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Home / Shop / Guns / Springfield Armory Hellcat
Springfield Armory Hellcat
Looking for a powerful new 9mm handgun? Look no further than the Springfield Armory Hellcat. This sleek and stylish handgun is built with quality and performance in mind, and features a 3″ hammer forged steel barrel, 1:10 slide ratio, and black polymer frame with an adaptive grip texture. The Tritium/luminescent front sight and tactical rack U-notch rear sight make aiming easy, while the dual recoil springs provide plenty of resiliency. The 11-round and 13-round extended magazines provide plenty of ammo, and the lightweight 17.9 oz weight with flush mag or 18.3 oz weight with extended mag makes for easy carry and recoil control. Whether you're a first time buyer or a seasoned professional, the Springfield Armory Hellcat is sure to please.
Category: Guns
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High capacity magazine.
Great grip.
Odd trigger.
Snappy recoil.
Springfield Armory Hellcat History & Origins
We think Springfield Armory would agree that the Hellcat represents their response to the Sig p365, which completely rethought the possibilities for a concealed carry pistol.
Similar to the Hellion, the Hellcat is a Croatian-made import. Since around 2003, Springfield has been distributing firearms that they acquire by HS Produkt in Croatia. Initially, they were importing the XD line of pistols, which provided a fair value for a respectable handgun.
We see a pattern here: after releasing the Hellion bull-pup rifle, they are now releasing the Hellcat handgun. The CDs were satisfactory, but the new material is much better.
Just pick up a Hellcat and you'll see what we mean; they've made a lot of improvements, and now, the Hellcat is a formidable opponent.
The Hellcat offers a high-capacity micro 9mm pistol. With a flush magazine, it can store 11+1 9mm rounds, and with an extended magazine, it can hold 13+1 rounds.
Key Features of the Hellcat
Even though there isn't currently a way to attach an external safety to the Springfield Hellcat Pro, we fully expect there to be one available in the near future.
What they've done with the exterior safety, for this entire line, has impressed us greatly, and we have no doubt that the Pro will do the same.
The gun's back features an ambidextrous, low-profile thumb safety mount that's big enough to rest your thumb while firing.
As a result, the gun's safety can be adjusted just as easily as on a compact 1911.
Others have claimed that the trigger is superior to that of a Glock. It's hard for us to determine whether or not it's better, but it has noticeably shorter recoil and sharper trigger pull than a Glock. The Hellcat and Glock have similar triggers, in our opinion, but let us know if you feel differently.
Also, the reset is too loud and too tactile for my taste.
The sights on this concealed carry handgun are excellent. We were not a full fan of the sights before we fired the Hellcat, but then we came to appreciate how simple Springfield made it to keep the sights steady.
Additionally, red-dot sights are unquestionably the way forward for handguns. It's awesome that the company is releasing an optics-ready model simultaneously with the pistol.
How Does The Hellcat Perform?
The gun's portability and manageability make it ideal for carrying concealed. It's not going to win any awards as a performance pistol, but it fires reliably. You could improve your accuracy, but it would slow you down, if you used smaller, more conventional sights.
We put the Hellcat through two days of testing. The weapon functioned flawlessly from standard shooting positions regardless of the load or bullet weight in the magazine.
The only problem we had was when practicing firing in close quarters just at moment where the handgun clears the holster, and the slide jammed back after we fired it.
To our hands, the Hellcat feels like a natural extension of our own body. Having the serrations on the back of the slide is also great. Also, the red dot attachment is a nice addition, this feature is useful even if you don't plan on purchasing one.
Taking your Hellcat to the range? You'll love the serrated slide's improved grip. The handgun is so small that even the pistol grip wouldn't be enough to maintain a stable aim without the serrations, so shooting Hellcat is a bit of a chore.
Lightweight is another strength of the Hellcat. The handgun weighs only about 18 ounces, depending on how many rounds are in the magazine, so you won't even notice you're carrying one. Because of its light frame, this handgun is perfect for daily concealed carry due to its ease of use and manageability.
CZ 75 SP01


"Get the best Aboriginal experiences"
Aboriginal Australia is something you should try to incorporate into your trip.
The word aborigine or aboriginal means Indigenous to Australia. They were the original inhabiters of Australia before the island was discovered and occupied by the British and other Europeans.
It's difficult to say when exactly the first aborigine settler can be traced back to but some experts believe it could be as many as 50,000 years ago.
Pre 1788 when the European settlement started, the aboriginal Australia population was probably around 315,000. They were semi-nomadic hunter gatherers. That meant that they moved around a little bit to ensure they got enough food, but they lived off the land.
There were 250 different nations each with their own customs, language and clans. So, there were over 200 languages, many of which are extinct today. These nations were spread right across Australia but the east and southern regions were the most densely populated.
With the European settlers came old world diseases that the aborigines could not survive. This wiped out many of their population. On top of that, laws gave them no claim to the land and as the European settlers grew, the aborgines were pushed out.
The stolen generations refers to aboriginal Australia children who were removed from their homes by the Australian state government from 1869 to 1969 - although it is believed that this may have continued into the 1970's. The prime minister Kevin Rudd, offered an official apology in 2008.
These days, the aboriginals account for just 3% of the Australian population and are more likely to suffer with alcohol problems and have poor health.
Has this inspired you to find your own roots? Understand where you come from? If so, why not start tracing your own family history.
Aboriginals have a belief system known as the dreamtime or dreaming. They believe that there are two parallel streams of activity. One is the day to day activities , the other is the "dreamtime", and is very spiritual.
Whatever happens in this dreamtime establishes the values, symbols, and laws of their society. This is how stories and ancient beliefs have developed about plants, animals and places. As such there are certain places that are very sacred to their people. Ayers Rock for example is one such place. PLEASE don't climb the rock out of respect for their customs.
Music and Art remain two of the most well known aspects to the aborigine culture. Whilst the didgeridoo is probably the most well known, this instrument only really originates from the Eastern part of Australia. The clapping sticks, which help keep the rhythm, are more widely used.
Now the tradition is continued through more contemporary art pieces using modern materials. The dot pantings are still one of the most popular souvenirs for tourists to take home with them.
Ayers Rock A very spiritual place - and I'm really not a spiritual person but I was touched!
Arnhem land near Kakadu and Darwin is probably one of the only places left in Australia where you can see the real culture. Go soon before it becomes over run with tourists.
. is another excellent place for rock art and spiritual places.
Any Australian place where you are at one with nature generally gives you a good aborigine experience. The walks in Tasmania are particularly good for that.
Head to the border of South Australia and the Northern Terriory and the Angatja Bush College and become a Anangu guide's student. You'll get to take part in a hunt, dance, cook and eat bush tucker and camp overnight.
Visit Mungo National Park near Mildura (550km NW of Melbourne or 420km NE of Adelaide) and visit the Walls of China dunes that are over 60,000 years old. Take a tour and discover the home of Mungo Man, one of the oldest bodies ever found.
or the rocks half day dreaming tour taken by Margaret Campbell, an elder.
The Koorie Heritage Trust in Melbourne's centre has a good exhibition on the culture of the southeastern indigenous people.


text:
Another march towards Pharmac funding
Originally published on Te ao
The Medavivors breast cancer survivors group today took another step towards gaining government funding for cancer treatments for suffering New Zealanders. Breast cancer sufferer Wiki Maholland is as determined than ever to live her life on her own terms.
The fight against cancer rages on for these survivors, who say they will continue until the war is won.
Mulholland says, "I just hope and pray that my daughter, my granddaughters or whoever might be coming next. doesn't have to have the same fight that we're having."
It's been six months since their first petitions and on the 20th of March Medavivor members made submissions to the Health Select Committee but still no critical progress is being made.
One Medavivor says, "It's so important that we highlight how broken the system is."
Another says, "The message is that Pharmac's system is broken and there needs to be funding for these drugs that prolong and saves lives."
"Take care of your people," another implores.
Figures released by the Ministry of Health last month show more than 9,500 people died from cancer each year, representing 31 percent of all deaths recorded in New Zealand.
The spectrum of political parties was represented at today's march.
Minister Iain Lees-Galloway spoke on behalf of Prime Minister Jacinda Ardern.
"Pharmac is a construct that we create here at parliament so we have the role of making sure that it works as well as it can."
Co-leader of the National Party Paula Bennett said, "What sort of got me was looking at so many faces and i can see you struggling to have hope in us".
Deputy Prime Minister Winston Peters said, "This is not a time for politicians to start making you promises, other than to say we've heard what you've had to say today."
Leader of the Act Party David Seymour said, "I believe that we have suffered a prejudice against pharmaceuticals for too long."
And finally, co-leader of the Greens, Marama Davidson said, "I can guarantee that I will take your voices, the struggles and challenges that you have faced to the decision-making tables."
The road to recovery has been a daily struggle for Mulholland, but those less fortunate who have passed on are a reminder to her of her purpose.
"I was diagnosed one year ago on May 4th so its been a good time to reflect on things and one thing that I always keep in the front of my mind is that no other family should have to go through this."
Mullholland says she is concerned that the government is still treating this as a clinical decision that needs to be made, and believes it's more about leadership.
Copyright 2018 Myeloma New Zealand, All Right Reserved

