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Lack of awareness about autoimmune hepatitis
By Mindo - 03rd Jan 2020 | 16 views
Autoimmune hepatitis diagnosis. Anatomical 3D model of human liver is near stethoscope, results of laboratory tests of liver function and printed on notepad diagnosis of Autoimmune hepatitis
Autoimmune hepatitis (AIH) is on the rise but remains under-diagnosed and under-recognised, the 2019 ISG Winter Meeting heard
Irish-born AIH expert Prof Dermot Gleeson, Professor of Hepatology at Sheffield Teaching Hospitals, UK, gave a tour de force update on AIH, a corticosteroid-responsive liver disease arising consequent to immunogenetic and environmental risk factors, which can be difficult to correctly diagnose and treat.
"AIH is still in the 20th Century in terms of treatment and randomised controlled trials," he commented.
Core diagnostic AIH features include the patient having an 'active' hepatitis, negative virology, typically a raised globulin or IgG, antibody titers, and a high incidence of rosettes and emperipolesis in histology. It "is a disease of women" and has a peak of around 60 years, not younger as previously believed, Prof Gleeson said.
Misdiagnosis/under-diagnosis is common, especially with the simplified AIH diagnostic criteria.
"We miss about 30-to-40 per cent of probable AIH by the more expansive 1999 criteria, and this is steroid-responsive disease," he said.
Prof Gleeson stated it is accepted that a diagnostic biopsy is generally needed. Differential diagnoses include Wilson's disease, hepatitis E, and non-alcoholic fatty liver disease or drug-induced liver injury. If uncertainty still exists around the diagnosis of AIH, Prof Gleeson recommended excluding all viruses and precipitants, checking soluble liver antigen antibody, HLA type, and carrying out a steroid trial; "if there is no response, then AIH is less likely".
AIH is on the rise, but remains under-recognised, according to Prof Gleeson.
"This disease is becoming commoner," he said.
"The prevalence is about 23 per 100,000, which means that if you have a catchment area of 250,000, you should have 60 patients. If you have a lot less than that, you'd have to wonder if you are under-diagnosing AIH."
Quoting familial risk data on AIH, he said, while there is an increased genetic risk, it is still quite small overall.
"The absolute risk is very low… even for a twin, the absolute risk is one-in-77," Prof Gleeson said.
The clinical course of AIH reflects relapsing and remitting, hepatocyte-targeted immunologic damage, which is countered by reparative responses to cell injury, with cirrhosis occurring in 12-to-20 per cent of patients at 10 years. Appropriate and timely immunosuppressive therapy can drive the disease into remission, albeit with inevitable side-effects, and relapse is frequent (50-to-70 per cent in one year if treatment is stopped). "It sums everything up with regards to AIH that we are still basing standard treatment on a trial published almost 50 years ago — a Mayo Clinic study that showed high-dose prednisolone or combination lower-dose prednisolone plus azathioprine led to higher clinical, biochemical and histological remission rates compared to azathioprine or placebo. Importantly, there was no difference between azathioprine or placebo, so azathioprine as an induction treatment is useless. It's fine for maintenance, but it is useless on its own to induce remission."
While steroids are generally very necessary, Prof Gleeson also cautioned about dosages and side-effect risks, including diabetes development and higher mortality rates, "so please be careful with high-dose steroids". For AIH patients who are intolerant of steroids, budesonide is the standard choice, "though it is not to be used in cirrhosis", while for those intolerant of azathioprine, mycophenolate (though not in pregnancy) can be used, he said. Tacrolimus also has good results as a second-line drug.
Summarising what is needed to improve outcomes in AIH, Prof Gleeson said dedicated consultants and more specialist nurse involvement are needed, as are better short-term surrogate markers of outcomes, non-invasive fibrosis monitoring, a better focus on patient perspectives, more audit, and cancer screening and vascular risk factor stratifying.
Speaking to the Medical Independent, Prof Gleeson said doctors "need to listen to AIH patients more".
"These people have a bad quality-of-life. They take these drugs that give them side-effects and I don't think we have paid enough attention to that. There has been a kind of complacency about treatment of AIH over the last seven decades really, since the advances of the 1970s, and it has been kind of static since then.
"There are various reasons why it has been difficult to develop drugs and to compare them — we lack markers of outcomes. It is only in the last decade that we have realised that the outcome isn't actually as good as we thought… "
He agreed that there is not enough attention and awareness about AIH compared to hepatitis C, and that compared to 25 years ago, "now AIH is the worse one to get."
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This year, WH is launching Chase The Sun, an early morning weekend workout dedicated to mindfulness, stretching, toning and letting go in the outdoors. The programme will start just before sunrise with an empowering, body positive stretching and relaxation exercise, followed by a sunrise Pilates and body conditioning movement session, wrapped up with an energising dance workout, all set against the majestic backdrop of Val de Vie Estate. After working and warming our bodies, we'll serve refreshments and treats and then roll into the rest of a beautiful weekend. With Mother's Day, the day after Chase The Sun, we'll be encouraging mom-and-daughter tickets and bestie tickets and we'll also include ticket packages that include luxurious overnight accommodation at the estate.


The most common local resident on Long Caye is the hermit crab. They are terrestrial crabs that inhabit the island by the thousands, and although nocturnal they are encountered at all hours of the day, everywhere. Most of these hermit crabs inhabit the shells of the West Indian Top Snail (Cittarium pica), a large snail found in the inter-tidal zone on the shores of the island. Hermit crabs are seen in all stages of growth, from miniscule juveniles to giants that are several inches across. They crawl along endlessly, hardly ever stopping, scavenging for food. Their tracks are seen in the sand everywhere, with the shells leaving drag marks.
Hermit crabs have a very effective defense system. If threatened they retract inside their shell and present a sealed, armored body, barely protruding from the opening, with only their formidable claws exposed and ready to snap at anything nearby. One has to be careful when handling these crabs, since their incredibly strong claws can easily cut through a finger.
As a hermit crab grows, it needs to find a new shell to accommodate its bigger body. However, since they don't make their own shell, they have to find a new one. There are almost no empty shells lying around, virtually every shell on the island is already taken (and we occasionally find crabs in other homes, such as shampoo bottles, small light bulbs, champagne corks, and other odd trash). So when new shells are needed, the crabs will select one unlucky, large, individual and gang up on him. Working together the smaller crabs extricate him from his shell and leave him unprotected. This frees up a large shell and the victim soon dies. Once that shell is free, all the other crabs in the group move up to a larger shell, leaving only the smallest one free which is quickly occupied by another crab not originally in on the exchange. We often see these 'gangs' of crabs in small heaps, going through this process.
Hermit crabs serve an important function on the island; they compost all of our kitchen scraps for us. All food scraps are taken to the island dump and piled in a huge mound. This pile could take over the island if it weren't for the crabs turning them to dirt, little-by-little. Also at night the crabs do a "patrol" of our dining hall floor, and leave it completely clean for the next day. If you are up early, you will see their tracks all over this sand floor.
Every Friday night we host a Hermit Crab Race, a great way to end a fantastic week. This event is hugely popular, you will be amazed to see the excitement this generates!


Maintenance kit with fuser core exchange. PrinterTechs Long Life remanufactured fuser, HP M601, M602, M603.
Maintenance kit with fuser core exchange. PrinterTechs NEW fuser, HP M601, M602, M603.
Maintenance kit, no fuser core exchange. PrinterTechs NEW fuser, HP M601, M602, M603.
PrinterTechs is proud to introduce our Long Life M601 M602 M603 series fusers. We have tested our Long Life fusers to over 500,000 pages, try doing that with a competitors' fuser! That's double the life expectancy of a new Genuine HP fuser. We have two types of fusers: the Long Life remanufactured fusers and the new fusers (standard life, rated at 225,000 pages). Our Long Life remanufactured fusers are remanufactured by us, right here in Middleton, WI --- not Mexico or China, like many of our competitors' fusers. We control the quality by using our own experienced technicians and our own long life parts.
If you are a service company utilizing the cost-per-print model or managed print, give us a call. Our fusers and maintenance kits will save you on service calls and maintenance costs because of their reliability and longevity.


Atlanta home builder, than look no farther than Traton Homes. The numbers are in and the metro area builder once again made the Atlanta Business Chronicle's list of the Top 15 Home Builders in Atlanta. In fact, they were the highest ranking local builder on the list, coming in at No. 6!
However, this isn't the first time that the builder was recognized for their outstanding homes and customer service. In addition to being consistently ranked on the Atlanta Business Chronicle's list, Traton Homes is a five-time recipient of the GuildMaster Award for excellence in customer service and has received several gold and silver OBIE awards from the Greater Atlanta Home Builders Association.
Traton Homes can be found building new homes priced from the $180,000s to the $700,000s in more than 15 communities throughout the metro Atlanta area. The locally owned home builder celebrated their 41st anniversary this summer, and they are still going strong with new communities opening every year. In fact, Traton Homes recently announced that they will soon begin building new homes priced from the low-$800,000s in the amazing coastal community, Frederica, located on St. Simons Island!
Traton Homes is known throughout metro Atlanta for providing buyers with an 'Altogether More' experience.


Take a look inside this structure here on Hidden City Philadelphia.
This photo, taken a block south and dated 1901, shows "CUMMINGS COAL" emblazoned on the railroad viaduct overpass. Unfortunately it is too far away to see the structures.
Here is the location in a photo dated 8/15/1894. The buildings are different (all of them gone at this point), suggesting this remaining structure was built later.
PhillyHistory.org. Philadelphia Department of Records. 8 April 2008. <http://www.phillyhistory.org>.
exceptionally cool and inventive site!
The picture does not match the building.
Regardless is a beautiful building dating back to 1840.
Was a two story building by 1867. Please see map/link below.


