After hearing that your home inspection may take 2 to 4 hours, you may be inclined to just show up after the inspection is over. Although inspections take some time, depending on the home's square footage, you are at a disadvantage if you do not attend the entire process. Going over the home from top to bottom allows you to learn more about the property and its potential problems.
Allow the inspector to perform the entire inspection without interruption. Constantly asking questions during an inspection distracts the inspector and possibly impedes the process. Instead, hold all of your questions until after the inspection. You can look around the property and make your own notes about concerns. Take pictures to show the inspector after the inspection to verify any issues.
Up until this point, you have probably spent a grand total of 20 minutes on the property. Take some time and visit each room. If possible, sit down and listen to outside noise or internal sounds, such as running water or creaking floor boards. Use this quiet time to determine if there are any hidden issues you want to bring up with the inspector.
If you are planing extensive renovations after purchasing the property, ask painters and flooring professionals to visit the home during the inspection. While the inspector is in another room, professionals can make their own measurements for future repairs or alterations. Do not allow them to change or mark any areas, however. The property is not in your name yet.
When the inspection is finished, go over the report with the inspector. Ask any questions you have been concerned about, even ones that came up when discussing the property with the realtor. Add any personal observations and look at specific areas that may be questionable. Ask the inspector about shut-off valves for gas and water. Take a quick walk around the property to pinpoint problem areas. Clarifying any issues in the report is critical for a successful sale.
The inspector is the only party with an unbiased view of the property. Ask pertinent questions about maintenance, such as homes with hardwood floors or specialized heating systems. Hidden costs may be apparent to the inspector, but not to you. Being absent for a home inspection makes you vulnerable to expensive repairs in the future. Attend the entire inspection to completely understand your new investment.


