text:
← CURA's Visiting Fellowship Scheme Open
An Anti-homeless Public Space By Simon Stevens, DeMontfort University →
Informal Working Practices and the Governance of Everyday Life
Posted on October 11, 2019 by jcauva00
In this blog, CURA's Adam Fishwick (@Adam_Fishwick) and Valeria Guarneros-Meza (@valguarn) develop three avenues of enquiry relating to urban informality, following a one day workshop held in June 2019.
Informality, although a contested concept, has been considered relevant by interdisciplinary approaches to studying urban and rural environments as it has helped to unpick rapid transitions, change and resilience in periods of economic, political and social crises, while also helping to challenge injustices. For a recent debate see Acuto et al. (2019)
Urban environments provide dynamic sites for understanding the ways in which the state – intentionally or otherwise – produces and reproduces the informal practices enacted by individuals and communities. The state has played an important role in manufacturing forms of informality, in housing, planning, infrastructure and the other areas of life, as well as in managing, containing or co-opting the everyday practices of local populations, albeit in complex and contradictory ways.
Similarly, informal work plays a central role in political economies across localities in the Global South and, increasingly, Global North. Myriad forms of informal work cut across formal labour markets, contributing to capital accumulation as a cheap and disposable source of labour power, with the state being complicit in its spread and consolidation, again, in complex and contradictory ways.
Informal work provides a means of survival for poorer communities, particularly in the absence and decline of social provision, but, more importantly, it also engenders new dynamics of class formation and reproduction, with opportunities for new forms of collective organisation.
With this preamble in mind, new questions have risen that aim to unpick how different dimensions (economic, institutional/legal and social) of informality intersect with new understandings of work and class formation. Although the rural context is increasingly experiencing drastic changes as a result of capital accumulation and its associated technology, financialisation and precarity, the preference of the workshop upon the urban was justified as a result of austerity policies affecting social policies even deeper than previous decades and of increasing international migration rates that have been putting pressure to urban problems already accentuated by austerity in both global South and North.
These questions formed part of the agenda of a CURA-sponsored one-day workshop in June 2019, co-sponsored by LGRC and POWI. Here we set out three avenues of inquiry that emerged in the course of the discussions among participants and which we believe can guide innovative research, which will be fruitful to achieve through comparative and interdisciplinary collaboration:
Avenue 1: value and commodity chains
Informal work and labour are central to value chains and the production of value across cities. Reflections in the workshop on waste collection across Argentina and Nigeria illustrated the centrality of informal workers to the production of value through their incorporation into existing production networks coordinated by the state and private companies.
Discussions drew out the complexity of value production at the intersection of boundaries between state regulation, private sector accumulation and everyday practices of social reproduction. In particular, these exposed the intensification of exploitation that occurred with the incorporation of informal workers into the "formal" sphere – from state-subsidised waste collectors in Buenos Aires to the navigation of state repression and corruption in Lagos.
Theoretical discussion based on extensive field research in sub-Saharan Africa also focused on the limits of the concept of informality by asking not only how value is produced, but also how different practices are valued. This opened further debate around how we understand what counts within different informal practices, how these reproduce life, and how state actors' interpretations contribute to their value formation.
Avenue 2: social reproduction and resistance
The spaces that are (re)produced by informal urban practices can enable marginalised populations to survive while, at the same, provide possibilities for new collective action and resistance. This was one of the key discussions throughout the workshop, drawing on diverse cases in Argentina, Mexico, Nigeria and the UK to explain how shared experiences of informality, exploitation and marginalisation enabled novel forms of collective organisation.
Contributions showed how sites of social reproduction were as significant to collective organisation as sites of production, demonstrating how the reproduction of life at the margins of cities can provide resources for resistance. Informal workers in waste collection, for example, pressured local government in Buenos Aires for formal recognition, while migrant workers in hostels in the UK developed new forms of sociality and solidarity as they navigated the "formal" means for their own reproduction.
This blurring of boundaries between production and reproduction was particularly clear when unpacking the working of informal practices of governance. For example, in examining the processes of land tenure and housing in Brazil and London, respectively, discussion centred on how contested processes of formalisation and informal agreements between elites and marginalised populations simultaneously addressed challenges of informal living while heightening the possibility of exploitation through private renting and state policy.
Avenue 3: state reproducing informality
It is widely recognised that the state is a main contributor to informal procedures that build differences in power relations. The discussions unpicked this aspect about the role of the state and the ways it influences the organising possibilities amongst precarious workers whose labour spans between the public (government) sector and informal markets. This was particularly observed in waste management in Argentina, Nigeria and Mexico.
These cities illustrated how the public sector provides a window for individuals to join the formal labour market, while individuals continue to draw on dynamics that interweave with social struggles based on self-governance to cope with the exploitation that the public sector increasingly applies. The latter contributes to the invisibilisation of waste workers through the beliefs of senior bureaucrats that were consequently reflected in government documents, all of which fed the concealment of informality within the state.
Concealment extends to areas of state violence, for example, in London and Madrid the cleansing activities that the state uses to eradicate stigmatised communities of immigrants in housing and the increasing coordination with policing and immigration enforcement agencies. However, the informality of the state can produce positive results. For example, during the period Barcelona was ruled by Barcelona em Comú, bureaucrats were closely involved in the social struggle aiming to change government's informal practice in the fight against the austerity of social policies.
The authors are grateful to the workshop speakers and other participants for the ideas developed in this post. The speakers include:
Dr Begoña Aramayona (Universidad Autónoma de Madrid)
Dr Maurizio Atzeni (Centro de Estudios e Investigaciones Laborales, Argentina)
Dr Precious Akponah (University of Leicester)
Raphael Bishof (De Montfort University/ Universidade Federal do ABC, Brasil)
Theodor Born (Queen Mary, UoL)
Dr Adam Fishwick (De Montfort University)
Dr Valeria Guarneros-Meza (De Montfort University)
Dr Louise Guibrunet (Universidad Nacional Autónoma de México)
Prof. Vivien Lowndes (University of Birmingham)
Dr. Colin Marx (Bartlett Development Planning Unit, UCL)
Jacob Nielsen (University of Liverpool)


text:
Східний Самар (вар.: Sidlangan nga Samar; себ.: Sidlakang Samar; філ.: Silangang Samar) — провінція Філіппін, розташована в регіоні Східні Вісаї на острові Самар. Адміністративним центром провінції є місто Боронган. Провінція межує на півночі з провінцією Північний Самар, на заході — з провінцією Самар, на сході лежить філіппінське море, на півдні — затока Лейте.

Площа провінції становить 4 660 км2.

Примітки

Посилання

 Philippine Standard Geographic Code
 Local Governance Performance Management System

Східні Вісаї
Провінції Філіппін
Самар (острів)

redpajama_set_name: RedPajamaWikipedia


text:
Eyjafjallajökull peut désigner :
 l'Eyjafjallajökull, glacier islandais ;
 par métonymie, l'Eyjafjöll, montagne et volcan situé sous ce glacier connu pour son éruption en 2010 ayant entraîné des perturbations dans le trafic aérien en Europe ;
 , astéroïde nommé d'après le glacier ;
 Eyjafjallajökull, film français sorti le .


