text:
using namespace PGA;
using namespace PGA::Operators;
using namespace PGA::Shapes;
using namespace PGA::Parameters;
using namespace PGA::AxiomGenerators;
using namespace PGA::Rendering;

namespace Scene
{
	typedef DynamicRightPrism<Constants::MaxNumSides> DPrism;
	const unsigned int QueueSize = <avgQueueSize>;
	const std::map<std::size_t, std::size_t> GenFuncCounters = <genFuncCounters>;
	const unsigned int NumEdges = <numEdges>;
	const unsigned int NumSubgraphs = <numSubgraphs>;
	const bool Instrumented = <instrumented>;
	const unsigned int MaxNumAxioms = <gridY> * <gridX>;

<code>

	const unsigned int NumPhases = 1;

	struct Controller : Scenes::GriddedScene < <gridY>, <gridX> >
	{
		template <unsigned int AxiomId>
		struct AxiomTraits : Grid::DefaultAxiomTraits < Box, 0 >
		{
			__device__ __inline__ static math::float3 getSize(const Box& shape)
			{
				return math::float3(40.0f, 35.0f, 40.0f);
			}

		};

		typedef Grid::Dynamic<AxiomTraits, 1> AxiomGenerator;

		struct TerminalsTraits
		{
			__host__ __device__ __inline__ static unsigned int getMaxNumVertices(unsigned int terminalIndex)
			{
				return 0;
			}

			__host__ __device__ __inline__ static unsigned int getMaxNumIndices(unsigned int terminalIndex)
			{
				return 0;
			}

			__host__ __device__ __inline__ static unsigned int getMaxNumElements(unsigned int terminalIndex)
			{
				switch (terminalIndex)
				{
				case 0:
					return 80 * MaxNumAxioms;
				case 1:
					return 642 * MaxNumAxioms;
				case 2:
					return 1 * MaxNumAxioms;
				default:
#if (defined(__CUDA_ARCH__) && (__CUDA_ARCH__ > 0))
#if defined(CHECK_INVARIANTS) && (CHECK_INVARIANTS == 2 || CHECK_INVARIANTS == 3)
					printf("TerminalTraits::getMaxNumElements(..): invalid terminal index [terminalIndex=%d] (CUDA thread %d %d)\n", terminalIndex, threadIdx.x, blockIdx.x);
					asm("trap;");
#endif
#else
#if defined(CHECK_INVARIANTS) && (CHECK_INVARIANTS == 1 || CHECK_INVARIANTS == 3)
					throw std::runtime_error(("TerminalTraits::getMaxNumElements(..): invalid terminal index [terminalIndex=" + std::to_string(terminalIndex) + "]").c_str());
#endif
#endif
					return 0;
				}
			}

			__host__ __inline__ static std::unique_ptr<InstanceMesh> createInstanceMesh(unsigned int terminalIndex)
			{
				math::float2 vertices[3] = { { -0.5, -0.5 }, { 0.5, 0 }, { -0.5, 0.5 } };
				switch (terminalIndex)
				{
				case 0:
					return std::unique_ptr<InstanceMesh>(new ShapeMesh<Box>());
				case 1:
					return std::unique_ptr<InstanceMesh>(new ShapeMesh<Quad>());
				case 2:
					return std::unique_ptr<InstanceMesh>(new ShapeMesh<DPrism>(DPrism(vertices, 3)));

				default:
#if defined(CHECK_INVARIANTS) && (CHECK_INVARIANTS == 1 || CHECK_INVARIANTS == 3)
					throw std::runtime_error(("TerminalTraits::createInstanceMesh(..): invalid terminal index [terminalIndex=" + std::to_string(terminalIndex) + "]").c_str());
#endif
					return nullptr;
				}
			}

			__host__ __inline__ static std::unique_ptr<Material> createTriangleMeshMaterial(unsigned int terminalIndex)
			{
				std::unique_ptr<Material> material(new Material(std::unique_ptr<Shaders::ColorShader>(new Shaders::ColorShader())));
				return material;
			}

			__host__ __inline__ static std::unique_ptr<Material> createInstanceMaterial(unsigned int terminalIndex)
			{
				std::unique_ptr<Material> material(new Material(std::unique_ptr<Shaders::ColorShader>(new Shaders::ColorShader())));
				return material;
			}

		};

		static std::string name()
		{
			//return std::string("partition_<idx>_<uid>_") + std::to_string(getNumElements()) + ((<optimized>) ? "_o" : "") + ((Instrumented) ? "_i" : "");
			return std::string("partition_<idx>_") + std::to_string(getNumElements()) + ((<optimized>) ? "_o" : "") + ((Instrumented) ? "_i" : "");
		}

	};

}


text:
Stephen K Amos wants to make you laugh and spread a little peace in the process, one venue at a time
An evening of peace, one venue at a time
Dawn Hinsley
Stephen K Amos wants to be the everyman that brings people together, using the power of comedy
Stephen K Amos is hoping to unite his audiences with the universal language of laughter.
The comedian has announced he is heading back out on the road with Everyman, touring the UK for three months, and bringing the show to Lincoln Performing Arts Centre on Friday, January 31, 2020.
Stephen K Amos is on a mission to bring about world peace. Or to at least bring about an evening of peace, one venue at a time.
In an age when arguments are started over everything from politics to bendy straws, Stephen is attempting to rise above the anger to remind us of what we have in common.
Audiences are told to expect a heartwarming show of funny anecdotes and hilarious takes on the everyday.
Kaiser Chiefs announce new dates on huge UK tour - here's where you can see them
Stephen was recently seen in the three-part series Pilgrimage: The Road to Rome, alongside Katy Brand and Les Dennis.
The BBC Two series, which aired in April and May 2019, saw celebrities give up their creature comforts to follow the Via Francigena trail in France and Italy – to finish up at the Vatican.
Stephen said: "I do jokes, I like to have a laugh and see the good in people.
"Comedy has taken me around the world. I don't walk, I'm not religious. So going on Pilgrimage was a huge personal shift for me. "
Pilgrimage: The Road to Rome - Stephen K Amos meets the Pope (Image: BBC)
"Never in my mind's eye did I think I'd have a private half-hour audience with the Pope. Not to be blessed by the pontiff, but able to ask unedited questions on behalf of millions.
"His response genuinely moved me. Whatever your beliefs are, everyone deserves dignity. If you fail to respect that, then you don't have a human heart."
Show time: 8pm. Tickets: £18 / £15 (students & U26s). Age guide: 16+
Box office: 01522 837600 or online.
Follow Lincolnshire Live What's On
If you want to stay up to date with events, food, nightlife, days out and entertainment news from across Lincolnshire, there's a number of ways you can do it:
Follow our Lincolnshire Live What's on page on facebook - go and give us a like by clicking here.
We've got a dedicated What's On channel on our website - which you can visit by clicking here.
There are also dedicated pages which collate our articles on Food and Drink, Family and Kids, Music and Nightlife, and Shopping.
And if you're looking specifically for family oriented events, or want to share news on a family event you have organised, why not join our Lincolnshire with Kids group on facebook?
Lincoln Performing Arts Centre
Family & KidsThis life-size T Rex is in Lincoln - and it will blow you away!Dinosaur Encounter has arrived at the Collection in Lincoln
EntertainmentHelp Elmer the Patchwork Elephant celebrate his birthday in LincolnElmer is a patchwork of brilliant colours!
EntertainmentOliver! at Lincoln Cathedral has 'broken box office records' - but there are STILL tickets availableA new stage and seating arrangement too
Summer Holidays64 ideas for FREE family events, activities and days out during the summer holidays in LincolnshireDon't let the long holiday be a financial stress
Food & DrinkSubway extend vegan range AND make gluten free introductionFor veggies, vegans, flexitarians or anyone who just fancies a meat-free munch

redpajama_set_name: RedPajamaCommonCrawl


Just 25 meters from the hotel is the Legazpi metro stop, line 3.
Buses which pass through the hotel are: 6, 8, 18, 19, 22, 45, 47, 59, 62, 76, 78, 79, 85, 86, 123, 148, 156, 247, N12, N13 and N14.
Since the M-30 towards Cordoba, take Exit 13, to Legazpi.