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Sports Central Message Boards > Professional Sports Discussion > National Basketball Association
Kwame Brown blows ass... and the Lakers are trading for him
Say it ain't so, Phil. Say it ain't so. Ah, but it seems it is so -- that the Lakers are making yet another blunder. I don't want to hear about how Kwame needs a change of scenery or that he's only 23. Fact is this: He's a headcase. He's SOFT. He sucks! And he sure as hell won't pan out like Jermaine O'Neal did.
Phil has his work cut out for him here. Especially if Kwame - perhaps a bigger bust than Olowakandi - can't take the heat from Kobe. Why didn't the Lakers deal Caron for somebody worth a damn? I would've been happy with a Stromile Swift or a Jamaal Magloire. But this? This is a joke, right?
It tastes like... burning.
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Location: San Antonio, Texas
Re: Kwame Brown blows ass... and the Lakers are trading for him
Originally posted by #99
Especially if Kwame - perhaps a bigger bust than Olowakandi - can't take the heat from Kobe.
He should be used to it by now. Michael Jordan screamed and yelled at him all the time while he was still a rookie with the Wizards.
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If you look at his performance since MJ retired, I hardly think you can reason that he has adapted to criticism. He pouts. He whines. The guy is as mentally fragile now as he's ever been.
So basically, he acts like a couple other Pro Athletes I can think of.(No names mentioned). In all seriousness though, I agree. This is one of the reasons I agree with the raising of the age limit. It will help teams to ensure that the young player that they are about to draft will be able to handle the pressure of being scrutinized by an unforgiving press, and having the teams success dependent on them. LeBron James is really the only player I have seen, drafted right out of high school who has managed to act like a professional and keep himself out of the negative spotlight.
Clipps
The Clipper Fan
Yeah. LeBron had a lot of criticism going in his rookie season. haters said he was gunna be a bust, especially after his pathetic performance during preseason in his rookie year.
Get your walk on, Get your head tight
I know your feelin' this ****, Thie **** is damn right
Get your bounce on, Back that ass up.
*****pass me the bottle and fill the glass up
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190 Octane
Kwame averaged 7 points and 5 rebounds the past four seasons. Not exactly earthshaking. I could see him emerging elsewhere like Jermaine O'Neal did in Indiana, but that was with a free agent signing.
Being traded for two players, to a team with a lot of expectations and an angry star isn't the best situation of a youngster to come into his own.
Chicago Bears | Arizona Wildcats | Chicago Cubs | San Antonio Spurs
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Originally posted by Clipps
I'll never criticize a player until he has a couple of years to prove himself, and LeBron proved that point. He's done alot for the Cavs who were pre-LeBron PATHETIC! Kwame...hasn't done much of anything since he's been in. Maybe a fresh start is all he needs but under Kobe?...We'll see how he can handle that. I don't know...
tobynosker
Uh oh...I see a buckeye post blaming Kobe Bryant for the sign and trade deal to bring Kwame Brown in as "the next great Laker center."
In a previous thread I said "Los Angeles is still a major market team with a lot of history that can draw free agents to their organization...players like Kwame Brown could see great intrigue playing with Bryant." In all honestly, Kwame Brown will fit in nice in Los Angeles. Hopefully, he doesn't have to deal with expectations that he cannot live up to like he has for the last four seasons. Why are we so quick to call out Kwame Brown for being such a disappointment? Brown is always the first route people take when arguing for an age-limit in the NBA, because he hasn't lived up to expectations of a number one overall pick. It was the decision of Washington Wizards General Manager Wes Unseld, Doug Collins and Michael Jordan to select the kid number one overall in the 2001 NBA Draft? They were the ones that made the poor business decision in bringing in a young, unproven talent with a terrible attitude.
Regardless of Brown's numbers and attitude, I understand Lakers management decision in taking a chance on the young 23 year old, rather than gambling on Chris Mihm and Vlade Divac for another season. While Brown will never be at the level of Jermaine O'Neal, isn't O'Neal sort of the exception to the rule? I mean, the guy finished second overall in the MVP voting during the 2004 season. Brown will never be an MVP-type player, but the Lakers already have an MVP-type on the floor. They needed a youthful center that can provide 13 points and 8 boards a night when called upon. Brown hasn't done that yet in his career, but again he is 23 years old and a better option than Mihm or Divac.
But, with all that said, it's still a terrible trade. First, because they wasted a draft pick on Andrew Bynum. Their wasn't but one decent center in this entire 2005 NBA Draft, and he was taken first overall. This was a draft filled with a lot of talent at the guard and forward position, and Los Angeles failed to capitalize on that.
Secondly, Caron Butler could have been a strong role player for years to come next to Kobe Bryant. And, I think Butler would have had a better chance at becoming a better player alongside of Bryant and under Phil Jackson than he will in Washington where they have now lost Larry Hughes and Kwame Brown. He was a great third option behind Bryant and Odom. I see him being called upon too often in Washington. Certainly it's not a bad trade on Washington's part trying to fill that scoring need left by Hughes by bringing in Butler, while also dumping the baggage of Brown, but I still see Caron looking for another place to play whenever his contract is up.
Thirdly, who is now going to fill the open hole left by Butler being traded? The resigned Luke Walton? Jumaine Jones? Try and play the rookie Von Wafer?
And finally, why would you trade away Chucky Atkins on top of it? Hopefully from the initial reports, the Wizards will want Devean George over Atkins, because it would work better for both teams. Otherwise, who is your point guard in Los Angeles? Tony Bobbitt?
I have to assume that Phil Jackson, Mitch Kupchak and Jerry Buss have something else in the works, otherwise this team has filled a need while accumalating two more.
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Location: northampton, pa
hey, if anyone could mentor Kwame Brown it's Kobe. right? lol.
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Originally posted by blackdogsong
We'll find out soon. Let's see how it goes.
JayRedd
Jermaine O'Neal's first four seasons
1996 - 4.1 ppg, 2.8 rpg
Then he went to Indiana. I may have overstated Kwame getting to JO level but I still think he'll make a few all-star teams down the road. The kid is young and raw, but he has some skill. And you can't teach that size and atleticism.
"We don't throw at .260 hitters" Jason Varitek, July 2004
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Originally posted by tobynosker
I think you hit it when you mentioned that Kwame never should've been the #1 pick in the first place and that those expectations were thrust upon him, perhaps unfairly. However, there had to have been a reason for all that hype, right? Regardless, whether he was picked 1st or 5th, everyone is justified in calling Brown a giant disappointment. To think that Kwame will be rid of those expectations of having to live up to being a #1 pick is somewhat, but not altogether true. You have a whole new set of expectations when you put on a Laker uniform. Especially when you've been touted to have as much talent as Brown and when the Lakers gave up two quality starters to get him. A whole new set of problems, right there.
Lakers are bombing at every turn since after since hiring Phil (how ironic). Caron Butler never exactly had a place on the team and his future in LA was in doubt since the time of his arrival, but surely you could get more for him than this. I'd be happy to see Devean's contract unloaded and can only assume that Chucky's name is on the table A) because the Lakers are severely handicapped financially and need to dump salary and B) he doesn't jive with Kobe (that second part is actually true - not just a conspiracy theory). Who knows what the free'd up cash can get them. Vujacic looks likely to be the man who would steps in at point guard, but is he ready? Questionable.
I expect Divac will retire before the season starts, but in all honesty, at this stage of the game, I feel far more comfortable with Mihm in the starting lineup than Brown. I also don't believe Brown has proven that he can play center in this league, especially in the West. Hell, I feel more comfortable starting Turiaf at PF than I do Brown. Kwame is a bench player at best, right now. If Phil whips him into shape mentally, maybe he becomes a regular starter. But these dillusions of All Star games are, well, dillusions.
I sure hope you're right and the Lakers have another move planned, because the roster looks worse now than it did last season. Yay. We've added a project and a selfish bust while getting rid of a quality scorer and a servicable point guard. Go team.
No question Washington comes out looking great on this one. I think Butler won't have any trouble filling the scoring void left by Hughes, but his defense compared to Hughes is desperately lacking.
Difference between Kwame and O'neall is that O'Neal had to play behind Brian Grant and Rasheed Wallace most of the time. The Wizards never had the big man depth that the Blazers had in the late 90s. Kwame did have the chance to show what he's all about and all he did was lick ass and suck balls. When O'Neal was finally given the oppurtunity by getting traded to Indiana, he showed up to the moment.
Right on the money, Clipps.
Shawndo
:banghead:
Kwame can't handle people yelling criticism at him (Jordan rode him pretty hard), and Kobe is notoriously harsh on his teammates as well.
Lakers take another gamble and it's starting to feel like when you are on a losing streak at the casino and you start getting desperate to win it back...
But maybe Brown is ready to blossom.. God I hope so.
Now the Lakers need a decent point guard too! Vujacic is still way too green.
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Are Men in Turtlenecks a Holiday Jolly or Folly?
can-men-wear-turtlenecks-holiday-style
By Liana Satenstein
Edited by Ahnna Lee
Men in turtlenecks have long been a contentious subject. Though cozy and even polished when paired with a blazer, the seemingly ideal holiday garb can read surprisingly sinister with its suffocating, neck-choking design and villainous associations. Take Jack Nicholson in The Shining as a wild-eyed and murderous father, swinging an ax while clad in a black turtleneck. On the sleazy side, there's Mad Men's Don Draper as portrayed by Jon Hamm, who embraced a gag-inducing turtleneck and blazer combo as he edged into the '70s—an unnaturally try-hard look for the typically buttoned-up but immoral man, as though he had decided to outwardly embrace his philandering ways. Surprise, surprise, Tom Cruise loves a turtleneck, too: Google "Tom Cruise turtleneck" and the first result is a YouTube video of a freakishly rehearsed Cruise going on about Scientology. Eek on all notes. It's hardly the impression a kind-eyed grandpa or a new beau wants to make at the pre-Christmas holiday party, which might lead one to avoid them entirely.
Yet there's something uniquely powerful about the piece. On the other side of the coin, it references assassins like a dapper Roger Moore as James Bond in a wheat-hued number. For a contemporary version, there's a fearless Matt Damon as Jason Bourne, whose muscles bulge out of a thin knit. Even more recently, off the silver screen, the turtleneck has seen a bit of a resurgence among young men. That so-good-it's-bad look has been hugging the torsos of up-and-coming actors like Timothée Chalamet, who showed up to a premiere for Lady Bird in a festive green turtleneck and black blazer. Zayn Malik, too, has been looking quite dapper in the combo lately, which typically highlights the crooner's grown-up scruff. Ansel Elgort also scored a recent win with a monochromatic gray blazer and turtleneck—a hard-to-pull-off ensemble that instantly matured the cherubic 23-year-old. Hardly gag-worthy, it turns out the turtleneck can rear a pretty chic head. Men: Feel free to accessorize with a blazer—or a glass of eggnog—this holiday season.
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Uttarakhand Blog
If you want to roam on Mall Road of Mussoorie then this news is for you.
manisha raturi January 5, 2021 0
If you want to roam the Mall Road of Mussoorie, then you have to enter the city before five o'clock in the evening. After this, no vehicle will enter the goods road. This decision was taken by Municipal Corporation President Anuj Gupta in a meeting of the councilors and police administration on Monday. It has been decided in the meeting that all parking operators will also put their rate list compulsory.
In the meeting held in the municipality, it has been decided that after five o'clock on Mall Road, the entry of any vehicle other than emergency service will be banned from full thar. Vehicles will be able to enter the parking lots inside and outside the goods road before five o'clock, but all parking operators must compulsorily rate the list. Apart from this, strict action will also be taken on two-wheelers and unnecessarily running vehicles.
The Municipality President has asked the city Kotwal to take action against such vehicles. Municipal Councilors Pratap Panwar, Jasvir Kaur, Darshan Rawat, Kuldeep Rauchela also supported the halt of vehicles on Mall Road after five o'clock.
City Kotwal Devendra Singh Aswal told that no vehicle will get entry on Mall Road after five o'clock. There will be a smart parking system outside the Mall Road. On Saturday and Sunday, if there is no space in smart parking, then vehicles will be sent to the parking lot inside Mall Road.
Mussoorie-Jhadipani bus service people upset:
The Mussoorie-Jharipani bus service has been closed for the last ten months. Due to this, the locals as well as the travelers going to Tehri, Chamba are facing trouble. In view of the problems of the people, Palika chairman Anuj Gupta has written a letter to the Transport Secretary, demanding that the bus service be restarted.
In a letter to the Transport Secretary, Municipal Commissioner Anuj Gupta said that the Dehradun-Jhadipani-Mussoorie and Dehradun-Chamba bus service has been closed for the last ten months due to the Coronation period. Due to which the local people are facing troubles.
He said that several times have been demanded from the officials of the Transport Corporation for the resumption of the bus service, but no action is being taken in this regard. Due to this, job people and students including regional residents are facing difficulties in movement. At the same time, Jharapani resident Prerna Bhandari told that she goes to Dehradun College from Mussoorie, but due to the closure of the bus service, she has to walk to Chunakhala or Kolhukhet.
At the same time, Deepak Jain, General Manager of Transport Corporation in this regard says that due to Covid-19, passengers were not getting on this route. Hence bus operations were discontinued. He said that bus service will be started soon.
#No. 1 Recommended


Summary: When single father Danny Goodman suddenly finds himself unable to afford the private school his teenage daughter adores, he has no one to turn to for financial support.
SUSPICION by Joseph Finder opens with main character Danny Goodman in a financial dilemma. Danny, a widower and father of a teen age daughter, finds himself without sufficient funds to cover her tuition at a pricey Boston exclusive girls' school. In order not to disappoint his daughter, Danny borrows $50,000 from Thomas Gavin, a wealthy Boston money manager and father of his daughter's best friend. At this point Danny's life dramatically changes.
Danny immediately becomes the target of two DEA agents. He learns that Gavin handles billions of dollars for a ruthless Mexican drug cartel. Danny must decide to co-operate and cope with the risk of the drug cartel finding out or face an indictment for money laundering. Danny decides to cooperate. He's first task for the DEA is to plant a listening device in Gavin's office and later he downloads information from Gavin's phone. Danny finds himself in a constant state of anxiety and having to regularly lie to both his daughter and girlfriend. His assignment is further complicated when he and Gavin become friends. Danny finds the determination to calm himself and devises a plan to end this nightmare and salvage the relationships with his girlfriend and daughter.
SUSPICION is a typical thriller where ordinary people are put into heroic situations; there's plenty of violence and death; and the ending is a surprise after following the mandatory twists and turns. The author does differentiate himself from other thrillers with his strong character development and a well-paced and suspenseful storyline.
Although SUSPICION offers nothing particularly unique to the thriller genre, it's a good page turner that will be enjoyed by anyone who likes a good suspense thriller.
It sounds like you both liked this book a lot so I'll have to look for it.
I like the Nick Heller series by this author. This one sounds good too.