The second Borei-class SSBN (Alexander Nevsky) is fitting out at the Severodvinsk Naval Shipyard in northern Russia. Six of its 16 missile tubes are open on this August 2011 satellite image by DigitalGlobe/GoogleEarth.
The Russian ballistic missile submarine fleet is being modernized but conducting so few deterrent patrols that each submarine crew cannot be certain to get out of port even once a year.
During 2012, according to data obtained from U.S. Naval Intelligence under the Freedom of Information Act, the entire Russian fleet of nine ballistic missile submarines only sailed on five deterrent patrols.
The patrol level is barely enough to maintain one missile submarine on patrol at any given time.
The ballistic missile submarine force is in the middle of an important modernization. Over the next decade or so, all remaining Soviet-era ballistic missile submarines and their two types of sea-launched ballistic missiles will be replaced with a new submarine armed with a new missile (see also our latest Nuclear Notebook on Russian nuclear forces).
The new fleet will carry more nuclear warheads than the one it replaces, however, because the Russian military is trying to maintain parity with the larger U.S. nuclear arsenal.
The operational tempo of the Russian SSBN fleet – measured in the number of deterrent patrol conducted each year – has declined significantly – actually plummeted – since the end of the Cold War.
At their peak in 1984 – the year after the Russian military became convinced that the NATO exercise Able Archer was in fact disguised preparations for a nuclear first strike against the Soviet Union, Russian SSBNs carried out 102 patrols. Under Mikhail Gorbachev, operations quickly declined in the second half of the 1980s. But even as the Warsaw Pact collapsed and the Berlin Wall fell in 1989, the fleet was able to muster a slight comeback in 1990.
As the Cold War officially ended in 1990, the Soviet Union dissolved and Russia descended into financial recession, the SSBN force increasingly stayed in port until in 2002, when no deterrent patrols were conducted all.
Since then, the performance has been a mixed bag. After a slight whiff of new life with 10 patrols in 2008 (up from 3 in 2007), the number of SSBN patrols has declined again to around five in 2012.
The recent decline contrasts with the Russian Navy's declaration last year that it would resume continuous deterrent patrols from mid-2012. Assuming the five patrols occurred throughout the year and not just in the last six months, the fleet would have had a hard time maintaining a continuous at-sea presence with only five patrols. Theoretically, it could be done if each patrol lasted an average of 73 days. That is how long a U.S. SSBN deploys on a good day. But Russian SSBNs are thought to do shorter patrols, probably 40-60 days each, in which case most of the five patrols would have had to occur between July and December to maintain continuous patrol from mid-2012.
Even if the navy were able to squeeze a more or less continuous at-sea presence out of the five patrols, it would at best have consisted of a single SSBN – not much for a fleet of nine submarines or demonstrating a convincing secure retaliatory capability.
Perhaps more significantly, the five deterrent patrols conducted in 2012 are not enough for each SSBN in the fleet to be able to conduct even one patrol a year. The five patrols by nine SSBNs indicate that only five or less submarines are active. That means that submarine crews do not get much hands-on training in how to operate the SSBNs so they actually have a chance to survive and provide a secure retaliatory strike capability in a crisis. Crews probably compensate for this by practicing alert operations at pier-side at their bases.
Unlike U.S. SSBNs, which can patrol essentially with impunity in the open oceans, Russian deterrent patrols are thought to take place in "strategic bastions" relatively close to Russia where the SSBNs can be protected by the Russian navy against the U.S. and British attack submarines that probably occasionally monitor their potential targets.
The Russian navy remembers all too well the 1980s when the aggressive U.S. Maritime Strategy envisioned using attack submarines to hunt down and destroy Soviet SSBNs early on in a conflict, a highly controversial strategy [see here and here] that could likely have triggered escalation to strategic nuclear war. Hunting Russian SSBNs is no longer a primary mission for U.S. attack submarines, but it is probably still part of the mission package and one that Russian planners cannot afford to ignore. As a result, Russian SSBNs probably continue to patrol in the areas used in the late-1980s and early-1990s (see map) to provide maximum protection.
Russia currently operates 10 ballistic missile submarines (SSBNs), of which three Delta IIIs based in the Pacific are outdated and six Delta IVs based in the Barents Sea have recently been refurbished to serve for another decade or so. The 10th SSBN added in January 2013 is the first of a new type of Borei-class SSBNs that are scheduled to replace all Deltas by the mid/late-2020s.
The first Borei-class (Project 955) SSBN, Yuri Dolgoruki, entered service after more than 15 years of design and construction, marking the first time in 25 years that the Russian Navy had commissioned a new SSBN. A second Borei has been launched and a third is under construction. Russia has announced plans to build a total of eight Boreis. Each Borei is equipped with 16 SS-N-32 (Bulava) SLBMs, a missile that Russia has declared can carry up to six warheads.
The fourth and subsequent Borei-class SSBNs will be of an improved design, known as Borei-II or Project 955A). Russian news media is full of rumors that the improved Boreis will be equipped with 20 SLBMs instead of 16 on each of the first three boats. Some Russian officials dispute that, saying all Boreis will be equipped with 16 missiles.
This force structure plan has implications for Russia's nuclear posture and strategic priorities. The replacement of the Delta SSBNs with eight Borei SSBNs will reduce the size of the Russian SSBN fleet and the number of SLBMs, but result in a 23-percent increase in the number of sea-based warheads because the SS-N-32 carries more warheads than the SS-N-18 and SS-N-23 SLBMs it replaces.
In other words, Russia will be placing more eggs in fewer baskets at sea, which increases the importance of each SSBN – something strategists say is bad for crisis stability.
The Russian SSBN force is in the middle of a transition from Soviet-era weapons to a smaller but more warhead-heavy fleet of new submarines.
This means that the SSBN fleet will carry a growing portion of Russia's strategic missile warheads – up from about a third today to nearly half by the mid-2020s.
The trend of increased warhead loading on sea-launched ballistic missiles is similar to the development on land where reduction of the Russian ICBM force will result in a greater portion of the remaining force being equipped with multiple warheads.
This is perhaps the most dominant trend of Russia's nuclear forces today: fewer launchers but each carrying more warheads. Not that Russia will have more total nuclear warheads than before (their arsenal is declining), but that military planners have fallen for the temptation to place more nuclear eggs in each basket.
They appear to do so to compensate againt the larger U.S. nuclear missile force and its significant reserve of additional warheads. But it would be helpful if the Russian government would declare how many Borei-class SSBNs it plans to build in total and limit the number of missiles on each to 16.
The Russian modernization is motivating Cold Warriors in the U.S. Congress to argue that the United States should not reduce but modernize its nuclear forces. They are wrong for many reasons, not least because the two postures are very different.
The U.S. SSBN fleet is more modern with another 15 service years left in it, and it carries many more missiles that are much more reliable with more warheads. The U.S. could in fact easily reduce its SSBN fleet to ten boats, perhaps fewer.
Moreover, in contrast with U.S. SSBN operations, where each operational submarine conducts an average of 2-3 patrols each year, Russian SSBN crews do not get a lot of operational training with an average of less than one patrol per submarine per year.
Rather than opposing further reductions, U.S. lawmakers should support limitations on the growing asymmetry between U.S. and Russian strategic nuclear forces – an asymmetry that is significantly in the U.S. advantage – to help limit further concentration of nuclear warheads on Russia's declining numbers of strategic missiles. That would actually help the national security interests of all.
Many assumptions in those writeup and assuming ONI estimates like any intelligence estimates are Gospel Truth , it would indicate that either Russian SSBN are not ready for long deterrent patrol at sea or the Delta 4 are still goes modernisation with their new Liner SLBM which will replace the Sineva SLBM.
The author is not sure about these deterrent patrol is for a period of a year or 6 months and how long do each of these deterrent patrol last , there are some assumptions made there.
The Russians maintain a significant part of triad on Land Based ICBM so a low patrol would not necessarily imply low nuclear deterrent potential.
Its officially confirmed now that till 2020 Russia would build 8 Borei class SSBN , 3 x 955 class and 5 x 955U or improved Borei , both would carry 16 Bulava SLBM respectively.
The bastion strategy is not something unique to Russians , even Western/US submarine patrol in selected areas guarded by SSN if needed , reason why French and British SSBN ended up bumping each other as they operated in a fixed area during deterrent patrol.
As long as your SLBM can reach your potential targets from the area you patrol there is no need to patrol the open ocean and no one does that expect perhaps for SSN.
The reducing of Russian SSBN deterrence patrols is indeed hard swallowed by both Naval High Command and those "old-timers" officers who still serve after long years of service in the Soviet Navy. But this reduction is something to be expected after the colossal event the falling of European Communism was. As a matter of fact, personally I think that how Russia tried and tries to catch up and set itself on its feet again is quite exceptional.
Coming back to the topic. To me, maintaining a high rate of SSBN patrols (like the US Navy does) mean only one thing: you still want to be prepared for a first-strike nuclear kill. You still want to be able to hit first. Unlike SSNs and SSGNs, boomers have after all, only one purpose. They were and are the big MAD concept killers. They were developed in the beginning with this strategy in mind and afterwards their operations were ironically used to counteract the exact same strategy (especially by the Soviet Navy). Nowadays, their deployments seem to render them as exclusively second-strike capability platforms. Or do they?
In this respect, the Russian SSBNs doesn't need their US counterparts' 2-3 patrols/boat/ year. Those 5 patrols in 2012 were sufficient to assure a second-strike and massive destruction of a potential attacker. As far as the training of the crews including all the related readiness is concerned , now that hurts a lot for sure but things look for the better in the near future for the Russian Navy.


text:
https://sixerswire.usatoday.com/2020/04/24/2010-nba-re-draft-sixers-select-john-wall-at-2-instead-of-evan-turner/
2010 NBA re-draft: Sixers select John Wall at 2 instead of Evan Turner
Howard Smith-USA TODAY Sports
The 2010 NBA Draft was filled with future stars. From John Wall to Paul George to DeMarcus Cousins, there were a lot of talented players to pick from. The Philadelphia 76ers held the second overall pick in that draft and after Wall was selected, they selected Evan Turner out of Ohio State. Turner did not have the same kind of impact as his classmates, to put it kindly.
Fast forward 10 years later and now is the time for a re-draft. A lot has happened in those 10 years and there have been some impressive performances from this draft, but would Wall go number 1 again in the re-draft? Not according to most.
In this case, Bleacher Report has George being selected first overall by the Washington Wizards which clears the way for Wall to be selected by Philadelphia at number 2.
B/R:
The consensus No. 1 pick at the time, Wall mostly lived up to the hype in his first eight years with the Wizards before missing most of the past two seasons with major injuries. One of the fastest, most explosive point guards in the NBA over the past decade, Wall made five straight All-Star teams from 2014 to 2018 and was named third-team All-NBA in 2016-17.
Wall and 2012 No. 3 pick Bradley Beal led the Wizards to the franchise's best stretch in years, gradually dragging the team out of the laughingstock years of the late 2000s into Eastern Conference respectability. Washington made the playoffs four out of five seasons from 2014 to 2018, and made the second round three times.
The one knock on Wall's career has been his health. He suffered various knee and wrist injuries over the years that caused him to miss time, and during the 2018-19 season, he suffered a torn Achilles that has kept him out since.
Could you imagine a backcourt of Wall and Jrue Holiday with Andre Iguodala? That would be one of the longest and athletic lineups in the league. When healthy, Wall is one of the more explosive point guards in the league, and Holiday has the size to play some shooting guard which is what he does now on occasion for the New Orleans Pelicans.
As for Turner, he was selected 12th overall in the re-draft by the Memphis Grizzlies. During his time in Philadelphia, he did average 11.5 points and 5.5 rebounds.
Tobias Harris reacts to video of Matisse Thybulle copying him in warmups
Matisse Thybulle earns a spot on All-Rookie Second Team from ESPN
Josh Richardson to donate 500,000 meals to city of Philadelphia

redpajama_set_name: RedPajamaCommonCrawl


Radius is a science-driven fully integrated biopharmaceutical company that is committed to developing and commercializing innovative endocrine therapeutics in the areas of osteoporosis and oncology. Attracting and developing high performing team members is the key to our success. If you are seeking to become part of our outstanding team of professionals, we invite you to apply online today.


