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Koch Network Spent Nearly $400 Million In 2015
01/31/2016 12:08 am ET Updated Jan 26, 2017
Carlo Allegri/Reuters
David Koch arrives at the Metropolitan Museum of Art Costume Institute Gala Benefit in New York City, May 5, 2014.
The Koch brothers' donor network spent close to $400 million last year, and is on its way to spending an unprecedented $889 million supporting right-wing politics and causes during the 2016 cycle.
Read more on The Hill
Charles Koch David Koch Koch Network


It's been tens years since I started my first blog in 2006! In the mean time, I went through undergrad, masters, marriage and have been working full time for almost 4 years. Looking back, I am really glad that I kept a (not so complete) record of what I made, what I bought, what I suffered and what I accomplished. Indeed, I also used to write about life in QQ zone and MSN space. I also occasionally (and still) post in Weibo, WeChat Moments, Facebook and Instagram. Once in a while I would enjoy pinning for 30 minutes in Pinterest. Hmmm... Seems like I am so keep up with the social media! The only place that I never have an account is Twitter.
Today I hang out with an Instagram friend at a Starbucks near my house, and we talked a lot about the knitting community (while finishing our socks). I found I have missed a lot about the "hit" stuffs and designers in the knitting world! Just now, I went through a Toronto Yarn Shop blog that I created in 2006, and was surprised to see many of the local yarn shops that I visited 10 years ago have disappeared. Maybe it's time to refresh the blog entries and put in new ones (and include fabric shops). If you are in the GTA area, please share with me your favorite shops and I will take a visit.