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Home » Other tech: nanoscale superconducting wire for fast optical communication and long distance quantum encryption
Other tech: nanoscale superconducting wire for fast optical communication and long distance quantum encryption
April 7, 2017 January 31, 2006 by Brian Wang
Optical communication in space at 8X ethernet speeds and longer distance quantum encrypted communication could result from a better photon trap
A photon trap. The heart of the detector, which has been around for a couple of years, is a wire 100 nanometers wide that meanders like coils on a refrigerator to increase the area of detection. The wire is cooled to just above absolute zero, at which temperature it becomes a superconductor. When a photon hits the wire and is absorbed, the wire heats up just enough to stop superconducting, creating a detectable jump in resistance.
In the new design, the photons that slip past or reflect off the wire bounce around in the photon trap, giving them more chances to be absorbed by the wire. The trap, with a little help from an antireflective coating, approximately tripled the efficiency of previous detection efforts.
Drop-off in the number of photons limits the range of quantum cryptography to 100-150 kilometers. But, according to Michael LaGasse, vice president of engineering at the Somerville, MA, labs of MagiQ, which is already commercializing quantum cryptography, a detector as efficient as Berggren's could double or triple these distances. Because of cost considerations, however, LaGasse says the new detectors are likely to find only niche markets, such as in military applications.
Other Tech: Antimatter harvesting
Other tech: Laser acceleration of ions


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Eric Church Lights Up The CMAs With "Heart on Fire"
Twitter / CMAs
The reigning CMA Entertainer of the Year has returned to the stage to deliver a truly one-of-a-kind performance of his most recent single — and folks ate it up!
THEN ➡ NOW of #CMAawards Entertainer of the Year nominee, @EricChurch 🌟 What is your favorite Eric Church moment? Tell us below! pic.twitter.com/BRLVv3xU5q
— CMA Country Music (@CountryMusic) November 2, 2021
Last year's CMA awards featured performances from some of the biggest names in the industry and they didn't hold back for 2021, either.
You know what else would be a "Hell Of A View"? Watching Song of the Year nominee @EricChurch performing on the #CMAawards stage on Wednesday, Nov. 10 at 8/7c on @ABCNetwork! 😎 pic.twitter.com/MUyXjyjAjb
— CMA Country Music (@CountryMusic) October 29, 2021
Alongside Eric Church, tonight's show featured collaborations from Jason Aldean and Carrie Underwood, Carly Pearce and Ashley McBride, performances by Luke Bryan, Miranda Lambert, Keith Urban, Blake Shelton, and even Chris Stapleton.
To say that the evening was filled with great music is an understatement.
Church, who is nominated for both Entertainer of the Year and Male Vocalist of the Year, gave his latest single "Heart on Fire" the CMA treatment and dazzled the crowd with his performance.
Check out this fiery-hot performance in the clip below!
Previous article 2021 CMA Awards – The Song Of The Year Winner Is…
Next article Who Is Eric Church's Backup Singer That Just Stole The Show?
"Yellowstone" Producer Says When Season 5 Will Air
It was lined up to be a summer series, but the COVID-19 pandemic threw a wrench into the Season 4 plans, so it became a Fall show.


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Mainly Clear 26°. Wind Chill: 25°. Wind: W 6 mph.
Home » ABC Politics » Army veteran to become first living recipient of Medal of Honor for war in Iraq
Army veteran to become first living recipient of Medal of Honor for war in Iraq
(WASHINGTON) — The White House announced on Monday that former Army Staff Sgt. David G. Bellavia will become the first living Medal of Honor recipient for the war in Iraq for his heroism during the second battle of Fallujah in November 2004. The five previous Medals of Honor in the Iraq War were handed out posthumously and Bellavia's award is an upgrade from the Silver Star he had previously received. President Donald Trump will present the award to Bellavia at a White House ceremony on June 25. Bellavia is being honored for his heroism on Nov. 10, 2004 when he was a squad leader in Operation Phantom Fury, an American offensive on the western Iraqi city of Fallujah, an Iraqi insurgent stronghold. The Army veteran is credited with saving his entire squad that day after being pinned down by enemy fire coming from a block of houses. "He quickly exchanged an M16 rifle for an M249 Squad Automatic Weapon, entered the house where his squad was trapped, and engaged insurgents, providing cover fire so that he and his fellow soldiers could exit safely," said a White House statement announcing his award. When an armored Bradley Fighting Vehicle could not fire directly into the house, Bellavia re-entered the house armed only with an M16, and attacked insurgents who had been firing rocket-propelled grenades. "He proceeded to kill one insurgent and wound another, who then ran to another part of the house," said a White House statement announcing his award. "Then-Staff Sergeant Bellavia was soon engaged by another insurgent rushing down the stairs when the previously wounded insurgent reemerged to engage him as well."
Bellavia was able to return fire and killed both attackers. "He then took enemy fire from an insurgent who had appeared from a closet across the room. He pursued him up the stairs and killed him," said the statement. Bellavia then went to the roof "where he engaged and wounded a fifth insurgent, who fell from the roof of the building." For his heroism, Bellavia was awarded the Silver Star, the nation's second highest award for valor. His award is being upgraded to the Medal of Honor as part of the Pentagon's review of valor awards. Bellavia enlisted in the United States Army in 1999 and after serving in Kosovo, he deployed to Iraq in 2004 with Company A, Task Force 2-2, 1st Infantry Division. Since leaving the Army in August 2005, Bellavia has been active in veterans advocacy groups and philanthropic organizations. Copyright © 2019, ABC Radio. All rights reserved.


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5.21.2017 Billboard Music Awards News
Drake Squashes Beef with Ludacris at Billboard Music Awards
After making peace with Tory Lanez, Drake squashed his beef with another former foe, Ludacris, at the Billboard Music Awards on Sunday (May 21).
Taking the stage at the T-Mobile Arena in Las Vegas, Drake accepted his award for Top Billboard 200 Album for Views by explaining the importance of living in the moment. In that spirit, he celebrated the BBMA host, Luda.
"Ludacris, we haven't always seen eye to eye, but I've always been a big fan of yours and I got a lot of love for you," he said. "I want to let you know that face to face, while I'm still here."
https://twitter.com/BBMAs/status/866464194396274689
Ludacris and Drake sparked their public rivalry in 2011, when Drizzy appeared to make fun of the "Southern Hospitality" rapper's use of the "Supa Dupa" flow that Big Sean, Drake, Nicki Minaj, Lil Wayne, and others used prominently. "I hate that rappers picked that flow up," he told AllHipHop. "I wish they had left that for people that know how to use it."
After Sean made similar comments in reference to Luda, 'Cris clapped back on "Bada Boom." "Counterfeit rappers say I'm stealing they flows," he rapped. "But I can't steal what you never made up, bitch."
After that, Drizzy alluded to a female companion who was also seeing Ludacris on "How About Now" off 2014's If You're Reading This It's Too Late. "I used to always try and burn you CDs of my new shit," he raps on the track. "You be like, 'Who's this?' / I'd be like, 'Me, girl,' You be like, 'Oh, word, true shit?' / Then ask if we could listen to Ludacris / Them car rides made me feel like I was losin' it."
The following year, Luda would say that the line came from real life events. "I think there is a little bit of a true story behind that," he told "The Breakfast Club." "His girl, at the time, with all due respect was probably doing a little bit more than that. It's a true story and I think that's why he said that."
Apparently, this wasn't the first time Drake made peace with 'Cris. "Me and Drake had our thing," Luda told "The Breakfast Club" during the same 2015 interview. "He came to me and apologized to me like a man."
But this wasn't the only thing that the 6 God had to get off his chest. He also praised Vanessa Hudgens for her looks after explaining what inspired his speech.
"I had a close friend of mine that didn't support my album but then supported other peoples' stuff," he said. "I asked him why and their response was, 'I don't want to look thirsty. You get enough love as it is.' It made me think. It's crazy that, we're all here on Earth for a limited amount of time and we gotta show love while we're here. So, tonight, I want to say Vanessa Hudgens, you look incredible tonight."
It didn't end there, as the OVO head also gave love to his Young Money family, who he sat beside in the front row. "I want to say, Nicki Minaj, I'm so glad we found our way back because I love you and I could never ever see it any other way," he added. "I want to say, Lil Wayne, if it wasn't for the risk you took, none of us would be here tonight."
Young Mula, baby! #BBMAs pic.twitter.com/5PjJ3WMHUM
— Rap-Up (@RapUp) May 22, 2017
Finally, Drizzy had to send some love to his father, Dennis Graham, for his dapper style. "And I want to say, my dad got on a purple suit with purple shoes," he added. "Boy, if you don't stop!"
Drake — who led all nominees with 22 nods going into the evening — has 12 wins at press time. Tonight, he's also set to make a rare award show performance splash with a "very big moment."
Camila Cabello Performs 'Crying in the Club' at Billboard Music Awards
Ain't no crying at the Billboard Music Awards. Hot off the release of her new solo singles "Crying in the …
Watch Drake Perform 'Gyalchester' in the Bellagio Fountains
Drake brought the fireworks—and the waterworks—to the Billboard Music Awards. After watching his Young Money labelmate Nicki Minaj open the …


