In September, after taking the TVG high-speed train from Paris to Reims, I toured the city's exquisitely restored cathedral, painstakingly put back together after the devastation and wanton destruction of the First World War. I walked all around town looking at the grand Art Nouveau and Art Deco architecture of the rebuilt city. I sat at a table at a small cafe and watched the people stroll by.
I'd come to the city to see the landmarks and tour WWI battlefields and cemeteries, doing research for the 2017 Centennial of the entry of the Untied States to the war that had already cost Europe the best of a generation. But Reims sits in the heart of France's Champagne region—the thing that draws most tourists—and is home to some of the finest champagne houses. I may have been there to study history but I wasn't going to miss a chance to sip a little bubbly.
Taittinger, founded in 1932, is actually one of the newer champagne houses but its cellars are in some of the oldest of the region's deep chalk caves. During the worst of the First World War the caverns were a place of refuge. They were put into use as a school and hospital, as a shelter during the relentless bombardments. But their history is much older than that. The caves were dug by Romans who quarried the bountiful chalk. In the 13th Century the caves housed the Saint Nicaise Abbey. You can still see the high arches supporting the caverns and the narrow stone leading up out of the caves.
Our guide led us through the long subterranean corridors, past rows and rows of champagne bottles aging in wood racks or stacked into deep alcoves and he pointed out graffiti scratched into the soft walls. Once you become aware of it, the names, dates and rough sketches are everywhere. They are permanent reminders of the fear, fatigue, anger, love and longing that were carved into the man-made rooms that had sheltered men, women and children during the war.
The year 1918—the year the war ended—was scratched in one place, a woman's profile in another. Around one corner I could see a "pickelhaub" the derogatory name for a German soldier's dress helmet during WWI, the one ornamented with a spike at the top.
I tried to imagine what it must have been like to be sheltered there: the ordinary sound of people, of children's voices; the whispers, coughs, and cries of the wounded. Moving from one small pool of light to another, in such long ribbons of darkness, would have frightened me.
The Taittinger cave tour gave me a new appreciation of the ancient history of the land and the strength of the French during the long hard years of war and reconstruction. The Taittinger champagne tasting after the tour only renewed my appreciation for the way the French make wine, especially Champagne.
Posted Jan. 15, 2015, 2:49 p.m.


First Day of My Life: Fall Favorites Swap Reveal!
Ready to link up your awesome Fall Favorites packages?
We hope so! Anna & I hope you had as much fun as we had with the swap!
I was linked up with the beautiful Anna! I'm so thankful for the friendship we share! She is one of those gals that I wish lived closer - I knew we would hang out all of the time!
Looks like fun. Love what you got!
Those candy corn pot holders and towel are adorable!
You got some great stuff - I can't wait to share all my goodies! Thanks for co-hosting, it was a blast!
This is better than other sites.Always so interesting to visit your site.What a great info, thank you for sharing. this will help me so much in my learning..
Yay! I'm glad you liked everything! We make good hosts for these things! ;) You are so sweet and I feel the same way! So thankful for our friendship!
The candy corn themed pot holders are adorable!
how fun! will yall do a winter one?!? new follower!!!


Lady Salisbury and her sons Lord Montague, Arthur, Geoffrey and Reginald Pole, had received much generosity and favour from the King. Arthur was dead by 1536, and Geoffrey was in repeated trouble for debt, but Reginald had been handsomely supported by Henry at Oxford and then at Padua University.
In 1532, Reginald had been sent to the University of Paris to persuade it to rule in Henry's favour in the matter of annulment of his marriage to Katharine of Aragon. Reginald however, from a position where he appeared to be supportive of the annulment, changed his mind. He did not return to England, but remained in Europe, still receiving a pension from Henry, despite his opposition to the King's will.
In June 1536, Reginald sent a letter to Henry VIII. Known as De Unitate it was a coruscating attack on the King, delivered in highly insulting terms. Leaving aside, for a moment, the meat of the letter, its mere existence was an insult and a monstrous example of ingratitude. But the content was even more outrageous. It openly incited rebellion and called upon France and the Empire to invade England, and depose the King. Outraged, the English Government sent assassins to try to murder Pole (although Henry was somewhat equivocal about that type of activity) but he remained safe in Rome.
Confronted by his brother's letter, Montague was shocked, and afraid. He wrote in strong terms to his brother, telling him to desist from such attacks, or he would cast him off as his brother. He persuaded his mother to do the same, which Lady Salisbury did, but in rather less severe tones.


Mobile network EE is to open 50 new stores in 2014 as part of the next phase of its wider retail improvement programme. The new shops are expected to create around 350 jobs.
Deirdre Burns, retail director at EE, said: "This is a truly exciting time for our business. We have just announced that over two million customers enjoy superfast 4G – twice our target for 2013. Our retail team has played a key role in this success and we have no intention of standing still. The High Street is working for us, and we are committed to operating the best shops, in the right locations.
EE's retail strategy also includes a multi-million pound investment programme to modernise its stores, expand its franchise programme, and improve its digital channels.
The company has also announced plans to close a number of stores in selected areas where there are multiple EE shops in close proximity to one another. EE said customer advisors from the affected stores would be moved to an adjacent shop while store managers would be re-deployed where possible.


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LuggageHero buys bag-storage competitor Knock Knock City
By Jill Menze | August 26, 2019
The short-term luggage storage market is consolidating, with LuggageHero - one of PhocusWire's Hot 25 Startups for 2019 - acquiring one of its competitors, Knock Knock City.
Terms of the deal have not been disclosed, but the acquisition was first tipped at Phocuswright's Battleground competition in July, where Knock Knock City pitched.
Copenhagen-based LuggageHero will acquire all of Knock Knock City's assets, people and storage locations, LuggageHero founder and CEO Jannik Lawaetz says, and former Knock Knock City locations, all based in the United States, will take the LuggageHero name.
With Knock Knock City, LuggageHero will expand its reach in the U.S. and plans to leverage existing partnerships Knock Knock City has with property management-type companies, including Guesty, Makomi, STRB and Victoria Prime; Knock Knock City also has a to-be activated agreement with apart-hotel brand Domio.
Launched in 2016, LuggageHero currently operates in 26 cities across Europe and North America and has plans to add 15 locations by early 2020. At each of its storage locations, which include retail outlets, cafes and hotels, travelers can book storage space by the hour.
The company says its customers have logged more than one million hours of bag storage at more than 1,000 drop-off points. In February, it raised $1.45 million in funding, putting its total funding to date at more than $2.25 million.
"Knock Knock City offers an exciting opportunity for LuggageHero to expand and strengthen its network of on-demand luggage storage locations in as many cities as possible," Lawaetz says. "As we grow, we will want to build more third-party relationships, an area Knock Knock City has excelled in."
Knock Knock City co-founder and CEO Selin Sonmez will join LuggageHero as country manager for the U.S. and Canada, and co-founder Nikolaos Georgantas will become partner manager for LuggageHero shops and partnerships in North America.
"LuggageHero's acquisition gives our consolidated business a major growth opportunity and extends our services wider and deeper. As the on-demand short-term luggage storage business matures, we will be well-positioned to give our customers the best service available," Sonmez says.

redpajama_set_name: RedPajamaCommonCrawl


Starnet Preferred Vendors: ARDEX Americas, Daltile, Ecore Commercial, J+J Flooring Group, Mannington Commercial Carpet, Mannington Resilient Floors, MAPEI - APAC, Milliken Commercial, Tarkett | Johnsonite, Uzin Utz North America, Inc.
This past year Great Floors had the opportunity to purchase the Coeur Building. An iconic structure located in the heart of downtown Coeur d'Alene. This unique property was built as the Corporate Headquarters of the Coeur d'Alene Mining Company in 1985 and housed their corporate staff until 2011 when the company relocated to Chicago to be closer to the NASDAQ exchange and the commodities market. As one of the most lucrative mining operations in all of North America the CDA Mining Company set out to build not only a one of a kind building but a building that recognizes and emphasizes the beautiful region we call home. The building is located adjacent to the Tubbs Hill Arboritum, McEuen Park and one block from the world class Coeur d'Alene Resort. With breathtaking views of Coeur d'Alene lake and the surrounding area it really is a one of a kind property that could never be duplicated. The property sat mostly vacant for five years until Great Floors purchased the property in October of 2018. Although the building was stunning, it was in great need of maintenance and updating. Our challenge was to feature functional and stylish products from our vendor partners that adhere to the initial vision of the building and surrounding area. We spent countless hours sourcing and selecting products that not only fit our needs but are a reflection of who we are as a company and a region. The end result was a functional workspace that is nearly as beautiful as the view.


