text:
Marumbi  ist ein brasilianisches Munizip im Bundesstaat Paraná. Es hat 4676 Einwohner (2021), die sich Marumbienser nennen. Seine Fläche beträgt 208 km². Es liegt 673 Meter über dem Meeresspiegel.

Etymologie
Der Name stammt von einem Bach im Gebiet des Munizips, dem Rio Marumbi.

Geschichte

Besiedlung
Mitte 1942 wählte die Companhia de Terras Norte do Paraná (heute: Companhia Melhoramentos Norte do Paraná) die Stelle zur Schaffung eines Patrimônios. Die Fruchtbarkeit des Landes zog eine große Zahl von Menschen aus ganz Brasilien an.

Erhebung zum Munizip
Marumbi  wurde durch das Staatsgesetz Nr. 4245 vom 25. Juli 1960 in den Rang eines Munizips erhoben und am 14. November 1961 als Munizip installiert.

Geografie

Fläche und Lage
Marumbi  liegt auf dem Terceiro Planalto Paranaense (der Dritten oder Guarapuava-Hochebene von Paraná) auf 23° 42′ 21″ südlicher Breite und 51° 38′ 20″ westlicher Länge. Es hat eine Fläche von 208 km². Es liegt auf einer Höhe von 673 Metern.

Vegetation
Das Biom von Marumbi ist Mata Atlântica.

Klima
In Marumbi herrscht  gemäßigt warmes Klima. Die meiste Zeit im Jahr ist mit erheblichem Niederschlag zu rechnen. Selbst im trockensten Monat fällt eine Menge Regen. Die Klimaklassifikation nach Köppen und Geiger lautet Cfa. Es herrscht im Jahresdurchschnitt eine Temperatur von 21,2 °C. Innerhalb eines Jahres gibt es 1606 mm Niederschlag.

Gewässer
Marumbi liegt im Einzugsgebiet des Ivaí. Zu ihm fließen der Rio Bom entlang der östlichen und der Ribeirão Cambará entlang der westlichen Grenze des Munizips.

Straßen
Marumbi liegt abseits der großen Straßen. Über die PRT-466 erreicht man im Nordwesten die BR-369 nach Jandaia do Sul und im Süden Kaloré.

Nachbarmunizipien

Stadtverwaltung
Bürgermeister: Adhemar Francisco Rejani, PSD (2021–2024)

Vizebürgermeisterin: Elaine Maria Ferreira Costa (2021–2024)

Demografie

Bevölkerungsentwicklung

Quelle: IBGE (2011)

Ethnische Zusammensetzung

*) Das IBGE verwendet für Volkszählungen ausschließlich diese fünf Gruppen. Es verzichtet bewusst auf Erläuterungen. Die Zugehörigkeit wird vom Einwohner selbst festgelegt.

Quelle: IBGE (Stand: 1991, 2000 und 2010)

Wirtschaft
Das Munizip ist fast ausschließlich landwirtschaftlich geprägt.

Weblinks

 Website der Stadtpräfektur, Prefeitura Municipal (brasilianisches Portugiesisch)
 Atlas do Desenvolvimento no Brasil: Marumbi   (sozialstatistische Angaben, brasilianisches Portugiesisch)

Einzelnachweise

Ort in Paraná
Município in Paraná
Stadtrechtsverleihung 1961


text:
New crypto token started in Yellow Springs donates money to charity
By Eileen McClory, Staff Writer
Two Yellow Springs brothers — David and Brad Butcher — are the founders of a new crypto token that aims to give back.
It's uncommon for a crypto token to be founded outside of Silicon Valley. But the company has another unusual bent: profits from the tokens have so far been spent on giving away cars and donating to charity.
Since their launch on May 29, the organization says it has meted out nearly $200,000 to charity and given away about $600,000 worth of supercars to winners.
Their "Be Magical" fund is what a normal crypto would distribute to its founders. But since the Carma Coin team doesn't make money off the crypto, those funds go to charity and giving away supercars.
When you buy a crypto token, there's a 10% fee associated with it, and 3% of that is going to the "Be Magical" fund.
ExploreKettering Health to add surgery beds at Soin Medical Center
"It was just a way for us to give back," Brad Butcher said. "More than anything it was just a philanthropic idea."
Many people haven't believed they are giving away all the money that they are, he said.
"I think people are just suspicious at this point, although it's awesome to me," Brad Butcher said. "People are like, aren't you mad about that and like, no. What we're doing is so cool, it is literally unbelievable."
The Dayton Daily News confirmed with six of the eight charities Carma Coin donated to as of July that the donations were received. Carma Coin showed the Dayton Daily News receipts of the remaining two donations. The newspaper also spoke with three Americans, two who live in the greater Dayton region, who said they received supercars from the crypto company. Most of the remainder of the vehicles had yet to be handed off, Brad Butcher said.
ExploreWright State notifies some faculty of eliminated positions
Brad Butcher, who currently lives in Yellow Springs and grew up in Fairborn, said he and his brother David started investing in cryptocurrency a few years ago. They made some money off it, but also figured out many cryptocurrencies lose money.
The brothers decided they would try to make a coin that didn't make many of those same mistakes but had a philanthropic bent.
Scott Morin, the chief operating officer for Carma Coin, said it was more difficult for them to get into some crypto spaces because the three of them are not insiders. Even though the sales were breaking records, he said it was still more difficult for them to break in at the beginning.
ExploreCourt-martial of ex-AFRL commander scheduled at Wright-Patterson
"Now that we've accomplished a lot of those milestones, we're here, we're in the space," Morin said.
The token has been available since late May. Brad Butcher said he was surprised at how quickly it took off, but the team has high hopes for the long term. They were in talks with some restaurants to accept their crypto there and have plans to get car dealerships to accept the tokens, he said.
Brad Butcher said he believes crypto will become a more common currency over time.
"People want something new," he said.
David Butcher also owns Flyby BBQ in Beavercreek.
Why do gas stations with convenience stores love Ohio? Location
Ohio reports fewer than 10,000 COVID cases for 2nd straight week
Eileen McClory is the education reporter for the Dayton Daily News. She grew up in the Dayton area and returned to cover her hometown.

