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The Nobel Prize in Chemistry 2020
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Jennifer A. Doudna
The Nobel Prize in Chemistry 2020 - Popular information
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Press release: The Nobel Prize in Chemistry 2020
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Popular science background:
Genetic scissors: a tool for rewriting the code of life (pdf)
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Gensaxen: ett redskap för att förändra livets kod (pdf)
Genetic scissors: a tool for rewriting the code of life
Emmanuelle Charpentier and Jennifer Doudna are awarded the Nobel Prize in Chemistry 2020 for discovering one of gene technology's sharpest tools: the CRISPR/Cas9 genetic scissors. Researchers can use these to change the DNA of animals, plants and microorganisms with extremely high precision. This technology has revolutionised the molecular life sciences, brought new opportunities for plant breeding, is contributing to innovative cancer therapies and may make the dream of curing inherited diseases come true.
One of the attractions of science is that it is unpredictable – you can never know in advance where an idea or a question may lead. Sometimes a curious mind will meet a dead end, sometimes it will encounter a thorny labyrinth that takes years to navigate. But, now and again, she realises she is the first person ever to gaze upon a horizon of untold possibility.
The gene editor called CRISPR-Cas9 is one such unexpected discovery with breathtaking potential. When Emmanuelle Charpentier and Jennifer Doudna started investigating the immune system of a Streptococcus bacterium, one idea was that they could perhaps develop a new form of antibiotic. Instead, they discovered a molecular tool that can be used to make precise incisions in genetic material, making it possible to easily change the code of life.
Figure 1. Using the genetic scissors, researchers can edit the genome of practically all living things.
A powerful tool that affects everyone
Just eight years after their discovery, these genetic scissors have reshaped the life sciences. Biochemists and cell biologists can now easily investigate the functions of different genes and their possible role in the progression of disease. In plant breeding, researchers can give plants specific characteristics, such as the ability to withstand drought in a warmer climate. In medicine, this gene editor is contributing to new cancer therapies and the first studies attempting to cure inherited diseases.
There are almost endless examples of how CRISPR-Cas9 could be used, which also include unethical applications. As with all powerful technology, these genetic scissors need to be regulated. More on that later.
In 2011, neither Emmanuelle Charpentier nor Jennifer Doudna had any idea that their first meeting, in a café in Puerto Rico, was a life-changing encounter. We will start by presenting Charpentier, who initially proposed their collaboration.
Charpentier is fascinated by pathogenic bacteria
Some people have called her driven, attentive and thorough. Others say that Emmanuelle Charpentier always looks for the unexpected. Herself, she quotes Louis Pasteur, "Chance favours the prepared mind". The urge to make new discoveries and the desire to be free and independent have governed her path. Including her doctoral studies at the Institut Pasteur in Paris, she has lived in five different countries, seven different cities and worked at ten different institutions.
Her surroundings and approaches have shifted, but the majority of her research has one common denominator: pathogenic bacteria. Why are they so aggressive? How do they develop their resistance to antibiotics? And is it possible to find new treatments that can stop their progress?
In 2002, when Emmanuelle Charpentier started her own research group at the University of Vienna, she focused on one of the bacteria that cause the greatest harm to humanity: Streptococcus pyogenes. Every year, it infects millions of people, often causing easily treatable infections such as tonsillitis and impetigo. However, it can also cause life-threatening sepsis and break down the soft tissues in the body, giving it a reputation as a 'flesh eater'.
To better understand S. pyogenes, Charpentier began by thoroughly investigating how this bacterium's genes are regulated. This decision was the first step on the path to the discovery of the genetic scissors – but before we walk further along that road, we will find out more about Jennifer Doudna. Because while Charpentier is making detailed studies of S. pyogenes, Doudna hears – for the first time – an abbreviation that she thinks sounds like crisper.
Science – as much adventure as a detective story
Even as a child growing up on Hawaii, Jennifer Doudna had a strong urge to know things. One day, her father placed James Watson's book The Double Helix on her bed. This detective-style story about how James Watson and Francis Crick solved the structure of the DNA molecule was like nothing she had read in her school textbooks. She was captivated by the scientific process and realised that science is more than just facts.
However, when she started to solve scientific mysteries, her attention was not on DNA, but on its molecular sibling: RNA. In 2006 – when we meet her – she is leading a research group at the University of California, Berkeley, and has two decades' experience of working with RNA. She has a reputation as a successful researcher with a nose for ground-breaking projects, and has recently entered an exciting new field: RNA interference.
For many years, researchers had believed that they understood the basic function of RNA, but they suddenly discovered lots of small RNA molecules that help regulate gene activity in cells. Jennifer Doudna's involvement in RNA interference is the reason why, in 2006, she gets a phone call from a colleague in a different department.
Bacteria carry an ancient immune system
Her colleague, who is a microbiologist, tells Doudna about a new discovery: when researchers compare the genetic material of vastly different bacteria, as well as archaea (a type of microorganism), they find repetitive DNA sequences that are surprisingly well preserved. The same code appears over and over again, but between the repetitions there are unique sequences that differ (figure 2). It is like the same word is being repeated between each unique sentence in a book.
These arrays of repeated sequences are called clustered regularly interspaced short palindromic repeats, abbreviated as CRISPR. The interesting thing is that the unique, non-repetitive sequences in CRISPR appear to match the genetic code of various viruses, so the current thinking is that this is one part of an ancient immune system that protects bacteria and archaea from viruses. The hypothesis is that if a bacterium has succeeded in surviving a virus infection, it adds a piece of the virus' genetic code into its genome as a memory of the infection.
No one yet knows how all this works, says her colleague, but the suspicion is that the mechanism used by bacteria to neutralise a virus is similar to that studied by Doudna: RNA interference.
Doudna maps a complex machinery
This news is both remarkable and thrilling. If it is true that bacteria have an ancient immune system, then this is a big deal. Jennifer Doudna's sense of molecular intrigue comes to life and she starts to learn everything she can about the CRISPR system.
It turns out that, in addition to the CRISPR sequences, researchers have discovered special genes that they have called CRISPR-associated, abbreviated as cas. What Doudna finds interesting is that these genes are very similar to genes that code for already known proteins that specialise in unwinding and cutting up DNA. So do the Cas proteins have the same function? Do they cleave virus DNA?
She puts her research group to work and, after a few years, they have succeeded in revealing the function of several different Cas proteins. In parallel, a handful of other research groups at other universities are studying the newly discovered CRISPR/Cas system. Their mapping shows that bacteria's immune systems can take very different forms. The CRISPR/Cas system studied by Doudna belongs to class 1; it is a complex machinery that requires many different Cas proteins to disarm a virus. The class 2 systems are significantly simpler because they need fewer proteins. In another part of the world, Emmanuelle Charpentier has just come across such a system. Back to her.
A new and unknown piece of the CRISPR-system puzzle
When we left Emmanuelle Charpentier she was living in Vienna, but in 2009 she moved to a position with good research opportunities at Umeå University in the north of Sweden. She was warned about moving to such a remote part of the world, but the long, dark winter allows her plenty of peace and quiet for work.
And she needs it. She is also interested in small, gene-regulating RNA molecules and, working with researchers in Berlin, she has mapped the small RNAs found in S. pyogenes. The results have given her a lot to think about, because one of the small RNA molecules that exists in large amounts in this bacterium is an as yet unknown variant, and the genetic code for this RNA is very close to the peculiar CRISPR sequence in the bacterium's genome.
The similarities between the two make Charpentier suspect that they are linked. Careful analysis of their genetic codes also reveals that one part of the small and unknown RNA molecule matches the part of CRISPR that is repeated. It is like finding two puzzle pieces that fit together perfectly (figure 2).
Charpentier had never worked with CRISPR, but her research group initiates some thorough microbiological detective work to map the CRISPR system in S. pyogenes. This system, which belongs to class 2, was already known to only require a single Cas protein, Cas9, to cleave virus DNA. Charpentier shows that the unknown RNA molecule, which is named trans-activating crispr RNA (tracrRNA), also has a decisive function; it is necessary for the long RNA that is created from the CRISPR sequence in the genome to mature into its active form (figure 2).
After intensive and targeted experimentation, Emmanuelle Charpentier publishes the discovery of tracrRNA in March 2011. She knows that she is on the heels of something very exciting. She has many years of experience in microbiology and in her continuing investigation of the CRISPR-Cas9 system she wants to cooperate with a biochemist. Jennifer Doudna is the natural choice. So that spring, when Charpentier is invited to a conference in Puerto Rico to talk about her findings, her aim is to meet this skilled Berkeley researcher.
A life-changing meeting in a Puerto Rican café
By coincidence, they meet at a café on the second day of the conference. A colleague of Doudna introduces them to each other and, the following day, Charpentier proposes that they should explore the old parts of the capital city together. As they stroll along the cobbled streets, they start talking about their research. Charpentier wonders whether Doudna is interested in a collaboration – would she like to participate in studying the function of Cas9 in S. pyogenes' simple class 2 system?
Jennifer Doudna is intrigued, and they and their colleagues make plans for the project via digital meetings. Their suspicion is that CRISPR-RNA is needed to identify a virus' DNA, and that Cas9 is the scissor that cuts off the DNA molecule. However, nothing happens when they test this in vitro. The DNA molecule remains intact. Why? Is something wrong with the experimental conditions? Or does Cas9 have an entirely different function?
After a great deal of brainstorming and numerous failed experiments, the researchers finally add tracrRNA to their tests. Previously, they believed that tracrRNA was only necessary when CRISPR-RNA was cleaved into its active form (figure 2), but once Cas9 had access to tracrRNA what every-one was waiting for actually happened: the DNA molecule was cleaved into two parts.
Evolutionary solutions have often surprised researchers, but this was something extraordinary. The weapon that streptococci have developed as a protection from viruses is simple and effective, even brilliant. The history of genetic scissors could have stopped here; Charpentier and Doudna had uncovered a fundamental mechanism in a bacterium that causes great suffering for humanity. That discovery was astounding in itself, but chance favours prepared minds.
An epoch-making experiment
The researchers decide to try to simplify the genetic scissors. Using their new knowledge about tracr-RNA and CRISPR-RNA, they figured out how to fuse the two into a single molecule, which they named guide RNA. With this simplified variant of the genetic scissors, they then undertake an epoch-making experiment: they investigate whether they can control this genetic tool so that it cuts the DNA at a location decided by the researchers.
By this time, the researchers know that they are close to a major breakthrough. They take a gene that is already in a freezer in Doudna's laboratory and select five different places where the gene should be cleaved. They then change the CRISPR part of the scissors so that its code matches the code where the cuts are to be made (figure 3). The result was overwhelming. The DNA molecules were cleaved in exactly the right places.
Genetic scissors change the life sciences
Soon after Emmanuelle Charpentier and Jennifer Doudna publish their discovery of the CRISPR/Cas9 genetic scissors in 2012, several research groups demonstrate that this tool can be used to modify the genome in cells from both mice and humans, leading to explosive development. Previously, changing the genes in a cell, plant or organism was time-consuming and sometimes impossible. Using the genetic scissors, researchers can – in principle – make cuts in whichever genome they wish. After this, it is easy to utilise the cell's natural systems for DNA repair so that they rewrite the code of life (figure 3).
Because this gene tool is so easy to use, it is now widespread in basic research. It is used to change the DNA of cells and laboratory animals for the purpose of understanding how different genes function and interact, such as during the course of a disease.
Genetic scissors have also become a standard tool in plant breeding. The methods previously used by researchers to modify plant genomes often required the addition of genes for antibiotic resistance. When the crops were planted, there was a risk of this antibiotic resistance spreading to the surrounding microorganisms. Thanks to the genetic scissors, researchers no longer need to use these older methods as they can now make very precise changes to the genome. Among other things, they have edited the genes that make rice absorb heavy metals from the soil, leading to improved rice varieties with lower levels of cadmium and arsenic. Researchers have also developed crops that better withstand drought in a warmer climate, and which resist insects and pests that would otherwise have to be dealt with using pesticides.
Hope of curing inherited diseases
In medicine, the genetic scissors are contributing to new immunotherapies for cancer and trials are underway to make a dream come true – curing inherited diseases. Researchers are already performing clinical trials to investigate whether they can use CRISPR/Cas9 to treat blood diseases such as sickle cell anaemia and beta thalassemia, as well as inherited eye diseases.
They are also developing methods for repairing genes in large organs, such as the brain and muscles. Animal experiments have shown that specially designed viruses can deliver the genetic scissors to the desired cells, treating models of devastating inherited diseases such as muscular dystrophy, spinal muscular atrophy and Huntington's disease. However, the technology needs further refinement before it can be tested on humans.
The power of genetic scissors requires regulation
Alongside all their benefits, genetic scissors can also be misused. For example, this tool can be used to create genetically modified embryos. However, for many years there have been laws and regulations that control the application of genetic engineering, which include prohibitions on modifying the human genome in a way that allows the changes to be inherited. Also, experiments that involve humans and animals must always be reviewed and approved by ethical committees before they are carried out.
One thing is certain: these genetic scissors affect us all. We will face new ethical issues, but this new tool may well contribute to solving many of the challenges now facing humanity. Through their discovery, Emmanuelle Charpentier and Jennifer Doudna developed a chemical tool that has taken life sciences into a new epoch. They have made us gaze out onto a vast horizon of unimagined potential and, along the way – as we explore this new land – we are guaranteed to make new and unexpected discoveries.
Additional information on this year's prizes, including a scientific background in English, is available on the website of the Royal Swedish Academy of Sciences, www.kva.se, and at www.nobelprize.org, where you can watch video footage of the press conferences, the Nobel Lectures and more. Information on exhibitions and activities related to the Nobel Prizes and the Prize in Economic Sciences is available at www.nobelprizemuseum.se
The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry 2020 to
Born 1968 in Juvisy-sur-Orge, France.
Ph.D. 1995 from Institut Pasteur, Paris,
France. Director of the Max Planck Unit
for the Science of Pathogens, Berlin,
Born 1964 in Washington, D.C, USA.
Ph.D. 1989 from Harvard Medical School,
Boston, USA. Professor at the University
of California, Berkeley, USA and Investigator,
Howard Hughes Medical Institute
"for the development of a method for genome editing"
Science Editors: Claes Gustafsson, Gunnar von Heijne, Pernilla Wittung Stafshede, the Nobel Committee for Chemistry
Text: Ann Fernholm
Translator: Clare Barnes
Illustrations: © Johan Jarnestad/The Royal Swedish Academy of Sciences
Editor: Sara Gustafsson
© The Royal Swedish Academy of Sciences
MLA style: Popular information. NobelPrize.org. Nobel Prize Outreach AB 2022. Wed. 19 Jan 2022. <https://www.nobelprize.org/prizes/chemistry/2020/popular-information/>


