Next weekend (April 6th and 7th) we will be celebrating some special sacraments as part of our parish's preparation for Easter.
On Saturday April 6th at the 5:00 Mass and on Sunday April 7th at 8:30 Mass, we will be having the Communal Anointing of the Sick. Persons, at least 7 years of age, who are seriously ill are invited to be anointed. Also, older persons who are chronically ill because of the effects of aging are welcome to receive this sacrament.


In this role you will be supporting the Order to Cash processes and expand your knowledge and experience in the Customer Success department. You will have the responsibility to keep the stock levels in sync with our Logistic Service Providers. Therefore you will need to develop and maintain good relationships with the local Logistic Service Providers (LSP) and our internal LSP managers.
You will have room to apply your analytical capabilities to investigate, find root causes of inventory discrepancies and propose alternative solutions.
You also will get the opportunities to expose yourself cross-functionally by representing the department as an subject matter expert in various process improvement meetings.
Being an experienced SAP user and combining your advanced excel skills with your analytical skills will be the perfect match to successfully perform this function.
In line with the EU Supply Chain OE/LEAN roadmap, you will also identify & initiate process improvements.
If you are accurate, have attention to detail and you like to work on process and system improvements you will be valuable to joining and strengthen our team.
Monitors stock comparison and resolves stock related issues on a daily basis and on a monthly basis as part of SOX.
Coordinates and conducts physical stock counts, executes stock reconciliation, and completes related documentation.
Develops and maintains good relationship with LSPs.


text:
Q: Cloud code causes "Tried to save an object with a pointer to a new, unsaved object" when saving pointers In my app, I have users and posts, and I am trying to instantiate my Activity class which has pointers to user and post objects. Here is my code:
var Activity = Parse.Object.extend("Activity");
var User = Parse.Object.extend("_User");
var Post = Parse.Object.extend("Posts");

var activityHandler = function(request, response){
    //toUser is the objectId of the User not the object itself.
    var toUserId = request.toUser;
    var fromUserId = request.fromUser;
    var postId = request.post;
    var arg = request.argument;

    var toUser = new User();
    toUser.set("objectId",toUserId);
    var fromUser = new User();
    fromUser.set("objectId",fromUserId);
    var post = new Post();
    post.set("objectId",postId);

    var activity = new Activity();
    activity.set("activityFrom", fromUser);
    activity.set("activityTo", toUser);
    activity.set("argument", arg);
    activity.set("post", post);
    activity.save(null, {
        useMasterKey: true,

            success: function(o){
        console.log("activity logged successfully");
        response.success();
            },
            error: function(err){
        console.log(err);
            },
        }
    );
};

Parse.Cloud.define("createActivity", activityHandler);

The code is self-explanatory, but just to summarize, the client sends the appropriate user and post IDs, and the cloud function should instantiate a new Activity object, with pointers to the users and post. However, when I try to save, I'm getting:
{"code":141,"error":"Uncaught Tried to save an object with a pointer to a new, unsaved object."}
The problem is that, the object IDs sent to the function are completely valid, already-existing objects in the database. ACL is also not an issue as I'm on the master key.
What am I doing wrong?

A: It was my bad.
There were multiple problems with my code.

*

*I was using object.set("objectId", id); syntax, which actually should be object.id = id. I'm not sure if it is necessary, maybe it would work without that change too, but I've read everywhere that it's a bad practice.

*I wasn't getting the request parameters correctly. I was using request.param1 instead of request.params.param1, and the parameter variable was undefined. I haven't checked if it was undefined or not for a long time, as the error message wasn't really helpful about parameter being undefined, from my perspective back then. (now it makes sense, no ID, and it automatically tries to create a new object)
I've corrected them and it does save correctly now.

A: This also happens when you forget to call the method:
response.success(object);

redpajama_set_name: RedPajamaStackExchange


text:
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Get L.A.'d Tonight with Rockstar Games' Mystery Epic
Monday, June 13, 2011 by Randall Woo Leave a comment
From the same company that brought you the Grand Theft Auto series comes L.A. Noire. It's a homage to film noir; think Dashiell Hammet's The Maltese Falcon, or even the 2005 film Sin City. The game is set in 1940's Los Angeles and you play as Cole Phelps (played by Mad Men's Aaron Staton), an up and coming detective with a dark past. You follow his career as he works his way up through the ranks of the police department.
One of the greatest assets of the game is the recreation of 1940's Los Angeles. It may sound cliché, but the city itself is a character. There are several famous landmarks and neighborhoods that are represented. I'm a former Los Angeles resident myself, and as I drove throughout the city in-game, I could sense which neighborhood was which. From the dress of the characters, to the songs and programs on the car radio, to the cars themselves, you can tell that the game designers went to great lengths to create this historical representation of L.A. They even include real cases like the Black Dahlia Murder as a backdrop for some of the cases in the game.
Another key feature of the game is the facial motion capture system. The game developers had real life actors act their parts and implemented their performance onto their character models. This technology is especially prominent in the witness questioning part in the game, where you have to discern whether someone is honest, lying, or maybe withholding information from you. You have to study their face and look for telltale signs, such as shifting eyes, hard swallows, smirks or other facial quirks.
Just a small glimpse of the rigorous facial capture process.
The gameplay tends to lend itself to the following formula: investigate crime scenes, find evidence, interview witnesses, and in some cases, interrogate suspects. The game is divided into cases, and you'll find yourself moving through four different "desks" throughout the game: homicide, traffic, vice and arson. Despite having a different backdrop, these cases play out more or less the same, and usually involves a dead body or two. You drive from location to location, searching for evidence and interviewing suspects.
There are also side missions called "street crimes" that arise throughout the course of the game. These missions tend to be much more action-oriented. They can consist of fistfights, gunfights, car chases, and more. These missions provide a nice change from the slower pacing in the investigative part of the game.
The comparisons to GTA are inevitable, however, this is not a sandbox game. There's little incentive to explore the world outside of the locations required for the cases. You are forever stuck playing the role of good cop. Your weapon is always holstered, and you cannot draw it unless you are in a designated gunfight sequence. You can't even change weapons or ammo on the fly. You always start with a handgun unless you pick up a different one from someone you shot. This resets every time you enter the gunfight sequence. You have to be a good driver, avoiding all other cars and pedestrians. Any damage incurred is tallied at your end of the case report. What's frustrating is that it feels like an open world game like GTA, but it's mostly a facade. This game is unflinchingly linear.
You'll use a mix of hard evidence, careful observations, and threats to squeeze confessions during the interrogation scenes.
I found it difficult at times to invest myself emotionally in the game. During my playthrough I felt that the story unfolded a little too linearly for my liking. The first time I encountered a hostage situation I was gripped. I really felt the potential consequences for my actions. However, this was quickly lost as I soon found that there was little to no room for failure. I found myself not caring about what happened because certain situations can be replayed if they are not completed satisfactorily. Either you complete the event as scripted, or the game does not continue. This isn't always the case however, as it is possible to miss clues or falsely accuse people.
The controls can be a bit frustrating at times. Rotating and moving your character can be a cumbersome affair as he awkwardly pivots and turns about. Gunfights can be especially irritating due to the cover system that is implemented. It's especially apparent in tight spaces, where I found my character gluing himself to the wrong wall, and as a result, exposing himself to a barrage of bullets.
The city of 1947 Los Angeles itself is one of the biggest characters in the game..
The historical setting is a crucial element of the story, and reminded me a bit of Mafia 2. Both games are set in the aftermath of World War 2. In Mafia 2, Vito turns to a life of crime, while in L.A. Noire Cole does the opposite. One of the key plot points is Cole Phelps the war hero, struggling to come to terms with Cole Phelps, the rapidly ascending crime fighter. Flashback scenes are strewn throughout the game, and they help set the backdrop for the narrative, essentially filling in details for the gamer. These include scenes from the war, as well as events that unfold throughout the game. One qualm I had about the flashbacks were that they are usually told from an omniscient third-person perspective. I would have liked these parts to have been more seamlessly woven into the narrative, but all the different threads wrap up nicely in the end.
Overall, despite its flaws, L.A. Noire is a really solid game. I have to give credit to the developers for trying something new. There really isn't another game out there that's like it. There is replay value to be found in the game, but the real meat of the game is in the main story.
-Randall Woo
Filed under Mystery/Thriller, Playstation 3, Video Games, Xbox 360 Tagged with 360, aaron staton, cole phelps, grand theft auto, l.a. noire, la noire, los angeles, mystery, ps3, red dead redemption, rockstar, thriller, wrecked, wrecked reviews
About Randall Woo
Me, fail English? That's unpossible.
Sorry for the spam, folks. Please disregard and go kick some ass. 6 years ago
Happy Saturday! Go Giants! wreckedreviews.com/2012/10/06/jus… 7 years ago
Download "Leathers", a brand new track off Deftones' upcoming album, "Koi No Yokan" here: deftones.com/main/ 7 years ago
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Batman Concludes with The Dark Knight Rises! Check out Darren's review: wp.me/p1iCBb-1hH 7 years ago
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redpajama_set_name: RedPajamaCommonCrawl


text:
require 'test_helper'

module Elasticsearch
  module Test
    class APITest < ::Test::Unit::TestCase

      context "The API module" do

        should "access the settings" do
          assert_not_nil Elasticsearch::API.settings
        end

        should "allow to set settings" do
          assert_nothing_raised { Elasticsearch::API.settings[:foo] = 'bar' }
          assert_equal 'bar', Elasticsearch::API.settings[:foo]
        end

      end

    end
  end
end

redpajama_set_name: RedPajamaGithub


Subtle ribbing adds soft texture to our dolman sleeve sweater topped with a collarbone-grazing neckline.
Hand wash in cold water with mild detergent. Wash separately. Do not bleach. Reshape when wet. Hang to dry.
Dolman Sleeve Knit Sweater is rated 4.5 out of 5 by 8.
Rated 2 out of 5 by Pikachiu132 from Love the style, poor quality I love this style. I bought 2 in different colours. But there's something about this purple one that is disappointing. Ive worn the sweater for one day, and the string is already pulling and now makes this brand new sweater look 10 yrs old. I didn't buy the ones in the store for the same reason and ordered online to home. The grey didn't do this for some reason or at least wasn't noticable. For the price I paid I'm disappointed in the quality and durability.
Rated 5 out of 5 by Smart casual from Practical sweater My new casual Friday go to. Warm and comfortable.
Rated 4 out of 5 by Fashion is my game from A sweater with flair! This black sweater pairs well with pants and skirts. The dolman sleeves are comfortable and stylish. Top it off with a long necklace to finish off your look.
Rated 5 out of 5 by Versatile from So chic and contemporary Fabric flows with the body making it look elegant can dress it up for evening and also wear to work!
Rated 5 out of 5 by Fern C from Love this style. Clean lines and comfortable I absolutely love this sweater. It's simple, elegant and comfortable.
Rated 5 out of 5 by Sue W from Love it! Perfect sweater as it can be worn with jeans or with dress pants. Very versatile.


