soils were spiked with ZnCl2 and NaH2AsO4, each dosed singly or in combination. The soils were leached to remove excessive salt and were aged (>7 days), before toxicity testing using a 5-day root elongation of barley (Hordeum vulgare L.). In the single treatments, the 50% inhibitory effect concentrations in the soil (EC50, total measured concentration) were 2000–3800 mg Zn kg−1 and 96–620 mg As kg−1, depending on the soils. The mixture analyses based on the total concentrations showed overall and significant Zn–As antagonism in two soils, either based on the concentration addition (CA) or independent action (IA) model, whereas no significant interactions (either CA or IA) were found in one soil, which had the lowest content of Fe-oxides. The soil solution composition showed a decreased As concentration upon the addition of ZnCl2 at an equal soil As total concentration; however, the reverse was not found, in line with the cation–anion electrostatic interaction or formation of ternary surface complexes on Fe-oxides. The data revealed that the Zn–As antagonisms (total concentrations) are partially related to the increased Zn immobilizing As in soil. Full article
Characterization of Landfill Leachates and Sediments in Major Cities of Indochina Peninsular Countries—Heavy Metal Partitioning in Municipal Solid Waste Leachate
Phetyasone Xaypanya
Jiro Takemura
Chart Chiemchaisri
Hul Seingheng
Maria Antonia N. Tanchuling
Environments 2018, 5(6), 65; https://doi.org/10.3390/environments5060065 - 03 Jun 2018
In this study, leachate and sediment samples were collected from the leachate drains, ponds and waste pits of three landfills in the Indochina peninsula to investigate the level of contamination of biochemical parameters, especially heavy metals. In-situ and laboratory measurements were conducted, together [...] Read more.
In this study, leachate and sediment samples were collected from the leachate drains, ponds and waste pits of three landfills in the Indochina peninsula to investigate the level of contamination of biochemical parameters, especially heavy metals. In-situ and laboratory measurements were conducted, together with site surveys to discuss the effects of site characteristics on leachate qualities. It was confirmed from the investigation that the changes in leachate qualities are mainly caused by the landfill site conditions, e.g., soil cover, the waste compaction level, waste thickness, dumping method, and leachate storage, and that these conditions lead to different levels of dilution and biochemical reaction of the leachate. Most of the biochemical parameters of the fresh leachates were greater than the effluent standards, and showed higher concentrations than those measured for the leachate in large storage ponds. The concentrations of the parameters were higher in the dry season than the wet season for all fresh leachate samples, but no significant seasonal difference was observed in the large leachate storage ponds. The majority of heavy metals were partitioned in the suspended solids, and no clear seasonal change of heavy metal contents was contained in the suspended solids and sediment samples. Full article
Figure 11 Cont.
Trace Metal Modelling of a Complex River Basin Using the Suite of Models Integrated in the OpenMI Platform
Narayan Kumar Shrestha
Chrismar Punzal
Olkeba Tolessa Leta
Willy Bauwens
Environments 2018, 5(4), 48; https://doi.org/10.3390/environments5040048 - 13 Apr 2018
Modelling trace metal dynamics is essential in an integrated modelling framework as trace metals have the potential to be fatal, even when present at low concentrations. Since the degree of bioavailability of a metal depends on its presence in the dissolved phase, it [...] Read more.
Modelling trace metal dynamics is essential in an integrated modelling framework as trace metals have the potential to be fatal, even when present at low concentrations. Since the degree of bioavailability of a metal depends on its presence in the dissolved phase, it is necessary to keep track of both the dissolved and particulate phase of metals. In general, the well-known partitioning coefficient approach is widely used for trace metal speciation. As such, we applied a parametric approach to relate the partitioning coefficient to several environmental variables. These environmental variables are made available by a suite of physically based models (a hydrologic and diffuse pollution model, Soil and Water Assessment Tool (SWAT); a hydraulic model, Storm Water Management Model (SWMM); a stream temperature model; an in-stream water quality conversion model; and a sediment transport model) integrated using the Open Modelling Interface (OpenMI). For trace metal speciation, two regression techniques, (a) the multi-linear regression (MLR) and (b) the principle component regression (PCR), were used. It is then tested in the Zenne river basin, Belgium, to simulate four trace metals (copper, cadmium, zinc and lead) dynamics. We demonstrated the usefulness of the OpenMI platform to link different model components for integrated trace metal transport modelling of a complex river basin. It was found that the integrated model simulated different metals with 'satisfactory' accuracy. The MLR- and PCR-based model results were also comparable. From a management perspective, the river is not heavily polluted except for the level of dissolved zinc. We believe that the availability of such a model will allow for a better understanding of trace metal dynamics, which could be utilized to improve the present condition of the river. Full article
Supplementary File 1 (XLSX, 15 KiB)
Freshwater Diatoms as Indicators of Combined Long-Term Mining and Urban Stressors in Junction Creek (Ontario, Canada)
Soizic Morin
Vincent Laderriere
Environments 2018, 5(2), 30; https://doi.org/10.3390/environments5020030 - 21 Feb 2018
Sudbury (Ontario, Canada) has a long mining history that has left the region with a distinctive legacy of environmental impacts. Several actions have been undertaken since the 1970s to rehabilitate this deteriorated environment, in both terrestrial and aquatic ecosystems. Despite a marked increase [...] Read more.
Sudbury (Ontario, Canada) has a long mining history that has left the region with a distinctive legacy of environmental impacts. Several actions have been undertaken since the 1970s to rehabilitate this deteriorated environment, in both terrestrial and aquatic ecosystems. Despite a marked increase in environmental health, we show that the Junction Creek system remains under multiple stressors from present and past mining operations, and from urban-related pressures such as municipal wastewater treatment plants, golf courses and stormwater runoff. Water samples have elevated metal concentrations, with values reaching up to 1 mg·L−1 Ni, 40 μg·L−1 Zn, and 0.5 μg·L−1 Cd. The responses of diatoms to stressors were observed at the assemblage level (metal tolerant species, nutrient-loving species), and at the individual level through the presence of teratologies (abnormal diatom frustules). The cumulative criterion unit (CCU) approach was used as a proxy for metal toxicity to aquatic life and suggested elevated potential for toxicity at certain sites. Diatom teratologies were significantly less frequent at sites with CCU values <1, suggesting "background" metal concentrations as compared to sites with higher CCU values. The highest percentages of teratologies were observed at sites presenting multiple types of environmental pressures. Full article
Jump to: Editorial, Research
Combined Effects of Trace Metals and Light on Photosynthetic Microorganisms in Aquatic Environment
In the present review, we critically examine the state-of-the-art of the research on combined effects of trace metals and light on photosynthetic microorganisms in aquatic environment. Light of different intensity and spectral composition affects the interactions between trace metals and photosynthetic microorganisms directly, [...] Read more.
In the present review, we critically examine the state-of-the-art of the research on combined effects of trace metals and light on photosynthetic microorganisms in aquatic environment. Light of different intensity and spectral composition affects the interactions between trace metals and photosynthetic microorganisms directly, by affecting vital cellular functions and metal toxicokinetics and toxicodynamics, and indirectly, by changing ambient medium characteristics. Light radiation and in particular, the ultraviolet radiation component (UVR) alters the structure and reactivity of dissolved organic matter in natural water, which in most of the cases decreases its metal binding capacity and enhances metal bioavailability. The increase of cellular metal concentrations is generally associated with increasing light intensity, however further studies are necessary to better understand the underlying mechanisms. Studies on the combined exposures of photosynthetic microorganisms to metals and UVR reveal antagonistic, additive or synergistic interactions depending on light intensity, spectral composition or light pre-exposure history. Among the light spectrum components, most of the research was performed with UVR, while the knowledge on the role of high-intensity visible light and environmentally relevant solar light radiation is still limited. The extent of combined effects also depends on the exposure sequence and duration, as well as the species-specific sensitivity of the tested microorganisms and the activation of stress defense responses. Full article
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text:
With the inception of MIST, Science and Humanities Department has started its journey from 19 April 1998. Since the beginning, this department has been working as an essential component of the statutory framework of MIST. This department is committed to providing the students of MIST with required knowledge in the fields of Mathematics, Physics, Chemistry, English, Economics, Sociology and Accounting. Drawing upon the most recent thinking in the creative world each subject considers theoretical exposure, examines existing realities, includes essential elements, and offers a concise but indispensable portion of knowledge in that field to enrich the students and to make them oriented with world of learning. Thus this department is playing its due role in producing competent engineers, architects and planners who in practical life prove themselves successful and efficient. As a multidisciplinary department it aims at developing in the students those faculties which help them to orient themselves in this predominantly technological world with more social adaptability. We are committed to turn this institution as the centre of excellence and to uphold the image of this premier engineering outfit in the days to come.