Of the procedures involving gastric sleeve are frequently performed through a laparoscopic procedure, using which a bariatric surgeon makes numerous smaller incisions in the belly, rather than earning a surgical cut to allow passing of the tools to use.
You may well be looking in to the sleeve gastrectomy, if you would like to drop a large amount of weight through operation. This is normally only performed on patients who are severely obese or have. You should think about the fundamental facts regarding it, if you believe you qualify for this particular treatment.
The point of this surgery is to get rid of the majority of the stomach which means you cannot eat much food, which ought to lead to significant weight loss within months. Once some of the belly is removed, the remaining is shaped to what looks like a sleeve. Your doctor could decide this operation is enough to assist you lose the weight that you will need to do away with. However, it may be combined with other procedures like for instance a gastric bypass or switch, in the long run. This can be determined on a case by case basis, which means you need to speak to your surgeon to determine if this surgery might be enough for you or if it's only the beginning.
During a sleeve gastrectomy, then your doctor can make several incisions. They just need to be large enough to permit a small camera to fit through, so they are usually small when comparing to typical incision. Once the camera is inside your body, your surgeon can quickly find out exactly what he or she's doing throughout the task, which should lead to safe results. At that point, much your stomach is going to probably be removed. The nerves will not be modified, nor will the remainder of your gastrointestinal tract. In this manner, this process is as non invasive as you can, especially in contrast to surgeries.
There really are a few advantages with this choice. The most important one is that you could reduce about 1 / 2 of one's own body weight. Your doctor and you may decide not or if another operation is warranted. The little incisions are more difficult to see which means that you will not be left with scarring that is noticeable. Furthermore, that the portion of one's stomach that will undoubtedly be removed is the part which features so you should not feel hungry even though you will eat a whole lot.
Your doctor can tell you when you're a fantastic candidate for sleeve gastrectomy. Otherwise, you can find you can be advised to avoid getting an surgery, or that another surgery could suit you even better. No matter what, you could get the responses you want from the doctor.