redpajama_set_name: RedPajamaCommonCrawl


text:
A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease
Mark A. Schroeder, H. Jean Khoury, Madan Jagasia, Haris Ali, Gary J. Schiller, Karl Staser, Jaebok Choi, Leah Gehrs, Michael C. Arbushites, Ying Yan, Peter Langmuir, Nithya Srinivas, Michael Pratta, Miguel Angel Perales, Yi Bin Chen, Gabrielle Meyers, John F. DiPersio
Hematology & Medical Oncology
Acute graft-versus-host disease (aGVHD) following allogeneic hematopoietic cell transplantation (HCT) is a primary cause of nonrelapse mortality and a major barrier to successful transplant outcomes. Itacitinib is a Janus kinase (JAK)1–selective inhibitor that has demonstrated efficacy in preclinical models of aGVHD. We report results from the first registered study of a JAK inhibitor in patients with aGVHD. This was an open-label phase 1 study enrolling patients aged $18 years with first HCT from any source who developed grade IIB to IVD aGVHD. Patients with steroid-naive or steroid-refractory aGVHD were randomized 1:1 to itacitinib 200 mg or 300 mg once daily plus corticosteroids. The primary endpoint was safety and tolerability; day 28 overall response rate (ORR) was the main secondary endpoint. Twenty-nine patients (200 mg, n 5 14; 300 mg, n 5 15) received $1 dose of itacitinib and were included in safety and efficacy assessments. One dose-limiting toxicity was reported (grade 3 thrombocytopenia attributed to GVHD progression in a patient receiving 300 mg itacitinib with preexisting thrombocytopenia). The most common nonhematologic treatment-emergent adverse event was diarrhea (48.3%, n 5 14); anemia occurred in 11 patients (38%). ORR on day 28 for all patients in the 200-mg and 300-mg groups was 78.6% and 66.7%, respectively. Day 28 ORR was 75.0% for patients with treatment-naive aGVHD and 70.6% in those with steroid-refractory aGVHD. All patients receiving itacitinib decreased corticosteroid use over time. In summary, itacitinib was well tolerated and demonstrated encouraging efficacy in patients with steroid-naive or steroid-refractory aGVHD, warranting continued clinical investigations. This trial was registered at www.clinicaltrials.gov as #NCT02614612.
https://doi.org/10.1182/bloodadvances.2019001043
Published - Apr 28 2020
Dive into the research topics of 'A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease'. Together they form a unique fingerprint.
Graft vs Host Disease Medicine & Life Sciences 100%
Steroids Medicine & Life Sciences 35%
Janus Kinase Inhibitors Medicine & Life Sciences 26%
Cell Transplantation Medicine & Life Sciences 20%
Thrombocytopenia Medicine & Life Sciences 17%
Safety Medicine & Life Sciences 11%
Allogeneic Cells Medicine & Life Sciences 10%
Schroeder, M. A., Jean Khoury, H., Jagasia, M., Ali, H., Schiller, G. J., Staser, K., Choi, J., Gehrs, L., Arbushites, M. C., Yan, Y., Langmuir, P., Srinivas, N., Pratta, M., Perales, M. A., Chen, Y. B., Meyers, G., & DiPersio, J. F. (2020). A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease. Blood Advances, 4(8), 1657-1669. https://doi.org/10.1182/bloodadvances.2019001043
A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease. / Schroeder, Mark A.; Jean Khoury, H.; Jagasia, Madan et al.
In: Blood Advances, Vol. 4, No. 8, 28.04.2020, p. 1657-1669.
Schroeder, MA, Jean Khoury, H, Jagasia, M, Ali, H, Schiller, GJ, Staser, K, Choi, J, Gehrs, L, Arbushites, MC, Yan, Y, Langmuir, P, Srinivas, N, Pratta, M, Perales, MA, Chen, YB, Meyers, G & DiPersio, JF 2020, 'A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease', Blood Advances, vol. 4, no. 8, pp. 1657-1669. https://doi.org/10.1182/bloodadvances.2019001043
Schroeder MA, Jean Khoury H, Jagasia M, Ali H, Schiller GJ, Staser K et al. A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease. Blood Advances. 2020 Apr 28;4(8):1657-1669. doi: 10.1182/bloodadvances.2019001043
Schroeder, Mark A. ; Jean Khoury, H. ; Jagasia, Madan et al. / A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease. In: Blood Advances. 2020 ; Vol. 4, No. 8. pp. 1657-1669.
@article{954f5ee0e47147d1bd2cdcf43f06dbae,
title = "A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease",
abstract = "Acute graft-versus-host disease (aGVHD) following allogeneic hematopoietic cell transplantation (HCT) is a primary cause of nonrelapse mortality and a major barrier to successful transplant outcomes. Itacitinib is a Janus kinase (JAK)1–selective inhibitor that has demonstrated efficacy in preclinical models of aGVHD. We report results from the first registered study of a JAK inhibitor in patients with aGVHD. This was an open-label phase 1 study enrolling patients aged $18 years with first HCT from any source who developed grade IIB to IVD aGVHD. Patients with steroid-naive or steroid-refractory aGVHD were randomized 1:1 to itacitinib 200 mg or 300 mg once daily plus corticosteroids. The primary endpoint was safety and tolerability; day 28 overall response rate (ORR) was the main secondary endpoint. Twenty-nine patients (200 mg, n 5 14; 300 mg, n 5 15) received $1 dose of itacitinib and were included in safety and efficacy assessments. One dose-limiting toxicity was reported (grade 3 thrombocytopenia attributed to GVHD progression in a patient receiving 300 mg itacitinib with preexisting thrombocytopenia). The most common nonhematologic treatment-emergent adverse event was diarrhea (48.3%, n 5 14); anemia occurred in 11 patients (38%). ORR on day 28 for all patients in the 200-mg and 300-mg groups was 78.6% and 66.7%, respectively. Day 28 ORR was 75.0% for patients with treatment-naive aGVHD and 70.6% in those with steroid-refractory aGVHD. All patients receiving itacitinib decreased corticosteroid use over time. In summary, itacitinib was well tolerated and demonstrated encouraging efficacy in patients with steroid-naive or steroid-refractory aGVHD, warranting continued clinical investigations. This trial was registered at www.clinicaltrials.gov as #NCT02614612.",
author = "Schroeder, {Mark A.} and {Jean Khoury}, H. and Madan Jagasia and Haris Ali and Schiller, {Gary J.} and Karl Staser and Jaebok Choi and Leah Gehrs and Arbushites, {Michael C.} and Ying Yan and Peter Langmuir and Nithya Srinivas and Michael Pratta and Perales, {Miguel Angel} and Chen, {Yi Bin} and Gabrielle Meyers and DiPersio, {John F.}",
note = "Funding Information: This study was funded by Incyte Corporation and received support from National Institutes of Health, National Cancer Institute grants P30-CA9184201 (J.F.D.), SPORE P50-CA171963-01 (J.F.D.), R35 1R35-CA210084 (J.F.D.), the Amy Strelzer Manasevit Research Program (Be The Match Foundation and the National Marrow Donor Program) (J.C.), and the Alvin J. Siteman Cancer Center Siteman Investment Program (Foundation for Barnes-Jewish Hospital Cancer Frontier Fund, National Cancer Institute Cancer Center Support Grant, P30 CA091842, and Barnard Trust) (J.C.). Funding Information: Conflict-of-interest disclosure: M.A.S. received honoraria and research funding from Incyte Corporation. H.J.K. served on an advisory board and received research funding from Incyte Corporation. M.J. received research funding from Therakos, Janssen, and Incyte Corporation. H.A. and G.J.S. received research funding from Incyte Corporation. K.S. served as a consultant for RiverVest and Kinetic River and is a coinventor on a patent related to CART therapy. J.C. received honorarium from Incyte Corporation, received research funding from Mallinckrodt Pharmaceuticals, and served as a consultant for Daewoong Pharmaceutical. M.C.A., Y.Y., P.L., N.S., and M.P. are employees and stockholders of Incyte Corporation. M.-A.P. received honoraria from AbbVie, Bellicum, Bristol-Myers Squibb, Incyte Corporation, Merck, Novartis, Nektar Therapeutics, Omeros, and Takeda; served on data and safety monitoring boards for Servier and Medigene; served on scientific advisory boards for MolMed and NexImmune; and has received research support for clinical trials from Incyte Corporation, Kite/Gilead, and Miltenyl Biotec. Y.-B.C. served as a consultant for Incyte Corporation and Takeda and received research funding from Incyte Corporation and Novartis Pharmaceuticals. J.F.D. served on advisory boards for Incyte Corporation, CellWorks, Macrogenics, Amphivena, Arch, Rivervest, and Bioline and is a cofounder of Magenta Therapeutics and WUGen. The remaining authors declare no competing financial interests. Publisher Copyright: {\textcopyright} 2020 by The American Society of Hematology",
doi = "10.1182/bloodadvances.2019001043",
journal = "Blood advances",
publisher = "American Society of Hematology",
T1 - A phase 1 trial of itacitinib, a selective JAK1 inhibitor, in patients with acute graft-versus-host disease
AU - Schroeder, Mark A.
AU - Jean Khoury, H.
AU - Jagasia, Madan
AU - Ali, Haris
AU - Schiller, Gary J.
AU - Staser, Karl
AU - Choi, Jaebok
AU - Gehrs, Leah
AU - Arbushites, Michael C.
AU - Yan, Ying
AU - Langmuir, Peter
AU - Srinivas, Nithya
AU - Pratta, Michael
AU - Perales, Miguel Angel
AU - Chen, Yi Bin
AU - Meyers, Gabrielle
AU - DiPersio, John F.
N1 - Funding Information: This study was funded by Incyte Corporation and received support from National Institutes of Health, National Cancer Institute grants P30-CA9184201 (J.F.D.), SPORE P50-CA171963-01 (J.F.D.), R35 1R35-CA210084 (J.F.D.), the Amy Strelzer Manasevit Research Program (Be The Match Foundation and the National Marrow Donor Program) (J.C.), and the Alvin J. Siteman Cancer Center Siteman Investment Program (Foundation for Barnes-Jewish Hospital Cancer Frontier Fund, National Cancer Institute Cancer Center Support Grant, P30 CA091842, and Barnard Trust) (J.C.). Funding Information: Conflict-of-interest disclosure: M.A.S. received honoraria and research funding from Incyte Corporation. H.J.K. served on an advisory board and received research funding from Incyte Corporation. M.J. received research funding from Therakos, Janssen, and Incyte Corporation. H.A. and G.J.S. received research funding from Incyte Corporation. K.S. served as a consultant for RiverVest and Kinetic River and is a coinventor on a patent related to CART therapy. J.C. received honorarium from Incyte Corporation, received research funding from Mallinckrodt Pharmaceuticals, and served as a consultant for Daewoong Pharmaceutical. M.C.A., Y.Y., P.L., N.S., and M.P. are employees and stockholders of Incyte Corporation. M.-A.P. received honoraria from AbbVie, Bellicum, Bristol-Myers Squibb, Incyte Corporation, Merck, Novartis, Nektar Therapeutics, Omeros, and Takeda; served on data and safety monitoring boards for Servier and Medigene; served on scientific advisory boards for MolMed and NexImmune; and has received research support for clinical trials from Incyte Corporation, Kite/Gilead, and Miltenyl Biotec. Y.-B.C. served as a consultant for Incyte Corporation and Takeda and received research funding from Incyte Corporation and Novartis Pharmaceuticals. J.F.D. served on advisory boards for Incyte Corporation, CellWorks, Macrogenics, Amphivena, Arch, Rivervest, and Bioline and is a cofounder of Magenta Therapeutics and WUGen. The remaining authors declare no competing financial interests. Publisher Copyright: © 2020 by The American Society of Hematology
N2 - Acute graft-versus-host disease (aGVHD) following allogeneic hematopoietic cell transplantation (HCT) is a primary cause of nonrelapse mortality and a major barrier to successful transplant outcomes. Itacitinib is a Janus kinase (JAK)1–selective inhibitor that has demonstrated efficacy in preclinical models of aGVHD. We report results from the first registered study of a JAK inhibitor in patients with aGVHD. This was an open-label phase 1 study enrolling patients aged $18 years with first HCT from any source who developed grade IIB to IVD aGVHD. Patients with steroid-naive or steroid-refractory aGVHD were randomized 1:1 to itacitinib 200 mg or 300 mg once daily plus corticosteroids. The primary endpoint was safety and tolerability; day 28 overall response rate (ORR) was the main secondary endpoint. Twenty-nine patients (200 mg, n 5 14; 300 mg, n 5 15) received $1 dose of itacitinib and were included in safety and efficacy assessments. One dose-limiting toxicity was reported (grade 3 thrombocytopenia attributed to GVHD progression in a patient receiving 300 mg itacitinib with preexisting thrombocytopenia). The most common nonhematologic treatment-emergent adverse event was diarrhea (48.3%, n 5 14); anemia occurred in 11 patients (38%). ORR on day 28 for all patients in the 200-mg and 300-mg groups was 78.6% and 66.7%, respectively. Day 28 ORR was 75.0% for patients with treatment-naive aGVHD and 70.6% in those with steroid-refractory aGVHD. All patients receiving itacitinib decreased corticosteroid use over time. In summary, itacitinib was well tolerated and demonstrated encouraging efficacy in patients with steroid-naive or steroid-refractory aGVHD, warranting continued clinical investigations. This trial was registered at www.clinicaltrials.gov as #NCT02614612.
AB - Acute graft-versus-host disease (aGVHD) following allogeneic hematopoietic cell transplantation (HCT) is a primary cause of nonrelapse mortality and a major barrier to successful transplant outcomes. Itacitinib is a Janus kinase (JAK)1–selective inhibitor that has demonstrated efficacy in preclinical models of aGVHD. We report results from the first registered study of a JAK inhibitor in patients with aGVHD. This was an open-label phase 1 study enrolling patients aged $18 years with first HCT from any source who developed grade IIB to IVD aGVHD. Patients with steroid-naive or steroid-refractory aGVHD were randomized 1:1 to itacitinib 200 mg or 300 mg once daily plus corticosteroids. The primary endpoint was safety and tolerability; day 28 overall response rate (ORR) was the main secondary endpoint. Twenty-nine patients (200 mg, n 5 14; 300 mg, n 5 15) received $1 dose of itacitinib and were included in safety and efficacy assessments. One dose-limiting toxicity was reported (grade 3 thrombocytopenia attributed to GVHD progression in a patient receiving 300 mg itacitinib with preexisting thrombocytopenia). The most common nonhematologic treatment-emergent adverse event was diarrhea (48.3%, n 5 14); anemia occurred in 11 patients (38%). ORR on day 28 for all patients in the 200-mg and 300-mg groups was 78.6% and 66.7%, respectively. Day 28 ORR was 75.0% for patients with treatment-naive aGVHD and 70.6% in those with steroid-refractory aGVHD. All patients receiving itacitinib decreased corticosteroid use over time. In summary, itacitinib was well tolerated and demonstrated encouraging efficacy in patients with steroid-naive or steroid-refractory aGVHD, warranting continued clinical investigations. This trial was registered at www.clinicaltrials.gov as #NCT02614612.
U2 - 10.1182/bloodadvances.2019001043
DO - 10.1182/bloodadvances.2019001043
JO - Blood advances
JF - Blood advances


