It has been some delightful and delicious months cooking the recipes of Ruth Reichl. A true GOURMET experience!
For IHCC's final theme, we could cook anything to celebrate the six months of cooking with her. Ah, Ruth, it seems like only yesterday….
I decided the perfect swan song for the Ruth odyssey would be a cookie, but not just any cookie would do. It had to be a delicious, homey cookie, one that reminded me of Ruth and her kitchen. I baked the very first recipe I came to in Gourmet Today, Mixed Dried Fruit Oatmeal Cookies.
In a large bowl cream the butter with the brown sugar and beat in the egg, the baking soda mixture, the flour, the salt, and the vanilla. Stir in the oats, the apricots, the prunes, and the cherries and combine the dough well. Drop rounded tablespoons of the dough about 4 inches apart onto greased baking sheets and with a fork dipped in cold water flatten and spread each mound into a thin round, about 2 1/2 inches in diameter. Bake the cookies in batches in the middle of a preheated 375°F. oven 8 to 10 minutes, or until they are golden, transfer them with a spatula to racks, and let them cool.
Cook's Note: The cookies keep in an airtight container at room temperature for 5 days.
Cookies for Ruth. Homey and comforting, just like her recipes and voice.
These are definitely my new favorite non-chocolate cookie. The vanilla just complements the dried fruit. You must try these, invite over a neighbor, brew a pot of tea, and enjoy these warm cookies.
Although I didn't post up every week (as I initially vowed), here's what Ruth and I cooked up for the IHCC odyssey.
. What's up next for I Heart Cooking Clubs? Check it out here.
What a gorgeous selection of recipes you made! I'm a fan of Ruth Reichl too, though I haven't made many of her recipes. I have the big fat Gourmet cookbook, and should follow your lead and try the recipes.
You do need to explore that big cookbook, Mae. I really would like to cook my way through it.
Some really super recipes here! And those oatmeal cookies look fantastic! Terrific recipe for that — thanks.
You have nailed the Ruth Odyssey: Homey and comforting, just like her recipes and voice. These oatmeal cookies look so amazing! This is a recipe to try.
Thanks, Shirley. Hope you do try it!
What a yummy collection of recipes! Those fruity oatmeal cookies look chewy and delicious.
What a fun month you've had and what a feast you've been cooking up. It all looks wonderful but the cookies seem very special. I good tribute to the month you've had.
Months and months! It's been a cool ride. I wish I could have posted every week.
What a delicious cooking experience you had with Ruth…she would be proud.
That makes me blush…that Ruth would be proud. I know that if I ever get the chance to meet her, I will be totally tongue-tied.
I love the idea of adding different dried fruits to an oatmeal cookie. Why stop with a raisin? In fact, I like dried cherries and cranberries way more than raisins. I'll have to give these a try.
Seriously, may be my favorite cookie recipe. The Diva is definitely my favorite sandwich! Thanks, Kim.


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Curriculum Overview from 4th August 2021
The Intercollegiate Surgical Curriculum Programme (ISCP) provides the approved UK framework for surgical training from completion of the foundation years through to consultant level. This area contains the most up-to-date version of the curriculum for each of the ten surgical specialties and core surgical training which are GMC-approved in the UK and approved by the RCSI in the Republic of Ireland.
The curriculum guides and supports training for UK certification, a UK Certificate of Eligibility for Specialist Registration via the Combined Programme (CESR-CP) or, in the Republic of Ireland, Certificate of Completion of Specialist Training (CCST) in a surgical specialty. The curriculum enables trainees to develop as generalists within their chosen surgical specialty, to be able to deliver an on-call emergency service and to deliver more specialised services to a defined level.
The curriculum was founded on the following key principles which support the achievement of these aims:
A common framework across all the specialties within surgery.
Curriculum standards that conform to the standards specified by the GMC/RCSI.
Delivery of the curriculum by surgeons who are appropriately qualified to deliver surgical training.
A robust assessment system to enable systematic progression through to completion of surgical specialty training.
Regulation of progression through training by the achievement of outcomes that are specified within the specialty curricula.
Formulation and delivery of surgical care by surgeons working in a multidisciplinary environment.
Collaboration with those charged with delivering health services and training at all levels.
Equality, diversity and inclusion are integral to the rationale of the curriculum, underpinned by the generic professional capabilities component and the Joint Surgical Colleges Equality and Diversity Policy (July 2013). The ISCP encourages a diverse surgical workforce to be realised through each individual hospital trust's equality and diversity management policies, using methods that will:
ensure that every individual is treated with dignity and respect irrespective of their age, disability, race, religion, sex, sexual orientation or marital status, or whether they have undergone gender reassignment or are pregnant.
promote equal opportunities and diversity in training and the development of a workplace environment in which colleagues, patients and their carers are treated fairly and are free from harassment and discrimination.
Transfer to the latest curriculum
Where an older version of the curriculum is superseded, trainees will be expected to transfer to the most recent version in the interests of patient safety and educational quality.
You should transfer to the August 2021 curriculum if you are:
entering Core Surgical Training (CT1) or Run-through training (ST1)
entering Cardiothoracic Surgery or Neurosurgery at CT2 or ST2
entering Specialty Training at ST3 (or ST2 Neurosurgery )
entering a new Specialty Training level from ST4 to ST6 (OMFS/Urology) or ST7
a CESR applicant
You will not need to transfer if you are:
entering the final year of Core Surgical Training (CT2) or Run-through training (ST2) (except as above)
entering your final year of Specialty Training ST7 (OMFS/Urology) or ST8
remaining at your current level, on less than full time or out of programme
However, if you wish to transfer, please speak to your Training Programme Director.
All trainees must have transitioned to the 2021 curriculum by 2nd August 2023.
How to transition to the new curriculum?
This video illustrates whether you need to transfer to the August 2021 Curriculum and how todo so.
Please see Transition arrangements for more information.

redpajama_set_name: RedPajamaCommonCrawl


mom165744 reviewed Have you tried using Coke for headlice?
I've never heard of that. Someone told be to add a couple of drops of tea tree oil to water and put it in a spray bottle. Spray it in your kids hair and is will help prevent lice. Apparently the lice don't like the smell of tea tree oil. I've been using it on my son for 3 years now.


