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text:
There's Nothing You Can Do About Your Student Loans
by Phil Stott | November 09, 2015
Just in case you needed any more proof that we're not likely to see a sudden U-turn from the government over the ability to clear student loans in bankruptcy, Bloomberg has another story on the subject for us today—this time detailing the lengths that Uncle Sam will go to in order to ensure that your loan will not be dischargeable in bankruptcy.
The piece focuses on the case of on Tangerie Shells, a social worker with an elderly mother disabled husband, and three children to support. Having already filed for bankruptcy, Shells is attempting to have her $137,000 in loans forgiven "because paying them, she said, would make it impossible to provide for five family members."
Like the case of Robert Murphy I highlighted recently (also written by Bloomberg's Natalie Kitroeff, who is carving a unique niche with her reporting in this area), this is a case that seems open and shut on first glance, but that quickly becomes more complicated the deeper you delve.
Unlike Murphy's case, which hinges to a large extent that he borrowed the money towards the end of his career to pay for his children's education—an act that some have interpreted as a deliberate attempt to circumvent the system—Shells' case is really about the detail. Like, all the way down to her daily spending habits, and whether they constitute a "normal" amount of spending.
Witness: Department of Education attorneys raised objections to Shells' $700-per-month food budget, noting that some of it was spent on meals outside the home. And her $567 monthly car payment was also viewed as excessive—her protestations about needing a larger vehicle to meet the needs of her extensive family notwithstanding.
This, then, is the state of the student loan market today—a place where loan obligations are extremely hard to get rid of, and where scrutiny of even the smallest details of your life will be necessary if you are to achieve such a thing.
Unfortunately, there's not a huge amount of advice out there for people who are already struggling with their payments—other than to try to find a way to make a few. If nothing else, doing so will establish that you've made a good faith effort to pay them—a factor that is weighed as part of the process when deciding if you qualify for a write-off.
For those who are at the beginning of their college careers, however, it's important to know that the decisions you're making right now could have an effect that will last for the rest of your life. That shouldn't be a reason to back out of getting a higher education—it's still the best thing you can do for your lifetime earnings potential—but it does mean that you should think carefully about the sticker price of the institution you're considering, and whether it's truly worth it.
Is the Student Loan System on the Brink of Destruction?
Millennials: The Best Thing You Can Do For Your Career
Attention Millennials: The Most Important Thing You Can Do For Your Career
Filed Under: CSR|Education|Salary & Benefits