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: IIS 10.0 Detailed Error: mimeMap Hello so I'm pretty new to using IIS and Visual Studio but I've managed to launch one website on IIS but when I try to launch this one I get this error across the page:

Error message:

Cannot add duplicate collection entry of type 'mimeMap' with unique key attribute 'fileExtension' set to '.mp4'

There's a section that reads Config Error:so here is my web.config  file:
<?xml version="1.0"?>
<configuration>
<appSettings>
<add key="DetailLogging" value="True"/>
<add key="LoggingConfigFile" value="log4net.config"/>
<add key="DatabaseConnectionString" value="Integrated Security=True; MultipleActiveResultSets=True; Data source=.\SQLEXPRESS; Initial Catalog=WebEvaluation" />

<add key="Email" value="***********************"/>
<add key="SupportEmailID" value="*************************"/>
<add key="ForgotPasswordEmailSubject" value="Butterfly Scheme e-Certification Admin Console - Password Request"/>
<add key="WelcomeMailSubject" value="Butterfly Scheme e-Certification Admin Console"/>
<add key="PasswordChangedMailSubject" value="Butterfly Scheme e-Certification Admin Console - Password Changed"/>
<add key="PasscodeDeleteMailSubject" value="Passcode delete notification - "/>
<add key="Host" value="***********"/>
<add key="PortNo" value="25"/>
<add key="Password" value="***********"/>
<add key="SiteURL" value="***********************************"/>
<add key="RecordsPerPage" value="20" />
<add key="PasscodeCreateMailSubject" value="Butterfly Scheme e-Certification Passcode List created for : "/>
<add key ="XlsConnectionString" value="Provider=Microsoft.Jet.OLEDB.4.0;Data Source={0}; Extended Properties='Excel 8.0;IMEX=1'"/>
<add key ="XlsxConnectionString" value="Provider=Microsoft.ACE.OLEDB.12.0;Data Source={0}; Extended Properties='Excel 8.0;'"/>
</appSettings>

<system.web>
<compilation debug="true" targetFramework="4.0">
  <assemblies>
    <add assembly="System.Design, Version=4.0.0.0, Culture=neutral, PublicKeyToken=******************"/>
    <add assembly="System.Web.Extensions.Design, Version=4.0.0.0, Culture=neutral, PublicKeyToken=******************"/>
    <add assembly="System.Windows.Forms, Version=4.0.0.0, Culture=neutral, PublicKeyToken=B77A5C561934E089"/>
  </assemblies>
</compilation>
<httpRuntime requestValidationMode="2.0" maxRequestLength="2097151"
executionTimeout="900"/>
<sessionState mode="InProc" timeout="20"/>
</system.web>

<system.webServer>
<modules runAllManagedModulesForAllRequests="true"/>
<staticContent>
  <mimeMap fileExtension=".mp4" mimeType="video/mp4"/>
  <mimeMap fileExtension=".m4v" mimeType="video/m4v"/>
  <mimeMap fileExtension=".3gp" mimeType="video/3gpp"/>
</staticContent>
<security>
  <requestFiltering>
    <requestLimits maxAllowedContentLength="2147482624"/>
  </requestFiltering>
</security>
</system.webServer>
</configuration>

A: You could add something like this:
<remove fileExtension=".mp4" />

Or, since the MP4 mime type seems to be already present in the roots configuration file, simply omit the whole line:
<mimeMap fileExtension=".mp4" mimeType="video/mp4"/>

If you really want to be sure that the extensions you seem to require are present, this could be a replacement for the staticContent tag:
<staticContent>
    <remove fileExtension=".mp4" />
    <remove fileExtension=".m4v" />
    <remove fileExtension=".3gp" />

    <mimeMap fileExtension=".mp4" mimeType="video/mp4"/>
    <mimeMap fileExtension=".m4v" mimeType="video/m4v"/>
    <mimeMap fileExtension=".3gp" mimeType="video/3gpp"/>
</staticContent>

A: Could not load type "PresentationLayer.Global"
Check if you namespace is PresentationLayer or is changed? If changed update it in the markup, by right clicking on Global.asax and select "View Markup"

redpajama_set_name: RedPajamaStackExchange


Linux mint is trying to forge away from Ubuntu, Kubuntu derivatives and that is a very encouraging change since they are going back to basics.
Go back to Debian base and forge ahead.
Reason being the change of canonicals to Unity.
I am one who is in favour of mark Shuttleworth's smart move.
Yes it is a smart move by him.
He is doing a Bill Gate to Linux Community.
Linux missed the opportunity for netbooks and I do not want to see it misses on tabloid too.
Like iPads, tabloid is the future.
We must not let only Apple to dominate the market.
Google's Android has shown the way and Ubunbtu should not miss this opportunity come what it may.
I am highlighting Linux Mint here since it overtook Ubuntu head and a nose recently in downloads at DistroWatch and Ubuntu in the last week or so putting its nose ahead again.
Linux Mint did not miss time in promoting both Ubuntu 10 and Ubuntu 11 base.
Not only that it did not forget the Debian and out came Debian Mint in Last December.
Linux Mint was thinking ahead and getting ready for all the consequences resulting from Unity experience and not forgetting the community they were with.
Like PCLinux Linux Mint gave variety of options and Long Term (LTS) support and rolling editions and also brand new version based on Debian for the newcomers and the newbies.
This is what was lacking with Ubuntu.
They did not have two versions but with too much enthusiasm promoted Unity only.
They can reverse this by supporting their community who were with them when Microsoft was dominating the field.
It is not too late, let the user decides the trends of the future what canonicals and Mint and Debian should do is to be ready for all the eventualities including brickbats were call in our country.
God Luck to everybody in Linux and especially the developers and without you we do not have a customer base,too.
In any case innovation is the future for IT both hardware and software.
DOSand Atari games of the yesteryear.
The answer is not Microsoft but AbiWord.
What determines the Flight Paths of Birds?
Why I wont buy a Tabloid soon?


Put your passion into practice with our introductory 2 day Ableton Live course for aspiring music producers and composers. DESCRIPTION Through hands-on exercises you�ll discover Live�s powerful features to create your own track from scratch.... 7/08/2013�� i started learning ableton live at the beginning of my pc composing hobby in about 2005/2006. first, i only used arrange view. gradually, i tried to wrap my head around the session view. now, after 7 years, i like the session view much more than at the outset.
He then moves into creating basslines via analog synthesis and creating lead synth sounds with Ableton Live's built-in Operator synth. He also goes into how to create and use samples and MIDI effects, and use Push 2 for production and mixing. He pulls it all together in the final few chapters, which demonstrate ways to arrange tracks, use creative effects, mix tracks together, and use... Put your passion into practice with our introductory 2 day Ableton Live course for aspiring music producers and composers. DESCRIPTION Through hands-on exercises you�ll discover Live�s powerful features to create your own track from scratch.
Simply put, the Ableton Live 9 Suite (Boxed) is the best and most complete version of Live ever conceived. Whether you've been using Live for years or you're looking for a new way to create and perform music, Live 9 is the way to go. Its flexible loop/riff-based Session view lets you write music in pieces and freely arrange your songs on the fly. But Live 9 Suite is far more than a DAW; it's a... 3/09/2008�� Quoting from the Ableton Live Power book; "There is one very important distinction between Session View and Arrangement View. Once you record your music from Session View into Arrangement View , you will hear your new arrangement (playing from Arrangment View) until you override it by executring a control in Session View or by activly moving a previously automated control."
Ableton Live makes it possible to utilize plugins stored in different folders on the computer. To do this, create a Mac OS or Windows alias of the folder where additional VST Plug-ins are stored, and then place the alias in the VST Plug-In Custom folder (or in the VST Plug-In System folder on Mac OS X) selected in Live's File/ Folder Preferences.... Is there anything else for creative composing along the lines of Ableton Live? The session views make a lot of sense. It's a nice program. And ultimately I believe professional music can be make... The session views make a lot of sense.
This means you can continue to trigger Clips live, or edit or record arrangements in the Arrange view. Normally, when you freeze a track that has a hardware insert or controls an external instrument, Live does a real?time record of all Clips, which may take time.
BUT, if, after, you go back to Session View, and start launching clips from the same Audio Track, Live thinks you are now improvising on what was previously recorded to the arrangement. Because Ableton was built for Live performance, Session View has a higher priority than Arrangement View.
Well, suppose you made a song and drew in some fancy automation in Arrange, but you wanted to move the song back to Session to work on in in a non-linear way, or play it live. You need everything to be in Session View to launch Scenes.


