(JFC) 22 For the third person plural pronoun, auvtw/n, one uncial and a few Latin and Syriac manuscripts read, autou, of which Metzger (TCGNT) says, "The Western reading, auvth/j, can be regarded as a transcriptional error for auvtw/n (in cursive Greek script the pronoun was abbreviated auvt with the termination expressed by a 'shorthand' stroke), or as a deliberate modification, introduced because afterwards (ver. 27) Jesus is the object of the presentation in the Temple."
25 Instead of the printed euvlabh,j, devout, reverent, several Western Witnesses read, eusebhj, devout, godly, pious, reverent; so, what's the difference? Well, in Acts 22:12, the former is used as a "by the standard of the law," according to Arndt and Gingrich's translation of Bauer's Lexicon, who also refer to Acts 2:5 and 8:2 as well as to our text at hand. So, the change might be worth considering.
28 Between avgka,laj and kai, several important witnesses insert autou, while almost as many such retain the received version, which does seem prudent to add, even if that makes the sentence longer, but by only one word. However, isn't it clear whose arms are meant here? Surely. So, perhaps keeping it shorter is the more likely original.
33 Where the relatively impersonal and unnamed, o` path.r auvtou/, occurs early in the sentence, several significant editors name Joseph, Iwshf, while, evidently, none names Mary, perhaps understandably for that culture's gender bias. Metzger points out that Joseph's name replaces the printed o` path.r auvtou, to preserve the doctrine of Jesus' virgin birth. Also, more reliable redactors keep the text as printed, so, the available evidence is hardly helpful in our attempt to get at the earliest form. And, again, similarly, some add that pronoun, autou, between mh,thr and qauma,zontej, while as just above many retain the printed account.
35 The third word in this verse, Îde.Ð, gets omitted by several dependable witnesses and retained by equally many. So, does the context need this word? Possibly it does and therefore could well have been original, but not necessarily?
38 On to the last word in this verse VIerousalh,m, many constant witnesses add a preposition, evn, while others change it to VIsrah,l, while still others retain the printed account. Metzger notes that the additional preposition "relieves the grammatical ambiguity, and the substitution of VIsrah,l, enhances the theological implications of the passage." So, since the redactions seem equal, the points Metzger makes seem plausible.
(JFC) 22 And when were fulfilled the days of the purification of them according to the law of Moses, they brought him to dedicate/present to the Lord, 23 according to what is written in the law of (the) Lord every male opening a womb holy/consecrated to the Lord shall be summoned/called/named, 24 and the giving of a sacrifice according to the sayings in the law of the Lord, a pair of doves or two young pigeons. 25 And behold a man was in Jerusalem whose name (was) Simeon and the man this one (was) righteous and devout awaiting (the) salvation/setting free of Israel, and (the) Spirit lived/rested/was holy on him; 26 and was to him to have been called/warned [passive, perfect, participle] by the Spirit of the holy not to see [aorist, active, infinitive] death before should appear the Christ of (the) Lord. 27 And he came in the Spirit to the temple; and in the to lead [aorist, passive, infinitive] these parents the child [accusative] Jesus to do [aorist, active, infinitive] unto him according to what was accustomed [perfect, passive, participle] of the law unto him 28 and he received/took him into the arms and praised the God and said; 29 "Now dismissing/releasing/setting free/ forgiving the servant of Yours, Master/Lord, according to the saying/promise of Yours in peace; 30 that saw the eyes of mine the salvation of Yours, 31 which You prepared according to the presence of all the peoples/nations, 32 a light unto the revelation of the nations/people and glory for people/nation of Israel." 33 And was the father of his and the mother are being amazed [present, active, participle] at the sayings concerning him. 34 And praised them Simeon and said to Mary the mother of his; "Behold, this one is destined unto fall and rise of many in this Israel and unto a sign contradicting [present, passive, participle] - 35 and of you yourself the life/psyche will go/pass through sorrow/sword - in order that might be revealed [aorist, passive, subjunctive] from many hearts' opinions. 36 And there was Anna a prophetess, daughter of Phanuel, from (the) tribe of Asher; she was old in days many, having lived with a man/husband having lived years seven after (the) virginity of hers 37 and she (was) a widow until years eighty-four, she never left the temple fasting an praying worshipping night and day. 38 And that very hour she appeared she gave thanks to the God and said/proclaimed concerning him all the waiting for (the) redemption of Jerusalem. 39 And as they finished all that according to the law of the Lord, they returned to the Galilee to the city of theirs Nazareth. 40 And the child grew [imperfect, passive, indicative] and became strong/matured (by) fulfilling wisdom, and (the) grace of God was upon him.