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Win The Jetsons Meet The Flintstones on DVD (Ended)
It was an event that cartoon fans had been fantasizing for years. In 1987, many years after the cancellation of both The Flintstones and The Jetsons, this TV movie was released as part of the Hanna-Barbera Superstars 10 — a group of 10 animated movies that were created for syndication. Though the two animated series were often compared to one another, it was the first meeting of the space-age and stone-age families. Many of the original voice actors returned to perform their trademark characters.
In the movie, Fred Flintstone (Henry Corden) and Barney Rubble (Mel Blanc) are fired from their jobs at the quarry and are afraid to tell their wives. In the future, George Jetson (George O'Hanlon) is having work issues of his own with Mr. Spacely (Mel Blanc). To escape his problems, George takes his family on a little vacation, courtesy of son Elroy (Daws Butler) and his experimental time machine. When the invention malfunctions, the Flintstones and Rubbles are sent to the future and the Jetsons are left stranded in the past. Will the stone-age and the space-age ever be the same again?
Though The Jetsons Meet The Flintstones has been released on VHS tape a few times over the years, it was never released on DVD until now. The animated movie is available from the Warner Archive Collection and can be purchased for $14.95 directly from the studio or for $17.99 from Amazon.
You can also try to win a copy here. To enter, you need to merely post a comment below.You can enter once per day.
If you'd like an additional chance to win, leave a comment on our Facebook page under the wall post about the contest. You can enter once per day.
You can also follow us on Twitter and tweet "@tvseriesfinale Hope I win the Jetsons & Flintstones on DVD! https://tvseriesfinale.com/?p=19725". You can enter once per day.
If you don't have Facebook or Twitter accounts, you can email us as another way to enter.
Guidelines: This giveaway is open to participants with a United States mailing address only. (International readers can enter if they have a friend in the States who can accept their prizes by mail.) Many may enter but one person will win. You must be 18 and older to enter and no purchase is necessary. Contest ends June 29, 2011.
UPDATE: Congratulations to Jasonz who won this DVD set in our contest. Thanks to everyone who played and we've got more contests coming!
More about: The Flintstones, The Jetsons, The Jetsons (1985)
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I love the jetsons meet the Flintstones! I have been watching it since I was a kid! I watch it every time its on tv! I have it recorded on a tape & have shown it to my younger niece & nephew & they love it as well!
I loved both shows and loved the movies!

redpajama_set_name: RedPajamaCommonCrawl


All original, collectible and accessible. 3 days of art, hundreds of New Zealand artists and thousands of artworks. All under one roof in a dynamic and inspiring environment. Experience the wealth of artistic talent from around New Zealand Artwork from new and emerging artists alongside more established artists.


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Marc Ballanfat est un professeur de philosophie, traducteur depuis le sanskrit et spécialiste des philosophes de l'Inde ancienne.
Il a enseigné pendant quinze années la philosophie à Aubervilliers. De 2011 à 2020, il a enseigné en Classes préparatoires aux Grandes Écoles au Lycée Alexandre Dumas (Saint-Cloud). Il est aussi chargé de cours à l'université Paris-IV Sorbonne.

Il est agrégé de philosophie, et docteur en philosophie (1986) et en histoire des religions.

Biographie

Alors étudiant en licence de philosophie, Marc Ballanfat entreprend un voyage en Inde et s'imprègne de la culture indienne. De retour en France, il suit des cours de sanskrit de François Grimal.

De 2001 à 2007 il est directeur de programme au Collège international de philosophie.

En 2007, il traduit et commente la Bhagavadgita, publiée dans la collection Garnier Flammarion.

En 2011, dans Simone Weil ou Le combat de l'ange contre la force il fait le rapprochement entre la pensée de Simone Weil et la mystique hindouiste. Il retrace l'ensemble du parcours de Simone Weil autour de la notion de force.

En 2016, il s'associe avec Amina Taha-Hussein Okada et publie l'ouvrage illustré La Bhagavadgita illustrée par la peinture indienne aux éditions Diane de Sellier.

Publications

Ouvrages
 Bouddha autobiographies, éditions Berg International, 1998
 La métaphysique, Paris, éditions Ellipses, 1999
 Les matérialistes dans l'Inde ancienne, Paris, éditions L'harmattan, 2000
 Introduction aux philosophies de l'Inde, Paris, éditions Ellipses, 2002
 Vocabulaire des philosophies de l'Inde, Paris, éditions Ellipses, 2003
 La Bhagavadgita, coll. « Texte intégral »,  Garnier-Flammarion, 2007
 Philosophies d'ailleurs - tome 1, Les pensées indiennes, chinoises et tibétaines, éditions Hermann, Paris, 2009
 Simone Weil ou Le combat de l'ange contre la force, Paris, éditions Hermann, 2011
 Introduction aux philosophies de l'Inde, Paris, éditions Ellipses, 2017

Participations à des ouvrages collectifs
 Comment gagner des points au bac L, éditions Studyrama Eds, 2004
 Comment gagner des points au bac ES, éditions Studyrama Eds, 2004
 Réussir ses plans de dissertation, éditions Studyrama Eds, 2005
 Rue Descartes, n° 54 : Les rationalités de l'Inde, éditions PUF, 2006
 Savoir problématiser : Comprendre et analyser un sujet, éditions Studyrama Eds, 2009
 Revue Française de Yoga, n° 41 : La dynamique du désir, 2010
 Argumenter et analyser un problème, Studyrama Eds, 2011
 La Bhagavadgita illustrée par la peinture indienne (avec Amina Taha-Hussein Okada), éditions Diane de Sellier, 2016
 Gestion des conflits et coopérations en Europe. Enjeux et représentations du  à nos jours, L'harmattan, 2017
 L'Un dans l'autre : De l'unité des spiritualités, L'harmattan, 2017

Notes et références

Liens externes

Traducteur depuis le sanskrit vers le français

redpajama_set_name: RedPajamaWikipedia


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Microsoft Research Opens a Lab in New York City
– May 2, 2012 – In the two decades since the formation of Microsoft Research, the organization has grown from its beginnings on Microsoft's corporate headquarters in Redmond, Wash., into a global research force with 12 labs across four continents — all devoted to advancing the state of the art in computing research and contributing cutting-edge advancements to Microsoft products.
Jennifer Chayes
Jennifer Chayes will now be managing director of both Microsoft Research New England, which she founded in July 2008, and Microsoft Research New York City.
Beginning May 3, that lab count increases to 13 with the creation of Microsoft Research New York City.
"The addition of Microsoft Research New York City reflects the company's long-term investment in basic research," said Rick Rashid, Microsoft chief research officer and head of Microsoft Research. "In concert with Microsoft's product groups, Microsoft Research guides and influences the company's pursuit of applying transformative technologies and new technology trends to its products and services."
The new lab, to be based in Manhattan, will be led by Jennifer Chayes, who becomes the managing director of both Microsoft Research New England, which she founded in July 2008, and Microsoft Research New York City.
"The Microsoft Research New York City lab reflects an opportunity for Microsoft Research researchers and developers worldwide," Chayes said, "to interact deeply with the vibrant academic and tech communities in the New York metropolitan area, as well as an opportunity to attract great new talent to Microsoft."
Fifteen world-class researchers form the lab's initial team, including three founding members, each of whom is a leader in fields of vital importance to Microsoft Research and brings strong ties to the academic community of the New York metropolitan area:
David Pennock, who conducts research at the intersection of computer science and economics, is past chair of the Association for Computing Machinery's Special Interest Group on Electronic Commerce, the academic organization dedicated to topics in that area. Pennock will serve as assistant managing director of the new lab.
Duncan Watts, a former full professor of sociology at Columbia University and a pioneer of modern network science, focuses on computational and experimental social science. He is the author of three books, including "Six Degrees: The Science of a Connected Age" and, most recently, "Everything Is Obvious*: Once You Know the Answer."
John Langford, whose interests are in scalable interactive machine learning, learning reductions, and other irresistible research topics, is the program co-chair for this year's International Conference on Machine Learning.
The three, each of whom previously worked for Yahoo! Research, represent Microsoft Research's ongoing ability to attract the best and brightest researchers, and their particular strengths underscore the close alignment between the New York City and New England labs.
David Pennock
David Pennock will serve as assistant managing director of the new lab.
Microsoft Research New England has developed a reputation for being rich in interdisciplinary research, and it pursues work in social media, empirical economics, and machine learning, in addition to theoretical computer science, cryptography, and mathematics.
The New York City lab will investigate complementary research areas: computational and experimental social science, algorithmic economics, and machine learning, along with information retrieval. The close collaboration of the two labs, and their interaction with the rest of Microsoft Research, is designed to extend state-of-the-art work in these key areas.
The new researchers will engage in large-scale machine learning, prediction, and online-market design. They also will develop new techniques in the fields of both computational and online experimental social science.
Their research will help to shape the technology of the future, and they all expressed an eagerness to embrace their new roles.
"It's an incredible opportunity," Pennock said. "We get to start a new branch of Microsoft Research, which is the best place in the world to do research. It's a chance to work with some great people in the New England lab and throughout Microsoft Research and Microsoft. It's an incredible time for Microsoft, and we are looking forward to doing great research and having great product impact within the company."
Pennock added that the new lab will be able to plug into a thriving New York tech ecosystem.
"In addition to growing our already strong ties to the academic research community," he said, "we'd like to play our part in the New York City tech scene, including the startup, venture-capitalist, and hack/make communities, plus the new Cornell-Technion campus, contributing what we can to Mayor Michael Bloomberg's vision of New York City as a tech hub."
Watts has a similar goal.
Duncan Watts
Duncan Watts, a former full professor of sociology at Columbia University and a pioneer of modern network science, focuses on computational and experimental social science.
"My ambition for the New York City lab is that it will become a leading center, if not the leading center, for computational and experimental social science," he said, "leveraging the intellectual capital of the New York City academic community, the tremendous data assets of Microsoft and Microsoft's partners, and the rapidly growing local tech scene.
"The scope of what we can do here is incredible, and the support we have received already from the Microsoft Research community is both gratifying and impressive."
Langford relishes the opportunities afforded by Microsoft Research's position in the research community.
"Machine learning is shifting from an academic discipline to an industrial tool," he observed. "In the process, many new research problems are being discovered, shifting the center of gravity of research to a place between industry and academia, exactly where Microsoft Research lies.
"The sheer scale of Microsoft also implies that successful research can be used many times across the company. It's always fun to have deployed systems to brag about, and the more, the merrier."
In addition to Pennock, Watts, and Langford, the group of founding members of the New York City lab includes Dan Goldstein and Siddharth Suri, experts in experimental and behavioral social science; Sharad Goel and Jake Hofman, experts in computational social science; and David Rothschild, an expert in economics and prediction markets.
A key part of Microsoft Research's mission is to give Microsoft the agility to respond immediately when the world changes — or to change the world itself. The new researchers at Microsoft Research New York City found that allure impossible to resist. Langford cited four reasons why:
"Microsoft moved very fast in making decisions, and I sincerely appreciate the agility."
"Microsoft has simultaneously become a more open and competitive company, including, in my case, support for Vowpal Wabbit."
"Microsoft Research has a strong tradition of support for basic research, which I greatly value."
"A combination of outstanding and unique opportunities for future collaborations yielding products and research."
For Watts, it was the whole package that tipped the scale.
John Langford
"Microsoft Research is a world-class research organization with a long history and a deeply rooted culture of appreciation for both basic and applied science," he said. "The opportunity to found a new Microsoft Research lab is one that comes along only rarely, and the chance to do it in such a great city as New York is, for me personally, even more special and exciting. It really feels like a once-in-a-career opportunity."
Pennock actually has firsthand experience at Microsoft Research, having interned at the Redmond lab in 1998 under Eric Horvitz, now a Microsoft distinguished scientist and deputy managing director of Microsoft Research Redmond. Over the years, Pennock has maintained professional relationships with Microsoft Research colleagues such as Horvitz, Chris Meek, Moshe Babaioff, and Moshe Tennenholtz. But it was Chayes who, for him, proved convincing.
"The one thing that really sealed the deal for me was Jennifer," Pennock said, "and the opportunity to work for her, not just by reputation but by her actions.
"The other thing is that Microsoft Research New England has a lot of the same ideals. It's an interdisciplinary group, and that's exactly the kind of work I do, at the intersection between computer science and economics. Duncan works at the intersection of computer science and sociology. We are, by nature, interdisciplinary, and that's exactly what we see at Microsoft Research New England. They have economists. They have computer scientists and sociologists. It's just a natural fit."
Pennock stressed that Microsoft Research New York City will have a wealth of leadership at its disposal as it begins to carve out its own particular niche.
"Duncan and John are great leaders," he said, "and Jennifer and Christian Borgs [deputy managing director of Microsoft Research New England] are, as well. We'll all be working together in a consensus style to run the new lab."
His initial plans include diving into research, beginning to attract a stream of world-class visitors from academia, and building relationships within Microsoft.
"One thing we're going to do right away is visit Redmond and get to know the product groups," Pennock said. "We'll be working a lot with the Online Services Division, so we want to meet those folks. We'll also be talking to people in the Server and Tools Business. We want to make sure we are looped into the company and thinking about Microsoft products from Bing to Xbox to servers to … everything."
That sort of passion bodes well for the newest member of the Microsoft Research constellation. For more enthusiasm, read That sort of passion bodes well for the newest member of the Microsoft Research constellation. For more enthusiasm, read Chayes' blog post about the creation of Microsoft Research New York City.


