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text:
Weaverthorpe
Weaverthorpe is a village and civil parish in the Ryedale district of North Yorkshire, England. It is 13 miles south-west of Scarborough. Weaverthorpe has about 349 residents. Weaverthorpe is situated east of Helperthorpe.
Helperthorpe
Helperthorpe is a village in the Ryedale district of North Yorkshire, England. Photo: Wikimedia, CC BY-SA 2.0.
Butterwick
Butterwick is a village and former civil parish, now in the parish of Foxholes (1.75 miles to the east, near the village of Weaverthorpe, in the Ryedale district of North Yorkshire, England. Photo: Nigelcoates, CC BY-SA 3.0.
East Lutton
East Lutton is a hamlet in the Ryedale district of North Yorkshire, England. East Lutton is situated 1½ miles west of Weaverthorpe. Photo: Wikimedia, CC BY-SA 2.0.
Type: Village
Description: village in United Kingdom
Category: civil parish
Location: North Yorkshire, Yorkshire, England, United Kingdom, Britain and Ireland, Europe
54.1231° or 54° 7' 23" north
-0.5211° or 0° 31' 16.1" west
United Nations Location Code
GB WEV
236 feet (72 metres)
node 55441890
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Cebuano: Weaverthorpe
Dutch: Weaverthorpe
English: Weaverthorpe, North Yorkshire
French: Weaverthorpe
Polish: Weaverthorpe
Swedish: Weaverthorpe
Other Places Named Weaverthorpe
WeaverthorpeEngland, United Kingdom
Cinquefoil HillLocality
Stone Pillar HillLocality, 2 miles east
Butterwick WhinsLocality, 2 miles east
West LuttonVillage, 2½ miles west
EddsfieldAerodrome, 2½ miles east
Brompton Castle HillCastle, 7 miles north
FolktonResidential area, 8 miles northeast
River RyeStream, 8 miles west
The Wold Cottage - B&BHotel, 4½ miles east
Ganton Greyhound InnHotel, 5 miles north
Wolds Way LavenderTourist attraction, 6 miles west
The Walled GardenGarden, 7 miles northwest
Cisterna d'AstiVillage, Piedmont, Italy
Oremov LazSlovakia
HuangduanShanxi, China
GambarouVillage, Cameroon
Am KatzelbachStyria, Austria
Danceys CornerHamlet, Carneys Point, Salem County
Popular Destinations in North Yorkshire
York Middlesbrough
Scarborough Ripon
Tourists don't know where they've been, travelers don't know where they're going. - Paul Theroux
AmsterdamNetherlands Lord Howe IslandAustralia
VallettaMalta SossusvleiNamibia
About Mapcarta. Thanks to Mapbox for providing amazing maps. Data © OpenStreetMap contributors and available under the Open Database License. Text is available under the CC BY-SA 4.0 license, excluding photos, directions and the map. Based on the page Weaverthorpe. See this page's contributions. Photo: Michael Bryan, CC BY 2.0.