text:
Q: Modifying Hyperlink with openxml I'm trying to modify a hyperlink inside a word document.  The hyperlink is originally pointing to a bookmark in a external document.   What I want to do is change it to point to an internal bookmark that as the same Anchor.
Here's the code I use... It seem to work when I what the variables but when I look at the saved document it is exactly like the original.
What is the reason my chances don't persist?
// read file specified in stream
MemoryStream stream = new MemoryStream(File.ReadAllBytes("C:\\TEMPO\\smartbook\\text1.docx"));
WordprocessingDocument doc = WordprocessingDocument.Open(stream, true);

MainDocumentPart mainPart = doc.MainDocumentPart;

// The first hyperlink -- it happens to be the one I want to modify
Hyperlink hLink = mainPart.Document.Body.Descendants<Hyperlink>().FirstOrDefault();
if (hLink != null)
{
    // get hyperlink's relation Id (where path stores)
    string relationId = hLink.Id;
    if (relationId != string.Empty)
    {
        // get current relation
        HyperlinkRelationship hr = mainPart.HyperlinkRelationships.Where(a => a.Id == relationId).FirstOrDefault();
        if (hr != null)
        {
            // remove current relation
            mainPart.DeleteReferenceRelationship(hr);
            // add new relation with relation
            // mainPart.AddHyperlinkRelationship(new Uri("C:\\TEMPO\\smartbook\\test.docx"), false, relationId);
        }
    }

    // change hyperlink attributes
    hLink.DocLocation = "#";
    hLink.Id = "";
    hLink.Anchor = "TEST";
}
// save stream to a new file
File.WriteAllBytes("C:\\TEMPO\\smartbook\\test.docx", stream.ToArray());
doc.Close();

A: You have not yet saved your OpenXmlPackage when you write the stream ...
// types that implement IDisposable are better wrapped in a using statement
using(var stream = new MemoryStream(File.ReadAllBytes(@"C:\TEMPO\smartbook\text1.docx")))
{
   using(var doc = WordprocessingDocument.Open(stream, true))
   {
      // do all your changes
      // call doc.Close because that SAVES your changes to the stream
      doc.Close();
   }
   // save stream to a new file
   File.WriteAllBytes(@"C:\TEMPO\smartbook\test.docx", stream.ToArray());
}

The Close method states explicitly:

Saves and closes the OpenXml package plus all underlying part streams.

You could also set the AutoSave property to true in which case the OpenXMLPackage will be saved when Dispose is called. The using statement I used above would guarantee that that will happen.