text:
package org.pentaho.di.job.entry;

public interface JobEntryRunConfigurableInterface {

  String getRunConfiguration();

  void setRunConfiguration( String runConfiguration );

  void setRemoteSlaveServerName( String remoteSlaveServerName );

  void setLoggingRemoteWork( boolean loggingRemoteWork );

  void setChanged();

}

redpajama_set_name: RedPajamaGithub


On Friday we are heading away on a wee holiday, some real relax time before I start back at work the start of September.
So again it's up to me..
Mmm fudgie brownies is what I have a hankering for but alas no dark chocolate in the house- for a change! Typical!
We do however have white chocolate- of which I am not the biggest fan- too sweet… unless… its mixed with peanut butter… Light bulb moment!
As easy as mixing everything together, putting into a lined 8″ square tray, smoothing out and baking.
I melted about 100g of White Chocolate and mixed in 2Tbs Peanut Butter and smeared this over the brownie- yum.


Cale and Kirsten held their intimate wedding with their immediate families and closest friends on the balcony at the Lethbridge Lodge, which provided a beautiful start to the day!
Instead of letting the rainy day get them down, Cale and Kirsten were great sports and super easy going, not minding going out in the rain one bit! We equipped them with umbrellas after our indoor photos at the Lodge and Casa and made use of the lush green colors the weather gave us for their spring wedding photos.
Amelia and Abram chose early May for their Lethbridge spring wedding and we had a beautiful day with sunshine and all of the new leaves starting to peak out.
I mentioned before how Abram hates having his photo taken, but you could tell he was so smitten by Amelia because he was grinning all day… he probably forget we were taking his photo ;) Amelia was full of huge laughter around him and their families, and she looked so stunning.
They chose the Lethbridge Lodge as their main location both for getting ready and their reception, so it was a natural fit to do many of the portraits there as well. After photos were finished, we headed over to the beautiful Nobleford Christian Reformed Church for their sweet and thoughtful ceremony.
What happens when you combine kilts, light sabers, and a Buddhist temple? Trent and Veronica's wedding! The two of them planned such a fun little wedding that perfectly showed off their unique personalities (including many references to Trent's geeky interests – that's why I'm friends with him, after all!). They are so adorable, and the love between them so obvious (especially in Veronica's beaming smile all day).
After their ceremony at the Lethbridge Buddhist Temple (where they exited under light sabers, of course!), they danced all night with their family at the Lethbridge Lodge – first with their choreographed dance they took lessons for, and then to the live music of Bandemonium.


Ways to take Amla for Diabetes � Take 2-3 gooseberries and discard their seeds. Now grind the amla to get a fine paste. Either using a fine cloth or a sieve, squeeze out the juice from this amla paste.... 17/04/2017�� Karela powder is very good for health, and it is very easy to make it and store it for a long time. this powder you can serve with fresh hot rice by adding little ghee.
To medfree Is jamun powder & karela powder helps in controlling type-2 diabetic ?.mention the complete LCHF lunch & dinner please. diabeticsab � 5 years ago � 15 Replies. you are mentioning only eggs,tamotos,cheese, cucumber in LCHF diet.You dont take rice or roti? Is the same menu for the whole year. Reply Like (0) Follow post. 15 Replies. oldest � newest. shrisamarth. Volunteer. 5 how to take selfies like kendall jenner 17/04/2017�� Karela powder is very good for health, and it is very easy to make it and store it for a long time. this powder you can serve with fresh hot rice by adding little ghee.
Take 1/4 to 1/2 teaspoon up to three times daily or as recommended. The bitter gourds that are firm and green in colour should be preferred while those with orange spots should be ignored.
Being multi-purpose in nature, bitter gourd is used in multiple ways. Some of them are listed below-Bitter gourd is used to prepare one of the tasty dry/curry item called �Bharwan karela� or �Stuffed bitter gourd�.


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Announcing Atlas Network's 2023 Smart Bets
One of the most exciting opportunities from Atlas Network is our Smart Bets program, which exemplifies all three components of our Coach, Compete, Celebrate strategic model. The 2023 Smart Bets class represents 10 partners in our network who have been selected for going above and beyond in their work to generate positive change in their communities. Grantees will be awarded an initial $25,000 grant, which includes a matching grant offer of $10,000. They will also compete for an additional $50,000 grand prize at the Liberty Investors Summit, held during the Liberty Forum & Freedom Dinner 2022 in New York City, with two runner-up prizes of $25,000. Membership in the 2023 Smart Bets class will also provide grantees with the opportunity to work closely with the Atlas Network team and past and present Smart Bets organizations in the form of consultations, collaborative meetings, and engagements with prospective donors. Finally, the partners from the Smart Bets class will be eligible for a $25,000 prize that is awarded to the grantee that achieves the greatest impact over the course of a year.
Without further ado, read on to learn more about Atlas Network 2023 Smart Bets class!
Bikalpa – an Alternative | Nepal
Countering Populism, Promoting Freedom
The majority of political parties in Nepal are left-leaning, with many policy makers and government authorities subscribing to populist ideologies. The media has likewise been criticized for politicization and bias, with populist news dominating the headlines. Without a diversity of options for receiving news, this system creates an environment where populism and nationalism become the predominant political ideology shaping the average Nepalese perspective. Bikalpa – an Alternative saw the need for a neutral news source that would provide an alternate discourse and promote the values of freedom and democracy in Nepal, and thus started a news portal to do just that called Bikalpa Khabar.
Centre for Development and Enterprises Great Lakes | Burundi
HARAGEZE
Street trading is the main source of income for over half (57%) of the Burundian population, as an accessible, low-cost entrepreneurial opportunity, but it is also an occupation which leaves individuals with few economic and property rights. Street traders operate at risk of abuse by municipal authorities, including threat of eviction, seizure of agricultural assets, and arbitrary fines. In effort to address this reality, the Centre for Development and Enterprises Great Lakes launched "Harageze" (translated to it is time), a project that seeks to reform street trade laws as a means of promoting economic progress in Burundi.
Fundacja Liberté! | Poland
Freedom Games
In a world that is becoming increasingly interconnected and facing populist and illiberal tendencies, Fundacja Liberté! sees not only potential but a need for creating spaces for interdisciplinary and cross-cultural conversation and debate to promote liberty, democracy, free markets, and open society. This is why they created Freedom Games, a forum based in Poland that aims to offer a creative and engaging space for individuals from sectors of culture, business, and public affairs (among others) to challenge and inspire one another in a network-building space. Not only does the event bring together leading intellectuals and decision-makers from around the world, but it also engages over 1 million viewers online.
Fundación para el Avance de la Libertad | Spain
Taxes Down, Citizens Up!
In Spain, the national, regional, and municipal levels of government overlap in different areas, while still each requiring a significant budget, incurring high taxes for citizens. With the current climate of high inflation and significant economic stress for citizens, there has been increasing social demand for more government austerity and less non-essential expenditures. The Fundación para el Avance de la Libertad (FundaLib) works to contribute to tax policy reform, and so far has seen victory with 25 improvements in tax law. A central component to this work is FundaLib's annual production of the Regional Tax Competitiveness Index and the Index for Economic Freedom.
Frontier Institute | United States
Big Sky, Big Opportunity
Elections are forecasted to deliver Republicans a supermajority for the 2025 legislature in Montana, opening the possibility for constitutional revisions for powerful policy reforms. Frontier Institute aims to shape the policy agenda for this supermajority with an expansion of their policy capabilities by launching the Center for New Frontiers. The Center will be dedicated to opening new opportunities for freedom and innovation in Montana, with primary policy aims including constitutional reforms to encourage economic dynamism, establishing permanent red tape reduction measures, enabling cryptocurrency and blockchain innovation, eliminating policy barriers to energy abundance, and developing human-first environmental policy.
John Locke Foundation | United States
Empowering North Carolinians to Escape Poverty Project
We measure poverty rates in percentage points, but the people behind those statistics have a common desire: freedom to pursue a better life. That means breaking the cycle of poverty, providing for their families, and reducing dependence on government. Government intervention has made the vicious cycle of poverty even more difficult to escape. The John Locke Foundation's Empowering North Carolinians to Escape Poverty project is tackling the leading causes of poverty in North Carolina and beyond, including economic opportunity, overcriminalization, affordable housing, energy affordability, and mental health and substance abuse. The research and policy recommendations from this project stand to be transformative in changing the conversation around poverty alleviation policy from "What can government do to help?" to "How can government remove barriers so men and women can pursue economic independence?"
Lithuanian Free Market Institute | Lithuania
Economics, Civics, and Liberty for Early Teenage Learners
Neuroscience and psychology show us that the early teenage years are a crucial time for shaping an individual's social and civic attitudes and beliefs. Lithuanian Free Market Institute aims to embrace this stage of development to foster value-based economic and civic learning that is grounded in the ideas of liberty and agency-based social skills. Lithuanian Free Market Institute has created an interdisciplinary course which currently reaches six in ten high school students in Lithuania, and marries together the ideas of citizenship and sound economic reasoning, and economics and ethics.
New Zealand Taxpayers' Union | New Zealand
Leading the World from the Bottom of the World
In the 1980s, New Zealand's economic reform and deregulation set a precedent that would eventually lead to Reagan/Thatcher-style liberalism spreading throughout the West. New Zealand Taxpayers' Union hopes to work to reestablish New Zealand as a leader of freedom and become the most popularly supported taxpayer groups in the world. They aim to take advantage of the upcoming general election and subsequent new government in New Zealand and formulate policy platforms that focus on improving New Zealand's overall economic freedom.
Students for Liberty Brasil | Brazil
LibertyLab
Within Brazilian public schools and universities, students have few opportunities to learn about liberty, due to an emphasis on collectivism and the importance of government, and they lack learning opportunities presented from the perspective of free-market policies and entrepreneurship. Students for Liberty Brasil (SFLB) aims to change this reality by reaching students throughout Brazil and instilling the values of liberty and entrepreneurship. SFLB's approach is two-fold. Within a decade of its existence, several organizations have sprouted from SFLB and now operate to directly impact public policy. SFLB now turns its attention more directly toward students, offering courses and trainings to foster a commitment to liberty and prosperity that will make students today the pro-liberty leaders of the next generation.
Young Voices | United States
Young Voices Level Up Initiative
Talent development, particularly of young people who can appeal to and engage with other young people, is a massively overlooked component of any sustainable political movement. Young Voices recognized this, and over the past decade has worked with over 400 rising libertarian leaders in industries ranging from think tanks to media. Young Voices is becoming the premier talent pipeline in the liberty movement, and their work centers on three primary programs: the Regional Leaders Program, the Accelerator Program, and the Dissident Project.
Keep an eye on our Atlas Network blog in coming weeks for more information on each of these organizations.


