text:
This is what a rebuild looks like and Bulldogs fans must stay the course: Round 14 Match Report
As most of you know, each week I compile a review of the Canterbury-Bankstown Bulldogs' NRL match and share it among fans.
It is a labour of love born of a lifelong commitment to the club.
This week's report is a little different. The Bulldogs were crushed by the Roosters on Sunday afternoon at the Sydney Cricket Ground. Crushed 38-12 thanks to a vast difference in class and talent within the playing rosters.
Easts played the match without Luke Keary, James Tedesco and Jared Waerea-Hargreaves. Despite that problematic situation, Boyd Cordner, Latrell Mitchell, Cooper Cronk, Daniel Tupou and Angus Crichton led from the front and outclassed the Dogs.
That list says it all.
After another disappointing loss and a seven tries to two demolition, Bulldog's fans need to face the simple and hard reality that Canterbury-Bankstown has potentially the weakest and most shallow roster in the NRL.
2019 has seen an ever-increasing level of frustration and anger around the performance of the team, selections and omissions. Sadly, much of the discussion is misguided, ill-informed and unfair on coach Dean Pay and the Board of Directors.
The Bulldogs are in the midst of a significant rebuild off the back of reckless salary cap mismanagement committed by the previous board and coach. It left the club locked into back ended contracts that needed to either be honoured or off-loaded, to free up money for new signings.
Any criticism of the current board is flawed. Just 18 months into a significant rebuild, the course must be stayed. Repairing the damage done is at least a four year proposition.
Manly and Newcastle have lived a similar pain. Count the years from their lowest point and the case studies reveal the realistic time-frame of the difficult road ahead.
Dean Pay has been massacred by some; those intent on questioning his methods and selections. In truth, Pay is somewhat hamstrung without the tools he requires to build a team capable of playing semi-final football.
The team's effort has been consistent. Even against the Roosters on Sunday the side was committed and valiant despite the lop-sided scoreline. Quite simply, the Roosters' squad did exactly what it should do against the Bulldogs.
Pay has been seeking combinations. Sure Adam Elliott, Rhyse Martin, Lachlan Lewis and Corey Harawira-Naera have spent time out of the first grade squad.
Yet to this point, nothing has clicked or gelled. Have all his decisions been correct? Perhaps not, yet he has rotated his players; looking at them with an eye to the future.
That approach brought the wonderfully raw young talent Jayden Okunbor into first grade, as it did with Nick Meaney and Jack Cogger. All three have done well, with Okunbor a potential star on the wing.
Chris Smith looks to be the latest player to stake a long term claim for a spot in the Bulldog's squad.
The challenge for the blue and whites is to now rebuild that squad; maintaining the best of it and sourcing the required missing pieces over the next 18 months.
After the tough and necessary decisions involving the Morris twins, Moses Mybe, Aaron Woods, David Klemmer and the retirement of Greg Eastwood, the squad was stripped of experience.
Moreover, the failure of the previous board and coach to recognise the talents of Damien Cook, Shaun Lane, Dale Finucane and Corey Thompson also lies at the heart of Canterbury's current situation.
It is a situation that can and will be fixed, yet time is the enemy when it comes to rebuild and recovery in the NRL.
The quality and expertise of the people charged with rebuilding the Bulldogs will ensure they eventually get the job done. For it to have happened by now is an unreal expectation.
Stay the course and prepare to see Reimis Smith and Jayden Okunbor in full flight on the end of a slick Bulldog back line in the near future.
Look out for Ofahiki Ogden's continued development up front and get excited about our new additions Joe Stimson and Dallin Watene-Zelezniak.
With Kieran Foran now delivering exactly what the club signed him for and Nick Meaney looking likely to blossom into an accomplished first grade player, there are shoots of hope.
Sticking around to see those shoots bloom will be the most satisfying part of the entire experience . It will require a little pain, patience and progress.
The club has been to the cellar and the return to the penthouse is going to take some time yet.
Joanne pethers
17.06.2019 at 06:40 Reply
When is Lachlan Lewis coming back
Not sure Joanne but Pay was looking for some better attacking options and Cogger was playing very well. Not sure what his next move will be.
Ian N Reid
Great report. I support your comments. Sadly, a lot of people require instant gratification. Its just not going to happen.
It will take time as you have suggested. The current roster is high on enthusiasm, but sadly low on talent. When the financial side of the previous mismanagement is settled, a new roster will be assembled. The club has the coach and personnel to create good things. It will take time and people need to be patient.
Like the shampoo add said, it wont happen overnight, but it will happen.
Thanks Ian. Sad that some people fail to see just how young and out classed much of the squad is. Perhaps they should reflect on how many of our boys would crack first grade elsewhere?


text:
the GET Podcast
Institutes & Initiatives
Digital Supply Chain Institute
African Women Entrepreneurship Cooperative
Cyber Readiness Institute
Global Scholars Program
The New Enlightenment Initiative
Applied Corporate Governance Institute
USA Women Entrepreneurship Cooperative
The Data & Trust Alliance
CGE Blog
Bloomberg Wall Street Week
CEO Insights
CGE Highlights Globalization of Platform Business Models at 2016 MIT Platform Strategy Summit
Platform business models have become a global phenomenon with important management implications. This is the conclusion of a global survey of platform companies undertaken by CGE and presented at the MIT Platform Strategy Summit on July 15, 2016. In his keynote address kicking off the summit, Samuel J. Palmisano, Founder and Chairman of The CGE, discussed how "asset light" organizations are leading the platform revolution but that all companies are seeking how to manage the growing intersection of physical and digital worlds. Following Sam's presentation Peter C. Evans, VP and Director of CGE's "Emerging Platform Economy" research, presented the findings from CGE's global survey of platform companies and two new CGE research papers: The Rise of the Platform Enterprise: a Global Survey and The Rise of African Platforms: a Regional Survey.
"The political environment in Europe and the United States may point to a growth in nationalism, but the rapid growth of digital platforms, networks, and data business models in fact represents the latest shift in the forces of globalization," wrote MIT's Sloan School of Business Management of Sam Palmisano's presentation.
Indeed, Sam's keynote speech and many others throughout the day focused on the importance of platforms for startups as well as incumbents. While platforms allow companies to scale and grow at unprecedented speeds, they also present a myriad of challenges such as managing in a multi-sided market and cyber-security risks.
"Platform companies are becoming an important part of national systems of innovation. The world's largest platform companies are not only earning more patents but are seeding whole ecosystems of startups in cutting-edge areas of machine learning and artificial intelligence," said Peter Evans. "While, platforms have traditionally been associated with industries like e-commerce and mobile payments," he added, "energy, health-care and the public sector are ripe for innovation – the platform enterprise will be a fascinating space of business to watch in the coming years."
Back to News and Press
745 5th Ave, Suite 500, NY, NY 10151
© 2022 The Center for Global Enterprise. All rights reserved

redpajama_set_name: RedPajamaCommonCrawl


text:
ART WORLD NEWS
Artist Emil Nolde's Nazi Past Scrutinized in Exhibition in Berlin -ARTnews
Emil Nolde, Kriegsschiff und brennender Dampfer (Warship and Burning Steamer), undated (ca. 1943), watercolor. DIRK DUNKELBERG, BERLIN/©NOLDE STIFTUNG SEEBÜLL
On November 9, 1933, German artist Emil Nolde attended what he considered his most important networking event to date: a dinner party with Adolf Hitler commemorating the 10th anniversary of the Beer Hall Putsch, the failed coup in which some 2,000 Nazis in Munich attempted to seize power from the Bavarian government. "The Führer is great and noble in his aspirations and a genius man of action," Nolde wrote in a letter to a friend after the soiree, noting that Hitler "is still being surrounded by a swarm of dark figures in an artificially created cultural fog." The "dark figures" to which he referred were Jewish Germans who, the artist believed, sought to destroy what he considered "pure" German art through cultural diversity.
Nolde, then 66 years old, was aware that he was a test case for Hitler and his sycophantic propaganda minister, Joseph Goebbels. Revered as a founding father of 20th-century German Expressionism, he had nonetheless generated controversy among Nazi elites for respectfully depicting a wide variety of subjects, including ethnic minorities. He did not paint in the hyperrealistic style that Hitler preferred, favoring instead bold brushstrokes and electrifying colors to evoke visceral feelings of primal passion.Emil Nolde in Munich, 1937. HELGA FIETZ/© NOLDE STIFTUNG SEEBÜLL
But Nolde was determined to enter Hitler's good graces. A year after meeting at the dinner party, he wrote an autobiography modeled on Hitler's Mein Kampf—with Nolde's titled Jahre der Kämpfe (or Years of Struggle, using the plural of "Kampf"). And he advocated eugenics: "Some people, particularly the ones who are mixed," he wrote in his book, "have the urgent wish that everything—humans, art, culture—could be integrated, in which case human society across the globe would consist of mutts, bastards and mulattos."Nolde's attempts to ingratiate himself with the genocidal Nazi regime did not go as planned. Displeased with his Expressionist style, Hitler featured more works by Nolde than any other artist in his notorious 1937 "Degenerate Art" exhibition (which included 27 of Nolde's paintings, watercolors, and etchings) and confiscated 1,052 Nolde works from German museums. Stung, the artist retreated to his home in Sebüll, a remote area in Frisia, the northwest region of Germany considered by many Germans to be the cradle of the nation's language and culture. There, Nolde began crafting an image as a persecuted artist that he promoted to the Allies and his fellow Germans after the war.It was a farce that most Germans were happy to entertain. As late as 2013, when historian Manfred Reuther published his official biography Emil Nolde. Mein Leben (Emil Nolde. My Life), the 456-page book omitted any mention of Nolde's admiration for Hitler and condensed World War II to roughly five pages.Emil Nolde's Das Leben Christi, from 1911/12, on view in the Nazi's 1938 exhibition "Degenerate Art" in Berlin. PHOTO: ©ZENTRALARCHIV – STAATLICHE MUSEEN ZU BERLIN; ART: ©NOLDE STIFTUNG SEEBÜLL
After the artist's death, in 1956 at the age of 88, the Nolde Foundation (or Nolde Stiftung in German) worked to hide his racist past. But recently the foundation has started to acknowledge the dark side of history—as evidenced by an exhibition at Berlin's Hamburger Bahnhof museum that opened this summer and remains on view through September 15. "Nolde: A German Legend, the Artist in National Socialism" (the title on display at the museum, as opposed to its online mantle "Emil Nolde. A German Legend. The Artist during the Nazi Regime") is the first attempt by the foundation to break the German public's impression of Nolde as a victim of Hitler's regime rather than an advocate for his anti-Semitic worldview.For many years, Bernhard Fulda and Aya Soika, a husband-and-wife team well-respected in the international art research community and co-curators of the show with Christian Ring, the head of the Nolde Foundation, tread a fine line with Nolde's legacy. Though they have published numerous articles shedding negative light on the artist—most notably a 2014 catalogue essay for an exhibition at Neue Galerie in New York—they have done so with caution. "For decades, the foundation did really sit as gatekeepers on all this archival material," Fulda told ARTnews. "Access to his written legacy has been notoriously difficult."Emil Nolde, Gaut der Rote, undated (ca. 1938), watercolor and India ink. DIRK DUNKELBERG, BERLIN/©NOLDE STIFTUNG SEEBÜLL
That changed when Ring took over in 2013, ending a long history of what Fulda called "the artist's marketing campaign," and the exhibition marks the first time Nolde's racist views have been fully exposed. To expedite the transparency, the exhibition's hefty catalogue has been published in both German and English, a bilingual gesture often avoided with controversial German exhibitions.The show opens with Pentacost (1909), a painting that fueled Nolde's anti-Semitism when it was rejected for an exhibition by the Berlin Secession, an artist group founded in 1898 in opposition to European salons and as a defender of traditional German culture. Nolde was deeply attached to the work depicting the visitation of the Holy Spirit upon Jesus Christ's apostles after their savior's death and resurrection, and after its dismissal he wrote a scathing letter to Berlin Secession president Max Liebermann that leaked to the press, much to Nolde's horror. The episode, according to Fulda and Soika, led Nolde to give serious weight to the idea that Liebermann, a Jewish German, and what Nolde called the "Jewish-dominated" press were subverting true German culture. "Throughout his life Nolde suffered from negative art-criticism," the researchers write in the exhibition catalogue, "and in this anti-Semitic conspiracy theory he found something it could be convincingly attributed to."Rather than deflecting the subject of anti-Semitism by focusing on Nolde's most iconic works, including his nine-part 1912 masterpiece The Life of Christ, the curators chose to focus on art by Nolde that reflects the racist myth of Nordic superiority in which he believed even after the Nazis rejected his work. In 1938, Nolde created the luminous blue and golden watercolor Mistress and Stranger as part of a series celebrating vikings that counted as a failed attempt to have Hitler reconsider his fate when he refused to paint the Nordic subjects in the realistic hues that the Führer preferred. In Three Old Vikings, a trio of warriors are fierce and ready to fight—but unusually colored in fiery burnt orange and saffron. In Veterans, two soldiers stare out with stoic, determined faces and clenched jaws, yet Nolde thwarted his mission once more by painting their skin an odd golden hue.After the war, Nolde touted these and other works as a sign of his bravery against the Nazis—a position thoroughly debunked by the exhibition. A quote from Nolde's wife Ada prominently displayed in the Hamburger Bahnhof boasts that the couple had stood "fully and completely behind our Führer" long after other Germans had denounced him. And a lengthy essay in the catalogue (and excerpted in the exhibition) analyzes the anti-Semitism in Nolde's Jahre der Kämpfe.Emil Nolde, Verlorenes Paradies (Lost Paradise), 1921, oil on canvas. FOTOWERKSTATT ELKE WALFORD, HAMBURG, AND DIRK DARK MOUNTAIN, BERLIN/©NOLDE STIFTUNG SEEBÜLL
"He is an artist we would not normally celebrate: an anti-Semite, someone who joined the Nazi party and who for the rest of his life never apologized," Fulda said. The previously predominant view of Nolde as a wartime victim owed much to the Nolde Foundation's tight grip on his reputation, and it was also influenced, Fulda said, by the fact that many past historians, curators, and journalists might have not wished to offend living relatives who may have been admirers of the Nazi regime themselves.But all the recent research has started to lead to change. Earlier this year, German Chancellor Angela Merkel removed Nolde's Breakers, a striking 1936 seascape, from a prominent place on her office wall. And revelations about the artist's past of the kind on display in Berlin may stand to change thoughts about his work forever. "Whenever people think that art and cultural context are entirely distinct spheres—[that] art is totally autonomous—they are kidding themselves," Fulda said.But Fulda and Soika's role as historical researchers is only part of an equation that includes viewers, too. "We don't pass any judgment in that regard," Fulda said. "We don't say, 'This is what you should do with this cultural context.' We tell art lovers: 'Deal with it—now you figure out how this new knowledge frames the artworks of Nolde that you're seeing.'"
Yuki Kihara to Make Historic Presentation at 2021 Venice Biennale -ARTnews
Novelist Ahdaf Soueif Resigns from British Museum's Board, Citing BP Funding, Labor Issues, More -ARTnews
David L. Lee Elected President of Getty Trust Board -ARTnews
US, China should return to 'serious communication' on trade deal: ex-Beijing official
Bogdan Terzi — the financial expert is writing a book on how to earn and spend money
How marketers are changing agile practices to meet their needs
Peter Saul to Have New Museum Survey in 2020 -ARTnews
Elvira Gavrilova– is the designer for ambitious and self-reliant women
Elizabeth Warren's wealth tax may include a $1 million marriage penalty
Pinterest's new Shop the Look collections lets brands promote several items in one mobile ad
Niki de Saint Phalle, Pioneering French Feminist Artist, to Be Subject of Major Survey at MoMA PS1 in New York -ARTnews
TeleTrade reviews: the expert in doing business in the international financial markets
Are you making these mistakes with your metrics? Here's how to avoid them
Shopify's latest acquisition gives merchants access to advanced fulfillment tech
Copyright 2019 - Designed by Manuel