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text:
Dusty Springfield - 80th Birthday Remembrance - 16th April 1939
Thread: Dusty Springfield - 80th Birthday Remembrance - 16th April 1939
OK, so not a Motown artist. However in the UK Dusty was a huge fan and supporter of Motown culminating in the Ready Steady Go! 1965 special featuring Supremes, Miracles, Temptations and Martha with whom she sang 'Wishin' & Hopin''. She recorded and performed many Motown songs with her favourite being 'Ain't No Mountain High Enough'. In 1966 she asked Val & Nick if she could have it but was refused as they said that they needed it for a Motown artist. Sadly she never did record it. Today 16th April 2019 Dusty would have been 80. She was arguably the best female singer to come out of the UK. Here are just a few of her songs.
sophisticated_soul
Thank you very much for this, Copley!
I had the Ready Steady Go video....it was an early B&W time capsule masterpiece! Everyone was so young...and the finale of the entire cast doing Mickey's Monkey remains one of my all time fav clips.
Dusty was also fond of Euro composers....some of her songs were the first English language versions I believe....my personal DS favs are Little By Little, I Close My Eye's and Count to Ten, All I See is You...and of course she owns Son of A Preacher Man. (Ike and Tina's version on the 'IN PERSON' LP comes close, and they next do a credible version of Grapevine)
Bluebrock
Originally Posted by copley
Thank you for that. Dusty was one of the finest female vocalists i have ever heard. Her voice was so rich and full of emotion. She could really bring a song to life. It is such a pity that Dusty was so hard on herself. She found it difficult to find true happiness and contentment in her life. She could be very difficult, and she could also be very caring and considerate. we will never forget her. R.I.P.
reachoutuk
Hi Copley, and thank you for your timely reminder. Nice to see someone else who loves her music. By coincidence, I have only just finished reading a biography about her written by Lucy O'Brien which I had bought years ago.
2 March this year was the 20th anniversary of her passing, the same day I believe she was due to receive her OBE. (I stand to be corrected if I'm wrong). This anniversary also gave me a chance to work my way through my entire collection of her recordings, and to add three additional CDs to fill in some gaps.
Somewhere in my archives, I still have VHS tapes of the Ready Steady Go! programmes repeated sometime in the 1980s and I must get round to transferring them to DVD before my equipment fails. Amongst them is the episode mentioned by "gman" with Dusty introducing the Motown artists and singing along with them.
R.I.P. Dusty from one of your life-long fans who bought, and still possess, your first solo single back in late-1963.
Has anyone purchased the mono vinyl reissues of Dusty's first three American albums on the Premium Cool label? Her masters situation seems to be murky (we are sooooo lucky as Motown fans to have reissues of original hit mixes from mastertapes), which makes me wonder about the sound on these LPs. I've read one or two positive reviews but nothing detailed.
https://www.amazon.com/Stay-Awhile-O...dp/B017PPG538/
https://www.amazon.com/Dusty-180-Gram-Mono-Springfield/dp/B017PPXFO0/
https://www.amazon.com/Ooooooweeee-G...dp/B072HJNF3Q/
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A 10KM Multi Terrain race for seniors that takes place along the scenic cliff tops of the South Shields coastline finishing on the track at Gypsies Green. The Junior is shorter at 1km and 3km depending on age. Numbers are collected on the day from 9am.


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Stages & tech specs
Vladislav Delay & AGF + Digge Shim
Bombastic AV-show with two legends of electronica
On the turn of the millenia, electronica as a genre experienced it's defining era.
This period wouldn't be the same without Vladislav Delay. The Finnish musician's minimal, glitch-infused releases on labels such as Raster-Noton and Sigma Editions was genre-defining. Together with his more dubby releases on the Basic Channel sublabel Chain Reaction, these releases have also defined his own artistry as a whole.
His career spans over three decades and has contained collaborations with legendary artists such as Ryuichi Sakamoto, Massive Attack, Mika Vainio and Moritz Von Oswald. If you think this sounds a bit dated, please note what we wrote in the sentence above: Three decades(!). Unlike some of his peers, Vladislav Delay has been in constant movement and during the pandemic alone, he's released no less than two studio albums.
Sasu Ripatti, the man behind the pseudonym, sometimes mentions his background as a jazz drummer as defining for his musical expression. In his last albums "Rakka" (2020) and "Rakka ll" (2021), we are invited to take part in his equilibrist and unique sense of polyrhythmics, timing and texture, infused with hints of his rich world of sound, past and present.
AGF is a sound sculptress, musician, poet and visual artist. Born in the GDR and with a career that would make anyone feel inferior, she is Vladislav's longtime partner and artistic collaborateur.
She's played solo shows at festivals such as Ars Electronica, Sonár, CTM and Sonic Acts and at venues such as Pompidue in Paris, ICC Tokyo and Akadamie der Künste in Berlin. She's also collaborated with legendary artists such as Eliane Radigue and Craig Armstrong.
Taking off in Vladislav Delay's two last albums, she creates a unique, rich textured AV-piece that will make the Black Box shiver.
Before you enter the Black Box, local electro producer, label honcho and Bolero record shop owner will grace us with an ambient live performance, specially composed for this very occasion. Frequently known as Dip Shim, tonight known as Digge Shim.
Doors 20.00, On stage 20.30
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What restaurants are inside or nearby UAB Hospital?
UAB Hospital offers inpatients hotel-style room service. Dining is available for families and other visitors in several different venues, including a Food Court and a Starbucks on the second floor of the North Pavilion, and GG's Starbuck's Coffee Cart on the first floor of the West Pavilion, Food Trucks outside the North Pavilion Lobby, and on the third floor of UAB Hospital Highlands. Many retail eateries surround UAB, including several in the street-level retail spaces of the Fourth Avenue Parking Deck. For a list of nearby restaurants or for questions about specific restaurants, call Guest Services by dialing *55 from any hospital telephone or 205-934-2273.
(Featuring Boar's Head Meats) Monday-Friday, 11 a.m.-2 p.m.
Pizza Monday-Friday, 11 a.m.-2 p.m.
(Meat & Three) Monday-Friday, 6-9:45 a.m., 11 a.m.-2 p.m., 5-7:30 p.m.
World of Flavors Monday-Friday, 11 a.m.-2 p.m.
(Grill & More) 7 days a week, 6-9:45 a.m., 11 a.m.-7:30 p.m.
Salad Bar Monday-Friday, 11 a.m.-7:30 p.m.
Sushi Monday-Friday, 11 a.m.-2 p.m.
Vending machines are located throughout the facility for around-the-clock food and beverage options.
Birmingham also offers many fine dining options close to UAB Hospital. There are many dining options available within UAB Hospital, but we are glad to provide a list of and directions to dining options outside of the medical center campus. Speak with a member of our guest services team or dial *55 from any phone to be connected.


The firm will issue the grades on Wednesday - they will be the first cryptocurrencies ratings from an established agency.
Wall Street could not ignore the volatile, yet soaring, cryptocurrency market for long. And the wait for recognition seems to be over as asset rating agency Weiss Ratings recently announced that it is going to issue grades for dozens of cryptocurrencies.
The firm will release the ratings on the 24th of January. They will include market leader Bitcoin along with a series of altcoins like Ethereum, Ripple, Bitcoin Cash, Cardano, NEM, Litecoin, Stellar, EOS, IOTA, Dash, NEO, TRON, Monero, Bitcoin Gold, and many more.
Even though cryptocurrencies are attracting a lot of investors, most of them are indulging in speculative trading. Lately, many established consulting and trading firms have been recommending cryptocurrency to their clients to invest in – but none of the established asset rating agencies have rated the booming coins like a normal stock.