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The Competition & Commercial Law Review
We, at The Competition and Commercial Law Review (TCCLR), aim to stimulate and encourage discourse on topical issues pertaining to the sphere of competition law and other allied areas of corporate law. This platform is intended to be a junction, where academia and industry interact to yield effective solutions for contemporary issues in the field of competition and commercial law. TCCLR also aims to inculcate a culture of high-quality legal research in the field of competition and commercial laws and be an all-in-one web portal for practitioners and law students, keeping them abreast of the latest legal developments. The blog also intends to provide valuable insights into various legal intricacies and ways to tackle the possible predicaments through our flagship interview series, where we invite legal practitioners from across the world to share their experiences and suggestions for the budding lawyers.
Ms. Anisha Chand
Anisha Chand is currently a Partner in the Competition and Antitrust Practice Group at Khaitan & Co. Having graduated from Mumbai University, she has represented several clients across various sectors ranging from pharmaceuticals, automotive components, media and entertainment, financial services, agro-chemicals, cement, and information technology. A Resource Person (for merger control and abuse of dominance, with the Indian Institute of Corporate Affairs, she routinely writes for several domestic and international publications. She has been consistently recognized in Who's Who Legal- Future Leaders 2017, 2018, and 2019.
Dr. Rishab Gupta
Dr. Rishab Gupta, Partner at Shardul Amarchand Mangaldas, Mumbai is currently heading its international arbitration practice. After completing his J.D. from Columbia University School of Law, he received his DPhil (Ph.D.) from Balliol College, Oxford University where he was a Rhodes Scholar. Qualified to practice in India, the US, and the UK, Dr. Gupta has been recognized by Who's Who Legal 2018 and 2019 as a "future leader of arbitration." He is among a few lawyers in India with a strong experience in investment treaty arbitration where he regularly acts for foreign investors against States.
Ms. Almitra Gupta
Ms. Almitra Gupta is currently an Associate at Linklaters, Singapore in their Equity and Debt Markets practice. Having graduated from Government Law College, Mumbai, she started her practice with the capital markets team of Juris Corp and then moved to Cyril Amarchand Mangaldas. Later, she pursued an Executive LLM from King's College London, in 2017 and then moved to the U.S. to pursue her LLM from University of Pennsylvania along with a Business and Law certificate program from The Wharton School. Recently, she got admitted to practice with the New York State Supreme Court.
Ms. Ashrita Prasad Kotha
Ms. Ashrita Prasad Kotha is currently an Assistant Professor at O.P. Jindal Global University (JGU) and also a Ph.D. Candidate at WU (Vienna University of Economics and Business), Austria. She has completed her BCL from the University of Oxford as a KC Mahindra Scholar and previously worked as an Associate at L&L Partners . She is also a recipient of the Abe Greenbaum Fellowship for 2018 by School of Taxation and Business Law, University of New South Wales. Known for being intellectually stimulating and a reason behind her students taking up an ardent interest in the complex taxation space, she has been awarded the Research Excellence Award by O.P. Jindal Global University (JGU).
Ms. Nandini Pathak
Nandini Pathak is a Leader of the Investment Funds Practice at Nishith Desai Associates. A merit-cum-means scholarship holder, she is also recognized as one of the distinguished alumni of Jindal Global Law School, Sonipat, Haryana (India). With a strong focus on VC / PE funds, she has advised several international and domestic clients on legal, regulatory and tax issues, fund governance. Her expertise includes tax-efficient structuring for India focused funds as well as LP negotiations. With a strong practice base on the fund formation side, she also regularly advises clients on the regulatory front including securities laws and exchange control.
Mr. Vinay Shukla
Mr. Shukla is currently a Senior Member of the Competition Law Practice at Nishith Desai Associates, a research-based international law firm. Having graduated from Hidayatullah National Law University, Raipur, he has represented some of the ace investors in securing various merger approvals including green channel approvals from the CCI. He also represented an investor in the divestment of Reliance Jio's telecom tower assets. Often seen providing his valuable insights in Business Standard on various changes in the antitrust regime, he has a strong inclination towards the working of competition laws in this era of the digital economy.
Mr. Akshay Pathak
Mr. Pathak is currently a Senior Associate at Cyril Amarchand Mangaldas. He has previously worked with Shardul Amarchand Mangaldas & Co. In addition to his impeccable academic record, he has some commendable mooting achievements. He has also made his mark in publications with his articles featuring in various national and international journals of repute. Interestingly, he has also been the recipient of the Best Student twice in addition to winning several accolades in national seminars. Moreover, he has also judged the national rounds of prestigious moot court competitions such as Jessup & Stetson.
Ms. Hrideja Shah
Ms. Shah is a dual-qualified lawyer based in California and India. Having graduated from Jindal Global Law School, she completed Master of Laws from the University of California, Berkeley. Furthermore, she passed the much-coveted California Bar exam. Before joining University of California, Berkeley, she had worked at Crawford Bayley in their Intellectual Property and Capital Market teams. She also happens to be the Founder of Legal Sollis - An online legal forum dedicated to helping students, as well as professionals, improving their legal research & writing skills. She has also been the recipient of the Best Research award during her undergraduate days.
Mr. Saurav Bhaumik
Mr. Bhaumik is currently an Associate at Khaitan & Co. specializing in M&A transactions. Having graduated from NUSRL, he completed his MSc in Law and Finance from the University of Oxford, England. He has previously worked with top-tier law firms such as L&L Partners (Formerly Luthra & Luthra Law Offices) and Shardul Amarchand Mangaldas & Co. He has also to his credit numerous articles published in various reputed journals and blogs. Few of his articles feature in highly reputed portals such as SAGE, Oxford Business Law Blog, Bloomberg Quint, Wolter Kluwers, Indian Business Law Journal, etc.
Ms. Swati Sharma
Ms. Sharma is currently working with the Competition Law team at P&A Law Offices. She has also worked as a Research Associate - Competition Law at the CUTS Institute for Regulation and Competition, CIRC and the National Law University, Delhi. She is an alumnus of Faculty of Law, Delhi University and has also been a part of various competition advocacy initiatives. Ms. Sharma is also engaged with the University of Central Lancashire where she contributes to India related research and publications focusing on trade and competition law issues.
Dibya Prakash Behera
Founder Editor
Vishal Rajvansh
Dibya is currently an Associate at Nishith Desai Associates in its Investment Funds practice team. Having graduated from the National University of Study and Research in Law, Ranchi in July 2020, Dibya boasts of an impressive CV with top tier law firm internships, national & international mooting achievements, and an enviable set of publications. With close to 25 publications, his articles feature in some of the world's most renowned blogs such as King's Student Law Review, Cambridge International Law Journal, Berkeley International Law Journal, Concurrences (New York), European Competition Law Review, IndiaCorpLaw, CorpLawAdviser, SCC Online, The Practical Lawyer, etc.
A third-year student at NUSRL, Vishal has an ardent interest in competition law serving as an inspiration behind founding this blog. Given his flair for writing, he has a stellar publication record with his articles featuring in reputed international portals such as Cambridge International Law Journal, Berkeley International Law Journal, Concurrences (New York), European Competition Law Review, IndiaCorpLaw, Taxmann, etc. He also runs a poetry page by the name of blunt_poetry on Instagram.
Akshay Anurag
Rajarshi Singh
Navantak Agrawal
Blog Secretary
Soon after graduating from NUSRL, Akshay will be joining Singh and Associates, Gurugram in its dispute resolution team. Along with an impeccable academic record, Akshay is credited with more than fifteen publications in various reputed journals/blogs such as Corporate Professional Today, SEBI and Corporate Law magazine, Society of International Law and Policy (NUJS), SCC Online, All India Reporter, Manupatra etc. He also runs a photography page by the name _blurred.lines__ on Instagram.
A fourth-year student at NUSRL, Rajarshi has an inclination towards ADR. A reader, an author, and an avid mooter, he has represented his University in several moot court competitions of international repute such as the 59th Philip C. Jessup International Moot Court Competition, 10th Leiden Sarin International Air Law Moot and the 6th Herbert Smith Freehills Competition Law Moot. Interested in investment arbitration, he regularly writes for several national and international forums on this niche subject.
A second-year student at NUSRL. Navantak has a keen interest in the field of Intellectual Property Law and has interned at few reputed law firms. He has also completed numerous certified courses on Copyright and Trademarks, offered by University of Pennsylvania. Navantak has also made his mark in the publications space with his articles featuring in the reputed blogs such as Taxmann, Manupatra, IJLPP etc. Being a tech geek, he has a strong inclination towards cyber law and development of information technology.
©2020 by The Competition and Commercial Law Review.

