Visit CtyImmune.blog for our Latest Science and Insights.
We break through tumor defenses to enable cancer cures.
A tumor is a fortress whose defenses can block chemotherapies from reaching the cancer cells growing inside. To expose cancer cells to cancer cell killers, the nutritional support structures and protective barriers of tumors must first be destroyed.
CytImmune's nanotherapy platform, Aurimune, is a tumor-targeted Trojan horse. It is engineered to travel safely and stealthily through the body and enter tumors through their most vulnerable points – the leaky blood vessels that make up the nutritional support structures. Aurimune selectively binds TNF receptors on blood vessel cells at the site of disease. Once bound, Aurimune unleashes a therapeutic payload that destroys the tumor's nutritional support structures and protective barriers.
This "opens the gate" for cancer cell killers to penetrate the tumor and eradicate disease.
Tumors have blood vessels that are abnormally porous. These leaky blood vessels form the nutritional support structures that enable tumors to absorb fluids to feed cancer cell growth with no efficient route for exit, thereby creating a protective pressure gradient inside the tumor (like inflating a balloon), but outside the blood stream itself. This protective pressure gradient effectively blocks anti-cancer agents from reaching their target – the cancer cells inside the tumor.
It's widely known and accepted that a naturally occurring molecule, tumor necrosis factor (TNF), which is part of our own immune system, is capable of destroying the nutritional support structures (leaky vasculature) of tumors, and in doing so, removes the protective pressure barrier of tumors.
As demonstrated in numerous clinical settings, local administration of TNF at the site of disease normalizes blood flow through tumors, exposing cancer cells to cancer cell killers as all pressure resistance is gone. But TNF's inherent toxicity has prevented it from being used systemically to treat cancer patients -- until now.
Aurimune safely delivers TNF systemically to tumors at clinically effective levels with no dose limiting toxicity.
Aliquam pulvinar neque tristique enim rutrum, ac blandit orci dignissim aliquam sed consectetur massa, et tempor tellus quisque vulputate, orci id adipiscing tincidunt, massa tortor luctus lectus, a sodales magna est sit amet urna.
A water shield surrounds the Aurimune nanoparticle and hides its toxic payload. This water shield is created through a peg-thiol technology and prevents toxics substances – like TNF – from reaching and damaging healthy blood vessels and tissues. Collateral damage of this type is typically the underlying cause of dose limiting toxicity for most chemotherapy. The Aurimune water shield also allows the nanotechnology to evade immune detection, allowing the nanomedicine to pass through the circulatory system and access tumors through their unique biological support structures (leaky blood vessels).
Aurimune exits the circulation only at the site of disease as it is precisely sized to pass through the abnormally large gaps found in tumor blood vessels.
Upon reaching its pre-determined target, Aurimune selectively binds to specific TNF receptors of blood vessel cells at tumor sites and then exerts its biologic action, which destroys the nutritional support structures and protective pressure barriers of tumors. This "opens the gate" for cancer cell killers to freely penetrate the tumor and eradicate disease.
When the tumor support structure (blood vessels) is destroyed, the positive pressure gradient that protects cancer cells inside the tumor is removed and cancer cells are then exposed to cancer cell killers (follow-on therapies) as blood flow through the tumor is normalized.
CYT-6091 is the first in a family of neo-adjuvant, Aurimune-based nanotherapies designed to amplifiy the effectiveness of either follow-on administration of chemotherapy or anti-cancer agents bound to nanoparticle itself.
Cytimmune has successfully attached both biological and small chemical anti-cancer agents to the Aurimune delivery platform and has proven that cancer cell-killing therapies can be delivered along with TNF to open up tumors and destroy the cancer cells inside.
CytImmune created Aurimune to make a quantum leap forward in the technology available to safely and effectively deliver a range of anti-cancer therapies into tumors.
The center of the Aurimune platform is a precisely sized gold nanoparticle. Sizing is optimized to leverage the inherent leakiness of tumor blood vessels. Gold has low toxicity and regulators understand its safety profile since it has been used therapeutically in humans for decades.
PEG is a water-absorbing molecule that covers the gold particle like tiny hairs and is key to the stealthy nature of the Aurimune platform. PEG attracts and holds a protective water shield around the nanotherapy as it passes through the body. This creates the "water shield" that surrounds the nanomedicine.
TNF breaks down the blood vessel architecture inside tumors. This makes the cancer cells inside the tumor vulnerable to anti-cancer agents.
CytImmune developed patented linker technology to attach small molecule, anti-cancer agents directly to the Aurimune nanomedicine. These linkers are unique and can be adjusted to work with a variety of agents targeting multiple tumor types.
Other biological or chemical anti-cancer agents can be added to the core Aurimmune nanomedicine. They can be precisely delivered to kill growing cancer cells inside the tumor.
A first generation Aurimune platform nanotherapy, CYT-6091, carries TNF into tumors to disrupt their blood vessels and enable follow-on chemotherapy to penetrate the tumor and kill the cancer cells inside. In a successful Phase I clinical trial, CYT-6091 safely delivered what would have been a toxic but highly effective dose of the anti-cancer agent TNF to patients; dose levels were three times the previous maximum tolerated dose. Tissue samples, taken 24 hours after CYT-6091 administration, showed that the nanomedicine had concentrated inside tumor tissues, not inside surrounding healthy tissue.
A Phase II clinical trial will treat pancreatic cancer patients in combination with standard of care second line therapy. Additional details related to the Phase II trial will be announced.
A second generation Aurimune platform nanomedicine, CYT-21000, carries Taxol (paclitaxel) in addition to TNF. Aurimune is currently the only nanotechnology that has been able to simultaneously deliver a biologic, TNF, and a small molecule therapeutic, Taxol, carried by the same nanoparticle.
CytImmune is currently working with AstraZeneca's Oncology Innovative Medicines Unit to examine the viability of delivering one or more AstraZeneca anti-cancer therapies into solid tumors using the Aurimune nanomedicine platform.
The Aurimune nanomedicine platform offers the potential to enable and/or expand the clinical benefit of a variety of toxic anti-cancer therapies -- either as monotherapies or in combination with existing standards of care. Aurimune functions are independent of tumor-specific biochemistry; therefore it does not depend on the type of cancer treated.
However, since cancer is not a single disease, CytImmune has developed a pipeline of Aurimune-based products to attack cancers through different biologic pathways.
- A successful track record working with other institutions to integrate existing anti-cancer agents onto the Aurimune nanomedicine, rescuing molecules whose systemic toxicity has stifled clinical development.
CytImmune is open to investigating potential partnerships. For more information, contact Mitchell Marder at (301) 825-3041.
Founded in 1988, CytImmune has transitioned from a successful diagnostics company into a clinical stage nanomedicine company with a core focus on the discovery, development and commercialization of multifunctional, tumor-targeted therapies.
CytImmune is a global leader in the field of nanomedicine with the successful completion of a Phase I clinical trial of CYT-6091 — the first in a series of products based on the CytImmune's Aurimune nanomedicine platform. The company has more than 60 issued and pending patents for its colloidal gold nanotechnology in the United States, European Union, Japan and Canada.
Executive Chairman of ExoCyte Therapeutics Pte. Ltd.
Group General Manager, Itanis International, Inc.
Prof. Kouji Matsushima, M.D., Ph.D.
COPYRIGHT © 2017 CYTIMMUNE SCIENCES, INC.


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text:
Q: How to determine value changes according to another columns in Oracle Below table includes non-unique id, money value and dates/times.
id_1   value_1     value_time       id_version      Version_time
138    250         09-SEP-14        595             02-SEP-14
140    250         15-SEP-14        695             01-AUG-14
140    300         30-DEC-14        720             05-NOV-14
233    250         01-JUN-15        800             16-MAY-15

As you can see id_1, id_version and time columns can change in table but value_1 may stay the same.
I know that if id_1 is same in rows, value_1 can only change according to id_version. But there are too many id_version in the table. And I know that it changes according to id_version, but i don't know the exact change time of it.
So firstly I have to decide, which id_version and id_version time cause the value change group by id_1.
But again id_1 is not uniqe, and id may change but value stays the same :)
editor: From OP's comment - Begin
Here is the desired result example i want to get the first and second row not the third and fourth row.
| 140 | 250 | 15-SEP-14 | 695 | 01-AUG-14 |
| 140 | 300 | 31-DEC-14 | 725 | 07-NOV-14 |
| 140 | 300 | 05-JAN-14 | 740 | 30-NOV-14 |
| 140 | 300 | 30-DEC-14 | 720 | 05-NOV-14 |

editor: From OP's comment - End
Thanks in advance really need help in this situation.