redpajama_set_name: RedPajamaCommonCrawl


text:
saint martha catholic church wedding music
Instrumental [I] and Vocal [V] Music
Choose 3-4 to be played before the wedding. 1-2 may be vocal solos. Choose 1 for the Seating of the Family
I-1. Air from Suite in D (Bach)
I-2. Arioso (Bach)
V-3. Ave Maria - Schubert
V-4. Be Thou My Vision - Irish Folksong
I-5. Be Thou With Me (Bist du bei mir – Bach)
I-6. Canon in D - Pachelbel
I-7. Hornpipe, Air & Trumpet Tune from Water Music Suite (Handel)
V-8. How Beautiful - Paris
I-9. Jesu, Joy of Man's Desiring (Bach) (most often selected for Seating of the Family)
I-10. Movement I from Concerto in Bb (Handel)
I-11. Movement I from Concerto in F (Handel)
I-12. My Shepherd Will Supply My Need (American Folk Melody)
V-12. My Shepherd Will Supply My Need
I-13. Sheep May Safely Graze (Bach)
V-14. Panis Angelicus - Franck
V-15. Prayer of Saint Francis of Assisi - Dunlap
V-16. The Gift of Love - Hopson
I-17. The Entrance of the Queen of Sheba (Handel)
I-18. Trumpet Tune in C Major (Manfredini)
I-19. Trumpet Tune in D Major (Antonio Vivaldi)
I-20. Trumpet Tune in D Major (Telemann)
I-21. Voluntary in A Major (Wesley)
I-22. Wachet auf, ruf' uns die Stimme (Wake, Awake, for Night is Flying – Bach)
Processionals of the Bridesmaids and Bride.
Choose one for each
P-1. Rigaudon (Andre Campra)
P-2. Rondeau (Jean Mouret)
P-3. Te Deum (Charpentier)
P-4. Trumpet Tune in C Major (Henry Purcell)
P-5. Trumpet Voluntary in D Major-Clarke
P-6. Trumpet Voluntary in D Major (John Stanley)
Entrance Antiphon
Choose one.
E-1. "And I saw the holy city…coming down from God, prepared as a bride adorned for her husband. Alleluia (Rev. 12:2)
E-2. "Christ loved the Church and handed Himself…to present her as a holy and spotless bride for Himself. Alleluia (Eph. 5)
E-3. "For as a young man marries a young woman, so shall your…God rejoice over you. Alleluia." (Isaiah 62:5)
E-4. "I give you a new commandment, that you love one another as I have loved you…Alleluia." (John 13: 34)
E-5. "May the God of Israel join you together, and may He be with you. Alleluia." (Tob.7:15, 8:19)
E-6. "May the Lord send you help from the holy place…Alleluia." (Psalm 19:3-5)
The Responsorial Psalm
R-1. Psalm 33: "The earth is full of the goodness of the Lord" (Psalms in His Presence)
R-2. Psalm 34: "Taste and See" (Haugen
R-3. Psalm 128: "Blest Are Those Who Love You"
R-4. Psalm 145: "I Will Praise Your Name"
R-5. Psalm 148: "Let all praise the name of the Lord"
The Gospel Acclamation (Alleluia Verse)
Choose one
G-1. Everyone who loves is begotten of God and knows God.
G-2. God is love. Let us love one another, as God has loved us.
G-3. If we love one another, God remains in us, and His love is brought to perfection by us.
G-4. May the Lord bless you from Zion, He who made both heaven and earth.
G-5. Whoever remains in love, remains in God, and God in him.
 G-6. Cantor's Choice
Offertory and Communion
Choose one for the Offertory and one for the Communion.
O-1. Adoro Te Devote (Gregorian Chant) [Instrumental]
O-2. Love Divine, All Love's Excelling
O-3. The King of Love, My Shepherd Is
O-4. What Wondrous Love
O-5. Where True Love and Charity Are Found (Ubi Caritas)
O-6. Within Your House, O God, Today
Recessional Of The Wedding Party
X-1. Hornpipe and Trumpet Tune from the Water Music Suite (Handel)
X-2. La Majesté (from The Heroic Music – Telemann)
X-3. Ode to Joy (Beethoven)
X-4. Psalm XIX (Benedetto Marcello)
X-5. Rejoicing, Bourée, and Minuet from the Royal Fireworks Suite (G. F. Handel)
X-6. Toccata from Symphony V (Widor)
X-7. Trumpet Tune in C Major (Manfredini)
X-8. Trumpet Tune in D Major (Purcell)
X-9. Trumpet Tune in D Major (Vivaldi)
X-10. Trumpet Voluntary in C (Purcell)


text:
Q: Usage of sending curve from fundamental group to the endpoint of its lift? Let $p: \bar{X} \rightarrow X$ be a covering space projection. Let $[f] \in \pi_{1}(X, x_{0})$. We can define the following map
$r: \pi_{1}(X, x_{0}) \rightarrow p^{-1}(x_{0})$
$r[f] = \bar{f}(1)$ where $\bar{f}: [0,1] \rightarrow \bar{X}$ is the unique lift of f, a loop in $X$.
This map provides an pretty clear isomorphism between $\pi_{1}(S^{1})$ and $\Bbb{Z}$. Moreover, we can prove some properties about this map, such as it being surjective if $\bar{X}$ is path connected, and being bijective if $\bar{X}$ is simply connected. It seems like this could be a helpful tool in calculating other fundamental groups—is that the case? Here is another example:
Example: We have the the quotient map for $\frac{S^n}{\sim}$ where $\sim$ identifies antipodal points is also a covering space map. $\frac{S^{n}}{\sim}$ is $\Bbb{RP}^{n}$, so our covering map looks like $p: S^{n} \rightarrow \Bbb{RP}^{n}$ with $p^{-1}(x_{0})$ having exactly 2 elements (that is how we identified them). Since $S^n$ is simply connected, we have that the map $r$ defined above is bijective. There is a unique group structure on 2 elements, so $\pi_{1}(\Bbb{RP}^{n}, x_{0}) = \Bbb{Z}_{2}$.

A: In deed it is sometimes useful to use the Galois correspondence for fundamental groups. It roughly says:
If $p\colon (\tilde X,\tilde x_0)\to (X,x_0)$ is the universal covering, then there is an isomorphism between the fundamental group and the group of deck transformations $\pi_1(X,x_0)\to Aut(p)$.
A deck transformation of $p\colon (\tilde X,\tilde x_0)\to (X,x_0)$ is a homeomorphism $f\colon \tilde X\to\tilde X$, s.t. $p \circ f = p$. The set of all deck transformations of $p$ is called group of deck transformations $Aut(p)$. A covering space $(\tilde X, \tilde x_0)$ is called universal covering space, if it is a path-connected and simply-connected space.
The Galois correspondence says more:
There  is  a  correspondance  between  conjugacy  classes  of  subgroups  of
$\pi_1(X,x_0)$ and  coverings  of $X$ without basepoints up to iso. We always need spaces, which are path-connected, locally path-connected and semi-locally simply connected. For more information just search for Galois correspondance and fundamental groups.
In my opinion a more powerful tool to just calculate something is the theorem of Seifert-van Kampen.

