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The State of the Union: Three Women
By Amy Davidson Sorkin
There were three men in front of the room for the State of the Union address on Tuesday night—President Obama, Vice-President Joseph Biden, and Speaker of the House John Boehner—and men made up the great majority of the chamber. The imbalance is not as far off as it was a half a century ago, but the numbers are still lopsided. (Seventeen Senators are women, and seventy-three Representatives, which also works out to just about seventeen per cent.) One of those congresswomen was about to depart for good, or at least for a long while: Gabrielle Giffords, of Arizona, who announced over the weekend that she was resigning. She had come incredibly far for this goodbye; after she was shot and six others were killed by a gunman a year ago, Obama, in one of the better speeches of his Presidency, electrified a crowd by telling them that, against what were then all expectations, "Gabbie opened her eyes."
There was no moment like that in this address, although the sight of Obama embracing Giffords conveyed genuine joy, and that of an Arizona Republican, Jeff Flake, helping her stand up to cheer for him, real friendship. Perhaps there couldn't be; a State of the Union is more of a ritual. And yet Giffords and other women at the speech, both legislators and guests, provided some of its most arresting, and challenging, moments.
Sometimes a person can become a symbol without ever being seen. "Warren Buffett's secretary" is a phrase that sounds like it was made up by an economics-textbook writer, to illustrate a point—the tax-policy version of "Shakespeare's sister." But Debbie Bosanek was always a real person. Buffett didn't make her up; nor did he invent the reason he began talking about her. As he wrote in an Op-Ed for the Times last year (with the evocative title "Stop Coddling the Super Rich"), "what I paid was only 17.4 percent of my taxable income—and that's actually a lower percentage than was paid by any of the other twenty people in our office." Last night Obama said,
Right now … a quarter of all millionaires pay lower tax rates than millions of middle-class households. Right now, Warren Buffett pays a lower tax rate than his secretary.
Bosanek was sitting in the First Lady's box, which meant that the camera had somewhere to look other than at John Boehner (skeptical, with a polka-dot tie) or Joe Biden (fidgeting, with a striped tie). Bosanek, in a dark red jacket that matched the frames of her glasses, tilted her head and gently nodded. She also—and the White House, when it issued the invitation, probably had a pretty good sense of this—pays a greater share of her income in taxes than Mitt Romney does. (In 2010, Romney paid 13.9 per cent—less than Buffett.) She told the Washington Post that she follows Buffett's lead on tax policies, but didn't want to get into her political views. ("I never discuss that.") She did say that, in being at the State of the Union, "I feel like I'm representing secretaries everywhere." Newt Gingrich, in a speech a few hours before the State of the Union, spoke mockingly about somewhere called "Planet Obama." (All that talk of Mars in Monday night's debate may have got to him.) But Bosanek lives in a place that many of us would simply call the real world.
Other guests in the First Lady's box were members of the military or military spouses or, in one case, both. (That guest was Sergeant Ashleigh Berg; she has served two tours in Iraq, and her husband, Sergeant Matthew Berg, is on his third tour in Afghanistan.) Their lives told a series of stories: that soldiers, like secretaries, are not abstractions; that wars are never distant things that can just be fought in a faraway place and left there; and that the military as much as the civilian sphere is a place where our values can be embraced and realized, rather than abandoned. As he closed his speech, Obama said,
When you put on that uniform, it doesn't matter if you're black or white; Asian, Latino, Native American; conservative, liberal; rich, poor; gay, straight. When you're marching into battle, you look out for the person next to you, or the mission fails. When you're in the thick of the fight, you rise or fall as one unit, serving one nation, leaving no one behind.
Obama, who, three years ago, invited all of the surviving Tuskegee Airmen to his inauguration, knows that the uniform has not always been quite such a magic cloak, even as the military can and has been a transformative civic classroom. (Last week, Obama also hosted a screening of "Red Tails," George Lucas's new movie about the Tuskegee Airmen, which deals with the discrimination they faced as black pilots in the Second World War.) We are getting better, and sometimes soldiers get there first. One particular woman sitting with Michelle Obama helped keep the President's peroration from sinking too far into metaphor: Colonel Ginger Wallace. She has been in the Air Force for twenty years. She is a lesbian whose partner, thanks to the repeal of Don't Ask Don't Tell, was able to take part in her promotion ceremony in December.
It is a moral and political victory that Colonel Wallace and other members of the military can now serve their country without having to lie; for years we had been asking service members to be brave, and then giving them, needlessly, reasons to be afraid—exposed to battle, wary of exposure. Colonel Wallace could not be more visible now. It would be blind to say she is safe—she is heading to Afghanistan soon—but at least she does not need to hide. And yet her story also suggests some uncompleted work: when can her partner have the option of being a military spouse? It is one thing to take part in a promotion ceremony; it is another to have the legal protections and recognition that comes with marriage. Who needs that more than soldiers, who too often may need to know that someone they love has unquestioned right to a hospital room, or to be the one who gets bad news? Who deserves it more?
President Obama tried to make the story of the assault that killed Osama bin Laden a metaphor for the way the members of a society depend on each other:
You can't charge up those stairs, into darkness and danger, unless you know that there's somebody behind you, watching your back. So it is with America…. This nation is great because we worked as a team. This nation is great because we get each other's backs.
Those words echo a theme that Elizabeth Warren, a former Harvard professor who helped conceive of the Consumer Financial Protection Bureau, has repeated in her speeches: that no one succeeds entirely on his or her own, detached from our web of mutual obligation. Warren is running for the Senate in Massachusetts. Perhaps, for next year's State of the Union, she will be another woman in the room.
Photograph by Saul Loeb-Pool/Getty Images.
Amy Davidson Sorkin has been a staff writer at The New Yorker since 2014.
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Located 13 km from San Jose StartUp Fever offers accommodation in Sunnyvale. The holiday home is fitted with air conditioning and free WiFi. Free private parking is available on site.
The kitchen has a dishwasher an oven and a microwave as well as a coffee machine.
Santa Cruz is 47 km from StartUp Fever while Half Moon Bay is 37 km away. The nearest airport is Mineta San Jose International Airport 9 km from StartUp Fever.


