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UCF Muslim students aim to create prayer room for all
The MSA is attempting to work with the SGA to establish a prayer room for members of all religions.
UCF Muslim students aim to create prayer room for all The MSA is attempting to work with the SGA to establish a prayer room for members of all religions. Check out this story on centralfloridafuture.com: http://www.centralfloridafuture.com/story/news/2015/10/07/ucf-muslim-religion-students-sga-create-prayer-room-union/73529332/
Nicole Garcia, Central Florida Future Published 2:57 p.m. ET Oct. 7, 2015
Students use a prayer room for one of the five daily prayers required in the Islam religion.(Photo: Nicole Garcia, Central Florida Future)
One room filled with prayers from people of various religions.
That's what the Muslim Student Association is attempting to work out with the Student Government Association. The organization, which is tasked with reserving a new room in the Student Union for prayer every day, is aiming to establish a prayer room for members of all religions.
Establishing a permanent prayer room would eliminate a major obstacle for the organization.
Muslims pray five times per day according to the position of the sun, and daily prayer is an essential aspect of Islam. The MSA aims to provide a safe space for its members to pray, but the constantly changing room assignments can be challenging.
Muslim UCF students combat hate with peace
Although the organization has recently adopted a system of text messages notifying members of room locations for the week, gathering members for prayer is still a challenge.
"Since we pray five times a day every day, we need a prayer room every day," said Noor Qadri, secretary of the MSA and a junior interdisciplinary studies major. "The registrar's office takes a while to get back to us regarding room reservations, so I have to reserve the room, and on top of that, I have to tell everyone what room we'll be praying in."
Reserving a room for Friday, Islam's holy day, is a particular challenge for the organization. Most of the time, the room the MSA is given isn't large enough to accommodate the influx of students who come to attend Friday's sermon.
"We usually have upwards of 70 people come and pray," said Mohamed Mohamed, president of the MSA and a senior biomedical sciences major. "A lot of times, the room gets really tight."
Former Student Body President Melissa Westbrook's SGA administration attempted to create a prayer room two years ago, but the project fell through due to space conflicts.
There's no room for retaliation in Islam
"The prayer room was supposed to be a room on the second floor of the Student Union, but the LEAD Scholars office occupied the space at the time," said Westbrook, who is pursuing a master's degree in nonprofit management and public administration. "I do think it's still an option on the table at this point."
The prayer room would be modeled after Orlando International Airport's "Reflection Room" and the University of South Florida's "Serenity Room."
For Maha Qureshi, the public relations director of the MSA and a senior communication sciences and disorders major, a prayer room is more than a space for fulfilling her duties as a Muslim.
"It helps us stay connected to our faith and reminds us that we're not alone," Qureshi said.
Nicole Garcia is a Contributing Writer for the Central Florida Future.
Read or Share this story: http://www.centralfloridafuture.com/story/news/2015/10/07/ucf-muslim-religion-students-sga-create-prayer-room-union/73529332/


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Blood on the Motorway
Sleepwalk City
A Final Storm
Welcome to Discovery Park
PAUL STEPHENSON BOOKS
Horror - Sci-Fi - Music
Under the Influence - The DNA of The Sunset Chronicles
July 8, 2019 Paul Stephenson
Photo by Hal Gatewood on Unsplash
My new book, Sunrise, the first book in my epic Dystopian Sci-Fi series will be out in less than two months. That's pretty exciting, and a little bit terrifying, if I'm going to be honest. But as I ramp up, one thing my readers have been asking me is... what's it like?
In Writing Chronicles, Writing, TV, Self Publishing, Music, Movies, General, Books Tags Writing, amwriting, influences, the wheel of time, elder, Aliens, nuke the site from orbit it's the only way to be sure
Win a truckload of Walking Dead goodies.
May 3, 2018 Paul Stephenson
I've spoken before about the role that the comic of The Walking Dead played in me becoming an author. Before it became a sprawling and colossal TV series, I got quite addicted to the graphic novel. At that time I was already writing a tale about two layabout stoners going on a road trip in the UK, but it wasn't going anywhere. Then I got the first volume of The Walking Dead, where Kirkman spoke in his intro about getting to the end of every zombie film ever made and wondering what happened next. I felt the same way about every end-of-the-world tome I ever came across. My road trip novel soon morphed into the apocalyptic tome it is today. I wanted to explore that same idea, except removing the zombies altogether.
So, with the second anniversary of the release of Blood on the Motorway fast approaching, I'm beyond delighted to be involved in a very special Walking Dead themed giveaway. Unfortunately, it's only open to you if you're in the US, so if that's not you then, well, sorry about that.
If you are in the US, here's what's up for grabs:
'Rick' Walking Dead Fleece Blanket
8" Michonne Walking Dead Vinyl Idolz figure
Daryl Crossbow Coffee Mug
Daryl Crossbow & Angel Wings Walking Dead Keychain
Walking Dead pen & bookmark
Walking Dead luggage tag
Walking Dead magnets
Walking Dead Comic #1
Walking Dead Mini Calendar
Walking Dead button badges
Zombie-opoly Board Game
Zombie 'Where's Waldo' book
Zombie Colouring book for grown-ups
The Ladybird book of the Zombie Apocalypse (for grown-ups)
Zombie necklace
Zombie Outbreak car decal
28 Days Later/28 Weeks Later Blu-ray Set
Romero Dawn of the Dead/Land of the Dead Blu-ray Set
'Undad', Author Shane W. Smith
'A Place Called Hope' & 'A Place Outside the Wild', by Daniel Humphreys, signed by the author.
Entering to win is easy. Just enter your name and email at this link. Follow sponsoring authors on other social media platforms and share the giveaway for additional entries. By entering this giveaway, you AGREE TO BE SUBSCRIBED to the sponsoring author's newsletters listed in italics below. You may individually unsubscribe at any time.
Sponsoring Authors: Eli Constant, Claire C. Riley, Russell Nohelty, Dani Dixon, Matthew Jones, Daniel Humphreys, E.B. Black, Shane W Smith, Kristen Renee Gorlitz, Erica Gerald Mason, L.K. Hatchett, Baileigh Higgins, J.D. Oliva, Carmelo Chimera, N.S. Paul, Tyler James, David Lucarelli, Terrance Grace, & Pauline Creeden. Oh, and me.
Best of luck to you, I'm extremely peeved that I don't get to enter it myself!
In General, Movies, TV Tags Walking Dead, Giveaway, Inspiration, Freebies, Competition
A monkey holding a watermelon
February 15, 2018 Paul Stephenson
I've had a blog for a very long time. Over 15 years. Recently I've been thinking how it'd be nice to bring back some of the better old posts, once a week. I'm starting with a series that I did back in 2009, before Blood on the Motorway was but a twinkle in my eye. I'd asked for seven one blog topics from people on Twitter and got some of my best blog material as a result. Here's the fourth, a suggestion from, well, I'm not sure who suggested it. Lost to the sands of time. Originally posted on August 28th, 2009, a time when my now-ten-year-old daughter was only two years old.
From the vaults: 7 Days, Day Four.
One of the bewildering things about becoming a parent is the lack of basic instructions. If you go to Argos and buy a piece of furniture you will find assembly instructions enclosed within, and yet when it comes to being given a newborn child, which will require much more effort and constant management than a three-tier wardrobe will ever do, you get nothing. At the very least they should provide you with the child equivalent of an Allen key, a multi-purpose tool that can stop it from crying or deal with the never-ending flow of poop.
One of the things they should prepare you for is how much children's television has changed since you last bothered to tune in. The main example of this is the advent of all-day children's channels, such as the wonderful and yet bewildering Cbeebies. No longer are children's programmes a way to settle a child for a few hours in the afternoon, now they provide it from the moment your child wakes you up until the time they go to bed, like a constant opium release for your child.
Of course, this leads to the temptation, especially on those weekend days when you are feeling a little worse for wear, to just pop it on and leave it running all day, like a constantly running distraction machine. But (and this is where the warning comes in) you do this at your peril because soon you will get sucked into the bewildering world within. When I was a child I doubt that my parents could name any of the characters of the programmes I watched. They lacked any awareness of the organisational structure of the Autobots, for instance. And yet I can name virtually every character that comes on Cbeebies over the course of a day. I know the words to all the songs they sing on Me Too, have seen every episode of In the Night Garden and have even found myself leaving the channel on when Rosie isn't even in the house, dancing around to Boogie Beebies.
But none of this prepared me for the latest marvel to grace Cbeebies. The terror that is Waybuloo. I first stumbled across this one afternoon after Rosie and I had been to the park. After two hours of running after a toddler as she attempted every single area of the park that she was not old enough to go on, we returned home with me far more exhausted than her. I popped on Cbeebies and curled up on the sofa to die.
About half an hour later I woke, with a strangely serene feeling washing over me, as the gentle music of pan pipes and clinking crystals greeted me. I opened my eyes and could see Rosie transfixed to the screen. I glanced at the television, trying to make out what was going on.
It was no good. On the screen were what appeared to be three small monkey-like creatures, all laying on the floor doing yoga. Then they suddenly exclaimed something in a weird language and started to float off the ground, manic smiles plastered on their faces, eyes huge with dilated pupils. The screen cut to another of the little monkey creatures, this time holding what appeared to be a watermelon. Another was jumping calmly up and down on a box, neither of them showing any expression other than what appeared to be a manic bliss. The monkey holding a watermelon handed it to another monkey and then flew away without a word. 'Noktok,' said the other monkey creature, and walked away to do some more yoga. Everything was so surreal that I wouldn't have been in the least bit surprised if what they'd actually said was 'Nobody puts Noktok in a corner.'
I watched the rest of the episode without a clue what was going on, but unable to look away. Even the most surreal episode of In The Night Garden will still furnish the viewer with some plot, generally about someone losing something and then finding it again, but try as hard as I could, there was no plot to be found here.
Afterwards, I turned the television off, despite the protestations of Rosie, who began immediately to shout 'Beebies.' I looked at her, and said 'We're going to go back outside Rosie, I think we need to make sure that the world is still real after that.' She nodded and headed for the door. Thankfully all was as it had been only an hour before. But for a while there I was beginning to suspect some kind of cosmic shift, the world spun out of orbit by the sheer oddness of the show we had seen.
Needless to say, it's now Rosie's favourite show.
Blood on the Motorway: An apocalyptic trilogy of murder and stale sandwiches is out now in ebook and print from Amazon and all other good bookstores.
In From the Vaults, General, TV Tags 7 Days, Waybulloo, Cbeebies, Stories
January 12, 2017 Paul Stephenson
In this time of #goldenshowers, blank dossiers, Home Secretaries preaching hate to their own conference, incoming Trumpageddon, and U2 touring again, I don't really want to be the one to add further ill tidings. Really I don't. So it is with a heavy heart and a sombre voice that I have some terrible news to impart.
My subscription to Sky Movies has less than thirty days left to run.
I'll just stand back and let that sink in.
I know, devastating, isn't it? As much as I'd like to be able to claim this is all because of us tearing up our contract with the Murdockian devil in an act of political defiance, I can't. It's just that our six month half price offer has finally expired. I know, I'm hanging my head in shame for giving him six months of my money, even at half price.
The worst thing is, that once it has gone, it'll take all of the movies I recorded to my TiVo box with in, in an act of pettiness equivalent to that being displayed by the President Elect. This means that from now until the 9th of February, I have to do some hardcore film-watching. No, wait, not like that.
Here's all the films I currently have recorded:
Tomorrowland: A World Beyond
The Second Best Exotic Marigold Hotel
Time Out of Mind
Now, bearing in mind that my good lady wife wants to see all these films too, that we have two young children, we both work a hell of a lot, and that I'm spending five days in a completely different country, the chances are we're not going to get to all these. So, in order to help us select which ones we're going to prioritise, I need your help. That's right, imagine there's a mocked up American Army recruitment poster here of some kind. I need you to let me know which ones you'd see first, so that we can use those comments in pitched battle when we can't agree which film is worthier of watching than the others.
Done? Okay, you can go back to reading about Trump again. Cheers.
No, wait! I almost forgot. Sleepwalk City comes out tomorrow! So, why not sun out now and bag yourself the pre-order, and help it rocket with up the charts upon release? Seriously, it'd really help. For more details, head here, and click on one of the boxes.
Blood on the Motorway – An apocalyptic tale of murder and stale sandwiches, is available on Amazon, iBooks, Kobo and more besides.
If you want to know more about me or my books, you can follow me on Twitter, like the Facebook page, or follow me on Instagram. For news, offers, and special content, sign up for the mailing list.
Welcome to Discovery Park – the chronicle of my increasingly frustrated attempt to listen to every album on Rolling Stone's Top 500 Albums of all-time list, is available now on Amazon Uk, Amazon.com, iBooks, Kobo, and many more.
In Begging, Movies, TV Tags film, silly
Steal your idols
July 17, 2015 Paul Stephenson
This week I was listening to one of the eleventy billion writing podcasts that I subscribe to in the vain hope that they'll somehow magic me into becoming a better writer, and they were discussing taking inspiration from existing works. Before you cry plagiarism, we're talking...
In Writing, TV, Movies, Books Tags writing, vampires
Utopia Gone
October 14, 2014 paulformulaic
I was gutted to hear over the weekend that Channel 4 have decided not to re-commission Utopia, the mind-bendingly excellent sci-fi conspiracy thriller. From what I can tell the ratings just didn't justify the expense, which is a damn shame.
If you missed it, Utopia was a blend of high art and low culture that merged comic books, international conspiracy, grimy horror and comedy along with an unbelievably vivid visual aesthetic that was utterly captivating. It was bold, scary, funny and bonkers, with great character, dialogue and plot. It was, in short, one of the best examples of genre TV to come out of this decade.
Which explains why the concept has been picked up by no less a director than David Fincher, who will apparently be remaking the series for American telly and helming the lot himself. That the cancellation announcement comes hot on the heels of that announcement is a double blow, though. I'm a huge Fincher fan and I'm sure he'll do a good job, but the original is so quintessentially British and bonkers that I can't imagine it'll be as good as the original.
When the remake was announced with some fanfare, I had thought that it might be good news for the UK version; that the publicity and kudos that came with Fincher's name (especially with Gone Girl riding so high in the charts) might be enough to overcome the poor figures for season two and get a third series commissioned, but that appears not to be the case
One of the things that was so good about Utopia was that alongside a very distinct look and feel, it took a pretty interesting stance on its cast, with an excellent gender balance and a good ethnic mix that made it much more believable, grounding it in a reality that really allowed the more surreal elements of the plot to go where they needed to without untethering it from reality.
I was watching the first series while I was writing the second draft of the book and it really hit home to me just how lazy it is to populate your story with a predominantly white male cast. Quite aside from the fact that representation matters, it really closes off some interesting areas your story can go. Utopia had some very traditionally male archetypes played by women and made much more interesting as a result, and vice versa. It had POC main characters whose race didn't define their characters absolutely, but who were very real. Throughout its cast it played with convention, made layered and interesting characters and became so much more engrossing as a result.
By adhering to a more realistic view of the world Utopia became more than just another genre offering, and it's this approach that has me completely reassessing the characters in my own story to see how much of this approach I can bring to my own work.
So goodbye Utopia, you mad bastard of a show. Cheers for the inspiration.
In TV, Writing Tags cancellation, gender balance, TV, Utopia
Blood on the Motorway: The Complete Trilogy: An apocalyptic trilogy of murder and stale sandwiches
By Paul Stephenson
Blood on the Motorway, Self Publishing, Reading
A treasure trove of post-apocalyptic freebies
Writing Chronicles, Writing, TV, Self Publishing, Music, Movies, General, Books
Interview, Reading, Self Publishing, Writing Chronicles, Writing
Interview: Post Apocalyptic author M.P. Fitzgerald
Blood on the Motorway, Books, Net joy
Last call for five star sci-fi
Books, Blood on the Motorway, Self Publishing, Writing Chronicles
Get your hands on some incredible five star sci-fi
Genre Change
Blood on the Motorway, Self Publishing, Writing Chronicles, Writing
My research process, AKA trying not to drown in procrastination and recrimination
tinkity tonk old fruit, and down with the nazis