A: Based on the input given so far (and processing just the data in the linked to picture - rather than the one in the current example data), the following should help to get you started:
SELECT
  TMin.id_1
  , TMin.value_1
  , TO_CHAR(TAll.value_time, 'DD-MON-RR') value_time
  , TMin.id_version
  , TO_CHAR(TMin.version_time, 'DD-MON-RR') version_time
FROM
  (SELECT
    id_1
    , value_1
    , MIN(id_version) id_version
    , MIN(version_time) version_time
  FROM T
  GROUP BY id_1, value_1
  ORDER BY id_1, value_1
  ) TMin
JOIN T TAll
  ON TMin.id_1 = TAll.id_1
  AND TMin.value_1 = TAll.value_1
  AND TMin.id_version = TAll.id_version
  AND TMin.version_time = TAll.version_time
ORDER BY TMin.id_1, TMin.value_1
;

See it in action: SQL Fiddle.
Please comment, if and as this requires adjustment / further detail.

redpajama_set_name: RedPajamaStackExchange


The 2016 awards for the European Satellite Navigation Competition and Copernicus Masters will be announced and celebrated at a gala ceremony in Madrid, Spain on October 25. The event recognizes the winning applications using the Galileo GNSS, EGNOS augmentation system and Copernicus earth observation system.
development, publicity, and marketing support..
On October 26, the third Satellite Masters Conference will feature speakers from Europe's GNSS government and industry leadership and a program on new applications for Galileo, Copernicus and EGNOS.
The event is co-sponsored by Anwendungszentrum GmbH Oberpfaffenhofen (AZO) and the Fundacion para el Conocimiento madri+d and the Comunidad de Madrid.


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text:
Riz Ahmed and Mohsin Hamid – cultural break-up, make-up and mash-up – from the margins to the mainstream… (London Literature Festival 2018)
A manifesto for change…??
STRETCHING culture, creating gaps and altering some mainstream and loaded narratives is all part of an alternative vision Riz Ahmed put forward at his recent London Literature Festival talk.
In a wide-ranging discussion mostly on culture, Ahmed powerfully distilled some of the most pressing cultural issues of the day – saying that even from his shortened name – Riz, from Rizwan/Rizwaan – much could be read – and misread.
The actor, writer, musician (and activist), made a rare UK appearance at the festival's end on Sunday (October 28), alongside novelist Mohsin Hamid and moderator Kieran Yates to discuss Migration and Magic.
(L-R); Riz Ahmed, Kieran Yates, and Mohsin Hamid
Yates is a journalist and cultural commentator and also a co-contributor to Nikesh Shukla's hugely successful ground-breaking and award-winning collection of essays, 'The Good Immigrant' (edited by Shukla and a crowd-funded initiative).
Ahmed is another contributor and is the showrunner for the forthcoming (2019) 'Englistan', a nine-part BBC2 drama series which will chart the history of a British family and its three generations, who are of Muslim heritage.
Expanding on previous thoughts ("a citizen of nowhere but with a visa to go everywhere") in his BBC The Big Asian Summer interview with Nikki Bedi, Ahmed suggested that the most interesting parts of culture are at the margins, with people trying to create a space and narratives that include them.
"It's like the Zadie Smith saying where she says she wants to insert and see herself in terms like British," asserted Ahmed at the talk.
Smith's novel 'White Teeth' (2000) is often celebrated as the voice of a minority culture writing itself into the fabric of British (and English) narratives – making the nation's minority groups visible and relevant.
Ahmed suggested this is the space he likes to work in himself, inserting, interjecting (even) and stretching culture and opinion and thought, to the point where minority communities are – no longer marginalised or made invisible or as is often the case within a larger narrative – disrespected and abused.
He told the audience that his parents had given him the name Rizwa(a)n but he had shortened it to 'Riz'.
"We are a nation of one-syllable names – Dave, John, and now Raj, Dev…" he said, half tongue-in-cheek.
He felt totally at home with the idea of being Riz, but every time he stepped into the cab of an Arabic-speaking (or influenced) driver, he became 'Rizwaan' – he joked.
Riz Ahmed and Kieran Yates
This was his idea of changing a narrative, slipping yourself into it and stretching the idea of Britishness or Englishness to be more inclusive than it might be at present.
There is now a Riz and Dev to add all the Daves and Johns, all of whom might be English and British.
"I don't like the term political," Ahmed said, which some use to describe his general stance (and activism).
The point being, that it is often, though not always, a label used to categorise and neutralise what he is saying.
Two of his current films illustrate how far he has come and how some have listened and responded positively to his arguments for Representation – not Diversity (which he likens to a burger topping, not unappealing in itself, but slight and superficial).
In both 'The Sisters Brothers' and 'Venom' he plays non-ethnic characters and brings his own admirable sensibility to them.
"We want representation," he mused at the talk. At the Toronto International Film Festival, acv was able to ask him about his role in 'The Sisters Brothers' – which also featured in last month's London Film Festival.
Colour-blind and open casting are important, he argued in letting people see talent and letting the character do the work.
Humorously, he posited that it does not work the other way around – you do not need a white actor to play Othello.
Hamid, whose last novel, 'Exit West' – was declared by President Barack Obama as one of the best he had read in 2017 – sees a couple migrate from one global city to another in search of a settled life, told the audience about his decision to move back to Lahore, Pakistan.
Show of hands – who are the brown people in the audience?
He had first left the country of his birth to study in the US and has worked in both in the US and London. His two later novels 'How to get filthy rich rich in rising Asia' (2013) and 'Exit West' take place in mostly unnamed cities – unlike his first novel, 'Moth Smoke' (200), which is very much centred around Lahore.
His decision to return was made because of family – his parents have an active role in his children's lives and while it was not perfect, it offered him the best sense of 'home', he had experienced, he said.
The talk started humorously with a 'bet' (between Ahmed and Hamid, as to what the ethnic make-up of the audience would be). Ahmed claimed he had won and casually estimated that the audience was about 75 per cent non-white, through a show of hands. To acv, it looked more like 60-65 per cent.
Towards the end in an open Q&A session with the audience, there was aslo a short discussion about ethnic minorities and mental health prompted by a question.
Ahmed said he was proud of his psychiatrist brother who has done work in the area. He affirmed his support for talking more openly about mental health issues as a community and looking at how much racism might play a part in contributing to people's breakdowns and mental health issues.
Prior to Sunday, Sir Salman Rushdie and hip-hop poet Akala were among those that could be heard at the London Literature Festival (October 18-28 2018).
(Sailesh Ram)
All pictures: ©India Roper-Evans (Southbank Centre Media)
Some talks are already available as podcasts https://soundcloud.com/southbankcentre_book_podcast
And a video of this talk is set to be published.
*There are more Literature talks at the Southbank Centre, including Michelle Obama, launching her memoir, 'Becoming' exclusively in the UK on December 3. For tickets & details, please see here http://asianculturevulture.com/portfolios/riz-ahmed-and-mohsin-hamid-at-london-literature-festival/
Mohsin AhmedRiz Ahmed
AUTHOR KAMILA SHAMSIE AT FEST
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May 28 2014 A new novel charts the origins of the Naxalite (Maoist) movement in West Bengal, India and poses…read more →
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← Tasty or not? Indian films from the London Film Festival
AUNTIJIS MAD FOR SHAH RUKH – NEW PLAY →