text:
Opelousas Mayor Reggie Tatum appears in court, seeks grand jury, recall information
Posted: 1:18 PM, Apr 05, 2018
Opelousas Mayor Reginald Tatum / KATC
Opelousas Mayor Reggie Tatum's attorney is set to subpoena the organizers of an unsuccessful recall petition against Tatum and will soon have the names and addresses of who participated in the grand jury that indicted the mayor.
Attorney Frank Olivier III had filed a motion in February for the grand jury information and to subpoena the recall organizers to produce the petition. In a Thursday hearing on those motions, prosecutors posed no objection to the requests.
Olivier said the requests amount to him doing his "homework" before trial in a case he claims is "politically motivated."
"There has been a serious misunderstanding as to what transpired and how it came about," Olivier said after the hearing.
Olivier said he will now obtain the grand jury information from the St. Landry Parish Clerk of Court.
Olivier will also issue a subpoena to recall organizers Derrick Comeaux and Paul Gennuso to produce the recall petition by May 3. The petition would also include the names and addresses of people who declared they wanted Tatum before voters for a recall election.
Comeaux and Gennuso have previously told KATC they no longer have the document.
Olivier said he's also awaiting additional discovery in the case, including information from the Federal Emergency Management Agency, as well as the Governor's Office of Homeland Security and Emergency Preparedness.
Tatum faces multiple charges of theft, forgery and malfeasance related to a nearly $13,000 overtime payment he received after the August 2016 floods. He's also accused of forging time sheets for some council members.
Although Tatum was placed on track for a May trial, Olivier said it doesn't look like that date will happen — although he said he'd like for the proceedings to close before October elections.
"These are all specific intent charges, and let me tell you, my client is honest as the day is long," Olivier said.


I haven't seen anyone from JetBrains on this forum. The .NET blog is also quiet. Has something happened to JetBrains? Oleg mentioned that there would be an EAP by the end of 2008 and I haven't seen him since then. Can somebody from JetBrains give us more information?


text:
##########################################################################
#Aqueduct - Compliance Remediation Content
#Copyright (C) 2011,2012
#  Vincent C. Passaro (vincent.passaro@gmail.com)
#  Shannon Mitchell (shannon.mitchell@fusiontechnology-llc.com)
#
#This program is free software; you can redistribute it and/or
#modify it under the terms of the GNU General Public License
#as published by the Free Software Foundation; either version 2
#of the License, or (at your option) any later version.
#
#This program is distributed in the hope that it will be useful,
#but WITHOUT ANY WARRANTY; without even the implied warranty of
#MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
#GNU General Public License for more details.
#
#You should have received a copy of the GNU General Public License
#along with this program; if not, write to the Free Software
#Foundation, Inc., 51 Franklin Street, Fifth Floor,
#Boston, MA  02110-1301, USA.
##########################################################################

###################### Fotis Networks LLC ###############################
# By Vincent C. Passaro                                                 #
# Fotis Networks LLC	                                                #
# Vincent[.]Passaro[@]fotisnetworks[.]com                               #
# www.fotisnetworks.com	                                                #
###################### Fotis Networks LLC ###############################
#
#  _____________________________________________________________________
# |  Version |   Change Information  |      Author        |    Date    |
# |__________|_______________________|____________________|____________|
# |    1.0   |   Initial Script      | Vincent C. Passaro | 1-Aug-2012 |
# |          |   Creation            |                    |            |
# |__________|_______________________|____________________|____________|
#

#######################DISA INFORMATION##################################
# Group ID (Vulid): V-12016
# Group Title: GEN005220
# Rule ID: SV-37684r1_rule
# Severity: medium
# Rule Version (STIG-ID): GEN005220
# Rule Title: .Xauthority or X*.hosts (or equivalent) file(s) must be
# used to restrict access to the X server.
#
# Vulnerability Discussion: If access to the X server is not restricted,
# a user's X session may be compromised.
#
# Responsibility: System Administrator
# IAControls: ECCD-1, ECCD-2
#
# Check Content:
#
# Determine if the X server is running.
# Procedure:
# ps -ef |grep X

# Determine if xauth is being used.
# Procedure:
# xauth
# xauth> list

# If the above command sequence does not show any host other than the
# localhost, then xauth is not being used.

# Search the system for an X*.hosts file, where "*" is a display number
# used to limit X window connections. If no files are found, X*.hosts files
# are not being used. If the X*.hosts files contain any unauthorized hosts,
# this is a finding.

# If both xauth and X*.hosts files are not being used, this is a finding.
#
# Fix Text:
#
# Create an X*.hosts file, where "*" is a display number used to limit X
# window connections. Add the list of authorized X clients to the file.
#######################DISA INFORMATION##################################

# Global Variables
PDI=GEN005220

# Start-Lockdown

redpajama_set_name: RedPajamaGithub


Opracowanie zawiera syntetyczną informację o stanie badań dotyczących rozwoju magnetycznych nieniszczących metod diagnozowania materiałów poddanych działaniu promieniowania neutronowego. We wstępie podane zostały podstawowe informacje o skutkach napromieniowania stali oraz o próbie Charpy'ego. Opisano cztery metody magnetycznego badania próbek stosowanych do testów Charpy'ego: metodę pomiaru kolejnych pętli histerezy, metodę adaptacyjnego doboru warunków magnesowania, metodę pomiaru efektu Barkhausena oraz metodę jednoczesnego badania kilku wielkości magnetycznych. Dla każdej metody podano przykład jej zastosowania.
Paper provides synthetic information about actual state of works on magnetic nondestructive methods proposed for evaluation of microstructure state of steels irradiated with neutrons. Introduction contains basic information about impact of neutrons on steel microstructure and about the Charpy's test.Than four following methods are presented: minor loops metod, magnetic adaptive test metod (mAT), Barkhausen effect method and micro- magnetic – multiparameter – microstructure – Analysis (3MA) method.
Tipping P.G.: Understanding and mitigating aging in nuclear power plants. Woodhead Publishing, 2010.
Wojas M.: Badania nieniszczące w energetyce jądrowej. 40 KKBn, Warszawa, 20011, R01.
Diagnostyka materiałów i Urządzeń Technicznych, 4 Konferencja naukowo-Techniczna, Politechnika Gdańska, 2012, CD ISBN 93-919502-7-1.
Odette G.R., Lucas G.E.: Embrittlement of nuclear reactor pressure vessels, JOm, 53 (7) (2001), 18-22.
Hernandez-mayoral m., Caturla m.J.: microstructure evaluation of irradiated structural materials in nuclear power plants, w , 189-235.
Kobayashi S., Takahashi S.: Current understanding of magnetic property changes in neutron irradiated nRPV steels, UnmnDE meeting, Tatranské matliare, Slovakia, 4-5 IX, 2012.
Dobmann G., Altpeter I., Kopp m.: nondestructive materials Characterization of Irradiated nuclear Pressure-Vessel Steel Samples by the Use of micromagnetic Techniques and in Terms of mechanical properties; Russian Journal of nonde- structive Testing, 42 (2006) 272-277.
Kobayashi S., Gillemot F., Horvath A., Szekely R.: magnetic properties of a highly neutron-irradiated nuclear reactor pressure vessel steel, J. nucl. mater. 421 (2012), 112-116.
Tomáš I., Vértesy G., Gillemot F., Székely R.: nondestructive magnetic Adaptive Testing of nuclear Reactor Pressure Vessel Steel Degradation, J. nuclear materials, (2012), zaakceptowany do druku.
Tomáš I., Vértesy G.: magnetic Adaptive Testing, w nondestructive Testing methods and new Applications, http://www. intechopen.com/articles/show/title/magnetic-adaptive-testing.
Barroso S.P., Horváth m.F., m., Horváth Á., Richard S., Gillemot F.: Correlation among mechanical and physical properties for assessment of radiation damage on nuclear reactor materials; magnetic measurements'12, Tatranské matliare, Slovakia, 2012.
Tomáš I., Vértesy G.: Comparison of different nondestructive magnetic measurement, performed on irradiated reactor steel samples; UnmnDE meeting, Tatranské matliare, Slovakia, 4-5 IX, 2012.
Dobmann G.: Non-Destructive Testing for Ageing management of nuclear Power Components, w: nuclear Power – Control, Reliability and Human Factors, P. Tsvetkov, In- Tech (2011), http://www.intechopen.com/articles/show/title/ non-destructivetesting for ageing management of nuclear power components.


