But today I am still in my Sunday mood and have planned a nice day with friends and family. After publishing that post I am off to Munich to meet Kristin for brunch. I am looking forward to catching up as we haven't seen each other since Vienna. That's been early December. In the afternoon it's my little niece Victoria's Birthday. She turned 1 year last week and we're celebrating huge! She had a rough start to her life and over a course of a few weeks we didn't know if things would turn out in our favor. But she's a tough little girl and she does great! She always laughs, smiles and is happy! So there will be a huge party today 🙂 Her life is certainly worth celebrating! But first I will participate in Arman's Spill it Sunday link-up!
This topic really hit home here. I am so excited to share with you my wonderful taste of TV series. No kidding I just love me my trash TV too much. This is going to be a bit of a rollercoaster now so please take a seat and get a grip we'll take off soon.
-> What was your favourite TV series growing up?
I can't decide! No way. I always was and will always be a TV junkie and I can't say one. And then there are probably some you all don't know as they are German. But I was a huge fan of anime (the good kind) like Kickers, Captain Tsubasa, Little Women, Rose of Versailles.
-> What is your current favourite TV series?
-> If you could guest star in ANY TV show, which would it be?
If I have to choose one that is still being produced I would say The Big Bang Theory. Sheldon is just the best!
-> What genre of television do you enjoy the most?
I would say crime. I love an intelligent crime plot and enjoy following these stories more than others.
-> Which TV series do you think deserved to be renewed yet was not?
Dead like me! It was a shame that there wasn't a third season. The plot was not finished and the series was quite enjoyable,too. But unfortunately it got too pricey for the studio and wasn't renewed. The attempt of a movie was the worst thing they could do. The plot is horrible and they should just have left it at that.
-> If you could be friends with any TV character in real life who would this be?
Definitely Rick Castle! A funny, intelligent, slightly eccentric and handsome guy with a love for a good story and coffee!
I've never heard of half of these shows!
Hold on… that is NOT your dvd cabinet. Tell me it isn't. I spy Friends, Big Bang Theory, Castle, Roswell, Gilmore Girls, The Mentalist. 😯 Love those.
and The Big Bang Theory. I've basically heard great stuff about all of the rest and would probably love them.
Being a guest star with Sheldon would be so fun. You could be like his new assistant or something.
Agreed about Dead Like Me. My dad and I watched that show together and it was just phenomenal. I never watched the movie because I heard it was so awful and I was worried it would ruin my impression of the show.
Good idea with the last question! Rick Castle would be at the top of my list too. I think I'd have to pick Rory on Gilmore Girls though. She seems like she would make a great best friend.
Guilty – that is indeed my dvd cabinet 😉 I am obsessed – I warned you!
I would recommend to watch White Collar – Neal Caffrey is just too gorgeous and the series has a great sense of humor.
Don't watch the Dead like me movie – I wish I never had! I totally spoils the whole great show!
I think White Collar has one of the actresses from Saved by the Bell, right? I've heard White Collar is great. And I think it's on Netflix! My list is getting too long with potential tv shows… Darn you Arman. haha.
Yeah Tiffani Thiessen is starring. I definitely found some shows I have to check out as well! As if my dvd cabin wasn't already crammed…..
OH! You've brought back so many memories- Germany and Iran both got alot of their cartoons from Japan and just translated them- I used to LOVE watching them whenever I travelled to Iran as a kid!
Gilmore Girls I watched once and it put me to sleep…too much talking lol! And gossip girl…best ever.
Love me some VD! The books came out when I was in high school, and I still had them! I tried to re-read them and they were so awful…but the show is delicious in that popcorn way. And they move at breakneck pace and don't pull punches-there's like 5 big game changers per episode.
Yeah good-evil -good-evil, dead-alive-dead-alive if you ever miss 5 minutes you're completely clueless with whom to side! Great fun!


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EARLY ACCESS SCOUT
Latest Steam Previews
May 20th, 2014 by Jonathan Fortin
Respawn removes game modes from Titanfall's PC version, causing fan outcry
Last Thursday, Respawn removed Capture the Flag and Pilot Hunter from the PC version of Titanfall.
Said Respawn:
We have an amazing and large PC audience with the vast majority of users predominantly playing Attrition and Hardpoints game modes. CTF and Pilot Hunter have not been widely used modes on the PC version. Players trying to access these modes had overlong wait times to find other users and it was making for a poor experience. We want to make sure that not only is there compelling content in the playlists we offer, but that the experience of joining a match works well. We're tracking what playlists players are choosing, and we're going to continue to look at unpopular playlists and add new ones on both platforms.
However, since then, many fans have cried out their disapproval throughout the internet.
The statements made by Respawn seem to have only added fuel to the fire, as well, as Respawn's attitude seems to be, "Since you have to wait five minutes to play your favorite game mode, why don't we just remove it altogether? It's for your own good. Honest." Making matters worse is that CTF and Pilot Hunter have been replaced with two new game modes, which require you to purchase the recent Expedition DLC. Not only does that cost money (essentially making you pay to get the same amount of content that the game had when you first purchased it), it also requires navigating through Origin's clunky interface.
Titanfall's website continues to list CTF and Pilot Hunter as playable game modes, without any mention that they are absent from the PC version. Some fans wonder if new PC players will purchase the game and wonder where these game types are, ignorant of their removal due to the game's dishonest marketing.
It is worth noting that the Xbox One and Xbox 360 versions of the game remain fully intact.
Perhaps soon Respawn will listen to the fans and bring all of Titanfall's game types back to PC. We'll see.
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TN HB0695 Intro As introduced, creates sales and use tax exemption for sale of public safety and public works-related goods to certain nonprofit property owners associations. - Amends TCA Title 67, Chapter 6, Part 3.
TN HB1146 Intro As introduced, increases the number of free plates from one to two for the Purple Heart and disabled veteran license plates issued to veterans with disabilities. - Amends TCA Section 55-4-256 and Section 55-4-257.
TN HB0966 Pass As introduced, authorizes the development and use of a commemorative certificate of nonviable birth. - Amends TCA Title 63 and Title 68.
TN HB1154 Pass As introduced, adds the word "valor" to the Silver Star specialty license plate. - Amends TCA Title 55, Chapter 4.
TN HB1148 Pass As enacted, designates June 27 of each year as "Post-Traumatic Stress Injury Awareness Day," a day of special observance. - Amends TCA Title 15, Chapter 2.


In this cost-free on-line music small business lesson, Berklee On the internet study course author, instructor, and Main Promoting Officer Mike King discusses the finest practices for on-line music advertising and marketing. He is joined by Berklee Online's Director of Admissions, Michael Moyes.
Mike King is a study course author, instructor, and the Assistant Vice President for Promoting and Recruitment / Main Promoting Officer at Berklee On the internet, the on-line continuing instruction division of Berklee Higher education of Music. Prior to doing the job at Berklee, Mike was the Promoting/Product Supervisor at Rykodisc, wherever he oversaw advertising and marketing attempts for label artists like Mickey Hart, Jeb Loy Nichols, Morphine, Jess Klein, Voices On The Verge, Monthly bill Hicks, The Slip, Pork Twister (Phish), Kelly Joe Phelps, and Frank Zappa's estate. Mike was the Director of Promoting and Managing Editor of Herb Alpert's on-line musician's resource, www.artistshousemusic.org, for three several years.
Mike has created and teaches 4 programs for Berklee On the internet: On the internet Music Promoting with Topspin Music Promoting a hundred and one On the internet Music Promoting: Marketing campaign Procedures, Social Media, and Digital Distribution and Music Organization Developments and Procedures. His guide, Music Promoting: Press, Marketing, Distribution, and Retail was revealed by Berklee Press in 2009. Mike was identified as the Greatest Music Organization Teacher by the National Association of Report Business Specialists (NARIP) in 2011.
Mike has created for Generating Music magazine, Global Musician, Hypebot, and American Songwriter, and has been quoted in NPR Early morning Edition, The Huffington Article, Billboard, The Boston Globe, Wired, CNN, The Boston Phoenix, The Chicago Tribune, Music Relationship, and Muso. He is also introduced at MIDEM, CMJ, SXSW, NAMM, NARM, SF Music Tech, Futures of Amusement @ MIT, and Music 2..


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Embarrassing Duels
In June 1836, congressmen Daniel Jenifer of Maryland and Jesse A. Bynum of North Carolina met on the dueling ground in Bladensburg, Md. Jenifer had denounced Andrew Jackson's party and refused to retract his statement. The two men stood 10 feet apart, both fired six times, and, amazingly, both missed six times. They called it a draw.
In The Field of Honor, his 1883 history of dueling, Benjamin Cummings Truman records a strange contest between Capt. Raoul de Vere and Col. Barbier-Dufai, of Paris. The two agreed to settle a quarrel by entering a coach with daggers in their right hands and with their left arms tied, and fighting while the coach was driven twice around the Place du Carousel. Both died.
Even stranger: A Spaniard and a German both loved the daughter of Maximilian II, but the emperor did not want to risk their lives in a conventional duel. Instead he promised the girl's hand to whichever man could wrestle his opponent into a bag.
"The two gentlemen expressed their willingness to engage in even so ridiculous a contest for so superior a prize, and fought in the presence of the whole court, the contest lasting more than an hour, the Spaniard finally yielding, having been put fairly into the bag by the German, Baron Eberhard, who took it and its Castilian contents upon his back, and very gallantly laid them at the feet of the young lady, to whom he was married the following day. This is the only duel or tournament of the kind on record."
See En Garde!
July 4, 2010 July 4, 2010 | Society
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*For 12 pastries, thaw 1 sheet and halve the rest of the ingredients!
Defrost the puff pastry sheets overnight in the refrigerator. Unfold the sheets of puff pastry on a lightly floured surface. Roll out the sheets to 12 x 12 in size. Cut 12 3-4 inch circles per sheet (24 total with 2 sheets) and discard any scraps.
Make an inner circle about 1/16 inch in from the outside edge by cutting the pastry but don't cut all the way through the dough- just score the dough. This will allow the dough to rise and to form a crust. Inside the inner circle using the tip of a fork pierce the dough 10 times to allow air to escape in the inside circle. Place the circles on cookie sheets lined with parchment paper and refrigerate until it is time to use them.
Over a medium heat, warm the three tablespoons of olive oil and add the onions. Sauté the onions for about 20-25 minutes stirring occasionally until caramelized and there is no moisture in the skillet. When the onions are caramelized, add the garlic to the onions and sauté for 1-2 minutes more. Add the ¼ cup of white wine and then add 1/2 teaspoon salt, 1/4 teaspoon pepper, and the minced thyme. Continue to cook for 3-8 minutes more and all the moisture has evaporated again. Remove from the heat and set aside to cool completely.
Once cooled, remove the pastry circles from the refrigerator. Distributing evenly among the 24 pastries, sprinkle the grated Parmesan on each round, staying inside the inner circle.
Divide the onion mixture evenly among each of the pastries and place on top of the parmesan cheese but stay within the inner scored edge.
Next, crumble and divide the goat cheese among the pastries and place on top of the onion mixture.
Then take a few slices of the tomatoes and lay two slices on the goat cheese. Brush or drizzle the tomatoes with a little olive oil using a pastry brush.
Finally, distribute evenly among the pastries the julienned basil and season each pastry with a little fresh ground pepper.
Using a micro-plane, grate the parmesan cheese and a sprinkle over each pastry as a final decoration and fantastic topping flavor.
Bake for 20 to 25 minutes, the pastry will be a golden in color. Halfway through baking switch the sheets by rotating 180 degrees and swapping the bottom and top sheets for even baking.
*** They can be prepared 24 hours in advance uncooked and assembled except don't brush with olive oil, basil pepper or micro-planed cheese until they ready to be placed in the oven. In order for the pasty to puff, they need to be cold!