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Naturally DIY
Uutěrky
Návsí u Jablunkova
Martin KrkošekPavla Krkošová Byrtusová
UutěrkyPerpedes Grants
They form a pair. Martin Krkošek and Pavla Krkošová Byrtusová, partners both in their personal and professional lives, live in Návsí u Jablunkova, a stone's throw away from the Slovakian border, just between Třinec and Žilina.
Návsí is spread out along the main road, and cannot boast anything akin to a city center, but is instead surrounded by deep forest on all sides. In the workshop Uutěrky, everything centers on the home-made screen prints which Krkošek and Byrtusová have been making for the last six years.
"We are a self-supported screen printing workshop. We try to do things at low cost, but with that much more devotion. We are sometimes pleased with the flaws which occur, as they are really an integral part of the whole process. We do not like to call our customers 'clients,' and are glad to make friends with them, which usually happens naturally anyway," says Krkošek.
Apart from screen printing, Krkošek also devotes his time to book illustrations, graphic design, animation and teaching. Byrtusová paints, draws, photographs, and writes texts for various publications. They are both inspired by work in the garden, working with children, the art world, local lore and, of course, their beautiful surroundings.
Krkošek says that their clients (a.k.a. _friends)) come to them on their own: "We usually have similar people find us, people with whom we click – like bands making an LP. They sometimes do some of the work themselves, and I help them print it, cut it or glue it. The product is, from the very outset, all done in a DIY fashion." For example, this is how they collaborate with the Analog Freaks record label. Another long-term and important partner for Uutěrky, the Slovakian Stanica, is a vibrant cultural center situated at the Žilina-Záriečie train station. That is also where Byrtusová and Krkošek have their screen printing workshop at the moment, and Krkošek regularly goes there to teach creative courses. For these he makes various worksheets and teaching aids which are mini art pieces in themselves. In Slovakia, they also collaborate with the Periférny Centra, for example, a rural cultural organization located in Dúbravice u Banské Bystrice.
"If we had to sum it up, we work in services – that is screen printing, graphic works, illustration, book binding, photography and, let's say, pedagogy," says Krkošek, explaining the work of Uutěrky. Byrtusová adds: "We enjoy handcrafting and slow work in the workshop. At home, we have a garden, and everything takes place at a natural pace. We want to keep it that way, so we will always be able to put food on the table, but also keep enjoying the work."
Apart from providing services, the Uutěrky couple also work on their own projects, such as original publications (like Listování, Byrtusová's poetic visual essay which connects gardening and the inspiration gained from Martin Ryšavý's Siberian travelogue), collections (like KABINETbotanika, a colorful and diverse collection consisting of various contributions), poetry and nursery rhymes from around the region of Jablunkov (bojtky), and the newly published Pidiskicák. They also print on textiles, such as shirts, handkerchiefs and bags.
Sometimes people invite them to teach book binding, origami making and embroidery. At the moment, they would like to publish an encyclopedia which was originally intended for educational workshops at Žilina's Stanica. The various entries are take the form of comics, in which a cricket, a rat, and some salamanders discuss various types of art. The book will be called (Ne)všední den pana Stana, or (Mr. Stan's (Extra)Ordinary Day) and two years ago, they presented illustrations for the encyclopedia at an exhibition in Týn nad Vltavou.
They are now considering moving their workshop to Návsí, which is possible due to the friendly treatment they get from the local municipality who support them in various ways. Krkošek decorated the local elementary school with his illustrations, and Byrtusová has also photographed the local kindergarten children. They were recently commissioned to draft the design for the pedestrian underpass in Návsí.
Byrtusová laughs that they are like "some sort of decorating band," while Krkošek comments that the various collaborations have been going well because they "try to do things somehow naturally, and it seems to be working."
Lenka Dolanová
Uutěrky Website
Uutěrky FB
Stanica
Periferne Centra

redpajama_set_name: RedPajamaCommonCrawl


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La Grande Ville (titre original en bengali : মহানগর, ) est un film indien réalisé par Satyajit Ray, sorti en 1963.

Le film est également connu en français sous son titre d'exploitation initial et en DVD : La Grande Cité.

Synopsis
Calcutta. Subrata Mazumdar, modeste employé de banque à Calcutta, peine à subvenir aux besoins de sa famille, dont ses parents âgés qui partagent sa maison. Allant contre les règles établies, et afin d'améliorer le quotidien de toute la famille, sa femme Arati part en ville chercher du travail, à la réprobation de son beau-père, professeur à la retraite. Elle est embauchée dans une société de matériels ménagers et fait du porte à porte pour vendre des machines à coudre. Par sa personnalité et ses résultats, elle attire l'attention de son directeur qui envisage de lui donner d'autres responsabilités. Mais Subatra accepte mal cette situation, et il conduit Arati à accepter de signer une lettre de démission. Cependant, la banque qui l'emploie fait faillite. In extremis, il arrive à prévenir Arati de ne pas remettre sa lettre. Quelques semaines plus tard, une collègue anglo-indienne d'Arati est renvoyée avec comme motif absence pour maladie. Devant ce qui lui parait être une injustice, Arati se fâche avec son patron et finit par lui remettre sa démission. Touché par la droiture de sa femme, Subrata et celle-ci envisagent l'avenir avec confiance.

Fiche technique
 Titre français : La Grande Ville ou La Grande Cité
 Titre original : মহানগর, Mahanagar
 Réalisation : Satyajit Ray
 Scénario : Satyajit Ray, d'après une histoire originale de Narendranath Mitra
 Production : R.D. Bansal
 Musique : Satyajit Ray
 Photographie : Subrata Mitra
 Montage : Dulal Dutta
 Décors : Bansi Chandragupta
 Format : Noir et Blanc - 35 mm - Son : mono
 Durée : 131 minutes
 Langue : Bengali, Anglais
 Pays :
 Budget : USD
 Dates de sortie :
  :
  : juin 1964 au festival de Berlin

Distribution
 Anil Chatterjee : Subrata Mazumdar
 Madhabi Mukherjee : Arati Mazumder
 Jaya Bhaduri : Bani
 Haren Chatterjee : Priyogopal (Père de Subrata)
 Sefalika Devi : Sarojini (Mère de Subrata)
 Prasenjit Sarkar : Pintu
 Haradhan Bannerjee : Himangshu Mukherjee
 Vicky Redwood : Edith

Distinctions
 Ours d'argent au festival de Berlin en 1964

Notes et références

Liens externes

Film dramatique indien
Film indien sorti en 1963
Film réalisé par Satyajit Ray
Film tourné à Calcutta
Film en bengali
Film indien en noir et blanc

redpajama_set_name: RedPajamaWikipedia


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Passenger jumps out of plane taxiing at Phoenix airport
Dec. 4, 2021 2:12 PM PT
PHOENIX —
A passenger on an arriving Southwest Airlines flight taxiing at Phoenix's main airport opened a galley door, jumped out and ran to an airport fire station where he barricaded himself, authorities said Saturday.
The man's identity wasn't immediately released, and it wasn't immediately clear why he jumped from Flight 4236 after it's arrival at Sky Harbor International Airport from Colorado Springs, Colorado, at about 8 a.m. Saturday.
After the man "exited the aircraft," the aircraft's captain notified the control tower so local authorities could respond to the situation, Southwest spokesperson Dan Landson said in an email. The plane with its crew and remaining passengers then went to its designated gate, Landson said.
Meanwhile, the 30-year-old man entered the fire station, walked into a dorm room and locked himself inside, Fire Capt. Todd Keller, a Phoenix Fire Department spokesperson, said in an email.
After few minutes, firefighters were able to get the man to unlock the door, and he was then evaluated, treated for a lower leg injury and transported to a hospital, Keller said.
The Phoenix Police Department said in an email it was investigating the incident and provided no additional information on the incident, including the man's status.
The incident did not delay airport operations, Sky Harbor spokesperson Julie Rodriguez said.
A Federal Aviation Administration spokesperson referred an inquiry to local authorities.
Top headlines by email, weekday mornings
Judge refuses to toss excessive force claims in man's death
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Russian President Vladimir Putin has hosted his Iranian counterpart, hailing their the two countries' cooperation on international issues, including the Syrian crisis
Psychiatrist on Norway mass killer: 'You cannot trust him'
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Anna Sorokin, inspiration for Netflix series 'Inventing Anna,' speaks about deportation fight
Published: Oct. 09, 2022, 1:00 p.m.
Anna Sorokin sits at the defense table in New York State Supreme Court, in New York, Wednesday, March 27, 2019. Sorokin, who claimed to be a German heiress, is on trial on grand larceny and theft of services charges. (AP Photo/Richard Drew)AP
Convicted swindler Anna Sorokin spoke to The New York Times about how important it is to her to remain in New York despite risks of deportation.
Sorokin, 31, was released Saturday from U.S immigration custody to house arrest. She told the Times she would feel like she was "running from something" if she were to let herself be deported to Germany.
"Letting them deport me would have been like a sign of capitulation — confirmation of this perception of me as this shallow person who only cares about obscene wealth, and that's just not the reality," Sorokin told the Times.
Last week, an immigration judge cleared the way for Sorokin to be released to home confinement while the deportation fight plays out. Now, she is wearing an ankle monitor after posting a $10,000 bond.
Sorokin for years used the name Anna Delvey to pass herself off as the wealthy daughter of a German diplomat, and lied about having a $67 million (68 million euros) bankroll overseas to create the impression that she could cover her debts, prosecutors said.
Her case became the basis for the Netflix series "Inventing Anna," released this year.
After serving three years in prison for conning $275,000 from banks, hotels and rich New Yorkers to finance her luxurious lifestyle, Sorokin was detained by immigration authorities last year who argued she had overstayed her visa and must return to Germany, where she is a citizen.
When asked about what she plans to do now, Sorokin told the Times she's working on her own podcast, which hasn't come to fruition yet, and that she wants to work on criminal justice reform to highlight the struggles of other girls.
Sorokin also spoke about how much she has learned while being in jail, and how it's impossible "to have been through what I've been through without changing."