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Archives, Library, Women
HISTORY DAY 2018
A chance for students and researchers to discover more about available research collections, History Day 2018 will feature a joint offering from IMechE, IET, IOM3 and The Aeronautical Society (The Engineering Institutions' Librarians' Committee). This year we are throwing a spotlight on our first female members and our membership holdings.
Book now for History Day!
Founded in 1866, The Aeronautical Society of Great Britain (later The Royal Aeronautical Society) admitted women on an equal footing from the start – although classified as Associate Members they enjoyed the same terms and rules as Members. The first women to take advantage of this joined in 1874, Ethel Bourne aka the novelist Evelyn Burne. She used the pseudonym for writing because "I wish to remain unknown until I can write a book I consider sufficiently good to have my own name" (Bourne to Rupert Simms, 1892). By 1909 women could apply as full members.
Membership lists and early membership forms. The details recorded on these early forms are rather sparse, Amy Johnson's merely records her address and qualifications. Other well-known female members include, Gertrude Bacon who popularised flying for women and also contributed to the fields of botany and astronomy. One of her many accolades is that she was the first woman in England to make a proper balloon ascent, in 1898.
Amy Johnson's membership form
Another reasonably early adopter of female members was the Institution of Automotive Engineers (IAE). Established in 1905, Cleone de Heveningham Benest wrote asking if women can enter as Graduates in 1907. It was decided against but "that interested ladies could receive reports of Proceedings in the meantime" (IAE minutes, 1905-1907). In 1914 IAE Member Lucien Alphonse Legros put the matter before Council, arguing that women should be admitted. In the same year Dorothée Aurélie Marianne Pullinger applied as an Associate as the bye-laws stated a "person" could apply. However, on advice from the Royal Society it was advised that a person meant a man – Legros and Pullinger were duly refused. Another request, on the basis that women's war work had altered things, was put forward internally in 1916 but it was again denied. Things changed in 1920, IAE accepted a request from Women's Engineering Society (WES) to accept women. The first two to join were Benest and Pullinger, they were admitted in the same session in 1920.
IAE merged with the Institution of Mechanical Engineers (IMechE) in 1947. Until c1934 IAE Minutes list Members names – membership files also survived but these are not complete, they are normally detailed. The Institution of Locomotive Engineers (ILochE) also merged with IMechE (1969) but no female members have been found, all that remains of their membership records are index cards of names and subscription rates.
Dorothée Pullinger's 2nd application to the Institution of Automobile Engineers
The IMechE was founded in 1847, the bye-laws explicitly excluded women. However, they changed their outlook in 1920 following the passage of the Sex Disqualification (Removal) Act. This specifically stated that sex or marital status could not be a bar to admission to any incorporated society and forbade Universities from regulating the admission of women. IMechE's lawyer advised that "he, him and his" now had to read "he or she" in the bye-laws etc. He added that all other qualifications required for membership remained unchanged – a female applicant for membership would have to meet the same technical and educational standards as male applicants. It was presumably with this advice in mind that IMechE Minutes contain a footnote stating that the decision in December 1920 not to elect Miss Verena Holmes as a member "was made strictly on the merits of the case, and without prejudice on account of the candidate's sex". Holmes was elected in 1924, becoming the IMechE's first female Member.
All of IMechE's membership applications have survived, except for a very few of the earliest. These early ones, for the first decade or so, only list names and nominators but later ones have full biographies. IMechE, IAE and ILochE membership data 1847-1938 are on Ancestry.
Verena Holmes
Both Pullinger and Holmes were active members of WES, whose records are now at The Institution of Engineering and Technology (IET). WES was formed in 1919 by women who wanted to resist the pressure to leave engineering at the end of the First World War, and to promote engineering as a suitable profession for women. By 1918 almost 1 million women were working in engineering and munitions. Although it was shown that trained women performed extremely well, the 1919 Restoration of Pre-War Practices Act forced women to give up their jobs to men returning from military service. WES was active throughout the inter-war years, and was instrumental in mobilizing large numbers of women to enter engineering during the Second World War. It was able to take steps to ensure that female engineers were not subject to the same post-war pressures in 1945. IET's first female Student, Graduate and Associate Member was Gertrude Entwisle (1916, 1919 and 1920). Their first female member was Hertha Ayrton, 1889.
The IET Archives holds records of its own women members, from Ayrton to the present day. They are also home to the archives of WES – their journal holds a lot of member information and is free online. Also of note, the papers of Dame Caroline Haslett (first women to be appointed to the British Electricity Authority) and the archive of the Electrical Association for Women (a consumer organisation founded in 1924 to encourage the use of electricity in the home).
Gertrude Entwisle
The Institute of Materials, Minerals and Mining (IOM3) was formed via a number of mergers that reach back to The Iron and Steel Institute, founded 1869. Their first female member can be found among these predecessor bodies, Georgina Elizabeth Kermode became a member of the Institute of Metals in 1916. She spent time living in Tasmania where she became deeply interested in the treatment of ores and foresaw the possibilities of electrolytic treatment. Kermode travelled to England to expand her knowledge, on her return to Tasmania she sought to develop the electrolytic zinc industry.
IOM3 have an index of members 1909-1921 and a members list for 1923 for the Institute of Metals (a predecessor body).
The National Aerospace Library
The Hub, Fowler Avenue
Farnborough Business Park
Hampshire, GU14 7JP
T: +44 (0)1252 701038 or +44 (0)1252 701060
E: nal@aerosociety.com
W: https://www.aerosociety.com/news-expertise/national-aerospace-library/
Institution of Mechanical Engineers, Archive
1 Birdcage Walk
London, SW1H 9JJ
E: archive@imeche.org
W: https://www.imeche.org/libraries-archive/archive-and-artefacts
Institution of Engineering and Technology
Archive Centre
Savoy Hill House, 7-10 Savoy Hill
London, WC2R 0BU
E: archives@theiet.org
W: https://www.theiet.org/resources/library/archives/index.cfm
Institute of Materials, Minerals & Mining, Archive
297 Euston Road
London, NW1 3AQ
E: online enquiry form
W: https://www.iom3.org/national-materials-and-mining-archive
imechearchive November 19, 2018 January 17, 2019 Archive, Automotive, IMechE members, Institution members, Library, membership, Women
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Henry Ward Beecher became minister of Plymouth Congregational Church in Brooklyn (shown here with his equally famous sister Harriet Beecher Stowe) in 1847. He spent time in Lenox 1853-1857. A progressive active in the anti-slavery movement, he became part of the early Lenox intelligentsia.
His stopovers included visiting the Lenox Sedgwicks and preaching at Church on the Hill. He and his family stayed at a house they called Blossom Farm.
It was located on what is now Route 20/ Lee Road in an area called, for awhile, Beecher Hill.
In a great example of historical connect the dot, this property was part of a 75 acre plot sold in 1770 to Timothy Way and Samuel Jerome. Samuel Jerome is alleged to be an ancestor of Jenny Jerome, Churchill's American mother who had come to Elizabeth Sedgwick's school at the Hive.
In 1803 the hill was sold to Ezra Blossom — the gaoler of Lenox (jailer/sheriff). Blossom built a farmhouse, planted fruit trees, and named the property Blossom Hill.
In 1850 the property was sold to Charles Hotchkiss, Headmaster of the Lenox Academy.
In his day, Beecher was called one of the most famous men alive, but his sister, Harriet Beecher Stowe author of Uncle Tom's Cabin, would eclipse him.
Beecher was named correspondent in a divorce case – not a proper role for a clergyman – and his fortunes began to unravel. Before the scandal, the $4,500 to purchase Blossom Farm was raised by a grateful congregation and a grateful publisher.
After the scandal, Beecher lost his New York pulpit and was forced to sell the Lenox property. Beecher sold it to General John F. Rathbone for the tidy sum of $8,000.
The old farmhouse was moved to accommodate the first Wyndhurst in 1857. Although quite opulent by mid-century standards it was destined to be replaced.
J.D. Sloane was the brother of W. D. Sloane (Elm Court). Together they established WJ Sloane & Co. in New York City.
Sloane's Wyndhurst met the new standard in Berkshire Cottages. It was a Tudor mansion built of Perth Amboy brick designed by Peabody and Stearns. The landscape architect was Frederick Law Olmsted.
There was a stable with 16 boxes, a poultry shelter, and cow barn. Milk and cream were shipped daily to the family in New York and produce was shipped three times a week. Everything necessary was on the estate to maintain the Gilded Age lifestyle including obligatory visit of President of the United States (McKinley) as a dinner guest in 1897.
Meanwhile, at the back of the hill, another family had built their own enormous cottage. U.S. Naval Captain, John S. Barnes, Flag Officer of the North Atlantic Fleet during the Civil War, purchased the land for $10,000 in 1882 and erected Coldbrook. The railroad entrepreneur kept expanding the Peabody and Stearns original shingle style Queen Anne.
Pinecroft is described as being adjacent to the Haggertys (Vent Fort) and later, across the street from Thistlewood. It is identified as one of the properties combined with Coldbrook and Wyndhurst to form a hunt then golf club. From that evidence, best guess is that it was roughly between the modern location of Schmerhorn Court and the Pinecroft development.
To picture the combined estates, you have to imagine a world without Route 20.
Unusual for Lenox at the time, it was brick and stood at least until 1890 since it is, as noted above, mentioned in the article sending up the construction of Thistlewood.
It was built for the recently widowed Adeline Schermerhorn. She is particularly remembered in Lenox for purchasing the second courthouse (now out of use with the court having moved to Pittsfield) in 1872 for use as the town library. One of her daughters, Ellen, married Richard Tylden Auchmuty. They would go on to build The Dormers and play a very active role in the construction of the new Trinity church.
The southeastern end of this cluster of "cottages" began its story with another adulterous clergyman. Another celebrity preacher, Rev. Russell Salmon Cook (1811-1864). In 1853 he purchased property in Lenox that included a ramshackle farm house. In a dust up over money and the Reverend's third (fourth?) marriage, he needed to abandon his property.
It was taken over by two New York brothers (one a bachelor, the other a widower), Francis and George Dorr. They expanded the house and planted the grounds – including large specimen trees. Their property made up about half of the several hundred acres acquired by Robert Paterson for what would become Blantyre.
Robert Paterson was introduced to the Lenox area in the late 1890's by his friend John Sloan (of W&J Sloane).
Paterson tore down the modest Dorr house, keeping the outbuildings and started building a property on a grand scale, He told his architect, Robert Henderson Robertson. that he wanted a castle of "feudal architectural features," replete with towers, turrets and gargoyles.
The house was modeled after his mother's ancestral home in Blantyre, Scotland. Construction began in 1901, at times employing over 300 people on the grounds and buildings.
The main house was furnished in the English style with all the furniture being brought in from England. The family used the house for the summer and fall and there were garden parties with musicians imported from New York and grand dinner-dances with each party becoming more and more lavish.
In the 1920's the property evolved with its neighbors Wyndhurst and Coldbrook. Blantyre deteriorated considerably in the 1970's. In the 1980's it was restored by the late Ann Fitzpatrick Brown and is now run as a luxury hotel.
By 1928, the party was over. The Gilded Age was ended, and the cottages were relics of a bygone era. On the hill, an ambitious plan for aBerkshire Hunt and Country Club combined four former estates – Wyndhurst, Coldbrook, Pinecroft, and Blantyre. Woodson R. Oglesby, former New York Congressman, started buying the estates at foreclosures.
On August 10, 1929 there was a full page spread about the second season of the Club. On an adjacent page it was reported that a Williams College professor warned, "Unemployment is a problem in need of an immediate solution." A column on the financial page predicted, "The Stock Market will rally after a minor dip." The Market crashed on Black Tuesday, October 29, 1929, two months and 19 days later.
The country was in depression. For a moment it looked as if those Club members would be untouched and the Club would continue. By 1933 the Club was assaulted by lawsuits and swamped in debt. In 1939, the land on the hill was sold for (approximately) $9,000 in back taxes.
For that price, Edward Cranwell bought the hill with two Berkshire Cottages: Wyndhurst and Coldbrook. In 1939, he gave it to the Jesuits to use as a school. The Jesuits named the school in honor of the donor — Cranwell Preparatory School.
The school closed in 1975. Coldbrook and Cranwell (Wyndhurst) are now operated as a condominium and resort complex, Pinecroft has been demolished, and Blantyre is a luxury hotel.