redpajama_set_name: RedPajamaCommonCrawl


text:
Year : 2021 | Volume : 12 | Issue : 1 | Page : 157
The effects of calorie restriction and time-restricted feeding on igf1 serum level and lipid profile in male wister rats with previous obesity
Nazanin Asghari Hanjani1, Negar Zamaninour2, Narjes Najibi1, Agha Fatemeh Hosseini3, Farinaz Nasirinezhad4, Mohammad Reza Vafa1
1 School of Public Health, Iran University of Medical Sciences, Tehran, Iran
2 Department of Minimally Invasive Surgery Research Center, Iran University of Medical Sciences (IUMS), Tehran, Iran
3 Department of Statistics and Mathematics, School of Health Management and Information Science, Iran University of Medical Sciences, Tehran, Iran
4 Physiology Research Center, Department of Physiology, Iran University of Medical Sciences, Tehran, Iran
Date of Submission 28-Jan-2020
Mohammad Reza Vafa
Professor of Nutritional Sciences, School of Public Health, Iran University of Medical Sciences, Tehran
DOI: 10.4103/ijpvm.IJPVM_38_20
Background: Calorie restriction (CR) is known as a nutritional gold standard for life extension and different studies have shown that insulin-like growth factor (IGF1) reduction through CR may be involved in CR's anti-aging effects. Besides, time-restricted-feeding (TRF) is also highlighted due to more feasibility and positive health effects. We designed this study to compare the effects of CR and TRF on IGF1 and other metabolic parameters. Methods: Fifty-two male Wistar rats (3 weeks old) were subjected to either a control (CON, n = 11) diet or high-fat diet (HFD, n = 42) for 17 weeks. In the second phase of the study, the HFD group were divided into four groups (n = 9) 1) 30% CR, 2) Night Intermittent Fasting (NIF, active phase), 3) day intermittent fasting (DIF, rest phase), and 4) Ad-Libitum (AL) with a standard diet for 10 weeks. Blood samples were collected at the end of both phases. Results: HFD increased IGF1 and deteriorated lipid profiles, except for triglycerides (P: 0.018, 0.008.0.012, 0.032) but CR in these obese subjects could not lower the IGF1 level. HDL significantly decreased in DIF compared to CON and CR (P; 0.001). Meanwhile, HOMA-IR increased in DIF and was significant compared to CR (P: 0.002). Serum glucose levels decreased in CR compared to all groups except for CON (P: 0.001). Conclusion: Data indicates the role of previous obesity on the effect of CR on the IGF1 level and highlights the effect of inappropriate time of food intake on HDL and APOA1.
Keywords: Apo A-I, calorie restriction, IGF-1, intermittent fasting
Hanjani NA, Zamaninour N, Najibi N, Hosseini AF, Nasirinezhad F, Vafa MR. The effects of calorie restriction and time-restricted feeding on igf1 serum level and lipid profile in male wister rats with previous obesity. Int J Prev Med 2021;12:157
Hanjani NA, Zamaninour N, Najibi N, Hosseini AF, Nasirinezhad F, Vafa MR. The effects of calorie restriction and time-restricted feeding on igf1 serum level and lipid profile in male wister rats with previous obesity. Int J Prev Med [serial online] 2021 [cited 2022 Jan 29];12:157. Available from: https://www.ijpvmjournal.net/text.asp?2021/12/1/157/331644
The incidence of obesity and obesity-related problems despite the considerable efforts of health care professionals is rising worldwide.[1] According to the World Health Organization's report, the number of obese people is doubling over the last 35 years and more than 50 million children at age 5 are obese.[2],[3] The major explanation for the current trend is the overconsumption of high-calorie foods and disrupted circadian rhythm. Epidemiological studies in the USA, Canada, and China have indicated that obesity incidence increases by the increment of the average amount of fat in the diet.[4],[5] Reduction of the calorie intake without malnutrition is the common strategy against obesity but beyond that, since 1935 different studies introduce, CR as a nutritional gold standard for life extension.[6] Several different pathways have been suggested to play a role in CR's mediated effects, including insulin growth factor-1 [IGF-1], Forkhead Box O (FOXO), and mammalian target of Rapamycin (mTOR), which eventually retards the damaged molecules accumulation.[7]
Previously, some different rodent studies have shown that CR can reduce IGF1 serum concentrations in rodents, and this multifaceted growth factor may be involved in CR's anti-aging and anti-cancer effects.[8] However, there is a controversy in human studies as a long term 25% calorie restriction (CR) did not lead to a IGF1 reduction while increased IGF binding1.[9] Several cellular and metabolic adaptations occur as a result of the IGF1 pathway suppression including upregulation of autophagic and apoptotic pathways, downregulation of growth pathways, increased resistance to multiple toxic agents, and increased genome stability.[9]
Moreover, due to the more feasibility and modulatory effects, intermittent fasting (IF) is known as one of the important CR's mimetics in weight loss as its primary outcome. It is noteworthy that, alternate day fasting is considered as if the protocol in most studies; while time-restricted feeding in dark/light cycle (similar to our protocol) is more practical and similar to human normal life.[8] For example, 8-week intermittent fasting specifically in the form of alternate-day fasting-induced body weight and fat mass lost specifically in obesity-prone ones.[10] Studies suggest that chronic diseases such as diabetes and cardiovascular disease are also prevented by intermittent fasting, even when there is little or no overall decrease in calorie intake.[9] Considering that light/dark cycle regulates central circadian clock which this, in turn, modifies the absorption of food, glucose or lipid transport and small peptides, depending on the moment of the day.[4] The comparison of the different effects of CR and IF in light (rest phase in rodent) and dark cycle (activity phase in rodent) against nutritional challenges that predispose an organism to obesity and related metabolic problems have yet to be investigated. Accordingly, the purpose of this study is to investigate the effect of CR and time-restricted feeding on IGF1 serum level and lipid profile in male Wister rats with previous obesity
Animals and diets
Iran University of Medical Sciences Ethics Committee approved the study protocol ((ir.iums.rec. 0327-26581) and a veterinarian regularly monitored the health status of the rats throughout the experiment. In the first phase, 52 postweaning male Wistar rats (three weeks old) were obtained from Pasteur Institute of Iran and were individually housed in cages at controlled temperature (22 ± 2 C), and humidity (50%) in a designated room under a 12-h light-dark cycle. In the accommodation period, the animals had free access to food and water. Then, the animals were divided into two groups, including control diet group (n = 11) receiving standard chow (18.8 MJ/kg with 23.4% as protein, 4.5% as fat, and 72.1% as carbohydrate, Ralston-Purina and other necessary nutrients for the growth of rats) and high-fat diet (n = 41) offering 60% of calories from milk/butter for 17 weeks. A subsample from the HFD group was housed in metabolic cages to measure the rat food intake for the second phase of the study, and CRs evaluation. The experimental diets were freshly prepared every 3 days and were kept at 0–4°C to avoid any rancidity. After significantly increasing the HFD group weight (12.5% higher body weight compared with the control group), the first phase of the study was completed. After an overnight food deprivation, a subsample from both groups (n = 6) was anesthetized by ketamine and xylazine, and blood samples were collected from the aortic vein. Blood samples were centrifuged (1500 g, 15 min at 4°C), the serum collected and stored at −80°C for further analyses. In the second phase of the study, the HFD group was divided randomly into four groups (each of 9): 1) CR, 2) Night Intermittent Fasting (IFN), 3) day intermittent fasting (IFD), and 4) Ad-Libitum (AL). The second phase of the study continued with the control group and the four derivative groups from the high-fat diet for 10 weeks [Figure 1]. Under the time-restricted feeding, rats were allowed to access the food between ZT 13 (one hour after light off) and ZT1 (1 h after light on) or vise versa [Figure 1]. At the end of this stage, blood samples were taken in similar condition to the first phase.
Figure 1: Second phase dietary pattern
The data are reported as mean ± SD. The statistical analyses were performed using SPSS software (2013- IBM SPSS Statistics for Windows, Version 22.0. Armonk NY: IBM Corp). The normality of the data distribution was checked through Kolmogorov–Smirnov test and Levene's test was used to assume the equal variance of each group. In the first phase of the study, data were analyzed through independent t-test or its nonparametric alternative, the Mann–Whitney test. In the second phase of the study and normal distribution of data, one-way analysis of variance (ANOVA), followed by Tukey posthoc tests, were used to compare the results. Otherwise, the Kruskal–Wallis and posthoc Bonferroni test were used. P values of <0.05 were considered significant.
Day intermittent fasting leads to lower HDL and APOA1
The results of biochemical analyses are presented in [Table 1]. The increment of LDL/HDL ratio, cholesterol, and total cholesterol/HDL were observed over 17 weeks of a high-fat diet, and there was no significant change in the APOB100/APOA1 ratio. Pair-wise comparison in the second phase of the study showed that the HDL level was significantly lower in DIF (rest phase) compared to CON and CR (P: 0.0001), while there were no significant changes among other parameters. Moreover, APOA1 was lower in DIF compared to the others, which was significant among CR and DIF (P: 0.012). CR increased HDL and APOA1 levels in comparison to the first phase, which was not seen in other groups (P: 0.002, 0.045).
Table 1: Biochemical parameters in the first and second phase of the study
Glucose metabolism and IGF1
A high-fat diet leads to higher fasting blood glucose, though there was no significant change in HOMA- IR and serum insulin concentration in the first phase groups (P: 0.37). Between-group analyses in the second phase of the study showed a significantly lower fasting blood glucose in CR (except for CON), and higher HOMA-IR in DIF (P: 0.0001, P: 0.002), which was significant compared to IFN. HOMA-IR also increased in IFN and DIF compared to HFD (P: 0.04, 0.004). The serum concentration of IGF1 increased in response to a high-fat diet and weight gain, while there were no significant changes in the second phase groups. Nevertheless, IGF1 increased in response to CR, compared to AL, and control food intake (P: 0.46) [Table 1].
CR is known as one of the most effective interventions against chronic diseases and a life-extension protocol from yeast to primates.[11] IGF1 as a growth factor is highlighted in CR's mediated benefits and plays an important role in cell differentiation, growth, and development. In some circumstances, this survival factor leads to higher cell proliferation, which may cause cancer and obesity, while in others acts as a cell protective agent and preserves myocytes and cardiomyocytes.[12],[13] However, the exact mechanism of CR has not been recognized yet. Data from experimental and genetic studies have indicated that a higher level of IGF1 is correlated with reduced lifespan and CR can decrease the IGF1 level.[14],[15] The first-phase results indicated that the HFD group had a higher level of IGF1. Data on IGF1 and obesity are controversial.[7],[9],[16] It seems that they have a bilateral relationship, since higher food intake increases IGF1 in those with a low level of serum concentration, while on the other hand, higher levels of IGF1 increases SREBP, cholesterol, and adipocyte differentiation.[15],[17],[18] In contrast, it seems that CR can effectively reduce IGF1 and protect the organism against cancer and other age-related diseases.[19],[20] In the second phase of the study, no reduction was observed in the serum concentration of IGF1 following CR, while surprisingly a mild increment was observed in this group compared to AL (not significant). Previously, Fontana et al. reported that long-term CR in a normal-weight person did not lead to IGF1 reduction, due to a lack of significant changes in protein intake followed by mild CR.[7] Hence, it seems that a higher level of energy restriction can decrease the IGF1 level and the involved mechanism in this kind of dietary approach differs in normal weight and obese subjects due to the disturbed insulin signaling tailored by obesity.[21] This is seen early after CR, as shown by decreased FBS and insulin resistance (compared to DIF).
A high-fat diet in the first phase of the study increased FBS significantly in the HFD group; however, the insulin concentration did not change significantly between groups. Fiorino reported that HFD started post-weaning did not change serum insulin concentration. Besides, a conjugated linoleic acid-rich diet (higher butter consumption) may activate PPARγ, which can increase free fatty acids transfer to adipose tissue, which is accompanied by higher fat pad weight and lower insulin serum concentration.[22],[23],[24] While in the CR period, higher Sirtuin may down-regulate PPARγ to improve fat hydrolysis and positively regulate PPAR-coactivator 1 (PGC1α) to coordinate the shift from glucose to fat oxidation.[25] Moreover, SIRT can enhance glucose-induced insulin secretion by inhibiting uncoupling protein 2 (UCP2).[26] In the same way, Dastbarhagh et al. reported that 8 weeks CR with or without carbohydrate limitation can enhance GLUT4 gene expression in male Wistar rats.[27] TRF did not influence FBS and insulin sensitivity favorably. It seems that TFR lasting for more than 21 h can have a positive effect on insulin resistance through an increment of beta-hydroxybutyrate, pyruvate dehydrogenase bypass, and acetyl-CoA increases.[28] Unlike the observations around insulin and FBS, DIF significantly decreased HDL and APOA1 serum concentrations compared to CON and CR, which points to the effect of inappropriate food intake time on HDL. This is noteworthy, due to the impact of HDL (rather than LDL) on cardiovascular disease.[29]
In summary, in contrast to previous studies, no changes in IGF following CR or TRF indicates the role of previous obesity in addition to calorie intake on CR-induced changes in IGF. However, the changes in this factor are studied and compared, different amount of CR or longer period of fasting may have different effects which were not studied on the other hand, the comparison between protein restriction which may have a sting role on IGF1 level with TFR (of course is not in the form of alternate-day fasting) is suggested. Moreover, this study reports an adverse effect of inappropriate food intake time on HDL and APOA1, which may be a risk factor for future cardiovascular disease and further studies in this regard may help to lead to a clear conclusion.
This research was supported by the Iran University of Medical Sciences. All authors contributed to the study conception and design. The authors' responsibilities were as follows: Nazanin Asghari Hanjani and Mohammad Reza Vafa designed the experiment., Narjes Najibi, Setareh Athari Nik Azam, and Negar Zamaninour conducted the research. Agha Fatemeh Hoseini analyzed the data; Nazanin Asghari Hanjani and Mohammad Reza Vafa wrote the manuscript. All authors' read and approved the final manuscript. Mohammad Reza Vafa had primary responsibility for final content.
This work was supported by the grant from Iran University of Medical Sciences (Grant Number: 94-03-27-26581).
Woods SC, Seeley RJ, Rushing PA, D'Alessio D, Tso P. A controlled high-fat diet induces an obese syndrome in rats. J Nutr 2003;133:1081-7.
Olsen MK, Choi MH, Kulseng B, Zhao CM, Chen D. Time-restricted feeding on weekdays restricts weight gain: A study using rat models of high-fat diet-induced obesity. Physiol Behav 2017;173:298-304.
Blüher M. Obesity: Global epidemiology and pathogenesis. Nat Rev Endocrinol 2019;15:288-98.
Hernández-García J, Navas-Carrillo D, Orenes-Piñero E. Alterations of circadian rhythms and their impact on obesity, metabolic syndrome and cardiovascular diseases. Crit Rev Food Sci Nutr 2019:1-10.
Hariri N, Thibault L. High-fat diet-induced obesity in animal models. Nutr Res Rev 2010;23:270-99.
Cummings NE, Radcliff A, Brodbeck A, Konon E, Wu J, Sherman D, et al. Decreased consumption of specific macronutrients promotes metabolic health and longevity. FASEB J 2017;31 (1_supplement):645.24.
Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO. Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell 2008;7:681-7.
de Cabo R, Fürer-Galbán S, Anson RM, Gilman C, Gorospe M, Lane MA. An in vitro model of caloric restriction. Exp Gerontol 2003;38:631-9.
Fontana L, Villareal DT, Das SK, Smith SR, Meydani SN, Pittas AG, et al. Effects of 2-year calorie restriction on circulating levels of IGF-1, IGF-binding proteins and cortisol in nonobese men and women: A randomized clinical trial. Aging Cell 2016;15:22-7.
Smyers ME. Enhanced weight and fat loss from long-term intermittent fasting in obesity-prone, low-fitness rats. Physiology & Behavior, 2021;230:113280.
Wu Z, Liu SQ, Huang D. Dietary restriction depends on nutrient composition to extend chronological lifespan in budding yeast Saccharomyces cerevisiae. PLoS 2013;8:e64448.
Berryman DE, Glad CA, List EO, Johannsson G. The GH/IGF-1 axis in obesity: Pathophysiology and therapeutic considerations. Nat Rev Endocrinol 2013;9:346-56.
Lu Y, Bradley JS, McCoski SR, Gonzalez JM, Ealy AD, Johnson SE. Reduced skeletal muscle fiber size following caloric restriction is associated with calpain-mediated proteolysis and attenuation of IGF-1 signaling. Am J Physiol Regul Integr Comp Physiol 2017;312:R806-15.
Abe T, Kazama R, Okauchi H, Oishi K. Food deprivation during active phase induces skeletal muscle atrophy via IGF-1 reduction in mice. Arch Biochem Biophys 2019;677:108160.
Ajona D, Ortiz-Espinosa S, Lozano T, Exposito F, Calvo A, Valencia K, et al. Short-term starvation reduces IGF-1 levels to sensitize lung tumors to PD-1 immune checkpoint blockade. Nat Cancer 2020;1:75-85.
Harvey AE, Lashinger LM, Otto G, Nunez NP, Hursting SD. Decreased systemic IGF-1 in response to calorie restriction modulates murine tumor cell growth, nuclear factor-κB activation, and inflammation-related gene expression. Mol Carcinog 2013;52:997-1006.
Nam SY, Lee EJ, Kim KR, Cha BS, Song YD, Lim SK, et al. Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone. Int J Obes Relat Metab Disord 1997;21:355-9.
Bailey-Downs LC, Sosnowska D, Toth P, Mitschelen M, Gautam T, Henthorn JC, et al. Growth hormone and IGF-1 deficiency exacerbate high-fat diet–induced endothelial impairment in obese lewis dwarf rats: Implications for vascular aging. J Gerontol A Biol Sci Med Sci 2012;67:553-64.
O'Flanagan CH, Smith LA, McDonell SB, Hursting SD. When less may be more: Calorie restriction and response to cancer therapy. BMC Med 2017;15:106.
Yu D, Fontana L, Lamming DW. Aging: Mechanisms, signaling and dietary intervention, in principles of nutrigenetics and nutrigenomics. Princ Nutrigenet Nutrigenomics 2020:395-401. doi: 10.1016/B978-0-12-804572-5.00054-9.
Espelund U, Bruun JM, Richelsen B, Flyvbjerg A, Frystyk J. Pro-and mature IGF-II during diet-induced weight loss in obese subjects. Eur J Endocrinol 2005;153:861-9.
Fiorino P, Américo AL, Muller CR, Evangelista FS, Santos F, Leite AP, et al. Exposure to high-fat diet since post-weaning induces cardiometabolic damage in adult rats. Life Sci 2016;160:12-7.
Cardinal KM, de Moraes ML, Borille R, Lovato GD, Ceron MS, de Marques Vilella L, et al. Effects of dietary conjugated linoleic acid on broiler performance and carcass characteristics. J Agric Sci 2017;9:208.
Raff MJO, Tholstrup T, Basu S, Nonboe P, Sørensen MT, Straarup EM. A diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young men-DTU Orbit (19/12/2018) 2018;19:12.
Ramadori G, Lee CE, Bookout AL, Lee S, Williams KW, Anderson J, et al. Brain SIRT1: Anatomical distribution and regulation by energy availability. J Neurosci 2008;28:9989-96.
Moynihan KA, Grimm AA, Plueger MM, Bernal-Mizrachi E, Ford E, Cras-Méneur C, et al. Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice. Cell Metab 2005;2:105-17.
Dastbarhagh H, Kargarfard M, Abedi H, Bambaeichi E, Nazarali P. Effects of food restriction and/or aerobic exercise on the GLUT4 in type 2 diabetic male rats. Int J Prev Med 2019;10:139.
Park S, Yoo KM, Hyun JS, Kang S. Intermittent fasting reduces body fat but exacerbates hepatic insulin resistance in young rats regardless of high protein and fat diets. J Nutr Biochem 2017;40:14-22.
Bartlett J, Predazzi IM, Williams SM, Bush WS, Kim Y, Havas S, et al. Is isolated low HDL-C a CVD risk factor? New insights from the framingham offspring study. Circ Cardiovasc Qual Outcomes 2016;9:206-12.
[Table 1]
Hanjani NA
Zamaninour N
Najibi N
Hosseini AF
Nasirinezhad F
Vafa MR
Apo A-I
calorie restriction