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A new trail along the E-470 corridor needs a name and officials want you to name it
By: Oscar Contreras
ARAPAHOE COUNTY, Colo. – A regional trail along the west side of E-470 was recently built in Arapahoe County, but the thing is that it doesn't have a name.
Now, Arapahoe County officials hope you can help them name the trail through the Democratic process of an online poll.
The trail, which officials say is a "tremendous asset" to the community as it would eventually connect the E-470 trail with the Cherry Creek Trail to the south and the Plains Conservation Center to the north, is not without a few options for the name.
The following names were provided for you to choose from:
High Plains Trail
Long View Trail
Pioneer Trail
Prairie Trail
Bison Beltway
To make your voice heard and to help the decide the future of the trail's name, you can vote by clicking this link to head over to the Arapahoe County Trail Naming Poll website .
If you vote and provide your contact information, you will be entered in a raffle to win a Garmin GPS watch.
Is E-470 building a bike path to nowhere?
The project currently runs from Quincy to south to Ireland Way, leaving about a 2.5-mile gap of pretty much nothing.
The final connecting piece of the trail is now in the hands of the local governments, including the Town of Parker.
Completion of that part of the trail could take about five years.


CHICAGO, Ill. -- The Purdue University Calumet women's tennis team swept Chicagoland Collegiate Athletic Conference foe Robert Morris University 7-0 on Wednesday afternoon.
The match was shortened due to unavailable court time at Chicago's East Bank Club.
Ashley Pabey (East Chicago, Ind./East Chicago) picked up the victory at No. 2 singles against RMU's Page Seldal, 8-1, while teammate Emily Pearson (Hammond, Ind./Morton) also won at No. 4 singles against RMU's Brianna Jones, 8-3.
Pabey and Haas were able to pick up the victory in No. 1 doubles, 8-6, defeating RMU's Gvansta Robakidze and Page Seldal.
Kasey Kulesa (Munster, Ind./Munster) and Sarah Dingman (Schererville, Ind./Lake Central) got the win at No. 2 doubles, 8-6, defeating the Eagles' Nicole Witczak and Brianna Jones.
No. 1 singles' Lori Haas (Bismarck, Ill./Bismarck-Henning) and No. 3 singles' Cynthia Basu-Chavez (Merrillville, Ind./Merrillville) were unable to finish their matches due to unavailability of the courts.
The Peregrines return home Saturday with a single match, taking on CCAC foe St. Francis (Ill.) at 10 a.m., followed by a double match with Calumet St. Joseph at 10 a.m. and St. Ambrose at 2 p.m. at Dowling Park's Community Hospital Tennis Complex.
SINGLES: -- 1. Lori Haas vs. Gvantsa Robakidze (unfinished); 2. Ashley Pabey def. Page Seldal, 8-1; 3. Cynthia Basu-Chavez vs. Nicole Witczak (unfinished); 4. Emily Pearson def. Brianna Jones, 8-3; 5. Kasey Kulesa won by default; 6. Selina Baez won by default.
DOUBLES: -- 1. Haas/Pabey def. Robakidze/Seldal, 8-6; 2. Dingman/Kulesa def. Witczak/Jones, 8-6; 3. Pearson/Basu-Chavez won by default.


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Prospect Elementary School is getting a math library. The K-5 school recently received a $2,500 grant through Farmers Insurance's Thank A Million Teachers program to develop a math library. It is one of six schools in the eastern region to receive grant funding.
The library, which will be located in a teacher work room that was being used for student interventions, will hold games, instructional materials, lessons, literatures, manipulatives and mathematical tools. Educators will collaborate to build meaningful lessons, provide opportunities to differentiate instruction and share resources.
Fourth grade teacher Melissa Bennett wrote the grant proposal. She came up with the idea after participating in a professional development program organized by Donna Russell, a systemwide math coach.
"I sat down afterward with a co-worker, and we started talking about how nice it would be to provide these instructional opportunities to our students," Bennett said. "I started looking at grant opportunities the next day."
After discovering some grant programs that could meet her school's needs, the teacher started writing grant proposals, armed with the knowledge she learned in a grant writing workshop offered by librarian Lelia Rogers. She specifically liked Farmers Insurance's Thank A Million Teachers program, which awarded grants based upon online voting results.
"Once it went live in November, I contacted parents and teachers, posted information on Facebook and reached out to our local Farmers Insurance agency," Bennett said. "Drew Miles returned my email and met with me to discuss the proposal. It just kind of took off from there."
"Farmers Insurance is a family, and I look at my clients like family members," said Drew Miles, principal of Drew Miles Agency — Farmers Insurance Group. "After I found out about this grant proposal, I reached out every day to all of my clients, family, friends and business partners about the online voting."
'Empower students'
For the contest's first 25 days, Bennett tracked the proposal's voting results. Students graphed results every day, noting increases and decreases and projecting final results. Prospect Elementary's proposal was ranked in the top tier for 25 days, then the site went dark for the last five days. Nobody knew whether the proposal would remain atop the others and get funded. When the final results were revealed, Prospect Elementary had received a $2,500 grant.
"I couldn't have been more proud of them," Miles said. "They put so much energy into this program. It's rewarding for me to know this money will directly benefit children. I hope they'll be able to empower students and create a passion for math. Everything we do as adults is tied to math principles whether it's budgeting or building a house. I hope this math library opens their eyes to what's out there."
The math library will accomplish that goal by providing educators with the resources to make lessons more meaningful, Bennett said. "Every student has different needs, and we'll be able to meet them now. By pooling resources in the math library, we'll be able to fill in those gaps wherever a child has them. We'll also be able to challenge our more advanced students. The sky is the limit now."
Mathew Stewart - The Daily Times