The fishmeal production process comprises three basic phases, namely indirect steam cooking, pressing of the cooked fish matter, and indirect drying. Evaporation units are used to concentrate the exuded cooked liquid (fish water); the concentrate is then added back to the fishmeal process before final drying. In summary, the process is a reduction of raw fish into fishmeal and fish oil, both of which are critical ingredients used in the specialised animal and aqua feed industry. At every stage, controls are in place to minimise unsavoury by-product and to ensure the quality of the ultimate product.
The South African stocks of sardine, anchovy, round herring, and horse mackerel are highly mobile migratory fish that occur in South African waters from the Orange River on the west coast to approximately Port Alfred on the east coast. Wooden and steel vessels use a purse seine net to catch the fish in the upper layers of the sea, and shoal sizes can reach 200 tons per catch. The raw material is stored in the hold of the vessels and transported as fast as possible to the fishmeal plant.
Raw material is pumped from the vessel to the storage pits where fish water is drained from the batch before weighing. The fish pits are completely enclosed and have refrigerated circulating cold air in order to maintain good quality and minimise autolytic deterioration.
The raw material is conveyed into the continuous steam jacketed cookers where the raw fish is cooked, causing the liberation of the fish solids, oil and water. The plant's cooker enables optimal temperature transfer and residence time for the fish.
While the plant employs various odour suppression technologies to target and minimise odour, the plant has a characteristic fishmeal-processing smell. This is especially noticeable during periods of overcast and low ambient temperate, during periods with wind direction towards residential areas and during periods of windless conditions.
The smell comes mainly from the driers, where hot air passes over the cooked fish matter and in the process emits odorous vapours that are entrained in the air stream. The indirect drying process used at the plant has no air in direct contact with the fishmeal and the vapour removed from the cooked fish can be condensed because of smaller volumes of air.
The fishmeal factory collects all production emissions from cookers, conveyors, driers and other processing equipment and channels it though a high-capacity seawater scrubber. This assists in condensing the odourous vapour and all non-condensables are then channelled to a balancing tank which divides the gases either in a two-phase chemical scrubbing system or into four boilers for gas combustion. An oxidising agent is used for chemical scrubbing in order to react and minimise the odourous compounds.
Other elements of the odour suppression system include enclosed and refrigerated fish holding tanks at fish intake phase as well as bag filters in the bagging phase.
While the plant employs all the above technology to target and minimise odour, it cannot completely eliminate the smell of fishmeal processing. The factory's intermittent operation schedules, which depend on fish availability as well as weather conditions during production, will produce the characteristic fish-processing odour. This may give a misleading impression of inefficiency at the plant and this website is part of our commitment to being open about the process.
The output from the cooker is then transported to a series of decanters which aid with the separation of the solids from the liquids.
The liquid is then pumped to centrifugal separators, producing stick water which is pumped into a holding tank for processing and oil which is polished and stored in tanks. The stick water contains fine solids which are concentrated in a Waste Heat Evaporator and this concentrate is then added to the solid phase in the driers.
Solids from the decanters are conveyed to indirect steam driers where concentrated process water is added to produce a mixture with a moisture content of 35%. Meal exiting the dryer is at a moisture content of less than 10%.
The bagging process has filters and cyclones that remove dust and recycle the fines back into the storage bags to reduce wastage. The final product is bagged into 50kg and/or bulk bags depending on customer demand.
Fishmeal – The final product is stored in warehouses pending despatch to customers.
Fish oil – The final product is loaded in bulk tankers and containers.
The plant uses four John Thompson Oil Fired Boilers with a steam capacity of 14000 kg/hr for two boilers, 16000 kg/hr for the remaining two.
The water vapour from the two indirect driers is passed through a waste heat evaporator to re-use the heat, the remaining vapour is condensed in scrubbers and the non-condensables are ducted to a mixing tank from which the boilers draw air to incinerate the odorous vapour. The air from the plant is also scrubbed and fed into the mixing tank. The surplus air not burnt in the boilers is treated in a chemical scrubber.
At the Hout Bay Fishmeal Factory, sewage water effluent is pumped into the municipal sewage system.
No water effluent is discharged into the sea. The fishmeal production does not produce any production effluent. However all wash water which is produced during cleaning is pumped to the City of Cape Town's sewage plant in Hout Bay. The factory samples the water effluent monthly and sends it to an independent laboratory for analysis. The plant utilises seawater in the scrubbers for cooling purposes and, if it does not come into contact with any plant liquids, is returned to the sea. This too is periodically sampled and then analysed by independent laboratories.
The Hout Bay Fishmeal Factory provides employment to 91 permanent shore-based staff and supports in excess of 120 seagoing employees.
Emissions from production processes at the Hout Bay Fishmeal Factory are associated with an unpleasant odour, the impact of which the plant is continuing to address and reduce.
Following a survey conducted in 1995-96, the CSIR produced a report on the impact of the factory – An Assessment of Community Exposure and Potential Health Effects of Emissions from the SA Sea Products in Hout Bay. The results of this survey confirmed that the processing of fishmeal and its associated activities do not constitute an environmental health risk.
A 2011 report of the St Helena Bay operations, based on independent studies and conducted on behalf of the Department of Environmental Affairs, also concluded that emissions at low levels pose no significant impact on human health. During recent and previous measurements of the exit gas from the odour abate system it was determined that the emission levels were within an acceptable range.
The plant operates under an environmental management plan (EMP), whereby fish volume restrictions are strictly enforced.
The Hout Bay Fishmeal Factory has undergone a thorough improvement process in the past two decades which has significantly reduced its odorous emissions.
Scientific analysis on raw material caught is performed daily and compiled into status reports. The data collected is used to monitor catches, abundance, distribution and biology and associated environmental information.