redpajama_set_name: RedPajamaCommonCrawl


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Lawfare, Democracy and Human Rights in Latin America
Martonio Mont'Alverne Barreto Lima, Ana Maria D'Ávila Lopes
EMAIL THE ORGANIZERS
The proposal of this research aims the study of cases in Latin America and the eventual compromise of the democratic quality of the constitutions of these countries, the strengthening of institutions that apply the Law – the Judiciary, the Public Ministry and the Bar of Lawyers – and the preservation of Human Rights. The social perception of the instrumentalization of the Judiciary has triggered enormous damage to the valuation of democracy and human rights among the societies of America Latina, which becomes more acute with the political instability that such crises have caused. International courts, such as the Inter-American Court of Human Rights, and also organizations as the United Nations, were called to act in these processes and their participation, at least in the Brazilian case, which took place through the United Nations Human Rights Committee, in Geneva, Switzerland, in August 2018, during the Brazilian presidential elections. The participation of international institutions of mediation in internal affairs shows that the constitutional pact of any society can evidence the internal institutional disagreements, requiring international attention from the organizations that include the analyzed countries.
LSA Facebook
LSA Twitter
Donate to LSA


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Q: Assign to .GlobalEnv with assign I have a function:
myfunctionIs=myfunct(x,y){
#Some calculations and assign my lists to globalenv
theList1<<-theList1
theList2<<-theList2

#Nested function
function(...){
theList1=get("theList1")
theList2=get("theList2")

##Some calculations...
#NamesList calculation
 NamesList= ###Some Calculations

ListContainer=c(deparse(substitute(theList1)),deparse(substitute(theList2)))

for (i in seq_along(ListContainer)){
        assign(ListContainer[i],mapply(function(x,y) {

          ##Some calculations

          return(x)

        },x=get(ListContainer[i],envir=parent.env(environment())),y=NamesList,SIMPLIFY = FALSE),
        envir=.GlobalEnv)
      }

}}

I am trying to assign theList1 and theList2 back to .GlobalEnv but I get the error
Error in get(ListContainer[i], envir = parent.env(environment())) :
  object 'structure(list("2002-12-31" = structure(list(Date = c("2000-01-31", ' not found

I believe that the error comes from
get(ListContainer[i],envir=parent.env(environment()))

Because the calculations work correctly if I work in GlobalEnvironment.
Any ideas?
Best Regards
EDIT
That works:
Change ListContainer to:
ListContainer=c("theList1","theList2")

Was some issue with deparse(substitute... inside the function.

A: That works: Change ListContainer to:
ListContainer=c("theList1","theList2")

Was some issue with deparse(substitute(..)) part.
Or maybe that could work too with some adjustments:
ListContainer=c(quote(theList1),quote(theList2))

and then
eval(ListContainer[i])

in the loop.

redpajama_set_name: RedPajamaStackExchange


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Alejandro Rosario Wiki, Biography, Age, Height, net Worth, Girlfriend
Celebrity Net Worth On February 2, 2021 By Jeevan Shetty
Alejandro Rosario was born on January 14, 2003, and from New Jersey, USA, he is a Social media personality, TikTok Star, and Instagram Influencer, now he's in the media headlines after Nikita Dragun dubbed 'predator' after flirting with 18-year-old TikTok star Alejandro.
Nikita is a YouTuber, make-up artist, and model, recently she came under fire on the social media platform after many users noticed that Nikita commented on the Alejandro Rosario picture "u 18 now right? …asking for a friend," he then replied "mhm."
Later, Nikita uploaded a picture of her with Alejandro Rosario on IG stories to which one user Tweeted "She's fast." Nikita was born on 31 January 1996 and she is 25 years old as of 2021, Youtuber Nikita's comment on Rosario's photo led to people calling her predatory.
Who is Alejandro Rosario?
He is an Instagram Star and TikToker who boasts 5.5 Million followers, he mainly uploads video such as comedy skits, vlogs, transition videos, and many more.
Alejandro's first TikTok video uploaded with his dog, on Instagram he has 1.5 Million followers. Alejandro turned 18 years old on January 14th, 2021, he also has a Youtube channel under his name.
Furthermore, he earns money through product advertisements and from Instagram, also he sells his own merchandise through a third-party website.
In his free time, he likes to play soccer and spend time with his dogs. Besides this, he started his own TikTok group called "The Lollipop Boys" and the other members are Mattia Polibio, Mattia Polibio, Alvaro Romeo, and Kairi Consentino.
How old is Alejandro Rosario? He was born on January 14, 2003, and from New Jersey, USA, he is 18 years old as of 2021.
He was born to Adriana Villalta (Mother), Emilio Cascante (Father), and has a younger brother named Emiliano.
On January 23rd, he shared his dad's picture on Instagram and wrote "happy birthday pops love you so much and so grateful to have you in my life!!."
Previously, Alejandro Rosario shared his family picture and wrote "where to start, I just wanted to say how grateful I am for all of you and the countess support you have given me it's something I will cherish for the rest of my life. my family who has been there for me through everything and love me no matter what I do, and lastly my friends who have been here since the start of everything you guys are my brothers for the rest of my life no matter what happens and to the new friends I've made through tiktok thank you for being such great friends to me. I love you all happy thanksgiving <3."
His Net Worth is $750K USD as of 2021. He stands 5 feet 9 inches tall and weighs around 74KG.
Asian Andy Wiki, Biography, Age, Height, Net Worth, Girlfriend
Hoodrich Pablo Juan Wiki, Age, Height, GIrlfriend, Family, Biography
On January 18, 2019 By Jeevan Shetty