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Lawmakers Weigh Investigation Into Jewish University Over $230 Million In State Funding
New York state senators threatened an investigation Wednesday into allegations that Yeshiva University misrepresented itself to receive $230 million in state funding, according to a letter sent to the Jewish school.
Yeshiva is currently embroiled in a lawsuit regarding the school's refusal to officially recognize the YU Pride Alliance, an LGBTQ student club, on campus due to its religious convictions. Democratic state Sens. Brad Hoylman, Liz Krueger and Toby Ann Stavisky accused Yeshiva Wednesday of misrepresenting itself as an "independent, coeducational, nonsectarian" institution in 2009 and 2011 to receive $230 million in public funding via the Dormitory Authority of the State of New York (DASNY) despite the university arguing that it is a "religious" organization in its lawsuit with YU Pride Alliance.
The letter explained that DASNY had issued bonds to the university in 2009 and 2011 to pay for renovations of the buildings and grounds, but the senators noted that to receive those bonds YU agreed to certain stipulations for the use of the funding. Those stipulations required the university to use the DASNY funding for secular purposes only, but the senators alleged that YU failed to abide by this requirement. (RELATED: New York Appeals Court Rules Yeshiva University Must Recognize LGBTQ Student Group)
"The University agrees that … the Project or any portion thereof shall not be used for sectarian religious instruction or as a place of religious worship or in connection with any part of a program of a school or department of divinity for any religious denomination; provided, however, that the foregoing restriction shall not prohibit the free exercise of any religion," the letter read.
The letter further demanded that Yeshiva provide a "full and complete accounting" of its use of DASNY funding within 30 days. All three senators also called for the university to change its "anti-LGBTQ policies."
"We will not abide the use of state funds to support discriminatory behavior that excludes LGBTQ students from their right to an equal education," the senators wrote. "We urge Yeshiva University to immediately reverse course and cease its anti-LGBT policies."
NEW YORK, NEW YORK – AUGUST 30: People walk by the campus of Yeshiva University in New York City on August 30, 2022 in New York City. (Photo by Spencer Platt/Getty Images)
Hanan Eisenman, a Yeshiva University spokesperson, told the Daily Caller News Foundation that the Supreme Court had upheld the right for universities to provide a "world-class academic and professional education" in the context of a "religious education."
"In the last five years, including this past summer in Carson v. Makin, the Supreme Court has three times ruled that the government may not restrict funding to religious schools because of their free exercise," Eisenman stated. "Yeshiva will continue to defend its right to religious liberty while ensuring the right of its students to be treated by the state on equal footing with students at every other university."
The senators claimed that the lawsuit between Yeshiva and the YU Pride Alliance raised questions as to how the university could receive public funding for only non-religious entities while engaged in a lawsuit in which the university argued it was primarily a religious and educational institution.
Eisenman resoundingly denied this accusation, calling it "false and offensive."
"Our students, including our LGBTQ students, come to Yeshiva because of our commitment to Torah values," Eisenman pointed out. "In keeping with our commitment to our students, YU last year announced the framework for the Kol Yisrael Areivim club for our undergraduate students who identify as LGBTQ and are striving to live authentic Torah lives."
Yeshiva, Hoylman, Krueger and Stavisky did not respond to DCNF's request for comment.
All content created by the Daily Caller News Foundation, an independent and nonpartisan newswire service, is available without charge to any legitimate news publisher that can provide a large audience. All republished articles must include our logo, our reporter's byline and their DCNF affiliation. For any questions about our guidelines or partnering with us, please contact licensing@dailycallernewsfoundation.org.
HEAD: The Left's Hidden Offensive Play Against Religious Freedom
US To Boost Military Presence On Island Nation To Counter China Threat: REPORT


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Let's Abolish The Third World
By Newsweek Staff	 On 4/26/92 at 8:00 PM EDT
Sometimes language lags history. Take the Third World. Did we ever have another name for the poor, unstable nations of the south? In fact, the Third World is a 1950s coinage, invented in Paris by French intellectuals looking for a way to lump together the newly independent former European colonies in Asia and Africa. They defined le tiers monde by what it wasn't: neither the First World (the West) nor the Second (the Soviet bloc). But now the cold war is over, and we are learning a new political lexicon, free of old standbys like "Soviet Union" that no longer refer to anything. It's a good time to get rid of the Third World, too.
The Third World should have been abolished long ago. From the very beginning, the concept swept vast differences of culture, religion and ethnicity under the rug. How much did El Salvador and Senegal really have in common? And what did either share with Bangladesh? One of the bloodiest wars since Vietnam took place between two Third World brothers, Iran and Iraq. Many former colonies remained closer to erstwhile European metropoles than to their fellow "new nations." Nevertheless, the Third World grew. Intellectuals and politicians added a socioeconomic connotation to its original geopolitical meaning. It came to include all those exploited countries that could meet the unhappy standard set by Prime Minister Lee Kuan Yew of Singapore in 1969: "poor, strife-ridden, chaotic. " (That was how Latin America got into the club.) There's a tendency now to repackage the Third World as the "South" in a global North-South, rich-poor division. To be sure, in this sense the Third World does refer to something real: vast social problems-disease, hunger, bad housing matched by a chronic inability to solve them. And relative deprivation does give poor nations some common interests: freer access to Western markets, for example.
But there are moral hazards in defining people by what they cannot do or what they do not have. If being Third World meant being poor, and if being poor meant being a perennial victim of the First and Second Worlds, why take responsibility for your own fate? From Cuba to Burma, Third Worldism became the refuge of scoundrels, the "progressive" finery in which despots draped their repression and economic mismanagement. Remember "African socialism " in Julius Nyerere's Tanzania? It left the country's economy a shambles. A good many Western intellectuals hailed it as a "homegrown" Third World ideology.
Paternalism is one characteristic Western response to a "victimized" Third World. Racism is another. To nativists such as France's Jean-Marie Le Pen or Patrick Buchanan, "Third World" is a code phrase for what they see as the inherent inferiority of tropical societies made up of darkskinned people. Either way, the phrase Third World, so suggestive of some alien planet, abets stereotyping. "The Third World is a form of bloodless universality that robs individuals and societies of their particularity," wrote the late Trinidad-born novelist Shiva Naipaul. "To blandly subsume, say, Ethiopia, India, and Brazil under the one banner of Third Worldhood is as absurd and as denigrating as the old assertion that all Chinese look alike."
Today, two new forces are finishing off the tattered Third World idea. The first is the West's victory in the cold war. There are no longer two competing "worlds "with which to contrast a "third." Leaders can't play one superpower off the other, or advertise their misguided policies as alternatives to "equally inappropriate" communism and capitalism. The second is rapid growth in many once poor countries. The World Bank says developing countries will grow twice as fast in the 90s as the industrialized G-7. So much for the alleged immutability of "Third World" poverty-and for the notion that development must await a massive transfer of resources from north to south. No one would call the Singapore of Lee Kuan Yew poor, strife-ridden or chaotic: per capita GNP is more than $10,000, and its 1990 growth rate was 8 percent. South Korea, Taiwan and Hong Kong also have robust economies, and Thailand and Malaysia are moving up fast.
American steelmakers have recently lodged "dumping" complaints against half a dozen Asian and Latin American countries. Cheap wages explains much of these foreign steelmakers' success, but the U.S. industry's cry is still a backhanded compliment. "A nation without a manufacturing base is a nation heading toward Third presidential candidate Paul Tsongas. But Tsongas was using obsolete imagery to make his point: soon, bustling basic industries may be the hallmark of a "Third World" nation.
Nor can the Third World idea withstand revelations about what life was really like in the former "Second World. " It was assumed that, whatever the U.S.S.R.'s political deformities, that country was at least modern enough to give the West a run for its money in science and technology. In fact, below a patina of modernity lay gross industrial inefficiency, environmental decay and ethnic strife. Nowadays, it's more common to hear conditions in the former Soviet Union itself described as "Third World," and Russia seeks aid from South Korea. Elsewhere in Europe, Yugoslavia's inter-ethnic war is as bad as anything in Asia or Africa. The United States itself is pocked with "Third World" enclaves: groups with Bangladeshi life expectancies and Latin American infant-mortality rates.
A concept invoked to explain so many things probably can't explain very much at all. The ills that have come to be associated with the Third World are not confined to the southern half of this planet. Nor are democracy and prosperity the exclusive prerogatives of the North. Unfair as international relations may be, over time, economic development and political stability come to countries that work, save and organize to achieve them. Decline and political disorder come to those who neglect education, public health-and freedom. The rules apply regardless of race, ethnicity, religion or climate. There's only one world.
Let's Abolish The Third World | News


As you know, memory has a way of fading. By documenting employee performance at the start of the assessment period, you can avoid pitfalls such as evaluating employees solely based on recent performance or making an overly subjective assessment given a lack of factual information.
It might seem like a lot of work at first, but evaluating employee performance will be much quicker and simpler if you already have all the information when that time rolls around.
And EVO.K.E makes it much easier with its handy "Add a note" feature (button in the lower-left corner of the screen).
It's important to take notes about examples of specific behaviour, whether positive or negative.
Record the facts, such as the date and the individuals who were present. These details will help you support your arguments and stay objective during the assessment meeting. Your notes might even come in handy if you need to manage a difficult employee.