We survey the research on the effect of employment laws in developing countries, using papers published since 2004. The survey is further supported by cross-country correlation analyses. Both exercises show that developing countries with rigid employment laws tend to have larger informal sectors and higher unemployment, especially among young workers. A number of countries, especially in Eastern Europe and West Africa, have recently undergone significant reforms to make employment laws more flexible. Conversely, several countries in Latin America have made employment laws more rigid. These reforms are larger in magnitude than any reforms in developed countries and their study can produce new insights on the benefits of labor regulation. Journal of Comparative Economics 37 (1) (2009) 3-13.
Djankov, Simeon & Ramalho, Rita, 2009. "Employment laws in developing countries," Journal of Comparative Economics, Elsevier, vol. 37(1), pages 3-13, March.
Djankov, Simeon & Ramalho, Rita, 2008. "Employment Laws in Developing Countries," CEPR Discussion Papers 7097, C.E.P.R. Discussion Papers.
Carmen Pagés & Claudio E. Montenegro, 1999. "Job Security and the Age-Composition of Employment: Evidence from Chile," IDB Publications (Working Papers) 1093, Inter-American Development Bank.
Guillermo Mondino & Silvia Montoya, 2004. "The Effects of Labor Market Regulations on Employment Decisions by Firms. Empirical Evidence for Argentina," NBER Chapters,in: Law and Employment: Lessons from Latin America and the Caribbean, pages 351-400 National Bureau of Economic Research, Inc.
Caballero, Ricardo J. & Cowan, Kevin N. & Engel, Eduardo M.R.A. & Micco, Alejandro, 2013. "Effective labor regulation and microeconomic flexibility," Journal of Development Economics, Elsevier, vol. 101(C), pages 92-104.
Ricardo J. Caballero & Kevin N. Cowan & Eduardo M.R.A. Engel & Alejandro Micco, 2004. "Effective Labor Regulation and Microeconomic Flexibility," NBER Working Papers 10744, National Bureau of Economic Research, Inc.
Ricardo J. Caballero & Kevin N. Cowan & Eduardo M.R.A. Engel & Alejandro Micco, 2004. "Effective Labor Regulation and Microeconomic Flexibility," Cowles Foundation Discussion Papers 1480, Cowles Foundation for Research in Economics, Yale University, revised Jun 2010.
Ricardo J Caballero & Kevin N Cowan & Eduardo M.R.A. Engel & Alejandro Micco, 2007. "Effective Labor Regulation and Microeconomic Flexibility," Levine's Bibliography 321307000000000990, UCLA Department of Economics.
Caballero, Ricardo J. & Cowan, Devin N. & Engel, Eduardo M.R.A. & Micco, Alejandro, 2004. "Effective Labor Regulation and Microeconomic Flexibility," Center Discussion Papers 28486, Yale University, Economic Growth Center.
Ricardo J. Caballero & Kevin Cowan & Eduardo M. R. A. Engel & Alejandro Micco, 2004. "Effective labor regulation and microeconomic flexibility," Working Papers 04-6, Federal Reserve Bank of Boston.
Ricardo J. Caballero & Eduardo M.R.A. Engel & Alejandro Micco, 2004. "Effective Labor Regulation and Microeconomic Flexibility," Working Papers 893, Economic Growth Center, Yale University.
Rana Hasan & Devashish Mitra & K.V. Ramaswamy, 2007. "Trade Reforms, Labor Regulations, and Labor-Demand Elasticities: Empirical Evidence from India," The Review of Economics and Statistics, MIT Press, vol. 89(3), pages 466-481, August.
Rana Hasan & Devashish Mitra & K.V. Ramaswamy, 2003. "Trade Reforms, Labor Regulations and Labor-Demand Elasticities: Empirical Evidence from India," NBER Working Papers 9879, National Bureau of Economic Research, Inc.
Rana Hasan & Devashish Mitra & K.V. Ramaswamy, 2003. "Trade Reforms, Labor Regulations and Labor-Demand Elasticities: Empirical Evidence from India," Economics Study Area Working Papers 59, East-West Center, Economics Study Area.
Bibhas Saha, 2006. "Labour Institutions in China and India," Journal of South Asian Development, , vol. 1(2), pages 179-205, October.
Eslava, Marcela & Haltiwanger, John & Kugler, Adriana & Kugler, Maurice, 2004. "The effects of structural reforms on productivity and profitability enhancing reallocation: evidence from Colombia," Journal of Development Economics, Elsevier, vol. 75(2), pages 333-371, December.
Marcela Eslava & John Haltiwanger & Adriana Kugler & Maurice Kugler, 2004. "The Effect of Structural Reforms on Productivity and Profitability Enhancing Reallocation: Evidence from Colombia," NBER Working Papers 10367, National Bureau of Economic Research, Inc.
Eslava, Marcela & Haltiwanger, John & Kugler, Adriana & Kugler, Maurice, 2004. "The effects of structural reforms on productivity and profitabality enhancing reallocation: evidence from Colombia," Discussion Paper Series In Economics And Econometrics 408, Economics Division, School of Social Sciences, University of Southampton.
Marcela Eslava & John Haltiwanger & Adriana Kugler & Maurice Kugler, 2004. "The effects of structural reforms on productivity and profitability enhancing reallocation: Evidence from Colombia," Economics Working Papers 763, Department of Economics and Business, Universitat Pompeu Fabra.
Marcela Eslava & John Haltiwanger & Adriana Kugler & Maurice Kugler, 2004. "The Effects of Structural Reforms on Productivity and Profitability Enhancing Reallocation: Evidence from Colombia," Working Papers 134, Barcelona Graduate School of Economics.
Eslava, Marcela & Haltiwanger Jr, John C & Kugler, Adriana D. & Kugler, Maurice, 2004. "The Effects of Structural Reforms on Productivity- and Profitability-Enhancing Reallocation: Evidence from Colombia," CEPR Discussion Papers 4569, C.E.P.R. Discussion Papers.
James J. Heckman & Carmen Pagés, 2004. "Law and Employment: Lessons from Latin America and the Caribbean," NBER Books, National Bureau of Economic Research, Inc, number heck04-1.
Aditya Bhattacharjea, 2006. "Labour Market Regulation and Industrial Performance in India--A Critical Review of the Empirical Evidence," Working papers 141, Centre for Development Economics, Delhi School of Economics.
Andrew Downes & Nlandu Mamingi & Rose-Marie Belle Antoine, 2004. "Labor Market Regulation and Employment in the Caribbean," NBER Chapters,in: Law and Employment: Lessons from Latin America and the Caribbean, pages 517-552 National Bureau of Economic Research, Inc.
Andrew S. Downes & Nlandu Mamingi & Rose-Marie Belle Antoine, 2000. "Labor Market Regulation and Employment in the Caribbean," Research Department Publications 3088, Inter-American Development Bank, Research Department.
Alejandro Cuñat & Marc J. Melitz, 2012. "Volatility, Labor Market Flexibility, And The Pattern Of Comparative Advantage," Journal of the European Economic Association, European Economic Association, vol. 10(2), pages 225-254, April.
Alejandro Cuñat & Marc J. Melitz, 2007. "Volatility, Labor Market Flexibility, and the Pattern of Comparative Advantage," NBER Working Papers 13062, National Bureau of Economic Research, Inc.
Cuñat, Alejandro & Melitz, Marc J, 2007. "Volatility, Labour Market Flexibility, and the Pattern of Comparative Advantage," CEPR Discussion Papers 6297, C.E.P.R. Discussion Papers.
Cunat, Alejandro & Melitz, Marc J., 2007. "Volatility, labor market flexibility, and the pattern of comparative advantage," LSE Research Online Documents on Economics 19714, London School of Economics and Political Science, LSE Library.
Alejandro Cuñat & Marc J. Melitz, 2007. "Volatility, Labor Market Flexibility, and the Pattern of Comparative Advantage," CEP Discussion Papers dp0799, Centre for Economic Performance, LSE.
Cuñat, Alejandro & Melitz, Marc J., 2012. "Volatility, Labor Market Flexibility, and the Pattern of Comparative Advantage," Scholarly Articles 10914283, Harvard University Department of Economics.
Djankov, Simeon & McLiesh, Caralee & Shleifer, Andrei, 2007. "Private credit in 129 countries," Journal of Financial Economics, Elsevier, vol. 84(2), pages 299-329, May.
Simeon Djankov & Caralee McLiesh & Andrei Shleifer, 2005. "Private Credit in 129 Countries," NBER Working Papers 11078, National Bureau of Economic Research, Inc.
Shleifer, Andrei & Djankov, Simeon & McLiesh, Caralee, 2007. "Private credit in 129 countries?," Scholarly Articles 27867134, Harvard University Department of Economics.
Kugler, Adriana & Kugler, Maurice, 2003. "The Labor Market Effects of Payroll Taxes in a Middle-Income Country: Evidence from Colombia," IZA Discussion Papers 852, Institute for the Study of Labor (IZA).
Kugler, Adriana D. & Kugler, Maurice, 2003. "The Labour Market Effects of Payroll Taxes in a Middle-Income Country: Evidence from Colombia," CEPR Discussion Papers 4046, C.E.P.R. Discussion Papers.
Adriana Kugler & Maurice Kugler, 2003. "The labor market effects of payroll taxes in a middle-income country: Evidence from Colombia," Economics Working Papers 721, Department of Economics and Business, Universitat Pompeu Fabra.
William Kerr & Adriana Kugler & David Autor, 2007. "Do Employment Protections Reduce Productivity? Evidence from U.S. States," Working Papers 07-04, Center for Economic Studies, U.S. Census Bureau.
Autor, David & Kerr, William & Kugler, Adriana, 2007. "Do Employment Protections Reduce Productivity? Evidence from U.S. States," IZA Discussion Papers 2571, Institute for the Study of Labor (IZA).
David H. Autor & William R. Kerr & Adriana D. Kugler, 2007. "Do Employment Protections Reduce Productivity? Evidence from U.S. States," NBER Working Papers 12860, National Bureau of Economic Research, Inc.
David H. Autor & William R. Kerr & Adriana D. Kugler, 2007. "Do Employment Protections Reduce Productivity? Evidence from U.S. States," Harvard Business School Working Papers 07-048, Harvard Business School.
Pedro Portugal & Olivier Blanchard, 2001. "What Hides Behind an Unemployment Rate: Comparing Portuguese and U.S. Labor Markets," American Economic Review, American Economic Association, vol. 91(1), pages 187-207, March.
Kugler, Adriana & Kugler, Maurice, 2003. "The labor market effects of payroll taxes in a middle-income country: evidence from Colombia," Discussion Paper Series In Economics And Econometrics 306, Economics Division, School of Social Sciences, University of Southampton.
Antonio Ciccone & Elias Papaioannou, 2007. "Red Tape and Delayed Entry," Journal of the European Economic Association, MIT Press, vol. 5(2-3), pages 444-458, 04-05.
Ciccone, Antonio & Papaioannou, Elias, 2006. "Red Tape and Delayed Entry," CEPR Discussion Papers 5996, C.E.P.R. Discussion Papers.
Antonio Ciccone & Elias Papaioannou, 2006. "Red tape and delayed entry," Economics Working Papers 985, Department of Economics and Business, Universitat Pompeu Fabra.
Papaioannou, Elias & Ciccone, Antonio, 2007. "Red tape and delayed entry," Working Paper Series 758, European Central Bank.
Jaime Saavedra & Mhmo Torero, 2004. "Labor Market Reforms and Their Impact over Formal Labor Demand and Job Market Turnover. The Case of Peru," NBER Chapters,in: Law and Employment: Lessons from Latin America and the Caribbean, pages 131-182 National Bureau of Economic Research, Inc.
André Stel & David Storey & A. Thurik, 2007. "The Effect of Business Regulations on Nascent and Young Business Entrepreneurship," Small Business Economics, Springer, vol. 28(2), pages 171-186, March.
van Stel, A.J. & Storey, D. & Thurik, A.R., 2006. "The Effect of Business Regulations on Nascent and Young Business Entrepreneurship," ERIM Report Series Research in Management ERS-2006-052-ORG, Erasmus Research Institute of Management (ERIM), ERIM is the joint research institute of the Rotterdam School of Management, Erasmus University and the Erasmus School of Economics (ESE) at Erasmus University Rotterdam.
André van Stel & Roy Thurik & David Storey, 2006. "The effect of business regulations on nascent and young business entrepreneurship," Scales Research Reports H200609, EIM Business and Policy Research.
Sanyal, Paroma & Menon, Nidhiya, 2005. "Labor Disputes and the Economics of Firm Geography: A Study of Domestic Investment in India," Economic Development and Cultural Change, University of Chicago Press, vol. 53(4), pages 825-854, July.
Ricardo Paes de Barros & Carlos Henrique Corseuil, 2004. "The Impact of Regulations on Brazilian Labor Market Performance," NBER Chapters,in: Law and Employment: Lessons from Latin America and the Caribbean, pages 273-350 National Bureau of Economic Research, Inc.
Ricardo Paes de Barros & Carlos Henrique Corseuil, 2001. "The Impact of Regulations on Brazilian Labor Market Performance," Research Department Publications 3124, Inter-American Development Bank, Research Department.
Kugler, Adriana & Kugler, Maurice, 2003. "The labor market effects of payroll taxes in a middle-income country: evidence from Colombia," Discussion Paper Series In Economics And Econometrics 0306, Economics Division, School of Social Sciences, University of Southampton.
Claudio Montenegro & Carmen Pagés, 2005. "Who Benefits from Labor Market Regulations? Chile 1960-1998," Central Banking, Analysis, and Economic Policies Book Series,in: Jorge Restrepo & Andrea Tokman R. & Norman Loayza (Series Editor) & Klaus Schmidt-Hebbel (Series Edi (ed.), Labor Markets and Institutions, edition 1, volume 8, chapter 4, pages 077-114 Central Bank of Chile.
Claudio E. Montenegro & Carmen Pagés, 2004. "Who Benefits from Labor Market Regulations? Chile, 1960-1998," NBER Chapters,in: Law and Employment: Lessons from Latin America and the Caribbean, pages 401-434 National Bureau of Economic Research, Inc.
Safavian, Mehnaz & Sharma, Siddharth, 2007. "When do creditor rights work?," Journal of Comparative Economics, Elsevier, vol. 35(3), pages 484-508, September.
Feldmann, Horst, 2009. "The unemployment effects of labor regulation around the world," Journal of Comparative Economics, Elsevier, vol. 37(1), pages 76-90, March.
Dutta Roy, Sudipta, 2004. "Employment dynamics in Indian industry: adjustment lags and the impact of job security regulations," Journal of Development Economics, Elsevier, vol. 73(1), pages 233-256, February.
Ahsan, Ahmad & Pagés, Carmen, 2009. "Are all labor regulations equal? Evidence from Indian manufacturing," Journal of Comparative Economics, Elsevier, vol. 37(1), pages 62-75, March.
Ahsan, Ahmad & Pagés, Carmen, 2008. "Are All Labor Regulations Equal? Evidence from Indian Manufacturing," IZA Discussion Papers 3394, Institute for the Study of Labor (IZA).
Velenchik, Ann D., 1997. "Market power, firm performance and real wage growth in Zimbabwean manufacturing," World Development, Elsevier, vol. 25(5), pages 749-762, May.
Silvia Ardagna & Annamaria Lusardi, 2010. "Explaining International Differences in Entrepreneurship: The Role of Individual Characteristics and Regulatory Constraints," NBER Chapters,in: International Differences in Entrepreneurship, pages 17-62 National Bureau of Economic Research, Inc.
Silvia Ardagna & Annamaria Lusardi, 2008. "Explaining International Differences in Entrepreneurship: The Role of Individual Characteristics and Regulatory Constraints," NBER Working Papers 14012, National Bureau of Economic Research, Inc.
Kaplan, David S., 2009. "Job creation and labor reform in Latin America," Journal of Comparative Economics, Elsevier, vol. 37(1), pages 91-105, March.
Kaplan, David S., 2008. "Job creation and labor reform in Latin America," Policy Research Working Paper Series 4708, The World Bank.
Adriana Kugler adkugler@uh.edu & Giovanni Pica, 2005. "The Effects of Employment Protection on the Italian Labour Market," CSEF Working Papers 135, Centre for Studies in Economics and Finance (CSEF), University of Naples, Italy.
Horst Feldmann, 2008. "Business regulation and labor market performance around the world," Journal of Regulatory Economics, Springer, vol. 33(2), pages 201-235, April.
Freund, Caroline & Bolaky, Bineswaree, 2008. "Trade, regulations, and income," Journal of Development Economics, Elsevier, vol. 87(2), pages 309-321, October.
Safavian, Mehnaz & Sharma, Siddharth, 2007. "When do creditor rights work?," Policy Research Working Paper Series 4296, The World Bank.
Carmen Pagés & Claudio E. Montenegro, 2007. "Job security and the age-composition of employment: evidence from Chile," Estudios de Economia, University of Chile, Department of Economics, vol. 34(2 Year 20), pages 109-139, December.
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:eee:jcecon:v:37:y:2009:i:1:p:3-13. See general information about how to correct material in RePEc.