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The leader of the main opposition party in Pakistan Asif Ali Zardari has appealed for calm after a suicide car bombing at a supporters' rally killed 37 people. The blast happened on the last day of campaigning before Monday's general election. Chris Morris reports from Islamabad.
This election campaign is ended as it began with acts of violence casting a long shadow. A car was driven into a crowd waiting for food after an election meeting in the town of Parachinar, in a region where Islamist militancy has been on the rise. Eyewitnesses say the car blew up, scattering body parts across the street. Many of the dead and wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy, but security concerns remain high.
Thousands of ethnic Albanians have poured onto the streets of Prishtina, the capital of the Serbian province of Kosovo, to celebrate its imminent unilateral declaration of independence. In the Serbian capital Belgrade, about 1000 demonstrators protested at the loss of territory they considered their heartland. Kosovo's Prime Minister Hashim Thaci said the influence of Belgrade had ended. Independence was a done deal and Kosovo must look to the future. From Prishtina, Helen Fawkes reports.
The countdown to Kosovo's independence is on. Final preparations are being made for the celebrations. For some, the party has already started. On Sunday, hundreds of thousands of ethnic Albanians are expected on the streets of the capital. Many people here are flying the Albanian flag. Kosovo's new flag is yet to be unveiled. There is concern this may spark sporadic violence. 16000 NATO troops are based in Kosovo and security is tight.
The UN High Commissioner for Refugees Antonio Guterres has said it's time to start considering the possibility of organizing the voluntary return of some of the millions of Iraqis who have fled their homes because of the violence. Mr. Guterres has agreed with the Iraqi government for an assessment of conditions on the ground to take place to see if it is safe for refugees to return.
Returns can only take place voluntarily in safety and dignity and people must see their basic problems solved. There is a lot of work to be done. And we will be working there together with the Iraqi government in an assessment in order to look at the future opportunities of return that we hope will be able to take place in a way that will contribute to national reconciliation and to the reconstruction of the country.
A former Nazi SS member who was convicted in his absence of war crimes in Italy has started a prison sentence in southern Italy following his extradition from Canada. The man, Michael Seifert, was found guilty in 2000 of killings committed while he was a camp guard in northern Italy in the last year of the Second World War
At the start of his tour of Africa, President Bush has urged an end to violence in Kenya. He said that Secretary of State Condoleezza Rice would underline that message in her forthcoming visit there. But speaking in Benin, the first stop on his tour, Mr. Bush said Africa's many conflicts were not the main focus of his visit. He wanted to highlight success stories.
There's a lot more work to be done. One of the reasons I've come on this trip is to say, look at the successes we've had. We, by the way, is not American successes; these are joint successes. And look at the work that needs to be done.
Tens of thousands of Armenians have held a rally in the capital Yerevan in support of one of the main opposition candidates in Tuesday's presidential election. Levon Ter-Petrosyan has accused the authorities of preparing to rig the vote. President Robert Kocharian is stepping down after serving the maximum two terms. Observers say power is likely to transfer to his chosen successor, the Prime Minister Serzh Sarkisian.
A major scientific conference in the United States has heard that robots with artificial intelligence could become as clever as humans within 20 years. The inventor and author Dr. Ray Kurzweil told the meeting of the American Association for the Advancement of Science that progress in molecular computing would provide what he called the hardware for human level artificial intelligence by the 2020s. He said that already more than 20 regions of the human brain had been modeled and stimulated.
A Brazilian film about police violence has won the Golden Bear, the top prize at the Berlin Film Festival. The film, The Elite Squad directed by Jose Padilha portrays the operations of a paramilitary police unit in Rio de Janeiro. The American film maker Paul Thomas Anderson won best director for There Will Be Blood. The best actor award went to the Iranian Reza Naji for his performance in The Song of Sparrows as an ostrich farmer who moves to Tehran when he loses his job.
支持普特英语听力就多多发帖吧!您们的参与是对斑竹工作最大的肯定与支持!如果您觉得还不错,推荐给周围的朋友吧~
nickcj
nickcj 当前离线
尚书
The leader of the main opposition Party in Pakistan Asif Ali Zardari has appealed for calm after a suicide car bombing at a supporters' rally, killed 37 people. The blast happened in the last day of campaigning before Monday's general election. Chris Morris reports from Islamabad.
This election campaign has ended as it begun with acts of violence casting a long shadow, a car was driven into a crowd, waiting for food after an election meeting in the town of Parachinar, in the region where Islamist militancy has been on the rise, eye-witnesses say the car blew up, scattering body parts across the street, many of the deaden wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy, but security concerns remain high.
Thousands of ethnic Albanians have poured onto the streets of Priština, the capital of the Serbian province of Kosovo, to celebrate its eminent unilateral declaration of independence. In the Serbian capital Belgrade, about a thousand demonstrators protested the loss of territory they considered their heartland. Kosovo's Prime Minister Hashim Thaci said the influence of Belgrade had ended, independence was a done deal and Kosovo must look to the future. From Priština, Helen Fawkes reports.
The countdown to Kosovo's independence is on. Final preparations are being made for the celebrations, but some the Party has already started. On Sunday, hundreds of thousands of ethnic Albanians are expected on the streets of the capital, many people here are flying the Albanians flag, Kosovo's new flag is yet to be unveiled. This concern has may spark sporadic violence, 16,000 NATO troops are based in Kosova, and security is tight.
The UN High Commissioner for Refugees Antonio Guterres has said it's time to start considering the possibility of organizing the voluntarily return of some of the millions of Iraqis are fled their homes because of the violence. Mr. Guterres has agreed with the Iraqi government for an assessment of conditions on the ground to take place to see if it's safe for refugees to return.
"Returns can only take place voluntarily in safety and legality, and people must see their basic problems, so, there is a lot of work to be done, and will be looking together with the Iraqi government in an assessment, uh, in order to look at future opportunities' return, that we helped will be able to take place in the way that will consequent to nationally conciliation and to the reconciliation of the country.
A formal Nazi SS member who was convicted in his absence of war crimes in Italy has started a prison sentence in southern Italy following his extradition from Canada, the man Michael Seifert was found guilty in 2000 of killing's committed while he was comes guard in northern Italy in the last year of the Second World War.
Of the start of his tour of Africa, President Bush has urged an end to violence in Kenya, he said his Secretary of State Condoleezza Rice would underline that message in her forthcoming visit there. The speaking in Benin, the first stop on his tour, Mr. Bush said Africa's many conflicts were not the main focus of visit, he wants to highlight success stories.
"It's a lot more work to be done when the regions come on this trip let's say, look at the successes we've had, we've been, by the way, not American's successes, these are joint successes, and look at the work needs to done."
Tens of thousands of Armenians have held a rally in the capital Yerevan, and support one of the main opposition candidates in Tuesday's presidential election. Levon Ter-Petrosian has accused the authorities of preparing to regular vote. President Robert Kocharian is stepping down after serving the maximum 2 terms, observers say President are likely to transfer to his chosen successor, the Prime Minister Serzh Sargsyan.
A major scientific conference in the United States has heard that robots with artificial intelligence could become as clever as human within 20 years. The inventor and author Dr. Ray Kurzweil told the meeting of the American Association for the Advancement of Science, that progress and molecular computing would provide what he called the hardware for human level artificial intelligence by the 2020s. He said it already more than 20 regions of the human brain had been modeled and stimulated.
A Brazilian film about police violence has won the Golden Bear, the top prize of the Berlin Film Festival. The film "The Elite Squad" directed by Jose Padilha, portrays the operations of a paramilitary police unit in Rio de Janeiro. The American filmmaker Paul Thomas Anderson won best director for "There Will Be Blood", the Best Actor Award went to the Iranian Reza Naji for his performance in "the Song of Sparrows" as an ostrich farmer who move to Iran when he loses his job.
hshlj2008
hshlj2008 当前离线
on nickcj
This election campaign has ended as it began with acts of violence casting a long shadow, a car was driven into a crowd, waiting for food after an election meeting in the town of Parachinar, in the region where Islamist militancy has been on the rise, eye-witnesses say the car blew up, scattering body parts across the street, many of the dead or wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy, but security concerns remain high.
The countdown to Kosovo's independence is on. Final preparations are being made for the celebrations, but some the Party has already started. On Sunday, hundreds of thousands of ethnic Albanians are expected on the streets of the capital, many people here are flying the Albanian flag, Kosovo's new flag is yet to be unveiled. There's concern is made sparks sporadic violence, 16,000 NATO troops are based in Kosova, and security is tight.
The UN High Commissioner for Refugees, Antonio Guterres, has said it's time to start considering the possibility of organizing the voluntary return of some of the millions of Iraqis who fled their homes because of the violence. Mr. Guterres has agreed with the Iraqi government for an assessment of conditions on the ground to take place to see if it's safe for refugees to return.
"Returns can only take place voluntarily in safety and legality, and people must see their basic problems, so, there is a lot of work to be done, and we'll be working together with the Iraqi government in an assessment, uh, in order to look at future opportunities' return, that we helped will be able to take place in the way that will consequent to nationally conciliation and to the reconciliation of the country.
A formal Nazi SS member who was convicted in his absence of war crimes in Italy has started a prison sentence in southern Italy following his extradition from Canada, the man Michael Seifert was found guilty in 2000 of killings committed while he was a comes guard in northern Italy in the last year of the Second World War.
Of the start of his tour of Africa, President Bush has urged an end to violence in Kenya, he said his Secretary of State Condoleezza Rice would underline that message in her forthcoming visit there. The speaking in Benin, the first stop on his tour, Mr. Bush said Africa's many conflicts were not the main focus of his visit, he wanted to highlight success stories.
"It's a lot more work to be done when the regions come on this trip let's say, look at the successes we've had, we've been, by the way, not America's successes, these are joint successes, and look at the work needs to done."
Tens of thousands of Armenians have held a rally in the capital Yerevan, and support one of the main opposition candidates in Tuesday's presidential election. Levon Ter-Petrosian has accused the authorities of preparing to rigor the vote. President Robert Kocharian is stepping down after serving the maximum 2 terms, observers say President are likely to transfer to his chosen successor, the Prime Minister Serzh Sargsyan.
A major scientific conference in the United States has heard that robots with artificial intelligence could become as clever as humans within 20 years. The inventor and author Dr. Ray Kurzweil told the meeting of the American Association for the Advancement of Science, that progress in molecular computing would provide what he called "the hardware" for human-level artificial intelligence by the 2020s. He said there's already more than 20 regions of the human brain that had been modeled and stimulated.
A Brazilian film about police violence has won the Golden Bear, the top prize of the Berlin Film Festival. The film "The Elite Squad" directed by Jose Padilha, portrays the operations of a paramilitary police unit in Rio de Janeiro. The American filmmaker Paul Thomas Anderson won best director for "There Will Be Blood", the Best Actor Award went to the Iranian Reza Naji for his performance in "the Song of Sparrows" as an ostrich farmer who moved to Iran when he loses his job.
本文章由 nickcj于 今天, 11:22 AM 重新编辑过
waijiao
waijiao 当前离线
on hshlj2008
The leader of the main opposition Party in Pakistan Asif Ali Zardari has appealed for calm after a suicide car bombing at a supporters' rally, killed 37 people. The blast happened on the last day of campaigning before Monday's general election. Chris Morris reports from Islamabad.
This election campaign has ended as it began with acts of violence casting a long shadow, a car was driven into a crowd, waiting for food after an election meeting in the town of Parachinar, in the region where Islamist militancy has been on the rise, eye-witnesses say the car blew up, scattering body parts across the street, many of the dead and wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy, but security concerns remain high.
Thousands of Ethnic Albanians have poured onto the streets of Priština, the capital of the Serbian province of Kosovo, to celebrate its imminent unilateral declaration of independence. In the Serbian capital Belgrade, about a thousand demonstrators protested the loss of territory they considered their heartland. Kosovo's Prime Minister Hashim Thaci said the influence of Belgrade had ended, independence was a done deal and Kosovo must look to the future. From Priština, Helen Fawkes reports.
The countdown to Kosovo's independence is on. Final preparations are being made for the celebrations, but some the Party has already started. On Sunday, hundreds of thousands of Ethnic Albanians are expected on the streets of the capital, many people here are flying the Albanian flag, Kosovo's new flag is yet to be unveiled. There's concern this may spark sporadic violence, 16,000 NATO troops are based in Kosovo, and security is tight.
At the start of his tour of Africa, President Bush has urged an end to violence in Kenya, he said his Secretary of State Condoleezza Rice would underline that message in her forthcoming visit there. The speaking in Benin, the first stop of his tour, Mr. Bush said Africa's many conflicts were not the main focus of his visit, he wanted to highlight success stories.
Tens of thousands of Armenians have held a rally in the capital Yerevan, and support one of the main opposition candidates in Tuesday's presidential election. Levon Ter-Petrosian has accused the authorities of preparing to rig the vote. President Robert Kocharian is stepping down after serving the maximum 2 terms, observers say President are likely to transfer to his chosen successor, the Prime Minister Serzh Sargsyan.
Tina12
Tina12 当前离线
This election campaign is ended as it began with acts of violence casting a long shadow. A car was driven into a crowd waiting for food after an election meeting in the town of Parachinar in a region where Islamist militancy has been on the rise. Eye-witnesses say the car blew up, scattering body parts across the street. Many of the dead and wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy, but security concerns remain high.
Thousands of ethnic Albanians have poured onto the streets of Pristina, the capital of the Serbian province of Kosovo, to celebrate its eminent unilateral declaration of independence. In the Serbian capital Belgrade, about 1,000 demonstrators protested a loss of territory they considered their heartland. Kosovo's Prime Minister Hashim Thaci said the influence of Belgrade had ended, independence was a done deal and Kosovo must look to the future. From Pristina, Helen Fawkes reports.
The countdown to Kosovo's independence is on. Final preparations are being made for the celebrations, but some, the party, has already started. On Sunday, hundreds of thousands of ethnic Albanians are expected on the streets of the capital. Many people here are flying the Albanian flag. Kosovo's new flag is yet to be unveiled. There is concern this may sparkle spread of violence. 16,000 NATO troops are based in Kosovo and security is tight.
The UN High Commissioner for Refugees Antonio Guterres has said it's time to start considering the possibility of organizing the voluntary return of some of the millions of Iraqis who've fled their homes because of the violence. Mr. Guterres has agreed with the Iraqi government for an assessment of conditions on the ground to take place to see if it is safe for refugees to return.
"Returns can only take place voluntarily in safety and dignity and people must see their basic problems solved. There is a lot of work to be done. And we will be working there together with the Iraqi government in the assessment in order to look at future opportunities of return that we hope will be able to take place in a way that will contribute to national reconciliation and to the construction of the country. "
At the start of his tour of Africa, President Bush has urged an end to violence in Kenya. He said that Secretary-General of State Condoleezza Rice would underline that message in her forthcoming visit there. But speaking in Benin, the first stop of his tour, Mr. Bush said Africa's many conflicts were not the main focus of his visit. He wanted to highlight success stories.
"There's a lot more work to be done. One of the reasons I've come on this trip is to say, look at the successes we've had. We, by the way, is not American successes; these are joint successes. And look at the work that needs to be done."