text:
Mr. Martin Scheinin, Special Rapporteur on counter-terrorism - Press Conference
26 Oct 2010 - Mr. Martin Scheinin, Special Rapporteur on counter-terrorism - Press Conference
Mr. Manfred Novak, UN Special Rapporteur on torture - Press Conference
English 1 Nov 2010
UN Special Rapporteur on racism and xenophobia, Mr. Githu Muigai - Press...
The Special Rapporteur on Freedom of Religion or Belief, Mr. Heiner Bielefeld...
Olivier De Schutter, Special Rapporteur on the right to food - Press Conference
Heiner Bielefeldt, Special Rapporteur on freedom of religion or belief - Press...
Daily Noon Press Briefings
Media Stakeouts
Geneva Press Briefings
Español 27 Sep 2019
Delcy Rodríguez (Venezuela) - Press Conference (27 September…
President of the Republic of Colombia, Ministry of Health and…
Opening of the 74th session of the General Assembly - Press Conference…
María Fernanda Espinosa (General Assembly President) on her work…
Permanent Mission of Venezuela - Press Conference (Geneva, 1…
Español 15 Aug 2019
Press Conference: Ambassador Ndong Mba, Permanent Representative…
Español 24 Apr 2019
The Situation in the Middle East - Security Council, 8515th meeting…
María Fernanda Espinosa (General Assembly President ) & Female…
António Guterres (United Nations Secretary-General) on his priorities…
Español 2 Jan 2019
José Singer (Special Envoy of the Dominican Republic to the United…
Español 21 Nov 2018
María Fernanda Espinosa (President of the General Assembly) on…
UN Chief on 73rd Session of the General Assembly - Press Conference…


Differential equations considered in terms of exterior differential forms, as did É. Cartan, distinguish a differential ideal in the supercommutative superalgebra of differential forms, i.e., an affine supervariety. Therefore, each differential equation has a supersymmetry (perhaps trivial). Which superymmetries of systems of classical differential equations are not yet found? We also consider the question of why criteria of the formal integrability of differential equations are currently never used in practice.
Prepared from an English manuscript submitted by the author; for the Russian version, see Teoreticheskaya i Matematicheskaya Fizika, Vol. 198, No. 2, pp. 309–325, February, 2019.


San Juan Island Hopping – Let's Go Biking! San Juan Island Hopping – Let's Go Biking!
The San Juan Islands are perfect for island hopping and traveling by bike. What's better than loading up the panniers and heading out on a car-less journey to many islands linked by ferries. There's lots to explore and the riding is quite easy on country roads, with Mount Baker views, beaches, coves and rolling farmlands — the San Juans have it all.
You can park at either end and ride aboard the ferry for a summer biking get-a-way.
is one of the largest islands and there are many routes and loops to explore. Traffic is minimal and the roads are good for biking. There are dozens of hotels and B+B's to choose from. Friday Harbour is a quaint town with lots of restaurants and shops. Roche Harbour has some accommodation and a good restaurant in the old hotel. Depending on your skill and distance level you can ride all day long or choose a shorter ride each day. San Juan Island Trails Committee has a Great Map.
1 – Around the Island – the longest of the loops, can be done in a day or stay at Friday or Roche Harbour for one night and make it a two day ride.
a picnic lunch, lock up the bikes and explore the trails. More information here. Link to more American Camp Ride information and map.
Island as they often feed and travel along this shore.
farm fields, daisies, and sea views.
there. We had dinner at The Bay Cafe in Fisherman's Cove. The link to their website also lists nearby accommodation. Link to more Lopez Island cycling information and map.
ORCAS ISLAND – is the hilliest of the islands and with more car traffic. Eastsound is the main village on the island with lots of shops, restaurants and accommodations. Olga Bay is worth a visit by boat or bike.
SHAW ISLAND – we took the early ferry to Shaw and did a loop around the island and then picked up a later ferry and headed to the next island. Just near the ferry terminal is the Shaw Island General Store – a good place to visit.
GUEMES – this small island is close to Anacortes. It's flat and easy and a quick day trip from Anacortes.
Day 1 – park at the Anecortes ferry lot and roll the bikes on board.
– ride out to Lime Kiln Park, Lavender fields and island loop.
Day 4 – Lopez – stayed at MacKaye Harbour house and did the Lopez Island Loop with a hike at Iceberg Point.
Day5 – Lopez – Board ferry for Anacortes then ride to Guemes Island ferry.
Got a picnic lunch at Anderson's General Store, circled the island, lunched at the north side then back to cars and drove home.


Appeal from the Circuit Court of St. Clair County.No. 13-CF-882 Honorable Robert B. Haida, Judge, presiding.
JUSTICE GOLDENHERSH delivered the judgment of the court, with opinion. Presiding Justice Barberis and Justice Chapman concurred in the judgment and opinion.
¶ 1 This appeal arises from an order of the circuit court of St. Clair County that denied defendant's motion to withdraw plea of guilty to the offense of armed robbery (720 ILCS 5/18-2(a)(1) (West 2012)). In his motion, defendant argued his plea was not knowing and voluntary because his plea counsel was ineffective. For the following reasons, we reverse the circuit court's order denying defendant's motion to withdraw plea of guilty, vacate defendant's conviction and sentence, and remand this cause with directions to allow defendant to plead anew.
¶ 3 Defendant, Gabriel Boyd, pled guilty to a single count of armed robbery, a Class X felony, on May 15, 2014, pursuant to a fully negotiated plea agreement in which defendant agreed to a sentence of 18 years in the Illinois Department of Corrections, with 3 years of mandatory supervised release. See 720 ILCS 5/18-2(a)(1) (West 2012). In exchange for defendant's guilty plea, the St. Clair County State's Attorney's Office (State) dismissed three other counts against him. After admonishing defendant and finding a factual basis for the plea, the court concluded there were no improper promises or inducements that caused defendant to plead guilty and accepted the plea as voluntary.
¶ 4 Defendant filed a pro se motion to reconsider sentence on June 2, 2014, alleging that the sentence imposed was excessive and his plea counsel was ineffective. Because defendant's motion alleged ineffective assistance of counsel and defendant had already entered a guilty plea, the trial court construed defendant's motion as a motion to withdraw the guilty plea and appointed the public defender to represent defendant in all postplea proceedings. The appointed public defender filed a motion to withdraw plea of guilty on September 26, 2014, asserting (1) defendant's plea of guilty was not voluntary because defendant's plea counsel was ineffective, (2) defendant did not fully understand the potential sentence he faced, and (3) defendant did not understand the nature of the charges against him. The motion to withdraw plea of guilty further asserted defendant had a defense worthy of consideration.
¶ 5 A hearing on defendant's motion was held on October 1, 2014. At the hearing, defendant testified his plea counsel informed him that in exchange for a plea of guilty, defendant may be eligible to enter certain programs in prison which would allow him to receive credit for good time against his sentence. However, after he arrived at the Department of Corrections, defendant testified he discovered he was ineligible to receive any type of good time credit because his case involved a Class X felony. Defendant testified that if he had known he was ineligible to receive good time credit prior to pleading guilty, it would have "changed [his] mind on pleading guilty." On cross-examination, defendant testified the trial judge asked him a number of questions prior to defendant pleading guilty, including whether defendant had been promised anything other than the plea negotiations and whether anyone threatened him. Defendant testified he had not been promised anything and was not threatened.
¶ 6 Plea counsel also testified at the hearing. He testified that he and defendant had a number of conversations about the nature of the charges brought against defendant and the State's plea offers. Plea counsel testified he did not promise defendant that he would be eligible for good time credit, meritorious service credit, or credit obtained through programs in the Department of Corrections. He also testified he spoke with defendant about the potential for programs in the Department of Corrections but denied ever telling defendant he would be guaranteed acceptance into those programs or that the programs would reduce defendant's time. He testified that he "absolutely" never made any promises or used threats or coercion to convince defendant to plead guilty and that defendant knew trial was always an option up until the day he pled guilty.
¶ 7 On cross-examination, plea counsel testified that when talking to defendant about the amount of time he would have to serve, he told defendant his sentence may be cut in half if he received day for day good time credit. He testified he also discussed that defendant may receive an initial six-month credit. He further testified that he talked to defendant in general regarding educational programs that may result in a reduction of time, but nothing specific as to the amount of time or whether there would actually be a reduction of time. In rebuttal, defendant testified, "It was kind of absolutely a promise that I would be able to get into some programs and I would be able to get some good time if I completed the programs."