The NAEYC blog aims to increase general awareness and engage the public in thoughtful discussion around topics and themes related to early childhood education. We share NAEYC initiatives and explore what's new, upcoming, timely, or topical in the early childhood field.
We have expanded the focus of the blog to also include content that families might find useful. Tip: to view blog posts intended for families only, use the "Refine" box to the right and select "For Families Blog".
On April 21, NAEYC, along with many other educational organizations, researchers and thought leaders, helped kick off a White House Early Learning STEM initiative!
Join us on a trip ten years into the future, to May 1, 2026…Today, we celebrate the 10th anniversary of the year that the tide began to turn for early childhood education — and early childhood educators.
You taught me and I taught you. We were companions and while you may have forgotten me, I will never forget you!
The settings in which children practice new skills work best when the environment reflects the individual child, family, and community.
Words matter, but so does what's behind the words. Let's take away the magic of "the magic word," and start teaching kids politeness.
Here are some ways I've used books for play with children. You can try these or come up with your own.
Longtime NAEYC member and prominent advocate for the importance of play to children's learning, Bev Bos, passed away on February 4, 2016.
As parents, taking into account how different our children's minds are from our own helps us check our expectations.
It allowed me to really appreciate the "team behind my teacher" when we attended a parent–teacher conference that included so many support staff and teachers, including an occupational therapist, speech therapist, and special education teacher.


text:
08/22/2018 ARRivera
Actually, this next section of the book I'm about to share is from the fourth chapter. That's because as I have been writing this book, I realized that my main character has yet to be introduced, and shame on me for waiting so long!
The rules of writing dictate that the story's MC be introduced as soon as possible, and the main plot should open by chapter three. But this story is my first narrative that isn't told from a first-person perspective. It's also controversial in nature, and I think that's been throwing me.
That's enough about me. On with the story!
(Add it to your Wattpad library and get updates)
Miss Gravez
"Did Mr. Marcel come back yet?" Her question fell into the void of the nearly empty study area cut off from the rest of the library by a wall of foggy windows that marked the entry into the study rooms at the far end of the building.
The regular librarian, Lucy Vargas, was out. Jordan Marcel was filling in while she was on maternity leave. Mr. Marcel was a good substitute when you could find him.
Three more weeks until we get Lucy back, Lexi Gravez told herself, adjusting the chain of her charm necklace.
Ana-Lucia, the only student in first-hour study hall that morning, looked up from her work and shook her head, rotating one shoulder at the same time. Lexi couldn't decide what this mixed gesture meant but didn't bother with a follow-up.
She left the partitioned space and marched up-front to the circulation desk. Snatching a sticky note from the dwindling tablet Mr. Marcel kept in front of his computer, she wrote in neat script, 'Please order a copy of 'The Portable Henry Rollins.'
She'd always been a nosey-fart, was always picking up bits of conversations as she passed students in the halls. So when Miss Gravez heard Eric Halyan, a junior, saying how quotable the book was, it caught her attention.
Eric had never been much of a talker. As she passed him and his two friends on her way to the library, she made a mental note to check it out. But the school library didn't have any copies. If there was a book out there that could make an introvert like Eric talk—make him want to quote—then she wanted to give it a read.
As a teacher, she knew that kids didn't speak-up if they thought no one would listen, but they also bared their souls when they thought no one could hear.
Turning on her heel, she headed back towards the tutoring center. Mr. Marcel would be back eventually and she could check-in with him then.
Eric Halyan had always presented a sort of enigma to Miss Marquez. He was popular, but still on the fringes. Well-liked, as far as she could tell. He also drove a nicer car than she did. His parents seemed like good people, even if his father was sterner than she liked. Maybe that's because she'd only run into him at football games. He was at the Rattlesnakes stadium every Friday night, even though Eric was not involved in sports. If she had to give him one of those trite High School labels, like in the movies, Lexi might say Eric was a 'theatre rat.'
He only hung around with two people: Russell Simms and Peter Warren. Both were with him in the hall when she passed ten minutes ago. Eric was painfully shy. He never spoke up in class. Not even when directly addressed.
Once, when Miss Gravez was subbing for Nelson—Mr. Nelson—in AP English, she'd called on him. Eric just sat there, looking between her and the doodles on his worksheet.
She moved on quickly, but he'd made her feel like a jerk.
Once back at her desk in the tutoring center, she logged onto the computer and started searching Goodreads for information on the book. A page of quotes came up, Lexi skimmed them and picked one she particularly liked:
"It hurts to let go. Sometimes it seems the harder you try to hold on to something or someone the more it wants to get away."
The Henry Rollins Lexi Gravez was familiar with was the eccentric frontman of Black Flag—an angry performance artist and radical theorist. He can write, too, Lexi mused.
She was deep into the third page when the kerplunk of falling objects tore her attention from the computer screen.
A heap of books splattered to the floor near table three, beneath Ana-Lucia, the only student that bothered to show for Study Hall that morning.
She'd spilled her coffee, which was not allowed in the library in the first place, but Miss Gravez looked the other way because she was addicted to the stuff and hated hypocrites. As far as she was concerned Coffee would always be allowed, everywhere. Ana had knocked her homework to the floor to keep it from getting wet.
The word "Chihuahua," was muttered like a curse under her breath as Miss Gravez hustled to the staff bathroom. It was at the end of a short hall about ten feet behind her desk. She used a key from the ring around her wrist to unlock the door. Inside, there was a tall cabinet where extra toiletries were kept. She grabbed a bundle of paper towels and sprinted back out.
The study area was wrapped in warm vanilla and sugar scented greatness. Everything would get sticky.
Going low to catch the stream dribbling onto the carpet, Lexi—Miss Gravez—tossed Ana-Lucia Campos part of the wad of towels so she could get to work up top.
That's when the banging started.
Bang-bang-bang-
Lexi's first thought was that of a car backfiring. No … maybe construction workers out on the street? They didn't get those kinds of sounds back in the library. They were nowhere near the parking area or the road. The building was a four-story tower smack in the middle of campus.
-Bang-Bang-Bang- Like a beating drum that warned of coming danger.
There were screams mingled with panicked sounds.
"What was that?" Ana straightened.
Lexi, always one to keep a clear head in stressful situations, pulled on Ana Lucia's pant leg, dragging her under the table as more warnings sounded off. More bangs and pops.
"What is that?" Ana-Lucia's eyes were round, like a lost, scared puppy.
Lexi didn't need to say it—couldn't even if she tried. "Shh," pressing a hand to the student's chin, Lexi shook her head in the universal 'shut it' gesture.
Lexi's mother's side of the family were all cops and fireman. Her mom was the odd-man-out, so to speak since she was the only girl and a Registered Nurse. Emergency prep felt like part of her bloodline.
Pop-pop-pop-pop-pop…
Before the fear took over, Lexi took a deep breath and detached herself from it. It was still there, plain as day, but she put a cap on it by pondering the answer to Ana-Lucia's question. Forcing herself to think about the answer and their circumstances as separate, as if one had nothing to do with the other.
It sounded a lot like gunshots, Lexi had to admit. Not the first time I've heard them, she recalled, and then fear lashed out, grabbing her by the throat.
Think-think!
Slapping her cheek made her mouth work. "Ana."
Ana-Lucia wasn't looking at Miss Gravez anymore. Her eyes were on the foggy glass wall. Lexi looked there, too.
Long shapes moved along the other side. They couldn't tell male from female, cop from criminal; saint from sinner. The gauzy glass deformed everything and there was no way to know just how far or close the shapes were to them.
Columbine, Lexi thought the name over and over through the noise blaring through the library. It was a long room with dozens of tall bookshelves in nice, neat rows. But it didn't matter if the noises originated from the front of the library or just beyond the glass wall. They were gunshots and they were too close.
Grabbing Ana's chin again, Miss Gravez forced her to pay attention. "Ana-Lucia, follow me."
"What wa-as that?"
"Pay attention. Look only at me. We are going to crawl behind this row of tables, down the hall, to the bathroom. You're going to follow me. Okay?"
So we don't die.
"To hide."
Ana's whole body was shaking. Her eyes were glossed, giving a blank gaze. There was nothing behind it, nothing but sheer panic.
Deadly panic.
Keep your head, so you keep your head, the family saying trickled through Lexi's mind as another series of cries broke out from beyond the glass barrier. They mingled with loud crashes and a giant boom that shook the walls and floor. Their bones. It sounded like World War III had broken out in the library.
The curl of a low-pitched laugh unraveled them both.
Lexi's hand covered Ana's mouth just as a dark puddle at the crotch of the girls' pants appeared and grew.
A sob caught in Lexi's throat. She swallowed and wiped a tear from Ana's cheek. "Let's go."
Lexi led the way between two chairs to the other side of the table. As soon as they cleared the edge, she felt naked and exposed. She wanted to stop and hunker down but kept crawling.
Hurry.
An odd wail ripped through the library—it sounded like a man.
Go faster.
On all fours, crawling, Lexi felt Ana's breath on her leg and encouraged with a whisper, "Hurry, Ana," as they turned between the side wall and a short row of reference books.
Then … something set Ana off. She released a howl; high-pitched and blood-curdling. By instinct, Lexi reared back, slapped her hand over Ana's mouth and whispered in her ear. The intention was to soothe, but that's not how it came out.
"You're going to get us killed—"
Ana bit the flesh crossing her lips and broke free, running in a half-crouch back to the table, shouting, "my phone!"
A feeling like glue stuck Lexi to that little stitch of carpet between the back wall and the bookshelf. Every muscle in her body tensed, watching Ana.
Inside Lexi was screaming, "Get down!" But it came out low, barely audible over the racket coming from the other side of the clouded glass.
What the hell was going on over there? How long had it been? Where was campus Security? Where was Officer Leeland?
Ana grabbed her cell phone and Lexi let out a breath as Ana turned her direction. But instead of staying crouched, the girl stood up. Then in that same moment, she fell backward. Cell phone in-hand, Ana-Lucia toppled like a great tower, quick and unnatural.
Lexi's vision tunneled. Her heart was beating so loud, that when the glass partition shattered into a million pieces, she didn't hear it. Couldn't see it. She felt a thousand needle-pricks all at once, mostly about her head and face, and released the fear she'd been holding back in a scream.
I'll post another section next week, but if you can't wait, most of my work is available on Wattpad and Smashwords
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More heavy stuff. I like it.