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Le mot singulier (du latin ) peut être employé comme :
 adjectif
 pour désigner quelqu'un ou quelque chose d'unique
 en mathématiques, un point singulier
 nom commun, pour désigner :
 le nombre grammatical en général
 le singulier d'un mot en particulier

 Singulier est une compilation du chanteur français Jean-Jacques Goldman

Voir aussi


Implementing Emotional Support services and programs requires a team focused, multidisciplinary approach. This session will introduce participants to a self-assessment tool titled, Quality Indicators of Emotional Support Services and Programs(QIESSP), that will support LEAS in implementing evidence-based Emotional Support services and programs. Participants attending this session will examine the features of the QIESSP document, consider ways in which to build or strengthen their services and programs and discuss the alignment of the QIESSP tool to the Charlotte Danielson Framework for Teaching.


Welcome to the world of professional, personal care customized for your individual needs. As a licensed Aesthetician and Manicurist, Teko shares nearly 40 years of knowledge with each client to create a special experience.
Teko offers treatments for addressing expression aging, the appearance of fine lines and wrinkles, as well as for hydration and improving the skin's circulation. These services include custom designed facials, microcurrent and LED phototherapy anti-aging treatments, detoxifying face and body treatments, waxing, personalized make-up lessons, and corrective pigmentation treatments for face, neck, décolleté and hands.