redpajama_set_name: RedPajamaStackExchange


text:
/**
 * Unit tests for the ImageProfilesHelper object.
 */
"use strict";

// Require the super classes for this class.
const UnitTest = require("./base.unit.js");
const ImageProfilesUnitTest = require("./imageProfiles.unit.js");
const BaseHelperUnit = require("./base.helper.unit.js");

// Require the local module being tested.
const restApi = require(UnitTest.API_PATH + "lib/imageProfilesREST.js").instance;
const fsApi = require(UnitTest.API_PATH + "lib/imageProfilesFS.js").instance;
const helper = require(UnitTest.API_PATH + "imageProfilesHelper.js").instance;
const path1 = ImageProfilesUnitTest.VALID_IMAGE_PROFILES_DIRECTORY + ImageProfilesUnitTest.VALID_IMAGE_PROFILE_1;
const path2 = ImageProfilesUnitTest.VALID_IMAGE_PROFILES_DIRECTORY + ImageProfilesUnitTest.VALID_IMAGE_PROFILE_2;
const badPath = ImageProfilesUnitTest.INVALID_IMAGE_PROFILES_DIRECTORY + ImageProfilesUnitTest.INVALID_IMAGE_PROFILE_BAD_NAME;

class ImageProfilesHelperUnitTest extends BaseHelperUnit {
    constructor() {
        super();
    }
    run(){
        super.run(restApi, fsApi,helper,  path1, path2, badPath );
    }
    runAdditionalTests (restApi, fsApi, helper, path1, path2, badPath) {
        this.testCompare(restApi, fsApi, helper, UnitTest.API_PATH + UnitTest.COMPARE_RESOURCES_DIRECTORY_1, UnitTest.API_PATH + UnitTest.COMPARE_RESOURCES_DIRECTORY_2);
    }
}

module.exports = ImageProfilesHelperUnitTest;

redpajama_set_name: RedPajamaGithub


How to fix the infamous Nook Color / Nook Tablet charging USB cable for good?
The Barnes&Noble Nook Color / Nook Tablet have a proprietary micro USB charging port which is longer than normal and allows power charging with 2Amps.
The charging/data cable from BN is infamous to break after some time, most probably the cable's primary plastic coating is not very flexible and starts to split at the point where it enters the micro usb connector and leads to a visible secondary shielding. If nothing is done the situation worsens and in the end the internal power cables may short.
I got my used B&N Nook Color with a beginning coating split and cannot get a replacement from B&N because I live outside the US and have no invoice.
Seems like this problem is a common one, there are already discussions about a class action lawsuit.
What can I do besides looking for a replacement?
I fixed the cable early before it was too late.
The problem zone is the hard transition from the connector to the cable. Shear force due to moving/bending the cable is very strong there when the cable is inserted into the Nook. This is the place where it starts to break and that needs to be fixed.
Add another coating to this transition to reduce shear force.
Like the other answer, I too re-inforced a NEW cable, as a pre-emptive measure.
I experimented a little with the heat shrink tubing and superglue method, but supergluing the smaller heat shrink tube (which has to be slit in order to put on the cable) is messy, and prone to failure after applying the necessary heat to shrink it tight on the cable.
Wrap the tape tightly around the cable itself, on the area closest to the connector, until it is the same diameter as that first (round) stage of the connector. Cut the tape.
Next wrap more tape over that area, close as possible to the larger (square) part of the connector, so that it covers both the previous tape wrap plus the smaller round (flange) part of the connector. Wrap tightly until it is about level or possibly a little higher than the square part of the connector. Cut the tape.
Next wrap more tape around that last wrap of tape plus part of the square connector, say with the edge right at the "n" LED, with about 3 turns maximum. Cut the tape. All done.
Advantages to this method include NOT subjecting the cable end to heat high enough to shrink the heat tubing (and possibly causing other damage). Also you don't need any other equipment or materials besides 3/4" electrical tape and scissors. Wrapping in 3 separate "level" sections keeps the tape from wrinkling, and if wrapped tightly, looks quite neat when done.
RECOMMENDATION: Wrap in the SAME DIRECTION for each of the 3 sections, and cut the tape such that tape sections end on the opposite side of the connector's "n" LED.
I'd like to add a fun alternative: use some Sugru. It's a flexible silicone rubber which can stick to just about anything and is simply moulded by hand. It air cures to a tough durable rubber. This is a UK invention (I'm sure they now have it in the US), so might be an alternative for us over here.
I wasn't smart enough to be preemptive, though I had plenty of warning as the intermittent problem became more frequent and finally failed completely (no wiggling the cord would make it work).
So, I opened up the connector on the Nook end (with the "N") and reconnected with solder the two broken leads. This was tricky since the circuit board there is only about 5/16 inch square! There are four conductors: red, green, black and white insulation colors in the cord. Both the black and the white leads were broken off.
After testing and reassembly, I wrapped the area with black, stretchy electricians tape to provide better strain relief at that vulnerable site.
My problem is not in the cable but in the nook. Looking inside the plug port it appeared at first that some of the male pins were bent, then in time just not there. I called the help line and they said it was non repairable. And of course would give me credited on a new nook. Which amounted to more than just going to Amazon and buying one.
Not the answer you're looking for? Browse other questions tagged hardware nook-color or ask your own question.
Is there any good micro USB cable (not loose)?
How to change default PDF viewer on Nook Color?
Gingerbread ROM for Nook Color?
What is the difference between running/installing cm7 off SD and EMMC for Nook Color?
Can I use an Android OS card on the new Nook Tablet?
How can I load a Video Player App on my Nook Color without google play?