The car key replacement we use in Ballydehob are experts in lock repairs and replacements for both domestic and commercial clients. Our focus on customer service and value for money makes us the number one choice for major companies and home owners alike!
Do they offer car key replacement in Ballydehob?
Determine the costs for any car key replacement Ballydehob services before any works being completed. Along these lines, you are not got out by substantial bills you have nothing to do with.
Check whether a locksmith offers free gauges as a feature of their car key replacement Ballydehob services. Once more, this keeps any false impressions over installment before work is started.
Whether you are locked out of your car, home, or need a new set of locks set up, you'll want to make certain to employ a trustworthy locksmith. BBB suggests finding a trustworthy locksmith prior to one is required.
Locksmithing usually needs some type of apprenticeship, though official education can vary anywhere from a certificate to a diploma from an engineering college. Locksmiths can have a physical shop or be mobile. Lots of locksmiths deal with not simply locks themselves, but other existing door hardware, including door hinges, frame repair work, or making keys. Associated Locksmiths of America (aloa.org) is a global company of locksmiths and other physical security specialists. There is an application process, background check, and application and charges costs which should be present in order to join.
Request for Recommendations. Contact pals, member of the family, and neighbors for suggestions of respectable locksmiths in your location. Be sure to validate the physical address of any locksmith you discover and make sure the address is really regional. See bbb.org/indy for a listing of certified locksmiths, to check out BBB Business Reviews and Customer Reviews from previous consumers. Ensure business does not have any unanswered/unresolved grievances.
Call business. Be wary if business responds to the phone with a generic expression like "locksmith services". Ask exactly what their legal company name is and if they are unable to offer it to you, look somewhere else for a locksmith. Search for a company that answers the phone with their specific business name.
Request an Estimate. Prior to having the locksmith come to your home or car, make sure to get a quote that includes the expense of all labor and the replacement parts for the lock. Trusted locksmiths will be able to offer you an estimate over the phone.
Ask about extra costs including: if you will be charged extra for services in the middle of the night or weekends or if there is a charge by the millage they need to take a trip. If when the locksmith arrives they are charging a greater rate than on the phone, don't enable them to start working. Beware to never ever sign a blank document to license work.
Inspect Credentials. Make sure that the locksmith you employ is insured so you will be covered in case the repair results in damages. Upon arrival, ask the locksmith to supply identification and/or a company card. It's also crucial to check if business name and logo design on their service cards match the name and logo design on the invoice and vehicle. A reputable locksmith will likewise request to see your identification to make sure it's actually your home or business they are doing work on.
Conserve Their Information. After the locksmith has completed the job, get a made a list of billing that includes: parts, labor, mileage, and other costs and save this file for future referral. If you believe you have discovered a respectable locksmith, you ought to keep business' name and information kept in your wallet or mobile phone in case their services are needed in the future.
Whether it's for a planned home enhancement, or an emergency situation lock-out circumstance, utilizing a reliable locksmith is essential. Do your homework before working with a locksmith for non-emergency situations and have a locksmith's contact info that you have actually already investigated useful for those emergency circumstances.
Dyno Lock car key replacement Ballydehob is your emergency locksmith security company. We are an emergency 24 hour locksmith give us a Call Its Free: 1800 800 800.


text:
Q: Help parse "false as could be"
As a musical experience, Eddie Howlloway Live at the Silver Lounge was
a jolt. Two songs, originals, were vehicles for Eddie to describe,
simply and sincerely, his enormous lovemaking abilities. These didn't
interest me except as examples of fine lyrics and vocal delivery.
Three other originals, however, provoked me in other ways. These not
only referred to me by name, but described my lifestyle ("dull as a
mole in his dark hole"), career ("he strikes a pose, this writer of
indifferent prose"), and way with women ("slick and insincere, don't
let him call you dear") in outrageous terms. Here then was another
artist who, like Kelly, was able and willing to insert personal notes
about me and girlfriend into his music, to make a point. But
while Kelly's personal references were true, as I myself had verified,
Eddie's were false as could be. Both artists, however, were true
song stylists who succeeded in making genuine music. I couldn't
overlook that, for all my personal involvement in their sounds.
The dangerous singers By Michael Fowler ( it's from one of my old magazines on English-learning, but sorry I couldn't find it on the Internet.)

Why false as could be, not as false as they could be? I've never come across such structure before. Is it an ellipsis?
Please help clarify it.

A: False as could be does indeed omit the initial as in an as ... as construction. That is very common in informal registers, and may be acceptable in formal registers. As could be is not an ellipsis of as X could be but an idiomatic expression employing be in the intransitive noncopular sense of "exist, occur". It thus means approximately "as possible".  You may also encounter as can be and, with a more tentative or dubious sense, as may be or as might be.

She petted me and seemed to try hard to make everything as pleasant as could be. —Henry Adams, Letters
Look here, folks, don't think I'm rough / 'Cause I'm a good woman and I knows my stuff / That's why I'm sinful as can be. –Perry Bradford, "Sinful Blues"
The Commission shall keep itself informed as fully as may be of the circumstances ... —State of Texas Constitution
"That's as may be," said Kantwise. "I say nothing on that subject at the present moment, either one way or the other." —Trollope, Orley Farm
My father's dramatic instinct was as strong as might be. And his power of mimicry was positively fantastic. —May Morris, Introductions to the Collected Works of William Morris

You will also encounter an intensive version: as ADJ as ADJ can/could/may/might be, where be has the same noncopular sense:

The feeling there was as strong as strong could be that Parnell's leadership is, for the time at least, intolerable. —John Morley to Gladstone.

A: I couldn't find any solid sources, but "as _ as can be" is an idiom, which basically means "as _ as possible". Here's thesaurus.com with "easy as can be". "as could be" is just a variation on that. If you Google it, there's lots of usage.


Tacoma Housing Authority (THA) has other programs besides the Housing Choice Voucher Program that help pay rent on a dwelling. THA usually manages these programs in partnership with other community agencies.
THA has agreed to attach some of its vouchers to units in specific apartment buildings owned by for-profit or non-profit private owners. Doing this provides several advantages to the owner. It helps to get financing to build or renovate the housing. It makes some of the units in the building affordable for a long time, generally 15 years. If the building has market rate units, these arrangements provide a good mix of incomes among the families in the building. The assisted families pay the same rent that they would in the regular voucher program.
The City of Tacoma provides THA with funds to manage a separate rental assistance program. It is a small one, serving about 20 families. THA chooses its families in partnership with other social service agencies and school districts. Generally, this assistance lasts two years. After that time, THA tries to transfer the family to the regular voucher program.
A single room occupancy (more commonly SRO, sometimes called single resident occupancy) is a multiple tenant building that houses one or two people in individual rooms. Sometimes tenants in several units share a bathroom down the hall.


text:
Devices FDA
News Release - May 2, 2008
Stryker's Biotech Division Receives FDA Warning Letter
KALAMAZOO, Mich., May 2 (HSMN NewsFeed) -- Stryker Corporation (NYSE: SYK ) announced today that its Biotech division has received a warning letter from the U. S. Food and Drug Administration (FDA) related to quality systems and compliance issues at its Hopkinton, Massachusetts location.
The warning letter concerns observations made during an inspection that was initiated in September 2007. The letter primarily cites issues relating to Stryker Biotech's handling of a past clinical study, its quality system including medical device reporting procedures, and the integrity of hospital Institutional Review Board (IRB) documentation used to approve implantation of Humanitarian Use Devices.
Several corrective actions and changes to processes put in place by Stryker Biotech were noted in the letter and future improvements are forthcoming as the division continues to work with FDA. No products have been recalled as a result of this warning letter. In addition, there were no observations related to any ongoing clinical trials or clinical trial IRBs.
"We take this matter very seriously, will continue to cooperate fully with FDA, and have initiated significant measures to address FDA's concerns," said Stephen P. MacMillan, President and Chief Executive Officer of Stryker Corporation.
In addition to specific corrective actions implemented at the Biotech division, Stryker recently launched a company-wide Quality Action Plan aimed at strengthening corporate-level oversight and at institutionalizing a more consistent implementation of best practices for meeting FDA requirements.
As part of its Quality Action Plan Stryker has:
-- Strengthened roles and responsibilities to increase accountability for quality
-- Established new company-wide standard operating procedures for quality processes that will be implemented consistently at each division
-- Reorganized quality functions at the plant, division and corporate levels and increased third-party monitoring at all levels
-- Tied a significant portion of senior management's compensation to meeting quality improvement measures
"We are committed to strengthening our quality systems to fully meet all FDA requirements. While we have made progress in fulfilling this commitment, we still have more work to do" MacMillan added.
This press release contains information that includes or is based on forward-looking statements within the meaning of the federal securities law that are subject to various risks and uncertainties that could cause the Company's actual results to differ materially from those expressed or implied in such statements. Such factors include, but are not limited to: pricing pressures generally, including cost-containment measures that could adversely affect the price of or demand for the Company's products; regulatory actions; unanticipated issues arising in connection with clinical studies and otherwise that affect U.S. Food and Drug Administration approval of new products; changes in reimbursement levels from third-party payors; a significant increase in product liability claims; changes in economic conditions that adversely affect the level of demand for the Company's products; changes in foreign exchange markets; changes in financial markets; and changes in the competitive environment. Additional information concerning these and other factors is contained in the Company's filings with the U.S. Securities and Exchange Commission, including the Company's Annual Report on Form 10-K and Quarterly Reports on Form 10-Q.
Stryker Corporation is one of the world's leading medical technology companies with the most broadly based range of products in orthopaedics and a significant presence in other medical specialties. Stryker works with respected medical professionals to help people lead more active and more satisfying lives. The Company's products include implants used in joint replacement, trauma, craniomaxillofacial and spinal surgeries; biologics; surgical, neurologic, ear, nose & throat and interventional pain equipment; and endoscopic, surgical navigation, communications and digital imaging systems; as well as patient handling and emergency medical equipment. For more information about Stryker, please visit the company web site at www.stryker.com .
Source: Stryker
Search: Stryker
Stryker launches T7(TM) personal protection system
CMS grants transitional pass-through (TPT) payment for Stryker's SpineJack(R) System
Breg Appoints Former Stryker President to Executive Chairman