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UNITROPIN (somatropin rDNA origin for injection) – rHGH – Human Growth Hormone – 15 IU vial
UNITROPIN (somatropin [rDNA origin] for injection) is indicated for replacement of endogenous human growth hormone (hgh) in select patient populations with growth hormone deficiency, generally due to inadequate secretion of endogenoushuman growth hormone (hgh). In vitro, preclinical, and clinical tests have demonstrated that UNITROPIN lyophilized powder is therapeutically equivalent tohuman growth hormone of pituitary origin and achieves similar pharmacokinetic profiles in normal adults
UNITROPIN lyophilized powder contains somatropin [rDNA origin], which is a polypeptide hormone of recombinant DNA origin. It has 191 amino acid residues and a molecular weight of 22,124 daltons. The amino acid sequence of the product is identical to that of human growth hormone (HGH) of pituitary origin (somatropin). UNITROPIN is synthesized in a strain of Escherichia coli that has been modified by the addition of the gene for human growth hormone (rHGH).UNITROPIN is a sterile white lyophilized powder intended for subcutaneous injection.
UNITROPIN is a recombinant human growth hormone indicated for:
Pediatric: Treatment of children with growth failure due to growth hormone deficiency (GHD), Prader-Willi syndrome, Small for Gestational Age, Turner syndrome, and Idiopathic Short Stature.
Adult: Treatment of adults with either adult onset or childhood onset GHD
DOSAGE AND ADMINISTRATION (SUMMARY)
UNITROPIN should be administered subcutaneously:
Pediatric GHD: 0.16 to 0.24 mg/kg/week
Prader-Willi Syndrome: 0.24 mg/kg/week
Small for Gestational Age: Up to 0.48 mg/kg/week
Turner Syndrome: 0.33 mg/kg/week
Idiopathic Short Stature: up to 0.47 mg/kg/week
Adult GHD: Either a non-weight based or a weight based dosing regimen may be followed, with dose adjustment based on treatment response and serum IGF-I assay. (See Dosing of Adult Patients)
UNITROPIN lyophilized powder in a multi-dose vial. One vial of lyophilized powder product contains 5mg of Somatropin USP (15 IU approx.), Mannitol BP 45mg (buffer). Sodium Phosphate monobasic and dibasic 1.7mg (preservative), and Glycine 1.7mg.
After reconstitution, each UNITROPIN vial delivers 5mg (approx. 15 IU). Each package includes an ampule of bacteriostatic water as a solvent (2ml).
Acute Critical Illness: Potential benefit of treatment continuation should be weighed against the potential risk.
Prader-Willi syndrome in Children: Evaluate for signs of upper airway obstruction and sleep apnea before initiation of treatment. Discontinue treatment if these signs occur.
Neoplasm: Monitor patients with preexisting tumors for progression or recurrence. Increased risk of a second neoplasm in childhood cancer survivors treated with somatropin–in particular meningiomas in patients treated with radiation to the head for their first neoplasm
Impaired Glucose Tolerance and Diabetes Mellitus: May be unmasked. Periodically monitor glucose levels in all patients. Doses of concurrent antihyperglycemic drugs in diabetics may require adjustment.
Intracranial Hypertension: Exclude preexisting papilledema. May develop and is usually reversible after discontinuation or dose reduction.
Fluid Retention (i.e., edema, arthralgia, carpal tunnel syndrome –especially in adults): May occur frequently. Reduce dose as necessary.
Hypopituitarism: Closely monitor other hormone replacement therapies.
Hypothyroidism: May first become evident or worsen.
Slipped Capital Femoral Epiphysis: May develop. Evaluate children with the onset of a limp or hip/knee pain.
Progression of Preexisting Scoliosis: May develop.
ADULT PATIENTS
UNITROPIN is indicated for replacement of endogenous growth hormone in adults with growth hormone deficiency who meet either of the following two criteria:
Adult Onset (AO): Patients who have growth hormone deficiency, either alone or associated with multiple hormone deficiencies (hypopituitarism), as a result of pituitary disease, hypothalamic disease, surgery, radiation therapy, or trauma; or
Childhood Onset (CO): Patients who were growth hormone deficient during childhood as a result of congenital, genetic, acquired, or idiopathic causes.
Patients who were treated with somatropin for growth hormone deficiency in childhood and whose epiphyses are closed should be reevaluated before continuation of somatropin therapy at the reduced dose level recommended for growth hormone deficient adults.
The weekly dose should be divided into 6 or 7 subcutaneous injections. UNITROPIN must not be injected intravenously.
Dosing of Pediatric Patients
General Pediatric Dosing Information
UNITROPIN dosage and administration schedules should be individualized based on the growth response of each patient.
Response to somatropin therapy in pediatric patients tends to decrease with time.
Treatment with UNITROPIN for short stature should be discontinued when the epiphyses are fused.
Pediatric Growth Hormone Deficiency (GHD)
Generally, a dose of 0.16 to 0.24 mg/kg body weight/week is recommended.
Generally, a dose of 0.24 mg/kg body weight/week is recommended.
Turner Syndrome Generally, a dose of 0.33 mg/kg body weight/week is recommended.
Idiopathic Short Stature
Generally, a dose up to 0.47 mg/kg body weight/week is recommended.
Small for Gestational Age: Generally, a dose of up to 0.48 mg/kg body weight/week is recommended.
Dosing of Adult Patients
Adult Growth Hormone Deficiency (GHD)
Either of two approaches to UNITROPIN dosing may be followed: a non-weight based regimen or a weight based regimen.
Non-weight based– based on published consensus guidelines, a starting dose of approximately 0.2 mg/day (range, 0.15-0.30 mg/day) may be used without consideration of body weight. This dose can be increased gradually every 1-2 months by increments of approximately 0.1-0.2 mg/day, according to individual patient requirements based on the clinical response and serum insulin-like growth factor I (IGF-I) concentrations. The dose should be decreased as necessary on the basis of adverse events and/or serum IGF-I concentrations above the age- and gender-specific normal range.
Weight based–the recommended dosage at the start of treatment is not more than 0.04 mg/kg/week. The dose may be increased according to individual patient requirements to not more than 0.08 mg/kg/week at 4–8 week intervals. Clinical response, side effects, and determination of age- and gender-adjusted serum IGF-I concentrations should be used as guidance in dose titration.
A lower starting dose and smaller dose increments should be considered for older patients, who are more prone to the adverse effects of somatropin than younger individuals. In addition, obese individuals are more likely to manifest adverse effects when treated with a weight-based regimen. In order to reach the defined treatment goal, estrogen-replete women may need higher doses than men. Oral estrogen administration may increase the dose requirements in women.
Preparation and Administration
UNITROPIN is provided in 5 mg vials (approx. 15 IU).
Parenteral drug products should always be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. UNITROPIN MUST NOT BE INJECTED if the solution is cloudy or contains particulate matter. Use it only if it is clear and colorless.
UNITROPIN may be given in the thigh, buttocks, or abdomen; the site of SC injections should be rotated daily to help prevent lipoatrophy.
Acute Critical Illness
Treatment with pharmacologic amounts of somatropin is contraindicated in patients with acute critical illness due to complications following open heart surgery, abdominal surgery or multiple accidental trauma, or those with acute respiratory failure.
Prader-Willi Syndrome in Children
Somatropin is contraindicated in patients with Prader-Willi syndrome who are severely obese, have a history of upper airway obstruction or sleep apnea, or have severe respiratory impairment. There have been reports of sudden death when somatropin was used in such patients.
Active Malignancy
In general, somatropin is contraindicated in the presence of active malignancy. Any preexisting malignancy should be inactive and its treatment complete prior to instituting therapy with somatropin. Somatropin should be discontinued if there is evidence of recurrent activity. Somatropin should not be used in patients with any evidence of progression or recurrence of an underlying intracranial tumor.
Somatropin is contraindicated in patients with active proliferative or severe non-proliferative diabetic retinopathy.
Closed Epiphyses
Somatropin should not be used for growth promotion in pediatric patients with closed epiphyses.
UNITROPIN is contraindicated in patients with a known hypersensitivity to somatropin or any of its preservatives or other excipients. Localized reactions are the most common hypersensitivity reactions.
Increased mortality in patients with acute critical illness due to complications following open heart surgery, abdominal surgery or multiple accidental trauma, or those with acute respiratory failure has been reported after treatment with pharmacologic amounts of somatropin
Patients with preexisting tumors or growth hormone deficiency secondary to an intracranial lesion should be examined routinely for progression or recurrence of the underlying disease process. Patients should be monitored carefully for any malignant transformation of skin lesions.
Glucose Intolerance
Treatment with somatropin may decrease insulin sensitivity, particularly at higher doses in susceptible patients. As a result, previously undiagnosed impaired glucose tolerance and overt diabetes mellitus may be unmasked during somatropin treatment. Therefore, glucose levels should be monitored periodically in all patients treated with somatropin, especially in those with risk factors for diabetes mellitus, such as obesity, Turner syndrome, or a family history of diabetes mellitus. Patients with preexisting type 1 or type 2 diabetes mellitus or impaired glucose tolerance should be monitored closely during somatropin therapy. The doses of anti-hyperglycemic drugs (i.e., insulin or oral agents) may require adjustment when somatropin therapy is instituted in these patients.
Intracranial Hypertension
Intracranial hypertension (IH) with papilledema, visual changes, headache, nausea and/or vomiting has been reported in a small number of patients treated with somatropin products. Symptoms usually occurred within the first eight (8) weeks after the initiation of somatropin therapy. In all reported cases, IH-associated signs and symptoms rapidly resolved after cessation of therapy or a reduction of the somatropin dose.
Fluid retention during somatropin replacement therapy in adults may occur. Clinical manifestations of fluid retention are usually transient and dose dependent.
Patients with hypopituitarism (multiple pituitary hormone deficiencies) should have their other hormonal replacement treatments closely monitored during somatropin treatment.
Undiagnosed/untreated hypothyroidism may prevent an optimal response to somatropin, in particular, the growth response in children. Patients with Turner syndrome have an inherently increased risk of developing autoimmune thyroid disease and primary hypothyroidism. In patients with growth hormone deficiency, central (secondary) hypothyroidism may first become evident or worsen during somatropin treatment. Therefore, patients treated with somatropin should have periodic thyroid function tests and thyroid hormone replacement therapy should be initiated or appropriately adjusted when indicated.
Local and Systemic Reactions
As with any protein, local or systemic allergic reactions may occur. Patients should be informed that such reactions are possible and that prompt medical attention should be sought if allergic reactions occur.
Serum levels of inorganic phosphorus, alkaline phosphatase, parathyroid hormone (PTH) and IGF-I may increase during somatropin therapy.
Most Serious and/or Most Frequently Observed Adverse Reactions
This list presents the most serious and/or most frequently observed adverse reactions during somatropin treatment:
Sudden death in pediatric patients with Prader-Willi syndrome with risk factors including severe obesity, history of upper airway obstruction or sleep apnea and unidentified respiratory infection.
Intracranial tumors, in particular meningiomas, in young adults treated with radiation to the head as children for a first neoplasm and somatropin.
Glucose intolerance including impaired glucose tolerance/impaired fasting glucose as well as overt diabetes mellitus.
Intracranial hypertension.
