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The New Ford Mustang Keeps You Safely on the Road | Dean Arbour Ford of West Branch Inc.
Even the most cautious and attentive drivers occasionally fall victim to a lapse in focus or a simple mistake. Fortunately, advances in technology have allowed for safety features that could be as revolutionary as the seat belt and airbag were in their day. The 2018 Ford Mustang comes equipped with this latest in safety technology, so you can own one of the most popular sports cars of all time and be extremely safe driving it.
One of the most important safety features on the new Mustang is the Pre-Collision Assist and Pedestrian Detection System. It uses radar and cameras to detect when you are approaching another vehicle or object too quickly and begins applying the brakes before you even realize what is occurring. The Pedestrian Detection System will also warn you and brake if someone walks out in front of or behind your vehicle, keeping those around you safe as well.
Test driving the new Mustang at Dean Arbour Ford in West Branch, MI is the best way to learn about all of the amazing safety features, as well as the top of the line performance options, available on the car. Come in today to experience it first hand.


THE WORD OF TRUTH: Why Worry?
Why worry? Does it do any good? You may say, "I can't help it." I hope you don't believe that. The Bible teaches there is something you can do. "Don't worry about anything; instead, pray about everything. Tell God what you need, and thank him for all he has done" (Philippians 4:6, NLT).
Said the robin to the sparrow, "Why do these human beings run around and worry so?" Said the sparrow to the robin, "Surely it must be, they have no heavenly Father like you and me." Jesus taught that if God feeds the sparrow, surely He will take care of His children. You are more important to Him than a sparrow. Faith looks to God as a loving heavenly Father, and says, "I trust God to help me. He's my Father. I'm His child."
Pray the Word: Heavenly Father, I confess that I worry rather than pray about some things. You know my needs. I trust you for help. Thank you for all that you have done for me, through Jesus Christ. Amen.
Do the Word: Make a list of your worries. Now, go through them in prayer. Trust your Heavenly Father with every care, because he really does care for you. Put a date on your list. Go back at a later date and thank God for helping you.


What leaders of corporations and organizations say about others can play a powerful role in the culture that their company adopts. In addition to actions, policies, and communications, companies reflect what their leaders say. This can be revealing.
Take Donald Trump, for example.
From all appearances, Trump seems to run a successful organization. The success of his companies, just as is the case with ANY company, has as much to do with the character of its leaders as its strategy. This character, referred to as its culture, is much more powerful than its strategy. It defines who the company is.
When a leader uses phrases to describe other people including "fat", "slob", and "ugly", it makes a strong statement to the employees of the company. This statement comes in two flavors.
One is the statement that is made to leaders of the company. In most cases, leaders of any group tend to emulate THE single leader. Leaders want to be included in the plans of the key person and will tend to follow that person's culture via their actions and words. In other words, they want to impress that key leader and what better way is there than to be like them? If the leader likes his or her self, they will certainly like others who are similar to them... right?
So it becomes easy to emulate that leader by talking like them. If it's okay for the leader to use these phrases, it must be okay for his followers to use them.
The leaders who don't feel comfortable in this culture will find a way to separate themselves from this talk, often leaving the company. They will be replaced by others who "fit in" with this kind of attitude.
This leads to the second statement, which is made indirectly to the employees, especially employees who sense that they fit into the categories being described unflatteringly by the leaders.
These same employees, many of whom are probably of high value to their organization, hear these comments which come from their leaders and begin to feel that THEY don't fit in the culture which the leaders are describing verbally. As they sense this lack of inclusion, they will similarly feel their lack of fitting in and separate themselves from others, again often leaving the company.
Can casual comments actually lead to such cultural changes? You bet. Take a close look at the adoration of employees of a charismatic leader such as Donald Trump. They watch every move, every comment, very closely, especially those with desire for upward mobility. They want to impress this leader, be "like him". Others within the organization want to be liked by their leaders.
Carefully study the heads of companies that you do business with or that you observe. Listen to the words of these individuals, watch their actions. You'll see that same attitude throughout the organization, from top to bottom. They will attract employees and managers with similar beliefs.
And if you like working for a name-calling, tough-talking company, I've got a suggestion for you.


text:
Q: Using transistors (or relays) on a 12V 3A pump I am trying to use an Arduino Uno to separately control a 12V .5A solenoid, a 12V 1.5A solenoid, and a 12V 3A pump. I am currently using a TIP120 NPN transistor for each one controlled by the 5V output of the Arduino, but the pump transistor is getting hot after only about 30 seconds of runtime.
To reduce the heat, should I put two transistors in parallel and have a limiting resistor after to limit the current flow? As of now the pump is not pumping hard enough and I would like to get more current (?) to make it run harder. I know it can run harder if it gets the required energy. My power supply says that I am only drawing 2.6 A total for all three, (2 solenoids and a pump/motor) which are hooked up in parallel to the 12V supply and it seems to just max out at that, although at 12V, it says on the power supply it can supply 6A.
The solenoid transistors seem to be fine, the only issue I am having is with the pump transistor getting hot and not delivering enough current to make the pump go hard enough.
Questions

*

*Does the current or the voltage drive the motor? Or both?

*Would only having 1.5A flow through each transistor to get 3A to the motor be too much current?

*Do I need to put a resistor in line with the Arduino signal voltage? (Beta (DC voltage gain) for TIP120 is 1000 on datasheet)

*Should I get a bigger transistor? A MOSFET? Which one?

*Should I get a relay instead? Which one?

A: The reason your transistor is heating too much is because it's a darlington and has a volt or more drop at 3A. The TO-220 package is good for 1 to 1.5 watt without a heatsink; you have at least double that.
Since the supply voltage is only 12V, I suggest using a MOSFET. For example, the IRLZ34 is rated 60V, with 50 milliohm Rds at 5V gate-to-source.  A 100 ohm resistor in series with the gate should calm the the switching and 10k from gate to source makes sure it's off when not powered.  A 3A-rated diode around the motor (cathode to positive) is good insurance that any inductive spike on turn-off is not absorbed by the MOSFET.
The other questions:
On a DC motor, voltage determines the motor speed, the motor draws as much current as is needed to run its load at that speed. Voltage drop across the transistor (and wiring) will reduce motor speed.
It would be a good idea to have resistors in series with the outputs to limit the base current. You probably only need 10mA or less, so like 390 ohms.
I wouldn't use a relay, since you don't need isolation. A MOSFET is probably less expensive than a relay, and the relay might need its own drive circuit if your output is inadequate.

A:
Here is the layout for the pump if I do use two transistors.

A:
Here is overall setup. The only part that really matters is the right hand side. I just have it shown here as a single transistor, but I could use two transistors or use a relay, or really just whatever you all think would work well.
]2

