I bought the DCWV card sets and stamped and clear embossed the bat stamp which was a bargain at $1 at Michael's!
They are actually pens. The "stem" is a ballpoint pen and the cap is secured in foam in the ceramic pot base. I got the idea from my supervisor. I'm planning on trying to sell them at my table at the craft fair in a few weeks.
Before I start my day I wanted to post a quote I found years ago. I don't know the author - I found it looking for substance abuse and ACOA information at work. I need to keep it in mind today and thought others might find it helpful as well.
The colors...reds, oranges, golds, browns.
The Hammond Castle Haunted House..the absolute scariest thing I've ever been too!
Being inside, warm and cozy with a nice dinner on a cool, fall night.
Cooking comfort food like Corn Chowder, Beef Stew, Baked Chicken.
New Beginings. Some associate Spring or the New Year with fresh starts. For me it's fall.
Bought lots of mums, a cabbage plant, and some houseplants. The birdhouses I painted years ago.
After I went to the grocery store for a few things...apple cider included! My favorite treat this time of year is a mug of hot cider. Now I'm relaxing, ordering some pictures to be developed, roasting a chicken and just taking it easy before the busy week begins again.
Tonight...after the gym I hope I'm not too burnt out and tired so I can work on some cards. I really haven't had time and I have been antsy to burn off some creative energy this week. Unfortunately everything else of everyday life has taken priority. I told myself I wouldn't do that. Monday night I took an hour and did some drawing. But that's the only creative thing I've done in a week and a half. Unless you count putting together the microwave cart!
Over the past few days I've reconnected with some old friends and connections. Mainly through the internet. It really is amazing how you can so easily find and talk with people you have lost touch with through facebook, myspace, etc. I reconnected with my mentor - my high school art teacher. She was the one who introduced me to the idea of art therapy. She and her work inspire me greatly. I reconnected with an old friend from college who is from Venezuela, a friend from grad school who is from Taiwan and a local friend who interned where I work last year. Actually I reconnected with the last friend through the phone...but text messaging...which I am not good at! I'm amazed watching kids fly through the tiny keypad on their phone and type out detailed messages. It takes me 15 minutes to write two words!
My sister gave me this card for my birthday. Cracked me up! Love it. Even considering putting it in a little frame because it makes me laugh.
This magazine is a source of inspiration for me for my apartment, cards and layouts. I love the colors and ideas. Especially their fall issue. I also left the store with a 1/2 gallon of cider. I only went in for a dozen eggs! One of my favorite things about fall is relaxing with a cup of hot cider. Mmmm. I prefer the cider from our local apple orchard but I haven't made my first trip there yet. Maybe next weekend.
Well...off to read some blogs, my magazine and hopefully take some time working at my art "station!"
My vase of the sea lavender I mentioned in my last post. Not the greatest picture and it is hard to see the detail of the flower...tiny, purple...lacy.
Making Memories page kit from thier Passport collection. Thinking I want to use this kit as the basis for a mini board book of my summer. I have a small board book I've literally had for years and didn't know what I wanted to do with it. I think it'll be cute. Now...I need to decide on the pictures and get them ordered/printed.
I have so many half finished!
I will leave you with this funny picture of my birthday cake Cary made me...where he prematurely aged my with 39 candles. Yes 39. We are lucky the smoke detector didn't go off! It tastes yummy!!!
Thank you for all the "Happy Birthdays!" I really enjoy reading everyone's messages and seeing what is happening in your lives through your blogs. I plan on catching up on some of them this weekend.
I had a very nice birthday/week. For any Gilmore Girls fans, you know that Loralie Gilmore believed in celebrating your birthday for a full week...my favorite show and character and an advocate for "milking" your birthday...I'm all for that! Today I came home from work and Cary made me wait outside in the hall. He was lighting the candles on the cake he baked me today. Sweet. It was the first chance he had to make me one. Chocolate cake with chocolate frosting. Funny part was that he accidentally "aged" me by putting 39 candles on the cake instead of 31. He miscounted looking at the candle boxes! What a goof. But a sweet one! He plans on cooking his version of chicken parm tomorrow night. I can't wait...he's spoiling me and I will take it while it lasts!
Tonight I spent some time at my parents and took a very relaxing walk. Saw a little brown rabbit run right in front of me across the road. Breathed in the early fall smell in the air. Picked some "sea lavender" at the bridge. It is a wildflower that grows on the marsh by the creek/river and looks a little like dried lavender. I have always loved it. My grandmother always had some dried in her house. It hasn't been growing as much and this was the first time since I was a kid that I saw some where I could pick it. I will try and take a picture tomorrow. I love it!
It's my 31st birthday today! I can't believe it. 31. How did that happen? Time goes too fast. Looking forward to seeing Cary (hopefully) when he gets back later today...then he has to run off to work at 5:30. So I'll probably only see him for 15 minutes today if I'm lucky!
Tonight I'm going out for dinner with my parents and probably my sister. Looking forward to that!
Detail of a Chickadee card I made last weekend. This is one of my favorite little stamps. And my new favorite scalloped square punch. Friday I went out and bought a larger one!
After the trial of the flat tire...I have had a fantastic weekend! Cary was at guard so it is a little lonely without him but I had a chance to do lots of homey, relaxing stuff.
Cooked stuffed peppers and rice last night for my parents. This was the 1st time they've been over since the move. It was so nice to be with them and show them my space (almost) fixed up.
Grocery shopping. Oddly, a chore I enjoy. There is nothing better (I think) than having lots of good stuff in the cabinets.
Did a layout this morning and some fall cards.
Took a walk on the boulevard this afternoon. Nice breeze, lots of dogs playing in the water.
Treated myself to a mocha chip ice cream after my walk!
Read the newspaper out on the patio with the day being so beautiful. Unexpected given I was under the impression it was going to be rainy all day from the hurricane...but fortunately it passed through quickly (and relatively quietly) overnight.
Smelling a delicious mexican-like chicken soup cooking in my crock-pot. Love the smell. It was called "Tequila Chicken Soup" but I omitted the Tequila since I don't really like it. Still smells good! We'll see how it tastes later.
Watched/listened to episodes of my favorite show "The Gilmore Girls" while I worked on art stuff at my desk.
Vacuumed and cleaned up a little. Makes me feel content to have a clean house.
Well...that's all for now. I'll leave you with a few pictures of my creations for the day!
Layout I scraplifted from someone named Ashley Calder in an old issue of Creating Keepsakes I clipped out awhile ago.
Detail of the page. I loved the original layout...lots of interested layers and details. She used a lot of fabrics in the original. I used lots of ribbon and paper scraps and various tags I've collected. On the little white brad holding the "beautiful" tag I used a sharpie marker to make the polka dots...a fun little detail.
Another leaf card...this time played around with my two different sized scalloped square punches...used a copper paper and a taupe cardstock. Added another MM-Definitions sticker.
update from earlier post. feeling lucky.
I went to a garage and yes indeed...all the tires could have easily gone flat at any time. The valves were cracked on all of them. When I had my new tires put on at Sears 1 1/2 years ago they didn't replace the valves.
The guy at the garage took off one of the front tires, literally touched the valve on the wheel and the air gushed out of the tire.
He said it isn't unusual for many places to leave it up to the customer to decide about replacing the valves, etc when they get new tires. This garage doesn't do that. They add it into the service since most people don't know what all that even means.
Needless to say, I will be giving him my business the next time I need tires. He fixed all of my tires when he was getting ready to close for the day. He was pleasant and had excellent customer service. And he's local.
I'm feeling very grateful today.
Off to get ready to cook dinner for my parents in my new place.
So my day yesterday started on a very bad note.
I was driving into Boston. Nervous because I had my first class of the semester to teach at noon. I'm on 93S and a guy started making strange gestures to me in my rearview. I was thinking "What the heck?!" He kept doing it. Then a another woman did.
At that point I was in no position to pull over. I was at a stretch right before my exit that has no break down lane. So I took my exit for Storrow Drive and found a small peice of breakdown lane. Before and after where I stopped there is nothing. Traffic was backed up and I was freaking out! For anyone familiar with (a) Boston rush hour and (b) Storrow Drive...you know this was not a good setup. So I call AAA.
It is the best money I spend! They put me on a "priority list" because of my location...which by-the-way was difficult to explain to the dispatcher. Then I get a call from the state police trying to clarify where I was...they were not so friendly. Traffic started picking up again and cars were flying by me and then slamming on the brakes just ahead where the traffic was backed up. Fun. I am a worrier and a cryer. I was trying not to do both! The tow truck came and then 2 cops. They towed me to the end of the ramp where he could change my tire. I can change a tire but not under those circumstances! So...alls-well-that-ends-well. I got to school in time for class and it went ok.
A kind of odd/funny end to my day. Last night I'm sleeping and I was woken up in a wierd way. We have a big window at the head of our bed and a slider door in the living room. At night we keep both open to get a cross breeze. Our apartment is on the top floor and the complex is on a hill so we get some nice breezes/wind at night. Well...it was breezy and raining! I got rained on in my sleep! It was kind of funny!
maybe by some chocolates at my favorite chocolate shop!
Picture of me taken at the zoo a few weeks ago. The sign and the picture just fits me right now. Sarcastic? Obvious? Just need a little humor. I'm tired. Not feeling too much like writing. Full of mixed emotions. Heated "discussions" with someone I love, even when they turn out ok, make me tired and have no energy. So...instead I will try to focus on some positives...a gratitude list.
1. To have stated my opinion and asked that it be respected.
2. To have acknowledged changes I can make to how I respond to other's opinions.
3. That tomorrow is Friday and the first day of class.
4. That my birthday is on monday and I plan on getting a few small treats after work tomororw.
5. That I have food in the fridge and cabinets.
6. That I have my bills paid.
7. That tomorrow is payday.
8. That I have a nice, quiet, comfortable place to live.
9. That I have someone who loves me and whom I love back.
10. That I have nothing to do now except lie on the couch and watch TV and then get a much needed, good night sleep!
In my quest to enjoy the day-to-day, I am re-living my "youth." I'm all set and excited to watch the 2 hour season premiere of 90210 tonight.
Is anyone else feeling a little down about the end of summer?
Not really sure why. Why do I have to loose the feeling of summer just because the calendar says so? One thing I really want to work on changing about myself is living to get to the next day off. the next vacation. the next something. I really want to make an effort to enjoy the regular days. Work days. I always say I'd like to do this. It seems easy at the end of a long weekend or at the end of a relaxing vacation.
Not so easy in the middle of a crazy busy frustrated work day.
Sometimes I will put in a little treat to my day. An ice coffee. A gossipy magazine. A trip to the scrapbook store. But you can't do this everyday. That only touches the surface not the feeling underneath.
I read somewhere that it is important to schedule your next vacation the day you get back to work from a vacation. I did do this. Scheduled an extra day to extend Columbus Day Weekend. But that's more than a month away. And it avoids looking forward to tomorrow. Tuesday. Wednesday.