Relocating when you perform from dwelling is slightly more difficult - the household office is even more hard to move - you are moving your operate location As well as your residence.
What are you able to do to make the transfer less difficult? Probably obtain the solutions of a man and van Bedford removals services?
Transporting your home workplace, like every other move, is about preparing the non essentials - in the event you are not working with your printer significantly, go ahead and box it, and a few document up - keep it handy so that it is possible to pull it out and then use it should you want it. Packing Boxes If you do use it, but not your USB, or other components of the pc frequently, think about boxing them away as quickly as you'll be able to.
It is possible to additionally cease this likelihood to clear out or make a decision whether anything is requiring replacement. Found cartridges of ink that you wish to recycle? Take them back or get them refilled as quickly as you may - then store them away - its one particular much less job to deal with - and it is going to save you income for those who use them to be refilled (if your cartridge supports that).
You'll also have to think about shipping concerns - for those who collect things on a regular basis, you will have to make arrangements for them - if you've got stock that is on a regular basis sent to you, what will come about within the 'grey' region in between your old house and new house, if there's 1? godwins removals can provide a terrific removal support.
Moving your house workplace is usually difficult, and exhausting, but effectively worth it inside the lengthy run - that corner you claimed within a rush if you began functioning from household could turn out to be a effectively planned nook in your new residence, using a tiny imagination.


text:
Fears grow in Skegness as people head to the coast in scorching weather
It's been the hottest day of the year so far - and that's led to a rise in visitors
Sam Atkin
Skegness beach was busy, despite East Lindsey District Council urging people to stay away (Image: Sam Atkin)
Keep up to date with every Skeggy story by signing up for our free email updates
People in Skegness are becoming more anxious about the number of people flocking to the coast to get some sun during lockdown.
As fish and chip shops, ice cream stalls and car parks reopen, Skegness has seen a big increase in the amount of people visiting the town, despite lockdown having only been lifted slightly by the government.
And today, Wednesday, May 20, Skegness beach and the surrounding areas were packed with families desperate to escape the confines of the home to bask in the sun on the hottest day of the year so far.
But some people in the town are worried about this influx, as people took the opportunity to get ice cream and chips, while playing ball games and sunbathing on the beach. Some even brought picnics.
People spent the day at the beach with their families (Image: Sam Atkin)
This is despite East Lindsey District Council's warning for people to stay away from the coast.
Graham Rhodes and Doreen Bailey are both from Skegness. While they were sat out in the sunshine, the elderly couple said they were worried about how busy the seafront was.
"It's the first time we've been up here since the lockdown and I can't believe it." Doreen said.
"We've just been along the seafront and there are no seats free.
"There are a lot of people here just mixing together.
"It seems like people just don't care," she added.
Long queues for toilets on the coast as people ignore stay-away message
Lincolnshire council leader threatens BBC interviewer with "dead air" over public toilet questions ahead of bank holiday weekend
Graham explained that he's surprised by how many businesses on the seafront have reopened.
"I'm surprised all of the kiosks are open. All the people in Skegness are telling them they shouldn't be.
"This government has made a pig's ear of this," Graham said, adding that he thinks the town will continue to get busier until there's a second wave of the virus.
One woman, who is from Hogsthorpe near Skegness, said it also worried her how busy the seafront was.
"I haven't seen my friend for ages so we thought we'd both come now we can see each other in public," she explained.
"But I hadn't quite realised how busy it would be. There are that many people here, it would be safer to sit in the garden.
Kiosks selling ice cream and refreshments have reopened (Image: Sam Atkin)
"I'm feeling a bit exposed," she added.
A man working in the town centre said he was frustrated with the influx of tourists, adding: "These people are the reason we're going to get a second wave."
But while locals expressed their fears, others who had visited the town for the day from elsewhere were less reluctant to talk about why they had come to Skegness.
One couple, who asked not to be identified, had travelled from Nottingham to spend the day by the sea.
"We've come on a rare day trip," they said.
Many of the town's fish and chip shops have reopened in the last two weeks (Image: Sam Atkin)
"I think people have got to get out, it's as simple as that," they added.
Meanwhile, car parks have reopened – some of them free of charge – and so have fish and chip shops, ice cream and refreshments stalls and even the town's KFC – which had a large queue at its drive through.
The toilets near the seafront are still mostly closed – but there was a large queue for the disabled toilet, which is open.
One local trader, who was getting his small food business ready to reopen near the beach, said Skegness needed to start getting back to normal for the sake of the town – and that the tourism boom was a good thing.
"We've got to progress. Skegness is a one-trick pony – we only have tourism which comes with a summer boom. If you don't make your money then, you'll go bust," he said.
"What better big open spaces are there than the beaches? We've got massive beaches. They should let people come to the coast, maintain social distancing and open takeaway food outlets only.
It was tricky to find a parking space anywhere near the beach (Image: Sam Atkin)
"I think you have to test the water. You have to open toilets and car parks.
"If it backfires a bit, we'll go back into lockdown," the businessman added.
He said he was worried about the long-term impact on Skegness as a town if lockdown goes on until the end of summer.
"At the moment, we're being hampered as a resort," he said.
"The message is currently 'stay away from our coast' but what that feels like is 'we're throwing you and your businesses under the bus.
Met Office warns thunderstorms could bring UK heatwave to an end with several hours of rain, hail and lightning all possible
All the shops that can now open after Government eases lockdown rules - and the ones that can't
"We've got to move on and we've got to get open.
"But not if it gets rampant," he added.
And some businesses that have reopened say they are feeling a backlash from people who think they should have stayed shut.
One seafront business said they didn't want to make a comment. "We're getting so much rubbish from people on Facebook that I'm not willing to say anything," one member of staff said.
David Wilkinson and Liz Beckford said they chose to reopen The Blue Fin, a fish and chip shop, at the start of last week.
While they explained that business had been slow so far, they said they felt they had no choice but to reopen.
"We've got to get back to normal eventually," David said.
He added that certain things needed to be changed before the town can start to benefit from tourism properly again: "They need to open up the toilets," he said.
Liz said she'd noticed the town getting busier: "People are starting to come out a little bit more – more than they should do maybe."
Rescue plan for Lincs town with 9th worst vaccination rates in England
BostonFunding has been announced to improve its vaccine uptake
Boris JohnsonLive updates as Boris Johnson could scrap Plan B Covid restrictions amid reports of vote of no confidenceA number of letters have already been submitted
Tesco shopper 'absolutely disgusted' by lack of face masks in city centre store
UK & World NewsSue Davies decided to challenge her fellow customers
Kingfisher Caravan Park changes could lead loss in income for council
East Lindsey District CouncilA row about the site on the Lincolnshire coast has resulted in court action
Dog owners warned driving in the car with their pooch could lead to a £5,000 fine
BBCThe Highway Code spells out the rules


text:
require 'spec_helper'

describe RubyCAS::Server::Core::Util do
  before(:all) do
    Util = RubyCAS::Server::Core::Util
  end

  describe '.build_ticketed_url(service, ticket)' do
    let(:ticket) { 'ST-12345EDCBA' }
    let(:service) { 'http://www.google.com' }

    it 'must add the ticket to our query string when none was present' do
      ticketed = Util.build_ticketed_url(service, ticket)
      expect(ticketed).to eq("#{service}?ticket=#{ticket}")
    end

    it 'must add the ticket to the query string when one is already present' do
      ticketed = Util.build_ticketed_url("#{service}?param=value", ticket)
      expect(ticketed).to eq("#{service}?param=value&ticket=#{ticket}")
    end

    it 'must return an empty string when no service url is present' do
      expect(Util.build_ticketed_url('', ticket)).to eq('')
    end

    it 'must return an empty string when service url is nil' do
      expect(Util.build_ticketed_url(nil, ticket)).to eq('')
    end
  end

  describe '.clean_service_url' do
    it 'must return an empty string when an empty value is passed' do
      expect(Util.clean_service_url('')).to eq('')
    end

    it 'must return an empty string when an nil value is passed' do
      expect(Util.clean_service_url(nil)).to eq('')
    end

    it 'must strip off a trailing ?' do
      cleaned = Util.clean_service_url('http://www.google.com?')
      expect(cleaned).to eq('http://www.google.com')
    end

    it 'must strip off a trailing &' do
      cleaned = Util.clean_service_url('http://www.google.com?param=value&')
      expect(cleaned).to eq('http://www.google.com?param=value')
    end

    it 'must remove empty params' do
      cleaned = Util.clean_service_url('http://www.google.com?&')
      expect(cleaned).to eq('http://www.google.com')
    end