redpajama_set_name: RedPajamaStackExchange


text:
December, 21st
5 mental health tips as we wait for the pandemic to end – Tampa Bay Times
After a long, isolating year, hope is in sight with vaccines arriving in Florida hospitals and nursing homes. But as exciting as the idea of pandemic-free life sounds, the end could still be months away.
"Anytime that you have something as big as this pandemic has been, and you start to hear that there might be a light at the end of the tunnel, people are going to anticipate that," said Dr. Ryan Wagoner, vice chairman for clinical services at USF Health Psychiatry and Behavior Neurosciences. "There's that surge of, 'This is finally going to be over.'"
Wagoner says it's normal if you feel a bit of a slump after the initial excitement of seeing vaccines roll out. He compares it to waiting for an online shopping order and then finding out the package has been delayed.
"You're still excited about it coming in," he said. "But there's obviously that sense of letdown in that you still have to wait for it. And so of course, people are going to get stressed and feel anxious about that."
As we anticipate improvements in 2021, here are some tips for getting through vaccine limbo.
Set short term goals and rewards
Experts estimate that the coronavirus vaccines won't be widely available until at least March or April. Surveys show that a number of health care employees are wary of the quickly-developed shots, and many people may wait even longer to get their immunizations.
Related: Tampa Bay health workers first to get coronavirus vaccine, but many say they'll pass
"It's all well and good to look forward to early spring when the vaccine might be widespread," Wagoner said. "However, it's also really important to focus on things that you can accomplish in little bites."
Instead of fixating on how long things are taking, immerse yourself in achieving small goals. Focus on finishing a home improvement project. Don't forget to set a reward, such as treating yourself to takeout.
Practice moderation with social media and news
There's more encouraging news about medical advances than during earlier points in the pandemic, from the vaccine rollouts to the FDA approving at-home coronavirus tests. That good news comes mixed with reports of rising coronavirus cases and deaths. Even seeing posts from friends getting the vaccine can have a negative effect, Wagoner said.
"It's helpful because it gets out there that the vaccine is safe, people are getting it," he said. "But on the other hand, people who may not receive it for weeks to months from now, that may make them feel worse."
Related: Coronavirus anxiety is real. Here are mental health tips to help.
You don't have to quit Twitter cold turkey. Instead, set aside specific times to scroll (a morning check-in, during lunch, and once more in the evening). This gives you something to look forward to without overloading.
"If you need to be informed, great, but don't let it consume you," he said. "Because I do see that happened with folks, especially when they're isolating, especially when they're feeling stressed."
Look forward to regaining consistency, not "returning back to normal."
Pandemic routines like mask wearing, social distancing and avoiding large gatherings won't be with us forever. But fantasizing about getting back to how things used to be may set up an unrealistic expectation, Wagoner said. What most people crave is not going back in time, but getting consistency back into their life.
"We're different people every single day, and so are we going to return to exactly like we were before all of this hit? Of course not," he said. "There have been many things that have changed, some actually for the better."
Wagoner recommends thinking about how to implement new things we've picked up in this pandemic lifestyle rather than trying to get back to how things used to be.
Related: Feeling holiday stress? Queer Eye's Karamo Brown has tips to help you cope.
Don't feel bad for saying no
You may have trouble convincing your family to hold off on hosting large gatherings or telling your friends to avoid crowded bars and indoor restaurants. If talking doesn't help, you may have to remove yourself in that situation, which could end in hurt feelings.
"The biggest thing that I've found helpful is to emphasize what you yourself are comfortable with, and that that has nothing to do with the other people," Wagoner said. "So it's not that you don't want to visit with your parents. It's not that you don't want to see your cousins."
If you choose to stay away from friends and loved ones for health reasons, find ways to still spend time together from a distance. Call someone you haven't spoken to in months. FaceTime your coworkers. Even try writing handwritten letters.
"Physical isolation does not equal social isolation," he said. "You can still maintain contact even if you're not in the same place."
The idea of planning a getaway or buying tickets for an event in spring 2021 may be tempting. Wagoner said this isn't a bad idea — but only if you don't mind going with the flow.
"If you're a person that finds that anytime a plan changes that upsets you or stresses you out, I probably wouldn't recommend doing something like planning vacations in the summer, because there's still a lot of unknowns," he said.
Get help if you need it
Pay attention to your feelings and reach out if needed. Feeling some sadness and anxiety is normal, but if your appetite, sleep or energy levels are affected, get help.
To find a mental health professional, visit the National Alliance on Mental Illness website.
Additionally, the following 24/7 crisis hotlines provide free, confidential emotional support:
Author: Healthy Life Diet
7-day healthy eating meal plans for men and women proven by science – Medical News Today
The Worst Weight Loss Tip of 2020, According to a RD | Eat This Not That – Eat This, Not That
If so, please join 1000+ people who receive weekly health tips!
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Provides a search function to find avaliable mental health support services within your local area.
Provides videos, podcasts and other resources to help people look after their own mental health.
Brings together four national mental health charities working across the UK.
Mental health charity providing information and support on various mental health problems including anxiety, self-esteem and common eating disorders.
A registered charity which helps people who suffer from panic attacks, phobias, obsessive compulsive disorders and other related anxiety disorders.
A series of self-help leaflets covering a range of issues including sleep problems, stress, controlling anger and alcohol use.
A charity offering advice and information to anyone affected by mental health problems.
An independent professional membership organisation and registered charity which provides a range of information and resources for mental health professionals and the public.
Information, resources and helpline providing emotional support and information to anyone affected by mental illness, including families, friends and carers.
Offers information and resources validated by health professionals alongside tips and advice from students who have experienced low mood or depression themselves.
Student mental health charity, offering information and resources on a variety of topics, including managing exam stress, preparing for a year abroad and supporting a friend.
Support service for people aged under 25, offering free and confidential support and advice on a wide range of issues including mental health, money worries and relationship break ups.
BACP is a professional body and a registered charity which provides information about counselling and psychotherapy, including how to find a private therapist.
Provides self-help and therapy resources, including worksheets and information sheets and self-help mp3s.
A self-help site addressing a wide variety of problem areas, including: depression, social anxiety, panic, worry, self-esteem, procrastination, assertiveness, and eating problems.
Offers a range of self-help methods for people who want to learn about managing their anxiety.
A simple tool which uses mindfulness meditation to help combat stress, improve focus and increase resilience.
For young people who have already started the process of understanding their self-harm issues. Provides tasks to resist or manage the urge to self-harm.
Includes advice, tips and tools to improve mental health and boost wellbeing.
Regular animated show which explores the physical, mental and emotional paths to wellness.
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After spending a few days in the 100+ degree, dry heat of Las Vegas, I've had some time to cool off and reflect on the action-packed digital event.
First off, I was pleased that our very own Aaron Schinke and Eric Giroux had the opportunity to kick off the conference with a 9 a.m. workshop on Monday. Their insights into digital retailing, specifically digital marketing, seemed to be very well received. If you missed "The Down and Dirty of Digital Retail," don't worry; they will be presenting this topic again at our upcoming customer conference in October.
This Digital Dealer felt like it had a bit of a different vibe than in previous years. Perhaps it was because it was August rather than October or maybe because it was at the MGM Grand instead of the Mirage. I was curious about attendance, and after asking around, I heard that about 1,250 dealers attended, not including vendors. Based on casual conversation I overheard at the booth and through (accidental) eavesdropping, it seemed that dealers in attendance were looking for new technology.
DealerSocket saw a steady stream of visitors throughout the event. Our booth was packed even before the expo hall officially opened Monday morning. Dealers were anxious to talk to vendors early on so that they could analyze and compare all the different offerings before making a final decision. And yes, the Be Back bus rolled on through Tuesday and Wednesday morning.
It was clear that digital retail was all the buzz. Many breakout sessions covered digital retail or digital storefront specifically, with each presenter sharing interesting theories and approaches. I'm not certain, though, the message resonated with dealers. And, spoiler alert: Our bet for the next trending topic in 2017 is telematics in fixed operations.
Overall, Team DealerSocket nailed another expo. We rocked our special edition Team USA "We Are Automotive" tees — our Canadian rep too. We streamed Olympic coverage and witnessed the USA dominate women's artistic gymnastics. We had fun chewing the fat with customers and talking everything CRM, inventory management, and websites.
I enjoyed meeting a lot of new people: dealers, vendors, and team members. I can't wait for the next major industry event, which just so happens to be our very own DealerSocket User Summit taking place October 3–5 in San Antonio, Texas. Hope to see "y'all" there!


"Sergey Shutov. EVERYTHING HAS ALREADY BEEN STOLEN" // December, 01, 2014.
In december 03-24 we're glad to invite you to look at the new project by Sergey Shutov EVERYTHING HAS ALREADY BEEN STOLEN (paintings).
"Vladimir Sitnikov. THE FATEFUL EGGS / painting /" // November, 11, 2014.
"Vladimir Semensky. TERMINAL / paintings /" // October, 13, 2014.
Opening reception - may 1st at 6 p.m. Exhibition is held till the 9-th of November, don't miss!
"Krokin gallery at Instagram" // October, 01, 2014.
"ZOO project. EXPOSITION PHOTOS" // October, 01, 2014.
Exposition photos of the group project ZOO in Moscow Zoological museum of Moscow State University.
"Andrey Bilzho. CLASSICS OF PAINTING" // September, 29, 2014.
Till October, 12 only. Don't miss!:) The project by well-known Andrey Bilzho CLASSICS OF PAINTING (painting).
Exhibition address: Moscow, Kozitskiy bystreet 5.You're welcome!
"ZOO /group project with Zoological museum of Moscow State University/" // September, 13, 2014.
"Alexander Djikia. ZOOGRAPHY" // September, 03, 2014.
We're glad to invite you to look at new project of Alexander Djikia ZOOGRAPHY (graphics).
"Sergey Tsigal. CRIMEA / paintings /" // August, 18, 2014.
In August, 20 - September, 01 we're glad to invite you to exhibition of paintings by Sergey Tsigal The CRIMEA. Opening reception - august 20 at 6 p.m.
"K.Batynkov project is prolonged till 16.08" // July, 22, 2014.
"Konstantin Batynkov. VIEW OUT OF THE WINDOW" // June, 20, 2014.
We're glad to invite you to look at new solo project by Konstantin Batynkov VIEW OUT OF THE WINDOW (paintings).
"Boris Kocheishvili. LIGHT GRAPHICS" // June, 03, 2014.
In June 04-22 we're glad to invite you to look at the project by Boris Kocheishvili LIGHT GRAPHICS.
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Opening reception - may 1st at 6 p.m. Exhibition is held till the 1st of June, don't miss!
"Francisco Infante & Nonna Goriounova. RE-CONSTRUCTIONS" // March, 25, 2014.
We're glad to invite you to look at the project by well-know artists Francisco Infante and Nonna Goriounova RE-CONSTRUCTIONS (artefacts of 1977 - 2013).
"Alexey Politov & Marina Belova. CROCKS / graphics /" // February, 21, 2014.
In February, 27 - March, 23 we're performing the project by Alexey Politov & Marina Belova CROCKS (graphics), inspired by works of A.P. Timofeevsky. Opening reception - february 27 at 6 p.m.
"Vasily Smirnov. READING-BOOK / paintings /" // January, 29, 2014.
We're glad to invite you to look at new solo project by Vasily Smirnov READING-BOOK (paintings).