"The Visit" is the latest horror film to hit our screens and whilst it isn't perfect, it definitely offers some real scares. On the surface this film has two major issues; the first is that it utilises a found footage format which audiences are becoming increasingly frustrated with, and the second is that it was written and directed by M. Night Shyamalan. However, these issues fade away as the film hits its halfway point, with endearing and off-kilter performances capturing the audience's attention, and the found footage format used to facilitate genuine character development rather than simple jump scares.
Personally, I think that Shyamalan gets a rough time of it from critics, because although he's made some awful movies he's also responsible for some real gems. His filmography is one of inconsistency rather than incapability, a mixed bag with "The Sixth Sense" and "After Earth" acting as two ends of a very strange spectrum. It's crazy that the same person is responsible for both, but at the end of the day every director has one or two bad films on their resume. Here Shyamalan is at his brilliant best, returning to the genre that made him famous – psychological horror.
"The Visit" is about two children, Becca (Olivia DeJonge) and Tyler (Ed Oxenbould), as they visit their grandparents, Nana (Deanna Dunagan) and Pop Pop (Peter McRobbie), for the first time. Initially the pair warm to their grandparents and everyone gets along, even though Nana and Pop Pop are a little odd, but things take a disturbing turn when Becca breaks the 9:30pm curfew set by Pop Pop. From there things only get more unsettling and the film begins to whittle away at the audience's nerves with each night that passes.
The reason that found footage comes into play is that Becca is an aspiring filmmaker, who sets out at the start of the film with the goal of making a documentary for her mother, played by Kathryn Hahn, to earn her forgiveness from Nana and Pop Pop for an event which happened fifteen years ago. It's an interesting way to integrate a home movie feel into the film and it's one that is constantly reaffirmed by Becca's actions, as she makes repeated references to the way she wants things to be shot and certain lines to be said. Although there's no reason in particular why the movie wouldn't have worked better in a typical format rather than as a found footage pseudo-documentary, the way the movie was filmed didn't break my immersion.
The surprising thing about this movie is that it has a great sense of humour. The first trailer I saw for "The Visit" made me laugh, but not for the right reasons; I just thought it looked ridiculous! I was expecting some sort of bizarre supernatural story whereby two grandparents had become vessels for the devil, or perhaps Nana was trying to fatten up the children so she could eat them for supper. However, having seen the film it's very obvious that the silliness in the trailer was intentional, and whilst the movie is a bit wacky, it's meant to be that way. The film doesn't have a supernatural element as the trailer suggests, instead it has a firm grounding in mental health, ageing, and losing your connection to your family.
The first two themes listed here are obvious given the nature of Nana and Pop Pop, as both are in their later years and a little bit loco. The movie blurs the lines between the two, intertwining one with the other as Becca and Ed attempt to rationalise Nana and Pop Pop's behaviour. The latter, on the other hand, relates more to the children's loss of a father figure, and also their mother's separation from her parents. This is a clear motivation for Becca and Ed and also for their mother, as perhaps the only reason why she agrees to let them stay with Nana and Pop Pop in the first place is that she's a single parent struggling with the pressures that come along with raising teenagers, along with the fact that she feels guilty for her part in denying them an important figure in their lives. "The Visit" is about real issues that people face on a daily basis and how attempting to cope with them can lead to painful and sometimes horrific situations, which in my opinion is what sets it apart from most found footage horror films.
In addition to a strong script with a surprising amount of depth, "The Visit" is elevated by two creepy performances from Deanna Dunagan and Peter McRobbie, who are both deeply unnerving. Nana is clearly the more sinister of the grandparents, not only because her spindly frame and ghost-like complexion remind us all just how frightening little old ladies can be, but also because when she isn't acting like a woman possessed she's incredibly calm and straight faced. When she isn't running around the house or scratching at the walls she looks at the children with eyes that seem lifeless, devoid of affection and joy, meaning that no matter what she's doing she appears to be ready to attack. She's simply menacing, to a degree that a kindly old woman should never be.
Pop Pop is scary for a completely different reason. He doesn't seem quite as crazy as Nana, nor does he chase the children around under the house like a spasming spider, but it's clear that physically he is capable of doing real damage, and the fact that his mind sometimes seems to escape him makes that all the more disquieting. Pop Pop just never seems present, never quite there – there's always something clouding his mind. Deanna Dunagan and Peter McRobbie make the film what it is, because they give their characters a quirky peculiarity that's both endearing and frightening, leaving the audience wondering what on earth could be wrong with them.
Olivia DeJonge and Ed Oxenbould are also very good as Becca and Tyler, and they have a surprising on-screen chemistry. You believe that these two young actors could be brother and sister, as they squabble over the smallest of issues and throw playful jibes in one another's direction, and they really seem to get along.
"The Visit" is a stellar return to form for M. Night Shyamalan and a fantastic horror film in its own right. It's a subdued affair which burns slowly, but the performances carry it through, as Nana is a truly scary antagonist and the children are very charming. It's a smart film about ageing and the perceptions that surround it, as well as mental illness and family issues – Shyamalan at his best.
"Fear The Walking Dead" is the kind of series that I wish didn't exist, not just because it feels uninventive and cash-grabbing but because I can't help but watch it despite knowing that this is the case! "The Walking Dead" is an incredibly lucrative show for AMC so it's only natural that they would want to cash in by creating a companion series, but it feels a bit manipulative to have a show with "The Walking Dead" in the title when in actual fact it has very little to do with the flagship series. I would personally much prefer that a new show was created with gifted young writers and actors because AMC is already making its money with "The Walking Dead". Instead, we have "Fear The Walking Dead" which is basically a knock-off of "The Walking Dead" but with cheaper actors and less decayed walkers.
The reason that I'm tuning into "Fear The Walking Dead" isn't just because I watch "The Walking Dead", it's also because I want to know how the zombie apocalypse began. How did the world react to the world coming to an end when Twitter and YouTube were still prevalent? When did the dead start turning into walkers? Like when exactly – everyone is infected in "The Walking Dead" so if Nick (Frank Dillane) had died when he was hit by the car in this episode would he have turned into a walker? When did the process begin?
My interest in "Fear The Walking Dead" is clearly tied to the main show which is why I'm a bit frustrated at both AMC and myself. I don't actually like the cast and this premiere was pretty appalling, so the fact that for some reason I'm invested is incredibly annoying.
In all fairness this show has a lot going for it; it could go in a number of interesting directions because, after all, we're witnessing the start of a zombie apocalypse! There's so much going on in the city and there are so many people for the walkers to feast on, so the show could actually end up being pretty good if the writers can be bothered to try. Sadly, from what I've seen so far I have to imagine that the showrunners will take whichever road is the most travelled so that they can do as little work as possible.
This season premiere began with a typical zombie cliché, as Nick searched a creepy looking building for a girl named Gloria (Lexi Johnson), only to find that she was a walker. The sound was ominous (although clearly artificial), the lighting was dim, and shrieks of panic could occasionally be heard in the distance. What could possibly be the matter?
I was so disappointed with this opening because we've seen it before hundreds of times, and there's no surprise when a walker appears at the start of a television series about the walking dead! Why bother trying to build suspense at all? If you're going to immediately reveal your cards then there's no point in bluffing. Surely nobody was actually scared by this sequence.
I'm not a massive fan of jump scares, because most of the time they're designed to shock rather than scare which gives the name a bit of a false feel. However, in this instance I would've been quite pleased if the opening had paved the way to a comedic one, with Gloria playing a trick on Nick rather than simply being a walker. This would've established that although the show isn't going to be original, it will be fun and try to play around with genre conventions. Alas, the showrunners don't seem to have any intention of thinking outside the box, so I don't expect to see anything new or exciting.
I don't want to linger on the opening scene too much, but it really is infuriating that the showrunners couldn't have thought of a better way to introduce the story and one of the show's main characters. The showrunners could've done hundreds of different things with the setting of the church whilst still establishing that this is a show about zombies. They could've started with a drug bust, which would've been interesting because the sounds of panic could've still made the audience think that a walker was about to appear. Alternatively, they could've had a walker banging at the door trying to get in, with Nick believing that it was a dealer and thus leaving the area. He could've even seen the walker that was knocking on the door from a distance afterwards and made a joke about it looking messed up, given that from a distance it might just look like a person on a large quantity of drugs. This would've let the audience have a glimpse of a walker and also established some sort of personality within the show.
The characters, like the opening, were completely clichéd – Nick is the stereotypical screw-up junkie and as usual he's the only person in the main cast who knows the truth to begin with. But who would believe a junkie? Wow, how original. On top of that, he's part of a dysfunctional family. Madison (Kim Dickens), the mother in this family, seems pretty well put together, although her son is a junkie so we'll have to wait and see. She seems to wear the pants in the relationship with her new husband so she'll probably be a badass like Carol (Melissa McBride) is on the main show. There's also a daughter, Alicia (Alycia Debnam-Carey), who has a boyfriend, Matt (Maestro Harrell) – that's going to be her character development right there. The boyfriend dies and hey presto she becomes another lost soul hardened by the world.
Now I may be being slightly cynical and also a tad sarcastic, but come on, are the folks down at AMC joking? These characters are a disgrace! There's nothing to any of them – they're straight out of the 'Writing a Zombie Film/TV Show for Idiots' guide book.
Beyond the issues with the writing, characters, and general lack of ambition from AMC, the performances across the board were poor. I don't want to condemn any of the actors, because the fault isn't really with them, but they didn't elevate the material they were given. Frank Dillane wasn't good at all and he didn't show half as much emotion as was necessary when he was explaining what happened in the opening scene. He whispered through his lines and tried to make his eyes water, but the rest of his face didn't move and he flittered from sad to indifferent like a child in a school play.
Maybe things will get better, but right now "Fear The Walking Dead" seems like nothing more than a mediocre attempt to piggyback on the success of "The Walking Dead". Whilst the idea of gaining an insight into where the zombie apocalypse began is potentially interesting, what I saw in this premiere leads me to believe that nothing creative will be done with the premise. Overall, this premiere was incredibly dull and extremely disappointing, with very few positives to speak of.
This review contains spoilers for the third season of "Hannibal". It will mainly focus on the second half of the season.
This third season of "Hannibal" has been a tale of two halves. I thought the first half was fantastic, as we followed Hannibal's (Mads Mikkelsen) exploits in Florence and watched the supporting cast attempt to subdue him. However, the second half didn't hit the mark as far as I'm concerned, because The Red Dragon's (Richard Armitage) storyline was streamlined so that the show could focus more on Will (Hugh Dancy) and the way that Hannibal's influence was impacting his personality. Nevertheless, the finale was satisfying and I believe that it was a beautifully brutal way to end the series.
I've heard the word 'focused' thrown around regarding the second half of season three, but I think that evaluation is misguided. In my opinion there was actually a complete lack of focus, because while Francis Dolarhyde (The Red Dragon) was introduced and frequently visited, his story was bare and without context – I never felt as though the story was centred around him. Dolarhyde wasn't developed at all, so although the narrative was clearer when he was involved, his involvement felt like a distraction.
Dolarhyde is supposed to be a man damaged by the world, treated like an outcast by everyone other than his abusive grandmother, due to his speech impediment and physical appearance. This leads to psychological damage, which in turn leads to delusion and psychosis. None of this is clear in this adaptation because we just don't know anything about Dolarhyde – he's nothing more than a villain for Will to chase; a reason for him to be reunited with Hannibal.
This not only took away from what I thought was a decent performance from Richard Armitage, but also ruined the character of Reba (Rutina Wesley), because we didn't see what Dolarhyde as a man was really about. Yes, he's a horrible killer, but he's also lonely and has never felt real love. Reba shows him affection, and he can shed the shackles of the dragon because she can't see him – his disability is masked by her's, which has a certain beauty in the novel which is lost here. I feel that this is truly a shame, because if any show could've done The Red Dragon's story justice it would be this one, given the show's focus on psychology and the general intelligence which has been displayed since the start of season one.
I was really looking forward to seeing The Red Dragon on "Hannibal", because in Thomas Harris' novel the origin of his madness is compelling, and I thought that the television show would thrive in exploring this, due to the nature of the show and also because of the amount of time available to tell the story. Sadly, we weren't afforded any proper insight into Francis Dolarhyde's past, so he didn't feel like a fully-formed character. This was incredibly apparent because everyone else on the show has had three seasons to establish themselves. We should've felt sorry for Dolarhyde because of all he had been through, but instead he came across as a monster, and ultimately he felt like a spare part in his own story.
Having said all that, I should note that I didn't hate the entirety of the second half of season three; it's just that my expectations were extremely high given what had come before. There were many memorable moments to take from the last half of this season, particularly Doctor Chilton's (Raúl Esparza) gruesome treatment at the hands of the Dragon, which was harrowing even on a show about a psychologically deranged cannibal. I was pleased that the show didn't use Freddie Lounds (Lara Jean Chorostecki) for that moment like the book did, because on the show she isn't nearly as interesting a character as Chilton is, as she hasn't had as much time on screen over the course of the series. I felt a great deal of sympathy for Chilton as he faced the Dragon, because although he can be despicable I don't think he's that bad on a show filled with morally grey individuals, he just wanted to be exceptional and never really was.
The performances throughout the season have been superb, especially those of Mads Mikkelsen and Hugh Dancy, who have developed a real on screen chemistry. Their relationship blossomed into something of a love story at the end of season two, and that continued in season three. Their affection for each other was amazingly portrayed over the course of the season, especially because it was mixed with anguish due to the pain that Hannibal had inflicted on Will since episode one.
Mikkelsen has a disturbing presence, controlling the screen whenever he's around, which is even more evident when he's appearing in scenes with Dancy, due to Will's attraction towards him. Dancy plays Graham as though he is a super-intelligent alien visiting our world, understanding everything that's going on around him whilst simultaneously feeling confused by it. He never seems settled or satisfied, which is perhaps accentuated by the psychological torture that he endures whenever he is around Hannibal.
As the show has progressed Will has altered drastically, as Hannibal has sunk his teeth in and shown him how good it can feel to take control. To me this evolution is the essence of the show, so it was incredibly satisfying to see Will give in to Hannibal right before the end credits rolled, orchestrating his escape and also a final showdown with the Dragon. Their cooperation in taking down Dolarhyde was an ingenious way for the season to close, because it gave both characters what they wanted whilst preserving their personalities. Hannibal had shown Will what he was missing and Will had liked it, but Will also knew that if he let Hannibal escape they would both kill again. Jumping off that cliff finished the whole sordid saga, because it was the only way to be sure that Hannibal wouldn't kill Alana (Caroline Dhavernas), Jack (Laurence Fishburne), and many more. It was an almost Shakespearean finale, ending "Hannibal" in the poetic way that it deserved.
All in all, "Hannibal" season three made for great entertainment, even if it was a bit disappointing at certain junctures. I loved the first half of the season, and although I felt that The Red Dragon's story was wasted I still thought his role in the final sequence was fantastic and meant that his character felt necessary. The series petered out towards the end, so perhaps it is a good thing that NBC aren't going to renew it for a fourth season, but it still gave us one last brilliant episode. It wasn't perfect, it lost a lot of steam, but "Hannibal" season three was solid and the series as a whole has been truly great.


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Google Breaks Promise from 2005 to Never Ever Show Banner Ads in Search Results
Promises are made to be broken but in the open, high profile world of corporate promises, you'd at least think one of the biggest, Google, would keep its promises.
First seen reported on the guardian.com, Google searches for "southwest airlines" are returning searches with big, Southwest themed large banners at the very top of the SERP.
Google has secretly recently started testing showing banner ads above organic and paid search results, allegedly breaking its 2005 promise to "never show banner ads in search results". First reports of these Google banner ads started trickling in on the 24th and the ads reportedly take up the entire width of the browser screen. I tried repeatedly to find the banner ads myself, but to no avail.
Marissa Mayer, VP of Search Products at Google in then, 2005 made an announcement on the Google's corporate blog that banner ads will never appear in search. "There will be no banner ads on the Google homepage or web search results pages.", she wrote. Looks like that promise is in the testing phases of being broken.
My contact at Google said the testing is isolated and appears to have been temporarily taken offline, meaning its doubtful that right now anyone is seeing these banner ads in search results. However, I highly doubt this new "feature" of Google search will be thrown out. Most likely, it's just being tweaked and we will soon see banner ads like the one from a recent Southwest Airlines search performed below.
Here's the deal with these banner ads. It appears they will likely only show for branded search results. Seeing a Southwest themed banner ad like the one above on random and generic search queries like "cheap airfare" would be a huge issue for both airline companies and consumers alike. In other words, it is highly doubtful banner ads will ever appear for anything other than branded searches.
Google is constantly turning into a big one page advertisement for branded search results. Want to search for Delta flights? Soon you'll likely see a search results page with Wiki-esque info on the right, Delta's banner ad at the top, recent news, images, social activity, etc. Most likely future searches will return only a single URL above the fold…if not just the single URL on the first page results at all.
In reality, 2005 was a long time ago and Marissa Mayer likely took her promises to Yahoo with her when she left Google. Google's job is to increase its profits and since search result ads make up more than 95% of it's revenue, it's likely you'll continue to see changes and optimizations from Google that are designed to increase revenue from ads and protect big brands.
Written by steffan on October 27, 2013 — Leave a Comment
Tags google, seo
« New Google Penguin 2.1 Update Throws SEOs Into a Tizzy
SEO Articles, Updated for 2019 »


text:
Q: Update numeric and float fields in elasticsearch client I am bit new to elasticsearch client.
I have not done any type of predefined mapping to any field, because I might add some new field to the documents in future.
My data looks like this:-
{
    "segmentId": "4700-b70e-881",
    "segmentName": "test",
    "data": "This is a test data",
    "dataId": "70897e86-9d69-4700-b70e-881a7f74e9f9",
    "augmented": false,
    "createdBy": {
        "email": "2010abinas@gmail.com",
        "primaryKey": "902d2b57-54e6",
        "secondaryKey": "adcc-f20423822c93"
    },
    "status": "active",
    "createdAt": 1617422043554,
    "updatedAt": 1617422043554
}