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Home » CELLULOSE AS SOLE SUBSTRATE FOR BIO ETHANOL PRODUCTION: DEVELOPMENT OF STRUCTURAL MOLECULAR MODEL OF ENDOGLUCANASE III FROM TRICHODERMA REESEI USING BIOINFORMATIC TOOLS
CELLULOSE AS SOLE SUBSTRATE FOR BIO ETHANOL PRODUCTION: DEVELOPMENT OF STRUCTURAL MOLECULAR MODEL OF ENDOGLUCANASE III FROM TRICHODERMA REESEI USING BIOINFORMATIC TOOLS
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Chandrasekhar and B. Bhima*
Department of Microbiology, University College of Science, Osmania University, Hyderabad, India
ABSTRACT: One of our greatest challenges in improving nation's economy is to reduce the dependence on imported petroleum products. To accomplish this, we need a variety of alternative fuels, which includes ethanol produced from cellulosic materials. Cellulose is a rich natural biopolymer on earth and most dominating agricultural waste. Apart from the fossil fuels, bioethanol is used as chief renewable energy source found on earth. Hence, we developed the structural molecular model of the endoglucanase III from Trichoderma reesei by homology modelling using Modeller 9v12. Based on sequence similarity with protein of known structure (PDB ID: 1H1N) was chosen from PDB by using protein BLAST. The models were evaluated by PROCHECK. Resulted Ramachandran plot analysis showed that conformations for 99% of amino acid residues are within the most favored regions. A possible active site was identified in the model using Sybyl6.7. The predicted model permits initial inferences about the unexplored 3D structure of the endoglucanase III and may promote in relational designing of molecules for structure-function studies.
Bio Ethanol, Docking, Endoglucanase III, Homology modelling, Trichoderma reesei
INTRODUCTION: Biofuels provide a potential route for avoiding the global political instability and environmental issues that arise from reliance on petroleum. At present, most of the biofuel is in the form of ethanol generated from sugar or starch, but this can meet only limited areas of global fuel requirements 1. To reduce the energy cost, low-acid/temperature pretreatments 2 were attempted, but it is still necessary to add large amounts of cellulolytic enzymes to hydrolyze the cellulose material. In this current study Endoglucanases were engineered for broad specificity, pH, temperature and activity.
Endoglucanases cut at random at internal amorphous sites in the cellulose polysaccharide chain, that generates oligosaccharides of various lengths and consequently new chain ends. As endoglucanase (EG) is a key component of cellulase which it degrades the cellulose material, a polymer to be smaller monomers and have been used in various industries like textiles, fruits and vegetable processing, and recently in bioethanol production 3.
Due to these essential applications of endoglucanase, and remaining cellulases various protein engineering approaches have been employed to enhance the functional properties of these enzymes to achieve better performance 4. As ethanol production is cheaper than liquid petroleum, the production of ethanol depends on simultaneous saccharification of cellulose to glucose and fermentation of glucose to ethanol by a recombinant yeast strain as a microbial biocatalyst. Recombinant yeast strain expressing endoglucanase and β-glucosidase was able to produce ethanol from β-glucan, CMC and acid swollen cellulose 5.
Yeast cell-surface is a technique used in protein engineering that enables 104–105 enzymes to be displayed on the surface of a yeast cell 6. The surface displayed yeast can be used as a whole-cell biocatalyst without requiring enzyme-separation and purification processes, and it can immediately in take glucose degraded from cellulose and thus, it is hardly contaminated by other organisms. Furthermore, direct fermentation to ethanol from cellulose could be conducted by using cellulase surface displaying yeast 7. This reduces the chance of contamination and high efficiency of product yield with low economic value of bioethanol production 8.
METERIALS AND METHODS:
Query Retrieval and Template recognition:
The protein sequence of endoglucanase of "Trichoderma reesei" was retrieved from NCBI database (National Center for Biotechnology Information) which have 418 amino acid residues, accession number (Genbank id) is AAA34213.1 for modeling. Homology modeling usually starts by searching the PDB (Protein Data Bank) of known protein structure using a query sequence. This search is generally performed by comparing the target sequence with the sequence of each of the structure in the database. The protein sequence of 1HIN (template) worked as a target sequence. For identification of appropriate template BLASTp was performed against Protein Data Bank, select templates for generating the putative 3D structures.
Homology Modeling:
The method of comparative modeling requires identification of homologous sequences with existing structure. The first step of comparative/homology modeling, scanning and selection of template protein structure was carried out using the target sequence as query 9. A sequence similarity search by BLAST program was carried out with query sequence against proteins whose solved structures had been deposited in the Protein Data Bank (PDB) to find related proteins as templates. BLASTp generally used for template selection procedure [http: //blast.ncbi.nlm. nih. gov/ Blast] 10. The BLAST analysis outputted potential template for modeling is 1H1N, the high degree of primary sequence identity (99%) between target and endoglucanase III indicates that this crystallographic structure was good model to be used as template for endoglucanase III enzyme.
The alignment of the endoglucanase III target and 1H1N is shown in (Figure 1). A total of 20 models were generated using program MODELLER 9.11. MODELLER implements comparative protein modeling by satisfaction of spatial restraints. Comparative initial alignment was done by using clustalX. 11
FIGURE 1: ALIGNMENT OF QUERY SEQUENCE (AAA34213.1) AGAINST THE TEMPLATE PDB (PDB ID: 1H1N)
Model analysis:
Modeller generated the 20 models for the same target, out of which the best model can be selected for further analysis. We evaluated the model with the lowest value of the Modeller objective function and PROCHECK results. The stereochemical quality of the developed models for endoglucanase III enzyme using Ramachandran's plot calculation computed with PROCHECK 12.
Structure Visualization and structural analysis
Visualization and Structural analysis of final protein model were carried out with Swiss PDB Viewer (spdbv) 13 software. Structural alignment and Root Mean Square Deviation (RMSD) calculation with several models and template were carried out with spdbv.
Active site analysis:
The SITE ID module of Sybyl 6.7 13 is a suite of programs for identifying and characterizing binding sites and functional residues from protein structure. In this study, the active site search program was used to search the protein binding sites by locating binding pockets studied structure. Through comparing the conserved residues in family of the studied protein and combining the search results and other experiment results, the binding sites of Endoglucanase III were predicted. Those results were used to guide the following docking experiment.
Molecular Docking Studies:
FlexX automated docking software used for docking simulation 14 installed on Silicon Graphics Inc octane2 workstation using the package SYBYL 6.715 to investigate the binding mode between the inhibitors and Endoglucanase III receptor. The flexible docking program uses incremental construction algorithm, which employs the preparation of receptor by adding hydrogen's and assigning Gasteiger Huckel charges, and saved it in PDB file. The ligand cellulose was minimized by assigning Gasteiger charges and non polar hydrogen's. The incremental construction algorithm is known to be the most efficient and reliable method of FlexX.
RESULTS AND DISCUSSION:
Model building, refinement and evaluation:
In the present study, the primary sequence identity between endoglucanase (target) and Trichoderma reesei indicates that ~90% sequence identity. Medium accuracy model, obtained with a template-target sequence identity of 50-60%. The sequence analysis result based on BLASTp, a number of models had been generated for each binary complex and the final model selected based on MODELLER objective function.
In the current research work, experimental structure of endoglucanase of Trichoderma reesai is not available in Protein Data Bank (PDB), homology modeling approach was used in order to derive their structure. BLAST search results had shown higher similarity with crystal structure of IHIN, while the template was selected on the basis of higher sequence identity. It shows 99.0% sequence identity, with maximum conserved residues. Comparative modeling predicts the 3-D structure of endoglucanase III model of given protein sequence (target), based primarily on this alignment to the template. The developed model was also checked for phi and psi torsion angles using Procheck for Ramachandran plots.
All together 98% of the residues were found to be in core and allowed regions, which validate the quality of predicted homology models. Visualization and analysis of the model using Swiss PDB Viewer (spdbv) reveals that there are no steric hindrances between the residue and thus modeled structure are stable. Target structure-template structure superimposition was done in order to calculate Root Mean Square Deviation (RMSD) between the target and template sequence. This implies good quality of the modeled structure (Figure 2) and ramachandran plot (Figure 3) of Endoglucanase III.
FIGURE 2: MODELLED PDB STRUCTURE OF THE ENDOGLUCANASE III
FIGURE 3: RAMACHANDRAN PLOT FOR MODELLED ENDOGLUCANASE III.
Modeled endoglucanase III enzyme were docked against cellulose (Figure 4). The ligand interacts with seven amino acids and showing around 20 interactions. The low binding energy values of endoglucanase enzyme indicate that the ligands are in most favorable region of the protein and that the enzyme has more affinity towards the ligand cellulose. Gly92, Asn99, Gly235, Gly379, Arg417 and Lys418. Among all these seven interactions Arg417 shows highest number of interactions (nine interactions), Gly92 shows 5 interactions and rest of the amino acids shows 2-3 interactions. All the interactions are shown in Figure 4.
FIGURE 4: CELLULOSE INTERACTIONS WITH ENDOGLUCANASE III.
CONCLUSION: In the present study, As Endoglucanase is the key enzyme that degrades polymer cellulose to trimer and tetramers in which combination of two enzymes (cellobiohydrolase & β-glucosidase) convert it to bioethanol. The 3D model of Endoglucanase III has been constructed from Trichoderma reesei, using the Homology modelling approach. Molecular docking studies of cellulose with Endoglucanase III exhibited binding interactions and warrants further studies needed for the development of potent endoglucanase III inhibitor. This data provides molecular insights for the consideration of cellulose as potential candidate against Endoglucanase III target in Trichoderma reesei.
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Gunda SK, Narasimha SK, Shaik M: P56 (lck) kinase inhibitor studies: a 3D QSAR approach towards designing new drugs from flavonoid derivatives. Int J Comput Biol Drug Des. 2014; 7: 278-294.
Tripos, Sybyl 6.7, Tripos Inc., 1699 S. Hanley Rd., St. Louis, MO 63144
Chandrasekhar B and Bhima B: Cellulose as Sole Substrate for Bio Ethanol Production: Development of Structural Molecular Model of Endoglucanase III from Trichoderma Reesei Using Bioinformatic Tools. Int J Pharm Sci Res 2015; 6(3): 1132-36.doi: 10.13040/IJPSR.0975-8232.6(3).1132-36.
All © 2013 are reserved by International Journal of Pharmaceutical Sciences and Research. This Journal licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License.
Page No: 1132-1136
Authors: B. Chandrasekhar and B. Bhima*
Authors Address: Department of Microbiology, University College of Science, Osmania University, Hyderabad, India
Email: bhima.ou@gmail.com
Received: 17 July, 2014
Revised: 26 September, 2014
Accepted: 16 November, 2014
Published: 01 March, 2015