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Balancing easier access and greater security of healthcare data
Security is a big topic for healthcare right now and has been for some years. Johan Sörmling, Managing Director at Encap Security and Head of Mobile Identity at Signicat, believes that healthcare has a great deal to learn from other markets—in particular fintech. He believes it's important to think of app users, no matter the app, as consumers when considering how to attract and keep people using healthcare apps.
We knew that access to healthcare data was valuable, but the last eighteen months has made it clear just how vital access to data is. Governments have used data to make decisions on border control and lockdowns. Healthcare authorities have used data to prioritise vaccination programs and resources. People have been able to use published data to better understand the scale of the pandemic and make decisions on the level of risk that they feel comfortable with.
One big lesson of the pandemic has been that sharing health data is good for decision making.
Unfortunately, it's also been a bad time for data security. One report suggests that the industry has experienced a 51% increase in the total number of records exposed, from 2019 to 2020. Healthcare has also become a big target for ransomware, with Ireland falling victim to a "catastrophic" attack in May 2021, and Germany being attacked in late 2020. The Vastaamo hack was possibly the most damaging of all, with a security flaw in exposing its entire patient database, including email addresses and social security numbers, but the actual written notes that therapists had taken.
Healthcare data can be some of the most sensitive information that's held about us, ranging from the mundane to the intensely private. The lesson that some of the public may take away from the last few years is that sharing data is risky, and could mean a loss of control.
If healthcare providers want their patients to install and use the apps they have created, they may need to look to the success of other sectors to better understand how they can get people on board.
Healthcare apps as consumer apps
European regulators are keen to make mobile health a reality across the continent and have been for the best part of a decade, creating regulations and legal frameworks, and funding projects through its Horizon 2020 program.
Digital health and mhealth adoption has been patchy. As an example, France has been breaking records for telemedicine and has started trials for a vaccine passport. A new healthcare act adopted in 2019 is looking to expand the country's focus on digital health—improving interoperability, establishing a data hub and make use of artificial intelligence. Germany has also been doing similarly good work since a change in health minister in 2019 meant a new way of doing things.
Elsewhere, progress has been slower. The app designed to help monitor the spread of COVID-19 has been described as a "fiasco", while a study from the British Medical Journal found that many mhealth apps lacked privacy controls. One report claims that 71% of healthcare apps have a serious vulnerability.
Even as people choose to engage with healthcare apps, there are going to be problems—not every app will be of the same quality, and the public's perception may be affected by poor-quality apps. This is a problem in every sector. Maybe it's time to learn from them?
Financial services, for example, is another sector where people have data they want to keep to themselves, and only they should have access. In recent years, there's been a huge shift to mobile apps. One in five UK customers, for example, now use challenger banks—huge if you consider how young the fintech sector is compared to the incumbent financial sector.
For healthcare apps to do the same, maybe it's time to think more like a fintech?
Learning lessons from elsewhere
What is the secret to fintech success? It's a focus on customer experience. No one should find an app difficult to use or find it confusing. If they do, they will quickly abandon the app for one that's more welcoming, and there are many alternatives on the market.
This attention to the customer experience includes one of the most important parts of any app, authentication. It's also the part where many businesses go wrong. Authentication tells a business that the customer returning to their app is who they say they are. Often this is done with a username and password, but this is notoriously insecure—many people reuse passwords or use passwords that are simple and easily guessed. But additional security can mean making things more difficult for the customer—and turning them away from the app due to a poor experience.
Consumers need to both be protected, and feel protected. Security needs to be just a little bit visible so that they know it is there and they feel safe. If it's completely invisible, or in the way consumers will walk away. So how can mhealth apps solve this problem?
If mhealth apps want customers to both be secure and feel secure in their apps, they need to start using some of the techniques that have been proven elsewhere. They need to use two-factor authentication. Consumers increasingly expect this level of protection, and many are now demanding it. If you have entered a code sent to you by text, then you have used two-factor authentication, but this is not the best way to do it. SMS text messages are not secure—anyone can send them, and they can be used in what's called a "man in the middle" attack to take over an account.
Luckily, there's a solution thanks to where the app exists in the first place. Smartphones are smarter than ever, with face and fingerprint recognition common. Integrating these makes two factor authentication easy for the consumer. Plus the data that the smartphone has access to, such as location, means that there can be far more confidence that the person using the app is who they say they are.
Healthcare AI startup Agamon raises $3m to automate hospitals' processes by transforming clinical text into data
Healthcare digitisation is seriously lagging
How healthcare CIOs can more easily innovate through interoperability
AI in Healthcare: Applying the Automation Spectrum to Business
Any app that wants to be successful needs to look beyond its own sector for best practice. For consumers, their banking app, games and mhealth all exist on the same device, one tap away. We believe that mhealth apps cannot rely on their usefulness alone if they want customers to return to them—they will expect any app to achieve the same level of accessibility no matter if it's offering pure entertainment or advice for good health. mhealth apps are not competing with other mhealth apps, but with every other app on a customer's device.
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Amber Donovan-Stevens
Amber is a Content Editor at Top Business Tech


Thank you Linda for trusting me with your hip replacement surgery!
Linda L. He did bi lateral hip replacements for me !! I went from a wheelchair to walking with zero pain!! He is amazing!! He did my friends knees and she is doing fantastic!!! I woke up from my 1 st surgery in zero pain.. 5 weeks later I had my 2nd surgery… blew right through with out pain!! He is amazing!!


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Q: #MathdotNet How to find the parameters of Herschel-Bulkley model through Nonlinear Regression in Math.NET? First, I would like to thank everyone involved in this magnificent project, Math.NET saved my life!
I have few questions about the linear and nonlinear regression, I am a civil engineer and when I was working on my Master's degree, I needed to develop a C# application that calculates the Rheological parameters of concrete based on data acquired from a test.
One of the models that describes the rheological behavior of concrete is the "Herschel-Bulkley model" and it has this formula :
y = T + K*x^n
x (the shear-rate), y (shear-stress) are the values obtained from the test, while T,K and N are the parameters I need to determine.
I know that the value of "T" is between 0 and Ymin (Ymin is the smallest data point from the test), so here is what I did:
Since it is nonlinear equation, I had to make it linear, like this :
ln(y-T) = ln(K) + n*ln(x)
creat an array of possible values of T, from 0 to Ymin, and try each value in the equation,
then through linear regression I find the values of K and N,
then calculate the SSD, and store the results in an array,
after I finish all the possible values of T, I see which one had the smallest SSD, and use it to find the optimal K and N .
This method works, but I feel it is not as smart or elegant as it should be, there must be a better way to do it, and I was hoping to find it here, it is also very slow.
here is the code that I used:
    public static double HerschelBulkley(double shearRate, double tau0, double k, double n)
{
    var t = tau0 + k * Math.Pow(shearRate, n);
    return t;
}

public static (double Tau0, double K, double N, double DeltaMin, double RSquared) HerschelBulkleyModel(double[] shear, double[] shearRate, double step = 1000.0)
{
    // Calculate the number values from 0.0 to Shear.Min;
    var sm = (int) Math.Floor(shear.Min() * step);
    // Populate the Array of Tau0 with the values from 0 to sm
    var tau0Array = Enumerable.Range(0, sm).Select(t => t / step).ToArray();
    var kArray = new double[sm];
    var nArray = new double[sm];
    var deltaArray = new double[sm];
    var rSquaredArray = new double[sm];
    var shearRateLn = shearRate.Select(s => Math.Log(s)).ToArray();
    for (var i = 0; i < sm; i++)
    {
        var shearLn = shear.Select(s => Math.Log(s - tau0Array[i])).ToArray();
        var param = Fit.Line(shearRateLn, shearLn);
        kArray[i] = Math.Exp(param.Item1);
        nArray[i] = param.Item2;
        var shearHerschel = shearRate.Select(sr => HerschelBulkley(sr, tau0Array[i], kArray[i], nArray[i])).ToArray();
        deltaArray[i] = Distance.SSD(shearHerschel, shear);
        rSquaredArray[i] = GoodnessOfFit.RSquared(shearHerschel, shear);
    }
    var deltaMin = deltaArray.Min();
    var index = Array.IndexOf(deltaArray, deltaMin);
    var tau0 = tau0Array[index];
    var k = kArray[index];
    var n = nArray[index];
    var rSquared = rSquaredArray[index];
    return (tau0, k, n, deltaMin, rSquared);
}


Location: Lengkok Angsana, Bandar Baru, Farlim, Ayer Itam, 11500 Penang. Nearby Farlim Government Clinic, Farlim Market, Old Town white coffee, commercial shops and office, Pasar Malam, Schools...Just a stone throw away from Farlim Wet Market and Business Centre.
Facilities: 24 Hours Security with touch N & Go entrance, Multilevel covered carpark, skating ring, basketball court, outdoor gym, multipurpose court, children playground, carwash bay and community hall..


