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1395756 Susy Rami Abdulbaki rabdulbaki@gwu.edu 2021-11-25 03:24:49 2021-11-25 03:24:49
234017 ptizro@coh.org Parastou Tizro No 2021-11-24 04:10:17 2021-11-24 04:10:17
234018 victor.nava@va.gov VICTOR NAVA No 2021-11-24 04:10:17 2021-11-24 04:10:17
234019 mgsilva@ipolisboa.min-saude.pt Maria Gomes da Silva No 2021-11-24 04:10:17 2021-11-24 04:10:17
234020 ascensao4@msn.com Joao L Ascensao No 2021-11-24 04:10:17 2021-11-24 04:10:17
80023 rabdulbaki@gwu.edu Rami Abdulbaki 1 2021-11-24 04:10:17 2021-11-25 03:24:49
80268 jessie.wu@mdpi.com Jessie Wu 2 2021-11-25 05:13:44 2021-11-25 05:13:45
Follicular Lymphoma and Primary Splenic Lymphoma
Subjects: Hematology
View times: 9
Rami Abdulbaki
Follicular lymphoma (FL) is a mature B-cell non-Hodgkin lymphoma derived from germinal center B-lymphocytes (centrocytes and centroblasts) that generally has at least a partially follicular/nodular histologic pattern.
Primary splenic lymphoma (PSL) is a rare malignancy representing about 1% of all lymphoproliferative disorders, when using a strict definition that allows only involvement of spleen and hilar lymph nodes. In contrast, secondary low-grade B-cell lymphomas in the spleen, such as follicular lymphomas (FL), lymphoplasmacytic lymphoma and chronic lymphocytic leukemia/ small lymphocytic lymphoma, particularly as part of advanced stage disease, are more common. Indolent B cell lymphomas expressing CD10 almost always represent FL.
2. Epidemiology of Follicular Lymphoma
PSL comprise approximately 1% of all malignant neoplasms [1][2], when the disease is restricted to involvement of the spleen and hilar lymph nodes. However, a broader definition also encompassing liver, bone marrow or peripheral blood involvement, but lacking prominent distant adenopathy, is accepted as well.
Epidemiologically, one study showed the prevalence of PSL to be approximately 62%, where DLBCL was the most common lymphoid neoplasm (25%) followed by splenic MZL (15%) and FL (6%) [3]. Low-grade CD10-positive lymphoproliferative disorders encountered in splenic specimens belong most frequently to the category of FL (either primary or secondary). However, a subset of FL in the spleen represents aggressive disease (equivalent to DLBCL), considering that extranodal FL is most commonly a high-grade lymphoma that may lack expression (or translocation) of BCL2 [4][5]. However, duodenal-type FL represents an exception to this rule, due to an indolent course and constant expression of BCL2 [6].
The incidence of PSFL is unknown and may be overestimated because the vast majority of FL in the spleen represent secondary disease. In general, PSFL accounts for a small fraction of PSL and only a few case series are available on this entity [7][8][9].
In general, FL has an incidence of 2.1 per in the United States (SEER Follicular Lymphoma—Cancer Stat Facts (https://seer.cancer.gov/statfacts/html/follicular.html, accessed 16 October 2021), and is less common in eastern Europe, Asia and developing countries [10]. FL is 2–3 times more common in white than in black patients [6][11], and disproportionately affects females. The mean age at diagnosis (including all histologic grades) has been estimated to be 68 years, which is similar to nodal FL [7][8][12][13][14]. PSFL is rarely seen in patients younger than 50 years based on case series [7][8][13].
3. Clinical Presentation
Due to the rarity of PSFL, clinical features are incompletely defined. In contrast to nodal FL, most patients present with stage I/II disease [14]. A minority of cases show bone marrow, peripheral blood or liver infiltration [8]. In PSFL, isolated splenomegaly either asymptomatic or accompanied by upper abdominal discomfort is the rule [8]. B symptoms occur in a minority (less than 20%) of cases. Cytopenias (anemia and/or thrombocytopenia) secondary to hypersplenism or rarely due to bone marrow infiltration have been reported [8][13]. In contrast, nodal FL, which may involve the spleen, is usually accompanied by distant lymphadenopathy and more frequent systemic symptoms. The real frequency of PSFL remains to be established. As such, the disease may be incidentally found during work up for other medical conditions [15]. However, pathologic splenic rupture due to massive splenomegaly has been described [16]. Atypical lymphocytosis observed in peripheral blood smears or liver biopsies and/or mild to moderate splenomegaly may be identified incidentally during clinical encounters unrelated to lymphoma work-up in asymptomatic or paucisymptomatic patients. Interestingly, anti-hepatitis C virus (HCV) antibodies were more prevalent in patients with splenic FL compared with nodal FL with splenic infiltration in a study of 17 cases [8].
4. Treatment and Prognosis
Treatment of splenic lymphomas is ascribed to its lineage. Based on a few available studies it has been suggested to treat patients with splenic lymphomas with regimens developed for nodal lymphomas, which is particularly true for FL. However, long term outcome data are unavailable given the rarity of splenic lymphomas. Consequently, specific treatment modalities are not formally recommended for PSFL yet [17].
HCV infection has been more frequently described in PSFL than in nodal FL [8], and anti-viral therapy alone can induce remission of lymphoproliferative disorders [18][19][20], suggesting this option for PSFL.
Stage I PSFL diagnosed on splenectomy specimen could be subjected to an active observation/expectant management strategy, mirroring guidelines for nodal FL stage I treated with complete surgical removal of the affected lymph nodes [17]. Long treatment-free intervals may be achieved by this approach, while minimizing therapy-related adverse effects. A recent large case series of splenic lymphomas undergoing splenectomy demonstrated that additional chemotherapy after surgery did not impact overall survival (OS) in FL [14], further supporting the practice of expectant management. However, the management of stage I nodal FL remains mired in controversy. While current guidelines still recommend localized radiotherapy, heterogenous alternatives (ranging from vigilance to adjuvant Rituximab monotherapy or immunochemotherapy) are used as evident from prospective observational studies and real-world series [21]. The combination of radiotherapy with systemic treatments (chemotherapy or immunochemotherapy) has been shown to prolong PFS but not OS, and the decision to offer additional treatment remains both patient and physician dependent [22][23]. These concepts have been applied to early PSFL. On the other hand, PSFL presenting with combinations of liver, bone marrow and peripheral blood involvement are expected to behave like advanced FL (stage IV), and the therapeutic choices range from active observation (for low tumor burden asymptomatic disease) to first line immunochemotherapy (for high tumor burden symptomatic disease) [17]. Commonly, combinations of Rituximab with Bendamustine, CHOP or CVP have been used as first line regimens [24][25]. Recently, substituting Rituximab for Obinutuzumab (a type II glycoengineered humanized anti-CD20 monoclonal antibody) in similar chemotherapy combinations was shown to prolong PFS without impacting OS [26].
Maintenance regimens with anti-CD20 monoclonal antibodies have been applied by several investigators, again prolonging PFS but not OS [27]. The efficacy of maintenance regimens for advanced leukemic disease (as is common in stage IV PSFL) deserves investigation, since lymphocytosis at presentation implies poor prognosis in nodal FL [28][29]. Treatment of relapsed PSFL can also be modelled on nodal FL, where management is influenced by multiple, patient and disease related factors, including the interval between diagnosis and relapse, and documentation of histologic transformation. A growing number of signaling pathway-specific/non-chemotherapy agents and cellular therapies are becoming available for FL, which could change the course of this still incurable disease [30][31]. However, the applicability of these new strategies to PSFL is unknown, and probably dependent on further clarification of specific biological characteristics and pathogenic mechanisms.
Conclusive data on prognostication of PSFL are not available yet. In the largest series published to date, survival was similar to nodal FL using treatment options ranging splenectomy alone to combined surgery and chemotherapy [13]. It is conceivable that the prognosis of PSFL may be influenced by the stage of disease and prognostic scores usually applied to nodal FL (namely the Follicular Lymphoma International Prognostic Index/FLIPI and FLIP2) [32][33]. However, the clinical outcomes of patients with spleen-confined disease have been similar to those of individuals with disseminated lymphoma [7], which may be explained by a limited sample size.