text:
Shopping Cart Register
Verfication Code: *
Patent Journals
Free Online Samples
Journals Impacting Science
New Title 2019
Price and Ordering Information
Subscription Rates 2019
By Video Ebooks
Forthcoming Series
Future Attraction
Future Titles
Future Series
Articles By Disease
Bentham Online
Bentham Insight
Purchase Articles
Journal and eBook Catalog
Author's Benefits Guide
Events By Subject Areas
Drug Design, Discovery and Therapy
Energy and Fuels
Food Sciences and Nutrition
Technology Transfer and Entrepreneurship
Health Care Industry Resources
Parterning Events
Promotional Services
FAQs for e-prints/reprints
Journal Catalog 2019
Order Bulk Reprints
Order Bulk ePrints
Library Recommendation
Table of Content Alerts
Trial Requests
For Authors & Editors
Online Journal Management System
Author Benefits
Editor Policies
Publication Cycle - Process Flowchart
Self-Archiving Policies
Ordering & Subscription
One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents
Author(s): Fathy M. Abdelrazek, Chemistry Department, Faculty of Science, Cairo University, Cairo 12613, Egypt	Sobhi M. Gomha*, Chemistry Department, Faculty of Science, Cairo University, Cairo 12613, Egypt	Mohamed E.B. Shaaban, Chemistry Department, Faculty of Science, Ain-Shams University, Egypt	Kamal A. Rabee, Nuclear Material Authority, Kattameya, Egypt	Heba N. El-Shemy, Chemistry Department, Faculty of Science, Ain-Shams University, Egypt	Abanoub M. Abdallah, Narcotic Research Department, National Center for Social and Criminological Research, Giza 11561, Egypt	Peter Metz. Institute of Organic Chemistry, TU-Dresden, Dresden 01062, Germany
Journal Name: Mini-Reviews in Medicinal Chemistry
Volume 19 , Issue 6 , 2019
DOI : 10.2174/1389557518666181019124104
Graphical Abstract:
Background: Thiazoles and pyridines are versatile synthetic scaffolds possessing wide spectrum of biological effects including potential antimicrobial activity.
Objective: In the efforts to develop suitable antimicrobia drugs, medicinal chemists have focused on thiazole derivatives. A novel series of 2-thiazolyl pyridines was prepared in a one-pot three-component reaction using 2-bromoacetyl pyridine as a starting precursor.
Method: Structure of the synthesized compounds was elucidated by spectral data (FT-IR, 1H NMR, 13C NMR, and mass) and elemental analyses. The prepared compounds were screened for their in vitro antimicrobial activity.
Results: The results revealed that compounds 4a,b,e-g and 12 showed promising activity. Molecular docking studies using MOE software were carried out for compounds 4a and 4b which exhibited potent activities indicated by the diameter zones (4a; 3.6, 4.0, 1.2 mm) (4b; 4.2, 3.5, 1.5 mm) and the binding affinities (4a; -5.7731, -5.3576, -4.6844 kcal mol-1) (4b; -5.9356, -2.8250, -5.3628 kcal mol-1) against Candida albicans, Bacillus subtilis and Escherichia coli, respectively.
Conclusion: This paper describes a facile and efficient MCR for synthesis of 2-thiazolyl pyridines from reaction of 2-bromoacetyl pyridine with different reagents. There was an agreement between the values of binding affinities and interactions and the data obtained from the practical antimicrobial screening of the tested compounds.
Keywords: 2-Bromoacetylpyridine, thiosemicarbazide, thiazoles, hydrazonoyl halides, antimicrobial activity, molecular docking studies.
Karegoudar, P.; Karthikeyan, M.S.; Prasad, D.J.; Mahalinga, M.; Holla, B.S.; Kumari, N.S. Synthesis of some novel 2,4-disubstituted thiazoles as possible antimicrobial agents. Eur. J. Med. Chem., 2008, 43, 261-267.
Cukurovali, A.; Yilmaz, I.; Gur, S.; Kazaz, C. Synthesis, antibacterial and antifungal activity of some new thiazolylhydrazone derivatives containing 3-substituted cyclobutane ring. Eur. J. Med. Chem., 2006, 41, 201-207.
Abdel-Wahab, B.F.; Abdel-Aziz, H.A.; Ahmed, E.M. Synthesis and antimicrobial evaluation of 1-(benzofuran-2-yl)-4-nitro-3-arylbutan-1-ones and 3-(benzofuran-2-yl)-4,5-dihydro- 5-aryl- 1-[4-(aryl)-1,3-thiazol-2-yl]-1H-pyrazoles. Eur. J. Med. Chem., 2009, 44, 2632-2635.
Shih, M.H.; Ying, K.F. Syntheses and evaluation of antioxidant activity of sydnonyl substituted thiazolidinone and thiazoline derivatives. Bioorg. Med. Chem., 2004, 12, 4633-4643.
Shiradkar, M.; Kumar, G.V.S.; Dasari, V.; Tatikonda, S.; Akula, K.C.; Shah, R. Clubbed triazoles: a novel approach to antitubercular drugs. Eur. J. Med. Chem., 2007, 42(6), 807-816.
Amin, K.M.; Rahman, A.D.E.; Al-Eryani, Y.A. Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents. Bioorg. Med. Chem., 2008, 16, 5377-5388.
Gomha, S.M.; Riyadh, S.M.; Abbas, I.M.; Bauomi, M.A. Synthetic utility of ethylidenethiosemicarbazide: synthesis and anticancer activity of 1,3-thiazines and thiazoles with imidazole moiety. Heterocycles, 2013, 87, 341-356.
Gomha, S.M.; Abdel-aziz, H.M.; Khalil, K.D. Synthesis and SAR study of the novel thiadiazole-imidazole derivatives as new anti-cancer agents. Chem. Pharm. Bull., 2016, 64, 1356-1363.
Gomha, S.M.; Edrees, M.M.; Altalbawy, F.M.A. Synthesis and characterization of some new bis-pyrazolyl-thiazoles incorporating the thiophene moiety as potent anti-tumor agents. Intl. J. Mol. Sci.,2016, 17, 1499(1-12).
Gomha, S.M.; Salah, T.A.; Abdelhamid, A.O. Synthesis, characterization and pharmaco- logical evaluation of some novel thiadiazoles and thiazoles incorporating pyrazole moiety as potent anticancer agents. Monatsh. Chem., 2015, 146, 149-158.
Abdalla, M.A.; Gomha, S.M.; Abdelaziz, M.; Serag, N. Synthesis and antiviral evaluation of some novel thiazoles and 1,3-thiazines substituted with pyrazole moiety against rabies virus. Turk. J. Chem., 2016, 40, 441-453.
Dawood, K.M.; Gawad, H.A.; Rageb, E.A.; Ellithey, M.; Mohamed, H.A. Synthesis, anticonvulsant, anti-inflammatory evaluation of some new benzotriazole and bezofuran-based heterocycle. Bioorg. Med. Chem., 2006, 14, 3672-3680.
Carter, J.S.; Kramer, S.; Talley, J.J.; Penning, T.; Collins, P.; Graneto, M.J.; Seibert, K.; Koboldt, C.; Masferrer, J.; Zweifel, B. Synthesis and activity of sulfonamide-substituted 4,5-diaryl thiazoles as selective cyclooxygenase-2 inhibitors. Bioorg. Med. Chem. Lett., 1999, 9, 1171-1174.
Zhu, L.P.; Ye, D.Y.; Tang, Y. Structure-based 3D-QSAR studies on thiazoles as 5-HT3 receptor antagonists. J. Mol. Model., 2007, 13, 121-131.
Clark, R.F.; Zhang, T.; Wang, X.; Wang, R.; Zhang, X.; Camp, H.S.; Beutel, B.A.; Sham, H.L.; Gu, Y.J. Phenoxy thiazole derivatives as potent and selective acetyl-CoA carboxylase 2 inhibitors: Modulation of isozyme selectivity by incorporation of phenyl ring substituents. Bioorg. Med. Chem. Lett., 2007, 17, 1961-1965.
Saravanan, G.; Alagarsamy, V.; Prakash, C.R.; Kumar, P.; Dinesh, T.; Selvam, P. Synthesis of novel thiazole derivatives as analgesic agents. Asian J. Res. Pharm. Sci., 2011, 1, 134-138.
Abdelrazek, F.M.; Metz, P.; Metwally, N.H.; El-Mahrouky, S.F. Synthesis and molluscicidal activity of new cinnoline and pyrano [2,3-c]pyrazole Derivatives. Arch. Pharm. Chem. life Sci.,2006, 339, 456-460.
Abdelrazek, F.M.; Metwally, N.H. Novel synthesis of N-arylpyrrole, pyrrolo[1,2-a] quinazoline, and pyrrolo[3,4-d]pyridazine derivatives. Synth. Commun., 2009, 39, 4088-4099.
Abdelrazek, F.M.; Kassab, N.A.; Metwally, N.H.; Sobhy, N.A. Synthesis of some novel pyridine and naphthyridine derivatives. Eur. J. Chem., 2010, 1, 368-372.
Gomha, S.M.; Abdelrazek, F.M.; Abdulla, M.M.J. Synthesis of new functionalised derivatives of [1,2,4]triazolo[4,3-a]pyrimidine and pyrimido[2,1-b][1,3,5]thiadiazine as aromatase inhibitors. Chem. Res., 2015, 39, 425-429.
Gomha, S.M.; Eldebss, T.M.A.; Abdulla, M.M.; Mayhoub, A.S. Diphenylpyrroles: Novel p53 activators. Eur. J. Med. Chem., 2014, 82, 472-479.
Gomha, S.M. A facile one-pot synthesis of 6,7,8,9-tetrahydrobenzo[4,5]thieno[2,3-d]- 1,2,4-triazolo[4,5-a]pyrimidin-5-ones. Monatsh. Chem., 2009, 140, 213-220.
Badrey, M.G.; Gomha, S.M. 3-Amino-8-hydroxy-4-imino-6-methyl-5-phenyl-4,5–dihydro -3H-chromeno[2,3-d]pyrimidine: An Effecient key precursor for novel synthesis of some interesting triazines and triazepines as potential anti-tumor agents. Molecules, 2012, 17, 11538-11553.
Abbas, I.M.; Gomha, S.M.; Elneairy, M.A.A.; Elaasser, M.M.; Mabrouk, B.K.A. Synthesis and characterisation of some novel fused thiazolo[3,2-a]pyrimidinones and pyrimido[2,1-b][1,3]-thiazinones. J. Chem. Res., 2015, 39, 719-723.
Abdelrazek, F.M.; Gomha, S.M.; Abdelrahman, A.H.; Metz, P.; Sayed, M.A. A Facile synthesis and drug design of some new heterocyclic compounds incorporating pyridine moiety and their antimicrobial evaluation; Lett. Drug Des. Disc, 2017.
Abdelrazek, F.M.; Gomha, S.M.; Metz, P.; Abdulla, M.M. Synthesis of some novel 1,4-phenylene-bis-thiazolyl derivatives and their anti-hypertensive α-blocking activity screening. J. Heterocycl. Chem., 2017, 54, 618-623.
Gomha, S.M.; Abdelrazek, F.M.; Abdelrahman, A.H.; Metz, P. Synthesis of some novel thiazole, thiadiazole and 1,4-phenelen-bis-thiazole derivatives as potent antitumor agent. Heterocycles, 2016, 92, 954-967.
Hossain, M.A.; Shah, M.D.; Sang, S.V.; Sakari, M. Chemical composition and antibacterial properties of the essential oil and crude extract of merremia borneesis. J. King Saud. Univ., 2012, 24, 243-249.
Molecular operating environment (MOE 2008.10), Chemical computing group inc., montreal, QC, Canada.
RCSB Protein Data Bank. http://www.rcsb.org/
Mjambili, F.; Njoroge, M.; Naran, K.; De Kock, C.; Smith, P.J.; Mizrahi, V.; Warner, D.; Chibale, K. Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents. Bioorg. Med. Chem. Lett., 2014, 24, 560-564.
Mohammad, S.A.; Lijun, L.; Eok, L.Y.; Ung, L.D. Synthesis, Antibacterial Activity and Quantum-Chemical Studies of Novel
2-Arylidenehydrazinyl-4-arylthiazole Analogues. Chem. Pharm. Bull., 2011, 59, 568-573.
Shawali, A.S.; Gomha, S.M. A New Entry for Short and regioselective synthesis of [1,2,4]triazolo[4,3-b][1,2,4]-triazin-7(1H)-ones. Adv. Synth. Catal., 2000, 342, 599-604.
Rights & PermissionsPrintExport Cite as
Mini-Reviews in Medicinal Chemistry
Title:One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents
VOLUME: 19	ISSUE: 6
Author(s):Fathy M. Abdelrazek, Sobhi M. Gomha*, Mohamed E.B. Shaaban, Kamal A. Rabee, Heba N. El-Shemy, Abanoub M. Abdallah and Peter Metz
Affiliation:Chemistry Department, Faculty of Science, Cairo University, Cairo 12613, Chemistry Department, Faculty of Science, Cairo University, Cairo 12613, Chemistry Department, Faculty of Science, Ain-Shams University, Nuclear Material Authority, Kattameya, Chemistry Department, Faculty of Science, Ain-Shams University, Narcotic Research Department, National Center for Social and Criminological Research, Giza 11561, Institute of Organic Chemistry, TU-Dresden, Dresden 01062
Keywords:2-Bromoacetylpyridine, thiosemicarbazide, thiazoles, hydrazonoyl halides, antimicrobial activity, molecular docking studies.
Abstract:Background: Thiazoles and pyridines are versatile synthetic scaffolds possessing wide spectrum of biological effects including potential antimicrobial activity.
Export File:
RIS (for EndNote, Reference Manager, ProCite)
Fathy M. Abdelrazek, Sobhi M. Gomha*, Mohamed E.B. Shaaban, Kamal A. Rabee, Heba N. El-Shemy, Abanoub M. Abdallah and Peter Metz, "One-Pot Three-Component Synthesis and Molecular Docking of Some Novel 2-Thiazolyl Pyridines as Potent Antimicrobial Agents", Mini-Reviews in Medicinal Chemistry (2019) 19: 527. https://doi.org/10.2174/1389557518666181019124104
https://doi.org/10.2174/1389557518666181019124104 Print ISSN
Bentham Science Publisher Online ISSN
Page: [527 - 538]
DOI: 10.2174/1389557518666181019124104
PDF: 23
HTML: 2
Journal Insight
Best viewed in © 2019 Bentham Science Publishers