redpajama_set_name: RedPajamaCommonCrawl


Under the Senior Maintenance Officer, this section is charged with the responsibility of maintaining all University physical facilities such as teaching and learning facilities (including theatres, laboratories, field stations, and lecture halls), offices, and residential houses (including students' halls of residence and related physical facilities and residential houses for staff.
Through formal requests by the user department/institute/school/college by filling the Maintenance Request form (commonly referred to as M1).
In most cases, the process of maintenance on receiving an M1 would start with taking specifications through technical staff moving to site and identifying the required correction and/or material. The identified requirements are submitted to Procurement Section whose responsibility would be to supply them to the Department upon which repair/maintenance process commences. On completion, and after making sure that the area is cleared of any debris and making good any damage occasioned during the process, the completed work is handed over after the user certifies that he/she is satisfied with the work. If not, further work to the satisfaction of the user continues.


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Jeff Kaufman
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Shared House Setup
In my post on helping Lily make dinner I talked about how there were eight people in the house, and someone wrote to me to ask how this works and how we ended up with that arrangement.
We've been living in group households for most of the last ten years: with another couple and their baby in East Somerville; with a rotating group of parents, sisters, in-laws, niblings, cousins, and friends in West Medford; and our current setup in West Somerville. In the early 2010s, Julia and I were thinking about different ways of having a more long-term arrangement, and we decided on buying a large house and renting to friends. Ideally something with multiple units, so we'd have more flexibility if at some point we wanted a different arrangement.
In August 2014 my college friend David saw two posts of ours and was thinking some about communal housing. We wrote back and forth some, and I encouraged them to consider moving to Boston and living with us. At the time it didn't seem like it made sense for them, though.
Julia and I had been looking at multi-family houses in Somerville and Cambridge, and in September 2014 we made an offer on a West Somerville two-family (though the closing ended up being delayed until mid-February). We talked more to David and their partner Al, and they decided to come be housemates with us.
Initially the house had a downstairs unit with two bedrooms and one bathroom, and an upstairs unit with "four" bedrooms and one bathroom. That's "four" because you had to walk through one bedroom to get to another, which would normally be a large downside but ended up being a good fit for David and Al's needs. Julia and I took the other two bedrooms, and the previous tenants stayed on in the downstairs unit.
We made some changes to the house to make it work better with more people: I added a second bathroom to the upstairs unit, I converted part of the front hall to be an home office for Julia, we had dormers built giving two more bedrooms on the upstairs unit, and then I added a hallway to allow the "pass-through" bedroom to be used independently.
After a while friends moved into the first floor two-bedroom, and then when they moved out David and Al moved downstairs and Ruthie moved in upstairs. We also have had a series of au pairs who've lived upstairs with us as well, taking care of the kids.
We do communal food, with a house grocery card and splitting the expenses N ways, and the adults each cook house dinner one night a week. Normally I do most of the groceries, though on a best-effort do-it-when-convenient sort of basis, but since we're not going inside places right now it's a bit different. I've been putting in orders for anything that's available at a reasonable price and quantity from a restaurant supplier (and coordinating with others to distribute bulk goods at the same time), and Julia has been handling Instacart orders for the rest.
Chores are mostly not explicitly arranged, with people generally just trying to do their share. We used to have a more specific arrangement, but as we've gotten used to living together it's seemed less necessary. At some point if things weren't going as well we might try switching back to a more explicit system. Tidying is mostly me and Julia, since the untidying is mostly our kids.
Since Julia and I own the building we're in the landlord role, paying for the house, dealing with landlordish problems when they come up, and charging rent to the others. The goal is for rent to vary with the local market, and I expect the next time we revisit rent it will be going down a lot based on changing local conditions. Especially if colleges are still remote in the fall.
Our housemates (and our au pair when she's off) don't have any childcare responsibilities, though the kids will make requests and people can decide whether to oblige. When Lily was little there was a lot of "can I watch a video on your phone?", while now there's more "can I come down and play the Goose Game?"
Overall I like this a lot. It's a good balance of having enough people around to be interesting, but not so many that there's a lot of conflicting preferences.
Really Fresh Baking Kids and Moral Agency
Comment via: facebook, lesswrong
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How did we decide to have a kid?
...and then some more kids? The post How did we decide to have a kid? appeared first on Otherwise.
via Otherwise January 28, 2023
My Rainbow Kit
For Christmas I got a really fun kit about rainbows. It had a rainbow catcher, a really cool necklace, a streamer thingy, and it also had a really really cool pinwheel, and it also had a bracelet and a pinata. Unfortunately the pinata didn't work out …
via Anna Wise's Blog Posts January 5, 2023
I think that once a kid is in third grade they should be able to get a phone. I think that while sometimes parents might want kids not to have them at certain ages, phones can be quite useful at times. Tablets don't have GPS, they don't have WiFi…
via Lily Wise's Blog Posts January 5, 2023
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Once again we had a fantastic holiday in Rachel's apartment. It's like a home from home but with better weather and wonderful views of the sea and sunset. It's a well-equipped apartment with everything you could possibly need. We are looking forward to October when we will be back.
Lovely Apartment, Fantastic location - Just returned from a weeks stay at this lovely apartment. My husband and I have holidayed in Playa Del Duque for many years and often wondered about the Altamira complex. We were not disappointed, the apartment was spacious, clean, comfortable and well equipped. Overlooking the lovely garden area of the complex, we could hear the sea and watch the sun go down from the lovely apartment terrace. The pool area is ideal for couples and families, clean with plenty of sun loungers. The location of this apartment was just perfect, within walking distance of the upmarket area of Del Duque and the lovely restaurants and bars overlooking the beach. We enjoyed our walk to La Caleta which is in the opposite direction and ate out at quite a few of the vendors recommended restaurants. If you are looking for a peaceful relaxing holiday I would highly recommend this apartment. We enjoyed it so much that we have booked to return next year. We had a fantastic week in your apartment it was exactly what we wanted. If we return to Tenerife we'll certainly consider you first.
Lovely El Duque Apartment -The apartment is in a stunning location amongst 5 star resorts and a short walk to the beach. The building is well maintained and Rachel's apartment had everything we needed. The pool area is very relaxing and we always managed to get a sun bed. Highly recommended accommodation.
Myself and my wife have stayed at Alatamira for several years before staying at Rachel's apartment. It is at the quiet end of the resort and very close to to Del Duque beach. Peace, quiet and sunshine is all we need and this apartment was perfect for all our holiday needs.This lovely 1 bedroom apartment was spotlessly clean and had everything you needed to make your stay a comfortable and enjoyable experience. Fridge, freezer, great shower and even English TV. Although the there was no AC there are 2 ceiling fans which do a good job in keeping you comfortable in the heat of the summer sun. Check in was effortless and the trip from the airport in a taxi costs approximately 30/35 euros. An added bonus was the polite and attentive nature of Rachel's communications and very prompt response time to any questions. She is a lovely lady who genuinely wants you to enjoy her lovely apartment and for you to have a great holiday. We were so happy and impressed we have already booked for next year. Highly recommended.
The apartment was absolutely lovely and the owner Rachel could not have been any more helpful. The arrival instructions and details of the local area were very detailed and extremely useful. The local area was lovely and the pool was gorgeous. The only concern we had was the beach directly to the front of the building is currently being refurbished, but once this has been completed the beach will also be stunning! This apartment & owner are Highly recommended!