redpajama_set_name: RedPajamaStackExchange


text:
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Most cited articles *
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Clinical, immunophenotype and cytogenetic profile of acute lymphoblastic leukemia in children at tertiary health care centre in India
Sirisha Rani Siddaiahgari, MA Awaghad, MS Latha
July-December 2015, 6(2):112-118
Objective: Data on acute lymphoblastic leukemia (ALL) in Indian children being limited, we analyzed the clinical, immunophenotype and cytogenetic profile of ALL in our pediatric patients. Materials and Methods: This was a prospective and retrospective observational study in which data of 103 children with ALL, aged three months to 18 years were analyzed. Results: Definite male preponderance (70.87%) was observed, 58.25% patients were aged between two to five years. Common clinical features included fever (92.33%), pallor (87.38%), hepatomegaly (85.44%) and splenomegaly (83.50). central nervous system involvement was seen in 6.80% and tumor lysis syndrome in 32.04% patients. Hemoglobin was <5 gm/dl in 43.69%, between 5-10 gm/dl in 45.63% patients; white blood cell count between 5,000-50,000/hpf seen in 69.90%, >50,000 in 20.39% patients. Platelet count was <50,000 cells/hpf in 48.54%. Blast cells in peripheral smear present in 67.96% patients of 97 in whom immunophenotyping was done, 82.44% were Pre B cell ALL. Pre T and T cell ALL was seen in 15/97 (15.46%) patients. Karyotyping revealed hyperdiploidy in 9/89, hypodiploidy in 2/89, miscellaneous changes in 35 patients. FISH analysis in 63 patients revealed Philadelphia chromosome positivity in seven (11.11%). MLL gene was positive in 12.70%. TELAML was positive in 13.64% (3/22) patients. 97.06% patients went in to remission post induction. Conclusion: Most of our patients come under standard risk by their age, WBC count, immunophenotyping and cytogentic analysis. We suggest larger multi-centric studies even in developing countries to understand the clinical profile and RT-PCR technique in cytogenic analysis for better risk stratification to help in risk adopted therapy.
Histopathological profile of ovarian tumours: A twelve year institutional experience
Deepti Vijay Mankar, Gaurav K Jain
Context: Ovarian tumours represent about 30% of all cancers of the female genital system. They manifest in a wide spectrum of clinical, morphological and histological features. Aim: To study the frequency of incidence of different histopathological types of ovarian tumours in our institute. Materials and Methods: This retrospective study included 257 cases of histopathologically proven ovarian tumours, reported in the Department of Pathology of a rural tertiary care referral hospital, over a 12 year period (January 2000 to December 2011). These were classified according to the WHO classification of ovarian tumours (2003). Clinical presentation of the patients was analysed from archived case records. Results: Of the 257 tumours studied, 162 (63.04%) were benign, 15 (5.84%) were borderline and 80 (31.12%) were malignant. Surface epithelial tumours were the most common (68.48%) followed by germ cell tumours (15.95%). Mucinous cystadenomas (32.69%) were the most common benign tumours, while serous cystadenocarcinomas (31.13%) were the most common malignant tumours. Most ovarian neoplasms (43.19%) occurred in the 21-40 years age-group. Dull abdominal pain was the most common clinical presentation. Conclusions: Benign ovarian tumours were more common than malignant ones across all age groups. Surface epithelial tumours were the most common histopathological type of ovarian tumour. Due to vague symptoms, patients present late. Development of methods for early diagnosis of ovarian neoplasia is therefore, a pressing need today. The relative frequency of incidence of different ovarian tumours shows regional variations, highlighting the need to identify region-specific risk factors.
Liquid biomedical waste management: An emerging concern for physicians
Sasmita Biswal
July-December 2013, 4(2):99-106
The safe and effective management of health care biomedical waste has received much attention for improper and inadequate management is associated with an increase in the incidence of health risks to the healthcare workers, the patients, and their environment and to the community at large. Hence the development of safe and effective management of biomedical waste along with handling protocols, institutional plans and policies, appropriate training and feedback programs on proper waste management and handling for all the healthcare workers are highly recommended. In India, with the implementation of Biomedical Wastes (Management & Handling) Rules 1998, emphasis is being placed mainly on the proper handling, segregation and disposal of the healthcare waste by which the risks and hazards to an individual and to the community can be considerably reduced. Though a technology and treatment protocol already exists, liquid biomedical waste management still remains a major problem for all healthcare facilities. So proper training in handling of waste will enable the healthcare facility to diffuse this critical problem safely and cost effectively while managing their liquid biomedical waste. So a literature search using the terms liquid biomedical waste was done and this review describes the problems associated with its management.
9 52,245 2,685
A hospital-based study of anti-TPO titer in patients with thyroid disease
E Jacob Jeena, M Malathi, K Sudeep
July-December 2013, 4(2):74-77
Context: Autoimmunity against the thyroid gland is one of the most important causes for thyroid dysfunction. Anti-thyroid antibody test is an important tool in the evaluation of autoimmune thyroid disorders. Aims: To study the prevalence of thyroid hormone dysfunction and positive anti-TPO antibody titers in patients being evaluated for thyroid-related disorders. Settings and Design:This retrospective cross-sectional study was done in Father Muller Medical College. Materials and Methods: The TSH (Thyroid stimulating hormone), FT 4 (Free thyroxine), and anti-TPO titer reports of 74 subjects undergoing evaluation for thyroid-related disorders were analyzed. Statistical Analysis Used: Statistical significance was estimated by P value. Results: About two-third (60%) of hypothyroid patients showed raised TPO antibody titer. The titer was significantly higher in hypothyroid subjects when compared to the euthyroid subjects, and a majority of the hypothyroid subjects had a titer at least twice the upper limit of normal. Two of the three subjects with hyperthyroidism also had elevated anti-TPO titers. Conclusions: The commonest cause of hypothyroidism in our study subjects was autoimmune-related thyroid disease. Anti-TPO antibody estimation is a very useful test for establishing the etiological diagnosis of autoimmune thyroid diseases in our population. In situations where there is a diffuse non-progressive goiter, anti-TPO antibody estimation can substitute for an invasive FNAC.
Detection of Rotavirus and Adenovirus diarrhea in children below five years, in Dakshina Kannada District, a coastal region of Karnataka State, India
Anup Kumar Shetty, Faizan Mohammad Kalekhan, Sibin Jose Muthiravalapil, Rekha Boloor, Beena Antony
Context: Diarrheal disease is the second largest cause of death of children under 5 years. Viral diarrhea is most common which is usually caused by Rotavirus followed by enteric Adenovirus. Rotaviruses are responsible for approximately 527,000 deaths mainly in low-income countries of Africa and Asia. There is limited number of studies done on viral diarrhea in this coastal belt. Aim: To determine the prevalence of Rotavirus and Adenovirus diarrhea among children below 5 years of age and its epidemiological importance in this coastal region of Karnataka State, India. The impact of factors like socio-economic status, drinking water, and Rotavirus immunization status that can contribute to the disease were also evaluated and recommendations are formulated for disease prevention. Materials and Methods: Children below 5 years of age with history of diarrhea, vomiting and fever of less than 3 days were included in this study. The sample size was 35. General physical examination, clinical findings and other details like socio-economic status, personal hygiene, growth milestones and family income were also recorded. A commercial Rotavirus and Adenovirus antigen detection kit was used to detect the presence of Rotavirus and Adenovirus antigen from the stool sample. Results: Out of 35 patients screened, 25 (71.43%) patients were negative for both Adenovirus and Rotavirus, 10 children (28.57%) were positive for Rotavirus and no patients were positive for Adenovirus. Severe dehydration, fever, loose stools and vomiting were the commonest symptoms seen in Rotavirus positive children. The highest incidence of infection with Rotavirus was seen among 7-12 months age group. Children whose stool was positive for Rotavirus used public water supply. Conclusions: Rotavirus is an important cause of diarrhea in children below 5 years in this coastal region. A simple, rapid immunochromatography test is useful and economical tool to simultaneously detect and screen Adenovirus and Rotavirus. Low socioeconomic state and unsafe water supply contributes to diarrheal disease.
Nutritional status and morbidity profile of school-going adolescents in a district of West Bengal
Abantika Bhattacharya, Mausumi Basu, Supantha Chatterjee, Raghu Nath Misra, Gagori Chowdhury
January-June 2015, 6(1):10-15
Background: In India, adolescent age group (10-19 years) constitutes 21.4% of the total population. The health and nutritional status of the adolescents is an index of its future manpower. It is well recognized worldwide that anthropometric measurements are indispensable in diagnosing undernutrition. Objective: To assess the nutritional status and morbidity pattern among school-going adolescents. Materials and Methods: A descriptive cross-sectional study was carried out in three randomly selected co-educational schools of Burdwan District of West Bengal in May 2013 among 424 adolescents in the age group of 10-19 years from class V to class XI (except class X), using a predesigned pretested proforma. Results: The prevalence of underweight and stunting were 53.31% and 47.41%, respectively, which was significantly higher in early adolescence than in late adolescence and more in boys than in girls. About 55.18% had pallor, 40.33% had dental caries, 33.49% were suffering from refractive errors, 23.11% had history of worm infestation, 38.90% had skin problems, and 68.61% adolescents had ENT problems. Conclusion: The health and nutritional status among the school-going adolescents was found to be poor.
Necessity of detection of extended spectrum beta-lactamase, AmpC and metallo-beta-lactamases in Gram-negative bacteria isolated from clinical specimens
Mehvash Haider, Meher Rizvi, Nazish Fatima, Indu Shukla, Abida Malik
Background: With increasing incidence of resistance to antibiotics carbapenems are used as the last resort because they are stable even in response to extended spectrum and AmpC beta-lactamases. However, Gram-negative bacilli producing the acquired metallo-beta-lactamases (MBL) are on the rise. Aim: The aim of the following study is to detect phenotypically the presence of extended spectrum beta-lactamase (ESBL), AmpC and MBL in Gram-negative bacteria isolated from clinical specimen. Materials and Methods: Gram-negative isolates from clinical samples were screened and confirmed for the presence of ESBLs by double disk synergy test (DDST), for AmpC by disk approximation assay and for MBL by Modified Hodge Test and imipenem-ethylenediaminetetraacetic acid DDST. Results: Among 251 isolates studied, 138 (54.98%) were ESBL producers, 49 (19.52%) were AmpC producers and 45 (17.93%) were MBL producers. Highest rates of ESBL detection was by Cefoperazone sulbactam (109/138) 78.98%. Out of 92 of the AmpC producing strains 20 (21.73%) were inducible and 72 were stably derepressed (78.26%). Out of 251 strains studied 45 (17.93%) were phenotypically identified as MBL producers, the highest no. being of Pseudomonas aeruginosa. Among the methods employed for detection of MBL production, Hodge test (62.22%) proved better than DDST (40%). Conclusions: High level of antibiotic resistance pattern exists in various clinical isolates. ESBL production should be looked for routinely in Gram-negative bacteria other than Escherichia coli and Klebsiella. A high percentage of derepressed AmpC mutants are noteworthy and alarming. We recommend phenotypic identification methods as routine practice in laboratories as genotypic methods are not cost-effective.
Psoriasis can markedly impair the quality of life of patients irrespective of severity: Results of a hospital-based cross-sectional study
Ajith Vettuparambil, Neelakandhan Asokan, Beena Narayanan
Background and Objectives: There are conflicting opinions in previous studies whether the quality of life (QoL) of patients with psoriasis is affected by its severity. The aim of the study was to assess the QoL of patients with psoriasis attending a tertiary care teaching hospital in central Kerala, India; and to find out if severity of psoriasis as measured by psoriasis area severity index (PASI) affects the QoL. Materials and Methods: We did a cross-sectional study of 49 patients with psoriasis. QoL was assessed using the Malayalam version of the Dermatology Life Quality Index (DLQI). PASI was used to calculate the clinical severity of the disease. We calculated Spearman's rank correlation coefficient between these two scores. Results: Thirty-three (67.3%) patients had marked (moderate or above) impact on overall QoL. Among the various domains of the QoL, symptoms and feeling were found to be affected most, followed by work and school and daily activities. There was no significant correlation between PASI and the overall DLQI (Spearman r = 0.131, P = 0.37), though the domain of leisure activities showed moderately significant positive correlation (Spearman r = 0.037; P = 0.03) with PASI. Conclusion: Psoriasis markedly affects the QoL of the sufferers, especially in the domains of symptoms and feeling, work, and school as well as daily activities. This study does not provide evidence that impairment of QoL is related to severity of psoriasis.
A case of subacute thyroiditis in a patient on adalimumab for treatment of refractory palmo-plantar psoriasis
Anca Chiriac, Liliana Foia, Anca E Chiriac, Vlad E Gorduza, Caius Solovan, Piotr Brzezinski
Recent reports indicate different side-effects of the new medication for psoriasis. Adalimumab. Adalimumab is a biologic agent acting as tumor necrosis factor alpha inhibitor. It is wildly used in treating psoriasis, following a national guide treatment. We report a clinical case of subacute thyroiditis induced by adalimumab in a psoriatic patient. A 54-year-old Caucasian female addressed to our dermatology clinic in 2008 with a 3 years history of moderate to severe psoriasis. The patient had been experiencing non-disabling joint pain in both knees and wrists for several years. Her medical history was remarkable for pulmonary sarcoidosis (at the age of 32), arterial hypertension and angina pectoris. The patient was started on adalimumab 40 mg twice monthly with good clinical evolution, but she was diagnosed, a few months after starting the therapy, with subacute thyroiditis with severe evolution, with transitory hyperthyroidism (thyroid stimulating hormone 0.1 uIU/ml). The treatment with adalimumab was discontinued, the symptoms cleared in 3 weeks with non-steroidal anti-inflammatory drugs and a fully recovered thyroid status was obtained in 1 month. The patient continued the psoriatic medication (adalimumab) with no influence on thyroid status. We describe a case of subacute thyroiditis in a psoriatic patient treated with adalimumab, with a very good clinical evolution with non-steroidal anti-inflammatory medication. Liaison between dermatologists and in this case, endocrinologists and rheumatologists, will help to determine the prevalence of these reactions and to provide insights into the very complex mechanisms of both diseases.
MEDICAL HISTORY PAGE
Discovery of artemisinin: The Chinese wonder drug
Padmaja Udaykumar
Artemisinin, a great boon to the patients of multidrug-resistant malaria, has an equally amazing history. Although used by the Chinese herbal healers centuries ago, its introduction to the modern system of medicine was preceded by extensive research. The success of 'project 523' is further evidence to the medical fraternity that collaborative research can yield rich dividends. Although many claim credit, Dr. Youyou Tu was awarded the Lasker prize for the feat.
Seroprevalence of Transfusion Transmissible Infections (TTIs) among blood donors in a tertiary care hospital, central India: A prospective study
Alok Kumar, Shatish M Sharma, Narayan S Ingole, Nitin Gangane
Background: Blood transfusion having some risks of transfusion transmissible infections (TTIs) in the recipients especially when blood is collected during window period. In Africa, about 10-15% of human immunodeficiency virus (HIV) transmission had been related to blood transfusions. Aims: The aim of this study is to present the prevalence of TTIs among the apparently healthy donors, both voluntary as well as replacement donors. Settings and Design: This was a prospective study, carried out in a blood bank attached to a tertiary care hospital, Central India. Materials and Methods: All blood bags collected from these blood donors during the study period were screened for TTIs like hepatitis B surface antigen (HBsAg; Hepalisa, J. Mitra), anti-HIV antibodies (HIV Ab; HIV 3rd generation kit for detection of antibodies to HIV1 and HIV2, J. Mitra), anti-hepatitis C virus antibodies (HCV Ab; MicroELISA 3rd generation, J. Mitra), and Venereal Diseases Research Laboratory (VDRL) reactivity (Carbogen kit, Tulip Diagnostics). Serum were separated from all blood bags and serological test was performed according to the instructions provided by the manufacturers of respective kit. All seroreactive blood bags were considered as positive for TTIs and the blood bags were discarded. Statistical Analysis: A total of 10,582 blood donors were selected for blood donation after clinical history and brief medical examination by medical officer. Blood bags collected from them were screened for TTIs. Among the total blood bags screened, 273 (2.57%) were found positive for transfusion transmissible infectious diseases. Results: Among TTIs, the most common infection was hepatitis B followed by HIV infection in our study. Prevalence of coinfection in our study was very low (0.01%). Voluntary donations have low seroreactivity (2.40%) for TTIs as compared to replacement donations (3.20%). Conclusions: Multiple infections have a very small but definite risk to the recipients, recieving blood and blood products. Hepatitis B was the most common infection in our study. The incidence of coinfection was very low in our study. Prevalence of TTIs was more among replacement donors as compared to the voluntary donors. So, it is possible to improve the safety of blood and blood product by the promotion of voluntary donation, selection of low-risk donors, and use of highly sensitive laboratory screening test.
4 4,889 1,056
Study of cognitive functions in breast cancer patients: A case control study
Anupama Zeena Sequeira, K Krishnamurthy
Context: One-third of breast cancer survivors report difficulties with concentration, multi-tasking, and memory. Cognitive dysfunction can have an impact on quality of life by affecting activities of daily living, treatment compliance, interpersonal relationships, work/profession, and future. Aims: The objective of this study was to evaluate the cognitive functions in breast cancer patients. Settings and Design: This study was conducted in the outpatient department of Oncology from where the cases were recruited. The controls were patients attending other departments and not suffering from cancer. Materials and Methods: A total of 60 patients, 30 breast cancer patients and 30 non-cancer individuals patients matched for age, education were evaluated. Tools used were SMMSE, TMT-B, and DSST for evaluation of cognitive functions. Statistical Analysis: The various findings were analyzed using Chi-square test, Mann-Whitney Test, T test and ANOVA. Results: Breast cancer patients had highly statistically significant cognitive deficits in language and recall domains and significant deficit on orientation domain of SMMSE. They performed poorly in TMT-B, taking more time to complete the test which was statistically highly significant. No significant deficits were noted on the DSST test. Conclusion: Breast cancer patients show statistically significant cognitive deficits as compared to non cancer individuals.