Last time those two played was about 5 years ago, 2008 in Wolverhampton, I would guess probably not a long time after Cops arrived in the UK. They had a good 5 setter battle, 78m. So LJ didn't I'm sure expected an easy ride, although I feel that the glass court was more familiar to the Dutch than to the South African.
One thing I've noticed with Steve, like I did with the other South Africans I saw playing, Rodney, Clinton, is the true belief that they can win. That they can do it. And their utmost ability to give it all on there, every time, every point, every rally. It's an immense quality, and we saw it again tonight.
LJ played a very strong game, but Steve, with no pressure and that belief I told you about, run a lot, retrieved even more, found some lovely length, and surprised LJ with some gorgeous volley drop shots and a few kills. Both games could have gone either way really, but LJ takes the first one, and Steve the second.
LJ, with Neil Harvey, his former coach in his corner, speeded up the pace in the third, and Steve's legs, that had been put to a heck on a use during those first two, just couldn't follow in the 3rd. And in the 4th, having had a little rest, he tried again to give it a last push, but by that time, LJ was extremely confident, even more accurate, and didn't allow his opponent to even dream about going into a decider.
"With the point a rally system, you can stay close, but at some point, if you push hard and stick to your game plan, it pays off in the end.
"It's a bit of a bitter sweet feeling. It's my first time ever in the second round of any major event, so it's very big for me. But I'm very happy with the first two games, and not happy with the following two games!
Not sure that Tom was ready for Nick today, and after the first game, where the young man was a bit overwhelmed by the world number one's pace and accuracy, it looked like we were heading for an easy 3/0.
Nick kept on making Tom's life terribly difficult in the second, and what that boy had to do/attack/retrieve to score a point is nobody's business!!! But Tom did surprise me I have to say in that second game, by leading score wise all the way, by his authority and his "calm", patience, and accuracy, mixing excellent length with perfect short game.
At 4/4 in the second, we had the "shoe lace gate", where Tom stopped the rally as he had his shoe and shoe lace damaged by Nick he said. So a let was given, much to Nick's astonishment. Would be interesting to study the video to see what exactly happened there!
And to be honest, Tom just didn't see much of a ball in that third. Nick outplayed him completely, and did so up to 5/1 in the 4th! There we had a few interruptions, video reviews (two in the same point), and again, Tom seemed to benefit from that stop!
Coming up to 4/5 then 6/7, he really started believing in his chances again, and it took Nick's extreme hard work and a last biiiig push to shrug off that hungry young man….
"Tom is at a stage of his career, he just got into the top 16, had his first selection for the English Team at the Europeans, he is very hungry for the scalp of a top player.
There were a couple of stoppages I think that suited him more than me, the shoe lace incident for example – mind you, he was running pretty well with it, so at the end of the second, I told him I wanted it back. It's the most ridiculous call, to give a let because he broke his shoe lace!!!
I had to stand firm in the third, got that one, and in the fourth, we had a few reviews, that broke my rhythm a bit, and it was tough all the way through.
"I think I lacked a bit of maturity in the third, I got a bit excited after taking the second game, being at 1/1, and speeded up the pace and volleyed too much. Which is my natural game, but suits Nick too much, and that gave him the advantage, I was not patient enough. So, disappointed.
For the shoe incident, he trod on my feet, maybe he didn't feel it, but he broke my shoe, and when it was re-laced, we had to drop three holes that were broken. So it was a let any day of the week.
If I had that maturity, I think I could have asked him questions. I pushed him, but not hard enough. I have beaten players around 9, 10 in the world, and I believe that I can now beat the top 8 guys. For the past 5, 6 months, I feel that my game has improved, but this summer, I need to work very hard with Chris Robertson to improve my game.
We are working in particular on subtleties of the game, like the way I'm striking the ball, using the face of the racquet, to try and get a better quality of my shots, and then being able to use my physicality to a better end. Once I've done that, I'll be ready for next season, and things should be fine.
Getting my first selection for the England team gave me a lot of confidence, to come and see the way the players like Nick, James, Peter prepare, to have some insight was such an incentive. Hopefully, there will be many more selections.
Another Englishman went through to the quarters as Peter Barker came from a game down to beat Speedy Indian Saurav Ghosal, the sixth seed imposing his game for a 7/11, 11/2, 11/6, 11/6 win in just short of an hour's play.
He moves very fast, but then again, I would too if I was 50kg! Only joking. Not only he moves very fast, but he is strong as well, in, out, in, out. Really solid. He hit a few tin, we like when the opponent hits the tin.. I did my best to frustrate him I have to say….
"A very good first game. Like he said, I was getting it by him well, but after that, I couldn't do it as consistently as I did in the first. Plus, I made a few errors, but only just, I just clipped the tin, it was the right shot, if it had been a good shot, I would have won the point…. So frustrating.
He was getting ahead of me more than I was, and he played very well, he didn't have any weak moments. I really enjoyed the match, it was a clean match, fair, just very disappointing in the end.
Second seed Gregory Gaultier raced through a quickfire match against qualifier Jonathan Kemp to claim the last remaining quarter-final spot, the 2007 champion taking on his shotmaking opponent and bettering him at it.
Happy with the way I played, I was aggressive on the ball, without giving him too much in the centre, because he's got some unbelievable racquets skills, so anything you play "that much" away from the wall, he kills it.
I'm really pleased with the way I'm playing, I had a good 3 4 weeks of hard training, after a long period where I was suffering from hay fever and couldn't play at all. So I spent some time training with Azlan, I'm feeling good now.
And now that the trees are grown finally, that the flowers are gone, I can breathe easily! Now, I'm going to look back at my performance tonight, analyze what I did well and not so well for my match tomorrow.
As far as I know, those two players only played once, it was during the World Teams event, and Camille won apparently comfortably. So confidence was high when she got on court, while Jacklyn looked a bit nervous and not completely in the match to start with.
Now, the New Zealander didn't reach the top 20 by accident, so that quick first game, 5m, was not going to be a reflection of the whole match, I was sure of that. And in the second game, as expected, she came out blasting, moving much better, and forcing Camille to attack from a less perfect position than in the first game.
That second game was really close, and the rallies very disputed. Camille got the upperhand, 10/7, game ball, and went for too much too early. I could hear her coach saying quietly for himself, "you've got the time, no hurry". Jacklyn scored twice to come back and threaten the French girl, 9/10. But with a lovely backhand crosscourt nick, Camille closed the game, 11/9, and in fact the match, as in the 3rd, Jacklyn made a few errors, and never threatened again her opponent.
"This cold court suits my game really, and I think that the length is the key to this court. Today, I was able to find my length and would really use it to win the point at my first or second drop shot attempt.
I really don't mind the open venues like that, as I find it easy to focus, I like the court very much, only thing, you've got to concentrate a bit more to see the ball on this one, but I really enjoy the venue.
British national champion Laura Massaro had two tough opening games, and had to save game balls in both as she took the lead against Natalie Grinham 15/13, 12/10, much to Grinham's disappointment as decisions went against her at the business end of both games.
Massara came out strongly in the third, neutralising Grinham's pace and retrieving with a series of controlled rallies where she put the ball away nicely. A 9/2 lead all but sealed her passage into the quarters despite a late fightback from the Dutch former world number two, and she finished it off 11/6 with a dropshot to the front that even Grinham couldn't reach.
"It's tough on here than it looks, it's quite dead and if you get it to the back corners it's difficult to dig it out.
"I stayed pretty solid, countered when I got the opportunity but it's tough, she's very fast$and goes short such a lot, you have to be on your toes all the time.
If Joelle was a bit nervous to start the match, and kept making a few errors too many (an average of 4 per game), she never panicked, stayed head strong, and never stopped trying/believing.
First and third game were all about Rachael hitting some stunning volley drop shots, from the centre, from the back, from outside the bleeping court, and lobbing to perfection to get out of trouble.
The second and fourth, well, Rachael dropped a bit her length, made a few wrong shot selections, and found the tin more than the wining shot.
The fifth was a classic! Joelle started well, 5/2, Rachael coming back at 6/6. 7/7. 8/8. 9/9. 10/10. 11/11. 12/12. 13/13. That's to give you an idea how close they were!
"I was a bit nervous, such a stage as this one, plus Rachael is such a tough competitor…. I really didn't comfortable on there to start with, the occasion got the better of me, and after the end of the 1st I was really annoyed with myself. But I hang in there, dug in, and tried to keep the ball off the tin.
In the past, I probably wouldn't have hang in there and flagged it in, so it's a very positive side for me that I could stay in there.
It's always difficult playing a friend, especially a room-mate," said Nicol David after her 11/7, 11/7, 11/3 win over Samantha Teran. The Mexican battled, as she does, but the world number one was always in charge and by the third game was looking very comfortable as she tested out some of her repertoire of shots.
"I had a good practice on the court this morning to get used to it early, and I watched the other matches and saw that the ball wasn't moving very well so I knew I had to get my eye in early. It's difficult playing a friedn, she's been sharing my house in Amsterdam and we've been rooming and training together over here, but I really wanted to get it done today. She wanted to win of course, but I got into the match quicker, and I wanted it more than she did!
The first match of the day saw France's Camille Serme consolidate on a flying start as she beat Kiwi Jaclyn Hawkes in a quickfire three games. Dominant in the first game, Serme got the better of a close second game before racing through the third to secure a quarter-final spot.
After two tough opening games were shared, Laurens Jan Anjema powered through the next two as Steve Coppinger's wheels fell off, the Dutchman winning 12/10, 9/11, 11/2, 11/3 in just under an hour.
British national champion Laura Massaro also had two tough opening games, and had to save game balls in both as she took the lead against Natalie Grinham 15/13, 12/10. A 9/2 lead in the third all but sealed her passage into he quarters despite a late fightback from the Dutch former world number two.
"It's brutal on there," commented Massaro on the court conditions, "if you play the right game you can get people off quickly, but it can work the other way too and against someone as quick as Natalie you have to be constantly on your toes.
Defending champion Nick Matthewwas made to work hard by compatriot Tom Richards, who recovered from losing the first game 11/5 to take a 25-minute second game 11/8. Matthew, six year senior, exerted his authority from 4-all in the third and 5-4 in the fourth to complete the win in 68 minutes.
Defending champion Rachael Grinham (although it was back in 2009) exited the British Open at the hands of Joelle King in the first upset of the day. The first four games were shared with the girls taking it in turns to paly well, setting up a nailbiting decider which saw the Kiwi take it on her third match ball, having previously saved two.