Who should our agency appoint as PCO?
What do I need to know as a PCO?
PCOs are the first point of contact for advice on privacy matters related to their agency. The Office of the Australian Information Commissioner (OAIC) strongly encourages each agency to have a PCO.
The OAIC coordinates a network of government privacy and freedom of information contact officers called the Information Contact Officers Network (ICON). If you are a PCO and would like to join ICON, further information is available on the Subscribe page of this website.
You can also contact us to find out who your agency PCO is, or to find out the PCO of another agency.
Make sure you appoint someone of sufficient seniority to be PCO. Generally, an officer below the executive level would have difficulty fulfilling the role. This is because the PCO needs to be involved in many aspects of the agency's operations, including the decision-making processes of the agency.
being the primary privacy contact for the Office of the Australian Information Commissioner.
As a PCO, you need to have a good understanding of the Australian Privacy Principles (APPs) in the Privacy Act. Understanding the APPs will help you provide internal advice on the application of the Privacy Act to your agency's activities and to assess privacy complaints made by individuals.
There is plenty of guidance material to help you in your role as PCO. Take a look at the Privacy topics — Government section and the Privacy resources.
You should also try to attend ICON meetings to keep abreast of new developments and helpful documents associated with privacy.
In the event that a data breach occurs in your agency, depending on the severity of the breach, it can be a good idea to inform our office.
The OAIC updated its detailed guidance about Data Breach Notification in April 2012. Please see Data breach notification - A guide to handling personal information security breaches.
The Office of the Australian Information Commissioner (OAIC) responds, where possible, to agency requests for advice on matters with significant privacy implications. The OAIC expects to be consulted on any agency proposals involving the handling of personal information that might have a significant impact on the privacy of individuals, including: notable new policy proposals or changes to existing activities, cabinet submissions and pieces of draft legislation.
Privacy issues related to national security initiatives.
We encourage agencies and their privacy contact officers (PCOs) to make use of the generic advice available in the Australian Privacy Principles (APP) Guidelines, and other information provided on our website. We also encourage PCOs to use the Information Contact Officers Network, which serves as an invaluable source of collective experience and learning in relation to Australian public sector privacy and freedom of information.


Improve your customer's experience by showing the appropriate State/County/Province when the Country field is changed.
If the selected country does not have any regions in the database, replace the dropdown with a text field.
Comes out of the box with US and Brazilian States, and Canadian Provinces. Additional countries/regions can be found here.
For best results, use with eShop Shipping Extension.
Alternate State field is removed, as it is no longer necessary. If a user selects a country for which there are States/Counties/Provinces in the database, then a drop-down is presented.
If no data exists in the database, then a text input field is presented to the user instead.
Where can I get additional countries/regions?
Additional countries/regions can be found here.
"eShop Checkout Dynamic States" is open source software. The following people have contributed to this plugin.
Translate "eShop Checkout Dynamic States" into your language.
Fixed typo in previous commit which messed up shipping states.
Making sure that the session is started.
Saving state/shipstate state with $.totalStorage. Clicking the back button no longer forces the user to re-select the state.
Removed FK name of states table due to possible naming conflicts.
Modified primary key of states table as it was failing to add a few states.
Maintaining state when a user submits the checkout form with missing required fields.


text:
PLoS Genet. 2009 Mar;5(3):e1000438. doi: 10.1371/journal.pgen.1000438. Epub 2009 Mar 27.
DNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolution.
Zhang Y1, Rohde C, Tierling S, Jurkowski TP, Bock C, Santacruz D, Ragozin S, Reinhardt R, Groth M, Walter J, Jeltsch A.
School of Engineering and Science, Jacobs University Bremen, Bremen, Germany.
Differential DNA methylation is an essential epigenetic signal for gene regulation, development, and disease processes. We mapped DNA methylation patterns of 190 gene promoter regions on chromosome 21 using bisulfite conversion and subclone sequencing in five human cell types. A total of 28,626 subclones were sequenced at high accuracy using (long-read) Sanger sequencing resulting in the measurement of the DNA methylation state of 580427 CpG sites. Our results show that average DNA methylation levels are distributed bimodally with enrichment of highly methylated and unmethylated sequences, both for amplicons and individual subclones, which represent single alleles from individual cells. Within CpG-rich sequences, DNA methylation was found to be anti-correlated with CpG dinucleotide density and GC content, and methylated CpGs are more likely to be flanked by AT-rich sequences. We observed over-representation of CpG sites in distances of 9, 18, and 27 bps in highly methylated amplicons. However, DNA sequence alone is not sufficient to predict an amplicon's DNA methylation status, since 43% of all amplicons are differentially methylated between the cell types studied here. DNA methylation in promoter regions is strongly correlated with the absence of gene expression and low levels of activating epigenetic marks like H3K4 methylation and H3K9 and K14 acetylation. Utilizing the single base pair and single allele resolution of our data, we found that i) amplicons from different parts of a CpG island frequently differ in their DNA methylation level, ii) methylation levels of individual cells in one tissue are very similar, and iii) methylation patterns follow a relaxed site-specific distribution. Furthermore, iv) we identified three cases of allele-specific DNA methylation on chromosome 21. Our data shed new light on the nature of methylation patterns in human cells, the sequence dependence of DNA methylation, and its function as epigenetic signal in gene regulation. Further, we illustrate genotype-epigenotype interactions by showing novel examples of allele-specific methylation.
10.1371/journal.pgen.1000438
Summary of the DNA methylation data.
(A) Clustered heatmap of the DNA methylation levels of all amplicons studied in HEK293, HepG2, leukocytes, fibroblast, and trisomic fibroblast cells, ordered by the average level of DNA methylation and similarity across tissues. (B) DNA methylation levels of selected highly methylated amplicons in HEK293 after treatment of the cell line with 5-azacytidine (for detail, see ). (C) Tissue similarity plot comparing the methylation patterns of all five cell types studied here. The numbers represent pair wise Pearson correlation coefficients between each pair of cell types, calculated using the average DNA methylation levels for all amplicons. (D) Bimodal distribution of the DNA methylation level of all amplicons, clones, and CpG sites.
DNA Methylation Analysis of Chromosome 21 Gene Promoters at Single Base Pair and Single Allele Resolution
PLoS Genet. 2009 Mar;5(3):e1000438.
Analysis of DNA methylation patterns of amplicons.
(A) Average methylation levels of clones were extracted and compared with the average methylation level of the corresponding PCR product. (B) Extreme types of possible patterns of DNA methylation being either distributed in a site-specific manner or stochastically. (C) Average methylation levels of all CpG sites from all PCR products were compared with the average methylation level of the respective PCR products, indicating that methylation levels of sites are not stochastically distributed. (D) The methylation patterns of all CpG sites were extracted and for each site the probability of the observed pattern calculated assuming a model of stochastic distribution. The distribution was plotted indicating a significant enrichment of sites with unexpected methylation pattern.
Example of amplicons located on the same CpG island but showing different DNA methylation levels and decreasing methylation when approaching the TSS of the gene.
The figure shows the position of these amplicons in the UCSC genome browser in the lower part and it schematically displays the methylation pattern of five amplicons determined in HEK293 in the upper part. Each row corresponds to one sequenced clone of the bisulfite PCR product. Each column corresponds to one CpG site. The color code indicates the methylation state of the individual CpG site in each clone.
Correlation of DNA methylation and DNA sequence properties.
(A) Association of DNA methylation with low CpG density and GC content. (B) Overrepresentation of distances between CpG sites in the sequences of highly methylated DNA as compared to low methylated. The occurrences of all distances of CpG sites were counted in highly methylated (HM) amplicons and low methylated (LM) amplicons. Then, the ratio of both numbers (HM/LM) was plotted versus the distance in bps (shown in black). The same calculation was performed 12 times with randomized methylation level of all amplicons (shown in light gray). The simulations were used to derive the p-value of the overrepresentation of the peaks at 9 bps (p-value <2.0×10−5), 18 bps (p-value <1.5×10−8) and 27 bps (p-value <1.1×10−4).
Over- and under-representation of bases in the flanks of methylated CpG sites using different threshold of DNA methylation (≥90%, ≥80%, ≥70%, or ≥60%).
The numbers indicate how often a significant p-value was observed in the four data sets. Here only data are shown which were significantly biased with all four tested thresholds. Green and red colors indicate that the base is significantly over- or under-represented, respectively, in the flanks of methylated CpG sites. As an example, the p-values observed for overrepresentation of flanking nucleotides at methylation levels ≥90% are shown in .
Correlation of DNA methylation and gene expression.
(A) Inverse correlation of DNA methylation and gene expression. DNA methylation data obtained in HEK293 and leukocytes were plotted against the normalized SAGE expression data in the respective cell type. (B) Inverse correlation of DNA methylation and PIC binding. The p-value for the enrichment of unmethylated genes in the amplicons with PIC binding was calculated by exact binomial test.
Correlation of DNA methylation and histone modification.
(A) Association of low DNA methylation levels with high levels of histone H3K4me3 and histone H3K9ac/K14ac. The distances between literature-derived H3K4me3 and H3K9ac/K14ac sites in HepG2 cells and amplicons studied in this project were calculated. The fractions of amplicons with different methylation level were plotted for various distances. (B) Enrichment of polycomb binding sites in amplicons with increased methylation in HEK293 or HepG2 cells as compared to fibroblasts or leukocytes. The figure displays the fraction of amplicons with increased methylation (>30%) within the whole data set (light grey bars) and within Suz12 bound amplicons (black bars) (which is indicative of polycomb binding). p-values are given for each comparison.
Gene ontology analysis of genes with different methylation states.
Allele-specific DNA methylation.
(A) Allele-specific methylation of two amplicons (176_1 and 176_2) in the promoter of the CBR1 gene. For 176_1 clones were sorted according to the presence of a deletion (dbsnp rs41563015) in the bisulfite sequencing results. For 176_2, the clones were sorted according to the presence of C/G SNP (dbsnp rs25678). (B) Allele-specific methylation of amplicon 23_2 from gene C21orf81. A/C SNP (dbsnp rs56270809) was used to differentiate alleles. The positions of all SNP sites are indicated by arrows. Each row corresponds to one clone of bisulfite PCR products. Each column corresponds to one CpG site in the studied region. The color codes indicate the different methylation states of each CpG site in each clone. See for details on the methylation patterns of these amplicons in other tissues analyzed.
Alleles*
Base Pairing*
Chromosomes, Human, Pair 21/genetics*
CpG Islands
DNA Methylation*
Epigenesis, Genetic*
Promoter Regions, Genetic/genetics*