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Christo, Famed Installation Artist, Dead at 84
Christo Vladimirov Javacheff, known as Christo, worked for decades with his wife and artistic partner, Jeanne-Claude Denat de Guillebon, to create massive installations around the world.
Robert Smithson's Spiral Jetty Turns 50
In the decades since its completion in 1970, Robert Smithson's massive work has become the most famous work of Land Art in the world.
Collecting Experiential Art: Capturing the Ephemeral
How artists, collectors, curators and museums value memory.
The Art History Babes Talk Robert Smithson's Spiral Jetty
Corrie & Nat discuss Robert Smithson's 1970 work of land art, Spiral Jetty. AKA Corrie gets weepy about a bunch of rocks in Utah. Plus a chat about the Met Gala. Originally Released May 17th, 2018
Andy Goldsworthy's "Watershed" Moment in New England
Andy Goldsworthy is a much-in-demand international figure known for creating ephemeral earthworks documented in meticulous photographs, and now New England has one of their own.
Body Art Then and Now in "a body measured against the earth"
The ecofeminist visions of artist Ana Mendieta and writer Rebecca Solnit guide this exhibition of works concerned with how the body relates to the earth. Drawn primarily from the Museum of…


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Current Progress of Gene Sequencing
Sequencing Progress: Pilot Phase
Sequencing Progress: Phase 1
Assembled bat genomes available to the public
Bat1K is currently in phase 1, please see the members area for detailed progress status. To date, there are 6 reference quality genomes released by Bat1k, alongside 15 prior bat genomes that have been made available to the public, as listed below:
1 Hipposideridae Hipposideros armiger Great Leaf-nosed Bat N India, Nepal, Burma, S & SE China, Vietnam, Laos, Cambodia, Thailand, Malay Peninsula, Taiwan. Dong et al., (2016) ~2.18 Gb
2 Megadermatidae Megaderma lyra Greater False Vampire Bat Afghanistan to S China, Burma, Thailand, Cambodia, Laos, Vietnam; south to Sri Lanka & W Malaysia; Bangladesh. Parker et al., (2013) ~1.8 Gb
3 Miniopterinae Miniopterus natalensis Natal Long-fingered Bat Sudan & SW Arabia to South Africa. Eckalbar et al., (2016) ~1.8 Gb
4 Mormoopidae Pteronotus parnellii Common Mustached Bat Peru, Bolivia, Brazil, Guianas, & Venezuela to S Sonora & S Tamaulipas (Mexico); Cuba; Jamaica; Puerto Rico; Hispaniola; St. Vincent; Trinidad & Tobago; Margarita Isl (Venezuela); La Gonave Isl (Haiti). Parker et al., (2013) ~2 Gb
5 Pteropodidae Eidolon helvum African Straw-coloured Fruit Bat Mauritania, Senegal, & Gambia to Ethiopia to South Africa; SW Arabia & Oman; isls in the Gulf of Guinea & off E Africa. Parker et al., (2013) ~1.9 Gb
6 Pteropodidae Pteropus alecto Black Flying Fox Sulawesi, Saleyer Isl, Lombok, Bawean Isl, Kangean Isls, Sumba Isl, & Savu Isl (Indonesia); N & E Australia; S New Guinea. Zhang et al., (2013) ~2 Gb
7 Pteropodidae Pteropus vampyrus Large Flying Fox Vietnam, Burma, Malay Peninsula, Borneo, Philippines, Sumatra, Java, & Lesser Sunda Isls, adjacent small isls including Anak Krakatau. http://www.ncbi.nlm.nih.gov/assembly/GCA_000151845.2#/st http://www.ncbi.nlm.nih.gov/genome/genomes/757? ~2.1 Gb
8 Rhinolophidae Rhinolophus ferrumequinum Greater Horseshoe Bat Algeria, Morocco, & Tunisia; S Europe from Portugal to Greece & north to S England, the Netherl&s, S Germany, Austria, Czech Republic, Slovakia, & Bulgaria; Turkey, Cyprus, Georgia, & Azerbaijan; Urkrain, Crimea, & Caucacus regions; the Mediterranean coas Parker et al., (2013) ~1.95 Gb
9 Rhinolophidae Rhinolophus sinicus Chinese Rufous Horseshoe Bat S China, Nepal, N India, Vietnam. Dong et al., (2016) 2.07 Gb
10 Vespertilionidae Eptesicus fuscus Big Brown Bat S Canada to Colombia & N Brazil; Greater Antilles; Bahamas; Dominica & Barbados (Lesser Antilles); Alaska. http://software.broadinstitute.org/allpaths-lg/blog/?p=606 ~2 Gb
11 Vespertilionidae Myotis brandtii Brandt's Myotis Britain south to Italy, Greece, & Bulgaria; east to Kazakhstan & Mongolia, E Siberia including Sakhalin Isls, Kamchatka Peninsula & Kurile Isls; Ussuri region (Russia); Korea. Seim et al., (2013) ~2 Gb
12 Vespertilionidae Myotis davidii David's Myotis N. China Zhang et al., (2013) ~2 Gb
13 Vespertilionidae Myotis lucifugus Little Brown Myotis Alaska (USA) to Labrador & Newfoundland (Canada), south to S California, N Arizona, N New Mexico (USA). https://www.broadinstitute.org/scientific-community/science/projects/mammals-models/brown-bat/little-brown-bat-genome-project MyoLuc 2.0, released July 2010 ~2 Gb
14 Phyllostomidae Desmodus rotundas Common Vampire Bat Uruguay, N Argentina, Paraguay, Bolivia, & N Chile north to Sonora, Nuevo León & Tamaulipas (Mexico); Margarita Isl (Venezuela); Trinidad. https://sid.erda.dk/sharelink/gBu4tuc7qz ~2Gb
15 Pteropodidae Eonycteris spelaea Cave nectar bat Bangladesh, Brunei, Cambodia, Indonesia, Java, Kalimantan, Sumatra, Sulawesi, Laos, Malaysia, Myanmar, Philippines, Singapore, Thailand, Vietnam, China, India and Timor-Leste,Gomantong Caves, Sukau, Segama, and Madai in Sabah, Niah, Sungai Tinjar, Wen et al., (2018) 1.97 Gb
16 Rhinolophidae Rhinolophus ferrumequinum Greater horseshoe bat Algeria, Morocco, & Tunisia; S Europe from Portugal to Greece & north to S England, the Netherl&s, S Germany, Austria, Czech Republic, Slovakia, & Bulgaria; Turkey, Cyprus, Georgia, & Azerbaijan; Urkrain, Crimea, & Caucacus regions; the Mediterranean coas https://www.biorxiv.org/content/10.1101/836874v1.full#F1 ~2.08 Gb
17 Pteropodidae Rousettus aegyptiacus Egyptian fruit bat Senegal & Egypt south to South Africa; Cyprus, Turkey, Jordan, Lebanon, Israel, S Syria, Yemen, Saudi Arabia, S Iraq, S. Iran, Pakistan, NW India; isls in the Gulf of Guinea (São Tomé & Príncipe); adjacent small isls. https://www.biorxiv.org/content/10.1101/836874v1.full#F1 ~1.89 Gb
18 Phyllostomidae Phyllostomus discolor Pale spear-nose bat Oaxaca & Veracruz (Mexico) to Guianas, SE Brazil, Bolivia, Paraguay, N Argentina & Peru; Trinidad; Margarita Isl (Venezeula). https://www.biorxiv.org/content/10.1101/836874v1.full#F1 ~2.10 Gb
19 Vespertilionidae Myotis myotis Greater mouse-eared bat C & S Europe, east to Ukraine; S England; most Mediterranean isls; Azores (Portugal); Asia Minor; Lebanon, Syria, & Israel. https://www.biorxiv.org/content/10.1101/836874v1.full#F1 ~2.00 Gb
20 Vespertilionidae Pipistrellus kuhlii Kuhl's pipistrelle C Europe, Near East through the Caucasus to Kazakhstan & Pakistan; SW Asia. https://www.biorxiv.org/content/10.1101/836874v1.full#F1 ~1.78 Gb
21 Molossidae Molossus molossus Velvety free-tailed bat Sinaloa & Coahuila (Mexico) to Peru, N Argentina, Paraguay, Uruguay, Brazil & Guianas; Greater & Lesser Antilles; Florida Keys (USA); Margarita Isl (Venezuela); Curaçao & Bonaire (Netherl&s Antilles); Trinidad & Tobago. https://www.biorxiv.org/content/10.1101/836874v1.full#F1 ~2.32 Gb
FAMILY GENUS SPECIES COMMON NAME DISTRIBUTION PUBLICATIONS GENOME SIZE