Tourism is Nassau County's largest job creator and a leading driver of its economy. Our vision is to position Amelia Island as one of North America's top 10 island destinations, maximizing the return on tax dollars invested, increasing demand, and enhancing the visitor experience. Our programs are funded by a 5% tourist tax on short-term accommodations. We dedicate over 75% of that revenue to advertising and promoting Amelia Island using a variety of channels.
Visit AmeliaIsland.com to see more and follow us on Facebook and Instagram.
Developing a sustainable tourism program is an essential part of ensuring an economically robust Nassau County. The hospitality industry supports over 25% of jobs, generates 38% of sales taxes, and over $40 million in net economic benefits to Nassau County. Ensuring that the tourism industry improves the quality of life for residents is essential to maintaining the quality tours and product.
The investment made by the Board of County Commissioners allows us to be competitive in the marketplace - targeting customers who stay longer and spend more, thus achieving our goals as stewards of the destination.
Amelia Island TDC is committed to ensuring digital accessibility to the widest possible audience, regardless of technology or ability. As part of these efforts, we are actively working to improve the user experience for everyone, and in doing so, adhere to pertinent accessibility standards and guidelines.
We welcome your feedback on the accessibility and functionality of our website. If you would like to report any accessibility suggestions or problems, or if you would like to request accessibility-related assistance, please contact us at info@ameliaisland.com or at (904) 277-4369.


DDS - Sysops' Pets - Reptiles!
These pets are owned by Bryan Turner of Vagabond Software and Pegasus Flight BBS. Bryan has contributed much to the BBS world in the form of mainly freeware BBS doorgames and utilites and always has innovative ideas for new software. See photos of his other pets on the various pages here.
Snake - Western Hog Nose about 12 Inches long. Its name (via Brianna) is "Snakie"
Iguana - (again named by Brianna) "Lizzie"
With tail it is about 2.5 Feet. It is a 6 month old Green Iguana. When it is full grown it will be about 6 ft long. When Bryan first got it it was in a 10 Gal tank which it took about 3 weeks to out grow. The picture of Bryan's daughter, Brianna, standing next to the cage is the cage that he built and will need to expand on when she gets a little bigger.


The U.S. Food and Drug Administration today took a significant step forward in driving the efficient development of novel diagnostic technologies that scan a person's DNA to diagnose genetic diseases and guide medical treatments. For the first time, the agency has formally recognized a public database that contains information about genes, genetic variants and their relationship to disease. The FDA is recognizing the genetic variant information in the Clinical Genome Resource (ClinGen) consortium's ClinGen Expert Curated Human Genetic Data, which is funded by the National Institutes of Health (NIH), as a source of valid scientific evidence that can be used to support clinical validity in premarket submissions. The information contained in this open database has been collected and studied by researchers across the world. This recognition by the FDA will facilitate test developers, including those that use a technology known as next generation sequencing, to rely on the information available in the database to support the validity of their tests, instead of having to generate the information on their own.
Genetic tests work by looking at a person's DNA to detect genomic variations that may determine whether a person has or is at risk of developing a genetic disease and, in certain cases, may help to inform treatment decisions. Unlike traditional diagnostics that typically detect chemical changes associated with a single disease or condition, DNA-based assays can look at hundreds to millions of DNA changes in a single test to help determine the cause of a person's disease or condition.
Most genetic data are not aggregated and stored in a manner that is accessible to many researchers and clinicians. Recognizing the benefits of public databases, the FDA issued a final guidance in April 2018 to help accelerate the development of reliable and beneficial genetic tests. The agency's policies seek to encourage data sharing and outline an approach clarifying how test developers may rely on clinical evidence provided in FDA-recognized public databases to support clinical claims for their tests and help provide assurance that the test is "clinically valid," which, in the case of genetic tests, is the relationship between a gene variation and a specific disease.
Today's action – which recognizes the ClinGen consortium's ClinGen Expert Curated Human Genetic Data as a source of valid scientific evidence that can support clinical validity – means that developers of genetic tests have assurance of the reliability of the freely available data that they can use in support of their applications for marketing authorizations with the agency, rather than generating the same data on their own. The new recognition means developers will not need to demonstrate to the FDA the reliability of the database, the data and information within which can be used to support the relationship between a gene variation and a specific disease that are within the scope of the recognition. For example, the sponsor of a test that detects variants involved in hereditary cardiomyopathy could point to the cardiomyopathy genetic variant information available in ClinGen as part of a submission to support clinical validity of their test.
The FDA recognized the database using the process detailed in the April 2018 final guidance. The agency reviewed ClinGen's standard operating procedures and policies, including processes and validation studies for variant evaluation, data integrity and security, and transparency of all evidence. The FDA also reviewed the policies for how the consortia qualifies and approves researchers and clinicians to evaluate variants, including conflict of interest and disclosure policies.


text:
Pipeline industry organizes info campaign to prevent ruptures caused by vessels
Two organizations want to provide mariners with information to help them avoid vessel collisions with undersea pipelines.
Coastal and Marine Operators (CAMO) and GulfSafe intend to mitigate risk to mariners and infrastructure in the Gulf of Mexico. The groups, which were established by the pipeline industry, are using education and hazard notifications.
They are producing educational DVDs and plan in-person presentations to mariners' groups. CAMO has created a safety checklist for mariners to use in voyage planning near pipelines, and it provides advice on how to react if there is a rupture or grounding.
"The most important thing that a mariner can do (if there's a collision) with a pipeline, whether it is gas or oil, is to immediately note their GPS position so that they can report it to the National Response Center and have the line shut down," said Ed Landgraf, founder of CAMO.
Next the crew needs to determine if the leak is oil or natural gas, which is odorless and dangerous.
"If it is gas, they should ideally shut down the engines and electronics, cell phones and open flames until the pipeline is secured," Landgraf said. "If possible, they should not move — to prevent further damage or risk of explosion."
The checklist is available to download at www.camogroup.org. The list urges mariners to consider draft and tides and identify pipelines on voyage plans. The crew should use current charts. The website also contains mooring advice and vessel evacuation plans.
CAMO includes mariners and companies with pipelines, flow lines or other infrastructure on or below the Gulf sea floor. The group highlights coastal and marine pipeline threats, both natural and manmade, including drill rigs, jack-ups, work boats, spud barges and supply barges.
Beginning in April, CAMO plans to conduct awareness meetings for mariners, free of charge. The goal will be to help them recognize and identify leaks and to improve safety practices. The meetings will also solicit feedback from mariners on the best ways to handle unexpected encounters with a pipeline.
Landgraf said a key component of the program is GulfSafe, a free offshore damage and hazard notification system. GulfSafe operates like land-based phone centers that excavators call to find out if underground utility lines are present.
"A one-call notification system is essential in preventing third-party damage and unauthorized encroachments to coastal and marine pipelines," Landgraf said.
He noted several preventable incidents that occurred in the Gulf in recent years. One involved a spud barge that barely missed a 20-inch oil pipeline carrying 400,000 barrels a day. Surface markers were placed only after a helicopter discovered just how close the barge was to the pipeline.
Other incidents did not have such a happy ending. In May 1997, 5,000 barrels of crude oil were released into Terrebonne Bay when a spud barge struck a pipe. In a similar accident in West Cote Blanche Bay in 2006, six workers were killed.
Data compiled by CAMO from 1987 to 2007 revealed 118 pipeline strikes by either vessels or anchors, along with 25 fatalities and 17 injuries. The environmental impact from those spills was about 100,000 barrels.
Along with CAMO's training initiative, GulfSafe plans to spread the word about the hazards pipelines present to mariners. GulfSafe is producing a 15-minute informational DVD for distribution to industry stakeholders including mariners, port authorities and marine fueling stations. The video will explain how to use the "one-call" system before embarking on a voyage and how to report a leak.
The DVD will be distributed by direct mail to specific vessel operators such as dredge companies. It will be on display at trade shows and through industry associations such as the Offshore Marine Service Association. It will also be available online.
"GulfSafe will also be conducting training sessions for mariners later this year," said Jack Garrett, the company's director of regulatory services.
In conjunction with CAMO, GulfSafe plans to set up the mariner training in several areas in Louisiana this fall and winter, he said.
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I thought I should write an update on where I've gotten with RottenFlix since the last post.
In my last post, I mentioned some plans that I had for enhancements.
In the future, one major enhancement I'd like to make to RottenFlix is to redesign it to use Web Workers. My original design of RottenFlix fetched all relevant movie ratings up-front with no action required from the user, but it was just too slow and it blocked the UI awkwardly. With Web Workers I'm pretty confident I could go back to my original vision and make it fast and usable.
There's also the issue of new movie titles that are brought into the page via Netflix's own Ajax effects. RottenFlix does not currently handle those movie titles. I could probably make this work, but I'm not sure how.
Well, after banging my head against the wall extensively on both of these issues, I've reached some conclusions.
It's not actually possible to use workers within Greasemonkey. After much experimentation, googling, and finally Stack Overflowing, I had to accept the fact that my dream of a multi-threaded RottenFlix was dead. Bummer.
Anyway, good work! Wishing it automatically added the % but, its all better than having to switch tabs and search!
I, too, wish I could make RottenFlix load all the rating percentages automatically without user interaction, but it just ain't happenin'.