Could the experts in the forum talk a bit about game code architecture which should be followed for an optimized game? I am interested to know about design patterns.
- Let me be a bit more specific, how are popups introduced in game architecture ?
- Texts added in a file then depending on certain conditions, popup framework is called with specific text pulled from a file?
- or have different lua files for each overlay popup?
- I know it is kind of a vague question, but I would like to learn about optimized way, optimized architecture so that the coding can be done more efficiently.
This is how my apps are structured. I have a set of what I call domain objects. But they are just tables and properties in a file. A player and all the properties for example.
Then I have other sets of objects that do work and yet other objects I call factories but you guessed it they are just methods in table. So based on the config these tables are created and then domain objects are passed in to do work.
A concrete example: At start up the app looks at the config and sees that we are using Vungle and Admob. Calls the adFactory with the two keys Admob and Vungle. The factory uses those two keys to load to files based on the path in the config for those keys. Calls the init method for those two files and stuffs them in an array. The factory also attaches the callback of those two files to itself.
Now at some point we need an ad. We call the controller and tell it to show an ad of type x. The manager iterates through the collection and calls the show method of every file.
I use this pattern for everything or almost everything. The domain objects are passed in when required. Even the UI is built this way. I call the controller to build the navigation bar. It looks at the configuration loads a file based on a path and calls known methods for that factory. When a person clicks on a button. I send the button tag to the nav manager.
This is why most of my apps look sort of the same and why usually one update targets multiple apps.
So Back to your question. A manager needs a pop-up. Maybe it got an event that the level is over. Looks at the config when I get event x fire event y. In this case the event is showGoodJobOverlay. The overlay manager listens to that event pulls the config calls the factory with the property and then calls the show method.
If our pop-up has a button again fire an events a manager somewhere will be listening will create something in a factory or call one or more methods in a collections.
Most of my apps have either 1 or 2 scenes. When you click on the UI element I am just destroying and creating items. Even the managers are created this way. I can switch the config of a few users to try overlayManager2. At startup instead of the managerFactory creating v1 it would create v2. Hope this helps I can give you details if interested other people probably have better way to do this.
Sorry for the formating. Sadly in a hospital bed today with only my phone.
This is a great set of questions, but I suspect that even though you've listed specific questions, they may be still too broad to answer in the forums.
As for popup's there are generally two types: native dialog boxes and scene overlays. I would think most people would, for stylistic purposes use an overlay. Generically speaking they are just a display.newGroup() or display.newContainer() that contains the various display objects needed to show the overlay. If you're using Composer, it supports overlay scenes, so if you're comfortable working with Composer, then you might go that way.
For the second question on texts in a single module or different lua files, you need to learn DRY: Don't Repeat Yourself. Don't write the same code over and over. It's almost always better to use conditional tests and a singular set of code for this. This is also a practical example of the MVC pattern (Model View Controller).
With MVC, your model is your data. The View displays your data. Neither should know or care about the other. That is later you may want to change how the data displays, but you don't want to re-engineer your data. Your data should track the information that it needs to track and not be designed around how the data will be displayed. The Controller is the bridge that reads the data and communicates that data to the view.
For the last question, perhaps you should look at the sample projects from Ponywolf, like Endless Skateborder (You can find them in the Marketplace or on the Getting Started Guide) and study how they are organized and laid out.
I am sorry to hear you are in hospital bed, I hope it is nothing serious. Do not worry about the formatting, it looks better than my initial post. Thanks a billion for a very thorough post, loved the feedback, will try to implement on my own game.
Thank you @Rob for the response. I did realize after I posted that this is a broad topic of disucssion and cannot be covered in one thread. I will study examples you mentioned. I am happy to be part of such a vibrant forum.
Rob's "Don't repeat yourself" is a great piece of advice, and you should take it beyond individual projects.
Consider scenes like level select, options, in-app currency store or credits.
What's the one thing that they all have in common? People don't really care about any of them. Often not even the developers!
Level select is only a means of getting to the actual game and so it needs to be as smooth and as effortless as possible for the player, so that it doesn't annoy them. If a player goes to the options or credits scene, they'll probably do so only once or perhaps they are just lost, etc.
The point in all of this is that you should reuse as much code as you can.
For instance, we at Spyric have several custom scenes and overlays scenes that we just copy from one project to another. One such overlay scene is our "store.lua" file. The overlay scene itself doesn't contain any hardcoded values, but it gets its information from two associated files: translations.lua and settings.lua. The first file simply contains the strings for all text, buttons, etc. and the second file contains all display object specifications, such as how many buttons, what graphics do they use, where they are, their functions and id's, etc. The scene also contains special functions like watching ads to get currency or checking time from our server to get a daily reward.
When we started, we used to create the iap and store systems from the ground up for every project, which always took a few days and some more to squash all the bugs and test everything as well as set up all integration, etc. but these days we just copy this file from one project to another, change a few lines of code in the settings.lua file and call a custom scene. To be completely honest, the reason why programming these IAPs/stores always took us to long is because no one wanted to do them as they were so boring. So, now we can just cut a few days of boring work and possible bugs by calling just calling a scene that we know works.
Since we've got similar modules/scenes for options, credits, some types of level selects, etc. we are able to cut down a lot of development time and keep everyone working on more interesting tasks that actually matter.


Deputy Orange County Executive James D. O'Donnell has announced the County of Orange and the American Red Cross are opening a shelter at Taft Elementary School in Washingtonville at noon.
The shelter will operate for 24 hours until further notice.
Pets will be permitted at the shelter only to accommodate specific conditions, but they must be caged and the owner will be responsible for the health and safety of all pets.
Residents in need of assistance should contact 2-1-1 for additional information on opening of the shelter.


Collage created from diffusion imaging scans, sandblasted on front of mirror, hand painted.
34.5" x 24" x 1.5"
Glass stamps oil Transfer Painting on the right side of the mirror.
16.25" x 22.75" x 1.25"
Collage created from diffusion imaging scans, sandblasted on front of mirror.
34.5" x 20.875" x 1.5"
Collage created from diffusion imaging scans sandblasted onto the back side of the mirror, hand painted.
29.25" x 32.625" x 1.5"
Collage created from diffusion imaging scans sandblasted into the back side of the mirror left side, hand painted.
35" x 26" x 1.5"
35.5" x 28" x 1.5"
Collage created from diffusion imaging scans sandblasted into the face of the mirror left side, hand painted.
35.625" x 67.25" x 2.25"


Accueil Blog The next edition of the Paris Healthcare Week will be held from 29 to 31 May 2018.
New: Trade show open until 8 pm on Wednesday 30 May.
* Salon Infirmier, a unique trade show aimed at all nurses, who play an essential role in the provision of care.
"The Paris Healthcare Week is the largest professional event in the French healthcare sector. It is an annual event for stakeholders contributing to the modernisation of healthcare systems, and is an ideal place for professionals to talk about what they do and share their expertise, and to discuss current issues in the sector", explains Aube Jeanbart, Managing Director of the trade show.
The Paris Healthcare Week is an unmissable annual event for healthcare professionals. The trade show comprises an exhibition area and a space for discussions (conferences, themed villages and forums) for all stakeholders contributing to the modernisation of the way in which the healthcare system is organised, and serves as a veritable think tank thanks to the involvement of top-level experts.