We really like bread, garlic bread, and yes, we really like cheese. So what better recipe than one that puts them all together and gives you a delicious treat to eat with any homemade pasta or pizza meal. This Cheesy Garlic Pull Apart Bread Recipe came from trying to think of another way to use my sourdough bread. I made a number of loaves that were eaten, and this one was a day old – which is definitely not bad, but is not fresh out of the oven. It was perfect for making into this cheesy garlic pull apart bread recipe though.
If you do not have Sourdough bread, any of your artisan loaves will do. You can even get one on discount because it's a day or so old. It will be perfect once you add the cheese and bake it again.
If you want to make your own sourdough bread, check out my How to Make a Sourdough Starter page and Sourdough Bread Recipes. There you can get into making your own sourdough and reap all the health benefits from doing so.
Once you have your bread, follow the steps below!
A yummy cheesy dish for an appetizer or to go along with any homemade pasta or pizza recipe.
With a sharp bread knife, slice the bread in strips horizontally and then vertically, careful not to cut all the way through.
Sprinkle garlic powder and salt onto the bread, careful to get it into the crevices.
Slice the cheese and carefully put the slices in the crevices of the bread.
Bake at 200 degrees F for 15 minutes.
OPTIONS: you can also add chopped chives, grilled onions, grilled mushrooms, pepperoni slices, or whatever else sounds good to you.
Muenster cheese is my very favorite! My family loves it when I make artisan bread, and the combination of the two looks fabulous! Thanks for sharing. Pinning, tweeting, stumbling, and sharing on my FB page today.
Hi Kelly! This bread sure does look good. I'm still remaking our old unhealthy favorites into healthier versions and this recipe is just what I need. I can't wait to try it. We sure do love cheese in our house.
This looks so yummy! My family loves bread. I was gluten free for a year that ended recently (health issues, not a trendy diet) so I am making up for lost time, and this looks like a great way to do that!!
My family would LOVE this! I love that it uses a pre-made loaf. I'm always looking for quick sides that taste homemade, but aren't totally! Pinning!
Yes, this, croutons, and garlic toast are my go to's for if a loaf I've made doesn't get eaten right away. Like you said, it's nice to pull together for supper when you're not doing it from scratch that day.
Thanks for sharing this on Homestead Blog Hop. This looks so delicious. I will be making this!
I need to get some muenster cheese. This looks so yummy and beautiful. What a great appetizer or side!
Garlic bread goes so well with almost any meal. Thanks for sharing your recipe with Real Food Fridays. Twitted!
Thanks. What a simple idea. Basically just bread and cheese, but sometimes a fresh presentation really makes food seem special.
Thanks for another great sounding recipe. If it is anything like the Monkey Bread, we're gonna love it.
Thank you so much Rhonda. I hope you really enjoy them.
This sounds so delicious! It sounds like it would make a great side dish. Thanks for linking up at Natural Living Monday!
I love garlic bread. Thanks for sharing on Real Food Fridays. Twitted.


I'm typing this article on a personal computer. You are most likely reading it on some form of one, whether a desktop, laptop, smartphone or tablet (which are really just small computers). These amazing devices are all around us. Brilliant researchers have spent billions of dollars designing the most functional computers to help people all over the world achieve their goals. You may well know, however, that one computer is more powerful than any that humans have been able to design—the human brain. As LiveScience writer Charles Choi stated, "The most powerful computer known is the brain" (2013).
But a fresh look into the brain has revealed something amazing. This supercomputer is even more "super" than we thought. Inside the brain are short branches of cells called dendrites. These dendrites have long been thought to be simple transporters of nerve signals to brain neurons. Recent discoveries by neuroscientist Spencer Smith and his team of researchers suggest, however, that dendrites do more than passively transfer information (Choi, 2013). It appears that dendrites are actually minicomputers that process information instead of simply transferring it. Because of this discovery, Smith stated: "Suddenly, it's as if the processing power of the brain is much greater than we had originally thought" (as quoted in Choi, 2013).
To what did Smith compare this remarkable discovery? He illustrated the results in this way: "Imagine you're reverse engineering a piece of alien technology, and what you thought was simple wiring turns out to be transistors that compute information" (as quoted in Choi, 2013).
The implication of Smith's statement about alien technology could not be clearer—the brain is comparable to (but surpasses) any technology humans have designed. Therefore, if we were to realistically compare it to something, it would have to be technology produced by brilliant aliens whose mental capabilities must be far superior to that of humans. But wait, the technology that we at first recognized to be superior, we discover to be even more advanced than we originally thought. What does that say about the brain? It must have been designed by a Being with incomprehensible intelligence. The idea of mindless evolution simply cannot account for the computer, no, the supercomputer filled with minicomputers, we call the brain. It really is a no-brainer, there must be a God.
Choi, Charles (2013), "'Minicomputers' Live Inside the Brain," LiveScience, http://news.yahoo.com/minicomputers-live-inside-human-brain-113240564.html.


These notes cover important exam question answers and are strictly as per the revised syllabus of Mumbai University. Sincere efforts have been taken by authors to cover most of the syllabus of Electronics Engineering (Semester 6).
Question papers includedMay 2014Dec 2014May 2015Dec2015Solved previous question papers for Comp..


The Clean Bedroom has added a new, more affordable, innerspring mattress line to its product array: the Naturally Organic Classic, Ergo and Luxe models. Each line features organic and natural components and is engineered to provide a healthy night's sleep on a mattress with a more traditional feel and look than the rest of the company's offerings.
The Naturally Organic brand has been exclusive to The Clean Bedroom for years and has earned a good reputation for comfort, quality and price. This new mattress line offers even more affordability with queen mattresses starting at just $1,999.
The Classic features a continuous coil system with organic cotton and organic wool. The Ergo and Luxe feature a pocketed coil system, both with organic cotton. The Ergo contains organic wool as its fire barrier, while the Luxe features horsehair.
Stop into one of the company's sleep showrooms for a test rest on a more affordable Naturally Organic spring mattress. Currently available in The Clean Bedroom showrooms in Greenwich, Connecticut, Wellesley, Massachusetts, and Portland and Kittery, Maine. The line will be available in the New York City showroom soon.
For more information, visit TheCleanBedroom.com or nearby showroom located at 444 Washington St., Wellesley.
Karen Parker Piedra, a realtor, reiki practitioner and feng shui healer, will present a workshop on clearing energy in the home environment from 6:30 to 8 p.m., June 16.
The thyroid gland's hormone production and control is quite complex, yet often physicians use only the most basic thyroid stimulating hormone (TSH) test which doesn't really tell the whole story.
The female hormonal system can be compared to a symphony orchestra. If one instrument in the orchestra is out of tune, it can negatively affect the quality of the music produced by all of the instruments.
The Clean Bedroom has added a new, more affordable, innerspring mattress line to its product array: the Naturally Organic Classic, Ergo and Luxe models.
Lubrigyn line of feminine care products now at CVS Pharmacy locations nationwide.


Trifecta Dark Indian Kheer Review By Sean K.
Hey guys! Sean from CSR here. If you've ever had questions about an order, there's a good chance we've spoken! I'm the first person to admit that I'm just not that big of a fan of most dessert shisha tobacco flavors. In my experience, I find the flavor to be entirely too sweet and doesn't really capture the true nature of the dessert.
After trying Trifecta Tobacco's Indian Kheer from the dark leaf blend, I can 100 percent say that there is now a dessert flavor I like - no - love! I'm not quite sure how they did it, but the geniuses over at Trifecta have perfectly combined earthy cardamom, sweet nuttiness, and smooth creaminess to create a shisha tobacco flavor that is fantastic, plain and simple.
This flavor is supposedly modeled after a popular rice dessert from India, which is a dessert that I've never had, but honestly it doesn't even matter what it is supposed to be. All I know is that this flavor is delicious and it can be regularly found in my sessions.
While it smokes beautifully on its own, I recommend mixing Indian Kheer with either Ventura Peach or Pulp Friction, with just a pinch of Durty Mint. All of these flavors are also from Trifecta's dark leaf blend, so definitely check those out as well!