We have several different interactive maps available to the public. Click on the thumbnail to use the associated viewer!
Created with the help of Allegany State Park staff, our Allegany State Park Flex Viewer contains all of the campsites, cabin trails and cottages that are available for rent and are complete with street level photography for each site. Aerial and oblique photography of campsites and cabins can be viewed with the Pictometry widget to gain a better perspective on the site/area of interest. When a site of interest has been found, each cabin/campsite point contains a link to the ASP reservation page so the site can be reserved. Also present on the viewer are hiking trails complete with photos and other points of interest within the park.
For information on how to view and save this viewer on an Android device, click here.
For information on how to view and save this viewer on an iPhone or iPad, click here.
Our Cemetery Viewer contains information from several cemeteries within Cattaraugus County. Each headstone has been accurately placed on the map with the use of a high powered GPS unit, along with its given information if readable. Photos have been taken of each headstone and are displayed on the viewer as well. There is also a search widget on the viewer, where headstones can be searched by cemetery, occupant last name and death date.
Our County Trails Flex Viewer shows all of the different trails within the county and several of those that are outside the county. Such trails include snowmobile trails, hiking, biking, and horse trails. The elevation profile tool can be used to find differences in elevations along trail sections, or along entire trails.
NOTE: Above interactive map is not compatible with mobile technology.
Our Outdoor Viewer contains the same parcel information that is available on our Parcel Viewer, along with information on state lands, state land parking areas, public fishing access and areas of public fishing rights, and stores with hunting and fishing supplies. Environmental information such as contours, lake contours and water bodies are also available. The application has the ability to make use of GPS capabilities within mobile devices, which will pinpoint your location on the map.
Our Snowmobile Viewer contains all of the funded and some of the unfunded trails within Cattaraugus County, restaurants, repair shops, gas stations and lodging locations that are pertinent to snowmobilers. All of which can be accessed on a smart phone that can find your GPS location!
More interactive maps available soon!