text:
Cocaine: how "mules" are spotted in Guyana
Speech in Strasbourg: Emmanuel Macron wraps himself in "the rule of law"
Worldline: TCG Companies goes below 5% of the capital
Worldline: TCG Companies drops below 5% of capital
L'Oréal: signs an exclusive partnership with Verily – 2022-01-20 at 18:15
Jean-Luc Mélenchon sentenced for public insult and defamation against Radio France
Héloïse Goy with Alexis Patri
10:23 a.m., January 12, 2022
In 2018, after the publication by Radio France of an investigation suspecting overbilling during the presidential campaign of candidate Jean-Luc Mélenchon, the latter attacked journalists from Franceinfo. Justice has just condemned the member of France Insoumise to a fine and damages.
"Assholes", "liars", "cheaters". It is with a chosen vocabulary that the tribune of France Insoumise had qualified in 2018 the journalists of Franceinfo in a video. Jean-Luc Mélenchon had also invited his supporters to "rot them wherever they could". This video followed an investigation published by the investigation unit of Radio France. This investigation suspected overbilling during the candidate's presidential campaign in 2017.
3,000 euros in damages
The investigation was relayed by Franceinfo and Jean-Luc Mélenchon then reacted in a video posted on his Facebook account. He also accused Franceinfo of being a state radio station that obeyed the executive. Following this video Radio France had lodged a complaint.
The Paris Criminal Court has just ruled: the deputy for rebellious France is sentenced to a fine of 500 euros suspended for public insult and defamation. He will also have to pay 3,000 euros in damages to Radio France. Jean-Luc Mélenchon's lawyer announced that his client would appeal this decision.
Tagged defamationFranceinsultJeanLucMélenchonpublicradiosentenced


text:
Der U-Bahnhof Majdan Nesaleschnosti (, ) ist ein U-Bahnhof der Metro Kiew am Majdan Nesaleschnosti, dem zentralen Platz der ukrainischen Hauptstadt Kiew.

Daten
Der U-Bahnhof besteht aus einer zentralen Halle mit Säulengängen und einem Bahnsteig von 102 m Länge und 16 m Breite. Er ist täglich von 5.40 Uhr bis 00.14 Uhr geöffnet und wird zur Hauptverkehrszeit im 90-Sekunden-Takt von den Zügen angefahren.

Der Bahnhof liegt in 102 m Tiefe unter Grund an der U-Bahn-Linie 2 (Kureniwsko – Tscherwonoarmijska) zwischen den U-Bahnhöfen Postplatz () und Lew-Tolstoi-Platz (). Er hat ein Personenverkehrsaufkommen von täglich 39.600 (2011) Personen.

Geschichte
Der Bahnhof wurde am 17. Dezember 1976 als U-Bahnhof "Kalininplatz" eröffnet, kurz danach, mit Umbenennung des Platzes, in U-Bahnhof "Platz der Oktoberrevolution" umbenannt und trägt seit 1991 seinen heutigen Namen. Vom 18. bis 24. Februar 2014 war der U-Bahnhof auf Grund der Unruhen des Euromaidan geschlossen.

Anbindung
Am U-Bahnhof besteht eine Umsteigemöglichkeit zur U1 am U-Bahnhof Chreschtschatyk.