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Coaching AnalysisDefenseSecondary
· June 22, 2017 ·9 min read
Seahawks Identity Crisis Part II: Creating Turnovers
Much has been written about the Seahawks that has nothing to do with the play on the field. Whatever the reality is in that locker room, there are more pressing football questions facing the Seahawks that must be addressed if this team is to lift another Lombardi Trophy. Pete Carroll brought a crystal clear football philosophy with him to Seattle. It helped create one of the most talented and tough teams in the NFL over the past six years. Between 2012 and 2014, the Seahawks averaged 12 wins per year and played in two Super Bowls. They have averaged 10 wins in the two years since, and have lost badly in the second round of the playoffs both times. There is evidence that the Seahawks have lost touch with the philosophy that helped them rise to the top. How they confront this identity crisis will have a far greater impact on their football fortunes than any soap opera brewing behind the scenes. In this series, we will explore different aspects of Carroll's philosophy and assess whether the 2017 Seahawks are in position to recapture their dominant formula.
"If you don't have a clear view of your philosophy, you will be floundering all over the place. If you win, it will be pure luck." – Pete Carroll USC Coaching Clinic
PART I: Offensive Philosophy
[divider]Part Two: Creating Turnovers[/divider]
A foundational element of Carroll's approach to football is creating turnovers on defense and preventing them on offense. He believes in this based on experience, as well as years of data that indicate a correlation between turnover differential and winning. There is little doubt among his players where this stands in his list of priorities.
"The first meeting that we have every year, [Pete Carroll] raises up the ball and he says, 'It's all about the ball. We've got to take care of the ball. We've got to steal it from the offense and take care of it when we have it on offense.' Those things don't change and that's probably one of the things I love most about Pete is his consistency when it comes to his philosophy." – Doug Baldwin Jr. during a recent press conference
He spends one day of practice every week of the season focused on turnovers. The team looks for innovative new ways to rip and tear at the ball to dislodge it from the ball carrier, while the offense focuses on holding the ball high and tight to reduce the risk of it getting punched free. All this attention helped the Seahawks rise to the top of the NFL in turnover margin during their Super Bowl run. That prowess has not stood the test of time.
The Seahawks have seen their turnover margin, as well as their ranking in that category across the NFL, decline in each of the past three seasons. There margin was halved the year after their first Super Bowl, and dropped even more drastically from 2015 to last year. In all, they went from being the best in the league in this area to being middle-of-the-pack. That cannot sit well with Carroll, and we know it cannot be because he is emphasizing it any less. So what is going on?
Breaking down the Seahawks turnover margin decline
Turnover margin is composite metric based on two other statistics: takeaways and giveaways. To better understand what is happening with the Seahawks on the turnover front, we first must start by examining how Seattle has done on both aspects.
You can see that there has been a negative trend for both, but the drop-off in takeaways is far more severe. In fact, the team had improved drastically in protecting the football in 2014, which masked the massive drop in takeaways. The giveaway level rose to 18 last season was still below the Super Bowl winning year. Seattle wound up being ranked fourth in turnover margin in 2014 despite taking the ball away fifteen fewer times than the previous season. That is nearly one less takeaway per game. All this is to highlight that the Seahawks are still pretty good at taking care of the ball. They also have far more control of limiting their giveaways than getting more takeaways. They should be able to reduce their giveaways by regaining some of the balance on offense with a healthier running game.
Takeaways, though…those are not so easily set aside. The trend there is disturbing both in its severity and the fact the team does not have as much control to make a difference. From 2011 to 2013, the Seahawks averaged 33.7 takeaways per season. Over the last three years, the team has averaged just 22 takeaways per season, and that dropped to a six year low of 19 last year. During that time, they went from being one of the best teams in the league at taking the ball away to one of the worst (bottom third of the league). Just like turnover margin is a compound metric, takeaways come in the form of interceptions and fumbles, so let's take a closer look to see what is going on there.
The top chart above shows that the Seahawks trouble with takeaways has nothing to do with volume of chances. They are half as likely to take the ball away on any given play than they were in 2013. The next row of charts separates that out into their efficiency for intercepting the ball per opportunity and the fumbles recovered per opportunity. Chances for interceptions only happen when an opponent drops back to pass. Fumbles can happen on any play.
Seattle has had more trouble recovering fumbles as a way to create takeaways, but the decline there is minor compared to what is happening with interceptions.
The Seahawks are nearly three times less likely to intercept a pass than they were three years ago.
That is a smoking gun in this little investigation of ours. The last row of that graphic puts the focus completely on interceptions, and we see further confirmation that the Seahawks takeaway problem is almost exclusively driven by a drastic reduction in their ability to intercept passes. In fact, their league rank in interceptions closely maps to their league rank in takeaways. Both saw them go from #1 in the league to #22 in a few seasons.
What changed? The scheme is the same. That leaves personnel, performance, and coaching as the obvious scapegoats. Both likely played some role, but there is another more insidious reason I believe this is happening.
Factors outside Seattle's control
Think back to the first road game of the 2014 season. The Seahawks played Philip Rivers and the Chargers in San Diego in sweltering heat. Time and time again, Rivers would check down to his running backs and tight ends for short passes underneath the Seahawks zone coverages. They were content to dink-and-dunk instead of trying to beat Seattle over the top. This approach was effective at moving the ball down the field with little risk of turnover. Ultimately, it helped the Chargers score 30 points and become the first team to beat the Seahawks by more than seven points in nearly three years.
Eighteen of the Rivers' 37 pass attempts (49%) went to either running backs or tight ends. Another 10 passes went to Eddie Royal, their slot receiver, who averaged just 9.9 yards per catch. That means over three-quarters of Rivers' attempts went to short targets. Statistics show those are very difficult to intercept.
Warren Sharp does some great work with advanced statistics on the NFL, and helped me find some statistical evidence to test a few of my hunches.
Turnover rates vary by type of target
Sharp has a great table that shows the propensity for turnovers by position, down and distance. The important insight is that, in 2016, passes to running backs were the least likely to result in a turnover (just 1.2%), passes to tight ends were next (2.4%), and wide receivers were last (3.2%). Sharp explained that opposing offenses threw 42% of their passes to RBs or TEs on early downs last season before Earl Thomas was injured. Everything changed after Thomas went down, but that's a separate article. The point is that opposing offenses are throwing to safer targets, and ones that are not typically defended by some of their strongest turnover creators like Richard Sherman. They also are not attacking downfield as much.
Source: Sharp Football Analysis
This table shows the average depth of target against defenses in the first 11 weeks of the 2016 season. You can see that the Seahawks saw the third-highest percentage of passes (52%) within six yards of the line of scrimmage. Even if those are going to receivers, they are very difficult to intercept.
Avoiding Sherman and Thomas
Not only are teams throwing short and to running backs and tight ends, they are avoiding some of the Seahawks best playmakers. Sharp has a great visualization (shown below and available here) of opponent passer rating and frequency based on both depth and direction of pass against any defense. The following shows how teams attacked the Seahawks defense when Thomas was healthy.
The vast majority of the throws are short and to the left. They avoid deep middle and deep right, and for good reason. Their passer rating in those two zones were an abysmal 9 (deep middle) and 39 (deep right) against Seattle.
"[Favoring the left side] is completely backwards from the NFL average. With a majority right handed QBs, they like to attack the right side of the field more." – Warren Sharp, SharpFootballAnalysis.com
Teams did have reasonable success attacking deep left (84 passer rating). It is not quite as simple as blaming DeShawn Shead. Remember the infamous Falcons game in Seattle when miscommunication between Sherman and Kelcie McCray resulted in two blown coverage deep touchdowns down the left side.
There is no simple fix to the takeaway problem
Unfortunately, Sharp does not yet have historical data that would allow us to look at trends in depth of target against the Seahawks. That would be absolute proof, but having watched every one of those games and seeing this data for last season, I'm convinced that a significant part of the takeaway problem is due to how offenses are attacking the Seahawks.
The team knows it. Kam Chancellor mentioned teams attacking them "underneath our zones" in a recent press conference. Carroll's philosophy has always been to take away the deep pass and force teams to string a series of shorter plays together to get down the field. Careful what you wish for. A big part of how the Seahawks generated turnovers was when teams tested them downfield either due to confidence or impatience. It takes discipline to do what Rivers did in that game. Many quarterbacks and coaches eventually want to push the ball down field, and that is when the Seahawks feasted.
Personnel likely plays another role here. Brandon Browner, though flawed in some ways, was a prodigious playmaker. He excelled both in intercepting passes and stripping the ball free. Walter Thurmond III was arguably the best nickel cornerback in the league. Having those two made it far harder for teams to avoid the likes of Sherman. That is why it was so important for the Seahawks to get quality young corners from this draft. That may be the aspect of this equation they have the most control over.
Coaching may also play a factor. Dan Quinn was fabulous at scheming and play calling. Kris Richard has not yet proven he has a plan for how to adjust to what the Seahawks are facing.
It is going to take some of Carroll's most creative coaching to help guide Richard toward a solution. This could be one of the reasons Malik McDowell was so attractive to Seattle. Adding more height to the defensive line could be part of a strategy to disrupt the short passing lanes by focusing less on getting to the quarterback on early downs and more on getting hands up to deflect passes and make it harder to see. McDowell is 6'6″, Nazair Jones is 6'5″, and Dion Jordan is 6'6″. All three were added this offseason. Shoring up the right side of their defensive backfield and their nickel corner spot would help as well.
The truth is, there may not be a silver bullet that can allow the Seahawks to increase their takeaways. Carroll's "all about the ball" mantra likely needs to focus more on protecting the football in order to create a meaningful turnover margin, and simply stay disciplined on defense. That reinforces the need to get their running game back on track.
Part three of this series will look at explosive plays, both on offense and defense.
kris richardpete carroll
Advanced StatsCoaching AnalysisOffensePassing GameQuarterbacksRunning Game
How will Shane Waldron's influence change the Seahawks Offense?
Coaching AnalysisDraftOffenseRoster OutlookThe Front Office
Can Pete Carroll fix what ails the Seahawks?
Free AgencyJohn SchneiderOffseasonPass RushUncategorized
Seattle's Confusing Mismanagement of Jadeveon Clowney
Previous Seahawks Identity Crisis Part I: Offensive Philosophy
Next For Russell Wilson, 2015 was a season of statistical glory. 2016 was different. 2016 was more important.
Mark Dewees says:
Well written as usual Brian. The change in scheme when attacking Seattle's Def is something i have noticed the last few years as well. I have also not been a huge fan of Richard so far. The quick short routes could also be why we have seen a dropoff in the consistency of pressure the last few season. Also seems that Richard likes to blitz more so maybe that is affecting it as well drawing the LBer's in and allowing the shorter routes to RBs and TE that they normally cover. Hopefully McDowell and some of the other new prospects will help with this issue.
Rich Abrahamson says:
Rich in Ohio
Success kills modern day football players. They get big contracts. get married, start families and values change. It's human nature. These guys came to this team when they were hungry and w/o a future in the NFL and succeeded at the highest level. Success messes with the mind.
The management is suffering from fear. They have hung onto the core guys too long because they are afraid that they can't duplicate their success in finding their equal replacements They fear the players more than the players fear them! That is the opposite of the Patriots way. If you loss your value to the teams winning edge, your gone! Seattle's head guys married their stars and that hamstrings your cap.
Duceyq says:
Would be interested to know what percentage of turnovers were created with blitzes and a 5 man rush or when Seattle was playing Zone vs. Man to Man. That could be a telling stat too. Thoughts?
jason wicklund says:
Good point Duceyq. I too, would like to see stats for personnel during the turnovers.
jhwick1 says:
Great point Duceyq! Those would be great stats to see.