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Family Fitness Day at Lompoc Track and Field
Written by Nora Wallace on 12 September 2022
Lompoc's first Family Health and Fitness Day will take place on Sept. 17, with plenty of free fun field activities, Zumba and yoga, and a host of community vendors.
The outdoor and family-friendly event will be held from 10 a.m. to 1 p.m. at the Lompoc Community Track and Field at Huyck Stadium at Lompoc High School.
Field activities will occur from 10 a.m. to 1 p.m., with Clau Elizabeth Zumba kicking off a high-energy routine at 10:30 a.m. Participants can try yoga with Blooming Energy at noon while making sure to take time to visit a wide array of community vendors for resources, information, giveaways, and more.
The day of outdoor fun is hosted by LVCHO's Healthy Lompoc Coalition, the Lompoc Hospital District Foundation, Lompoc Family YMCA, Lompoc Unified School District, and Route One Farmers Market.
The track is located at 515 W. College Ave.
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Scale and proportion are two design elements that help to create the atmosphere within a room. It's important for everything from the kitchen cabinets to the wall art to fit together properly and that is where scale and proportion comes into play when creating interior design.
Scale refers to how the items within the room relate to each other or to the room itself. Proportion is similar to scale but it refers to the shape and dimensions of the objects within a room and it's all about visual perception.
When you place an oversized dining room table in your den, leaving little room for anything else, this would be an example of something being out of scale. Placing a small, low-sitting sofa in a large living room with a high ceiling is another example. In order to achieve proper scale, you have to choose furnishings to match the space around them.
You have the option of customizing your home if someone in your family is extra short or tall. For example, if the cook in the family is very short, then you can customize your cabinets and make them lower than normal to make it easier for them to reach everything. If the man of the house is extra tall, you can install a higher than normal showerhead in the bathroom. You determine what scale fits your needs the best based on the individuals living in the home.
Placing a large TV on a small stand is an example of something being out of proportion because it would appear unbalanced when you look at it. You may even feel like it will topple over when you see it, which creates an uneasy feeling. When objects are proportioned correctly, everything will seem balanced and pleasing to look at and you will feel relaxed and comfortable.
Creating proportion with your interior design is different for every structure, which is why many people rely on professional interior designers and decorators to help them achieve the look they want. When you're ready to start your next project give us a call here at J. Design Group and we'll help you achieve proper scale and proportion within your interior design.
When creating scale and proportion with interior design, color plays as much of a role as size does. You can create illusions that make the room look larger or smaller simply by the color you use. For example, painting the ceiling white and the walls a light color or using wallpaper with vertical stripes will make small rooms with low ceilings appear larger. Decorating with simple patterns and small designs will also help make the room look bigger.
Painting the ceiling a darker color than the walls will help make large rooms with high ceilings look smaller. You can use bold patterns and lots of accessories to fill up the room to make it feel more cozy and comfortable.
When these two design elements are integrated correctly into the interior design, you'll create a warm and welcoming environment. However, when the items in the room are too small or too large for the space, it can make the room feel cold and uncomfortable.