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A:Yes. Contact the store as soon as possible after placing the order if there arises any chance of making change to the order .If the order has already been shipped The patron shall return the goods as well.
When something goes wrong in your home, you have a couple of choices. You can opt to fix it yourself and save a lot of money, or you can pay out tons of money to professionals who might not really do a very good job. It makes a lot more sense to take care of certain things yourself, which is why you took the time to learn how to do jobs right. Still, you need supplies and equipment, and what better place to find what you're looking for than SupplyHouse.com. When you shop at SupplyHouse.com, you'll see that they carry everything you need on their website. With such great prices and selection, there's no need to go anywhere else. Do you need to install a new thermostat in your home? Maybe your water heater is on its last legs. Choose SupplyHouse.com to help you find everything you're looking for, and more!
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Cadets clip Hornets in women's soccer season finale
Norwich (3-11-2, 1-9-1) 3 1 4
Lyndon St. (2-12-1, 0-8-1) 0 1 1
1st - 22:10 - Jordan Kacur (Norwich)
1st - 34:49 - Kate Albretsen (Norwich)
1st - 39:58 - Mehgan McMullen (Norwich)
2nd - 71:57 - Kate Albretsen (Norwich)
2nd - 87:36 - Chloe McFarlane (Lyndon St.)
G: Kate Albretsen - 2
A: Ashley Carvalho - 2
Sh: Mehgan McMullen - 14
Sv: Holly Lutz - 1
G: Chloe McFarlane - 1
Sh: Chloe McFarlane - 2
Sv: Johanna Sargent - 15
LYNDON CENTER, Vt. – The Lyndon State College women's soccer squad finished up their 2016-2017 season with a 4-1 loss against Norwich University at the Varsity Athletic Field.
The Hornets' Johanna Sargent (West Brookfield, Vt.) finished the match with 15 saves, while Holly Lutz (Hamburg, N.J.) had one save for the Cadets.
It wasn't until the 22:10 mark that the Cadets were able to get on the board. Jordan Kacur (Red Creek, N.Y.) tipped the ball away from a defender, then ripped a shot that hit off the gloves of Sargent and up into the top of the net.
The Cadets' second goal came off of a corner kick play. Madison Oelker (West Liberty, Ohio) tapped the ball to Ashley Carvalho (Pinellass Park, Fla.) who passed it into the keeper's box. The ball bounced along the ground to Kate Albretsen (Cotuit, Mass.) who knocked it up into the left corner.
In the 40th minute, Mehgan McMullen (Northfield, Vt.) lobbed a shot that made its way between Sargent's fingers and the crossbar, giving the Cadets the 3-0 lead at the end of the first half.
In the 72nd minute, Carvalho gave Albretsen a lead pass through the defense, setting her up with a one-on-one with Sargent. Albretsen placed a shot past Sargent into the right side of the net.
The Hornets' finished off the scoring, after a corner kick from Shelby Sheridan (Enosburg Falls, Vt.). The Cadets were unable to clear the ball as it bobbled around within the keeper's box before Chloe McFarlane (Newport, Vt.) got the final touch, sending a shot past Lutz.
Lyndon went 2-12-1 overall, and 0-8-1 in North Atlantic Conference play this season.
Norwich finished their season 3-11-2 overall, and 1-9-1 in the Great Northeast Athletic Conference.


Experience I have worked as a freelance artist since the beginning of my career back in 2002, after 2005 I joined up with Kinetic House who has been my main employer within this field ever since. Here I handle things ranging from setting the camera equipment, maintenance of equipment, light setup, camera operator, SFX editor, animator, and video editor. As of Feb. 2014, I have been in Chihuahua, Mexico, where I am establishing/setting up our 2nd office location and supervising that the facility gets set-up according to our productions needs and expansion efforts. I also work under my own business/portfolio as HB Productions and my freelance contracts. From February to June of 2014, I worked at a Telecommunications company called Teleperformance, where I handled calls for Fedex and all that it entails. From August 2013 to October 2013 I worked as the Night Auditor at the Crowne Plaza Hotel, where I handled numerous issues ranging from cust complaints to totalling up the revenue that came in over night at the hotel and making the reports for the accounting dept. Before this, I worked at a company by the name of VOLT from September 2010 to June 2013 , here I handled Tier 1 Tech. Support calls for AT&T U-Verse services. Prior to them, I worked at Nucomm International, where I held the same position as in VOLT and handled the same type of customer issues/balances/sched. visits. From August 2008 to October 2008 I worked as a Digital Gaming Instructor at Northwest Vista College; here I briefly taught particle systems and dynamics within the Autodesk 3DS MAX and Maya software environments and helped students prepare their demo reels for graduation requirements in order to receive their BA. Between May 2007 to June 2007 I worked at Etched In Time, here I made 3D models of customer's head in order to make a head bust or a pendant that had someones face engraved into it.
Education I attended Collins College, From june 2002 to May 2005 for my Associates Degree, then I continued with my Bachelors Degree from june 2005 to may 2007. I am also planning on obtaining my Masters Degree in this field.
Speciality I specialize in character modeling, character rigging, and animation. I also handle photoshop for texture creation and asset design for props.
Hardware Proficiency I am a hobbyist when it comes to computers. I enjoy using, playing with, building, repairing, and troubleshooting hardware/software issues on a computer.
Software Proficiency I am very proficient in Autodesk Maya and ZBrush, I have general experience and knowledge of 3DS MAX and MUDBOX.


Success in the music industry is hard to come by, as many have attempted to hit the jackpot and fallen short. Others disappear into oblivion after releasing a hit single or reached the top and fallen from grace.While we acknowledge that succeeding in the music business isn't a walk in the park, both aspiring and established singers can learn one or two things from this article on how to succeed and remain at the top of your music career for years.
Listening to people with only negative opinions on the music industry may impact negatively on your ambitions in music. Your thoughts, beliefs, thinking, and behavior ultimately affects your output. Thus, having the positive-minded people around you remains key to success.
Fans are crucial to the success of any musician since they determine an artist's bottom line. Giving exhilarating performances on your shows is one way to form a connection with your fans – it may even increase your audience. Furthermore, an artist's online presence on platforms such as Facebook, Instagram, and Twitter is essential in creating and retaining a connection between fans and celebrities.
Giving maximum effort and staying focused on your goals are perhaps the two most essential ingredients to having a successful music career.
Not everyone you consider an associate has your best interests at heart. That's not to say that you disregard advice simply from doubt or suspicion. We recommend that you heed constructive criticism, unlike biased opinions.
Being money conscious is good, but not all the time. In some instances, attend events and treat your fans to a free concert, to show that you value them.
You can learn a little bit from other music genres. Don't restrict yourself to listening to only one type of music. Different music genres come with unique beats and melodies which you can incorporate into your work.
A mentor who doesn't necessarily have to be an artist is of great value. A mentor gives free advice, helps in business planning and supports you in trying times. Additionally, you should join a professional peer group where you advise each and help to set realistic goals and ambitions.
Many artists make the mistake of invariably burning bridges and forgetting the ones who helped them on their way up. Being appreciative of other peoples assistances goes a long way in opening doors for you.
Nobody is an island of knowledge. Thus, read and research on pertinent issues affecting the music industry to stay on top of everything. Be in the know of moves made by the leading musicians to get an insight on what it takes to succeed.
As alluring as it is, fame is highly intoxicating. Keep your feet on the ground to retain your focus on churning out great hits.


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Blending nature, the city life of New York City, and the European styles of her childhood, Meira Tugendhaft of Meira T presents fashion jewelry pieces that effortlessly depict the beauty of the world around her. She lives to bring extravagant and striking pieces to life as her love for fashion and travel brings unique and inspiring pieces to the fine jewelry industry. The brand utilizes some of the top trending metals like 14 and 18 karat gold, as well as precious gemstones ranging from diamonds to pearls. With their trademarked off-centered charms, these feminine and wearable modern jewels have cultivated a cult-like following.
Meira T collections are available in varying bracelet types from brilliant beads in white gold and yellow gold to delicate chain bracelets that present intense colorful gemstones and diamonds. Let the fashionista in you really stand out with some of their diamond adorned cuffs in chic and highly in-demand designs made of rose gold and timeless yellow gold. One can also shop Meira T earrings in dramatic drop, outspoken hoop designs, and attention-seeking and diamond adorned stud earrings. The collection of Meira T earrings brings bold and lively design elements in every piece.
Elevate your wardrobe with Meira T necklaces and pendants. Their off-centered charms bring a unique aesthetic that bring art to an-otherwise ordinary fashion statement. From diamond studded pieces that feature highly coveted gemstones to pearl necklaces that seem to glow from within, these pieces inspire high fashion with their exotic and intricate designs. Also available are Meira T fashion rings. These right-hand rings boast uniquely stand-out designs, cuts, and shapes. These pieces speak for themselves with a varying range of colors and hues in their stellar center stones.
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Top 100 Bars 2021
Concert News & Reviews
Local Wire
Phoenix Bars & Lounges
Best of Phoenix
Phoenix's independent source of
Five Years Later: A Look Back at the Investigative Photos of the Yarnell Hill Fire
New Times Staff June 29, 2018 6:00AM
DraftKings Breaks Ground on Sportsbook in Scottsdale
Elias Weiss
Phoenix Airport Workers Rally for Living Wage
Katya Schwenk
Arizona Rattlers Tryout Draws Record Numbers
Fiesta Bowl Makes History in Glendale
New Times Staff
Nineteen of the 20 members of the Granite Mountain Hotshots were killed during the Yarnell Hill Fire on June 30, 2013. More than a half-million dollars in fines were levied against the Arizona State Forestry Division for safety violations after an investigation by the Arizona Division of Occupational Safety and Health. The report included dozens of photos of the fire, taken before and after the deaths of the hotshots. Some of the photos were taken by the fallen hotshots themselves.
Yarnell Hill Fire, Five Years Later: Lessons Not Learned and Five Potential Hot Spots
By Sean Holstege
Weather and fuel conditions are so helpful in predicting fire behavior that state officials now rank the dangers of Arizona communities online.
The noise was deafening at State Farm Stadium on December 31. It was a blend of ecstasy and incredulity, with hands lifted…
By Elias Weiss
The Arizona Rattlers are the winningest arena football team ever. Maybe that's why their open tryout drew record numbers of pro football…
On December 8, the sound of bullhorns cut through the holiday travel buzz at Phoenix Sky Harbor International Airport. "Whose airport?" "Our…
By Katya Schwenk
At TPC Scottsdale, swaths of lush green bermudagrass are dotted by shimmering turquoise water features and blue palo verde trees — all…
Arizona High School Students Stage Walkout Over Anti-LGBTQ Laws
Students at six schools around Arizona, including Hamilton High School in Chandler, walked out of class on September 29 to protest anti-LGBTQ…
Arizona Capitol
Pro-Choice Demonstrations in Phoenix After the Supreme Court Overturned Roe v. Wade
On Friday, June 24, 2022, the U.S. Supreme Court issued a ruling in Dobbs v. Jackson Women's Health Organization overturning the 1973…
By James Deak
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Oyinkan Braithwaite stretches the idea of unconditional love to its extreme in My Sister, The Serial Killer | CBC Radio Loaded
Oyinkan Braithwaite stretches the idea of unconditional love to its extreme in My Sister, The Serial Killer
Braithwaite's debut novel is about a woman named Korede and her younger sister Ayoola, who has an unfortunate habit of murdering her boyfriends. The author joins Tom Power to tell us more about her very dark, but funny new book.
CBC Radio · Posted: Dec 11, 2018 9:21 AM ET | Last Updated: July 25, 2019
Oyinkan Braithwaite's critically-acclaimed debut novel My Sister, The Serial Killer is out now. (Studio 24, Penguin Random House )
Originally published on December 11, 2018
Oyinkan Braithwaite is a writer who's fascinated with the idea of unconditional love. Her debut novel My Sister, The Serial Killer is about a woman named Korede and her younger sister Ayoola, who has an unfortunate habit of murdering her boyfriends. Every time Ayoola takes another life, Korede is there to clean things up. It's a very dark, but funny story that's already been optioned for a film by the producers of Baby Driver. Braithwaite joins Tom Power from Lagos, Nigeria to talk about her new book.
— Produced by Vanessa Greco
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'I have two time-travel shows': Eric McCormack on juggling sci-fi series Travelers and the Will & Grace reboot
Bob Martin on The Prom and how musical theatre can act as an escape from the harshness of life
A gateway to figure skating in film
FULL EPISODE: Tuesday, December 11, 2018: Eric McCormack, Oyinkan Braithwaite and more