When PFSL transforms to aggressive lymphoma, regimens for DLBCL (immunochemotherapy with anti-CD20 antibodies and standard anthracycline-based chemotherapy for at least four cycles in localized stages) are used achieving comparable results.
This entry is adapted from 10.3390/curroncol28060407
Gobbi, P.G.; Grignani, G.E.; Pozzetti, U.; Bertoloni, D.; Pieresca, C.; Montagna, G.; Ascari, E. Primary splenic lymphoma: Does it exist? Haematologica 1994, 79, 286–293.
Healy, N.A.; Conneely, J.B.; Mahon, S.; O'Riardon, C.; McAnena, O.J. Primary splenic lymphoma presenting with ascites. Rare Tumors 2011, 3, 81–82.
Shimizu-Kohno, K.; Kimura, Y.; Kiyasu, J.; Miyoshi, H.; Yoshida, M.; Ichikawa, R.; Niino, D.; Ohshima, K. Malignant lymphoma of the spleen in Japan: A clinicopathological analysis of 115 cases. Pathol. Int. 2012, 62, 577–582.
Özsan, N.; Bedke, B.J.; Law, M.E.; Inwards, D.J.; Ketterling, R.P.; Knudson, R.A.; Keeney, G.L.; Dogan, A.; Feldman, A.L. Clinicopathologic and genetic characterization of follicular lymphomas presenting in the ovary reveals 2 distinct subgroups. Am. J. Surg. Pathol. 2011, 35, 1691–1699.
Vang, R.; Medeiros, L.J.; Ha, C.S.; Deavers, M.T. Non-Hodgkin's lymphomas involving the uterus: A clinicopathologic analysis of 26 cases. Mod. Pathol. 2000, 13, 19–28.
Swerdlow, S.H.; Campo, E.; Harris, N.L.; Jaffe, E.S.; Pileri, S.A.; Stein, H.; Thiele, J. (Eds.) WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues, Revised, 4th ed.; IARC: Lyon, France, 2017.
Howard, M.T.; Dufresne, S.; Swerdlow, S.H.; Cook, J.R. Follicular lymphoma of the spleen: Multiparameter analysis of 16 cases. Am. J. Clin. Pathol. 2009, 131, 656–662.
Shimono, J.; Miyoshi, H.; Kamimura, T.; Eto, T.; Miyagishima, T.; Sasaki, Y.; Kurita, D.; Kawamoto, K.; Nagafuji, K.; Seto, M.; et al. Clinicopathological features of primary splenic follicular lymphoma. Ann. Hematol. 2017, 96, 2063–2070.
Jhuang, J.Y.; Hsieh, Y.C.; Kuo, C.C.; Su, Y.Z.; Chuang, S.S. Primary splenic low-grade follicular lymphoma presenting with leukaemia and large cell transformation in the marrow. Pathology 2017, 49, 649–652, Erratum in 2017, 49, 819.
Jasionowski, T.M.; Hartung, L.; Greenwood, J.H.; Perkins, S.L.; Bahler, D.W. Analysis of CD10+ hairy cell leukemia. Am. J. Clin. Pathol. 2003, 120, 228–235.
Le, M.; Ghazawi, F.; Alakel, A.; Netchiporouk, E.; Rahme, E.; Zubarev, A.; Powell, M.; Moreau, L.; Roshdy, O.; Glassman, S.J.; et al. Incidence and Mortality Trends and Geographic Patterns of Follicular Lymphoma in Canada. Curr. Oncol. 2019, 26, 473–481.
Junlén, H.R.; Peterson, S.E.; Kimby, E.; Lockmer, S.; Linden, O.; Nilssonehle, H.; Erlanson, M.; Hagberg, H.; Rådlund, A.; Hagberg, O.; et al. Follicular lymphoma in Sweden: Nationwide improved survival in the rituximab era, particularly in elderly women: A Swedish Lymphoma Registry study. Leukemia 2015, 29, 668–676.
Mollejo, M.; Rodríguez-Pinilla, M.S.; Montes-Moreno, S.; Algara, P.; Dogan, A.; Cigudosa, J.C.; Juarez, R.; Flores, T.; Forteza, J.; Arribas, A.; et al. Splenic follicular lymphoma: Clinicopathologic characteristics of a series of 32 cases. Am. J. Surg. Pathol. 2009, 33, 730–738.
Fallah, J.; Olszewski, A.J. Diagnostic and therapeutic splenectomy for splenic lymphomas: Analysis of the National Cancer Data Base. Hematology 2019, 24, 378–386.
Matsuda, I.; Okada, M.; Inoue, T.; Tokugawa, T.; Ogawa, H.; Hirota, S. Primary follicular lymphoma of the spleen incidentally found in a patient with alcohol- and hepatitis C-related liver cirrhosis. Int. J. Clin. Exp. Pathol. 2014, 7, 4484–4488.
Dayama, A.P.; Kapoor, R.; Dass, J.; Singh, G.; Mahapatra, M.; Pati, H. Pathologic splenic rupture in a patient with follicular lymphoma. Mediterr. J. Hematol. Infect. Dis. 2011, 3, e2011051.
Dreyling, M.; Ghielmini, M.; Rule, S.; Salles, G.; Ladetto, M.; Tonino, S.; Herfarth, K.; Seymour, J.; Jerkeman, M. Newly diagnosed and relapsed follicular lymphoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann. Oncol. 2021, 32, 298–308.
Maciocia, N.; O'Brien, A.; Ardeshna, K. Remission of Follicular Lymphoma after Treatment for Hepatitis C Virus Infection. N. Engl. J. Med. 2016, 375, 1699–1701.
Arcaini, L.; Besson, C.; Frigeni, M.; Fontaine, H.; Goldaniga, M.; Casato, M.; Visentini, M.; Torres, H.A.; Loustaud-Ratti, V.; Peveling-Oberhag, J.; et al. Interferon-free antiviral treatment in B-cell lymphoproliferative disorders associated with hepatitis C virus infection. Blood 2016, 128, 2527–2532.
Alric, L.; Besson, C.; Lapidus, N.; Jeannel, J.; Michot, J.-M.; Cacoub, P.; Canioni, D.; Pol, S.; Davi, F.; Rabiega, P.; et al. Antiviral Treatment of HCV-Infected Patients with B-Cell Non-Hodgkin Lymphoma: ANRS HC-13 Lympho-C Study. PLoS ONE 2016, 11, e0162965.
Friedberg, J.W.; Taylor, M.D.; Cerhan, J.; Flowers, C.R.; Dillon, H.; Farber, C.M.; Rogers, E.S.; Hainsworth, J.D.; Wong, E.K.; Vose, J.M.; et al. Follicular lymphoma in the United States: First report of the national lymphocare study. J. Clin. Oncol. 2009, 27, 1202–1208.
MacManus, M.; Fisher, R.; Roos, D.; O'Brien, P.; Macann, A.; Davis, S.; Tsang, R.; Christie, D.; McClure, B.; Joseph, D.; et al. Randomized Trial of Systemic Therapy after Involved-Field Radiotherapy in Patients with early-Stage Follicular Lymphoma: TROG 99.03. J. Clin. Oncol. 2018, 36, 2918–2925.
Advani, R.; Rosenberg, S.A.; Horning, S.J. Stage I and II follicular non-Hodgkin's lymphoma: Long-term follow-up of no initial therapy. J. Clin. Oncol. 2004, 22, 1454–1459.
Marcus, R.; Imrie, K.; Solal-Celigny, P.; Catalano, J.V.; Dmoszynska, A.; Raposo, J.C.; Offner, F.C.; Gomez-Codina, J.; Belch, A.; Cunningham, D.; et al. Phase III study of R-CVP compared with cyclophosphamide, vincristine, and prednisone alone in patients with previously untreated advanced follicular lymphoma. J. Clin. Oncol. 2008, 26, 4579–4586.
Hiddemann, W.; Kneba, M.; Dreyling, M.; Schmitz, N.; Lengfelder, E.; Schmits, R.; Reiser, M.; Metzner, B.; Harder, H.; Hegewisch-Becker, S.; et al. Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma compared with therapy with CHOP alone: Results of a prospective randomized study of the German Low-Grade Lymphoma Study Group. Blood 2005, 106, 3725–3732.
Marcus, R.; Davies, A.; Ando, K.; Klapper, W.; Opat, S.; Owen, C.; Phillips, E.; Sangha, R.; Schlag, R.; Seymour, J.F.; et al. Obinutuzumab for the First-Line Treatment of Follicular Lymphoma. N. Engl. J. Med. 2017, 377, 1331–1344.
Salles, G.A.; Seymour, J.F.; Feugier, P.; Offner, F.; Lopez-Guillermo, A.; Belada, D.; Xerri, L.; Bouabdallah, R.; Catalano, J.; Brice, P.; et al. Long term follow-up of the PRIMA study: Half of patients receiving rituximab maintenance remain progression free at 10 years. Blood 2017, 130 (Suppl. S1), 486.
Sarkozy, C.; Baseggio, L.; Feugier, P.; Callet-Bauchu, E.; Karlin, L.; Seymour, J.F.; Lebras, L.; Michallet, A.-S.; Offner, F.; Dumas, O.; et al. Peripheral blood involvement in patients with follicular lymphoma: A rare disease manifestation associated with poor prognosis. Br. J. Haematol. 2013, 164, 659–667.
Sarkozy, C.; Seymour, J.F.; Ferme, C.; Caballero, L.; Ghesquieres, H.; Leppä, S.; Delarue, R.; Pedersen, L.M.; Mounier, C.; da Silva, M.G.; et al. Rituximab maintenance obviates the poor prognosis associated with circulating lymphoma cells in patients with follicular lymphoma. Blood 2014, 123, 2740–2742.
Apostolidis, J.; Mokhtar, N.; Al Omari, R.; Darweesh, M.; Al Hashmi, H. Follicular lymphoma: Update on management and emerging therapies at the dawn of the new decade. Hematol. Oncol. 2020, 38, 213–222.
Matasar, M.J.; Luminari, S.; Barr, P.M.; Barta, S.K.; Danilov, A.V.; Hill, B.T.; Phillips, T.J.; Jerkeman, M.; Magagnoli, M.; Nastoupil, L.J.; et al. Follicular lymphoma: Recent and emerging therapies, treatment strategies, and remaining unmet needs. Oncologist 2019, 24, e1236–e1250.
Solal-Céligny, P.; Roy, P.; Colombat, P.; White, J.; Armitage, J.O.; Arranz-Saez, R.; Au, W.Y.; Bellei, M.; Brice, P.; Caballero, D.; et al. Follicular lymphoma international prognostic index. Blood 2004, 104, 1258–1265.
Federico, M.; Bellei, M.; Marcheselli, L.; Luminari, S.; Lopez-Guillermo, A.; Vitolo, U.; Pro, B.; Pileri, S.; Pulsoni, A.; Soubeyran, P.; et al. Follicular lymphoma international prognostic index 2: A new prognostic index for follicular lymphoma developed by the international follicular lymphoma prognostic factor project. J. Clin. Oncol. 2009, 27, 4555–4562.