la différence en termes de contrainte cardiovasculaire au cours de l'acte sexuel entre homme et femme. La cause du décès était un infarctus dans 28 cas, une récidive de nécrose dans 19 cas et un accident vasculaire cérébral hémorragique dans 7 cas. Il paraît intéressant de préciser que, dans la publication de 2001 , 36 décès sur les 48 constatés à l'époque (75 %) étaient survenus au cours de relations extraconjugales, en particulier avec des prostituées (n = 25). Les décès de femmes lors de relations extraconjugales sont en revanche particulièrement rares avec très peu de cas décrits dans la littérature . Cette augmentation du risque de complication cardiovasculaire au cours de l'activité sexuelle concerne l'acte sexuel lui-même et, globalement, les deux heures suivantes .
necrosis can be looked at as a good strategy induced by pathogenic mycobacteria to skew the protective host immune response. Since 2005, a novel form of proinflammatory programmed cell death, or pyroptosis, has been identified to be uniquely dependent on caspase-1, which is not involved in apoptosis, and prototypically induced by infection with flagellin-expressing bacteria, such as Salmonella and Shigella species . To date, pyroptosis seems to play a significant role in specific biological systems. It has been previously shown that this mechanism releases bacteria from macrophages and exposes the bacteria to uptake and killing by reactive oxygen species in neutrophils . Similarly, activation of caspase-1 cleared intracellular Legionella pneumophila and Burkholderia thailandensis in vivo by IL-1β-independent mechanisms, an efficient bactericidal mechanism by the innate immune system . In this study, we did not check whether pyroptotic cell death takes place in our system; however, based on the latest notion highlighted by those authors, the increased IL-1β levels found in the cultures could not support this possibility. With this in mind, and regarding M.
doses was real and not due to late sampling. However macaques primed with DNA/measles protein vaccines raise cytotoxic T-cell, IFN-γ and antibody responses within 14 days of challenge with live virus  and . Perhaps in our study the attenuated vaccine virus did not multiply sufficiently in the presence of antibody to raise a cell mediated immune response. There were no significant Bay 11-7085 differences in plasma cytokine levels between the groups before or after the 36 month booster dose which resulted in a significant fall in IL-10, IL-2Rα and MIP-1β concentrations in both groups after the boost. This was not mirrored by changes in FOXP3 mRNA expression which were expected to increase . We found no relationship between maternal or vaccine derived measles antibody concentrations and IFN-γ ELIspot numbers or cytokine levels after primary or secondary immunization. Similar findings have been noted following primary measles immunization in infants  or after secondary immunization in children  or after measles in children . Intracellular cytokine staining showed that CD4 and CD8 T-cells were equally prominent producers of IFN-γ during the effector response and that both cell types a produced IL-2 in memory responses.
SDS-PAGE analysis showed purity of >95%. Its functionality was verified by its ability to form the stable C3-convertase . The VCP http://www.selleckchem.com/products/epacadostat-incb024360.html specific mAbs were generated by immunizing 5–6 week old BALB/c mice with the rVCP. In brief, mice were immunized with 20 μg of rVCP in Freund's complete adjuvant, followed by two boosts 15 days post prime at weekly intervals with the same dose, but in Freund's incomplete adjuvant. Following immunization, spleen was removed and the spleen cells were fused in-house with myeloma cells as per established protocols  and . The clones from the fusion were screened by ELISA and subcloned to isolate the individual clones.
of individual time point per site. To study the role of complement during infection, similar experiments were also performed in two additional rabbits depleted of complement by administering 100 U/kg of cobra venom factor.
All the results were grouped and statistically evaluated by performing Mann–Whitney Rank Sum test (SigmaStat). The experimental protocol was approved by the Institute's Animal Care and Use Committee. The ELISA plates were coated overnight at 4 °C with rVCP or VCP mutants (CCP 1–3, CCP 2–4, CCP 1–2, CCP 2–3, CCP 3–4; 200 ng/well), blocked by adding 5% milk and incubated with mAbs (1 μg/well) for 1 h at room temperature. Binding was probed by adding 1:2000 diluted anti-mouse HRP conjugate (Biorad, Hercules, Tolmetin CA) and detected with 2,2′-Azino-bis (3-ethylbenzthiazoline) 6-sulfonic acid (ABTS) (Roche, Mannheim, Germany) at 414 nm. Inhibition of factor I cofactor activity of VCP by mAbs was determined as described below. rVCP (0.5 μg) was mixed with 3 μg of mAb and incubated for 15 min at 37 °C. Thereafter, 3 μg of C3b or C4b and 0.1 μg of factor I was added to the reaction mixture and the volume was adjusted to 20 μl using PBS. It was then further incubated at 37 °C for 2 h. The reaction was stopped by adding SDS-PAGE sample buffer containing DTT and C3b/C4b cleavages were analyzed on a 10% SDS-PAGE gel . Inhibition of the classical pathway decay-accelerating activity of VCP by mAbs was determined by utilizing a hemolytic assay  and .
The company has to assess the epidemiologic data and balance the costs. In Africa, opinion leaders support vaccine manufacturers, and investors can expect the economic improvement in the future. A. Muktadir from Incepta (Bangladesh), shared the story of how he started the business and illustrated the biggest challenges. One challenge comes from the PQ barrier because the local NRA is not considered fully functional. The simple motivation is to develop high quality vaccines for those people who need them. Dr. Muktadir expressed appreciation for the platform provided by DCVMN and expressed his interest in seeking partners for vaccine technology transfer to Bangladesh.
"An update of Intravacc's Sabin IPV technology Transfer Initiative to developing countries vaccine manufacturers as a Private Public Partnership directly under the Ministry of Health in The Netherlands was provided by A. Hamidi.
result in sustained Ag expression at the site of injection , in some cases more than 12 months , , ,  and , the exact contribution of this Ag to initiating and maintaining immune responses is far from clear. Phosphatidylinositol diacylglycerol-lyase The cell types engaged in antigen production following intramuscular pDNA injection are predominantly myocytes, although direct transfection of, and antigen expression by, haematopoietic cells (including CD11b+ cells) at the injection site, has been reported ,  and . Although it is believed that somatic cells such as myocytes serve as Ag factories, that continue to "tickle" naïve and perhaps memory cells, precisely how and when Ag gets from these Ag depots to CD4 and CD8 T cells in secondary lymphoid tissue is not clear.
is indicative of improved channeling of (pyruvate) glucose for mitochondrial oxidation. Glucose-6-phosphatase, a gluconeogenic enzyme, catalyzes the dephosphorylation of glucose-6-phosphate to glucose.51 Fructose-1, 6-bisphosphatase is another gluconeogenic enzyme that catalyzes the dephosphorylation of fructose-1, 6-bisphosphate to fructose-6-phosphate serves as a site for the regulation of gluconeogenesis.52 The increased activities of Sodium butyrate glucose-6-phosphatase and fructose-1, 6-diphosphatase in liver and kidney of the STZ induced diabetic rats may be due to insulin inadequacy. Upon treatment with the MFE the activities of glucose-6-phosphatase, fructose-1, 6-diphosphatase were found to be dwindled. This might be due to improved insulin secretion, which is responsible for the repression of the gluconeogenic key enzymes. Glucose-6-phosphate dehydrogenase is the rate-limiting enzyme of the pentose phosphate pathway.53 The activity of glucose-6-phosphate dehydrogenase is found to be decreased in diabetic conditions.54 Oral treatment of MFE to STZ induced diabetic rats significantly increased the activity of glucose-6-phosphate dehydrogenase. It seems to increase the influx of glucose into the pentose monophosphate shunt in an exertion to cut high blood glucose level.
of MSP142 expression. A549 cells in a 12-well plate were infected at 70% confluence with various adenovectors Epigenetic inhibitor at a MOI of 200 pu/cell for 1 h and then overlayed with DMEM medium containing 5% FBS. Twenty-four hours later, cells were trypinized, collected, and prepared for FACS analysis. For cell surface staining, cells were directly fixed with CytoFix/CytoPerm (BD Biosciences, San Jose, CA); for intracellular protein staining, Adenylyl cyclase cells were treated with cytoperm/cytofix (BD Biosciences) to fix and permeablize the cell membrane, prior to staining with the MSP-specific polyclonal antibody R94256. Glycosylation of AMA1 or MSP142 variants was analyzed with N-glycosidase PNGase F or Endo H (New England Biolabs, Ipswich, MA). PNGase F is an amidase that cleaves between the innermost GlcNAc and asparagine residues of complex oligosaccharides from N-linked glycoproteins. Endo H is a recombinant glycosidase which cleaves within the chitobiose core of high mannose and some hybrid oligosaccharides from N-linked glycoproteins. A549 cells at 80% confluence were infected at a MOI of 200 pu/cell with the indicated vectors expressing either AMA1 or MSP142. Twenty-four hours later the media was removed, the wells were washed 3 times with PBS and the cells were lysed in 3 ml of RIPA buffer (20 mM Tris [pH 7.4], 137 mM NaCl, 10% glycerol, 0.1% sodium dodecyl sulfate [SDS], 0.5% deoxycholate, 1% Triton X-100, 2 mM EDTA).
Use of P0 was found to improve the correlation as compared to the conventional in vitro Papp ( Avdeef, 2011). In Avdeef (2011), the IVIVC P0 analysis for published data from porcine models gave a correlation coefficient, r2 of 0.58 (P < 0.001).
ABL or paracellular limit), or when judgement has to be made to determine pKaFLUX AUY-922 price from assays for ionizable compounds conducted at a single pH of 7.4, which is common for BBB research. The low r2 may also reflect the use of pCEL-X predicted in situ P0 values (acetylsalicylic acid and neramexane) and Caco-2 values (dexamethasone and metoprolol) to fill in gaps in the rodent in situ brain perfusion database. The focus of the applications so far has been to derive or predict the transcellular passive permeability in vivo. Hence, in situ data for the training set were selected from studies which used transporter knock-out animals, transporter inhibitors or high concentration of compounds to saturate transporters Metalloexopeptidase ( Dagenais et al., 2009). Compounds reported to show saturable transport were excluded. In the present study, the assays for uptake compounds were not conducted in the presence of inhibitors or saturating concentrations.
Therefore, the permeability values obtained were in some cases different from predictions. The differences in transporter expression in different species (pig and rodent) and also in different models used i.e. in vitro and in vivo could also influence the r2. In the present study, the data collected reflect evolution of the in vitro PBEC model from a low TEER cell monolayer (below 200 Ω cm2) to high TEER cell monolayer (>1000 Ω cm2) used for permeability assays and the new knowledge of the restrictive effect of polyester filter membrane (Transwell®-Clear) on permeability of lipophilic compounds. The cell monolayer tightness and filter boundary define the DRW which influences P0 derivation, hence could also influence r2. The larger numbers of compounds in the IVIVC analysis in the present study cover a wider chemical space compared to the correlation analysis of ten compounds reported by Lundquist et al. (2002) which will also influence r2.
(Remi, Mumbai) for separation of serum. The serum was separated and used for assay of Alanine amino transferase (ALT), Aspartate amino transferase (AST), Alkaline phosphatase (ALP) by standard methods using enzyme assay kits. Albumin, triglycerides and serum bilirubin were also measured by kits method according to the instructions provided by the company (E–Merck, Germany). The catalase activity was measured according to method of Sinha et al.18 The level of lipid peroxidation in liver homogenate was determined by the method of Buege and Aust.19 Hepatic reduced glutathione (GSH) level was determined by the method of Ellman modified by Jollow et al.20 Liver pieces preserved in 10% formaldehyde solution were used for histopathological study. The liver tissues were placed in plastic cassettes and immersed in neutral buffered formalin for 24 h. The fixed tissues were processed routinely, embedded in paraffin, cut into 4 μm-thick sections and stained with hematoxylin and eosin (H&E). The extent of paracetamol-induced hepatic damage was evaluated by assessing the morphological changes in the liver sections.