I wanted to update 3 fields by using updateByQuery.
I was trying below approach.
await esClient.updateByQuery({
    index: "data",
    type: "doc",
    refresh: true,
    body:{
        query:{
            match: {
                dataId: "70897e86-9d69-4700-b70e-881a7f74e9f9"
            }
        },
        script:{
            lang:"painless",
            source:`ctx._source.data='This is updated test data';ctx._source.updatedAt=${Date.now()};ctx._source.segmentId=null`
        }
    }
})

I am getting compilation error because of updatedAt and segmentId, When I pass as string it works, like:-
source:`ctx._source.data='This is updated test data';ctx._source.updatedAt='${Date.now()}';ctx._source.segmentId='null'`

A: I found a way to solve the above issue,
await esClient.updateByQuery({
    index: "data",
    type: "doc",
    refresh: true,
    body:{
        query:{
            match: {
                dataId: "70897e86-9d69-4700-b70e-881a7f74e9f9"
            }
        },
        script:{
            lang:"painless",
            source:`ctx._source.data='This is updated test data';ctx._source.updatedAt=params.date;ctx._source.segmentId=params.segmentId`,
            params:{
                date: Date.now(),
                segmentId: null
            }
        }
    }
});

redpajama_set_name: RedPajamaStackExchange


The first Sustainable Hackney Films for Action screening of the year will be The Chocolate Case, in partnership with Hackney Fairtrade to coincide with Fairtrade fortnight (25th Feb - 10th March). Discover the other exciting Fairtrade events happening that week here.
Cllr Carole Williams: Cabinet Member for Employment, Skills and Human Resources with a responsibility for equalities.
Join us on Friday, 1st March at St Paul's Church Hall.
Chocolate is something you must have. But if you knew that every time you buy a chocolate bar you help finance child slavery in Africa, the sweet taste would soon turn bitter. And this is precisely what the three Dutch journalists and old friends Maurice, Teun and Roland find out as they dig deeper and deeper into the covert farmlands of the cocoa industry. A revealing and dramatic detective story with three idealistic – and cheerful – gentlemen in the lead role. And a story that takes a new twist when the three friends, after many shocking discoveries and disappointments, decide to take matters into their own hands and quite simply start their own chocolate company! Tony's Chocolony is 100% slavery-free and is now one of Holland's leading chocolate brands. 'The Chocolate Case' is just as rich in surprises as a Kinder egg, but will make even the most committed chocolate enthusiast think twice each time a craving for chocolate arises.


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text:
Artists / Bands
Selten gehörte Musik
In the Exhibition
»Selten gehörte Musik« (Rarely Heard Music) is a group project by artists from the Wiener Gruppe (Vienna Group), the Vienna Actionists, and their artist friends who gathered together in Berlin in the 1970s after leaving Vienna more or less voluntarily—in part, because of scandals incited by their art.
Gerhard Rühm had already turned his back on the narrow-minded conservative (»stuffy«) Vienna in 1964 and moved to Berlin. Günter Brus fled there in 1969 to avoid the police measures awaiting him through his sentencing in the aftermath of the action Kunst und Revolution (Art and Revolution, 1968). H. C. Artmann and Oswald Wiener had also relocated to Berlin, and Dieter Roth was a frequent guest.
This circle of friends carried out many joint artistic activities. In 1969, for example, Brus founded the magazine Die Schastrommel (The Old Gossip Monger), ironically titled the »organ of the Austrian exile government,« which offered him and his artist colleagues a publication forum that, among other things, documented their activities in the 1960s.
They also met for joint literary work (Berliner Dichterworkshops [Berlin Poets' Workshops]). This was the framework in which they put music—which also included voice articulations such as singing, laughing, whistling, and other such sounds—in the foreground for the first time on July 12–13, 1973. This led to the »Selten gehörte Musik« project as a spontaneous form of musical interaction that intentionally did not follow any style. Initially, it was just recorded on audiotape but then, in 1974, they decided to make public appearances.
The first concert was at the Lenbachhaus in Munich in May 1974 (with Brus, Nitsch, Roth, Rühm, and Wiener), which was followed by another at the Kirche zum Heiligen Kreuz in Berlin-Kreuzberg in September of the same year, in which Christian Ludwig Attersee, Dominik Steiger, and Arnulf Rainer participated. Rainer's contribution consisted of physical poses which he improvised to the music by his friends. Two days later, they appeared as part of an Attersee exhibition at the Kunstverein (arts association) of Kassel with Ingrid Schuppan participating in place of Wiener who was ill at the time.
»Selten gehörte Musik« can be viewed as an early example of the free and in part intentionally dilettantish interplay of visual artists which then became a program for many artists in the 1980s. In the case of »Selten gehörte Musik,« the musical conditions of the protagonists were very different: Rühm was a trained concert pianist who had also studied composition; Wiener was a jazz trumpeter; Attersee had originally wanted to become an opera singer and had been musically active for a long time. In Nitsch's work, music had always played an important role. Only Brus and Roth as performers were musical amateurs, even if they did have a lot of knowledge.
Concert at Lenbachhaus, Munich, May 1974, 1:57:28 h., with Günter Brus, Hermann Nitsch, Dieter Roth, Gerhard Rühm, Oswald Wiener
Ominous accordion and tuba sounds, along with a violin that is mistreated rather than being played correctly, and finally pizzicati set pointedly into the rugged listening landscape. That is how the »Selten gehörte Musik« concert at Lenbachhaus in Munich began in 1974. The five-person group continued for two hours with a spontaneous and free-spirited flow of communicating and responding, going off alone at some point only to then rejoin the common, heterogeneous group of sounds. Ever new beginnings, with new instruments joining in (flute, organ, saxophone and even a megaphone), the entrances of which repeatedly created laughter among the audience—the five proto-dilettantes thus created an arch of suspense collectively creating a dynamic multi-construct. There was even time for embedded noise bursts that tended to be violently atonal in a fluctuating way before the stream of improvisation glided back to more sustained, harmonious waters. Insistent chiming sounds broke the flow, while even more persistent strikes of a cymbal pushed it back together. And thus it ebbed and flowed on this exuberant evening in the high-principled, White Cube ambience that was captured by photographer Karin Mack in contrasting black-and-white images. At the end, an abrupt, humorous »conference« is held with an agitated audience that thankfully accepts its role in this para-musical action theater.
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Poster, Selten gehörte Musik, for the concert at Lenbachhaus, München, May 1974 ...more
Advertising Poster, 35.04 x 19.69 inches. Image via fondazionebonotto.org
Christian Höller


I will be teaching sensory-somatic theater, Luciani's Absolute Theater's Technique this fall in San Francisco. The training will take place at SAFEhouse Arts as part of their RAW (Resident Artists Workshops) program. More information to follow. Please contact me if interested in participating or finding out more.
Originally from Caracas, Venezuela, Guido Luciani recently relocated back to Los Angeles. The artist's experience spans many years, several countries and many artistic forms of expression including, but not limited to: fine and performing arts photography, theater and film directing, editing and writing and; performing arts training. Guido is also the creator of the "Resonance Technique" for performers and the "Absolute Theater".


We're Told That:Egyptian Beliefs = Mythology.Roman Beliefs = Mythology.Greek Beliefs = Mythology.Yoruba Beliefs = Mythology.
Arabian Beliefs = Truth.Jewish Beliefs = Truth.
If We Ignored The Fact That These "Truths" Were Used As A Tool To Invade Our Lands & To Enslave Us, Then May I Ask WHO Certified Them As "Truths" … ?!. WHY Are These "Truths" Convenient Only To The Invaders??!!. And, After The End Of Slavery, Why Are These "Truths" Not Uniting Us, Bringing Economic Development To Our Lands, & Increasing Our Standard Of Living???!!!
I Know That I May Not Get Any Valid Response To This Post, If At all. That Is Quite Understandable. But What I Refuse To Understand Is WHY Is The FEAR Planted In Our Ancestors Allowed To Grow Into An All-encompassing Monster In Us?. The Answer To This Is Simple: Slavery Has Evolved… From Physical To Mental, & By Extension, Spiritual. Oh Yes, There Is Also Spiritual Slavery!
Borrowing from Late Bob Marley's lexicon, we need to emancipate our minds from mental-spiritual-slavery so as to free our souls.