Glass.Net is here to help customers in Saddle Brook, New Jersey replace or repair cracked or damaged auto glass in an affordable manner. With our easy-to-use two-step system, we can help you find the lowest prices from the most reputable auto glass specialists.
Glass.net makes it easy to get repairs for a broken windshield in Saddle Brook, NJ. In fact, all you have to do is complete two easy steps and you'll get quotes from three different businesses. All these businesses use OEM or equivalent quality glass to replace rear windows, side windows, windshields and any other auto glass that might need to be replaced.
They can also affect repairs on broken windshields, in some cases, and many of them will travel right to where you are located at any time of the day or night. This is the best way to handle a situation when driving a vehicle would be dangerous because of a broken windshield and allows you to get the work done without having to risk getting a ticket or having an accident. It's never been easier to get in touch with good Saddle Brook, NJ auto glass repair specialists than it is here.
Thankfully, windshield replacement in Saddle Brook has never been easier for you as a Saddle Brook resident. And it's a good thing too, because a cracked or damaged windshield can be dangerous for both you and your passengers. Even more, it's entirely possible that driving with a damaged windshield in New Jersey is against the law.
Avoid injury or potential legal trouble by having your windshield repaired in Saddle Brook, New Jersey today. Our auto glass repair specialists near you in Saddle Brook are more than qualified to repair your windshield or replace it. In most cases, these specialists can come right to your home in Saddle Brook to replace or repair your windshield. This means you won't have to take valuable time out of your day to get it fixed!
Curious about auto glass repair quote statistics for Saddle Brook? We've compiled these from our current quote data at Glass.Net. You can find this in the tables below.
How much does it cost to replace a windshield in Saddle Brook, New Jersey?
How much does it cost to replace your side window in the city of Saddle Brook, New Jersey?
How much does it cost to replace the rear window in the city of Saddle Brook, New Jersey?
Saddle Brook, New Jersey automotive glass repair cost varies by vehicle type and the type of window being repaired. Using our proprietary data, we calculated the past year's average cost of car window repairs in Saddle Brook, New Jersey for foreign vehicles versus domestic vehicles and trucks/SUV's. We display this data by window type in the chart below.
On the x-axis are different types of windows and on the y-axis, the average cost of repairing them in US dollars for the past year. As indicated by the colors, quotes vary between domestic vehicles, foreign vehicles, and luxury. Windshield Replacements for 2014 Infiniti Q50 4 Door Sedan were the most expensive type of auto glass repair overall in Saddle Brook, New Jersey, which typically costed an average of US$453.67 in the past year.
Curious about how much other Glass.Net customers are paying for auto glass repair in Saddle Brook, New Jersey?
Below are some recent auto glass repair and replacement price quotes for Saddle Brook, New Jersey via Glass.Net. These estimates have been given to customers in your area from local car glass repair shops, for their specific vehicles and auto glass damage. This includes car side window repairs ("Door"), front windshield and rear window.
Vladimire was very polite, professional, clean, and did an amazing job. Would recommend this company to anybody.
Everything went well and the job was done perfectly. I did have to clean my door sils and dash which could be expected but I feel could have been avoided. Overall thumbs up.
The windshield looks amazing. I have experienced other people getting their windshields replaced and not getting the best service. So the exceptional service is greatly appreciated!Thank you again!


text:
A Night of Stand Up Ft. Jessimae Peluso and Carly Aquilino
/ticket/p/5284002/a-night-of-stand-up-ftjessimae-peluso-and-carly-aquilino--nashville-zanies-comedy-club 04-10-2022 22:15:00 04-10-2022 22:15:00 A Night of Stand Up Ft. Jessimae Peluso and Carly Aquilino Zanies Comedy Club true MM/DD/YYYY
GENERAL ADMISSION Public Onsale: December 2, 2021 3:48 PM to April 10, 2022 9:15 PM
Carly Aquilino and Jessimae Peluso are best friends and hilarious comedians, also.
Most were introduced to the duo by the way of MTV's hit show Girl Code. Since then, they've been seen and heard on Comedy Central, Kevin Hart's Laugh Out Loud Network and so, so many hit podcasts. Jessimae enjoys a good toke and Carly has a thing for ant farms. They are marvels.
Together they host (the brand new!) GYRL. A podcast with real life best friends, giving you real life advice on f**kboys, adult toys, and what it means to live your most authentic self. Yes! Bless.
More about Carly Aquilino and Jessimae Peluso.
Carly was recently seen in Judd Apatow's The King of Staten Island. Her wit and sarcastic humor has been showcased on several MTV shows and specials—including the network's famed Video Music Awards Red Carpet Pre-Show, Comedy Central, TV Land, and in comedy clubs all across the nation. She has performed at military bases overseas for the USO – and has been featured on Gotham Comedy Live and performed on Kevin Hart's Laugh Out Loud Network from the legendary Montreal Comedy Festival.
Jessimae made her Netflix debut as host of Tattoo Redo. She has delivered her high-energy wit, comedy and charm for U.S. troops overseas and on Lights Out with David Spade, VH1's Hip Hop Squares, Comedy Knockout, The Funny Dance Show, Doug Benson's Getting Doug with High, Andrew Santino's Whiskey Ginger. She has made several appearances on The Joe Rogan Experience and has performed at the prestigious Just For Laughs festival and the Moontower Comedy Festival.


text:
Q: The Less command can list directory contents in Gentoo Linux, but not in Ubuntu Linux I regularly use the 'less' command in Gentoo like so:
less /tmp
(or any other directory, which I have access to.)
Less then proceeds to show me the contents of that directory. I can also use Less to show the contents of files (the usual use case).
In Ubuntu (Oneiric) when executing the above command, Less reports:
/tmp is a directory
Less will not list the contents of the directory.
I am using Less version 444 in both operating systems.
Can anyone help? I have been unsuccessful searching online.
Thanks in advance.

A: Lesspipe is part of the less package on Ubuntu (Precise, at least), and is probably already installed on your computer.
Put this command in a login script, for instance ~/.bash_login:
eval $(lesspipe)

Then put this content in ~/.lessfilter
#!/bin/sh

# show directory as listing
if test -d "$1"; then
 /bin/ls -alF -- "$1"

 # we handled this one ourself
 exit 0
fi

# handle by regular lesspipe
exit 1

And make this file executable:
chmod +x ~/.lessfilter

Directories should now be shown as long format listings.

A: Check out the README.gentoo file in
/usr/portage/sys-apps/less/files

The behavior of less is customized by a lesspipe.sh script (in that same directory). If the argument passed is a directory, lesspipe.sh does ls -alF on it and that is what less pages.
See the less man page, Input preprocessor section for additional information. You can probably pick up Gentoo's lesspipe.sh and put it on your Ubuntu system without much hassle.

redpajama_set_name: RedPajamaStackExchange


How many dimes are in 80 quarters?
Here, we will show you how to calculate how many dimes there are in 80 quarters.
First, calculate how many cents there are in 80 quarters by multiplying 80 by 25, and then divide that result by 10 cents to get the answer.
Note: We multiplied 80 by 25, because there are 25 cents in a quarter, and we divided 2,000 by 10, because there are 10 cents in a dime.
How many dimes are in 82 quarters?


text:
Try Escape from Tarkov, the most realistic and brutal FPS simulator game currently available
Image via Battlestate Games
Escape from Tarkov is one of the most difficult and unforgiving first-person action RPG/Simulator games currently available, and that makes it strangely enjoyable.
Escape from Tarkov is a hardcore and realistic online first-person action RPG/Simulator with MMO features and a story-driven walkthrough. It is a small-scale venture where small groups of players go on raids for materials, fighting with other groups over the finite resources available on each map.
Players can load in with any gear they won in previous games, but they run the risk of losing it all on death.
There will be a video on the .338 at 5am PST! f's for dave #escapefromtarkov pic.twitter.com/A9oT0uvHGW
— Anton (@AntonFromYT) January 1, 2021
What is Escape from Tarkov?
Escape from Tarkov entered a period of closed beta in mid-2017, and has mostly flown under the radar since then. The game is produced by developer Battlestate Games and is set in a fictional region in Russia. The core selling point of the game is its incredible number of ways to control the character, giving players an unparalleled level of realistic movements.
Escape from Tarkov features a variable walk speed, as well as eight different body positions ranging from standing to lying prone. The weapons in Escape from Tarkov can be almost totally disassembled and customized with parts gathered through the game.
Even something as simple as reloading has a realistic flair, with reloads normally having the player character place the removed magazine back into their inventory, while fast reloads have them just drop the magazine on the ground instead. In many ways, it's more like the Day Z than the more streamlined and simplified shooters that followed.
Escape from Tarkov has an incredible amount of depth and precision, and will almost certainly not be for everyone. Nevertheless, the game has managed to earn a sizable core following, and recently peaked at over 400,000 viewers watching the game on Twitch.
Who might enjoy Escape from Tarkov?
Anytime I raid with @JawshPawshTV there's always some shenanigans 😂#EscapefromTarkov @bstategames pic.twitter.com/ZW9u6oalnB
— DottyHack (@DottyHackTV) January 5, 2021
Everyone has the ability to enjoy Escape from Tarkov, whether playing it or just watching it on stream. However, the game certainly does appeal to a specific type of player.
Anyone who likes games that offer a challenge, isn't afraid of losing, and enjoys playing high-tension games that keep them on the edge of their seat will almost certainly want to give this one a try.
Escape from Tarkov tends to appeal to players who have played other highly realistic shooters, such as ARMA, Red Orchestra, or The Hunt: Showdown.
Players who enjoy highly challenging games, such as almost anything made by From Software (Dark Souls, Sekiro), may also consider checking it out. They may find that Escape from Tarkov features the same thrilling-yet-terrifying gameplay common to those kinds of games.
Escape from Tarkov currently has a player count of over 200,000, and almost twice as many people watching the game on Twitch. If the game continues to grow like that, it could very well put hardcore shooters front and center for many gamers.