Tens of thousands of Armenians have held a rally in the capital Yerevan in support of one of the main opposition candidates in Tuesday's presidential election. Levon Ter-Petrosyan has accused the authorities of appearing to rig the vote. President Robert Kocharian is stepping down after serving the maximum two terms. Observers say power is likely to transfer to his chosen successor the Prime Minister Serzh Sarkisian.
A major scientific conference in the United States has heard that robots with artificial intelligence could become as clever as humans within 20 years. The inventor and author Dr. Ray Kurzweil told the meeting of the American Association for the Advancement of Science that progress in molecular computing would provide what he called the hardware for human level artificial intelligence by the 2020s. He says that already more than 20 regions of the human brain have been modeled and stimulated.
A Brazilian film about police violence has won the Golden Bear, the top prize of the Berlin Film Festival. The film, The Elite Squad directed by Jose Padilha portraits the operations of a paramilitary police unit in Rio de Janeiro. The American film-maker Paul Thomas Anderson won best director for There Will Be Blood. The best actor award went to the Iranian Reza Naji for his performance in The Song of Sparrows as an ostrich farmer who moves to Tehran when he loses his job.
小长脖鹿
小长脖鹿 当前离线
On waijiao
"Returns can only take place voluntarily in safety and legality, and people must see their basic problems, so, there is a lot of work to be done, and we'll be working together with the Iraqi government in an assessment, uh, in order to look at future opportunities of return, that we hope will be able to take place in the way that will contribute to national reconciliation and to the reconstruction of the country.
我是宇宙超级霹雳勇猛无敌小长脖鹿
zcb-kite-fly
zcb-kite-fly 当前离线
Homework(2.17)
The leader of the main opposition party in Pakistan,Asif Ali Zardari(Benazir Bhutton's husband) has appealed for calm after a suicide car bombing at a supporters' rally killed 37 people.The blast happened in the last day of campaigning before Monday's general election.Chris Morris reports from Islamabad.
"This election campaign has ended as it bagan with acts of violence casting a long shadow,a car was driven into a crowd,waiting for food after the election meeting in the town of P*,in the region where Islamic militancy has been on the raise.Eye witnesses say the car blew up,scattering bodies parts across the street.Many of the dead and wounded were the supporters of Pakistan's People's party.The election is supposed to be an important landmark in the transation to civil democracy.But security concern remains high."
Thousands of ethnic Albanians have poured onto the street of pristina,the capital of Serbia province of Kosovo,to celebrate it eminent unilateral declaration of independence.In the Serbia capital Belgrade,about a thousand demonstrators protested the lose of territory,they considered as their heart land.Kosovo's Prime Minister / said the influence of Belgrade had ended.Independence was a donedeal and Kosovo must look to the future.From Pristina,Helen Fox reports.
"The countdown to Kosovo's independence is on.Final preparations are being made for the celebrations.The sun-- the party has already started.On Sunday,hundreds and thousands of ethnic Albanians are expected on the streets of capital.Many people here are flying the Albanian flag.Kosovo's new flag is yet to be unveiled.This concerns that this may spark spread violence.16,000 NATO troops are based in Kosovo and security is tight."
The UN high commissioner for refugees,* has said it's time to start considering the possibility of organizing the voluntary return of some of millions of Iraqis fled their home because of the violence.Mr.* has agreed with Iraq government from assessment of conditions on the growing to take place to see of it is safe for refugees to return.
"Returns can only take place voluntarily in safely and dignity.And people must see their basic problems.So there is a lot of work to be done.And we're doing together with Iraqi government in the assessment,uh,in order to look at future opportunities of return that we hope will be able to take place in a way that will consequent to nationally conciliation and to reconciliation of the country."
A former Nazi SS member who was convicted in his absence of war crimes in Italy has started a prison center in sountern Italy following his extradition from Canada.The man // was found guilty in 2000 of killings committed when he was conrride guard in northen Italy in the last year of Second World War.
At the start of his tour of Africa,president Bush has urged an end of violence in Kenya.He said Secretary of State Condeleezza Rice would underline a message of her forthcoming visit there.Mr.Bush said Africa's many conflicts were not the main forces,he wanted to highlight success of stories.
"It's a lot of more work to be done when we come on this trip,let's say,look at the success we'd have,we've been,by the way,not America's successes,there are joint successes.And look at the work that needs to be done."
Tens of thousands of Armenians have held rally in capital / in support of one of main opposition candidate in Tuesday's presidential election./ has accused the authories of preparing to rig the vote.President / is stepping down after serving the maxium two terms.Observers say president is likely to transfer his choosen successor,the Prime Minister //.
A major scientific conference in United States has heard a robot with artifical intelligence would become as clever as humans within 20 years.The inventor and author // told the meeting of American Assosiation for Advancement of science that progress in molecular computing would provide what it called the hardware for human level arifical intelligence by the 2020s.He said there's already more than 20 regions of human brain have been modeled and stimulated.
A Brazilian film about police violence has won the Golden Bear,the top prize of the Berlin Film Festival.The film' Elite Squad'directed by Jose Padilha ,portrays the operations of a paramilitary police unit in Rio de Janeiro.The American film maker Paul Thomas Anderson won best director for 'There will be blood'.The Best Actor Award went to the Iranian / for his perfermance in 'the song of Sparrows'as an / farmer who moved to Iran when he loses his job.
barbaragx
barbaragx 当前离线
On 小长脖鹿
This election campaign was ended as it began with acts of violence casting a long shadow, a car was driven into a crowd, waiting for food after an election meeting in the town of Parachinar, in the region where Islamist militancy has been on the rise, eye-witnesses say the car blew up, scattering body parts across the street, many of the dead and wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy, but security concerns remain high.
The countdown to Kosovo's independence is on. Final preparations are being made for the celebrations, for some the Party has already started. On Sunday, hundreds of thousands of Ethnic Albanians are expected on the streets of the capital, many people here are flying the Albanian flag, Kosovo's new flag is yet to be unveiled. There's concern this may spark sporadic violence, 16,000 NATO troops are based in Kosovo, and security is tight.
The UN High Commissioner for Refugees, Antonio Guterres, has said it's time to start considering the possibility of organizing the voluntary return of some of the millions of Iraqis who have fled their homes because of the violence. Mr. Guterres has agreed with the Iraqi government for an assessment of conditions on the ground to take place to see if it's safe for refugees to return.
"Returns can only take place voluntarily in safety and dignity, and people must see their basic problems, so, there is a lot of work to be done, and we'll be working together with the Iraqi government in the assessment, uh, in order to look at future opportunities of return, that we hope will be able to take place in the way that will contribute to national reconciliation and to the reconstruction of the country.
A former Nazi assassin member who was convicted in his absence of war crimes in Italy has started a prison sentence in southern Italy following his extradition from Canada, the man Michael Seifert was found guilty in 2000 of killings committed while he was a camp guard in northern Italy in the last year of the Second World War.
"There'sa lot more work to be done when the regions have come on this trip let's say, look at the successes we've had, we've been, by the way, not America's successes, these are joint successes, and look at the work needs to done."
A major scientific conference in the United States has had that robots with artificial intelligence could become as clever as humans within 20 years. The inventor and author Dr. Ray Kurzweil told the meeting of the American Association for the Advancement of Science, that progress in molecular computing would provide what he called "the hardware" for human-level artificial intelligence by the 2020s. He said there's already more than 20 regions of the human brain that had been modeled and simulated.
A Brazilian film about police violence has won the Golden Bear, the top prize of the Berlin Film Festival. The film "The Elite Squad" directed by Jose Padilha, portrays the operations of a paramilitary police unit in Rio de Janeiro. The American filmmaker Paul Thomas Anderson won best director for "There Will Be Blood", the Best Actor Award went to the Iranian Reza Naji for his performance in "the Song of Sparrows" as an ostrich farmer who moves to Iran when he loses his job.
iiwsh
iiwsh 当前离线
on barbaragx
The leader of the main opposition party in Pakistan Asif Ali Zardari has appealed for calm after a suicide car bombing at a supporters' rally killed 37 people. The blast happened on the last day of campaigning before Monday's general election. Chris Morris reports from Islamabad.
"This election campaign is ended as it began with act of violence casting a long shadow. A car was driven into a crowd waiting for food after an election meeting in the town of /, in a region where Islamic militancy has been on the rise. Eyewitnesses say the car blew up scattering body parts across the street. Many of the dead and wounded were supporters of the Pakistan People's Party. The election is supposed to be an important landmark in the transition to civilian democracy. But security concerns remain high. "
Thousands of ethnic Albanians have poured onto the streets of Pristina, the capital of the Serbian province of Kosovo to celebrate its imminent unilateral declaration of independence. In the Serbian capital, Belgrade, about a thousand demonstrators protest at the loss of territory that they consider their heartland. Kosovo's prime minister, Hashim Thaci, said the influence of Belgrade had ended and independence was a done deal and Kosovo must glue to the future. From Pristina, Helen Fawkes reports.
"The countdown to Kosovo's independence is on. Final preparation has been made for the celebrations. The song, the party has already started. On Sunday hundreds of thousands of ethnic Albanians are expected on the streets of the capital. Many people here are flying the Albanian flag. Kosovo's new is yet to be unveiled. There's concern this may spark sporadic violence. 16000 NATO troops are based in Kosovo and security is tight. "
The UN high commissioner for refugees, Antonion Guterres, has said it's time to start considering the possibility of organizing the voluntary return of some of the millions of Iraqis that had fled their homes because of the violence. Mr. Guterres has agreed with the Iraqi government for an assessment of condition on the ground to take place to see if it's safe for refugees to return.
"Returns can only take place voluntarily in safety and dignity. And people must see their basic problems, or there's a lot of work to be done. And we will be working together with the Iraqi government in an assessment in order to look at the future opportunities of return that we hope will be take place in a way that we will contribute to national conciliation and to the reconstruction of the country. "
A former Nazi SS member who was convicted in his absence of war crimes in Italy has started a prison sentence in southern following his extradition from Canada. The man, /, was found guilty in 2000 of killings committed while he was a camp guard in northern Italy in the last year of the Second World War.
At the start of his tour of Africa, President Bush has urged an end to violence in Kenya. He said that the Secretary of State, Condoleezza Rice, would underline that message in her forthcoming visit there. When speaking in Benin, the first stop in his tour, Mr. Bush said Africa's many conflicts were not the main focus of his visit. He wanted to highlight success stories.
"There's a lot more work to be done. One of the reasons I've come on this trip is to say, look at these successes we've had. 'We', by the way, is not American successes, these are, joint successes. And look at the work that needs to be done. "
Tens of thousands of Armenians have held their rallies in the capital / in support of one of the main opposition candidates in Tuesday's presidential election. / has accused the authorities of preparing to rig the vote. President / is stepping down after serving the maximum, two terms. Observers say power is likely to transfer to his chosen successor, the prime minister, /.
A major scientific conference in the United States has heard that robots with artificial intelligence could become as clever as humans within 20 years. The inventor and author, Dr. /, told the meeting of the American Association for the advancement of science that progress in molecular computing would provide what he called the hardware for human level artificial intelligence by the 2020s. He said that already more 20 regions of the human brain had been modeled and stimulated.
A Brazilian film about police violence has won the Golden Bear, the top prize at the Berlin film festival. The film, the Elite Squad, directed by /, portrays the operations of a paramilitary police unit in Rio de Janeiro. The American filmmaker, Paul Thomas Anderson, won the Best Director for There Will Be Blood. The Best Actor Award went to the Iranian / for his performance in The Song of Sparrows as an ostrich farmer who moves to Tehran when he loses his job.
seaside20042010
seaside20042010 当前离线
BBC news with Fiona Mcdonald
The leader of the main opposition party in Pakistan ** has appealed for calm after a suicide car bombing at a supporter's rally killed 37 people. The blast happened on the last day of campaigning before Monday's general election. Christlame reports from Islamic Bagdad.
This election campaign has ended as it began with excessive violence casting a long shadow. A car was driven into a crowd waiting for food after an election meeting in a town of *in a region where Islamic militancy has been on the rise. A witness said the car blew up scattering the body parts across the street. Many of the dead and wounded were supporters of Pakistan people's party. The election is supposed to be a landmark in a transition to civilian democracy. But security concerns remain high.
Thousands of ethical ** poured out on the streets of ** the capital of the Serbian province of Kosovo to celebrate its imminent unilateral declaration of independence. In the Serbian capital, B*, thousands of demonstrators protested the loss of territory they considered as their heart land. Kosovo's prime minister**, said the influence of * had ended. The independence was a done deal and Kosovo must live to the future. From **, Helen Fore reports.
The countdown to the Kosovo's independence is on. Final preparation has been made for celebrations, the song, the party has already started. On Sunday, hundreds of thousands of ethnical ** are expected on the streets of the capital. Many people here are flying the ** flag. Kosovo's new flag is yet to be unveiled. There is concerns is may spark sporadic violence. 16 thousand nato troops based in Kosovo and the security is tight.
The UN high commissioner for refugees Tony* has said it's time to start considering the possibility of organizing the voluntary return of some of the billions Iraqis fled their homes because of the violence. Mr.* has agreed with the Iraqi government from an assessment of condition on the ground to take place to see if it is safe for the refugees to return.
"returns can take place voluntarily with safety and dignity and people must see their basic problems or there's a lot of work to be done. And we will be working good together with Iraq government in a assessment in order to look at future opportunities in reason. And we hope we'll be able to take place in a way that will contribute to national conciliation and to re-conciliation to the country.
A former Nazi ss member who has convicted his absence of war crime in Italy has started the prison-sentence in southern Italy following his extradition in Canada. The man* was found guilty in 2000 of killings// when he became guard in northern Italy in the last year of the second world war.
At the start of tour of Africa, president Bush has urged anti-violence in Kenya. He said the secretary of state ** Rise would underline their message in their forth coming visit there. The speaking in *, the first stop of tour, Mr bush said African many conflicts were not the main focus of his visit. He wanted to highlight the success stories.
'there's a lot work to be done. One of reasons I come on this trip is to say look at this success we gain. We'll be, by the way, not American success. It's a joint success and look at the work needs to be done. "
Tens of thousands of ** held rally in the capital * and support one of the main opposition candidates in choosing presidential election. ** accused the authorities of appearing to regulate the vote.
President Robert*is stepping down after serving the * two terms. Observers say power's likely to transfer to his chosen successor, the prime minister*.
A major scientific conference in the united states has heard the robots with artificial intelligence could become as clever as humans within 20 years. The inventor and author ,Doc. * told the meeting of American association for the advancement of science that progress in manipular computing would provide what they called the hard-ware for human-level artificial intelligence by the 2020s. He said already more than 20regions of the human brain had been modeled and stimulated.
A Brazilian film about police violence has won the golden bear, the top price of Berlin film festival. The film<the elite score < directed by J portrays the operations of a paramilitary police unit in . the American film maker Thomis* won the best director for there will be blood. The best actor award went to for his performance in the song of spirals as an ostrich farmer who moves to Iran when he loses his job.