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TOPIC: My Question for the Jews
My Question for the Jews	12 Mar 2019 21:45	#1
My Question for the Jews (help me understand. I sincerely don't want to keep mocking you) - Owen Benjamin
You can't fix stupid
Only registered members can reply. Create an Account to join the discussion.
Name is Mick, Age 71, right winger, Christian, English
My main question for the Jews living in our countries is- why the hell don't you speak out against mass muslim immigration?
After all, muslims are the sworn enemies of Jews, so if Islam and Sharia Law ever takes hold, Jews will be the first to be rounded up for slaughter.
Below:- the midnight knock at the door in a future America, Britain, Australia etc-
"All Jews will come with us, NOW!"
User(s) who Liked this post: Rocco
Likes received: 5654
Ugh wrote:
They're not speaking out against mass muslim immigration, because it's the jews who are bringing them in.
As they use the muslims as a sledgehammer against Western civilization.
ww2truth.com/
My Question for the Jews	21 May 2019 06:24	#4
Why is Juden lineage being passed down through the female line when the Old Testament Bible has Hebrew lineage passed down through the male line?
Lineage was tracked through the males throughout the Bible. The only exception is in the case of Jesus because his father was God. You can see this in all the lineages where the fathers are listed. Mothers appear only rarely in such lists.
Modern Jews claim the use of maternal descent based on "Nor shall you make marriages with them. You shall not give your daughter to their son, nor take their daughter for your son. For they will turn your sons away from following Me, to serve other gods; so the anger of the LORD will be aroused against you and destroy you suddenly" (Deuteronomy 7:3-4). Since verse 4 mentions turning the sons (in plural) away, they claim that it is referring to the descendants of the marriage and thus the argument that the mother determines the lineage.
Sadly, it stretches the actual statement. God told the Israelites not to intermarry with a select set of nations (Deuteronomy 7:1-2), not all other nations. The warning was against either taking husbands or wives from these nations because they would turn people away from God. "Sons" is being used in a generic sense to refer to both the men and women.
Another verse used is "Now the son of an Israelite woman, whose father was an Egyptian, went out among the children of Israel; and this Israelite woman's son and a man of Israel fought each other in the camp" (Leviticus 24:10). They then point out that her son was counted as an Israelite.
What they ignore, however, are the cases where a descendant of Israel married non-Hebrew women and their children were counted as well. For example, Jacob, ancestor of the kings of Israel, had children by two non-Hebrew women. "And Judah saw there a daughter of a certain Canaanite whose name was Shua, and he married her and went in to her" (Genesis 38:2).
His second wife, Tamar, also appears to be not of Hebrew descent. Joseph's wife was an Egyptian and his two sons Manasseh and Ephraim were the founders of two of the tribes of Israel. The usual way of avoiding the obvious is to claim that these men's wives all converted to Judaism. Yet, could that not be claimed for the woman whose husband was an Egyptian?
Yet another argument is that in "And Shechaniah the son of Jehiel, one of the sons of Elam, spoke up and said to Ezra, "We have trespassed against our God, and have taken pagan wives from the peoples of the land; yet now there is hope in Israel in spite of this. Now therefore, let us make a covenant with our God to put away all these wives and those who have been born to them, according to the advice of my master and of those who tremble at the commandment of our God; and let it be done according to the law" (Ezra 10:2-3).
Much is made of only the men are mentioned as putting away their foreign wives and their children. The argument is that if the children were Israelites, they could not be put away. What is glossed over is that no child of certain nationalities could be counted as Israelites. "An Ammonite or Moabite shall not enter the assembly of the LORD; even to the tenth generation none of his descendants shall enter the assembly of the LORD forever" (Deuteronomy 23:3). Notice the "his," and understand that it is generic for male or female. If an Israelite woman married a Moabite man, their children would not be counted as Israelites either.
The maternal lineage is traced to the Mishnah (the Talmud), the codification of Jewish oral traditions.
"The Mishnah (Kiddushin 3:12) Talmud states that, to be a Jew, one must be either the child of a Jewish mother or a convert to Judaism".
www.lavistachurchofchrist.org/LVanswers/2010/04-05.html
"Women, slaves and children are exempt from the obligation to study Torah," Rambam writes. (Rambam, Hilkhot Talmud Torah 1:1)
It has been said and oft repeated that the reason why Juden lineage was changed from the Biblical Old Testament male lineage line to the Talmud Mishnah female line is because you never really know who the father of a child is but you always know who the mother of a child is.
It has been said that a lot of Juden babies were being born in circumstances where the father was not known so they were afraid of losing their 'nation' and so had lineage come through the female rather than the male.
It may well be but I think there could be deeper reasons for this change as well. It most certainly was and is not for reasons that have anything to do with respect for women's lineage or matriarchy as the Talmud is misogynistic.
Is there something within the Biblical male lineage framework that the Juden want to hide?
Luke12: 2-4
For there is nothing covered, that shall not be revealed; neither hid, that shall not be known.
Therefore whatsoever ye have spoken in darkness shall be heard in the light; and that which ye have spoken in the ear in closets shall be proclaimed upon the housetops.
And I say unto you my friends, Be not afraid of them that kill the body, and after that have no more that they can do.
User(s) who Liked this post: Flare
^ I like the way you say 'Juden'.
In regards to passing down Juden lineage through the male or female line.... doesn't it take 2 to tango or what?
Imo it's genetically being passed down through both parents.
In none of the manuscripts of the original Old or New Testament was Jesus described or referred to as a "Jew". The term originated in the late eighteenth century as an abbreviation of the term Judean and refers to a resident of Judea without regard to race or religion, just as the term "Texan" signifies a person living in Texas.
In spite of the powerful propaganda effort of the so-called "Jews", they have been unable to prove in recorded history that there is one record, prior to that period, of a race religion or nationality, referred to as "Jew". The religious sect in Judea, in the time of Jesus, to which self-styled "Jews" today refer to as "Jews", were known as "Pharisees". "Judaism" today and "Pharisaism" in the time of Jesus are the same.
Jesus abhorred and denounced "Pharisaism"; hence the words, "Woe unto you Scribes and Pharisees, Hypocrites, Ye Serpents, Ye Generation of Vipers".
www.biblebelievers.org.au/jesusjew.htm
I was reading yesterday that the Juden came up with the word 'Jew' as an inside joke, meaning 'half-Judean' ie..Ju/Jew. Or it could be as stated above an abbreviation of the word 'Judea'.
The thing is (as you know) the word 'Jew' didn't exist in language until the late 1700's so I have decided to not refer to them as 'Jews' as this just plays into the deception.
annabelle wrote:
That is true, but like is still the case in other languages than English, "jews" were referred to as "hebrews" (and variations thereof). The Hebrew language (autonym: Ivrit) was a near-dead language for centuries, only revived with the Zionist propaganda push (and historical fakery) of the mid-late 19th century.
By the time of the Roman Empire, Greek Hebraios could refer to the Jews in general, as Strong's Hebrew Dictionary puts it, "any of the Jewish Nation", and at other times more specifically to the Jews living in Judea. In early Christianity, the Greek term Ἑβραῖος refers to Jewish Christians as opposed to the gentile Christians and Judaizers (Acts 6:1 among others). Ἰουδαία is the province where the Temple was located.
See this map of Ukraine (1925). Jews are indicated as evrei:
The Only Limit is Your Own Imagination
A truth seeker is someone who dares to wade through thick series of toxic smoke screens and tries not to inhale - Gaia
"What do you call 'genius'?" "Well, seeing things others don't see. Or rather the invisible links between things." - Vladimir Nabokov (1938)
"The silence of conspiracy. Slaughtered on the altar of apathy." - Lords of the New Church (1982)
Last Edit: 21 May 2019 21:05 by Flare.
peacenik
...Then what shall we refer to those people who wrote the Torah (The first five books of the Old Testament) as?
Birth is not a beginning; death is not an end. There is existence without limitation; there is continuity without a starting point." ~ Chuang Tzu
Last Edit: 21 May 2019 22:01 by peacenik.
My Question for the Jews	22 May 2019 17:31	#10
Gaia wrote:
en.wikipedia.org/wiki/Hebrews]Hebrews
A Dire Warning About Dr. James Strong
Summary: James Strong of Strong's Concordance
1. Strong was a member of the Westcott and Hort Revised Version Committee (RV) of 1881 and worked in masterminding this corrupt version.
2. Strong was also a member of the American Standard Version Committee, finally published in 1901. It said that Jesus Christ was a creature, not the Creator.
3. On these committees Strong joined Unitarians (e.g. Thayer), a child molester (Vaughan), followers of Luciferian H.P. Blavatsky (e.g. Ginsburg, Schaff), and a horde of Bible critics (e.g. S. R. Driver), who together changed nearly 10,000 words of the text.
4. Strong's Concordance definitions are often the very words of these corrupt versions and also the Quran.
5. Strong also gathered his definitions from Gesenius' corrupt Hebrew Lexicon. His work also accesses the corrupt lexicons of Liddell-Scott, Thayer, Brown, Driver, and Briggs. All merit chapters in this book.