text:
Q: Яндекс Диск. API - загрузка файлов Пытаюсь отправить файл с формы на облако Яндекс диска. Я понимаю, о чём ошибка, но не понимаю, как исправить. Мне не нужно загружать файл сначала на свой сервер, а с него на Яндекс, нужно сразу с устройства юзера на Яндекс, как это и задумано изначально.
Форма:
<form method="post" action="file.php" enctype="multipart/form-data">
    <input type="hidden" name="MAX_FILE_SIZE" value="30000" />
    <input name="ff" type="file">
    <input type="submit" value="отправить" name="uploadBtn">
</form>

PHP:
$token = 'TOKEN';

// Путь и имя файла на нашем сервере.
$fileName = $_FILES['ff']['name'];
$fileNameCmps = explode(".", $fileName);
$fileExtension = strtolower(end($fileNameCmps));
$file = md5(time() . $fileName) . '.' . $fileExtension;

echo $file;

// Папка на Яндекс Диске (уже должна быть создана).
$path = '/test/';

// Запрашиваем URL для загрузки.
$ch = curl_init('https://cloud-api.yandex.net/v1/disk/resources/upload?path=' . urlencode($path . basename($file)));
curl_setopt($ch, CURLOPT_HTTPHEADER, array('Authorization: OAuth ' . $token));
curl_setopt($ch, CURLOPT_RETURNTRANSFER, true);
curl_setopt($ch, CURLOPT_SSL_VERIFYPEER, false);
curl_setopt($ch, CURLOPT_HEADER, false);
$res = curl_exec($ch);
curl_close($ch);

$res = json_decode($res, true);
if (empty($res['error'])) {
// Если ошибки нет, то отправляем файл на полученный URL.
    $fp = fopen($file, 'r');

    $ch = curl_init($res['href']);
    curl_setopt($ch, CURLOPT_PUT, true);
    curl_setopt($ch, CURLOPT_UPLOAD, true);
    curl_setopt($ch, CURLOPT_INFILESIZE, filesize($file));
    curl_setopt($ch, CURLOPT_INFILE, $fp);
    curl_setopt($ch, CURLOPT_RETURNTRANSFER, true);
    curl_setopt($ch, CURLOPT_SSL_VERIFYPEER, false);
    curl_setopt($ch, CURLOPT_HEADER, false);
    curl_exec($ch);
    $http_code = curl_getinfo($ch, CURLINFO_HTTP_CODE);
    curl_close($ch);

    if ($http_code == 201) {
        echo 'Файл успешно загружен.';
    } else {
    echo 'error2';

    }
}  else {
    var_dump($res['error']);
}

В итоге я получаю такой ответ

Файл появялется на диске, но он некорректный, его нельзя открыть и посмотреть, но название, расширение передаются. Размер 0

A: Файл получай из формы $fp = file_get_contents($_FILES['file']['tmp_name']);
и curl для записи используйте такой. Проверено, работает.
Форма:
<form method="post" action="yandex-file.php" enctype="multipart/form-data">
<input name="file" type="file">
<input type="submit" value="отправить" name="uploadBtn">
</form>

PHP:
if (empty($res['error'])) {

    $fp = file_get_contents($_FILES['file']['tmp_name']);

    $ch = curl_init();
    curl_setopt($ch, CURLOPT_URL, $res['href']);
    curl_setopt($ch, CURLOPT_CUSTOMREQUEST, 'PUT');
    curl_setopt($ch, CURLOPT_POSTFIELDS, $fp);
    $answer = curl_exec($ch);
    $http_code = curl_getinfo($ch, CURLINFO_HTTP_CODE);
    curl_close($ch);

    if ($http_code == 201) {
        echo 'Файл успешно загружен.';
    } else {
        echo 'error2';

    }
}  else {
    var_dump($res['error']);
}


There is a standardized format of writing Torah scrolls called Vavei Ha'amudim. The concept is that the majority of columns in the Torah (except for 6 places) should start with the letter vav.
This answer gives a bit more detail on why this format was done as well as its controversy. However, it seems that the concept is to create Sifrei Torah to match Davidovich's Tikkun format.
Considering that the main requirement to conform to the format is that the letter vav appears at the top of the column. Considering that almost every verb usage in the Torah has a vav hahipuch, it's not hard to do this.
Are all Vavei Ha'amudim Sifrei Torah that were created after Davidovich's latest standard identical? If not, how many current Sofrim (approximate percentage is fine) these days are using Davidovich's format as opposed to just creating any other Vavei Ha'amudim standard?
Whether those 2 are identical I cannot say.


Sol [sool]: sun in Swedish Combining our smart and stylish design with beach cruiser comfort, the Sol is one of the lowest step-through electric cruisers available. Whether you're ready to get on a bike again, looking for a laid-back ride around the neighborhood or simply want a bike that is super easy to get on and off—the Sol is for you. Take a ride. Cruise In Comfort Laid-back, relaxed riding comes naturally with the Sol. Sitting on 27.5" wheels and comfortable 2.2" tires, you'll glide effortlessly over pavement and hard-packed trails. Equipped with wide, swept-back handlebars and a wide seat, you will experience the most comfortable and natural fit while riding. Go low, ride with confidence. The sleek curves of its super low single downtube makes it incredibly easy for any rider to mount and dismount regardless of flexibility, mobility or confidence levels. User Friendly Design The Sol's 7-speed Shimano twist shifter is intuitive for any level of rider. Mechanical disc-brakes with automatic motor cutoff keep speed in check, and the stay-mounted kickstand offers stable parking anywhere without interfering with the cranks. Smart Battery Design To optimize riding experience, the battery is placed low under the rider's weight to provide an even weight distribution and a very low center of gravity. The result: a stable, sturdy and pleasant riding experience. To charge the battery, simply plug it into a standard wall outlet, either off or on the bike — the seat flips up for easy access if you choose to remove! You can also lock the battery to the frame with the provided key. Isn't it nice when things are easy?
When Benno made a Ballooner prototype a few years ago, they found that they enjoyed riding it more than any other bike. The very balanced geometry is comfortable and sporty, which allows for a longer, more purposeful ride. Elevated specs, including Tektro rim brakes and 8-speeds, provide a smooth, almost effortless riding experience. The big, plush tires provide a comfortable and controlled ride. Studies have proven that in many road conditions quality high volume tires actually have less rolling resistance than skinny tires. In most urban settings, you'll often find yourself on rougher, less than perfect roads – another situation made better by a wider tire. All in all, the Ballooner is a real gentleman: humble, polite, elegant and extremely capable. A modern retro-style everyday commuter.


text:
'That '70s Show' Actress and Bond Girl Tanya Roberts Has Died (UPDATE)
UPDATED 1/5, 9:45 a.m. ET: Roberts died on Monday night at the Cedars-Sinai Hospital in L.A. Her partner Lance O'Brien—initially part of the confusion surrounding premature reports of her passing—told TMZ a doctor phoned him on Monday night to tell him she had died.
UPDATED 1/4, 5:22 p.m. ET: Tanya Roberts has not died, TMZ reports. News of the actress' purported death was reported on after Mike Pingel, Roberts' rep, incorrectly announced that she passed away at 65.
Pingel previously announced that Roberts died at Cedars-Sinai Medical Center on Sunday and that he was told by her husband, who claimed that his partner "died in my arms." The rep told TMZ that he received a call on Monday from Lance, who's Tanya's husband, saying that she is still alive.
See original story below.
Actress Tanya Roberts, best known for her roles in the James Bond film A View to a Kill and That '70s Show, has passed away.
According to TMZ, the former bond girl collapsed at home on Christmas Eve after taking her dogs out for a walk. The 65-year-old died on Sunday, Jan. 3, after being taken to the hospital and put on a ventilator. Sources told TMZ her death was not COVID-19 related, and Roberts was reportedly healthy leading up to her death.
At the height of her career in the '70s and '80s, Roberts worked as an actress starring in campy adventure films like 1979's Racquet, '82's The Beastmaster, '84's Sheena: Queen of the Jungle, and '86's Body Slam, many of which would develop cult followings that still exist today.
She eventually took the coveted role as Bond girl Stacey Sutton in A View to a Kill, starring alongside 007 actor Roger Moore. In the film Roberts portrays the American geologist who becomes a target of Bond villain Max Zorin, played by Christopher Walken.
Roberts also hit the small screen, most notably as Donna's mother Midge Pinciotti in the comedy series That '70s Show. After playing Midge for three seasons, Roberts temporarily left the show to care for her ill husband, the late Barry Roberts. She later returned to play the character for the sixth and seventh seasons.
Tanya, who was born in the born in the Bronx as Victoria Leigh Blum, also had a successful modeling career. She landed a Playboy cover in 1982 and starred in a number of commercial TV ads.
Per the Hollywood Reporter, Tanya is survived by partner Lance O'Brien and her sister Barbara Chase. RIP.
Larry King Reportedly Leaves ICU After COVID-19 Treatment (UPDATE)
Study Finds That Women Directed a Record Number of Films in 2020
News70sJames BondRIPSitcomsActress