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Developing national career development support systems
Pathways to enhance lifelong career guidance, career education and career development support for workers
ILO and ETF
pdfen
pdffr
pdfru
Skills matching
This ILO-ETF joint report discusses how career development support systems can be developed. Departing from previous research and policy work, this publication synthesises lessons learnt and proposes a methodology to perform national system reviews encompassing career guidance, career education and career development support to workers. The approach relies on assessment of key reference points, with strong contextual analysis, avoiding universal solutions for existing challenges. National stakeholder engagement is recommended to develop effective reviews and work towards a shared vision, priorities and planning for system development.
Career development support has become more important than ever. As digital transformation, greening of the economies, demographic shifts accelerate and surprising disruptions take place, individuals navigate an increasingly more complex labour market. At the same time, challenging realities remain in many countries that have high youth unemployment and large informal sectors. Activities such as career guidance, career education and outreach are key to help individuals upskill, retrain, move jobs and manage their livelihoods. Career development support is also key in achieving strategic objectives in educational, training and employment policies as well as to support sectoral skills development.
Did you like this publication? If you would like to be notified when new content like this is published, subscribe to receive our email alerts.


Irish Life, which is owned by Great-West Lifeco, generated strong results, contributing Euro €57 million (CAD$80 million) to Lifeco's profits in the first quarter. This represented a 54% increase, up from Euro €34 million (CAD$52 million) in the same quarter in 2014.
Bill Kyle, Chief Executive Officer, Irish Life Group said that results at Irish Life Investment Managers ("ILIM") continue to support the growth trend at Irish Life Group..


The company recommends appropriate duration is 1 year to maintain the best efficiency. Life span of the filter depends on many factors such as room size, amount of dust or dirt in the area where air purifier is used, environment, and air purifier usage duration. Therefore, customer should check the filter of air purifier regularly.


We are excited to have Dr. Mary Ellen Wiltrout speak on a panel addressing "Perspectives in Competency-Based Education" during the Saylor Higher Education Summit taking place this June 21/22 in Washington, D.C.
Mary Ellen completed her Ph.D.in biology studying translesion synthesis at MIT. From 2009 to 2013, she co-taught the molecular biology course at Harvard University as a preceptor. She also developed several of her own courses at Harvard Extension School. In 2013, Mary Ellen moved to the Broad Institute to be part of the core group to create Eric Lander's MITx course, 7.00x Introduction to Biology – The Secret of Life.
Mary Ellen now oversees the execution and evolution of MIT Department of Biology's digital learning strategy with her group of two postdoctoral scholars along with several graduate and undergraduate contributors. The group develops digital learning content for MIT students and advises evidence-based teaching practices. They also implement these practices in the creation of world-wide bound MITx on edX MOOCs. Mary Ellen's group completes research on the design of digital learning content as well.


It has been well documented that exposure to IPV is a potent traumatic stressor for children, often adversely affecting their physical and emotional health. However, caring adults can help children heal and thrive. The recommendations that follow were created to help guide IPV advocates in their daily work with mothers and families. The recommendations are drawn from a review of core components of evidence-based therapeutic intervention models for children exposed to IPV including Child Parent Psychotherapy, Trauma- Focused Cognitive Behavioral Therapy, and the Kid's Club. Information about these evidence based models and other research on services for children and youth can be found on the Promising Futures: Best Practices for Serving Children, Youth, and Parents Experiencing Domestic Violence website.


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The Treatment Centers, Inc.
Admission / Program Info
Myths About Methadone
Gadsden Treatment Center
Shoals Treatment Center
Myths & Misconceptions About Methadone
Myth #1: Methadone is Addicting
Physical dependence is associated with Methadone.
Methadone is not considered a primary drug of choice for "getting high."
Methadone is administered orally, and compared to most opiates, is slow to take effect.
Methadone does not produce a "rush" like other narcotics.
Myth #2: People Get High On Methadone
Methadone is an opiate blocker, which means that it blocks the craving for opiates once the methadone is ingested.
The "blocking" effect of methadone helps the individual "normalize" their life again.
The "blocking" effect lasts for 24 hours, so the individual will have an opportunity to "unravel" the addict way of thinking.
Once an individual is taking the appropriate dosage, there is no impairment of motor skills or thinking ability (as long as no other psychoactive drugs are taken with it).
Myth #3: Once on Methadone, You Cannot Stop Using It
The first goal of Medically Assisted Treatment is to eliminate the use of opiates.
Methadone is a "tool" used to eliminate the cravings and withdrawal symptoms associated with opiates.
Full participation of individual and group counseling is necessary to change the addictive behaviors of one suffering with addiction. This allows the individual the best opportunity for a successful detox from Methadone.
Myth #4: Methadone Does No Good
Methadone decreases the exposure of diseases as HIV and Hepatitis.
Methadone decreases the possibility of overdoses.
Methadone decreases the amount of drug related crime.
Myth #5: Methadone Hurts Your Health
The health status of methadone patients has been studied more frequently than other medications.
There is no scientific evidence that methadone rots teeth, gets into bones, or causes any other health issues. Extensive drug abuse can lead to neglect of personal hygiene, which can cause health issues.
Taking methadone is safe for expectant mothers.
The above information was summarized from "Myths About Methadone", by Emmett Velten, National Alliance of Methadone Advocates, Education Series Number Three, March, 1992.


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March 13, 2018 / Shelby Bunker
Ever Davies is fat. At just fifteen, she weighs over 300 pounds. And a voice in her head, named Skinny, never lets her forget it. Skinny is always there telling her the awful things other people think of her. But when Ever decides to have surgery and the pounds start dropping, she learns more about herself...
March 13, 2018 / Shelby Bunker/ Comment
Outstanding, Young Adult, Donna Cooner, Body Image, Self-confidence, High School, Weight, Lifestyle, Self-Acceptance
Minnie McClary Speaks Her Mind
March 01, 2018 / Emilee Bell
Minnie, a quiet middle school girl, and her family settle into a new home, school, and employment situation. At his last job, Minnie's father stood up to his unethical boss and was fired. As Minnie's mother begins to work and Minnie's veteran uncle who suffers from PTSD moves into their basement, their family dynamic becomes fairly tense...
March 01, 2018 / Emilee Bell/ Comment
Excellent, Intermediate, Valerie Hobbs, Teachers, Prejudice, Middle School, Self-confidence, Religion, Politics, Bullying, War, Homosexuality


Transfer Your Domain Name Now!
When you Transfer your domain name to We'reDigital, your keep any time that's left on your existing registration and extend it by one year. It matters not which term you choose with We'reDigital, it will be added on top of your existing domain registration.
The expiry date is simple pushed one year further for each year added this is included in all transfers .