6. Strong's Greek text is not always that which underlies the King James Bible.
7. Strong's various definitions may not give anywhere near a literal translation of the Greek.
8. Some of the latest editions of Strong's Concordance are not even Strong's original. In the Greek and Hebrew lexicons in the back section, they contain even more corrupt definitions from new version editors. In the main body of the concordance, which originally was correct, new editions omit important KJB usages of the word 'Jesus' in order to match corrupt new versions.
James Strong's Concordance Greek and Hebrew Lexicon
James Strong (1822-1894), author of Strong's Concordance, has been elevated to the position of fourth member of the Trinity by many. His corrupt Greek and Hebrew definitions pepper today's preaching, as if his lexicon was the final and 67th book of the Bible. His liberal definitions are used as quick and weak patches to fill a void in sermons. The space would be better filled by a laborious looking up of all the Bible's usages of a word.
James Strong of the Corrupt RSV and ASV Committees
Strong's liberal views got him a Committee seat on the corrupt Revised Version (RV) of 1881 with Westcott, Hort, and Vaughan, as well as a seat on the American Standard Version (ASV) committee with Schaff and Unitarian J. Henry Thayer (finally published in 1901).
Westcott and Hort sought American Bible critics to join them in their work on the Revised Version. In 1870 the British Committee voted "to invite the cooperation of some American divines" (Matthew Brown Riddle, The Story of the Revised New Testament American Standard Edition, Philadelphia: The Sunday School Times, 1908, p. 11). Strong became "a member of the Old Testament company of revisers" (New Schaff-Herzog Encyclopedia of Religious Knowledge, New York: Funk and Wagnall's Company, vol. XI, p. 115).
Strong was hand-selected by American RV chairman Philip Schaff, who was also a participant in the new age Parliament of World Religions.
"The Rev. Philip Schaff, D.D., LL.D., Professor of Sacred Literature in The Union Theological Seminary, New York, by invitation of the English New Testament Company prepared a draft of rules for cooperation, and a list of names J STRONG DELUSION 163 of biblical scholars who should probably best represent the different denominations and literary institutions in this movement. The suggestions were submitted to the British Committee and substantially approved" (Introduction by Dr. Schaff to The Revision of the English Version of the New Testament, 1872).
Philip Schaff denied the inspiration of the Bible and only chose committeemen who agreed that the Bible had never been inspired; he called 'inspiration,' "the moonshine theory of the inerrant apostolic autographs" (See New Age Bible Versions for more details, p. 458; David Schaff, The Life of Phillip Schaff, NY: Scribner's Sons, 1897, pp. 439, 351, 357, 434-435).
Strong's Concordance Definitions
The definitions in the Greek and Hebrew Lexicon in the back of Strong's Concordance are often not literal renderings of the Greek or Hebrew word. For example, the Greek word deisidaimonia, used in Acts 17:22, is made up of two words, 'fear' and 'devil' (daimon). The King James correctly interprets 'fearing devils' as being "too superstitious." Propelled by views that 'other' religions are to be respected, the Strong's Concordance and his ASV pretend the word is "very religious." Both the ASV and Strong's Concordance turn a stern warning into a high compliment.
When reading the so-called definitions in Strong's Concordance (in the Greek and Hebrew Lexicons in the back), one is really often just reading Strong's corrupt American Standard Version (and sometimes also his 1881 Revised Version), which is now seen often in versions such as the NIV, NASB, NKJV, ESV, HCSB, NAB, NJB, et cetera. Note the following examples:
King James Bible —
Strong's Corrupt Lexicon Definition —
Strong's American Standard Version 1901 —
Godhead (King James Bible)
divinity (This is what it says in Strong's Corrupt Concordance)
divinity (This is what it says in Strong's American Standard Version)
one is your Master, even Christ
one is your teacher
too superstitious
very religious
bottomless pit
Hades 1.
demonic being 1., deity
morning-star
day-star
www.jesusisprecious.org/wolves/james_strong.htm
"A third contribution of the Parliament was to the Christian ecumenical movement. According to Diana L. Eck, the Parliament itself "might be seen as one of the first events of ecumenical movement" (1993, xv). Eck is not wrong given the fact that 152 of 194 speakers were Christians (Protestant, Orthodox, and Catholic) and that the "Christian flavor" was very obvious through the hymns, prayers and rhetoric during the Parliament. Barrows sometimes also discussed the necessity of Christian unity by employing the image of three concentric circle with "Christian assembly embodying its center; the American religious assembly, including Jews, comprising the next circle; and the religions of the worlds making up the outer circle" (Ziolkowski 1993, 57-8).
Among those who spoke on the subject of Christian unity, Philips Schaff was considered most authoritative (in Barrows 1893b, 1192-1201). While being critical of the organic or corporate model of ecumenism "under one government," he argued for a federal or confederate union, in which the balance between unity and independence could be maintained. However, the relevance of the Parliament to the ecumenical movement has not been recognized fully until the 1910 Conference of World Mission in Edinburgh. Thereafter, the ecumenical movement has always been dealing with the issues of religious plurality in connection with Christian unity and mission."
people.bu.edu/wwildman/bce/
Strong Delusion:
James Strong's Dangerous Definitions in the back of his Strong's Concordance
www.jesusisprecious.org/books/gail_riplinger/H-pp_157-202_Chapter_7_Strong_Delusion-James_Strongs_Dang.pdf
www.soulwinning.info/books/gail_riplinger/hazardous_materials.pdf
Last Edit: 22 May 2019 17:34 by annabelle.
True life is elsewhere
peacenik wrote:
Israelites.
What annanelle wrote isn't correct, Judea is not like Texas, ie evreyone in it is a Judean, it's named after Judah one of the tribes of Israel, the Jews are Judeans and generally thought to be spawn from Judah.
Judeans are Jews, it's as simple as that, even Mary is related to King David, what a star....
There were two main types of Judeans (Jews) the ones like the pharisees who were sort of subordinate to the Roman rule of the area, and then the messianic Jews, who would later be known as Christians who opposed the Romans with more effort, and didn't see eye to eye with the pharisees, it's Jewish infighting. They wouldn't hail Caesar but constantly be yelling 'messiah is coming' so politically and spiritually they had a separation but they were two groups of Jews with different opinions regarding compliance with the Romans and the notion of an imminent messiah.
At the end of the day, they're all Judah's children in that tribe, the NT is a book about them. Judah =Judean = Jew.
Jesus was referred to time and again in the NT as 'Rabbi' it's a Jewish tale..
He appeared with Moses and Elijah in the NT during his transfiguration, it's a Jewish book,, they have him a nudge of approval, it's a way of selling the idea to other Jews.
Once a hyena always a hyena.
Last Edit: 23 May 2019 21:10 by Frothy.
Yeshua (Jesus) was a nice Jewish boy, who any mother would be proud of. He was born in Bethlehem, as the Christmas cards show us, in very humble surroundings. After birth he had been circumcised and consecrated at the Temple and, by all accounts, had the typical childhood of one from a poor family in a Galileean village. And how do we know they were poor? "No room at the inn" was certainly a clue but the clincher was the "pair of doves or two young pigeons" that they sacrificed to the Lord after the birth. This was the pidyon ha-Ben, the redemption of a boy. It's an acknowledgement that every first-born boy belongs to God and all parents must "buy him back" by making a sacrifice. This rule dated right back to the time of Moses, when the first-born boys of the Israelites were spared from the Angel of Death on Passover night. Joseph and Mary were too poor to offer a lamb sacrifice and so were permitted to offer up the birds as a cheaper alternative.
www.premier.org.uk/Blogs/Yeshua-Explored/Jesus-the-Jew
Coo coo...
Kabbalists see the angelic Prince of the Face as intermediary between God and his people. Recalling R. Yitzhaq of Acre's equating of the afflicted Forerunner with the Messiah who saves Israel, the following passage from the Zohar almost sounds like an epitome of the New Testament's assertions about Yeshua's mediating, vicarious atonement:
When the Messiah hears of the great suffering of Israel in their dispersion, and of the wicked amongst them who seek not to know their Master, he weeps aloud . . . as it is written: "But he was wounded because of our transgression, he was crushed because of our iniquities" (Isaiah 53:5). . . . The Messiah . . . calls for all the diseases and pains and sufferings of Israel, bidding them settle on himself, which they do. . . . As long as Israel were in the Holy Land, by means of the Temple service and sacrifices they averted all evil diseases and afflictions from the world. Now it is the Messiah who is the means of averting them from mankind.
jewsforjesus.org/publications/issues/issues-v18-n02/kabbalahs-best-kept-secret/
A straight question directed at Jews 9.33 Thursday, 30 June 2016
Who "you" are, is no longer the question. The question is, who "IS" you. 6.82 Tuesday, 29 September 2015
Jews Did 911, Multiple Sources - AH and the Nazis Were Jews 5.81 Tuesday, 15 January 2019
A question for gm(o)p 5.49 Sunday, 16 July 2017
A question for BD. 5.49 Friday, 28 July 2017
Question for Annabelle 5.43 Friday, 30 December 2016
Question for "Antisemites" 5.43 Thursday, 27 June 2019
Stupid Question..... 5.43 Saturday, 12 July 2014
A question for Pfizi... 5.43 Sunday, 28 August 2016
More of a Question About The News... 5.43 Sunday, 27 October 2013
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redpajama_set_name: RedPajamaCommonCrawl