The cryptocurrency market is still a very controversial one. The entire crypto economy is now worth more than half a trillion dollars, but the market is unregulated worldwide. The core structure of blockchain technology is making it very tough for authorities to impose regulations like they do on the traditional stock market.
"We're proud to be the first to bring that benefit to investors — to help them cut through the hype and identify the few truly solid cryptocurrencies. Our ratings are based on hard data and objective analysis. But they're bound to create controversy, including some grades that may come as a surprise to some people," Mr. Weiss added.
Last month, Bitcoin made its debut on the mainstream stock market as two leading US exchanges listed Bitcoin futures on their platform. This development also boosted volatile coin prices, and most of them broke all previous records. However this did not last long, as prices have gone down significantly over the past couple of weeks.
Many parties are also pushing for the introduction of Bitcoin ETFs in the mainstream market, but they are facing regulatory hurdles and most of them have pulled their proposals back.
Now, it will be very interesting to see how the introduction of grades by a reputed agency will affect the market. This might demonstrate legitimacy to sceptics who are adamant that the entire crypto economy is a bubble.


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Maine, Maine smaller cities, Maine smallest towns
Cumberland County, ME
Cumberland County, Maine (ME)
County population in 2019: 295,003 (64% urban, 36% rural); it was 265,612 in 2000
County owner-occupied with a mortgage or a loan houses and condos in 2010: 58,138
County owner-occupied free and clear houses and condos in 2010: 20,407
County owner-occupied houses and condos in 2000: 72,066
Renter-occupied apartments: 38,794 (it was 35,923 in 2000)
Land area: 836 sq. mi.
Water area: 381.4 sq. mi.
Population density: 353 people per square mile (high).
March 2019 cost of living index in Cumberland County: 101.6 (near average, U.S. average is 100)
Industries providing employment: Educational, health and social services (28.7%), Professional, scientific, management, administrative, and waste management services (13.3%), Retail trade (11.3%).
Type of workers:
Private wage or salary: 82%
Government: 11%
Self-employed, not incorporated: 6%
Unpaid family work: 0%
265,12289.9%White Non-Hispanic Alone
9,3403.2%Black Non-Hispanic Alone
6,5432.2%Asian alone
6,3672.2%Hispanic or Latino
5,9632.0%Two or more races
8700.3%American Indian and Alaska Native alone
7680.3%Some other race alone
300.01%Native Hawaiian and Other
Pacific Islander alone
Maine median age:
Males: 142,222 (48.2%)
Females: 152,781 (51.8%)
Recent posts about Cumberland County, Maine on our local forum with over 2,200,000 registered users. Cumberland County is mentioned 41 times on our forum:
Best towns to live in near USM? (5 replies)
Moving to Maine in October...Safe & Affordable near Portland (10 replies)
Considering moving to Maine, but Gov. LePage scares me..... (166 replies)
Returning to Maine after 15 years away... (5 replies)
Is Southern Maine "Family Friendly"? (90 replies)
Portland Violence (33 replies)
Cumberland County:
Maine:
Estimated median household income in 2019: $76,059 ($44,048 in 1999)
Median contract rent in 2019 for apartments: $1,086 (lower quartile is $758, upper quartile is $1,436)
Cumberland:
Lower value quartile - upper value quartile: $216,900 - $425,000
Townhouses or other attached units: $393,629
In 2-unit structures: $334,691
In 3-to-4-unit structures: $352,811
In 5-or-more-unit structures: $299,492
Median monthly housing costs for homes and condos with a mortgage: $1,761
Median monthly housing costs for units without a mortgage: $695
Institutionalized population: 3,057
Crime in 2005 (reported by the sheriff's office or county police, not the county total):
Murders: 0
Rapes: 9
Robberies: 5
Assaults: 28
Burglaries: 234
Thefts: 301
Auto thefts: 45
Health of residents in Cumberland County based on CDC Behavioral Risk Factor Surveillance System Survey Questionnaires from 2013 to 2019:
General health status score of residents in this county from 1 (poor) to 5 (excellent) is 3.6. This is better than average.
77.1% of residents exercised in the past month. This is about average.
47.8% of residents smoked 100+ cigarettes in their lives. This is about average.
63.5% of adult residents drank alcohol in the past 30 days. This is less than average.
73.5% of residents visited a dentist within the past year. This is about average.
Average weight of males is 195 pounds. This is about average.
Average weight of females is 159 pounds. This is about average.
General health status score of residents in this county from 1 (poor) to 5 (excellent) is 3.7. This is significantly better than average.
81.9% of residents exercised in the past month. This is more than average.
79.3% of adult residents drank alcohol in the past 30 days. This is about average.
77.7% of residents visited a dentist within the past year. This is more than average.
24.5% of residents keep firearms around their homes. This is about average.
Single-family new house construction building permits:
1997: 1086 buildings, average cost: $122,400
2007: 963 buildings, average cost: $217,600
(6.2% for White Non-Hispanic residents, 33.9% for Black residents, 8.3% for Hispanic or Latino residents, 10.1% for American Indian residents, 2.8% for other race residents, 13.5% for two or more races residents)
Median age of residents in 2019: 42.5 years old
(Males: 41.2 years old, Females: 43.7 years old)
(Median age for: White residents: 44.3 years old, Black residents: 26.8 years old, American Indian residents: 45.4 years old, Asian residents: 39.7 years old, Hispanic or Latino residents: 29.0 years old, Other race residents: 16.3 years old)
Area name: Cumberland County, ME (part) HUD Metro FMR Area
Fair market rent in 2006 for a 1-bedroom apartment in Cumberland County is $570 a month.
Fair market rent for a 2-bedroom apartment is $735 a month.
Cities in this county include: Portland, South Portland, Westbrook, Windham, Brunswick, Falmouth, Standish, Cape Elizabeth, Cumberland, Gray.
Cumberland County has a predicted average indoor radon screening level greater than 4 pCi/L (pico curies per liter) - Highest Potential
2018 air pollution in Cumberland County:
Carbon Monoxide: 0.181 ppm (standard limit: 9 ppm). Near U.S. average.
Nitrogen Dioxide: 0.01 ppm (standard limit: 0.053 ppm). Near U.S. average.
Ozone (1-hour): 0.030 ppm (standard limit: 0.12 ppm). Near U.S. average.
Particulate Matter (PM2.5) Annual: 7.0 µg/m3(standard limit: 15.0 µg/m3). Near U.S. average.
Sulfur Oxides Annual: 0.001 ppm (standard limit: 0.03 ppm). Near U.S. average.
Local government website: www.cumberlandcounty.org/cntygovt.html
Click to draw/clear Cumberland County borders
Neighboring counties: Bay County, Michigan , Rutland County, Vermont , Waldo County , Linn County, Oregon , Lewis County, New York .
Current college students: 16,414
People 25 years of age or older with a high school degree or higher: 94.9%
People 25 years of age or older with a bachelor's degree or higher: 50.1%
Number of foreign born residents: 19,692 (53.9% naturalized citizens)
7,6912010 or later
3,5922000 to 2009
3,130Before 1970
Percentage of county residents living and working in this county: 88.7%
One, detached: 96,018
One, attached: 6,532
Two: 7,902
3 or 4: 10,358
5 to 9: 7,727
10 to 19: 2,307
50 or more: 5,571
Mobile homes: 6,238
Boats, RVs, vans, etc.: 207
Housing units in Cumberland County with a mortgage: 57,799 (890 second mortgage, 7,156 home equity loan, 49 both second mortgage and home equity loan)
Houses without a mortgage: 30,116
65.5% with mortgage
Religion statistics for Cumberland County
Catholic 38,243 19
Other 7,187 44
Orthodox 500 1
Black Protestant 285 2
Cumberland County Religion Details
Source: Clifford Grammich, Kirk Hadaway, Richard Houseal, Dale E.Jones, Alexei Krindatch, Richie Stanley and Richard H.Taylor. 2012. 2010 U.S.Religion Census: Religious Congregations & Membership Study. Association of Statisticians of American Religious Bodies. Jones, Dale E., et al. 2002. Congregations and Membership in the United States 2000. Nashville, TN: Glenmary Research Center.