text:
Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes
Mohd Younis Bhat, Jayshree Advani, Pavithra Rajagopalan, Krishna Patel, Vishalakshi Nanjappa, Hitendra S. Solanki, Arun H. Patil, Firdous A. Bhat, Premendu P. Mathur, Bipin Nair, T. S.Keshava Prasad, Joseph A. Califano, David Sidransky, Harsha Gowda, Aditi Chatterjee
Carcinogenic effect of tobacco in oral cancer is through chewing and/or smoking. Significant differences exist in development of oral cancer between tobacco users and non-users. However, molecular alterations induced by different forms of tobacco are yet to be fully elucidated. We developed cellular models of chronic exposure to chewing tobacco and cigarette smoke using immortalized oral keratinocytes. Chronic exposure to tobacco resulted in increased cell scattering and invasiveness in immortalized oral keratinocytes. miRNA sequencing using Illumina HiSeq 2500 resulted in the identification of 10 significantly dysregulated miRNAs (4 fold; p ≤ 0.05) in chewing tobacco treated cells and 6 in cigarette smoke exposed cells. We integrated this data with global proteomic data and identified 36 protein targets that showed inverse expression pattern in chewing tobacco treated cells and 16 protein targets that showed inverse expression in smoke exposed cells. In addition, we identified 6 novel miRNAs in chewing tobacco treated cells and 18 novel miRNAs in smoke exposed cells. Integrative analysis of dysregulated miRNAs and their targets indicates that signaling mechanisms leading to oncogenic transformation are distinct between both forms of tobacco. Our study demonstrates alterations in miRNA expression in oral cells in response to two frequently used forms of tobacco.
Dive into the research topics of 'Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes'. Together they form a unique fingerprint.
Smokeless Tobacco Medicine & Life Sciences 100%
Smoke Medicine & Life Sciences 72%
Tobacco Products Medicine & Life Sciences 70%
MicroRNAs Medicine & Life Sciences 63%
Tobacco Medicine & Life Sciences 53%
Mouth Neoplasms Medicine & Life Sciences 20%
Mastication Medicine & Life Sciences 10%
Bhat, M. Y., Advani, J., Rajagopalan, P., Patel, K., Nanjappa, V., Solanki, H. S., Patil, A. H., Bhat, F. A., Mathur, P. P., Nair, B., Prasad, T. S. K., Califano, J. A., Sidransky, D., Gowda, H., & Chatterjee, A. (2018). Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes. Scientific reports, 8(1), [7040]. https://doi.org/10.1038/s41598-018-25498-2
Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes. / Bhat, Mohd Younis; Advani, Jayshree; Rajagopalan, Pavithra et al.
Bhat, MY, Advani, J, Rajagopalan, P, Patel, K, Nanjappa, V, Solanki, HS, Patil, AH, Bhat, FA, Mathur, PP, Nair, B, Prasad, TSK, Califano, JA, Sidransky, D, Gowda, H & Chatterjee, A 2018, 'Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes', Scientific reports, vol. 8, no. 1, 7040. https://doi.org/10.1038/s41598-018-25498-2
Bhat MY, Advani J, Rajagopalan P, Patel K, Nanjappa V, Solanki HS et al. Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes. Scientific reports. 2018 Dec 1;8(1):7040. doi: 10.1038/s41598-018-25498-2
Bhat, Mohd Younis ; Advani, Jayshree ; Rajagopalan, Pavithra et al. / Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes. In: Scientific reports. 2018 ; Vol. 8, No. 1.
@article{6a126152646a40d6b2ccedbb59fd5a0f,
title = "Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes",
abstract = "Carcinogenic effect of tobacco in oral cancer is through chewing and/or smoking. Significant differences exist in development of oral cancer between tobacco users and non-users. However, molecular alterations induced by different forms of tobacco are yet to be fully elucidated. We developed cellular models of chronic exposure to chewing tobacco and cigarette smoke using immortalized oral keratinocytes. Chronic exposure to tobacco resulted in increased cell scattering and invasiveness in immortalized oral keratinocytes. miRNA sequencing using Illumina HiSeq 2500 resulted in the identification of 10 significantly dysregulated miRNAs (4 fold; p ≤ 0.05) in chewing tobacco treated cells and 6 in cigarette smoke exposed cells. We integrated this data with global proteomic data and identified 36 protein targets that showed inverse expression pattern in chewing tobacco treated cells and 16 protein targets that showed inverse expression in smoke exposed cells. In addition, we identified 6 novel miRNAs in chewing tobacco treated cells and 18 novel miRNAs in smoke exposed cells. Integrative analysis of dysregulated miRNAs and their targets indicates that signaling mechanisms leading to oncogenic transformation are distinct between both forms of tobacco. Our study demonstrates alterations in miRNA expression in oral cells in response to two frequently used forms of tobacco.",
author = "Bhat, {Mohd Younis} and Jayshree Advani and Pavithra Rajagopalan and Krishna Patel and Vishalakshi Nanjappa and Solanki, {Hitendra S.} and Patil, {Arun H.} and Bhat, {Firdous A.} and Mathur, {Premendu P.} and Bipin Nair and Prasad, {T. S.Keshava} and Califano, {Joseph A.} and David Sidransky and Harsha Gowda and Aditi Chatterjee",
note = "Funding Information: We thank the Department of Biotechnology (DBT), Government of India for research support to the Institute of Bioinformatics (IOB), Bangalore. This work was supported by Department of Science and Technology (DST) grants (SERC/LS-439/2011 and SR/SO/HS/0208/2012) and FAMRI-funded 072017_YCSA. IOB is supported by DBT Program Support on Neuroproteomics and infrastructure for proteomic data analysis (BT/01/COE/08/05). MYB is a recipient of Junior Research Fellowship from DBT. JA and PR are recipients of Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), Government of India. Funding Information: We thank the Department of Biotechnology (DBT), Government of India for research support to the Institute of Bioinformatics (IOB), Bangalore. This work was supported by Department of Science and Technology (DST) grants (SERC/LS-439/2011 and SR/SO/HS/0208/2012) and FAMRI-funded 072017-YCSA. IOB is supported by DBT Program Support on Neuroproteomics and infrastructure for proteomic data analysis (BT/01/COE/08/05). MYB is a recipient of Junior Research Fellowship from DBT. JA and PR are recipients of Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), Government of India. Publisher Copyright: {\textcopyright} 2018 The Author(s).",
T1 - Cigarette smoke and chewing tobacco alter expression of different sets of miRNAs in oral keratinocytes
AU - Bhat, Mohd Younis
AU - Advani, Jayshree
AU - Rajagopalan, Pavithra
AU - Patel, Krishna
AU - Nanjappa, Vishalakshi
AU - Solanki, Hitendra S.
AU - Patil, Arun H.
AU - Bhat, Firdous A.
AU - Mathur, Premendu P.
AU - Nair, Bipin
AU - Prasad, T. S.Keshava
AU - Califano, Joseph A.
AU - Sidransky, David
AU - Gowda, Harsha
AU - Chatterjee, Aditi
N1 - Funding Information: We thank the Department of Biotechnology (DBT), Government of India for research support to the Institute of Bioinformatics (IOB), Bangalore. This work was supported by Department of Science and Technology (DST) grants (SERC/LS-439/2011 and SR/SO/HS/0208/2012) and FAMRI-funded 072017_YCSA. IOB is supported by DBT Program Support on Neuroproteomics and infrastructure for proteomic data analysis (BT/01/COE/08/05). MYB is a recipient of Junior Research Fellowship from DBT. JA and PR are recipients of Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), Government of India. Funding Information: We thank the Department of Biotechnology (DBT), Government of India for research support to the Institute of Bioinformatics (IOB), Bangalore. This work was supported by Department of Science and Technology (DST) grants (SERC/LS-439/2011 and SR/SO/HS/0208/2012) and FAMRI-funded 072017-YCSA. IOB is supported by DBT Program Support on Neuroproteomics and infrastructure for proteomic data analysis (BT/01/COE/08/05). MYB is a recipient of Junior Research Fellowship from DBT. JA and PR are recipients of Senior Research Fellowship from Council of Scientific and Industrial Research (CSIR), Government of India. Publisher Copyright: © 2018 The Author(s).
N2 - Carcinogenic effect of tobacco in oral cancer is through chewing and/or smoking. Significant differences exist in development of oral cancer between tobacco users and non-users. However, molecular alterations induced by different forms of tobacco are yet to be fully elucidated. We developed cellular models of chronic exposure to chewing tobacco and cigarette smoke using immortalized oral keratinocytes. Chronic exposure to tobacco resulted in increased cell scattering and invasiveness in immortalized oral keratinocytes. miRNA sequencing using Illumina HiSeq 2500 resulted in the identification of 10 significantly dysregulated miRNAs (4 fold; p ≤ 0.05) in chewing tobacco treated cells and 6 in cigarette smoke exposed cells. We integrated this data with global proteomic data and identified 36 protein targets that showed inverse expression pattern in chewing tobacco treated cells and 16 protein targets that showed inverse expression in smoke exposed cells. In addition, we identified 6 novel miRNAs in chewing tobacco treated cells and 18 novel miRNAs in smoke exposed cells. Integrative analysis of dysregulated miRNAs and their targets indicates that signaling mechanisms leading to oncogenic transformation are distinct between both forms of tobacco. Our study demonstrates alterations in miRNA expression in oral cells in response to two frequently used forms of tobacco.
AB - Carcinogenic effect of tobacco in oral cancer is through chewing and/or smoking. Significant differences exist in development of oral cancer between tobacco users and non-users. However, molecular alterations induced by different forms of tobacco are yet to be fully elucidated. We developed cellular models of chronic exposure to chewing tobacco and cigarette smoke using immortalized oral keratinocytes. Chronic exposure to tobacco resulted in increased cell scattering and invasiveness in immortalized oral keratinocytes. miRNA sequencing using Illumina HiSeq 2500 resulted in the identification of 10 significantly dysregulated miRNAs (4 fold; p ≤ 0.05) in chewing tobacco treated cells and 6 in cigarette smoke exposed cells. We integrated this data with global proteomic data and identified 36 protein targets that showed inverse expression pattern in chewing tobacco treated cells and 16 protein targets that showed inverse expression in smoke exposed cells. In addition, we identified 6 novel miRNAs in chewing tobacco treated cells and 18 novel miRNAs in smoke exposed cells. Integrative analysis of dysregulated miRNAs and their targets indicates that signaling mechanisms leading to oncogenic transformation are distinct between both forms of tobacco. Our study demonstrates alterations in miRNA expression in oral cells in response to two frequently used forms of tobacco.