I am making a ball roller game.
I want to make it so that when the ball hits a certain object, it teleports to a certain location. I did this but when the ball teleports, it reaches the correct location but the ball just keeps spinning, like it was just continuing the movement from before it teleported.
I want to know how I can stop the ball from rolling after it teleports.
In your code when you teleport the ball stop the movement of the ball.
How would I stop the movement, what would I do in blueprints?
It would depend on how you are moving it. If you are moving it by force, add a set force node in the teleport and set it all to 0.


text:
Category Archives: church
Rila Monastery /Рилски Манастир
July 4, 2016 Bulgaria, Bulgarian, church, Eastern EuropeВалдис, Рилски, икон, манастир, fresco, icon, monastery, Rila, Valdisrisabuzatova
I visited the Rila Monastery the first time in September 1987. I was in Bulgaria to meet my future in-laws and they took me to what is certainly the most famous of monasteries in a country full of them and what is likely the most famous site in the entire country. We walked around within the monastery walls, admired the colors of the frescoes against the backdrop of the surrounding Rila Mountain. On a grassy spot just outside the monastery, we spread a blanket and lunched on the луканка (lukanka, hard salami), кашкавал (kashkaval, a cheddar-like cheese), tomatoes, and a hot loaf just baked in the monastery's ovens.
The second time I visited Rila Monastery was July 1, 2016. We stayed at the Valdis hotel and restaurant. It's not so much a hotel as a collection of modern bungalows set in a garden on the Rila River. Each has a small terrace looking onto the river and the mountain. We had river trout, potatoes with dill, and salad for dinner, French toast and steamed milk for breakfast. Across the way from Valdis is a fountain with water that flows down the Rila Mountain; we filled our water bottles there before setting off for the monastery above.
Rila's significance to Bulgaria and world culture, its church and iconography, its spiritual meaning for pilgrims, and the sheer physical beauty of its mountain location have all been amply described and photographed. But on this second visit, I noticed not the lushly painted icons, but the geometric almost Bauhaus style of decoration found everywhere outside the church itself. Reds and whites and blacks, geometric shapes, contrasts of metal, wood, stone, and brick.
All of this is beautifully contrasted with the pots of blooming flowers grown by the monks and the mountain forest rising all around their retreat.
I only wish the still-operating monastery ovens had been selling that delicious bread. That and the tiny post office remind you that however ancient the site, people still live and work here.
Sedmochislenitzi, the Center of Sofia
June 14, 2015 Bulgaria, Bulgarian, church, park, SofiaГраф Игнатиев, Седмочисленици, Graf Ignatiev, Petko Karavelov, Sedmochislenitzirisabuzatova
Sedmochislenitzi (Seven Saints) is a park and playground located almost dead center in Sofia. It is named after the church of the same name standing in the park's main square. We've been there countless times. A long market with many vendors borders one side on Graf Ignatiev Street. From fall into winter, there are not only seasonal fresh fruits and vegetables, but also pumpkins split in half, baked and sprinkled with cinnamon and walnuts. In mid- to late summer, you can buy clear, plastic drinking cups filled with raspberries and eat them with a tiny plastic fork. Summers, my son likes to stop at the corn vendor who sets up her cart at the park's entrance and get an ear of the steamed corn that is a popular snack. On the beach, vendors carry coolers, tongs, salt shakers and napkins, walking among the sunbathers calling "Tzarevitza molya" ("Corn please").
The church's site as a place of worship long predates its current incarnation. Before the Sedmochislenitzi church, there was the Koca Mehmed Paşa Mosque, built in 1528 and named after its patron and builder Sokollu Mehmed Paşa. Mehmed Paşa was originally from a small town in Bosnia, but he rose steadily and at age 59 reached the pinnacle of Grand Vizier, thus holding nearly absolute power and answerable only to the Sultan himself.
The Koca Mehmed Paşa Mosque began its evolution to the Sveti Sedmochislenitzi Church when on September 30, 1858, an earthquake struck just after noon prayers began. Although the epicenter was to the south, the magnitude seven earthquake caused severe damage in Sofia. The French Le Mémorial d'Aix reported that the earthquake "destroyed 35-40 stone houses, 20 minarets, a mosque, the barracks, and the local telegraph office." More than three weeks after the earthquake, reported Le Mémorial d'Aix, the aftershocks had not stopped and "the entire population had taken refuge in the squares and in the gardens." The minaret of the Koca Mehmed Paşa Mosque was one of those that collapsed. The mosque had to be abandoned.
After Bulgaria's 1878 liberation from the Ottoman Empire, the building was used as a military warehouse and prison. Bulgarian Prime Minister Petko Karavelov was imprisoned for three years in the mosque cum prison when his political opponents used various 1887 garrison uprisings as an excuse to get him out of the way. Back in power for the fourth and final time, he quite naturally led an effort to close the building and convert it to a church. The exterior maintains the three rows of thin dark red brick alternating with one thicker layer of stone, the original white mottled gray and brown with age, characteristic of medieval mosques and churches.
Less than a year after the church conversion was completed in 1902, Petko Karavelov died and was buried there. His grave and that of his wife abut the church building and are enclosed by wrought iron gates. There is no church cemetery. The asphalt plaza surrounding the church is full of young children racing past on bikes and scooters. Balls often bounce onto the grave and have to be retrieved.
My son was fascinated by the Orthodox priests we saw go in and out of Sedmochislenitzi Church. Bearded and often with long hair tied in a low ponytail, their black robes go down to their ankles. Orthodox priests may marry and we frequently saw a priest out walking with his wife and young children. Several times at my son's request, we walked into the church. On one of these occasions, an elderly priest with a full head of white hair greeted us and saw his interest in the bouquets of flowers set in vases. Father Ivan Mihov Nikolov gently took his hand, guided us to a small side room, and gave him several flowers from a vase there.
You can easily buy flowers from a florist store or streetside stand, but people often buy from one of the many older women who sit on packing crates near busy corners and in front of store windows. They sit behind large vases of different flowers and a few already made bouquets set down on the pavement. Such women specialize in flowers and are buying them wholesale to resell. Other older women set themselves up on packing crates near busy corners with what they've brought from their home gardens in nearby villages. They set up their wares on a box or a cloth and they don't need much room. Year-round, they come with what they have on hand. A big ball of celery root with its green shoots, two or three bags of dried legumes, and a few parsnips— pasternak in Bulgarian, just like the Nobel prize-winning author of Doctor Zhivago. A small bouquet or two of flowers, rose hip berries, bunches of parsley, preserves in re-used jars from long ago store-bought products, dried herbs collected from walks in village fields and mountains, liter bottles once filled with cola now with whole milk you must boil once you bring it home.
We enjoy Sedmochislenitzi as part of a large park with cafés at either end, gardens, playground, and enough car-free asphalt to allow city children to get full use of bicycles, skateboards and skates. The children play, we talk. Life at Sedmochislenitzi has an easy pace.
One Saturday, we went to Sedmochislenitzi. When we arrived, as often happened, a wedding was in progress and the wedding party was being photographed. This does not deter children, including mine, from skateboarding, running, jumping, chasing pigeons, biking, while the big day is being celebrated. No one minds—no one even comments or seems to notice. Elderly people hobbling through the park with canes are not deterred from slowly passing through as the bride is posing against the church walls and I'm quite certain there are wedding albums that include my daughter, son or both. Friends of both children were either already there or showed up shortly, and all had a grand time running around the church and playground. Then the proverbial "circle of life" showed itself as the wedding party dispersed. The next event on the Sedmochislenitzi church schedule was a funeral.
The priest began a prayer. Completely oblivious to the proceedings, my son and a friend were practically touching the hearse as they played. The casket inside was clearly visible as the windows were not blackened, smoked or otherwise made opaque. In the open casket, the dead man's head was raised up on a pillow, able to be seen clearly by not only me but by the children. The presiding priest stood looking at the casket and crossing himself. The children on the playground kept playing and the adults seemed entirely unperturbed by the proceedings. The day warmed up considerably from the morning's chill, the sun shone and we stayed on at Sedmochislenitzi for several hours before returning home.


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First we need the esphomeyaml code to capture the IR buttom press and send it to home assistant as a binary I/O. In this particular example we use the widgets button on the FiOS remote. This button is basically harmless in any state of the DVR so it can be easily overloaded as the light trigger.
Next we need an automation that responds to the IR button press and controls the lights.