Number of convenience stores (with gas): 105
12.01 / 10,000 pop.
Agriculture in Cumberland County:
Average size of farms: 91 acres
Average value of agricultural products sold per farm: $29,519
Average value of crops sold per acre for harvested cropland: $768.52
The value of livestock, poultry, and their products as a percentage of the total market value of agricultural products sold: 33.11%
Average total farm production expenses per farm: $34,717
Harvested cropland as a percentage of land in farms: 28.12%
Irrigated harvested cropland as a percentage of land in farms: 4.56%
Average market value of all machinery and equipment per farm: $45,387
The percentage of farms operated by a family or individual: 84.06%
Average age of principal farm operators: 53 years
Average number of cattle and calves per 100 acres of all land in farms: 7.37
Milk cows as a percentage of all cattle and calves: 26.02%
Vegetables: 538 harvested acres
Land in orchards: 285 acres
Cumberland County-area historical earthquake activity is significantly above Maine state average. It is 75% smaller than the overall U.S. average.
On 10/16/2012 at 23:12:25, a magnitude 4.7 (4.7 ML, Depth: 10.0 mi, Class: Light, Intensity: IV - V) earthquake occurred 20.9 miles away from Cumberland County center
On 4/20/2002 at 10:50:47, a magnitude 5.3 (5.3 ML, Depth: 3.0 mi, Class: Moderate, Intensity: VI - VII) earthquake occurred 174.6 miles away from the county center
On 1/19/1982 at 00:14:42, a magnitude 4.7 (4.5 MB, 4.7 MD, 4.5 LG) earthquake occurred 66.6 miles away from the county center
On 4/20/2002 at 10:50:47, a magnitude 5.2 (5.2 MB, 4.2 MS, 5.2 MW, 5.0 MW) earthquake occurred 175.1 miles away from the county center
On 10/7/1983 at 10:18:46, a magnitude 5.3 (5.1 MB, 5.3 LG, 5.1 ML) earthquake occurred 200.5 miles away from Cumberland County center
On 8/21/1996 at 07:54:14, a magnitude 3.8 (3.8 LG, 3.6 LG, Depth: 6.2 mi, Class: Light, Intensity: II - III) earthquake occurred 58.0 miles away from the county center
Magnitude types: regional Lg-wave magnitude (LG), body-wave magnitude (MB), duration magnitude (MD), local magnitude (ML), surface-wave magnitude (MS), moment magnitude (MW)
Most recent natural disasters:
Maine Covid-19 Pandemic, Incident Period: January 20, 2020, Major Disaster (Presidential) Declared DR-4522-ME: April 4, 2020, FEMA Id: 4522, Natural disaster type: Other
Maine Severe Storm And Flooding, Incident Period: October 29, 2017 - November 1, 2017, FEMA Id: 4354, Natural disaster type: Storm, Flood
Maine Severe Winter Storm, Snowstorm, and Flooding, Incident Period: January 26, 2015 to January 29, 2015, Major Disaster (Presidential) Declared DR-4208: March 12, 2015, FEMA Id: 4208, Natural disaster type: Snowstorm, Winter Storm, Flood
Maine Winter Storm, Snow Storm, Flooding, Incident Period: February 08, 2013 to February 10, 2013, Major Disaster (Presidential) Declared DR-4108: March 25, 2013, FEMA Id: 4108, Natural disaster type: Winter Storm, Storm, Flood, Snow
Maine Severe Winter Storms and Flooding, Incident Period: February 23, 2010 to March 02, 2010, Major Disaster (Presidential) Declared DR-1891: March 25, 2010, FEMA Id: 1891, Natural disaster type: Winter Storm, Flood
Maine Severe Winter Storm, Incident Period: December 11, 2008 to December 29, 2008, Emergency Declared EM-3298: December 15, 2008, FEMA Id: 3298, Natural disaster type: Winter Storm
Maine Severe Winter Storm and Flooding, Incident Period: December 11, 2008 to December 29, 2008, Major Disaster (Presidential) Declared DR-1815: January 09, 2009, FEMA Id: 1815, Natural disaster type: Winter Storm, Flood
Maine Severe Storms, Flooding, and Tornadoes, Incident Period: July 18, 2008 to August 16, 2008, Major Disaster (Presidential) Declared DR-1788: September 09, 2008, FEMA Id: 1788, Natural disaster type: Storm, Tornado, Flood
Maine Severe Storms and Inland and Coastal Flooding, Incident Period: April 15, 2007 to April 23, 2007, Major Disaster (Presidential) Declared DR-1693: April 25, 2007, FEMA Id: 1693, Natural disaster type: Storm, Flood
Maine Hurricane Katrina Evacuation, Incident Period: August 29, 2005 to October 01, 2005, Emergency Declared EM-3256: September 19, 2005, FEMA Id: 3256, Natural disaster type: Hurricane
23 other natural disasters have been reported since 1953.
The number of natural disasters in Cumberland County (33) is a lot greater than the US average (15).
Emergencies Declared: 10
Causes of natural disasters: Floods: 19, Storms: 13, Snows: 7, Winter Storms: 6, Heavy Rains: 3, Hurricanes: 3, Winds: 3, Blizzard: 1, Ice Storm: 1, Mudslide: 1, Snowfall: 1, Snowstorm: 1, Tornado: 1, Other: 2 (Note: some incidents may be assigned to more than one category).
Means of transportation to work:
Drove a car alone: 146,313 (77.9%)
Carpooled: 17,327 (9.2%)
Bus: 1,026 (0.5%)
Subway or elevated rail: 54 (0.0%)
Ferryboat: 161 (0.1%)
Taxicab, motorcycle, or other means: 1,971 (1.1%)
Bicycle: 1,074 (0.6%)
Walked: 8,033 (4.3%)
Worked at home: 11,747 (6.3%)
Most common industries in 2019 (%)
Males Females
Health care and social assistance (25%)
Educational services (13%)
Retail trade (11%)
Professional, scientific, and technical services (8%)
Finance and insurance (7%)
Accommodation and food services (6%)
Other services, except public administration (4%)
Most common occupations in 2019 (%)
Management occupations (16%)
Sales and related occupations (11%)
Construction and extraction occupations (7%)
Office and administrative support occupations (7%)
Business and financial operations occupations (6%)
Architecture and engineering occupations (5%)
Production occupations (5%)
Office and administrative support occupations (14%)
Educational instruction, and library occupations (9%)
Health diagnosing and treating practitioners and other technical occupations (9%)
Food preparation and serving related occupations (6%)
Other Eastern Africa (12%)
Canada (7%)
Democratic Republic of Congo (Zaire) (6%)
Vietnam (5%)
India (5%)
Somalia (4%)
Iraq (4%)
English (13%)
Irish (12%)
American (9%)
French Canadian (6%)
French (except Basque) (6%)
Italian (5%)
German (4%)
People in group quarters in Cumberland County, Maine in 2000:
3,454 people in college dormitories (includes college quarters off campus)
1,686 people in nursing homes
1,055 people in other noninstitutional group quarters
537 people in state prisons
374 people in military barracks, etc.
344 people in local jails and other confinement facilities (including police lockups)
317 people in homes for the mentally retarded
179 people in training schools for juvenile delinquents
123 people in religious group quarters
113 people in other group homes
113 people in other nonhousehold living situations
110 people in homes or halfway houses for drug/alcohol abuse
62 people in homes for the physically handicapped
59 people in homes for the mentally ill
44 people in halfway houses
26 people in homes for abused, dependent, and neglected children
13 people in wards in general hospitals for patients who have no usual home elsewhere
9 people in military ships
6 people in hospitals/wards and hospices for chronically ill
6 people in hospices or homes for chronically ill
2 people in mental (psychiatric) hospitals or wards
4,600 people in college/university student housing
1,748 people in nursing facilities/skilled-nursing facilities
530 people in other noninstitutional facilities
403 people in local jails and other municipal confinement facilities
356 people in group homes intended for adults
310 people in emergency and transitional shelters (with sleeping facilities) for people experiencing homelessness
205 people in residential treatment centers for adults
116 people in correctional facilities intended for juveniles
93 people in workers' group living quarters and job corps centers
54 people in group homes for juveniles (non-correctional)
39 people in military barracks and dormitories (nondisciplinary)
28 people in residential treatment centers for juveniles (non-correctional)
25 people in correctional residential facilities
12 people in in-patient hospice facilities
Average gross adjusted income of non-migrant taxpayers in this county in 2010 was $80,965.