Weblinks

 Inoffizielle Seite des U-Bahnhofs (russisch)
 Seite des U-Bahnhofs auf Kiew-Enzyklopädie (ukrainisch)

Einzelnachweise

Majdan Nesaleschnosti
Majdan Nesaleschnosti
Majdan Nesaleschnosti
Erbaut in den 1970er Jahren
Chreschtschatyk (Kiew)

redpajama_set_name: RedPajamaWikipedia


text:
Photo by Joan Marcus.
Even in 2018, the term "gold digger" generally connotes laziness, dishonesty, and fraud.
Skintight:
"Gold Diggers" Frauds or Icons?
by Roundabout Theatre
Upon learning that Elliot's new partner is a 20-year-old named Trey, Jodi and Benjamin immediately mistrust his motives. Trey swears that he loves Elliot regardless of their difference in age, but Jodi and Benjamin are convinced that Trey is only after Elliot for his money and lavish gifts. Trey's role in this play may seem familiar -- his storyline draws from the archetype of the Gold Digger, traditionally portrayed in literature, film, and music as a young woman who dates or marries rich men for their money alone. As a young man rather than a young woman, Trey is an inversion of the traditional type, but the implications of calling him a gold digger remain much the same. The term is used colloquially today in a generally derogatory manner against those who are seen as dating only for mercenary purposes, but the history of the phrase has more folds than one might think.
Jack Wetherall and Will Brittain as Elliot and Trey in "Skintight"
Joan Marcus
The phrase "gold digger" was popularized by Avery Hopwood's play The Gold Diggers, which premiered at the Lyceum Theatre on Broadway in 1919 and depicted the young women of its story as sly and cunning seductresses of rich men. Though Hopwood's gold diggers often outwitted their male counterparts, their ultimate motives didn't get much more complex than a superficial hunger for wealth and luxury. The play, though itself relatively sympathetic toward its gold digger characters, spawned a decade of storylines that portrayed gold diggers as unscrupulous pleasure-seekers who needed to be reformed into demure housewives. In the early 1930s, though, the gold diggers of film and theatre became the heroines of stories in which they deftly outsmarted rich businessmen, whom the nation had come to villainize with the advent of the Great Depression. Audiences cheered actresses such as Joan Blondell, Ginger Rogers, and Mae West, whose characters, struggling through poverty, gamed an unjust system in pursuit of basic necessities and respect.
In the second half of the 1930s, Hollywood tightened enforcement of its Motion Picture Production Code, which set the standards for what could and could not be shown on film. Heightened censorship led filmmakers to revert back to storylines in which gold-digging women who broke the "moral code" were punished rather than glorified. With some exceptions, the films of the late 1930s largely condemned gold diggers -- an attitude that pervaded American culture and even led some cities to adopt actual laws prohibiting gold-digging behavior.
Left to right: Joan Blondell in "Back in Circulation" (1937), Ginger Rogers in "Having a Wonderful Time" (1938), and Mae West in "My Little Chikadee" (1940)
In the decades since Hollywood's Depression-era censorship code, the gold digger icon never regained the heroism of those early-1930s mavericks. From hit movies like Gentlemen Prefer Blondes (1953) and Some Like It Hot (1959) to top songs like "Lyin' Eyes" by The Eagles (1975) and "Gold Digger" by Kanye West (2005), the gold digger archetype has been portrayed only occasionally with sympathy and depth and almost never again as a street-smart rebel who emerges victorious over the upper class.
Even in 2018, the term "gold digger" generally connotes laziness, dishonesty, and fraud. But the origins of the trope reveal that there may be more to unpack from these characters than cultural assumptions might have us believe. Calling Trey a gold digger, then, might be a more complicated label than it seems.
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Designing Skintight
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Ron Vlaar is the name Villa Park will be willing the stadium announcer to read out when Villa's team is revealed tonight.
Vlaar is battling to be fit to face Arsenal after succumbing once again to a persistent calf problem.
The 28-year-old captain had not returned to training on Friday after limping out of action in the win at Sunderland.
Boss Paul Lambert admitted it might be "needs must" when asked if Vlaar could be rushed back into action.
Villa's recent record without the Dutch defender confirms how important he has become for the claret and blues.
After he limped off midway through the win at Southampton, Villa went five games without a win, with four straight defeats and a draw.
On his return they won and kept a clean sheet at Sunderland before exiting the FA Cup to lower-league Sheffield United without him last weekend.
Without Vlaar, Villa could have a central defensive crisis. Nathan Baker hurt his hamstring in the warm-up last weekend.
Baker had not trained by Friday and, like Vlaar, was due to have his progress assessed yesterday. Matt Lowton could continue to cover alongside Ciaran Clark in central defence, while youngster Janoi Donacien has been on the bench for the past two matches.
Gabby Agbonlahor and Brad Guzan are expected to start tonight after being rested for the cup defeat.
Joe Bennett resumed training with the group for the first time since October this weekend, while Chris Herd (hamstring) has started light jogging.