text:
Great Britain: Enthusiasm For Scottish Parliament Wavers, But Devolution Still Popular
One of British Prime Minister Tony Blair's biggest reforms in his first term was to devolve some power from London to Scotland and Wales, which together with England make up Great Britain. The Scots have used their relative autonomy to scrap tuition fees for university students and provide free personal care for the elderly, much to the envy of some people in England. So admirers may be surprised to hear there were few celebrations when the devolved Scottish parliament marked its firs t 1,000 days recently, and that polls show Scots are disappointed with the accomplishments of their parliament so far.
Prague, 11 April 2002 (RFE/RL) -- When Scots voted for devolution in a 1997 referendum, plans were drawn up for a new parliament buildi ng in Edinburgh to house the 129 members of the Scottish Parliament -- or MSPs -- who would have a say in sectors such as Scotland's health, education, environment, and agriculture.
Five years later, that building is still not complete and is likely to cost some 500 million euros ($442 million) -- more than seven times the original estimate.
John Curtice is head of research in Scotland for the National Centre for Social Research, which has documented waning enthusiasm among Scots for their parliament. He says the fiasco of the Edinburgh building and its spiraling cost have become a "disastrous symbol" for the parliament since it was set up in 1999. But he says the main reason people are disappointed in the record of their MSPs is that expectations were so high to begin with. It's no surprise to find, as Curtice puts it, that "reality has kicked in."
One of the center's polls, conducted around the time of the 1997 referendum, found that 79 percent expected that the new parliament would give ordinary peo ple a bigger say in how Scotland is governed. Last year, however, only 38 percent said this had actually happened. Respondents said MSPs had failed in particular to deliver on education, following the near collapse of the Scottish exam system two years ag o.
Curtice says, "I would argue perhaps the most revealing thing is that when we ask people now who has the most influence over what happens in Scotland, two-thirds say the U.K. government in Westminster. There's the perception that the parliament is no t making the impact that one would expect, or at least the [impact that] advocates of devolution were expecting."
Tim Luckhurst, a former editor of one of Scotland's leading dailies, "The Scotsman," goes further. He cites a poll conducted this year by Sc ottish Television in which 96 percent of respondents believed the devolved parliament has performed badly throughout its existence. Luckhurst says Scots don't have to look far for the reasons.
"Their [MSPs'] interest [is] in causes that appear to have ab solutely no resonance with the general public and their constant, apparent desire to reward themselves for the simple act of being elected to office, rather than concerning themselves with issues that are of genuine public concern," says Luckhurst.
He li sts three issues that have preoccupied parliament but are of little general interest to voters: the ban on fox hunting, already a minority sport; the repeal of a clause banning the promotion of homosexuality in schools; and plans to outlaw corporal punish ment for small children.
It hasn't helped that MSPs last month awarded themselves a 13.5 percent pay raise, or that they're considering expensive furnishings for the yet-to-be-completed parliament building.
Scotland's lawmakers say they have made a diff erence to ordinary people's lives, giving them "a new voice in the land," in the words of Donald Dewar, Scotland's first minister until his death in 2000. They point to the abolition of university tuition fees and the introduction of free personal care fo r the elderly. And Curtice says much of what the parliament is good at -- like producing well-crafted legislation in committee -- is not the stuff of newspaper headlines.
James McKenzie, a spokesman for the Scottish Parliament, admits that "no one will s ay it's been perfect but a good start has been made." He says many of the big issues of the day are still dealt with in London, but that Scotland's MSPs have passed laws that do affect the lives of many people.
McKenzie pointed to legislation that the pa rliament adopted on domestic abuse, where restraining orders against violent partners can now be applied in cases where the couple are unmarried, or even gay.
As for whether topics such as fox hunting are trivial, McKenzie says this drew a huge amount o f interest from both supporters and opponents. "This is a minority sport," he says, "but it's something that many people have a strong opinion about."
But Luckhurst of "The Scotsman" says the university tuition and health-care policies are simply example s of the grandiose spending habits that MSPs learned while in local government.
"This is not evidence of bright, intelligent, radical thinking. It's evidence of people who have spent too much time in an environment in which money was not their problem. A ll funding came from central supply and therefore they didn't have to take responsibility for the taxation required to pay for their ambition. What we have got in Scotland, as even left-of-center academics agree, is an executive which has spent money with no thought for the future and which will have great difficulty financing these policies, not just in the long-term but even in the next few years," says Luckhurst.
But before Scotland's devolution experiment is consigned to the dustbin, it's worth notin g that the attitudes recorded in Curtice's surveys are actually fairly complex.
While people say they are unhappy or disappointed in their new parliament, there's still widespread support for the principle of devolution. And three-quarters now say parlia ment should have more powers, raising the question: Has devolution fueled, or quelled, separatist feeling in Scotland?
Scots have a strong sense of national identity, and even prior to devolution, their legal and educational systems were significantly different from those in England.
An opinion poll conducted earlier this month suggests that, with just over 12 months to go before the next Scottish elections, the pro-independence Scottish National Party is gaining ground on Labour, which is in coalition with the Liberal Democrats in the devolved government. The poll gave the SNP a lead in the proportional element of the election, and showed the party closing in on Labour in the first-past-the-post vote.
Luckhurst says devolution initially dented the SNP's fortunes but that the parliament has given the party an important forum. As he notes, the nationalists "only have to win once."
"In the long-term, what one has to recognize is that, with the creation of a devolved parliament, it is conceivable that a patriotic nationalist sentiment will eventually come to dominate, something that was entirely impossible while Scotland was governed by the union parliament," says Luckhurst.
There are also signs that some in England's regions are restive and want their own regional assemblies, too. A BBC poll last month showed this feeling is particularly strong in the regions bordering Scotland and Wales.
John Adams is a former Labour adviser on devolution and an expert on constitutional reform at London's Institute of Public Policy Research. He thinks it is quite likely that England's regions will get some form of devolution. Still, he says this should not shake the foundations of the union. In fact, he believes devolution has made the Scots more appreciative of the U.K.
"The fact that we're trying to develop a more devolved and diverse U.K. is a very good thing, and I think it strengthens our country rather than try to pretend we're all the same," says Adams.
Curtice suggests that, even as people in Britain incre asingly stress their national or regional identities, the post-devolution union is still robust. He notes that people are more likely to emphasize their Scottish, English, or Welsh identities, as opposed to their Britishness.
But ask them if they still want to be in the U.K., he adds, and a majority -- in England, Scotland and Wales -- say yes..


text:
Q: xml Spring config using values from properties files For DI in xml via setters using values from properties files I can use:
<beans>
..
   <bean class="org.springframework.beans.factory.config.PropertyPlaceholderConfigurer">
        <property name="location" value="props.properties"/>
    </bean>
    <bean id="first" class="..">
        <property name="name" value="${values.name}"/>
    </bean>

</beans>

But PropertyPlaceholderConfigurer class is deprecated.
I have tried to use
<context:property-placeholder location="classpath:props.properties"/>

instead of It but It didn't work
prop.properties in situated in resources, error message is no declaration can be found for element 'context:property-placeholder'

A: As per Javadocs of PropertyPlaceholderConfigurer

as of 5.2; use
  org.springframework.context.support.PropertySourcesPlaceholderConfigurer
  instead which is more flexible through taking advantage of the
  Environment and PropertySource mechanism

you can load property like below, you have to include namespace  & schemalocation in your beans tags. copy the beans tag from below
 <?xml version="1.0" encoding="UTF-8"?>
    <beans xmlns="http://www.springframework.org/schema/beans" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:context="http://www.springframework.org/schema/context"
            xmlns:util="http://www.springframework.org/schema/util"
            xsi:schemaLocation="
              http://www.springframework.org/schema/beans http://www.springframework.org/schema/beans/spring-beans-4.2.xsd
              http://www.springframework.org/schema/util http://www.springframework.org/schema/util/spring-util-4.2.xsd
              http://www.springframework.org/schema/context http://www.springframework.org/schema/context/spring-context-4.2.xsd">

 <context:property-placeholder location="classpath:foo.properties,classpath:bar.properties"/>

    </bean>

</beans>

redpajama_set_name: RedPajamaStackExchange


text:
South Korea : the wage gap between white and blue-collar workers increases
by Theresa Kim Hwa-young
The Korean economy is transforming : once based on heavy industry it is now powered by the service industry.
Seoul (AsiaNews) – The income gap between white and blue-collar workers widened further last year, reflecting that the income disparity is deepening. A report released by the National Statistical Office (NSO) Thursday showed that the average monthly income of white-collar workers or those who work in the office rose 2.8 percent to 2.98 million won (1 € = 1158,46 won) last year from 2.9 million won a year earlier. During the same period, the monthly income of blue-collar workers, or industrial workers rose by 2 percent to 1.62 million won in 2005 from 1.95 million won in 2004.
The wage gap between blue and white collar workers has been increasing now for some years, bringing with it serious socio-economic repercussions. Disparity has also increased, and the country's economic system has also transformed itself from one based on heavy industry to one based on the service industry.
The ratio of the average annual income of blue-collar workers to that of white-collar workers dropped to 54.6 percent last year from 55 percent in 2004 and 55.7 percent in 2003. There is also a large difference between the wage of university and high school graduates. The average annual income of wage earners with postgraduate school degrees averaged at 46.79 million won in 2005, while that of workers with high school diplomas stood at 24.8 million won. The gross annual income of wage earners holding bachelor's degrees averaged at 36.17 million won.
On monthly basis, the average income of salary workers who hold either a master's degree or a doctorate shrank 0.9 percent from 3.9 million won in 2005 from 3.93 million won of a year ago, while that of those who completed university studies increased 3.6 percent to 3.01 million won from 2.92 million won. The average monthly income of those who only graduated high schools also increased 3.5 percent.
11/02/2006 00:00:00 - East Asia South Korea