PUPPY TALES is back with a special Thanksgiving episode! Travel along with Andreas Wyder, currently starring as "Young Max" in the 2014 National Tour of How The Grinch Stole Christmas: The Musical, and get a backstage peek at life on the GRINCH National Tour in Episode 6 of PUPPY TALES, a backstage video blog. Click below!
THE GRINCH 2014 National Tour stars Stefan Karl as The Grinch, Andreas Wyder as Young Max, Bob Lauder as Old Max, and Raleigh Shuck/Aviva Winick as Cindy Lou Who.
For more about the show, visit www.grinchmusical.com, and for more about Wyder, go to www.andreaswyder.com.


This special collaboration between DLK and the local Philadelphia based designer shines light on the love of the everyday and our modern aesthetic. Box sets include 4 designs and 8 cards and comes in a beautiful matte black box with a clear lid. Just want one? They're sold separately as well.


If minimal, electronic, sega/nintendo sounding music is your thing chances are you will love Irvine, California's Ice Cream Social. Sam the man behind ICS sent over his latest single/EP 'Positron' and I'm digging it! The 3 tracks all run under 2 mins and combined are probably shorter than most single tracks, but one thing's for sure they will have you pressing repeat many times. Check out/dl "Positron" and "Terra Nova" below. Grab more free goodies on his bandcamp.


Vedanta Biosciences, a clinical-stage company developing a new category of therapies for immune-mediated diseases based on rationally-defined consortia of human microbiome-derived bacteria, announced preclinical data for VE800, the Company's orally-administered, live biotherapeutic product candidate in immuno-oncology.
The study showed that VE800 elicited an anti-tumor immune response as a monotherapy and also enhanced effects of immune checkpoint inhibitors. Additionally, the results describe a mechanism of action for VE800 as the robust interferon-gamma producing CD8+ (cytotoxic) T cell response was elicited via activation of dendritic cells. The data will be presented at the Society for Immunotherapy of Cancer's (SITC) 33rd Annual Meeting by Dr. Bruce Roberts, Chief Scientific Officer of Vedanta Biosciences, on November 8. Vedanta Biosciences expects to initiate a clinical study of VE800 in mid-2019.
said Bruce Roberts, Ph.D., Chief Scientific Officer of Vedanta Biosciences.


text:
Q: GLKView won't change pixel format There is an issue of GLKView, I'm stuck here a lot. First, I create EAGLContext context and make it current:
EAGLContext* pOpenGLContext = [[EAGLContext alloc] initWithAPI:kEAGLRenderingAPIOpenGLES3];
if(!pOpenGLContext)
    return nil;
if(![EAGLContext setCurrentContext:pOpenGLContext])
    return nil;

Runs ok (I need version 3 so it sutes me)! Then I create GLKView, attached to previously created context:
GLKView* pOpenGLView = [[GLKView alloc] initWithFrame:Frame context:pOpenGLContext];

It's ok. But this code don't change anything at all :(
[pOpenGLView setDrawableColorFormat:GLKViewDrawableColorFormatRGBA8888];
[pOpenGLView setDrawableDepthFormat:GLKViewDrawableDepthFormat24];
[pOpenGLView setDrawableStencilFormat:GLKViewDrawableStencilFormatNone];
[pOpenGLView setDrawableMultisample:GLKViewDrawableMultisampleNone];

Then I do some final stuff:
pOpenGLView.delegate = self;
[pMainWindow addSubview:pOpenGLView];
...

However, after using GLKViewDrawableStencilFormatNone, I asks OpenGL for a depth and stencil formats... I get:
glGetIntegerv(GL_DEPTH_BITS, &OpenGLDepthBits);      // = 32 (I need 24)
glGetIntegerv(GL_STENCIL_BITS, &OpenGLStencilBits);  // =  8 (I need 0)

I need to turn stencil buffer off! I need to set 24-bit format depth buffer.
I have try to do like this also:
pOpenGLView.drawableColorFormat = GLKViewDrawableColorFormatRGBA8888;
pOpenGLView.drawableDepthFormat = GLKViewDrawableDepthFormat24;
pOpenGLView.drawableStencilFormat = GLKViewDrawableStencilFormatNone;

How can I get it? What is wrong here? Thank you.


Submitting a new Mac application to a popular software tracking website (Download.com, MacUpdate, Softpedia...) sounds easy. It maybe is if you assume that nothing goes wrong on their side. The fact is that you can end up getting redirected to an empty page because of their website's server error. Sometimes, your web browser can quit itself all of a sudden, losing all the progress you've made. Sometimes, their website is inaccessible when you want to submit a new software update. On the other hand, one common mistake that you can make on your side is to give them a URL as a file location that does not exist. Anyhow, you'd better keep an eye to their website's software list for the next several hours because, whatever the reason is, there is no guarantee that they will list your software submission. Well, the best you can do is to make sure that the file path is correct. And... Wait, when did you submit your software update?
VersionsX is a software title that is designed to help developers document version history for any number of software titles. Every time you create a new software version profile, VersionsX can access the given URL constantly to see if the software file you designate is accessible. Don't worry about tagging each line with <li> when you write software changes because VersionsX can do it when you generate a software update summary.
Check and see if a given URL is accessible in real time (every several seconds).
Automatically, count the numbers of letters and words for software short/long descriptions.
Six date formats to choose from for international differences.
Click on the clock-in button to record the time when you actually submitted a software update for a particular software version.
Click on the button to download a beta/demo/trial version of VersionsX for Mac OS X 10.5 and 10.6.
The user can drag and drop an application (icon) directly onto VersionsX. If it's an existing application, then VersionsX will automatically sets the application drop-down menu accordingly. If it's a new application, then VersionsX will get ready to register a new application.
The application will check the available resolution of the computer used by the user. If it doesn't meet the minimum resolution set by the application, the user will be prompted with a confirmation dialog.
The user has an option of letting the Info window follow the main window. See Preferences. Enable the checkbox labeled Follow by Info to let the Info window follow the main window.
If the user has not set the default web browser, clicking on the Show button on the main window will prompt a message.
A dozen other minor changes and fixes are made.
Numerous changes are made in order to make the application compatible with Mac App Store requirements.
Fix: When the user opened Preferences while the main window is out of Desktop coordinates, they could not close the Preferences window.
Change: The user no longer has to wait for one second in quitting the application.
Change: A checkbox is removed on the main window. Instead, a new toolbar button is installed for opening software information.
The user interface has changed as a whole a little on the main window.
Fix: The application could hang up if the user enabled 'URL Verification' under Settings2 in Preferences.
URL verification's time interval is revised to 3 seconds. It was 1.5 seconds.
Fix: The user was not able to create or revise accounts under the Web tab.
Change: The vertical scrollbar is removed from all multi-line text area controls as they it can partially break the window user interface.
Fix: The default web browser that the user may have selected in Preferences was not utilized with all web buttons.
Preferences: Additional options are added under Settings2.
A dozen other minor changes and fixes are done.
When the user publishes a software update, the application will automatically check the connectivity of three URLs. (Developer site, Web site and Download URL) If any of them is not accessible, the corresponding 'check accessibility' button will have an 'inaccessible' picture on it.
The user can now run a search to find an application to work on.
The user can now save changes while publishing a software update. Go to File > Save.
Several other changes are made. For example, see what's added under the Settings2 tab in Preferences.
Fix: The position of the main window was not saved when the user closed Preferences.
Change: The developer information (Preferences > Developer) is saved in a database for reliability. This information must be filled again because of this change.
Preferences: The user can set their default web browser used with this application under the System files tab.
Clicking on the Show button on the main window, the application will launch user-defined web browser to see version changes.
Fix: Clicking on the Show button after exporting a graphic file, the application did not open the folder containing the file.
Fix: A rescaled picture was not available for PNG images on the export window.
The application will regenerate missing application files if there are at the time of startup.
Several more help tags are added.
The Download button is now available for each version.
When the user publishes a version release, they can enclose the long description with <p>.
The price field is now available when the user creates a new software profile.
The system requirements field is now available when the user creates a new software profile.
The Show button is now available for each version. Clicking on it, the user is able to view software changes with an HTML window.
The user is able to enclose software version changes with <li> and <ol>.
When the user publishes a software version, the Connect button is now available, allowing them to check the accessibility of the download URL.
Other numerous major/minor fixes and improvements are made.
VersionsX is a product of MacHouse.