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Gierlinski, Marek
Data Analyst, Computational Biology
Wnt regulates amino-acid transporter Slc7a5 and so constrains the integrated stress response in mouse embryos
Poncet, N., Halley, P., Lipina, C., Gierlinski, M., Dady, A., Singer, G., Febrer, M., Shi, Y-B., Yamaguchi, T. P., Taylor, P. & Storey, K., 7 Jan 2020, In : EMBO Reports. 21, 1, p. 1-20 20 p., e48469.
Amino Acid Transport Systems
Embryonic Structures
Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice
Nanda, S. K., Petrova, T., Marchesi, F., Gierlinski, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P. & Arthur, J. S. C., 1 Dec 2019, In : Life Science Alliance. 2, 6, p. 1-19 19 p., e201900533.
EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis
Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.
How well do RNA-Seq differential gene expression tools perform in a complex eukaryote? A case study in A. thaliana
Froussios, K., Schurch, N., Mackinnon, K., Gierlinski, M., Duc, C., Simpson, G. & Barton, G., 6 Feb 2019, In : Bioinformatics.
Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis
Eykelenboom, J., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T., 6 May 2019, In : Journal of Cell Biology. 218, 5, p. 1531-1552 22 p.
Chromatids
G2 Phase
Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages
Guo, M., Härtlova, A., Gierlinski, M., Prescott, A., Castellvi, J., Hernandez Losa, J., Petersen, S. K., Wenzel, U. A., Dill, B., Emmerich, C. H., Ramon Y Cajal, S., Russell, D. G. & Trost, M., 3 Jun 2019, In : EMBO Journal. 38, 11, p. 1-15 15 p., e100299.
Scavenger Receptors
In vitro reconstitution of kinetochore–microtubule interface reveals a fundamental error correction mechanism
Doodhi, H., Kasciukovic, T., Gierlinski, M., Li, S., Clayton, L. & Tanaka, T. U., 29 Oct 2018, In : BioRxiv. 31 p.
Kinetochores
Aurora Kinase B
Spindle Poles
Live-cell imaging of marked chromosome regions reveals dynamics of mitotic chromosome resolution and compaction
Eykelenboom, J. K., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T. U., 17 May 2018, In : BioRxiv. 53 p.
Genomic Instability
Neural differentiation, selection and transcriptomic profiling of human neuromesodermal progenitor-like cells in vitro
Verrier, L., Davidson, L., Gierlinski, M., Dady, A. & Storey, K., 12 Jul 2018, In : Development. 145, 16, 10 p., dev166215.
Clustered Regularly Interspaced Short Palindromic Repeats
Proteome-wide analysis of protein abundance and turnover remodelling during oncogenic transformation of human breast epithelial cells
Ly, T., Endo, A., Brenes, A., Gierlinski, M., Afzal, V., Pawellek, A. & Lamond, A. I., 2 May 2018, In : Wellcome Open Research. 3, p. 1-48 48 p., 51.
Proteus: an R package for downstream analysis of MaxQuant output
Gierlinski, M., Gastaldello, F., Cole, C. & Barton, G., 20 Sep 2018, In : BioRxiv. 10 p.
Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib
Miettinen, T. P., Peltier, J., Härtlova, A., Gierliński, M., Jansen, V. M., Trost, M. & Björklund, M., 15 May 2018, In : EMBO Journal. 37, 10, p. 1-19 19 p., e98359.
Proteasome Endopeptidase Complex
Mechanisms mitigating problems with multiple kinetochores on one microtubule in early mitosis
Yue, Z., Komoto, S., Gierlinski, M., Pasquali, D., Kitamura, E. & Tanaka, T. U., 15 Jul 2017, In : Journal of Cell Science. 130, 14, p. 2266-2276 11 p.
Molecular mechanisms facilitating the initial kinetochore encounter with spindle microtubules
Vasileva, V., Gierlinski, M., Yue, Z., O'Reilly, N., Kitamura, E. & Tanaka, T. U., 26 Apr 2017, In : Journal of Cell Biology. 216, 6, p. 1809-1822 14 p.
Saccharomycetales
High resolution imaging reveals heterogeneity in chromatin states between cells that is not inherited through cell division
Dickerson, D., Gierlinski, M., Singh, V., Kitamura, E., Ball, G., Tanaka, T. U. & Owen-Hughes, T., 8 Sep 2016, In : BMC Cell Biology. 17, 16 p., 33.