I have a vintage Motobecane road bike made in France. This bike has been used. Please look over all picture. Still in very good condition. Avoorl crankshaft, Campagmolo derailleur components, the frame is marked B704. Tire size is 27" or 32-620. Serious buyers only. No scammers, no western union, cash deals only. Bike is being sold in as is condition.


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Q: When C#8 is released, on what frameworks will it run on? When C# 8 is released, will it be targeting .NET Core 3.x only or will it be able to target existing frameworks too? If so, which ones?

A: The answers to this question can only be links to the official announcements and blog posts. From Mads Torgersen's Building C# 8

Platform dependencies
Many of the C# 8.0 language features have platform dependencies. Async streams, indexers and ranges all rely on new framework types that will be part of .NET Standard 2.1. As Immo describes in his post Announcing .NET Standard 2.1, .NET Core 3.0 as well as Xamarin, Unity and Mono will all implement .NET Standard 2.1, but .NET Framework 4.8 will not. This means that the types required to use these features won't be available on .NET Framework 4.8. Likewise, default interface member implementations rely on new runtime enhancements, and we will not make those in the .NET Runtime 4.8 either.
For this reason, using C# 8.0 is only supported on platforms that implement .NET Standard 2.1.

We'll get more information at Build 2019. I wouldn't be surprised to hear there's a migration path for older code, especially now that .NET Core 3.0 supports WPF and Windows Forms

redpajama_set_name: RedPajamaStackExchange


You can save over 45% costs in a full portfolio QC and reduce the time taken for these reviews by over 30%, while maintaining the same quality.
As a correspondent, when you on-board bulk loan portfolios, you need to do a full portfolio QC to ensure that there are no bad loans in the portfolio. These pre-purchase reviews can be very time consuming and they can get pretty expensive as well.
What if you were able to save over 45% costs in a full portfolio QC and reduce the time taken for these reviews by over 30%? This will signify direct benefits in terms of margins and significant savings in time.
What steps can Correspondent lenders take to reduce the costs in pre-purchase reviews, reduce risk and complete this process much faster, almost 30% faster. We thought of 4 ideas that can provide quick ROI. Also, with no upfront investments involved, the correspondent lender virtually has no risk associated with these initiatives.
How can you speed up bulk processing and be 50% faster?
What can you do to ensure 99.5% accuracy?


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I'm Olen (28) from Market Rasen, Great Britain. I'm learning Norwegian literature at a local university and I'm just about to graduate. I have a part time job in a backery.


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text:
namespace rubinius {
  Thunk* Thunk::create(STATE, Object* self, Object* value) {
    Thunk* pe = state->new_object<Thunk>(as<Class>(self));
    pe->value(state, value);

    pe->execute = thunk_executor;
    return pe;
  }

  Object* Thunk::thunk_executor(STATE, CallFrame* call_frame, Executable* exec, Module* mod,
                                       Arguments& args)
  {
    Thunk* thunk = as<Thunk>(exec);

    if(args.total() != 0) {
      Exception* exc =
        Exception::make_argument_error(state, 0, args.total(), args.name());
      exc->locations(state, Location::from_call_stack(state, call_frame));
      state->thread_state()->raise_exception(exc);
      return NULL;
    }

    return thunk->value();
  }
}

redpajama_set_name: RedPajamaGithub


text:
import { Component } from '@angular/core';

@Component({
    templateUrl: './nested.component.html',
    styleUrls: ['./nested.component.css']
})
export class NestedComponent {}


As an experienced engineer, I struggle with the commit cadence and find it is a personal development style - others might commit more or less frequently than I do.
As mentioned, break up your features or tasks into branches. Commit often on your local/remote branch at crucial save points or to mark work in progress with commit messages that at are short but to the point.
When you are ready for a pull request and to merge to master, git rebase is your friend. This command allows you to squash your mini commits into a one nicely worded and descriptive commit about the changes you have made.