Key question are: Where are the latest opportunities and priorities for new investments and partnerships within African TMT sectors? Where is it worth investing? What are the key drivers in each sub-segment? Who are the investors? Where are the pitfalls and challenges by TMT segments? Who are the investors?
5 analysts and writers produced this report between 2014 and the end of March 2016.


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China's Anti-Poverty Efforts: Problems and Progress
Fatoumata Diallo
Focus Asia	March, 2019, pp. 4
China's poverty alleviation efforts have enjoyed political support from the highest levels of government since the Deng Xiaoping era. It is little surprise, therefore, that Xi Jinping has continued to treat them as a policy priority during his second term in office.
President Xi has identified anti-poverty as one of three "tough battles" for 2017 to 2020 (the other two being, risk prevention and pollution control). Beijing has set the agenda for government institutions at all levels to lift another 10 million Chinese citizens out of poverty in rural areas in 2019, an objective in line with the President's pledge of a moderately prosperous society by 2020. With the deadline fast approaching, Beijing is beginning to feel the pressure and is ramping up its efforts. Progress of China's poverty alleviation campaign is noteworthy, although problems still loom ahead.
A Measured Success
From Beijing's perspective, the "largest poverty alleviation campaign in history" has been an overall success. The campaign has revolved around the development of local industries, education, healthcare and combating corruption and abuses in poverty alleviation itself. It has lifted more than 68 million people living in China's rural areas out of poverty over the past five years. In other words, 37,000 Chinese were able to escape poverty every day, driving the national poverty rate down from 10.2 to 3.1 percent. The importance given to the role of the Party and government has implications for both the possibilities and stumbling blocks of China's anti-poverty drive, especially when set against the efforts of the political leadership to reform Chinese society.
From the vantage point of the international community, these policy efforts have significantly contributed to the decline in global poverty and have the potential to serve as imitable lessons for others. This begs the question of how Chinese insights can be used for cooperative programs around the world, and whether Beijing's domestic approaches can be replicable in an international setting.
This year marks the 40th anniversary of the reform and opening-up, which is credited with the elevation of 730 million Chinese people out of poverty, accounting for over 70 percent of global poverty reduction accomplishments over four decades. To achieve the target for 2020, Beijing will need to raise in excess of 10 million people out of poverty every year or put differently nearly one million people per month or 20 people per minute. The importance of this target may in part be attributed to Xi's experience of exile to a poverty-stricken rural village during the Cultural Revolution. It is possible that his exposure to conditions in poverty-stricken farming communities grafted itself onto his political consciousness during this formative period.
All things related to domestic policy in China are subject to massive numbers, and rural development is no exception. In 2016, a staggering 775,000 officials were dispatched to the countryside where they took up the job of relieving conditions in impoverished areas in one to three-year posts. Many of these are drawn specifically from the Organization Department of the Central Committee of the CPC, serving to imbed the party in the grass roots drive to reshape China's agrarian communities. Some have argued that the involvement of the CPC's Central Committee reflects the political importance given to these policies and has driven the rapid decrease in poverty figures.
In order to achieve the objectives set by the 2016-2020 poverty alleviation plan, the Chinese government has considerably ramped up financial support, allocating 91 billion RMB (13 billion USD) of poverty alleviation funds for 2019. The Chinese Development Bank has pledged 400 billion RMB to fund poverty alleviation projects (51 billion euros). To complement this, President Xi has called for stricter oversight of poverty alleviation funds management. This includes the implementation of regular inspections of local Party organizations involved in poverty alleviation work in order to prevent graft or misuse of funds. In the past five years, more than 60,000 cases of corruption and misconduct in poverty relief efforts have been reported. Last year alone, China's supreme anti-graft agency, the Central Commission for Discipline Inspection CCDI announced it had recouped 730 million (112.20 USD) in misappropriated poverty alleviation funds. The investigations revealed violations including bribery, fraud, falsification and funds embezzlement.
The government has also considerably ramped up financial support, allocating 91 billion RMB (ca. 13 billion USD) to poverty alleviation funds for 2019. The Chinese Development Bank has pledged 400 billion RMB to fund poverty alleviation projects (51 billion Euros). Where there are large sums of money there is also graft, and the state has taken pains to suppress funding hemorrhages. According to the "Central Commission for Discipline Inspection", 388 people received administrative or criminal penalties for embezzling anti-poverty funds. Many more have been looked into, some sources indicate as many as 1,800 officials have come under investigation, although such figures can be difficult to independently verify.
Alongside Indonesia, China has contributed to falling rates of extreme poverty from nearly half of the world's population in 1990 to just 9.3 percent in 2013. The UN Millennium Development Goals Report 2015 indicates that Chinese citizens play an outsized role in the figures of poverty reduction, and Beijing's policies have greatly contributed to the meeting of the UN millennium goal to halve extreme poverty globally.
Targeted Poverty Alleviation
One of the central pillars of the poverty alleviation efforts under Xi's leadership has been the strategy of targeted poverty alleviation. The President first put forward the notion in 2013 during an inspection tour in the Hunan province. The approach calls for the implementation of tailored sets of measures targeting households and individuals rather than whole villages or counties. For that purpose, China has created a national registration system for poor households that enables local officials to gather data from each individual person, household and village. The system, which registered data for 128,000 villages and 290,000 households, has helped to identify the most poverty-stricken areas, including in the Guizhou Hunan, Guangxi, Sichuan and Yunnan provinces.
President Xi has also stressed that this targeted poverty alleviation strategy should follow a five-batch policy – based on industrial development, relocation, eco-compensation, education and social security – and establish seven institutional systems (registration, policy, investment, assistance, social mobilization, multi-channel, all-around supervision, and assessment system). The pairing up strategy – which allows impoverished provinces in the west of the country to receive assistance from more developed provinces in the east – has been extended to cover 30 provinces including ethnic minorities areas. Impoverished households have been assigned officials dispatching to the countryside, which again reflects the massive amounts of manpower being devoted to the campaign and the hands-on approach being played by the party.
The government has also accelerated the development of "Internet Plus" strategies in the fight against poverty. For instance, Chinese internet giant Alibaba has supported the creation of rural e-commerce centers known as Taobao villages that encourage online sales of farm produce and local specialties. By 2015, 780 Taobao villages in China catered to over 200,000 active online shop owners and collectively employed over one million people. Galvanized by this success Alibaba nominated a further 2,100 Taobao villages to take part in the program in 2017.
A further component of the grand architecture of the anti-poverty policy is the rural resettlement program. Deemed a key strategy in the fight against poverty, it encourages the relocation of elements of the rural population who live in remote or ecologically fragile regions to areas closer to the cities. It is expected that 9.81 million people will be moved between 2016 and 2020 as part of this program.
Sharing Development with Chinese Characteristics
In consideration of its substantial achievements in the field of poverty alleviation, Beijing has touted the "Chinese approach" as a suitable model for other countries struggling with widespread poverty. This is all the more pressing given the Chinese leadership's very public and very substantial support for the Belt and Road Initiative, which touches upon any areas in which poverty is a very real social and political force. In particular, the government has encouraged experience and knowledge exercises intended to facilitate poverty alleviation by creating cooperation programs with African countries. Such activities include the organization of workshops, training sessions, forums and conferences. Delegations from African countries have been invited to visit some of China's most under-developed regions in order to learn about targeted poverty alleviation methods first hand. Other countries in China's orbit already appear to have adopted China's poverty alleviation model. Recently, Pakistan's Prime Minister Imran Khan, praised the Chinese experience as a "role model" for his country.
In May 2018, the Chinese government launched a Global Poverty Reduction & Inclusive Growth Platform to share the country's lessons and best practices. However, it will remain to be seen whether other countries will be able to replicate Chinese successes or whether leaders like Imran Khan, who are in need of financial assistance, are merely paying lip service to the narrative of Chinese success.
Challenges Ahead
Another lingering question is whether the goals set for 2020 are attainable. There is still a major need to improve the allocation and management of funds. Local governments have approval power over the allocation of financial aid but their decisions can often be arbitrary. As a result, some poor households end up being denied financial help while others with more resources receive greater subsidies. In some areas, overly strict bureaucratic practices impede poverty alleviation efforts. Furthermore, even households which receive subsidies end up accumulating growing debt to cover medical costs – which for the most part is not covered by the government.
The relocation scheme has raised controversy because relocated residents are forced to abandon their lands in exchange for relatively scarce compensation. Several end up moving back to their home villages because they are unable to find work in the city or cannot afford the high cost of living. Furthermore, while the government is encouraging a sort of rural exodus as part of its relocation program, it is paradoxically cracking down on poor migrant workers in the big cities such as Beijing or Shanghai.
Regardless, for those who have first-hand experience of the transformative power of China's poverty alleviation campaign, the notion that Beijing's policy may have a major and intimate impact on individual lives is very real.
Xiong'an: A New Model of Digital Chinese Urbanism?
Ms. Fatoumata Diallo gives her views on Xi Jinping's plans to create a new innovative development zone in the city of Hebei. Is this project intended to project China as […]
Focus Asia	December, 2018, pp. 4
Mahathir: Uighurs "have done nothing wrong"
Elliot Brennan
Horror stories have trickled out of China's Xinjiang province for years. Now research points to a flood of human suffering and disturbing human rights abuses. Yet with threats of China's economic retribution, […]
Commentaries and Op-eds	October 18, 2018, The Interpreter
Made in China 2025
ISDP
Summary MIC 2025 is an initiative which strives to secure China's position a global powerhouse in high-tech industries. The aim is to reduce China's reliance on foreign technology imports and […]
Backgrounder	June, 2018, pp. 9
China's Role in UN Peacekeeping
Summary From the 1980s China has a more active foreign policy agenda and by the 1990s is contributing personnel to UN Peacekeeping missions. China is now the second largest contributor […]
Backgrounder	March, 2018, pp. 7

redpajama_set_name: RedPajamaCommonCrawl


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Denis Island is the second northeasternmost island in the Seychelles. It is  north of Mahé and lies at the northern edge of the Seychelles bank, along with the nearby Bird Island, which is the northernmost Seychelles island. The  coral island was named after the French Navy officer Denis de Trobriand, who explored it in 1773. Denis Island is privately owned and has a short airstrip. It has a holiday resort with 23 guest chalets.

A lighthouse built in 1910 still stands on the northern edge of the island. There is also a chapel named Chapel St. Denis.