Babies grow and learn more in their first year than they will in their lifetime, meaning the first 12 months are a crucial time for future health and development. Not only is a diverse diet of fresh fruits, vegetables, whole grains and proteins critical for brain development, research has also found that variety is key in developing a healthy and adventurous palate.
Little Foodie Club is the brainchild of Kerstin Kühn, an internationally acclaimed food writer and journalist, and obsessive foodie. Inspired by her daughter, Maxine, for whom she created a magical range of homemade baby purées, Kerstin took the plunge into mompreneurship and launched Little Foodie Club to teach more babies about healthy, adventurous eating. She has made it her life's work to help other moms (and dads) to feed their babies the freshest, tastiest and healthiest food possible even if they don't have the time or inspiration to cook it themselves. Her curated meal plans, developed in conjunction with leading pediatricians, expose babies to an evolving range of delicious flavors and organic ingredients from the very first mouthful.
All parents want their kids to be good eaters. But how can children be expected to develop a sense of taste when the very first foods they're exposed to don't have any? Fresh baby food is bright, colorful and diverse in taste and texture; qualities that not just stimulate a baby's senses but also help to develop a preference for fresh rather than processed foods. On the contrary, store-bought baby foods from jars or pouches are mass-produced and highly processed. They lack life, freshness and texture and when it comes to flavor, well, they just don't have any because they all taste the same. So babies who first learn about food from these manufactured purées, are much more likely to prefer processed, unhealthy foods when they grow up.
And that's just the start of it. Scientific research has found that some commercial baby foods contain dangerous toxins such as lead or arsenic. Studies have also shown that some manufacturers replace real food with water and thickening agents meaning their baby foods only provide a fraction of the nutrients of home-cooked baby food made from fresh ingredients.
This is why Kerstin started Little Foodie Club: to offer parents a better choice when it comes to feeding their babies. By signing up to our subscription service, we will take your babies on a culinary journey through tastes, textures, flavors and scents that will nurture their bodies, tantalize their taste buds and expand their palates for life.


In a bowl, mix together all the ingredients for the marinade. Add the chicken pieces and let them marinate for 15 minutes.Put the sweet potato starch in a large bowl. Dip the chicken pieces in the starch to coat. Set the coated pieces aside and let them sit for about 5 minutes.


FUREY: Can we trust Canada's top public servant Michael Wernick?
NDP MP, Charlie Angus, is calling on Michael Wernick to resign.
Michael Wernick is supposed to be a non-partisan public servant, but his testimony at the justice committee suggested otherwise. We now learn that Wernick will be on the"Critical Election Incident Public Panel", a government body that will tell Canadians what is "fake news".
Can we trust him? Can we trust this panel?


If I use a file name (i.e. 'autoruns.exe') as a thought name, the file name extension ('.exe') is suppressed. I rather would like to see the file extensions. What do I have to change?
I've tested this with multiple "file extension" names, including your example, and have found no issue naming Thoughts. Anything I may be missing during testing?
I think he's referring to .exe files, .doc files etc being dragged in and the extension then not being visible in the thought name.
It's a fair request, but I for one wouldn't like this feature, so if it was implemented it should be optioned in preferences.
Yes, Spacenexus is right; it happens when dragging filenames into the plex.
And yes, it would be best to make this a preference (similar to the one in Windows Explorer).
Recall also that the icons already automatically reflect file type so that image so that does already help.
I will see if this is something that can be implemented. A temporary workaround, in the meantime, is to simply rename the Thought to include the extension after the file has been added.


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Sydney Film Festival unveils first batch of films for 2013
April 4, 2013	by Simon Miraudo 0 Comments
The first batch of titles headed to the 2013 Sydney Film Festival have been unveiled on the SFF's official website.
A couple of the pictures were expected by arthouse aficionados to make the cut, including Park Chan-wook's English-language debut Stoker (which was delayed from its original March release date to instead debut at the fest), and Noah Baumbach's latest, Frances Ha.
That doesn't make their inclusion any less exciting.
They'll join SFF mainstay Takeshi Kitano's newie Outrage Beyond, Michael Winterbottom and Steve Coogan's latest collaboration The Look of Love, Sarah Polley's autobiographical Stories We Tell, and Russell Crowe-narrated Aussie doco Red Obsession.
Also found in this early announcement is Prince Avalanche, in which David Gordon Green returns to his indie roots with Paul Rudd and Emile Hirsch, as well as the Spanish Snow White flick Blancanieves, not to mention Alfred Hitchcock's classic Rear Window.
Head to the Sydney Film Festival site for the rest of the list.
The festival takes place June 5-13. The full program will be announced between then and now.
Home, News, SFF News, Sydney Film Festival
blancanieves, frances ha, outrage beyond, prince avalanche, quickflix, rear window, red obsession, sff, stoker, stories we tell, sydfilmfest, sydney film festival 2013, the look of love
Finding Nemo sequel christened Finding Dory; set for release in 2015
Teaser Debut: Only God Forgives


The Responsibility Has Its Rewards® campaign promotes traffic safety, positive fan behavior, responsible alcohol consumption, and the designated driver program at sports and entertainment facilities. Partners in the campaign include NHTSA – the U.S. Department of Transportation's National Highway Traffic Safety Administration, state offices of highway safety, professional and collegiate sports, entertainment facilities, concessionaires, stadium service providers, the beer industry, distillers and broadcasters.
TEAM Coalition partners with its six professional sports league members to offer fans and supporters the Responsibility Has Its Rewards (RHIR) sweepstakes. Fans who pledge to be designated drivers at professional sporting events are entered to win amazing prizes. Click on any of the images below to learn more about the RHIR sweepstakes.


This seminar hosted by The Reel takes a look at how to break into the world of advertising. With a panel including directors in the commercial field and representatives from some of the leading production companies in London, the panel examines what it takes to get noticed when starting out and how best to propel you career from there on.
Radar Music Videos: How Do I Find Representation?
This session takes a look at how to progress your career as a music video director through getting representation via being signed to a production and/or distrbution company. With a focus on those involved in the distribution and exhibition of music videos, this seminar is an opportunity to hear from a panel formed of leading industry professionals including agents and production companies, plus you'll also hear from directors who have recently been through the process of being "signed up".
Lee Morgan and Ryan Ackland are life-long film fans and have been friends since their school years. While at University they began to make short films together, sometimes for Uni projects, sometimes just for fun. Living in London and with some good camera equipment they are now looking to progress their skills to the next level. Ryan is currently working as a cameraman/producer for a interactive TV show and Lee is an editor/cameraman at a production company.
"Having helped out in the 2009 RSSF we were more than happy to return and help out once more, this time filming some of the events. Everyone involved with the festival are always a pleasure to work with and it's great fun, containing a huge selection of great shorts from the industry's rising stars.
Chris Crockford is Head of Projection at The Hospital Club. A passionate film lover, filmmaker and editor. Having established his reputation for skilled projection in a number of leading private cinemas in London's West End/ Soho. His settled at the Hospital overseeing the cinema's technical needs from its opening 7 years ago to the present day.


February 13th is our fifth of six events in the Internship Boot Camp series. Students can attend any of the events and no registration is required.
The "Interviewing" event consists of practicing your interviewing skills. It is important to research the position and the company you wish to intern for. Come learn more about building your interview skills for that big day.


text:
Blue light gives night diving a bright makeover
Seeking to get a more vibrant, varied fluorescence experience when viewing marine life during nighttime diving, Charles Mazel, Ph.D., principal research scientist at Physical Sciences Inc. (Andover, MA) and a scuba enthusiast, discovered that blue light delivered.
In the mid-1980s, Mazel experimented with ultraviolet (UV) light, which, while invisible to the human eye, can make marine life fluoresce. He later gained access to a spectrofluorometer, which enabled him to monitor the emission spectra of coral samples, and found that fluorescence was stronger in the blue wavelength region (450–495 nm) than in the UV. Discovering too that blue light caused back reflection that overpowers the beauty of the fluorescence, he remedied that with a yellow filter visor.
In preparation for a diving trip in the Bahamas, he built a blue light prototype using a low-powered filament bulb flashlight. There, he compared his prototype (while wearing his yellow filter visor) with the UV light that he had been using, and found that the blue light/yellow filter combo enabled him to view weak red fluorescence in chlorophyll that cannot be seen using UV light.1
NIGHTSEA founder Charles Mazel photographed a Phymanthus crucifer, known as a beaded anemone, in Pedro Bank in Jamaica. While most of these fluoresce a single color, this one exhibited intense oranges and yellows with subtle patches of green, he says. (Image courtesy of NIGHTSEA)
While on another diving trip in Bonaire, Dutch Antilles, Mazel viewed nudibranchs (known as sea slugs), a type of mollusk that sheds its shell after the larval stage and measures around three-quarters of an inch. Nudibranchs may have several utilities in medicine, as scientists have studied their simple nervous systems for clues on learning and memory, and used their defensive toxins in search of pharmaceuticals.2 Mazel was able to view a species of nudibranchs that normally looks translucent, but when illuminated with blue light appear in bright-orange fluorescence, he told BioOptics World.
Mazel's discoveries led him to start NIGHTSEA (Bedford, MA), a company that offers blue-light tools at varying price points for sport divers, researchers, and photographers, among others. In a collaboration with underwater lighting maker Light & Motion (Monterey, CA), Mazel developed the Sola NIGHTSEA blue-light underwater device, which delivers 3000 mW of radiant flux for just under two hours when submerged. A custom interference filter pops on over the light head to convert the blue light to white.
In November 2013, the partners launched the GoBe light tool, which weighs 120 g and is compatible with six interchangeable light heads—including a 500-lumen NIGHTSEA light head with a 20° beam angle and submergibility to 120 m. For more information, please visit http://www.lightandmotion.com/gobe.
1. See http://www.nightsea.com/articles/blue-light-for-underwater-fluorescence/.
2. See http://www.calacademy.org/newsroom/releases/2010/johnson_award.php.
Latest in Biophotonics Tools
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More in Biophotonics Tools
Cytek Biosciences opens offices in Japan, The Netherlands
The company's flow cytometry systems have uses in clinical research fields such as immunology and immunotherapy.
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The Aurora flow cytometer is available with up to five lasers to enable analyzing up to 40 markers simultaneously in one sample.
Biocompatible nanolaser has ability to function inside living tissues
The nanolaser, mainly made of biocompatible glass, shows promise for imaging in living tissues.
Project to develop streamlined laser setup for deep tissue analysis
The Deep Tissue project has the goal of designing a laser setup that aims to enable greater analysis of biological tissue, including skin, bone, and plant life.