text:
John Alanis.com
« October 03, 2006 | Main | October 05, 2006 »
What the BIG SECRET to attraction?
Dear friends and subscribers,
What if I were to tell you there was one BIG SECRET to creating attraction with any woman you want? Further, what if I were to tell you that any can put this secret to use immediately, regardless of your looks, age or income to attract the women--or woman--you truly desire? How interested would you be?
Here's the truth: there IS one big secret to attraction, and it's called "personal authority." Most men are confused by this, having been deliberately been trained to be wusses and nice guys by society, been trained to think that authority is a bad thing.
It's not... IF you use it correctly. Most men don't because they don't know how. But women crave a man with personal authority, they dream about such a man. And you can be that man, if you understand a few simple secrets, things society at large does not want you to know. But I do--and I have condensed these secrets into an easy to use system you can put to work for you immediately. For details, go to http://www.johnalanis.com/authority.htm right now, before I decide to remove this website for good.
On with the fun...
-John Alanis
"The King of Let 'em Come to You"
PS Personal authority in a man is like a narcotic to women... they can't resist. That's the good news. The bad news is, if you don't give it to them, they'll leave and find a man who will. Don't be the man they're leaving, be the man they run to. Go to http://www.johnalanis.com/authority.htm right now.
What should you tell her when she asks...?
A lot of guys feel guilty when they go out in the dating scene because they don't know what to tell a woman when they're dating more than one. What they don't know is, most women who are "just dating" actually expect that--and welcome it--because they're sick and tired of guys who think they're "the one" after one or two meetings.
Still, though, it is a good question--how should you deal with it when a woman asks you? Here's the email that sparked it, and my answer below.
***Advertisement***
A whole new approach to dating, women, and relationships that allows me to choose my own relationships with women, anytime, anyplace, anywhere, devoid of all heartbreak or misery, and I'm convinced any man can copy what I'm doing, no matter your looks, age, or income. Why would any sane man reveal these secrets if they were true? To discover the answer go to http://www.johnalanis.com/ultimate_system.htm right now.
I do all right with women, but could always do better. What I am saying is that I am no where near desperate like many who contact you.
My question has to do with how to handle success. What do you tell women about other women if you date more than one? I don't wish to be a boor and brag about other women. And I am not whether dropping hints about other women will be a turn-off or turn on. Will women think "he has plenty of women - he must be hot" or "he is a real "player" I had better be careful?"
But I invariably get asked by women "how was your weekend?" I always wonder if I should say "I had dates with someone else besides you on Friday and Saturday" or something vague like "OK - but nothing big." I do not want to lie and it is possible a woman will find out about the other dates anyway and think I am being dishonest.
Another John
JA: Thanks for the email, John. Actually, you'd be surprised by the lack of desperation by most guys on my list. Most are already on the path to success, and just want to discover how to become more so.
Women intuitively know when you're a guy who's good with women, and for the most part, assume you're available to others, up until the point you and her decided to see only each other. There's no reason to brag or boast about what you do, or even mention it. If you do so as an effort to make her jealous, it will back fire because you're relying on external circumstances to create attraction, not internally generated behavior. But you shouldn't hide it either.
If you're asked, be truthful--but in a fun, naughty manner--"yep, I had a few naughty girls compete for my attention this weekend--they did OK. Room for improvement, though." Then just smile and move on. If you're a guy who's good with women, you're just describing your reality, much as other guys would describe going to a movie. It's just no big deal to you. Don't boast about it, don't hide it, just treat it as a normal circumstance, which it should be. The truth is, she's probably seeing other guys too. When it's time to date, it's time to date, and when it's time to commit, it's time to commit. It's not a good idea to hide anything in either circumstance.
On with the fun....
PS Ready to step up to the Big Leagues and lead a lifetime of power, success, and choice with women? Go to http://www.johnalanis.com/ultimate_system.htm right now.


text:
Runs & Races
Your Better Running Self
Web Membership
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Home > The Scene
Gabriela DeBues-Stafford to join Bowerman Track Club
Six-time Canadian record-holder Gabriela DeBues-Stafford is officially a Bowerman babe
Madeleine Kelly July 22, 2020
Gabriela DeBues-Stafford is coming off the year of her life. In 2019, she set broke eight Canadian records and moved across the world to Glasgow, Scotland, to pursue her dream of becoming one of the best runners in the world. During her year there, she ticked almost every box she had for herself performance-wise, including a sixth-place finish in the world championship 1,500m final. But personally, she missed home. On Wednesday, she announced that when it's safe to do so, she'll be joining the Bowerman Track Club based in Portland, Oregon.
https://www.instagram.com/p/B_vgm8mHz6G/
RELATED: Gabriela DeBues-Stafford smashes her own Canadian record in insanely fast Worlds 1,500m final
The Toronto native has been stationed out of her childhood home for most of COVID-19 after returning to Canada from Scotland on March 25. Since then, DeBues-Stafford has had younger sister and Canadian 1,000m U23 record-holder Lucia Stafford to train with on her old stomping grounds. DeBues-Stafford says when she left Scotland in March, she intended to return, but after spending a month in Toronto, it became clear that she and her husband needed a change. "There were some question marks at the point about how sustainable it was for me and my husband to stay in Scotland. We were still committed to going back when we left, but the longer we were in Toronto, it became clear that we needed something different."
https://www.instagram.com/p/B–wME2nJFc/
DeBues-Stafford settled on Bowerman shortly thereafter and began the transition to so-called "Jerry Workouts," named after the team's head coach Jerry Schumacher. "It was really exciting that Jerry and the team were willing to work with me. Then there's the draw of Shalane [Flanagan] as well, and most importantly, being closer to home. I didn't want an ocean to separate me from my family anymore."
The world championship finalist realized that she'd felt a little isolated in Scotland. "I want to participate more actively in the Canadian running community and I want to be able to see my family more often. Those are things I really missed and can have more easily now. I think, longterm, Bowerman will be a better fit." On top of those personal reasons, DeBues-Stafford says she sees the Bowerman group as highly diverse in their talents. "There's a lot of success in a range of distances from the 800m through to the marathon. Looking at longevity, I'll want to play around with longer distances. Jerry's program is versatile, so I can work with different runners depending on what distance I'm attempting."
https://www.instagram.com/p/B3VVL5Rnw6Q/
DeBues-Stafford says the transition has been smooth so far, but that she won't take the real plunge and move to the U.S. until the fall. "The workouts are going well, the mileage is a bit higher in the Bowerman group than I'm used to, but we're increasing it slowly. For now, I'm still in Canada while we sort out visas and wait for the borders to open. The process of moving is underway, but it's a bit of a moving target right now. I'm hoping for September."
RELATED: Moh Ahmed wins again, sets 1,500m PB at Bowerman Track Club meet
Categories: The Scene Tags: Bowerman Babes, bowerman TC, Featured, gabriela stafford
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text:
Q: Android - cannot cast android.widget.RadioGroup to android.widget.RadioButton This question is similar to this one but this question is little bit different.
I am creating 15 RadioGroups and 4 radio buttons inside each group using for loop.
for(int i=0; i<15; i++) {
      RadioGroup radioGroup = new RadioGroup(getActivity());
      radioGroup.setOrientation(RadioGroup.HORIZONTAL);
      LinearLayout.LayoutParams lp = new LinearLayout.LayoutParams(LinearLayout.LayoutParams.WRAP_CONTENT, LinearLayout.LayoutParams.WRAP_CONTENT, 1.0f);
      radioGroup.setLayoutParams(lp);
      radioGroup.setId(i+1);

      for(int j=0; j<4; j++) {
            RadioButton radioButton = new RadioButton(getActivity());
            radioGroup.addView(radioButton);
        }

      radioGroup.setOnCheckedChangeListener(radioListener);

}

And this is radio listener code:
final RadioGroup.OnCheckedChangeListener radioListener = new RadioGroup.OnCheckedChangeListener() {
        @Override
        public void onCheckedChanged(RadioGroup radioGroup, int checkedId) {
            RadioButton radio = (RadioButton) rootView.findViewById(checkedId);
            String selectedValue = radio.getText().toString();

        }
    };

The above code is responsible for the exception. According to Android developers, checkedId is

the unique identifier of the newly checked radio button

The problem with this code is that it works sometimes and doesn't works other times. There are a total of 15 radiogroups so if I select radiobuttons from 2nd to 15th group, it will show no error and everything will execute perfectly but when I select the 1st radio button of the very first radio group, it throws the exception - cannot cast android.widget.radiogroup to android.widget.radiobutton


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text:
Questa lista delle carestie comprende, in ordine cronologico, le principali calamità che portarono un gran numero di persone, di ogni era o continente, a morire d'inedia o per le malattie conseguenti alla denutrizione.

V secolo a.C.
 440 a.C. Carestia nell'Antica Roma.

V secolo d.C.
 Carestia nell'Europa occidentale associata alla caduta di Roma e al sacco dei visigoti di Alarico I.

X secolo
 974-975 Un inverno rigidissimo e una primavera tardiva provocarono una carestia, che uccise un terzo della popolazione franca e la metà dei parigini.

XIV secolo
Ebbe inizio la "piccola era glaciale", che avrebbe reso più frequenti le carestie nei secoli seguenti.
 1315-1317 La Grande carestia in Europa. Ulteriori carestie avrebbero colpito nel corso del secolo un'Europa la cui popolazione fu decimata dalla peste nera.
 1333-1337 Carestia in Cina.

XV secolo
 1437-1440 Negli anni 1430 nell'Europa nord-occidentale, vi furono una serie di anomalie climatiche e si susseguirono inverni molto lunghi e freddi ed estati calde e piovose. Come conseguenza, la carestia degli anni 1437-1440 portò alla morte centinaia di migliaia di persone.

XVI secolo
 1567-1570 Carestia ad Harar in Etiopia, insieme alla peste. Nur ibn Mujahid, emiro di Harar, morì.
 1570 Una dura carestia colpì Milano, diocesi di San Carlo Borromeo.
 anni 1590 Carestie in Europa. A seguito dell'importante servizio reso a Roma durante la carestia del 1590, papa Gregorio XIV elevò la Congregazione di san Camillo de Lellis a Ordine dei Chierici Regolari Ministri degli Infermi.

XVII secolo
 1601-1603 carestia in Russia come conseguenza dell'eruzione di un vulcano in Perù
 1618-1648 Carestie in Europa causate dalla Guerra dei trent'anni.
 1630-1631 Carestie in India.
 1696-1697 Carestia in Finlandia.

XVIII secolo
 1709 L'Ondata di freddo dell'inverno 1709 provocò una grave carestia (grande famine) di cui si hanno dati precisi per la Francia. Secondo lo storico Emmanuel Le Roy Ladurie questa carestia avrebbe causato la morte di circa 600 mila francesi, circa il 3% della popolazione dell'epoca, nonché la crisi finanziaria del 1709.
 1740-1741 La grande carestia in Irlanda.
1763-1764 Carestia in Italia centrale e meridionale
 1770 Carestia in Bengala.
 1783 Carestia in Islanda causata da eruzioni vulcaniche.