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IS ADUHELM SAFE? PATIENT DEATH REPORTED TO THE FDA
By Ariana M. Teng
Since the June 2021 "accelerated approval" of Biogen's Alzheimer's drug, Aduhelm, all eyes of the medical community, investors, and the public have been on the company to finalize the results of its Phase 4 confirmatory trial. As the results of the confirmatory trial were released by Biogen in early November 2021 at a conference for Alzheimer's research and development, the public also became aware of the first likely Aduhelm-related death.
What is FDA Accelerated Approval?
On June 7, 2021, Biogen's drug, Aduhelm, met "accelerated approval" requirements under regulatory standard 21 CFR 601.41 and was subsequently approved by the FDA.
According to the FDA's website, theAccelerated Approval Program "allow[s] for earlier approval of drugs that treat serious conditions, and that fill an unmet medical need" based on a predicted clinical benefit. One string attached to this program is that companies such as Biogen are required to conduct a Phase IV confirmatory trial to prove the drug's benefits. The drug remained on the market in the meantime for qualified patients with mild Alzheimer's disease.
Accelerated approval differs from FDA Emergency Use Authorization (EUA), the latter which was used to produce, approve, and distribute the vaccines for COVID-19. For consumers, one of the most harmful disparities between these two FDA processes is the extent of rigor to which each drug was tested and subsequently received approval.
For example, as exemplified in Biogen's clinical trials for Aduhelm, there were only approximately 3,500 study participants across Phases I-III of the study. In comparison, the Pfizer COVID-19 vaccine (BNT162b2) study collected data from 43,448 participants across Phases I-III.
Additionally, Aduhelm's efficacy had been statistically insignificant during Phases I-III. Its first and third studies concluded that "differences from placebo observed in the ADUHELM low dose group numerically favored ADUHELM but were not statistically significant." Its second study concluded that "No statistically significant differences were observed between the ADUHELM-treated and placebo-treated patients on the primary efficacy endpoint." In comparison, the Pfizer vaccine had a 95% demonstrated efficacy in preventing the SARS-CoV-2 virus.
What did Aduhelm's Phase IV Trial Conclude?
Phases I-III based their efficacy on the ability to reduce amyloid beta plaques in the brain—a fundamental pathophysiological characteristic ofAlzheimer's disease. However, for Phase IV, Biogen presented its findings based on a framework of the efficacy to reduce another protein consistent with the progression of Alzheimer's, tau.
Based on their data, "levels of the protein [tau] in participants taking Aduhelm dropped by 13-16% from the start of the study, compared to an 8-9% increase among those getting placebo." Additionally, Biogen concluded that "the gap of not taking the drug didn't seem to adversely affect the patients."
This calls their research methods and ethics into question since the framework they used to conclude efficacy between Phases I-III and Phase IV shifted, in addition to their claim that the absence of Aduhelm did not harm patients. For clinic trials, the research and development companies have the burden of proof to ensure that their drug has a significant net-benefit. Furthermore, the Phase IV study for Aduhelm was not placebo-controlled, which makes the analysis of its data more ambiguous.
How Could Aduhelm Potentially Cause Death?
Biogen's Aduhelm trials had not only prompted skepticism of its efficacy and research methods, but it also raised questions regarding the potential harm caused to Alzheimer's patients. Among the observed side effects in Phases I-III, the most common include amyloid-related imaging abnormalities (ARIAs)—also known as cerebral edemas and microhemorrhages, which can be harmful to patients with Alzheimer's disease.
According to the FDA Adverse Event Reporting System (FAERS), "the fatal case came from a 75-year-old female in Canada after she was diagnosed with brain swelling and bleeding, or amyloid-related imaging abnormality (ARIA)." Because its previous studies had shown that an increase in ARIAs is potentially linked to Aduhelm, this may be evidence of causality between Aduhelm and Alzheimer patient deaths.
How Should I Make Sense of This as a Consumer?
Coupled with the recent vote by the European Union to reject the drug entering its pharmaceutical market, and Biogen reporting that it fell almost 98% below analyst sales projections for 2021 Q3, the future of Aduhelm remains uncertain.
As a consumer or patient, it is best to err on the side of caution due to the ongoing developments of this drug. Additionally, if you or a loved one have suffered adverse effects of the Aduhelm (Aducanumab) drug, please be advised that you have legal rights to pursue a claim. At Rheingold, Giuffra, Ruffo & Plotkin LLP, we specialize in medical malpractice, mass tort, personal injury, and product liability cases. We aggressively represent our clients and have recovered billions from companies similar to Biogen. Please contact our office for a free, confidential evaluation of a potential claim. Please call (888) 260 – 0473 to speak with us directly and receive a free consultation.
Aug 20 Aduhelm® Alzheimer's Disease Drug: The FDA Approval Backlash
A recently approved Biogen Alzheimer's drug, Aduhelm® (Aducanumab), raises questions about the ethics of a laissez-faire, ...

redpajama_set_name: RedPajamaCommonCrawl


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Nationalist anti-Islam party PVV won't be in next Dutch cabinet: ING Analyst
Jan 11 '17 09:10
PoliticsTop Stories
Anti-Islam nationalist party PVV will not be in the next Dutch government after the elections in March of this year, according to ING economists Martin van Vliet and Dimitry Flemming. In a report titled Much ado about nothing... probably, they list several reasons why they believe Geert Wilders and his PVV will not cause political earthquakes after the elections, Business Insider Nederland reports.
Controversial TTIP trade deal good for Netherlands say economists
Jun 10 '16 11:53
The controversial trade agreement between Europe and the United States TTIP will be good for the Dutch economy, according to 71 percent of economists panel Me Judice in a Nieuwsuur survey
PM Rutte: Return Netherlands to the Golden Age
Aug 24 '15 12:15
Prime Minister Mark Rutte wants the Netherlands to return to the atmosphere of the Golden Age. According to him, there are many pillars on which the enterprising Netherlands can build on.
Economy growing faster, but still slow: Rabobank
The Ducth economy will grow by 1.5 percent in 2015, twice as fast as in 2014. There is however no reason for exuberant optimism, say economist of Rabobank in their Vision of 2015.
New push for transparency in economic analysis
Economic analysts from ING and ABN Amro have differing predictions on the state of construction in The Netherlands this year. ABN Amro says that there will be a 1 percent decrease in production this year, whereas ING thinks there will be 3.5 percent growth. Analysts from the Economic Institute for Construction now want to know how these numbers are drawn up, BNR reports.
Housing recovery on horizon: Rabobank
The Rabobank is counting on it that housing prices will rise this year. The bank's economic office is saying that sale homes will on average become between 0 and 1 percent more expensive this year, and between 1 and 3 percent more expensive next year, according to a report from the biggest mortgage office of the Netherlands.
Price of coffee set to rise
May 1 '14 11:39
Due to the intensely dry weather in the United States and Brazil, the price of coffee beans, among other goods, is skyrocketing.