Healing effect of phenytoin on excisional wound in experimental albino rats
Mohua Sengupta, Prithwijit Banerjee, Suhrita Paul, Janmejoy Sengupta, Mainak Ghosh
Background and Objective: A common side effect with phenytoin is gingival hyperplasia. This apparent stimulatory effect of phenytoin on connective tissue suggested the possibility for its use in wound healing. This study aims to evaluate the effect of 1% and 2% phenytoin ointment on the excisional wound healing process in experimental albino rats, in comparison to 5% betadine ointment. Materials and Methods: Albino rats of Wistar strain (150200 g) were divided randomly into four groups (n = 6). The animals were anesthetized with ether, shaved on the back, and the skin was disinfected using cotton and alcohol wipes. Excisional round, full-thickness skin wounds of diameter 15 mm were created in the paravertebral area, at 5 mm from the midline on the back of all the animals, using sterile disposable acuderm biopsy needle. The following medications were applied topically to the wound twice daily for a maximum of 20 days. Group A rats served as negative control (untreated). Group B rats were applied 5% betadine ointment (positive control). Group C and group D rats had 1% and 2% phenytoin powder applied on them, respectively. Wound healing was measured on days 0, 4, 8, 12, 16, and 20 of the experiment. Number of days taken for complete epithelization of wound was also noted. Statistical analysis was done using analysis of variance (ANOVA) followed by TukeyKramer test and P < 0.05 was considered significant. Results: Both 1% and 2% phenytoin powder hastened healing and reduced the time taken for complete epithelization of excisional wound in albino rats, when compared to negative control (P < 0.05). While 2% phenytoin powder was superior (P < 0.05) to both 1% phenytoin powder and 5% betadine, the latter two were comparable (P > 0.05). Conclusion: 2% phenytoin may be considered as an important agent for wound healing, but its role in the healing of infected wound needs to be explored further.
A study to assess the awareness regarding occupational health hazards among the employees in the laundry department of a selected hospital
Merlin Manuel, Lourdes Daphnie, Sweta D'cunha, Sucharitha Suresh
Background: The importance of a clean environment and linen for optimal patient care has been stressed upon since the very inception of hospitals. Individuals who work in a laundry are required to be adequately informed about the physical and health hazards present in the laundry, the known risks, and what to do if an accident occurs. Every laundry worker must be trained to know the location and proper use of the available personal protective clothing and equipment. Therefore, safe environment in the laundry is essential to maintain their health, and awareness programs should be conducted. Objective of the Study: To assess the awareness regarding occupational health hazards among the employees in the Laundry Department. Materials and Methods: The research method adopted in this study is of a descriptive type. The study was conducted in the Laundry Department of the selected hospital. The sample consisted of 15 respondents. All the employees in the department were included. The tools used to collect the data were an informal interview and the check-list and observation methods. The collected data was analyzed by percentage. Result: The study reveals that a majority of the respondents were knowledgeable about the occupational health hazards and safety measures. However, very few of them were aware of the types of occupational hazards. Conclusion: Awareness of occupational health and safety among the employees is important in the laundry area; therefore, planned orientation, training programs, and proper guidance to the employees will help reduce any kind of danger involved in the job and adoption of the necessary safety measures.
A study on detection of extended-spectrum beta-lactamases (ESBLs) and comparison of various phenotypic methods of AmpC detection in Pseudomonas aeruginosa from various clinical isolates in a tertiary care teaching hospital
Subbalakshmi Easwaran, Ranjani Chittur Yerat, Rajendran Ramaswamy
Introduction: Pseudomonas aeruginosa is one of the major etiological agents of nosocomial infection. They are difficult to treat as the majority of them exhibit varying degrees of innate resistance. Acquired resistance is mediated by the production of chromosomal and plasmid-mediated AmpC beta-lactamases, extended-spectrum beta-lactamases (ESBLs), and metallo-beta-lactamases (MBLs). Objectives: This study was conducted for the detection of ESBLs and the comparison of various phenotypic methods of AmpC beta-lactamases (both inducible and plasmid-mediated) from various clinical isolates of Pseudomonas aeruginosa. Materials and Methods: A prospective study was conducted for a period of 6 months from January 2014 to June 2014. Isolates of Pseudomonas aeruginosa were tested for ESBLs by combined disk diffusion method using ceftazidime/ceftazidime+clavulanic acid (CAZ+CAC). Inducible AmpC beta-lactamases were detected by both ceftazidime-imipenem antagonism test (CIAT) and cefotaxime/cefoxitin (CTX/CX) inducible disk diffusion test. Plasmid-mediated AmpC were detected using AmpC disk test and ethylenediaminetetraacetic acid (EDTA) disk test. All the isolates were tested for cefepime resistance. Results: Out of 116 Pseudomonas aeruginosa isolates, 70 were ceftazidime-resistant. While ESBLs were observed in 67 out of 70 isolates, 36 were positive for inducible AmpC by both the methods. Plasmid-mediated AmpC were detected in only 8 isolates. All the 70 strains showed resistance to cefepime. Conclusions: High prevalence of ESBL and chromosomal-mediated AmpC was observed in Pseudomonas aeruginosa. Both the inducible disk diffusion tests (CIAT, CTX/CX) were equally effective in the detection of inducible AmpC. As Pseudomonas is one of the major nosocomial pathogens, such high resistance poses a grave threat.
Photodynamic therapy: Truly a marriage between a drug and a light
Harveen Singh, Heena Khurana, Harshneet Singh, Manmohit Singh
Microbial biofilms in the oral cavity are involved in the etiology of various oral conditions, including caries, periodontal and endodontic diseases, oral malodor, denture stomatitis, candidiasis and dental implant failures. It is generally recognized that the growth of bacteria in biofilms imparts a substantial decrease in susceptibility to antimicrobial agents compared with cultures grown in suspension. It is therefore not surprising that bacteria growing in dental plaque, a naturally occurring biofilm, show increased resistance to antimicrobial agents. As result there is pronounced interest and keenness in the development of alternate antimicrobial concepts. Therefore, the application of alternative method to eradicate bacteria from periodontal pockets is desirable. One such approach is photodynamic therapy (PDT). The purpose of this review was to evaluate the effectiveness of PDT for periodontitis as an adjunct to non-surgical treatment of scaling and root planning. This review provides an overview of PDT with emphasis on its current status as an antimicrobial therapy to control oral bacteria. Finally, new frontiers of antimicrobial PDT research will be introduced, including targeting strategies that may open new opportunities for the maintenance of bacterial homeostasis in dental plaque, thereby providing the opportunity for more effective disease prevention and control. Thus, the available knowledge of PDT should encourage a more clinically oriented application of this technique.
The study of obesity among children aged 5-18 years in Jaipur, Rajasthan
Anjali Jain, Ashish Jain, JP Pankaj, BN Sharma, A Paliwal
Background: Prevalence of TV and computers in today's times has also driven the regular outdoor activities of children out from their lives. An increased calorie intake along with a decreased physical activity level has a great bearing on the level of obesity found in children. The present study was done with the objective to study the obesity among children of aged 5-18 years in Jaipur, Rajasthan. Methods: A Cross sectional study was undertaken on children of 5-18 years of urban field practice area, Mahatma Gandhi Medical College and Hospital, Jaipur. Simple random sampling was done. A semi-structured questionnaire was developed, pilot study was carried out to draw the necessary questionnaire which was tested and retested for necessary modifications. Body Mass Index (BMI) 10 was derived by dividing the subject's mass by the square of his or her height, Statistical test was applied in our study accordingly. Results: 12.5% children were overweight having percentage between 85 to 95, while only 5.6% children were obese having percentage equal or greater than 95. Out of 564 boys 101 (17.9%) were obese or over-weight and out of 436 boys 69 (15.9%) were obese or over-weight. Among 783 vegetarian children, 14.8% were obese and overweight. Conclusions: Children eating more frequent junk foods were more obese and overweight as comparative eating them in low frequency. Children with lesser physical activity were more obese.
A unique case of substance abuse
K Krishnamurthy, Wilona J Braganza
The desire to periodically alter consciousness by using psychoactive substances is an innate drive similar to hunger, thirst or sex. WHO has defined various substances, psychoactive or otherwise which may potentially be abused. An innovative method of intake was observed while evaluating a patient under our care. An 18-year-old boy was brought for consultation with a history of multiple substance use and anti-social personality traits. On interviewing, patient reported of the use of a white powder in the form of a snake bite. Patient described the technique of the snake bite and his experience following the bite. There have been two previous reports of patients resorting to snake bites for recreational purposes and this unique and extreme mode of undergoing a psychoactive experience needs to be studied further.
Medical comorbidity in in-patients with psychiatric disorder
Christy Maria Manuel, Pavithra P Rao, Preethi Rebello, AT Safeekh, P John Mathai
Objective: To study the prevalence of concurrent medical comorbidity in patients admitted with psychiatric disorders. Materials and Methods: One hundred patients with psychiatric disorders admitted to the general wards of the Department of Psychiatry, Father Muller Medical College, Mangalore were assessed for evidence of concurrent medical comorbidity. The assessment included clinical examination and investigations. Results: 49% of in-patients with psychiatric disorders had medical comorbidity. 26% of patients with bipolar disorder, 13% of patients with schizophrenia and 8% of patients with depressive disorders had medical comorbidity. Diabetes mellitus, hypothyroidism, and hypertension were the most common medical comorbidity. The medical comorbidity was not related to any of the socio-demographic variables. The medical comorbidity was not related to the clinical variables such as duration, age of onset of the psychiatric disorders. The medical comorbidity was significantly more in patients with bipolar mood disorder. Conclusions: 49% of in-patients with psychiatric disorders have concurrent medical comorbidity. Diabetes mellitus is the most common medical comorbidity. The present investigation is an observational, descriptive, cross-sectional clinical study. It has certain merits and limitations. Future studies with more refined methodology are required to draw definite conclusions.
Prevalence of Anemia among rural population living in and around of rural health and training center, Ratua Village of Madhya Pradesh
Sanjay Kumar Gupta, Sanjay S Agarwal, Rituja Kaushal, Ambuj Jain, Vineet Kumar Gupta, Neeraj Khare
Introduction: Nutritional anaemia is a worldwide problem with the highest prevalence in developing countries. It is found especially among women of child-bearing age, young children and during pregnancy and lactation. It is estimated to affect nearly two-thirds of pregnant and one-half of non pregnant women in developing countries. Objectives: To study the trend and severity of anaemia among people attending at Ratua RHTC and various socio demographic factors for the same. Materials and Methods: Hospital based cross sectional study. Observation: The trend of anaemia from 2008 to 2011 was in increasing trend, 9%, 15%, 22%, and 27% respectively and in 2012 constant around 26%. Anaemia was more common in females than males, 18% males and 82% females were reported anaemia of various degrees in the study period. Anaemia was highest among 11-25 years of age 42% followed by 26-40 years 23% and lowest among 0-10 years of age 8.69%. Anaemia among elderly was quite higher 15.5%. Most of the males had mild anaemia 16% followed by moderate 6.61% and severe 0.77% in contrast most of the females had moderate anaemia 42% followed by mild 31.35% and severe 3%. Trend of anaemia in female patients were in increasing trend from 2008-2009, than little decreases in 2010 and further decreases in 2011 after that again increases in 2012. Conclusion: Anaemia was significantly higher in females in comparison to males in moderate and severe category. Anaemia was highest among 11-25 years of age group.
A clinicopathologic study of various breast lesions with cytohistological correlation
Monika Rathi, Mohammad Khalid, Satish Kumar Budania, Ankur Mittal, Nidhi Verma
Context: Most of the females suffer from breast diseases during their life at some time or the other. Confirmation of breast diseases by clinical examination and pathological confirmation by fine needle aspiration cytology (FNAC) and histopathologic examination has been found to be an important part of diagnostic workup in breast diseases. Aims: To establish a clinicopathologic correlation in patients suffering from breast diseases. Settings and Design: We conducted a prospective study from December 2008 to August 2010. One hundred and twenty-one cases were enrolled using simple random sampling methods. Materials and Methods: Data including age, complaints, and clinical examination was collected from patients presenting for FNAC with breast complaints. Results: A total of 128 cases were studied which included 101 benign cases, 21 malignant cases, and 6 inadequate cases. The final 122 cases included 3 (2.5%) cases of acute mastitis, 2 cases (1.6%) of tubercular mastitis, 44 cases (36.1%) of fibroadenoma, 42 cases (34.4%) of benign breast disease with non-specific descriptive diagnosis, 2 cases (1.6%) of fibrocystic disease, 3 cases (2.5%) of galactocele, 1 (0.9%) case of lactational adenoma, 2 cases (1.6%) of cellular fibroadenoma, and 2 cases (1.6%) of phyllodes tumor. Apart from this, there were 21 cases (17.21%) of ductal carcinoma. Majority of benign cases were between 30 and 39 years of age (43.6%). Majority of malignant cases fell between 50 and 59 years of age (47.6%). Majority (61.5%) of lumps (>3 cm) were malignant, whereas 94.8% of lumps (<3 cm) were benign. Left breast was commonly involved (49.18%) than the right breast (44.26%). Superolateral quadrant (63.1%) was the most commonly involved quadrant. Histology was available for 35 benign cases (34.65%) and out of total malignant cases (21), histology was available for 14 cases (66.66%). No discrepancy was noted.
Establishing the reference change values (RCVs) and validating the delta check auto-verification in a clinical biochemistry laboratory
Denver Clive Fernandez, SS Avinash, M Malathi, AR Shivashankara, Arun Kumar, Pearl Andrea Fernandez
Aims: Establishing the reference change values (RCVs) and validating the delta check auto-verification in the hospital information system (HIS). Materials and Methods: This study was conducted in the Hospital Laboratory-Biochemistry. Fifty-one parameters were analyzed in three phases. Phase I: Delta check reference change values were established. Phase II: Delta check auto-verification was validated in the hospital information system. Phase III: Calculation of test requiring manual verification, true and false positive rates. Results: Out of all the test results, 1.35% failed the RCV-delta check thus requiring manual verification, and the remaining 98.65% were auto-verified. Only 0.12% test results were true positives indicating laboratory error, and 1.23% were false positives and were correlated clinically. Ten percent simulated data results and 0.37% actual patient results were not identified by the newly introduced HIS. Conclusions: RCV-delta check is a refined form of the delta checks used to analyze acceptable analytical and biological variation in laboratories. Majority of tests passed the RCV-delta check auto-verification, implying that very few test reports require manual verification. True positives can be detected in the laboratory. All HISs should be validated before implementing complete auto-verification.
Prevalence and risk factors associated with underweight among under-five children in a rural area of Puducherry
Jomon Mathew John, Jomol Sara John
January-June 2018, 9(1):7-11
Background: Nutrition has been recognized as a basic pillar for social and economic development. One in every three malnourished children in the world lives in India. The objective of this study was to measure the prevalence and to study the selected factors associated with underweight among the under-five children in a rural area of Puducherry. Aims: This study aims to study the prevalence of underweight among children under-five years of age and to study the associated risk factors. Methodology: This was a cross-sectional study conducted over a period of 13 months with a sample size of 500. The anthropometric assessments were taken and plotted on the Indian Academy of Pediatrics growth charts.Results: The prevalence of underweight was found to be 23.8%. The age of the child, gender, socioeconomic status, duration of exclusive breast feeds, birth order, and birth weight were found to have statistical significance in underweight. However, the maternal education did not show any significance in underweight. Conclusion: Nutritional status of under-five years children is one of the important indicators of overall development of community and thus country. Intervention to reduce the burden of underweight should be directed toward the education of the mothers regarding the importance of nutrition by community health workers.
Seronegativity HBsAg, HCV and HIV among blood donors: A five year study
Om Bodarya, Atul V Shrivastav, Ukti Bhavsar, Ashok Ramanuj, Jayesh R Joshi, Ashok S Agnihotri
Introduction: This study is conducted to evaluate the seroprevalance of HIV, HBsAG, HBV and syphilis among blood donors at blood bank of medical college hospital along the five years. Material and methods: Study includes both voluntary and replacement donors. HIV, HBsAG and HCV were tested by ELISA methods approved by NACO and RPR was carried out for screening of Syphilis. Results: The seroprevalance of HIV, HBsAG, HCV and Syphilis was 0.08%, 0.3%, 0.07% and 0.17% respectively in voluntary blood donors while seroprevalance of HIV, HBsAG , HCV and Syphilis was 0.31%, 1.18%, 0.16% and 1.12% respectively in replacement blood donors. Conclusion: We observe that seroprevalance is higher in replacement donors than voluntary donors. These facts strongly indicate that we need more motivational and educational programmes to shift complete voluntary donation.
Spectrum of complications in sinusitis
Mahesh Bhat, Vinay Vaidyanathan, S Vishak, George Pinto
Complications of paranasal sinus infection most often involve the orbit and peri-orbita. Because of widespread use of antibiotics, intracranial extension of paranasal sinusitis is rarely seen today. Nevertheless, the clinician must be aware of the potential of these complications as late recognition of this condition and delay in treatment can increase morbidity and mortality rates. An interesting case of sinusitis with orbital and intracranial complication is presented, which was radiologically evaluated and was comprehensively managed. Unparallel role of radiological investigations cannot be over emphasized as it played a very important role in both assessment and timing of the surgical intervention. The key to successful treatment is aggressive management and timely surgical intervention. We have extensively reviewed literature and comprehensively discussed pathophysiology and radiological assessment of such cases.
* Source: CrossRef