XIX secolo
 1816-1817 Carestia in Europa e America settentrionale (anno senza estate).
 anni 1830 Carestia dell'era Tenpo in Giappone.
 1845-1849 Carestia delle patate in Irlanda e "rivoluzione delle patate" (Kartoffelrevolution) a Berlino nel 1847 .
 1846-1857 Carestia delle patate in Scozia.
 1850 Fine della "piccola era glaciale".
 1866 Carestia in India (Bengala e Orissa).
 1866-1868 Carestia in Finlandia.
 1876-1879 Carestie in India, Cina, Brasile, Nordafrica (e altre nazioni).
 1879 Carestia in Irlanda, la cosiddetta "mini-carestia".
 1888-1892 La grande carestia d'Etiopia Le condizioni peggiorarono quando si sparse il contagio del colera (1889-92) e una grave epidemia di vaiolo (1889-90).
 1896-1897 Carestia nella Cina settentrionale.
 1896-1902 Carestia in India.

XX secolo
 1914-1918 Carestia sulle montagne del Libano durante la prima guerra mondiale.
 1919-1920 Carestia in Polonia a causa della guerra.
 1921-1923 Carestia in Russia a seguito di sei anni e mezzo di guerre e disordini (Prima guerra mondiale, Rivoluzione russa, Guerra civile russa).
 1928-1929 Carestia nella Cina settentrionale.
 1933 Holodomor in Ucraina.
 1941-1942 Carestia in Grecia per l'occupazione nazista.
 1943-1944 Carestia in Bengala.
 1944 Carestia nei Paesi Bassi durante la seconda guerra mondiale.
 1945 Carestia in Vietnam.
 1959-1961 Grande carestia cinese.
 1968-1972 Siccità del Sahel in Africa.
 1973 Carestia etiope; l'incapacità del governo di gestire la crisi provocò la caduta dal potere dell'imperatore Hailé Selassié e della giunta Derg.
 1974 Carestia del Bangladesh.
 1984-1985 Carestia in Etiopia.
 1997 Carestia in Corea del Nord.
 1998 Una Carestia nel Sudan causata dalla guerra e dalla siccità.
 1998 Carestia nello Zimbabwe