The island has an abundance of coconut palms, Takamaka and Casuarina trees. In 2004, 47 Seychelles fodies from Fregate Island and 58 Seychelles warblers from Cousin Island were relocated to Denis as part of a Nature Seychelles conservation project.

The island has been designated a cay, in the Seychelles Archipelago.

See also
List of lighthouses in Seychelles

Gallery

References

External links
 IUCN Relocation Project
 Denis Island Resort
 Google Maps

Islands of La Digue and Inner Islands
Important Bird Areas of Seychelles
Lighthouses in Seychelles
Private islands of Seychelles

redpajama_set_name: RedPajamaWikipedia


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The following University of Utah alumni have been recognized by the Department of Atmospheric Sciences for their outstanding contributions and service to the Atmospheric Sciences profession. This list of distinguished alumni includes research scientists, professional meteorologists, veterans, and entrepreneurs. Please contact the Department of Atmospheric Sciences at atmos-office@lists.utah.edu if you would like to nominate yourself or someone else for the annual Distinguished Alumni Award. We invite our Distinguished Alumni Award winner to be the keynote speaker at our annual awards banquet, which is held the day before spring commencement.
Jennifer Comstock (2018)
Degree: Ph.D. (2000) Meteorology
Current Position: Engineering and Science Products Manager, Department of Energy Atmospheric Radiation Measurement (ARM) Program, Pacific Northwest National Laboratory
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Ping Yang (2017)
Current Position: Professor and Head of the Department of Atmospheric Sciences, Texas A & M University
Ethan Greene (2016)
Degree: B.S. (1997) Meteorology
Current Position: Director of the Colorado Avalanche Information Center (CAIC)
Steven A. Root (2015)
Degrees: B.S. (1976), M.S. (1980) Meteorology
Current Position: Chief Analytics Officer and Senior VP of Sales at AccuWeather, Inc.
John E. Jack Hales (2014)
Current Position: Lead Forecaster, Storm Prediction Center, National Weather Service, Norman, OK (Retired)
Kristi Gebhart (2013)
Current Position: Research Physical Scientist, Cooperative Institute for Research in the Atmosphere, Colorado State University
S. Edward Boselly (2012)
Degree: M.S. (1968) Meteorology
Current Position: Owner, Weather Solutions Group (Retired)
Jeffrey Anderson (2011)
Current Position: Senior Scientist Section Head, Data Assimilation Research Section, National Center for Atmospheric Research
Qiang Fu (2010)
Current Position: Professor, Department of Atmospheric Sciences, University of Washington
Dell Vaughn McDonald (2009)
Degree: B.S. (1960), M.S. (1966) Meteorology
Current Position: Lieutenant Colonel U.S. Air Force (Retired), President and CEO of Home Health Services, Inc. (Retired), Volunteer with the Road Home and the Housing Authority of Salt Lake County
Awards: 2016 Jack Gallivan Legacy Award Utah Housing Coalition
Patrick Minnis (2008)
Current Position: Senior Research Scientist, Science Directorate, NASA Langley Research Center
Kim (Waldron) Walsh (2007)
Degrees: M.S. (1991), Ph.D. (1994) Meteorology
Current Position: Colonel U.S. Air Force (Retired), Faculty National Defense University (Retired)
George Wilkerson (2006)
Current Position: Director Monitoring Services, Meteorological Solutions, Inc.
Vincent Salomonson (2005)
Current Position: Research Professor, Departments of Atmospheric Sciences and Geography, University of Utah
Larry Dunn (2004)
Degrees: B.S. (1979), Ph.D. (1993) Meteorology
Current Position: Meteorologist in Charge, National Weather Service, Salt Lake City Forecast Office (Retired)
Dan Pope (2003)
Current Position: Chief Meteorologist, ABC-4 TV, Salt Lake City, UT
William Alder (2002)
Current Position: Chief Information Officer at Sun Peak Capital, Salt Lake City, UT; Meteorologist in Charge, National Weather Service, Salt Lake City Forecast Office (Retired)
Fred Lewis (2002)
Current Position: Director of Policy and Resources, Office of
Information Dominance and Chief Information Officer, Office of the Secretary of the Air Force, Washington, D.C.
Awards: 2016 University of Utah Distinguished Alumni Award
Mark Eubank (2001)
Current Position: Chief Meteorologist, KSL-TV Channel 5, Salt Lake City, UT (Retired)
A. E. (Sandy) MacDonald (2001)
Current Position: Chief Science Advisor for NOAA's Office of Oceanic and Atmospheric Research, Director of the Earth System Research Laboratory, President of American Meteorological Society (2015)


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The structure of the Swiss militia system stipulates that the soldiers keep their own personal equipment, including all personally assigned weapons, at home (until 2007 this also included ammunition). Compulsory military service applies to all male Swiss citizens, with women serving voluntarily. Males usually receive initial orders at the age of 18 for military conscription eligibility screening. About two-thirds of young Swiss men are found suitable for service, while alternative service exists for those found unsuitable. Annually, approximately 20,000 persons are trained in basic trainingfor 18 weeks (23 weeks for special forces).


Former BYU tight end Dennis Pitta played in his first NFL game in nearly two years on Sunday, helping the Baltimore Ravens top the Buffalo Bills 13-7.
A pair of hip injuries have nearly derailed Pitta's career, but against the Bills, Pitta showed the chemistry he still has with Ravens quarterback Joe Flacco by catching three passes for 39 yards.
His biggest catch of the day came in the fourth quarter with the Ravens driving, looking to add to their lead. On a second-and-8 from midfield, Flacco dropped back and threaded a pass to Pitta down the middle for a 27-yard gain just beyond the reach of a defender.
That helped extend a 13-play drive that took 5:59 off the clock and ended with a Baltimore field goal that gave the Ravens a six-point lead.
For Pitta, who started the game for the Ravens, it was his first game in 721 days.
Devontae Booker, RB, Utah: Had three carries for 8 yards in six offensive snaps. Booker also lost a fumble on his first carry.
Tyler Larsen, G, Utah State and Jordan High: Not active for game.
Star Lotulelei, DT, Utah, Snow College and Bingham High: Started at left defensive end and had a pass deflection in 38 defensive snaps and three special teams snaps.
Jared Norris, LB, Utah: Not active for game.
Paul Soliai, DT, Utah: Played 19 defensive snaps.
Nate Orchard, OLB, Utah and Highland High: Had two quarterback hurries on 26 defensive snaps and seven special teams snaps.
Stephen Paea, DT, Snow College and Timpview High: Had one quarterback hurry on 16 defensive snaps.
Will Davis, SS, Utah State: Not active for game.
Dennis Pitta, TE, BYU: Story above.
Steve Smith Sr., WR, Utah: Smith started at wide receiver and had five receptions for 19 yards on nine targets for the Ravens. The 16th-year NFL veteran who put off retirement for one more year played 45 offensive snaps in the first game since coming back off a torn Achilles injury he suffered seven games into the 2015 season.
Eric Weddle, S, Utah: Started at strong safety and had four tackles, including three solo, and one pass deflection on 49 defensive snaps.
Tony Bergstrom, C, Utah and Skyline High: Played one offensive snap and five special teams snaps.
Xavier Su'a-Filo, OG, Timpview High: Started at left guard and played 75 offensive snaps and five special teams snaps.
Paul Lasike, RB/FB, BYU: In his first game on the 53-man active roster, Lasike started at fullback for the Bears to kick off his second NFL season. He played 14 offensive snaps and six special teams snaps.
Patrick Scales, LS, Utah State and Weber High: Played nine special teams snaps.
Marwin Evans, S, Utah State: Played six special teams snaps.
Kyler Fackrell, OLB, Utah State: Had one special teams tackle on seven defensive snaps and 18 special teams snaps.
Alex Smith, QB, Utah: Smith rallied his team from a 24-3 deficit in the third quarter. The Chiefs' starter completed 34-of-48 passes for 363 yards and two touchdowns with one interception for a 97.8 QB rating. He also carried the ball four times for 15 yards, including the game-winning 2-yard touchdown run in overtime. See story here.
Daniel Sorensen, DB, BYU: Had one quarterback hurry on 18 defensive snaps and 29 special teams snaps.
Tenny Palepoi, DT, Utah, Snow College and Skyline High: Played 19 defensive snaps and 21 special teams snaps.
Keith McGill, CB, Utah: McGill started at strong safety and had six tackles, including four solo. He added one pass deflection on 67 defensive snaps and 12 special teams snaps in the second start in his three-year career.
Donald Penn, T, Utah State: Started at left tackle and played 73 offensive snaps and four special teams snaps.
Sean Smith, CB, Utah: Started at right cornerback and had one tackle and a pass deflection on 43 defensive snaps.
Paul Kruger, OLB, Utah and Timpanogos High: Had one tackle on 39 defensive snaps and four special teams snaps.
Nick Vigil, ILB, Utah State and Fremont High: Had one special teams tackle on one defensive snap and 17 special teams snaps.
Derrick Shelby, DE, Utah: Started at defensive end and had three solo tackles on 32 defensive snaps and nine special teams snaps.
Matt Asiata, RB, Utah, Snow College and Hunter High: Had four carries for 13 yards on nine offensive snaps and 13 special teams snaps.
Brice McCain, CB, Utah: Had four tackles, including three solo and a special teams tackle, and one pass deflection on 33 defensive snaps and five special teams snaps.
LeShaun Sims, CB, Southern Utah: Not active for game.
Bobby Wagner, LB, Utah State: Wagner started at middle linebacker and had six solo tackles and a pair of quarterback hurries on 53 defensive snaps and three special teams snaps.
John Denney, LS, BYU: Played 10 special teams snaps.
Koa Misi, LB, Utah: Misi started at linebacker and had 10 tackles, including five solo, good enough for fourth on the Dolphins team. He played 69 defensive snaps and one on special teams.
Ezekiel Ansah, DE, BYU: Ansah started at defensive end and had two tackles, including one solo, as well as a tackle for loss and two quarterback hurries on 50 defensive snaps and three special teams snaps.
Miles Killebrew, SS, Southern Utah: Played two defensive snaps and 22 special teams snaps.
Nevin Lawson, CB, Utah State: Started at cornerback and had four tackles, including three solo, on 68 defensive snaps and five special teams snaps.
Haloti Ngata, DT, Highland High: Started at defensive tackle and had two tackles, including one solo, and a pass deflection on 45 defensive snaps and four special teams snaps.
Kyle Van Noy, LB, BYU: Started his first game at outside linebacker and had one pass deflection on 15 defensive snaps and 27 special teams snaps.
Robert Turbin, RB, Utah State: Had one carry for 4 yards and two receptions for 15 yards on 12 offensive snaps and 17 special teams snaps.
Eric Rowe, CB, Utah : Not active for game.
Alani Fua, ILB, BYU: Played 22 special teams snaps.
Zane Beadles, OL, Utah and Hillcrest High: Started at left guard and played 81 offensive snaps and four special teams snaps.
Maurice Alexander, S, Utah State: Alexander started at free safety and had three solo tackles and a pass deflection on 81 defensive snaps, one of five Rams defenders to play every defensive snap for Los Angeles. He also played five special teams snaps.
On Tuesday, the Raiders released outside linebacker Jason Fanaika (Utah and Pleasant Grove High) from their practice squad, while the Seahawks signed fullback Will Tukuafu (East High) to their 53-man roster and quarterback Jake Heaps (BYU) to their practice squad.
On Saturday, the Raiders reached an injury settlement with defensive end James Cowser (Southern Utah and Davis High), making him a free agent.
Also, NFL expert Aaron Wilson of the Houston Chronicle reported Tuesday that the Eagles worked out quarterback Brad Sorensen (Southern Utah) and wide receiver Jordan Leslie (BYU), among others.
UPDATE: Defensive back Tay Glover-Wright (Utah State) signed to the Colts' practice squad on Wednesday.
Total locals on rosters (as of Wednesday, Sept. 14): 58, 43 on active rosters, nine on practice squads, five on injured reserve and one on reserve/non-football injury list.