Weleda Eucalyptus Plantago Comp is a chest rub for relief of respiratory conditions.
The extracts of Plantain and Hypericum are useful to soothe chest congestion, and the rosemary and camphor relax the constricted chest.
Weleda Eucalyptus Plantago Comp contains:Infusion, % w/w equiv. dry plant: Plantago lanceolata, leaf 0.57%; Hypericum perforatum, flowering herb 0.19%. Oil extract, % w/w equiv. fresh flower: Hypericum perforatum 1%. Oil extract, % w/w equiv. dry leaf: Plantago lanceolata 2%. Camphor 2%; Eucalyptus Oil 1%; Rosemary Oil 1%.
Rub into the chest morning and night as required to relieve chestiness.
Weleda Eucalyptus Plantago Comp. Chest Rub 36ml has not been rated yet.


Is it just me, or does anyone else feel the need to change themselves after seeing an ex? Maybe it's just because on the inside, we figure if we appear the same as when we started dating, we'll get them back.
I don't even have any solid thoughts on this; All I have are moving fingers, emotions, and a keyboard.
I've spent so much time on you, thinking what you had going was a better shape for the world; I've just now realized that you were shading me, you were preventing me from taking what I wanted from all of this. I didn't wear what I wanted, because you claimed the style, I didn't listen to what I wanted, because you liked it under wraps, I listened to you, and I put a damper on myself.
I quit my scene. I quit you. I do it so well.


First decide if the note is a line or space. Then count which line or space it is. Then recall the tools for determining the letter for that line or space.
Spaces-All Cows Eat Grass. Always start from the bottom and count upwards.
Write your answers in order on a separate pieces of paper.


text:
The 5 worst video games of 2016
by Marcos Thadani ● Last updated on Dec 28, 2016
No matter where you look, the truth is that movie licensed games simply have not been very good. From Enter the Matrix to Avatar, games based on popular movies have been mostly an excuse by video game publishers to make some extra cash by taking advantage of the hype surrounding major Hollywood blockbusters.
And this Ghostbusters game is no exception, as it's a run of the mill "twin stick shooter" with an underdeveloped story, characters and poor level design. Actually the levels are quite big but there's a shocking lack of content in them, although hunting ghosts with the movie's iconic proton weapons is still fun in short bursts and the game's licensed soundtrack does add to the atmosphere, but overall players will have a hard time fighting the boredom as this Ghostbusters game is still one of the worst to have hit consoles in 2016.
Next: 2. 7 Days to Die
OR JUMP TO: 1 2 3 4 5
German company Crytek to eliminate five studios in big downsizing move
Guillermo del Toro lashes out at Konami again


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redpajama_set_name: RedPajamaGithub


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If your asphalt driveway is faded and showing its age, you may be wondering what you can do to bring it back to life. As long as the base under the driveway is still in good shape, you probably won't need to tear out the old asphalt and install a new driveway. Depending on the degree of wear and tear, you can have a sealcoat applied or have the asphalt resurfaced.


Research by the Jubilee Centre reveals how the Big Society is ultimately intended to be the solution to the social problems of what Conservatives were describing before the 2010 general election as 'Broken Britain', but this has not been well publicised. In reality it is highly unlikely that any Big Society ambitions can succeed without the help of faith groups. Motivated by a love of neighbour, Christians will want to take any new opportunities that arise to play a greater role in their communities, including starting social enterprises and bringing biblical principles and social transformation agendas to business. The church must also be prepared, however, to defend its own autonomy and help promote religious freedoms.
« Is divorce becoming less socially acceptable?


Well, the important thing is that while this person is donating orgasms or taking d*ck breaks they are also looking out for the safety of those on motorcycles.
It seems like you just started adding random things to that list. Midgets and DSL make you hard? Really?!
Save the money, I highly doubt that its going to help you anyway.


Social media has a problem with piracy. A rudimentary search on Facebook turns up films, TV shows and sports events that should be pay-per-view or subscription based. A reported one billion (yes, you read that right) people have watched Game of Thrones season 7 via illegal downloads or streams (only 31 million watched it legally)….
Next articleWeekly martech review: Sisense raises $80m, Adobe updates video suite, iHeartMedia acquires podcasting business.


text:
Far Future Horizons
The True Story behind the Hunt for Red October
Today on Far Future Horizons we will reveal the true story that inspired Tom Clancy's best selling novel The Hunt for Red October (1984) and the motion picture that was produced in 1990 and starred Sean Connery as Captain Marko Ramius and Alec Baldwin as Jack Ryan.
The film received highly positive reviews from critics and was one of the top grossing films of the year, grossing $122 million in North America and $200 million worldwide. The film also won the Academy Award for Best Sound editing in 1991.
In 1975, The Sentry, a state-of-the-art Russian warship, was taken over by a rogue Soviet officer. This remarkable mutiny not only inspired the best-selling political thriller and the Sean Connery and Alec Baldwin block buster, "The Hunt for Red October," it almost triggered World War III.
For the first time, The True Story takes you deep into the details of the events depicted in the film, revealing firsthand accounts of bravery and tragedy from the men aboard the warship and the officers who ordered its destruction, triggered World War III. For the first time, The Real Story takes you deep into the details of the events depicted in the film, revealing firsthand accounts of bravery and tragedy from the men aboard the warship and the officers who ordered its destruction.
This episode of The Real Story (also known as The True Story) behind The Hunt for Red October is available from Amazon.com.
The True Story: The Hunt for Red October
Copyright Disclaimer Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational or personal use tips the balance in favor of fair use.
Labels: Alex Michael Bonnici, Cold War, Hunt for Red October, Soviet Union, submarine warfare, The Real Story, The True Story, Tom Clancy
The Spaceships of Walt Disney - Man and the Moon
Today on Far Future Horizons we present the second installment of Walt Disney's acclaimed television series Man in Space depicting the...
E = mc2: A Biography of the World's Most Famous Equation
Albert Einstein's name will forever be linked with the famous equation E=mc 2 equating mass with energy. It is perhaps one of...
Stephen Hawking: Into the Universe – The Story of Everything
Today on Far Future Horizons we present the third and final episode of Stephen Hawking's "Into the Universe". In this installment we d...
Carl Sagan - A Cosmic Celebrity
Today on Far Future Horizons we commemorate the eighty-third birthday of Carl Sagan and are proud to present a biographical documenta...
The Three Rocketeers
Today on Far Future Horizons we present the BBC 4 documentary The Three Rocketeers , about the men behind the revolutionary singl...
The Mighty Saturn V Rocket
Today on Far Future Horizons in order to commemorate the forty-fifth anniversary of the greatest scientific and technological achievem...
The Mystery of Planet 9
Planet 9: Have We Discovered A New Planet In The Solar System? Today on Far Future Horizons we present another exciting episode f...
Prophets of Science Fiction - Arthur C. Clarke
Today on Far Future Horizons we commemorate the memory and centennial birthday of Science Fiction writer and visionary Arthur C. Clar...
Space 1999 ~ Breakaway
Today marks the Eighteenth anniversary of a special date in SciFi History. On Monday September 13 th , 1999 in the SciFi Universe o...
L5 First City in Space
Today on Far Future Horizons we would like to present a very hopeful vision of the human future rooted in the work of space visionar...
Man Conquers Space
The Universe - Deadly Comets and Meteors
The Universe: How Big, How Far, How Fast
World War 2 as seen from Space
Man vs. Universe ~ Mars Is Ours
Man vs. The Universe ~ How To Kill An Asteroid
Wonder Women: The Untold Story of American Superhe...
Turn me into a Superhuman
Carl Sagan's Cosmos ~ Blues for a Red Planet
Man vs. The Universe ~ Mining the Moon
The Hunt for the Higgs Boson
The Science of Superheroes
DaVinci ~ The Lost Treasure
Arthur C Clarke's Mysterious World - The Great Sib...
Carl Sagan's Cosmos - "Heaven and Hell"
Carl Sagan's Cosmos – The Harmony of the Worlds
Carl Sagan's Cosmos – One Voice in the Cosmic Fugu...
Origins – Back to the Beginning
Origins – Where Are All the Aliens?
Cosmos - The Shores of the Cosmic Ocean
The Fabric of the Cosmos Episode 4
Jules Verne's Master of the World
An American Adventure - The Rocket Pilots
Origins - How Life Began