People often look at what existed, previous to human creation, as less advanced. We carry the perspective that innovations of the present are, more beneficial, more complex, and more integrated, than designs of the past. While this is often true, could it be possible that something designed by millions of years of evolution could be in fact, more beneficial, more complex, and more integrated with the planet than anything a human could currently design?
Maybe the greatest green innovation is already innovated and integrated with a planet which humans so seamlessly coexist. What's more advanced, the cars in the parking lot, or the tree?
Quotes and inspiration from William McDonough's cradle to cradle design.


The New York Times. December 31, 2014.
Looking for Philadelphia's digital audience.
Old sports stadium has a shot at a happy ending.
Meet the reporter who broke the Philadelphia civil forfeiture story–two years ago.
What a Cleveland news outlet should learn from its flawed Tamir Rice coverage.
The Texas school board isn't as powerful as you think.
10 great novels every urbanist should read.
A literary tour of Detroit.
Will radio save science journalism?
What can Jim Brady's new side do for Philadelphia journalism?
Detroit magnate decides he doesn't want 6,000 blighted Detroit properties after all.
Misleading Jack Schron ad prompts Cleveland Scene to review policy.
A digital transformation for Science.
Author Dave Eggers talks Detroit visits, inspiring kids.
Arson investigators yet to unravel fire at Detroit's First Unitarian Church.
How storytelling heals and strengthens communities.
East Jefferson corridor draws investors despite challenges.
Why are some newspapers abandoning endorsements?
The Tennessean is borrowing reporters from other Gannett papers.
Making the renters vs. homeowners competition a thing of the past.
Beat transfers prompt new labor questions at The Plain Dealer.
Questions of identity rise in Detroit-set Into the Go-Slow.
Columbus Dispatch lets down readers by unpublishing story.
Lisa Lenzo's story collection explores the need for connection.
Creative ways cities are pushing recycling.
This woman has a solution to America's pension problem.
Do 'One Book' programs make a city read?
GOP-backed fake news sites target Dems in congressional races.
How the arts inspire change in Detroit.
Will 'blexting' help with Detroit's blight?
Detroit pensioners voted for self-sacrifice; we should remember that.
For Detroit alt-weekly, rising ambitions and a few questionable decisions.
The nerd who's trying to save Detroit.
Going without water in Detroit.
Living without water in Detroit.
TNR's Scott Walker cover story owed a deep debt to some great local reporting.
Mystery in Detroit: Was pop-up store event successful or not?
The Plain Dealer drops Politifact, but keeps on fact-checking.
Rustbelt Midwest Regional Poetry Slam makes Detroit debut this weekend.
Detroit, Michigan: It's so cool in the D.
6 tips for making it as a freelance writer.
America's most poli-sci friendly reporter delivered a classic — and readers responded.
The demise of urban farming is greatly exaggerated.
A fierce hunt for justice.
Joyce Carol Oates returns to Detroit in latest story collection.
Detroit: A city made of many voices.
How the Detroit Free Press won a Pulitzer in commentary.
Can The Washington Post's national push help support local news?" With Greg Marx.
Who are the fiction writers taking on poverty and inequality today?
Busted is a tale of police corruption–and a newspaper on the edge.
Kalamazoo quietly emerging as a literary hot spot.
Detroit Free Press. March 23, 2014.
Existing restrictions on access to gun records? Not good enough, lawmakers say.
Columbia Journalism Review. March 21, 2014.
The Lone Star Progressive: Annise Parker sells Houston on brass tacks urbanism.
Will a new website deliver on Wisconsin's promises about transparency?
Hannah Arendt: The Last Interview & Other Conversations reviewed by Anna Clark.
Grief and grievances at the Plain Dealer.
You're missing out on great literature.
'This used to be a newsroom.' — The scene at the Cleveland Plain Dealer.
Detroit's false choice: Foundational bailouts could save both art and pensions.
Next City. January 16, 2014.
Finding safer ground through the Affordable Care Act.