    %w{service ticket gateway renew}.each do |param|
      it "must remove any '#{param}' params" do
        url = "http://www.google.com?#{param}=value"
        cleaned = Util.clean_service_url(url)
        expect(cleaned).to eq('http://www.google.com')
      end
    end

    it 'must leave other params intact after removing our sensitive params' do
      url = "http://www.google.com?something=booyah&gateway=true&param=value"
      cleaned = Util.clean_service_url(url)
      expect(cleaned).to eq('http://www.google.com?something=booyah&param=value')
    end
  end

  describe '.random(length = 29' do
    context 'when max length is not passed in' do
      it 'should return a random string of length 29' do
        Util.random_string.length.should == 29
      end
    end

    context 'when max length is passed in' do
      it 'should return a random string of the desired length' do
        Util.random_string(30).length.should == 30
        (Util.random_string(30) =~ /(\w|-){29}/).should eq(0)
      end
    end

    it 'should return a random string' do
      random_string = Util.random_string
      another_random_string = Util.random_string
      random_string.should_not == another_random_string
    end
  end
end

redpajama_set_name: RedPajamaGithub


text:
£29.50The price you'll pay. No surprises later.
With a vocal that's instantly recognisable and a career that's been deeply influential, Joanna Newsom's art is unparalleled. With a style that flirts between classic singer-songwriter, traditional folk, and outsider avant garde, and mastering the harp and piano with tender grace her songs grow through captivating narratives and emotions.
Soaring into the hearts of music fans with 2006's Ys, Newsom's live shows became must attends as she forged new ground for folk music. And despite eschewing any particular scene, she's become a figurehead for anyone walking their own path.
Announcing new album Divers due this October, Newsom plays this special date at Albert Hall. Get ready to be stunned by an evening of arresting beauty and personal tales told with an unprecedented talent.
Presented by DHP Family.
This is a 14+ event. Under 18's to be accompanied by an adult.


It has become nearly impossible to change Evan's diaper these days…not to mention dressing him! As soon as we put him on the changing table, he flips and tries to crawl to the wipes tub, grabbing everything within reach. Usually, I have to change his diaper on the floor while he is distracted by a toy or the dog. He also tries to roll and crawl during breast feedings. He will often roll away from me, and then lean his head towards me to try and feed in the crawling position. Our little man is so active now, we can't believe it!
This entry was posted on Saturday, April 10th, 2010 at 6:05 pm	and is filed under Parenting. You can follow any responses to this entry through the RSS 2.0 feed. Both comments and pings are currently closed.
Both videos made me laugh! Evan is so interested in everything. It is too boring to be still and wait for a diaper change! Having something to explore provides a necessary distraction. Did he figure out how to open the wipe's container? When I visited, I got such a kick out of his interest in opening and shutting anything and everything. He sure does want to figure out how things operate!
what a wiggle worm! He looks like he can get up on his knees and crawl right off the table. He is obviously a little man with places to go and the world to explore. Diaper changing is just not as exciting as it used to be. May it is time for Kyle to help Daddy do the diaper change, but then Erik would need 3 hands.
Thanks for sharing these great moments in Evan's development. We are really looking forward to our visit in May.
PS Lola is very impressed at how Tink is handling the little boy in her life.


We custom make your own unique window curtains / door curtains to suit your personal lifestyle, design styles & decor.
Anything is possible. There are thousands of fabrics, plenty of designs and styles to choose from.
Add elegance and luxury to your home or office.
Whoever said interior designing and home decoration is an easy feat, lied! As if choosing the perfect style of windows for your home wasn't difficult enough, picking the right window curtains is an issue on a whole new level. Where do we even begin? If you're thinking fabric swatches and colour options, we'd like to ask you to please stop right there.
To ward off the possible headache that window curtains could be, we've greatly simplified the window curtain choosing process into five (5) easy steps. We find that methodology works best when decorating. So just pick up a paper and a pen, and follow along.
The first and foremost step to perfect window curtain shopping, is to define the purpose of said window curtains.
Are you looking for window curtains for a specific part of the house (living room, bedroom, children's room, bathroom, kitchen, home office)?
Enjoy window treatments that add elegance & luxury to your home!
Thinking of making your office stylish with light-filtering window curtains?
Quality yet attractively priced window curtains for office that offer privacy & match your office furniture!
Are you thinking of adding comfort and warmth to your outdoor patio / living spaces with the outdoor curtains?
Bring your outdoor style to life with our weather resistant outdoor curtains!
Are you looking for customising your stage curtain, event drape, or backdrop? There are different types of stage curtains – traveler, tableau, venetian, venetian contour, … It can be confusing.
Let us help you with designing and custom made to your specification and budget!
Once you've finalised the purpose of the window curtains you'd like to buy, you can move onto the most important step of deciding the features and functionality of the window curtains. We realise style considerations are often on top of the list, but often functionality takes precedence.
Day and night curtains are meant for the different times of day. The day curtains are light and translucent; meant to be illuminating, while the night curtains are the opposite, designed to obscure the light.
Blackout curtains are window coverings that are made specifically to block out the unwanted light from any and all external sources.
Soundproof curtains are heavily lined and coated to dampen noises and block off any and all unwanted sounds.
Eliminating the need for cords, tie-backs, and cables, motorised curtains are remote controlled and operable at the touch of a button.
Window curtains are an indispensable part of your interior overhaul, and are considered a particular favourite of interior designers for they bring a beautiful mix of functionality and beautification. While picking the right one does seem like a whole lot of work, the fact is, it's the attention to detail that reflects an owner's love for their home.
For us, the ultimate reflection of a homeowner's exactitude and care is the curtain headings; even more so than the material of the curtains themselves. Before you begin to wonder what a curtain heading is, it's the pleating or gathering of the fabric at the very top of the curtain that is hung onto its rod.
The style of the curtain heading speaks volumes about an individual's personal taste and thoroughness for each particular design uses a different material and creates a different outlook.
Now that we've told you so much about the curtain headings and how important they are, it's only right that we help make your decision of choosing the right one a tad bit easier. Here we've put together a list of some of our most popular designs for you to go through. We're confident you'll find the one you love the most.
Eyelet curtain headings, specific to curtain poles have even shaped eyelets open to create loose folds at regular intervals of the curtain.
Goblet pleat curtain heading is designed in a way that the stitched pleat creates a row of goblet shapes at the very top of the curtain itself.
Pencil pleat curtain headings create an even gathering of the curtain due to the slim folds of the pleats gathered and stitched together.
Pinch pleat curtain heading consists of single, double or triple pleats sewn together to create a formal look.
Reverse pleat curtain heading is created by folding two equal lengths of the material towards each other so that they meet right in the middle of the pleat.
Rod pocket curtain headings offer a far more casual look where a pocket is sewn right across the very top of the curtain allowing the curtain rod to be inserted straight in.
Other options of window curtain headings include swags, valances, pelmets and tails.
Once you've decided on the curtain headings, you can move onto the fabric swatches for colours, textures.
Get inspiration with a range of good quality fabrics, with a wide choice of patterns and designs.
Decorate your room subtly with our collection of sheer curtains. Let the daylight pass through yet provide privacy.
A range of medium weight and lightweight linings, use it for both aesthetic and practical purposes.
Give your space a fresh and alluring look with our vintage lace curtains.
A modern alternative to window curtains. Both decorative and practical, protects against unwanted looks.
Add artistry and a glittering touch to your space, with our collection of iridescent beaded curtains.
Opening and closing your window curtains daily, whilst keeping them looks perfect and elegance can depend on the type of curtain accessories you choose.
Check out the suitable curtain accessories like curtain tiebacks, tassels, holdbacks, trims, poles, tracks, rods, finials or rings and lots more. Add the final flourish to your window curtains.