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Semi-truck destroys Historic Bridge in Indiana Town
Photo taken by Tony Dillon in 2010
1880 Bridge built by Cleveland Bridge and Iron Company destroyed by semi-truck.
PAOLI, INDIANA- Normally on Christmas Day, Santa Claus brings good tidings and gifts to all the families and their children. This also includes any support for preserving historic bridges.
Unfortunately, for the community of Paoli in southern Indiana, Santa Claus was not kind to them at all, as the small community lost a treasured historic landmark that had once spanned Lick Creek on Gospel Street.
On Christmas Day in the afternoon, a semi-truck driver, ignoring the weight limit got herself wedged inside an iron through truss bridge, causing the semi-truck and the structure to drop in the water in a matter of seconds. Fortunately, she and a passenger were not injured in the wreck, but beams had to be cut apart to allow crews to free the truck and get it out of the water. In addition, 35 tons of bottled water had to be removed from the truck before it could be pulled out of the water. The weight limit was six tons at the time of the accident. Charges of reckless driving and damage to property are expected, according to multiple sources. This is the second time in two weeks that an accident involving a truckload of beverages has occurred. An accident on the German Autobahn near Magdeburg in Germany two weeks ago resulted in a trucker losing his entire truckload of beer onto the highway, shutting it down for hours while crews cleared crates and broken glass from the highway.
The bridge sustained severe damage to the southern end, where the truck struck the top chord and is currently leaning to one side towards a pedestrian located next to it. That crossing was closed off temporarily for safety reasons. While traffic has been rerouted to the 1st Street Bridge to the west, chances are likely that the bridge will need to be rebuilt, which could take months to complete. Whether it will mimic the crossing brought down by the truck remains open as of right now.
The Gospel Street Bridge was an example of an iron truss bridge built by the Cleveland Bridge and Iron Company in neighboring Ohio, having been constructed in 1880. Only a handful exist today, mostly in Indiana and Ohio. The bridge was an eight-panel iron through truss bridge with Town Lattice bracings. The builder's plaque was on each portal of the bridge. The length was 93 feet, making it one of the shortest crossings in Orange County. Also unique is a bowstring arch bridge, built in the 1930s, that is located right next to the bridge, used for pedestrian traffic only. That bridge is the subject of a Mystery Bridge article shown in the next article…..
By Bridgehunter's Chroniclesin News 27. December 2015 464 Words6 Comments


The 40-mile (M) route goes north to Fairfax, through Buck Hollow into Fairfield, returning via St. Albans. The longer loop (58 M/S) continues into Sheldon. There are potential food stops in St. Albans, Georgia and Fairfax.


text:
President Mahama unveils ONUADO health outreach In Sekondi
President John Dramani Mahama has launched the Ministry of Health's National Medical Outreach Services dubbed "ONUADO" which means "love your neighbor" at the Sekondi Naval Base.
The services will cover communities in forty-three districts under the phase one.
They include six districts each in the Western and Volta Regions, three each in the Eastern, Greater Accra, Brong Ahafo and Ashanti, five in the Northern and four each in the Upper West and Upper East Regions.
President Mahama also inaugurated eight vehicles to be used for the programme.
He said government has so far spent one billion dollars on all health facilities. President Mahama noted that the Medical Outreach Services will cater for the unserved areas of the country.
Meanwhile, the Minister of Health, Alex Segbefia says the launch of the Medical Outreach Services fall in line with government's decentralisation process.
Source: GBC
NextMOH takes steps to achieve MGD 5 in 2015
Most cancer cases 'caused by lifestyle, environment – not bad luck'
Cocoa Helps Kidney Patients Stave Off Heart Failure
Post-Ebola: how can the WHO get back its teeth?


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Fatal Crash Tillamook River Road near Burton Rd, Tillamook Sunday March 29th
Editor March 31, 2020 Crime, Press Release, Public Safety, Tillamook County Sheriff
On March 29, 2020 at about 4:46pm Tillamook County Sheriff's Office and other emergency personnel responded to Tillamook River Rd near Burton Rd. in reference to a single vehicle crash.
Preliminary investigation revealed a 2008 Chevy 4 door Sedan, driven by Christian Chavez, age 30, from Tillamook, was northbound on Tillamook River Rd, reportedly at a high rate of speed. The vehicle lost control on a sharp corner and crashed. Inside the vehicle was a passenger, Pedro Garcia Vargas, age 25, from Tillamook. C. Chavez reportedly exited the vehicle and made his way to a nearby residence where he requested assistance.
Pedro Garcia Vargas was pronounced deceased at the scene by emergency personnel. C. Chavez was transported to Tillamook Adventist Hospital for evaluation. Based on his statements and voluntary testing, C. Chavez was found to be impaired at the time of the crash. Upon his release from the hospital, C. Chavez was arrested for an outstanding warrant and for Manslaughter II and housed at the Tillamook County Jail.
The Tillamook County Sheriff's office was assisted by Oregon State Police, Tillamook Fire
District, and Tillamook Adventist Ambulance.
From Adventist Health Tillamook: Prepared, Ready, Taking Care of Your Health
Rainbow Art Brings Hope to Our World – Make Rainbow Art, Win Art Supplies