Heavy snow spread over much of southern Minnesota on Tuesday February 5, creating major traffic problems for the second day in a row.
A subtle upper-air disturbance associated with a surface low pressure system in Missouri and Illinois, produced waves of moderate to heavy snow from Tuesday morning through Tuesday evening across the southern third of Minnesota. Radars across the region lit up with bright reflectivity echoes, as strong lift in the atmosphere invigorated long and narrow streaks of precipitation.
One particularly intense and persistent band of snow set up in the vicinity of Marshall, Minnesota, where accumulations reached 7-9 inches. The band was so concentrated that areas 25 miles northwest or southeast of town saw only an inch or two.
Another, larger area of snow affected the southeastern third of Minnesota. The highest totals were found from near Mankato, to Waseca and Owatonna, northeastward towards Hastings and Red Wing. In these areas, totals of 6-9 inches were common. The largest reported total in southern Minnesota was at Redwing in Goodhue County, with 9.8 inches. Miesville in Dakota County, and both Northfield and Lonsdale in Rice County, also reported totals in excess of 9 inches.
In the immediate Twin Cities metro area, totals ranged from 3-6 inches, but the heaviest snow was almost perfectly coordinated with the evening commute, bringing the area's delicate transportation system to a near-standstill. The combination of snow, and plenty of leftover ice from the day before, caused vehicles to struggle at intersections and on narrow streets. Some buses were once again were off by multiple departure cycles, and many drivers reported commute times that were 2-4 times longer than normal.
The heavy snow led to some early releases from schools, making it 6 out of 7 days with some level of school disruption in Minnesota. Only Friday, February 1, was free of weather-related cancellations and delays.
Below are snowfall totals as collected by the National Weather Service Office in Chanhassen.