We take pride in our termite and pest control work and provide island-wide service. Some of the most fun we have is on our hardest jobs. It's those jobs where you can see the biggest difference and provide a more comfortable environment for families and pets.


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"I'm so aware of the responsibility I have to tell the story in the best way possible..." - hmv.com talks to the cast & director of Harriet
"I saw something there that could be very exciting and have people on the edge of their seats..." - hmv.com talks to Chadwick Boseman
"We really felt that we were missing a part of the story..." - hmv.com talks to the cast & directors of Frozen II
The Current War - Five Reasons You'll Love It
"I was completely astounded by what has been achieved, it's hard to get your head around..." hmv.com talks The Lion King with Chiwetel Ejiofor
Le Mans '66 - Five Reasons You'll Love It
"We couldn't just pull someone from the street, there's so much heavy lifting..." - The director and star of new horror Gwen open up
"It's a fork in the road for a lot of characters, especially Tommy ..." hmv.com talks to Peaky Blinders creator Steven Knight
"These films are going to branch out in a whole bunch of other ways..." - hmv.com talks to the cast of Spider-Man: Far From Home
"Actors want to work will Bill Condon, they've seen his movies..." - hmv.com talks to the cast and director of The Good Liar


There will be special guests: prominent scientists will discuss future research and technology; office holders, candidates and advocates of public policy will discuss impending elections and critical political issues; famous actors, directors, musicians and athletes will preview coming events in sports and entertainment.
· The audience will have the opportunity to participate in live Q & A sessions.
Before and after the show, the audience will have the opportunity to view live and interactive industrial presentations of products and services in development for the future. These sponsored presentations will be selected for their importance, compelling content, and entertaining presentation.
The program will be available as an interactive presentation on CD-ROM and DVD.
Computer based products for prediction and planning will be created based on the methodologies described in the show.
A free web site will provide enriched information, including links to the industrial presentations in the show, and BLOGs -- such as QPORIT -- Quick PREVIEWS Of Random Interesting Things, which is already live, plus other, special, topical BLOGs. The site will also promote the show and other future events. and feature online sales of ancillary products based on the show.
Other ancillary products which are planned include popular and technical books based on "How To Predict The Future" (and on related topics in forecasting for business and science), as well as a documentary film, and television shows previewing future events, including TV specials with predictions for each coming new year.
(c) Copyright 2004-2005 Eric H. Roffman - all rights reserved.


When you start to search for a new car insurance policy, you will soon realize that there are a multitude of companies in Alton, NH to choose from. Many people believe that they can only get good rates from well-known national companies, but there are actually many other businesses that do not do have a national advertising that can actually offer exceptional rates. Of course, you do need to verify the authenticity of each company that you find as they may not have the best overall rating. However, if you are able to use websites that can connect you with different companies that have already been verified, you simply need to choose one of them that will offer you the lowest price. Here are a few of the cheap car insurance online tips that you can use when searching for your coverage in New Hampshire, regardless of the type of vehicle that you drive or how much coverage you actually need.
Most people will start their research on the Internet, searching for individual car insurance providers, helping to get one that will offer them a much lower rate. There search could be prompted by an increase in their car insurance premiums from their existing company as a result of a claim that they filed recently. If this is the case, you can begin to get individual quotes from each of the businesses that you find to see which one can save you the most money. However, this could be a very time-consuming process, so the following discount car insurance rates tips will help you streamline your search for the best coverage the lowest possible price in Belknap county.
The following cheap car insurance online tips are probably ones that you have heard of before, but you may not have used. These strategies are not secret. They have been utilized by people for decades in order to get the best premiums on their auto insurance policies. The Internet has changed many things when it comes to finding cheaper rates for any type of insurance in Alton, New Hampshire that you may have. It gives you instant access to a multitude of companies that you may not have known about, businesses that can literally save you hundreds of dollars in premiums every month. The goal is to take your time and make sure that you are looking at every possible option. You can actually use multiple tips simultaneously. The goal is to do everything that you can to lower your premiums, especially if they have recently gone up, so that you can have more money to spend on yourself or your family.
These are just a few of the many strategies that you can use when you are looking for cheap car insurance online. Your best bet is to utilize online services that can submit your request for a quote to multiple companies, and use one of the many that send their quote to you. As mentioned earlier, some of these businesses may not advertise heavily so you may not have heard of them before. You can always verify the authenticity of an insurance company by checking the Better Business Bureau, and if they check out, this is a great way to save hundreds or thousands of dollars every year on your auto insurance premiums. Hopefully these cheapest automobile insurance online tips will lead you to the best possible insurance provider that can give you the best coverage at the lowest possible rates in Alton, NH.
Numerous sites offer you auto insurance policy details. You can actually get missing in a sea of them if you are not careful. Sorting through it all to locate details that is relevant to you may possibly not be fun, or rapidly. Fortunately, you will uncover almost everything you require to know proper right here. Read through on for far more.
Currently being a mindful driver can genuinely preserve you money on insurance coverage. Certainly, insurers would rather insure good motorists and will give reduce rates for excellent drivers, but did you know that triggering an accident can make your insurance policy rates almost double? It is abundantly distinct that driving safely and securely is one particular of the greatest techniques to preserve your insurance coverage costs reduced!
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Biotransformation and detectability of the new psychoactive substances N,N-diallyltryptamine (DALT) derivatives 5-fluoro-DALT, 7-methyl-DALT, and 5,6-methylenedioxy-DALT in urine using GC-MS, LC-MSn, and LC-HR-MS/MS
Michely, JA, Brandt, SD, Meyer, MR and Maurer, HH (2017) Biotransformation and detectability of the new psychoactive substances N,N-diallyltryptamine (DALT) derivatives 5-fluoro-DALT, 7-methyl-DALT, and 5,6-methylenedioxy-DALT in urine using GC-MS, LC-MSn, and LC-HR-MS/MS. Analytical and Bioanalytical Chemistry, 409 (6). pp. 1681-1695. ISSN 1618-2642
ABC_5F_7Me_5,6MD-DALT_accepted.pdf - Accepted Version
Publisher URL: http://dx.doi.org/10.1007/s00216-016-0117-5
Derivatives of N,N-diallyltryptamine (DALT) can be classified as new psychoactive substances. Biotransformation and detectability of 5-fluoro-DALT (5-F-DALT), 7-methyl-DALT (7-Me-DALT), and 5,6-methylenedioxy-DALT (5,6-MD-DALT) are described here. Their metabolites detected in rat urine and pooled human liver microsomes were identified by liquid chromatography (LC)-high resolution (HR)-tandem mass spectrometry (MS/MS). In addition, the human cytochrome-P450 (CYP) isoenzymes involved in the main metabolic steps were identified and detectability tested in urine by the authors' urine screening approaches using GC-MS, LC-MSn, or LC-HR-MS/MS. Aromatic and aliphatic hydroxylations, N-dealkylation, N-oxidation, and combinations could be proposed for all compounds as main pathways. Carboxylation after initial hydroxylation of the methyl group could also be detected for 7-Me-DALT and O-demethylenation was observed for 5,6-MD-DALT. All phase I metabolites were extensively glucuronidated or sulfated. Initial phase I reactions were catalyzed by CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, and CYP3A5. Rat urine samples were analyzed following two different low dose administrations. GC-MS was not able to monitor consumption reliably, but all three drugs are predicted to be detectable in cases of overdose. The LC-MSn and LC-HR-MS/MS approaches were suitable for detect an intake of all three compounds mainly via their metabolites. However, after the lowest dose, a reliable monitoring could only be achieved for 5-F-DALT via LC-MSn and LC-HR-MS/MS and for 7-Me-DALT via LC-HR-MS/MS. The most abundant targets in both LC-MS screenings were one of two hydroxy-aryl metabolites and both corresponding glucuronides for 5-F-DALT, one N-deallyl hydroxy-aryl, the carboxy, and one dihydroxy-aryl metabolite for 7-Me-DALT, and the demethylenyl metabolite, its oxo metabolite, and glucuronide for 5,6-MD-DALT.
The final publication is available at Springer via http://dx.doi.org/10.1007/s00216-016-0117-5
03 Chemical Sciences, 06 Biological Sciences, 09 Engineering
Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
Pharmacy & Biomolecular Sciences