text:
Anything relating to technology.
By Ruina and Ritaja
A few months ago the PTO and two Sprague teachers, Mrs. Chiesa and Mrs. Vani, created a Shark Tank program designed for kids. Mrs. Vani already had experience with inventing a product, having sold a workout product called Ab Master a while ago. Mrs. Chiesa and Mrs. Vani also do an event called the invention convention in 2nd grade, which is similar to the Shark Tank we do, so they have some experience off of that too.
After asking people involved in this activity, Shark Tank, some questions, we managed to discover their opinion on Shark Tank, as well as why they joined and what they are inventing. The kids that we interviewed, Saira, Reyna, and Nanoko, all have different reasons on why they started doing Shark Tank, and different ways that their life has been impacted by this event. Saira wants to help people who are struggling with something, while Reyna found it interesting. Nanoko saw it on TV, and when her partner asked her to join, she thought it would be fun to try it out.
It has had an impact on all their lives by seeing what it would be like from the business person/inventors point of view. Reyna and Saira have actually decided to work together with some of their other friends, such as Alexandra and Ritaja. Nanoko and Veda have decided to work on a project together as well. Reyna's group is making "The Cookie Bucket". This invention will cut down the time of making cookies and is easy to wash/clean. It is a bucket with markings to fill up to for some ingredient. There are inserts for whichever cookie you want to make. Nanoko and Veda are making something called the "Get Set Go Clock", quoted by Nanoko, "A Get Set Go Clock is a reminder clock that reminds people what to do at what time so, you won't be late in doing things". These inventions are trying to solve different problems that people, including us, have faced, but there are other ways to figure out what product to make. Everyone had access to the Baxter Lab, to build their prototype. The Baxter Lab is a lab where there are 3D printers, lasers, wood carving machines and many more.
The day of the presentations of the Shark Tank, sharks, that are not known right now and are not Mrs. Chiesa and Mrs. Vani, will go around looking at a presentation about your product and your elevator pitch. An elevator pitch is a 30 second snippet where you tell the Sharks about your product, why they should "invest" in it, and leave a memorable impact on them to keep them thinking. Your presentation can be a slideshow, poster board, keynote, whatever you like. While the Sharks won't actually be purchasing your product, you are still allowed to sell your invention if you figure out how. Currently, the program is not giving out prizes, but if it works out this year, they are planning on adding prizes in the future.
By: Dhruv
The National Science Bowl (NSB) created by the U.S. Department of Energy (DOE) in 1991, is a highly competitive science academic event which students, particularly higher achieving middle schoolers and high schoolers are involved in. Science Bowl consists of many science and mathematical problems which students study often to be prepared and to solve the equations. Schools from all around the world participate in this event, and from each school in tournaments, 5 dedicated students, one dedicated alternate student, and dedicated coach(s) will be participating in the tournament. The group of students do certain math and science activities which they can achieve fame and prizes in, like shown in the picture above. There are 2 different teams, the academic team (a team that solves problems), and the car team (a team that builds cars to compete). 8-10 people are in the academic team, and 4-6 people are in the car team. The scholars also travel to many different places to play in the different tournaments. Aaroh, a student in Science Bowl, says, "To practice for upcoming competitions, we study sets of problems to understand the concept better." Students in Science Bowl practice twice a week for about an hour each practice, which the members are expected to attend to. He also says, "Science Bowl is like science jeopardy, but harder." They have to use buzzers to answer questions instead of having a plain old written test. Science Bowl also designs and builds a model car to race against other schools within our region. Currently, according to research by recent studies, it is proven that by the beginning of 2019 for Science Bowl, there will be 9,000 high school students and 4,500 middle school students, which is a huge amount of people. Daniel Wright's team is amazing, and we should root for them. They are the former regional championship champions. Good luck and GO DW!!
If you want to learn more about this topic (Science Bowl), you can visit the following websites to explore and learn more facts about it:
https://d103.learning.powerschool.com/kperri/extracurricularactivities/cms_page/view/32709896
https://science.energy.gov/wdts/nsb
THE MODERN SPACE RACE
The first space race occurred in the 1960s. It was a heated battle between the United States and the now defunct Soviet Union. Now, in 2019 a new heated battle for privatization of space travel has arisen. There are four main competitors.
SpaceX Virgin Blue Origin ULA
Founded and run by eccentric billionaire owner Elon Musk, SpaceX is best known for its extremely successful Falcon 9 and launching a car into space on the Falcon Heavy, a variant of the Falcon 9. The Falcon 9 is a 23 story tall twin stage rocket that has a reusable first stage. The Falcon 9 has around half the government contracts for national security and the International Space Station, who they supply. The Falcon 9 is also used in the private sector. English conglomerate Virgin has two units that deal with space travel. The first, Virgin Galactic, is known for its quad engine, dual body plane, White KnightTwo, which launches an eight seater reusable spacecraft, SpaceShipTwo, from between its wings. At the end on 2018, Virgin launched SpaceShipTwo into sub-orbit with passengers in it for the first time, starting its era of space tourism (only $250,000 a pop!). Virgin's second branch, Virgin Orbit, plans to launch smaller, lighter cargo rockets from the wing of a 747. Although this is only in prototype stage, it still works and will be somewhat revolutionary, as this is a less expensive way to launch a rocket, by around $70,000,000 Blue Origin, a space flight company run by Jeff Bezos, the founder of Amazon, specializes in suborbital rockets. The first rocket is New Shepard, named after one of the first American astronauts, Alan Shepard. It is nearing the end of its testing stage, and will soon not only carry experiments, but humans. Just like Virgin and SpaceX, the New Shepard is reusable. Blue Origin has a second rocket, although only on paper.They have designed the New Glenn, named after famed astronaut John Glenn. The New Glenn is a is a two stage, 31 story rocket with nine engines. Although it has not yet been built, it has already secured national security contracts and others in the private sector, most likely because it has two times as much storage then any other rocket on the market. ULA is an acronym for United Launch Alliance, a joint venture between national security contractors Boeing and Lockheed Martin space divisions. They hold the other half of the United States space contracts. They are producers of the Atlas family, and the Delta family, both of which are cargo rockets. ULA is also working on the starliner, a replacement for the cargo pod atop the Atlas 5, so the Atlas can launch astronauts, and is expected to start ferrying astronauts to the ISS this year, limiting our dependence on Russia's Soyuz for transportation.
The Falcon 9 illuminated at its Vandenberg, CA launchpad.
An under view of Virgin Galactic's WhiteKnightTwo, with SpaceShipTwo underneath.
Virgin Orbit's 747-400 with the LauncherOne attached.
New Shepard illuminated at night at its west Texas launch site.
Blue Origin's New Shepard flight path. The Karman line is defined as the start of space and you can earn US astronaut wings if you go above it.
Blue Origin's New Glenn Rocket, as compared to a human (Which is the tiny grey spec in the bottom right corner).
A ULA Delta IV heavy taking off in California
A ULA Delta IV on the launch pad
A ULA Atlas 5 approaching the launch pad. This launch is carrying the Mars probe Curiosity.
Black Holes: Yin and Yang
By Smaran
In every end there is a beginning. For every beginning there is an end. When life is take away, life is also given. We all know that the standard black hole devours and destroys and it is the end of all things. We know that once something enters the gravitational field and has passed the point of no return, kaput. But what if i told you that a black hole actually could give life. When you think about it while factoring in the information and evidence, it starts to piece together so just here me out. The incredibly immense gravitational pull of the black hole – what we call its tidal force, the same force that the Moon exerts to cause the ocean tides (only on a much larger scale) – will tear the star apart, and devour, or accrete, the remains. But if the star is a white dwarf, the evolutionary endpoint of low- to middle-mass stars like our Sun, something interesting can happen. In these white dwarves, hydrogen fusion has already come to a halt before they get gobbled up. But as the black hole's tidal forces simultaneously stretches and compresses the star in opposing directions in what is called a tidal disruption event, the compression can actually reignite fusion in the star's core, even if just for a few seconds, according to new simulations. The destroyer of worlds instead feeds the spark of life.