Note

Altri progetti

Carestie

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Ebb And Flow: A Home Inspired ..
Bill Henson: The Gloaming
Luchetti Krelle Add A Little "..
by Stephen Todd
The glimmer, the glisten, the glamour*… Life imitates art in the home of Australia's most corporeal artist, Bill Henson.
Vienna, the summer of 1977, a young man is seated on a dark charcoal velvet couch in an upper room of the Kunsthistorisches Museum staring at Titian's Nymph and Shepherd painted some 400 years before. He's been there every day for a week now, mesmerised. Sunlight gently dripping from skylights overhead, he's absorbed in the oscillations of luminosity as clouds pass over the sun. Outside, across the topiary of the Maria-Theresien Platz, atop the Natural History Museum is a statue of Captain James Cook, erected in 1771 as a symbol of a new age of discovery. Our young man is in Vienna on a very different kind of quest.
"The room was breathing, all the information would slide away into the gloom, a dim obscurity. Then the sun would come out and all of a sudden you'd see this opalescent flesh start to sparkle." The young man was Bill Henson, the Titian his obsession.
Forty years later we're seated upstairs in Henson's grotto of a loft in the inner Melbourne suburb of Northcote. Over his shoulder an English pastoral painting in the style of Turner emanates from a wall painted a velvety brown-black, the shade Bill suggests galleries employ to best offset his work. He's wearing what appears to be the same pale green corduroy trousers and grey sweater he was wearing when I visited him a week before to begin talking about this story. "I think the hole's bigger in this one," he muses, tugging at the left sleeve and confessing he always buys the same thing. A knitted tea cosy, a snatch of spindly japonica, disparate trinkets; the setting is at once humble and sumptuous, a compelling paradox I've come to recognise as very Henson.
Next door, his library is not so much lined with books as it is brimful of them. A gaggle of Anglepoise lamps crane over volumes stacked in the centre of the room. The mix of natural and incandescent light creates an amber glow, a heady honey hue in which everyone and thing looks pleasing. The lamps have not been moved since my previous visit, but the books laid open at various points around the room have changed. It's easy to imagine Bill Henson wiling his days away, swooning from one first edition to the next. The vision would be fey if the reality weren't so intense.
"In that corner over there," he says, indicating a black swivel chair beneath a west-facing window where the vigour of afternoon daylight creates greatest tension, "that's where I sit with my feet on the desk and look at my contact proof sheets. I have music going sometimes, and I have a white Chinagraph pencil and I have my magnifying glass and I go back and forth over them and I might do that for a day, a week, six months or maybe a year. I will have a wonderful time trying to sift out the shots I think are going to work when I blow them up."
The blowing up (not "enlarging", Henson's is a frank lexicon) happens downstairs in what would best be described as his atelier – if an atelier can be kitted out with rare books, museum-grade antiquities, and dozens if not hundreds of large format photographs sitting one behind the other on robust timber easels. Hanging from an iron I-beam, two wooden gymnast rings hover on leather straps above a satiny, poured concrete floor. Bill Henson is one of Australia's greatest living artists, certainly our most cerebral – and perhaps, somewhat surprisingly, our most corporeal.
For most of his adult life, Bill's been a runner, clocking up at least ten kilometres a day "as a form of relaxed meditation". For the past decade he's worked with a personal trainer by the name of Ozgur three days a week, two hours a day. Plus the high-speed, twenty-kilometre bike ride from Northcote to the gym in South Melbourne and back. "The brain is in the body, and when working out it's as if what Nietzsche referred to as the great intelligence of the body takes over. You switch off some intellectualised aspect of life for a time."
ST: So you have a body of steel?
BH: I don't know, it's got all this old skin on it.
ST: When you're photographing, do you reach the same sort of intensity as you attain in your physical training?
BH: It's very intense in that it's a big deal which means that I'm quite anxious. There's a high level of anxiety mixed with anticipation for which the Germans have a perfect word, erwartung. I'm not necessarily outwardly stressed, it's just that it's almost impossible for me to pick up a camera. I pick up a camera when I have absolutely no choice. It's not a pastime where I play around.
That pilgrimage to Vienna in his early twenties happened shortly after Henson first exhibited his work, part of a group show. He'd been enrolled in the Photography department of the Prahran College of Advanced Education under the tutelage of noted portrait photographer, Athol Shmith. While Shmith and fellow Prahran College director John Cato recognised Henson's very evident talent, his repeated absenteeism and failure to complete assignments led them to recommend he ditch academia. "I'd rock up after not being there for three of four months and they'd just shake their heads and say, We love the pictures you're making but there's no need for you to be here." He didn't need to be told twice.
Released into the wild, the artist as a young man began taking portraits. Of schoolgirls, of passersby, of budding ballerinas. That first exhibition incorporated images shot at a dance class held in a suburban church hall. "The light was astonishing. The people in the photographs could have been doing something else, gymnastics, painting, it didn't matter to me what they were up to. I made selections, zeroed in on a couple of particular people who had a presence, a bearing that intrigued me."
In a letter dated 14th October, 1974, one perspicacious collector, St Kilda gallerist Bruce Pollard, contacted Henson via the office of Athol Shmith offering to pay him $25 for the picture titled Carlton Afternoon, including delivery ("it would be great if you could take it to him," wrote Shmith's assistant).
Today, of course, Bill Henson is one of the most celebrated artists in the land. And while his work has evolved from those hazy, grainy early days ("Sarah Moon copied me!" he quips, though I suggest they're more Deborah Turbeville), the intensity of his gaze has never waivered. "In the end it comes down to beauty. I love beautiful things. No, that sounds weird, I'll rephrase that. It's all about what attracts the eye, and that varies tremendously from one person to the next."
ST: Are all your senses engaged, or is it uniquely the visual that concerns you?
BH: We first covet with our eyes, it's a longing for things. You can be looking at a sunset, or a beautiful piece of fabric, or a beautiful object or you can be looking at a beautiful person. To you, they have a certain grace, the way they move, the way they turn a corner of a street. It could be anything, but it's rich. For better or worse I've always been drunk on the look of things. Drunk on the weather and the light. At school, I was always picked last for the football team because I couldn't keep my eye on the ball. I was too absorbed in what was happening in nature, too busy looking at what the light was doing in the trees, or watching the occasional kid who just happened to move in a way that was distracting, disconcerting.
For Bill Henson, distraction and disconcertion are positive forces which, if harnessed with a deft hand and adroit eye can result in an extraordinary frisson. It's the shiver of early onset Stendhal syndrome I sense whenever I encounter his images.
Yet distracting and disconcerting are also charges levelled at Henson's work, oft times arising from an irrational puritanical reaction, a self-imposed verboten. Spending time in his studio, immersed in the viscous beauty of his imagery I had to confess to having no language to describe the effect. "Good," he says, looking pleased.
"Whether it's his landscapes or his still lives or his nudes, they all speak to me about the beauty of living and the pain of living," says art collector Morna Seres, a long time admirer of Henson's work. "There's something in the cusp of pubescence, the state between childhood and adulthood that really exercises that. Whether he has one or two or five figures in a picture, they're very alone. They're in their own space, there is connection but then there isn't. It reminds me of my own aloneness, it speaks to the drama of the human condition."
Henson's home is where he plays out the drama of being human with his partner, painter Louise Hearman and their Staffordshire Terrier, Mr Pigs. It was Hearman who found the abandoned, double-height, red brick former stables dating from the 1880s. "It was essentially sections of rusting corrugated iron roof tacked onto some very old, diesel- and dust-encrusted beams," Henson remembers, "and on a windy day the roof breathed in and out like a lung."
But the light was magnificent and the surrounding paddocks made it seem a bucolic idyll. Since then the meadow has been occupied by townhouses and the once desolate High Street strip mall has given rise to a new hipster enclave. A little over a decade ago, they bought the neighbouring property, converting the hangar-like garage into a semi-alfresco photo studio and trucking in a luscious garden of fully grown palms. Perfectly isolated from the outside world, it's a little bit of Palermo on the 86 tramline.
Henson and Hearman met when she was a student at the Victorian College of the Arts and he had been invited by the dean to talk to the Photography undergraduates. "I thought, Well, I'm not going to talk to them about photography. I'm going to play music to them. So I just played classical music to them in the darkroom. Louise was upstairs in the painting studio, heard the music and it drew her down the stairs. I smelt her before I saw her. She was going through a grunge phase, hadn't washed for about six months, was full-on the filthy art student. And as she came along the passageway I smelt this gin-wine-one-hundred-percent New York subway dero…"
ST: Was it love at first sight?
BH: Not quite. She said she was interested in music, so I gave her a list of things. I think I was playing Second Vienna School, so Berg and Webern and Schoenberg, and she went on her way. I came back to the VCA from time
to time to do a bit of teaching, and we just became friends. That was 1981 or '82.
ST: Gosh, you're an old couple now.
BH: (Assumes cod British accent) Oh yes, terribly old, terribly old-fashioned.
Hearman's portrait of Henson garnered her the lucrative Moran Prize in 2014. Like most of her work, it is typically described as 'dreamlike' and 'cinematic' – words that are often also attached to Henson's photographs. In many ways, the pair seem to inhabit parallel worlds, he with his cavernous atelier ground-floor left, she with her airy studio ground-floor right; a steep, narrow, black-walled staircase bisecting the building between these two creational zones.
To be clear, Henson and Hearman have nothing of the old couple about them. In fact, they're quite childlike – perhaps more Enfants du Paradis than Enfants Terribles but either way happily wrapped up in a world of their own devising. In both the physical and metaphysical senses. Their shared home is a zone of its own, a high-walled retreat, an oasis, a bastion. A place that, should the high, metal gate slide aside and Mr Pigs waddle his welcome to let you in, you enter as if into a state of grace.
Asked to describe his own work, Henson quickly slips into faux art critic shtick, and mugs: "…'Something about what goes missing in the shadows animating the speculative capacity in a way that highlights… something about just the fragment suggesting more than the whole….' They're all clichés but in fact they're no less true for being so."
Despite himself, Henson has evoked the very genius loci – the elusive spirit – of this magical place in a gritty side street off a busy thoroughfare that leads to a suburban nowhere. It's the invisible presence in so many of his images, a place/non-place that exists in the gloaming, entre chien et loup – between dog and wolf, as the French call the shadowy twilight zone of endless possibilities.
Photography by Anthony Geernaert
*With thanks to Joan Didion, Blue Nights
Tags: Anthony Geernaert, Bill Henson, stephen todd
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text:
Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail
R. C. Savin, L. Drake, D. Babel, D. M. Stewart, P. Rich, M. R. Ling, D. Breneman, R. K. Scher, A. G. Martin, D. M. Pariser, R. J. Pariser, C. N. Ellis, S. Kang, D. Friedman, H. I. Katz, C. J. McDonald, J. Muglia, G. Webster, B. E. Elewski, J. J. Leyden
A. D. Bucko, E. H. Tschen, J. M. Hanifin, M. R. Morman, J. L. Shupack, N. Levine, N. J. Lowe, W. F. Bergfeld, C. Camisa, D. S. Feingold, N. Konnikov, R. B. Odom, R. Aly, D. L. Greer, J. Hilbert
Background: Fluconazole has proven to be safe and effective for a variety of superficial and systemic fungal infections. Preliminary analysis of extensive Phase III studies suggests that it is very effective for the treatment of onychomycosis. Its pharmacokinetic properties, including low molecular weight and high water-solubility, suggest a unique ability to penetrate the nail. This feature is likely to account in part for fluconazole's effectiveness in the treatment of onychomycosis. Objective: Determinations of plasma and fingernail concentrations of fluconazole were performed as part of a larger study comparing the safety and efficacy of once-weekly fluconazole (150, 300, and 450 mg) to placebo in the treatment of distal subungual onychomycosis of the fingernails caused by dermatophytes. The relationship between fluconazole concentrations and efficacy was also examined. Methods: Pharmacokinetic studies were performed by means of plasma and fingernail samples from 133 patients, a subset of 349 patients participating in a double-blind, placebo-controlled clinical trial of fluconazole administered in once-weekly doses of 150, 300, or 450 mg until cure of onychomycosis or for a maximum of 9 months. Blood and fingernail samples for pharmacokinetic analysis were taken at baseline, at week 2, and at monthly intervals during the treatment phase of the study. Patients considered clinically cured or improved also participated in a 6-month follow-up study. During this phase, patients were monitored and samples taken every 2 months. Results: Significant amounts of fluconazole were detected in the earliest fingernail samples taken (after 2 weeks of treatment). After two weekly doses, 30% to 33% of steadystate concentrations had been achieved in healthy nails and 22% to 29% in affected nails. Steady state was achieved in 3 to 5 months. Fluconazole concentration in nails as well as plasma followed dose-proportional pharmacokinetics. Nail:plasma ratios in affected nails were 0.4 to 0.6 at 2 weeks and 1.7 to 1.8 at 6 months. Fluconazole concentrations fell slowly after drug discontinuation and were still detectable 4 months after end of treatment. A statistically significant correlation was found between steady-state concentration and clinical and global outcomes. Conclusion: Fluconazole rapidly penetrates the fingernail, where it is retained at detectable levels for at least 4 months after drug discontinuation. A significant correlation exists between fluconazole concentration in the fingernails and clinical and global out-comes.
S110-S116
Journal of the American Academy of Dermatology
6 II
Dive into the research topics of 'Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail'. Together they form a unique fingerprint.
Onychomycosis Medicine & Life Sciences 100%
Fluconazole Medicine & Life Sciences 85%
Pharmacokinetics Medicine & Life Sciences 55%
Placebos Medicine & Life Sciences 7%
Arthrodermataceae Medicine & Life Sciences 7%
Controlled Clinical Trials Medicine & Life Sciences 6%
Mycoses Medicine & Life Sciences 5%
Savin, R. C., Drake, L., Babel, D., Stewart, D. M., Rich, P., Ling, M. R., Breneman, D., Scher, R. K., Martin, A. G., Pariser, D. M., Pariser, R. J., Ellis, C. N., Kang, S., Friedman, D., Katz, H. I., McDonald, C. J., Muglia, J., Webster, G., Elewski, B. E., ... Hilbert, J. (1998). Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail. Journal of the American Academy of Dermatology, 38(6 II), S110-S116. https://doi.org/10.1016/s0190-9622(98)70494-3
Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail. / Savin, R. C.; Drake, L.; Babel, D.; Stewart, D. M.; Rich, P.; Ling, M. R.; Breneman, D.; Scher, R. K.; Martin, A. G.; Pariser, D. M.; Pariser, R. J.; Ellis, C. N.; Kang, S.; Friedman, D.; Katz, H. I.; McDonald, C. J.; Muglia, J.; Webster, G.; Elewski, B. E.; Leyden, J. J.; Bucko, A. D.; Tschen, E. H.; Hanifin, J. M.; Morman, M. R.; Shupack, J. L.; Levine, N.; Lowe, N. J.; Bergfeld, W. F.; Camisa, C.; Feingold, D. S.; Konnikov, N.; Odom, R. B.; Aly, R.; Greer, D. L.; Hilbert, J.
In: Journal of the American Academy of Dermatology, Vol. 38, No. 6 II, 1998, p. S110-S116.
Savin, RC, Drake, L, Babel, D, Stewart, DM, Rich, P, Ling, MR, Breneman, D, Scher, RK, Martin, AG, Pariser, DM, Pariser, RJ, Ellis, CN, Kang, S, Friedman, D, Katz, HI, McDonald, CJ, Muglia, J, Webster, G, Elewski, BE, Leyden, JJ, Bucko, AD, Tschen, EH, Hanifin, JM, Morman, MR, Shupack, JL, Levine, N, Lowe, NJ, Bergfeld, WF, Camisa, C, Feingold, DS, Konnikov, N, Odom, RB, Aly, R, Greer, DL & Hilbert, J 1998, 'Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail', Journal of the American Academy of Dermatology, vol. 38, no. 6 II, pp. S110-S116. https://doi.org/10.1016/s0190-9622(98)70494-3
Savin RC, Drake L, Babel D, Stewart DM, Rich P, Ling MR et al. Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail. Journal of the American Academy of Dermatology. 1998;38(6 II):S110-S116. https://doi.org/10.1016/s0190-9622(98)70494-3
Savin, R. C. ; Drake, L. ; Babel, D. ; Stewart, D. M. ; Rich, P. ; Ling, M. R. ; Breneman, D. ; Scher, R. K. ; Martin, A. G. ; Pariser, D. M. ; Pariser, R. J. ; Ellis, C. N. ; Kang, S. ; Friedman, D. ; Katz, H. I. ; McDonald, C. J. ; Muglia, J. ; Webster, G. ; Elewski, B. E. ; Leyden, J. J. ; Bucko, A. D. ; Tschen, E. H. ; Hanifin, J. M. ; Morman, M. R. ; Shupack, J. L. ; Levine, N. ; Lowe, N. J. ; Bergfeld, W. F. ; Camisa, C. ; Feingold, D. S. ; Konnikov, N. ; Odom, R. B. ; Aly, R. ; Greer, D. L. ; Hilbert, J. / Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail. In: Journal of the American Academy of Dermatology. 1998 ; Vol. 38, No. 6 II. pp. S110-S116.
@article{c4ebed707fa14d7c820a9254c5f5a3e9,
title = "Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail",
abstract = "Background: Fluconazole has proven to be safe and effective for a variety of superficial and systemic fungal infections. Preliminary analysis of extensive Phase III studies suggests that it is very effective for the treatment of onychomycosis. Its pharmacokinetic properties, including low molecular weight and high water-solubility, suggest a unique ability to penetrate the nail. This feature is likely to account in part for fluconazole's effectiveness in the treatment of onychomycosis. Objective: Determinations of plasma and fingernail concentrations of fluconazole were performed as part of a larger study comparing the safety and efficacy of once-weekly fluconazole (150, 300, and 450 mg) to placebo in the treatment of distal subungual onychomycosis of the fingernails caused by dermatophytes. The relationship between fluconazole concentrations and efficacy was also examined. Methods: Pharmacokinetic studies were performed by means of plasma and fingernail samples from 133 patients, a subset of 349 patients participating in a double-blind, placebo-controlled clinical trial of fluconazole administered in once-weekly doses of 150, 300, or 450 mg until cure of onychomycosis or for a maximum of 9 months. Blood and fingernail samples for pharmacokinetic analysis were taken at baseline, at week 2, and at monthly intervals during the treatment phase of the study. Patients considered clinically cured or improved also participated in a 6-month follow-up study. During this phase, patients were monitored and samples taken every 2 months. Results: Significant amounts of fluconazole were detected in the earliest fingernail samples taken (after 2 weeks of treatment). After two weekly doses, 30% to 33% of steadystate concentrations had been achieved in healthy nails and 22% to 29% in affected nails. Steady state was achieved in 3 to 5 months. Fluconazole concentration in nails as well as plasma followed dose-proportional pharmacokinetics. Nail:plasma ratios in affected nails were 0.4 to 0.6 at 2 weeks and 1.7 to 1.8 at 6 months. Fluconazole concentrations fell slowly after drug discontinuation and were still detectable 4 months after end of treatment. A statistically significant correlation was found between steady-state concentration and clinical and global outcomes. Conclusion: Fluconazole rapidly penetrates the fingernail, where it is retained at detectable levels for at least 4 months after drug discontinuation. A significant correlation exists between fluconazole concentration in the fingernails and clinical and global out-comes.",
author = "Savin, {R. C.} and L. Drake and D. Babel and Stewart, {D. M.} and P. Rich and Ling, {M. R.} and D. Breneman and Scher, {R. K.} and Martin, {A. G.} and Pariser, {D. M.} and Pariser, {R. J.} and Ellis, {C. N.} and S. Kang and D. Friedman and Katz, {H. I.} and McDonald, {C. J.} and J. Muglia and G. Webster and Elewski, {B. E.} and Leyden, {J. J.} and Bucko, {A. D.} and Tschen, {E. H.} and Hanifin, {J. M.} and Morman, {M. R.} and Shupack, {J. L.} and N. Levine and Lowe, {N. J.} and Bergfeld, {W. F.} and C. Camisa and Feingold, {D. S.} and N. Konnikov and Odom, {R. B.} and R. Aly and Greer, {D. L.} and J. Hilbert",
pages = "S110--S116",
journal = "Journal of the American Academy of Dermatology",
number = "6 II",
T1 - Pharmacokinetics of three once-weekly dosages of fluconazole (150, 300, or 450 mg) in distal subungual onychomycosis of the fingernail
AU - Savin, R. C.
AU - Drake, L.
AU - Babel, D.
AU - Stewart, D. M.
AU - Rich, P.
AU - Ling, M. R.
AU - Breneman, D.
AU - Scher, R. K.
AU - Martin, A. G.
AU - Pariser, D. M.
AU - Pariser, R. J.
AU - Ellis, C. N.
AU - Kang, S.
AU - Friedman, D.
AU - Katz, H. I.
AU - McDonald, C. J.
AU - Muglia, J.
AU - Webster, G.
AU - Elewski, B. E.
AU - Leyden, J. J.
AU - Bucko, A. D.
AU - Tschen, E. H.
AU - Hanifin, J. M.
AU - Morman, M. R.
AU - Shupack, J. L.
AU - Levine, N.
AU - Lowe, N. J.
AU - Bergfeld, W. F.
AU - Camisa, C.
AU - Feingold, D. S.
AU - Konnikov, N.
AU - Odom, R. B.
AU - Aly, R.
AU - Greer, D. L.
AU - Hilbert, J.
N2 - Background: Fluconazole has proven to be safe and effective for a variety of superficial and systemic fungal infections. Preliminary analysis of extensive Phase III studies suggests that it is very effective for the treatment of onychomycosis. Its pharmacokinetic properties, including low molecular weight and high water-solubility, suggest a unique ability to penetrate the nail. This feature is likely to account in part for fluconazole's effectiveness in the treatment of onychomycosis. Objective: Determinations of plasma and fingernail concentrations of fluconazole were performed as part of a larger study comparing the safety and efficacy of once-weekly fluconazole (150, 300, and 450 mg) to placebo in the treatment of distal subungual onychomycosis of the fingernails caused by dermatophytes. The relationship between fluconazole concentrations and efficacy was also examined. Methods: Pharmacokinetic studies were performed by means of plasma and fingernail samples from 133 patients, a subset of 349 patients participating in a double-blind, placebo-controlled clinical trial of fluconazole administered in once-weekly doses of 150, 300, or 450 mg until cure of onychomycosis or for a maximum of 9 months. Blood and fingernail samples for pharmacokinetic analysis were taken at baseline, at week 2, and at monthly intervals during the treatment phase of the study. Patients considered clinically cured or improved also participated in a 6-month follow-up study. During this phase, patients were monitored and samples taken every 2 months. Results: Significant amounts of fluconazole were detected in the earliest fingernail samples taken (after 2 weeks of treatment). After two weekly doses, 30% to 33% of steadystate concentrations had been achieved in healthy nails and 22% to 29% in affected nails. Steady state was achieved in 3 to 5 months. Fluconazole concentration in nails as well as plasma followed dose-proportional pharmacokinetics. Nail:plasma ratios in affected nails were 0.4 to 0.6 at 2 weeks and 1.7 to 1.8 at 6 months. Fluconazole concentrations fell slowly after drug discontinuation and were still detectable 4 months after end of treatment. A statistically significant correlation was found between steady-state concentration and clinical and global outcomes. Conclusion: Fluconazole rapidly penetrates the fingernail, where it is retained at detectable levels for at least 4 months after drug discontinuation. A significant correlation exists between fluconazole concentration in the fingernails and clinical and global out-comes.
AB - Background: Fluconazole has proven to be safe and effective for a variety of superficial and systemic fungal infections. Preliminary analysis of extensive Phase III studies suggests that it is very effective for the treatment of onychomycosis. Its pharmacokinetic properties, including low molecular weight and high water-solubility, suggest a unique ability to penetrate the nail. This feature is likely to account in part for fluconazole's effectiveness in the treatment of onychomycosis. Objective: Determinations of plasma and fingernail concentrations of fluconazole were performed as part of a larger study comparing the safety and efficacy of once-weekly fluconazole (150, 300, and 450 mg) to placebo in the treatment of distal subungual onychomycosis of the fingernails caused by dermatophytes. The relationship between fluconazole concentrations and efficacy was also examined. Methods: Pharmacokinetic studies were performed by means of plasma and fingernail samples from 133 patients, a subset of 349 patients participating in a double-blind, placebo-controlled clinical trial of fluconazole administered in once-weekly doses of 150, 300, or 450 mg until cure of onychomycosis or for a maximum of 9 months. Blood and fingernail samples for pharmacokinetic analysis were taken at baseline, at week 2, and at monthly intervals during the treatment phase of the study. Patients considered clinically cured or improved also participated in a 6-month follow-up study. During this phase, patients were monitored and samples taken every 2 months. Results: Significant amounts of fluconazole were detected in the earliest fingernail samples taken (after 2 weeks of treatment). After two weekly doses, 30% to 33% of steadystate concentrations had been achieved in healthy nails and 22% to 29% in affected nails. Steady state was achieved in 3 to 5 months. Fluconazole concentration in nails as well as plasma followed dose-proportional pharmacokinetics. Nail:plasma ratios in affected nails were 0.4 to 0.6 at 2 weeks and 1.7 to 1.8 at 6 months. Fluconazole concentrations fell slowly after drug discontinuation and were still detectable 4 months after end of treatment. A statistically significant correlation was found between steady-state concentration and clinical and global outcomes. Conclusion: Fluconazole rapidly penetrates the fingernail, where it is retained at detectable levels for at least 4 months after drug discontinuation. A significant correlation exists between fluconazole concentration in the fingernails and clinical and global out-comes.
SP - S110-S116
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 6 II