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Posted at 12:59 pm on 24th September, 2020
GCSE Results 2020
After a turbulent period for our Year 11 students and their families, we were delighted to celebrate with the Class of 2020 on GCSE results day. Once again, Wellacre boys did themselves and their school proud.
The results awarded this year were not just about the final grade, but a massive reflection the hard work, commitment and dedication the class of 2020 had shown over the last 5 years. Throughout their time at Wellacre they have spent their days pushing themselves further, motivating themselves and challenging themselves to be the best they could be.
Our students have been a credit to Wellacre and have contributed so much to our school community during their time with us. We wish them all the very best for their future endeavours and hope that we see them back soon, inspiring the next generation of boys.
Wellacre Principal Mrs Wicks said;
"I'm so proud of the Class of 2020. It has been a privilege to watch them grow and develop into hard working, polite, kind and resilient young men.
"There are many more opportunities for them to explore and certainly more challenges ahead, but the skills they have acquired will ensure they are ready for them. My message to the boys is "Be proud of who you are and all that you have to offer the world. Always believe in yourself, take pride in who you are and how far you have come. You were born to be successful. Go out and conquer the world!"
There were many notable individual successes including the following students:
Twins Jack and Thomas matched each others' success with fantastic results enabling them to move onwards and up.
Jack GCSE awards included grade 8s in Maths, Biology, Chemistry and Computer Science, a grade 7 in Physics and a Distinction* in Design in the Built Environment, alongside Thomas whose results included grade 9 in Computer Science, a grade 8 in Biology, grade 7s in English Language, Maths, Chemistry and Physics, and a Distinction* in Design in the Built Environment. These results see the brothers carry on their learning journey together as they join Urmston Grammar School to study Computing, Physics and Maths A Levels side-by-side!
Jack said: "It's been an emotional rollercoaster but it's all worked out! I'm so glad I've got everything I needed, especially the grade 8 in Maths."
Thomas added: "I was really pleased about the grade 9 in Computing and grade 7 in Maths. I'm excited about moving on to Urmston Grammar School."
Brothers Jack and Joseph also celebrated an outstanding pair of results between them! Jack's first class results included grade 9s in English Language, Maths, Combined Science, French and Geography, a grade 8 in English Literature and a Distinction* in Sport and he has moved on to Stretford Grammar to study A Levels in Biology, Maths and Physics.
Joseph's equally fantastic results included grade 8s in English Language and Literature, grade 7s in Science and Geography and a Distinction* in Sport. He has joined Eccles College to take up A Levels in Psychology and Criminology, and BTEC Sport.
Leo had his sights set on Computer Science, Physics, Maths and Psychology A Levels at Urmston Grammar School and his results ensured his success. His results included grade 9s in Computer Science, Physics and Maths, grade 8s in Biology and Chemistry and a Distinction* in Music.
He said: "I got everything I needed and more, with three grade 9s. I'm really excited to start college!"


In France, race is widely considered to be an invalid category of identification. In 2013, the National Assembly voted to remove all traces of the word from French legislation. A strict set of laws forbids the collection of census or data based on race, ethnicity or religion. Equality, as illustrated by the Republic's color-blind stance, denies identity-claim made on racial grounds. Yet, despite this egalitarian stance, the national conception of citizenship has produced, and continues to produce, religious and ethnic identities.


Two hours south of Christchurch (and a similar distance north of Dunedin) is Canterbury's largest regional hub, Timaru. As a coastal town, Timaru is set amongst an agricultural hinterland, and serving as centre of a region which includes Geraldine, Waimate, Temuka and Pleasant Point as satellite towns. Timaru is built on the hills created by lava flow from the extinct Mount Horrible, resulting in some steep and winding streets, and providing the distinct 'bluestone' rock from which many of the town's buildings are constructed.
The first European settlers arrived here in the 1830s and built a whaling station. One of the first supply ships, the Caroline, gave its name to the popular seaside resort of Caroline Bay, with its boardwalks, beaches and playgrounds, just to the north of the town. But the continuous loss of several ships coming and going from the natural port (due to the hazardous waters), led to an artificial port being built in the 1880s, and the area around Caroline Bay, where much of the sand being washed down the coastline, ended up, is still growing today.
Timaru is the country's second largest fishing port, and also acts as a major freight corridor, thanks to the South Island Main Trunk Railway, which passes through here, but with the cancellation of passenger services in 2002, it was to the airport that many people found themselves landing, which offers regular hops to Wellington.
Stafford Street is where the main CBD of Timaru lies, with plenty of shops, bars and restaurants, and some lovely old buildings reflecting the town's Victorian roots. The main attraction for visitor to Timaru is the South Canterbury Museum, which details the area's geological roots, with plenty of fossils, old mining artefacts, and the impressive EP Sealy Natural History Collection. The museum also presents the life story of local hero, Richard Pearse, an early 20th century inventor and adventurer, who many think was the first person to take to the skies in a heavier-than-air machine, many months before the Wright brothers, in 1903.
Creative types might want to check out the Aigantighe, the South Island's third largest art museum, which holds an impressive art collection, some exhibits dating from the 16th century. Explore the sculpture garden, and enjoy the quaintness of the 1908 homestead in which the gallery is housed.
On Sheffield Street, you'll find the DB Mainland Brewery, which conducts regular tours and tastings, and if you're lucky enough to be here in January, you can take part in the Caroline Bay Carnival, a cornucopia of parades, live music, entertainment and frivolity in Caroline Bay Park.
For sports, head to Aorangi Park for athletics action, or one of the town's two major swimming pools for something a little more leisurely, while surfers should make a beeline for Patiti Point or Jack's Point.
Explore Timaru Botanic Gardens and the Trevor Griffiths Rose Garden (Timaru has its own rose, the "Trumpeter", named after Louis Armstrong), or just wander the streets and pick out the splendid examples of Victorian and Edwardian architecture. For a really laid back day, head to The Piazza, high above Caroline Bay, and relax in this newly-developed complex with its cafes and bars, all with amazing views across the ocean and to the mountains beyond.