text:
Study shines light on gut microbiome in colon cancer
Washington, DC - May 15, 2018 - Researchers have identified a correlation between gut microbial composition and microRNA expression in human colorectal cancer, according to a recent study published in the journal mSystems. The study is the first to demonstrate that the interaction between microRNA and the gut microbiome may play a role in colorectal cancer.
"This is a correlation, but it is still very exciting, because if we see a causal effect, you can think of ways to manipulate the microRNA in the tumors by changing the microbiome, and that could potentially be used as a cancer therapy," said principal study investigator Ran Blekhman, PhD, assistant professor in the Departments of Genetics, Cell Biology and Development, and Ecology, Evolution, and Behavior, at the University of Minnesota, Twin Cities. The study was performed by Angelo Yuan, a Ph.D. student in the Bioinformatics and Computational Biology graduate program at the University of Minnesota.
The researchers launched their new study for three reasons. First, recent studies have shown that the microbiome has a role in colon cancer. Second, many studies have shown that host microRNAs are very important in cancer. Third, recent research has shown that there are interactions between the microbiome and host microRNAs. "We wanted to look at all of these things together, to see if there is any interaction between the host microRNA and the microbiome in the context of colon cancer," said Dr. Blekhman.
The researchers analyzed colon cancer patient samples collected as part of a previous study at the University of Minnesota. A total of 88 matched tumor and adjacent normal tissues were collected from 44 patients. The researchers sequenced the microRNA of these samples and correlated microRNA expression levels in colon cancer tissue with the microbiome composition.
The researchers found that dozens of microRNA are differentially regulated in colorectal cancer tumors, compared to adjacent normal colon, and that these microRNAs are correlated with the abundance of microbes in the tumor microenvironment. They also found that microbes that have been previously associated with colorectal cancer are correlated with microRNAs (microRNA-182, microRNA-503, microRNA17-92) that regulate genes related to interaction with microbes that likely regulate glycan production, which is important for the recruitment of pathogenic microbial taxa to the tumor.
"We found networks of microbes that are dependent on the microRNA. Then, we specifically investigated the microbes that have been previously linked to cancer, and we identified all of the microRNAs that are correlated with the abundance of these microbes," said Dr. Blekhman. "This is an exciting result, but for now, we have shown correlation. We are currently working to show a direct effect of the microbiome on the microRNA using animal models."
The research provides a first systems-level map of the association between microbes and host microRNAs in the context of colorectal cancer. Future efforts will aim to detect whether the correlations are causal and if they are, whether there are possibilities to manipulate the microbiome to regulate the expression of microRNAs in the tumor, potentially impacting tumor progression.
The American Society for Microbiology is the largest single life science society, composed of more than 30,000 scientists and health professionals. ASM's mission is to promote and advance the microbial sciences.
ASM advances the microbial sciences through conferences, publications, certifications and educational opportunities. It enhances laboratory capacity around the globe through training and resources. It provides a network for scientists in academia, industry and clinical settings. Additionally, ASM promotes a deeper understanding of the microbial sciences to diverse audiences.
Aleea Khan
communications@asmusa.org
@ASMnewsroom
http://www.asm.org


A Race Night is being held for the benefit of both our Camogie Club and the Hurling and Football Club and it is very important that we all support it as we need all the funds we can get. The date is March 11th, so you have plenty of notice.
Your Club needs you.....................Be there.


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It's that time of year again! If you are an incoming 6th, 7th, or 8th Grader, we want you to come to Forest Home for an amazing week of camp! We are headed to Creekside at Forest Home from July 7-12 to have tons of fun and worship together.


Facts: The applicant is a Lithuanian national employed by the Lithuanian armed forces. His contract was terminated because he had reached retirement age, in accordance with the legal provisions in force.
The applicant challenged this decision before the administrative courts, alleging that he had been discriminated against on grounds of his personal opinions, and asked the courts to obtain and analyse evidence of other soldiers in his battalion who should also have been dismissed on grounds of age. The applicant's complaints were dismissed and that decision was ultimately upheld by the Supreme Administrative Court.
Issue: The case was brought to the Court to decide whether there is a violation of Articles 6 § 1 (Right to a fair trial) and 10 (Freedom of expression) of the ECHR.
Holding: Yes, there has been a violation of Article 6 § 1 of the Convention.
No, there has been no violation of Article 10 of the convention.
Court's Rationale: The applicant was dissatisfied that when examining his complaint the administrative courts had ignored his repeated requests for access to the military files of four specific servicemen. On this point the Court observes that one of the elements of a fair hearing within the meaning of Article 6 § 1 is the right to adversarial proceedings.
The Court stated that a comparison between the applicant's situation and that of the other serviceman was indispensable for the applicant to be able to present his grievance.
The failure of the domestic courts to assist the applicant in obtaining evidence had denied the applicant an essential means to argue his case.
In disputes concerning civil rights, such as the present one, such a limited assessment could not be considered an effective judicial review under Article 6 § 1.
The proceedings taken as a whole did not satisfy the requirements of a fair and public hearing within the meaning of Article 6 § 1.


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Morgan Brenda Christen (born December 5, 1961) is an American lawyer and jurist who serves as a U.S. circuit judge of the U.S. Court of Appeals for the Ninth Circuit. She previously served as a state court judge on the Alaska Supreme Court from 2009 to 2012 and on the Alaska Superior Court from 2002 to 2009.

Early life, education, and legal career
Christen was born in 1961 in Chehalis, Washington. She graduated from the University of Washington in 1983 with a Bachelor of Arts degree in international studies. She then attended the Golden Gate University School of Law, graduating with a Juris Doctor in 1986.

After graduating from law school, Christen was a law clerk to Alaska Superior Court judge Brian Shortell from 1986 to 1987. From 1987 to 2002, she was in private practice at the law firm Preston Gates & Ellis, becoming a partner in 1993.

Judicial career

Alaska state judicial service
Christen was a judge on the Alaska Superior Court from 2002 to 2009. In 2009, she was one of two candidates recommended by the seven-member Alaska Judicial Council to replace Justice Warren Matthews on the Alaska Supreme Court. Christen was opposed by anti-abortion advocacy groups due to her service as a Planned Parenthood board member in the mid-1990s. Nonetheless, on March 4, 2009, Governor Sarah Palin selected Christen to fill the vacancy on the Alaska Supreme Court.

Federal judicial service

On May 18, 2011, President Barack Obama nominated Christen to the seat on the Ninth Circuit vacated by Andrew Kleinfeld, who assumed senior status on June 12, 2010. On September 8, 2011, the Senate Judiciary Committee reported her nomination out of committee by a voice vote. The Senate confirmed Christen by a 95–3 vote on December 15, 2011. She received her commission on January 11, 2012 and now maintains her chambers in Anchorage.

See also
List of first women lawyers and judges in Alaska

References

External links

1961 births
Living people
21st-century American judges
Justices of the Alaska Supreme Court
Golden Gate University School of Law alumni
Judges of the United States Court of Appeals for the Ninth Circuit
People from Chehalis, Washington
Superior court judges in the United States
United States court of appeals judges appointed by Barack Obama
University of Washington alumni
Women in Alaska politics
21st-century American women judges

redpajama_set_name: RedPajamaWikipedia


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Forex reports are issued on a daily basis for the general public to understand what is going on with the forex market. These reports are very helpful, not only to forex traders (which include banks and retail traders), but to anyone at all that is involved in commerce; which is almost the whole of human race. It is not secluded to a particular place or country generally as many countries foster international relationships through importation and exportation of goods and services.
In just one day, it was recorded that crude oil posted the largest one-day loss in one month; a sad news for investors. From the forex reports, Russia was said to oppose a greater cutback in production. This cutback is literally beyond the verge recognized in the existing OPEC-led output cut scheme.
This report brings into focus the EIA (Energy Information Administration) inventory data. According to the forecast, there is a suggested drawdown of 1.8 million barrels the week before, but according to the most recent API report publication following this suggestion, it was projected that a far larger 5.8 million barrels out flow over the same period.
Forex technical reports as recognized by the banks and the rest of forex traders worldwide have it that the EUR GBP currency pair is showing signs of major topping returns. The euro has got a range against the British pound, and just recently, it slipped into the lower half of this range. The candlestick pattern shows a bearish dark cloud cover, hinting a larger double top chart set up, may be brewing.
Despite all that, the EUR GBP remains one of the top trades for 2017 as could be seen in the forecasts made by professional forex traders.
It is on record that this pair had a constant uptrend for the past one month. Another report has been set to make it official that the one month uptrend of the AUD USD has been broken. From the look of things, the AUD may most likely loose against the USD as a result of its vulnerable stance at the moment. Before the trend turned lower, it put in a bearish evening star candlestick pattern below resistance, capping gains since April 2016.


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Looks like a veggie pizza with sausage, right? Wrong.
The sausage -- and the twist -- is 100% Bran cereal.
When I happened upon the recipe in a 1984 church cookbook, I knew it would either be awful or delicious. Wrong. And wrong.
It was however quite good and somehow hit just the right retro note on a warm Friday evening.
The bran is barely detectable except on top where it's chewy, crunchy and delightfully nutty (in more ways than one).
Preheat the oven to 450F. Whisk the eggs in a large bowl, then add the remaining ingredients in a large bowl. Transfer to a 9-inch pie plate sprayed with cooking spray. Bake for 8 minutes.
Combine these ingredients in the same bowl. Sprinkle HALF of it over the slightly baked pie.
Spread the mozzarella evenly over the pie, then arrange the tomato slices across the entire pie. Arrange the zucchini around the outside edge, then arrange the remaining cheese/bran mixture from STEP TWO in the middle.
Reduce the oven temperature to 350F. (I forgot to do this.) The recipe says to bake another 20 - 25 minutes. Last night's took 25 minutes, even at 450F. Slice and serve.
Another time, I might add an egg or two (or Egg Beaters) to make this more quiche-like.
While it wouldn't be as retro, I'd also add fresh basil.


text:
Petrophila tessimalis is a moth in the family Crambidae. It was described by Harrison Gray Dyar Jr. in 1926. It is found in Mexico.

References

Petrophila
Moths described in 1926


In an interesting interview with the Risk & Compliance Journal, David Hoffman, forensic accountant and managing director at Acuitas, Inc. discusses the status of the lawsuits that resulted from the bank failures that occurred in the years following the economic crisis of 2008. At the close of 2013, there were 81 lawsuits involving 127 different banks. Hoffman discusses his role as a forensic investigator in the proceedings, drawing similarities between the current situation and the S&L crisis of the 1980's. He also shares his view of how current regulations impact his responsibilities within the investigative process and the part technology plays in advancing forensic accounting techniques.