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HLA (2016) 88:334-41
Human Immunology (2016) 77:1329-34
International Journal of Immunogenetics (2016) 43:426-33
The following sequences have been submitted to the Nomenclature Committee since the August 2016 nomenclature update and, following agreed policy, have been assigned official allele designations. Full details of all sequences will be published in a forthcoming report.
Below are listed the newly assigned sequences (Table 1) and confirmations of previously reported sequences (Table 2). The accession number of each sequence is given and these can be used to retrieve the sequence files from the EMBL, GenBank or DDBJ data libraries. Although accession numbers have been assigned by the data-libraries and most sequences are already available, there is still the possibility that an author may not yet have allowed the sequence to be released; in such a case you will have to contact the submitting author directly. Additional information pertaining to new sequences is often included in the publications describing these alleles; a listing of recent publications that describe new HLA sequences is given in Table 3. The sequence of A*30:02:12 has been shown to be identical to A*30:100 and therefore A*30:02:12 has been abandoned.
A*01:01:01:04 RDP-CH2-65 KX707637, Carolyn K Hurley, Washington DC, USA
A*01:01:76 10588 LT616958, Maria Loginova, Kirov, Russia
A*01:214 DKMS-LSL-A-740 LN994641, DKMS Life Sciences Lab, Dresden, Germany
A*01:217 23285 LT616959, Maria Loginova, Kirov, Russia
A*02:01:01:10 BY01308 KX707632, Carolyn K Hurley, Washington DC, USA
A*02:01:123 DKMS-LSL-A-723 LN994624, DKMS Life Sciences Lab, Dresden, Germany
A*02:01:124 DKMS-LSL-A-720 LN994622,LN994621, DKMS Life Sciences Lab, Dresden, Germany
A*02:93:02 DKMS-LSL-A-810 LN994711, DKMS Life Sciences Lab, Dresden, Germany
A*02:197:02 HG00012237 KX545277, Histogenetics, Ossining, USA
A*02:610:02 DKMS-LSL-A-754 LN994655, DKMS Life Sciences Lab, Dresden, Germany
A*02:644 HG00011823 KX060756, Histogenetics, Ossining, USA
A*03:262N DKMS-LSL-A-806 LN994707, DKMS Life Sciences Lab, Dresden, Germany
A*11:251N AMC160621_50662775 KX842484, Oh-Joong Kwon, Seoul, South Korea
A*23:76 DKMS-LSL-A-495 LN994609, DKMS Life Sciences Lab, Dresden, Germany
A*24:356 DKMS-LSL-A-743,DKMS-LSL-A-738 LN994644,LN994639, DKMS Life Sciences Lab, Dresden, Germany
A*26:01:41 DKMS-LSL-A-765,DKMS-LSL-A-762 LN994666,LN994663, DKMS Life Sciences Lab, Dresden, Germany
A*26:132 C16-1545 KX545368, Eun-Jeong Choi, Seoul, Korea
A*31:01:25 JRC-D79-094 LC185088, Masahiro Satake, Tokyo, Japan
A*32:01:24 DKMS-LSL-A-739,DKMS-LSL-A-913,DKMS-LSL-A-831 LN994640,LN999601,LN994732, DKMS Life Sciences Lab, Dresden, Germany
A*32:92N DKMS-LSL-A-760,DKMS-LSL-A-897 LN994661,LN999585, DKMS Life Sciences Lab, Dresden, Germany
A*33:120 JRC-D36-055 LC186054, Masahiro Satake, Tokyo, Japan
A*68:157 HG00012268,HG00012269 KX711907,KX711908, Histogenetics, Ossining, USA
B*08:01:01:03 RDP-CH6-85 KX707641, Carolyn K Hurley, Washington DC, USA
B*08:166 HG00012283 KX646302, Histogenetics, Ossining, USA
B*15:405 JRC-D08-071 LC183866, Masahiro Satake, Tokyo, Japan
B*38:65 HG00012300 KX765870, Histogenetics, Ossining, USA
B*44:53:02 HG00012285 KX646311, Histogenetics, Ossining, USA
B*46:70 JRC-D01-358 LC183865, Masahiro Satake, Tokyo, Japan
B*51:01:54 167469KJA KX506776, Maria Elisa Moraes, Rio de Janeiro, Brazil
B*52:62 HG00012286,HG00012287 KX711916,KX711917, Histogenetics, Ossining, USA
B*53:44 JF10243,257719 KX611136, Raquel Fabreti, Belo Horizonte, Brazil
B*55:80 5791500612 KX827289, Faming Zhu, Hangzhou, China
C*01:02:41 DKMS-LSL-C-1303 LT599373, DKMS Life Sciences Lab, Dresden, Germany
C*01:128 DKMS-LSL-C-1259 LT599316, DKMS Life Sciences Lab, Dresden, Germany
C*02:02:02:04 RDP-CH3-24 KX711699, Carolyn K Hurley, Washington DC, USA
C*02:02:02:05 DKMS-LSL-C-1280 LT599338, DKMS Life Sciences Lab, Dresden, Germany
C*02:02:31 DKMS-LSL-C-960 LN999648, DKMS Life Sciences Lab, Dresden, Germany
C*02:122 DKMS-LSL-C-938 LN999626, DKMS Life Sciences Lab, Dresden, Germany
C*02:125 HG00012315 KX711936, Histogenetics, Ossining, USA
C*03:35:02 DKMS-LSL-C-1313,DKMS-LSL-C-1339 LT599382,LT599405, DKMS Life Sciences Lab, Dresden, Germany
C*03:119:02 DKMS-LSL-C-1280 LT599337, DKMS Life Sciences Lab, Dresden, Germany
C*03:341 RDP-CH5-43 KX686519, Carolyn K Hurley, Washington DC, USA
C*05:78:02 HG00012324 KX765873, Histogenetics, Ossining, USA
C*06:102:02 DKMS-LSL-C-946 LN999634, DKMS Life Sciences Lab, Dresden, Germany
C*07:314:03 DKMS-LSL-C-1277,DKMS-LSL-C-1285 LT599334,LT599355, DKMS Life Sciences Lab, Dresden, Germany
C*07:551N DKMS-LSL-C-1255 LT599312, DKMS Life Sciences Lab, Dresden, Germany
C*08:141Q DKMS-LSL-C-1351 LT599415, DKMS Life Sciences Lab, Dresden, Germany
C*14:75 DKMS-LSL-C-944 LN999632, DKMS Life Sciences Lab, Dresden, Germany
C*14:76 DKMS-LSL-C-1336 LT599343, DKMS Life Sciences Lab, Dresden, Germany
C*14:79 HG00012321 KX711927, Histogenetics, Ossining, USA
C*15:132 DKMS-LSL-C-956,DKMS-LSL-C-1274,DKMS-LSL-C-1312 LN999644,LT599331,LT599381, DKMS Life Sciences Lab, Dresden, Germany
DPB1*602:01 HG00012347 KX711958, Histogenetics, Ossining, USA
DPB1*611:01 HLA-160912 LC180164, Yuto Horie, Kyoto, Japan
DPB1*612:01 SZ-168 KX833250, Hong-Yan Zou, Shenzhen, China
DQB1*02:76 HG00012330 KX646337, Histogenetics, Ossining, USA
DQB1*03:01:34 SZ-167 KX833252, Hong-Yan Zou, Shenzhen, China
DQB1*05:131 HG00012174 KX425993, Histogenetics, Ossining, USA
DRB1*01:78 HG00012345 KX711950, Histogenetics, Ossining, USA
DRB1*11:206 HG00012343 KX711944, Histogenetics, Ossining, USA
DRB1*15:02:18 HG00012337 KX711943, Histogenetics, Ossining, USA
DRB3*01:41 HG00011710 KU992579, Histogenetics, Ossining, USA
A*01:23 AN00189, LT596639, Steven GE Marsh, London, United Kingdom
A*02:08 209-15, KX830962, Reem Ameen, Jabriya, Kuwait
A*02:17:02 AN00199, LT596649, Steven GE Marsh, London, United Kingdom
A*02:131 AN00185, LT596634, Steven GE Marsh, London, United Kingdom
A*02:189 SZGSQ-28, KX787493, Su-Qing Gao, Shenzhen, China
A*03:01:39 DKMS-LSL-A-711, LN994612, DKMS Life Sciences Lab, Dresden, Germany
A*03:157:02 DKMS-LSL-A-748, LN994649, DKMS Life Sciences Lab, Dresden, Germany
A*03:195 DKMS-LSL-A-716, LN994617, DKMS Life Sciences Lab, Dresden, Germany
A*30:100 HG00005755, KC503857, Histogenetics, Ossining, USA
A*32:62 DKMS-LSL-A-713, LN994614, DKMS Life Sciences Lab, Dresden, Germany
A*68:18N DKMS-LSL-A-744,DKMS-LSL-A-784, LN994645,LN994685, DKMS Life Sciences Lab, Dresden, Germany
A*68:38 JRC-D44-084, LC185087, Masahiro Satake, Tokyo, Japan
B*07:48 SZGSQ 31, KX827240, Su-Qing Gao, Shenzhen, China
B*15:01:01:05 RDP-CH4-79, KX707644, Carolyn K Hurley, Washington DC, USA
B*15:34 AN00196, LT596646, Steven GE Marsh, London, United Kingdom
B*15:37 Ho-B1537, KX5555571, Chak-Sum Ho, Ann Arbor, USA
B*15:152 JRC-D31-035, LC177793, Masahiro Satake, Tokyo, Japan
B*18:72:02 HG00012282, KX711912, Histogenetics, Ossining, USA
B*35:02:01 121-14, KX815339, Reem Ameen, Jabriya, Kuwait
B*35:17:01 LC167, KX825916, Konstantinos Barsakis, Palo Alto, USA
B*40:04 EC, LT596650, Steven GE Marsh, London, United Kingdom
B*55:72 HG00012291, KX711914, Histogenetics, Ossining, USA
B*57:04:01 AN00193, LT596643, Steven GE Marsh, London, United Kingdom
C*01:07:02 DKMS-LSL-C-1283, LT599353, DKMS Life Sciences Lab, Dresden, Germany
C*02:25Q DKMS-LSL-C-1246, LT599303, DKMS Life Sciences Lab, Dresden, Germany
C*02:80 DKMS-LSL-C-1293, LT599363, DKMS Life Sciences Lab, Dresden, Germany
C*03:04:12 JRC-D79-089, LC185345, Masahiro Satake, Tokyo, Japan
C*03:309 DKMS-LSL-C-1340, LT599347, DKMS Life Sciences Lab, Dresden, Germany
C*04:01:01:05 DKMS-LSL-C-1354, LT599350, DKMS Life Sciences Lab, Dresden, Germany
C*04:01:01:05 RDP-CH5-37, KX711700, Carolyn K Hurley, Washington DC, USA
C*04:06 HG00012133, KU360755, Histogenetics, Ossining, USA
C*04:07 AN00188, LT596638, Steven GE Marsh, London, United Kingdom
C*05:51Q DKMS-LSL-C-969, LN999657, DKMS Life Sciences Lab, Dresden, Germany
C*06:16N DKMS-LSL-C-964, LN999652, DKMS Life Sciences Lab, Dresden, Germany
C*06:171N DKMS-LSL-C-1296, LT599366, DKMS Life Sciences Lab, Dresden, Germany
C*07:462 DKMS-LSL-C-1270,DKMS-LSL-C-1355, LT599327,LT599418, DKMS Life Sciences Lab, Dresden, Germany
C*07:512 HG00012307, KX646327, Histogenetics, Ossining, USA
C*12:03:01:04 DKMS-LSL-C-1268,DKMS-LSL-C-1267,DKMS-LSL-C-1338_C*12new,DKMS-LSL-C-1294, LT599325,LT599324,LT599345,LT599364, DKMS Life Sciences Lab, Dresden, Germany
C*15:09 LC21, KX825915, Konstantinos Barsakis, Palo Alto, USA
C*18:01 113-14, KX756584, Reem Ameen, Jabriya, Kuwait
DPB1*45:01 DKMS-LSL-DPB1-1384,DKMS-LSL-DPB1-1385, LT599447,LT599448, DKMS Life Sciences Lab, Dresden, Germany
DPB1*46:01:01 DKMS-LSL-DPB1-1386,DKMS-LSL-DPB1-1387, LT599449,LT599450, DKMS Life Sciences Lab, Dresden, Germany
B*46:01:22 (12)
DRB1*14:127:01 (14)
DRB1*15:112 (15)
Yang KL, Chen SP, Lin PY.Identification of a novel HLA-A*02 variant, HLA-A*02:621, in a Taiwanese bone marrow donor. HLA 2016 88: 194-195.
Lin CY, Chang CL.HLA-A*11:134, a novel HLA-A*11 variant, identified by sequence-based typing in a Taiwanese individual. HLA 2016 88: 195-196.
Street J, Davies E, Harvey C, et al.Two new HLA class I alleles - A*11:241 and C*08:132. HLA 2016 88: 196-197.
Ulrich S, Posch U, Helmberg W, et al.HLA-A*68:02:11, a new HLA-A*68 allele identified during family typing. HLA 2016 88: 197-198.
Yang KL, Lin PY.Identification of a novel HLA-B*07 variant, B*07:269, by sequence-based typing in a Taiwanese bone marrow stem cell donor. HLA 2016 88: 198-199.
Rampim GF, Araujo AS, Mourao TB, et al.HLA-B*15:04:04, a novel HLA allele identified during proficiency testing in Brazil HLA 2016 88: 200-201.
Li JP, Li XF, Zhang X, et al.The novel HLA-B allele, HLA-B*15:226N, was identified by sequencing genomic DNA in a platelet donor. HLA 2016 88: 201-203.
Thomsen D, Christiansen M, Medina C, et al.Discovery of a novel HLA-B*15 allele, B*15:379, in a patient from Guinea-Bissau HLA 2016 88: 203-204.
Yang KL, Lin PY.HLA-B*15:388, a novel variant of HLA-B*15, discovered in a Taiwanese individual. HLA 2016 88: 204-205.
Yang KL, Chen SP, Lin PY.Detection of a novel HLA-B*46:01 variant, HLA-B*46:01:22, in a Taiwanese individual. HLA 2016 88: 205-206.
Li XF, Zhang X, Lin FQ, et al.Identification of a novel HLA-B*46 allele, HLA-B*46:28. HLA 2016 88: 206-208.
Yang JH, Jiang YQ, Sun Y, et al.Identification of a novel HLA-DRB1*14 allele, HLA-DRB1*14:127:01, in a Chinese individual. HLA 2016 88: 208-209.
Street J, Harvey C, Johnson J, et al.A further HLA-DRB1*15 family allele - DRB1*15:112. HLA 2016 88: 209-210.