redpajama_set_name: RedPajamaCommonCrawl


These days, such a question carries a very fine line and is not as obvious as you may think. Years ago, if you were under the age of eighteen and were arrested for any criminal case(s), you were treated and charged as a juvenile since the fact is you were a juvenile. Wow, have times changed.
Today, children as young as fifteen are being arrested as juveniles but charged (direct filed) as adults. Certainly, some direct files can be substantiated by the heinous nature of some violent/sexual offenses. However, many cases that are not at all serious are being prosecuted as adult cases because of a backlog of cases in the juvenile system.
However, I recently represented a juvenile client who had a burglary case from December, 2011 and recently picked up a felony drug possession charge. He was arrested with two other juveniles. He was held in custody until I got on the case and within 48 hours I had a Motion to Modify Pre-Trial Release heard by the judge which resulted in him being released on home detention. The State wanted to direct file my client solely because he was seventeen (17) and any period of the probationary sentence would have gone passed his 18th birthday. Huh? Really? The law says we should charge juveniles as juveniles with few exceptions such as the ones mentioned above. None of which is because he will be 18 when his juvenile sentence is set to end.
I was successful in negotiating a resolution that allowed the Burglary charge and the Felony Drug Possession charge to remain in juvenile court. Doing so is extremely important since the nature of the charge in adult court is one that can never be sealed or expunged, thus affecting the client's ability to apply for college or any future employment.
The unfortunate reality is that the co-defendants who were not represented by a private attorney met a much different fate. They were direct filed to adult court where they are now facing up to twenty (20) years in adult state prison, all at the ripe young, juvenile age of 17.
The mindset used to be that Juvenile Court's sole purpose is to rehabilitate and adult court is to punish. Experience tells me that such is only half true with the current trend of rushing to treat juveniles as adults on non-serious felonies.
Many of these "kids" do not stand a fighting chance in their pursuit of their hopes and dreams if they are treated as adults before they turn 18.


Samsung - the world's largest smartphone maker - fights to maintain its market share. The Samsung Galaxy M is part of the solution and adds a couple of affordable wallet devices.
Explicitly designed to attract young people - the millennium - in India, the Galaxy M comes in two shapes, the M20 and M10 being slightly lower.
Manish Tiwary, head of the department management department at Amazon India in India, will offer the Samsung Galaxy M series: "The first Samsung Galaxy M series in India will resonate with the millennium warriors who are looking for powerful devices."
The Samsung Galaxy M Series debuts with a new style of display for Samsung with Infinity-V, in the form of a tear on the front, instead of the alleged Infinity-O drill for the Samsung Galaxy S10.
The main features of the Galaxy M20 are a 6.3-inch Full HD display with a resolution of 2340 x 1080 pixels, an Exynos 7904 platform and a fingerprint scanner. There will be 3 / 32GB or 4 / 64GB variants, with support for microSD expansion.
The most exciting may be a massive 5000 mAh battery with a 15 W charger in the box and a USB key with the C button on the quick charging phone.
The Samsung Galaxy M10 falls to a 6.2-inch screen with HD + resolution (probably 1550 x 720 pixels), Exynos 7870 and no fingerprint scanners. It will be available in 2 / 16GB and 3 / 32GB versions. It has a smaller 3400mAh battery.
Both phones have a twin-dimensional camera with a 13-megapixel main camera and a 5-megapixel wide angle lens. The M20 is an 8-megapixel front camera and a 5-megapixel resolution on the M10.
Both phones work under the Samsung Experience UX 9.5 and will be available from February 5, 2019, in India, Samsung, which wants to compete with Xiaomi, a subscriber of Redmi, to sell volumes of affordable devices.


So guess that means it is not in the initial plans.
Q: Your probably getting all "asked"-out by now but I got another one. Any chance we'll see any of Gambit's King of Thieves shenanigans get addressed? I guess that makes Rogue the... Queen of Thieves, doesn't it?
I don't think that we will see Guilds.
I send KT on Tumblr 2 questuons. She answered about Deadpool but ignored question about Jean-Luc and Tante.
I don't see Gambit to be married and not at least to share news with them.
Can't take away from Rogue and Deadpool panel time. Sorry the hate just comes so naturally.
Nope, but I can hope. I think I'm more partial to his Guild matter than most.
Wild card and Queen of Heats.
And yet, still no Mike Choi variant. Talk about a tragedy.
I love this variant cover alot.
Cheese and rice, I hate that title graphic!
Some variants should be completely blank. Like if you're going to the trouble of getting a variant, you know what book it is, lol. I like it, the noses are a little weird, hairs not bugging me though.
No Choi variant is a shame,no Clay Mann variant is travesty!
I think Mann is with DC, has an exclusive or something but I could be wrong.
As for the covers, too many ... it worries me about incentive programs and the availability if one is wanting a cover. Having been aggressive in the past to get variants, I hope those looking have good luck.
It is really unfortunate we won't be getting a Clay Mann variant.. but it's gutting knowing he can't ever work on this book unless something were to happen with DC.
I am glad for Clay. He is working on best selling book right now and became artist super start. I am sure DC treats him and their artist better.
Jim Cheung left for DC too.
Carmine Di Giandomenico also left after X-Factor. I think he is the only one who can draw bi monthly books.
Now when Immonen at retirement Marvel should really pay more and keep Marquez, McNiven and Larraz.
Not a lot of A lists are left.
Carmine Di Giandomenico .... wow ... loved his art, the fact he was fast and consistent is amazing. I would love for him to draw Gambit again. Liked his take, just like I like Mann's take on G. Marvel has lost some talent over the years.


text:
First Impressions Devilian
November 2, 2012 17:43 0
TBD Overall Score
Visceral combat, beautiful graphics, interesting storyline/narratives
Nothing stand out original, very classic questing mechanics
We were invited to the closed beta testing of Devilian recently, the free to play action RPG from Trion Worlds. Originally released in South Korea, the game will soon be hitting western shores giving EU and NA players the chance to check out the game. We stepped into the world with mixed expectations and hopes, another South Korean action RPG was not at the top of the list of games we felt we needed to see, but any doubt we had were quickly silenced.
To start the game looks great, roaming around the opening levels and beyond some of the views and camera angles are extremely clever giving a real sense of height, whether crossing a bone bridge high above a cavern, fighting alongside a jagged cliff, or roaming around huge open floating cities. Whilst it may be a tactic the developers have used quite a lot, having every battle happen high up somewhere, the level design and graphical detail makes a really immersive environment that straight away had us thinking that the game was nearly on par with the likes of Diablo 3 in terms of quality.
Second to quieten our doubts were the translations/quest dialogue, any Asian import is typically littered throughout with spelling mistakes and horrible grammar, but there weren't any issues in this regard from what we had noticed and that in itself was a breath of fresh air. Dialogue and story was refreshingly interesting, well written and meaningful; getting to the point yet still delivering information to us and doing so in a way that builds up the NPC characters.
For our own adventure we decided to choose the Evoker class; a magic caster that summons up the elements, with the other three classes being a Cannoneer who uses huge guns, a Shadowhunter that used a ranged chain whip and the Berserker who uses two blades in melee. The classes are restricted to their set characters/genders, the Evoker and Cannoneer being female and the Berserker and Shadowhunter being male; it's not the worst thing in the world and there was a slight ability to customize hair and skin colour, but the game is built for fun and the story journey as opposed to players roleplaying their own characters and making a unique identity.
Combat is particularly well done with the movement being handles with classic WASD or using left mouse click, and combat hotkey abilities being bound to the number keys; the mouse is used to determine the direction of your attack or spell. As spell casters who could perform their abilities at range this also meant that as well as simply hitting the 1 key to send out a ranged attack towards the cursor, we could also pinpoint our area attacks, such as our Lightning Strike, to hit the area that our mouse cursor was hovering over. Aiming, moving, using the space bar to short range teleport to dodge enemy attacks, it was relatively simple in theory but proved to be a bit of a macro workout for the fingers when facing a lot of opponents. The fast paced nature was extremely fun and, at least with the Evoker, the effects from our abilities were extremely fun with throwing our fireballs and arcs of lightning lighting up the place, erupting out enemies into a fountain of blood and bone.
As we were given a Beta account this game with a variety of boosts including some inventory expansion tickets (which were much needed), extra character slots (2 as default), a battle polar bear mount, a Corgi companion (yes, the little dog) who would give us boosts when he was summoned. It did also give each player 50 Announcement Horns, where you could make an announcement seemingly to the entire game so it appeared in every chat window… useful for testers but a bit annoying for recording a video as you couldn't hide the windows or turn the announcements off (from what we could tell anyway).
The early game content we managed to explore was fun, reaching around level 13 we finally got the chance to explore one of the main features of the game: our Devilian form, albeit it was short lived and only fighting in a training room. Here we were able to build up a "Devilian Awaken" gauge by attacking enemies that, once filled, we could switch into a second Devilian form given that our character was half-devil. As a Devilian we had access to new and improved abilities, still similar to our standard class ones, but supercharged and with added effects to obliterate enemies and, in doing so, kept our gauge filled so that we stay in the form for longer. The PVE was generally pretty fun, though perhaps a little repetitive sometimes given the very similar nature of the quests to go and kill a certain amount of a specific monster. PVP we unfortunately didn't get to try, no matter how long we queued, though players will get the chance to fight in 3v3 battles, 20v20 and even Guild vs Guild wars, which we think will be great fun.
Overall the game is interesting for what it offers, but it doesn't feel like anything incredibly unique; in a sea of free to play action RPGs that are all extremely similar we'll concede the Devilian does stand head and shoulders above most in terms of its final quality. Unfortunately whilst it smashes our expectations, which over the years have become pretty low with Asian import RPGs, by smashing our expectations it only brings it up to a level where we'd expect a AAA RPG to be in its basic form for the core aspects of the game. Diablo, Marvel Heroes 2015, Torchlight, Path of Exile, these games all offer so much more than Devilian does, though we'll happily give the game the benefit of the doubt when it comes to PVP as we can imagine the fluid combat will make it extremely fun.
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text:
Q: Branching statement issue (TikZ) I am using a branching statement in a tikzpicture as presented in the TikZ & PGF Manual (p. 634). Here is a MWE :
\documentclass{article}