Thank you for the very good response to the homework survey we undertook during the Parents' Evenings in November. Pupils across P4-P7 were also surveyed.
We are now planning to introduce a new approach to home learning which will start from the week beginning Monday 28 January 2019. The new approach aims to consolidate learning and skills in literacy and numeracy and to give children opportunities to use their learning in real life situations such as home routines and community activities.
The school is planning for a drop in open event later this month for parents/carers to learn more about the new approach to home learning. See Over.


The ZX430i's ZX400i barcode printer series is produced to provide the highest level of commitment to retail, warehouse, logistics and transportation, government and administrative retail, and healthcare applications.
- Connector: USB2.0, USB host, serial and parallel port, Ethernet, optional WIFI & Bluetooth module for many applications.
- Memory: 32 MB SDRAM and 128 MB Flash memory - Includes 60 MB user memory.
- Print speeds up to 4 "/ 100 mm / sec.
- Supports bar code printing bar code of 450 meters and 8 inch diameter label (3 "core) available for bulk printing.
- Free GoLabel label design software.
- Use 450m rolls and 150m roll of paper to help users reduce the operation of changing accessories when printing, to avoid errors during the replacement.
- When printer or software issues we can support you by phone or teamview, not fix we will go to support.
In addition to supporting barcode printers, we can answer any questions you may have about barcodes.


text:
Chu Guangxi (, 706/707–760) was a Tang Dynasty poet.

Biography
Chu Guangxi was born in around 706 or 707, and was originally from Yan Province (modern-day Shandong Province).

In the last year of the Tianbao era he was appointed investigating censor (). He was implicated in the An Lushan Rebellion and exiled to Lingnan.

He died in .

Poetry
His surviving poems, such as "Mutong Ci" ( mù tóng cí) and "Diaoyu Wan" ( diào yú wān), are simple, elegant and pastoral.

Notes

References

Works cited

External links
Books of the Quan Tangshi that include collected poems of Chu Guangxi at the Chinese Text Project:
Book 136
Book 137
Book 138
Book 139

Tang dynasty poets
8th-century Chinese poets
707 births
760 deaths
Writers from Changzhou
Poets from Jiangsu
People from Jintan District

redpajama_set_name: RedPajamaWikipedia


text:
Andres describes how you don't have to think like everyone else to be valued at Pictet
"In the final interview I told them, I don't think I fit in, I think differently from you guys. 'That's exactly why we want you' came the reply."
Role: Co-head of Global Bonds, Pictet Asset Management, responsible for managing close to USD 9 Billion in Absolute Return, Global Bond and European Bond portfolios
Home country: Colombia
Hobbies: Tennis, skiing, travelling
Andres, Co-head of Global Bonds, Pictet Asset Management
Tell us about your home life
I'm surrounded by creative people. My wife has her own fashion brand-Paola Rodriguez, my father's an architect, my mother a lawyer and my sister's an artist. I'm the exception. I'm a numbers guy.
When I came in 2011 I was an outsider, far from a typical hire. In my interviews, whenever I said something, people disagreed. In the final interview I told them, I don't think I fit in, I think differently from you guys. 'That's exactly why we want you' came the reply. I was given a blank page to create a process and build a global bond business for Pictet.
Can you predict the market?
We don't believe in forecasting, so we concentrate on long term structural themes that we think will influence the market. Also for me, technicals are voodoo. A technical guy will stare at the screen and hope the charts will tell him what happens next. You need to focus on valuations.
Currently, our themes are, first, rates will stay low for longer; second, that Abenomics stays in place; third, the Euro crisis persists; and fourth, the Chinese transition from export-led to domestic growth continues. We're considering whether to add a fifth: the rise of populism and the end of globalisation.
We look for value within these long term structural themes and aim to build robust portfolios.
How do you see the mid-term future?
There will be more shocks in Europe. The EU doesn't have a transfer mechanism and no efficient banking union to recapitalize Italian banks. There's the French presidential election coming up, the Dutch election... the Eurozone was constructed at the end of the 80s and now the idea of a common market is being challenged, as is the idea of globalisation. Populism is spreading.
Do you rely on instinct or hard evidence?
I lost sleep many times because of the markets. When something is wrong, I feel it in my gut, no, in my back, here, and here. I feel, 'we need to do something!' It's a contrarian instinct, and now it's embedded in our process. I used to think my instinct was wrong - why do I want to buy when the market's down?
But you learn from experience. It's the most underrated commodity. My favourite motto is Mike Tyson's: everyone has a plan until they're punched in the mouth.

redpajama_set_name: RedPajamaCommonCrawl


text:
Redditor eats a vinyl record after Kendrick Lamar fails to drop a second album on Easter
Cousin Tyrone ground up a copy of an LP and mixed it into some ice cream
April 17, 2017 | 3:35pm ET
Following the release of Kendrick Lamar's DAMN. last Friday, the Internet immediately went into hyperdrive over the possibility that the Compton MC would be dropping a second album on Easter. The speculation was based on the fact that the first album was released on Good Friday (the day of Christ's crucification). Kendrick is murdered in the lyrics of DAMN., and there was prevailing thought was that, like Christ, he would resurrect on Easter with a second album. There was also speculation that the second album would be called NATION. (making the album's full title DAMNATION., get it?), and whereas the placement of the "M" on DAMN.'s cover sort of makes it look like Kendrick has devil horns, on the second album, he'd have an "O," like a halo.
And that was really just the beginning of the conspiracy theory. It was the sort of thing that made a whole lot of sense if you really wanted to believe it, but then you're brought back to the bowels of reality when Sunday comes and goes, there's no new album, and fucking Christ guys, just enjoy the excellent new album he gave you three days prior.
Seemingly never having heard of The King of Limbs Pt. 2, more than a few Redditors subscribed to the theory. One user named Cousin Tyrone was so convinced, he promised to eat a vinyl record in the event nothing was released. Well, with no NATION. being released, Cousin Tyrone has since made good on his promise, as he ground up a vinyl LP in a blender, mixed in some ice cream like a milkeshake, and took a few healthy spoonfuls. And because it's 2017, he of course filmed the whole thing and uploaded it to Internet.
In an accompanying message posted to reddit, Cousin Tyrone wrote:
"I took A LOT of laxatives to help pass the vinyl as fast as possible. It's been around 16 hours since I did this and I'm still feeling the effects of it.
Overall, I do not recommend eating vinyl. I'll answer more questions if you have any."
If this sort of thing sounds familiar, you may recall that Radiohead fans ate photos of Thom Yorke's face to celebrate the release of A Moon Shaped Pool last year. Fandom is truly weird.
Flower Lab Pre-Roll Sampler Pack