Significant diabetic retinopathy.
Slipped capital femoral epiphysis in pediatric patients.
Progression of preexisting scoliosis in pediatric patients.
Fluid retention manifested by edema, arthralgia, myalgia, nerve compression syndromes including carpal tunnel syndrome/paraesthesias.
Unmasking of latent central hypothyroidism.
Injection site reactions/rashes and lipoatrophy (as well as rare generalized hypersensitivity reactions)
Clinical Trials in children with GHD
In clinical studies with UNITROPIN in pediatric GHD patients, the following events were reported infrequently: injection site reactions, including pain or burning associated with the injection, fibrosis, nodules, rash, inflammation, pigmentation, or bleeding; lipoatrophy; headache; hematuria; hypothyroidism; and mild hyperglycemia.
Clinical Trials in PWS
In two clinical studies with UNITROPIN in pediatric patients with Prader-Willi syndrome, the following drug-related events were reported: edema, aggressiveness, arthralgia, benign intracranial hypertension, hair loss, headache, and myalgia.
Clinical Trials in adults with GHD
In clinical trials with UNITROPIN in 1,145 GHD adults, the majority of the adverse events consisted of mild to moderate symptoms of fluid retention, including peripheral swelling, arthralgia, pain and stiffness of the extremities, peripheral edema, myalgia, paresthesia, and hypoesthesia. These events were reported early during therapy, and tended to be transient and/or responsive to dosage reduction.
Adverse events may include swelling, peripheral arthralgia, upper respiratory infection, pain in the extremities, peripheral edema, paresthesia, headache, stiffness of extremities, fatigue, myalgia, and back pain.
Anti-hGH Antibodies
As with all protein drugs, a small percentage of patients may develop antibodies to the protein. In a very small number of patients, when binding capacity was greater than 2 mg/L, interference with the growth response was observed.
Periplasmic Escherichia coli Peptides Preparations of UNITROPIN contain a small amount of periplasmic Escherichia coli peptides (PECP). Anti-PECP antibodies are found in a small number of patients treated with UNITROPIN, but these appear to be of no clinical significance.
Because these adverse events are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The following additional adverse reactions have been observed during the appropriate use of somatropin: headaches (children and adults), gynecomastia (children), and pancreatitis (children).
11 β-Hydroxysteroid Dehydrogenase Type 1 The microsomal enzyme 11β-hydroxysteroid dehydrogenase type 1 (11βHSD-1) is required for conversion of cortisone to its active metabolite, cortisol, in hepatic and adipose tissue. GH and somatropin inhibit 11βHSD-1. Consequently, individuals with untreated GH deficiency have relative increases in 11βHSD-1 and serum cortisol. Introduction of somatropin treatment may result in inhibition of 11βHSD-1 and reduced serum cortisol concentrations. As a consequence, previously undiagnosed central (secondary) hypoadrenalism may be unmasked and glucocorticoid replacement may be required in patients treated with somatropin. In addition, patients treated with glucocorticoid replacement for previously diagnosed hypoadrenalism may require an increase in their maintenance or stress doses following initiation of somatropin treatment; this may be especially true for patients treated with cortisone acetate and prednisone since conversion of these drugs to their biologically active metabolites is dependent on the activity of 11βHSD-1.
Pharmacologic Glucocorticoid Therapy and Supraphysiological Glucocortioid Treatment
Such treatments may attenuate the growth promoting effects of somatropin in children. Therefore, glucocorticoid replacement dosing should be carefully adjusted in children receiving concomitant somatropin and glucocorticoid treatments to avoid both hypoadrenalism and an inhibitory effect on growth.
Cytochrome P450-Metabolized Drugs
Limited published data indicate that somatropin treatment increases cytochrome P450 (CYP450)-mediated antipyrine clearance in man. These data suggest that somatropin administration may alter the clearance of compounds known to be metabolized by CYP450 liver enzymes (e.g., corticosteroids, sex steroids, anticonvulsants, cyclosporine). Careful monitoring is advisable when somatropin is administered in combination with other drugs known to be metabolized by CYP450 liver enzymes. However, formal drug interaction studies have not been conducted.
Oral Estrogen
In patients on oral estrogen replacement, a larger dose of somatropin may be required to achieve the defined treatment goal.
Insulin and/or Oral Hypoglycemic Agents
In patients with diabetes mellitus requiring drug therapy, the dose of insulin and/or oral agent may require adjustment when somatropin therapy is initiated.
Pregnancy Category B. Reproduction studies carried out with UNITROPIN at doses of 0.3, 1, and 3.3 mg/kg/day administered SC in the rat and 0.08, 0.3, and 1.3 mg/kg/day administered intramuscularly in the rabbit (highest doses approximately 24 times and 19 times the recommended human therapeutic levels, respectively, based on body surface area) resulted in decreased maternal body weight gains but were not teratogenic
There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed.
There have been no studies conducted with UNITROPIN in nursing mothers. It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when administering UNITROPIN to a nursing woman.
The safety and effectiveness of UNITROPIN in patients aged 65 and over have not been evaluated in clinical studies. Elderly patients may be more sensitive to the action of UNITROPIN, and therefore may be more prone to develop adverse reactions. A lower starting dose and smaller dose increments should be considered.
Short-term overdosage could lead initially to hypoglycemia and subsequently to hyperglycemia. Furthermore, overdose with somatropin is likely to cause fluid retention.
Long-term overdosage could result in signs and symptoms of gigantism and/or acromegaly consistent with the known effects of excess growth hormone.
In vitro, preclinical, and clinical tests have demonstrated that UNITROPIN lyophilized powder is therapeutically equivalent to human growth hormone of pituitary origin and achieves similar pharmacokinetic profiles in normal adults. In pediatric patients who have growth hormone deficiency (GHD), have Prader-Willi syndrome (PWS), were born small for gestational age (SGA), have Turner syndrome (TS), or have Idiopathic short stature (ISS), treatment with UNITROPIN stimulates linear growth. In patients with GHD or PWS, treatment with UNITROPIN also normalizes concentrations of IGF-I (Insulin-like Growth Factor-I/Somatomedin C). In adults with GHD, treatment with UNITROPIN results in reduced fat mass, increased lean body mass, metabolic alterations that include beneficial changes in lipid metabolism, and normalization of IGF-I concentrations.
Additionally, the following actions have been demonstrated for somatropin:
Tissue Growth
A. Skeletal Growth: UNITROPIN stimulates skeletal growth in pediatric patients with GHD, PWS, SGA, TS, or ISS. The measurable increase in body length after administration of UNITROPIN results from an effect on the epiphyseal plates of long bones. Concentrations of IGF-I, which may play a role in skeletal growth, are generally low in the serum of pediatric patients with GHD, PWS, or SGA, but tend to increase during treatment with UNITROPIN.
B. Cell Growth: It has been shown that there are fewer skeletal muscle cells in short-statured pediatric patients who lack endogenous growth hormone as compared with the normal pediatric population. Treatment with somatropin results in an increase in both the number and size of muscle cells.
Linear growth is facilitated in part by increased cellular protein synthesis. Nitrogen retention, as demonstrated by decreased urinary nitrogen excretion and serum
urea nitrogen, follows the initiation of somatropin therapy.
Pediatric patients with hypopituitarism sometimes experience fasting hypoglycemia that is improved by treatment with UNITROPIN. Large doses of growth
hormone may impair glucose tolerance.
In GHD patients, administration of somatropin has resulted in lipid mobilization, reduction in body fat stores, and increased plasma fatty acids.
Mineral Metabolism
Somatropin induces retention of sodium, potassium, and phosphorus. Serum concentrations of inorganic phosphate are increased in patients with GHD after therapy with UNITROPIN. Serum calcium is not significantly altered. Growth hormone could increase calciuria.
Adult GHD patients treated with UNITROPIN at the recommended adult dose demonstrate a decrease in fat mass and an increase in lean body mass. When these alterations are coupled with the increase in total body water, the overall effect of UNITROPIN is to modify body composition, an effect that is maintained with continued treatment.
Following a 0.03 mg/kg subcutaneous (SC) injection in the thigh of 1.3 mg/mL UNITROPIN to adult GHD patients, approximately 80% of the dose was systemically available as compared with that available following intravenous dosing. Results were comparable in both male and female patients. Similar bioavailability has been observed in healthy adult male subjects.
In healthy adult males, following an SC injection in the thigh of 0.03 mg/kg, the extent of absorption (AUC) of a concentration of 5.3 mg/mL UNITROPIN was 35% greater than that for 1.3 mg/mL UNITROPIN.
In a similar study involving pediatric GHD patients, 5.3 mg/mL UNITROPIN yielded a mean AUC that was 17% greater than that for 1.3 mg/mL UNITROPIN.
The mean volume of distribution of UNITROPIN following administration to GHD adults was estimated to be 1.3 (+/- 0.8) L/kg.
The metabolic rate of UNITROPIN involves classical protein catabolism in both the liver and kidneys. In renal cells, at least a portion of the breakdown products are returned to the systemic circulation. The mean terminal half-life of intravenous UNITROPIN in normal adults is 0.4 hours, whereas subcutaneously administered UNITROPIN has a half-life of 3.0 hours in GHD adults. The observed difference is due to slow absorption from the subcutaneous injection site.
The mean clearance of subcutaneously administered UNITROPIN in 16 GHD adult patients was 0.3 (+/- 0.11) L/hrs/kg.
Pediatric: The pharmacokinetics of UNITROPIN are similar in GHD pediatric and adult patients.
Gender: No gender studies have been performed in pediatric patients; however, in GHD adults, the absolute bioavailability of UNITROPIN was similar in males and females.
Renal or hepatic insufficiency: No studies have been conducted with UNITROPIN in these patient populations.
Carcinogenesis and Mutagenesis
Carcinogenicity studies have not been conducted with UNITROPIN. No potential mutagenicity of UNITROPIN was revealed in a battery of tests including induction of gene mutations in bacteria (the Ames test), gene mutations in mammalian cells grown in vitro (mouse L5178Y cells), and chromosomal damage in intact animals (bone marrow cells in rats).
UNITROPIN lyophilized powder was compared with placebo in six randomized clinical trials involving a total of 172 adult GHD patients. These trials included a 6month double-blind treatment period, during which 85 patients received UNITROPIN and 87 patients received placebo, followed by an open-label treatment period in which participating patients received UNITROPIN for up to a total of 24 months. UNITROPIN was administered as a daily SC injection at a dose of 0.04 mg/kg/week for the first month of treatment and 0.08 mg/kg/week for subsequent months.
Beneficial changes in body composition were observed at the end of the 6-month treatment period for the patients receiving UNITROPIN as compared with the placebo patients. Lean body mass, total body water, and lean/fat ratio increased while total body fat mass and waist circumference decreased. These effects on body composition were maintained when treatment was continued beyond 6 months. Bone mineral density declined after 6 months of treatment but returned to baseline values after 12 months of treatment.
HOW SUPPLIED AND HANDLING
UNITROPIN lyophilized powder is available in the following packages:
5 mg multi-dose vial – 1 vial per box. After reconstitution, each UNITROPIN vial delivers 5mg (approx. 15 IU). Supplied with bacteriostatic water ampule as a solvent.
Except as noted below, store UNITROPIN lyophilized powder under refrigeration at 2 C to 8 C. Do not freeze. Protect from light.
Unigen Life Sciences Ltd.
ING Tower 6/F, 308 Des Voeux Road