The lines of the new Mondeo are rather nice. It disguises its length with a curvaceous front end, and features some bold swoosh lines down the side. The Vignale trim adds flashes of chrome all around, from the grille and fog light surrounds at the front, to some side bump strips and window surrounds. Chrome dual exhausts complete the exterior package. Finished in Magnetic my test car looked superb, and there are three exclusive colours available- Ruby Red, Milano Grigio and White Platinum- should you wish to stand out from a crowd. I'm not completely sold on the polished alloy wheels, but these are an optional extra so if they don't tickle your fancy you can leave the box unticked.
Inside the Vignale is noticeably more premium than other Mondeo's. The first thing that will grab your attention is the trim. The seats are finished in a premium leather, with a contrast border, perforation and hexagonal pattern. Look a little closer and you will notice that the dashboard is also leather, which is a really nice touch. The dials are a pair of TFT displays, which are crisp and clear for the driver. Nestled into the centre of the dashboard is an 8-inch touchscreen which features the brilliant SYNC 2 system, and the dashboard features plenty of silver trim to contrast the black leather. It feels airy and light, and is a welcoming space.
There are numerous drivetrains available on the Vignale, but my test car came with the one that is the most interesting. It's a 2.0-litre diesel engine producing 180PS and 400Nm of torque. Now I know that may not seem that interesting, but bear with me. You see this Vignale was AWD and featured a Powershift automatic gearbox. 0-62mph is dealt with in 8.6 seconds and the top speed is 138mph. That makes the Vignale relatively brisk, but it's not about that. The Powershift transmission is remarkable; gear changes are instant but don't break your neck. Motorway cruising is a delight, with the torque available should you need some overtaking grunt.
The AWD system is a revelation on the Vignale, and frankly I'm surprised it's taken Ford this long to offer it on a Mondeo considering the success of Audi's Quattro system for many years. Despite only having 180PS the Vignale can use all of this, all the time. It just grips and grips. The steering is direct and nicely weighted, whilst the ride is a nice balance of comfort and composure. This isn't a car to be hooning down a country lane, but you could. Even in the wet. The down side to this is it highlights that there should be a Mondeo ST. This chassis is crying out for an engine to match… come on Ford!
The diesel engine comes with start stop technology in a bid to improve fuel consumption and reduce emissions. The Powershift gearbox is also optimised to improve efficiency, and as a result the Vignale returns 53.3mpg on a combined cycle. CO2 emissions are 138g/km putting the Vignale in VED band E. Road tax is £130 in the first and subsequent years, which is not too bad for a large, AWD executive saloon. There is also a hybrid version available with CO2 emissions of 99g/km if you want something a little more economical, but I think the diesel is a happy medium.
There are certain qualities you would expect from a Mondeo; big boot, specious cabin and easy to live with. The Vignale ticks all those boxes and then some. The cabin can seat 5 adults, and tall people are fine in the back. The boot is large, but has a restricted opening due to being a saloon. There is an estate version available for those with dogs or more significant haulage requirements. To live with the Vignale is fantastic. From the wonderful SYNC 2 system, to the adaptive lighting, keyless entry and go, rear-view camera and lane keeping aid; the Vignale has it all. There is even a system called Active Noise Control, which emits specific sound waves into the cabin to drown out noises such as engine, transmission or wind. This is a car that doubles as a pair of noise cancelling headphones, allowing you to enjoy the sound from the Sony stereo. I like that.
So that concludes my time with the Mondeo Vignale. On paper I wasn't sure if it would have a point; I wasn't entirely convinced a luxurious Mondeo would make much sense. However after spending some time with it I get it. It looks good, drives great, and even as tested costs £33,645. That's rather good value, and for that you're getting the staple car that has become synonymous of Ford. If you are thinking about buying an executive saloon, then I might just urge you to think twice before signing up for a BMW 320d. Head over to the Ford website or visit a local dealer. Take a look at the Vignale, and do as the adverts say: unlearn. Mondeo Man has put his tuxedo on.


Enjoy a heady mix of culture and romance! Begin your travel discovering North India's cultural heritage, including the Taj Mahal. Then, indulge in the luxury of the Maldives with its white sandy beaches. Ideal for lovers of any age, this magnificent vacation boasts unadulterated pleasure!
Experience historic landmarks amidst the cosmopolitan chic. Venture to 16th century blackened Dodda Ganeshana Gudi (Bull Temple) dedicated to the sacred bull Nandi. Venture to the imposing Vidhana Soudha, a Neo-Dravidian building that houses the seat of state legislature. Tour Bangalore Palace, still owned and inhabited by the erstwhile royal family of Mysore. Visit Bangalore's British colonial gardens – Lal Bagh, which includes a Victorian glasshouse replica of London's original Crystal Palace, and Cubbon Park. Glimpse Electronic City, where the city's booming IT industry congregates. Head to the stunning ISKCON Temple (International Society for Krishna Consciousness) to observer worshippers of the Hare Krishna movement. Explore Tipu Sultan's Fort and Palace, and the Government Museum, one of the oldest museums in India and home to many artifacts from the Neolithic period.
Male finds mention in almost every traveler's wish list for being the gateway to the incredible Maldives' islands.
If you are planning a trip to India or the Maldives you need to talk to Enchanting Travels. Anita and Sanchi provided the attention to detail and expertise to help make our experience amazing. We are pretty seasoned travellers and will ONLY use Enchanting Travels going forward.


said his version of the Peter Jackson movies was "a lot tighter."
andreasj1981 I deleted your post as it has nothing to do with the thread topic. I would encourage you to post in a thread more relevant if there is one available, or just send a PM.


text:
Karen L. Davidson
Writer, reader, talker, listener
Video and Film Projects
19/06/2018	• 0
Dr. Ritsuko Komaki: The Cancer Fight, from Hiroshima to Houston
THE CANCER FIGHT, FROM HIROSHIMA TO HOUSTON
Dr. Ritsuko Komaki was living with her family near Osaka when the atomic bomb exploded on her native Hiroshima in 1945. But the family returned to the devastated city when she was four, and Komaki grew up a witness to the long-term effects, which likely contributed heavily to the deaths of about half her relatives, including her father. Like many Japanese, she developed both a fascination with and fear of radiation. When her close friend Sadako Sasaki died at age 11 of radiation-related leukemia, Komaki vowed to become a cancer doctor.
Today, Dr. Komaki has learned how to apply radiation creatively and no longer fears it; instead, as clinical section chief and program director of thoracic radiation oncology at The University of Texas M. D. Anderson Cancer Center in Houston, she uses it in increasingly sophisticated ways to fight cancer. She's one of the world's leading researchers and advocates of proton radiation beam therapy, an emerging treatment that many oncologists consider the safest and most effective available. And according to Komaki, her work is much better done in the context of a university program than at private institutions.
"Our patients, including all of our proton patients, are treated under clinical trials," which monitor results on large numbers of patients, she points out. "It's difficult to treat patients on trials at private hospitals or clinics. They don't have enough manpower, and they don't have review boards that can check on compliance of eligibility and maintain strict quality control of treatment. This means patients get better care here." Recently awarded the Juan A. del Regato Foundation Gold Medal for best educator and teacher, the higher education setting also allows Dr. Komaki to share her knowledge with future innovators. "I try always to educate younger people — students and trainees, as well as patients — to live healthy lives and achieve their goal to help others."
What is Proton Therapy?
Proton therapy, like other forms of radiation, aims ionizing particles (in this case, protons) onto a target tumor to damage and ultimately destroy its cancerous cells. But proton beams are much more localized and powerful than the X-rays used in more established radiation therapies. In the latter, the dosage is big enough to kill the cancerous cells, but some radiation also hits the healthy cells around the tumor. This can cause such side effects as pneumonitis, esophagitis and bone marrow toxicity, or lead to the growth of secondary cancers.
To reduce damage to healthy tissues by a scattered dose of low radiation, the oncologist requires sharply delineated radiation, and proton beams are shaped to almost perfectly match the specific tumor and aimed to strike it precisely. Collateral damage is thus minimal, making it feasible to hit the cancer with much bigger doses. In addition, photons (X-rays) release up to 90 percent of their cancer-fighting energy as they penetrate the skin, and lose 30 percent of it by the time they reach the tumor, meaning their overall effectiveness is reduced by 40 percent; they also exit out the rear of the tumor to further damage healthy tissues behind it. By controlling the speed with which it's shot into the body, the proton beam is calibrated to be at 30 percent of its maximum efficacy near the skin level while gathering full strength when it actually reaches the tumor and it barely exits the body at all.
Komaki says the treatment is most recommended for those whose localized cancer has not spread to distant parts of the body. The success rate against prostate cancer, for example, is around 90 to 95 percent. But proton therapy succeeds against many of the 130 known forms of cancer. A recent study led by Komaki and her husband Dr. James Cox, head of the division of radiation oncology at UT M. D Anderson Cancer Center, shows that proton therapy, when used simultaneously with chemotherapy to treat lung cancer, causes significantly less damage to surrounding healthy cells than other forms of radiation. It's also particularly effective for children, because it causes little, if any, collateral damage to their still-growing tissues and organs. Likewise, the elderly are strong candidates because tissues and organs surrounding their tumors are often too weak to withstand the more commonly employed radiation treatments. Dr. Komaki also stresses that the side effects are minimal, noting one patient who played a round of golf following each of his daily outpatient treatments.
"Patients think this is fabulous," she says. "You know why? They rarely get sick from proton treatment itself! 'Are you sure you're giving me the treatment?' they ask. It's amazing how much proton treatment they can tolerate compared to photon treatment."
Making Proton Therapy Accessible
When she entered medical school in Hiroshima, Komaki was taught that surgery was the only viable cancer cure. But in the 1970s — while doing her externship, internship, residency and fellowship in Milwaukee — she began learning "how radiation could cure people, and that gave it a different meaning to me than just the atomic bomb," she says. She came to view localized radiation treatment as less harmful than chemotherapy, and realized that it couldn't be equated at all with the scattered, uncontrolled radiation to the whole body that comes with exposure to an atomic bomb. In 1985, she and Cox went to Columbia Presbyterian Medical Center in New York to work with Dr. Eric Hall, then a leading international authority on the effects of the atomic bomb on humans. In 1988, she began putting her years of research to work at UT M. D. Anderson.
Though protons were discovered by Ernest Rutherford in 1919, proton therapy didn't commence until 1954, at Berkeley nuclear physics labs. The Harvard Cyclotron Laboratory partnered with Massachusetts General Hospital to begin treating cancer patients in 1961. But the necessary technology is so expensive that treatment remained confined to physics research labs until 1990. That's when the Proton Treatment Center opened at Loma Linda University Medical Center in southern California to offer the first hospital-based program.
Intrigued by the proton therapy research then available, Komaki and Cox visited Loma Linda early on, and began to push for a similar unit at UT M. D. Anderson when they returned to Houston. Their efforts paid off in 2006, when the $125 million Proton Therapy Center opened its doors offering a complete range of proton treatments. It's the only such facility in the Southwest. (In addition to Houston and Loma Linda, the nation now has centers in Florida, Indiana and Massachusetts, with several more being planned.) Today, Komaki and her colleagues treat thoracic malignancies — therapy that requires a team of seven doctors, several physicians and dosimetrists and a couple dozen technicians — in 10 to 15 patients daily, with four of them taking proton therapy. Like other radiation treatments, proton therapy runs about seven weeks. In all, the Proton Therapy Center, with Dr. Andrew Lee as medical director, treats 75 to 80 patients daily.
To Komaki, this is just the beginning. "Our physicists have already made a machine here that creates a scanning beam," she says. "We're the only place in the world with a scanning beam, which means we can remove neutron contamination." (Neutrons are created when protons enter the body; though it happens rarely they can cause secondary malignancy a decade or more later.) She also believes that proton therapy is extremely important to the future of cancer care. "These patients are already sick from cancer," she says, "Why make them get sicker from treatment? Now, we can make them more comfortable — killing cancer cells but not killing normal cells. Now, they can live a normal life while getting treatments." Whatever happens next in this field, Dr. Ritsuko Komaki and her colleagues at UT M. D Anderson are likely to be at the forefront.
Categories: Education, Interactive/Website, Writing Sample
There is a Moment – University of Texas
Thought Leadership Blogs: Trendline Interactive
Share the Air PSA Campaign
Shadow Healer Graphic Novel
Fresh Art International Interview on NPR
Email Marketing: How Hard Can It Be?
NXP Electrification Solutions Video