A campaign has been launched to raise money to turn Kurt Cobain's childhood home into a museum.
At the end of last year, the singer's mother, Wendy O'Connor, put the bungalow in Aberdeen, Washington on the market for $500,000 (£313,000), even though it was last valued at less than $67,000 (£42,000). Her hope was that somebody would turn the property into a museum.
Now, one fan has launched a campaign to raise money to make this to happen. Portland resident and journalist Jaime Dunkle set up a GoFundMe page earlier this month featuring a video clip of her in Cobain's old bedroom. She hopes to raise $700,000 (£423,000) for the museum to "[make] sure this house is memorialised by us fans so it doesn't end up in the clutches of capitalist greed". Watch the video below.
O'Connor and Cobain's father originally purchased the house in 1969, when the singer was two years old. He lived there until his parents separated when he was nine, and also returned for another stint in the home as a teenager.


text:
Main Latest Sport News
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Mike Tyson, boxing icon, beats UFC legend Frank Mir in computer simulation
2 months ago 42955 views by Ibitoye Shittu
- Mike Tyson took on UFC heavyweight champion Frank Mir in a computer simulation
- He managed to knock out the former UFC champion after fourth round of the big fight
- Frank Mir is an American mixed martial artist and professional wrestler
American boxing legend Mike Tyson has defeated fellow countryman and former UFC heavyweight champion Frank Mir in computer simulation.
Up till now, Mike Tyson holds the record as the youngest boxer to win a heavyweight title when he was 20 years in 1986.
Frank Mir is a 40-year-old American mixed martial artist and professional wrestler who competes for Bellator MMA in the Heavyweight division.
Footage however emerged where Mike Tyson and Frank Mir were both put into the ring to fight in computer simulation in which 53-year-old won.
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Nigerian MMA fighters Adesanya, Usman missing as salaries of UFC's top fighters revealed (see list)
Both fighters were simulated in computer game UFC 2 by EA Sports with Tyson at 37 years old.
They started fighting before Mir managed to put Iron Mike on the floor in the fourth round, but a quick turn puts him on top sending a series of punches flying into Mir leaving him unconscious.
Earlier, Legit.ng had reported how boxing fans were given the chance to purchase a piece of history as Mike Tyson's famous stretched Range Rover is now up for sale at the rate of £24,000.
The famous retired American boxer used to travel with this car around Glasgow before his big boxing clash against Lou Savarese in 2000.
Tyson's Range Rover was originally owned by the Sultan of Brunei, who had the car turned into an extended limo before the American boxing legend bought it.
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Serving as an intermediary sponsor statewide for AmeriCorps VISTA to build capacity in the Out of School Time (OST) field. Since 2012, MOST has placed 96 full-year VISTA members and 99 Summer Associates at a total of 35 distinct program sites to serve communities of youth and families across the state of Maryland. Since 2012, VISTA members sponsored by MOST have collectively leveraged over $707,078 in cash resources and $319,365 worth of in-kind resources for OST programs serving youth across the state of Maryland. Additionally, VISTA members have collectively recruited and managed over 2502 volunteers, who have served a combined total of 16,443 hours in service of MD youth- for a total estimated cash value of $405,977.67 in volunteer time invested in OST programs.
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The Nath Panthi Davari Gosavi community, five of whose members were recently lynched in Dhule, has been facing ostracisation, discrimination and violence for years.
Mumbai: On May 5, 2012, three men – Supada, Hasan and Punjab – had travelled from their hometown Mohaddipur in Buldhana to Kalmana in Nagpur. They had cross-dressed in colourful saris, hoping to earn some money dancing and begging. During this time, rumours of a "sari-choli gang" roaming around the town and abducting children were rife.
The three men were "outsiders", they were dressed "strangely" and "looked suspicious". A mob allegedly gathered in a Nagpur suburb, and without provocation, caught hold of them, tied them to a light pole, beat them with sticks and stones, and lynched them in full public view. The case is pending before the Nagpur bench of the Bombay high court. Besides the mob, the police are also accused of playing a crucial role in the case – of allegedly helping the mob capture the three. All three victims belonged to the Nath Panthi Davari Gosavi community.
In 2016, another group of four men had travelled from a village in western Maharashtra to Dhule. They were dressed in yellow saris and had applied vermillion on their foreheads. Each was carrying a brass tray with photo frames of Kaalbhairavnath, their community deity, on their heads. Just hours before they entered the village, a case of housebreaking was reported. Villagers caught hold of these men and beat them brutally. The police intervened in the nick of time and they were rescued – but not before their bones were broken, head tonsured and clothes torn to tatters. These four men also belong to the Nath Panthi Davari Gosavi tribe.
A similar incident of mob violence occurred in Bijapur, Karnataka last year and the simmering anger could be contained only when the police jumped into action and whisked the three victims – two men and a minor – off the scene. The victims had travelled from western Maharashtra and their caste was later confirmed to be the same – Nath Panthi Davari Gosavi.
The five men – Dadarao Bhosale, his brother Bharat, Aappa Ingole, Bharat Malve and Raju Bhosale – who were lynched at Rainpada village in Sakri taluka in Dhule on Sunday, July 1, also belonged to the same Nath Panthi Davari Gosavi tribe.
These cases are not a result of social media-triggered rumours. Violence like this is a grim reality for the community which survives on the periphery of cities and villages, begging for alms, wandering around with cows or "entertaining" the crowd with their ingenious jokes. Some even cross-dress, or dress up as the police, jokers and Hindu seers, and remain on the move most of the year, travelling as far as Assam and Kashmir.
The semi-nomadic Nath Panthi Davari Gosavi community has for long faced ostracisation, discrimination and violence. It is one of the 42 nomadic and denotified tribes of Maharashtra – the largest among all states – with a population of about 6-7 lakh. Most among them can be found wandering in cities and villages of Maharashtra and other states. Since over 95% of the community is landless, they mostly live in makeshift plastic tents built on open grazing land outside village boundaries or in slums. The official nomenclature for the community varies in different states but all of them are unified by their belief in their community god Kalbhairavnath.
While the community was not added to the "criminal list" officially maintained by the British, it has remained an easy target for the police both in colonial and post-colonial India. Kalidas Shinde, a 35-year-old sociologist from Bombay who is from the community, says that almost every other family has a case or two registered against them. "At least today some of them carry mobile phones. Earlier they would leave home and the family back in the village would have no idea where their folks have gone to and if they would find their way back home safely," Shinde says.