Maine average:
2.81% relocated from other counties in Maine ($22,699 average AGI)
3.67% relocated from other states ($41,323 average AGI)
from York County, ME 0.99% ($51,464 average AGI)
from Androscoggin County, ME 0.39% ($52,487)
from Sagadahoc County, ME 0.31% ($60,456)
from Penobscot County, ME 0.23% ($78,156)
from Middlesex County, MA 0.23% ($87,315)
from Kennebec County, ME 0.21% ($47,178)
from Oxford County, ME 0.18% ($36,518)
0.05% of residents moved to foreign countries ($500 average AGI)
2.96% relocated to other counties in Maine ($20,872 average AGI)
3.24% relocated to other states ($35,697 average AGI)
to York County, ME 1.15% ($44,353 average AGI)
to Androscoggin County, ME 0.54% ($42,263)
to Sagadahoc County, ME 0.35% ($48,018)
to Kennebec County, ME 0.21% ($42,981)
to Oxford County, ME 0.20% ($36,805)
to Middlesex County, MA 0.14% ($52,389)
to Penobscot County, ME 0.13% ($41,994)
Births per 1000 population from 1990 to 1999: 12.6
Births per 1000 population from 2007 to 2019: 9.8
Deaths per 1000 population from 1990 to 1999: 8.8
Infant deaths per 1000 live births from 1990 to 1999: 5.3
Population without health insurance coverage in 2018: 8.4%
Persons under 19 years old without health insurance coverage in 2018: 4.7%
Percentage of population without health insurance coverage in Cumberland County
All 18-64 40-64 50-64 Under 19
Persons enrolled in hospital insurance and/or supplemental medical insurance (Medicare) in July 1, 2007: 44,779 (36,558 aged, 8,221 disabled)
Children under 18 without health insurance coverage in 2007: 2,406 (4%)
Most common underlying causes of death in Cumberland County, Maine in 1999 - 2019:
Bronchus or lung, unspecified - Malignant neoplasms (3,460)
Unspecified dementia (3,214)
Atherosclerotic heart disease (2,869)
Alzheimer disease, unspecified (2,374)
Chronic obstructive pulmonary disease, unspecified (2,328)
Acute myocardial infarction, unspecified (1,824)
Stroke, not specified as haemorrhage or infarction (1,528)
Congestive heart failure (1,279)
Pneumonia, unspecified (1,073)
Colon, unspecified - Malignant neoplasms (882)
Population without health insurance coverage in 2000: 6%
Children under 18 without health insurance coverage in 2000: 3%
Short term general hospitals per 100,000 population in 2004: 1.83
Short term general hospital admissions per 100,000 population in 2004: 16,520
Short term general hospital beds per 100,000 population in 2004: 320
Emergency room visits per 100,000 population in 2004: 56,663
General practice office based MDs per 100,000 population in 2005: 1,066
Medical specialist MDs per 100,000 population in 2005: 865
Dentists per 100,000 population in 1998: 5
Total births per 100,000 population, July 2005 - July 2006 : 68
Total deaths per 100,000 population, July 2005 - July 2006: 124
Limited-service eating places per 100,000 population in 2005 : 16
Beer, wine & liquor stores per 100,000 population in 2005: 1
Homicides per 1,000,000 population from 2000 to 2006: 14.2. This is less than state average.
Suicides per 1,000,000 population from 2000 to 2006: 106.4. This is less than state average.
Deaths per 1,000,000 population:
Firearm - 49.5
Suffocation - 25.3
Poisoning - 22.1
Other - 9.5
Households: 295,003
Male householders: 60,437 (16,515 living alone), Female householders: 64,488 (23,343 living alone)
58,922 spouses (57,413 opposite-sex spouses), 9,370 unmarried partners, (8,302 opposite-sex unmarried partners), 70,179 children (66,068 natural, 2,247 adopted, 1,864 stepchildren), 2,990 grandchildren, 967 brothers or sisters, 2,470 parents, 707 foster children, 2,605 other relatives, 12,984 non-relatives
In group quarters: 8,884
Size of family households: 36,457 2-persons, 14,527 3-persons, 13,948 4-persons, 4,441 5-persons, 1,436 6-persons, 931 7-or-more-persons.
Size of nonfamily households: 39,858 1-person, 11,019 2-persons, 1,930 3-persons, 378 4-persons.
39,837 married couples with children.
10,218 single-parent households (3,128 men, 7,090 women).
92.4% of residents of Cumberland speak English at home.
1.2% of residents speak Spanish at home (79% speak English very well, 11% speak English well, 7% speak English not well, 3% don't speak English at all).
3.2% of residents speak other Indo-European language at home (75% speak English very well, 17% speak English well, 7% speak English not well, 1% don't speak English at all).
1.3% of residents speak Asian or Pacific Island language at home (59% speak English very well, 21% speak English well, 18% speak English not well, 3% don't speak English at all).
1.7% of residents speak other language at home (49% speak English very well, 34% speak English well, 15% speak English not well, 2% don't speak English at all).
In fiscal year 2004:
Federal Government expenditure: $1,821,204,000 ($6,659 per capita)
Department of Defense expenditure: $318,198,000
Federal direct payments to individuals for retirement and disability: $661,932,000
Federal other direct payments to individuals: $283,686,000
Federal direct payments not to individuals: $4,891,000
Federal grants: $403,715,000
Federal procurement contracts: $178,100,000 ($136,993,000 Department of Defense)
Federal salaries and wages: $288,880,000 ($138,283,000 Department of Defense)
Federal Government direct loans: $7,874,000
Federal guaranteed/insured loans: $216,657,000
Federal Government insurance: $159,125,000
Population change from April 1, 2000 to July 1, 2005:
Births: 15,630
57 per 1000 residents
Deaths: 12,420
Net international migration: +2,080
+8 per 1000 residents
Net internal migration: +4,416
+16 per 1000 residents
Total withdrawal of fresh water for public supply: 28.15 millions of gallons per day (18% from ground, 82% from surface)
Year house built in Cumberland County, Maine
15,7732000 to 2009
38,2271939 or earlier
Rooms in houses/apartments in Cumberland County, Maine
Rooms in owner-occupied houses in Cumberland County, Maine
1,6433 rooms
14,5795 rooms
14,2169+ rooms
Rooms in renter-occupied apartments in Cumberland County, Maine
1,8691 room
1,1369+ rooms
Bedrooms in houses/apartments in Cumberland County, Maine
Bedrooms in owner-occupied houses in Cumberland County, Maine
19,0462 bedrooms
4,6335+ bedrooms
Bedrooms in renter-occupied apartments in Cumberland County, Maine
2,298no bedroom
12,5041 bedroom
Cars and other vehicles available in Cumberland County, Maine in houses/condos/apartments
Cars and other vehicles available in Cumberland County in owner-occupied houses/condos
1,591no vehicle
23,7041 vehicle
43,5672 vehicles
4,3404 vehicles
1,8925+ vehicles
Cars and other vehicles available in Cumberland County in renter-occupied apartments
6855+ vehicles
86.1% of Cumberland County residents lived in the same house 1 years ago.
Out of people who lived in different counties, 44% lived in Maine.
State average:
This state: 159,806
Other state: 112,940
Northeast: 73,279
Midwest: 12,795
South: 17,923
West: 8,943
Most commonly used house heating fuel in Cumberland County
59.8%Fuel oil, kerosene, etc.