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Four things to watch out for in the Middle East in 2023
Abu Dhabi, UAE CNN — The event that dominated the world's news agenda in 2022 was the Ukraine war and…
Why this has been a culturally unique World Cup
CNN — This was never going to be a traditional World Cup. Breaking ground in the Middle East and played for the…
Yasmine Abdelaziz is new brand ambassador of L'azurde in Middle East
The L'azurde Group for Jewelry announced it has picked Egyptian actress Yasmine Abdelaziz as the ambassador of the brand in…
Largest water park in Middle East inaugurated in Red Sea
The Minister of Tourism and Antiquities Ahmed Issa, Governor of the Red Sea Omar Hanafy and President of the Tourism…
Egyptian Defense Ministry to move to new headquarters in administrative capital
Egypt has set towards establishing a new headquarters for the Egyptian Ministry of Defense, the largest in the Middle East,…
bp has been awarded new exploration blocks in Egypt's Offshore Nile Delta
British Petroleum (bp) announced on Monday that it has been awarded two exploration blocks in the Mediterranean Sea, offshore Egypt…
beIN Sports open channel for World Cup matches
Football fans around the world are continuously looking for match dates and times for this early stage of the World…
Climate change could displace millions from Middle East region: report
Several officials have warned that climate change may lead to the displacement of millions of people in the Middle East,…
Cholera rages through Middle East and Africa amid vaccine shortage
Abu Dhabi CNN — Cholera is making a comeback in the Middle East and Africa, and its rapid rise has…
Tara Emad becomes first face of Chanel in the Middle East
Tara Emad, the young Egyptian actress, was chosen by the owner of the famous brand Chanel Beauty to be a…


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Mac Miller Cancels PromoWest Fest Performance Due to 'Personal Health Issues'
Mac Miller has canceled his performance date at Ohio's PromoWest Fest this weekend (the three-day festival will run through Friday, July 15 to Sunday, July 17) due to "personal health issues."
By Adelle Platon
Adelle Platon
Kehlani's Homecoming: Inside Her Touring Wins, and Why Live R&B is 'Obviously Thriving'
TDE's Punch Introduces New Collective A Room Full of Mirrors, Announces Visual EP Release Date
To Celebrate April Fools' Day, Revisit the Time Adele Fooled Adele Impersonators in the Best Prank Ever
Mac Miller Brick Stowell
Mac Miller has canceled his performance date at Ohio's PromoWest Fest this weekend (the three-day festival runs July 15-17) due to "personal health issues."
"Malcolm has decided to take some time off in July to deal with personal health issues," the festival's Twitter account shared on Thursday (July 14), referencing the Pittsburgh rapper's real name Malcolm McCormick. "He apologizes to his fans who were expecting to see him and promises to be back soon." Last month, Mac Miller also axed his set at the sold-out Woo Hah! Festival in the Netherlands.
Maná Cancels Viña del Mar Performance Due to Lead Singer's Knee Injury
Malcolm has decided to take some time off in July to deal with personal health issues.
— PromoWest Fest (@PWFestOfficial) July 14, 2016
He apologizes to his fans who were expecting to see him and promises to be back soon.
Mac Miller on Sobering Up, His Nemesis Donald Trump and the Drake-Meek Mill Beef
Mac Miller retweeted a flier for Fool's Gold Records Day Off show in Los Angeles on Sept. 25, where he is expected to perform alongside Pusha T, MadeinTYO and A-Trak and friends. According to Ticketmaster, his July 28 stint for the Stir Cove concert series at the Harrah's Council Bluffs Casino & Hotel in Iowa has also been canceled.
A rep for Mac Miller did not immediately respond to Billboard's request for comment.
Earlier this year, Walk the Moon canceled their summer tour dates, including their PromoWest stint, so frontman Nicholas Petricca could spend time with his family while his father suffers from Alzheimer's.


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501 foreign workers leave Sverdlovsk Region this year
20 December 2010 (09:17)
'Operations Taxi Van and Illegal Migrant that Sverdlovsk Region's law enforcement officers carry out on a regular basis have led to about 40,000 people facing administrative liability this year; these people were both foreign workers and their employers, who had to pay a total of 72 million RUR. 501 foreign workers had to leave Sverdlovsk Region due to violations of the migration laws,' Deputy Head of Russia's Federal Migration Service Sverdlovsk Region division Yuri Bezborodov announced at a press conference in Yekaterinburg.
'The foreign workers were forced to leave due to absence of an ID and staying within the Russian borders for a long time without a stay permit. The deportation is enacted through judicial means: a person will either leave Russia of his or her own accord within a given time period or will have to be deported forcefully,' the official explained.
Number of migrant workers halves, Migration Service says
Over 1,800 violations of migration legislation detected in Sverdlovsk Region in two weeks
Foreign workers quotas to go up, Sverdlovsk Region Government says
8,775 people fined for violating foreign workers regulations in Sverdlovsk Region
New law mostly affects foreign workers, says Alexander Biryukov of Federal Migration Service


Protein disulfide isomerases (PDI) are a family of redox chaperones that catalyze formation or isomerization of disulfide bonds in proteins. Previous studies have shown that one member, PDIA3, interacts with influenza A virus (IAV) hemagglutinin (HA), and that this interaction is required for efficient oxidative folding of HA in vitro. However it is unknown whether these host-viral protein interactions occur during active infection and whether this interaction represent a putative target for the treatment of influenza infection. Current therapies targeting viral proteins are often limited in their effectiveness due to rapid development of viral resistance;targeting host proteins may avoid these limitations. Here we show that PDIA3 is specifically upregulated in IAV infected mouse or human lung epithelial cells and PDIA3 directly interacts with IAV-HA. Among PDI inhibitors tested, we found LOC14 inhibits PDIA3 at an IC50 of 5μM. Treatment with LOC14 inhibits PDIA3 activity in lung epithelial cells and subsequently decreases disulfide bonds, and oligomerization (maturation) of HA in both pandemic H1N1 and seasonal H3N2 infected lung epithelial cells. Disulfide labeling analysis indicated that inhibition of PDIA3 activity also decreased disulfide bonds in IAV-neuraminidase (NA) and these differences in oxidative folding correspond to a subsequent decrease in NA activity. Furthermore, these decreases in disulfide bonds significantly decrease viral load, and pro-inflammatory response from primary lung epithelial cells. Lung epithelial specific deletion of PDIA3 in mice results in a significant decreases in viral burden and levels of inflammatory-immune markers in mouse lung, as well as significantly improved airway mechanics (function). Taken together, these results suggest PDIA3 is required for effective influenza pathogenesis in vivo, and inhibition of PDIA3 may aid future development anti-influenza therapies based on inhibition of host PDIs to circumvent antigenic drifts and shifts of influenza and may lend critically needed help during pandemic and severe influenza seasons.


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Cultural › Cultural Center Museum
Educational › Other
Joanthan Wallen Photography, Jonathan Wallen Photography
This children's history museum at the New-York Historical Society transports children ages 8-12 into a world where the history of New York can be explored. The exhibits are created to develop children's research and exploration skills that can be applied to objects from the N-YHS's collection. Visitors become "history sleuths" or detectives and unlock information that makes objects, events and historical persons come to life through the context of the child's life in New York. Visitors will use these new findings to continue discovery and meaning-making beyond the walls of the Society as they experience New York City's streets, parks, public places and infrastructure.
The space is designed as a library of wonderment, full of objects and displays that blur the line between past and present, and that upon closer examination reveal hidden opportunities to delve deeper into the historical context. A bookshelf spins to reveal technology kiosks that allow discovery of historical documents; keyholes focus visitors attention on a historical event; various "decoders" explain handwriting from the past, others aid visitors in developing symbolism and meaning from historical objects and depictions. The gallery also uses people's innate fascination with personal
stories to discover various individuals from New York past, making full use of audio, scents, textures and other sensory elements to immerse visitors in "portraits come to life". The DiMenna Children's History Museum also incorporates the Barbara K. Lipman Children's History Library, an area
where the N-YHS makes its collection of children's books accessible.
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And after taking a stroll around the world, foodwise (I saw this lovely old movie a few nights ago), here I am, back home: back to Italy, with pasta.
Like most Italian people who cook, I often make my own. Fresh pasta is a completely different product from 'regular' dried durum wheat pasta, the one sold in every supermarket; and it is infinitely better than store-bought fresh pasta, unless of course you have a good pastificio artigianale down the road. For these reasons, if you have never eaten it, you really should give this (or any other recipe) a try. Once you learn the basics, it is easy to make: I have tested this on a few friends, who asked me to teach them how to make pasta: they could not believe the sumptuous dish of pappardelle al ragù we produced after a mere couple of hours work.
(It can take less than that, with some experience; it will take more than that, if you make ragù without a pressure cooker).
A constant thought, in these days. I hope Japan will be able to recover soon. And we will be thinking about its fabulous food, cinema, literature, design, technological innovations again, when we think of Japan.
Method: Remove the roots from the spinach but keep all the stalk, and keep them in bundle form as much as possible. Wash in cold water until no grit is left. Bring a wide pan of water to the boil, drop in the spinach, blanch for about a minute and drain. Cool under cold, running water. Squeeze gently with your hand. Have a sushi mat ready. Arrange the spinach neatly on it, with all the stalks on one side. Fold the tips so that the ends will be more even. Roll the sushi mat, press gently with your fingers to get a squarish log. Press well and leave for a while slightly inclined so that the water can run away. When water is no longer dripping off it, put the roll within its sushi mat in the fridge until needed.
For the sauce: if not toasted, toast your sesame seeds: heat a small heavy pan, add the sesame seeds and gently roll the pan until they start to pop. Take care because at this stage they go from toasted to burned in a second.
Put the toasted sesame seeds in a mortar and crush them with a circular movement. Add sugar and crush a bit more; add mirin and soy sauce; taste and adjust the flavours to your liking. It should be definitely sweet, definitely salty and very flavorful. To serve, arrange some sauce on a small dish, cut the spinach log using a sharp knife in two – three pieces, discarding the extremities if they are not neat, and arrange on top of the sauce.