\usepackage[letterpaper,textwidth=8.5in,textheight=11in]{geometry}
\usepackage{tikz}
\usetikzlibrary{math}

\begin{document}
\pagestyle{empty}
\begin{figure}
\centering
\begin{tikzpicture}

\tikzmath{
\a = 2;
if \a <= 5 then {
\draw (0,0) rectangle (\a,\a);
} else {
\draw (0,0) parabola (\a,\a);
};
}

\end{tikzpicture}
\end{figure}
\end{document}

Nevertheless, it does not work... What am I doing wrong?
I get the following error :

A: I think you want something like this, though I'm not terribly familiar with this library:
\documentclass[tikz,border=10pt]{standalone}
\usetikzlibrary{math}

\begin{document}
  \begin{tikzpicture}
    \tikzmath{
      \a = 2;
      if \a <= 5 then { let \b = rectangle; } else { let \b = parabola; };
    }
    \draw (0,0) \b (\a,\a);
  \end{tikzpicture}
\end{document}

Alternatively, you can do the drawing within the parser if you protect it with {...};.
\documentclass[tikz,border=10pt]{standalone}
\usetikzlibrary{math}

\begin{document}
  \begin{tikzpicture}
    \tikzmath{
      \a = 6;
      if \a <= 5 then { let \b = rectangle; } else { let \b = parabola; };
      { \draw (0,0) \b (\a,\a); };
    }
  \end{tikzpicture}
\end{document}

Or you can use similar protection to do the drawing within the conditional:
\documentclass[tikz,border=10pt]{standalone}
\usetikzlibrary{math}

\begin{document}
  \begin{tikzpicture}
    \tikzmath{
      \a = 1;
      if \a <= 5 then { {\draw (0,0) rectangle (\a,\a);}; } else { {\draw (0,0) parabola (\a,\a);}; };
    }
  \end{tikzpicture}
\end{document}

A: As cfr points out the intended way of executing code outside tikzmath parser is to place it inside braces (followed by a semicolon). No braces are required around the condition though:
\tikzmath{
  \a = 2;
  if \a <= 5 then {
    { \draw (0,0) rectangle (\a,\a); };
  }   else {
    { \draw (0,0) parabola (\a,\a); };
  };
}


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text:
Q: Create Unit and Instrumentation test for Android project with dynamic features I have a project where I have main :app package. Besides that, the app contains of two dynamic features inside the same package, :features:A and :features:B.
The issue here is that I can't run Unit and Instrumentation tests (Espresso, UI Automator) because of the following error(s):
"AAPT: error: resource string/app_name (aka com.app.A.test:string/app_name) not found."

When I run tests(UI tests in this case) App compiles and works without any issues.
I figured out that error occurs on manifest merging, as it can be seen from complete error:
/Users/user/company/app/features/A/build/intermediates/tmp/manifest/androidTest/app/debug/manifestMerger7870721738992192959.xml:7:5-9:19: AAPT: error: resource string/app_name (aka com.app.A.test:string/app_name) not found.

A: A library (A or B in the logs above) is requiring some value that is found in the merged manifest from the test variant. To fix it, you need to add the test dependency in the Dynamic Feature build.gradle:
dependencies {
    implementation project(":app")
    androidTestImplementation project(":app")
}


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text: Q: Why my activity restarts even I set android:configChanges="orientation|screenSize" in manifest file I have 2 activities: MainActivity and PdfViewActivity. I set both of them to android:configChanges="orientation|screenSize" in the manifest file. When I rotate my device, MainActivity doesn't restart while PdfActivity does even when I set configChanges in the manifest. Why?


text:
When a childless couple of an ex-con and his wife, an ex-cop decide to help themselves to one of another family's quintuplets, their lives get more complicated than they anticipated.
Nicolas Cage, Holly Hunter
Locked video
THEATRICAL TRAILER
Critics Consensus: A terrifically original, eccentric screwball comedy, Raising Arizona may not be the Coens' most disciplined movie, but it's one of their most purely entertaining.
Saporta Report (Atlanta)
Eleanor Ringel Cater
Yes, the Coens are techno-brat showoffs, but when the show is this good, who cares?
The Film Yap
Nick Rogers
In their first masterpiece, the Coens first delight with sheer kinetics, then dazzle with colorful...
Cathy Burke
A non-stop chase movie filled with so much good humor it's like an all-expense paid trip to anothe...
Raising Arizona is no big deal, but it has a rambunctious charm.
CinePassion
Fernando F. Croce
The immense joy of this is in the realization that, for all their precision, Joel and Ethan Coen a...
To their old fascination with Sunbelt pathology, to their side-winding Steadicam and pristine comm...
Sharp, inventive and hilarious, with a marvellous cast of Coen regulars.
Pat Graham
The cartoon vision of southwestern tackiness doesn't cut very deep, but the mise-en-scene is packe...
An entertaining, energetic, and stylish comedy about a simple but loving couple who long to be par...
Variety Staff
While film is filled with many splendid touches and plenty of yocks, it often doesn't hold togethe...
Hysterically twisted tale has profanity, violence.
Parents need to know that Raising Arizona is a classic 1987 Coen brothers film in which Nicholas Cage and Holly Hunt steal an infant from parents who recently gave birth to quintuplets after they learn they're unable to have children of their own. The main characters are kidnappers and convicts. A kidnapped baby is taken into perilous situations throughout, such as car chases, bank robberies, gunfights, and the like. One character is a bounty hunter of sorts who, in a dream sequence, destroys everything in his path, including bunny rabbits. A character blows up from a hand grenade. While the violence is often exaggerated for comedic or dramatic effect, there is an extended chase sequence in which gun and rifle fire is nonstop. Characters are shown bloodied and bruised in these fights. There is some profanity in nearly every scene -- including one use of "f--k" and variations on "s--t." A teen convenience store clerk looks at a pornographic magazine. There is some sex talk, often in the context of conceiving a baby.
Release Date:March 11, 1987
Seven Psychopaths
The Cleanse
Tomcats
Money for Nothing
Better Living Through Chemistry
National Lampoon's Christmas Vacation 2: Cousin Eddie's Island Adventure
Saving Silverman