A Polish pair, who was just returning from helping out refugees in Serbia (or was it Greece?). He had a fanastic conversation and they were also hosting on CS. Offered me a place to stay as it was already dark at that point. but I wanted to get as far north on the autostrada as possible, so I declined and chose to get off at a gas station instead. The girl studied in China, which I was completely fascinated by.
After a day full of awesome rides, I was ready to get to Gdansk that night (which is crazy considering I'd started hitching after work, so at around 5pm). Asked pretty much like two people and the third said yes (also a bit hesitantly). It was a family traveling in two cars and towing another one. Didn't talk much, but were driving all the way to Gdansk! Nevertheless, their car broke down and so we pulled over to a rest area where they tried to fix it. Since I was quite close to Gdansk and was headed for Russian anyway, I decided to call it a day and pitch my tent at the rest area, which had a beautiful grassy patch and toilets. They did eventually manage to fix the car, but I was almost asleep at that point. Awesome hitching day, I never thought I'd have gotten this far at 5pm. Gotta love Poland!


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Displaying 1 to 11 of 11 results for scleroderma
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Allan Gelber Lab
The Allan Gelber Lab conducts research on the clinical epidemiology of rheumatic disorders. Our recent studies have explored topics that include the predicting factors of prevalent and incident gout; cardiovascular disease burden and risk in patients with rheumatoid arthritis; autoantibodies in both primary and secondary SjogrenÕs syndrome; and predictors of outcomes in patients with scleroderma. In addition, we have a long-standing interest in the ways in which racial differences affect disease manifestations in relation to rheumatic disorders.
Research Areas: rheumatology, gout, Sjogren's syndrome, scleroderma, race, health disparities, rheumatoid arthritis
Allan Gelber, M.D., M.P.H., Ph.D.
Ami Shah Lab
Researchers in the Ami Shah Lab study scleroderma and Raynaud's phenomenon. We examine the relationship between cancer and scleroderma, with a focus on how and if cancer causes scleroderma to develop in some patients. We are currently conducting clinical research to study ways to detect cardiopulmonary complications in patients with scleroderma, biological and imaging markers of Raynaud's phenomenon, and drugs that improve aspects of scleroderma.
Research Areas: Raynaud's phenomenon, cancer, scleroderma, drugs, cardiovascular diseases
Lab Website
Ami Shah, M.D.
Antony Rosen Lab
Research in the Antony Rosen Lab investigates the mechanisms shared by the autoimmune rheumatic diseases such as lupus, myositis, rheumatoid arthritis, scleroderma and SjogrenÕs syndrome. We focus on the fate of autoantigens in target cells during various circumstances, such as viral infection, relevant immune effector pathways and exposure to ultraviolet radiation. Our recent research has sought to define the traits of autoantibodies that enable them to induce cellular or molecular dysfunction. We also work to better understand the mechanisms that form the striking connections between autoimmunity and cancer.
Research Areas: myositis, lupus, rheumatology, Sjogren's syndrome, scleroderma, autoimmune rheumatic diseases, rheumatoid arthritis
Antony Rosen, M.B.Ch.B., M.S.
Fredrick Wigley Lab
The Frederick Wigley Lab is interested in the signs, symptoms and causes of scleroderma. We are testing new treatments for RaynaudÕs phenomenon and scleroderma. Understanding the treatment approach to Raynaud's phenomenon and associated ischemia and how to prevent digital ulcers is important for clinicians caring for these patients. Work in our lab has provided guidance in the management of Raynaud's phenomenon and digital ischemic ulcers, including options for the practical pharmacologic and nonpharmacologic interventions.
Research Areas: Raynaud's phenomenon, rheumatology, scleroderma, autoimmune diseases, systemic sclerosis, ischemic ulcers
Fredrick Wigley, M.D.
Laura Hummers Lab
The Laura Hummers Lab participates in a number of clinical trials and clinical investigations at the Scleroderma Center at Johns Hopkins. We have a particular interest in the predictors of outcomes in scleroderma. We've established a prospective cohort of 300 scleroderma patients to identify incident vascular outcomes in the hopes of identifying new biomarkers for disease development and progression.
Research Areas: rheumatology, biomarkers, scleroderma
Laura Hummers, M.D.
Livia Casciola-Rosen Lab
Work in the Livia Casciola-Rosen Lab explores the shared mechanisms present in autoimmune rheumatic diseases, specifically scleroderma, Sjogren's syndrome and myositis. We use disease-specific autoantibodies to identify the factors that cause the autoimmune response in such diseases. Our current research involves identifying the antigen targets of autoimmune diseases, investigating the autoantigens targeted in cancers associated with rheumatic diseases and finding unique clinical biomarkers, such as the anti-HMGCR antibody specificity.
Research Areas: autoantibodies, myositis, rheumatology, Sjogren's syndrome, scleroderma, autoimmune rheumatic diseases
Livia Casciola-Rosen, Ph.D.
Paul M. Hassoun Lab
The Paul M. Hassoun Lab leads research on the source and treatment of pulmonary arterial hypertension in scleroderma.
Research Areas: pulmonary arterial hypertension, scleroderma, hypertension, lung disease
Paul Hassoun, M.D.
Rachel Damico Lab
Work in the Rachel Damico Lab explores topics within the fields of vascular biology and pulmonary medicine, with a focus on acute lung injury and apoptosis in lung diseases. Our studies have included examining idiopathic and scleroderma-associated pulmonary arterial hypertension, vascular receptor autoantibodies, and the link between inflammation and the Warburg phenomenon in patients with pulmonary arterial hypertension. We have also researched the inhibitory factor of macrophage migration and its governing of endothelial cell sensitivity to LPS-induced apoptosis.
Research Areas: critical care medicine, acute lung injury, lung disease, vascular biology, apoptosis
Rachel Damico, M.D., Ph.D.
Robert Wise Lab
The Robert Wise Lab conducts clinical trials to study chronic obstructive lung diseases (COPD). We investigate inhaled corticosteroids in patients with mild to moderate COPD and the effectiveness of anti-inflammatories in allowing lung growth in mild to moderate asthmatic children. Our research includes exploring the efficacy of various treatments for asthmatic women who are pregnant and of lung-volume reduction surgery for emphysema patients. We also conduct studies of the clinical epidemiology, pathobiology and treatment of interstitial lung disease in patients with scleroderma.
Research Areas: critical care medicine, emphysema, scleroderma, pulmonary medicine, asthma, lung-volume reduction surgery, COPD
Robert Wise, M.D.
Stephen Mathai Lab
The Stephen Mathai Lab focuses its research on pulmonary medicine. We're particularly interested in scleroderma-associated pulmonary hypertension, pulmonary complications of connective tissue disease, idiopathic pulmonary fibrosis and pulmonary hypertension.
Research Areas: scleroderma, pulmonary medicine, hypertension, pulmonary fibrosis, connective tissue disease
Stephen Mathai, M.D., M.H.S.
Zsuzsanna McMahan Lab
The Zsuzsanna McMahan Lab conducts translational research that seeks to identify the novel antigens in scleroderma and to define the target tissue in this disease. We are conducting two active clinical research trials, including one that studies skin biopsy specimens as biomarkers of scleroderma and the response to mycophenolate mofetil (MMF or Cellcept). The other study is a gastrointestinal involvement registry that follows patients who are experiencing GERD, small bowel bacterial overgrowth, constipation, fecal incontinence and gastroparesis to see if there is improvement in symptoms after a change in treatment is implemented.
Research Areas: gastrointestinal system, rheumatology, biomarkers, scleroderma, antigens, mycophenolate mofetil
Zsuzsanna McMahan, M.D., M.H.S.