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Depending on your hardware, the software may create the free WiFi hotspot in adhoc mode, which may prevent some phones from connecting. Wrapping things up Wireless Hosted Network is a nifty feature in Windows can be a great tool to have for when you need to create a wireless access point on the go. If you intend to create a wireless network using your computer's wireless adapter, you'll need to be connected to the network via Ethernet. This is a free feature in service pack 1. Iomega's fourth generation StorCenter Network Hard Drive brings many of the features found in higher-end storage devices down to an attractive price.
This compensation may impact how and where products appear on this site including, for example, the order in which they appear. He is also the author of many networking and computing books, for brands such as For Dummies and Cisco Press. Sometimes publishers take a little while to make this information available, so please check back in a few days to see if it has been updated. If you're connected over Ethernet, choose the Ethernet connection. Manage the connecting devices:Rename it, Black it, Release it, Limit the Network Speed. With Maryfi, users can wirelessly share any Internet connection such as: a cable modem, a cellular card, or even another Wi-Fi network.
Click on the icon, and you can choose which network to connect to. Just go to homepage and download the app and install it. Run the Internet Connection troubleshooter If the issue persists, try this: Method 2 : I suggest you to update network drivers and check if that helps. Sometimes publishers take a little while to make this information available, so please check back in a few days to see if it has been updated. It solves all issues related to connecting to the Internet or the home network via its unique.


Essential oils are used in perfumes, food flavorings, medicine, and. What works?. This conclusion reflects the evidence of the review and appears likely to be reliable.. If you're interested in the scientific methods behind systematic reviews, .
However, this is beginning to change as more scientific studies on essential oils are conducted around the world.Clinical studies are currently underway in .
Actual scientific evidence for essential oils in humans (as opposed to test tubes) is. Antimicrobial superhero oil: working to make you look good for date night.
This article is an unbiased guide that digs into research, science, and the. In this article, I am going to break down whether essential oils are actually. . There is plenty of evidence based information serving as proof that essential oils work at .
Once the oils are in the system, they remodulate themselves and work in a. The essential oils are found to be more beneficial when other aspects of life and diet. .. The results showed clear evidence that use of this plant led to a significant .
This interview is conducted by Dr.EricZ, Robert Pappas,PhD is the authority on the therapeutic grade. He tells.


ONCE IN A LIFETIME OPPORTUNITY! It is your moment to create your piece of Stone Harbor history on this landmark site. There is approximately 220 degree panoramic u	..
Nestled in the dunes of beautiful Stone Harbor, this beachfront home rests conveniently on the South side of 104th Street. Designed by Oliveri Architects and with un	..
Unique bayfront property! This incredible bayfront property is being offered for sale and awaits a new owner. Tucked inside the highly desirable and deep water Stone	..
AN EXCEPTIONAL HOME CHANGES EVERYTHING! Picture yourself immersed in spectacular ocean views in this exceptional, FULLY FURNISHED new home. Imagine entertaining ..
In collaboration with OSK Design Partners and Harbaugh Developers another masterful home is in the works for Stone Harbor's coveted South end beaches. This new ..
Brand new custom Bayfront home having amazing sunset and wetland views. Overlooking Stone Harbors south end Sanctuary bay. Blaine Steinman designed hand crafted by ..
Stunning home for the Stone Harbor enthusiast. Situated 2nd from the beach with beautiful ocean views and just 3 blocks from downtown, this location offers everythin	..
It's not very often the opportunity arises to own a 2nd from the beach South side of last street in Stone Harbor home with panoramic views of the ocean, bay and th	..
Special BEACHBLOCK Opportunity, 2nd from the Beach Stone Harbor Property! Custom designed and built home that features Ocean views from the 1st floor decks, tremendo	..
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A luxurious Craftsman home steps away from the Southern most Stone Harbor Beaches. In one of the most sought after areas of 7 Mile Island this New Construction is in	..
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This brand new home is currently under construction by Tom Welsh! Ideally located on a large 60 x 110 lot & only about a block to wide, uncrowded beaches! You mi	..
One of Stone Harbors most sought after beach block streets! 115th is very private and secluded surrounded by beautiful homes, all on oversized lots. This home 4th ..
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text:
I'll Be Damned: How My Young and Restless Life Led Me to America's #1 Daytime Drama (Hardcover)
By Eric Braeden
Three Minutes in Poland: Discovering a Lost World in a 1938 Family Film (Paperback)
By Glenn Kurtz
The Zookeeper's Wife: A War Story (Paperback)
By Diane Ackerman
Irena's Children: The Extraordinary Story of the Woman Who Saved 2,500 Children from the Warsaw Ghetto (Paperback)
By Tilar J. Mazzeo
The Just: How Six Unlikely Heroes Saved Thousands of Jews from the Holocaust (Hardcover)
By Jan Brokken, David McKay (Translator)
Doctors from Hell: The Horrific Account of Nazi Experiments on Humans (Hardcover)
By Vivien Spitz
In the Garden of Beasts: Love, Terror, and an American Family in Hitler's Berlin (Hardcover)
By Erik Larson
The Art of Resistance: My Four Years in the French Underground: A Memoir (Paperback)
By Justus Rosenberg
The Light of Days: The Untold Story of Women Resistance Fighters in Hitler's Ghettos (Large Print / Paperback)
By Judy Batalion
A Doorway to Heroism: A decorated German-Jewish Soldier who became an American Hero (Paperback)
By W. Jack Romberg
The Inextinguishable Symphony: A True Story of Music and Love in Nazi Germany (Paperback)
By Martin Goldsmith
Man's Search for Meaning (Large Print / Paperback)
By Viktor E. Frankl, Harold S. Kushner (Foreword by), William J. Winslade (Afterword by)