text:
Medical records -- Access control -- United States
The concept Medical records -- Access control -- United States represents the subject, aboutness, idea or notion of resources found in University of San Diego Libraries.
The Resource Medical records -- Access control -- United States
http://id.loc.gov/authorities/subjects/sh2007008835
53 Items that share the Concept Medical records -- Access control -- United States
A brief summary of the HIPAA medical privacy rule, Gina Marie Stevens
A brief summary of the medical privacy rule, Gina Marie Stevens
Access to medical records under federal law, Gina Marie Stevens
Advocating for patients : information for consumers : hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Seventh Congress, first session on examining issues related to health information for consumers, and proposed legislation that would provide assistance to the states that wish to establish, or strengthen their existing health care consumer assistance, or ombudsman programs, March 28, 2001
Assessing HIPAA : how federal medical record privacy regulations can be improved : hearing before the Subcommittee on Health of the Committee on Energy and Commerce, One Hundred Seventh Congress, first session, March 22, 2001
Compliance with the HIPAA medical privacy rule, Gina Marie Stevens
Confidentiality of health information : hearing before the Subcommittee on Health of the Committee on Ways and Means, House of Representatives, One Hundred Sixth Congress, first session, July 20, 1999
Confidentiality of patient records : hearing before the Subcommittee on Health of the Committee on Ways and Means, House of Representatives, One Hundred Sixth Congress, second session, February 17, 2000
Cybersecurity in the healthcare sector : strengthening public-private partnerships : hearing before the Subcommittee on Oversight and Investigations of the Committee on Energy and Commerce, House of Representatives, One Hundred Fifteenth Congress, first session, April 4, 2017
Description and brief analysis of H.R. 5935, Federal Privacy of Medical Information Act, Subcommittee on Health of the Committee on Ways and Means, U.S. House of Representatives
E-health, privacy, and security law, editor-in-chief W. Andrew H. Gantt III, Cooley LLP Washington DC
Electronic personal health records, Gina Marie Stevens
Enforcement of the HIPAA privacy rule, Gina Marie Stevens
Federal Privacy of Medical Information Act, H.R. 5935 : summary, justification, explanation, and comparison with present law : as approved by the Subcommittee on Health, Committee on Ways and Means, Subcommittee on Health of the Committee on Ways and Means, U.S. House of Representatives
Federal privacy of medical information act : hearing before the Subcommittee on Health of the Committee on Ways and Means, House of Representatives, Ninety-sixth Congress, second session, on H.R. 5935 ... April 17, 1980
Federal privacy of medical information act, H.R. 5935, Subcommittee on Health of the Committee on Ways and Means, U.S. House of Representatives
Fulfilling the promise of genetics research : ensuring nondiscrimination in health insurance and employment : hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Seventh Congress, first session on S. 318, to prohibit discrimination on the basis of genetic information with respect to health insurance, July 25, 2001
Genetic discrimination : overview of the issue and proposed legislation, Erin D. Williams, Amanda K. Sarata, C. Stephen Redhead
Genetic information : legal issues relating to discrimination and privacy, Nancy Lee Jones
Genetic information : legal issues relating to discrimination and privacy, Nancy Lee Jones and Alison M. Smith
Genetic testing : scientific background and nondiscrimination legislation, Michele Schoonmaker and Erin D. Williams
H.R. 4585--The Medical Financial Privacy Protection Act : hearing before the Committee on Banking and Financial Services, U.S. House of Representatives, One Hundred Sixth Congress, second session, June 14, 2000
H.R. 52, the Fair Health Information Practices Act of 1997 : hearing before the Subcommittee on Government Management, Information, and Technology of the Committee on Government Reform and Oversight, House of Representatives, One Hundred Fifth Congress, first session, on H.R. 52, to establish a code of fair information practices for health information, to amend section 552a of Title 5, United States Code, and for other purposes, June 5, 1997
H.R. 52, the Fair Health Information Practices Act of 1997 : hearings before the Subcommittee on Government Management, Information, and Technology of the Committee on Government Reform and Oversight, House of Representatives, One Hundred Fifth Congress, first session, on H.R. 52 ... to amend section 552a of Title 5, United States Code ... June 5, 1997
HIPAA medical privacy and transition rules : overkill or overdue? : hearing before the Special Committee on Aging, United States Senate, One Hundred Eighth Congress, first session, Washington, DC, September 23, 2003
HIPAA privacy, security, enforcement, and breach notification standards
Health care information confidentiality : hearing of the Committee on Labor and Human Resources, United States Senate, One Hundred Fifth Congress, second session ... February 26, 1998
Health information standards, privacy, and security : HIPAA's administrative simplification regulations, C. Stephen Redhead
Health information technology : protecting Americans' privacy in the digital age : hearing before the Committee on the Judiciary, United States Senate, One Hundred Eleventh Congress, first session, January 27, 2009
Hearing on "Improving the Coordination and Quality of Substance Use Disorder Treatment"
High-tech privacy issues in health care : hearings before the Subcommittee on Technology and the Law of the Committee on the Judiciary, United States Senate, One Hundred Third Congress, first and second sessions ... October 27, 1993, and January 27, 1994
Legislation to protect the privacy of medical records : hearings before the Committee on Governmental Affairs, United States Senate, Ninety-sixth Congress, first session, on S. 503 and S. 865, June 27, August 3, and November 13, 1979
Medical Records Confidentiality Act of 1995 : hearing of the Committee on Labor and Human Resources, United States Senate, One Hundred Fourth Congress, first session, on S. 1360, to ensure personal privacy with respect to medical records and health care-related information, and for other purposes, November 14, 1995
Medical records confidentiality in the modern delivery of health care : hearing before the Subcommittee on Health and Environment of the Committee on Commerce, House of Representatives, One Hundred Sixth Congress, first session, May 27, 1999
Medical records privacy : questions and answers on the HIPAA final rule, C. Stephen Redhead
Medical records privacy : questions and answers on the HIPAA rule, C. Stephen Redhead
Oversight of IT and cybersecurity at the Department of Veterans Affairs : hearing before the Subcommittee on Information Technology of the Committee on Oversight and Government Reform, House of Representatives, One Hundred Fifteenth Congress, first session, December 7, 2017
Patient confidentiality : hearing before the Subcommittee on Health of the Committee on Ways and Means, House of Representatives, One Hundred Fifth Congress, second session, March 24, 1998
Privacy concerns raised by the collection and use of genetic information by employers and insurers : hearing before the Subcommittee on the Constitution of the Committee on the Judiciary, House of Representatives, One Hundred Seventh Congress, second session, September 12, 2002
Privacy protections for individuals with substance use disorders : the part 2 final rule in brief
Privacy under a microscope : balancing the needs of research and confidentiality : hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Sixth Congress, first session ... February 24, 1999
Proposed rule on the privacy of individually identifiable health information : hearing of the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Sixth Congress, second session, on examining issues ... focusing on related provisions of the Health Insurance Portability and Accountability Act, April 26, 2000
Protecting against genetic discrimination : the limits of existing laws : hearing before the Committee on Health, Education, Labor, and Pensions, United States Senate, One Hundred Seventh Congress, second session, on examining the existing laws and proposed legislation necessary to protect genetic information, in order to prevent genetic discrimination that may lead to loss of health insurance or employment discrimination, including S. 318 and S. 382, to prohibit discrimination on the basis of genetic information with respect to health insurance, February 13, 2002
Protecting health information : legislative options for medical privacy : hearing before the Subcommittee on Government Management, Information, and Technology of the Committee on Government Reform and Oversight, House of Representatives, One Hundred Fifth Congress, second session, May 19, 1998
Protecting patient privacy in healthcare information systems : hearing before the Subcommittee on Information Policy, Census, and National Archives of the Committee on Oversight and Government Reform, House of Representatives, One Hundred Tenth Congress, first session, June 19, 2007
Ransomware attacks renew focus on HIPAA security standards, C. Stepehn Redhead
Strengthening Partnerships to Prevent Opioid Abuse Act : report (to accompany H.R. 5715) (including cost estimate of the Congressional Budget Office)
Summary of the proposed rule for the privacy of individually identifiable health information, Gina Stevens, Melinda DeAtley
The Fair Health Information Practices Act of 1994 : hearings before the Information, Justice, Transportation, and Agriculture Subcommittee of the Committee on Government Operations, House of Representatives, One Hundred Third Congress, second session, on H.R. 4077 ... to amend section 552a of Title 5, United States Code ... April 20, May 4 and 5, 1994
The Medical Information Protection and Research Enhancement Act of 1999 : hearing before the Subcommittee on Health and Environment of the Committee on Commerce, House of Representatives ; One Hundred Sixth Congress, first session ; July 15, 1999
The role of FCRA in employee background checks and the collection of medical information : hearing before the Subcommittee on Financial Institutions and Consumer Credit of the Committee on Financial Services, U.S. House of Representatives, One Hundred Eighth Congress, first session, June 17, 2003
Your health and your privacy : protecting health information in a digital world : hearing before the Subcommittee on Privacy, Technology and the Law of the Committee on the Judiciary, United States Senate, One Hundred Twelfth Congress, first session, November 9, 2011
Context of Medical records -- Access control -- United States
A brief summary of the HIPAA medical privacy rule
A brief summary of the medical privacy rule
Access to medical records under federal law
Compliance with the HIPAA medical privacy rule
Description and brief analysis of H.R. 5935, Federal Privacy of Medical Information Act
E-health, privacy, and security law
Electronic personal health records
Enforcement of the HIPAA privacy rule
Federal Privacy of Medical Information Act, H.R. 5935 : summary, justification, explanation, and comparison with present law : as approved by the Subcommittee on Health, Committee on Ways and Means
Federal privacy of medical information act, H.R. 5935
Genetic discrimination : overview of the issue and proposed legislation
Genetic information : legal issues relating to discrimination and privacy
Genetic testing : scientific background and nondiscrimination legislation
Health information standards, privacy, and security : HIPAA's administrative simplification regulations
Medical records privacy : questions and answers on the HIPAA final rule
Medical records privacy : questions and answers on the HIPAA rule
Ransomware attacks renew focus on HIPAA security standards
Summary of the proposed rule for the privacy of individually identifiable health information