Since cricket features gained wonderful popularity across the world, cricket enthusiasts are seeking various solutions to update their know-how about this amazing game. Every several years hundreds cricket suits and events are organized and the wonderful enjoy these people by making your reservation for their passes for are living matches. But certainly not everyone could manage for this, hence, people check for an option that will keep these people informed with regards to every happening in the cricket terrain.
At found, n numbers of T. Versus. channels are generally providing those with the incredible facility to observe live cricket go with and the truth is, it can be somehow which allows cricket fans to find every glimpse with their favorite cricket legend. Moreover, not simply television nevertheless newspapers, radio and a lot of other transmission modes are offering to you best probable information for you to attract his or her listeners, readers and audience. Now with these every cricket enthusiast could get whatever information he / she need about her or his favorite sport. In a real scenario while every transmission mode is trying to find connected which consists of consumer group why is this internet can forgotten? In simple fact, internet is usually providing cricket supporters with on-line services along with tools to further improve their know-how about their favourite game. In addition, it is providing people using online credit standing so they really may get pleasure from every celebration through updated credit standing.
Cricket credit score definitely, offer the lucid along with precise specifics of any cricket match and they are sufficient enough to find out the reputation of just about any ongoing as well as played go with. Even men and women, who enjoy live cricket match watch the credit score board mainly because it help these people in credit reporting what happen in the last balled as well as stroke that they missed out and about while chatting on mobile phone or doing something more important. Websites that include cricket reports other solutions also keep its own section pertaining to cricket credit score, so that will their visitors may get updated specifics of any on-going match.
Since countless options can be purchased to have the desired specifics of cricket, men and women often find confused. On the other hand, every option is suitable and every bit as beneficial but in relation to getting current and easy information, every cricket fan prefer to view online cricket credit score. The major reason for choosing severe is their convenience along with availability, as on-line cricket details might be accessed when and through the comfort in your home or place of work. In simple fact, this method can present you with uninterrupted credit history details with no taking much time and attempts.
However, watching are living cricket has a unbeatable relevance, but since so many people are leading a new busy lifestyle nowadays, squeezing predefined timetable and taking a long time out pertaining to watching cricket is just not possible. In a real situation net and cricket websites can be the ideal available origin, as you'll be able to access these people without inside your schedule. You can even examine out cricket credit score through these kind of websites which enable it to assess the position of your selected team as well as player. The truth is, it is able to keep you current about every single happening in the cricket ground which enable it to keep anyone connected with no favorite game whenever.


text:
Jon Stewart on Palin children: 'Who gives a sh–t?'
Last night on the 'Daily Show,' Jon Stewart mocked media reports of the man that shot his TV because of Bristol Palin's performance on 'Dancing with the Stars' and the conspiracy theories behind Bristol Palin's longevity on the reality show.
"It's Bristol Palin! She's not running for anything. said Stewart, "She's not doing anything wrong. If you don't like how far she's going, don't watch the show."
Also rounding out the Palin coverage yesterday was a report on Willow Palin's controversial comments on her Facebook page.
"Stop making me feel sympathy for the Palins!" Stewart exclaimed, "It's a 16-year-old kid's Facebook page!"
"Kids are off-limits," Stewart pronounced, "As a matter of fact, we should all go out of our way to treat her children with kid gloves and respect to show that we don't judge individuals and mock them purely based on who their parents are."
But to prove that he wasn't about to let up on Sarah Palin, Stewart shot off several jokes at the expense of TLC's 'Sarah Palin's Alaska,' followed by a parody of the show with his correspondent Jason Jones.
Tags: Beltway Confidential, Jon Stewart, Sarah Palin, US


GREE Forum > Forums > Modern War > Off-Topic > What movies just came out?
View Full Version : What movies just came out?
What movies came out after August 1st I haven't really been paying attention.
movies come out at different time in different countries. I am in Hong Kong and there is 4 new movies came out after 1st of August.
I just watched White House Down yesterday, i must say that it was a good action/shooting movie. If you like to watch movies that involves lots of shooting and explosion then i highly recommend you to watch that movie.
The Heat is a comedy/action movie. If you are looking for a laugh, then simply watch this movie.
I found Wolverine quite disappointing.. i mean there was lots of actions.... but the story line was very short..


text:
#btconf Munich, Germany 04 - 06 Oct 2021
On this page you find all information concerning the venues, suggestions for hotels as well as a brief description about how to get to the conference. If anything is missing, or you have questions, please don't hesitate to contact us!
Muffatwerk (Conference, Main Event)
Originally, a single fountain house, securing the water supply for the neighbourhood named "Haidhausen," stood at the site of today's ensemble of buildings. It was constructed in 1837 by "Stadtbaurat" (planning director) and architect Franz Karl Muffat.
In 1973 the power station was shut down and nowadays, the former turbine hall of the hydropower station is housing "Muffathalle" and "Muffatcafé." The original boiler house built in Greek Revival style has been remodelled by a team of emerging architects and, today, accommodates the club "Ampere".
I think the venue fits the idea of beyond tellerrand and am totally happy to use this venue as new home for our Munich edition and hope the the known spirit and atmosphere of beyond tellerrand events will also be noticable here.
Muffatwerk
Zellstraße 4


Several of the names will likely be familiar, but 2015 Funko Pop Gotham presents an alternate view of Batman and his hometown. The set includes figures for Bruce Wayne and James Gordon from the popular television series.
Gotham tells the tale of Batman and Commissioner Gordon during their earlier years. Basically a prequel to the more-familiar story of Batman, many of the regular villains come into play as well.
The figures don't necessarily scream Batman, but they go along well with the theme of the show. In addition to figures for Wayne and Gordon, Oswald Cobblepot, who would become The Penguin, and Selina Kyle, also known as The Cat or Catwoman, are both included in the 2015 Funko Pop Gotham release. Cobblepot even displays his trademark umbrella.
Other options include Fish Mooney, a mobster played by Jada Pinkett Smith and Harvey Bullock. Bullock is James Gordon's partner on the police force.
Funko Pop Gotham is numbered as part of the Pop! Heroes line and the figures stand approximately 3 3/4".
FUNKO POP GOTHAM TV Series SELINA KYLE 4 inch pop VINYL FIGURE new!
FUNKO POP GOTHAM TV Series FISH MOONEY 4 inch pop VINYL FIGURE new!
FUNKO POP GOTHAM TV Series HARVEY BULLOCK 4 inch pop VINYL FIGURE new!
why no Edward nygma? losers.


MORRIS PLAINS, N.J. — Cushman & Wakefield has arranged the sale of a three-story office building in Morris Plains. The sales price was undisclosed. Located at 201 Littleton Road, the 88,910-square-foot property is set on a nearly 17-acre site. The property was 44 percent leased at the time of sale to a tenant roster that includes the State of New Jersey. Andrew Merin, Andrew Schwartz and Kubby Tischler of Cushman & Wakefield represented the seller, Mack-Cali Realty Corp., in the transaction. The buyer was Chopp Holdings, a local investor.


Doors are in and work!
If it helps anyone out, the name I needed to use for the doors with the plugin was FDOORSL301.
where do you even get zone files for Old Bazaar? As far as I understand they not even in Titanium client.


Bowral, New South Wales is a great place to hire a boat. You can hire or charter a small motorboat, sailboat, houseboat, or even a yacht. Take in the beautiful scenery and spend quality time with your friends and family while having the perfect day on the water. From birthday celebrations and stag or hens parties to family holidays, Bowral, New South Wales is the perfect boat hire destination.


The Software AOL Desktop Gold is an application which provides its users to access web browsing, send emails and web browsing and IM conversation. This application is a product of AOL which protect its users and provide them safe browsing options. The download option of AOL Gold Desktop is too easy because it's both new and old versions AOL Gold, AOL 7.0, AOL 9.7, AOL 9.8 and another browser of AOL are available for all users. If we compare the old version of AOL Gold with its new AOL Desktop Gold then they can find that new version of AOL Desktop Gold has improved performance, fresh look, and functions. Although it is very simple to use as before. If any user of AOL face problem to use its new version or have any quarry related to AOL Desktop Gold then just call on third party AOL Desktop Gold Support Number which is available for all AOL users every time. If anyone doesn't have AOL email account then they can use it as regular navigator.
To communicate with family and friends it provides instant messenger which send or receive a message within real time. Safe to the user and it keeps data of users secure always. For Windows 10 users it has a free download available like AOL Gold, AOL 9.8, AOL 9.7, 7.0 or new version AOL Desktop Gold. At the AOL Desktop, the Gold customer will get various links related to weather, news, sports, finance, TV etc. All users of AOL Desktop Gold can download tracker, AOL toolbar, parental control etc.
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How to fix when Yahoo sign in a page reload again and again?


It is once again Tuesday and we have just released the 179th batch of iPhone ringtones. If you are a subscriber they will all be available in your feed in iTunes by the time you read this as usual.
ring, ring it's your phone ok..
It is once again Tuesday and we have just released the 178th batch of iPhone ringtones. If you are a subscriber they will all be available in your feed in iTunes by the time you read this as usual.
It is once again Tuesday and we have just released the 177th batch of iPhone ringtones. If you are a subscriber they will all be available in your feed in iTunes by the time you read this as usual.