It is a huge area and relates to almost everything our eyes can watch or can't watch. The mind can philosophize about doing it. It can talk about it.
may be verified by new observations. The solution to this is apparently leaning strongly toward the thought that there is not just a single universe that could be created, but there are a broad range of fundamental theories (or unique variants of the identical theory, dependent on different physical parameters, original energy states, etc) and our universe is merely one of these probable universes. It's left from the normal model.
Reservations aren't required for refreshments. 1 choice eradicates the rest of the alternatives. Only your personal experience is logical!
Stephen Hawking, among the best theoretical physicists, has died at his house in Cambridge. Witten began to work on the very first string theory revolution in 1984, which dealt with the issue of gravitational anomaly. He is quickly recognized because he is censored.
of the distinguished names in particle physics (or might not have heard about) are people that are renowned for work from 30-50 years back. There are not any renowned physicists. The aforementioned observation is the result of the Casimir effect.
That turtle stands on the rear of a third turtle and so forth. The mind can philosophize about doing it. It can talk about it.
Only then can humanity decide if they are ready to create the commitment. Attempting to comprehend the way the universe works is the largest mystery that man can solve. But we know that we have to take care of our boys.
General relativity, for example, produces remarkable insights into the basis of spacetime. A physicist doesn't get medals. He does not get recognition or prizes.
learn how to provide value to the end-user, irrespective of industry.
So, as you may have seen, a poll on who is the best physicist has been running on our site for more or less a month. My aim is to give an overall idea of how sociologist obtain and assess information regarding human societies. Academic promotion is dependent upon your research achievements.
It's also vitally important that those who will devote the majority of their productive years attempting to work on an idea have faith it is going to pan out. Don't hesitate to post in the comments any doubts you've got and I won't be afraid to address them. That debate will go on.
Research and teaching work in theoretical physics demand a doctorate in the area. In reality, the principles were taught to each young scientist for nearly 200 decades. If it is completely consistent with the theory it's supported.
The parameters are absolutely free to take on several values and the laws to have any form that causes a self-consistent mathematical theory, and they do take on various values and various forms in various universes. Operational variables are amazingly unique to the extent they are occasionally measured and reported without misinterpretation. Unfortunately, it comes with a lot of strings attached.
The remaining portion of the world is going to do the job, of attempting to shoot you down, for you. The straightforward actuality that life on every continent is presently distinct is another sort of evidence. As this moment you're not an island.
Theoretical Physicist Definition: the Ultimate Convenience!
Among the most profound advances in science in the past several years is the way researchers from a variety of fields are beginning to consider consciousness. If you consider the psychology of science, nobody likes change. His most renowned work, Principia, is among the most essential scientific books ever written.
Meditation itself doesn't require any methods or techniques whatsoever. Studying physics can permit you to develop a variety of skills that could be applied in many locations, both scientific and non-technical. It depends crucially on its theories because they are the things that give it is predictive power.
Stephen Hawking, among the best theoretical physicists, has died at his house in Cambridge. A physicist doesn't get medals. He does not drink champagne.
The standard of a physical theory is also judged on its capacity to create new predictions which may be verified by new observations. Specifically, it provides a theoretical framework to create deterministic equations of motion, for bodies that are under influence of forces. A role model will be able to help you lay out a career path that's realistic and practical.
Ph.D. programs in theoretical physics can be finished in 4-6 decades. It's still a fact that science can inform you how something works but never why. When there's a specific physics topic you're interested in knowing more about, have a look through our Topics section.
Most of the distinguished names in particle physics (or might not have heard about) are people that are renowned for work from 30-50 years back. Shockingly, in some specific instances, theorists have discovered that these two very different theories are in fact secretly the exact same, Headrick states. And that sort of interplay of not having the ability to even grasp the notion of a 3 dimensional universe is quite pertinent to theoretical physics and lots of theoretical physicists nowadays are citing Edwin Abbott's work in the 19th century.