text:
BA Jewish Studies
At a Glance Admission Requirements Next Steps Affording College Career Outlook Global Opportunities Request Information
Explore Jewish life, history, and culture by examining topics like religious and spiritual values and political and philosophical viewpoints. Study the history and modern life of the Jewish religion while developing an understanding of Jewish contributions to Western civilization.
The BA in Jewish studies offers a transdisciplinary, cross-cultural program of study focusing on the study of Judaism, defined as the civilization of the Jews. It considers Jewish history and modern life and facilitates enhanced cultural awareness and a global perspective.
As with other degree programs in the humanities, a bachelor's degree program in Jewish studies can provide a balance to studies in contemporary science and technology.
Students choose a thematic concentration from history and society, literature and culture, or religion and thought.
Required Courses (Major Map)
Major Map on-campus archive
What if: See how your courses can be applied to another major and find out how to change your major.
At a Glance: program details
Tempe campus
Additional Program Fee: Yes
Second Language Requirement: Yes
First Required Math Course: MAT 142 - College Mathematics
Math Intensity: General
All students are required to meet general university admission requirements.
Freshman Transfer International Readmission
Transfer Options
ASU is committed to helping students thrive by offering tools that allow personalization of the transfer path to ASU. Students may use the Transfer Map search to outline a list of recommended courses to take prior to transfer.
ASU has transfer partnerships in Arizona and across the country to create a simplified transfer experience for students. These pathway programs include exclusive benefits, tools and resources, and help students save time and money in their college journey. Students may learn more about these programs by visiting the admission site: https://admission.asu.edu/transfer/pathway-programs.
Change of Major Requirements
A current ASU student has no additional requirements for changing majors.
Students should refer to https://changingmajors.asu.edu for information about how to change a major to this program.
Flexible Degree Options
Accelerated program options
This program allows students to obtain both a bachelor's and master's degree in as little as five years.
It is offered as an accelerated bachelor's and master's degree with:
Global Management (Creative Industries and Design Thinking), MGM Global Management (Digital Audience Strategy), MGM Global Management (Global Affairs), MGM Global Management (Global Business), MGM Global Management (Global Development and Innovation), MGM Global Management (Global Digital Transformation), MGM Global Management (Global Entrepreneurship), MGM Global Management (Global Health Care Delivery), MGM Global Management (Global Legal Studies), MGM Global Management (Nonprofit Leadership and Management), MGM Global Management (Public Administration), MGM Global Management (Public Policy), MGM Global Management (Sustainability Solutions), MGM Global Management (Sustainable Tourism), MGM Global Management, MGM
Acceptance to the graduate program requires a separate application. During their junior year, eligible students will be advised by their academic departments to apply.
Next Steps to attend ASU
Learn about our programs
Estimate tuition and fees
Find financial aid
Students who receive a bachelor's degree in Jewish studies and pursue a career with one of the hundreds of U.S. companies that do business in Israel have a competitive edge because of their familiarity with Jewish culture. Jewish studies graduates are also prepared to:
attend rabbinical seminary in preparation for becoming a community rabbi or chaplain
engage in world political and economic issues
pursue advanced education in Jewish professional service fields
The degree also provides a firm foundation for students who wish to pursue advanced degrees related to their area of interest in fields that may include:
justice studies
Example Careers
Students who complete this degree program may be prepared for the following careers. Advanced degrees or certifications may be required for academic or clinical positions. Career examples include but are not limited to:
Growth: 14.3%
Median Salary*: $51,760
Growth: 9.3%
Cultural Studies Professor
Growth: -1.4%
Median Salary*: $119,250
Religion Professor
Religious Leader
* Data obtained from the Occupational Information Network (O*NET) under sponsorship of the U.S. Department of Labor/Employment and Training Administration (USDOL/ETA).
Bright Outlook | Green Occupation
With over 250 programs in more than 65 countries (ranging from one week to one year), study abroad is possible for all ASU students wishing to gain global skills and knowledge in preparation for a 21st-century career. Students earn ASU credit for completed courses, while staying on track for graduation, and may apply financial aid and scholarships toward program costs. https://mystudyabroad.asu.edu
Program Contact Information
If you have questions related to admission, please click here to request information and an admission specialist will reach out to you directly. For questions regarding faculty or courses, please use the contact information below.
SHPRSAdvising@asu.edu
Concurrent degree programs are specially designed academic programs which provide high-achieving undergraduate students the opportunity to complete two distinct but complementary bachelor degrees at the same time. Students must meet minimum admissions standards for both programs and be accepted individually by both colleges offering the concurrent program.
Students pursuing concurrent degrees earn two distinct degrees and receive two diplomas. ASU offers students two ways to earn concurrent degrees: by choosing a predetermined combination or creating their own combination. Predetermined combinations have a single admissions application and one easy to follow major map. To add a concurrent degree to your existing degree, work with your academic advisor. Either way, concurrent degrees allow students to pursue their own personal or professional interests.
Accelerated bachelor's and master's degree programs are designed for high-achieving undergraduate students who want the opportunity to combine undergraduate coursework with graduate coursework to accelerate completion of their master's degree. These programs feature the same high-quality curriculum taught by ASU's world-renowned faculty.
ASU students may accelerate their studies by earning a bachelor's and a master's degree in as little as five years (for some programs) or by earning a bachelor's degree in 2.5 or 3 years.
Accelerated bachelor's and master's degree programs are designed for high-achieving undergraduate students who want the opportunity to combine undergraduate coursework with graduate coursework to accelerate completion of their master's degree. These programs, featuring the same high-quality curriculum taught by ASU's world-renowned faculty, allow students to obtain both a bachelor's and a master's degree in as little as five years.
Accelerated bachelor's degree programs allow students to choose either a 2.5- or a 3-year path while participating in the same high-quality educational experience of a 4-year option. Students can opt to fast-track their studies after acceptance into a participating program by connecting with their academic advisor.
This is only the first required math course. This program may contain additional math courses; See Major Map for details.
The level of intensity represents a measure of the number and academic rigor of math courses required.
The level of intensity represents a measure of the number and academic rigor of math courses required. Courses included in the General level: MAT 142
The level of intensity represents a measure of the number and academic rigor of math courses required. Courses included in the Moderate level: MAT 117, MAT 119, MAT 170, MAT 210, SOS 101, CPI 200
The level of intensity represents a measure of the number and academic rigor of math courses required. Courses included in the Substantial level: MAT 251, MAT 265. MAT 266, MAT 267, MAT 270, MAT 271, MAT 272, MAT 274, MAT 275


text:
Harry Potter and the Goblet of Fire Courage
RITA: Hello. I'm Rita Skeeter. I write for the Daily Prophet. But of course you know that, don't you? It's you we don't know. You're the juicy news. What quirks lurk beneath those rosy cheeks? What mysteries do the muscles mask? Does courage lie beneath those curls? In short, what makes a champion tick?
Rita is the wizarding world's version of a slimy tabloid journalist. She's looking for basically anything sensational she can put into her article, and kind of trying (by making it a question) to plant the seed that Harry might not be super-brave. We know otherwise, though, of course.
DUMBLEDORE: The winner is Mr. Diggory who showed innate command of the Bubble-Head Charm. However, seeing as Mr. Potter would have finished first had it not been for his determination to rescue not only Mr. Weasley, but the others as well, we've agreed to award him second place for outstanding moral fiber!
Harry has just proven himself super brave and selfless by saving Fleur's sister in addition to Ron as part of the second task in the tournament, even though it slowed him down getting to the finish line. Who says nice guys finish last? In this case, one finished second.
CEDRIC: You know, for a moment there, I thought you were going to let it get me.
HARRY: For a moment, so did I.
CEDRIC: Some game, huh?
HARRY: Some game.
As Dumbledore warned Harry, the maze kind of changes you, and Harry almost decides to save himself/go for the cup rather than help Cedric when the maze is about to swallow him up. Luckily, he shakes off the maze's evil influence and saves Cedric, proving that he's still the strong, brave boy we always knew he was (we didn't doubt it for a second, Harry, promise).
WORMTAIL: I returned.
VOLDEMORT: Out of fear, not loyalty.
Wormtail is, like, the opposite of Harry and Cedric; he does everything out of fear or to gain, without a thought (apparently) about whether it's right. He's clearly terrified of the Dark Lord, and so he's done things like kill Harry's parents and Cedric, steal Harry's blood to bring Voldemort back to life…you know, normal stuff that friends ask you to do.
VOLDEMORT: After tonight, if they speak of you, they'll speak only of how you begged for death. And I, being a merciful Lord, obliged.
In addition to just plain killing Harry, Voldemort is super excited about making Harry look like a coward who begged for his life.
DUMBLEDORE: In light of recent events, the bonds of friendship we've made this year will be more important than ever. Remember that, and Cedric Diggory will not have died in vain. You remember that, and we'll celebrate a boy who was kind and honest, and brave and true, right to the very end.
Cedric was definitely brave. After all, he definitely put himself at risk to help Harry when a bewitched Krum was after him. Too bad we won't be seeing more of him, since we really think he and Harry would have been good friends (well, er, aside from the whole love triangle with Cho thing).
DUMBLEDORE: Dark and difficult times lie ahead. Soon we must all face the choice between what is right and what is easy. But remember this: You have friends here. You're not alone.
So, yeah, we've seen what "Doing what is easy" looks like: that's Wormtail, who repeatedly fails to stand up to the Dark Lord when tasked with doing nasty things. Bravery, Dumbledore suggests, is being willing to do what is hard, if it's the right thing. Let's hope Harry and his friends are up to the task.