I want to read Bauman's Social Europe book. Perhaps, since the book comes in non-traditional forms, this is something I will do while traveling.
I submitted something to my writing group but must not forget to do something with it once I get it back. It has potential to be overshadowed but should not.
After I finish this next paper I must keep working on it, dividing time between it, my out of field paper, and course preparation. Then the question of our grant proposal will come in, and I do not want to miss a beat now.
That means, of course, that I cannot participate in any of my typical self-destruction or self-doubt now; others need me to be whole and want to know what I have to say.
I've left Facebook, temporarily at least. This is difficult as Facebook has often been where the most grown-up conversations were (more than in life). Now, though, I am finding it fragmenting and non-meditative, so I have gone. I will visit certain blogs more regularly: Remaking the University and Blood Studies, for instance.
Also on Facebook, I've realized that there are certain secret groups I can go to for very specific purposes and bypass the rest of the things. That way I retain its humanizing aspects (resistance to the corporate university, writing accountability) and evade the noise.
On political euphemism, it is very important to note that the PATRIOT ACT (which was not patriotic) and then, rising to a new level of irony, became the FREEDOM ACT.
I read about the lives of Elena Garro and Helena Paz Garro and it was sad. Both died ill, poor and alone; Paz' death coincided with the pomp and circumstance of her father's centenary celebration. Garro's self-imposed exile had to do with the tangled politics around the events of Tlatelolco, and Paz Garro was a talented person who struggled with her parents' shadows.
Why couldn't the boy just have refused to sign the letter? Why the paralysis? For Freud, the unconscious was inherently conflictual, and in this example, the boy may have felt both the wish to sign and not to sign the letter. This would have stirred up his oedipal conflict with his father and the guilt that went with it. The symptom allowed him not to sign and, through the physical pain of the paralysis, punished him for his guilty wish.
Fraught is the word my friend used to characterize the situation at my university. Fraught is the feeling I have and fraughtness is the opposite of peace. It is the affective challenges, not the intellectual ones, that are hard.
I am involved too much, some would say, in service, administration, politics, advocacy; politics and advocacy are me and service and administration are extracted from me in a situation fraught with double binds. One should ignore everything and tend to one's work, except that those who do this, can do because they have more people to share service and administration with. And the university wants you overworked, so you cannot do advocacy and politics–and it wants you to internalize that view.
And the reason I do not like academic advice is that it ignores context. "Work in the office," it says to people who have no office (to give a simple example). Context matters. More profoundly, academic advice supposes that everything can be remedied with self-discipline and self-help; you are a neoliberal subject who, if deserving, will excel without context.
People think one should awaken in the morning thinking of discipline, schedules and getting things done, but I think one should awaken thinking of love.
Filed under ALFS presentation, News, What Is A Scholar?
Here is Weiner's smart and highly informative article, which does not discuss Denise Ferreira da Silva that I can see, but that is key. And here is a smart article about Fanon, "safety" and race dialogue that I must read.
Not for the current paper, but in general, there is a Gwen Kirkpatrick article on Diamela Eltit and the materiality of language in this book that I'd like to read as well.
These are notes on offprints I no longer need to keep in paper copies. One is Alex Flynn's piece on color in Machado de Assis, and the other is on the UNESCO study of race relations in Brazil. My marginal note on the Machado article was: "they want un-naturalized indeterminacy." What did I mean? The authors "argue that whiteness has become increasingly established in Brazilian public discourse as a naturalized category" (abstract). They see race as a process and not as a thing. (I still like the Omi/Winant concept of race as a relation.) Mixture was seen in the early 20th century as a path toward whitening and modernization. What "white" meant was less clear, but it did become a "sedimented and fixed category" in public discourse.
In any case: this article has a good review of a great deal of literature. Its primary thesis, though, is that racial categories are not fixed, and people doing the work of whiteness may not look white. I am interested in da Silva because she is not as caught up in repeating the fact that racial categories can be ambiguous and depend on place.
At the end of the summer break I will get to Houston, and I will be there in time to see what is apparently a truly important exhibit on Mexican modernism.
This of course engages my topics: avant-garde discourse (revolution, modernity), and representations of race (nation), interests I must articulate in a more precise way than I am doing at this moment.
I should hone in on all art exhibits in this way.
There are other things to remember, as well, including this inspiring article by Jacqueline Bixler on memory-theatre and Tlateloloco. Its bibliography and comments are enough to create a marvelous course and I would like to do this. And there are simple things I do not know, such that Paz' Posdata was a posdata to Tlatelolco.


text:
Q: FileUpload in form HTML I have a Website and in one webpage there is a form, where one of the fields is to upload an image. I have created in my database a column picture of type LONGBINARY. I have read some webpages where they explain how to use <asp:FileUpload ID="FileUpload1" runat="server"/>. But the doubt is that I have an input tag <input id="Submit1" type="submit" value="Put In Store" /> for my form. All the webpages where they explain about FileUpload are using a ASP button, but for my form I need an submit input.
So:

*

*What do I do if it says I need a ASP Button but I need a submit input?

*Where need to be the code of the FileUpload when you click?

My last question about FileUpload(There are the links they gave me).

A: You can upload a file using your way. Just in the form tag, do mention the type attribute type as multipart data. So when you click on Submit the request goes to the place that is mentioned in the action attribute of the form tag.
Example form tag:
<form action="demo_post_enctype.asp" method="post" enctype="multipart/form-data">

redpajama_set_name: RedPajamaStackExchange


text:
Washington Praises HM King's Role in Promoting Regional Stability and Prosperity
The United States hailed, Tuesday, the role of His Majesty King Mohammed VI in promoting stability, security and prosperity in the region.
In a statement issued on the occasion of the celebration by Morocco of the 23rd anniversary of the Throne Day, U.S. Secretary of State Antony Blinken expressed his congratulations and best wishes to HM the King and the Moroccan people.
He stressed that "this year marks the 23rd anniversary of the Sovereign's accession to the Throne as we continue to expand the longstanding and historic friendship between the United States and Morocco.
"Throughout the past year, we have continued our unwavering friendship and commend HM King Mohammed VI for his role in promoting regional stability, security, and prosperity," the U.S. diplomatic chief said.
US President Joe Biden had stressed, in a congratulatory message to HM the King on the same occasion, that the exceptional relations between Morocco and the United States continue to strengthen thanks to the solid foundation of "our common history".
"This year was marked by the celebration of the 16th anniversary of the entry into force of our free trade agreement and the holding in Morocco of the ministerial meeting of the anti-Daech coalition and the U.S.-Africa Business Summit," said the U.S. president.
-News on Western Sahara issue/Corcas


The quantity and complexity of scientific information is steadily increasing, and students are already overburdened with material to remember. Furthermore, the mere recital of facts does not increase one`s understanding of general principles. Efforts have been made to avoid overburdening the students with information. Many of the omissions are international to make the text selective. The author`s primary goal has been clear writing and meaningful figures. Yet, he has remained rigorous in his coverage of topics, believing that excess detail cannot be equated with rigour.
The book is profusely and attractively illustrated with line drawings and fine tables. I hope that this work will serve the students and teachers as an indispensable source book.
The book contains twenty two chapters and many of them are chiefly emphasized. These include - Vitamins, Feeding and Digestion, Respiration, Endocrinology, Excretion, Circulation, Nervous System, Reproduction, Muscular contraction and Thermal Regulation.