1.1%Other fuel
0.2%Coal or coke
Students in private schools in grades 1 to 8 (elementary and middle school): 1,977
Students in private schools in grades 9 to 12 (high school): 2,054
Students in private undergraduate colleges: 5,129
Expenditure Revenue Debt Cash and Securities
Cumberland County government finances - Expenditure in 2018:
Bond Funds - Cash and Securities: $1,187,000
Charges - Other: $7,545,000
Parking Facilities: $581,000
Miscellaneous Commercial Activities: $36,000
Construction - Correctional Institutions: $733,000
Judicial and Legal Services: $674,000
Current Operations - Correctional Institutions: $18,561,000
Police Protection: $8,196,000
Judicial and Legal Services: $2,375,000
General Public Buildings: $2,301,000
Central Staff Services: $2,123,000
General - Other: $1,540,000
Housing and Community Development: $1,230,000
Financial Administration: $936,000
Public Welfare - Other: $826,000
Natural Resources - Other: $187,000
Health - Other: $158,000
Parking Facilities: $88,000
Libraries: $10,000
Federal Intergovernmental - Other: $3,109,000
General - Interest on Debt: $822,000
Intergovernmental to Local - Other - Housing and Community Development: $1,043,000
Local Intergovernmental - Other: $3,538,000
Long Term Debt - Beginning Outstanding - Unspecified Public Purpose: $37,903,000
Outstanding Unspecified Public Purpose: $36,040,000
Retired Unspecified Public Purpose: $1,863,000
Miscellaneous - General Revenue - Other: $198,000
Sale of Property: $13,000
Interest Earnings: $8,000
Other Funds - Cash and Securities: $8,085,000
State Intergovernmental - Other: $4,381,000
Tax - Property: $29,283,000
Cumberland County government finances - Revenue in 2018:
Cumberland County government finances - Debt in 2018:
Cumberland County government finances - Cash and Securities in 2018:
Supplemental Security Income (SSI) in 2006:
Total number of recipients: 4,899
Number of aged recipients: 410
Number of blind and disabled recipients: 4,489
Number of recipients under 18: 480
Number of recipients between 18 and 64: 3,577
Number of recipients older than 64: 842
Number of recipients also receiving OASDI: 2,038
Amount of payments (thousands of dollars): 2,115
(Based on 61 full tracts)
G) Loans On Manufactured
Home Dwelling (A B C & D)
LOANS ORIGINATED 1,112 $195,754 1,900 $214,241 9,060 $205,453 885 $91,684 30 $700,600 1,181 $223,494 100 $70,030
APPLICATIONS APPROVED, NOT ACCEPTED 47 $184,447 235 $236,204 914 $212,608 93 $121,312 10 $704,200 115 $221,852 16 $56,250
APPLICATIONS DENIED 185 $194,270 353 $210,484 2,583 $221,834 293 $85,990 4 $4,175,000 367 $229,471 69 $59,797
APPLICATIONS WITHDRAWN 105 $185,905 179 $207,838 1,400 $209,174 63 $129,254 9 $534,444 136 $223,566 11 $93,364
FILES CLOSED FOR INCOMPLETENESS 16 $174,000 34 $259,588 311 $206,653 9 $138,222 0 $0 34 $232,765 7 $65,429
LOANS ORIGINATED 601 $197,865 2,368 $212,870 4,482 $199,363 1,207 $72,556 59 $461,576 1,060 $224,442 148 $61,973
APPLICATIONS APPROVED, NOT ACCEPTED 45 $187,978 393 $231,850 803 $206,009 139 $106,935 5 $795,400 171 $225,316 26 $79,577
APPLICATIONS DENIED 115 $202,000 486 $187,926 2,125 $206,757 452 $65,327 16 $474,063 302 $197,026 113 $60,513
APPLICATIONS WITHDRAWN 63 $181,556 237 $234,477 922 $210,517 93 $161,796 5 $5,325,600 110 $234,673 23 $75,870
FILES CLOSED FOR INCOMPLETENESS 12 $186,667 54 $208,463 179 $216,961 16 $154,688 1 $26,000 28 $214,786 3 $55,667
APPLICATIONS APPROVED, NOT ACCEPTED 13 $183,846 538 $213,212 857 $187,296 168 $66,179 8 $284,625 164 $230,250 36 $89,611
APPLICATIONS DENIED 35 $182,657 739 $192,859 2,713 $203,051 610 $68,770 11 $484,636 342 $217,772 172 $74,122
APPLICATIONS WITHDRAWN 18 $206,500 261 $188,751 1,158 $186,405 141 $84,908 7 $358,571 116 $196,414 11 $67,455
FILES CLOSED FOR INCOMPLETENESS 1 $209,000 86 $186,512 384 $217,534 34 $179,559 1 $500,000 36 $239,194 4 $132,750
APPLICATIONS WITHDRAWN 11 $170,364 416 $198,880 2,013 $176,178 156 $108,718 7 $702,286 132 $220,364 21 $92,952
FILES CLOSED FOR INCOMPLETENESS 1 $69,000 81 $170,049 466 $192,212 27 $63,519 2 $340,500 24 $249,375 7 $128,429
APPLICATIONS APPROVED, NOT ACCEPTED 4 $226,250 561 $191,365 935 $173,337 202 $82,629 2 $392,500 158 $207,259 43 $65,721
APPLICATIONS WITHDRAWN 13 $166,077 638 $172,975 2,894 $171,488 251 $141,080 18 $439,500 229 $206,965 38 $97,553
FILES CLOSED FOR INCOMPLETENESS 0 $0 132 $165,538 411 $191,572 47 $69,149 1 $290,000 38 $191,474 3 $139,000
APPLICATIONS APPROVED, NOT ACCEPTED 16 $177,563 454 $196,471 1,053 $155,963 193 $62,554 4 $520,750 152 $184,164 36 $63,333
APPLICATIONS WITHDRAWN 23 $183,478 476 $185,903 2,754 $154,262 231 $84,545 21 $952,333 173 $183,665 35 $92,229
FILES CLOSED FOR INCOMPLETENESS 10 $154,000 103 $202,524 397 $167,431 54 $90,944 0 $0 30 $236,167 4 $105,250
LOANS ORIGINATED 207 $159,159 3,582 $183,564 17,763 $147,838 1,090 $46,256 90 $435,078 1,648 $165,688
APPLICATIONS APPROVED, NOT ACCEPTED 10 $194,700 351 $184,698 1,708 $146,006 101 $39,366 3 $181,667 168 $186,667
APPLICATIONS DENIED 29 $149,379 389 $167,491 2,502 $148,582 285 $34,888 10 $426,900 230 $149,457
APPLICATIONS WITHDRAWN 20 $151,500 351 $172,843 2,349 $146,408 61 $39,557 3 $737,333 153 $176,124
FILES CLOSED FOR INCOMPLETENESS 1 $138,000 52 $183,615 360 $165,783 19 $41,737 1 $269,000 29 $176,207
APPLICATIONS WITHDRAWN 24 $135,625 232 $180,353 1,668 $137,932 67 $34,791 12 $346,250 99 $159,384
FILES CLOSED FOR INCOMPLETENESS 1 $157,000 35 $167,886 247 $142,498 7 $22,143 0 $0 15 $222,933
LOANS ORIGINATED 582 $124,919 3,730 $148,944 8,620 $134,807 694 $35,210 70 $327,900 899 $136,217
APPLICATIONS APPROVED, NOT ACCEPTED 28 $128,143 345 $142,316 780 $116,421 169 $34,130 2 $159,000 102 $126,176
APPLICATIONS DENIED 35 $128,800 470 $96,336 1,682 $108,521 316 $22,858 8 $210,375 115 $149,435
APPLICATIONS WITHDRAWN 28 $133,571 224 $152,683 1,447 $116,447 90 $32,089 9 $374,667 73 $141,288
FILES CLOSED FOR INCOMPLETENESS 5 $122,600 28 $134,536 291 $117,320 16 $35,375 0 $0 22 $145,591
APPLICATIONS APPROVED, NOT ACCEPTED 29 $126,690 314 $127,939 394 $95,581 215 $25,874 2 $86,500 32 $157,063
APPLICATIONS DENIED 44 $109,409 691 $78,608 1,232 $78,597 385 $24,745 8 $585,750 98 $95,602
APPLICATIONS WITHDRAWN 36 $119,167 254 $141,209 834 $86,821 69 $31,551 11 $441,091 42 $138,333
FILES CLOSED FOR INCOMPLETENESS 8 $112,625 39 $155,718 122 $103,344 11 $35,455 1 $165,000 7 $121,571
LOANS ORIGINATED 1,047 $107,228 3,453 $123,221 3,853 $104,427 802 $22,879 64 $397,734 628 $107,826
APPLICATIONS APPROVED, NOT ACCEPTED 29 $101,966 290 $113,990 662 $94,290 173 $30,838 3 $478,333 79 $125,684
APPLICATIONS DENIED 67 $106,179 503 $77,686 1,190 $80,877 363 $27,587 10 $187,100 138 $89,384