Just like spring, fall is ideal for planting. Why? Because the cooler temperatures, rainfall, and short, bright days will help plants make a fast and easy transition to your landscape. In fact, the entire first half of autumn gives them the opportunity to grow roots and settle into their dirt-y home. But before you get into your car and drive to the nearest garden or home improvement center, you should know what to plant in the fall to ensure you'll have a bountiful spring harvest. Keep reading to learn more.
Yikes! You only have a six-week window before your ground freezes. Once it does, root growth goes dormant until spring. Why six weeks? Because it allows plants time to get acclimated to withstand the cold and snow. However, when your ground actually freezes will vary from year-to-year. In fact, you may find that you don't have frozen ground at all. Just let it go and wait to plant until mid-November because it's a safe planting deadline for most areas. As long as your plants are in the ground before it freezes, you're good.
Speaking of freezing ground. Any plants you have in nursery pots should be in the ground before winter. Don't worry because it's good for them to be planted and protected in the ground rather than in plastic pots that can crack and split. You can always move your plants in the spring to a better location. Also, make sure you water them after planting and continue to do so until your ground freezes. Even though fall can be rainy, your plants may require additional water. They may also need a lot of mulch to keep them insulated. Not only will it protect your plants, but will provide them with a great environment to develop roots.
When it comes to fall planting, it's important to give your plants a chance to experience root growth, which goes on until temperatures average 48-degrees Fahrenheit. Come spring, you'll see and enjoy the fruits of your labor!
What to Plant in the Fall!
If you're a seasoned gardener, you may be worn out from gardening by the time fall rolls around. If you're a beginner, fall may be the best time for you start because of the cool weather. Whatever the case, it's easy to plant bulbs in the ground or pots or planters on your patio. And quite frankly, nothing soothes the soul like seeing snowdrops peeking through the snow. With all of this in mind, let's dig into what to plant in the fall!
Lett-uce (get it) talk about planting this tasty and leafy main attraction of a green salad. Keep in mind that butterhead and romaine tolerate the cold. Sow lettuce seeds in pots or garden beds eight weeks before your area's first fall frost. Stagger your sowings at least two weeks apart. When you reach the four-week mark before your area's first frost, sow your lettuce.
Like garlic? The best harvest is during fall planting. Plant your bulbs quickly, so the roots have time to grow. However, you don't want to plant them too early because they may sprout through the soil. Plant garlic about four to six weeks before your ground freezes. Once planted, add a heavy layer of straw because it will protect and insulate the soil, support worm activity, and further root growth.
Are you a fan of The Office? If you are, then you know that Dwight Schrute, the highest-ranking salesman, and assistant to the regional manager at the Scranton branch of the Dunder Mifflin Paper Company may have been onto something with his beet plantation. Beets are great to plant in the fall. The trick is to soak the seeds overnight for quicker germination.
There's a reason why Brussels sprouts are on menus and dining room tables during the holidays: they hold up in an early frost. This makes them a perfect addition to your fall garden. Brussels sprouts are also low in cholesterol and saturated fat and a good source of calcium, fiber, iron, magnesium, phosphorus, potassium, riboflavin, thiamin, and vitamins A and B6. See that. Your mom was on to something when she told you to eat your Brussels sprouts!
Plant collard greens in the early fall so you can harvest them for winter. Plant them in moist and fertile soil in rows at least three feet apart. Collards actually taste better after frost exposure, have many vitamins, and taste great in stir-fries.
Radishes are easy to grow and add color to your salad! Plant them four to six weeks before the average date of the last frost in your area. Sow seeds 1/2-inch deep and one inch apart in rows 12-inches apart. After they sprout, thin to about 2-inch spacings, so they have room to grow. Keep in mind that radishes need sun, so do not plant them in too much shade. Plant them consecutively every two weeks (or so) while temperatures are still cool for a continuous harvest.
One thing to remember is that you'll have to water your planted vegetables. Check out our blog post, Tips for Watering Your Garden, because some may require more water than others. And here's a vegetable planning guide that gives you more ideas on what to plant in the fall.
Perennials can live for more than two years, and they're less work than annuals that only grow for one season. For instance, hostas can be divided and replanted. Peonies don't require much work and can be planted or transplanted in the fall. They thrive in a variety of climates and soil and need partial to full sun. To grow peonies, avoid planting them too deep. Water them carefully (at least one time each week) until your ground freezes, but avoid overwatering.
Snowdrops are delicate bell-shaped flowers that face downward on thin green stems. Plant (mix a garden fertilizer rich in nutrients into the soil) them in groups under deciduous trees such as oak, maple, hickory, and white ash, so they get sunlight in the spring and shade in the summer when they go dormant. You may also plant snowdrops around evergreens or in open spaces in a rock garden or perennial flower bed. Deep freezes and snowfall don't affect them, they multiply easily, are deer-resistant (instant pest control) and can handle the shade or full sun.
If you want a colorful spring, plant hardy fall bulbs such as anemone, crocus, daffodil, hyacinth, iris, and tulip because they can tolerate the cold. To create a unique look, plant several varieties with different bloom times and enjoy their beauty throughout spring.
Would you like to reduce your water bill? Then here's what to plant in the fall: low-water grass. If you live in the North, fertilize bluegrass, ryegrass, or a fescue blend like Eco-Lawn in early September and in late October. If you live in the South, don't feed dormant warm-season grasses such as Bahiagrass and St. Augustinegrass. Till your soil eight inches deep, top it with a three to four-inch layer of compost (you may use organic), till again, water thoroughly, let the soil settle for a few days, and then sow your grass seed.
As for trees, you may plant buckeye, crabapple, hawthorn, elm, maple, pines, sycamore, spruces, and ash in the fall. The types of shrubs you can plant in the fall are oakleaf hydrangea, rhododendron, smoke bush, spirea, and Camellia sasanqua. If you plant a slope or hillside, create a berm (mounded hills of dirt) on the declining side of tree or shrub because it will catch rainwater and any runoff as it moves downhill.
Fall is an ideal time to plant trees and shrubs because the weather is cool and the soil is still warm for roots to develop. But before you start digging and planting, contact your local utility companies so that you don't dig up an underground line. Dig a hole two to three feet wider than the plant or shrub root ball, so the roots have plenty of room to grow. Water them until the ground freezes in your area to ensure they have a good start before going dormant during the winter. Also, add a two to three-inch layer of mulch around the base of shrubs to ward off any weeds and ensure that the soil retains moisture.
Fall Planting: What Will Be in Your Garden?
Now that you know what to plant in the fall, the only decision you have to make is what actually to plant. You may want to determine your "hardiness zone" because it can help you decide what to plant in the fall. To discover your zone, use the USDA Hardiness Zone Map. Enter your zip code, and the results will show your hardiness zone along with what you may plant and when. However, the hardiness zone map should be used as a guideline because the weather is fickle. There may be years when the planting season is extended so that you may plant more veggies, trees, shrubs, and flowers than you thought possible. Use your best judgment. Happy planting!