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An early career perspective on the science-policy interface in the decade of climate action following COP26
Two early-career researchers reflect on their experiences of COP26, and the bright spots for science-based decision-making in climate policy.
Faten Attig Bahar & Gaby Langendijk
This article is part of the ISC's Transform21 series, which features the latest resources from our network of scientists and change-makers to help inform the urgent transformations needed to achieve climate and biodiversity goals.
By Faten Attig Bahar and Gaby Langendijk
This piece reflects the personal opinion of the authors, and does not express the views or opinions of the affiliated institutions.
Increased heat, drought, floodings, increased wildfires, together with declining water supplies, reduced agricultural yields and health impacts in cities due to heat, are all linked to human-induced climate change. Global warming is one of the greatest threats to human existence. The IPCC's recent Sixth Assessment Report (AR6) of Working Group I made the role of humans on the climate unequivocal, and emphasized that there is still time to act, but time is running out quickly.
Five years ago, the Paris Agreement united almost all the world's nations for the first time in a single agreement on cutting greenhouse gas emissions and limiting global warming to well below 2 °C, preferably to 1.5 °C, compared to pre-industrial levels.
This year, the 26th edition of the Conference of Parties (COP26) brought parties together with the aim of accelerating actions towards the goals and implementation of the Paris Agreement under the UN Framework Convention on Climate Change (UNFCCC).
We attended the second week of the COP26. The first day at the conference was exciting. Inside the building, we were under the same roof as governmental officials, decision-makers, scientists, NGOs, and UNFCCC staff members, where big decisions that will affect people's livelihoods for the next decades were made. In the vicinity of the conference center, an overwhelming amount of peaceful demonstrators were on the streets, calling for leaders to make effective climate policy decisions, and enhance ambition to mitigate climate change. Moreover, there were pavilions from many different countries, NGOs, and intergovernmental organizations providing a multitude of presentations, panels, and briefings throughout the COP. The COP26 was a great opportunity for us to witness the climate policy process.
The bright spot during the negotiations of the COP26 was that the crucial role of science and science-based decisions was at the forefront, more than ever.
Countries' delegates frequently used "IPCC wording" in their interventions, reflecting the importance of science in the science-policy process. The first section of the Glasgow Climate Package, one of the main outcomes of COP26, is dedicated to "science and urgency", and explicitly welcomes the AR6 IPCC WG I report. For instance, the specific IPCC estimate of a reduction of 45% of GHG by 2030 is included in the mitigation section.
This increased inclusion and acceptance of climate science at the COP26 is inspiring and promising for early career researchers. It forms a great motivation to pursue a research career and to seek further impact on the policy processes by delivering high-quality, useful scientific knowledge about climate change.
Simultaneously, we also recognize that the COP26 outcomes and pledges are not enough to reach the 1.5°C target. Urgent actions are needed to implement the promises, and to enhance ambition towards stronger emission reductions.
The next decade will be critical for emissions reductions and to speed up adaptation to unavoidable climate change impacts and science can further guide this decade of action, and beyond. Climate science will continue to lay out our different futures under different emission scenarios following different levels of political and societal actions, reflecting the range of choices we have. Furthermore, climate research can and should underpin mitigation actions and mitigation target setting, as well as the evaluation of emission reduction progress. In addition, science offers knowledge-based approaches to adapt to climate change, as well as develop different futures for transforming our societies towards sustainable, equitable, and liveable futures for all. Early career researchers need to be at the forefront of these science goals, and to pioneer new methods and innovative science directions in response to COP26, as well as to find novel ways to interact with policymakers to infuse new knowledge into the policy process. COP26 sets the Earth and humanity on a new course, but only if science-based actions are actually taken. This decade is decisive.
Gaby Langendijk
Gaby Langendijk is a research scientist with a profound interest in climate change, and specifically its impact on urban areas. Currently Gaby is working at the Climate Service Center Germany (GERICS), an institute of Helmholtz-Zentrum Hereon. She has knowledge on climate and weather extremes, their impacts, and how to increase resilience through integrated, co-developed services, particularly focused on climate impacts and risks in urban areas. Previously Gaby worked at the World Climate Research Programme (WCRP) Joint Planning Staff in Geneva, Switzerland, co-sponsored and hosted by the World Meteorological Organisation (WMO). After completing a Bachelor's degree in Earth Science at the University of Amsterdam, Gaby obtained her Master's degree in Climate Studies at the Wageningen University and Research Center (WUR) in the Netherlands. She conducted her master thesis research at the ETH in Zurich, studying climate change impacts on ecosystem services in a mountainous region.
Faten Attig Bahar
Dr.-ing Faten Attig Bahar is an environmental research scientist from the University of Carthage,Tunisia Polytechnic School. She has been an Alexander von Humboldt Fellow for the International Climate Protection Program hosted at the University of Rostock, Germany (2019/2020). She was a visiting scholar at the University of Oldenburg, Germany (2016/2017). Faten serves on several continental committees including the World Meteorological Organization (WMO) Research Board on Weather, Climate, Water and the Environment, Future Earth: Steering committee of the FE Nexus KAN, the FE African community, and the FE Governing council . She is also an Executive Committee member of the Young Earth System Scientists (YESS-community). Faten has rich expertise in renewable energy technologies and implementation, energy systems modeling, climate mitigation and climate finance, green transition with a focus on emerging markets. Faten led many initiatives for young researchers and co-hosted several (online) seminars and workshops. Faten was also a reviewer of the IPCC report SOD-WGI-AR6 and SOD-WGII-AR6 and supported the work of the ECR group review of the IPCC report organized by APECS, MRI, PAGES ECN, PYRN, and YESS-community. The author of several published children's books, Faten has received several awards as an outstanding youth author.
Photo: World Meteorological Organization via Flickr.
Youth perspectives on climate 'COP' negotiations and ways to get involved
Public participation in scientific programmes: Citizen science for biodiversity
Episode 5 - Preventing Crisis: Science Diplomacy and Track Two Organizations
Episode 4 - Rebuilding Mosul's 'Lighthouse of Knowledge'
The ISC and UNEP to cooperate on advancing the use of science in environmental policy and decision-making
Science in Times of Crisis Episode 3 - The Fallout of Conflict: The Arctic and Outer Space
Ten key messages for the Convention on Biological Diversity
New from the ISC Presents podcast: Science in Times of Crisis
There are 8 years left to meet the UN Sustainable Development Goals, but is it enough time?
Special interview series on COP 27- Interview with Nick Perkins about climate change and science communication
People on the front lines of climate change must be included in climate action
Scientists and scientific organizations need to play a greater role in science diplomacy
Are we in a new era of climate adaptation implementation? The role of regional governments in facilitating local action
In the face of climate threats, we cannot afford not to act
The Role of Integrated Science in Understanding the Earth-Human System
In the face of extreme weather events, coordinated global action to address climate change is needed at COP27
Perspectives from the ISC network on expectations for the COP
Professor Carlos Lopes on why Africa needs to stick to renewables despite the temptation of gas


text:
package com.craftmend.openaudiomc.generic.voicechat;

import com.craftmend.openaudiomc.generic.logging.OpenAudioLogger;
import com.craftmend.openaudiomc.generic.storage.enums.StorageKey;
import com.craftmend.openaudiomc.generic.voicechat.driver.VoiceServerDriver;

public class DefaultVoiceServiceImpl implements VoiceService {

    private VoiceServerDriver driver;

    private String host;
    private String password;
    private boolean enabled = false;

    public DefaultVoiceServiceImpl() {
        this.host = StorageKey.AUTH_VOICE_SERVER.getString();
        this.password = StorageKey.AUTH_VOICE_PASSWORD.getString();

        if (this.host != null && !this.host.equals("not-a-partner")) {
            connect(this.host, this.password);
            this.enabled = true;
        }
    }

    @Override
    public void connect(String host, String password) {
        this.host = host;
        this.password = password;
        driver = new VoiceServerDriver(host, password, this);
        driver.setBlockRadius(StorageKey.SETTINGS_VC_RADIUS.getInt());
    }

    @Override
    public void requestRestart() {
        OpenAudioLogger.toConsole("Restarting voice driver...");
        if (driver != null) {
            driver.shutdown();
        }
        this.connect(this.host, this.password);
    }

    @Override
    public void shutdown() {
        if (driver != null) {
            driver.shutdown();
        }
    }

    @Override
    public boolean isEnabled() {
        return enabled;
    }
}

redpajama_set_name: RedPajamaGithub


Marvin's Integrity Casement windows can virtually fit into any design scheme or cater to the aesthetic needs of any home or office. Known as the ultimate form of value and quality, with nearly unlimited styling options, Integrity Casement windows offer superior craftsmanship and astounding engineering using high quality materials. Our casement windows are an excellent alternative to the traditional crank-out style awning and casement aperture. Marvin is devoted to reinventing convention, improving upon traditional techniques to provide the latest and best window products available.
Every Integrity Casement Window comes with a feature sequential multi-point locking system that makes operation simpler and easier at virtually any size. Furthermore, like many other Marvin products, our casement windows are easy to clean and maintain, utilizing revolutionary hardware which makes washing possible from the comfort of your home. Additionally, these apertures come with another form of Marvin craft and ingenuity, easy to replace jambs available in sizes as precise as 1/64 increments.
Every Integrity Casement Window is supported by Marvin Ultrex exterior technology, with a matching rich pine interior. Like other Marvin products, there are a multitude of exterior finishes and interior finishes to choose from, allowing owners to enjoy the same flexibility in style as seen in other Marvin products but still utilize these windows for their cutting-edge technology. These windows can be utilized in a variety of capacities, but they are best used for dormers, large kitchen or living room windows. Make the most of your landscape, assured by a quality product that is up to the test. Now you can enjoy nature, while being spared of its wrath.
Like many other Marvin products, these casement displays also come with a plethora of light division design features and applications. There are six different styles of light division and twenty-one different patterns available. Combined with unique interior characteristic customization, all of our Integrity Casement windows offer homeowners unlimited design possibility.
The versatility of these products have signature adaptability and exclusive utility to any home improvement project. Backed by Marvin's superior grade of products and performance parts, the Integrity Casement Window is an affordable yet unrivaled solution for any home or business owner.


text:
Kashgar är en prefektur i sydvästra delen av regionen Xinjiang i Kina. Residensstad är oasstaden Kashgar.

Historia
Prefekturen Kashgar utgjordes tidigare av Kashgariet, som genom inflytande av Yaqub Beg under sent 1800-tal var ett emirat.

Administrativ indelning
Kashgar indelas administrativt i en stad på häradsnivå, tio vanliga härader och ett tadzjikiska autonomt härad. Yarkand var tidigare en egen administrativ enhet på samma nivå, men uppgick 1956 i Kashgar prefektur.

WP:Projekt Kina

redpajama_set_name: RedPajamaWikipedia


"Main match" results from today's Steel Challenge shoot.
#merica I wouldn't want to #live in any other country in the #world cause I have seen a lot of it living some where is different versus just #hearing or #visiting it!!! #1stchoice wants our #freedoms for everyone!!!
The beginnings of my first AR10. Gotta love @aero_precision for their "blemished" parts sales! These parts are nicer than some "factory" finished parts! #ar10 #arbuild #letsbuildit #shooting #merica #trumpsupporters #leolife Just noticed I had the wrong lower box in the pic! 😂😂😂That's for another AR15 build from @80percentlowers I'll post that process later!
I'm blessed and lucky to have the best girlfriend and biggest supporter all in one 😍 I've been waiting to try Heady Topper for about 4 years + She recently surprised with a can. I decided to pop it open today after a good race and family outing.