But here's the catch: this can only happen if it's an intermediate mass black hole. For some reason, those seem to be missing from the Universe. There are two categories of black holes in the Universe. There are your regular stellar-mass black holes, typically below around 100 times the mass of the Sun. These are the ones whose collisions are responsible for gravitational wave observations. Then there are the supermassive black holes, ranging from a lower limit of around 100,000 solar masses, but ranging up to millions or billions of solar masses. Sagittarius A*, the supermassive black hole at the centre of the Milky Way, is about 4 million solar masses. But the problem is that neither stellar-mass nor supermassive black holes will produce the white dwarf resurrection effect. It is basically as Goldilocks being the dwarf star and the little bear's stuff being the teenage black holes. A stellar-mass black hole is quite physically small, which means that initially the white dwarf will engulf it; and a supermassive black hole's tidal forces are so strong that the star will fall into it before it can be disrupted. Only the teenage sized black holes provide just enough leeway for the process to happen.
But for the sake of the article, lets just say that it actually happened. If a white dwarf was to be swallowed by an intermediate mass black hole, the reignited nuclear fusion can convert the typical white dwarf composition of helium, carbon, and oxygen into heavier elements such as iron and calcium. Simulations show that, when the white dwarf is a little farther away from the black hole, more calcium is produced; but when it's closer, more iron is produced. Since not all of the star ends up devoured by the black hole, these elements can then be blown out into space, where eventually they'll be incorporated into new stars. So it is basically a win win for both the black hole because it is getting more food and for the universe because it just had a couple of new stars born.
And you can make your own star for the low low price of your soul, Mc. Scrooge's bank account (Duck Tales), and the Eye of Vishnu. If you give me that then with a little compression here, a time machine there, a white dwarf over there, and a whole lot of matter all the way over there (I don't know why we need matter but what's the matter with you), you will make your own little star! Batteries not included.
Like how for every beginning there is an end, this is the end of this article and this series, and thank you for reading the black holes series. If you have any ideas, please ask this email account, smaran.tadepalli@gmail.com and no it is not my real name and my actual account.
Black Holes: Introduction
Black holes, a bundle of information that no one can read. They shatter what was regular physics and create a whole new dimension. What is a black hole? Black holes are naturally formed when the largest stars, those with more than 20 times the mass of the Sun, collapse violently and explode. Here the density of matter is so high, the escape velocity exceeds the speed of light.
Think of it this way, space is a blanket held taut and the objects in space make divots in it depending on the mass of the object. The larger the object's mass, the bigger the divot. A black hole makes a divot so deep that the speed that you need to escape the black holes is faster than the speed of light, which the speed of light itself is impossible (speed of light: 299,792,458 m/s).
Scientists can find black holes by seeing warped light. Around a black hole, light is warped because of the black hole's gravitational pull, which is kind of obvious. Also, when they pass between you and another object you can see the space distortion and a red aura if the black hole is eating something. They even give of the radiation in the ultraviolet spectrum. But the most noticeable act of a black hole is when the overload and spit out lots of energy that can strip planets and maybe even whole solar systems of their life and each of their planet's atmosphere.
If you are scared about black holes and think that no one will ever remember you if you've sucked into one, don't worry because your image will always be on the surface/ event horizon of the black hole and everyone who is unfortunate enough to come that close to a black hole will see it thanks to the magic of time dilation. If you think that your image will fade away then don't because through the magic of time dilation your image will stay there and just redden one tint per eternity for the low low price of you dying to a black hole. The only thing you should fear from a black hole is the agonizing pain of your body stretching as it gets stretched until it is one atom thin, but it all happens in a flash for you but the viewer never sees it happen through the magic of time dilation for the low low price of you dying to a black hole.
Why does Daniel Wright use iPads?
A quick comparison of the American School favorite, the Chromebook, and education's underdog, the iPad
By: Alex and Smaran
In over 50% of schools in the United States, which is equivalent to around 10 million students, Chromebooks are used instead of iPads, so why doesn't D103 use Chromebooks too? To figure out why, we compared the two more work focused iPads with more Chromebooks at different expenses. Based on the evidence below, we found that higher quality Chromebooks are normally more expensive. For example, a 12.3 inch Google Chromebook with 512 gigabytes of storage costs over five hundred dollars more then the equivalent, larger iPad. Although the less expensive Chromebooks may cost a lot less than a baseline iPad, they are bulkier and heavier. And, if you look at the dollar per gigabyte of memory value, the $409 iPad is a better deal then a $259 Samsung Chromebook, at $3.19 per gigabyte to $8.09 per gigabyte.
Also, Google charges a thirty dollar management fee for schools. This fee might seem small for just one Chromebook, but it forces the Chicago public school district to pay 33.5 million dollars on around 134,000 Chromebooks. If D103 had to pay the management fee for a Chromebook per student, they would have to pay around $53,000 for over 1500 Chromebook. If you throw in the cost of 1750 new Chromebooks, it adds on another $453,250. And that doesn't even account for the apps and custom software add-ons.
Basically, although Chromebooks are more popular in America's schools, the iPad is a much better deal for schools. And, if you add in the new gen. six's Apple pen capability, the iPad becomes an even better deal. Those plentiful reasons for buying an iPad instead of a Chromebook is why our school district uses iPads instead of Chromebooks.
Less Expensive Chromebooks
Acer with 16 gigabytes of memory: $109-$299
Dell with 16 gigabytes of memory: $149-$199
Samsung with 32 gigabytes of memory: $259
More expensive Chromebooks
Google with 128 gigabytes of memory: $999
Google with 256 gigabytes of memory: $1199
32 gigabytes of memory: $309
128 gigabytes of memory: $409
10.5 inch display
512 gigabytes of memory: $1129
32 gigabytes of memory: $299*
128 gigabytes of memory: $399*
*discount not included
Bestbuy.com
Technology: The Problem With Beats
By The Audiophile
Beats. Everyone's favorite brand. They cost upwards of $200, but they are made of one of the cheapest materials possible, plastic. The headphones' built-in audio settings pump up the bass so high that they overpower the mids and highs that you can really appreciate with a pair of nice Sennheisers, V-Modas, Bose, or even a pair of Sonys.
Another reason why having the bass cranked up too high is that is can tear the drivers, the bits of metal and magnets that create the sound. The headphones give a sense of quality by adding metal to parts that might as well be plastic. Metal increases a sense of quality because it feels heavier, and it is usually a more expensive material when compared to the plastics that headphones are made of. Another problem with Beats is that they will put pressure on your eardrums from the high bass, which causes the listener great discomfort.
On the other hand, you could spend the money that you were going to spend on beats on a nicer pair of high-quality headphones like Bose or V-Moda. They're usually packed with features like active noise cancellation and/or great sound quality. V-Moda has been dubbed "The Beats Killer". Another great brand that offers high-quality audio products is Bose. Their headphones have a great sound range, and they even make very nice speakers. Finally, a more budget option with very good sound is the pair of headphones that look like they would be from on an airplane. They are called JVC Flats. While they don't look the best, they have very good sound for the $12 that they cost.
If you're looking for a nice pair of earbuds, it would be a good idea to get the Blue Ever Blue 328R in ear headphones. These cost $35 on Amazon.com, and have very good sound quality. The difference between these and a normal pair of earbuds is that these use the HDSS (High Definition Sound Standard), with ETL technology. It prevents pressure buildup in the earbud due to heat, which distorts the sound. This makes the sound crisper and clearer.
Beats might be mainstream but mainstream isn't always the best solution. Picking up a pair of Boses or V-modas will increase quality and give you extra features. Never settle for less, don't get Beats.