In my search for resources to sharpen my MEAN full-stack skills, I found this great book, "Getting MEAN with Mongo, Express, Angular, and Node" by Simon Holmes. Published in 2016 by Manning Publications, it is the most relevant and up-to-date resource I have found.
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text:
Ohio Events
Indiana Events
Kentucky Events
Michigan Events
West Virginia Events
National/Regional Events
Trade Blanket
(These dates are tentative, depending on the status of the pandemic. Please register or check with the organizer before making plans to attend.)
Vicki@RendezvousOhio.com
March 4-6, 2022 - Seven Years' War Inc. Annual Congress & Gala, Spring Mill Inn, 3333 Indiana 60, Mitchell, Indiana. Contact Facebook page. The event is a combination educational conference and annual business meeting for SYW Inc. members and fans of history from around the world. Friday evening social gathering. Saturday, educational presentations and meeting. Saturday night, banquet and trivia night. Sunday checkout.
March 5-6, 2022 - Old Town Trade Fair, Assembly Hall, Greene County Fairgrounds, 120 Fairground Road, Xenia, Ohio. Contact Tim and Sharon Milligan, stitchersm@aol.com, 937-857-9745 or Facebook page. Open 9 a.m.-5 p.m. Saturday and 9 a.m.-3 p.m. Sunday. Admission $4 per person; children 11 and younger free. Food available on site. Reenactors, dealers, collectors, educators, craftsmen and history buffs welcome. Wares must pre-1890 originals or reproductions.
March 12-19, 2022 - Southwestern Regional Rendezvous, Nocona, Texas 76265. Facebook page, www.facebook.com/southwesternrendezvous. Contact Ty Brady, 830-624-9447, or Jason Booher, 972-670-3633. Camp fees if registered before Feb. 17 are $25 ages 13 and older, $5 ages 12 and younger, $20 for mug, $10 per medallion, $70 for trader and $45 for blanket trader. Trader fees include one adult. Add $10 to adult and trader fees after that date. Early setup March 9-11. Long term, short term, horse camp, modern camp. Public days March 12, 13 and 19. Competitions include shoots, archery, hawk & knife, cooking contest, Highland games, kids' games. Seminars and colleges.
March 19, 2022 - Pontiac's War Symposium, Bushy Run Battlefield, 1253 Bushy Run Road, Jeannette, Pennsylvania. Tickets are $35-$75 at www.eventbrite.com/e/pontiacs-war-symposium-tickets-218776194487 or register at the museum during business hours, 724-527-5584. One-day symposium with historians and an author from various places to discuss the causes, events and affects of Pontiac's War on American history.
May 14-15, 2022 - Across the Centuries timeline event, Fort Loudoun Historic Site, 1720 N. Brooklyn Road, Fort Loudon, Pennsylvania 17224. Contact Mike Strausner, president@FortLoundounPA.com, 717-372-5945. Registration requested by April 23. Time periods such as Ancient Romans and Greeks, Vikings, medieval archers and soldiers, Irish militia of the 1600s and Scottish Highlanders along with military and supporting impressions of the 18th, 19th, 20th and 21st centuries. Open to public 9 a.m.-5 p.m. Saturday and 9 a.m.-2 p.m. Sunday. Visitor admission is $5.
March 19-20, 2022 - Kalamazoo Living History Show, Kalamazoo County Expo Center, 2900 Lake St., Kalamazoo, Michigan. Sponsored by Yankee Doodle Muzzle Loaders Inc. Contact Leslie Martin Conwell, 765-563-6792, kalamazoolivinghistoryshow@gmail.com, www.KalamazooShow.com. The largest juried show in the Midwest devoted to pre-1890 original or reproduction living history supplies, accoutrements and related crafts. Also, educational programs, craft demonstrations and children's activities. Open 9 a.m.-5 p.m. Saturday and 9 a.m.-4 p.m. Sunday. Admission $7 for one day; $10 for weekend pass. Children 12 and younger free with an accompanying parent. Vendors are invited to email kalamazoolivinghistoryshow@gmail.com for an application.
March 31-April 3, 2022 - School of the Longhunter, Prickett's Fort, 88 State Park Road, Fairmont, West Virginia, 26554. Contact (304) 363-3030 or register here. Intense weekend of instruction, exploring the role of early frontiersmen on the American frontier. Speakers focus on frontier skills of the longhunter. Space is limited and registration is required. Fee is $40 for members/$45 for non-members.
April 22-24, 2022 - Spring Thaw Rendezvous, Ball & Arrow Primitive Weapons Club, 5190 Days Lane, New Philadelphia, Ohio. Contact Jeff Maluski Jr., 330-343-5041, www.ballandarrow.org, Facebook page. Camp fee $20. Competitions include woods walk, bow trail, hawk & knife, kids games. Take your own drinking water. Walk-ins welcome. No pets.
April 22-24, 2022 - Bridgeton Rendezvous, Downtown Bridgeton, Indiana 47836. Sponsored by Bridgeton Covered Bridge Association. Contact celiacase@hotmail.com, 765-548-2093 for camping information, bridgetonindiana.com. Reenactment 1750-1840 with period camps, clothing, cooking, trading, black powder rifle shoots, primitive bow shoot, knife and hawk throwing demos, woods walk, canoe event. No camp fee. Rustic setting and historic town. Free space for indoor period trade fair vendors. School day Friday. Early setup by arrangement.
April 23-24, 2022 - Patoka Valley Long Rifles Spring Rendezvous, 1579 E. Logtown Road, Winslow, Indiana 47598. Contact Tom E Hawk Mosley, 812-677-2318, patokavalleylongrifles@gmail.com, Facebook page.
April 27-May 1, 2022 - Lancaster County Longrifles Rendezvous And Black Powder Shoot, Muddy Run Park, Susquehanock Drive, Holtwood, Pennsylvania. Contact Danny Gichner, 717-682-1393, gich@comcast.net, or Luanne Bell, 717-566-9983, luannebell56@gmail.com, www.lancastercountylongrifles.com, Facebook page. Pre-1840 fur trade era. Camp fees are $35 for adults ages 17 and older and $27 for youth ages 12-16 (subject to change). Children ages 11 and younger are free. Sutler fee is $25. Adult day shooter is $35 and youth day shooter is $27. Registered sutlers may set up April 24. Early setup for campers is 8 a.m.-8 p.m. April 26. Period attire is required beginning at 8 a.m. Wednesday. Gate is open for registration 8 a.m.-7 p.m. Wednesday, Thursday and Friday and 8 a.m.-noon Saturday with a one-hour unload time. Camp ends at noon Sunday. Small modern camp available and nearby campground. Competitions include rifle, pistol, smoothbore shoots as well as archery, hawk & knife, woods walk, children's games, Highland games, seminars.
(New location) April 29-30, May 1, 2022 - Grassy Run Heritage Rendezvous, Grassy Run Historical Arts Committee, Cook Log Cabin Heritage Center, 6707 Goshen Road, Goshen, Ohio 45122. Contact 513-675-3934, grassyrun@gmail.com, www.grassy-run.org or Facebook page. In partnership with Goshen Township Historical Society and Goshen Schools, the historical Cook Log Cabin is to be open and a period blacksmith shop operating in addition to all of the past demonstrations, activities, music and vendors. Main camp on ground of Goshen High School with access from its parking lot. Friday school day.
May 11-15, 2022 - NRLHF Corps of Discovery, Nichols Family Farm, 85 TR 1305, Toronto, Ohio. Contact Mark Rebres, 740-632-8625, 1snake97@gmail.com, www.nrlhfcorpsofdiscovery.com. Free public admission 9 a.m.-4 p.m. Thursday-Saturday. Setup Wednesday. A learning rendezvous, seminars, workshops, educational sessions. Masonic Beaver Rendezvous is during the event this year. Archery, hawk & knife and shooting demonstrations. Modern tent camp area for beginners interested in participating. Artillery on request; call ahead. Some room for horses and mules. Advance registration ends 21 days before start of event. Advanced registration fees are $20 per adult for NMLRA members; $25 for non-members. Children ages 17 and younger are free. No trader fee. Registration refunds must be requested in writing at least 21 days before the event begins. No refunds after the event. No pets; NRLHF follows ADA regulations. For more details on fees and rules, visit www.nrlhf.org.
May 21-22, 2022 - Terre Haute Colonial Fair, 10382 Grotto Road 47805. Juried event in time period 1750-1812. Vendors should contact Robert Shelley, gizzy7106@gmail.com, and citizens and military should contact Ron Turner, rdknturner@aol.com, 317-879-6615. For electronic registration, contact klbullington15@gmail.com. Woodland Native encampment, longhunter camp out and in the woods, hide tanning demonstrations, military demonstrations to include firing of muskets and artillery, demonstrating craftsmen, shopping, entertainment, food. Woodland battles are planned both days where the public can observe and experience the tactics of the 18th and 19th centuries. History of Vigo County, Indiana. Participant breakfast is $5, all you can eat. Early setup starts at 10 a.m. Friday. Showers. Public hours 9 a.m.-5 p.m. Saturday and 10 a.m.-4 p.m. Sunday. $5 admission.
May 27-30, 2022 - Sons of Liberty Spring Rendezvous, Canters Cave 4-H Camp, 1362 Caves Road, Jackson, Ohio. Contact Norman Garringer, 740-773-3891, normanga@roadrunner.com. Pre-1840 rendezvous with black powder shoot, hawk and knife and primitive archery competitions. Potluck dinner Saturday night for paid campers only. Friendly event and newbies welcome.
June 10-12, 2022 - Old Mill Village Black Powder Rendezvous, Old Mill Village Museum grounds, 5774 SR 848, New Milford, PA 18834. Contact Tim Button, 570-434-3353, button2071@gmail.com. Target shooing, woodwalk, hawk & knife. Camp fee $5 per person ages 12 and older; $2 for ages 5-11. Pre-1840 attire required. Sutlers and merchants welcome. Primitive and modern camps. Food and ice available. Modern restrooms. Public welcome noon-5 p.m. Saturday.
June 18-19, 2022 - Prelude to Revolution - The French and Indian War, George Rogers Clark Park, Springfield, Ohio. Sponsored by George Rogers Clark Heritage Association and King's American Regiment / Allison's Company of Kentucky Militia. Juried event that portrays 20 years before the outbreak of the American Revolution when the Ohio Country was part of the French Empire and the homeland to Native peoples. Site of the 1780 Battle of Peckuwe and the venue of the annual Fair at New Boston. Admission $5 for ages 16 and older.
July 29-31, 2022 - Gunmakers Fair at Kempton, Kempton Community Center, 83 Community Center Drive, Kempton, PA. (Near Dixon's Muzzleloading Shop where the event took place for 37 years.) Information at https://gunmakersfair.wixsite.com/gunfair or www.facebook.com/GunmakersFairKempton. Seminars, gunmakers, artisans, horners, reenactors, vendors of 18th and 19th centuries. Rifle and accoutrements judging and awards. Open 9 a.m.-5 p.m. Friday and Saturday and 9 a.m.-3 p.m. Sunday. Admission $5 per person ages 16 and older; 15 and younger free.
Aug. 11-14, 2022 - Living History Encampment at the Henry County Fair, Napoleon, Ohio. Contact Taylor Moyer, 419-906-1660. Time periods are French and Indian War through American Civil War. Setup Wednesday evening. Camp is between historic buildings including the 1897 One room Schoolhouse, c. 1910 Historic Gazebo, 1860s Log Home. Saturday night meal. Limited space for camp sites and demonstrations. Event is during the county fair so not a typical encampment experience.
Sept. 16-18, 2022 - Colonial Market Days, Abner Longley Park, 1601 Longley Dr., Lebanon, Indiana 46052. Contact (317) 762-0117, https://colonialmarketdays.com application form. Colonial merchants, demonstrators and craftsmen. Military units and tacticals. Entertainment such as jugglers, street performers, magic and music.
Sept. 23-Oct. 1, 2022 - NRLHF Eastern Primitive Rendezvous, 3021 Locust Road, Milan, PA 18831. Contact booshway Rose Pruyne, Eastern2022@gmail.com, or scribe Beverly Heister, flintlocktulle@gmail.com. Early setup is 8 a.m.-5 p.m. Sept. 21-22. Public days 10 a.m.-4 p.m. Sept. 24-25. School day Sept. 27. Advanced registration ends Aug. 23. Advanced registration fees are $55 per adult for NMLRA members; $65 for non-members. Children ages 17 and younger are free. Registration at the gate is $10 more per person. Non-registered campers pay a $5 per day early setup fee. Trade fee $50; commercial blanket trader $20. Registration fee refund fee is 20% of the fee. No pets permitted. NRLHF follows ADA regulations. For more details on fees and rules, visit www.nrlhf.org.
Oct. 14-16, 2022 - Sons of Liberty Fall Rendezvous, Canters Cave 4-H Camp, 1362 Caves Road, Jackson, Ohio. Contact Norman Garringer, 740-773-3891, normanga@roadrunner.com. Pre-1840 rendezvous with black powder shoot, hawk and knife and primitive archery competitions. Potluck dinner Saturday night for paid campers only. Friendly event and newbies welcome.
Oct. 22-23, 2022 - Patoka Valley Long Rifles Fall Rendezvous, 1579 E. Logtown Road, Winslow, Indiana 47598. Contact Tom E Hawk Mosley, 812-677-2318, patokavalleylongrifles@gmail.com, Facebook page.
4636 County Rd P
McClure, OH 43534


text:
Q: IoT edge module fails to start on kubernetes I can't seem to be able to deploy a module that works on a stand alone deployment on a Kubernetes edge.
Is there anything special that needs to be done in the module?
Error thrown is as follows (thrown when trying to create hub client):
Error: connect ECONNREFUSED 127.0.0.1:35001

at TCPConnectWrap.afterConnect [as oncomplete] (net.js:1141:16) {

errno: 'ECONNREFUSED',

code: 'ECONNREFUSED',

syscall: 'connect',

address: '127.0.0.1',

port: 35001

}

Can someone help me? Thanks!