text:
from orgmode import echo, echom, echoe, ORGMODE, apply_count, repeat
from orgmode.menu import Submenu, Separator, ActionEntry
from orgmode.keybinding import Keybinding, Plug, Command

import vim

class Example(object):
	u"""
	Example plugin.

	TODO: Extend this doc!
	"""

	def __init__(self):
		u""" Initialize plugin """
		object.__init__(self)
		# menu entries this plugin should create
		self.menu = ORGMODE.orgmenu + Submenu(u'Example')

		# key bindings for this plugin
		# key bindings are also registered through the menu so only additional
		# bindings should be put in this variable
		self.keybindings = []

		# commands for this plugin
		self.commands = []

	@classmethod
	def action(cls):
		u"""
		Some kind of action.

		:returns: TODO
		"""
		pass

	def register(self):
		u"""
		Registration of the plugin.

		Key bindings and other initialization should be done here.
		"""
		# an Action menu entry which binds "keybinding" to action ":action"
		self.commands.append(Command(u'OrgActionCommand',
				u':py ORGMODE.plugins["Example"].action()'))
		self.keybindings.append(Keybinding(u'keybinding',
				Plug(u'OrgAction', self.commands[-1])))
		self.menu + ActionEntry(u'&Action', self.keybindings[-1])

# vim: set noexpandtab:


text:
Past six days
THE TIMES DIARY
A rum deal for sailors
Saturday August 01 2020, 12.01am, The Times
The Royal Navy has been sober for exactly 50 years. Since the final pouring of the daily rum ration on July 31, 1970, alcohol has never passed a sailor's lips on duty. Well, hardly ever. It is surprising it lasted so long. The Admiralty's wonderfully named Grog Committee proposed banning the daily tot, equal to two doubles, way back in 1850. In a Commons debate on the abolition 120 years later, one James Wellbeloved, a Labour MP, argued that, far from impeding performance, a glass of rum helped to stabilise a sailor's stomach in stormy waters. Despite Wellbeloved offering "sippers or gulpers" to any MP who backed him, his attempt to block the ban was scuttled by the government.
The BBC has tried to make


Design of Experiments Lecture 2 1. 1 Design of Experiments Simplified (DOES) Presented By: Juanito S. Chan, PIE 2. 2 Rationale In any manufacturing setting, processes are governed by different variables that can affect the overall performance of the different processes.... 13.8 Design • Design: An experimental design consists of specifying the number of experiments, the factor level combinations for each experiment, and the number of replications.
Several experimental design and optimization techniques, such as fractional factorial designs and response surface methodology, are becoming more widely used in chemical research and industry.
Quick Guide: Experimental Design for Dummies - iMotions. Imotions.com Experimental design (aka DOE = design of experiment) is a rigorous method, regarded as the most valid and unequivocal standard for testing a hypothesis.
QUALITY PROGRESS I APRIL 2005 I 59 Design of Experiments For Dummies by Willy Vandenbrande espite all the efforts by specialists in quality and statistics, design of experi-ments (DoE) is still not applied as widely as it could and should be.


"Heading into the season I'm certainty nervous," he admitted to SHORT TRACK MUSINGS. "I have NO seat time in a late model at all. Fortunately, I do have a race under my belt in a super late model, which was a great experience, even though we didn't get to finish that race from a mechanical failure.
The decision to move into the APC Series was an easy choice for Lake, in seeing the growth the Pro Late Model division has experienced over the past couple years.
"I am the type of driver where I enjoy rubbing fenders and a textbook bump and run are fair game; it's short track racing after all," he said. "However, the last couple of years in super stocks, it's been no secret I haven't been having much fun as the racing and overall attitude on and off the track has been plain disrespectful. We all work way too hard to make the cars presentable and turn the corners to race that way, and frankly, I was tired of it and needed to move on.
Knowing the level of competition he is up against and the fact he enters the year without any seat time, he is hoping to be a top-10 contender across the province.
As noted, the competition level of APC is at an all-time high with returning champions and race winners, including J.R. Fitzpatrick, Andrew Gresel, and Jake Sheridan, among the several others.
"They know their stuff and they all can wheel a car, no doubt about it," Lake commented. "They have all figured out how to finish these races and are running up front at the end more often than not. For me, getting all the laps in and finishing every race is obviously crucial to development and becoming a contender and not just a car in the field. Nothing pays dividends like race condition learning experience. Everyone out there can turn a fast lap on their own, not everyone understands setting up a pass and working through the field with a fast car.
"Late model racing as a whole in Ontario is interesting this year. It's a mix of a lot of guys moving into brand new equipment and selling off their good used stuff. There's years and years of experience, and some with no late model experience and some with no racing experience at all. It's certainly going to be a trying time as people learn what these cars are capable of as well as what the drivers are capable of.
The APC Series schedule will be hitting five different tracks across the province for 10 races, including a pair of events at Jukasa Motor Speedway.
"Well, I think everybody and their brother are excited about Jukasa," Lake said. "It's such a premier facility that you always look forward to getting the chance to race there. I have always enjoyed my time at Sauble (Speedway) as well. It's tighter, but can be racey.
Alternatively, Flamboro Speedway and Sunset Speedway bring up some butterflies, based on past race experience.
For Lake, he has been surrounded by racing his entire life, named after Darrell Waltrip with his birth announcement racing-themed.
"I was driving a go-kart and parking lots at the age of 5, racing by the time I was 9 and realized I was in the street stocks which evolved to super stock for 14 years, not the 12 I had initially thought," he commented. "Genuinely, racing is in my blood. I may be able to fall asleep in the car on pit road before the race, but it's my own way of getting focused and mentally prepared for each race before they actually begin. I am extremely fortunate to have parents that love racing as much as we do and allowed me that freedom growing up. I think starting racing young helps develop a driver and a person faster. You mature quicker and learn responsibility from a young age.
Through the years, there's been several moments that stand out for Lake's career. However, the most memorable would be his first career Street Stock victory.
LDS is a class act!