The Le Sigh: 7": SALES - "Renee" / "Tonka Time"
7": SALES - "Renee" / "Tonka Time"
SALES' 7": two songs of synthy-pop wonderfulness.
I don't think my love of music needs any sort of justification, but just in case you didn't already know: I think music is the best thing about living. I play it when I'm in my car, getting ready for work, and just about any time I can possibly can. My favorite way to listen to music (yes, I have one of those) is to lie in bed, in complete darkness, and put on an album I'm in the mood for. I close my eyes and let my ears substitute for vision. When I first listened to SALES' new 7" "Renee" / "Tonka Time", I knew those songs were definitely lie-in-the-dark-worthy.
The split's first song, "Renee," begins with a catchy little guitar riff. Singer Lauren Morgan coos over the riff with an abstract melody. It's a song you can sing along to, but it isn't laced with major chords, as a typical sugary-sweet melody would. Morgan's voice is sweet but distinctive and the words they have written flow out of her throat perfectly. Just when you think "Renee" is going to be a pleasant, acoustic pop song, guitarist and producer Jordan Shih sneaks up from behind and adds a mellow beat that really flows well with the simplicity of the song. "Tonka Time", has a slow build, from quiet to powerful, and this has to do with their specific keyboards and programming. SALES manages to work in another lovely guitar riff in this song too; it seems to be their specialty. It's obvious that Morgan and Shih work well together as musicians. They both know exactly what kind of music they want to make and it shows in these wonderfully crafted songs. If you want to listen to SALES in the dark, or wherever it is you listen to music, you can buy their new 7".
renee / tonka time 7" by SALES Listen to SALES on bandcamp.


This listing is courtesy of Krikor Partamian from Johnhart Real Estate.
Country style living at its finest! Welcome to 48881 190th Street W located in Lancaster! Nestled on an almost 10-acre land resides a charming fenced with chain-linked home with a 12X16 front porch, a 30X60 work shop, 30X100 Green house growing tilapia fishes and a 12x12 freezer storage! The home with an alarm system offers 3 bedrooms with 3 bathrooms and 2,128sqft of living space! Inside find an open floor-plan with electric Central A/C and Heating, laminate flooring, baseboard moldings and a large well-crafted fireplace in the living room. Tile counter-tops in the kitchen with wooden cabinetry and a breakfast bar for stool seating. Bedrooms are well-illuminated, spacious and features ample closet/storage space! This home also features a water is well and has 10,000-gallon water tank, electricity single phase and 3 phase 220 volt, a power plant 35 KW backup, plus propane gas! All 10 acres of land is setup for sprinkler system and has about 90 pomegranate trees!! With so much too offer you may never want to leave to home!


text:
Hospital politics refers to the informal interpersonal relationships medical staff create in the organization to enhance their status and fulfilling personal interests. By definition, this doesn't sound harmful, however, politics becomes a threat to unity when medical staff use it to slander colleagues or get them fired. That's why it's necessary to figure out how to avoid toxic hospital politics.
Who Are The Perpetrators Of Toxic Hospital Politics?
Staff Members That Are Experiencing Career Stagnation
Career stagnation causes an individual to feel resentment towards colleagues, especially newly hired staff. This negativity stems from the fear of getting replaced because the individual feels entitled to the position they've held for several years. Such people will use their relationships with their employers to frustrate the career growth of perceived threats.
Colleagues or Managers That Are Bitter Over Rejected Sexual/Romantic Advances
Female nurses can sometimes find themselves receiving an unusual level of attention from colleagues, supervisors, or managers heading various departments. Healthcare providers who adhere to high moral standards will reject dates and other forms of romantic advances. If the rejected individual has a high sense of self-entitlement, he might spread malicious rumors about the female nurse to humiliate her.
Retaliation For Reporting Substance Abuse
A coworker who finds out that a particular colleague reported their chemical impairment to the supervisor will hold a grudge and feel an urge to revenge. They can resort to drawing the hospital management's attention to make sure that their perceived enemy gets fired by spreading lies.
Insecure Nurse Supervisors
Sometimes, an RN or LPN may say or do something that appears to be publicly challenging the supervisor's authority. For instance, correcting a nurse leader in the presence of colleagues can stir up personal insecurities, since the supervisor might get the impression that you think he or she is brainless. Such leaders are dangerous because they might feel the urge to retaliate by making their victims experience public humiliation.
Tips Nurses Can Use To Avoid Getting Entangled In Toxic Hospital Politics
Apply Prudence When Choosing Friends
Prudence is the ability to exercise caution and judgment in the decision-making process. It's advisable to first study the behavior of other nurses and how they relate with colleagues before bonding with them. You don't want to become friends with someone who will leak your confidential information in the presence of other colleagues.
Don't Announce Your Next Move
Coworkers that have settled into mediocrity by allowing themselves to get stuck in career stagnation feel envious of ambitious colleagues. It would be catastrophic to announce your intention of going back to medical school for a bridging program because envious colleagues might decide to taint your reputation to block promotions.
Be Completely Honest With Your Supervisors and Other Bosses
Supervisors respect workers who approach them directly to raise issues because it displays respect towards authority. It's also easier to find solutions where there's mutual respect compared to holding negotiations in a tense environment.
Murmuring about issues, on the other hand, is detrimental to one's career because it can rub an insecure supervisor the wrong way. He or she might think that you're trying to get other nurses to rebel against the supervisor's authority.
Protect Coworkers Who Are Suffering From Unwarranted Personal Attacks
Surviving toxic hospital politics is not a walk in the park because an individual has to stay vigilant to spot backstabbers. It's quite unfortunate that student nurses and newly graduated caregivers find themselves on the receiving end of toxic office politics because they lack someone to defend them.
The best way of eliminating such negativity is by rising to defend coworkers against malicious attacks. This involves exposing colleagues that might be trying to coerce other workers into serving their selfish interests.
Consider Resigning If The Workplace Is Overwhelmingly Toxic
Perhaps you've done your best to treat colleagues with respect however there's just so much backstabbing taking place that it hinders you from performing your work at maximum productivity. The best option is handing in your resignation because toxic environments are a hazard to mental health.
Toxic Hospital Politics Affect Everybody
The best way of eliminating toxic hospital politics is by ensuring that you avoid coworkers spreading negativity.


text:
Mom trainer game
Pokemon trainers can utilize their battle skills in the Trading Card Game, with real-life tournaments pitting competitors against each other, and a tweet showing just how far one Mom has come has gone viral. Caroline revealed that her Mom, Pam, initially asked if she could come along to play for a bit of fun, practicing how to do a proper coin flip before the tournament began.
Strong stylized on-screen as S. Strong features 20 contestants, which include 10 male trainers and 10 female trainees. The trainers work on helping their trainees improve their physical fitness, not only through losing weight but, according to the series, "achieving a balance between mind and body, and getting into shape both physically and mentally". After a series of challenges, two teams will face each other in a physical competition in the Elimination Tower, with the losing team being eliminated from the series. The season one contestants for Strong include: [3]. Other executive producers include Sylvester Stallone and Kevin King-Templeton, both of whom also collaborated on the sports drama film Creed
Tiphany
My sex: I am woman
What is the color of my hair: Fair
I speak: French
What I like to listen: Hip hop
It was clear, right from the outset, that the upcoming TCG player wanted to learn and fast, with the support from members of the community attending the event. Congratulations, Trainer Pam! Hope to see you at Worlds one day…?? She knocked out a of competitions, including her own daughter, to progress to the latter stages of the competition, with the family sending out a warning to all other TCG competitors.
Pam is coming for you regionals, get ready? Whether or not Pam will actually go on to play cards at a major tournament like the Pokemon World Championships remains to be seen. But, if one day of light training managed to turn her into a Top 8 player in the first tournament, who knows what her future may hold in the game.
Gaming What is New World? Load More.
Archived from the original on May 28, May Health Coach". Archived from the original on April 23,
Hope to see you at Worlds one day…?? Archived from the original on April 23,
April 21,