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Salmonella Outbreak Linked to Frozen Cooked Shrimp Distributed by Avanti Frozen Foods
If you have been affected by this outbreak, please get in touch with us for a free consultation.
by phone or email
EM: advice@oftlaw.com
Or Text Us
or by using our online form
Outbreak Summary
A multistate outbreak of Salmonella Weltevreden illnesses has been traced back to various sizes of frozen cooked, peeled, deveined, shrimp sold by Avanti Frozen Foods. A recall has been issued for products sold under a variety of brand names, including: Censea, Hannaford, Open Acres, Waterfront Bistro, Honest Catch, Chicken of the Sea, 365, and Meijer.
At least 9 people were sickened in this outbreak, with 3 of them hospitalized. The known illnesses were spread across the country in Arizona, Michigan, Nevada, and Rhode Island.
On July 21, 2021, the CDC declared this outbreak to be over. But on August 16th, an expanded recall was issued after additional illnesses were reported, some of which involved products not subject to the initial recall. Thus, OFT's Salmonella lawyers are still actively investigating this outbreak, and this page will update as we uncover more information. If you or a loved believe you were sickened in this outbreak, please call or contact us using the form on the page for a free consultation.
Signs of Food Poisoning & Contamination
Hot and cold flashes
If you're experiencing signs of food poisoning, contact us today.
EM | advice@oftlaw.com
At least 9 people in 3 states have been sickened in an outbreak of Salmonella Weltevreden linked to frozen cooked shrimp products distributed by Avanti Frozen Foods. Illnesses linked to the products have been reported in Arizona, Michigan, Nevada and Rhode Island:
A recall has been issued for dozens of products containing the frozen shrimp. A full list is available here. Several sushi products containing shrimp sourced from Avanti have also been recalled: sushi containing cocktail shrimp by Genji Pacific LLC, Shrimp Tempura Kabuki Roll by Mai Cuisine Inc., and sushi containing cocktail shrimp by Mai Franchising Inc. Given that the product is frozen shrimp, consumers are advised to check their freezers to make sure that they do not possess the tainted products.
Salmonella Weltevreden
There are more than 2,500 serotypes of Salmonella, but fewer than 100 cause infections in humans. One of these illness-causes strains is a serotype called Weltevreden, and it is responsible for the current outbreak. Salmonella poisoning can be so severe that it requires people to be hospitalized. Indeed, two people sickened in this outbreak so far have been hospitalized.
Salmonella can even be fatal when the infection leaves the intestines and travels to the bloodstream or other parts of the body. It is also possible to experience long-term side effects, including joint pain known as reactive arthritis, which is also known as Reiter's Syndrome. This can last for months or years and result in chronic arthritis, which is difficult to treat. Reactive arthritis can also lead to eye irritation and painful urination. In rare cases, some types of Salmonella cause typhoid fever, which can be fatal.
OFT Food Safety & Injury Lawyers Can Help
OFT Food Safety & Injury Lawyers was built to get the answers you need and the results you deserve. We have recovered millions for our clients and have forced the food industry to become safer for all of us.
Our Salmonella lawyers are renowned within the food safety industry, believe in the cases we take, and have the courtroom experience to get results. We handle food injury cases nationwide and are ready to put our knowledge, experience, and resources behind your case.
OFT Food Safety & Injury Lawyers is a national law firm that focuses on food safety and protection of those who have been infected. We have experience with all types of outbreaks, including Salmonella. We offer free consultations to anybody potentially impacted by a food poisoning outbreak, and will offer honest advice about whether it makes sense to file a Salmonella lawsuit.
Notable Recoveries
Seven infants were sickened after consuming a contaminated food product marketed to infants
Verdict on behalf of a little boy who contracted a severe Salmonella infection from chicken
$7.55 million
Verdict on behalf of a little girl who contracted E. coli at a petting zoo
E. coli infections contracted from a major fast food chain
An over-the-counter medication caused severe kidney damage to multiple users
A pregnant woman contracted a Listeria infection from contaminated fruit and passed the infection to her child
Multistate Cyclospora outbreaks
A couple contracted Salmonella from a restaurant
A pedestrian was struck by a left-turning car, fracturing her tibia
A semi-truck rear-ended a motorcyclist causing a collapsed lung, rib fractures and road rash
We handle food poisoning cases nationwide, offer 100% free consultations. There are no fees unless you recover compensation.
EM advice@oftlaw.com
OFT Food Safety & Injury Lawyers
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The material on this website is for informational purposes only and is not intended to create an attorney-client relationship. Please do not send any confidential information until an attorney-client relationship has been established.


New York , 10024. The USPTO has given the MULTI-PHARM trademark serial number of 74259321.
MULTI-PHARM sells goods and services of medical devices; namely, pill dispensers. This logo and TradeMark was filed on March 26, 1992 and was first used on January 01, 1970.


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I was asked to pray naked for Tinubu's victory – Olaiya Igwe
Veteran actor Olaiya Igwe has revealed why he went nude to pray for the presidential candidate of the All Progressives Congress (APC) Bola Tinubu at a beacA video of the naked actor praying for Tinubu's victory which went viral on Saturday attracted mixed reactions with many people knocking the him for his action.
However, in an interview with media personality Morayo Afolabi-Brown on Your View breakfast show aired on TVC on Monday, Olaiya Igwe claimed he was given a spiritual mandate to carry out the act to ensure Tinubu's victory.
He said: "I will go straight to what I did last four days ago. I was asked to stand up and do it spiritually. I have a gift of revelation by Almighty God. At times I see what God plans for me ahead before it happens. I was sleeping that day and the voice came to me and said 'please stand up, you said you love Asiwaju and he has been assisting you', I said 'yes'. He said stand up go and do this and this for him."
Earlier in August, Olaiya, who began his acting career after joining Abeokuta-based Musbau Shodimu Theatre Organisation, trended on social media when he posted a clip of himself prostrating before his benefactor and staunch supporter of Tinubu, MC Oluomo after he was gifted a brand new car by the latter.
Blaqbonez expresses disappointment over Wizkid's criticism of rap
Family releases funeral arrangements for late gospel singer, Sammie Okposo


The Well Group Online Store (www.wellgroup.com.hk) is operated & totally owned by "Well Group Global Limited".
Well Group Global Limited is a Hong Kong based company and a manufacturer of cookie cutters, bakeware and tart moulds. In addition, we represent many factories in China that offer different OEM products for export. Our export merchandisers can offer you and your company a very competitive price, good quality products and the best service. To add to the fun and enjoyment of the festivals, we have put together different sets of gift items using our home décor products and unique designed home textiles for different occasions like Christmas and Valentine's Day. These gift items are also perfect for brand promotion and advertisement. Please refer to our website for our full range of products.
Well Group Global Limited is also the sole distributor of Progressive International Corporation products in Hong Kong and Macau. Progressive International Corporation operates from a 235,000 sq. ft. facility in a commercial park approximately 20 miles from downtown Seattle, Washington, USA . The company was founded in 1973 selling only steamer baskets and today, its products include a broad selection of quality kitchenware, kitchen tools, cookware and bakeware. The products are distributed throughout different channels to North America, Europe, Australia, South Africa and recently added to the list, Japan. Asia is a new area that the company wants to focus on and Hong Kong is logically the first place to be.


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Q: Excluding .class files from Gradle dependency I'm trying to import https://github.com/Kickflip/kickflip-android-sdk using gradle into my android build and I'm getting :

UNEXPECTED TOP-LEVEL EXCEPTION:
      com.android.dex.DexException: Multiple dex files define Lorg/apache/commons/codec/binary/Base64;

Commons.codec is a dependency of my project, but not directly of the kick-flip project, I think its coming from one of the jars included there. I can see the .class files if I open Kickflip's classes.jar.
How can I exclude Base64.class from being imported from kickflip into the final build? I've looked at using ziptree to exclude things but haven't been able to get anything to work.
Thanks
My build.gradle is:
apply plugin: 'android'

android {
    compileSdkVersion 19
    buildToolsVersion "19.0.3"

    defaultConfig {
        minSdkVersion 10
        targetSdkVersion 19
        versionCode 1
        versionName "1.0"
    }
    buildTypes {
        release {
            runProguard false
            proguardFiles getDefaultProguardFile('proguard-android.txt'), 'proguard-rules.txt'
        }
    }

    compileOptions {
        sourceCompatibility JavaVersion.VERSION_1_7
        targetCompatibility JavaVersion.VERSION_1_7
    }

    packagingOptions {
        exclude 'META-INF/DEPENDENCIES.txt'
        exclude 'META-INF/LICENSE.txt'
        exclude 'META-INF/NOTICE.txt'
        exclude 'META-INF/NOTICE'
        exclude 'META-INF/LICENSE'
        exclude 'META-INF/DEPENDENCIES'
        exclude 'META-INF/notice.txt'
        exclude 'META-INF/license.txt'
        exclude 'META-INF/dependencies.txt'
        exclude 'META-INF/LGPL2.1'
        exclude 'META-INF/ASL2.0'
    }

    android.applicationVariants.all{ variant ->
        // This is an annoying hack to get around the fact that the Gradle plugin does not support
        // having libraries with different minSdkVersions. Play Services has a min version of 9 (Gingerbread)
        // but Android Maps Utils supports 8 (Froyo) still
        variant.processManifest.doFirst {
        File manifestFile = file("${buildDir}/exploded-aar/io.kickflip/sdk/0.9.9/AndroidManifest.xml")
            if (manifestFile.exists()) {
                println("Replacing minSdkVersion in Android Maps Utils")
                String content = manifestFile.getText('UTF-8')
                content = content.replaceAll(/minSdkVersion="18"/, 'minSdkVersion=\"10\"')
                manifestFile.write(content, 'UTF-8')
                println(content)
            }
        }
    }
}

dependencies {
    compile 'com.android.support:support-v4:19.1.0'
    compile 'io.kickflip:sdk:0.9.9'
    compile fileTree(dir: 'libs', include: '*.jar')
    compile project(':libs:typeface-textview:library')
    compile project(':libs:gpuimage')
    compile 'com.google.android.gms:play-services:4.3.23'
    compile 'com.nineoldandroids:library:2.4.0'
    compile 'com.koushikdutta.urlimageviewhelper:urlimageviewhelper:1.0.4'
    compile ('fr.avianey:facebook-android-api:3.14.0') {
      exclude module: 'support-v4'
    }
    compile 'com.github.japgolly.android:svg-android:2.0.1'
    compile 'org.scribe:scribe:1.3.5'
    compile 'commons-codec:commons-codec:1.8'
}