 Data from Medical records -- Access control -- United States - University of San Diego Libraries

Data Citation of the Concept Medical records -- Access control -- United States


A new partnership between Manchester Community College (MCC) and Franklin Pierce University (FPU) will allow students to earn a Bachelor of Science Degree in Nursing from FPU in one year after earning their Associate Degree in Nursing (ADN) from MCC. Students in the Pathway for NH's Future Nurses program will not have to apply separately to FPU after earning their ADN because they will have been accepted to both colleges as freshmen. By spending most of their first three years at MCC, students will save thousands of dollars in tuition over the cost of attending a traditional four-year college for their BS in Nursing.
Elliot Health System (EHS) in Manchester is a key partner in the new program. Students in the Pathway for NH's Future Nurses program will do a 192-hour preceptorship in their third year, working alongside an Elliot RN, an experience not available in a traditional associate degree program.
Students accepted into the Pathway program will take courses that meet the requirements of both colleges during their first three years at MCC, receive their ADN, and be eligible to take the RN state board exam (NCLEX-RN). They will then complete their bachelor degree in nursing at FPU during the fourth year.
"This new agreement offers real advantages to nursing students who want to achieve their bachelor degree in nursing within four years of beginning their college careers," says MCC President Dr. Susan Huard. "Students in this new program will earn their ADN and be ready to take the RN exam while they're still working towards their bachelor degree. And they're assured from the first day on MCC's campus that they have a place at FPU to finish their bachelor degree!"
"FPU has a strong RN-to-BSN program in place," says Associate Dean John Ragsdale of FPU, "and the graduates of MCC's ADN program consistently show the highest pass rates on the state nursing exams, so they're well-positioned to succeed in our program. Students in the new program will transition seamlessly from MCC to FPU and benefit from the high quality of both programs. It's a win-win-win for the students, for MCC and for FPU."
"And it's a win for EHS as well," says Joni Spring, RN, Vice President of Patient Care Services and Chief Nursing Officer at Elliot Health System. "We have a strong relationship with MCC, and have served as a clinical site for their nursing students for many years. We encourage our RNs with associate degrees to continue their education, so this new partnership will help us assure a strong nursing staff throughout our system."
Applications will be accepted for the Fall 2012 class after March 8th. Interested students should plan to attend one of the information sessions for details about the Pathway for NH's Future Nurses program.