text:
Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs
G. B. Toews, W. C. Vial, E. J. Hansen
Microbiology - Hansen Lab
We used a mouse model system to investigate the pulmonary defense mechanisms involved in clearance of nontypable Haemophilus influenzae from the lower respiratory tract. The importance of the C5 complement protein molecule in polymorphonuclear leukocyte (PMN) recruitment was studied by using congenic C5-sufficient B10.D2/nSn (C5+) and C5-deficient B10.D2/oSn (C5-) mice. The C5+ and C5- mice were inoculated with saline or nontypable H. influenzae via an endobronchial catheter. Clearance of bacteria was studied by using quantitative lung cultures. Bronchoalveolar lavage was performed at several time intervals. The number of cells in the lavage fluid were counted, and chemotactic activity was assayed in lavage fluid by the leading front technique, using human PMN in modified Boyden chambers. Pulmonary clearance of bacteria was significantly impaired in the absence of C5 (P < 0.05). The C5+ mice recruited significantly more PMN after challenge with nontypable H. influenzae than C5- mice did (P < 0.05), but significant PMN recruitment occurred in C5- mice. Similarly, although chemotactic activity was present in both C5+ and C5- mice, significantly more intraalveolar chemotactic activity was noted in C5+ mice than in C5- mice (P < 0.05). The C5 molecule yields important chemotaxins during this early time period, but other chemotaxins are also present within the alveoli, demonstrating the redundancy of the inflammatory response after pulmonary challenge with nontypable H. influenzae. Nitrogen mustard-induced neutropenic animals were studied to evaluate the functional importance of PMN in pulmonary clearance of nontypable H. influenzae. Pulmonary clearance of nontypable H. influenzae was significantly impaired in neutropenic animals (P < 0.05). Our results indicate that the prompt appearance of PMN in lungs is crucial for early clearance of nontypable H. influenzae.
Neutrophils
Therapeutic Irrigation
Chemotactic Factors
Mechlorethamine
Bronchoalveolar Lavage
Complement System Proteins
Toews, G. B., Vial, W. C., & Hansen, E. J. (1985). Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs. Infection and Immunity, 50(1), 207-212.
Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs. / Toews, G. B.; Vial, W. C.; Hansen, E. J.
In: Infection and Immunity, Vol. 50, No. 1, 1985, p. 207-212.
Toews, GB, Vial, WC & Hansen, EJ 1985, 'Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs', Infection and Immunity, vol. 50, no. 1, pp. 207-212.
Toews GB, Vial WC, Hansen EJ. Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs. Infection and Immunity. 1985;50(1):207-212.
Toews, G. B. ; Vial, W. C. ; Hansen, E. J. / Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs. In: Infection and Immunity. 1985 ; Vol. 50, No. 1. pp. 207-212.
@article{ed54384d1bd142aaaddd04a626c26696,
title = "Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs",
abstract = "We used a mouse model system to investigate the pulmonary defense mechanisms involved in clearance of nontypable Haemophilus influenzae from the lower respiratory tract. The importance of the C5 complement protein molecule in polymorphonuclear leukocyte (PMN) recruitment was studied by using congenic C5-sufficient B10.D2/nSn (C5+) and C5-deficient B10.D2/oSn (C5-) mice. The C5+ and C5- mice were inoculated with saline or nontypable H. influenzae via an endobronchial catheter. Clearance of bacteria was studied by using quantitative lung cultures. Bronchoalveolar lavage was performed at several time intervals. The number of cells in the lavage fluid were counted, and chemotactic activity was assayed in lavage fluid by the leading front technique, using human PMN in modified Boyden chambers. Pulmonary clearance of bacteria was significantly impaired in the absence of C5 (P < 0.05). The C5+ mice recruited significantly more PMN after challenge with nontypable H. influenzae than C5- mice did (P < 0.05), but significant PMN recruitment occurred in C5- mice. Similarly, although chemotactic activity was present in both C5+ and C5- mice, significantly more intraalveolar chemotactic activity was noted in C5+ mice than in C5- mice (P < 0.05). The C5 molecule yields important chemotaxins during this early time period, but other chemotaxins are also present within the alveoli, demonstrating the redundancy of the inflammatory response after pulmonary challenge with nontypable H. influenzae. Nitrogen mustard-induced neutropenic animals were studied to evaluate the functional importance of PMN in pulmonary clearance of nontypable H. influenzae. Pulmonary clearance of nontypable H. influenzae was significantly impaired in neutropenic animals (P < 0.05). Our results indicate that the prompt appearance of PMN in lungs is crucial for early clearance of nontypable H. influenzae.",
author = "Toews, {G. B.} and Vial, {W. C.} and Hansen, {E. J.}",
T1 - Role of C5 and recruited neutrophils in early clearance of nontypable Haemophilus influenzae from murine lungs
AU - Toews, G. B.
AU - Vial, W. C.
AU - Hansen, E. J.
N2 - We used a mouse model system to investigate the pulmonary defense mechanisms involved in clearance of nontypable Haemophilus influenzae from the lower respiratory tract. The importance of the C5 complement protein molecule in polymorphonuclear leukocyte (PMN) recruitment was studied by using congenic C5-sufficient B10.D2/nSn (C5+) and C5-deficient B10.D2/oSn (C5-) mice. The C5+ and C5- mice were inoculated with saline or nontypable H. influenzae via an endobronchial catheter. Clearance of bacteria was studied by using quantitative lung cultures. Bronchoalveolar lavage was performed at several time intervals. The number of cells in the lavage fluid were counted, and chemotactic activity was assayed in lavage fluid by the leading front technique, using human PMN in modified Boyden chambers. Pulmonary clearance of bacteria was significantly impaired in the absence of C5 (P < 0.05). The C5+ mice recruited significantly more PMN after challenge with nontypable H. influenzae than C5- mice did (P < 0.05), but significant PMN recruitment occurred in C5- mice. Similarly, although chemotactic activity was present in both C5+ and C5- mice, significantly more intraalveolar chemotactic activity was noted in C5+ mice than in C5- mice (P < 0.05). The C5 molecule yields important chemotaxins during this early time period, but other chemotaxins are also present within the alveoli, demonstrating the redundancy of the inflammatory response after pulmonary challenge with nontypable H. influenzae. Nitrogen mustard-induced neutropenic animals were studied to evaluate the functional importance of PMN in pulmonary clearance of nontypable H. influenzae. Pulmonary clearance of nontypable H. influenzae was significantly impaired in neutropenic animals (P < 0.05). Our results indicate that the prompt appearance of PMN in lungs is crucial for early clearance of nontypable H. influenzae.
AB - We used a mouse model system to investigate the pulmonary defense mechanisms involved in clearance of nontypable Haemophilus influenzae from the lower respiratory tract. The importance of the C5 complement protein molecule in polymorphonuclear leukocyte (PMN) recruitment was studied by using congenic C5-sufficient B10.D2/nSn (C5+) and C5-deficient B10.D2/oSn (C5-) mice. The C5+ and C5- mice were inoculated with saline or nontypable H. influenzae via an endobronchial catheter. Clearance of bacteria was studied by using quantitative lung cultures. Bronchoalveolar lavage was performed at several time intervals. The number of cells in the lavage fluid were counted, and chemotactic activity was assayed in lavage fluid by the leading front technique, using human PMN in modified Boyden chambers. Pulmonary clearance of bacteria was significantly impaired in the absence of C5 (P < 0.05). The C5+ mice recruited significantly more PMN after challenge with nontypable H. influenzae than C5- mice did (P < 0.05), but significant PMN recruitment occurred in C5- mice. Similarly, although chemotactic activity was present in both C5+ and C5- mice, significantly more intraalveolar chemotactic activity was noted in C5+ mice than in C5- mice (P < 0.05). The C5 molecule yields important chemotaxins during this early time period, but other chemotaxins are also present within the alveoli, demonstrating the redundancy of the inflammatory response after pulmonary challenge with nontypable H. influenzae. Nitrogen mustard-induced neutropenic animals were studied to evaluate the functional importance of PMN in pulmonary clearance of nontypable H. influenzae. Pulmonary clearance of nontypable H. influenzae was significantly impaired in neutropenic animals (P < 0.05). Our results indicate that the prompt appearance of PMN in lungs is crucial for early clearance of nontypable H. influenzae.


text: lgz – codice ISO 639-3 della lingua ligeza

redpajama_set_name: RedPajamaWikipedia


Escorting your companions on the Valentine's Day is something that everyone wishes for. You want to have a different idea to celebrate the day, probably a weird one. There have been many popular ideas over the years.
Most of the people want to celebrate Valentine's Day on a candle light dinner, where you might be holding hands making promises to stay forever in the future with your accompanying companion. Another popular and most common idea is to buy chocolates for your unique lover and a bouquet to wish him/her the very best of that day. Wherever you are, you like escorting your partners on that day. If your escorting lover is far from you, you order a cake or a perfume for him/her.
People have some unique ideas to celebrate it too. They might take their special companion on the terrace and celebrate it there dancing all night and drinking wine. Some may take a hot air balloon to fly high with their loving partners, watching beautiful valleys and farms. Others also like going for swimming with their lovely companions and having a candle light dinner on the beach.
There can be many vague ideas; presenting your escorting companion with a ring wrapped in a toffee wrapper or hidden in the roasted goose she is about to eat are amazing idea.
The main idea behind giving the gift is to surprise your escorting companion.
1. You want to make him/her surprised so he/she can love you more.
2. You want to impress your lover, you want to make him know how special and caring are you.
3. You somehow want to make those moments special and cherishing with your escorting partner.
4. You want to give him the confidence that you are the best choice for him.
5. You want to make him/her happier.
6. You want to know the place you hold for your lover in your heart.
7. You want to earn her love and respect and want your escorting partner to believe in you.