A: Probably the problem is Base64 class included twice. It is in the 'google-http-client' (view it). Try to exclude this class. If you're lucky, being an Util class, it isn't used in the code.
Try this in your build.gradle:
package com.google.api.client.util;

 sourceSets {
     main {
         java {
             exclude 'com.google.api.client.util.Base64.java'
             exclude 'org.apache.commons.codec.binary.Base64.java'
         }
     }
}

NOTE: I don't tried it yet, but sounds as a possibility

redpajama_set_name: RedPajamaStackExchange


But I found direct address done so invitingly in a short story called Complicity by Julian Barnes in the October 19, 2009 New Yorker, that it got me thinking that it's not time to bury this technique.
I'm sure you're all intrigued about this story by now.
". . .this technique would be absolutely the death of a story if all these questions didn't relate to the theme and the plot. . ."
I'm sure you're all intrigued about this story by now. But this technique would be absolutely the death of a story if all these questions didn't relate to the theme and the plot. But they do. And perfectly. By questioning the reader, the author not only gets you into the protagonist's mind, but into your own storehouse of memories as well. You are engaged, practically married by the time you get to the end.
In playwriting, the technique of addressing the audience (rather than the reader) is called "breaking the fourth wall." The actor steps right downstage, looking out over the audience, and speaks directly to them.
One of the most famous examples of this is Puck's direct address in A Midsummer Night's Dream.
Then think but this and all is mended.
It has been such a hard month.
My cleaning lady…from Brazil…decided that she was depressed one day and stopped cleaning my house.
And—in the meantime—I've been cleaning my house!
I'm sorry, but I didn't go to medical school to clean my own house.
We rarely see direct address in contemporary films, but Woody Allen uses it often. Annie Hall, for example, begins with Alvy Singer (Woody Allen) facing the camera and addressing the audience. His three-minute monologue introduces his childhood. With the adult Alvy's voiceover, we see his mother bringing the young Alvy to the family doctor to discuss Alvy's conviction that since the Universe is expanding and will ultimately end, there's no need to eat or do one's homework.
Allen has continued using direct address in his films. His most recent film, Whatever Works, Larry David, of Curb Your Enthusiasm, playing a Woody Allen-esque alter ego, begins with a conversation he has with the audience.
Poets use this device as well. May Swenson invited the reader to participate in her poem, The Shape of Death, with a question that could be interpreted not only as a direct address to the reader, but a question to herself as well. A literary two-fer, so to speak.
belches from the jaw of fright….
Emily Dickinson also direct address in this first stanza so piquantly, never pounding the reader on the head, rather creating intimacy.
Don't tell! They'd banish me, you know?
". . .direct address can establish a strong connection between the character or subject matter and the audience. . ."
Direct address can establish a strong connection between the character or subject matter and the audience by evoking an emotional response. But when poorly used, it comes across as cornball or even desperation. The audience either doesn't react or boos or closes the book.
What is the ingredient that makes it work? Genius, I'm afraid.
"I might have to write hundreds of words, scores of pages, until I find my beginning. "


10 Inspirational Quotes For A Happy Dating Life!
Zero messages and clicks to your profile, countless meet ups with dating duds or being ghosted, and experiences with soul-crushing breakups can leave you questioning, "What's wrong with me?" You might even engage in negative self-talk statements, such as, "If only I was only prettier, smarter, thinner," (insert self-critical adjective here), then someone would love you.
I get it, you feel disheartened, discouraged, and demotivated. But, before you have a full blown pity party, I wanted to provide some inspiration to rejuvenate your dating esteem.
As part of a free virtual dating summit that I co-hosted with Neely Steinberg from The Love Trep, I was privileged to interview the country's top love experts, therapists, doctors, coaches and authors—people who live and breathe love. They shared their best dating advice for single women of all ages.
I asked each expert for a quote, and was amazed that the majority of them provided words of wisdom that all tapped into the same theme—loving yourself and being yourself.
This resounding message may sound obvious, but it's so hard to do when your confidence and self-esteem are low, especially if you feel shame, embarrassment, guilt, or disgust for parts of yourself.
Everyone has weaknesses, so you must take responsibility for self-improvement, but never compromise on your deal breakers and non-negotiables. Self-love is tied to dating success when you can shift your mindset to believe that the right partner will value, appreciate and cherish you once you can do that for yourself.
The core of healthy dating life comes down to loving who you are.
Rather than telling yourself that you're flawed, unloveable, doomed to be alone forever, or that you're deleting your dating profile and never logging back on, allow these inspirational quotes sink in. Turn inward and commit to exploring, complimenting, and fulfilling yourself.
Speak to yourself with compassion and kindness. Rewrite your negative narratives, challenge your dysfunctional dating beliefs, and learn to love yourself.
Sign up for Samantha's FREE dating summit so that you can watch all 20 expert interviews!
All content is ©2016 Samantha Burns. All rights reserved.


Each year, we ask our CIDM Membership to participate in our annual benchmark study on a buzz worthy topic. This year, we chose metrics. Specifically, we asked information developers to share information on how they gather, measure, and prioritize data. Dawn and Sabine look forward to sharing the results at Best Practices.
Sabine Ocker has 20 years experience working in XML, and more than 15 years architecting, deploying, and migrating structured authoring systems at major companies. She's worked on both Docbook and DITA implementations, and worn many hats—Information Architect, Content Strategist, web site librarian and Enterprise Metadata Czar. Sabine recently joined Comtech Services as a consultant, trainer, and superhero. When not working, Sabine is an amateur Photo Historian and enjoys collecting and talking about vintage snapshots.


text:
El padre François-Xavier Gautrelet (1807-1886) fue un escritor católico francés.

Tesis
Criticó la influencia de la masonería en la revolución francesa contra la religión católica. En 1844 fundo una comunidad católica: l'Apostolat de la prière.

Bibliografía
 l'Apostolat de la prière, 1846.
 La Franc-maçonnerie et la révolution, Lyon, Briday, 1872.
 Le salut de la France par le S. Cœur (1873)
 Le Prêtre et l'Autel (1874).

Notas y referencias

Antimasones de Francia
Escritores católicos

Escritores de Francia del siglo XIX
Escritores en francés


text:
Dichomeris tostella is a moth in the family Gelechiidae. It was described by Stringer in 1930. It is found in Japan, Korea, and the Russian Far East.

The wingspan is . The forewings are yellowish ochreous.

The larvae feed on Malus pumila var. dulcissima, Prunus persica, and Prunus mume.