Correlation between the photon index and X-ray luminosity of black hole X-ray binaries and active galactic nuclei: Observations and interpretation
Yang, Q. X., Xie, F. G., Yuan, F., Zdziarski, A. A., Gierliński, M., Ho, L. C. & Yu, Z., 21 Feb 2015, In : Monthly Notices of the Royal Astronomical Society. 447, 2, p. 1692-1704 13 p.
active galactic nuclei
High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow-derived macrophages
Guo, M., Härtlova, A., Dill, B. D., Prescott, A. R., Gierliński, M. & Trost, M., Sep 2015, In : Proteomics. 15, 18, p. 3169-3174 6 p.
Phagosomes
Phagocytosis
Quantitative proteome analysis of temporally-resolved phagosomes following uptake via key phagocytic receptors
Dill, B., Gierliński, M., Härtlova, A., González Arandilla, A., Guo, M., Clarke, R. G. & Trost, M., 1 May 2015, In : Molecular & Cellular Proteomics. 14, 5, p. 1334 1349 p., 16.
Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment
Gierlinski, M., Cole, C., Schofield, P., Schurch, N. J., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G., Owen-Hughes, T., Blaxter, M. & Barton, G. J., 15 Nov 2015, In : Bioinformatics. 31, 22, p. 3625-3630 6 p.
Evaluation of the diagnostic accuracy of prototype rapid tests for human African trypanosomiasis
Sternberg, J. M., Gierlinski, M., Biéler, S., Ferguson, M. A. J. & Ndung'u, J. M., Dec 2014, In : PLoS Neglected Tropical Diseases. 8, 12, p. e3373 8 p.
Routine Diagnostic Tests
Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment
Natsume, T., Müller, C. A., Katou, Y., Retkute, R., Gierlinski, M., Araki, H., Blow, J. J., Shirahige, K., Nieduszynski, C. A. & Tanaka, T. U., 6 Jun 2013, In : Molecular Cell. 50, 5, p. 661-674 14 p.
Stochastic association of neighboring replicons creates replication factories in budding yeast
Saner, N., Karschau, J., Natsume, T., Gierlinski, M., Retkute, R., Hawkins, M., Nieduszynski, C. A., Blow, J. J., de Moura, A. P. S. & Tanaka, T. U., 2013, In : Journal of Cell Biology. 202, 7, p. 1001-1012 12 p.
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects
Saunders, S. P., Goh, C. S. M., Brown, S. J., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W. & 14 others, Madhok, V. B., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.
A quantitative spatial proteomics analysis of proteome turnover in human cells
Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3, M111.011429.
Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation
Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J. & Chubb, J. R., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7350-7355 6 p.
Kinetochore-Dependent Microtubule Rescue Ensures Their Efficient and Sustained Interactions in Early Mitosis
Gandhi, S. R., Gierlinski, M., Mino, A., Tanaka, K., Kitamura, E., Clayton, L. & Tanaka, T. U., 15 Nov 2011, In : Developmental Cell. 21, 5, p. 920-933 14 p.
Simulated spectral states of active galactic nuclei and observational predictions
Sobolewska, M. A., Siemiginowska, A. & Gierliński, M., 11 May 2011, In : Monthly Notices of the Royal Astronomical Society. 413, 3, p. 2259-2268 10 p.
Compton scattering as the explanation of the peculiar X-ray properties of Cyg X-3
Zdziarski, A. A., Misra, R. & Gierliński, M., 21 Feb 2010, In : Monthly Notices of the Royal Astronomical Society. 402, 2, p. 767-775 9 p.
energy spectra
High-resolution whole-genome sequencing reveals that specific Chromatin Domains from most human chromosomes associate with nucleoli
van Koningsbruggen, S., Gierlinski, M., Schofield, P., Martin, D., Barton, G. J., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I., 1 Nov 2010, In : Molecular Biology of the Cell. 21, 21, p. 3735-3748 14 p.
RE J1034+396: the origin of the soft X-ray excess and quasi-periodic oscillation
Middleton, M., Done, C., Ward, M., Gierliński, M. & Schurch, N., 21 Mar 2009, In : Monthly Notices of the Royal Astronomical Society. 394, 1, p. 250-260 11 p.
Reprocessing of X-rays in the outer accretion disc of the black hole binary XTE J1817-330