Mikhail is leading Natural Resources Sector in IBM EE/A responsible for industry strategy, solutions, offerings, alliances, centre of excellence, eminence and senior talent for the Natural Resource team serving our major clients and key geographies across all IBM lines of business. He is a senior business leader with significant industry strategy, business development, client service and people leadership experience across business consulting and broad range of IT solutions from plant floor automation to ERP and analytics.
Mikhail has over 20 years of experience with a track record of large scale and first of a kind business and technology transformations for clients with a primary focus on enterprise resource planning, asset management, budgeting, MES and plant floor process automation. Mikhail's current focus is helping clients achieve improved business performance through Digital Reinvention including iX, Cognitive & Analytics, Internet of Things, Blockchain and As a Service transformation. From 2011 till 2016 Mikhail was Associate Partner in IBM Global Business Services leading consulting and integration projects primarily in Metal and Mining and Oil&Gas industries.


The center of an escutcheon.
1. a bottomless or unfathomed depth, gulf, or chasm; hence, any deep, immeasurable, and, specifically, hell, or the bottomless pit. ye powers and spirits of this nethermost abyss. the throne is darkness, in the abyss of light.
2. infinite time; a vast intellectual or moral depth. the abysses of metaphysical theology. in unfathomable abysses of disgrace.
3. (her.) the center of an escutcheon.
note: this word, in its leading uses, is associated with the cosmological notions of the hebrews, having reference to a supposed illimitable mass of waters from which our earth sprung, and beneath whose profound depths the wicked were punished. brit.
For a woman to be looking into an abyss, foretells that she will burden herself with unwelcome cares. If she falls into the abyss her disappointment will be complete; but if she succeeds in crossing, or avoiding it, she will reinstate herself.
That volume of ocean lying below 300 fathoms from surface.
Abyss [from Greek a not + byssos, bythos deep, depth] Bottomless, unfathomable; chaos, space, the watery abyss which becomes the field of manifestation or cosmos -- a concept found in all mythologies. With the Sumerians, Akkadians, and Babylonians the great Deep gave birth to Ea, the All-wise, unknowable infinite deity, while in the Chaldean cosmogony Tiamat, the female principle, is the imbodiment of chaos. The Abyss or chaos was the abode of cosmic wisdom. Egyptian cosmogony speaks of Nut as the celestial abyss while Scandinavian cosmogony tells of Ginnungagap (chasm of offspring of Ginn), the infinite void or the abyss of illusion (SD 1:367).


My family has lived and worked at the beach since 1962 and I am celebrating 40+ years in the real estate industry. I am blessed to have both my daughters and families nearby.
I manage the Windermere Real Estate office in Ocean Shores, WA and specialize in commercial properties and development. My prior commercial development projects have included Seabrook; Best Western, Shilo, & McDonalds (Ocean Shores), plus many more.
I love all aspects of commercial real estate. I am a Certified Commercial Investment Member (CCIM).
CCIM stands for Certified Commercial Investment Member. The CCIM lapel pin denotes that the wearer has completed advanced course work in financial and market analysis, and demonstrated extensive experience in the commercial real estate industry. CCIM designees are recognized as leading experts in commercial investment real estate..


Samama Gulberg StarMarketing Islamabad Embrace the felicitous circumferential where your whims are let loose to flutter and swoop. Open those pearly gates and see the prodigy of the millennia, the Samama estate. Samama builders and developers after successful ventures of building and construction in Karachi are now securing the ground in Islamabad as well named Samama Gulberg StarMarketing Islamabad. The victorious projects in Karachi include Samama Hill view, Samama shopping complex, Samama shopping arena and tower and Samama City to name a few. The rightest site The enormous venture by Samama builders is erected in the serene terrain of Gulberg Islamabad surrounded by wide main roads. Gulberg Islamabad is readily located at the main Islamabad expressway near Airport. The joint undertaking or Gulberg Islamabad and the Samama builders will make the outcome of the next level in the already city of Green. A fine erection The miracle edifice of eight stories is ideal and up to the minute in design, structure and apparatus. The condominium is built in line with ultra modern planning and execution. All the key provisions of a world class residence and a shopping plaza are keenly concentrated. Recreation is inside Samama Gulberg fashions for you an atmosphere which is conducive for your souls to bloom and spring. Being locked in the green contours of Gulberg Islamabad, the apartments offer a dream living in a compact. Here in the living unit, recreation is inside. The Compartmentalization The apartments are squarely categorized in three different settings. The first offering is a studio apartment constructed in modish style. Moreover, there are 2 and 3 bed apartments of 750 and 950 square yards respectively. The rooms are spacious and accommodating with affixed bathrooms and sufficient vents and openings. Each unit consists of a commodious kitchen, a living room, terrace and a store room to accommodate furnishings. A la mode What's in fashion is the question that drives the era. To look for the best solution to feed our bulging desires we need an outlet where all in one is disseminated. The Samama Gulberg eases your exhaustion. The bottom three floors of the apartment are reserved for a shopping galleria. The shopping center secures shops of varying sizes to accommodate a good range of articles of utility. High tech equipage In the age of robotics, a manual setting appears boring and humdrum. The Samama Gulberg is equipped with high tech amenities. There are automated lifts, escalators, electronic surveillance via CCTV cameras and a monitoring unit, standby generators and fire alarms. Secure Gated Security is always the first concern. The boundaries of the proposed enterprise are secure and religiously guarded with CCTV cameras on imperative distances. Manual security personnel are also proposed to assure the safety of the inhabitants to the fullest. Cook the book of Samama Gulberg StarMarketing Islamabad Take a leap and make your decision today. Don't miss out your dream unit in the city of calm. Skim through the cordial booking plans. There are easy installments and stupendous discounts on half and full payment.


100 things to do in 1000 days; #81: Do pottery (make a pot or a vase).
Literally two months to the day after Doing Pottery, I was finally able to pick up the completed pieces (painted and glazed by Paul, in the colours requested by me).
I don't really have anything interesting or funny to say about it. But yay, 47 Things done!


text:
, född 16 april 1986 i Fukuoka prefektur, är en japansk fotbollsspelare.

Jogo började sin karriär 2005 i Avispa Fukuoka.

Källor

Japanska fotbollsspelare
Spelare i Avispa Fukuoka
Födda 1986
Levande personer
Män
Personer från Fukuoka prefektur

redpajama_set_name: RedPajamaWikipedia


text:
NBC Journalists Decide Tom Brokaw's #MeToo to Become #NotHim!
Posted at 12:00 pm on May 1, 2018 by Brad Slager
Tom Brokaw accused of getting "handsy", or "grabby" with female staffers
News broke late last week that once esteemed journalist and national news anchor Tom Brokaw was being accused by a couple of women of the now very familiar charge of workplace sexual harassment. Brokaw was facing his own "Me Too" crisis, but his contemporaries are trying to see that he does not become another statistic, and avoid joining Matt Lauer, Mark Halperin, and other journalists felled by their predatory acts. This is rather amazing.
Journalists love to play referee with our moral standards. Dictating proper behavior and predicating societal comportment are among their favorite pastimes. When it comes to actually following their own rules, or enforcing those protocols among their own contemporaries, there tends to be a blindspot massive enough to require Radial Keratotomy.
This past week our media nannies willfully assailed the character of a Presidential nominee. President Trump's choice to head the Veteran Affairs office, Ronny Jackson, went from being a respected physician over numerous Presidential administrations to a political pariah. When he was nominated to head the VA suddenly a rash of charges welled up about his personal behavior.
The press comfortably repeated many of the charges mentioned in Congressional committee, despite the fact that no tangible evidence was ever presented. Jon Tester (D-MT) had presented a document said to be filled with testimony from anonymous sources, all claiming numerous drunken episodes, and even one incident of drunk driving where a government vehicle was crashed.
The media ran all these stories as verified, but then the Secret Service came out with an announcement that they conducted exhaustive research and could find no records of these incidents taking place. No official reports were ever presented – from the SS nor D.C. police – recording a government vehicle crash. Tester had no response when presented with the SS findings, but the damage was successful. Jackson withdrew himself from consideration. The press had their scalp, and Trump was again smeared with administration foibles.
At almost the same time news of the Brokaw controversy broke, and the press reaction was confounding, contradictory, a paradox. Rather than anonymous sources, named women were willing to go on the record and declare how they were mistreated by Brokaw. Since last October this type of report has torpedoed the careers of numerous offenders. Somehow Brokaw is different.
Instead of being chased off we see the legendary journalist defended. A letter of support was drafted, signed by a lengthy list of female co-workers. As Joe Cunningham showed this morning, some inside NBC offices felt they were compelled by management to sign onto the document.
What I find striking is that some of the prominent names on the list (the letter is available here) such as Rachael Maddow, Andrea Mitchell, Mika Brzezinski and the like, are the same ones who have told us in previous months how important it is to believe these charges. "All women are to be believed", has been the mantra of the #MeToo movement, and yet now that standard does not apply. Why?
Brokaw is not being secretly charged by a female using a pseudonym. Former NBC anchor Linda Vester is the one coming forward, willing to go on the record, on camera, and describe numerous episodes with Brokaw misbehavior. This is as solid of an accusation as we have seen prior, from a respected reporter no less. And it is leading nowhere. The women of NBC are NOT supporting a female colleague/victim?!
Also evading accountability right now is MSNBC's Joy Reid. She has been outed for writing homophobic blog posts from years back. She made the excuse that the archives of her decade-old blog were hacked by an outside source. This claim had been proven false, and other desperate claims by Reid were proven additionally absurd, yet she has not absorbed professional retribution. Normally these anti-homosexual comments would lead to a call for terminations. (Recall, Brendan Eich had to step down as FireFox's CEO when he was dubbed "homophobic" for political donations he made years earlier.)
So when an administration official is presented for a post, rumor and innuendo is enough for the media to report wrongdoing. When journalists however have credible, evidence-backed charges leveled against them they get excused away, and any escape hatch is opened.
It almost appears like the press has a set of rules to be enforced upon others and yet the applicable nature is not extended within its own industry. (Need a term for this.) This of course means their future accusations against others should become neutered, and these contradictions need to be thrown back in their face to show the lack of sincerity in the charges.
When Tom Brokaw is permitted to get away with this behavior, believe me, I'll be sure to demand #MeToo!
for more trenchant analysis, and entertainment views, follow me @MartiniShark
Tags: #MeToo Journalists Joy Reid MSNBC NBC News News Media press ronny jackson Tom Brokaw
Impeachment Truths From Ken Starr
Stu Cvrk
Whoopi Goldberg and Joy Behar: Trump's the Reason 176 Innocents Lost Their Lives
DCCC Chair Cowers in Fear as AOC Plots Against Her Own Party
Busted! Facebook Bug Reveals Greta Thunberg's Posts Are Written by Her Father
Man Tries to Kidnap a 6-Year-Old Girl in California, a U.S. Army Vet Steps in With the Takedown of a Lifetime (Video)
Cocaine Mitch Mic Drops Pelosi, Schiff on Senate Floor: We Were Never Going to Be Dictated to by You (Watch)
Actually Chuck Schumer's Strategy For Winning the Impeachment Trial Sounds Like a Press Release Aimed at the Resistance
45-Year-Old Convicted Sex Offender Protests to the Judge: He Identifies as an 8-Year-Old Girl
The Party of WOKE Decides to CHOKE With Only Old White People Runningf for President
California Is Ripe for a Trump-Style Upset
NBC: Transgender Men Face More Suffering From Their Periods Than Women Do
Bernie and Warren Finally Come to Blows and Things Get Ugly
#Journalism: NBC Reporter Manages to Blame Trump for Ukraine Plane Being Shot Down in Iran, Gets Schooled
'Beloved Hero': Chris Matthews Compares Soleimani to Princess Diana and Elvis
My Remarks At Rotary Executive Speakers Series
'Completely flustered': John Kerry slams Trump tweet about Iran Deal funding terrorism, then is shown what he said in 2016 (hint: AWKWARD)
RI AG Wants Hometown Police Notified Of Gun Purchases
John Kerry Claims Obama 'Never Had a Whiff of Scandal' So Let's Remind Him Of Some


I had a great time during the first weekend of December at Bark & Fitz in Westboro and Kanata doing our Happy Howlidays fundraiser for BARK Rescue.
I want to thank each and every dog and their humans that came out to support this great charity. In our two day event, we were able to raise over $700!
Here are a few favourites from the event. To see all of the photos from the event, click here.