Medical Laboratory Technologists conduct sophisticated diagnostic tests on blood, body fluids and tissues to provide important information used in detecting illness and monitoring health. They enjoy rewarding careers where they use their skills to; measure chemical components in blood and body fluids, detect diseases in blood cells, perform blood typing and cross-matching for blood transfusion, detect and identify infections caused by bacteria and fungi, and prepare surgical and autopsy tissues for analysis. Medical Laboratory Technologists represent one of the largest groups of professionals in health care.
The final year of the program occurs inside the laboratories of partner hospitals and private institutions and is arranged by the College. Students are expected to finance clinical placement costs (tuition, travel, room and board). Start date and location for third year placement are determined by program and clinical site requirements.
Graduates are eligible to write the general certificate exams of the Canadian Society for Medical Laboratory Science.
Click here to read the Quick Facts for prospective students interested in the MLS program, written with input from current students!
Medical Laboratory Science offers exciting opportunities for those who want a career in science and health care. Graduates find job opportunities in hospital laboratories, private laboratories, and public health institutions. Additional opportunities exist in research laboratories, clinics, business and industry. The profession also provides opportunities for specialization and leadership roles.
Students are responsible for the costs of immunizations and CPR/First Aid Training. Students are responsible for all expenses associated with clinical placement. Graduates of the program wishing to work in Canada as a certified medical laboratory technologist must successfully complete the Canadian Society for Medical Laboratory Science (CSMLS) national certification exam. Students are responsible for the arrangement and cost of this exam. As well, students wishing to work in Ontario as a registered medical laboratory technologist (MLT) must also apply for registration as a member of the College of Medical Laboratory Technologists of Ontario (CMLTO). Graduates are responsible for the cost of registration.
Minimum CPR Level BLS (Basic Life Saving) & Standard First Aid training up to date for placement – Semester 5. Students are responsible for arranging and paying for this.
Students must be able to demonstrate effective written and verbal communication skills.
Successful students have an strong aptitude for biological sciences, strong organizational and time management skills and pay attention to detail.
Criminal Background Check: Applicants are advised that Criminal Background Checks (CBC) and Vulnerable Sector Checks conducted by the Canadian Police Information Centre (CPIC) are required for clinical placement. Certain criminal convictions may prevent participation in placements and program completion. Applicants with criminal records must advise the Associate Dean/ Campus Dean and/or the Coordinator of the respective school prior to applying to the program or upon receiving the charge during the school term as applicable.
With experienced faculty who are very knowledgeable in their field and a very well organized program, Medical Laboratory Science at St. Lawrence College has done an outstanding job at preparing me for the national certification exam and to be able to work right away upon completion of the program.
Students from health sciences program on placement are covered by Workplace Safety and Insurance Board (WSIB) coverage in the event of an incident.
Due to the programs over-subscribed status applicants should check with the program coordinator prior to application to ascertain the availability of Advanced Standing seats. Applications must be accompanied by official transcripts and course outlines containing details about competencies or course objectives, course hours and assessment.


AstroDance dancers use stretch bands to represent the gravitational waves from supernovae.
Sai Pathmanathan is a science education consultant in the United Kingdom. She contributed this article to Live Science's Expert Voices: Op-Ed & Insights.
Bringing astrophysics to the masses is difficult at the best of times, but how do you communicate such complex science to students in underserved groups, such as those who are deaf or hard-of-hearing?
One research team has developed a unique approach: Use dance and stunning backdrops to teach the mathematics and physics of merging black holes. Manuela Campanelli, is director of the Center for Computational Relativity and Gravitation (CCRG) at the Rochester Institute of Technology (RIT) where she and her colleagues study how black holes merge. Through a grant from the U.S. National Science Foundation (NSF), Campanelli and her team have built an astrophysics and dance public engagement program, AstroDance, around their original research and a smaller, but popular, demonstration they presented during the Light in Winter Festival in Ithaca, N.Y.
The AstroDance dancers' movements represent the birth and evolution of the universe. This relates to recent discoveries that are bringing society closer to understanding what happened soon after the Big Bang.
In their research, Campanelli and her team use computer simulations to study the merging of super massive black holes. Such studies require processing several petabytes (one thousand million million bytes — 1,000,000,000,000,000 bytes) of information at once, a technical threshold that scientists once thought unobtainable, or at least many years away. However, thanks to the super computers NewHorizons, BlueSky, Stampede and Blue Waters, the RIT team is able to calculate theoretical simulations of black hole mergers where the masses of the merging black holes can vary by powers of ten. This will help researchers better understand the role of black hole mergers and related events within the universe, and what this could mean for the future of galaxies, like our own galaxy, the Milky-Way.
The question of how to communicate the research became obvious to Campanelli and her team: Since such science is about material bodies, gravitational pull and motion, why not use the grace of dance and spectacular imagery to captivate audiences?
Dance, like black holes, is about time and space, and provides a universal language to help represent complex concepts. Visuals and nonverbal, aesthetic, emotional experiences are important when engaging the deaf and hard-of-hearing, but yet are appealing to all, offering a different perspective to the communication and understanding of astrophysics research.
Using hoops, AstroDance dancers present an abstract representation of Black Holes merging.
Through AstroDance, performers reveal the nature of black holes, where time and space end, and from which nothing, not even light, can escape. Black holes convey tremendous visual depth, warping spacetime with their massand sending gravitational waves — ripples in spacetime — across the universe.
Over the next year, the AstroDance team will combine video clips of their live performanceswith scientist and artist interviews to produce a short educationaldocumentary film for further dissemination to the general public. The project will also gather data to evaluate the impact of dance on engaging audiences with STEM (science, technology, engineering and math) content.
A visual representation of space-time and other astrophysical concepts expressed by AstroDance dancers.
Dancing about complex science and astronomy themes is not new. Dance Your PhD is a competition designed to get early stage scientists communicating their research to the general public through dance and music, and Bethany Cobb, an NSF-funded postdoctoral fellow, brings awareness of the cosmos to the wider population through The Star Dances.
What makes AstroDance so innovative is that as a theatrical, dance and multimedia performance, it tells the story of the search for gravitational waves, presents public engagement alongside striking visualizations of black holes, and is genuinely for everyone: deaf, hard-of-hearing and hearing audiences.
A group photo of the AstroDance team showing the key vocabulary used throughout the show.
For more about AstroDance at the Rochester Institute of Technology.
Author's note: Dr. Campanelli would like to thank the whole team for the project's success: Antonietta Alfanso, Ashley Gast, Nicole Hood, Andrea Mariani, Leen Massillon, Carlos Valentin (dancers), Joseph Fox (narrator), Erin Auble, Hans-Peter Bischof, Joe Bochner, Jake Noel-Storr, Jason Nordhaus, Thomas Warfield and Yosef Zlochower (Rochester Institute of Technology).


The late princess didn't follow all of the royal dress rules.
Diana, Princess of Wales, abandoned aspects of royal dress etiquette to convey "approachability and warmth."
The late royal wanted the public to feel that she was a relatable figure that they could interact with easily—and used her wardrobe to relay that message.
"When she was visiting hospitals, for example, she would wear cheerful clothes that would convey warmth and often chunky jewellery so that children could come and play with them," Eleri Lynn, who has curated Kensington Palace's new exhibition, Diana: Her Fashion Story, told People.
She refused to wear gloves when conducting her royal duties—a royal tradition that historically denoted status, cleanliness, and purity.


Goodreads is having a giveaway for Dark Star Rising: Magick and Power in the Age of Trump, which will be released on May 29th. Five copies are up for grabs so get your skates on. And the Dark Star audio book – my first – is also available.
Hi Gary. You should maybe edit to explain that the giveaway is only valid for the US.
Thanks for that. I didn't know. My apologies for readers outside the US who were turned away.
Just got done reading your book Secret Teachers. Your survey of many writers and schools of thought seems quite comprehensive. Tell me if you've heard this one before:….
Imagine a species that evolves instead of a few tens of thousands of years, many millions of years. Eventually their brains grow so advanced they were able to transcend sequential time.
We live in sequential time in the material world. What would it mean to transcend sequential time? There would be no was or will be, there would only be is. In the material world the current moment continually unfolds into the next so quickly it can hardly be said that the immediate now even exists. But absent incessant sequential time, time would not exist there would only be is.
To transcend sequential time. To transcend three dimensional material existence. Is that what you might call the fourth dimension?
Imagine a species that has transcended three dimensional space and sequential time. Given the lack of fine wine and gourmet food while existing as pure energy, maybe, sometimes, for a vacation they decide to inhabit the bodies of material life forms just to experience the tactile pleasures. Maybe they exist like as a soul inside these alien bodies. And what more excellent a body to inhabit than the sexually obsessed war loving, semi intelligent humans on planet Earth?