Christopher C. Adams, 42, 2621 Sixth Street, Morgan City, LA was arrested on September 1, 2016 at 11:40 am on a warrant for failure to appear for a drug court status conference and failure to comply with the terms and conditions of drug court. Adams turned himself in to a deputy at his residence. Bail is set at $100,000.
Hailey McDaniel, 17, 177 Katy Bridge Approach Road, Franklin, LA was arrested on September 1, 2016 at 1:41 pm for simple battery. A school resource officer was dispatched to a report of a fight at Centerville High School. During the course of the investigation, the SRO collected evidence that McDaniel struck a juvenile female subject during a fight between the two. McDaniel was transported to the parish jail for booking and later released on a $500 bond.
Brandon Davis, 38, 1201 Willow Street, Franklin, LA was arrested on September 1, 2016 at 2:02 pm on a City Court of Franklin warrant for failure to appear on the charges of driving while intoxicated, driving under suspension, and criminal damage to property. A deputy located Davis at a residence on Easy Street in Franklin and transported him to the parish jail for booking. No bail is set.
Joseph Howard, Jr., 44, 1005 West Third Street, Franklin, LA was arrested on September 1, 2016 at 5:15 pm for simple battery. A deputy was dispatched to a complaint of a disturbance in progress on DeForest Brown Lane in Centerville. After arriving at the location, the deputy learned that one of the parties involved, identified as Howard, left the area. A short time later, another deputy located Howard on Third Street in Franklin. During the course of the investigation, the investigating deputy found evidence that Howard punched a male victim in the mouth during an argument between the two. Howard was transported to the parish jail for booking and later released on a $500 bond.
Moses Marks, Jr., 55, 217 Kemper Road, Franklin, LA was arrested on September 1, 2016 at 8:15 pm on a warrant for failure to appear on the charges of driving under suspension and speeding. While booking Marks at the St. Mary Parish Law Enforcement Center, a correctional officer located the warrant for his arrest. No bail is set.
Kennedy Breaux, 50, 109 James Street, Siracusaville, LA was arrested on September 1, 2016 at 8:17 pm on a warrant for probation violation. While booking Breaux at the St. Mary Parish Law Enforcement Center, a correctional officer located the warrant for his arrest. No bail is set.
David Rattray, 55, 1098 Stephensville Road, Stephensville, LA was arrested on September 1, 2016 at 10:13 pm for careless operation of a motor vehicle and operating a vehicle while intoxicated. A deputy was dispatched to a report of a single vehicle crash on Highway 182 in Amelia and saw a vehicle in a ditch. The deputy made contact with the driver, Rattray, and observed that he was swaying from side to side and slurring his words as he spoke. The deputy also smelled the strong odor of an alcoholic beverage on his person. Rattray told the deputy that he missed a turn and drove into the ditch. Rattray was transported to the parish jail for booking. No bail is set.
Detectives of the St. Mary Parish Sheriff's Office Narcotics Section conducted a search warrant at Johnson and Legnon's residence with the assistance of patrol deputies and officers of the Berwick Police Department. Several small children at the residence were released to a family member prior to the investigation. During the course of the search, detectives located marijuana and items of drug related paraphernalia. The residence is located directly across from Berwick Elementary School. Johnson and Legnon were both transported to St. Mary Parish Law Enforcement Center. No bail is set.