This is a Baked ice cream float – in the style of Baked the bakery, not baked in the oven. And Baked style means there's booze in there instead of plain old root beer. At any rate, it's a good way to finish up a meal. Or replace a meal, if that's your preference.
Simple to make, a standard brown cow is just a root beer float that includes chocolate syrup. Warm cream and good quality chocolate make a quick and delicious chocolate syrup. Top that off with vanilla ice cream, a shot of coffee liqueur (St. George Nola in my case) and a sprinkling of nutmeg, and you've got dessert.
I particularly like how easy it is to mix things up with this, too. I almost used raspberry brandy instead of coffee liqueur. Nocino might be nice as well.


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Cesium desorption from illite as affected by exudates from rhizosphere bacteria
Laura A. Wendling, James B. Harsh, Thomas E. Ward, Carl D. Palmer, Melinda A. Hamilton, Jeffrey S. Boyle, Markus Flury
Not published at VTT
The United States Department of Agriculture
Idaho National Laboratory
Biogeochemical processes in the rhizosphere can significantly alter interactions between contaminants and soil minerals. In this study, several strains of bacteria that exude aluminum (Al)-chelating compounds were isolated from the rhizosphere of crested wheatgrass (Agropyron desertorum) collected from the Idaho National Laboratory (INL). We examined the effects of exudates from bacteria in the genera Bacillus, Halstonia, and Enterobacter on cesium (Cs) desorption from illite. Exudates from these strains of bacteria significantly enhanced Cs desorption from illite. In addition, Cs desorption increased with increasing Bacillus exudate concentrations. Cesium desorption from illite as a function of both exudate type and concentration was positively correlated with Al dissolution, suggesting that the Al-complexing ability of the exudates played an important role in enhancing Cs desorption. The density of frayed edge sites (FES) on illite increased as a result of treatment with bacterial exudates, while the Cs/K selectivity of FES decreased. These results suggest that exudates from bacteria isolated from the rhizosphere can enhance Cs desorption from frayed edges of illite and, therefore, can alter Cs availability in micaceous soils.
https://doi.org/10.1021/es048809p
10.1021/es048809p
Dive into the research topics of 'Cesium desorption from illite as affected by exudates from rhizosphere bacteria'. Together they form a unique fingerprint.
Desorption Chemistry 100%
Caesium Physics 42%
Illite Agricultural and Biological Sciences 28%
Bacteria Physics 23%
Rhizosphere Chemistry 19%
Bacterium Immunology and Microbiology 19%
Exudate Agricultural and Biological Sciences 14%
Aluminium Physics 14%
Wendling, L. A., Harsh, J. B., Ward, T. E., Palmer, C. D., Hamilton, M. A., Boyle, J. S., & Flury, M. (2005). Cesium desorption from illite as affected by exudates from rhizosphere bacteria. Environmental Science & Technology, 39(12), 4505-4512. https://doi.org/10.1021/es048809p
Wendling, Laura A. ; Harsh, James B. ; Ward, Thomas E. et al. / Cesium desorption from illite as affected by exudates from rhizosphere bacteria. In: Environmental Science & Technology. 2005 ; Vol. 39, No. 12. pp. 4505-4512.
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title = "Cesium desorption from illite as affected by exudates from rhizosphere bacteria",
abstract = "Biogeochemical processes in the rhizosphere can significantly alter interactions between contaminants and soil minerals. In this study, several strains of bacteria that exude aluminum (Al)-chelating compounds were isolated from the rhizosphere of crested wheatgrass (Agropyron desertorum) collected from the Idaho National Laboratory (INL). We examined the effects of exudates from bacteria in the genera Bacillus, Halstonia, and Enterobacter on cesium (Cs) desorption from illite. Exudates from these strains of bacteria significantly enhanced Cs desorption from illite. In addition, Cs desorption increased with increasing Bacillus exudate concentrations. Cesium desorption from illite as a function of both exudate type and concentration was positively correlated with Al dissolution, suggesting that the Al-complexing ability of the exudates played an important role in enhancing Cs desorption. The density of frayed edge sites (FES) on illite increased as a result of treatment with bacterial exudates, while the Cs/K selectivity of FES decreased. These results suggest that exudates from bacteria isolated from the rhizosphere can enhance Cs desorption from frayed edges of illite and, therefore, can alter Cs availability in micaceous soils.",
author = "Wendling, {Laura A.} and Harsh, {James B.} and Ward, {Thomas E.} and Palmer, {Carl D.} and Hamilton, {Melinda A.} and Boyle, {Jeffrey S.} and Markus Flury",
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journal = "Environmental Science & Technology",
publisher = "American Chemical Society ACS",
Wendling, LA, Harsh, JB, Ward, TE, Palmer, CD, Hamilton, MA, Boyle, JS & Flury, M 2005, 'Cesium desorption from illite as affected by exudates from rhizosphere bacteria', Environmental Science & Technology, vol. 39, no. 12, pp. 4505-4512. https://doi.org/10.1021/es048809p
Cesium desorption from illite as affected by exudates from rhizosphere bacteria. / Wendling, Laura A.; Harsh, James B.; Ward, Thomas E. et al.
In: Environmental Science & Technology, Vol. 39, No. 12, 15.06.2005, p. 4505-4512.
T1 - Cesium desorption from illite as affected by exudates from rhizosphere bacteria
AU - Wendling, Laura A.
AU - Harsh, James B.
AU - Ward, Thomas E.
AU - Palmer, Carl D.
AU - Hamilton, Melinda A.
AU - Boyle, Jeffrey S.
AU - Flury, Markus
N2 - Biogeochemical processes in the rhizosphere can significantly alter interactions between contaminants and soil minerals. In this study, several strains of bacteria that exude aluminum (Al)-chelating compounds were isolated from the rhizosphere of crested wheatgrass (Agropyron desertorum) collected from the Idaho National Laboratory (INL). We examined the effects of exudates from bacteria in the genera Bacillus, Halstonia, and Enterobacter on cesium (Cs) desorption from illite. Exudates from these strains of bacteria significantly enhanced Cs desorption from illite. In addition, Cs desorption increased with increasing Bacillus exudate concentrations. Cesium desorption from illite as a function of both exudate type and concentration was positively correlated with Al dissolution, suggesting that the Al-complexing ability of the exudates played an important role in enhancing Cs desorption. The density of frayed edge sites (FES) on illite increased as a result of treatment with bacterial exudates, while the Cs/K selectivity of FES decreased. These results suggest that exudates from bacteria isolated from the rhizosphere can enhance Cs desorption from frayed edges of illite and, therefore, can alter Cs availability in micaceous soils.
AB - Biogeochemical processes in the rhizosphere can significantly alter interactions between contaminants and soil minerals. In this study, several strains of bacteria that exude aluminum (Al)-chelating compounds were isolated from the rhizosphere of crested wheatgrass (Agropyron desertorum) collected from the Idaho National Laboratory (INL). We examined the effects of exudates from bacteria in the genera Bacillus, Halstonia, and Enterobacter on cesium (Cs) desorption from illite. Exudates from these strains of bacteria significantly enhanced Cs desorption from illite. In addition, Cs desorption increased with increasing Bacillus exudate concentrations. Cesium desorption from illite as a function of both exudate type and concentration was positively correlated with Al dissolution, suggesting that the Al-complexing ability of the exudates played an important role in enhancing Cs desorption. The density of frayed edge sites (FES) on illite increased as a result of treatment with bacterial exudates, while the Cs/K selectivity of FES decreased. These results suggest that exudates from bacteria isolated from the rhizosphere can enhance Cs desorption from frayed edges of illite and, therefore, can alter Cs availability in micaceous soils.
U2 - 10.1021/es048809p
DO - 10.1021/es048809p
JO - Environmental Science & Technology
JF - Environmental Science & Technology
Wendling LA, Harsh JB, Ward TE, Palmer CD, Hamilton MA, Boyle JS et al. Cesium desorption from illite as affected by exudates from rhizosphere bacteria. Environmental Science & Technology. 2005 Jun 15;39(12):4505-4512. doi: 10.1021/es048809p


text:
Lewis Hamilton Closes on to World Title After Japanese Gp Win
by Arunesh Varade on October 9, 2017
After grabbing his first ever pole position in Japan, Lewis Hamilton put up a scintillating display to clinch Japanese GP in Suzuka. Following this win, the Mercedes driver closes on to the fourth world title. The Briton dominated from pole, steering to a crushing eighth win of the year. Extending his F1 championship lead over Vettel to 59 points with just 100 left to play for.
A dominant Lewis Hamilton
Hamilton completed his collection of a pole position at every current Formula One circuit with a record lap in Suzuka on Saturday. Even though he had secured the top slot at Fuji in 2007, he can look forward to a new sensation.
I've never really had this view here.
The 32-year-old said on the starting grid after qualifying. He further added
It's incredible for me. 10 years or whatever it is, my first pole position here. Tenth time lucky, so I'm grateful for that.
As the qualifications went by, the Briton topped it out with a lap of 1 minute 27.319 seconds securing him the first spot.
Race moments
Starting off strongly, Lewis maintained his lead throughout the 53 lap race to sail home comfortably. As a result, he amassed 306 points to top the F1 Driver's Championship of 2017.
As Hamilton won his fourth title in Japan, Vettel's title hope suffered a huge blow. Not only it was a nightmare start for the Ferrari driver, but now only four races remain to build up to the championship.
Japenese Grand Prix round-up
After Hamilton, the Red Bulls of Verstappen and Daniel Ricciardo secured a double podium for the second successive race. Next up, Valtteri Bottas finished fourth with Kimi Raikkonen's Ferrari taking fifth.
Hamilton after the Japanese GP win
It was the Force India duo of Esteban Ocon and Sergio Perez finishing sixth and seventh respectively. Following them were two cars of Haas driven by Kevin Magnussen and Romain Grosjean. Felipe Massa held on to Fernando Alonso's McLaren to take 10th for Williams.
Arunesh Varade
I am an enthusiastic individual with a passion for writing. I am an Engineer. Ambivert. Creative. I love watching Cricket and badminton.Sport is fun. Get on the run!