APPLICATIONS WITHDRAWN 50 $107,280 260 $129,735 1,049 $91,666 39 $31,128 9 $270,889 65 $117,815
FILES CLOSED FOR INCOMPLETENESS 10 $95,000 26 $165,731 161 $99,702 3 $22,333 0 $0 10 $174,400
LOANS ORIGINATED 213 $238,047 230 $240,739 9 $206,222
APPLICATIONS APPROVED, NOT ACCEPTED 89 $233,472 83 $232,072 8 $232,625
APPLICATIONS DENIED 37 $232,838 67 $244,104 3 $217,333
APPLICATIONS WITHDRAWN 18 $273,778 29 $234,379 0 $0
FILES CLOSED FOR INCOMPLETENESS 6 $186,000 2 $186,500 2 $199,000
D) Loans On Manufactured
Home Dwelling (A & B)
LOANS ORIGINATED 589 $212,988 324 $236,404 78 $215,744 1 $127,000
APPLICATIONS APPROVED, NOT ACCEPTED 168 $228,679 150 $230,453 20 $232,050 1 $82,000
APPLICATIONS DENIED 61 $201,180 36 $261,611 23 $194,739 1 $76,000
APPLICATIONS WITHDRAWN 35 $224,657 23 $246,522 5 $190,400 1 $138,000
FILES CLOSED FOR INCOMPLETENESS 14 $198,714 8 $213,750 5 $214,200 0 $0
APPLICATIONS APPROVED, NOT ACCEPTED 103 $229,398 104 $237,375 14 $244,643 0 $0
APPLICATIONS DENIED 16 $240,563 10 $245,000 3 $198,000 0 $0
FILES CLOSED FOR INCOMPLETENESS 0 $0 1 $255,000 0 $0 0 $0
APPLICATIONS APPROVED, NOT ACCEPTED 129 $221,775 70 $218,529 20 $209,200 0 $0
APPLICATIONS DENIED 11 $179,636 3 $235,667 1 $172,000 0 $0
APPLICATIONS WITHDRAWN 20 $238,900 17 $201,765 0 $0 2 $111,500
FILES CLOSED FOR INCOMPLETENESS 4 $200,500 3 $227,667 0 $0 0 $0
APPLICATIONS DENIED 21 $220,905 8 $199,875 10 $230,000 0 $0
APPLICATIONS WITHDRAWN 39 $224,513 17 $185,882 9 $204,667 0 $0
FILES CLOSED FOR INCOMPLETENESS 8 $296,125 1 $555,000 3 $303,000 0 $0
LOANS ORIGINATED 942 $196,856 307 $192,215 138 $203,493 5 $115,200
APPLICATIONS DENIED 26 $239,462 16 $257,313 7 $245,143 3 $114,667
APPLICATIONS WITHDRAWN 62 $194,516 49 $185,857 13 $215,923 0 $0
LOANS ORIGINATED 981 $178,478 663 $161,457 121 $175,603
APPLICATIONS APPROVED, NOT ACCEPTED 133 $180,722 147 $163,361 23 $207,304
APPLICATIONS WITHDRAWN 47 $186,213 66 $155,682 12 $169,083
FILES CLOSED FOR INCOMPLETENESS 1 $81,000 3 $155,667 1 $81,000
LOANS ORIGINATED 1,013 $162,162 486 $156,774 108 $162,259
APPLICATIONS WITHDRAWN 43 $157,442 43 $154,651 7 $170,286
LOANS ORIGINATED 1,020 $147,930 557 $145,278 89 $139,843
APPLICATIONS APPROVED, NOT ACCEPTED 141 $151,887 94 $143,138 18 $148,722
APPLICATIONS DENIED 30 $127,000 14 $148,429 15 $117,267
FILES CLOSED FOR INCOMPLETENESS 5 $141,400 3 $108,000 0 $0
LOANS ORIGINATED 986 $132,101 143 $132,993 82 $124,756
APPLICATIONS APPROVED, NOT ACCEPTED 97 $139,196 35 $145,886 10 $153,000
APPLICATIONS DENIED 43 $127,535 9 $173,667 7 $136,286
APPLICATIONS WITHDRAWN 26 $148,308 9 $153,667 1 $99,000
APPLICATIONS DENIED 51 $112,922 8 $132,125 19 $84,842
Most common first names in Cumberland County, ME among deceased individuals
Mary 1,862 80.8 years
John 1,757 74.8 years
William 1,356 74.8 years
Robert 1,288 71.7 years
George 1,050 76.5 years
Charles 1,027 75.9 years
Helen 941 82.0 years
James 933 73.1 years
Joseph 892 75.0 years
Dorothy 875 79.9 years
Most common last names in Cumberland County, ME among deceased individuals
Smith 646 77.2 years
Brown 544 77.2 years
Johnson 419 78.2 years
Davis 418 77.0 years
Libby 335 76.8 years
Thompson 272 78.8 years
Allen 262 77.0 years
Anderson 258 77.0 years
Clark 254 77.2 years
Jordan 238 78.4 years
Businesses in Cumberland County, ME
7-Eleven 7 J.Crew 1
ALDO 1 JCPenney 1
AT&T 9 JoS. A. Bank 1
Abercrombie & Fitch 1 Johnny Rockets 2
Ace Hardware 7 Journeys 1
Advance Auto Parts 4 Justice 1
Aeropostale 1 KFC 5
American Eagle Outfitters 1 Kincaid 2
Ann Taylor 1 Knights Inn 2
Apple Store 1 Kohl's 1
Applebee's 4 La Quinta 1
Arby's 2 La-Z-Boy 2
Ascend Collection 1 Lane Bryant 1
Ashley Furniture 3 Lane Furniture 4
Audi 1 LensCrafters 1
AutoZone 1 Little Caesars Pizza 3
BMW 1 Lowe's 4
Banana Republic 2 Macy's 1
Bath & Body Works 2 Marriott 5
Bed Bath & Beyond 1 Marshalls 2
Ben & Jerry's 1 MasterBrand Cabinets 49
Best Western 2 Mazda 2
Blockbuster 4 McDonald's 13
Brooks Brothers 1 Men's Wearhouse 1
Brookstone 1 Motel 6 1
Budget Car Rental 1 Motherhood Maternity 2
Buffalo Wild Wings 1 New Balance 7
Burger King 6 Nike 8
CVS 11 Nissan 1
Cache 1 Old Navy 2
Casual Male XL 1 Olive Garden 1
Catherines 1 On The Border 1
Chevrolet 4 Outback 1
Chico's 1 Outback Steakhouse 1
Chipotle 1 Pac Sun 2
Circle K 12 Panda Express 1
Clarion 1 Panera Bread 2
Clarks 1 Papa John's Pizza 3
Coldwater Creek 2 Penske 2
Comfort Suites 1 Pottery Barn 1
Cracker Barrel 1 Quiznos 2
Curves 4 RadioShack 8
Dairy Queen 4 Rite Aid 14
Days Inn 2 Rodeway Inn 1
Deb 1 Ruby Tuesday 2
Decora Cabinetry 7 Ryder Rental & Truck Leasing 1
Dennys 2 Sam's Club 1
Domino's Pizza 5 Sears 6
DressBarn 1 Sephora 1
Dressbarn 1 Shaw's 9
Dunkin Donuts 38 Spencer Gifts 1
Econo Lodge 2 Sprint Nextel 1
Eddie Bauer 1 Staples 4
Express 1 Starbucks 12
Extended Stay America 1 Subaru 1
Famous Footwear 3 Subway 25
Fashion Bug 3 Super 8 2
FedEx 59 T-Mobile 13
Foot Locker 1 T.J.Maxx 2
Ford 4 Taco Bell 5
Forever 21 1 Talbots 3
GNC 15 Target 1
GameStop 4 Toyota 1
Gap 2 Toys"R"Us 3
Goodwill 5 Trader Joe's 1
Gymboree 2 Travelodge 1
H&M 1 True Value 7
H&R Block 12 U-Haul 11
Haworth 1 U.S. Cellular 10
Hilton 6 UPS 59
Holiday Inn 4 Urban Outfitters 1
Home Depot 3 Verizon Wireless 5
HomeTown Buffet 1 Victoria's Secret 1
Honda 1 Volkswagen 2
Hot Topic 1 Walgreens 4
Howard Johnson 2 Walmart 5
Hyundai 2 Wendy's 6
IHOP 1 Whole Foods Market 1
IZOD 1 World Gym 1
J. Jill 1 YMCA 2
Browse common businesses in Cumberland County, ME
Cumberland County on our top lists:
#28 on the list of "Top 101 counties with the highest percentage of residents that exercised in the past month"
#30 on the list of "Top 101 counties with the best general health status score of residents (1-5), 3 years of data"
#40 on the list of "Top 101 counties with the highest percentage of residents that visited a dentist within the past year"
#43 on the list of "Top 101 counties with the highest Nitrogen Dioxide air pollution readings in 2012 (ppm)"
#49 on the list of "Top 101 counties with the lowest number of births per 1000 residents 2007-2013 (pop 50,000+)"
#55 on the list of "Top 101 counties with the highest carbon monoxide air pollution readings in 2012 (ppm)"
#74 on the list of "Top 101 counties with the highest Sulfur Oxides Annual air pollution readings in 2012 (µg/m3)"
#81 on the list of "Top 101 counties with the lowest percentage of residents that keep firearms around their homes"


Coriander, cilantro, meh they're all the same, right? Same plant, yes, but different part and different effect. Cilantro is the leafy green part while coriander is the seed. So what's so special about coriander? Anti-oxidants. And more.