As a healthy oasis of farm-fresh food in the city hub, it was important for Bird on a Wire's first full dining space to provide earthy elements to anchor its presence in the middle of the industrial chic framework of Ponsonby Central.
Building upon existing themes and a sunny central palette of bright gold, the new space weaves farm-style elements with modern shapes and textures. The result is a softened, organic take on fast-casual: fresh, honest food served in a fast-paced but comfortable haven.


Softech Logix is an Information Technology solution provider company that provides Web Designing, Custom Software Development, Web Development, Mobile Application Development, Internet Marketing i.e. SEO, SMO, PPC & all Information Technology Solutions.
Creating a strong online presence is a tough challenge in today's world. In Softech Logix, we understand the value and requirements for any website presenting in this IT industry. Our services give one door answer to all the needs. The company's employees help you in the progress of your business, & develop a solution that would fully communicate to your business needs and requirement. We believed in providing our customers with best price, best quality, best reliability and affordable solutions.


We have a personal trainer in Little Rock that is ready to help you reach your fitness goal, whether it's to lose weight, build muscle, rehabilitate from an injury, increase flexibility, increase endurance, improve overall health or improve sports performance.
Find My Trainer has a wide selection of Little Rock in home personal trainers that will work within your busy schedule. A Personal Trainer will train at your home, facility, office or the outdoors, making it as convenient as possible to reach your fitness goals.
We'll do everything in our power to provide you with peace of mind. If you are ready to make the life change, Find a Personal Trainer nearby Little Rock, Arkansas.


The Brazilian division of Samsung gave a spin in social networks. In Twitter, a post was published that was accompanied by a photo allegedly made on the front camera of the Galaxy A8 smartphone. But attentive users found the original picture in the store of stock photos Getty Images.
The original photo was taken in 2015 and signed as "Portrait of a beautiful pair of hipsters, which looks happy." Also in the Brazilian account Samsung was found another photo from the photo shoot, which was used as a photo on the Galaxy A8. In total, for their use, the company paid Getty Images $ 998.


Creating your first household from the ground up is a very rewarding experience. It gives you the opportunity to have complete control over your house and allows you to tailor it to the needs you have now and the ones to come. While it is a great and rewarding experience, everyone knows that it isn't an easy task and normally brings with it a lot of stress.
It doesn't have to be a gruelling task however. We have got a couple of tips for you to help the new home builders in WA start their dream house.
Planning is a very important step with a lot of big decisions and projects. You want your layout to be both functional and aesthetically pleasing which is why it is important to have a plan laid out before you get stuck into it. You should consider the orientation of your home as well as the types of lighting and amount of power points you will have.
There are hundreds of little things that you take for granted every day that should be considered. There are many helpful online tools out there to help you with your plan and creates a mock floorplan.
A great tip for new home builders in WA is to overestimate how much you are going to spend on your project. No matter how much you think it is going to cost you should add some more onto that just to be safe. There are many things that aren't included in quotes as well so putting something aside for that inevitably happens is highly recommended. Internet cables and window coverings are common items that get overlooked during this process.
Before you get started and hire any company off the street you want to ensure that they are fully licensed and insured in the event of something going wrong. This will also give you a piece of mind knowing that the new home builder in WA that you have chosen is fully qualified.
Getting references from your new home builder in WA will allow you to see what other people's experience was like with same company or individual. Were they satisfied and if not what went wrong that could have gone better? It is very common to ask for references so you shouldn't feel awkward about asking for them before you sign a contract. Additionally you should take this time to see what the warranty for their service is and whether it will be applicable to your situation.
Look through their past work closely to see what you like and don't like about it. Each type of constructor has their own style and it shows the most through their previous jobs. If you are a new home builder in WA you should be certain that the company you are going with has the same style sense as you otherwise you may be left disappointed.
We mentioned it before but you will be working with this person for a long time so making sure they have a personality that you get along with is crucial.


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Everyone has those days - the house is a mess, nothing is put away... then the doorbell rings. Ugh! The last thing you want is someone to come in and see the disaster!I have found a few things to keep in mind, for keeping my home guest-ready. Regardless of the day's craziness, I can keep my sanity and not worry as much about drop-by's if I stick to these couple of self-imposed rules.


With the imminent release of a new single Al Lupo (April 20) and a headline show at Night People in Manchester this Friday (13), we caught up with Hey Bulldog's front man Rob Manton for a chat about the single and the Italian connection, their new material and plans for the rest of the year.
It's been a year or so since we spoke, what's been going on in the world of Hey Bulldog?
It's been a mixture of gigging, writing, recording.
Playing our first European gigs was great last summer we always really enjoy playing on the bigger stages, we've got new songs that we're still developing and the first couple of months of the year we've been playing some really good gigs building up to the new single release.
You've got a new single out on April 20th called Al Lupo, could you tell us a little about the song please and why the title of the song is in Italian?
We were playing a festival in Sicily in August so 'In Bocca Al Lupo' (Into the mouth of the wolf) was a phrase people would say to us as performers meaning good luck, the music for the song came from the very first jam we had when we got back from the trip, so the energy of the music and the metaphor of the saying seemed to fit perfectly to some up what that whole experience meant.
You're also headlining Night People on April 13th. You've played a lot of support slots recently. Does it feel good to be doing a headliner of your own?
Yeah we love playing support slots with good bands, people like The Lucid Dream, Sextile and The Schizophonics but with the single coming out we wanted to do something a bit more focused on us, so we put together the lineup with The Empty Room guys at Night People in Manchester and got some great bands like Deja Vega and Freakout Honey to play with us.
Will you be playing new songs?
Having the keyboard now has definitely opened up a new creative door into what we can do as a three piece, so it will probably appear in more songs, No future (part ii) does seem to have become a live favourite too and with it being a mostly instrumental track it wasn't something you would have naturally predicted, so I'm sure the seeds of the song will take root in other things we do.
We're always looking to develop and keep our own identity, there's so many bands that just sound exactly the same or pale comparisons of their one or two main influences.
Originally part of the reason for naming the band after a Beatles track was to be in a band that was capable of doing a wide range of really good songs and taking different directions in a natural progression.
What have you got in the pipeline for the rest of 2018?
We've got some exciting festivals and bigger support slots coming up for the summer, another single release with some more headline shows. We're talking to labels so possibly doing a full album would be nice too!


text:
Q: Dataframe iteration better practices for values assignment I was wondering how to make cleaner code, so I started to pay attention to some of my daily code routines. I frequently have to iterate over a dataframe to update a list of dicts:
foo = []
for index, row in df.iterrows():
        bar = {}
        bar['foobar0'] = row['foobar0']
        bar['foobar1'] = row['foobar1']
        foo.append(bar)

I think it is hard to maintain, because if df keys are changed, then the loop will not work. Besides that, write same index for two data structures is kind of code duplication.
The context is, I frequently make api calls to a specific endpoint that receives a list of dicts.
I'm looking for improviments for that routine, so how can I change index assignments to some map and lambda tricks, in order to avoid errors caused by key changes in a given dataframe(frequently resulted from some query in database)?
In other words, If a column name in database is changed, the dataframe keys will change too, So I'd like to create a dict on the fly with same keys of a given dataframe and fill each dict entry with dataframe corresponding values.
How can I do that?

A: The simple way to do this is to_dict, which takes an orient argument that you can use to specify how you want the result structured.
In particular, orient='records' gives you a list of records, each one a dict in {col1name: col1value, col2name: col2value, ...} format.
(Your question is a bit confusing. At the very end, you say, "I'd like to create a dict on the fly with same keys of a given dataframe and fill each dict entry with dataframe corresponding values." This makes it sound like you want a dict of lists (that's to_dict(orient='list') or maybe a dict of dicts (that's to_dict(orient='dict')—or just to_dict(), because that's the default), not a list of dicts.

If you want to know how to do this manually (which you don't want to actually do, but it's worth understanding): a DataFrame acts like a dict, with the column names as the keys and the Series as the values. So you can get a list of the column names the same way you do with a normal dict:
columns = list(df)

Then:
foo = []
for index, row in df.iterrows():
    bar = {}
    for key in keys:
        bar[key] = row[key]
    foo.append(bar)

Or, more compactly:
foo = [{key: row[key] for key in keys} for _, row in df.iterrows()}]


We create branded mobile applications that get featured in the Play Store. With in-house developers and design strategists, we help you turn your mobile concepts into a reality, along with robust performance, stunning design and an awesome user experience.
We develop Android applications which are supported in all android devices and devices. Moreover we are efficiently designing Hybrid Applications to support all platform whether it is Android or IOS. Our App Developers are fluent enough to design complex Cross-platform Apps with crisp & beautiful designs which are easy to use.
We treat every project individually and do thorough research before moving to the designing phase with client approval. Whether it is Android App development or iOS app development services we are one of top choices for our clients because we deliver experiences.
Our android apps are stacked with user-friendly features to uplift your business. We cover up the entire application development cycle, from concept making to distribution. Applications are developed by future-proof technology that comprehends all the significant aspects and encompass complete range of android devices.
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Our hybrid app developers provide solutions that work seamlessly across all platforms and operating systems, whether smartphone, tablet or PC running Android, iOS, or Windows. We use proven methodology to streamline projects to match your goals, timeline and budget.
We make flexible cross-platform apps to run across multiple operating environments like Android, iOS or Windows with high performance, unique functionality, engaging UI/UX and user-friendly modules. Our process causes development and maintenance of the app easier and faster, eventually reducing the cost.
We create branded mobile applications that engage your customers.


text:
Q: How to remove ONLY alphanumeric characters with number notepad++ i need help for remove non alpanumeric characters on notepad++ with number into non alpanumeric characters, please see example:
ZTE Blade L3 (4)

ZTE Blade Spark (23)

ZTE Blade V7 (5)

ZTE Blade V7 Lite (6)

ZTE Blade V8 (14)

ZTE Blade V9 (3)

and after remove :
ZTE Blade L3

ZTE Blade Spark

ZTE Blade V7

ZTE Blade V7 Lite

ZTE Blade V8

ZTE Blade V9

A: Assuming the numbers in parentheses would always occur at the end of each line, you may use the following find and replace, in regex mode:
Find:    \s+\(\d+\)$
Replace: (empty)

Demo


text:
lang:   PT-BR
title:  Ficando na Fila
answer: ^\[([-\.\d]+)(\s*,\s*[-\d\.]+){3,}\]$
ok:     Excelente
error:  Tente incluir um quarto número na lista
---

Listas (arrays) guardam coisas __em alguma ordem__.