text:
Study Helps Explain Inhibition of MRSA by Manuka Honey
Effect of Manuka Honey on the Expression of Universal Stress Protein A in Meticillin-Resistant Staphylococcus aureus
Int J Antimicrob Agents, 2011 Feb 22
Staphylococcus aureus is an important pathogen that can cause many problems, from impetigo to endocarditis. With its continued resistance to multiple antibiotics, S. aureus remains a serious health threat.
Honey has been used to eradicate meticillin-resistant S. aureus (MRSA) strains from wounds, but its mode of action is not yet understood.
Proteomics provides a potent group of techniques that can be used to analyse differences in protein expression between untreated bacterial cells and those treated with inhibitory concentrations of manuka honey.
In this study, two-dimensional (2D) electrophoresis was combined with matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry (MALDI-TOF MS) to determine the identities of proteins whose levels of expression were changed at least two-fold following treatment with manuka honey.
Protein extracts were obtained from cells grown in tryptone soy broth (with or without manuka honey) by mechanical disruption and were separated on 2D polyacrylamide gels. A protein was isolated in gels prepared from untreated cell extract that was absent from gels made using honey-treated cell extract. Using MALDI-TOF MS, the protein was identified as universal stress protein A (UspA).
Downregulation of this protein was confirmed by real-time polymerase chain reaction (PCR), which showed a 16-fold downregulation in honey-treated cells compared with untreated samples.
This protein is involved in the stress stamina response and its downregulation could help to explain the inhibition of MRSA by manuka honey.
Honey Has Antibacterial Activity Similar to Antibiotics
Antibacterial Efficacy of Raw and Processed Honey
Biotechnol Res Int, 2011:917505
In vitro antibacterial activity of methanol, ethanol, and ethyl acetate extracts of raw and processed honey was tested against Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Enterococcus faecalis, and Micrococcus luteus) and Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa, and Salmonella typhi).
Both types of honey showed antibacterial activity against tested organisms with the zone of inhibition (ZOI) ranging from 6.94 to 37.94 mm, while E. coli, S. typhi, and P. aeruginosa showed that sensibility towards all the extracts with ZOI ranges between 13.09 to 37.94 mm.
The methanol extract showed more potent activity than other organic extracts. Gram-negative bacteria were found to be more susceptible as compared to Gram-positive bacteria except E. faecalis. The broth microdilution assay gave minimum inhibitory concentrations (MIC) value of 625 μg/mL, while the minimum bactericidal concentration (MBC) ranges between 625 μg/mL 2500 μg/mL.
The study showed that honey has antibacterial activity (bacteriostatic and bactericidal effect), similar to antibiotics, against test organisms and provides alternative therapy against certain bacteria.
Report on First Hungarian Apitherapy Congress
Dr. János Körmendy-Rácz President of the Hungarian Apitherapy Society
Some 240 people attended the first Hungarian Apitherapy Congress in Budapest, the birth city of Dr. Bodog Beck. The congress was organized by the Hungarian Beekeeper's Organization and the Hungarian Apitherapy Society. Although there is a great tradition of apitherapy in Hungary, no conference has been held until today - concluded one of the speakers. Fifteen speakers showed the results of the current apitherapy research. The themes included all beehive products from honey, propolis, bee venom, pollen, to royal jelly.
Tibor Erdélyi spoke about the research results of over 50 year work of Professor Szalay, who was the author of multiple books on apitherapy. He was planning to give a lecture, but he died just before the conference.
Dr. Anna Mária Nagy spoke about the treatments using royal jelly. The specialist of diseases of internal organs has been treating autoimmune diseases with royal jelly for 10 years. Fifteen cases were presented.
Dr. Éva Szabó, assistant professor from the University of Debrecen treats wounds with honey. The presented three cases were in the area of difficult healing wounds, e.g. diabetic foot.
Live bee sting treatment on acupunctural points was shown by István Gillich and his colleague Zita Pataki.
Two theoretical lessons were given by experts of the field: István Gillich spoke about his experience of 14 years of treating multiple sclerosis with bee sting therapy.
Kálmán Debreceni spoke about his research results: steps to digest pollen over 90 percent. Royal Jelly was mentioned again.
Ingredients and storing conditions were the theme of Dr. Péter Sebők's presentation.
Dr. Ágnes Farkas, assistant professor from the University of Pécs raised a question: Which medical plant has connection to its honey? Detailed laboratory work was presented.
The Chief-Pharmacist Dr. Ágnes Soltész showed some results with her own ointments, pills, drops, sprays. The presented cases were from the area of wound healing.
Tamás Kutasi is a master beekeeper. He is dealing with the practice of producing apitherapy products.
Dr. János Körmendy-Rácz, the president of the Hungarian Apitherapy Society spoke about a case study: treating breast cancer with propolis suspension, APYS® bee venom ointment and royal jelly. The presented case is an 80-year-old woman with scheduled date to chemotherapy. She began the propolis and bee venom treatment, and fast changes were detected. After 15 months gentle treatment she is very well, almost all signs disappeared completely.
Ibolya Rudolf, cosmetician tutor, and Anikó Albert cosmetician observed the effects of APYS® bee venom ointment in facial skin care. They presented the pictures of female faces before and during the treatment. The treatment is still in progress, but the first two week's results are very promising.
For more information, contact Dr. János Körmendy-Rácz at email: krj@apiterapia.hu
Manuka Honeys Might Reduce Pathogens Within Dental Plaque
The in vitro Effect of Manuka Honeys on Growth and Adherence of Oral Bacteria
Anaerobe, Volume 17, Issue 1, February 2011, Pages 19-22
Honey has been used since ancient times and more recently, for the healing of wounds and against infectious diseases. The aim of our study was to investigate the effect of two manuka honeys showing different potencies of their antibacterial activity, on potentially pathogenic oral bacteria.
The antimicrobial activity was examined by determining the MIC and MBC using the macro dilution broth technique. The effect on the adherence was tested on growing cells of Streptococcus mutans on a glass surface and on a multi-species biofilm grown on saliva-coated hydroxyapatite discs.
As expected, the antibacterial activity of manuka (with higher potency of antibacterial activity) was the most important. The two tested honeys weakly inhibited the adherence of S.mutans cells to a glass surface at sub-MIC concentration.
Manuka showed a total inhibition of multi-species biofilm at the concentration of 200 μg/ml manuka inhibited biofilm formation weakly at the concentration of 200 μg/ml but firmly at the concentration of 500 μg/ml.
Our findings suggest that manuka honeys might be able to reduce oral pathogens within dental plaque. These two honeys appear to be able to control dental biofilm deposit.
Honey May Help Reduce Damage to Diabetic Kidneys
Comparison of Antioxidant Effects of Honey, Glibenclamide, Metformin, and Their Combinations in the Kidneys of Streptozotocin-Induced Diabetic Rats
Int J Mol Sci, 2011 Jan 21;12(1):829-43
Hyperglycemia-induced increase in oxidative stress is implicated in diabetic complications.
This study investigated the effect of metformin and/or glibenclamide in combination with honey on antioxidant enzymes and oxidative stress markers in the kidneys of streptozotocin (60 mg/kg; intraperitoneal)-induced diabetic rats.
Diabetic rats were randomized into eight groups of five to seven rats and received distilled water (0.5 mL); honey (1.0 g/kg); metformin (100 mg/kg); metformin (100 mg/kg) and honey (1.0 g/kg); glibenclamide (0.6 mg/kg); glibenclamide (0.6 mg/kg) and honey (1.0 g/kg); metformin (100 mg/kg) and glibenclamide (0.6 mg/kg); or metformin (100 mg/kg), glibenclamide (0.6 mg/kg) and honey (1.0 g/kg) orally once daily for four weeks.
Malondialdehyde (MDA) levels, glutathione peroxidase (GPx) and superoxide dismutase (SOD) activities were significantly elevated while catalase (CAT) activity, total antioxidant status (TAS), reduced glutathione (GSH), and GSH:oxidized glutathione (GSSG) ratio was significantly reduced in the diabetic kidneys. CAT, glutathione reductase (GR), TAS, and GSH remained significantly reduced in the diabetic rats treated with metformin and/or glibenclamide.
In contrast, metformin or glibenclamide combined with honey significantly increased CAT, GR, TAS, and GSH.
These results suggest that combination of honey with metformin or glibenclamide might offer additional antioxidant effect to these drugs. This might reduce oxidative stress-mediated damage in diabetic kidneys.
Propolis Effective as Root Canal Disinfectant
Antibacterial Activity of Propolis versus Conventional Endodontic Disinfectants Against Enterococcus faecalis in Infected Dentinal Tubules
J Endod, 2011 Mar;37(3):376-81
Introduction: The antibacterial activity against Enterococcus faecalis of 2 propolis samples was investigated in a dentin block model, and their effectiveness was compared with that of established endodontic disinfectants, chlorhexidine (CHX) and calcium hydroxide [Ca(OH)(2)].
Methods: Standardized dentin blocks were infected with E. faecalis ATCC 29212. The root canal space was filled with one of the ethanolic extracts of propolis (Artvin or Tekirdağ mix [TM]), CHX 2%, Ca(OH)(2), or ethanol or phosphate-buffered saline for control. Canal dentin was sampled after 1 or 7 days by using a standard-size bur. The dentinal shavings were vortexed vigorously in phosphate-buffered saline, and aliquots were cultured on tryptone soy agar plates. Colonies were counted after 2 days of incubation. Statistical significance was set to 5%.
Results: All experimental agents significantly reduced the number of the cultivable bacteria. CHX was the most potent disinfectant at both times. Compared with the ethanol control, no significant reduction in the number of colonies was found for the propolis extracts at day 1; however, significant reduction was found at day 7. The 2 propolis samples were statistically similar to each other and to Ca(OH)(2), but the TM sample was also similar to CHX at day 7. This has been linked to the greater concentration of flavonoids, a group of antibacterially active compounds, in the TM sample as determined by gas chromatography-mass spectrometry analysis.
Conclusions: The antimicrobial activity of the propolis samples tested in this study was between Ca(OH)(2) and CHX. Both propolis samples were antimicrobially effective; however, their activity did not exceed CHX.
Killing Cancer Cells with Bee Venom
PBS, 2/17/2011
The sharp pain of a honeybee sting is caused in part by a peptide called melittin, which kills cells by piercing holes in their membranes. To turn this indiscriminate killer into a fine-tuned cancer drug, researchers have combined it with nanoparticles and cancer-targeting agents that allow the melittin to "sting" cancer cells without harming healthy cells. Though the treatment has not yet been tested on human patients, it has shown promise on mice. Researchers also hope to harness melittin's cell-killing power to knock out other diseases, including bacterial and fungal infections and arthritis.
Sidr Honey Helps Protect Liver from Damage by Toxins
Dietary Honey and Ginseng Protect Against Carbon Tetrachloride-Induced Hepatonephrotoxicity in Rats
Experimental and Toxicologic Pathology, Article in Press
Liver diseases are amongst the most serious health problems in the world today and hepatocellular carcinoma is one of the world's deadliest cancers.
The aim of the current study was to evaluate the protective effect of sider honey and/or Korean ginseng extract (KGE) against carbon tetrachloride (CCl4)-induced hepato-nephrotoxicity in rat.
Eighty male Sprague-Dawley (SD) rats were allocated into different groups and over a 4-week period, they orally received honey and/or KGE or were treated either with CCl4 alone (100 mg/kg b.w) or with CCl4 after a pretreatment period with honey, KGE or a combination of both. Clinical, clinico-pathological and histopathological evaluations were done and CCl4-treated groups were compared with rats receiving no treatment and with rats given honey, KGE or a combination of these substances.
The results indicated that oral administration of CCl4 induced severe hepatic and kidney injury associated with oxidative stress. The combined treatment with CCl4 plus honey and/or KGE resulted in a significant improvement in all evaluated parameters. This improvement was prominent in the group receiving CCl4 after combined pretreatment with honey and KGE.
Animals receiving honey and/or KGE (without CCl4-treatment) were comparable to the control untreated group. It could be concluded that honey and KGE protect SD rats against the severe CCl4-induced hepatic and renal toxic effects.
Our results suggest that the protective activity of honey and KGE may have been related to their antioxidant properties.
Beeswax Component Has Anti-Inflammatory, Pain-Killing Effect
Evaluation of Anti-Inflammatory and Antinociceptive Effects of D-002 (Beeswax Alcohols)
J Nat Med, 2011 Jan 22
D-002, a mixture of six higher aliphatic alcohols purified from beeswax, displayed anti-inflammatory effects in carrageenan-induced pleurisy and cotton pellet granuloma in rats.
The aim of the present study was to confirm the anti-inflammatory properties of D-002 and to explore its potential analgesic effects…
This study confirmed the anti-inflammatory effects of D-002 and demonstrated its analgesic effects on the acetic acid-induced writhing, but not on the hot plate response, which suggests that the antinociceptive effects of D-002 could be related to its anti-inflammatory activity.
Today in California: "Medicine from the Hive" - Fifth Annual Bee Symposium 2011
For Information, Go To: http://beekind.com/
"Bee Venom Therapy, Historical Perspective into Modern Applications"
(Dr. Frederique Keller)
"The Revolutionary Effects of Honey on Human Metabolism"
Dr. Ron Fessenden)
"Socialized Medicine in Honey Bee Colonies"
(Dr. Marla Spivak)
"Medicinal Use of Raw Honey, Pollen, Propolis, Royal Jelly, Bee Bread & Beeswax" (Dr. Frederique Keller)
"How to Sleep Your Way to Better Health with Honey"
(Dr. Ron Fessenden)
"Bee Health and Breeding"
Bee Pollen Hydrolysates Possess High Antiradical Scavenging Activity
Preparation of Antioxidant Enzymatic Hydrolysates from Honeybee-Collected Pollen Using Plant Enzymes
Enzyme Res, 2011 Jan 9;2010:415949
Enzymatic hydrolysates of honeybee-collected pollen were prepared using food-grade proteinase and aminopeptidases entirely of plant origin.
Bromelain from pineapple stem was applied (8 mAU/g substrate) in the first hydrolysis stage. Aminopeptidase (0.05 U/g substrate) and proline iminopeptidase (0.03 U/g substrate) from cabbage leaves (Brassica oleracea var. capitata), and aminopeptidase (0.2 U/g substrate) from chick-pea cotyledons (Cicer arietinum L.) were involved in the additional hydrolysis of the peptide mixtures.
The degree of hydrolysis (DH), total phenolic contents, and protein contents of these hydrolysates were as follows: DH (about 20-28%), total phenolics (15.3-27.2 μg/mg sample powder), and proteins (162.7-242.8 μg/mg sample powder), respectively.
The hydrolysates possessed high antiradical scavenging activity determined with DPPH (42-46% inhibition).
The prepared hydrolysates of bee-collected flower pollen may be regarded as effective natural and functional dietary food supplements due to their remarkable content of polyphenol substances and significant radical-scavenging capacity with special regard to their nutritional-physiological implications.