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Hang fork group: this " lithium" is unusual
Exhibitors Interview of Asia Logistics Exhibition
As one of China's largest professional forklift R & D and manufacturing groups, Hangfork Group Co., Ltd. presented its ten new products at this Cemet exhibition. Under the trend that green, environmental protection and intelligence have become the development theme of the times, the X - C series new energy forklifts and Hang - C series lithium batteries released by Hang - fork Group at the exhibition site will have a significant impact on the industry.
Mr. Xu Xiang, director of the Hangfork Electric Forklift Research Institute, said: " XC series of new energy forklifts adopt a new cross-border shape and are designed to replace internal combustion forklifts. The car adopts a special structure, breaks through the traditional design method of electric forklift truck, integrates the advantages of internal combustion forklift truck and electric forklift truck, and is far superior to the traditional lithium battery model modified by lead-acid battery in performance, waterproof grade, vision, ergonomics and other aspects. "
The Hangfork - C series lithium battery configured by X - C series new energy forklift is a special lithium battery developed jointly by Hangfork Group and Ningde Times. Hangfork - C series lithium batteries have the characteristics of strong environmental adaptability, long cycle life, maintenance-free and high reliability, which provide a lasting and strong power for XC series new energy forklift trucks and guarantee for replacing internal combustion forklift trucks.
Mr Chen saimin, assistant general manager / secretary of the board of directors of Hangzhou fork group, said: " under the impetus of new energy and environmental protection, electric forklifts have become a development trend in the industry. In the international market, electric forklifts have already occupied 60 % of the market share of motor industrial vehicles, while China currently accounts for only about 25 % - 30 %, so it still has great market potential. Driven by the national environmental protection policy, the traditional forklift powered by internal combustion engine is being phased out. "
Hangzhou fork group is one of the earliest manufacturers involved in intelligent industrial vehicles in China. under the environment of industry 4.0 and clean production, the labor cost is gradually rising, and the demand for AGV products is increasing year by year. Hangzhou fork group foresees this situation, so it has carried out research and development in the field of forklift intelligence since 2012 and set up an intelligent technology company affiliated to Hangzhou fork group, which has in-depth and extensive cooperation with professional teams including Harbin institute of technology and Sweden NDC company. the product project has been successfully applied to well-known enterprises in the fields of automobiles, rubber, medicine, photovoltaic and so on. Mr Chen saimin revealed: " under the background of clean and intelligent development, Hangzhou fork group has maintained a steady and upward growth in recent years, especially in 2018, with sales of 100,000 units by the third quarter. We have strong confidence in the future market prospect and expect to maintain a business growth level of more than 10 % in 2019. "
Hangzhou fork group has been participating in CeMAT exhibition for three consecutive years. Mr Chen saimin said that intelligent and new energy products are increasingly appearing at the exhibition and have become a topic of common concern to the audience and exhibitors.


Sponsoring my child, Peace, at Hands of Love is one of the most important things I have ever done. Like most of the children there, she came in off the streets, hungry, scared, lonely, and without a family to care for her. Through my annual mission trips, I have seen her blossom from a frightened, undernourished child, to a spunky, energetic little girl. This precious child, who is completely dependent upon my sponsorship for her most basic needs, has come to think of me as her "Mum". As her Mum, I have been blessed beyond measure to be able to make a tangible and lasting difference in her life.
Break the cycle of hopelessness by helping a child realize his or her full potential. Child sponsorship starts at $45 per month.
We rescue abandoned babies and children left to fend for themselves in the streets and bush of Uganda. Through our child sponsorship program, we meet basic needs, educate through graduation, and share the love of God. Within our two orphanages, nearly 2,000 children are being nurtured and encouraged in a safe environment. These children are the hope of the future as they grow into the men and women God created them to be, with the potential to effect real change in their families, businesses, communities, and nation.
We also support a team of partners that equips Ugandan individuals through a variety of programs, enabling them to advance Christ's kingdom. We join our partners by extending their reach with shared visions of providing relief, hope, and a future for some of the most vulnerable children on earth as well as educating and empowering Ugandans to cause transformation.
Hands of Love School Produces Top 2 Math Students in Uganda!
Hands of Love's First Graduating Class!


This is a best-seller and likely because it is really easy to know just what amount of food you have and for how long. For instance; if you want food for a family of 4 for one month then purchase 8 of these buckets and you have breakfast, lunch, and dinner for a family of 4 for one month.
Stocking up on food for long-term storage has never been easier thanks to our survival and emergency food kits and buckets. These emergency food buckets ration the perfect amount of food to power you through any situation. Backed by the longest shelf life in the industry, each freeze dried meal is rich in flavor and nutrition, offering that home cooked taste without all the time-consuming preparation. Simply add hot water and you'll be able to enjoy delicious favorites like macaroni and cheese, lasagna, and scrambled eggs anywhere, anytime. And with a 30 Year Taste Guarantee, you can rest assured that these emergency food kits will stay delicious in the long run. Mountain House has been the top brand of freeze dried food for over 50 years!
This stackable 14-day boxed kit contains a variety of popular breakfast, lunch and dinner entrees for one person. Made to be compact and easy to store, this kit measures less than 19" x 12" x 16".
Biscuits & Gravy 3x — Hot fluffy buttermilk biscuits with creamy pork sausage gravy make for a hearty, family-favorite. Each pouch makes 2 1-cup servings.
Eggs & Bacon 2x — The comforting taste and smell of crispy, crumbly bacon combined with scrambled eggs. Each pouch makes 1.5 1-cup servings.
Granola with Milk & Blueberries 2x — Perfect with hot or cold water, our Granola and Blueberries has fueled everyone from United States Special Forces to explorers on Antarctic expeditions, and everywhere in between. Made with crunchy sweet granola with real blueberries and milk. Prepared hot or cold, it is a great way to start any day. Each pouch contains 2 ½-cup servings.
Rice & Chicken 3x — Rice and chicken in a savory sauce accented with pimentos makes for a delicious meal anytime, anywhere. Each pouch makes 3 1-cup servings.
Beef Stew 2x — Made with tender dices of all natural beef, potatoes, peas, and carrots. A long-time Mountain House classic. Each pouch makes 2.5 1-cup servings.
Beef Stroganoff 2x — Tender beef, noodles, and mushrooms smothered in a rich sour cream sauce. One of our most popular meals! Each pouch makes 2.5 1-cup servings.
Lasagna with Meat Sauce 2x —Pasta with chees in a rich tomato meat sauce. A favorite Italian style entrée. Each pouch makes 2.5 1 ¼-cup servings.
Macaroni & Cheese 2x — Classic comfort food. Macaroni noodles in a smooth, creamy, and very cheesy sauce. Each pouch makes 3 1 ¼-cup servings.
Mexican Rice & Chicken 2x — Spicy rice, beans, and chicken seasoned with tomato, peppers and olives. A quick and easy dinner with a kick. Each pouch contains 3 1-cup servings.
The Mountain House 50-year legacy of providing the best freeze dried and emergency food available means you can trust their meals to be dependable and delicious no matter what. Mountain House is the only emergency food brand with a Taste Guarantee. Purchase with the promise that their meals will still taste good 30 years after they were made. This is the longest proven shelf life in the industry. Period. This makes it easy to see why Mountain House is the wise food storage choice.


Annabel Scholey in the SS18 Tropic Kaftan for Fabric Magazine. The British actress was interviewed, for the April issue of the magazine, about her latest project - BBC Drama, The Split. Annabel has also starred in well-known series such as 'Britannia' and Netflix's 'Medici: Masters of Florence'.
Shop the Tropic Kaftan here.


PELLSTON -- Camp Cool returns to Pellston this summer, under the direction of Emily Matelski.
Camp Cool takes place inside Pellston Elementary School and is a enrichment program for kindergarten through fifth-grade children. Camp runs 7:30 a.m.-6 p.m. May 29-Aug. 24. Cost for the camp is $18 per full day and $14 for a half day.
Camp Cool activities include games, crafts, activities, field trips and a snack each day. Free breakfast and lunch is included. Each week will feature daily themes and there are several field trips planned throughout the summer. Cost for the field trips is included in the $10 registration fee. Themes include Kids in the Kitchen, Wonderfully Wacky Wednesday and Wet & Wild Friday.
Attendance options are daily or weekly. Payment, including registration fee, is expected prior to the camper beginning a session.
Camp Cool is operated by elementary school teacher Emily Matelski with the assistance of several Pellston Public School paraprofessionals. Each employee has taken part in the state licensing process and completed infant/child first aid and CPR certification.
For more information or to register, call (231) 459-5569.