Shinde is perhaps the second from the community to hold a PhD degree, that too from the prestigious Tata Institute of Social Sciences. Apart from him, the community leaders claim, only three or four have a master's degree. "Education has never been and can never be the primary focus of the community which struggles for shelter and food. Some of us managed it anyhow, working while studying and taking about three times more time than what an average privileged person with ample resources would take," Shinde adds.
This reporter, while pursuing a master's degree in law, had studied the Jat Panchayat (caste council) that is prevalent in the community and the reasons why community leaders are trusted more than the established criminal justice system. During the course of research, the writer had met Machindra Chavan in 2015, then a senior police inspector with the Pune police and now a deputy superintendent of police with General Railway Police. Chavan, who holds an MBA degree, was the first from his community to complete class X and everything that followed. Chavan, besides being an "influential person" in the community, is also considered a mass leader. His achievements and dedication towards his community has influenced a few young people to keep studying.
Chavan has created a "community directory" and identified 641 persons to have crossed the class X milestone – a number quite telling of the educational levels of the tribe. Chavan has been circulating and reprinting the copy of this directory and urging people to contact the educated ones for guidance and in times of crisis. Of these 641 persons, 227 have joined the police service, which Chavan says is also the community's way of ensuring security against state atrocities.
Each time a young person from his community is picked up by the police, or women are harassed for squatting outside temples with cows and begging, Chavan gets a call. He then either contacts the local police station or social activists from the region and gets them to intervene. "Even after the Dhule incident, Chavan was the first one to reach the spot, help the families travel from Solapur to Dhule and was involved in demanding compensation for them," Shinde says. However, The Wire has not been able to reach Chavan on the phone since this incident.
The blatant criminalisation of the community could actually explain why the tribe still believes in its Jat Panchayat. Despite its flaws and regressive stands against exercising choice in marriage and educating girls and women, and the constant fear of social boycott, several in the community still feel at least the panchayat does not criminalise them. Also, the panchayat diktats get defied regularly and people have been exerting their right to marry the person of their choice and educate girls from the community. Although a very small number, the directory has documented 25 women from the community who have either joined the police force or are working as social workers or nurses. Chavan's daughter is a fashion designer working in Pune.
"If not for these panchayats, the tribe would have disintegrated long ago and we would not come together in large numbers every time there is a crisis," Shivaji Bhosale, son-in-law of one of the victims, Bharat Malve, tells The Wire. He was referring to the spontaneous protests that were organised in Pune, Sangli and Solapur soon after the news of lynching in Dhule broke. These protests also led to the chief minister announcing Rs 5 lakh as compensation for the families of the deceased.
The nomadic and the denotified tribes do not have constitutional protection and are not covered under the Scheduled Castes and Tribes (Prevention of Atrocities) Act, 1989. In the absence of legal protection, barely any welfare scheme has been extended to the community. The National Commission for Denotified Nomadic and Semi-Nomadic Tribes, chaired by Bhiku Ramji Idate, a senior RSS functionary, has in a report compiled on the socio-economic condition of the community called them, "poorest of the poor, most marginalised and most downtrodden communities" who are subject to "social stigma, atrocity and exclusion". He has recommended that the NT/DNT tribes also be given protection under PoA, but due to lack of political will, there has not been any progress so far.
Darshan Ingole, a lawyer from the community who is practicing in the courts of Mumbai, says financial compensation, outrage and protesting on the streets every time the community is met with violence might be a natural response to injustice, but it is not enough. "Of the five people who were killed, one was only 19. Besides empathising with the community in the face of such a tragedy, we need to ask why is a 19-year-old out on the roads begging. Why is he not in school, like other boys his age?" Ingole asks.
He further adds that it was not just a chain of WhatsApp messages that killed those five men from the community, but "the apathy of the state and society that had pushed them to such a vulnerable state where the only way to survive is to wander around and beg".
"Unless the state and society are willing to address the real reasons behind my community's dismal condition, such incidents will, unfortunately, continue to occur," Ingole feels.


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Q: Activating Ng-ApiMock Mocks on Angular 9 e2e Protractor Tests I'm trying to implement ng-apimock on my Angular 9 app by
npm install @ng-apimock/core --save-dev
npm install @ng-apimock/protractor-plugin --save-dev

Then on protractor.conf.js I have added the plugin :
exports.config = {
    plugins: [{
      package: '@ng-apimock/protractor-plugin',
    }],

On my e2e test
import {Client} from '@ng-apimock/base-client';
declare const ngApimock: Client;

And inside the it () block
 ngApimock.selectScenario('login-mock, 'successful');
 element(by.id('loginBtn')).click();

BUT I don't know how to link the library to the login mock/scenario json

redpajama_set_name: RedPajamaStackExchange


text:
Video: Mike Thomas' Acrobatic Catch in the WHAC
By D.J. Byrnes on January 31, 2014 at 9:39 am @djforohio
(Trigger warning: There's some vulgarity in the video's audio.)
Since four-star WR Michael Thomas has landed at Ohio State, his biggest moments have come tearing up the Spring Game and also the production of his fellow WRs down the stretch of the 2013 season.
It appears, however, Michael Thomas is ready to take that next step. Braxton Miller said he's most excited to throw to Thomas next season. Then video of his freakish jumping ability surfaced.
Now we have another video. In this one, Thomas shows ability to high-point the ball, great body control and a fantastic "my ball" mentality that has been devoid in Ohio State wide receivers for way too long.
Granted, it would be much more impressive doing this in the Horshoe on a Saturday in front of 105,000 people, but still... it's a start.
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Personal Data that is submitted to us is bound by the Personal Data Protection Act 2010, which sets out a number of principles concerning the personal data protection in Malaysia. Personal Data provided in connection to an applicant for employment shall be used to determine his/her suitability for a position with the Company; if applicable, to determine the terms of employment or engagement. We will retain the applicant's details in our database and shall contact when a suitable opportunity arises; which might be of mutual interest. We sincerely appreciate that you considered NGCE as your prospective employer and wish you every success with your career.