Wow, what a choice we have in Wrexham on Thursday (29th) reopening of McDonald's with its swanky new electronic ordering, promotional burger meals vs official opening of Ty Pawb. Good luck to those businesses that have invested in their stalls or eateries but I bet Mcdonald's footfall is a lot higher than Ty Pawb will ever be.
Well, it definitely Maccy D's for me. I know I can get a decent cup of coffee for less than £2 and a tea for 99p.
Whatever you're smoking 'aint been stashed in a bin in the town centre.
I can tell you one thing, looking at the comments on various Facebook posts/groups McDonald's has significantly better PR than Ty Pawb. At least McDonald's don't publicly try to attack their critics, but instead try and engage with them in a positive manner. I've seen several people being personally criticised and discredited for making even the slightest negative comment about Ty Pawb or expressing any level of concern over the whole thing, even if it has been something very subtle and non-offensive over a pre-existing issue like "Well the People's Market Building looks a bit ugly for an Arts Hub".
The people attacking the detractors are people who are clearly involved in Ty Pawb, so have loads at stake in making the place a success, but completely alienating prospective local visitors by behaving fearful of any negativity and trying to discredit them is p*ss poor PR in my books. Would they rather it was like the Emperor's New Clothes? and everyone is to scared to speak out.
At the end of the day the way to really slap us critics down and show us up would be for them to focus and concentrate all their efforts on making the place a roaring success. They wouldn't even need to say a thing then, we'd all just end up looking mightily foolish and be forced to admit that we were wrong.
The significant non-attendance from Council members (note the number of uncollected badges at the opening) may reflect that there is a real division in our Council Members. There seems to have been a distancing also by our local politicians AMs and MPs. Do they know something already – Lesley Griffiths perhaps learnt a lesson having opened Sprouts Nursery and then saw it close within two years.


Introduction: Due to more than 1.7 million population, many vehicles and large industries around Isfahan, it has become one of the most polluted cities in Iran. The aim of this study was a spatial analysis of the concentrations of air pollutants and the air quality index (AQI).
Materials and Methods: In this descriptive and evaluative study, the air quality data of 7 monitoring stations in 2012 were taken from the Isfahan Department of Environment. The calculation of AQI was done as per the EPA guidelines. The zoning pollutant concentrations and AQI in the study area was determined with the use of the Arc map software, version 10.1.
Results: The results showed that the highest concentrations of pollutants and the AQI were related to the Ahmadabad station. Moreover, the air quality in Isfahan in 2012 was 4.38% (4 days) in good conditions, 12.7% (47 days) in moderate conditions, 42.56% (156 days) in unhealthy conditions for sensitive groups, 39.49% (144 day) in unhealthy conditions, 2.8% (10 days) in a very unhealthy and 1.2% (4 days) in dangerous conditions, respectively.
Conclusion: It was found that particulate matter was the main cause of Isfahan air pollution while Ahmadabad is the most polluted point in Isfahan. According to the calculations, during 314 days of the year 2012, the air quality of Isfahan was in unhealthy conditions and only 4 days was in good conditions. This is one of the biggest health challenges in this city.


text:
Published: Mar 4th, 2010
Category: Media
Tags: DRM, PC Gamer, Ubisoft
Ubisoft's new draconian DRM that was supposed to require a permanent internet connection while playing single-player games has been cracked a mere 25 hours after release of the first PC game to have the DRM – Silent Hunter V.
For their part, Ubisoft deny the viability of the cracked copies:
"Please know that this rumor is false and while a pirated version may seem to be complete at start up, any gamer who downloads and plays a cracked version will find that their version is not complete."
Specifically, the server-based cloud system for savegames is not available. Y'know, the "feature" they added along with the DRM that nobody gives a shit about because nobody plays the same game on two different computers. To quote the Tom Francis at PC Gamer:
"The only benefit we're being offered is the ability to store our savegames online. Personally, I'm in the rare position of getting to play PC games at work, and even for me this is a fringe benefit."


PHP stands for PHP Hypertext Preprocessor. PHP course in Jaipur is an HTML-embedded scripting language. iGlobe Solutions provides Core PHP training in Jaipur according to the current requirement of IT industry. Much of its syntax is borrowed from C and Java with a couple of unique PHP-specific features thrown in. The goal of the language is to allow web developers to write dynamically generated pages quickly.


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Latest GK and Current Affairs November 2018 (Week 2) – 25 MCQs
by admin | Nov 12, 2018 | Current Affairs & GK Question Answers | 0 comments
Latest GK November 2018 (Week 2) – Video and Pdf
Latest GK and Current Affairs November 2018 (Week 2) – This Video includes the Latest Current Affairs in MCQ format covering the Current Affairs during week 4th to 10th November 2018. The topics covered in the video are science and technology, Space research, Awards and honours, Entertainment, Sports, Politics, etc. The important details of the current affairs are also discussed in the video so that all possible questions can be prepared.
See Latest GK November 2018 (Week 2) Video
The Questions provided in the video are:
Q1. Recently, US has imposed sanctions on which country?
Q2. The United Nations Postal Administration has launched new stamps to commemorate which festival?
Q3. The newly built international stadium in the capital of which state will be renamed after Atal Bihari Vajpayee?
Q4. Who has set a world record by winning the gold medal in men's skeet final of the 8th Asian Shotgun Championship?
Q5. Name India's 1st nuclear-powered ballistic missile submarine?
Q6. When is the World Tsunami Awareness day observed every year?
Q7. Name India's 1st indigenously developed microprocessor, developed by IIT – Madras?
Q8. Name India's new Ambassador to Iran?
Q9. Saudi Arabia has banned the entry of Haj pilgrims from which country?
Q10. Who is the chairman of Tesla?
Q11. In order to boost tourism, which country has waived off the fee for Visa – on – arrival?
Q12. Name the Attorney General of USA, sacked by US President Donald Trump?
Q13. The Supreme court has announced the setting up of a separate high court for which state?
Q14. Name the biography of AR Rehman?
Q15. Which of these is not one of the 8 countries who have been granted Iran oil waiver by the USA?
Q16. Bengaluru based cab service 'OLA' is not operating in which of these countries?
Q17. Name the recipient of the IPI-India Award for excellence in journalism 2018?
Q18. Where was the 18th Indian Ocean Rim Association (IORA) Council of Ministers Meeting held?
Q19. Name the world's largest supercomputer?
Q20. Pari Singh from Jharkhand headed the high commission of which country for a day?
Q21. In which city is the 'Signature bridge' located?
Q22. Which country has unveiled a sculpture in honour of Indian soldiers?
Q23. According to the Sustainability Index released by Arcadis, which is Asia's most sustainable city?
Q24. The Little India Gate is located in which country?
Q25. Which of these High court Chief Justices has been elevated as Supreme Court judge?
Download CA 4th to 10th November 2018 PDF File FREE Click here


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Ship Mission Reports
Exploring Shipwrecks Near A Black Hole, USS Juneau Makes An Exciting Discovery
February 10, 2021 in Ship Mission Reports
AAVARO WILDS — Preparation made for exciting results, as the USS Juneau (NX-99801) continues exploring the Aavaro Wilds. When the USS Eagle (NCC-74659), later replaced by the Juneau, originally arrived in the area, it sent several probes out into the reaches of the region to better prepare them for what they may encounter.
One of those probes paid dividends already as the crew of the Juneau received data leading them to investigate a unique sight in this remote corner of the galaxy. As they approached the location recorded by the probe, the Juneau stared into a black hole. On closer inspection, the crew discovered two vessels trapped in the pull of the gravity well. One was of unknown origin, while the other was a Mithgiln vessel, ostensibly ripped in half.
After the crew created a relay of probes to draw information from the aftermath of the collision, the shocking discovery was that the black hole had captured the ships thousands of years ago and they drifted there ever since.
With the discovery of a living time capsule where both ships are nearly double the size of the Juneau itself, they wasted no time in dispatching an away team to the Unknown vessel. Once the team successfully reached the ship and docked, they found a ghost ship waiting for them. Further exploring led to the discovery of what appeared to be a battle scene within the claustrophobic halls of the ship.
At the same time as the away team discovered an area that resembled a cell block, the crew still on the Juneau discovered a signal coming from the remains of the Mithgiln ship.
"The recording was from the crew, made seconds after impact," explained CWO3 C'Trow, First Officer's Aide. "Marshal Ulian Lentir, of the Grey Star College, related from across the millennium how the other ship lured them to the edge of the black hole with a distress call."
More on this story as it develops.
Written by Jansen Orrey
The post Exploring Shipwrecks Near A Black Hole, USS Juneau Makes An Exciting Discovery appeared first on StarBase 118 Star Trek RPG.
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The THAAD system pictured here is a globally transportable, rapidly deployable capability to intercept and destroy ballistic missiles inside or outside the atmosphere during its final phase of flight, according to DoD's Missile Defense Agency website. Lockheed Martin photo
North Korea Launches New Missile, However Test Fails
April 29, 2017 Eurasia Review 0 Comments
By Eurasia Review
North Korea defied world pressure and launched early Friday a new ballistic missile test. The launch is reported to have exploded not long after lifting off.
The US Pacific Command said it detected a North Korean missile launch at 5:33 a.m. local time. The ballistic missile launch occurred near the Puk Chang airfield.
The missile did not leave North Korean territory, with debris reported to have landed in the East Sea.
Related Article: Pacom Commander: North Korea Threatens Indo-Asia-Pacific Region
The North American Aerospace Defense Command (NORAD) determined the missile launch from North Korea did not pose a threat to North America.
In a tweet, US President Donald Trump said, "North Korea disrespected the wishes of China & its highly respected President when it launched, though unsuccessfully, a missile today. Bad!"
US Pacific Command reiterated that it "stands behind our steadfast commitment to the security of our allies in the Republic of Korea and Japan."
Related Article: US-North Korea Military Swashbuckling And China's Role – Analysis
On Thursday, US Secretary of State Rex Tillerson told the UN Security Table that, "All options for responding to future provocations must remain on the table."
"Diplomatic and financial leverage or power will be backed up by willingness to counteract North Korean aggression with military action, if necessary," Tillerson added.
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