text:
Life of William Grimes, the Runaway Slave
Vendor: William L. Andrews
Life of William Grimes, the Runaway Slave is the first fugitive slave narrative in American history. Because Grimes wrote and published his narrative on his own, without deference to white editors, publishers, or sponsors, his Life has an immediacy, candor, and no-holds-barred realism unparalleled in the famous antebellum slave narratives of the period. This edition of Grimes's autobiography represents a historic partnership between noted scholar of the African American slave narrative, William L. Andrews, and Regina Mason, Grimes's great-great-great-granddaughter. Their extensive historical and genealogical research has produced an authoritative, copiously annotated text that features pages from an original Grimes family Bible, transcriptions of the 1824 correspondence that set the terms for the author's self-purchase in Connecticut (nine years after his escape from Savannah, Georgia), and many other striking images that invoke the life and times of William Grimes.
Author: Andrews, William L.
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Binding Type: PaperbackAuthor: Stewart, KennethPublished: 05/23/2021Publisher: Covenant BooksISBN: 9781646706730Pages: 190Weight: 0.77lbsSize: 9.00h x 6.00w x 0.52d
D. John Jackson
What About Me: Walking the Tightrope as a Black Man in America
Have you ever felt unseen, unheard, misjudged, or misunderstood?In What About Me: Walking the Tightrope as a Black Man in America, D. John Jackson, a Fortune 50 corporate leader with over thirty...
Bevy Smith
Bevelations: Lessons from a Mutha, Auntie, Bestie
Bevy knows what's what, and she is the kind of woman you want in your corner. If you don't believe me . . . buy the book. --Whoopi Goldberg Funny,...
This Is My Story, This Is My Song, This Is My Miracle
"This Is My Story, This Is My Song, This Is My Miracle" is an enlightening, inspirational, and historically significant manuscript that follows the genealogical heritage of James Story, a recognized...


The original "people's park", Victoria Park was established in response to the acute public health need of 19th-century East Enders for a large chunk of leafy greenness. The first park in the world built for a community, more than 150 years later it continues to attract millions of visitors – and with good reason. Two cafes, picnicking, foodie events, children's play areas, boating, tree walks, sports pitches, a bowling green and wildlife-education activities mean something for everyone.


text:
ACCEPTED

#### According to
Index Fungorum

#### Published in
in Chardón & Toro, Anal. Mus. nac. Hist. nat. B. Aires 20: 428 (1934)

#### Original name
Cercosporina stenolobiicola Speg.

### Remarks
null

redpajama_set_name: RedPajamaGithub


Following a 2-day meeting, the US FED expectedly voted to keep its benchmark interest rate unchanged at 1.00%-1.25%. The Fed's statement after the meeting however hinted on one more rate hike in 2017 and guided on plans to begin unwinding its Balance sheet starting from October 2017. Also, ahead of the OPEC meeting in Vienna scheduled for today, global oil prices have continued to trade above US$55.00/b as oil traders await the outcome of the meeting.
Notwithstanding, performance of global equity indices under our watch was largely positive as 10 of 16 indices closed the week in the green. In the developed markets, performance was mixed, with the US NASDAQ down 0.4% WTD as of writing while the S&P 500 traded flat WTD after reaching an all-time high earlier in the week. The low investor appetite is majorly attributable to unexpectedly hawkish statement from the US Fed as well as increasing tension between North Korea and the United States. Sentiment in the UK was however bullish, with the UK FTSE up 0.7% WTD as investors anticipate a reconciliatory speech from Prime Minster Theresa May in Florence.
Performance in the Eurasian region was positive as indices under our coverage closed in the green. Despite rising North Korean threats, the Japan Nikkei led advancers with a WTD return of 1.9% while the France CAC posted gains of 1.4% WTD. Ahead of the German 2017 election scheduled to hold on Sunday, the German DAX as of writing is up 0.9% WTD.
Sentiment was mixed across BRICS markets, with the South African FTSE/JSE up 0.3% W-o-W as the South African Reserve Bank voted to keep its benchmark rate unchanged at 6.75% amid higher inflation expectation. Likewise, the Russia RTS followed with 0.1% gain WTD. The India BSE SENS fell 1.1% WTD while the Brazil Ibovespa lost 0.2% WTD despite recent gains in oil prices. The China SHANGHAI closed flattish WTD.
In the African Region, performance was mixed as 2 of 4 indices trended northward W-o-W. The Egypt EGX 30 advanced the most, up 1.9% while the Nigerian All Share Index rose 0.6% on account of bargain hunting in stocks which had previously declined. On the contrary, the Ghana GSE COMPOSITE shed 1.3%W-o-W while the KENYA NSE 20 lost 0.2% as Kenyan electoral commission rescheduled the Presidential poll for October 26.
In line with expectation, the local Bourse advanced this week as the All Share Index (ASI) gained 1.4% W-o-W to close at 35,488.81 points while YTD gain expanded to 32.1%. Likewise, market capitalization added N165.8bn to close at N12.2tn. Activity level also improved as average volume and value traded strengthened 23.0% and 17.5% W-o-W to 219.2m units and N3.6bn respectively. Nonetheless the positive close of the benchmark index and strong activity level, sentiment was mixed during the week as the ASI rose on 2 of 5 sessions. The week started off on a negative note, with the ASI closing lower on the first two trading sessions (down 38bps and 8bps respectively) as investors continued to book profit in large caps across sectors. By Wednesday, the ASI rebounded 1.0% on account of a rally in DANGCEM. However, the market pared gains on Thursday (down 5bps) as investors quickly booked profit in DANGCEM. Friday saw a positive close as investors positioned in previous decliners.
Sector Performance was mixed as 3 of 5 indices rose W-o-W. The Industrial Goods index led gainers, up 2.9% W-o-W on account of appreciation in DANGCEM (+3.5%) and WAPCO (+3.0%). The Banking index closely followed, rising 2.4% W-o-W as a result of an uptick in GUARANTY (+7.0%) while the Insurance index climbed 1.4% W-o-W due to gains in LINKASSURE (+15.8%) and CONTINSURE (+9.8%). Conversely, losses in SEPLAT (-6.4%) OANDO (-3.6%), DANGFLOUR (-3.9%) and NIGERIAN BREWERIES (-2.3%) dragged the Oil & Gas and Consumer Goods indices 3.0% and 0.2% lower W-o-W.
Investor sentiment as measured by market breadth retreated to 0.5x (against 0.6x recorded last week) as 18 stocks advanced against 39 that declined. The best performing stocks were LINKASSURE (+15.8%), CONTINSURE (+9.8%) and CILEASING (+5.8%) while NEIMETH (-15.8%), CAVERTON (-9.2%) and UNITY (-7.1%) were the worst performers. Pending the start of Q3:2017 earnings season, market will likely continue to trade sideways. However, with the Quarter drawing to a close next week, we expect the local Bourse to close positive as fund managers rebalance portfolios.
Even as liquidity levels stayed tight all through the week, money market rates traded within a tight band between Monday and Thursday but surged on Friday. In addition, despite system liquidity in deficit on all trading days of the week, the Apex bank continued with its daily OMO mop-ups which took place on four days of the week. On Monday, Open Buy Back (OBB) and Overnight (OVN) rates eased marginally to 10.3% and 11.4% from 11.3% and 12.2% respectively due to inflow of bond coupon payment which offset wholesale FX auction announced same day. In addition, the CBN conducted an OMO auction in which a total of N60.0bn was offered but subscription stood at N17.6bn which was allocated in full. OBB and OVN trended lower on Tuesday to 9.5% and 10.3% respectively as system liquidity improved due to refund from retail SMIS auction. Similar to Monday, another OMO auction was floated in which N60.0bn was offered while total subscription and allocation stood at N14.9bn. Rates eased further on Wednesday but closed higher on Thursday at 10.7% (OBB) and 11.6% (OVN) as debits for the T-bills PMA (N215.9bn) held midweek and OMO auction (N207.7bn) offset the impact of the OMO maturity (N140.0bn). OBB and OVN surged to 35.0% and 38.0% at the close of the week, up 23.7% and 25.8% W-o-W respectively.
Activities in the Treasury bills market stayed soft this week on account of the weaker liquidity levels. On Monday, average rate on benchmark tenors settled at 17.6%, marginally down 1bp from the preceding Friday, as buy sentiment on shorter tenored instruments offset the impact of sell offs recorded across longer-dated bills. On Wednesday, there was a T-bills maturity of N140.9bn which was rolled over at the PMA. The CBN offered N28.1bn of the 91-Day (subscription: N23.3bn, Allotment: N22.8bn), N23.7bn of the 182-Day (subscription: N33.2bn, Allotment: N24.7bn) and N89.1bn of the 364-Day (subscription: N502.9bn, Allotment: N168.4bn) instruments at marginal rates of 13.2%, 16.8% and 17.0% respectively. Due to lower stop rates at the T-bills PMA and excess subscription for longer dated bills offered, sentiment was bullish on Thursday as average rate eased to 17.4% but increased to 17.5% on Friday, down 0.2% W-o-W.
In the coming week, we expect rates to remain at similar levels as an OMO maturity worth N123.5bn hits the system although we believe the CBN will continue with its OMO mop up.
The Naira strengthened at all segments of the FX market this week as the CBN sustained pace of intervention while foreign investors positioned at primary market sale of T-bills held mid-week. At the official market, the CBN continued with its weekly SMIS sales worth US$100.0m for spot and short tenured forwards under 60 Days while the Official rate improved from N305.95/US$1.00 the preceding Friday to N305.90/US$1.00 on Monday before eventually closing the week at N305.85/US$1.00. This implies a marginal 3bps appreciation W-o-W. Similarly, at the interbank market, the domestic currency depreciated from N354.99/US$1.00 on Monday to N356.99/US$1.00 on Wednesday, but strengthened to N353.50/US$1.00 by the close of the week, up 0.4% W-o-W. At the parallel market, the naira exchanged for N369.70/US$1.00 on Monday, strengthened to N367.00/US$1.00 on Tuesday and traded flattish till the end of the week, up 0.5% W-o-W. Activities at the I &E window improved during the week as total market turnover improved to US$959.4m (as of Thursday 21st September) from US$803.1m in the prior week while NAFEX rate strengthened to N360.39/US$1.00 from N360.25/US1.00 last week. The surge in activity level at the window reflects offshore investor interest in T-bills PMA held on Wednesday.
In the FMDQ OTC Futures market, the total value of open contracts fell by US$68.2m to settle at US$2.6bn this week. The SEP 20 2017 instrument worth US$383.3m matured during the week and was replaced with the SEP 26 2018 instrument. The most subscribed instrument is the DEC 27 2017 (US$372.4m) which currently trades at N356.91/US$1.00 while the least subscribed is the MAY 30 2018 (US$52.2m) which trades at N359.41/US$1.00.
Despite the spate of FX interventions by the CBN, the external reserves have remained on the uptrend, reaching a 31-month high of US$31.9bn on 14/09/2017. This accretion to the reserves has been largely due to the stability in oil prices as well as improved production volumes and we believe this will give the CBN more impetus to continue with its interventions. In the coming week, we expect rates to remain stable at the various segments of the market, even as we look towards possible discussions on FX market at the MPC meeting.
The bullish sentiment in the domestic bond market which has lasted for two weeks extended to this week's trading sessions with increased buying interest observed across tenors. Earlier in the week, market performance was characterised by sell offs across tenors before the trend was reversed by mid-week and sustained till the end of the week. Activity on the first trading the day of the week was soft as average yield across Benchmark bonds opened the week flat at 16.3% (same as the preceding Friday) as buy interest in the JAN 2022 instrument (-8bps) was broadly offset by sell offs in the MAR 2027 (+8bps) instrument. Average yield marginally increased 1bp on Tuesday as sell sentiment on the JUN 2019 (+7bps) and APR 2037 (+5bps) bonds outweighed interest in the JAN 2022 (-5bps) instrument. However, performance was bullish on Wednesday and Thursday due to improved Investor appetite on account of the expectation of lower stop rates at the T-bills PMA executed on Wednesday; hence, we observed increased buying across the yield curve which drove yields 6bps downward on average on Wednesday and a further 15bps on Thursday to eventually settle at 16.1%. The bullish trend lingered into Friday as average yield closed the week at 16.1%, down 0.5% W-o-W. In the coming week we expect to see a bearish performance at the start of the week as investors free up funds to partake in the September Bond auction.
The bearish performance witnessed across SSA Eurobonds was sustained this week as US Fed Chairman guided on one additional rate hike in 2017 and released measures to unwind its US$4.5tn balance sheet. Consequently, yields rose across all trading SSA Eurobonds, save for the GHANA 2017 (-2.6%) and GABON 2017 (-0.4%). The largest sell offs were recorded in the ZAMBIA 2024 (+28bps), ZAMBIA 2022 (+27bps) and SOUTH AFRICA 2019 (+24bps) Eurobonds. The NIGERIA 2023, KENYA 2024 and ZAMBIA 2024 remain the best performing YTD with returns of 9.1%, 8.5% and 8.0% respectively.
Similarly, performance across the Nigerian corporate Eurobonds was bearish as sell offs were recorded across all instruments save for the ZENITH 2019 (down 10bps W-o-W to 5.1%), GUARANTY 2018 (down 1bp W-o-W to 4.2%) and ZENITH 2022 (down 1bp to 6.5%). As the market continues to price-in monetary policy expectation on valuation, we expect performance to remain bearish in the near term.