Recombinant Royal Jelly Peptide Exhibits High Antibacterial Activity
Facilitative Production of an Antimicrobial Peptide Royalisin and its Antibody Via an Artificial Oil-Body System
Biotechnol Prog, 2011 Jan;27(1):153-61
Royalisin found in the royal jelly of Apis mellifera is an antimicrobial peptide (AMP). It has a molecular weight of 5.5 kDa, which contains six cysteine residues.
In this study, royalisin was overexpressed in Escherichia coli AD494 (DE3) as two oleosin-fusion proteins for preparation of its antibodies and functional purification. The recombinant royalisin, fused with oleosin central hydrophobic domain in both N- and C-termini, was reconstituted with triacylglycerol and phospholipids to form artificial oil bodies (AOBs). The AOBs were then purified to raise the antibodies.
These antibodies could recognize both the native and recombinant royalisins, but not oleosin. Another oleosin-intein S-fusion protein was purified by AOBs system, and royalisin was subsequently released from the AOBs through self-splicing of the intein.
The recombinant royalisin exhibited high antibacterial activity, which suggested that it was refolded to its functional structure. These results demonstrated that AOBs system is an efficient method to functionally express and purify small AMPs. In addition, it also provides a facile platform for the production of antibodies against small peptides.
Propolis Paste Suitable for Root Canal Dressings
Removal Efficiency of Propolis Paste Dressing from the Root Canal
J Appl Oral Sci, 2010 Dec;18(6):621-4.
OBJECTIVES: The aim of this study was to investigate through scanning electron microscopy (SEM) the cleaning of root canal walls after the use of experimental propolis or calcium hydroxide root canal dressings.
MATERIAL AND METHODS: Twenty single-rooted teeth were used. After conventional cleaning and shaping procedures and removal of the smear layer with 17% EDTA, the teeth were divided into four groups according to the medication used (N=5): Group I (control) - No drug, Group II - Calcium hydroxide dressing, Group III - Propolis paste A70D and Group IV - Propolis paste D70D. The medications were introduced into the root canals and maintained for 7 days, then removed with a K-file and 5 mL of 1% sodium hypochlorite irrigation. Finally, the canals were flushed with 2 mL of 17% EDTA for 3 min. For SEM analysis, the roots were cleaved and microphotographs from the middle third of the root canal were taken at 750x. The cleaning of the root canal walls was determined by the number of open dentinal tubules as verified with the software Image Tool 3.1. The statistical analysis was performed by ANOVA and Tukey's test.
RESULTS: The results showed no statistically significant difference between the calcium hydroxide and propolis groups.
CONCLUSIONS: The experimental propolis pastes presented acceptable physical characteristics to be used as intracanal medicaments.
Lower Cost Food Honey as Effective as Medicinal Honey
Honey in Otorhinolaryngology: When, Why and How?
Eur Ann Otorhinolaryngol Head Neck Dis, 2011 Feb 8
In this review of the literature devoted to the use of honey, the authors analyse the composition, indications, benefits and adverse effects of this product in otorhinolaryngology and head and neck surgery.
Published data indicate that honey applied topically to skin and mucosal wounds and/or burns and administered orally as antitussive medication (after the first year of life) is highly effective with no adverse effects.
The physiological action of honey is the result of various mechanisms (osmotic, detersion, bactericidal action). Various medicinal honeys are available worldwide, but only one has Food and Drug Administration approval for the treatment of wounds.
After the first year of life, the use of food honey appears to be as effective as medicinal honey, while decreasing the overall cost of treatment.
Apitherapy Conferences and General Assembly of the Francophone Apitherapy Association to be Held in Lyon May 17
One-day experience exchange that focuses on health benefits of bee hive products
Internationally-known experts on "Apitherapy", the therapeutic use of bee hive products, will offer four conferences in Lyon, France, on Saturday, May 17, as an overview of the health benefits provided by honey, propolis, bee-collected pollen, beeswax, drone larvae extract, bee venom and royal jelly.
On the same day it will be held the General Assembly of the Francophone Apitherapy Association.
More details in http://www.apitherapie-francophone.org/
Indian Honey Entrepreneur Seeks to Expand Apitherapy Business
Ritu Kapoor's Sweet Success
By Neeta Lal, The Star (Malaysia), 2/12/2011
Young entrepreneur Ritu Kapoor, scion of one of the world's largest honey-exporting family businesses, is as busy as a bee with her frenetic expansion plans…
The young businesswoman's interest in honey, she says, began as a child. She would watch in fascination as her parents incorporated the golden-hued liquid into everything from food to face packs to home remedies.
"For burns, cuts, wounds, etc, my father would instinctively reach out for honey," recalls Kapoor. "In fact, I don't remember ever popping pills for minor ailments like today's kids. Daddy told me about honey's anti-bacterial properties when I was small and it has now became a part of my survival kit. Often, I help cure my friends' colds and coughs by putting them on a ginger-honey concoction."
According to Kapoor, the benefits of honey go beyond its great taste. "In Europe, men and women use honey to rejuvenate their skin," says Kapoor. "Unfortunately, in India, honey's many qualities remain untapped."
To plug that gap, the head of KA's business re-engineering programme is now planning to produce honey-based cosmetics and spa treatments. She is promoting honey for its wellness, beauty and health properties by tying up with spas and wellness centres across the country…
The company's plans include exporting to 100 countries by this year and marketing high-value byproducts like royal jelly and bee venom…
Video: Apitherapy for Health and Beauty
Honey Popular in Skin Care Products
Honey, I Love You It's sweet to taste and an equally sweet treat for the skin
Bangkok Post, 2/12/2011
Honey has long been used to pamper the skin, thanks to its cleansing, anti-oxidant and anti-microbial properties. In addition to that, the sticky stuff leaves a coat of film on the skin to lock in moisture and radiance. What's not to love?
Honey is an ideal skin care ingredient as it prevents drying. It also helps protect the skin from sun damage. This is why many skincare products, and even cosmetics, which are aimed at softening and moisturising the skin, use the benefits of honey to deliver an amazing fragrance and deliciously soft skin.
Its powerful healing properties are also second to none. Honey not only fights infection and aids tissue healing, but also helps reduce skin inflammation and scarring.
Honey can work as a facial mask, or along with other home remedies. Most commonly, honey is best friends with milk, both for health foods and for skin treatments. A glass of milk with a few drops of honey can help you sleep better at night, while a milk and honey facial mask can be a very good acne fighter.
Other acne remedies include honey with apple, honey with aloe vera, honey with tea tree oil, honey with cucumber and honey with aspirin. Yes, aspirin! This is probably the least delicious sounding recipe for the skin, but aspirin is a good skin conditioner that works well in treating acne in oily skin, and the coarse texture is great for exfoliation. It is not suitable for dry skin as it might cause excessive dryness and skin flaking.
Sometimes benefits of honey come in other various forms, such as propolis, royal jelly, beewax and bee pollen. These are also packed with honey's goodness but differ in form and concentration. For example, royal jelly is a honey bee secretion commonly found in adult queens. It is widely praised for its cholesterol-lowering, anti-inflammatory, wound-healing and antibiotic effects…
Propolis Component May Help Prevent Skin Aging
Inhibition of Stromelysin-1 by Caffeic Acid Derivatives from a Propolis Sample from Algeria
Planta Med, 2011 Feb 8
Stromelysin-1 (matrix metalloproteinase-3: MMP-3) occupies a central position in collagenolytic and elastolytic cascades, leading to cutaneous intrinsic and extrinsic aging.
We screened extracts of a propolis sample from Algeria with the aim to isolate compounds able to selectively inhibit this enzyme.
A butanolic extract (B (3)) of the investigated propolis sample was found to potently inhibit MMP-3 activity (IC (50) = 0.15 ± 0.03 µg/mL), with no or only weak activity on other MMPs. This fraction also inhibited plasmin amidolytic activity (IC (50) = 0.05 µg/mL) and impeded plasmin-mediated proMMP-3 activation. B (3) was fractionated by HPLC, and one compound, characterized by NMR and mass spectroscopy and not previously identified in propolis, i.e., (+)-chicoric acid, displayed potent IN VITRO MMP-3 inhibitory activity (IC (50) = 6.3 × 10 (-7) M).
In addition, both caffeic acid and (+)-chicoric acid methyl ester present in fraction B (3) significantly inhibited UVA-mediated MMP-3 upregulation by fibroblasts.
Apitherapy in Nicaragua
Familia marquense impulsa apiterapia
Prense Libre, 2/10/2011
Treinta años de producción de miel de alta calidad para exportación han dado a los propietarios del apiario Flores Occidentales, de San Marcos, la experiencia para impulsar la apiterapia como una alternativa contra algunas enfermedades.
Teodoro Miranda, impulsor del proyecto, indicó que ante la necesidad de la población comenzaron a producir algunos derivados de la miel y la colmena, como alternativas curativas.
Explicó que en la actualidad procesan polen, jalea real y propóleo, con los que se hacen combinaciones con plantas medicinales que dan como resultado jarabes para el tratamiento de enfermedades respiratorias…
Propolis Reduces Complications of Cancer Treatment
Effect of Propolis Against Radiation-Induced Oral Mucositis in Rats
Kulak Burun Bogaz Ihtis Derg, 2011 Jan-Feb;21(1):32-41
Objectives: This study aims to investigate whether propolis has a protective role in oral mucosal damage induced by radiotherapy applied to head-neck region, using quantitative, biochemical and histopathological approaches.
Materials and Methods: Forty eight Wistar-Albino adult female rats at eight weeks of age and weighing 213±27 grams were included in this study and randomly divided into six groups: Group 1: control, group 2: only irradiated rats, group 3: irradiated rats with propolis administration at 50 mg/kg/day, group 4: irradiated rats with propolis administration at 100 mg/kg/day, group 5: only propolis administration at 50 mg/kg/day, group 6: only propolis administration at 100 mg/kg/day. The first dose of propolis was administered before 30 minutes irradiation and the other doses after irradiation once daily for seven days by topical application. Radiotherapy was applied to the total cranium by single fraction at a dose of 18 Gy. The mucositis degrees and body weights of the animals were measured throughout the experiment. On the 7th day of study, blood samples were taken from the rats under ketamine anesthesia and then the rats were sacrificed and tongue tissues samples were taken. Complete blood count and biochemical and antioxidant activities were analysed in the blood samples. The tongue samples were microscopically examined.
Results: Radiotherapy group had a decrease in body weight and neutrophil count, and an increase in oral mucositis as compared with the control group. Moreover, an increase in plasma malondialdehyde concentrations and significant decreases in catalase and superoxide dismutase activities were observed in irradiation-alone group when compared to the control group. Propolis administered irradiated rat groups showed a dose-dependent normalization in quantitative, biochemical and histopathological parameters when compared with the irradiation-alone group.
Conclusion: The results showed that propolis is effective in reducing the severity of oral mucositis induced by head-and-neck irradiation.
Honey-Based Diet Promotes Lower Weight Gain
Honey Promotes Lower Weight Gain, Adiposity, and Triglycerides Than Sucrose in Rats
Nutrition Research, Volume 31, Issue 1, January 2011, Pages 55-60
Various dietary carbohydrates have been linked to obesity and altered adipose metabolism; however, the influences of honey vs common sweeteners have not been fully explored.
We hypothesized that in comparison with sucrose, a honey-based diet would promote lower weight gain, adiposity, and related biomarkers (leptin, insulin, and adiponectin) as well as a better blood lipid profile.
Thirty-six male Sprague-Dawley rats (228.1 ± 12.5 g) were equally divided by weight into 2 groups (n = 18) and provided free access to 1 of 2 diets of equal energy densities differing only in a portion of the carbohydrate. Diets contained 20% carbohydrate (by weight of total diet) from either clover honey or sucrose. After 33 days, epididymal fat pads were excised and weighed, and blood was collected for analyses of serum concentrations of lipids, glucose, and markers of adiposity and inflammation.
Body weight gain was 14.7% lower (P ≤ .05) for rats fed honey, corresponding to a 13.3% lower (P ≤ .05) consumption of food/energy, whereas food efficiency ratios were nearly identical. Epididymal fat weight was 20.1% lower (P ≤ .05) for rats fed honey. Serum concentrations of triglycerides and leptin were lower (P ≤ .05) by 29.6% and 21.6%, respectively, and non–high-density lipoprotein cholesterol was higher (P ≤ .05) by 16.8% for honey-fed rats.
No significant differences in serum total cholesterol, high-density lipoprotein cholesterol, adiponectin, C-reactive protein, monocyte chemoattractant protein-1, glucose, or insulin were detected.
These results suggest that in comparison with sucrose, honey may reduce weight gain and adiposity, presumably due to lower food intake, and promote lower serum triglycerides but higher non–high-density lipoprotein cholesterol concentrations.
Algerian Propolis Extract has Antioxidant Capacity
In vitro Evaluation of Antioxidant Capacity of Algerian Propolis by Spectrophotometrical and Electrochemical Assays
International Journal of Pharmacology, 2011 | Volume: 7 | Issue: 1 | Page No.: 113-118
The aim of the present study was to evaluate the antioxidant capacity and the total phenolic content of propolis extract, obtained from colonies of honeybees located in El-Oued (south of Algeria).
The total phenolic content was evaluated using the Folin-Ciocalteu method and the antioxidant capacity was measured using the following methods: 2, 2-diphenyl-1-picryhydrazyl free radical scavenging capacity and reducing power capacity for spectrophotometrical techniques, ascorbic and gallic acids equivalent antioxidant capacity assays for electrochemical techniques. Both techniques allowed an evaluation of the antioxidant capacity of methanolic propolis extract.
The electrochemical techniques were performed by cyclic voltammetry, the results suggest that propolis extract do not reveal similar electrochemical responses to that of ascorbic and gallic acids, suggesting a different electroactive chemical composition and oxidation potential more positive than that of the standard (ascorbic acid), however this does not suggest that propolis has a lower antioxidant capacity.
The results suggest also that propolis extract possess antioxidant capacity in vitro conditions.
New Propolis Extract Dissolves in Water, Retains Healing Properties
Bradford University Research Harnesses the Healing Powers of Honey Bee ResinTelegraph & Argus, 2/7/2011
Researchers at the University of Bradford have developed a way of harnessing the healing powers of propolis – a mixture of resin and wax made by honey bees.