The Features section of Brig, Stirling University's student newspaper.
Read this informative article on the rise of STIs in student populations, and what to do about them – accompanied by original illustration by Kristina Hnizdilova.
Let's take a look back at those who forged the path for women of all backgrounds, to adventure out and explore the world alone.
LGBT society's Asexual Rep, Stephanie Hogg talks about her experience and views on living asexually.
Stirling University Challenge Treks – Everest Camp or Iceland?
Join Stirling RAG's charity initiative by conquering some of the most beautiful landscapes known to man.
New regulations for manufacturers to create sound for electric cars have been mandated; but until 2019, our behaviour in traffic may have to change.
Is a female Doctor exactly the regeneration the TV show needs?
Brig writers Stuart Graham and Cameron Watson debate whether a female Doctor is the right move for Doctor Who to make right now.
Brig editor Stuart Graham reflections on Mental Health May and what the whole month has meant for him.


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L'Union Sportive Athlétique plus couramment abrégé en US Athlétique, est un ancien club marocain de football fondé en 1920 et disparu en 1956 (après l'indépendance du pays), et basé dans la ville de Casablanca.

Histoire
Les historiens considèrent l'"Union Sportive Athlétique" abrégé en l'"USA" comme un club mondial car il comprenait à Casablanca, des joueurs de différentes nationalités attirés par le sport et le football en particulier. Pendant les années vingt, il a réussi à contrôler le championnat local qu'il l'a remporté en 1927, 1929 et 1947, ainsi qu'il a été également vice-champion plus de dix fois.

C'est avec l'USA où a été l'apparition des premiers joueurs marocains dans les clubs de la Ligue. L'un de ces joueurs n'est autre que Père Jégo. Après avoir été le tout premier bachelier de l'histoire du Maroc, le Père Jégo s'est découvert une passion pour le football en allant étudier en France en 1919, il rentre au Maroc en 1922, où il intègre les rangs de l'Union Athlétique. Quelques décennies plus tard, son génie footballistique sera reconnu comme entraîneur et son nom restera pour toujours associé au Wydad AC avec qui il a gagné presque tout.

En 1948, l'équipe parvient à atteindre la finale du Championnat d'Afrique du Nord après avoir écrasé sur son chemin de nombreux clubs tunisiens et algériens, au stade philip il perd la finale face au grand Wydad AC.
Un certain nombre de fans de football à Casablanca se souviennent fièrement du match que l'USA a remporté contre son premier rival l'Union sportive marocaine à la fin de 1947, avec un score record de 13 buts contre trois.

Palmarès et statistiques

Football

Juniors
 Championnat du Maroc - Division d'Excellence (Juniors) (1)
 Champion : 1947

 Ligue des champions de l'ULNA (Juniors) (1)
 Champion : 1947

Cadets
 Coupe Marcel Cerdan (1)
 Vainqueur : 1952

Ping-pong
 Championnat du Maroc :
 Champion : 1946

Personnalités

Présidents

Entraîneurs
Loulich

Joueurs emblématiques

Parmi les personnalités emblématiques du club, le gardien légendaire de l'équipe Idriss El Tayari, natif de Mohammedia, et Mustapha Bettache, ainsi que Mohamed Belmahjoub, frère d'Abderrahman Belmahjoub.
L'attaquant Haj Jilali Choukri (ex entraineur de l'Etoile Jeunesse Sportive de Casablanca).

Infrastructures
Avec le Stade Philip, l'équipe possédait aussi un centre sportif d'entraînement où l'équipe A et les autres catégories de jeunes effectuaient leur entraînements. Après la dissolution du club, le terrain a été attribué au Wydad Athletic Club.

Image et identité

Couleurs et évolution du blason

Rivalités

Affluence et supporters

Notes et références

Club de football disparu au Maroc
Club de football à Casablanca
Club de football fondé en 1920
Club de football disparu en 1960

redpajama_set_name: RedPajamaWikipedia


text:
Yeshivas Beis Menachem Mendel (Tzeirei Hashluchim)
At the Kinus Hashluchim 5757, Rabbi Aryeh Leib Kaplan ע"ה – who has been appointed and sent by the Rebbe to re-establish the Chabad settlement in Tzfas – attended a workshop for Shluchim on the subject of Chinuch. Participants shared their personal experiences, their views and frustrations pertaining to the various challenges associated with raising Chassidishe children in a Shlichus environment.
Many Shluchim articulated their utter frustration and disillusionment with the exorbitant tuition fees that Yeshivos were demanding. Drowning in bills associated with their פעולות, these Shluchim felt trapped in a system that could not accommodate their own growing families ka"h and their inability to pay steep fees for three, four, five or more children attending yeshivos simultaneously.
Without hesitation, Rabbi Kaplan stood up. He announced that he would set up a yeshiva in Tzfas that would cater to the specific needs of the children of Shluchim and the financial considerations of their parents.
Rabbi Aaron Lazer Ceitlin ע"ה – one of the Shluchim which were sent in groups to Tzfas (and Yerusholayim), in the year 5736 – was a participant at the workshop. Upon hearing Rabbi Kaplan's statement, he was stunned. "Why does he need this? He is so pressured with his own financial worries. Why does he encumber himself with yet another mosad?" Privately, he believed these words to be wishful thinking.
Yeshivas Tzeirei Hashluchim opened its doors for the 5758 school year. Rabbi Kaplan took advantage of available space in the Yeshiva Gedolah, hired Rabbi Sholom Ber Hertzel as Rosh Yeshiva and set the tuition at only two thousand dollars a year! The yeshiva saw immediate success.
Thanks to the generous and faithful support of Rabbi Hillel Dovid Krinsky and Collel Chabad, headed by Rabbi Sholom Duchman, the yeshiva is now housed in the once-being Pisgah Hotel and can accommodate over one hundred bochurim. Any financial assistance provided by the Israeli government is passed on to the yeshiva, helping the tuition remain low.
In 5773, Rabbi Zalman Kaplan – who served as Shliach and spiritual leader at the Montreal Torah Center – took upon himself the responsibility of leading the Yeshiva and towards the 5774 school year moved with his family to Tzfas as Rosh Yeshiva.
In a letter to the Shluchim, Rabbi Zalman Kaplan wrote: "After difficult deliberations, I followed the Rebbe's counsel of asking three Rabbanim who unanimously directed me to move from Montreal this year and open the Tzfas yeshiva for the benefit of Shluchim families and for the sake of Chabad children's Chinuch."
Indeed, the yeshiva has grown בגשמיות וברוחניות. Yeshivas Tzeirei Hashluchim is well-known for its high standards in learning of נגלה and חסידות. The talmidim have access to a unique and supportive staff of
מגידי שיעורים, משפיעים and Shluchim who pay special attention to their learning, עבודה and Chassidishkeit of each of the individual bochurim, preparing them for their roles as future Shluchim and Chassidishe Yidden.
Four years since the reopening of the yeshiva has ב"ה experienced continued growth and success. Over this short period, over 150 students have studied in the Yeshiva, and our alumni are counted among the outstanding Temimim in Chabad Yeshivas worldwide.
In tribute of this notable success, and the twentieth anniversary since the founding of the Yeshiva by Rabbi Aryeh Leib Kaplan, it has been decided to dedicate the name of the Yeshiva to the Rebbe זי"ע, and is now called "Yeshivas Beis Menachem Mendel Chabad."
The yeshiva is currently undergoing a project of building a new zal and renovating the dormitories.
(Re-edit of an article written by Frayda Kaplan - N'shei Chabad Newsletter, April 2008)