É como ficar na fila para a pipoca. Você está atrás de alguém e você nem sonharia passar a frente dele,
certo? E o cara atrás de você, você está de olho nele, certo?

Aqui está uma lista para você. Números de loteria.

    [12, 47, 35]

Tente adicionar um número a esta lista: digite uma virgula após o 35, então digite um número. O espaço é opcional.

redpajama_set_name: RedPajamaGithub


text:
Q: Circa 60's or 70's film about a woman who steals a dead womans ring and the dead woman rises and comes floating after her I have been searching for this film for decades. I believe it is late 60's early 70's.  As a woman lies dead, another woman, possibly an attendant or relative, steals a ring from her finger. Afterwards the woman rises up and floats after her to get her ring back. This film scared me stiff, unusually scary for its time.

A: It should be Black Sabbath (1963), in particular the third story, named "The Drop of Water".
From Wikipedia:

In London, England, Nurse Helen Chester (Jacqueline Pierreux) is called to a large house to prepare the corpse of an elderly medium for her burial. As she dresses the body, she notices a sapphire ring on its finger. Chester steals it, [...] Chester finds the woman's corpse lying in her bed. It rises and floats toward her.


Hedgehog Development and Microsoft invite you to learn how to succeed at building better software at our Application Life-cycle Management (ALM) Executive Roundtable at Microsoft's offices in Hauppauge, NY on Thursday, January 29, 2009 from 9:00 AM to 12:00 PM. Registration is required as seating is limited. Hedgehog will discuss how ALM and Microsoft's ALM solution, Visual Studio Team System (VSTS), can help put the odds in your favor for your next software project. This is a great opportunity to discuss amongst peers and subject matter experts the challenges around the SDLC.
For more information please contact Dianne Cali at dcali@hhogdev.com or call 631-676-2186 x360.


Chris Brown goes three for three in releasing consecutive music videos this week, this time for "Anyway" featuring Tayla Parx.
For this clip, the narrative follows a woman who, fed up with her man's antics, decides to take up a stranger's offer on a date. But when he doesn't show up to the restaurant, she instead meets her friends at the club, where the R&B heartthrob sees her enter. He ends up being the boyfriend from the start of the visuals, and the two inevitably reconcile on the dance floor.


It's common in aurora circles to talk of aurora seasons. And in many ways this makes sense - not because the aurora actually stops happening during a few weeks in the midst of June, in the same way that the season of Spring ends and gives way to summer. Rather it's simple because it really doesn't get dark enough. As we get closer and closer to summer solstice, twilight hangs on longer and longer until eventually the northern horizon never moves beyond dusk into night proper. So even if there was an aurora happening, it would be unlikely to be able to shine through the ambient brightness, and distinguishing between it and the twilight sky would be nigh on impossible. It would have to be an aurora of unusually large size to do that. And those are not very common.
In fact, I thought I was pushing it when I caught this lovely little show at Slemish, Co Antrim on 12th May this year. An aurora? In May?!? This was taken around midnight, and even then in mid May the sunset glow and evening dusk were still there. In fact, it was only the presence of the tell tale pillars of light that really confirmed for me that the aurora was happening.
That would be it for the 2014/15 season, I thought. It was nice to fit one last aurora viewing in, but now focus would shift towards noctilucent season (which have a season in the literal sense, only being visible for a few months from mid May to Mid July).
It would take a solar storm of unusual size to change that. And on 22 June, the day after the longest day of the year - when viewing conditions for the aurora are at their worst in terms of the sky getting truly dark - the aurora delivered just that.
But region 2371 was far from done. For on Sunday 21 June, summer solstice itself, it emitted a double M-class solar flare which fired out a CME. But a full halo CME, this time. And that meant one thing - this CME was coming straight towards us. As Space Weather Live reported it, 'no chance of a glancing blow here - this even won't miss our little planet.' Excitement was now beginning to build in the aurora chasing world. The CME was heading to us quickly, and expected impacts put it around 18.00 hours on Monday. Could this be the one to do it? Could this CME punch through the dusk of twilight?
Region 2371, photographed from my drive way on Tuesday 23 June. It the largest sunspot region I've photographed to date.
Just after dinner time on Monday, I took my camera out into the garden. The skies were clear, and the sun was blazing overhead. I put my homemade Baader filter on to my zoom lens and took some images of the sun. I was keen to capture that wonderful sunspot region in all its glory. And indeed I did. But, as I was taking this very picture, the CME from 21 June was impacting our atmosphere. And amazingly this region had just fired off yet another solar flare, peaking at M 6.6. What a busy little sunspot region this was being!
The stats from the ACE satellite were responding to the arrival of the CME just before 18.00 UTC (19.00 BST). The speed of the solar wind jumped from 400 km/s to over 700 km/s. It's temperature and density jumped upwards. And the magnetic field responded too - the Bt (its density) jumped upwards and crucially the Bz (its orientation) dropped dramatically southwards to a staggeringly low value of -40. This was big. The forecasts were predicting very high storm potential during the next number of hours, even as high as Kp 7 or 8. If anything could beat these twilight skies, this bad boy could!
The magnetomoters showed that something very big was under way.
And so it was very much game on. Although there was still a very long wait until the darkest hours around 01.00 on 23 June. The skies were clear and the forecast was good (if cold) and I headed for a favourite location back to Slemish just before sunset at around 21.00 hours. But as I was waiting there, some clouds began to close in, spoiling my sunset view. In fact, over the next few hours, the cloud thickened and the skies above and to the NW became obscured. Around 23.00 hours, my photography buddy Alistair White had arrived to join me, and we made the decision to leave Slemish and head for the coast. There was a gap just visible there, so it seemed like our best shot. Just before we left, I checked the magnetometers. They were going mad so the signs remained very positive!
Twenty minutes later we were standing on the beach at Glenarm. The wind had died down, the waves were gently lapping at our feet and the skies above were clear. The golden glow of sunset clung in a band along the north eastern horizon, and above it the deep blues of dusk stretched far up into the sky. It wasn't dark. It wasn't ever going to get fully dark. But we lived in hope that this aurora would deliver the goods. We had no 3G signal were we were, so tonight it was going to be old school - determination and patience to stick it out in the hope that something would happen!
And it didn't take long. Just after 23.00 hours, a small but perfectly formed noctilucent cloud display developed to the east. As the skies got gradually and ever so slightly a deeper blue, the shimmering whites of these glorious clouds became evermore distinct. I set up my camera for some time lapse shots. He we were - two mates, standing on a beach in deepest midsummer, enjoying a cool (non-alcoholic!) beer, while watching a delightful NLC display. Even if the aurora didn't deliver, this was still going to be a good night.
And so the hours passed while we waited. My eyes were scouring the skies above, my mind playing tricks on me, convincing me I could see faint pillars of light. But every time I thought I saw something, I realised I was imagining it.
Until 00.50 hours, that is.
I was shooting a close up time lapse of the NLCs to the east with my zoom lens when I thought I glimpsed a ray of light to the north. Closer scrutiny confirmed my initial thoughts this time - the auroral substorm had arrived and the pillars of light were here!
I quickly fumbled around to change my lens from the 300mm zoom to the 11mm ultra wide. I knew this show was going to have to produce very tall pillars to cut through the twilight, and the 11mm was the best choice to try to fit them in. I got the lens on, fired off a test shot. And, lo and behold, there they were!
For the next half an hour or so, the rays slowly made their way across the sky, from north to east, traversing the twilight zone, cutting through in purple majesty not only the dark blues of dusk above, but mixing with the yellows of sunset to produce the most exquisite green band low in the sky.
I decided to go for some time lapse photos here too, shooting with settings I've never been able to come close to in aurora photography before: f/3.2, 10 seconds and ISO 100 (yes ISO 100!!) For the first 10 minutes, the display was clearly visible to the naked eye (although without the colour). For the remaining 20 minutes or so, it died back a bit and was just about visible if you looked hard enough. At this stage, my enthusiastic leaping around attracted the attention of four young people who were out for a night's camp on the beach. They left their fire and came over, curious as to what was going on. When I explained it to them and showe them the pictures, they were stunned. It was their first aurora - it's always a delight to share that experience with anyone.
Of course, we stayed on for about another 45 minutes or so, to see if anything else might happen. But by now it was after 02.00, and the light of dawn was building again. It was time to call it a night. We went home gorged on the experience, tired but happy at another successful night's aurora hunting.
It was a dream fulfilled. A massive aurora had arrived, when the skies were clear of cloud, and it peaked at just the time when the skies were at their darkest above us. We were living the dream - the 'out of season' midsummer's night dream no less!
As a postscript, this storm proved to be indeed a big one, the biggest since St Patrick's Day 2015, which itself was the second biggest solar storm in this solar cycle. I was standing at more or less the same place I was when that storm hit, so it might be interesting to see some comparisons of the shots - and a hint of what we would have seen on 22 June if we had been in midwinter and not midsummer!
The K indices for the UK magnetometers during the CME impact. It was a big show indeed!
Sunspot region 2371 gave off multiple solar flares and CMEs and produced some great aurora displays in the southern hemisphere where they were experiencing mi-winter. As a tribute, Space Weather Live put together this awesome time lapse video of its transition across the face of the sun.
A quick update on the current geomagnetic conditions.We are still experiencing the effects of today's coronal mass ejection arrival but the impact has been rather insignificant compared with what was forecast.While the solar wind speed remains high around 600km/s, the strength of the IMF declined from an initial value of 12nT to 9nT right now with the direction (Bz) being mostly northward. These kind of values are really insignificant and we can unfortunately conclude that it is even unlikely that we will reach the minor G1 geomagnetic storm threshold. Auroral displays will be confined to high latitude locations. A shame as this looked like a promising coronal mass ejection on LASCO but it turned out to be a disappointment for auroral activity here on Earth.Nonetheless we thank you for following us the past few days. It was a very interesting week thanks to sunspot region 2371 which gave us the second strongest geomagnetic storm of this solar cycle.Unfortunately we have to conclude that sunspot region 2371 is decaying and it is right now only a shadow of it former self. It's delta structure is no longer there as it has ripped loose from the trailing sunspot region. The chance for even a low-level M-class solar flare is very low. To honor this sunspot region that gave us this exciting week we made a time lapse video with SDO footage showing how this sunspot region evolved from June 16 when it appeared at the limb until right now. We also show the M2.0/M2.6 solar flare that launched the full halo CME which was responsible for the severe G4 geomagnetic storm on 22 and 23 June.Thank you for your support and keep following us!


retailers are required to obtain explicit informed consent from customers for any benefits that apply for a fixed period.
We have released a consultation notice which outlines the Minister's request, provides information about the regulatory environment, and invites submissions from stakeholders on the proposed amendments.
While the Minister's request was in relation to the Electricity Code, we are interested in whether stakeholders consider that the issues raised apply equally to the supply of reticulated natural gas, and whether similar amendments proposed by the Minister for the Electricity Code should be made to the Gas Industry Code.
Submissions close on 4 January 2014.