A Women's Guide To Changing A Tire | It's my life, you're just along for the ride!
Hazard lights are not only for your safety, but they're really cute whenever they're flashing, and can draw attention to you. Brittany Hornick and Rachael Acosta poke fun at female stereotypes in this sarcastic video which does ultimately show how to change a tire.
This entry was posted in HowTo, Humor, Interesting, tips. Bookmark the permalink.


Experts from Modern Cancer Hospital Guangzhou said that diet is very important for laryngeal cancer patients. Proper diet has positive effect to their bodies.
1. Diet for laryngeal cancer patients should be nutritious and digestible, and contain rich protein and vitamin. It should be diversified and maintain good favor, color and smell, so as to improve patients' appetite. It is better to be light food and avoid fatty food. If patients lose appetite, appetizer can be added to the diet to improve their appetite. It is recommended to eat less in a meal but more meals in a day.
2. Light food and foods that can prevent ulcer, clear heat and toxic substance, spinach for example.
3. Foods aiming at the symptoms: for patients who have hoarseness: a carrot, pear, ginkgo and plum, etc.; for patients who have difficulty in swallowing: almond, peach seed and lily, etc.; for patients who have hemoptysis: lotus powder, day lily, etc.
4. Foods effective in resisting laryngeal cancer: almond, eggplant, etc.
5. Dietary restrictions: avoid smoking, drinking, spicy food. When there is complicating infection, do not eat meat that is of pathogenic heat,mutton for example. It is recommended for patients to eat and arrange their diet plan according to their personal toleration. It is encouraged for them to eat more when they have good appetite and do not compel them to eat those they do not like, so as to avoid nausea or vomiting.
Laryngeal cancer patients should pay attention to supplement of nutrient and scientifically make a diet plan. As fact has proved that nutrient is very important for patients' treatment and rehabilitation. It can help patients recover from surgery more quickly and enhance patients' toleration to radiotherapy and chemotherapy, as well as improve their immunity and prevent complications like infection.
1. Diet after surgery: foods good for patients after laryngeal cancer surgery: almond juice, sorb juice, sugar cane juice, pineapple juice, fig juice, jujube juice, kiwi fruit juice.
2. Diet during radiotherapy: fresh vegetable and fruit, mushroom, tofu, spinage, etc.
3. Diet during chemotherapy: turtle, carp, tremella, shiitake, edible bird's nest, sunflower, sorb, ginkgo, etc. which are helpful in .
Experts from Modern Cancer Hospital Guangzhou point out laryngeal cancer patients should not over rely on above three eating methods. Instead, they should overcome choking problem through swallowing practice. For some patients who fail to overcome the problem through swallowing practice, surgery will be needed. However, it may result in loss of language function. Moreover, in daily life and during treatment procedure, patients should pay attention to the balance of nutrient, so as to improve their immunity and lay the foundation for their rehabilitation.


Adam and Dr. Drew open the show discussing some recent frustrations Adam has been having with his good friend Ray over his involvement in Adam's impending Spike TV show. This leads into a wider conversation as to how people who are severely tuned out are seemingly incapable of pulling away from their bad habits. As the show winds down they turn to the phones and the conversation on habits continues to evolve.
This entry was posted in Podcast on March 5, 2017 by Chris Laxamana.