text:
« May Nov »
Disc Jockey helps students support their jocks
October 26, 2016 by rgemmell
By Kim Hernandez
DJ Swell's forehead crinkles in concentration as he prepares his next song to play. The Rowdy Crowd waits in anticipation to hear a familiar beat. A few clicks later, and a new song is blasting through the speakers and heads nod to the rhythm. It is definitely not your typical AUX cord determining these song remixes.
Thanks to our Associated Student Body's efforts to ensure that students enjoy the school events available to them, local disc jockey, DJ Swell, will be at every home football game to help the Rowdy Crowd do what they do best: cheer on our football team.
"He really adds flavor and substance to the high school experience," Senior ASB member Ricky Gutierrez said. "I mean, how many schools can say that they have a DJ at every home football game, you know?"
You can find DJ Swell and his staff at many other school events, but it is the first time that he has been hired to be at every home game of the football season. In addition, he will also be making an appearance at both the Homecoming Pep Rally on Oct. 28, and the Homecoming Dance on Oct. 29.
"[Having DJ Swell] set a really high standard for all the other games, and it gets better each game. If he had not come to the first home game, I don't think the turnout would have been as great as it was," Senior Shannon Rocha said.
Hailing from the city of Las Vegas, DJ Swell is no stranger to sound systems and music. In high school, he was a member of his own school's ASB and helped run the sound for school events. His experience has helped EHS's Rowdy Crowd be spirited for football games.
DJ Swell can't take credit for everything. "I believe spirit begins with the students! If anything, I only add fuel to the fire. I'm so thankful to be a part of your school events," DJ Swell said.
Photo courtesy of DJ Swell (@djswell) Dave Hansen, better known as DJ Swell, prepares to play music for a football game.
Posted in News.	Tagged DJ Swell, news, Rowdy Crowd
Ms. Plantz is growing her way into the EHS community
By;Colin Atlas
Martha Plantz, former substitute teacher and AVID tutor, is now being kept on her toes as a full-time, first-year teacher.
"It is a lot of work, but it is very rewarding," said Plantz.
Before teaching at Escondido High School, she was a college student getting her credential at Cal State San Marcos.
After getting her credential she began substituting at three different high schools: Escondido, Orange Glen and San Pasqual High School.
When she was substituting at other high schools, she was also an AVID tutor here at Escondido High School.
"Escondido felt like home and everyone was very nice here," said Plantz, which is one of the reasons she chose to settle and teach math here.
When it comes to teaching, her students are encouraged to try their best.
"She describes math in a way that everyone understands and has their own perception," said Freshman Jessica Rubalcaba.
Students believe that she shows different ways to solve real world problems when it comes to math and that it is a positive learning environment to be in.
"Ms. Plantz is very calm when it comes to teaching and she puts flavor into her teaching," said Freshman Jabari Washington.
Teaching-wise students agree that it is at a moderate comfortable pace of learning for students and she has a good control over her classroom when it comes to students having the best learning environment.
"She is just a super cool teacher overall," said Washington.
Freshman Jabari Washington is looking over question for the in class assignment during third period.
Posted in News.
New teacher curious about where her career will lead
October 5, 2016 by rgemmell
By:Daniel Gibson
Jessica Jackson, a new Biology and Oceanography teacher at Escondido High School, is excited to be teaching her first year here.
"It's exciting and nice to work with high school students because of their higher thinking," Jackson said.
The students in Jackson's classes have always found a way to make a project very interesting for her because something always goes wrong, but they all just laugh it off and redo the project, making the most fun out of what they have to do, according to Jackson.
Jackson was an assistant teacher for two years and this is her first year of teaching on her own.
Jackson was excited about her first day of teaching.
She said, "I was excited and I was curious as to what the students were like."
Jackson teaches her students how to develop the effort of completing assignments and organization skills.
Students like the assignments and activities in Jackson's class.
Junior Daniel Nunez said, "My favorite assignment is putting all of our work into a packet; it's really fun and she makes it very interesting to do."
Jackson also is liked by all of the students in her classes, according to Nunez.
"She's really fun," Nunez said. "She comes up with a lot of cool and fun games to help us study or learn certain concepts."
"Very interesting class," Junior Sammy Lopez said, "I would highly recommend this teacher, 10/10 best teacher".
STUDENTS WATCH OCEANOGRAPHY VIDEO THEN WORK ON A PACKET ABOUT THE BEGINNING OF THE UNIVERSE
EHS takes on Velazquez Twins
By:Cherish Escobar
Seniors Yzabel Velazquez and Victoria Velazquez are identical twins that have attended Escondido High School since 2013 and have similar interests and classes as well as the same close group of friends.
"The twins aren't easy to tell apart unless you really get to know them. They dress the same and have the same interests, but their personalities are unique," Senior Cameron Deubig said, a close friend to the twins.
People constantly mix up Yzabel and Victoria from each other, although both twins have had a positive impact on our campus by being actively involved in everything from AP classes to varsity volleyball.
Deubig said, "You can't have a favorite twin because they are the same in the way that they are different."
The Velazquez twins are used to being mixed up.
Victoria Velazquez said, "Yeah I'm used to it. I get called Yzabel at least once a day. People always ask me if I get mad but I only pretend to because it's funny to joke about it with people."
Although most can't tell the difference between them, they both are highly involved in our campus and are role models to our students, and the impact of not one, but two individuals that continue to impact EHS with their activities.
Victoria said, "Yzabel and I are similar and different in a lot of ways. One of us is more organized than the other in general."
Although they are both very different from each other, Yzabel Velazquez said, "We're both involved in volleyball, and are managers for boys volleyball."
Their similarities in physical appearance is not the only thing they have in common, as they both actively take part in our community and have made a difference in our school's community.
Seniors Victoria Velazquez and Yzabel Velazquez along with their volleyball team at the end of their volleyball season.
Dear Cougars,
This is your Editor-in-Chief for the magazine "The Cougar" and I'm here to tell you about our journalism class, the goals for our magazine this year and how you can help get involved.
Our class wouldn't exist without the First Amendment since it gives us freedom of speech, press, assembly, religion and petition. The First Amendment gives us the ability to say what we want, print out a magazine and try to make a change in our school and community.
In order to do this, students in our class can write about any issues or topics they want and what can be done to change it. We also highlight issues, events, teachers, students, staff and sports in order to inform the student about what is happening in our school.
Our class is student-run so it's up to our staff to decide what stories they want to write, how they want the magazine to look like and what we want to do next. Our class is not funded by the school so we have raise money ourselves through advertising and sponsorships.
One of our goals in the class is to promote the First Amendment and your rights as students. The other goal is to bring awareness to any issue or events happening in our school, community and world and give a voice to the students.
You can have your voice heard and help our magazine by writing us a letter and send it to room 209. In this letter you can tell us what you want to see in our magazine, any suggestions to help us improve, inform us any issue, event, clubs or people you want to talk about, your thoughts on certain stories, or just your opinion on the magazine overall.
Writing letters to us helps us get involved more with the school, supports our class and helps us improve our magazine. You can also get involved or support us by helping us with advertisement. So if you or someone you know wants to buy an ad, make a donation, or sponsor us, just contact us or ask our advisor or one of the journalism students for an ad contract.
Your 2016-2017 Editor-in- Chief,
Teacher who work and graduated from EHS have special connection to school
By:Miranda Gonsales
Teachers who graduated from Escondido High School and then return to teach new generations feel a special connection to the school, staff and students.
Patricia Stepanek graduated from EHS in 1988, and has been a teacher at EHS for 10 years. She teaches Biology, Honors Biology and Advanced Placement (AP) Biology.
"Those of us who graduated from here feel a sense of loyalty," Stepanek said.
Stepanek enjoys being back at her formal school and says she feels a special connection to the school. Stepanek recalls going to football games and events with her six older siblings since she was 5-years old.
Stepanek teaches biology in the same classroom she took biology in, and said it's neat experience to be back in the same class teaching a subject she enjoys.
Stepanek said, "I think the spirit of being a Cougar has stayed the same."
Michael Jackson is another graduate from EHS from 1987. Jackson has been a teacher at EHS for 19 years. He teaches College and Career Readiness, English 11 and AP Literature and Composition.
"I wanted to be here because this is a special place for me. It's kind of like my home," Jackson said.
Jackson loves being back at EHS, which feels like a second home to him. Jackson explained he feels like working at the school he graduated from is more than just a job, and he enjoys getting up in the morning to go to work.
Freshman Sarai Valdez, who is in Mirna Hernandez's (Class of 2020) PE class , said that teachers who graduated from EHS feel more comfortable on the campus.
Valdez said, "They know what it's like to have Escondido high school experience. I feel like she feels more comfortable here because she's been here longer."