As CEO, Brittany has built a high quality, ethical, and cutting edge addiction treatment facility. As a native Floridian, and graduate of Florida Atlantic University, it was important to Brittany that the knowledge she's gained through her many years in recovery be used to create a cost effective option for those in need of treatment in Florida. Her unique approach to recovery seamlessly blends compassion, motivation, and accountability. Brittany believes that addiction doesn't affect only the addict, but rather, the entire family. She's molded a clinical modality that engages both patient and family to truly facilitate long-term recovery. Her passion is helping men and women engage with the underlying issues that drove them to drugs and alcohol in the first place. Keeping this in mind, Brittany set out to create a clinically driven, comprehensive, addiction treatment center. It's safe to say that her passion and unrelenting drive to help those still struggling with addiction has helped Brittany to make Lighthouse Recovery Institute a truly one of a kind and highly effective treatment center.
After graduating from Florida Atlantic University with a B.A. in Criminal Justice, Jessica completed two separate Master's Programs at Nova Southeastern University. She has an MS in both Investigative Forensic Technology & Behavioral Sciences and Mental Health Counseling. Following her extensive education, Jessica worked at Coral Springs Elementary School, Passport Preschool, the Florida Department of Children and Families, and Broward Youth Treatment Center. To say she has a passion for helping at-risk individuals is an understatement. Her dedication to contributing to the education of others, whether in an academic or treatment setting, is unmatched. Also being committed to health, wellness, and nutritional counseling services, it is plain to see Jessica is one of the most well-rounded, innovative therapists in south Florida and a true asset to Lighthouse's clinical team.
Tabitha has been working in substance abuse treatment in South Florida since 2013. Her previous work experience was primarily focused on the areas of providing clinical support for caseloads under a primary therapist and auditing charts for accrediting bodies. Her passion and dedication to helping others realize their true potential in times of adversity started at a young age and continues to show through her therapeutic work with patients today. Tabitha understands the impact of trauma and addiction on the individual. She strives to empower her patients' recovery by displaying unconditional positive regard and providing truly individualized care with each patient. She received her B.A. in Psychology from Florida Atlantic University in 2014. Following graduation, she completed two years in the FAU Mental Health Counseling graduate program. After determining that it better reflected her personal and professional goals, Tabitha shifted her educational focus and enrolled in the Master of Social Work curriculum. Tabitha graduated from FAU with her MSW in 2018 and is actively pursuing her licensure. In addition to her work in substance abuse treatment, Tabitha completed one of her master's level internships in a facility providing counseling for individuals with disabilities who were been victims of various forms of crime and violence. Tabitha brings a diverse background and a passion for empowering patients, and we are excited to have her as aprimary therapist at Lighthouse Recovery Institute.
Rachael Bass is the executive assistant to the CEO and Directors of Lighthouse Recovery Institute. She assists in the facilitation and execution of administrative responsibilities throughout Lighthouse Recovery Institute. Rachael joined the Lighthouse Recovery Institute in 2015 bringing with her extensive experience in customer service, administrative, and operational procedures. Rachael is proficient in Microsoft Office. She holds an associate's degree in business and is an Intuit Quick Books adviser.
Nety is the first voice you hear when you call Lighthouse Recovery Institute. She has been working in the Mental Health and Substance Abuse field since 2014. Nety carries with her several years of Customer Service Experience and has vast knowledge in Administration. She is Bilingual to English and Spanish and likes helping people. On her spare time Nety enjoys being with family and friends, loves animals, music and the beach.
With over 30 years as a Mental Health Registered Nurse, Randy brings extensive experience to the Lighthouse Recovery Institute's clinical team. She served as a Nurse Manager for both a Detox Program and for inpatient Mental Health Units for Adults, Adolescents and Children. Randy is also certified by the American Nurses Credentialing Center as a Psychiatric Mental Health Nurse. In addition, she is a respected educator for professionals, community members, and families. Areas of knowledge that Randy specializes in include Suicide Prevention, Mental Health Awareness, Addiction and the Family, and Parenting. Aside from Randy's strong clinical background, she is also the mom of a young adult with Substance Use Disorder who has been in long term recovery for over 6 years. Randy is especially passionate about supporting other families on this difficult journey. She is very comfortable sharing her experience, strength, and hope with family members of patients in our care. Randy truly understands the critical importance of a parallel recovery program for family members.
Zoey, a young and ambitious Golden Retriever, is Lighthouse's official emotional support animal. She has been a great asset to the team since her birth in December of 2015. Since then she has been bringing smiles to everyone that walks through the door. She is officially house broken and is currently working on her doggy bone management certification.


text:
Q: Validate ActiveRecord models have same association / group So I am trying to get my head around a custom validation on two ActiveRecord models. The application I am working on contains 3 models; a note, a writer and a notebook. Whenever I create a note through a form, I want to validate that it has the exact same notebook as the writer is currently allowed to work on when created or updated.
The models look really simplified like this;
class Notebook < ApplicationRecord
   has_many :notes
   has_many :writers
end

class Writer < ApplicationRecord
   has_many :notes
   belongs_to: notebook
end

class Note < ApplicationRecord
   belongs_to: writer
   belongs_to: notebook
end

So whenever I do something like this;
another_notebook = Notebook.new

writer = Writer.new

note = Note.new(writer: writer, notebook: another_notebook)
note.save!

A validation error is thrown as the writer and the notebook do not have an association with each other.

A: First just start off by creating indirect assocations:
class Notebook < ApplicationRecord
   has_many :notes
   has_many :writers, through: :notes
end

class Note < ApplicationRecord
   belongs_to: writer
   belongs_to: notebook
end

class Writer < ApplicationRecord
   has_many :notes
   has_many :notebooks, through: :notes
   # ...
end

This creates a many-to-many association between Notebook and Writer.
If you then want to add rule that the writer can only create notes in a specific notebook:
class Writer < ApplicationRecord
   has_many :notes
   has_many :notebooks, through: :notes
   belongs_to :current_notebook, class: 'Notebook'
end

class Note < ApplicationRecord
  # ...
  validate :is_current_notebook

  def is_current_notebook
    unless notebook == writer.current_notebook
      errors.add(:notebook, 'is not valid.')
    end
  end
end

However I would consider if this actually is a good fit for a model validation as it seems like more of a authorization issue that should be handled by CanCanCan or Pundit and not an issue of bad user input which is what validations should handle.