My daughter is dec 2010 born, and I'm looking for SBOA/Velammal/DAV/Everwin. Please let me know the application issuing date.....And also suggest me some best CBSE schools..
Please note other CBSE schools - Maharishi vidya mandir, Landy Andal, Bhavans vidyashram, chennai public school..Most of the schools are scheduled to issue application form on November last week..
I am a new joiner on this site and am looking for good CBSE schools for LKG admission .
LKG appln was given in CPS on Dec 12th and 13th and the interview is going on. U can contact CPS junior academy office near anna nagar rountana.
Then u have to try to get admission in some other school.
Hi I am new to this thread.. Can anyone confirm when DAV mogappair girls CBSE school is issuing application for LKG. Which school is better to go whether DAV or Chennai public school?
Heard they want to pay some fees to block the seat? any updates?
Even i attended the interactive session with my kid.Did any one get the results or any information about whether the admission list is out?
Which school starting thier new branch at Mogapayer? Please update me. I am staying at perambur location. Looking for SBOA or CPS my kids DOB 30th Mar 2011. I have take application in Everwin Kolathur, I dont know about school.
compared to everwin, KRM public school in perambur and vivekananda perambur and vivekandanda kolathur is good.


This week sees the release of The Flash #14, part two of Gorilla Warfare, by Francis Manapul and Brian Buccellato. Preview at CBR.
Gorilla Grodd's more powerful than ever, and the Flash is completely outmatched! Who will give their life defending Central City against the ape invasion?
ComiXology's digital backissues have paused in releasing the early 1990s Flash, but Impulse is still going, with issues #37-38 by William Messner-Loebs and Craig Rousseau.
Impulse #37 parodies the grim-and-gritty 90s excess as Bart encounters the Glory Shredder, a vigilante who takes his anti-crime crusade too far.
In Impulse #38, a rising river threatens to flood Manchester, Alabama. Can two speedsters and a handful of quirky villains make the difference as the townspeople struggle to save their home?
This entry was posted in Out This Week and tagged Barry Allen, Bart Allen, ComiXology, Gorilla Grodd, gorilla warfare, Impulse on November 27, 2012 by Kelson.
Comic Book Resources has a preview of Flash #14, part 2 of Gorilla Warfare. The issue by Francis Manapul and Brian Buccellato arrives in stores next Wednesday.
This entry was posted in Flash News and tagged Gorilla Grodd, Preview on November 23, 2012 by Kelson.
ComiXology has paused in its digital Flash reprints (last week their library caught up with a large chunk of previously-released issues), but Impulse is still going.
Impulse #35: Part 2 of The Devonian Age, in which a villain alters history to make himself ruler of the world…but the timeline isn't exactly stable, as Impulse and Max Mercury find out.
Impulse #36: Bart and his friends testify in court about the events a few issues back when they caught a group of criminals dumping toxic waste outside town. Also: Impulse shaves his head, because, y'know, it seemed like a good idea at the time.
This entry was posted in Out This Week and tagged Bart Allen, ComiXology, Impulse on November 21, 2012 by Kelson.
This week's ComiXology back-issues include Flash #72-73 and Impulse #33-34.
The Return of Barry Allen itself is already available, launched during the Flash 101 sale last year, as is the following storyline, "Back on Track," in which Wally teams up with Nightwing and Starfire. That means that as of this week, the first 83 issues of Wally West's Flash series are all available online. No doubt next week ComiXology will jump ahead to #84.
I don't remember anything about Impulse #33, and as fun as the cover is, it doesn't jog my memory of the contents. The title is "Time Out," so it might be the one where Bart's school's new guidance counselor calls Max and Helen in to go over Bart Allen's guardianship. (It's funnier than it sounds.) ComiXology describes it as featuring the return of White Lightning, and the kids dealing with the missteps of the school's new social worker.
Impulse #34 is the first half of "The Devonian Age," a story in which Bart and Max Mercury get caught up in a time travel experiment gone wrong (don't they always?) and have to try to repair history from the butterfly effect.
This entry was posted in Out This Week and tagged Bart Allen, ComiXology, Impulse, Max Mercury, Thanksgiving, Wally West on November 13, 2012 by Kelson.


text:
Tag Archives: emf
Pizza place left in the dark after installation of unwanted smart meter
Wednesday, December 28th 2016, 6:49 pm EST
Thursday, December 29th 2016, 7:14 am EST
By Jerry Askin
MEMPHIS, TN (WMC) –A dispute over smart meters left customers and workers at a local pizza place in the dark Tuesday night.
Despite the lights being back on and burning bright Wednesday at Broadway Pizza, the business was left in the dark for almost 24 hours after a utility worker installed a smart meter.
The owner of the business said they never requested a smart meter.
"It's very frustrating," Broadway Pizza owner Dewana Ishee said. "We're still in the dark, hopefully by some time today they'll get us turned back on."
Ishee spent part of Wednesday in the dark with no customers, no deliveries, and lost revenue.
"All because they did something we asked them not to do," she said. "We specifically told them not to put a smart meter on our business."
But, utility workers did install a smart meter outside her business Tuesday. That's when the lights went out.
Surveillance video shows a worker putting in a meter around lunch time. During the installation of the meter, she said her restaurant lost power. She said once the utility worker realized he made a mistake, he used a jumper cable to try to correct the problem.
"Now we've got a full restaurant again because we've been jumpered off and they're going to pull the plug in the middle of people taking bites of their food," Ishee said.
Now, she's upset that she spent hours without power and without business.
Memphis, Light, Gas and Water (MLGW) said if they didn't want a smart meter, then there is a process to not have one installed.
"If a customer does not want a smart meter, they just need to follow the process of letting us know," MLGW spokesperson Gale Jones said.
MLGW said they send out letters a month before installing any smart meter and customers must call in to opt out. They said a letter was sent to Broadway Pizza on November 1.
"We have nothing on record to show that this company opted out," Jones said.
But, Broadway Pizza said they never received a letter.
Ishee said the outage put her business in the dark during their busiest time of year.
"Our main source of income is between December and March," Ishee said.
Ishee said she didn't want the smart meter because she supports meter readers.
MLGW said once you receive a letter regarding a smart meter, you must call in to opt out. The number to call is 901-544-6549.
Copyright 2016 WMC Action News 5. All rights reserved.
http://www.wbrc.com/story/34144088/pizza-place-left-in-the-dark-after-installation-of-unwanted-smart-meter
By Sandaura • Posted in Smart Meter News Updates	• Tagged cancer, cell towers, emf, heart issues, hypersensitivity, NOISE, PLC, pollution, privacy, radiation
Smart electricity meters can be dangerously insecure, warns expert
Hackers can cause fraud, explosions and house fires, and utility companies should do more to protect consumers, conference told
Smart meters are frequently dangerously insecure, a security expert has warned.
Alex Hern in Hamburg
@alexhern
Thursday 29 December 2016 09.51 ESTLast modified on Thursday 29 December 2016 10.50 EST
Smart electricity meters, of which there are more than 100m installed around the world, are frequently "dangerously insecure", a security expert has said.
The lack of security in the smart utilities raises the prospect of a single line of malicious code cutting power to a home or even causing a catastrophic overload leading to exploding meters or house fires, according to Netanel Rubin, co-founder of the security firm Vaultra.
"Reclaim your home," Rubin told a conference of hackers and security experts, "or someone else will."
If a hacker took control of a smart meter they would be able to know "exactly when and how much electricity you're using", Rubin told the 33rd Chaos Communications Congress in Hamburg. An attacker could also see whether a home had any expensive electronics.
"He can do billing fraud, setting your bill to whatever he likes … The scary thing is if you think about the power they have over your electricity. He will have power over all of your smart devices connected to the electricity. This will have more severe consequences: imagine you woke up to find you'd been robbed by a burglar who didn't have to break in.
"But even if you don't have smart devices, you are still at risk. An attacker who controls the meter also controls the meter's software, allowing him to cause it to literally explode."
Rubin said many of the warnings were not hypothetical. In 2009 Puerto Rican smart meters were hacked en masse, leading to widespread billing fraud, and in 2015 a house fire in Ontario was traced back to a faulty smart meter, although hacking was not implicated in that.
The problems at the heart of the insecurity stem from outdated protocols, half-hearted implementations and weak design principles. While the physical security of smart meters is strong – "trust me, I tried" to hack in that way, Rubin said – the wireless protocols many of them use are problematic.
To communicate with the utility company, most smart meters use GSM, the 2G mobile standard. That has a fairly well-known weakness whereby an attacker with a fake mobile tower can cause devices to "hand over" to the fake version from the real tower, simply by providing a strong signal. In GSM, devices have to authenticate with towers, but not the other way round, allowing the fake mast to send its own commands to the meter.
Worse still, said Rubin, all the meters from one utility used the same hardcoded credentials. "If an attacker gains access to one meter, it gains access to them all. It is the one key to rule them all."
Inside the home, too, the communications are rendered insecure by outdated standards and bad implementation. Almost all smart meters use the Zigbee standard to speak to other smart devices in the home.
Zigbee, which dates from 2003, is a popular home automation standard, used for controlling everything from lightbulbs to air conditioners. But it is so convoluted, due to the vast array of devices supported, that it is almost better to think of it as 15 different standards, each of which vendors can choose to implement as they see fit.
"This unique situation is so difficult to implement, venders actually choose what they want to implement. And when they choose what to support, they more often than not skip security," Rubin said.
Other weak security decisions made by vendors include:
Encryption keys derived from short (often just six-character) device names.
Pairing standards with no authentication required, allowing an attacker to simply ask the smart meter to join the network and receive keys in return.
Hardcoded credentials, allowing administrator access with passwords as simple and guessable as the vendor's name.
Code simplified to work on low-power devices skipping important checks, allowing nothing more than a long communication to crash the device.
"These security problems are not going to just go away," Rubin said. "On the contrary, we are going to see a sharp increase in hacking attempts. Yet most utilities are not even monitoring their network, let alone the smart meters. Utilities have to understand that with great power comes great responsibility."
Smart meters come with benefits, allowing utilities to more efficiently allocate energy production, and enabling micro-generation that can boost the uptake of renewable energy. For those reasons and more, the European Union has a goal of replacing 80% of meters with smart meters by 2020.
https://www.theguardian.com/technology/2016/dec/29/smart-electricity-meters-dangerously-insecure-hackers
By Sandaura • Posted in Smart Grid Syndrome Testimonials, Smart Meter News Updates	• Tagged AMI, cell towers, emf, heart issues, hypersensitivity, microwave, noise pollution, radiation
Halting Smart Meter Installation in Massachusetts and Beyond
Spirit of Change Magazine
Patricia Burke
In Fairfax, California, the utility company installed microwave transmission devices without informing the community, and many EHS individuals in Massachusetts perceive the same dynamic occurring in the Commonwealth. Symptoms of electromagnetic sensitivity can include indigestion and nausea, extreme vertigo, eye dryness and skin problems, headaches, nosebleed, overheating, exhaustion, depression, sleep disorders, aggression, focusing issues, fertility challenges, internal bleeding, and brain fog. The Berkshire-based blog http://www.sandaura.wordpress.com documents complaints from residents adversely affected by the hum of pulsed 217 Hz radio frequency emanating from the power lines, the noise of which represents a violation under Massachusetts General Law.
http://www.spiritofchange.org/politics-community/halting-smart-meter-installation-in-massachusetts-and-beyond
By Sandaura • Posted in Smart Meter News Updates	• Tagged emf, microwave pollution, noise pollution, RF, smart meter opt out