Florida Coastal Faculty of Law is a fully accredited law school whose culturally diverse students graduate observe-ready by exhausting work and award-successful, ongoing sensible coaching that is taught by supportive and experienced full-time faculty. Law is a system of guidelines that are created and enforced via social or governmental institutions to manage behavior 2 It has been defined each as "the Science of Justice" and "the Art of Justice". For the reason that law organizes justice, the socialists ask why the law should not also organize labor, training, and religion.
Many cities or counties have public libraries accessible, as do law schools. Maryland exempts the sale of tangible personal property that's manufactured for the purpose of initiating, supporting or sustaining breastfeeding from the sales and use tax. The law can be an instrument of equalization only because it takes from some persons and provides to different individuals.
Recognized as a "Best Worth Law Faculty" by Nationwide Jurist for the past four years, NIU Law gives an unbeatable combination of high quality schooling, glorious outcomes, and affordable prices. If a person endeavours to obtain a repeal of these laws, that are conceived to be obnoxious, or the introduction of any laws which he believes to be salutary, if he does that legally, there is no such thing as a objection to it.
The Common Declaration of Human Rights acknowledges that 'if man is not to be compelled to have recourse, as a final resort, to rebellion towards tyranny and oppression', human rights must be protected by the rule of law. There is no justice in following unjust laws.
If this nation should ever reach the purpose where any man or group of men by drive or menace of drive could long defy the instructions of our courtroom and our Constitution, then no law would stand free from doubt, no judge would make sure of his writ, and no citizen could be protected from his neighbors.