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Sweeney Todd Musical Production
by Millie Hoekstra | Jan 7, 2020
The Demon Barber of Fleet Street
A Musical Thriller
Community Musical Theater Production
July 1, 2, 4, 5, 2021
Showtimes: 7 PM except on Sunday, July 4, which is a 4 PM Matinee
One of the darkest musicals ever written, Sweeney Todd: A Musical Thriller, is the unsettling tale of a Victorian-era barber who returns home to London after fifteen years of exile to take revenge on the corrupt judge who ruined his life. When revenge eludes him, Sweeney swears vengeance on the entire human race, murdering as many people as he can, while his business associate Mrs. Lovett bakes the bodies into meat pies and sells them to the unsuspecting public. Perhaps composer/lyricist Stephen Sondheim's most perfect score, Sweeney Todd is lush, operatic, and full of soaring beauty, pitch-black comedy and stunning terror. It's one of the signal achievements of the American musical theater of the last fifty years, and it's the high water mark of Sondheim's six remarkable collaborations with director Harold Prince. – StageAgent.com
Admission: Reserved Seating – Adults: $20/*First-Night (7/1) and Matinee (7/4): $15, Youth (18 & under) all shows: $10
To reserve your seats, click HERE to reserve your tickets online or call the Box Office at 207-864-5000 Mon thru Thurs 10-2. Tickets will also be available at the door.
Sweeney Todd is presented through special arrangement with Music Theater International (MTI). All authorized performance materials are also supplied by MTI. www.MTIShows.com
*First-Night: an opening night ticket discount to showcase the performers and reward our wonderfully supportive community that enjoys RFA's live theater productions.


text:
Trump's team so far: Very rich, very conservative and, mostly, very loyal | iNFOnews | Thompson-Okanagan's News Source
Trump's team so far: Very rich, very conservative and, mostly, very loyal
Alexander Panetta
President-elect Donald Trump, left, and Vice President-elect Mike Pence arrive at Indianapolis International Airport for visit to the Carrier factory, Thursday, Dec. 1, 2016, in Indianapolis, Ind.
Image Credit: AP Photo/Evan Vucci
WASHINGTON - Donald Trump has now appointed almost half his cabinet, which allows for some tea-leaf-reading about the team that will surround him when he takes office on Jan. 20.
Here's what we know so far. Trump's team is:
The Washington Post began a story noting that George W. Bush's cabinet was called the team of millionaires, then added: "Combined, that group had (a)... net worth of about $250 million — which is roughly one-10th the wealth of Donald Trump's nominee for commerce secretary alone."
That's Wilbur Ross, the billionaire investor. Trump's team includes heirs to the Ameritrade and Amway fortunes, one of whom, Todd Ricketts, also owns the Chicago Cubs baseball team.
Then there's the next transportation secretary — a member of the U.S.'s 39th-richest family, according to Forbes. Elaine Chao, a former cabinet member, is also the daughter of a shipping magnate.
The next Treasury secretary is a relative pauper, compared to these people. Hedge-fund manager Steve Mnuchin is reportedly worth a mere $40 million.
"Almost no one going into this administration... isn't making an economic sacrifice, big-time, in order to do so," Ross told CNN this week.
"We want to give back and help the country," Ross said.
—Quite conservative
Trump is only occasionally a conservative. Some members of his team are true believers.
That includes the billionaire picked for education secretary. Betsy DeVos is a leading proponent of alternatives to public schools, in the use of vouchers and privately run institutions.
The pick for health secretary, Tom Price, has advocated a more laissez-faire approach than Obamacare.
The attorney general pick, Jeff Sessions, has fought against the national, bipartisan-supported trend of relaxing drug penalties. He'll now run the Justice Department, if he's confirmed by his Senate colleagues. Sessions has criticized sentencing reform, fought federal voting-rights policies, and recently said this about marijuana:
"This drug is dangerous, you cannot play with it, it is not funny, it's not something to laugh about... good people don't smoke marijuana."
The vice-president-elect, Mike Pence, once supported federal funding for gay-conversion therapy — though he's never called for it. Trump, himself, has suggested he'll appoint pro-life judges, oppose gun control, and scale back climate regulations.
—Not devoid of Democrats
Not everyone is a died-in-the-wool conservative. The commerce pick, Ross, used to be a Democrat and donated in the 1990s to Bill Clinton and senators Ted Kennedy and Sam Nunn. He flipped to the Republicans in the early 2000s, and generally favours deregulation. Former general Michael Flynn also was a Democrat.
In fact, much of Trump's family fits that description. Politico reports his daughter, Ivanka, intends to play a First Lady-like role and champion climate change causes, after already having pushed her father to announce plans for a parental-leave program.
Trump has also been meeting with some Democrats during the transition.
—Led by campaign allies — mostly
The top White House staffers will be fellow travellers from Trump's campaign — Republican chair Reince Priebus and strategist Steve Bannon. The commerce secretary, Ross, wrote Trump's anti-NAFTA trade platform.
The Treasury nominee shocked Wall Street friends earlier this year by coming out as a Trump adviser on tax policy. Mnuchin was quoted replying in one report: "Nobody's going to be like, 'Well, why did he do this?' if I end up in the administration."
His intuition proved correct.
Other loyalists include the attorney-general nominee. Sessions was the first senator to support Trump. The national security adviser, Michael Flynn, was his earliest prominent adviser on defence issues.
However, Trump has gone outside the tent.
He's appointed former critic Nikki Haley, the governor of South Carolina, as UN ambassador. He's meeting Mitt Romney and former general David Petraeus for the secretary of state job, to the chagrin of loyalists like Rudy Giuliani.
—A potential generals' club
Trump has appointed Flynn to advise him on national security. He's been considering ex-general James Mattis for defence secretary. Petraeus is in the running for secretary of state. On Friday, Trump meets retired Rear Admiral Jay Cohen.
—Going to have racial controversies
At his Senate confirmation hearing, Sessions will certainly be asked about his last confirmation hearing, three decades ago. The chamber refused to make him a federal judge because of remarks about blacks, including one possible joke about supporting the Ku Klux Klan.
He's an ardent foe of undocumented immigrants, and supports voter-ID and justice policies that disproportionately affect blacks.
Flynn has often made disparaging remarks about Islam. In one speech, he described the religion as "a vicious cancer inside the body of 1.7 billion people" that must be "excised."
—Intent on reforming NAFTA
Trump's Commerce pick suggests he intends to revamp NAFTA, as promised. Ross helped write that promise. The billionaire has invested in struggling manufacturing companies, and says the U.S. would have more if it fought foreign sales-tax policies — which he says are designed to force U.S. companies to relocate.
Ross has heralded it an early priority: "We're working out the fine-point details, but NAFTA is a logical starting point," he told CNN.