For the past few years, Nintendo has been at odds with creative communities with its strict guidelines for video content creation, particularly on YouTube, with a great deal of controversy surrounding its Creators Program. Starting next year, however, things are about to get a lot better.
Nintendo has announced today that its controversial Nintendo Creators Program will be closing at the end of December. The Nintendo Creators Program is a revenue-sharing program in which YouTube channels can apply to have their videos or channels approved by Nintendo, and receive a portion of the revenue, with Nintendo receiving the rest. Its announcement in 2015 drew the ire of many video content creators, who argued that it only aimed to stifle the creativity of those who focused primarily on Nintendo content by forcing strict guidelines on the games that can be covered and the type of content that can be produced.
The program drew further anger in 2017, when it was announced that members of the Creators Program would no longer be able to livestream on YouTube if their channels were registered, requiring them to either stream from a channel that wasn't registered or quit the program altogether — both of which could lead to a total loss in advertising revenue. That decision, and indeed the program as a whole, has largely been seen as backwards and out-of-touch, so Nintendo's decision to close it is a positive step forward for the company.
Alongside the announcement of the cancellation of the program was a new list of content creation guidelines, which present a fair and reasonable set of rules for content creators within the bounds of current copyright law. In short, they allow you to make and monetise any sort of transformative content, including Let's Plays, video reviews, livestreams, and basically anything else that has your creative input. It does not, however, allow the uploading of existing Nintendo videos, such as trailers and Directs, or content ripped from games like music soundtracks. It also explicitly forbids any content featuring pre-release or pirated content, which is no doubt a measure introduced to combat the early leaks of recent titles like Super Smash Bros. Ultimate and Pokemon Let's Go.
We're making it easier for creative fans to show their love for Nintendo and monetize videos that include Nintendo game content.
You can read the full guidelines below, or click here to read the accompanying FAQs.
We are humbled every day by your loyalty and passion for Nintendo's games, characters and worlds, and respect that you want to be able to express yourself creatively by sharing your own original videos and images using content from our games.
You are only permitted to use Nintendo Game Content that has been officially released, or from promotional materials officially released by Nintendo (such as product trailers or Nintendo Directs).
If you want to use the intellectual property of a third party, you are responsible for obtaining any necessary third-party permissions.
We reserve the right to remove any content that we believe is unlawful, infringing, inappropriate, or not in line with these Guidelines.
Please understand that we will not be able to respond to individual inquiries regarding these Guidelines. Also, we may update these Guidelines from time to time, so please refer to the latest version before sharing your content.


Get an alert with the newest ads for Motorcycle Parts & Accessories in Sarnia.
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I have a pair of MSR youth size 5 Motorcross/MX Boots. They were used for two seasons. $50 obo I live in Petrolia but travel to Sarnia frequently.
This original Italian spec pamphlet would be a wonderful addition to your classic motorcycle documentation portfolio.
This original french spec pamphlet will be a nice addition to your classic motorcycle documentation.
Low profile backrest , complete package. Came off a Dyna/Superglide. Perfect condition. $185 or best offer.
I have a size 48 Harley - Davidson Leather Vest , Spotster Badged.
No longer required. Best offer takes them.
This is a clutch lever from a very early small displacement Honda. May be rare. In excellent condition. Complete with steel bushing. Lightweight and small so can mail for 2 or 3 dollars.
Corbin seat for 94-97 Honda VFR 750. Great shape with one little tear as shown in picture. Serious inquiries only please.
Post your classified or want ad in Sarnia Motorcycle Parts & Accessories. It's fast and easy.


text:
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Home » Meet the PHCCCONNECT2020 keynote speakers
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Meet the PHCCCONNECT2020 keynote speakers
The virtual event will be held Sept. 30 – Oct. 1.
KEYWORDS education / PHCC / PHCC CONNECT
This year's annual PHCCCONNECT conference will feature two keynote speakers: U.S. Army Lt. Gen. Russel L. Honoré (retired) and Nathan Gonzales, editor and publisher of Inside Elections with Nathan L. Gonzales.
Honoré's presentation is titled, "Resilient leadership: Prepare today, prevail tomorrow" and will take place on Wednesday, Sept. 30 from 11:30 a.m. – 1 p.m. EDT.
In our country's new normal, he provides audiences with impactful takeaways as change and unpredictability are constants and resilience is mandatory.
An American hero who helped New Orleans recover from catastrophe, he now shares candid and colorful leadership views on how government resources, the private sector and individuals can work together to overcome the challenges brought on by the Coronavirus pandemic.
As the commander of Joint Task Force Katrina, Lt. Gen. Honoré became known as the "Category 5 Gen." for his striking leadership style in coordinating military relief efforts in post-hurricane New Orleans. He is a decorated 37-year Army veteran and global authority on leadership.
News networks like CNN, FOX, MSNBC and CBS consider him their go-to expert on emergency and disaster preparedness, as well as crisis management. He also is the author of three books, including his most recent, "Don't Get Stuck on Stupid!"
Gonzales' presentation "The November elections and beyond: Analysis and predictions" takes place Thursday, Oct. 1from 11:50 a.m. – 1 p.m. EDT.
He is the editor and publisher of Inside Elections with Nathan L. Gonzales, which provides non-partisan analysis of campaigns, from congressional to gubernatorial to presidential.
He was an editor, analyst and writer for The Rothenberg Political Report for more than 13 years before taking over the company in 2015. He offers audiences some of the most detailed electoral forecasting in the business.
He regularly can be seen on CNN discussing the latest in politics, as well as offers his expertise to the New York Times, The Washington Post, The Wall Street Journal and USA Today. On Election Night 2016, Gonzales was an on-air analyst for "Newshour" on PBS. Prior to that, he worked as an off-air consultant for ABC News on its Election Night Decision Desk for 14 years.
Source: PHCC
Meet the keynote speakers at PHCC CONNECT 2019
PHCCCONNECT2020's virtual event
PHCCCONNECT2020 goes virtual
The New Flat Rate's Danielle Putnam presents keynote celebrating women in the trades
John Siegenthaler: Chump change
The Glitch & The Fix: Busy backup
Dan Holohan: How vacuum can cause steam problems
PHVAC experts look ahead in 2021
Dave Yates: Vented or vent-free gas logs and heaters
The January 2021 issue of Plumbing & Mechanical features the 2021 Plumbing Industry Forecast. This issue also looks at how specialty contractors can drive collaboration and project quality, and much more!
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HMS Tiptoe, where are you now?
HMS Tiptoe was a Vickers Armstrong built submarine launched in 1944. The Admiralty didn't much care for Tiptoe's name, but Winston Churchill did, and he got his way. She had plenty of time to get involved in the Pacific war, operating out of Australia, and had sunk a number of Japanese cargo ships. The ship was banged up plenty during the war, from depth charges and such, but got most of the dents in her hull from after the war. In 1955 a coastal steamer, Nordlys, crashed into her after first hitting a British destroyer in Tromso harbour. In 1964 she ran aground in the Firth of Clyde due to fog. And in 65 she ran into HMS Yarmouth.
In 1967, Tiptoe was the oldest British submarine still in service, and when decommissioned in 1969 she was the last Triton class submarine left, a design from the 1930's. She was one of the first to have an all welded hull, which increased her depth to 350 ft, but was one of the last to have external torpedo tubes. She was sent to a scrapyard in 1975 in Plymouth harbor, most likely where Steve Johnson found her.
Steve Johnson is on a mission. He doesn't want the UK's history to disappear and is documenting and saving everything he can and posting it on the web. He has his work cut out for him, however, though he seems up to the task. When Geocities disappeared, a lot of his stuff did too, but he seems to continue finding servers with space and keeps coming back. He ran across some old rusting British submarines one day back in the 80's, and only got pictures with a promise of not divulging their location, but it was most likely in Plymouth. The Tiptoe has undoubtedly been turned into consumer goods by now, and in that sense does have a bit of immortality. Nothing really ever goes away.


Whilst we encourage our patients to come to the surgery, where we have the proper equipment and facilities available, we do appreciate this is not always possible. In this respect, if you do need a home visit, you can help us by calling reception before 10:30. Some non-urgent requests received after 10:30 may not be seen until the next working day.