Deep in the fertile Yungas region of Bolivia, where the foothills of the Andes meet the Amazon basin, a small community has staked its future on a foreign plant. When the first tea seeds were brought to the village of Chimate over 50 years ago, the people set aside cultivation of their traditional staple, coca, and looked to tea as their future. The industry collapsed twice, but the people persisted, refusing to abandon their newly-adopted crop. Today, with the help of a remarkably successful USAID project, the burgeoning Bolivian specialty tea industry is within arms reach of economic sustainability.


10 Medical Tests Men Need « CBS Houston.
High blood cholesterol is one of the major risk factors for heart disease.
If you have high blood pressure, you may need medication to control it.
Beginning at age 50 and through age 75, get tested for colorectal cancer.
If you have felt "down" or hopeless during the past 2 weeks or you have had little interest in doing things you usually enjoy, talk to your doctor about depression. .
If you are between the ages of 65 and 75 and have smoked 100 or more cigarettes in your lifetime, ask your doctor to screen you for an abdominal aortic aneurysm. This is an abnormally large or swollen blood vessel in your stomach that can burst without warning.
Local TV news, delivering time-honored solutions to the discerning viewer: Prey for fear.


text:
a-ha interview: "Diplomacy doesn't really work in a-ha"
Seemingly on the verge of splitting for the third time when last year's documentary a-ha: The Movie brought their simmering tensions to the boil, with typical contrariness the band are…
Issue 78 of Classic Pop is on sale now!
In the latest issue of Classic Pop, we have the definitive interview with a-ha's Morten, Magne and Paul who reveal all about their complex band dynamic and new album, True…
Q+A: a-ha: The Movie director Thomas Robsahm
Classic Pop chats to the director of the critically-acclaimed new longform documentary, a-ha: The Movie… By Barry Page The son of actors Ugo Tognazzi and Margarete Robsahm, Thomas Robsahm, has…
a-ha's True North film gets release date
Sony Music Entertainment Premium Content and Trafalgar Releasing have announced the release date for a-ha's forthcoming film True North, the accompaniment to their new studio album of the same title.…
a-ha's first new song in seven years, I'm In
a-ha are back with their first new music in seven years. I'm In is our first taster for their forthcoming album True North, which will be released later this year.…
In the latest issue of Classic Pop we have an exclusive interview with Karl Bartos who reveals all about his life in Kraftwerk. We also serve up an exclusive chat…
a-ha albums – the complete guide
Classic Pop salutes the reluctant teen idols and kings of Nordic melancholia with an in-depth look at the a-ha albums Hunting High And Low Released 1985 Label Warner Bros Just…
Making a-ha: Hunting High And Low
a-ha: Hunting High And Low is one of the finest synth-pop albums of all time, and one of the most successful debuts ever. Here Classic Pop speaks to the band's…
a-ha: The Movie director Thomas Robsahm interview
Since their formation 39 years ago a-ha have established themselves as the most famous and successful Norwegian pop band of all time. Now, their story is to be told in…
a-ha: Living A Three Boys' Adventure Tale
a-ha are the dark, dolorous boy band, One Direction raised on Joy Division and Ingmar Bergman. Not a boy band at all then – just the greatest exponents of soaringly…


text:
Reference Profiles
exRNA and EV Biology
exRNA Biology
EV Biology
Resources and Technology
Publications with Pathways
Additional ERCC Research
pre-ERCC
ERCC Webinars
04.07.16 last updated.
Beyond DNA: TGen points the way to enhanced precision medicine with RNA sequencing
by Roger Alexander
This blog post is adapted from a TGen press release, found here.
Uncovering the genetic makeup of patients using DNA sequencing has in recent years provided physicians and their patients with a greater understanding of how best to diagnose and treat the diseases that plague humanity. This is the essence of precision medicine.
Now, researchers at the Translational Genomics Research Institute (TGen) are showing how an even more detailed genetic analysis using RNA sequencing can vastly enhance that understanding, providing doctors and their patients with more precise tools to target the underlying causes of disease and help recommend the best course of action.
In their review, published recently in the journal Nature Reviews Genetics, TGen scientists highlight the many advantages of using RNA-sequencing in the detection and management of everything from cancer to infectious diseases such as Ebola and the rapidly spreading Zika virus.
RNA's principal role is to act as a messenger carrying instructions from DNA for the synthesis of proteins. Building on the insights provided by DNA profiling, the analysis of RNA provides an even more precise look at how cells behave and how medicine can intervene when things go wrong.
Dr. Sara Byron
"RNA is a dynamic and diverse biomolecule with an essential role in numerous biological processes," said Dr. Sara Byron, Research Assistant Professor in TGen's Center for Translational Innovation and the review's lead author. "From a molecular diagnostic standpoint, RNA-based measurements have the potential for broad application across diverse areas of human health, including disease diagnosis, prognosis, and therapeutic selection."
DNA (deoxyribonucleic acid) sequencing spells out — in order — the billions of chemical letters that make up the genes that drive all of our biologic make-up and functions, from hair and eye color to whether an individual may be predisposed to cancer or other diseases.
RNA (ribonucleic acid) sequencing provides information on the genes that are actively being made into RNA in a cell and are important for cell function. While more complex, RNA holds the promise of more precise measurement of the human physical condition.
There are more forms of RNA than of DNA present in the body, explains Dr. Byron. "RNA sequencing provides a deeper view of a patient's genome, revealing detailed information on the diverse spectrum of RNAs being expressed."
One of the most promising aspects of RNA-based measurements is the potential of using extracellular RNA (exRNAs) as a non-invasive diagnostic indicator of disease. Monitoring exRNA simply takes a blood sample, as opposed to doing a tumor biopsy, which is essentially a minor surgery with greater risks and costs.
"The investigation of exRNAs in biofluids to monitor disease is an area of diagnostic research that is growing rapidly," said Dr. Kendall Van Keuren-Jensen, TGen Associate Professor of Neurogenomics, Co-Director of TGen's Center for Noninvasive Diagnostics, and one of the review's authors. "Measurement of exRNA is appealing as a non-invasive method for monitoring disease. With increased access to biofluids, more frequent sampling can occur over time."
The first clinical test to measure exRNA was released earlier this year, the review said. The test is for use in evaluating lung cancer progression, and the potential for using RNA-seq in other cancers is expanding rapidly. Commercial RNA-seq tests are now available, providing the opportunity for clinicians to more comprehensively profile cancer and use this information to guide treatment selection for their patients, the review said.
In addition, the authors reported on several recent applications for RNA-seq in the diagnosis and management of infectious diseases, such as monitoring for drug-resistant populations during therapy and tracking the origin and spread of the Ebola virus.
Using examples from discovery and clinical research, the authors also describe how RNA-seq can guide interpretation of genomic DNA sequencing results. The use of integrative sequencing strategies in research studies is growing across a broad range of health applications, which promises to drive the incorporation of RNA-seq into clinical medicine as well, the review said.
The paper, Translating RNA-sequencing into Clinical Diagnostics: Opportunities and Challenges, was published online recently in the journal Nature Reviews Genetics. Authors Kendall Van Keuren-Jensen and David W. Craig are participants in the Extracellular RNA Communication consortium.
Source: Translational Genomics Research Institute
New exRNA pathways at WikiPathways
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Targeting exosome biogenesis in cancer: Scientific Reports Top 100
Discovery aids search for cancer biomarkers
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Cancer Exports Molecular Saboteurs to Remotely Disarm the Immune System
A large (scale) advance for small RNA therapeutics
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text:
package apps::protocols::smtp::plugin;

use strict;
use warnings;
use base qw(centreon::plugins::script_simple);

sub new {
    my ($class, %options) = @_;
    my $self = $class->SUPER::new(package => __PACKAGE__, %options);
    bless $self, $class;

    $self->{version} = '0.1';
    %{$self->{modes}} = (
                        'login'            => 'apps::protocols::smtp::mode::login',
                        'message'          => 'apps::protocols::smtp::mode::message',
                        );
    return $self;
}

1;

__END__

=head1 PLUGIN DESCRIPTION

Check a SMTP server.

=cut


You can see the result of optimization in container loading software . You can rotate and zoom within the container loading software , controlling the load pallet after pallet, container after container, in real time.
The container loading software allows you to see display in a virtual environment the load of the container.
The display used is a container loading software where you can move around using the mouse in the direction suits, zoom, and control the process cario pallet after pallet until full container load.
The first pane nelal bar bottom tool indicates the number of containers used for the optimization, and for each container, the number of pallets.


In addition to hot winter drinks, Bariatric Health & Wellness offers healthy alternatives for every meal of the day including dessert. If you are set on taking the first step toward a healthy lifestyle, or you have already been doing so for some time, Bariatric Health & Wellness has just the food supply that you've been looking for. Start eating great and feeling great today!
If you like our low calorie Minestrone Soup, you will be happy to know that Bariatric Health & Wellness offers an endless variety of your favorite foods and desserts, all with a healthy twist to them. From hot cocoa drinks and winter minestrone soup that will keep you cozy in the cold, to other tasty foods such as pizza and enchiladas, you will find it all here. Love the food you eat and the life you live when you shop Bariatric Health & Wellness!
Good taste and blended well.
This is my favorite soup. The taste is very satisfying and keeps me full!!