BATON ROUGE, LA (WAFB) - The East Baton Rouge Metro Council voted Wednesday night to change an ordinance so that polling places for the upcoming election can by moved.
More than 60 precincts were damaged following historic flooding in August, which affects about 35,000 voters. The election on November 8 will have voters in the parish deciding on a new president, a U.S. Senate seat, six U.S. representatives and several local races.
Councilwoman Chauna Banks-Daniel said it is important that voters not allow the flood to keep them from the polls.
"Of course this is the year where we have an opportunity to vote for a new mayor and several of our council seats, the majority of our council seats are up for election so as local government and all the things that are going on in our city-parish government more than ever we need our residents and our voters to be active in voting," she added.
The change will include polling places in wards one, two and three in the parish. Voters can contact the Registrar's office for more information.


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Blog post June 16th 2022
Laying the foundations for a collective eco-sufficiency policy
From a little-known and poorly understood concept, eco-sufficiency has gained traction in recent months to the point where some now regard it as an "unavoidable debate". While the issue still has the potential to polarize, the fact that it is being cited by an increasing number of actors, including at the highest governmental levels, is opening a new arena of political debate. But what exactly should be debated? And how can we build the political foundations of a collective eco-sufficiency project?
What should be debated?
The concept of eco-sufficiency refers to the idea of reassessing our needs and the ways in which they can be met, that would reduce our (over)consumption of energy and resources, without having a negative impact on our well-being1 . For example, moderating the use of heating in winter and of air conditioning in summer, choosing vegetable protein over meat, and maximizing the lifespan of our clothing. All of these actions, alongside efficiency efforts and technological innovations, would strengthen our ability to stay within planetary boundaries.
So why can't an eco-sufficiency policy focus solely on the call for individual action, and why does it need to be a subject for debate?
i) An eco-sufficient individual in unsustainable infrastructure. It is difficult for an individual to adopt an eco-sufficient lifestyle within a framework of unsustainable technical systems: for example, we depend on many digital services whose practices in terms of storage, design and promotional content are not eco-sufficient; we also depend on a mobility infrastructure and an employment and housing market framework that have implications in terms of car use. It is society as a whole, including its technical systems and diverse actors, and not only individuals, that must move towards eco-sufficiency.
ii) An eco-sufficient individual in a consumerist society. We are social animals: our wishes, needs and representations of what is necessary and desirable are part of the fabric that binds us together. In our modern States, this social cohesion, also shared with economic actors, is the promise of access to material abundance2 . Therefore the rationale of moderation is not self-evident and requires a real debate, even if it has always existed in society, driven by different principles (withdrawal from the consumer society, adoption of so-called alternative lifestyles), different beliefs (religious, spiritual) and different practices (anti-waste, re-use).
iii) Inequality and eco-sufficiency. We are not all equal in relation to the objective of eco-sufficiency. Some people are more limited than others in terms of their material or geographical situation. More affluent households have a larger ecological footprint on average. While for a major proportion of the poorest households, greater consumption means greater access to the consumption trends of the middle class, the standard of success that our society has established. The question of effort sharing and the pace of change, according to the limitations and capacities of each individual, therefore requires organization. Regarding food, for example, should we not exploit the potential desire and economic capacity of more affluent classes to be a driver of the transition?
In this context, the democratic/political debate would have several objectives:
The first objective would be related to the State discourse
Acknowledging the collective responsibility to act and to avoid the over-accountability of individuals, which can discourage, in particular the most financially constrained individuals or those who have built their life on material abundance. The State must explain how it can be exemplary in implementing eco-sufficiency. It is also important to go beyond the preconceptions about what changes are necessary: can the State legitimately interfere with our lifestyles? Would this be a restriction of freedoms? Is it possible to change lifestyles? (See article [in French] published by Mathieu Saujot on bonpote.com on 10 misconceptions on eco-sufficiency).
The second objective is planning the evolution of our technical systems
Technical and production systems must evolve to enable greater eco-sufficiency. The consideration of the joint evolution in terms of supply (e.g. less car mobility and a move towards a fleet of smaller, lighter electric cars that are accessible to all; agricultural production focused on less but better, and agro-ecology for meat) and demand (e.g. increasing valorization of alternative modes of transport; a more sustainable food supply that valorizes less but better) requires unraveling of connections between a diversity of private and public actors as well as consumers and citizens. These connections can be financial (e.g. making electric vehicles accessible to all), related to synchronization (e.g. a decrease in livestock farming and an increase in quality, in parallel with a change in food demand), or related to the invention of new economic models. Planning, as a complement to the market, therefore takes on its full meaning as a tool for the coordination of action to be taken. In addition, it should be made tangible, for example, in the future French Energy-Climate Strategy (SFEC), and in the roadmaps of various ministries.
This work must mobilize government and administrations–in particular the new French General Secretariat for Ecological Planning–but can also be based on citizen participation (for example, through the états généraux sectoriels). The Citizens' Climate Convention (CCC) has clearly shown the usefulness of mobilizing citizens to debate changes in our mobility, agriculture and food systems, to deliberate on what is desirable, the speed of change, the need for support, etc., in a way that complements the work of experts. We are not therefore starting from scratch, as the CCC has initiated the work. It should be noted that the final report mentions the word "sobriété" (eco-sufficiency) 31 times, in the context of the digital world, energy, responsible production and the future of work. The principle is also present in the proposal to reduce the speed limit on French motorways to 110 km/h, the proposal for penalties on heavy vehicles, and proposals for the stronger regulation of advertising.
The third objective is to lay the foundations for a new social contract to achieve this transition
Our lives and our thoughts on progress and achievement are framed by the terms of a type of implicit contract 3 that links access to material abundance, political rights, the sharing of effort and economic and social value, and the ability to emancipate oneself within society. Today, this contract is undergoing a double crisis: firstly through the social dynamics of inequality, distrust and abstention, but also because material abundance is no longer a sustainable source of human progress in developed countries (Jackson, 2017); and secondly because basing (the promise of) social harmony on ever more material abundance is simply no longer possible within planetary boundaries.
There is therefore an urgent need to re-examine this package, which goes well beyond the scope of climate change and requires a broader debate. Indeed, if this was partly initiated by the CCC–the proposal, which was not retained following the final vote, to reduce working hours was presented in a rationale of eco-sufficiency, social justice and citizenship–the work could not be carried out because of its much wider ramifications going beyond the roadmap set out by the Prime Minister. Proposals for social food security or universal income, experiments such as territories with zero long-term unemployment or a reduction in working hours will all be elements in the discussion; as well as the reflections that link trade deficit, eco-sufficiency and relocation. This would also be a form of response to the democratic crisis we are undergoing and to the feeling of division within society, to which ecological issues may constitute a way out (see the recent survey by Destin Commun). Discussing the modalities of sharing efforts towards eco-sufficiency in a logic of equity will be a central dimension (we will revisit this issue soon in a second eco-sufficiency blog post).
1 See the definition in the recent IPCC report, AR6 WG3: "avoid demand for energy, materials, land and water while delivering human wellbeing for all within planetary boundaries".
2 For an in-depth analysis, see: Abondance et liberté, P. Charbonnier, 2020, La Découverte.
3In Abondance et liberté, P. Charbonnier traces the joint construction of our political "software" (freedom, equality, etc.) and our economic system based on the consumption of material resources. If we are to radically change our relationship with these resources to remain within planetary boundaries, then our political software must necessarily evolve: "the transformation of our political ideas must have a magnitude at least equal to that of the geo-ecological transformation".
Mathieu Saujot
Director, Lifestyles in transition
Research Fellow, Lifestyles in Transition
Report December 2022
Successfully implementing low-emission mobility zones, with businesses, for businesses
Marjorie Mascaro
Autre publication November 2022
Ecology and climate: what are the French ready to accept? An insight based on opinion and research into the acceptability of public climate policies
Lucas Francou
Issue Brief October 2022
What social contract for a finite world?
An urgent need to combine sufficiency and solidarity
(article in French)
Other publication September 2022
Sustainable food voucher: analyses and proposals to reinforce the accessibility and sustainability of food
Charlie Brocard,


WASHINGTON — President Donald Trump is urging Americans to get vaccinations to prevent the spread of measles.
CHICAGO — An exhibition that producers are touting as a 360-degree immersive experience to accompany "Hamilton" the musical is set to debut in Chicago.
BRASILIA, Brazil — Thousands of indigenous Brazilians are marching in the country's capital city to protest ministerial changes they say are hurting their people.


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Nubian Museum
The Nubian Museum was inaugurated on November 23, 1997, The building was designed by the late Egyptian architect "Mahmoud Al Hakim" reflecting the traditional character of the Nubian architecture and it won the Agha-Khan Award of Architecture in 2001.
The museum is located 400 meters away from the southern end of the corniche, on the left-hand side of an uphill road, close to the Old Cataract Hotel.
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LITTLEBROOK Courtyard's popular artisan market returns this Saturday, 13th April from 10am to 4pm.
Organisers say, "There will be plenty on offer for visitors to the market. They can look forward to stalls featuring local artists, textiles, ceramics, woodcraft, jewellery and much, much more.
The market will take place monthly, on the second Saturday of every month.


Cosmopolitanism: What Does It Mean to be a Citizen of the World? – Nov 11 | "Let's Talk, New York!"
RSVP to reserve a place.
In recent years, the ancient and perennial idea of Cosmopolitanism has been reanimated by scholars in both the social sciences and humanities – including one of our former guest speakers, Kwame Appiah. They discern in the idea, ways in which people today can respond creatively to rapid social, political, cultural, and economic transformations.
This outlook has deep philosophical roots — from Socrates and the 5th century Greek Stoics who coined the term to declare that they were "citizens of the world," through the universalist ambitions of the great monotheistic religions, to philosophers like Immanuel Kant, and in our day Levinas, Derrida, Appiah, Nussbaum, Barber, Bok, Sen, and Walzer.
In his book The Teacher and the World: A Study of Cosmopolitanism as Education, David T. Hansen, the John L. & Sue Ann Weinberg Professor in the Historical & Philosophical Foundations of Education, proposes that a Cosmopolitan-minded orientation can empower us to address both the challenges and opportunities of our era.
Prof. Hansen provides us with "ideas that can help us do our work and hold true to our values in the face of all the pressures of globalization which bear down hard on teachers everywhere." He observes critically that "globalization" reduces humankind to "human capital" and "emphasizes economic life over the rest of human life" with a premium on production.
Dinner: To augment the fellowship among members this year, you are warmly invited to join other members for dinner at Faculty House at 5:30 PM, after which we will walk to Teachers College for the Seminar, as indicated above. Dinner at Faculty House, a varied and ample buffet (including wine), is $25, which must be paid for by check made out to Columbia University with "dinner" and Seminar 511 noted in the memo line. We will collect checks at the beginning of the meal. If you intend to join us for dinner you must let us know via email a week in advance.
Faculty House is located on Columbia University's East Campus on Morningside Drive, north of 116th Street. Enter Wien Courtyard through the gates on 116 Street between Amsterdam Avenue and Morningside Drive. Walk toward the north end of the courtyard, then turn right toward Morningside Drive. Faculty House will be the last building on the right. PLEASE BRING A PHOTO ID FOR ADMITTANCE TO THE BUILDING.
,The Seminar on Ethics, Moral Educationand Society, chaired by Michael Schulman, brings together scholars from psychology, philosophy, sociology, political theory, education, religion and other disciplines to explore issues in ethics, moral education, moral development, moral motivation, moral decision making and related topics.
Upcoming 2013-14 seminar dates: Dec 9 on Global Obama, Jan 27 on The Power of Conversation, no Feb, Mar 3, Apr 7, May 5.