text:
New Design Guide Offers Stormwater Solutions
Josh Cohen June 15, 2017
(AP Photo/Peter Morgan)
From New York to Charlestown, South Carolina, to Oak Creek, Wisconsin, to Atlanta, cities and towns all over the U.S. are trying to figure out better ways to manage stormwater. Climate change impacts, including more frequent and intense storms and extreme flooding events, are stressing existing stormwater infrastructure leading to backups, flooding and increased pollution runoff.
How (and Why) the Federal Government Should Help American Cities Manage Storms and Rising Seas
How Two Smaller Legacy Cities Are Adopting Green Infrastructure
Bringing Cleaner Water, Green Jobs to D.C.'s Suburbs
Which Cities Are On the Climate "A-List"?
Rather than investing in expensive upgrades to their grey infrastructure — traditional pipes, tanks, water treatment plants — many of the above cities are experimenting with green infrastructure such as permeable soils, plants, bioswales and retention ponds that filter pollutants out and release water back into aquifers.
"The conventional method is to just convey stormwater off the street and into sewers and treatment plants. It's very expensive and separates water from natural ecology. Sustainable stormwater infrastructure captures and re-uses the water," says Corinne Kisner, director of policy at the National Association of City Transportation Officials (NACTO).
Kisner co-authored NACTO's new Urban Street Stormwater Guide. In it, NACTO makes the case that green stormwater infrastructure can be combined with transportation infrastructure projects to help cities meet their stormwater management goals, save money and, in some cases, make streets safer for walking and biking. The book looks at case studies from cities around the U.S. and provides guidance for building green stormwater infrastructure in transportation corridors.
Stormwater management is new territory for NACTO, which has previously published design guides for urban streets with transit and bikeways, but Kisner argues it's a logical step.
"Given the amount of space streets take up in cities and the fact that streets create a ton of impervious surface space, they are an opportunity to make big changes in a city's ecological impact," she explains.
The guide provides a variety of green stormwater infrastructure designs for cities to implement, from major capital projects to low-cost neighborhood intersection treatments.
When St. Paul, Minnesota, built an 11-mile, $957 million light rail extension, it included $5 million in green stormwater infrastructure to reduce runoff and improve water quality. They used rain gardens, bio-retention planters, permeable paver stones and tree trenches. The green infrastructure mitigates approximately 50 percent of stormwater runoff, easing the burden on the traditional sewer system.
On the other end of size spectrum, the guide looks at a $420,000 intersection project in Philadelphia. The city eliminated a slip lane that enabled high-speed right hand turns from Stenton Avenue to East Washington Lane. In its place, they built a rain garden that reduces the amount of impermeable asphalt. "It's more enjoyable to walk because the garden is nice to look at. It's safer because the crossing distances are shorter," says Kisner.
The guide has suggestions for permeable pavement applications, using rain gardens as barriers for protected bike lanes and curb bulb outs, replacing center medians with bioswales, installing bioswales on sidewalks and around bike-share stations and more.
"Cities have very limited street space," Kisner says. "Green stormwater infrastructure helps find ways to integrate everything a city wants within the same physical street space."
Perhaps unsurprisingly, NACTO says funding and the need for cross-departmental collaboration are two of the biggest challenges for cities interested in green stormwater infrastructure experiments. The city staff working on transportation is rarely in the same department as staff dealing with stormwater. Solving the latter problem can actually help the former, however.
In many of the guide's case studies, cities were able to access stormwater and transportation grants for the same project.
"Part of what our guidebook steering committee got excited about was the opportunity to leverage one project with another and leverage transportation funding with stormwater funding to get a better project over all," says Kisner.
She continues, "Cities are recognizing that climate change is our most urgent issue and are looking to make a difference with climate mitigation. Changing how we move around the city is important for mitigating greenhouse emissions. And changing stormwater infrastructure is important for mitigating climate impacts."
Josh Cohen is a freelance writer in Seattle. His work has also appeared in The Guardian, The Nation, Pacific Standard and Vice.
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Tags: urban design, climate change, stormwater management
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Does money keep you up at night?
The O'Jays got it right, "Don't let money rule you". Yet, in our age, money does rule business, and it can make the difference between success and ruin.
Join SMSBF on March 6th, from 8:30 am to noon at the MSU Detroit Center, for "The Green that Grows: Financing and Funding for Land Based Businesses".
"The Green that Grows" continues SMSBF's commitment to supporting sustainable agriculture, locally based food systems and triple-bottom line businesses in Southeast Michigan.
Moving beyond the mid-scale level and expanding a farm or other land-based business is a real challenge. Understanding funding and financing options is not easy, especially for those who'd rather be working in the fields, than studying spreadsheets.
Those who are passionate about land-based businesses know the pressing needs and challenges, and they're striving to meet them. We may be doing everything we can to use sustainable methods for our products and services, but are we doing what we can to ensure our businesses are sustainable? Urban agriculturalists, small farmers, organic and sustainable farmers, agriculture related business leaders and anyone interested in triple bottom line business practice will not want to miss this event.
Limited Spaces Available. Reserve Your Spot Early!
Savannah specializes in connecting current and prospective farmers with opportunities to help them realize their farm business goals.
Over the last two years, Savannah's work has helped her understand how federal agencies, state agencies and partner organizations function together to provide resources and safety nets for farms of all types, shapes and sizes. She uses this knowledge to help farmers and ranchers understand how to more easily access these programs, should they choose.
Savannah holds a Juris Doctorate, Master of Liberal Studies in American Culture, Master of Public Administration, and a Bachelor of Science in Biology and Chemistry. When not serving with the USDA, she operates a small, family-owned sheep farm in central Michigan.
Dean is involved in cover crop, soil health and organic agriculture research and education. Farmers and commodity groups are an integral part of his projects and programs. He is a member of the Midwest Cover Crops Council Executive Committee. He is the Sustainable Agriculture Research and Education (SARE) Coordinator for the state of Michigan.
He has a Ph.D. in Environmental Geosciences and Biosystems and Agricultural Engineering and a B.S. in Agricultural Engineering from MSU. Prior to returning to MSU for graduate study, he had a 20-year career with the Kellogg Company.