References

Moths described in 1930
tostella


text:
Kathy Whitney
As Heart Month turns 50, Vanderbilt health educator offers tips for heart health
9 tips for heart health Read More
Hartert to help lead Translational Science efforts
Tina Hartert, M.D., MPH, professor of Medicine in the Division of Allergy, Pulmonary and Critical Care Medicine, has been named assistant vice chancellor for Translational Science. Read More
Heart Institute program aims to reduce readmission rates
Vanderbilt Heart and Vascular Institute is one of 11 centers selected by the American College of Cardiology (ACC) to implement a new program designed to reduce readmission rates for patients with myocardial infarction, heart failure and acute coronary syndrome. Read More
Vanderbilt Heart opens new cardiac procedure area in hospital's critical care tower
From left to right: Charlotte Chaney; Brad Simmons, Turner Construction; Pam Jones; C. Wright Pinson, MBA, M.D.; Keith Churchwell, M.D.; David Posch; Robin Steaban, R.N.; Mark Robbins, M.D.; Mitch Edgeworth, MBA On Feb. 3 the Vanderbilt Heart and Vascular Institute will relocate its key procedure areas to… Read More
Vanderbilt doctors warn against holiday heart attack spike
Studies have indicated that death rates from heart attacks and stroke as well as non-heart-related causes spike during the holiday season. "It is not uncommon to see a heavier patient volume in the hospital during the Christmas and New Year's period of time. Some years that's true,… Read More
Petracek named permanent chair of Cardiac Surgery
Michael Petracek, M.D., has been named chair of Vanderbilt's Department of Cardiac Surgery. Read More
Program helps children with complex care needs
David Hall, M.D., has joined the Monroe Carell Jr. Children's Hospital at Vanderbilt as professor of Clinical Pediatrics and the director of the new Program for Children with Medically Complex Needs within the Division of Hospital Medicine. Read More
Collins recalled as icon of medical education
Robert D. Collins, M.D., professor of Pathology, Microbiology and Immunology, Emeritus, died Nov. 28. He was 85. Read More
Hasselblad, Wilson named to key Heart Institute roles
Ahead of its move into new space on the fifth floor of the Critical Care Tower in February, the Vanderbilt Heart and Vascular Institute has announced two key position changes. Read More
Heart Institute studying absorbable coronary stent
Vanderbilt Heart and Vascular Institute is participating in a clinical trial to evaluate a medical device for the treatment of coronary artery disease. Read More
New faculty: Thomas Wang brings patient-oriented approach to cardiovascular research
Thomas Wang was born in Boston, raised in Boston and educated in Boston. But Vanderbilt's emphasis on personalized medicine in both research and clinical implementation lured him to Nashville. Read More
Framingham Heart Study's landmark impact examined
While the Framingham Heart Study is often referenced throughout the halls of academia, few know its origin or can fully appreciate the contribution it has made to the understanding and prevention of cardiovascular disease. Read More
Vanderbilt Medicine: The sequestration era
Efforts by the federal government to control the nation's spiraling budget deficit, including sequestration that took effect on March 1, have created the potential for significant impact to Medicare's long-standing support for graduate medical education and could limit the ability of the nation's academic medical centers to care for patients and train the next generation of physicians, says Donald Brady, senior associate dean of Graduate Medical Education for Vanderbilt University School of Medicine. Read More
Researchers identify novel biomarker for diabetes risk
Researchers at the Vanderbilt Heart and Vascular Institute and Massachusetts General Hospital have identified a biomarker that can predict diabetes risk up to 10 years before onset of the disease. Read More
Embolism not about to change young singer's tune
As a member of the Tune Town Show Chorus, 20-year-old Kyla Hallums was used to belting out songs and thought it strange when she became short of breath on Sept. 1. Read More
Heart Institute hits ventricular assist device milestone
Cardiac surgeons recently performed Vanderbilt Heart and Vascular Institute's 100th ventricular assist device (VAD) implant. Read More
'Envelope' reduces cardiac implant infections
Vanderbilt Heart and Vascular Institute is the first in the United States to use a new fully resorbable "envelope" that encloses implantable cardiac devices, such as pacemakers and internal cardioverter defibrillators (ICDs), and helps prevent surgical site infections. Read More
New technique eases stroke risk for atrial fibrillation patients
People with the most common irregular heart rhythm known as atrial fibrillation (AF) are at greater risk for stroke due to the formation of clots in the left atrial appendage (LAA), a small pouch which empties blood into the left atrium. Read More
Byrd named president of echocardiography society
Benjamin Byrd III, M.D., professor of Cardiovascular Medicine, has been named president of the 16,000-member American Society of Echocardiography (ASE) for a one-year term following the society's 24th Annual Scientific Sessions, which were held earlier this month in Minneapolis. Read More
Technology allows bedside look inside patients' hearts
Vanderbilt Heart and Vascular Institute physicians are taking advantage of new technology in critical care that allows them to quickly visualize the patient's heart at the bedside. Read More


text:
Q: How to create new row in datagrid after clicking button I have a data grid in xaml:
<DataGrid x:Name="documentsHeadersTableView_table" HorizontalAlignment="Left" Margin="1,1,1,1" VerticalAlignment="Top" AutoGenerateColumns="False" VerticalScrollBarVisibility="Auto">
            <DataGrid.Columns>
                <DataGridTextColumn Header="ON" Width="50" Binding="{Binding documents_Header_ON}"/>
                <DataGridTextColumn Header="Date" Width="120" Binding="{Binding documents_Header_Date}"/>
                <DataGridTextColumn Header="Symbol" Width="100" Binding="{Binding documents_Header_DOCSYMBOL}"/>
                <DataGridTextColumn Header="Number" Width="100" Binding="{Binding documents_Header_DOCNUMBER}"/>
                <DataGridTextColumn Header="Debit" Width="100" Binding="{Binding documents_Header_DEDIT}"/>
                <DataGridTextColumn Header="Credit" Width="100" Binding="{Binding documents_Header_CREDIT}"/>
                <DataGridTextColumn Header="Description" Width="250" Binding="{Binding documents_Header_DESCRIPTION}"/>

            </DataGrid.Columns>

        </DataGrid>

and c# code:
public class User
    {
        public int documents_Header_ON { get; set; }
        public DateTime documents_Header_Date { get; set; }
        public string documents_Header_DOCSYMBOL { get; set; }
        public int documents_Header_DOCNUMBER { get; set; }
        public string documents_Header_DESCRIPTION { get; set; }
    }
private void documentsHeadersListAddingSave_button_Click(object sender, RoutedEventArgs e)
    {int Id_table = Int32.Parse(documentsHeaderAddingOn_textbox.Text);
        DateTime Doc_date = DateTime.Parse(documentsHeaderdate_datepicker.Text);
        string Doc_symbol = documentsHeaderAddingSymbol_textbox.Text;
        int Doc_Number = Int32.Parse(documentsHeaderAddingNumber_textbox.Text);
        string Doc_desc = documentsHeaderAddingDescription_textbox.Text;

        List<User> users = new List<User>();
        users.Add(new User() {documents_Header_ON = Id_table, documents_Header_Date = Doc_date, documents_Header_DOCSYMBOL = Doc_symbol, documents_Header_DOCNUMBER = Doc_Number,
            documents_Header_DESCRIPTION = Doc_desc });
        documentsHeadersTableView_table.ItemsSource = users;
}

After i fill fields with a data(id 1, date, symbol zzz, number 333, description ddd), i press the button, it saves  the entered data to first row.
After I fill fields with next data(id 2, date, symbol www, number 3344, description fff), and press button second time, new data overwrites first row.
How to fix the code to get a new row with new entered data in a data grid after pressing button?


text:
module.exports = function() {
    this.get('/respond').respond();

    this.get('/redirect').redirect('/somewhere-over-the-rainbow');
    this.get('/somewhere-over-the-rainbow').respond();

    this.get('/render').attr('title', 'welcome').render('index');

    this.get('/json').attr('key1', 'val1').attr({
        key2: 'val2',
        key3: 'val3'
    }).json();
};

redpajama_set_name: RedPajamaGithub


Provided you managed to make it back to your luxurious hotel bed after the party ended, you don't need to venture anywhere outside of your own room for the first few hours after waking up. After all, who would want to leave a fluffy pillow and comfortable mattress?
Stillness is the foundation on which swift hangover recovery is based, but if you do make any sudden movements, make sure this incorporates opening your hotel room window to inhale the crisp, fresh air.
It can get awfully cold during the winter, so staying warm is essential to successfully beating the feeling of the Christmas party aftermath. After following step one, the first trip outside of your hotel room should be to the hotel bar.
No, we are not recommending more alcohol to cure your hangover, but instead a hot chocolate, espresso or herbal tea from the hotel bar. Add an extra sugar or two if this is what you need to make it through the day. By this stage, you should be starting to rid yourself of that uneasy feeling.
We're not simply talking about reaching for the trusty bottle of water on the bedside cabinet, but rather treating your body to lots more liquid. Visit the luxury spa located within our hotels to indulge in a revitalising body treatment or aromatic back massage to draw out some of last night's toxins.
The swimming pool is also a good choice, a gentle way to get tired bodies moving again. Alternatively, sweat it out in the sauna or steam room to refresh yourself, if swimming feels like a little bit too much movement.
So you've sweated out yesterday's sins and re-hydrated, now it's time to test the stomach. Depending on just how big your appetite is, following flashbacks of last night, Kempinski's restaurants serve plates for all levels of hunger, so make sure you eat something to make yourself feel better.
Here you can reminisce about last night's antics with colleagues who have made it out of their rooms, although if you were particular badly behaved last night, you may want to use room service instead.
It is at this point that recuperating souls are ready to step outside to successfully conclude their hangover recovery course. By taking a short hike or renting a bike for a few hours, this will ensure individuals breathe in enough fresh air to restore their strength, and wave goodbye to any lingering feelings of tiredness.


text:
Statement by the Prime Minister on Christmas
OTTAWA, ON, Dec. 24, 2020 /CNW/ - The Prime Minister, Justin Trudeau, today issued the following statement on Christmas:
"Merry Christmas, Canada! Today, our family joins Christians across the country and around the world to celebrate the birth of Christ.
"This time of year is full of joy, light, and traditions. As a family, we usually get together to eat too much food, share laughs and stories, watch cheesy holiday movies, give each other gifts, and most importantly, spend quality time together.
"This year, as we continue to deal with the impacts of the global COVID-19 pandemic, Christmas traditions will be different. Families aren't getting together for big dinners and friends aren't stopping by for cookies and eggnog, but we can, and should, give thanks for everything that unites us. Today is a time to recognize all the good that we have in our lives. It's a time to celebrate Christ's message of compassion and show people we love them – and right now, that message is more important than ever before.
"2020 has been a difficult year for all of us, but through it we've seen Canadians meet these challenging times with generosity, kindness, and hope. Neighbours are helping neighbours, kids are giving up play dates and birthday parties, and businesses are retooling their operations, all to help in the fight against COVID-19. We've seen this leadership and dedication from our front line workers, who have put themselves at risk to keep all of us safe and healthy and our families fed. And we also recognize the work of our Canadian Armed Forces members, both at home and abroad, and thank them for their sacrifice and service to our country.
"This year everyone has done their part, because as Canadians we show up for one another. And today, as many spend this holiday away from the ones they love, we need to continue to support and reach out to friends, neighbours, and those in need in our communities. As a country, we will come out of this challenging year stronger and more united, and we will continue to stand together – both today and into the New Year.
"From our family to yours, Hadrien, Ella-Grace, Xavier, Sophie, and I wish you joy, health, and love this holiday season. Merry Christmas, everyone."
This document is also available at https://pm.gc.ca
SOURCE Prime Minister's Office
View original content: http://www.newswire.ca/en/releases/archive/December2020/24/c8798.html
Seeking Safe Income? Preferreds Are Worth a Look as Rates Rise.
These stocks offer solid yields with less price risk than many bonds. Another play for income investors: preferreds issued by mortgage REITs.


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