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text:
Q: What is standardization's effect on p values? When you standardize variables (prior to linear regression), is it the case that it will always increase the p value of your intercept term close to or to 1?
Or, is it the case that your p value on your intercept term will depend on the particular data set you're using (i.e. that standardization doesn't necessarily direct the p value of your intercept term)?

A: Suppose "standardize" means $(X−\bar X)/SD(X)$ for all covariates and response variable. Then means of all covariates and response variable are 0. The intercept $\alpha$ is estimated by
$$\hat \alpha = \bar y -\hat \beta_1\bar x_1-\hat \beta_2\bar x_2-...-\hat \beta_k\bar x_k$$
Therefore after standardization, we have $\hat \alpha = 0$. t-statistics for testing the null hypothesis $H_o: \alpha = 0$ is zero ($t = \hat \alpha/SE(\hat\alpha)$). Obviously p-value for null hypothesis that intercept $\alpha = 0 $ is 1 because $t=0$.


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Straddling the line between "short" and "TV series" lies Mina and the Count.
Originally created in 1995 by Frederator Studios (the same people behind toons such as The Fairly OddParents and Adventure Time), it was originally created as part of Cartoon Network's "What A Cartoon!" show. In the original short, Interlude With a Vampire, the titular Count, a vampire, accidentally stumbles into the room of one Mina Harper, age 7. (He was looking for Nina Parker, age 17.) Mina quickly proves her formidity when she abruptly turns herself into his leg accessory, and despite being dragged into every manner of girly game by Mina, the Count quickly finds himself enjoying it and becomes her friend. The following shorts detailed their various goofy and spooky adventures. During its run of shorts, it migrated from Cartoon Network to Nickelodeon's Oh Yeah! Cartoons.
Among the other shorts on the various Frederator shorts shows, Mina and the Count was highly unusual. While most cartoons only saw either one or two episodes and then a full series, or one episode and then vanishing obscurity, Mina saw a full six shorts released throughout its run, making it a kind of cartoon Miniseries. It even built up a small fanbase throughout the years. But despite fans' vocal interest, it never has been--and probably never will be--expanded to a full show. Not to mention, good luck finding the shorts on DVD. Sigh--well, guess that's what YouTube is there for.
Adult Child: The Count. This is probably why he and Mina get on so well.
All Men Are Perverts: Everyone wants to seem to hit on Mrs. Frankenstein.
Bad Is Good and Good Is Bad: Seems to be the usual monster mindset. "It's monsters like you who give us all a GOOD NAME!"
Blood Lust: Well, the count is a vampire, after all. However, in one short, he's also shown eating other, "weirder" things. Just so long as it's not "mortal" food.
Bratty Teenage Daughter: Mina's older sister, Lucy.
The Bully: Nick, complete with his two nearly-identical henchmen.
Characterization Marches On: In the first short, Mina barely said anything and Igor was fairly dumb. Mina started speaking more consistently in the second short, while Igor is shown to be somewhat more intelligent in the third.
Does This Remind You of Anything?: The Count's first attempt to... ahem... "seduce" Mina.
To be fair, he thought she was 17 years old at first.
Dinner and a Show: The fourth episode, where the Count comes to dinner at Mina's house. And her sister Lucy becomes his Instant Fanclub.
Free the Frogs: Done in quite possibly the weirdest fashion ever in "Frankenfrog." The frog's already dead; Mina just brings it back with Mad Science!
Genki Girl: Mina. Mina Mina Mina Mina Mina Mina Mina!
Heroic Mime: Mina very nearly was one in the first short; her only line was "He's my best friend!" She got more talkative in the later shorts, though.
Hey, It's That Voice!: Hello there, Tara Strong, fancy meeting you here! Mark Hamill was the voice of the Count.
Tara Strong? Try Ashley Johnson.
Hypno Fool: One of the Count's vampire powers.
The Igor: Surprise! His name's Igor.
Intergenerational Friendship: She's 7, he's about 700.
Lethal Chef: Mina's culinary prowess in the fourth episode is surprising for a little girl, but still, garlic souffle is probably not one of her better ideas.
Lightning Can Do Anything: It can bring a dead frog to life as well as Mina's doll.
The Masquerade: The Count does his best to stay out of the limelight. When he has to, he parades as Mina's violin teacher.
Meaningful Name: The Count is obviously an Expy of Count Dracula. But Mina Harper is named after Mina Harker of the original Dracula novel and her bratty older sister, Lucy, is no doubt named after Lucy Westenra who ironically was Mina's best friend in the novel and in most adaptions of the tale.
Miniseries: A cartoon one, but it still kind of fits.
Missing Mom: Mina's. In the first episode, a picture on her wall seems to suggest she does have a mom, but in a later short, it's revealed that that might just be her older sister.
Monster Mash: In episode 5, The Count's monster buddies -- which more or less include Kharis, the Gill-man, and the Creature and the Missus -- come over for their monthly card night.
Morality Pet: Mina for the Count.
Kinda devolved into the Count becoming a Friendly Neighborhood Vampire after the first episode. Mina must have really rubbed off on him.
Oh Crap: The Count has a pretty fanastic moment of this in "The Vampire Who Came to Dinner."
Count: (thinking) "Well, Vlad, it looks as if you'll actually have to eat some mortal food. Ah well, it is disgusting, but as long as it's not-"
Offscreen Teleportation: Mina's game of "Peekaboo!" in episode 5.
Only One Name: In later episodes, the Count's name is revealed to be Vlad.
Our Vampires Are Different: The Count more-or-less hits most of the Classical Movie Vampire traits spot-on.
She's All Grown Up: Do a search for fanart of these cartoons, and you will invariably find pictures of an older Mina, more than likely paired with the Count.
Those Two Bad Guys: Nick's cronies, who look identically, dress identically, and even move directly in-step at all times.
This page was last edited on 11 April 2017, at 09:40.


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We understand that you may not be able to commit to active participation at this time. Anybody is free to sign up to stay connected and informed about the work of the committee. Individuals that sign up to stay connected and informed will not have input to the work plan of the committee or the benefits of committee membership. Such individuals will receive regular information about committee work including committee meeting notes, and some advanced information regarding STEM in OST resources. If you sign up to stay connected and informed you are always welcome to join the STEM Committee as an active participant at any time.


text:
Мо́ринці — пасажирський залізничний зупинний пункт Шевченківської дирекції Одеської залізниці.

Розташований біля села Моринці Корсунь-Шевченківського району Черкаської області (за 1 км). По протилежну сторону від колій розташоване село Голяки (1,5 км).

Розташований на лінії Яхни — Цвіткове між станціями Таганча (7 км) та Сотники (4 км). У 1964 року лінію Миронівка — ім. Тараса Шевченка електрифіковано.

Рух станцією
Тут мають зупинку потяги приміського сполучення. Потяги далекого сполучення не зупиняються. 2 берегові платформи розташовані обабіч двоколійної залізниці.

Маршрути потягів приміського сполучення (2 пари на день):
 Миронівка — Цвіткове
 Миронівка — ім. Тараса Шевченка (фактично слідує до Знам'янки)
Ще принаймні у 1993 році існував прямий електропоїзд Київ — Цвіткове, однак він скасований. Зараз до столиці можна потрапити з пересадкою в Миронівці.