Although there was no deluge to delay our return home, we did get lost on a dark golf course on our long journey from "Fireworks Hill" to the place where our car was parked. It's rare to have much grass underfoot in Tucson, so getting to sport about on the slope was a lot of fun. In fact, the distressingly high admission fees charged by the El Conquistador resort are easier to justify for that reason -- the chance to violate the sacred greensward of the golfing set, with both shoes and tires -- than for the concert that is the ostensible reason for their expense. But the fireworks themselves were beautiful and that's what really matters.
I just wish that the resort and Oro Valley Police personnel who were so diligent in directing us into the resort to spend money had spent a little more time planning how to get us out of it afterwards. I kept telling Skylar that we were safe, but, having heard a former colleague's tales of the dangerous beasts that live on Sonoran fairways, I was getting a little anxious during the passage of our dark purgatory. Perhaps that's because the extreme heat had caught up with me. I didn't feel that hot on the grass, despite the 110 degree temperatures when we arrived, but I think that the my body was fooled by the moisture coming off the well-irrigated course. Right now I'd settle for thinking crooked, which would be a big improvement on feeling like a pot roast waiting to be carved.


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Sinaloa Cartel distributor who supplied Crips, Gangster Disciples, Vice Lords for two decades gets 15-year term
A Sinaloa drug cartel distributor was sentenced to 15 years in prison for drugs and gun crimes on December 6. 51-year-old Jesus "Pedro" Raul Salazar-Espinoza of Sinaloa, Mexico, was brought down after a four-year investigation by the Los Angeles Strike Force.
The Los Angeles Strike Force identified Jesus Raul Salazar-Espinoza as a mid-level distributor for the Sinaloa Cartel, who coordinated drug-distribution activities in Mexico, Los Angeles, and throughout the United States. The investigation revealed that Salazar had previously been deported to Mexico multiple times over the years, but had illegally re-entered the U.S. to continue his drug distribution criminal enterprise.
READ: The Real Narcos: Profile of Miguel Ángel Félix Gallardo, Mexico's "El Padrino" of drug lords
Supplying Crips, Gangster Disciples, Vice Lords
Salazar led a Los Angeles-based organization that was fully operational and active for over 20 years. It consistently supplied narcotics, which included cocaine, heroin, fentanyl, methamphetamine and marijuana to major street gangs such as the Compton-based "Santana Blocc" Crips, the Long Beach-based "Insane Crips," the Long Beach-based "Rollin' 20s" Gang, the Mississippi-based Gangster Disciples Gang, and the Mississippi-based Vice Lords Gang and career drug dealers nationwide. The investigation further revealed that Salazar would routinely arrange narcotics deliveries and money pick-ups with his Mexico-based sources in the Sinaloa Cartel.
READ: Sinaloa Cartel hitman extradited to United States
"Mr. Salazar's 15-year prison sentence is a result of the tireless efforts of law enforcement to bring drug traffickers to justice," said United States Attorney Nick Hanna. "This case illustrates that drug traffickers will face severe consequences for spreading poison across American communities."


text:
Posted by: Stenros | August 19, 2009
Ridicule as a Weapon of Choice
The two-year-old story about a clown block making fun of a KKK hate rally is making rounds on the internets. I had not run into this story before. Below is the original news item from Asheville Indymedia (from Wayback Machine).
Knoxville rejects Nazis and Klan.
Saturday May 26th the VNN Vanguard Nazi/KKK group attempted to host a hate rally to try to take advantage of the brutal murder of a white couple for media and recruitment purposes. http://www.volunteertv.com/special
Unfortunately for them the 100th ARA (Anti Racist Action) clown block came and handed them their asses by making them appear like the asses they were.
Alex Linder the founder of VNN and the lead organizer of the rally kicked off events by rushing the clowns in a fit of rage, and was promptly arrested by 4 Knoxville police officers who dropped him to the ground when he resisted and dragged him off past the red shiny shoes of the clowns. http://www.volunteertv.com/home/headlines/7704982.html
"White Power!" the Nazi's shouted, "White Flour?" the clowns yelled back running in circles throwing flour in the air and raising separate letters which spelt "White Flour".
"White Power!" the Nazi's angrily shouted once more, "White flowers?" the clowns cheers and threw white flowers in the air and danced about merrily.
"White Power!" the Nazi's tried once again in a doomed and somewhat funny attempt to clarify their message, "ohhhhhh!" the clowns yelled "Tight Shower!" and held a solar shower in the air and all tried to crowd under to get clean as per the Klan's directions.
At this point several of the Nazi's and Klan members began clutching their hearts as if they were about to have a heart attack. Their beady eyes bulged, and the veins in their tiny narrow foreheads beat in rage. One last time they screamed "White Power!"
The clown women thought they finally understood what the Klan was trying to say. "Ohhhhh…" the women clowns said. "Now we understand…", "WIFE POWER!" they lifted the letters up in the air, grabbed the nearest male clowns and lifted them in their arms and ran about merrily chanting "WIFE POWER! WIFE POWER! WIFE POWER!"
It was at this point that several observers reported seeing several Klan members heads exploding in rage and they stopped trying to explain to the clowns what they wanted.
Apparently the clowns fundamentally misunderstood the nature of the rally, they believed it was a clown rally and came in force to support their pointy hated brethren. To their dismay, despite their best jokes and stunts and pratfalls the Nazis and Klan refused to laugh, and indeed became enraged at the clowns misunderstanding and constant attempts to interpret the clowns instruction.
The clowns on the other hand had a great time and thought the Nazis were the funniest thing they had ever seen and the loud laughter of over 100 counter protesters greeted every attempt of the Nazis and Klan to get their message out, whatever that was.
Many of the local Knoxvillians that came to counter demonstrate had no illusions about why these out of state bad clowns with swastikas were doing in their town.
"KKK YOU CAN'T HIDE, WE CHARGE YOU WITH GENOCIDE!"
"GAY, STRAIGHT, BLACK, WHITE ONE STRUGGLE ONE FIGHT!"
"U.G.L.Y. KLAN YOU AIN'T GOT NO ALIBI, YOU UGLY, YOU UGLY"
Were just a few of the chants that the non clown counter protesters rained down upon the Nazis. The clowns interacted with the non clown protesters with glee and even participated in a chant or two, though apparently with no idea that the Nazis were indeed not clowns thinking it was just part of the show.
In the end the 20 or so sad VNNers left with their tails between their legs. At this point over 150 counter demonstraters were present. The clowns seeing how dejected and sad the Nazi's looked began singing to cheer them up.
"hey hey hey hey, ho ho ho ho—good bye, good bye" everyone sang waving their arms in the air in unison.
After the VNNers left in their shiny SUVs to go back to Alabama and all the other states that they were from the clowns and counter demonstrators began to march out of the area chanting 'WHOSE STREETS? OUR STREETS!"
But the cops stopped the clowns and counter protestors. "Hey, do you want an escort" an African-American police officer on a motorcycle asked. "Yes" a clown replied. "We are walking to Market Square in the center of town to celebrate."
The police officers got in front of the now anti racist parade and blocked the entire road for the march through the heart of Knoxville. An event called imagination station was taking place and over 15,000 thousand students and their parents were in town that weekend. Many of them cheered as the clowns, Knoxvillians and counter protestors marched through the heart of Knoxville singing and laughing at the end of the Nazi's first attempt at having a rally in Knoxville.
On June 16th the Stormfront Nazis are trying to have a second rally in Knoxville. Clowns, anarchist, activist and others are all invited to come and creatively and nonviolently help us confront these Nazis and give them an even bigger counter rally than the first. If you can come, or can help email.
I just love these kinds of groups. Using play and ridicule to combat intolerance has a long history. This reminds me of the time in the 1940's when Stetson Kennedy exposed the secrets of the Ku Klux Klan in a Superman radio show.
In the post-World War II era, the Klan experienced a huge resurgence. Its membership was skyrocketing, and its political influence was increasing, so Kennedy went undercover to infiltrate the group. By regularly attending meetings, he became privy to the organization's secrets. But when he took the information to local authorities, they had little interest in using it. The Klan had become so powerful and intimidating that police were hesitant to build a case against them. Struggling to make use of his findings, Kennedy approached the writers of the Superman radio serial. It was perfect timing. With the war over and the Nazis no longer a threat, the producers were looking for a new villain for Superman to fight. The KKK was a great fit for the role. In a 16-episode series titled "Clan of the Fiery Cross," the writers pitted the Man of Steel against the men in white hoods. As the storyline progressed, the shows exposed many of the KKK's most guarded secrets. By revealing everything from code words to rituals, the program completely stripped the Klan of its mystique. Within two weeks of the broadcast, KKK recruitment was down to zero. And by 1948, people were showing up to Klan rallies just to mock them. (from Mental_floss)
But what happened on June 16th 2007? Is this clown block still in existance? My google-fu is failing me when it comes to Knoxville anti racist action. Anyhoo, I hope that groups like Bounce and ImprovEverywhere feel inspired by this.
Posted in flash mobs, history, inspiration, society
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They didn't come back on June 16th. We ran them out of town. Douchebags.
By: pablo906 on February 21, 2011