It's also very nice in Tracy Anderson's turkey spinach crumble.
Coriander may not be the most universal spice, nor the most powerful on the health properties, but it blends well with cumin, and can be nice to add flavor and an additional health boost to dishes.


4th of July is around the corner ! The day brings on the cheerful times of red, white and blue.
You can celebrate American Independence Day with barbecues, picnics, parades and fireworks and also send Happy Fourth of July Greeting Cards to all your friends, family and loved ones and wish them a Happy 4th of July with our greeting cards.
You can send these 4th of July Greetings to all via Email, Facebook, Twitter, WhatsApp, etc.
Note : Click on the Happy 4th of July 2018 Greeting Cards photo to send the greeting card to all for FREE.


We can also help you with a catering arrangement for your corporate meeting or seminar session. To help save you hassle and shipping costs, you can also rent audio and visual equipment here on site.
Contact your preferred location for inquiries about availability!


text:
Orto steht für:

 Orto (Korsika), eine französische Gemeinde im Département Corse-du-Sud
 Orto (Galicien), eine spanische Gemeinde in der Provinz Galicien
 ORTO (Verlag), ein 1944–1973 tätiger estnischer Exilverlag

Orto ist der Familienname folgender Personen:

 Marbriano de Orto († 1529), frankoflämischer Komponist und Sänger

Siehe auch:
 Ortho

redpajama_set_name: RedPajamaWikipedia


The Cass County Sheriff's Office has recovered the following lost or stolen property. If you believe the property belongs to you, or may know whom it does belong, please contact our Evidence Technician at (816) 380-8316, or click HERE to send an email.
All property listed will be destroyed after 6 months after the date of recovery.


text:
FDA Approves Subcutaneous Formulation of Actemra for Use in Active Systemic Juvenile Idiopathic Arthritis (SJIA), a Rare Form of Juvenile Arthritis
Category: Antibodies
Published on Friday, 14 September 2018 11:51
SOUTH SAN FRANCISCO, CA, USA I September 13, 2018 I Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today that the U.S. Food and Drug Administration (FDA) has approved the subcutaneous (SC) formulation of Actemra® (tocilizumab) for the treatment of active systemic juvenile idiopathic arthritis (SJIA) in patients two years of age and older. Actemra can be given alone or in combination with methotrexate (MTX) in patients with SJIA. In 2011, FDA approved the intravenous (IV) formulation of Actemra for patients two years of age and older with active SJIA.
"Systemic juvenile idiopathic arthritis is a rare, debilitating disease with limited treatment options," said Sandra Horning, M.D., chief medical officer and head of Global Product Development. "We are pleased to now offer physicians the flexibility to prescribe for children two years of age and older either Actemra IV, administered in a medical office, or Actemra subcutaneous, a prefilled syringe that can be injected at home."
SJIA is the rarest form of juvenile idiopathic arthritis (JIA), a chronic arthritic disease affecting children.1 JIA affects nearly 300,000 children in the U.S., of which SJIA accounts for around 10 percent. SJIA is characterized by inflammation in one or more joints, and a daily, spiking fever for at least two weeks, which may be accompanied by a skin rash.1 Other symptoms may include anemia, enlargement of the liver or spleen, and inflammation of the lining of the heart and/or lungs.1
The approval is based on data from the JIGSAW-118 study, a 52-week, open-label, multicenter, Phase 1b pharmacokinetic (PK)/pharmacodynamic (PD) bridging study designed to determine the appropriate dosing regimen of Actemra SC across a range of body weights (BWs) in children with SJIA.2 The study enrolled 51 patients aged one to 17 years with SJIA and inadequate response to NSAIDs and corticosteroids who were either Actemra naive or were receiving Actemra IV with adequate disease control. Actemra SC was administered open label according to a body weight –based dosing regimen: SJIA patients weighing <30 kg received 162 mg of Actemra every two weeks or 10 days; and SJIA patients weighing ≥30 kg received 162 mg of Actemra every week for 52 weeks. Model-computed PK and PD parameters, and safety were assessed.
In general, the safety observed for Actemra SC was consistent with the known safety profile of Actemra IV, with the exception of injection site reactions (ISRs). A higher frequency of Actemra SC treated patients experienced ISRs, 41 percent (21/51), compared to patients treated with Actemra SC for other approved indications. All ISRs reported were non-serious, and none required patient withdrawal from treatment or dose interruption.
The efficacy of Actemra SC in children two to 17 years of age is based on PK exposure and extrapolation of established efficacy of Actemra IV in SJIA patients and Actemra SC in patients with rheumatoid arthritis (RA).
About Actemra
Actemra was the first humanized interleukin-6 (IL-6) receptor antagonist approved for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have used one or more disease-modifying antirheumatic drugs (DMARDs), such as methotrexate (MTX), that did not provide enough relief. The extensive Actemra RA IV clinical development program included five Phase III clinical studies and enrolled more than 4,000 people with RA in 41 countries. The Actemra RA subcutaneous clinical development program included two Phase III clinical studies and enrolled more than 1,800 people with RA in 33 countries. Actemra subcutaneous injection is also approved for the treatment of adult patients with giant cell arteritis (GCA) and for patients two years of age and older with active polyarticular juvenile idiopathic arthritis (PJIA) or active systemic juvenile idiopathic arthritis (SJIA). In addition, Actemra is also used as the IV formulation for patients two years of age and older with active PJIA, SJIA or CAR T cell-induced cytokine release syndrome (CRS). Actemra is not approved for subcutaneous use in people with CRS. It is not known if Actemra is safe and effective in children with PJIA, SJIA or CRS under two years of age or in children with conditions other than PJIA, SJIA or CRS.
About Genentech
Founded more than 40 years ago, Genentech is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious and life-threatening medical conditions. The company, a member of the Roche Group, has headquarters in South San Francisco, California. For additional information about the company, please visit http://www.gene.com.
1 Arthritis Foundation. https://www.arthritis.org/about-arthritis/types/juvenile-idiopathic-arthritis-jia/what-is-juvenile-idiopathic-arthritis.php (Last accessed: July 19, 2018)
2 Brunner H et al. OP0103 Identification of optimal subcutaneous doses of tocilizumab in children with systemic juvenile idiopathic arthritis. Annals of the Rheumatic Diseases 2018;77:102.
SOURCE: Genentech