Parse Applicants and Contacts into your BrightMove account on any page viewable in your browser.
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David Jarman at Daily Kos Elections (don't read the site?; you should!) provides a comprehensive rebuttal to the loony argument that Democrats trying to turn affluent suburbs blue are biting into the poison apple.
I'm going to propose a counterargument that may blow some minds with how off-the-wall it is: Maybe Democrats should contest as many races as possible, and try to win elections in as many places as possible, regardless of income, education, or race. There are different aspects to the Democratic agenda that can appeal to different types of people, and historically, electoral success for one party or the other has generally relied on putting up a big tent that can house a broad coalition capable of earning and sustaining a majority.
Moreover, this isn't the right time to be writing off any seats or any capable Democratic candidates because they're too hot or too cold. Given the existential threats to American democracy currently posed by those in charge of Washington, DC, I can't even imagine the level of detached privilege that would lead one to say that we shouldn't try to target some of the seats that are likeliest right now to fall into our grasp, and instead focus on the groundwork for a purer and more perfect party at some point in the future."
[T]here's been a lot of recent research showing that college-educated whites (presumably, the authors' vision of who lives in these affluent suburbs) are now somewhat more liberal in their policy preferences than non-college-educated whites. This is a reversal from, say, the mid-to-late 20th century. You can see this if you look at the changes in county-level election results over the decades, broken out by education level. You can also see it if you look at long-term studies that track the electorate's views over time.
Researcher Sean McElwee has been one of the main proponents of this line of thought; he's used data from the American National Election Studies (a long-term polling project conducted by political scientists that asks a battery of demographic and policy questions) to show that college-educated whites are now more liberal on questions about progressive economic policies than non-college whites are.
For instance, college-educated whites answer "yes" at a higher rate to questions like "Favor millionaires' tax," "Government should reduce inequality," and "More regulation of banks." Similarly, Democratic primary voters have become significantly less racist in the last decade: The number of Democrats who "strongly disagree" with the proposition that "If black people would try harder, they could be just as well off as whites" shot up between 2008 and 2016."
"[A]re people who've won the housing lottery via either privilege or simply by virtue of having gotten there first, but who are generally progressive in their values and policy preferences—who, at the national level, want a more equitable tax system, who want a higher minimum wage, who want more government involvement in providing health care to everyone, and above all, who want a non-embarrassing, non-threatening president, but who are NIMBYish in their beliefs about their own neighborhood—to be welcomed into the big tent, even though they're imperfect? Or are they to be cast aside in pursuit of a Democratic Party unicorn that looks more like the one of old—when, it should be pointed out, they repeatedly lost presidential elections, under the banner of fellows like Adlai Stevenson, Walter Mondale, and George McGovern? I know which one I'd prefer."
Me too. And so should you.


Relationship between the anticoagulant and antithrombotic effects of heparin in experimental venous thrombosis.
The relationship between the antithrombotic and anticoagulant effects of heparin was assessed using venous thrombi in rabbits. Accretion of 125I-fibrinogen onto jugular vein thrombi was used to assess the antithrombotic effect of heparin, and the protamine sulfate titration test (heparin activity) and the activated partial thromboplastin time (APTT) were used to measure its anticoagulant effect. The effect of heparin on jugular vein bleeding times was also measured in a separate group of animals. Fibrinogen accretion was significantly lower with continuous infusion than with intermittent injection. Heparin, given by continuous infusion, produced marked inhibition of fibrinogen accretion (to less than 10% of control accretion) at an APTT value of between 75 and 80 sec (control 34 sec) and at a level of heparin activity of 0.4-0.5 U/ml. Infusion of cryoprecipitate reduced the effect of heparin on the APTT relative to its effect on heparin activity. In these cryoprecipitate-treated animals, marked inhibition of fibrinogen accretion occurred at a similar level of heparin activity (0.4-0.6 U/ml) but at a significantly lower APTT (35-50 sec) than in normal animals. On the other hand, there was a progressive increase in jugular vein bleeding time with both increasing APTT values and heparin levels in both groups of animals.