The benefits of propolis in medicine and food supplements has been known for many years, but its use has been limited because the sticky substance is not water soluble and has a strong smell which is off-putting.
Now the university's Centre for Pharmaceutical Engineering Science has developed a way of purifying propolis that retains its medicinal properties, but makes it dissolve in water and gets rid of its pungent smell…
How to Use Propolis for Arthritis
Livestrong, 2/3/2011
Propolis is a type of resin that bees use to construct and strengthen their hive. This versatile substance has also been used for centuries as a treatment for inflammation, pain and compromised immunity. These effects are a result of the combination of resin and plants the bees use to make propolis. Propolis is generally regarded as safe to use and its anti-inflammatory effects can help reduce the pain and inflammation associated with arthritis. Speak with your doctor before using any remedy for pain and inflammation.
Discuss your intentions of using propolis with your physician. Although it is considered relatively safe to use, propolis may cause a reaction in people who are allergic to bees or pollen. It's also unlikely that propolis will cause an interaction with any medications you are currently using, but you still should discuss using this supplement with your doctor.
Apply a topical cream that contains propolis extract, available at your local health food store. Use the cream as directed by the manufacturer to help reduce the inflammation caused by arthritis. A 2007 article published in the "Journal of Venom and Animal Toxins" explains that propolis is an inexpensive yet effective topical treatment for both acute and chronic inflammatory processes such as arthritis. Propolis is particularly useful for treating these conditions when they occur in the joints between bones, where arthritis often appears…
Propolis Extract Protects Against UVA Radiation
The Use of Nanoemulsions Based on Aqueous Propolis and Lycopene Extract in the Skin's Protective Mechanisms Against UVA Radiation
Journal of Nanobiotechnology, 4 February 2011
The use of natural products based on aqueous extract of propolis and lycopene in the skin's protective mechanisms against UVA radiation was evaluated by means of experimental acute inflammation on rat paw edema.
The purpose of the study is the evaluation of the inoffensiveness of the propolis lycopene system, by evaluating skin level changes and anti-inflammatory action.
The regenerative and protective effect of the aqueous propolis and lycopene extract is due to the fact that it is rich in biologically active substances: tocopherols, flavonoids, amino acids, polyunsaturated fatty acids, the chlorophyll pigment, which are substances with a strong antioxidant action, that contribute to the modification of oxidative stress, especially by reducing the prooxidant processes and enhancing the antioxidant ones.
They participate in the synthesis of the prostaglandins and phospholipids composing the cell membranes and thus enhance the protection mechanisms in the skin. The formulated systems offered a sustained release of the drug, in vitro, for a time period of eight hours. The formulations that were prepared did not have a deteriorating effect on the tissues. They proved a better therapeutic efficiency compared to the standard suspension, because they were superior in improving the monitorized parameters for a longer period of time (24 hours).
The preliminary examination of the tissues shows that the formulations did not produce irritations. The local application of the aqueous propolis and lycopene extract nanoemulsion has a high potential both regarding its efficiency (the analgesic effect) and therapeutic safety. This research demonstrates the fact that the aqueous propolis and lycopene extract nanoemulsions, which are preparations that contain active substances, can confer better therapeutic effects than those of the conventional formulations, because of the local controlled-release of the dozed form, in a longer period of time, which may lead to an improvement of its efficiency and to the skin accepting it more easily, meaning a better compliance.
The information gathered in the present research suggests that the administration of aqueous propolis and lycopene extract nanoemulsion be safe and inoffensive. The preparation can be recommended for further preclinical studies. Lycopene embedded in aqueous propolis extract can be used in pharmaceuticals (targeted medical therapy).
Brazilian Green Propolis Boosts Prostate Cancer Cell Death
Ethanolic Extract of Brazilian Green Propolis Sensitizes Prostate Cancer Cells to TRAIL-Induced Apoptosis
Int J Oncol, 2011 Feb 1
Prostate cancer represents an ideal disease for chemopreventive intervention.
Propolis possesses immuno-modulatory, anti-tumour and chemopreventive properties. The tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is an important endogenous anti-cancer agent that induces apoptosis selectively in tumour cells. However, some cancer cells are resistant to TRAIL-mediated apoptosis.
Naturally occurring phenolic and polyphenolic compounds sensitize TRAIL-resistant cancer cells and augment the apoptotic activity of TRAIL. The ethanolic extract of Brazilian green propolis (EEP) is rich in phenolic components.
Our in vitro results indicate the potential targets in the TRAIL-induced apoptotic pathway for the cancer chemopreventive activity of Brazilian propolis.
We examined the cytotoxic and apoptotic effects of Brazilian EEP and its bioactive components in combination with TRAIL on LNCaP prostate cancer cells…
The inhibition of nuclear factor-κB (NF-κB) (p65) activation in cancer cells was confirmed by the ELISA-based TransAM NF-κB kit. The LNCaP cells were shown to be resistant to TRAIL-induced apoptosis. Our study demonstrates that EEP sensitizes TRAIL-resistant prostate cancer cells.
The main phenolic components detected in Brazilian green propolis are artepillin C, quercetin, kaempferol and p-coumaric acid. Brazilian propolis and its bioactive components markedly augmented TRAIL-mediated apoptosis and cytotoxicity in prostate cancer cells.
Brazilian EEP enhanced the expression of TRAIL-R2 and the activity of NF-κB in LNCaP cells. The co-treatment of prostate cancer cells with 100 ng/ml TRAIL and 50 µg/ml EEP increased the percentage of apoptotic cells to 65.8±1.2% and caused a significant disruption of ∆Ψm in LNCaP cells.
We show that Brazilian EEP helped cells overcome TRAIL resistance by engaging both intrinsic and extrinsic apoptotic pathways and regulating NF-κB activity.
The data demonstrate the important role of Brazilian green propolis and its bioactive compounds in prostate cancer chemoprevention through the enhancement of TRAIL-mediated apoptosis.
Propolis Component May Help Prevent Atherosclerosis
Caffeic Acid Phenethyl Ester Inhibits PDGF-Induced Proliferation of Vascular Smooth Muscle Cells via Activation of p38 MAPK, HIF-1α, and Heme Oxygenase-1
J Nat Prod, 2011 Jan 25
Hyperproliferation of vascular smooth muscle cells (VSMCs) is critically involved in the onset of atherosclerosis and restenosis. Although caffeic acid phenethyl ester (CAPE, 1), one of the main constituents of honeybee propolis, has been shown to exert a beneficial effect in models of vascular injury in vivo, detailed mechanistic investigations in vascular cells are scarce.
This study has examined the antiproliferative activity of 1 in platelet-derived growth factor (PDGF)-stimulated primary rat aortic VSMCs and aimed to shed light on underlying molecular mechanisms.
Compound 1 inhibited the proliferation of VSMCs upon exposure to PDGF in a dose-dependent manner by interfering with cell cycle progression from the G0/1- to the S-phase. Enhanced phosphorylation of p38 mitogen-activated protein kinase (MAPK) as well as stabilization of hypoxia-inducible factor (HIF)-1α and subsequent induction of heme oxygenase-1 (HO-1) could be identified as molecular events contributing to the observed growth arrest in PDGF-activated VSMCs upon exposure to 1.
Royal Jelly Could be Used to Treat Colitis
Effect of Royal Jelly on Experimental Colitis Induced by Acetic Acid and Alteration of Mast Cell Distribution in the Colon of Rats
Eur J Histochem, 2010 Oct 21;54(4):e35
This study investigated the effects of royal jelly (RJ) on acetic acid-induced colitis in rats.
Twenty adult female Wistar albino rats were divided into four treatment groups of 5 animals each, including a control group (Group I); Group II was treated orally with RJ (150 mg kg-1 body weight); Group III had acetic acid-induced colitis; and Group IV had acetic acid-induced colitis treated orally with RJ (150 mg kg-1 body weight) for 4 weeks. Colitis was induced by intracolonic instillation of 4% acetic acid; the control group received physiological saline (10 kg-1). Colon samples were obtained under deep anaesthesia from animals in all groups. Tissues were fixed in 10% formalin neutral buffer solution for 24 h and embedded in paraffin. Six-micrometre-thick sections were stained with Mallory's triple stain and toluidine blue in 1% aqueous solution at pH 1.0 for 5 min (for Mast Cells).
RJ was shown to protect the colonic mucosa against the injurious effect of acetic acid. Colitis (colonic damage) was confirmed histomorphometrically as significant increases in the number of mast cells (MC) and colonic erosions in rats with acetic acid-induced colitis.
The RJ treatment significantly decreased the number of MC and reduced the area of colonic erosion in the colon of RJ-treated rats compared with rats with untreated colitis.
The results suggest that oral treatment with RJ could be used to treat colitis.
Portuguese Bee Pollen Shows Antimicrobial Activity
Honeybee-Collected Pollen from Five Portuguese Natural Parks: Palynological Origin, Phenolic Content, Antioxidant Properties and Antimicrobial Activity
Food and Chemical Toxicology, Article in Press
The aim of this study was to determine the palynological origin, phenolic content, antioxidant and antimicrobial properties of pollen from five Portuguese Natural-Parks [Parque Nacional Peneda Gerês (PNPG); Parque Natural do Montesinho (PNM); Parque Natural do Alvão (PNA); Parque Natural da Serra da Estrela (PNSE) and Parque Natural do Douro Internacional (PNDI)].
Eight families were found in the mixture of bee pollen: Rosaceae, Cistaceae, Boraginaceae, Asteraceae, Fagaceae, Ericaeae, Myrtaceae and Fabaceae. The phenolic compounds content, determined by the Folin-Ciocalteu method, varied between 10.5 and 16.8 mg of gallic acid equivalents/g of extract (mg GAE/g) found in bee pollen from PNM and PNDI, respectively. The free radical scavenging measured showed the highest effective extract - PNM with EC50 2.16, followed by PND with 2.24 mg/mL.
In the β-carotene bleaching assay the same behaviour as in the DPPH method was verified. We also verified that the presence of pollen differentially affected the growth of bacteria Gram-positive, Gram-negative and yeasts under study, depending this on the microorganism and the pollen used.
This is an important study since, as far we know, it is the first time that Portuguese bee pollen from Natural Parks was studied, and their characterization can increase their economic value.
Polyphenols Contribute to Antioxidant Activity of Honey Melanoidins
Honey Melanoidins: Analysis of the Compositions of the High Molecular Weight Melanoidins Exhibiting Radical-Scavenging Activity
Food Chemistry, Article in Press
Size-exclusion chromatography (SEC) and activity-guided fractionation of honeys allowed the isolation of high molecular weight brown compounds, ranging in size from 66 to 235 kDa that exhibited peroxyl radical-scavenging activity. Their concentrations, antioxidant activity and degree of browning increased after heat-treatment of honeys, suggesting that they represent melanoidins.
Chemical analysis of melanoidins demonstrated the presence of proteins, polyphenols and oligosaccharides. Heat-treatment caused an increased incorporation of phenolics into high molecular weight melanoidins and drastically decreased the protein content in these fractions with a concomitant appearance of high molecular weight protein-polyphenol complexes of reduced solubility. LC-ESI-MS demonstrated the presence of oligosaccharide moieties, supporting the postulated origin of melanoidins.
The changes in the phenolic content of melanoidins from heated honeys were strongly correlated with their oxygen radical absorbance capacity (ORAC) values (R=0.75, p<0.0001), indicating that polyphenols contribute to the antioxidant activity of melanoidins.
In summary, honey melanoidins are multi-component polymers consisting of protein-polyphenol-oligosaccharide complexes. A direct interaction between polyphenols and melanoidins resulted in a loss or gain of function for melanoidin antioxidant activity.
Evidence for a spontaneous formation of melanoidins in unheated raw honeys. Demonstration that the melanoidin structure is composed of the protein-polyphenol-polycarbohydrate complexes. Formation of polyphenol – containing melanoidin complexes in honey were significantly correlated with a loss or gain of antioxidant properties of melanoidins.
Brazilian Green Propolis Component Reduces DNA Damage
Antigenotoxicity of Artepillin C in vivo Evaluated by the Micronucleus and Comet Assays
J Appl Toxicol, 2011 Jan 24
Artepillin C (3,5-diprenyl-p-coumaric acid), a major compound found in Brazilian green propolis and Baccharis dracunculifolia, shows anti-inflammatory, antibacterial, antiviral, antioxidant and antitumoral activities, among others.
The aim of this study was to evaluate the genotoxic potential of artepillin C and its ability to prevent the chemically induced chromosome breakage or loss and the primary DNA damage using the micronucleus and comet assays in male Swiss mice, respectively.
The animals were treated by gavage with different doses of artepillin C (0.4, 0.8 and 1.6 mg kg(-1) b.w.). For the antigenotoxicity assays, the different doses of artepillin C were administered simultaneously to doxorubicin (DXR; micronucleus test; 15 mg kg(-1) b.w.) and to methyl methanesulfonate (MMS; comet assay; 40 mg kg(-1) b.w.).
The results showed that artepillin C itself was not genotoxic in the mouse micronucleus and comet assays. In the animals treated with artepillin C and DXR, the number of micronucleated reticulocytes was significantly lower in comparison with the animals treated only with DXR.
Regarding antigenotoxicity, artepillin C at the tested doses significantly reduced the extent of DNA damage in liver cells induced by MMS.
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text:
Prospects and Future Plans
Apart from our commitment to the development of our principle business, we will actively make progress to generate growth and strive for potential and new business opportunities. The Group plans to further its growth in existing business by strengthening its marketing capabilities and expanding its product portfolio through enhancing software development, with a view to further enlarging its market share in Hong Kong and Macau and becoming one of the active biometrics identification solutions providers in the PRC. As such, the Group plans to utilise the net proceeds from the initial public offering of the Share by way of share offer pursuant to the Prospectus on (i) expanding the business in Southern China; (ii) improving its information technology system; and (iii) setting up a new and separate software development center in the PRC to further enhance and develop the Group's software.
Expanding the business in Southern China
Improving its information technology system
Setting up a new and separate software development center in the PRC to further enhance and develop the Group's software
Address: Unit A, 6/F, TLP 132, Nos 132-134 Tai Lin Pai Road, Kwai Chung, New Territories, Hong Kong
Tel: (852)2991 1112
Email: ir@primeintelligence.com.hk
© 2020 Prime Intelligence Solutions Group Limited. All rights reserved.
Website Created by Rovertech