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What purpose do hatred and vengeance serve?
by admin|Published March 30, 2019
BY GERRY CHIDIAC
Lessons in Learning
I admit I'm only beginning to understand the concept of forgiveness. But I do know it's a common thread in the lives of the people who I most deeply admire.
I can imagine Nelson Mandela sitting in his tiny prison cell, fighting an internal battle to keep from losing hope. Somehow he came to the realization that hate was futile, that he had to see supporters of apartheid as struggling humans. He came to realize he could understand them and love them if he chose to, and so he was able to forgive them.
After these ideas permeated his spirit, prison walls could no longer hold him.
Mohandas Gandhi also understood that forgiveness isn't a sign of weakness, of compromising or being conquered by another. Forgiveness actually releases us from the bondage of cruelty imposed upon us.
Forgiveness allowed the people of India to say to their British colonizers, "We're not like you, we refuse to embrace hatred and anger, we choose to forgive and thus we're free of your control."
Of course, Mandela and Gandhi had their faults, as did their followers. Perfect humans don't exist, but great humans model ideals that are within the reach of all of us.
After losing most of her family in the Rwandan genocide, Immaculee Ilibagiza met the man who had killed her mother and brother. When this dishevelled man was dragged out of his prison cell and brought before her, all she could say was, "I forgive you."
What purpose would hatred and vengeance serve her?
They wouldn't bring back her family, they would only prevent her from fully living her life.
Filmmaker Tyler Perry stated in an interview how difficult it was to forgive his abusive father. When he did, however, his struggling career as an actor and playwright turned a page. It was as if a cloud lifted. He was finally able to live the life he dreamed and reach millions of people with his art.
Forgiveness, however, is very counter-cultural. We have a justice system designed to extract an eye for an eye, a tooth for a tooth. This isn't to say that a government is not obliged to protect its citizens from unscrupulous corporations and individuals. Laws are necessary, and some people are dangerous and need to be kept away from the rest of society, at least for a time.
But this doesn't mean they can't be forgiven.
What Mandela, Gandhi, Ilibagiza and Perry realized is that those who hurt others live in their own bondage of fear and guilt. Supporters of apartheid in South Africa, for example, lived behind fences. They created their own prisons in their efforts to oppress the rest of the population.
We have all been hurt. We often carry resentments and even hatred for others. Ultimately, however, we need to ask if this attitude serves us.
What would our homes be like if we could look upon our family members as the frail humans they are?
What would our workplaces be like if we could see our bosses and co-workers as people with worries and fears?
What would our societies be like if we saw corporatists as individuals living in terror of losing their material wealth?
What would our governments be like if we saw those individuals with different political views as people who may actually have some good ideas?
What if we could look upon ourselves with the same compassion?
Forgiveness isn't easy but it sets us free, allowing us to live to our true potential.
Great people are great because they model what we can all achieve. Forgiveness is a common denominator among them.
Gerry Chidiac is an award-winning high school teacher specializing in languages, genocide studies and work with at-risk students. Check out his website here. Find him on Facebook. Or on Twitter @GerryChidiac


text:
@interface MPSampleAppTestScenario : KIFTestScenario

+ (id)scenarioToWarmUpAdUnits;

@end

redpajama_set_name: RedPajamaGithub


+ If I find a problem with the system and I need your support, how much time does it take Dhow to resolve it?
Dhow provides a range of options to the client to quickly resolve any problems, and ensure smooth running of the business. The time taken to resolve a problem will depend on various factors such as (Nature of the problem - Support Level agreements in place-Technology enabled at client's location for problem resolution), In today's internet-enabled world, resolving a problem could be as simple as sending an alert to Dhow through email, Skype or messenger service, and trouble-shooting the problem in a matter of minutes.
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A fifth-grade class received an unexpected visitor Thursday. Around noon, a wild turkey crashed into the window of a fifth-grade classroom at the Our Lady of Lourdes School in Utica, N.Y.
A fifth-grade class received an unexpected visitor Thursday.
Around noon, a wild turkey crashed into the window of a fifth-grade classroom at the Our Lady of Lourdes School, said school principal Carol Polito.
Technology teacher Josh Marris was able to coax and walk the turkey out of the building. He said the turkey didn't appear to be hurt, although he did see red on the stairwell when he was taking the bird outside.
"I heard the smash; the fifth-graders screamed," he said. "They went screaming down the hall, some of them were holding the door shut."
He then went in the room and began the process of coaxing the bird out.
"We'll remember this one for a very long time," Polito said.