text:
The parking lot sends a strong statement about a property, both commercial and residential. A beautifully done parking lot is appealing and creates a welcoming environment for visitors. Such parking lots instill a sense of confidence in anyone that intends to drive into the property. Being one of the areas that visitors first interact with, it is a good idea to always ensure that your parking lot is in its best condition. A good parking lot also boosts the curb appeal of the premises. For generations now, parking lot striping has remained a popular way of highlighting the beauty and elegance of a parking lot. What many do not understand however is that parking lot stripping is significant in several ways other than aesthetics.
One of the noteworthy benefits of parking lot stripping is that it enhances safety on and around the parking lot. It helps in ensuring the safety of both pedestrians and drivers that use the parking lot. Clearly defining the crosswalks makes it possible for pedestrians and drivers to look out for each other and safely reach their destinations. Stripping also helps in directing flow of traffic on the parking lot. With the lines, you can indicate the lane for cars entering the parking lot and the lane for those that are leaving. The stripping therefore enhances the safe maneuvering of vehicles into and out of the lot. Besides the safety, the lines also helps in minimizing traffic jam on the lot as each car knows its corresponding lane.
Maximized Parking Space
Proper organization of a parking lot increases the parking space considerably. This is one of the reasons parking lot stripping is fast gaining popularity among property owners. When the parking spots and stalls are clearly marked with lines, it becomes easier for users to identify the right way to park. This makes it possible for the maximum number of vehicles to park all at the same time. Parking lot stripping averts situations in which illegal parking of vehicles causes congestion and inhibits parking of other vehicles which in turn limits the parking space. You should mention to the parking lot striping companies the maximum number of vehicles expected on the parking lot to help with designing and stripping of the lot.
Visual Allure
Beauty is another important benefit of parking lot stripping. A parking lot that has just been stripped looks a lot better than one that is not stripped. The stripping also makes it look a lot organized which increases its beauty.
The handicapped should be considered during the construction of a parking lot. Stripping is an efficient way of creating special parking areas for the handicapped. It makes it easier for them to identify the parking spots designed for them, making navigation easier.
When searching for ideal parking lot striping near me, Long Island Paving Masonry should definitely be at the top of your list. Delivering brilliant services in Suffolk County, Long Island and Nassau County areas, we are a company that is committed to delivering the finest parking lot stripping services. With our services, you can rest assured of state of the art stripping services.


text:
AlKhaleej Today
Who voted for Salah in the award for the best player...
International Tuesday 18th January 2022 12:44 PM REPORT
T + T – normal size
Polish striker Robert Lewandowski of Bayern Munich won the FIFA award for the best player in the world in 2021.
While Mohamed Salah, the star of Egypt and Liverpool, won the third place in the award after Messi and Lewandowski.
How was the distribution of votes obtained by Salah?
In the beginning, each country has the right to vote 3 times, with one vote for the coach of the team, one vote for the captain of the team, and one vote for a media person from that country.
It is forbidden for any player to vote for himself.
The first place in the vote gets 5 points, the second gets 3 points, and the third gets only one point.
Salah won 223 votes in the race, divided into 63 votes in first place, 75 votes in second place, and 85 votes in third place, according to Egyptian media.
Who voted for Salah in first place?
Quaid-e-Armata Wolfstein Waqt – Walton Walderman Vilburni Vagniana Vijayawana Viljavania Vilbunda Vibiru Vaskatlanda Vyssyra Vissaria Wutzija Wijimbabwe
As for the coaches, Egypt, Tunisia, Palestine, Yemen, Lebanon, Angola, Antigua and Baroda, Barbados, Botswana, Djibouti, Dominica, the Faroe Islands, Gambia, Grenada, Indonesia, Kazakhstan, Lesotho, Mongolia, Namibia, Nepal, Papua New Guinea, the Philippines, Switzerland, Tanzania, Thailand, the Turks Islands, and Turks, voted for Salah in first place.
media people
As for the media professionals who voted for Salah, they are from Egypt, the UAE, Saudi Arabia, Palestine, Jordan, Kuwait, Libya, Chad, Gibraltar, Guinea, Israel, Malta, Namibia, Scotland, South Sudan, Tanzania and Kyrgyzstan.
Follow the sports statement on Google News
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It is also worth noting that the original news has been published and is available at saudi24news and the editorial team at AlKhaleej Today has confirmed it and it has been modified, and it may have been completely transferred or quoted from it and you can read and follow this news from its main source.
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Jeff King
I am Jeff King and I'm passionate about business and finance news with over 4 years in the industry starting as a writer working my way up into senior positions. I am the driving force behind Al-KhaleejToday.NET with a vision to broaden the company's readership throughout 2016. I am an editor and reporter of "Financial" category. Address: 383 576 Gladwell Street Longview, TX 75604, USA Phone: (+1) 903-247-0907 Email: [email protected]
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2007, according to a new report published this week by UK Energy Minister Brian Wilson.
The global offshore renewable energy market could be worth £8 billion by2007, according to a new report published this week by Energy Minister Brian Wilson.
Publishing the World Offshore Renewable Energy Report 2002-2007, Mr Wilson said: 'The UK must not waste the opportunity to be world leaders in the expanding global offshore renewables market.
The World Offshore Renewable Energy Report 2002-2007 was commissioned by Renewables UK, which the minister established to help create a supply chain for renewables technologies as well as promoting exports.
The report estimates that the scale and sheer number of offshore wind developments makes it the largest sector accounting for over 97 per cent of the forecast expenditure.
The report also found that annual global offshore wind installations will exceed 900 MW by 2007. Though Denmark has the current lead with a forecast of 300 MW over the period 2001 to 2003, the removal of government subsidies means the UK will become the next major growth market. It also found that the UK is expected to install 907 MW of wind installations, which is 21 per cent of the global new capacity, by 2007.
Speaking at the Strategic Alliances in Wind power conference, which encourages companies from different backgrounds to diversify into wind power, Mr Wilson said: 'Globally, to date, less than 100 MW of offshore operating capacity have been developed. The report suggests that globally 900 new MW of offshore operating capacity will be added each year by 2007 and more importantly that the UK can play a huge part in this expansion.


text:
Pia Wurtzbach is the new #QueenoftheCentury!
By mixofeverything blog July 24, 2017 Century Pacific Foods Inc, Century Tuna, Century Tuna Pia Wurtzbach, Greg Banzon, Pia Wurtzbach
The Queen of the Universe is now also the Queen of the Century, Century Tuna that is, the country's number one tuna! Pia Wurtzbach – ever gorgeous TV host, model, and Miss Universe 2015 no less – joins Century Tuna's outstanding roster of endorsers, as she appears in an all-new TVC that's oozing with sexiness and elegance!
"We're thrilled to have Pia Wurtzbach in the Century Tuna family," beams Greg Banzon, Century Pacific Foods, Inc. General Manager. "Pia is indeed 'The Queen of the Century,' the epitome of a mutli-faceted woman who excels in a variety of fields while staying fit and sexy."
Pia first got bitten by the acting bug at the tender age of four, which later led her to join the Star Circle Batch 11, appearing in a string of television shows and movies. But her real break came when, in her third attempt, she entered the Binibining Pilipinas Pageant in 2015, the stepping stone to her most glorious achievement thus far: bagging the highly coveted Miss Universe 2015 crown – following in the heels of Gloria Diaz in 1969 and Margie Moran in 1973 – in what was a most contentious competition.
Together with, of course, her ravishing looks---her poise, style, and grace—her talents and intelligence, it is Pia's commitment to self-discipline and physical fitness — just look at her lean and Ultimate Superbody! — that brought her into the Century Tuna fold.
In fact, with a help of a personal trainer, Pia heads to the gym regularly, where she engages in a combination of planking (the best exercise for a flat, toned stomach), tricep pull-downs (for well-defined arms as well as shapely biceps and triceps), as well as squats and lunges (for firm and strong looking legs).
Naturally, a healthy, balanced, yet satisfying diet comes hand in hand with her exercise routine. And for this, there's nothing else but Century Tuna — the 100% winner in tuna — of which Pia has been a long time fan. "I have a busy schedule and always on the go so when I do have the time to grocery shop or prepare a meal, I make it a priority," relates Pia, who, unbeknownst to many, studied culinary arts. "I like to enjoy food that keeps my energy levels stable, like Century Tuna."
Because of Century Tuna's versatility, where it can be used in a myriad of yummy and nutritious dishes, Pia need not deprive herself while becoming the ultimate superbod. After all, Century Tuna is made of 100% real tuna, rich in Omega 3 DHA, which helps you achieve a healthy and 100% winner superbody, just like hers!
"I've always been a Century Tuna girl! And this body you see is made possible by Century," Pia continues.
No doubt, Pia Wurtzbach has become an inspiration to many and a true role model, the perfect embodiment of Century Tuna's winning ways and her role as the new Queen of the Century! Hail to the Queen!
Century Pacific Foods Inc, Century Tuna, Century Tuna Pia Wurtzbach, Greg Banzon, Pia Wurtzbach


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