Darrell and Sally are two best friends. They had a large collection of marbles. They devised a game with it to play in their free time which will also help them to improve their math. One of them will have to select a certain number of marbles and give a hint to find the number. The other will have to guess the first number that matches the given criteria and vice versa.
Your task is to act as a judge for this game. When the player finds the answer, you will have to verify the answer. If answer is right, add 10 points to that player. If the player passes the question, you will have to give the right answer (no change in points in this case). You should also announce the winner at the end of the game.
When the marbles are put into a group of x1, x2, x3,...(where x1, x2, x3 can be any number from 1 to 100), it falls into a perfect group.(No marble is left without a group).
answer above can only be an integer number OR it will be a constant string "PASS"
In case of any Invalid Question Posing line, requisite output must be printed for all previous Valid Question posing line(s).
output "Answer is: " where correct_answer_value is the correct answer for the question passed by the player.
If there is a winner Output "Game Result: is winner" or "Game Result: Draw"


The commercial pest control technicians at Top Quality Pest Control of Mission Viejo have experience treating the pest control issues that face commercial properties in the Mission Viejo area.
Our pest control exterminators are educated with the pests that are most common at Mission Viejo commercial buildings. That includes cockroaches, spiders, mice, flies, rats, and wasps.
Protect your brand and your reputation by calling 949-424-2585 for all of your pest needs!
Our Mission Viejo commercial pest control exterminators are continuously learning about the latest techniques for keeping your workers and clients protected from pests and rodents.
From dealing with so many Mission Viejo companies we've come to realize that each business is not alike when it comes to pest infestations. This is why we design a specific treatment to fit your needs.
Our Mission Viejo pest control exterminators will completely examine your building to determine any on going infestations, along with any other areas that could be vulnerable to a pest issue. Then we can generate a pest control plan-of-action that fits the unique characteristics of your facility and challenge.
We will use only the safest, most effective pest treatments in your business's building. Our highly trained Mission Viejo technicians will keep your clientele and workers free from harm during the the process.
Call us now to see what our commercial pest control Mission Viejo technicians can do for your business. Our technicians are available to answer any questions you have, so give us a call at 949-424-2585 today.


ACTIV'INSIDE will give you a unique experience at Vitafoods Europe 2018 (Geneva, 15-17 May). Immersed in the human brain, you will not only see the impact of time and environment on the neuronal network, but also the clinically proven effectiveness of MemophenolTM and its mechanism of action on your memory. Just come and try!
ACTIV'INSIDE will also present you its solutions that meet all your needs. Discover our products from natural plant extracts – especially saffron, grapes but also lemon balm and other raw materials – to innovative active solutions patented and clinically tested. Activ'Inside also offers collaborations in finished products development and private labelling.
Come to see us on booth G55.
"Did you ever wonder how your cognitive system works? How does an active ingredient act on memory?
Stop searching, let's come and see by yourself!".
ACTIV'INSIDE has an innovative active formulation to prevent cognitive decline. This ingredient, called MemophenolTM*, has been demonstrated to significantly improve neurogenesis (formation of new neurons) and promote synaptic plasticity (communication between neurons). At Vitafoods Europe 2018, ACTIV'INSIDE proposes to everyone to put a virtual reality headset and explore – become immersed in – the virtual world of the brain. Let's see MemophenolTM passing through the brain blood barrier and preventing the alterations caused by stress and environmental factors to prevent cognitive decline.
"As a picture is worth a thousand words, this innovative technology will show you in 2 minutes only why MemophenolTM is the product you have been looking for" says Cécile FREMONT, Communication manager of ACTIV'INSIDE.
Expert in saffron (crocus sativus L.) and grape (vitis vinifera L.) raw materials, the French biotech company ACTIV'INSIDE knows their compositions and applications more than anyone else. ACTIV'INSIDE proposes a large range of signature saffron and grape extracts, premium quality, including organic, vegan, kosher and halal ones. The company also valorises saffron and grape health benefits by developing proprietary natural active solutions, based on strong scientific background and clinically proven efficacy. 3 actives solutions dedicated to 3 majors application are available: Cognition, Mood and Skin beauty. Furthermore, if you want to be helped in the development of your finished products, ACTIV'INSIDE also proposes private labelling with its ingredients.


If you're promoting a newsletter, book or even yourself, a good press release is an essential tool. A well constructed press release can get your name out quickly.
1. A good release should get you exposure on the community calendar or the FYI sidebar in newsprint.
2. It should get you a response by phone or by email. Often the newspaper, radio station or website will contact you for clarification or sometimes an interview.
3. Your release should be ready to print. If you do the work for them, they are more likely to use it in print. They can just plug it in and go. That saves them time and money.
You need to keep it brief, but eye catching!
Put the WHO, WHAT, WHERE, WHEN in the first paragraph in an exciting and refreshing way.
Boring: Kathy Stemke will be reading her book at the Cornelia Library on Thursday, August 4, 2011.
Creative way to give the same information: Story telling is a lost art. Children learn about relationships, their community and how things work through stories. Retired teacher and author, Kathy Stemke, showcases her craft Thursday, August 4th at the Cornelia Library.
The rest of the release should show why people should attend and why they should be interested in Kathy Stemke.
Example: Kathy Stemke has a B.S. from Southern Connecticut State University and Covenant Life Seminary, as well as graduate coursework from New York Institute of Technology and Columbia University. Hanging her hat in the North Georgia mountains, she has been a dancer, choreographer, teacher, tutor, writer and antiques dealer for many years. As a freelance writer and ghostwriter, Kathy has published hundreds of articles in directories, websites and magazines. She is a reviewer for Sylvan Dell Publishing. As a retired teacher, Kathy has several activities published with Gryphon House Publishing.
Kathy's first e-book, Moving Through All Seven Days, is now available on Lulu. Trouble on Earth Day, a picture book about recycling and Sh Sh Sh Let the baby Sleep a picture book that deals with sibling relationships and consonant blends are also available.
The closing of your press release should be specifically about who the release represents. If it represents the library, you want to give the specific address and phone information so people can contact them with questions. If the release is from Kathy Stemke, she should add a phone number, email address and website address.
Keep it to one page! Just remember, if they want more, they will ask for it. Fill the space at the bottom of the page with contact numbers. Edit well and submit a clean copy.
A picture is worth a thousand words. Every medium loves photos. If you are submitting a photo please identify everyone in it, left to right, front row, back row. You must have photo releases available. If you submit a photo by email, make sure it is very high resolution. If you submit a snapshot by mail, make sure it is not your one and only copy, because with some newsrooms you will never see it again.
Better still, offer the paper a photo opportunity - you with your award, you accepting your award, or you signing your books for your fans.
If you have published a new book, suggest a giveaway--a write-in competition with a couple of copies of your book as prizes.
Kathy -- really helpful comments to keep in mind when writing a press release, and great list of sites to post it. Thanks for the great post.
Kathy, great information! Thanks for sharing.
Well done with terrific information.


So I went to New Zealand a couple weeks back to speak at a conference with the creative director of Adbusters, Pedro and the senior editor, Darren. New Zealand is amazing.
You'll be in these amazing places and be pretty much the only people there.
Pedro and I went to the zoo.
All the animals in there, I could have watched them all day. These turtles kept climbing over each other and they could never make it work but they still kept doing it over and over.
I went to a place 3 hours away from Auckland called Rotorua. There is a lot of geothermal and volcanic activity, geysers, sulphur pools, all that kind of stuff there.
I went to go see this geyser and in the brochure it said, the geyser erupts daily at 10:15am. I was amazed and really curious as to how they could time the eruption of the geyser (especially to the minute). Turns out, they actually stick this biodegradable chemical thing down the rocks to make the geyser go (although the geyser does go off naturally on its own, just not when anyone is conveniently around).
I went to this other place called Waitomo, where there are a bunch of glowworm caves and caves with stalactites and stalagmites. And a population of 42 people. Most of which who work as tour guides for the caves. I really liked it there, you would see more wild turkeys running around in a place then people.
David Attenborough was in this very cave. Or so I am told. It was funny. The cave was like being in space mountain. Even funnier, because the cave is so small, you're on this raft, and they take you back and forth 5 times so that you have enough time to experience seeing the worms. It was weird. But nice.
Back in Auckland, there were these art installations going on. This thing was cool cause I felt like I was in Tron.
The funniest thing I saw in Auckland.
The scariest/weirdest thing I saw in Auckland.
The most elongated siamese cat I've seen.
I liked this light shadow because it looked like the carpet was worn at this one spot.
I don't really know how to explain how I felt about New Zealand. Being there, it was nice because you felt really separated from the world, but still part of it at the same time because of the time difference. The world's day begins and ends there. Things are a bit slower there, but at the same time there's all these things there that you have at home and that get you wanting to live and act like you do at home, but the experiences don't quite match up and there's weird disconnects - like that they have a Denny's there. There is something kind and well meaning about the place, something small and manageable, everyone is so nice, and at the same time there are these great expanses, ones to get lost in, to get sentimental in - and oh man I hope I get to go back there again.