text:
Editorial and content
Website design and build
Five things brands learnt about video content from Covid-19
22nd Jun 2021
It's not surprising that at the height of lockdown consumers engaged with 80% more digital content than usual. Being cooped up inside for months un-end, video whether it was Netflix, social media or good old-fashioned TV became not only our favourite way to pass the time, it served as a memento of better days. Giving hope that things would improve.
Of course, no industry was left unaffected by the global pandemic and while the demand for video skyrocketed, COVID threw a spanner in the works when it came to its production. With Government advice being that everyone should remain indoors as much as possible. How did producers get around these hurdles and how did their output change?
1. Animated times
The most obvious solution to creating engaging video, in a period when encouraging workers to leave their home was unadvisable was of course with animation. While there are certain constraints when it comes to animating from home — such as the need to transport bulky equipment to people's homes, and the limitations of domestic internet connections. For the most part, animation can be done as easily from home as it can in the studio.
For this reason, there was a surge in animated corporate videos and advertisements, The government itself lead by example with a series of animated videos on test and trace.
2. Brands learnt to recycle, finally!
Recycling is a hot topic in the modern age, we are all aware that we need to individually take steps to tackle our 'throwaway culture' to reduce plastic waste and help save the environment. It is strange then that many brands still maintain a throwaway mentality when it comes to their content. We always advise clients to keep reposting video content even if it was made years before.
At the end of the day, video is a cost-intensive medium and it makes no sense to only promote content a few times on release to be forgotten about. Recycling content should be a key component of any brand's marketing strategy.
The power of recycling was it seems, finally discovered by many over lockdown. We saw a surge in brands reposting their older video throughout this period as the combination of covid-19 restrictions and staff furlough prevented the creation of new video.
One word of warning: ensure your content is evergreen, re-watch everything the whole way through before you repost. You must ensure there is nothing that will make the video seem anachronistic, such as references to an expired date.
3. Brands embraced their archive
We all know that video files are BIG, just one hour of 4k footage takes up a colossal 318 GB of storage space. This can give us all the temptation to jettison rushes after a project has been completed, to reduce external HDD costs or our cloud storage solutions.
However, this is incredibly foolhardy. Hours of footage might be recorded to make a video that lasts just a couple of minutes, and this is ripe for repurposing. It was the brands and agencies that maintain a well-organised archive of all their footage that reaped the most benefit this year — being able to turn old footage into shiny new video output.
4. Brands wanted to sound kinder
Perhaps the biggest change we saw in 2020 was the change in brands' tone of voice. Understandably in such frightening times, brands wanted to sound fuzzier, kinder and comforting, this wasn't the time for the hard-sell it was time to take a far softer approach. This is perhaps best illustrated by Unilever's Domestos campaign which used the line 'use bleach, any bleach' when cleaning the home to reduce the risk of Covid-19.
5. Brands took a low-fi approach
To great success, a large proportion of brands embraced the low-fi trend when it came to their production. Perhaps in the same way that office dress codes became slacker while people worked from home, we also became more accepting of the 'rough and ready' aesthetic when it came to content.
Perhaps the earliest pioneer of this was Dominos, who in the US created an advertisement entirely using zoom.
Want to find out about incorporating video successfully into your marketing strategy? Get in touch.
Vivid Content Marketing Ltd
6 King Street
Bristol, BS1 4EQ
Email hello@vividimagination.studio
Registered number: 09274069. © 2022 Vivid Content Marketing Ltd.


Targeting Cdc7, a kinase essential for DNA replication initiation, results in potent cancer cell killing. Cancer cells in which CDC7 is silenced by RNAi enter an abortive S phase followed by apoptosis due to loss of a functioning DNA replication origin activation checkpoint. This checkpoint prevents normal cells from entering S phase (reversible G1 arrest) if the DNA replication initiation machinery is perturbed. The pre-clinical anti-cancer effects of CDC7 silencing have highlighted this kinase as an important target for new drug development. Expanding on published reports, I performed further target validation using molecular tools generated in the work of this thesis, including an affinity-purified antibody to the Cdc7 regulator ASK and functional recombinant Cdc7/ASK kinase complex. Making use of fibroblast and HL60 tissue culture model systems, I show that Cdc7 and ASK are amongst a group of essential replication initiation factors that are tightly downregulated to suppress proliferative capacity during exit from cycle into quiescent and differentiated states. This finding is further supported by low expression levels in normal liver and oral squamous epithelium and the lack of Mcm2 phosphorylation at serine 53, a well known Cdc7 target. In liver carcinoma and oral squamous cell carcinoma, on the contrary, the majority of cancer cells are expressing Cdc7 and ASK and show Mcm2 phosphorylation at Ser-53. Thus it can be postulated that Cdc7 inhibitors should selectively kill cancer cells, while normal proliferating cells are reversibly arresting in G1 and quiescent and differentiated cell populations are not affected due to downregulation of the target protein. To screen for compounds that selectively inhibit Cdc7, I developed a sensitive in vitro kinase assay and contributed to the successful transfer of this assay to a high-throughput screening platform and the generation of a structural model of the Cdc7 kinase domain allowing in silico predictions of the most potent inhibitors. On completion of the work for this thesis, the HTS assay and structural model fromed the core of an ongoing drug discovery programme run by Cancer Research Technology. Two series of novel, selective small molecule inhibitors which exhibit low nM activity against Cdc7 and cellular efficacy (apoptosis) have been developed and are currently being tested in mouse xenograft models. The work presented in this thesis provides a strong rationale for targeting the DNA replication initiation pathway, and in particular Cdc7. Future intend to treat clinical trials will establish the potential of pharmacological Cdc7 inhibitors for selective cancer cell killing in patients.
Copyright restricted material comprising of published articles in appendices D, E and F has been removed from the e-thesis.


text:
"When one plays a Steinway, there is a warmth and nobility in the sound that is unequalled by any other instrument."
Born in Lviv, Ukraine, Emanuel Ax showed an early talent and interest for music — studying violin and taking piano lessons with his father, who was a coach at the city opera house. He studied at Juilliard after his family moved to New York, and after disappointing finishes in high-profile events like the Chopin Competition and the Queen Elizabeth Competition, Ax withdrew from competing for a time to make his 1973 New York debut, at Alice Tully Hall. The year after, he won the Rubinstein Piano Master Competition, and made his name in the American concert tour included with the success. In 1979 he was awarded the coveted Avery Fisher Prize, which led to a recording contract with RCA Victor.
As a soloist, Ax has demonstrated a particular affinity for the Romantics; nonetheless, his repertoire is among the most diverse of any pianist on the scene today and ranges from the music of Haydn, Mozart, and Beethoven to important twentieth century figures like Tippett, Henze, and Hindemith. He is considered by players and audiences alike to be a chamber musician par excellence; his frequent partners in this endeavor include Isaac Stern and Yo-Yo Ma — with whom he has netted three Grammy awards. Ax has also demonstrated an interest in historical performance; he recorded Chopin concerti on a period instrument similar to Chopin's own. He maintains a busy recording and recital schedule and frequently appears with the world's leading orchestras and at the major music festivals.
Ax has been a Steinway Artist since 1981.


text:
using GraphQL.Validation.Errors;
using GraphQL.Validation.Rules;

namespace GraphQL.Tests.Validation;

public class UniqueOperationNamesTests : ValidationTestBase<UniqueOperationNames, ValidationSchema>
{
    [Fact]
    public void no_operations()
    {
        ShouldPassRule("""
                fragment fragA on Type {
                  field
                }
                """);
    }

    [Fact]
    public void one_anon_operation()
    {
        ShouldPassRule("""
                {
                  field
                }
                """);
    }

    [Fact]
    public void one_named_operation()
    {
        ShouldPassRule("""
                query Foo {
                  field
                }
                """);
    }

    [Fact]
    public void multiple_operations()
    {
        ShouldPassRule("""
                query Foo {
                  field
                }

                query Bar {
                  field
                }
                """);
    }

    [Fact]
    public void multiple_operations_of_different_types()
    {
        ShouldPassRule("""
                query Foo {
                  field
                }

                mutation Bar {
                  field
                }

                subscription Baz {
                  field
                }
                """);
    }

    [Fact]
    public void fragment_and_operation_named_the_same()
    {
        ShouldPassRule("""
                query Foo {
                  ...Foo
                }

                fragment Foo on Type {
                  field
                }
                """);
    }

    [Fact]
    public void multiple_operations_of_same_name()
    {
        var query = """
                query Foo {
                  fieldA
                }

                query Foo {
                  fieldB
                }
                """;

        ShouldFailRule(_ =>
        {
            _.Query = query;
            _.Error(UniqueOperationNamesError.DuplicateOperationNameMessage("Foo"), 5, 1);
        });
    }

    [Fact]
    public void multiple_operations_of_same_name_of_different_types_mutation()
    {
        var query = """
                query Foo {
                  fieldA
                }

                mutation Foo {
                  fieldB
                }
                """;

        ShouldFailRule(_ =>
        {
            _.Query = query;
            _.Error(UniqueOperationNamesError.DuplicateOperationNameMessage("Foo"), 5, 1);
        });
    }

    [Fact]
    public void multiple_operations_of_same_name_of_different_types_subscription()
    {
        var query = """
                query Foo {
                  fieldA
                }

                subscription Foo {
                  fieldB
                }
                """;