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Uwingu does not represent either the third party or the member if the two enter into a transaction. Please be advised that you will no longer be subject to, or under the protection of, the privacy and security policies of Uwingu when you visit those links. We encourage you to review the privacy and security policies of the site you are entering, which may be different than those of Uwingu.
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Developers are a different kind of people altogether. They tend to be lazy but strive to be super efficient at the same time. A lot of this can be seen in the Android world where a certain library pops up everyday to solve a specific problem or to make the complex processes simpler.
I have a certain knack for re-using code blocks just to avoid repeative tasks and to facilitate this I usually end up converting those codeblocks into an android library.
But what if I wanted to share my android library with the world?
First of all I need to open source the andorid library, which should be easy as you can push it to Github or any other public git repository.
We will walkthrough the process of publishing to each if these central repositories in the upcoming posts of this series.
For now lets lookup the steps to publish your android library to JCenter/Bintray.
No value has been specified for property 'apiKey'.
No value has been specified for property 'user'.
Now lets setup Bintray before we can push our artifact to it.
Register for an account on bintray.com and click the activation email they send you.
and see that you have selected the option GPG sign uploaded files using Bintray's public/private key pair. and then click Update.
Now once your project is up on bintray, simply hit Add to Jcenter button to sync with JCenter.
Few things to note when you received the final email.
Once you hit sync you would see as below. Wait for few hours for the sync to occur.
The bintray and install plugins are also available on github. You may fork it and use it in your namespace.


text:
Cristiano Ronaldo Fans Cause Chaos In Saudi Arabia Days After Monumental Signing
by Rumman Rahman
Cristiano Ronaldo (Credit- Daily Mail)
Cristiano Ronaldo's arrival has created a storm in the middle east with the vibe of the player being celebrated by not only Al-Nassr but by the entire Saudi Arabian Football culture.
In a Saudi Pro League match between Al-Hilal and Al-Ittihad, two fans invaded the pitch during the match and performed the "siu", Cristiano Ronaldo's iconic celebration.
Fans doing Ronaldo's SIUUU in the game between Al Hilal and Al Ithihad. ❤😂pic.twitter.com/e295ltE7OB
— CristianoXtra (@CristianoXtra_) January 5, 2023
Al-Hilal who is considered as Al-Nassr's rival and one of the contenders for the league title won the match by 1 goal. The goal was scored by former
Al-Nassr is currently the table toppers of the Saudi Pro League with teams like Al-Ittihad, Al-Shadab, and Al-Hilal all closely behind Ronaldo's New team.
Impact of Cristiano Ronaldo on Al-Nassr
Ronaldo's transfer to Al-Nassr has gained the club global recognition with the name of the club slowly becoming a household name and being circulated throughout all football cultures.
As reported by Hypebeast.com, Al-Nassr's Instagram handle got a tremendous spike after the arrival of Ronaldo. Before Ronaldo, the club account had some 860k followers and after Ronaldo's arrival, the club has 7.6 million followers and counting.
Ronaldo's arrival led to the increase of followers of Al-Nassr's Instagram handle (Credits- Daily Mali)
Fans are much-awaited for Ronaldo's Al-Nassr debut but have to wait for a little bit more as the player is currently facing a 2-match ban as punishment for smashing an Everton fan's phone last season in the premier league while playing for Manchester United.
Ronaldo will be accompanied by some well-known players who left their mark on European Soccer. Former Arsenal and Colombian goalkeeper David Ospina is in the goal for Al-Nassr.
Colombian Goalkeeper David Ospina and former Bayern Munich player Luis Gustavo will team up with Ronaldo at Al-Nassr (source: Al-Jazeera)
Cameroon striker Vincent Aboubakar will team up with Ronaldo for the strike. In midfield two Brazilian players, Anderson Talisca and Luis Gustavo will team up with Ronaldo.
Ronaldo's arrival in the middle east has ventured into other players to consider the place to base their soccer during the climax of their career. Rumors, arising that Al-Nassr will be looking to sign more veteran players from Europe like Luka Modric and Sergio Ramos.
Tags: Al NassrCristiano RonaldoLuka ModricManchester UnitedSergio Ramos
The Lavish Lifestyle of David and Victoria Beckham's 4 Kids
Vincent Aboubakar's Contract Terminated After Cristiano Ronaldo's Arrival at Al-Nassr?
Rumman Rahman
Mykhaylo Mudryk's Controversial N-Word Video Lands Him in Deep Trouble


We were excited about getting off the plane and seeing Mary and Joe.
An adventure of firsts sprung upon us after a few months of planning. Suddenly our excursion to Florida to visit family was really happening! It was our first vacation in years. The first get away since our boys left our nest and ventured on their own journeys and Tom's first jet plane ride.
We arrived in Tampa,Florida on Saturday and Tom and I were greeted with warm friendly smiles. Right away I knew that we were far from home…warmth was a stark opposite of chilly New Hampshire Weather. Tom's sister Mary and our brother in law, Joe greeted us enthusiastically with smiles and hugs to begin our stay.
Doesn't Tom look so happy?
Their adorable home is on an approximately 2.0 acre lot adorned with palm trees in the back. A beautiful lot and yard, it's a comfortable and welcoming dwelling and we both can understand why they love it. Joe's done much carpentry work inside and out and made a front and back deck. It's incredible that he has remodeled all the rooms! This self sufficiency and talent reminds me of Tom, two men cut from the same cloth in many ways.
We toured their beautiful home and then visited Fort Gulf Beach in Crystal River. Just a short ride brought us to a sandy beach, many palm trees and the Gulf Of Mexico. Many families were enjoying the beach and water on such a nice day. We walked past the beach to a boardwalk immersed in tropical greenery and Spanish moss hanging from trees. Besides the glowing sunlight, the palm trees dotted here and there and the gray stringy Spanish moss introduced us to the south.
Standing on the dock, we looked over the never ending ocean, the Gulf of Mexico which is really part of the Atlantic Ocean. People fished from the dock as the four of us enjoyed the view and soaked up the sun. It definitely was a beautiful spot to walk, go fishing, swimming and sunning at the beach.
An afternoon of lounging in the pool ended with a lovely dinner of angel hair and breaded baked chicken. Mary's daughter, our niece, Joanne and her family came to visit. It had been years since we had seen them…it was so wonderful to see her and her family and visit. Her boys are good kids and growing so much! God bless them as they grow.
We feel so blessed to have such a great, magical stay for a couple of days. Many thanks to Mary and Joe for their hospitality and love!
My next few posts will focus on our Florida stay, from visiting Silver Springs State Park to Circle B Bar Reserve and our stay with his sister, Pam and our brother in law, Jim and his mom, Theo. 💕It was an amazing few days all around and now we all have wonderful memories of it! I hope you'll enjoy my posts and Tom's photos!
I live in the mountains up North and love them like close family. My heart also belongs at the beach. If I had to choose between the two, I couldn't!
I'm loyal to the steadfast mountains for they are my home. Believe it or not I never tire of their monstrous slopes and gray faces. It's peaceful and quiet, close to nature and God. This time of year snow frosts them and driving by close to Cannon Mountain miniature skiers sway to and from down the trails. The air is as fresh as you get and while hiking you can smell wafts of pine.
I don't remember the first time that I saw the ocean or smelled it's salty, fishy scent. I do know that once I left it, it's calm and soothing essence stayed in my soul. I can count on one hand how many times I visited the shore as a child and teenager but the frequency increased as I grew into a woman. Every time I walk along the sandy beach and feel the sizzling sun bake my skin and gaze at the horizon of blue and crest of white, I love it even more.
As every year passes, these places remain to be a part of me. How thankful I am to love where I live in the mountains and wake up every morning as if it's my first day here! My husband truly loves living here too but has grown to enjoy the ocean too.
Most of our vacations are to Ogunquit, Maine, about three and a half hours from here. It's a wonderful seaside town with outstanding restaurants, quaint little shops, and accommodations dotting here and there. We used to take the boys with nets, sand shovels and pails bouncing around in the back of our vehicle. Windows rolled down and laughter in the air, the mountains would slowly be replaced with a lower elevation and water as far as the eye can see.
I will never choose between the two…but continue to enjoy both places and love them both for different reasons. Isn't that the best way to really live?