text:
Luminescent nanoparticles help with early cancer detection
Walking in the model of an intestine: International research teams have developed fluorescent nanoparticles to detect cancer cells at an early stage. Credit: Felix Burda Foundation
In a project funded by the FWF, a research group from Innsbruck investigated how cancer cells in the large intestine can be made to glow in order to facilitate early detection.
Colorectal carcinoma (CRC) is one of the deadliest cancers, and it is the second most common type of cancer in Europe. CRC can be treated well in the early stages and the developing tumour can easily be removed. In most cases, however, the cancer is discovered at a very late stage, when the treatment is already very difficult. This is why there are international recommendations for a screening regime from the age of 50, with screenings every five years. During the colonoscopy, every square centimetre of the colon is examined for tumours, and dangerous tissue is removed immediately. Even so, some of the small tumours are not detected, which often has dramatic consequences, especially if this examination is not carried out regularly. Within the context of the EU's NanoEFEct project and with support from the Austrian Science Fund FWF, a research group led by the biologist Paul Debbage from the Medical University of Innsbruck has now investigated ways of labelling cancer cells with luminous substances to make them more easily visible during screening.
Cancer not detected at an early stage
"Colorectal cancer screening is actually a very good preventative approach", says Debbage, "but there is a gap because a small percentage of carcinoma is not detected." Under the lead of principal investigator Debbage, research teams in Portugal, Norway and Innsbruck set out to close this gap by developing fluorescent nanoparticles designed to bind to the cell membranes of cancer cells. The nanoparticles are much larger than the protein molecules of the cells, but many times smaller than the cells themselves. "The Innsbruck team's nanoparticles had a diameter of 30 nanometres." That is between 500 and 5,000 times thinner than a human hair. At this scale, quantum physics effects are already occurring, notes the researcher: "There are many effects here that we do not see in the normal world." Because of the quantum effects, the nanoparticles are very bright, which is important, as Debbage underlines: "During a colonoscopy, the physician who carries out the examination sees a pink world. In this world, the cancer cells need to be brightly lit in order to make early stages of cancer easily detectable."
Nanoparticles from building blocks of the human body
Gudrun Thurner, a long-standing member of the Innsbruck group, explains the approach chosen in Innsbruck: "Our nanoparticles are based on a component of the blood serum. They carry a dye on one side and an antibody of the immune system on the other." Antibodies can recognise certain protein structures in order to eliminate pathogens in the body. The antibodies used in this particular case are designed to recognise a certain protein in the cell membrane of the cancer cells and bind to it. "This means that our nanoparticles consist mainly of human components, and only a tiny part - the antibody - is of animal origin. This reduces the risk that the nanoparticle or its components could have a toxic effect on the human body."
In the context of nanoparticles, this question of toxicity is not trivial, because nanoparticles that enter the blood stream could cause damage in a number of different organs. If they are composed mainly of human material, they have a better chance of meeting the approval requirements, which are very complex and time-consuming. Thurner emphasises that Innsbruck's 30 nanometre particles are the perfect size to be incorporated into cancer cells. "We have also invested a great deal of know-how to ensure that the antibody is perfectly aligned with the particle to ensure it fulfils its binding function. In addition, the nanoparticle is designed in such a way that it cannot decompose in the intestine." Gudrun Thurner has thus specialized in a "human material" approach, while the team in Portugal works with gold nanoparticles and the team in Norway with plastic nanoparticles. All three teams succeeded in demonstrating on mice that their method works.
Difficult implementation
Debbage is satisfied with the outcome of this international basic research project, since proof of the effectiveness of the method has been delivered. The difficulty now resides in practical implementation. "Nanoparticles are as complex as small machinery. Toxicity testing is a legal prerequisite, and rightly so." That is a very expensive undertaking - Debbage speaks of several million euros. "At this point we are not at all clear about how this method will ultimately be implemented", notes the researcher. As a state-run research institution usually focusing on research for the oil industry, the Norwegian group has access to funding and will develop the method further. "We would like to develop the Innsbruck method further, but this requires appropriate (seed) funding."
In addition to the groups from Innsbruck, Portugal and Norway, the project had two more partners: the Erlangen Clinic for Gastroenterology, which has access to a collection of cancer preparations and has investigated colon cancer in mice, and the Vienna-based research association CESAR, which contributed its experience with clinical cancer trials.
General access
Debbage emphasises that this method developed by NanoEFEct could be used for a wide range of applications involving cancer: "It could also be used for cancer of the skin, nose, stomach or lung cancer" - i.e. quite generally for types of cancer that are externally accessible. Nanoparticles can be used to reach them without the need to introduce them into the bloodstream. "There's an increasing reluctance to inject substances into the bloodstream", says Debbage.
cancer detection
fluorescent nanoparticles


text:
How Much Is Paramount Plus On Prime 2023
Paramount+ is an on-demand and live TV streaming service …How Much Is Paramount Plus On Prime…where you'll find all of your favorite CBS television programs and movies, including Star Trek: Picard, NCIS, Blue Bloods, and Survivor.
However the home entertainment doesn't stop there. You'll also discover some of your preferred BET, Funny Central, MTV, and Nickelodeon series and movies, too!
And you'll only have to spending plan $5–$ 10 per month for this home entertainment on the go. That's not bad for whatever you get with this service.
If it's worth your time, let's get into the details of this streaming service to find out.
Paramount+ has 30,000+ hours of content with both plans.
This streaming app has a few live television channels (news and NFL games).
The regular monthly cost is low.
Some television programs don't include all episodes in the library.
Paramount+ channels aren't readily available everywhere.
You can see Sunday afternoon NFL football video games on Paramount+ with your household on your wise TV, on your smartphone while awaiting your Lyft, or on your tablet while you're operating on the treadmill.
Paramount+ consists of 6 different types of programs, including:. How Much Is Paramount Plus On Prime
Live television channels (regional, news, and live sports).
Episodes of current CBS network programs (Big Brother, Love Island, Ghosts, and Area).
Episodes of classic CBS programs (The Brady Bunch, Cheers, and Frasier).
BET, Funny Central, MTV, Nickelodeon, and Smithsonian Channel television series and movies (Ridiculousness, Tosh.O, and Spongebob Square Trousers).
Original programming (Star Trek: Strange New Worlds, The Offer, 1883, and Seal Team).
On-demand motion pictures (The Godfather, Paw Patrol: The Movies, Scream, and Grease).
Paramount+ assures 30,000 TV episodes and motion pictures for your on-demand home entertainment.
Paramount+ began its life in the United States back in 2014, as CBS All Access, called after the popular American television network. Back then, it mainly depended on material from the large CBS library– and a couple of early originals like The Good Fight and Star Trek: Discovery.
Betterhelp Pre-treatment – Get Happy
How To Know If My University Has Access Code To Grammarly – Best Discount 98%


I am a passionate ship watcher and I try to photograph as many different ships as possible. I have been doing this for many years and have built up a very large collection. I thought it would be useful to share my locations with others who would be interested in visiting them to get their own pictures. You have to be very patient to get the best pictures of the most interesting ships.
The Lions Gate Bridge is the very best location for ship photography. I go on to the Lions Gate Bridge walkway which has 4 viewing platforms. You can see the sidewalks on both sides of the bridge. At the tower are the two viewing platforms. The one on the right is where I go to photograph. I usually go to the one on the east side looking towards downtown. I am close there to the Park and the ships come very close there too.
A lot people go to the east side of the bridge to see the cruise ships leave for Alaska. I usually photograph there from 3:00 pm to 6:00 pm during which time usually there are a lot of ships which are going in or out of the harbour depending on what is happening.
On the north arm of the Fraser River this is the Outflow Station at No.4 Road at River Road in Richmond BC. You can see that it has viewing platform on which there are stairs on the other side and a bench below it.
Prospect Point in Stanley Park is accessed by the roads in the Park. To get there go to Pipeline Road then at the end make a left and go to the top of the hill where you see the Prospect Point Cafe. That is where a viewing platform is located which was built in 2006 after the December wind storm. The ships come very close there. I usually go there from about 11:00am to 3:00pm.
The Canada Line Bridge has a sidewalk on the west side – it's the only sidewalk on the bridge. It faces towards the airport (YVR) and the Oak Street Bridge. Mainly what you can see are tugs going upbound on the North Arm of the Fraser River but you will see them going outbound too. The bridge is at the end of Cambie Street at east Kent Avenue in Vancouver. I have never seen any other photographers there.
In Richmond I often go to MacDonald Park. The tugs come very close there, and its just across from the airport.


A no-brainer if you like offal, pasta, meat, soup, salumi, salads, seafood, antipasto, olives……oh hang on. They've got food, is my point. But it is fabulous, authentic Italian food, not to be confused with dead Southbank food. The spaghetti arrabbiata baked in a bag with crab, tomato and chilli is the hands down favourite for many. For the rest of us, it's the bistecca fiorentina, an 800 gram T-bone Angus monster served with salsa erbe and spuds. Perfectly quaffable house plonk comes in carafes, a lovely long-lost tradition. The fresh raspberry, rose-flavoured grappa and vanilla mascarpone tart is a stunner of a finale.
GAS is another one of those restaurants where lighting is dimmed to the point of non-existence, but it somehow works for this Italian dame and her provocative display of of hung salumi.
Posted in Lovely Lunch, Posh Nosh.Link.