text:
Home » Case studies» Compensation awarded following hypoxic ischemic brain injury sustained at birth despite brain cooling therapy
Compensation awarded following hypoxic ischemic brain injury sustained at birth despite brain cooling therapy
A claim was made on behalf of our client in relation to brain damage sustained at the time of her birth. Our client's mother suffered a ruptured uterus during delivery and required an emergency caesarean section.
This led to a delay in delivery, and as a result our client suffered a hypoxic ischemic injury which initially left her in a very grave condition. She was subsequently diagnosed with asymmetric dyskinetic cerebral palsy.
Our client was sent for cooling therapy immediately following her birth and her condition started to improve. After many weeks, she was discharged from hospital and proceeded to progress well, reaching many of her developmental milestones. However, at around four years of age, subtle neurological problems started to develop and legal advice was sought.
Following investigation, a letter of claim was sent to the trust and an admission of liability was made. Judgment was entered and substantial interim payments of damages were obtained in order to provide ongoing support and private therapy, as well as to enable the purchase of a suitable house which was subsequently adapted for our client's use.
Settlement of the claim was postponed until we were able to assess our client's future needs. At the stage of the initial investigation, she had difficulties with mobility, using a wheelchair for longer journeys, and she had impairment of fine motor skills, which meant she needed assistance with daily activities such as food preparation and dressing. The decision to delay the final assessment of damages, although frustrating for her parents, proved to be the right course of action as her needs increased over time and difficulties in relation to anxiety and fatigue only became apparent at a later stage.
Settlement took into account lifelong needs and included annual payments for care and case management. A significant lump sum payment was made to cover the costs of therapies, specialist equipment, education, further modifications to her property, deputyship costs and in recognition of lost earnings and pension.
Our client's mother said: "The achievement is quite amazing … thank you so much for all of the work you've done for my daughter, as well as your team. It will make an immeasurable difference to her life."
Partner Stephanie Code led our team advising on this claim, assisted by senior paralegal Aline Constan.
Stephanie Code
Email Stephanie
Aline Constan
Email Aline
Birth injuries and cerebral palsy claims


text:
Q: Extended Desktop to Mac book from Macbook pro I have two Mac one is mac book and other Is Mac book Pro and i am looking for a way so i can use macbook as a extended Monitor for MAc BOok Pro.
is there a way to do it .
thanks in advance

A: It is likely not supported.
This article (apple.com) says how to use an iMac as a second display but makes no mention of using a MacBook(Pro) as one. Which usually means it is not supported.

redpajama_set_name: RedPajamaStackExchange


text:
The Library of Congress > Blogs > Copyright > Find Poetry in Copyright: Joy Harjo
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Find Poetry in Copyright: Joy Harjo
November 29, 2021 by Nicole Lamberson
Poetry is a literary tradition with a long history spanning ancient and even prehistoric times. As did languages and cultures, distinctive forms of poetry developed and evolved around the world, influenced by traditions, histories, cultures, and outside forces.
For Indigenous nations in North America, poetic traditions share common themes but still maintain their unique styles. Existing long before European influences, Native poetry tells each nation's stories, such as those traditions and histories that shaped them, as well as their mythology and spiritual beliefs. As the twenty-third U.S. Poet Laureate Consultant in Poetry Joy Harjo wrote, "The literature of the aboriginal people of North America defines America."
Harjo, who recently began her third term in the role, has learned from and built upon the poetry and storytelling traditions of Indigenous nations. She is an enrolled member of the Muscogee Creek Nation and the author of nine books of poetry. "To her, poems are 'carriers of dreams, knowledge, and wisdom,'" said Librarian of Congress Carla Hayden, "and through them she tells an American story of tradition and loss, reckoning and myth-making."
As the Library's first Native American poet laureate, Harjo launched her signature project, "Living Nations, Living Words," in November 2020. The project highlights and maps the work of contemporary Native poets across the country. She's also the editor of a companion anthology, Living Nations, Living Words: An Anthology of First Peoples Poetry, published in collaboration with the Library of Congress. The "representative offering," Harjo said, showcases "poetry [that] emerges from the soul of a community, the heart and lands of the people."
In addition to writing poetry, Harjo has engaged her creativity and shared her culture through books, plays, and music. She is also an accomplished singer and musician, playing saxophone and flutes, with the Arrow Dynamics Band and, previously, Poetic Justice. A look into the Copyright Office's records shows a variety of registrations dating back to 1976, when Harjo registered her first volume of poetry, The Last Song. Since then, more than a dozen copyright records list Harjo as the copyright claimant.
Copyright registration record for Joy Harjo's first volume of poetry, The Last Song.
Among these creative works are two children's books: The Good Luck Cat, a story of a Native girl and her lucky cat, with illustrations by Paul Lee, and For a Girl Becoming, with illustrations by Mercedes McDonald. In the latter, Harjo explores the journey of a Native girl from birth to adulthood. She later explored her own journey to finding her voice in her first memoir, Crazy Brave, which she registered with the Office in 2012.
Harjo is also the claimant on copyright records for many of her songs and sound recordings, including Native Joy for Real, She Had Some Horses, Witchi Tai To, Winding through the Milky Way, and Red Dreams, A Trail Beyond Tears. Harjo's music, often a blend of blues, jazz, and rock, derives in many ways from traditional Muscogee music and showcases her poetic talents.
You can also find Joy Harjo's poetry in the new Copyright Office exhibit, Find Yourself in Copyright, which features her 2017 book, Conflict Resolution for Holy Beings. The poems in this collection illustrate many poetic forms—including lyric, freeform, and prose—and explore the struggles of the Indigenous people and the hope that endures for all. She writes:
We will all make it through,
despite politics and wars, despite failures
and misunderstandings. There is only love.
Find Yourself in Copyright explores how U.S. copyright law has evolved and how the millions of copyright claims registered with the Office illustrate the varied nature of original works. Once the Library of Congress's Madison Building fully opens to the public, you can visit the exhibit on the fourth floor. In the meantime, you can explore the exhibit's companion website.
Posted in: copyright, engage your creativity, Find Yourself in Copyright, Native Americans, Poetry, Uncategorized
This blog is governed by the general rules of respectful civil discourse. You are fully responsible for everything that you post. The content of all comments is released into the public domain unless clearly stated otherwise. Your submission may be subject to disclosure under the Freedom of Information Act (FOIA). The Library of Congress does not control the content posted. Nevertheless, the Library of Congress may monitor any user-generated content as it chooses and reserves the right to remove content for any reason whatever, without consent. Gratuitous links to sites are viewed as spam and may result in removed comments. We further reserve the right, in our sole discretion, to remove a user's privilege to post content on the Library site. Read our Comment and Posting Policy.
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