text:
Test code: 04151
10–21 calendar days (14 days on average)
Preferred specimen:
3mL whole blood in a purple-top tube
Alternate specimens:
DNA or saliva/assisted saliva
Request a sample kit
New York Approved: YES
Invitae RASopathies Comprehensive Panel
Test description
The Invitae RASopathies Comprehensive Panel analyzes 18 genes that are members of the mitogen-activated protein kinase (Ras/MAPK) pathway, which is associated with a class of pediatric disorders termed "RASopathies" (also known as Noonan Spectrum Disorders). RASopathies are a class of pediatric disorders whose spectrum of symptoms include distinctive facial features, heart defects, developmental delay, and an increased risk of malignancies.
Proper management by specialists across a variety of disciplines is critical because it is essential that the different disorders be correctly identified and appropriately managed. The Invitae RASopathies Comprehensive panel provides a comprehensive approach to testing individuals who have features that fall within the RASopathies spectrum.
Genes tested
A2ML1 BRAF CBL HRAS KRAS MAP2K1 MAP2K2 NF1 NRAS PTPN11 RAF1 RASA1 RIT1 RRAS SHOC2 SOS1 SOS2 SPRED1
Primary panel (18 genes)
Customized gene selection (0 included, 0 excluded)
Panel details and technical assay limitations
Disorders tested
capillary malformation-arteriovenous malformation syndrome (CM-AVM)
cardio-facio-cutaneous syndrome (CFC)
Costello syndrome
neurofibromatosis type 1 (NF1)
Noonan syndrome with multiple lentigines (NSML) – formerly known as LEOPARD syndrome
Clinical description
RASopathies are a class of pediatric developmental disorders that share a common spectrum of symptoms, including congenital heart defects, short stature, distinctive craniofacial features, cutaneous abnormalities affecting the skin and hair, varying degrees of developmental delay, and development of tumors, both benign and cancerous. Additional information about each disorder is available by following the links below to their respective condition's page.
Main clinical features
Noonan syndrome Characteristic facial features, short stature, congenital heart defects (pulmonary valve stenosis), chest deformities, coagulation and lymphatic deficiencies
Noonan syndrome with multiple lentigines (formerly known as LEOPARD syndrome) Lentigines and café-au-lait macules, hearing loss, congenital heart defects (pulmonary valve stenosis), short stature, increased risk of malignancies
Cardio-facio-cutaneous syndrome Failure to thrive and feeding difficulties, congenital heart defects, characteristic facial features, curly sparse hair and skin rashes, neurologic complications (e.g., hypotonia, motor delay), developmental delay
Costello syndrome Coarse facial features, congenital heart defects, failure to thrive and feeding difficulties, developmental delay and intellectual disability, deep palmar and plantar creases, increased risk of malignancies
Legius syndrome Café-au-lait macules, axillary and inguinal freckling, macrocephaly, lipomas
Neurofibromatosis type 1 Café-au-lait macules, axillary and inguinal freckling, neurofibromas, short stature, macrocephaly
Capillary malformation-arteriovenous malformation syndrome Capillary malformations
The clinical sensitivity of this test is dependent on the patient's underlying genetic condition. For each condition, the chart below shows the percentage of clinical cases in which a pathogenic variant is expected to be identified through analysis of the genes on this panel.
NSML
Legius
CM-AVM
A2ML1 unknown
BRAF <2% rare 75%
CBL <1%
HRAS 80%-90%
KRAS <5% <2%
MAP2K1 <2% 10%-15%
MAP2K2 rare 10%-15%
NF1 ~95%
NRAS rare
PTPN11 50% 90%
RAF1 5%-10% 5%
RASA1 ~70%
RIT1 <2%
RRAS unknown
SHOC2 <1% unknown
SOS1 10%-15% unknown
SOS2 rare
SPRED1 >99%
All RASopathy conditions have an autosomal dominant inheritance pattern.
The RASopathies are highly penetrant conditions whose clinical expression is widely variable, even among family members.
Prevalence/Incidence
The RASopathies represent one of the largest groups of genetic syndromes, with incidences ranging from a few hundred cases worldwide to approximately 1 in 1,000 individuals.
Estimated prevalence for each syndrome is:
Noonan syndrome: 1 in 1000 to 1 in 2500
NF1: 1 in 3000
CFC: ~1 in 810,000 to 1 in 150,000
CM-AVM: ~1 in 100,000
Noonan syndrome with multiple lentigines (NSML), Costello syndrome, and Legius syndrome are reportedly rare and their prevalence is currently unknown.
Considerations for testing
This test may be considered for individuals with:
a clinical diagnosis or suspicion of any of the RASopathy disorders
a family history of a RASopathy disorder
features that are consistent with a RASopathy disorder and negative results from previous molecular testing of select genes
Clinical findings suggestive of RASopathies include short stature, congenital heart defects, developmental delay, broad or webbed neck, unusual chest shape with superior pectus carinatum and inferior pectus excavatum, cryptorchidism, characteristic facies, varied coagulation defects, lymphatic dysplasias, and ocular abnormalities.
Rauen, KA. The RASopathies. Annu Rev Genomics Hum Genet. 2013; 14:355-69. doi: 10.1146/annurev-genom-091212-153523. PMID: 23875798
Tidyman, WE, Rauen, KA. The RASopathies: developmental syndromes of Ras/MAPK pathway dysregulation. Curr. Opin. Genet. Dev. 2009; 19(3):230-6. doi: 10.1016/j.gde.2009.04.001. PMID: 19467855
Smpokou, P, et al. Malignancy in Noonan syndrome and related disorders. Clin. Genet. 2015; :None. doi: 10.1111/cge.12568. PMID: 25683281
Kratz, CP, et al. Cancer spectrum and frequency among children with Noonan, Costello, and cardio-facio-cutaneous syndromes. Br. J. Cancer. 2015; 112(8):1392-7. doi: 10.1038/bjc.2015.75. PMID: 25742478
Yamamoto, GL, et al. Rare variants in SOS2 and LZTR1 are associated with Noonan syndrome. J. Med. Genet. 2015; :None. PMID: 25795793
Cordeddu, V, et al. Activating Mutations Affecting the Dbl Homology Domain of SOS2 Cause Noonan Syndrome. Hum. Mutat. 2015; :None. PMID: 26173643
Aoki, Y, et al. Recent advances in RASopathies. J. Hum. Genet. 2016; 61(1):33-9. PMID: 26446362
Flex, E, et al. Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesis. Hum. Mol. Genet. 2014; 23(16):4315-27. PMID: 24705357
Digilio, MC, et al. RASopathies: Clinical Diagnosis in the First Year of Life. Mol Syndromol. 2011; 1(6):282-289. doi: 10.1159/000331266. PMID: 22190897
Niemeyer, CM. RAS diseases in children. Haematologica. 2014; 99(11):1653-62. doi: 10.3324/haematol.2014.114595. PMID: 25420281
Cizmarova, M, et al. Rasopathies - dysmorphic syndromes with short stature and risk of malignancy. Endocr Regul. 2013; 47(4):217-22. doi: 10.4149/endo_2013_04_217. PMID: 24156711
Rauen, KA, et al. Recent developments in neurofibromatoses and RASopathies: management, diagnosis and current and future therapeutic avenues. Am. J. Med. Genet. A. 2015; 167A(1):1-10. doi: 10.1002/ajmg.a.36793. PMID: 25393061
Allanson, JE, Roberts, AE. Noonan Syndrome. 2001 Nov 15. In: Pagon, RA, et al, editors. GeneReviews (Internet). University of Washington, Seattle; Available from: http://www.ncbi.nlm.nih.gov/books/NBK1124/ PMID: 20301303
Assay and technical information
Invitae is a College of American Pathologists (CAP)-accredited and Clinical Laboratory Improvement Amendments (CLIA)-certified clinical diagnostic laboratory performing full-gene sequencing and deletion/duplication analysis using next-generation sequencing technology (NGS).
Our sequence analysis covers clinically important regions of each gene, including coding exons, +/- 10 base pairs of adjacent intronic sequence in the transcript listed below. In addition, analysis covers the select non-coding variants specifically defined in the table below. Any variants that fall outside these regions are not analyzed. Any specific limitations in the analysis of these genes are also listed in the table below.
Based on validation study results, this assay achieves >99% analytical sensitivity and specificity for single nucleotide variants, insertions and deletions <15bp in length, and exon-level deletions and duplications. Invitae's methods also detect insertions and deletions larger than 15bp but smaller than a full exon but sensitivity for these may be marginally reduced. Invitae's deletion/duplication analysis determines copy number at a single exon resolution at virtually all targeted exons. However, in rare situations, single-exon copy number events may not be analyzed due to inherent sequence properties or isolated reduction in data quality. Certain types of variants, such as structural rearrangements (e.g. inversions, gene conversion events, translocations, etc.) or variants embedded in sequence with complex architecture (e.g. short tandem repeats or segmental duplications), may not be detected. Additionally, it may not be possible to fully resolve certain details about variants, such as mosaicism, phasing, or mapping ambiguity. Unless explicitly guaranteed, sequence changes in the promoter, non-coding exons, and other non-coding regions are not covered by this assay. Please consult the test definition on our website for details regarding regions or types of variants that are covered or excluded for this test. This report reflects the analysis of an extracted genomic DNA sample. In very rare cases, (circulating hematolymphoid neoplasm, bone marrow transplant, recent blood transfusion) the analyzed DNA may not represent the patient's constitutional genome.
Transcript reference
Sequencing analysis
Deletion/Duplication analysis
A2ML1 NM_144670.4
BRAF NM_004333.4
CBL NM_005188.3
HRAS NM_005343.2
KRAS NM_004985.4
MAP2K1 NM_002755.3
NF1 NM_000267.3
NRAS NM_002524.4
PTPN11 NM_002834.3
RAF1 NM_002880.3
RASA1 NM_002890.2
RIT1 NM_006912.5
RRAS NM_006270.4
SHOC2 NM_007373.3
SOS1 NM_005633.3
SPRED1 NM_152594.2
Cardiology gene list Cardiology management guidelines Invitae brochure Pediatric genetics gene list Why is cardiology genetic testing important?
Patient guide: Genetic testing simplified Patient guide: Hereditary heart conditions
Forms page Specimen requirements page
Headquarters | 458 Brannan Street, San Francisco, CA 94107
Laboratory & Shipping | 475 Brannan Street, Suite 230, San Francisco, CA 94107 | www.invitae.com
In the US | clientservices@invitae.com | p: 800-436-3037 | f: 415-276-4164
Outside the US | globalsupport@invitae.com or visit www.invitae.com/contact
©2015 Invitae Corp. All rights reserved.
Adding this test will result in an order that contains multiple clinical areas. If you choose to add this test, you will need to send in two sample tubes and your order will represent two billable events. Your test results will be delivered as two reports. Please contact Client Services with any questions.
Add this test to my order:
This test cannot be added as a re-requisition at no additional charge because it is in a different clinical area or was not available at the time of the original order.
If you would like to order this test, please submit a new order, which will require a new specimen and be billed as a separate test.
For more information, please visit our re-requisition page or contact Client Services with any questions.
Removing these genes will change this order to a re-requisition. Re-requisitions are offered at no additional charge and do not require an additional sample tube.
To add genes that are eligible for re-requisition, select from the Test Catalog or previously saved custom orders. These genes are shown in blue in the Test Catalog.
STAT turnaround tests cannot be combined with other test types. Exome slice tests cannot be combined with other test types. This panel cannot be combined with other test types. Carrier tests cannot be combined with other test types. Proactive tests cannot be combined with other test types. NIPS tests cannot be combined with other test types. If you wish to add this test you will need to clear your order.
Do you want to clear your order and add this test?
Yes add this test
No keep my current order
Editing your test selection will clear your reflex selection. Are you sure you want to proceed?
Additional genes required
At this time, you cannot order FMR1 as an individual gene, it must be ordered with another carrier gene. Please include at least one other gene with your FMR1 order.
Invitae does not offer diagnostic testing for fragile X syndrome at this time.
Fixed gene list
STAT panels are not customizable in order to support the accelerated turnaround time.
This panel is not customizable at this time.
The following genes are required for Invitae carrier screening and will be added to your order, CFTR (cystic fibrosis), SMN1 (spinal muscular atrophy), FMR1 (fragile X syndrome). Do you wish to proceed and add these tests to your cart?
Yes add tests
Please select only one of the proactive tests. If you would like to order our most comprehensive proactive test, we recommend the Invitae Genetic Health Screen.
Would you like to update your order to the Invitae Genetic Health Screen?
Yes add different test
Proactive tests are not customizable.


Answer: Hi dear plz don't worry. At 34 weeks you will need 2.1 kg and at the time of delivery, you will need an average weight of 2.5 kg. Have lots of leafy Vegetables, dry fruits, ragi, sweet potato, milk, eggs..all these will increase the baby's weight. Nothing to worry dear. There's still time. Your baby will gain weight and you will have normal delivery.
Answer: 2 kg is good as u hv some more days till ur delivery ur baby weight will increase don't worry just take nutritious diet.
Question: Hi, i am 34 weeks pregnant and baby weight is 2 pound. Doctor said weight of the baby is too less. How can i increase babies weight?