        ShouldFailRule(_ =>
        {
            _.Query = query;
            _.Error(UniqueOperationNamesError.DuplicateOperationNameMessage("Foo"), 5, 1);
        });
    }
}

redpajama_set_name: RedPajamaGithub


text:
Ex-F1 driver Petrov joins SMP Racing for 2016 WEC season
By Luke SmithDec 26, 2015, 10:30 AM EST
Former Formula 1 driver Vitaly Petrov will move into the FIA World Endurance Championship next season with SMP Racing in the LMP2 class.
Petrov raced for Renault and Caterham in F1 between 2010 and 2012, becoming the first Russian driver to race in the series and recording a best finish of third in the 2011 Australian Grand Prix.
After taking a year out of racing in 2013, Petrov moved into DTM with Mercedes for 2014, but failed to score any points.
Now, the Russian will prepare to make his WEC debut with SMP Racing, which will expand its involvement in the LMP2 class of the championship with its BR Engineering cars in 2016.
SMP Racing unveiled Petrov at its end of year press conference in Russia earlier this week, confirming that he will race one of two LMP2 cars to be entered into the WEC.
It also announced that Petrov will be joining its development programme that looks to help young Russian drivers move up the motorsport ladder.
"Friends! I want to tell you the news – I will spend 2016 with SMP Racing in the FIA World Endurance Championship!" Petrov wrote on Instagram.
"I want to personally thank Boris Romanovich Rothenberg for giving me the opportunity to fly the Russian flag in the famous 24 Hours of Le Mans race."
Petrov's arrival on SMP Racing's endurance programme follows Mikhail Aleshin's return to IndyCar for 2016, when he will race for Schmidt Peterson Motorsports.
Petrov may not have raced in the WEC before, but he has one previous appearance at Le Mans, taking part in the 2007 race for Noël del Bello Racing.
Follow @LukeSmithF1


text:
var path = require('path');
var webpack = require('webpack');
var _ = require('lodash');

var baseConfig = require('./base');

var config = _.merge({
    entry: path.join(__dirname, '../src/index'),
    cache: false,
    devtool: 'sourcemap',
    plugins: [
        new webpack.optimize.DedupePlugin(),
        new webpack.optimize.UglifyJsPlugin(),
        new webpack.optimize.OccurenceOrderPlugin(),
        new webpack.optimize.AggressiveMergingPlugin(),
        new webpack.NoErrorsPlugin()
    ]
}, baseConfig);

module.exports = config;


text:
Монсуе́ () — муніципалітет у Франції, у регіоні Нова Аквітанія, департамент Ланди. Населення —  осіб (2011).

Муніципалітет розташований на відстані близько 610 км на південь від Парижа, 125 км на південь від Бордо, 18 км на південь від Мон-де-Марсана.

Демографія

Розподіл населення за віком та статтю (2006):

Економіка

У 2010 році в муніципалітеті числилось 217 оподаткованих домогосподарств, у яких проживали 564,0 особи, медіана доходів виносила  євро на одного особоспоживача

Посилання

 Офіційний сайт Монсуе
 [ Розташування муніципалітету Монсуе на мапі Франції та сусідні муніципалітети]

Див. також
 Список муніципалітетів департаменту Ланди

Примітки

Муніципалітети департаменту Ланди


text:
One Stop Shop Abroad
Development / Design / CMS / Consulting
We were called in to design a website for One Stop Shop Abroad (OSSA), a ground floor company that shipped goods from the USA to countries all over the world. They wanted a lightweight site that was easy to navigate and clear to see what the company was about and also to simple to use.
We decided to go with a custom built CMS, which allowed OSSA to keep control of the registered users and recently purchased items. The colours of the website were based on the logo that already existed for OSSA. The orange, blue and red can be seen all throughout the website, creating a homogeneous look and feel.
Nidogas Nigeria
Development / Consulting
Nidogas Nigeria is a large and reputable petroleum gas company that are based in Nigeria. For this project we worked closely with the designer from conception to completion of the website. We are extremely happy with the completed website as when you visit the Nidogas website you are immediately pulled in with the colours and the slideshow and the easy to navigate layout.
We integrated a news feed into the site from a large online African news company. The news feed features up to date information about the petroleum industry in Africa and allows users to quickly access the news article. We felt this was a great addition to the website as it was relevant and was added value to customers who would be visiting the website.
We also created an area for feedback for customers to tell Nidogas what they think about the website etc. The majority of Nigerian companies do not put too much emphasis on their websites, so as this was a new and uncertain venture for their company they wanted to see how their customers perceived the site.
Phil Schneider Music
Development / Design / Consulting / CMS
Phil Schneider is a musician from Central Florida and has been in the industry for 30+ years. Phil already had a website, but needed an upgrade to modernise the website. After working on a few designs with Phil and tweaking the final product we decided on a design that featured lots of photos of Phil up close and links that allowed his fans to buy CD's quickly and easily.
Phil also requested an Events page that allowed fans to see where he would be playing next. For this section we created a custom CMS that allowed Phil to add, edit and delete events from the website.
Neneh & Odiri
Development / Design / Consulting / Flash
This was one of our more fun websites to work on. This was our first full flash website and it was for Elizabeth Maduka's sister's wedding. Take a look for yourselves at the finished product.
Adzo Jewellery
Adzo Jewellery (Adzo) are a London based bespoke jewellery company that needed an ecommerce website built, so they could start to sell their jewellery online. We decided to go with the OScommerce shopping basket, because of the in-built security and the ability to accept payments from all over the world already incorporated in the shopping basket software.
The green theme on the site was based on the colour of a particular piece of jewellery that Adzo had available for sell. The unique piece about this website is that Adzo wanted to keep the look and feel of the shopping section and the other sections separate. They wanted a clear differentiation between the two, hence why you see the two different styles on website.


text:
Home » S&P upgrades Reliance Ind's long-term credit rating
Published On : Wed, May 29th, 2013
Business News | By Nagpur Today Nagpur News
S&P upgrades Reliance Ind's long-term credit rating
Nagpur News: Leading rating agency Standard & Poor's has upgraded the long-term corporate credit rating for Reliance Industry to 'BBB (plus)' from 'BBB'. However, the outlook will be negative in line with the sovereign rating outlook.
"We upgraded Reliance because we believe the company's strategy to grow organically will strengthen its competitive position and support its profitability," the agency's credit analyst Andrew Wong said. Reliance's articulation of its growth strategy removes the uncertainty regarding the company's use of its high cash balance, he added.
The agency said now it has greater clarity on the company's expansion strategy. The company intends to spend more than $30 billion on growth over the next three years, of which at least 75 per cent will be towards its core businesses of refining, petrochemical, and exploration and production (E&P). The agency also expects Reliance's planned projects to strengthen the company's competitive position in the refining and petrochemical sector.
It also said Reliance's pet coke gasification project should improve the company's refining margins, while petrochemical projects should bring in the benefits of higher value addition and vertical integration. The company's capital spending in E&P will enable it to grow its shale gas business and reverse the fall in production in the KG D6 gas field. "The planned capital spending is also likely to result in a better operating performance for Reliance over the next three to four years," Wong said.
The rating on Reliance continues to reflect the company's large-scale, integrated, and efficient oil refining and petrochemicals businesses, and good business diversity. These factors underpin the company's strong and recurrent, although somewhat cyclical, cash flows. The rating also factors in Reliance's exposure to cyclical industries and commodity prices and the concentration of the company's assets in India.
However, the agency said the negative outlook on Reliance reflects the outlook on the sovereign credit rating on India. "We could lower the rating on Reliance if we lower our transfer and convertibility assessment on India, which could happen if we downgrade the sovereign. We could also lower the rating if we expect the company's debt-to-EBITDA (Earning before Interest, Tax, Depreciation and Amortisation) ratio to remain above 2.5 times on a sustained basis," the agency added.
This could happen if the company's capital expenditure is higher than expected, significant delays or challenges in project commissioning adversely affects projection of an increase in the company's cash flows or a significant weakening of the industry undermines Reliance's operating performance.
"We could revise the outlook to stable if the outlook on the sovereign credit rating is revised to stable," the agency said.
← Youth held for sexually assaulting…
Man killed in full public… →