Джерела

Посилання
 Розклад руху приміських електропоїздів по пл. Моринці

Зупинні пункти Одеської залізниці
Транспорт Корсунь-Шевченківського району
Зупинні пункти Черкаської області


text:
Q: Pipenv cant install PyQt5 I am trying to install the following packages in a pipenv virtualenv buy it has been impossible in a Mac M1. I haven't tried in another PC
I have used bot possible packages
Option 1
[packages]
pyqt5-sip = "*"
pyqt5 = "*"

Option 2
[packages]
pyqt5-sip = "==12.7.0"
pyqt5 = "==5.10.1". #This package doesn't seem to exist

I will post the different errors from te different installation methods
pipenv install
Pipfile.lock (7d18ff) out of date, updating to (bb5ccf)...
Locking [packages] dependencies...
Building requirements...
✘ Locking Failed!

ERROR:pip.subprocessor:[present-rich] Preparing metadata (pyproject.toml) exited with 1
[ResolutionFailure]:   File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/resolver.py", line 782, in _main
[ResolutionFailure]:       resolve_packages(
[ResolutionFailure]:   File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/resolver.py", line 730, in resolve_packages
[ResolutionFailure]:       results, resolver = resolve(
[ResolutionFailure]:   File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/resolver.py", line 709, in resolve
[ResolutionFailure]:       return resolve_deps(
[ResolutionFailure]:   File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/utils/resolver.py", line 1105, in resolve_deps
[ResolutionFailure]:       results, hashes, markers_lookup, resolver, skipped = actually_resolve_deps(
[ResolutionFailure]:   File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/utils/resolver.py", line 894, in actually_resolve_deps
[ResolutionFailure]:       resolver.resolve()
[ResolutionFailure]:   File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/utils/resolver.py", line 689, in resolve
[ResolutionFailure]:       raise ResolutionFailure(message=str(e))
[pipenv.exceptions.ResolutionFailure]: Warning: Your dependencies could not be resolved. You likely have a mismatch in your sub-dependencies.
  You can use $ pipenv install --skip-lock to bypass this mechanism, then run $ pipenv graph to inspect the situation.
  Hint: try $ pipenv lock --pre if it is a pre-release dependency.
ERROR: metadata generation failed

pipenv install --skip-lock
Installing dependencies from Pipfile...
An error occurred while installing pyqt5-sip! Will try again.
An error occurred while installing pyqt5! Will try again.
Installing initially failed dependencies...
Failed to install some dependency or packages.  The following have failed installation and attempted retry: [Requirement(_name='pyqt5-sip', vcs=None, req=NamedRequirement(name='pyqt5-sip', version='', req=Requirement.parse('pyqt5-sip'), extras=[], editable=False, _parsed_line=<Line (editable=False, name=pyqt5-sip, path=None, uri=None, extras=(), markers=None, vcs=None, specifier=None, pyproject=None, pyproject_requires=None, pyproject_backend=None, ireq=pyqt5-sip)>), markers=None, _specifiers='', index=None, editable=False, hashes=frozenset(), extras=(), abstract_dep=None, _line_instance=<Line (editable=False, name=pyqt5-sip, path=None, uri=None, extras=(), markers=None, vcs=None, specifier=None, pyproject=None, pyproject_requires=None, pyproject_backend=None, ireq=pyqt5-sip)>, _ireq=None), Requirement(_name='pyqt5', vcs=None, req=NamedRequirement(name='pyqt5', version='', req=Requirement.parse('pyqt5'), extras=[], editable=False, _parsed_line=<Line (editable=False, name=pyqt5, path=None, uri=None, extras=(), markers=None, vcs=None, specifier=None, pyproject=None, pyproject_requires=None, pyproject_backend=None, ireq=pyqt5)>), markers=None, _specifiers='', index=None, editable=False, hashes=frozenset(), extras=(), abstract_dep=None, _line_instance=<Line (editable=False, name=pyqt5, path=None, uri=None, extras=(), markers=None, vcs=None, specifier=None, pyproject=None, pyproject_requires=None, pyproject_backend=None, ireq=pyqt5)>, _ireq=None)]

pipenv install pyqt5
Installing pyqt5...
Error:  An error occurred while installing pyqt5!
Error text: Collecting pyqt5
  Using cached PyQt5-5.15.7.tar.gz (3.2 MB)
  Installing build dependencies: started
  Installing build dependencies: finished with status 'done'
  Getting requirements to build wheel: started
  Getting requirements to build wheel: finished with status 'done'
  Preparing metadata (pyproject.toml): started
  Preparing metadata (pyproject.toml): finished with status 'error'

  error: subprocess-exited-with-error

  × Preparing metadata (pyproject.toml) did not run successfully.
  │ exit code: 1
  ╰─> [29 lines of output]
      Traceback (most recent call last):
        File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/patched/pip/_vendor/pep517/in_process/_in_process.py", line 156, in prepare_metadata_for_build_wheel
          hook = backend.prepare_metadata_for_build_wheel
      AttributeError: module 'sipbuild.api' has no attribute 'prepare_metadata_for_build_wheel'

      During handling of the above exception, another exception occurred:

      Traceback (most recent call last):
        File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/patched/pip/_vendor/pep517/in_process/_in_process.py", line 363, in <module>
          main()
        File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/patched/pip/_vendor/pep517/in_process/_in_process.py", line 345, in main
          json_out['return_val'] = hook(**hook_input['kwargs'])
        File "/opt/homebrew/Cellar/pipenv/2022.9.21/libexec/lib/python3.10/site-packages/pipenv/patched/pip/_vendor/pep517/in_process/_in_process.py", line 160, in prepare_metadata_for_build_wheel
          whl_basename = backend.build_wheel(metadata_directory, config_settings)
        File "/private/var/folders/z8/lhf1yvnd1tb1bvq856nr_0240000gn/T/pip-build-env-t831aefc/overlay/lib/python3.9/site-packages/sipbuild/api.py", line 46, in build_wheel
          project = AbstractProject.bootstrap('wheel',
        File "/private/var/folders/z8/lhf1yvnd1tb1bvq856nr_0240000gn/T/pip-build-env-t831aefc/overlay/lib/python3.9/site-packages/sipbuild/abstract_project.py", line 87, in bootstrap
          project.setup(pyproject, tool, tool_description)
        File "/private/var/folders/z8/lhf1yvnd1tb1bvq856nr_0240000gn/T/pip-build-env-t831aefc/overlay/lib/python3.9/site-packages/sipbuild/project.py", line 585, in setup
          self.apply_user_defaults(tool)
        File "project.py", line 69, in apply_user_defaults
          super().apply_user_defaults(tool)
        File "/private/var/folders/z8/lhf1yvnd1tb1bvq856nr_0240000gn/T/pip-build-env-t831aefc/overlay/lib/python3.9/site-packages/pyqtbuild/project.py", line 70, in apply_user_defaults
          super().apply_user_defaults(tool)
        File "/private/var/folders/z8/lhf1yvnd1tb1bvq856nr_0240000gn/T/pip-build-env-t831aefc/overlay/lib/python3.9/site-packages/sipbuild/project.py", line 236, in apply_user_defaults
          self.builder.apply_user_defaults(tool)
        File "/private/var/folders/z8/lhf1yvnd1tb1bvq856nr_0240000gn/T/pip-build-env-t831aefc/overlay/lib/python3.9/site-packages/pyqtbuild/builder.py", line 69, in apply_user_defaults
          raise PyProjectOptionException('qmake',
      sipbuild.pyproject.PyProjectOptionException
      [end of output]

  note: This error originates from a subprocess, and is likely not a problem with pip.
error: metadata-generation-failed

× Encountered error while generating package metadata.
╰─> See above for output.

note: This is an issue with the package mentioned above, not pip.
hint: See above for details.
✘ Installation Failed