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Dr Nandam - Cancellation Policy
Patients who attend a Telehealth Appointment with Dr Lawrence Sanjay Nandam will be bulk billed the appointment fee with no out-of-pocket expense. If a patient is unable to attend their appointment, they need to cancel directly with Dr Nandam's office via telephone, email or SMS no later than 24 hours before the scheduled appointment. Cancellations and rescheduled appointments made with more than 24 hours notice will attract no financial penalty.
If a patient cancels their appointment after confirmation has been received and under 24 hours before the appointment time, a cancellation fee of $192.65 will be charged directly to the patient. Cancellation fees will be issued on a 7 day payable invoice. No Medicare rebate is applicable to the cancellation fee. No further appointments will be scheduled until the cancellation fee is paid in full.
Patients are advised of our cancellation policy when called with their appointment details. A text message is sent to all patients with a working mobile phone number with the appointment details which includes information of the cancellation policy. Our system allows us to confirm if and when text messages are read, to confirm the patient has received the notification.
Dr Nandam's process for confirming appointments is to contact all patients the business day prior to the appointment. If the patient is not contactable, we hold the right to reschedule the appointment to a later time and date. Every effort will be made to contact both the patient and/or their next of kin. Every effort is made to keep the patient up to date and reminded of their appointment.
Cancellation fees are charged as we are not always able to fill the cancelled appointment. The fee is comprised of the minimum consultation fee of $142.65 plus a $50 administration charge. Dr Nandam's office reserve the right to waive the cancellation fee in certain circumstances. Dr Nandam's office will advise the referring medical practice and doctor if a cancellation fee has been charged to their patient.
How is the Cancellation Fee charged?
The cancellation fee will be issued to the patient via an invoice, payable in full within 7 days.
How do I pay the invoice?
Payment can be made via electronic funds transfer (EFT), directly into the bank account, details of which are on the invoice.
What do I do if I can't afford the cancellation fee?
In certain circumstances, a payment arrangement will be made to allow the patient a longer period to pay off their cancellation fee. All arrangements can be made directly with Dr Nandam's office.
Can I get a medicare rebate on the cancellation policy?
No medicare rebates are available for cancellation fees.
Can I reschedule my appointment?
Appointments will only be rescheduled once the cancellation fee is paid in full.
What if missing my appointment was unavoidable?
Call the team at Dr Nandam's office to discuss further.
Dr L S Nandam, Consultant Psychiatrist. Provider No: 239225MK
Ph: 07 5429 8480 E: drnandamsoffice@gmail.com
A: Suite 375, Level 1, 241 Adelaide Street, Brisbane Q 4000
Association Solutions, Suite 375, Level 1, 241 Adelaide Street, Brisbane Q 4000, Australia+617 5429 8480info@associationsolutions.com.au