Little Bessie, the bright and interesting little daughter of Mr. and Mrs. John Asa Dobbs, died at their home Sunday night, of pneumonia. She was taken ill suddenly while at school at West End Institute, on Friday last. She was the only child of her parents who have lost four others within the last few years.
The funeral took place from the West End Institute at 10:30 Monday morning, the school marching in a body from the home to the school. Rev. W. H. Patterson officiated.


Internships at Susquehanna Style and Innovative Designs & Publishing provide college students the opportunity to gain valuable experience and exposure to the exciting world of publishing. We provide students the chance to learn skills in a variety of areas including editorial, marketing/public relations, accounting, graphic design, photography and digital marketing.
Interns can receive college credit and positions are offered at both parttime (approximately 15 hours a week) and full-time (approximately 30 hours a week) with flexible hours. Though unpaid, internships are a great way to help students explore their career options and gain experience outside the classroom.


Elena goes to a very weird school where the attendance criteria is for each day of the semester. She is very lazy and thinks of ways to spend minimum time at the school. There are a total of N lectures tomorrow out of which she has to attend at least 75% of the lectures. Tell her at which time she should go to attend the lectures and the time that she should come back so that she spends least amount of time at school. Of course you don't want her to fail due to "low attendance".
If there are multiple answers then print the one in which she goes to school late.
First line contains an integer N, the number of lectures. Second line contains N space separated integers representing the time of commencement of ith lecture.
Print two space separated integers, first being the time she goes to school and second being the time she returns from the school.
Note: Each lecture is of 1 hour of duration and no two lectures start at same time.