Last night I had a dream that I was getting dressed to go to see the doctor. I knew I was sick, but the nature of this illness was hidden. I walked into the bathroom, glanced at the mirror and saw my reflection not where I stood, but behind me in the shower. When the fogged door opened there I was, dripping wet and sitting on a plastic chair. I did not get up, but instead called out a name.
I sat there, strands of white hair spilling over my ears, my chest sunken, my bony knees protruding like the roots of a cypress tree.
Gazing into the mirror, I saw myself as an old man.
After what seemed to be a tedious wait, a young woman came in and helped me out of the shower. She brought me a towel and a walker and I shuffled off, carefully eyeing the tiled floor in front of me. My name was written on the towel in black magic marker. The walker had yellow tennis balls stuck on the bottom of its metal legs. Neither she nor I spoke a word.
I then left the vision in the mirror and walked downstairs and out to the garage, where I climbed into my car and backed out into the driveway. Just as I started out I braked and looked into the rear-view mirror. I could see the oak tree in my back yard. Sunshine dropped through the shadows of the immense branches and formed a patchwork on the grass, and the leaves fussed from the breeze.
There were people walking all over the lawn.
I saw my son tossing a ball to a little boy in shorts, while two older girls sat gossiping under the tree. They called out "Father!" and he turned. He looked the same age as I am now, his hair dappled with gray. My wife and daugher stood nearby talking. My little girl was tall and tanned, and as she spoke my wife handed her a feisty-looking baby.
I peered into the small rectangle for several minutes, but never did catch a glimpse of anyone who looked like me. The last thing I remember before awakening was driving off down the road, unable to release even a sigh. The streets passed by silently, and I encountered no other cars on the desolate road.
What does the future hold for us? Will we cheat death for so long that we outlive the life we begged for, or will we instead be harvested early, spared from any further rendezvous with the lash? Such thoughts are but fantasies found in dreams - except for those living with cancer. For them speculation is not a phantasm. It is a daily reality thrust upon them, like an uninvited guest at the table. We who live without such a burden can honor those who do by remembering that unless one respects the future as the gift it is, waiting for it is pointless; it is worthless; it is absurd.
Death is inevitable whether we like it or not. If we can celebrate birth why not celebrate death also. This is greatest insecurity we have.
Pain, especially pain of the disease like cancer etc. is intense and depressing with no hope, nothing to look forward to.
But great are human beings. They evolve some mechanism to cope with all the distress, frustation and pain. So powerful is the mind that one can relax and enjoy even worst of our times. Accept death and accept the way it will come to each one of us. Suddenly you are at peace with yourself.
It is not repression but intense awareness.It is acceptance.
There is no waiting for tomorrow but ecstacy and happiness is right here even for people suffering from most dreaded diseases. Only method is higher mental and emotional consciousness.
There are those of us who are ill but do not face death... We face life with illness as a companion. Your piece seems to me especially fitting in that setting, where it is easy to fall into self-pity and nonfunction. Your words are a stiff reminder.
Hey, would you mind if I printed this up and used it as a study in how small, subtle details in writing can create an entire scene? Many of the little things you mentioned -such the tennis balls on the walked and the dapples of gray in the father's hair - come together to create a poignant portrait in words. This is the kind of piece that makes me shake my head and say, "Now why can't I write like that?"
And the timing of this piece, along with Kay's and Bronwyn's comments couldn't be better for me. I seem to have run afoul of some immortality seekers lately, so the more mature and insightful views of life are very refreshing.
Bronwyn ... I had the same reaction you did. Living with Myasthenia Gravis and Lupus combined ... it would be very easy to give into the diseases ... and who would blame me. But to give into the disease ... means living in depression... I'd rather fight the depression, but some days, I just need a reminder that there is more to my life than doctor's offices, blood tests and physical therapists.
moving...so well written. you draw me in every time.
Your writing is astonishing. I love your posts and I will continue to read them intil you decide to stop.
Nice blog you've got here Craig! Keep it up.
Hi Craig! I just wanted to tell you that I've linked your nice blog.
great post, with the humble sentiments well-appreciated!
Great blog i have a dreams It relates to dreams stuff. Come and see when you get time.


text:
The library book
The work The library book represents a distinct intellectual or artistic creation found in Coweta Public Library System. This resource is a combination of several types including: Work, Language Material, Books.
The Resource The library book
by Susan Orlean
trueOrlean, Susan
trueArson
Arson -- California | Los Angeles -- History -- 20th century
trueArson investigation
trueBooks
trueFires
Fires -- California | Los Angeles
HISTORY / Social History
HISTORY / United States / 20th Century
trueLibrarians
trueLibraries
trueLibraries -- Fires and fire prevention
trueLibraries -- Social aspects
trueLibrary materials
trueLibrary science
Los Angeles Public Library -- Fire, 1986
Los Angeles Public Library, Central Library -- Fire, 1986
Los Angeles Public Library, Central Library -- History
trueLos Angeles, California -- History
Public libraries -- California | Los Angeles -- History
Public libraries -- California | Los Angeles -- History -- 20th century
"Susan Orlean reopens the unsolved mystery of the most catastrophic library fire in American history, and delivers a dazzling love letter to a beloved institution--our libraries"--
"Orlean chronicles the LAPL fire and its aftermath to showcase the larger, crucial role that libraries play in our lives; delves into the evolution of libraries across the country and around the world, from their humble beginnings as a metropolitan charitable initiative to their current status as a cornerstone of national identity; brings each department of the library to vivid life through on-the-ground reporting; studies arson attempts to burn a copy of a book herself; reflects on her own experiences in libraries; and reexamines the case of Harry Peak, the blond-haired actor long suspected of setting fire to the LAPL more than thirty years ago"--
"On the morning of April 28, 1986, a fire alarm sounded in the Los Angeles Public Library. As the moments passed, the patrons and staff who had been :fi cleared out of the building realized this was not the usual false alarm. As one fireman recounted later, "Once that first stack got going, it was 'Goodbye, Charlie." The fire was disastrous: it reached 2000 degrees and burned for more than seven hours. By the time it was extinguished, it had consumed four hundred thousand books and damaged seven hundred thousand more. Investigators descended on the scene, but more than thirty years later, the mystery remains: Did someone purposefully set fire to the library--and, if so, who? Weaving her lifelong love of books and reading into an investigation of the fire, award-winning New Yorker reporter and bestselling author Susan Orlean delivers a mesmerizing and uniquely compelling book that manages to tell the broader story of libraries and librarians in a way that has never been done before. In The Library Book, Orlean chronicles the LAPL fire and its aftermath to showcase the larger, crucial role that libraries play in our lives; delves into the evolution of libraries across the country and around the world, from their humble beginnings as a metropolitan charitable initiative to their current status as a cornerstone of national identity; brings each department of the library to vivid life through on-the-ground reporting; studies arson and attempts to burn a copy of a book herself; reflects on her ovsm experiences in libraries; and reexamines the case of Harry Peak, the blond-haired actor long suspected of setting fire to the LAPL more than thirty years ago. Along the way, Orlean introduces us to an unforgettable cast of characters from libraries past and present--from Mary Foy; who in 1880 at eighteen years old was named the head of the Los Angeles Public Library at a time when men still dominated the role, to Dr. C.J.K. Jones, a pastor, citrus farmer, and polymath known as "The Human Encyclopedia" who roamed the library dispensing information; from Charles Lummis, a wildly eccentric journalist and adventurer who was determined to make the L.A. library one of the best in the world, to the current staff, who do heroic work every day to ensure that their institution remains a vital part of the city it serves. Brimming with her signature wit, insight, compassion, and talent for deep research, The Library Book is Susan Orlean's thrilling journey through the stacks that reveals how these beloved institutions provide much more than just books--and why they remain an essential part of the heart, mind, and soul of our country. It is also a master journalist's reminder that, perhaps especially in the digital era, they are more necessary than ever."--Dust jacket
trueDramatic
trueCompelling
trueRichly detailed
trueWitty
Booklist Editors' Choice, 2018.
LibraryReads Favorites, 2018.
New York Times Notable Book, 2018
LBSOR/DLC
Z733.L8742
O75 2018
Context of The library book
The library book, by Susan Orlean

 Data from The library book - Coweta Public Library System

Data Citation of the Work The library book