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Beans, Meats, Soups, Meals, Tuna, and Peanut Butter!!
For those who attended the May 8th meeting at Harvesters, those 6 foods have great meaning. For 90 minutes we helped sort the "proteins" for Harvesters. Whether it was by the pound or by the count, we completed several pallets of food that will be sent out to area food pantries. In addition to the IIE members, this was an excellent opportunity for a few of the kids to help out as well. Working the tape gun was my son's favorite part, but whether it was taping boxes, sorting foods, counting or weighing cans, they definitely we able to lend a hand.
The final 30 minutes included an informative tour of the volunteer sort area, storage warehouse, and both the refrigerated and freezer warehouses. It's very interesting to see the various ways the food arrives to the warehouse, is handled, and then distributed to those who need it most. Thanks to all those attending!


Pioneer Park is located on Route 30 at the far west end of the village, adjacent to the Hinckley-Big Rock Elementary School is a nostalgic village park. The open space and large shade trees make this a perfect place to visit often whether for a play date, picnic, group outing, or for just a quiet get-a-way. Tennis court, shelter, play area.


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Home / Entertainment / Billie Shepherd Wants More Kids Next Year
Billie Shepherd Wants More Kids Next Year
By Stephen on December 24, 2020
The former 'TOWIE' star already has Nelly, six, and three-year-old Arthur with her husband Greg, and she hopes to have another child next year after she finishes competing in 'Dancing On Ice'.
She said: "I'd really like to have more children, but towards the end of next year maybe.
"Nelly's like, 'I only want a sister Mummy'. So I'm like 'I can't really guarantee that for you.' And she's like, 'Imagine if we had another Arthur'.
"I said, 'Don't be so mean'. She wants her little dolly. When I asked Arthur, he said he wants a sister but he just copies everything Nelly says."
Although she wants more kids, Billie admitted she does suffer "mum guilt" as she tries to juggle work and motherhood.
She said: "It's a real juggling act – there are a million and one things going on. I'm trying to skate as early as possible so I've got my days freed up."
And the star feels lucky she has Greg and her mum around.
She added to OK! magazine: "After Christmas it's going to be getting really intense with the 'Dancing On Ice' training and the live shows.
"I always try to keep my weekends free for the children but with the live shows you're committed to the weekends.
"I'm really lucky I've got Greg, my mum and family around. The kids won't notice as much but I'll feel the mum guilt.
"No one's perfect. I'm not the perfect mum. When 'The Mummy Diaries' is on air, we get so much support and lovely comments but what I've found is that mums and parents love to see the raw stuff, kids having tantrums, me having a go at Greg, because that's real life."
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At least 10 rebel fighters are believed to have been killed, following a suicide bombing, at a border post, in Syria.
The Britain-based Syrian Observatory for Human Rights said a suicide bomber struck a bus transporting fighters through the Atmeh border post, one of several crossings Syrian rebels use to bring in fighters and supplies.
The monitoring group said the attack killed 10 fighters.
A local activist in the province said the blast killed 40 people. The activist said some 200 rebels from various factions are based near Atmeh, and bring in weapons through the crossing.


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text:
! { dg-do compile }
! { dg-options "-fdump-tree-original" }
!
! PR fortran/34848
!
! The "0" for the string size of the absent optional
! argument was missing.
!
module krmod
contains
 subroutine doit()
   implicit none
    real :: doit1
    doit1 = tm_doit()
   return
 end subroutine doit
 function tm_doit(genloc)
   implicit none
   character, optional  :: genloc
   real :: tm_doit
   tm_doit = 42.0
 end function tm_doit
end module krmod

! { dg-final { scan-tree-dump " tm_doit \\(0B, 0\\);" "original" } }
! { dg-final { cleanup-tree-dump "original" } }
! { dg-final { cleanup-modules "krmod" } }

redpajama_set_name: RedPajamaGithub