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Is there really a point to spending the money on two hearing aids when your hearing loss only affects one ear? Let's look at why you might consider getting two hearing aids and when one really is enough.
The three primary reasons to opt for one hearing aid is you have single-sided hearing loss, you're completely and irreversibly deaf in one ear or you have age-induced cognitive delays.
If you have hearing loss in only one ear, there is no need to have a hearing aid in your other. Likewise, if you are permanently deaf in one ear, there is no point in purchasing a second hearing aid. Neither of these situations would improve with the addition of a second hearing aid.


Chancellor Angela Merkel described the internet as "virgin territory" during a press conference with President Obama on Wednesday, prompting Twitter to explode with mockery about her recent discovery of a brave new online world.
"The internet is virgin territory (Neuland) for us all," Merkel declared on Wednesday. But if she had meant to make a meaningful comment on the borderless, Wild West nature of the internet, it was lost on German internet users - who took to Twitter to poke fun.
Within minutes of her comment, the social network was buzzing with Tweets wondering what planet the Chancellor had been living on for the last twenty years.
Then, using the hashtag #neuland, a trickle of scornful memes began appearing which soon swelled into a viral flood as word got out across the Twittersphere.
By Wednesday evening #neuland was trending in Germany higher than #obamainberlin - and the Merkel memes kept coming.
So, just in case you missed them, The Local has gathered some #neuland highlights into one place – for even non-Twitter users (and Neuland newbies) to enjoy.
Can Merkel hold on as chancellor after stepping down as CDU chief?


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Very often, for our programs, we need a system to set parameters, usually of a numerical type. A 4×4 keyboard requires some space and then we also need a display. Here is the idea of using a touchscreen display to do both. I have then written the GetNum function that allows you to print a prompt message and to type an integer number. To test this function I wrote a simple analog data logger program that required two parameters, the first is the sampling period and the second the number of samples. In this example the number of channels to be scanned is set to three, but the program can be modified to request a third parameter with the number of channels.
See the full post on ArduPicLab blog.
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