Yes, you are a skilled dentist. But, are you a skilled entrepreneur? I teach dentists how to develop skills in running a successful business that keeps customers coming back.
Dental clinic marketing is extremely competitve on Google, Facebook, Instagram, Yelp, and more. Let me audit your online marketing efforts and boost your visibility.
I can turn your existing dentist office staff into an awesome, patient-focused team that gets appointments scheduled, bills paid, and patients returning.
...is to do it now.
I see your schedule fully booked. I see co-pays being collected at the time of visit. I see new patients being referred by existing patients. I see a cohesive, enthusiastic team. I'm here to make your dental office awesome, not just to make it better.
An eager entrepreneur, with a passion for dentistry and drive for success. Coaching dentists to align the vision of their business is something that stemmed from my career in the industry and my own success in building a brand and business. I know that dentistry has its challenges, but no more than any other business out there. It is my goal, my calling if you will, to partner the love I have for dentistry, with my flare for business and to assist dentists in building profitable, fun, long-standing dental practices.
The best way to describe Sina is a whirlwind. She works fast, and likes to be productive. I appreciated her attention to detail, compassion for our patients and willingness to take care of our team. Working as a team, we were able to bring our revenue up considerably, have a full hygiene schedule on a consistent basis and patients scheduling and completing treatment. Sina brings an element of creativity and fun to the dental office, which makes the patient and team experience one that people want to be part of. It is hard to not get excited about business and the potential when you talk with Sina. She likes to be successful, but thrives on the success of others.
Sina is motivated and passionate about what she does. She values teamwork, understands the importance of service and has valuable skills in leadership, marketing and overall business.
With Sina's leadership, success always followed. Sina has a way of working with people that shows she genuinely cares for the greater good of all involved.
I worked with Sina for a year. Her leadership and organization skills were paramount to our success as a team. She would be a valuable asset to any dental practice.
Sina is a true leader, one that if you have the chance to work with, you have to get her on your team.
Sina knows leadership. She cares about who she works with. Her creativity for business and customer skills are one's people need in their business. If I could, I would work with her again!


text:
Q: Is Gower's Distance a metric? A novice here
My previous question was closed due to inadequate details
So here I've added more details
A metric should basically satisfy 3 properties

*

*Distance is equal to zero if and only if $x$ is equal to $y$ ($d(x,y)=0 ⇔ x=y$))

*Distance from $x$ to $y$ is the same as distance from $y$ to $x$ ($d(x,y)=d(y,x)$)

*Distance should satisfy the triangular inequality ($d(x,y)\leq d(x,z) +d(z,y)$)

I already know that Gower's distance satisfy the first 2 properties to be a metric, but I want to know whether it satisfies the triangular inequality property.
The reason I want to know this, is because all metric spaces are Hausdorff spaces, and I want use the Gowers distance in order to find the Hausdorff distance for 2 sets of points.
In my case, a point contains data of mixed types (logical, categorical & numeral), and therefore I have to use the Gowers distance.
Any help would be appreciated.
Thank You!
Edit:
According to a suggestion on the comments, here is the formal definition of a metric
A metric on a set X is a function (called the distance function or simply distance)
$d : X × X → R$
(where R is the set of real numbers). For all $ x, y, z $ in $X$, this function is required to satisfy the following conditions:

*

*$d(x, y) ≥ 0$ (non-negativity)

*$d(x, y) = 0$   if and only if   $x = y $

*$d(x, y) = d(y, x) $    (symmetry)

*$d(x, z) ≤ d(x, y) + d(y, z) $
Note that the first condition is implied by the others.

A: Referring to the answer in https://stats.stackexchange.com/questions/15287/hierarchical-clustering-with-mixed-type-data-what-distance-similarity-to-use
"Gower distance". Without ordinal variables present (i.e. w/o using the Podani's option) √1−GS behaves as Euclidean distance, it fully supports euclidean space. But 1−GS is only metric (supports triangular inequality), not Euclidean. With ordinal variables present (using the Podani's option) √1−GS is only metric, not Euclidean; and 1−GS isn't metric at all."
Therefore it can be used a metric

Papers
1 Gower J. C. A general coefficient of similarity and some of its properties // Biometrics, 1971, 27, 857-872
2 Podani, J. Extending Gower's general coefficient of similarity to ordinal characters // Taxon, 1999, 48, 331-340

redpajama_set_name: RedPajamaStackExchange


look back at the growing season of 2009.
It was strange and unpredictable.
started and didn't seem to conclude until the end of May.
In Durango, our last spring frost in 2009 was technically May 1, which is very early. Our first fall frost was Sept.
22 (normal), giving us a growing season of 144 days. But if you were brave enough to plant tender vegetables in May, then I don't think I would want to play poker with you.
plants in the ground, they didn't really seem excited about growing.
degrees. Those are the 14 days of the year I wish I had air conditioning.
To top it all off, during the second week of August we had a cold snap where temperatures dipped into the upper 30s, and in some locations around the area, a light frost was reported.
makes growing fruits and vegetables in our area so difficult.
edible crops, then pay attention to what is going on in your backyard.
season of 2010. Contact me if you are interested.


The Super Bowl matchup between the New England Patriots and the Los Angeles Rams takes place this Sunday, February 3, at Mercedes-Benz Stadium in Atlanta.
People across the world will be gathering at Super Bowl parties to watch the game and enjoy the festivities surrounding the event.
Regardless of who you are rooting for, make sure that you show up to your party dressed to impress by getting some official Super Bowl gear before Sunday from the online NFL Shop.
While only two teams play in the Super Bowl, the game itself is watched by millions of people all across the country.
Super Bowl parties have become their own event, with people gorging on infinitely layered dips, Olympic swimming pools of guacamole, and dangerous amounts chicken wings. Plus, because gambling is now an inherent aspect of watching sports, squares boards and prop bets are now commonplace at the parties, making the on-field spectacle must-see TV.
New England fans should have already budgeted funds for division and conference championship shirts, hats, and hoodies at the beginning of the season, while Los Angeles devotees should capitalize on their moment, because, as you know, one bad call and your dreams can vanish quicker than the velocity of a Gronk Spike.
Be the one who turn heads at your Super Bowl party by rocking some of this official gear from the NFL Shop; just make sure you don't spill any buffalo sauce on it.
This team gear should arrive in time for the big game if you order before the end of the day on Thursday, January 31.
Stay neutral and celebrate the game with this long-sleeve T-shirt.
If you don't have a horse in this race, but still want to feel festive, there are plenty of neutral Super Bowl-themed shirts you can don.
Don a New England Patriots AFC conference championship T-shirt.
If you're a Patriots fan, add to your collection and celebrate New England's annoyingly awesome dominance with this official AFC Champions T-shirt from the NFL Pro Line by Fanatics Branded.
Keep your head in the game with this Super Bowl snapback.
Make sure this year's game and team remains special in your mind with this official Super Bowl LIII embroidered snapback hat.
Win or lose, this shirt is perfect for Boston transplants across the country.
Regardless of where you rest your head at night, if you are a Boston fan, you have plenty of reason to be proud this year. The Red Sox are the reigning champions in the MLB, the Celtics are one of the frontrunners in the NBA, and the Boston Bruins have a solid chance of making the NHL playoffs. Just one of those feats would be enough to keep most cities' fans pleased with the state of their sports for half a decade. Make sure that people know you represent the city of champions with this Hometown Slogan T-Shirt from Fanatics.
Start their fandom from birth with this championship onesie.
While 33-year-old Rams head coach Sean McVay may be considered young for a typical NFL coach, there are plenty of real infants that will be plopped in front of a TV to enjoy the game this Sunday. This may be your Rams baby's only shot to "watch" their team in the Super Bowl, so make sure they are suited up in team gear.
Keep warm in this knit winter hat.
Los Angeles is known for its temperate climate, but there are Rams fans spread across the US who want to simultaneously represent their favorite team and protect their ears from the dangerously frigid temperatures. The official Super Bowl logo and team logos are embroidered on this knit hat, so everyone will know who you're rooting for in the big game.
Embody the NFL's version of Thanos with this official team jersey.
Aaron Donald is legitimately an unfair weapon for an NFL team to have on their defense. The unblockable man who is commonly compared to Thanos is a jaw-dropping talent who hopes to get close and personal with Tom Brady throughout Sunday's game. Embody the spirit of the NFL's most impactful defensive player by rocking his official Super Bowl jersey from Nike.
Be part of the game with this official game coin.
After the conference championships ended and coin flip-gate became a widely discussed talking point for every major sports media outlet, it is unclear whether or not the game's most exciting moment will be a part of the sport in the near future. In all seriousness, the coin flip is something that has been happening in football for decades, and if this really is the last time it impacts a playoff game, it's totally worth splurging for this memorabilia to remember the times when a flick of the thumb potentially determined a Super Bowl championship.
Play like the pros with the official game football used in Super Bowl LIII.
This football with the Super Bowl LIII logo embroidered on it is a great decorative piece to add to your home or office.


text:
DFT Study on Amino-Phospholipids Surface Mediated Decomposition of Hydrogen Peroxide
Solís Calero, Christian; Ortega Castro, Joaquín; Muñoz Izquierdo, Francisco
[eng] Hydrogen peroxide molecules play a significant role in controlling certain cellular functions, and its excess causes significant damage to biological systems. There is experimental evidence that its decomposition is accelerated above phospholipids membranes surface. We propose a mechanism for decomposition of hydrogen peroxide on amino-phospholipids surface model based in Dmol3/DFT calculations. The model was built using periodic boundary conditions. Each unit cell contained two phospholipids molecules, two hydrogen peroxide molecules, and nine water molecules. In the studied reaction, two hydrogen peroxide molecules react in a bimolecular reaction to yield an oxygen molecule and two waters. The reaction proceeds by two steps. In the first step, an intermediate hydrogen trioxide from two H2O2 molecules is formed. In the second step, this intermediate is cleaved in O2 and H2O. There are proton exchanges along the interface between water and amine-phospholipids monolayer in all parts of the pathway. A parallel periodic model of pure water was built to compare the free energy variation through the reaction. Our results show that first step, intermediate hydrogen trioxide formation, is the limiting step of the reaction, having a free energy barrier of 8.76 kcal mol
1 in the amino-phospholipids surface model and 25.56 kcal mol
1 in the case of pure water model. It could be hypothesized that cell membrane surface environment could enhance this reaction by a neighboring catalyst effect.


Kyiv, Ukraine – This Winter almost 100 kids and counselors are hoping to attend the annual Mercy Projects Winter Camp.
December 31 – January 8, 2019 Winter Camp Ukraine. Call Zach for details at Mercy Projects in California 951.696.5244 or go to www.mercyprojects.org.