text:
Sir John's Bungalow
Home / Accommodation / Sir John's Bungalow
Sir John's Bungalow is a refurbished century-old planter's bungalow set in the remote village of Riverston within Sri Lanka's Knuckles Conservation Range. It is surrounded by picturesque mountains and is well-liked for its simple but comfortable accommodation. Originally the residence of a British tea planter who managed the surrounding estate, this colonial-period bungalow is now a five-bedroom guesthouse blessed by numerous birds and other wildlife, including wild buffalo, barking deer, fishing cats, mongoose and occasionally the elusive leopard. During the dry season from June to September, wild elephants wander about the estate in search of water. Sir John's Bungalow retains its old-world charm, with hardwood floors and a fire place in the living room, and has comfortable bedrooms and courteous service. The property follows a strict eco-friendly philosophy, harnessing solar energy for electricity and using water channelled from a spring in the mountains.
There are five bedrooms, furnished with twin or double beds, which have spectacular mountain views.
Veranda Wing Rooms: Of the three bedrooms, two are triples and one is a double. All three rooms open onto the veranda where breakfast is usually served. The attached bathrooms have h/w showers.
Sirigiya View Room: A spacious family room furnished with three single beds and a double bed. Equipped with a flat screen TV with satellite channels. The attached bathroom has a cast-iron bathtub and h/w shower.
Sir John's Room: This master suite has one double bed and a single bed. The bathroom with a cast-iron bathtub and h/w shower is located a level below, accessed via a wooden staircase, so this room is not suitable for those with mobility difficulties. There is a flat-screen TV with satellite channels.
Traditional Sri Lankan rice and curry and western cuisine are on offer, prepared with fresh vegetables and other produce from the nearby town. As Sir John's Bungalow is in a remote area, it is best to discuss your meal preferences ahead of time with the chef who will ensure that tasty meals are prepared to your liking. Whilst breakfast is served on the veranda, lunch and dinner is hosted in the main dining room which has a ten-seater table and some smaller tables. Fresh juices, Ceylon tea and coffee are on offer and guests are welcome to bring their own alcoholic beverages. Other facilities include books on Sri Lanka's wildlife and nature, board games, room service and a doctor-on-call. Mobile phone connections tend to be erratic in this mountainous area, but there is a landline in case of an emergency. Sir John's Bungalow has a team of helpful staff, headed by the manager who is also an experienced naturalist. He has a thorough understanding of the fauna and flora of this region as well as other parts of the island and is ever-willing to share his knowledge with guests.
This slightly dated colonial-style bungalow gives a satisfing sense of isolation deep in the Knuckles mountain range
Sir John's Bungalow, about 1,000 feet above sea level, lies in the remote village of Riverston within the Knuckles Conservation Range, about 45 minutes north east of Matale. It is about two hours from Kandy.
Location: Knuckles, Kandy
Style: Guesthouse
Key Features: Colonial-style architecture; isolated setting


text:
est un film japonais réalisé par Yōji Yamada et sorti en 1974. C'est le  film de la série C'est dur d'être un homme.

Synopsis

Fiche technique
 Titre : C'est dur d'être un homme : La Maladie d'amour
 Titre original :
 Réalisation : Yōji Yamada
 Scénario : Yōji Yamada et Yoshitaka Asama
 Photographie :
 Montage :
 Musique : Naozumi Yamamoto
 Décors : Kiminobu Satō
 Producteur : Kiyoshi Shimazu
 Société de production : Shōchiku
 Pays de production :
 Langue originale : japonais
 Format : couleur — 2,35:1 — 35 mm — son mono
 Genres : comédie dramatique ; romance
 Durée : 104 minutes (métrage : sept bobines - )
 Dates de sortie :
 Japon :

Distribution
 Kiyoshi Atsumi : Torajirō Kuruma / Tora-san
 Chieko Baishō : Sakura Suwa, sa demi-sœur
 Tatsuo Matsumura : Ryūzō Kuruma, son oncle
  : Tsune Kuruma, sa tante
  : Hiroshi Suwa, le mari de Sakura
 Hayato Nakamura : Mitsuo Suwa, le fils de Sakura et de Hiroshi
 Sayuri Yoshinaga : Utako
 Seiji Miyaguchi : Shūkichi Takami, le père d'Utako
  : la belle-mère d'Utako
  : Kinuyo
  : Umetarō Katsura, le voisin imprimeur
  : Genko
 Chishū Ryū : Gozen-sama, le grand prêtre

Notes et références

Voir aussi

Articles connexes
 C'est dur d'être un homme (série de films)

Liens externes

  Site web officiel

Film japonais sorti en 1974
Comédie dramatique japonaise
Film en japonais
Film de Shōchiku
Film se déroulant à Tokyo
Film se déroulant dans la préfecture de Shimane
Film réalisé par Yōji Yamada
Suite de film japonais
Film C'est dur d'être un homme


How to frame your shot: when you're shooting your own video, the first thing you will need is a decent tripod-or a hackeysack and a stack of books. Steve Diguer (@TorontoPRJ) and Christine McGlade (@cmcglade) chat about things to keep in mind when you're going solo on your Youtube content production, and focus in on how best to frame and setup your shot.
In Webmaster101, Christine and Steve are joined by Ryan Payne, Founder and CEO of Lush Concepts, to talk about Responsive Design. What it is, why it matters, and how it has worked for client Ellie Tesher.
The ChargerCity looks good but DO NOT DO WHAT THEY SHOW IN THE PHOTO!!! Turn your phone sideways or Steve will freak out. Seriously.
Here's a nice-looking Octopus stand tripod.
© 2018 Analytical Engine Interactive Inc. All rights reserved.


Bajaj Qute the smallest car or first quadricycle in India is powered by 217cc, single cylinder, water cooled DTSi, 4 valve, triple spark petrol engine that generates a maximum power of 13bhp at 5500rpm and a peak torque of 19.6Nm at 4000rpm. Paired to a 5 speed manual gearbox and sequential gear shift is like motorcycle. Bajaj Qute returns a smart mileake of 36 kilometer per litre. Ground clearance of the vehicle is 180mm. Kerb weight of the vehicle is 399Kg. Boot space of the vehicle is 44 litres. Fuel tank capacity of the vehicle is 8 litres. Seating capacity of the vehicle is driver plus 3 passengers. Braking duties are handled by 180mm drum brakes at front and rear. Suspension duties are handled by independent suspension with twin leading arm at front and independent suspension with coil spring and semi trailing arm at rear. Tyres are 12 inch tubeless tyres.
Overall length of bajaj qute is 2752mm, overall width of the vehicle is 1312mm and overall height of the vehicle is 1652mm. Wheelbase of the vehicle is 1925mm and minimum turning radius is 3.5 meters. Top speed of the vehicle is 70 kilometer per litre. Ex-showroom price of Bajaj qute is 2 lakh Indian rupee.


text:
Q: How to load properties file only once? I am reading the email message by getting the data from properties file.I am using timer schedule to read the new message after some time at regular interval.How can i do this?
TimerSchedule.java
public class TimeScheduler
{
    public static void main(String[] args)
    {
        Timer timer = new Timer();
        GmailConfiguration gmailConfiguration = new GmailConfiguration();
        TimerTask timerTask = new TimerTask()
        {
            @Override
            public void run()
            {
                gmailConfiguration.configure();
            }
        };
        timer.scheduleAtFixedRate(timerTask, 500, 30000);
    }
}

I am getting data from properties file in GmailConfiguration.java
Here is my GmailConfiguration.java
public class GmailConfiguration
{
    private static final Logger LOGGER = LoggerFactory.getLogger(GmailConfiguration.class);

    public void configure()
    {
        JSONParser parser = new JSONParser();
        try
        {
            String propertyFileName = "emailServer.properties";
            InputStream inputStream = getClass().getClassLoader().getResourceAsStream(propertyFileName);

            JSONObject jsonObject = (JSONObject) parser.parse(new InputStreamReader(inputStream, StandardCharsets.UTF_8));
            JSONArray jadata = (JSONArray) jsonObject.get("Servers");
            int len = jadata.size();
            AccessMailMessages readGmail = new AccessMailMessages();
            JSONObject server;
            String name;
            String host;
            String username;
            String password;
            int port;
            String folderName;
            for (int i = 0; i < len; i++)
            {
                server = (JSONObject) jadata.get(i);
                name = (String) server.get("Name");
                host = (String) server.get("Host");
                username = (String) server.get("UserName");
                password = (String) server.get("Password");
                port = ((Long) server.get("Port")).intValue();
                folderName = (String) server.get("FolderName");

                readGmail.recieveGmail(name, host, port, username, password, folderName);
            }

        }
        catch (Exception e)
        {
            LOGGER.error("Exception", e);
        }
    }

}

A: Separate the Configuration class from the EmailReceiver class:
// Utilizes "Singleton" pattern
class GmailConfiguration {
  private static final GmailConfiguration INSTANCE = new GmailConfiguration();

  boolean isConfigured;
  String host;
  String port;
  //etc.

  public void configure() {
    if (!isConfigured) {
      // read in the properties, populate host/port etc.
      isConfigured = true;
    }
    // when called for the second time, reading won't happen
  }
}

then, as for receiving the email:
class GmailReceiver {
  public void receive() {
    AccessMailMessages readGmail = new AccessMailMessages();
    GmailConfiguration config = GmailConfiguration.INSTANCE;
    config.configure();
    readGmail.recieveGmail(config.getName(),
        config.getHost(),
        config.getPort() /* etc */);

  }
}

and make sure to only schedule GmailReceiver

redpajama_set_name: RedPajamaStackExchange


I 'm not a Tec Diver so what can Tec Diving do for me?
If you want to dip your toe in, but aren't sure about getting wet, why not sign up for the Sidemount Diver course. While Sidemount is not a tec course it does cover everything we have been talking about above.
The Tec 40 Diver course can be completed on a single cylinder and pony set up, sidemount or backmount doubles and is an ideal introduction to the equipment and training concepts of tec diving. The course can be used as a way to increase your skills and knowledge without needing to dive any deeper or longer than a PADI Deep Diver does or it can be a stepping stone into further TecRec training if you get bitten by the tec bug.
Next PostNext Cool like Fonzie?


Brier System Pvt. Ltd. industry tags is/are Chutes-Garbage And Living Others, The Address of the Brier System Pvt. Ltd. is J-4, KOTHARI COMPOUND, TIKUJINI - WADI ROAD, MANPADA, THANE (W), Thane Maharashtra India 400610, You can contact on their officials Email Address- [Show_Email_ID] and contact no.- [Show_Phone_No] . or can visit their website - N/A for more information.
Name Brier System Pvt. Ltd.


New Berlin voters narrowly rejected the $25 million school referendum.
Voters in New Berlin on April 2 said no to a $25 million referendum.
The five-year, nonrecurring operational referendum would have given the school district permission to exceed the state-set revenue limit by $5 million per year from the 2019-20 through 2023-24 school years.
Voters shot down the measure by a vote of 6,196 to 5,572, according to unofficial tallies.
The funds would have gone toward paying off existing debt, funding long-range facility and operational plans, and retaining and attracting staff by paying fair and competitive wages, according to the district.
District Superintendent Joe Garza said putting a referendum on the ballot was not a decision the school board and administration took lightly.
"We knew there would be passionate people on both sides of the issue, and this vote demonstrates that was exactly the case," Garza said. "The additional taxpayer funds would have allowed us to continue on our upward trajectory and would have kept us from making disruptive changes to our educational structure or programming. But the community has made its choice, and as a result, the new school board will have many difficult decisions to make in the near future."
The district has avoided operational referendums by managing structural deficits for the past seven years, according to district officials, but will be facing its largest deficit yet — $2.3 million — for the 2019-20 fiscal year and has no way to address it without significantly impacting the current educational structure.
Many factors are causing the deficits, according to district officials, including annual debt payments of around $3.7 million for building Ronald Reagan Elementary and renovating New Berlin West High School.
Other reasons for the red ink, according to the district, include paying for other building upgrades within the operating budget, not levying to the maximum for several years, declining enrollment and rising costs.
Because the referendum failed, district officials have said the school board will continue to make budget cuts and spend its limited fund balance — the district's savings account — to balance the 2019-20 and future budgets.
Maintenance and long-range planning will continue to be deferred, according to the district.
Funding of planned technology, equipment and safety upgrades, as well as curriculum and instruction resources, will be put on hold or remain on hold, district officials said.
Other cost-saving measures to be considered include possible staff reductions and consolidation of schools.