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text:
package org.github.dtsopensource.local.test.dao.dataobject;

public class DtsTestDO {
    private String name;

    private String value;

    public String getName() {
        return name;
    }

    public void setName(String name) {
        this.name = name == null ? null : name.trim();
    }

    public String getValue() {
        return value;
    }

    public void setValue(String value) {
        this.value = value == null ? null : value.trim();
    }
}

redpajama_set_name: RedPajamaGithub


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text:
package uk.fstr.darwingateway.serializers;

import com.google.gson.JsonElement;
import com.google.gson.JsonObject;
import com.google.gson.JsonSerializationContext;
import com.google.gson.JsonSerializer;
import uk.fstr.darwingateway.bindings.PlatformData;

import java.lang.reflect.Type;

/** JSON Serializer for Push Port Platform Data objects created from the XML bindings.
 *
 * @author George Goldberg <george@fasteroute.com>
 */
public class PlatformDataSerializer implements JsonSerializer<PlatformData> {

    @Override
    public JsonElement serialize(PlatformData src, Type typeOfSrc, JsonSerializationContext context) {
        JsonObject object = new JsonObject();

        object.addProperty("number", src.getValue());
        object.addProperty("suppressed", src.isPlatsup());
        object.addProperty("suppressed_by_cis", src.isCisPlatsup());
        object.addProperty("source", src.getPlatsrc());
        object.addProperty("confirmed", src.isConf());

        return object;
    }
}


text:
Home Featured	Films from the Basement: The Killing of a Sacred Deer (2017)
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Films from the Basement: The Killing of a Sacred Deer (2017)
written by Rich Craft July 25, 2018
http://www.thenerdmentality.com/podcast-player/24408/films-basement-the-killing-of-a-sacred-deer-2017.mp3
The Killing of a Sacred Deer (2017)
The Basement crew is back together again to take on the weird surreal thriller The Killing of a Sacred Deer. Steven, a charismatic surgeon, is forced to make an unthinkable sacrifice after his life starts to fall apart when the behavior of a teenage boy he has taken under his wing turns sinister.
This one divides some of the crew who go in-depth with the surrounding plot and themes. Come take a listen and join the crew on their journey into the weird world of Yorgos Lanthimos. Will Alex rant and rave once again about his love for A24?
The Killing of a Sacred Deer is available on Blu-ray and also included with Amazon Prime.
Let us know what you think, or even what films should get the Films from the Basement treatment.
Also, a big basement shout-out to Eric Hutchinson for giving us permission to use a clip of his song "The Basement" as our intro. Be sure to check out his site erichutchinson.com and his various social media hot-spots for all his news and music.
Films from the Basement: The Killing of a Sacred Deer (2017) was last modified: July 25th, 2018 by Rich Craft
A24SuspenseThriller
Rich Craft
I love films, games, books, and have too many hobbies. Proud co-host of the Just the Slips podcast and adequate Rocket League player.
House on Elm Lake (2018) VOD Review
New in Theaters This Week for 07/27/18
Vice Principals Season 2 Giveaway
Lost Treasure of the Grand Canyon (2008) Blu-ray Review
Ballers Season 2 DVD Giveaway!
Nerdwest Podcast – Mass Effect, Alien: Covenant, and VR!


text:
Q: Breakpoint inside thread other than main thread in Visual Studio (Xamarin MessagingCenter) I am sending a Xamarin MessagingCenter message on the main thread. I am able to use the debugger to catch this, but I am not able to use the debugger to catch the message subscriber when it receives and handles the message. I am assuming the handler is not on the main thread, and the debugger is only watching the main thread.
Catching the message before it is sent:

Trying to catch the message when it is received:

The Console.WriteLine statement is executed, but the breakpoint never triggers
Is there a way I can have visual studio watch all threads or something to work around this problem?

redpajama_set_name: RedPajamaStackExchange


The BBC exaggerated a little when in an obituary report they said that Harry Ingram 'invented' contact bridge: but certainly he was a very live influence during its early years. During the 1920's he was a prominent figure in the world of whist drives and a noted expert at auction bridge. With Stan Hughes as his partner, and usually Simmons and Newmark as team-mates, he played innumerable matches to popularise contract in the early 1930's.
The other great figure of those times was Richard Lederer, and in 1934 Lederer and Rose, Ingram and Hughes, joined forces to play Ely and Josephine Culbertson, Albert Morehead and Teddy Lightner, in the second (and last) Schwab Cup match. Over six days' play at the Dorchester Hotel there was very little in it for five days, but both English pairs played badly on the Thursday and lost a lot of points. As Harry remarked at the time, at least three of the English players were doing a full day's work before the evening sessions, while the Americans did not get up till lunchtime.
The most celebrated incident in this match (press coverage doesn't change over the years) was a hand where Ingram, holding a long string of hearts overcalled with a psychic no-trump. Culbertson doubled and Harry removed himself to two clubs, which again was doubled. After some thought Harry bid his real suit, two hearts, and was doubled for one down, a good result. Ely claimed a foul because Ingram had pondered before rescuing himself from two clubs doubled; Harry's answer was that he was considering some further diversionary move, such as a redouble.
In the other room Newark and Simmons had an unopposed run to seven clubs against Phillips and myself.
Harry played three times for Great Britain in the European Championship before the war and in 1936 won a notable victory in the Gold Cup over his old rival. This was a feat, for Lederer had such great players as Kosky and Dodds in support. The Ingram one-club was an effective method, anticipating, as Harry was fond of pointing out, many of the popularised systems of today. Another of his inventions was MOT (middle of three) which he explained in his book How to Win at Bridge. This idea was rediscovered by Eric Crowhurst 30 years later and called MUD.
Also in 1936, the first year of television, Harry appeared on several programmes run by Hubert Phillips at Alexander Palace (sic).
After the war Ingram didn;t play much competitive bridge on a national scale but was very active as a writer, lecturer and cruise director. he and his second wife, Eileen, to whom he was very happily married for 23 years, were always to be seen together in the same corner of the Grand Hotel during events at Eastbourne. i last saw him there, still a handsome figure of man at 84, at the Spring Foursomes. having a personal interest in the matter, i asked him about a hearing aid he was wearing. 'They help a bit', he answered. 'The best thing about them, he added, with a glance at a group of well-known bridge raconteurs nearby, 'is that it's easy to switch them off'. Without a doubt Harry St John Ingram was a man born before his time.