text:
A shortened version of the chapter by Richard Hewer and Alen McFadzean in Lakeland's Mining Heritage
The iron industry has slowly matured within the Lake Counties for centuries, with industrial growth spreading from the small bloomery and forge sites, coastal plateau workings and the narrow veins of the fells to the huge mining and iron smelting complexes of the late 19th and 20th centuries. The industry declined duriing the mid 20th century because of dwindling ore reserves, cheap foreign imports and the pressures of economic viability.
The mining areas were divided into well-defined regions. Major deposits occurred around Egremont, Cleator, Cleator Moor, Ennerdale, Eskdale, Millom and Ulverston, with numerous smaller deposits within the Lakeland fells – Langdale, Coniston and Grasmere for example.
Western Lakeland
The Whitehaven region has evolved from several distinct groups of rock. The carboniferous limestone overlying the Skiddaw slate on the south eastern side has in turn been overlaid by the coal meausures in the north-west. The southern area is covered by the St Bees sandstone. The principal ore bodies occurred within the seven bands of the carboniferous limestone series, the latter having been subjected to varying degrees of earth movement and faulting, whilst the iron solutions penetrated the fault lines from above and below. The resultant ore bodies formed large flats (bodies of solid ore) which connected with the bedding planes of the host rock, irregular bodies occurring as large swellings within the vein, or true veins or faults whereby the haematite solution followed the lines of weakness. the miners were forever optimists for, just ahead of them, the vein could open out into a new and profitable shoot of ore.
Large, shallow deposits were extensively worked by the early miners. Development was rapid – easily worked deposits provided greater profits – but with this ambitious drive came the dangers and disasters. Roof falls were commonplace, holing into abandoned workings and slides of disturbed ground were all part of the miner's way of life. In several instances, where all the ore had been removed from the slats, it was necessary to fill the large voids with waste rock, and in some cases sand was blown into the cavities leaving only heavily timbered shafts for access to the lower workings.
Several varieties of iron were mined. The most common type was compact, hard and massive, and of a bluish-purple hue (hard blue) usually associated with the flats. Kidney or pencil ore was often found in irregular deposits in the first or second limestones. Specular ore was something of a rarity often found in cavities (loughs) and saved to be sold as specimens by the miners (a lucrative sideline). Lesser ores consisted of dark 'black' soft ore; smite ore (very greasy and highly coloured; muck or 'ring' ore.
Research and fieldwork has shown that the deposits were exploited in Roman times. Several bloomery sites suggest operations by early British or Norse settlers. Many of the sites date from the late medieval period but could have obliterated earlier workings. The earliest documented evidence of mining within Egremont parish related to Bigrigg Mine in 1179. The surface cover was shallow and the deposits easily exploited, probably as open casts. Between 1179 and 1635 the search for further deposits was intensified. During the later years a large pure deposit of ore was discovered at Langhorn which, by 1709, when it was still being worked, had yielded over 21,500 tons of ore.
In 1784 Crowgarth Mine tapped a particularly rich body of hard blue ore. 20,000 tons were transported to the Carron Foundry in Stirlingshire. After this date there followed a 10 year slump in the iron trade which slowed development work in Cumbria. However, following this unsettled period the metal prices improved and mining gained momentum until the decline in the 20th century. Advertisements often appeared in the local papers offering plots of land "with great prospects of iron ore".
Exploration within the Lakeland fells was spasmodic. The veins of haematite were small, rich, but often mixed with stone. Tranpsport was difficult and iron prices were low. During the 1840s prospectors tried any likely veins, but it wasn't until the mid 1860s and early 1870s that serious attempts to work the lodes were instigated. The valley sides of Ennerdale Water received considerable attention, especially at the sites of ancient workings. The Crag Fell Mine was the only producer of any quantity. Meanwhile Floutern Tarn (Red Gill Mine) received notoriety for the activities in share dealing by Faithful Cookson who was also associated with several other ventures in the area and in neighbouring Eskdale. The trials around Scale beck and along the flank of Gale Fell provided a limited amount of ore which was sorted, cleaned, bagged and wheelbarrowed away!
The Kelton and Knockmurton mines were the only large producers of ore from the Skiddaw slate formation. The mines were owned by William Baird & Co of Gartsherrie, Scotland, who had ventured south in search of quality ore for their blast furnaces. Between 1869 and 1913 over 1.25 million tons were raised, much of which was transported to their works though some went to the Moss Bay and Harrington furnaces near Whitehaven and a little to the Midlands.
The mines of Eskdale have fortunately left us with the Ravenglass and Eskdale Railway. This was consrtucted solely to serve the mines, and was nearly 'lost' when the workings closed down. Nab Gill Mine, further developed in 1870 by Whitehaven Iron Mines Ltd, worked the veins in the Eskdale granite. It produced roughly 8000 tons per annum, but tonnage declined after 1881. The iron ore was extracted by overhead stoping and removed from Nab Gill by way of an inclined tramway to the main line.Gill Force and Gate Crag mines on the south side of the valley were the second major producer, served by a branch line from the Railway. Several small workings dot the valley slopes.
Southern Lakeland
The haematite ore fields of Furness are bordered to the north by Silurian slate and to the south by permo-triassic sandstone, the host rocks being a succession of six distinct limestones deposited during the Carboniferous period. Unlike the non-ferrous mineral veins of the nearby Lakeland mountains, the haematite lodes of Furness conform to no particular pattern. Only in certain circumstances – mainly in the southern and eastern areas of the ore field – do they manifest in true mineral vein form, the deposits of the north and west being in highly irregular masses.
Large-scale mining has taken place at a number of locations between the towns of Barrow and Ulverston. The major ore deposits were situated at Askam, Roanhead, Park, Yarlside, Stank, Mouzell, Crossgates, Marton and Lindal; with peripheral deposits at Urswick, Stainton, Pennington and Plumpton. Across the Duddon Estuary, in the carboniferous limestone between Millom and Haverigg, ore was mined at Hodbarrow from one of the largest bodies of haematite ever discovered. Three miles to the north-west an outlying vein in the Wicham Valley yielded haematite ore from the fault between the limestone and the older Skiddaw slate.
Just when mining began is a point open to conjecture. Archaeological evidence determines that ore was smelted in the vicinity of Urswick during the Iron Age by indigenous Celts. Cistercian monks from Furness Abbey commenced mining at Orgrave, on the outskirts of Dalton, prior to 1235, and by 1300 had developed several locations for the winning of ore, mostly in the vicinity of Dalton. These initial ventures were probably open cast workings, exploiting shallow layers of mineral worked with ease once the overlying boulder clay had been removed.
Mining methods varied considerably across the Furness and Hodbarrow ore fields. In the narrow mineral veins around Urswick and Stainton, traditional methods of stoping were employed. In the veins, cross veins and ore flats of Whitriggs – where the ore tended to mass in irregular pockets between the limestone bedding and natural rock fissures – the ore was systematically robbed, allowing the roof to collapse and reveal more ore. In the gigantic ore bodies (sops) of Park, Roanhead, Mouzell, Elliscales and Lindal Moor top slicing became widely adopted. This was a method similar to the board and pillar system of mining coal, the difference being that the pillars were also removed, allowing the roof to crush down on the sole while another slice was being worked underneath.
The Hodbarrow deposit was, like the sops of Furness, large and irregular. Top slicing was employed prior to 1922, but problems with subsidence and the close proximity of the sea brought about a change in policy and the adoption of bottom slicing. Ore was removed in slices from the sole of the deposit and the resultant voids filled with a slurry mixture of water and sand to prevent instability.
Water was a problem in the Furness mines. With the country rock being carboniferous limestone underground runners and feeders were plentiful. Cornish beam engines were installed here and across the Duddon. Horizontal pumping engines were common throughout the district, while during the early years of the 20th century several companies resorted to electrification as a means of improving their de-watering systems.
After the peak years of the 1870s and 1880s, decline was hastened by the gradual exhaustion of some of the older pits and the import of cheap iron ore from other countries, notably Spain. In Furness the last big pit – Woodbine Pit at North Stank – closed in 1946. The end came in 1960 when the Margaret Mine and inclined drift in Henning Valley, Lindal, was bought out by a large concern and subsequently closed. Hodbarrow Mine continued in production until March 1968 when its greatly reduced work force of 103 men was laid off, bringing to an end haematite mining in the south of the county.
Furness iron : Mark Bowden (ed.), English Heritage, 2000
The red earth (The iron mines of Furness) : Dave Kelly, The Author, 1998
The red hills (West Cumberland) : Dave Kelly, Red Earth, 1994
The iron moor : Alan McFadzean, Red Earth, 1989
Cumberland iron (The story of Hodbarrow Mine) : Alan Harris, Bradford Barton, 1970
Master of them all (Iron making in Cumbria) : Various, CIHS/HMS, 2007 (see publications)
The metalliferous mines of Cartmel and South Lonsdale : Max Moseley, Northern Mines Research Society, 2010
The story of iron ore mining in West Cumbria : Mervyn Dodd, The Cumberland Geological Society, 2010
FEATURED SITE
The Mines of Eskdale (article)
Iron ore mining around Lindal-in-Furness (web site)
Cumbria sites listed in the MMP Step Three Report for iron and steel industries:
** sites are of "clear national importance", * sites are "of national importance"
Grid Ref
Florence Mine NY017102 **
Nab Gill Mine, Boot NY173013 **
Hodbarrow Mine NY175785 O (i.e.destroyed)
Violet Pit, Roanhead Mine SD207749 **
Roanhead Magazine SD20927536 *
Askam S5 Pit spoil heaps SD209766 **
Elliscales No4 Pit engine house SD22587482 *
Stank Pit pump house and mine SD232707 **
Colorado Pit windmill SD235754 *
Woodbine Pit SD236723 *
Poaka Openworks SD244772 **
Henning Wood Mine SD246764 *
Daylight Hole and Diamond Pit SD253764 **
Lowfields and Parkside Mines SD259760 *
Urswick Fell Opencast SD260740 **
N.B. Peter Sandbach writes (12 September 2006):
I may be responsible for the suggestion that a magazine exists at Roanhead. If so, I was wrong. It is actually an engine bed for No 16 Pit, but fitted with an arched roof about 1945 to serve as an air raid shelter (See CATMHS Newsletter 58). Two of the sites mentioned no longer exist. Elliscales No 4 engine house was demolished last year and the remains of a windmill near Colorado Pit have gone.