Gierliński, M., Done, C. & Page, K., 21 Jan 2009, In : Monthly Notices of the Royal Astronomical Society. 392, 3, p. 1106-1114 9 p.
accretion disks
broadband data
What can we learn about quasars from αOX measurements in Galactic black hole binaries?
Sobolewska, M. A., Gierliński, M. & Siemiginowska, A., 11 Apr 2009, In : Monthly Notices of the Royal Astronomical Society. 394, 3, p. 1640-1648 9 p.
quasars
A periodicity of ∼1 hour in X-ray emission from the active galaxy RE J1034+396
Gierliński, M., Middleton, M., Ward, M. & Done, C., 18 Sep 2008, In : Nature. 455, 7211, p. 369-371 3 p.
active galaxies
periodic variations
High-frequency X-ray variability as a mass estimator of stellar and supermassive black holes
Gierliński, M., Nikołajuk, M. & Czerny, B., 11 Jan 2008, In : Monthly Notices of the Royal Astronomical Society. 383, 2, p. 741-749 9 p.
X-ray irradiation in XTE J1817-330 and the inner radius of the truncated disc in the hard state
Gierliński, M., Done, C. & Page, K., 1 Aug 2008, In : Monthly Notices of the Royal Astronomical Society. 388, 2, p. 753-760 8 p.
An absorption origin for the soft excess in Seyfert 1 active galactic nuclei
Middleton, M., Done, C. & Gierliński, M., 17 Oct 2007, In : Monthly Notices of the Royal Astronomical Society. 381, 4, p. 1426-1436 11 p.
Analysing the atolls: X-ray spectral transitions of accreting neutron stars
Gladstone, J., Done, C. & Gierliński, M., 11 Jun 2007, In : Monthly Notices of the Royal Astronomical Society. 378, 1, p. 13-22 10 p.
neutron stars
Dependence of the orbital modulation of X-rays from 4U 1820-303 on the accretion rate
Zdziarski, A. A., Gierliński, M., Wen, L. & Kostrzewa, Z., 21 May 2007, In : Monthly Notices of the Royal Astronomical Society. 377, 3, p. 1017-1023 7 p.
X Ray Timing Explorer
Modelling the behaviour of accretion flows in X-ray binaries: Everything you always wanted to know about accretion but were afraid to ask
Done, C., Gierliński, M. & Kubota, A., 1 Dec 2007, In : Astronomy and Astrophysics Review. 15, 1, p. 1-66 66 p.
The superorbital variability and triple nature of the X-ray source 4U 1820-303
Zdziarski, A. A., Wen, L. & Gierliński, M., 21 May 2007, In : Monthly Notices of the Royal Astronomical Society. 377, 3, p. 1006-1016 11 p.
Black hole spin in GRS 1915+105
Middleton, M., Done, C., Gierliński, M. & Davis, S. W., 11 Dec 2006, In : Monthly Notices of the Royal Astronomical Society. 373, 3, p. 1004-1012 9 p.
radiative transfer
Consistency of the black hole mass determination in AGN from the reverberation and the X-ray excess variance method
Nikołajuk, M., Czerny, B., Ziółkowski, J. & Gierliński, M., 11 Aug 2006, In : Monthly Notices of the Royal Astronomical Society. 370, 3, p. 1534-1540 7 p.
Truncated disc versus extremely broad iron line in XTE J1650-500
Done, C. & Gierliński, M., 1 Apr 2006, In : Monthly Notices of the Royal Astronomical Society. 367, 2, p. 659-668 10 p.
K lines
relativistic effects
X-ray spectral transitions of black holes from RXTE all-sky monitor
Gierliński, M. & Newton, J., 1 Aug 2006, In : Monthly Notices of the Royal Astronomical Society. 370, 2, p. 837-844 8 p.
GRS 1915+105: The distance, radiative processes and energy-dependent variability
Zdziarski, A. A., Gierliński, M., Rao, A. R., Vadawale, S. V. & Mikolajewska, J., 1 Jul 2005, In : Monthly Notices of the Royal Astronomical Society. 360, 3, p. 825-838 14 p.
proportional counters
Gamma Ray Observatory
Patterns of energy-dependent variability from Comptonization
Gierliński, M. & Zdziarski, A. A., 11 Nov 2005, In : Monthly Notices of the Royal Astronomical Society. 363, 4, p. 1349-1360 12 p.
electron distribution
Physics of accretion in the millisecond pulsar XTE J1751 - 305
Gierliński, M. & Poutanen, J., 1 Jun 2005, In : Monthly Notices of the Royal Astronomical Society. 359, 4, p. 1261-1276 16 p.
pulsars
optical thickness
Scaling variability from stellar to supermassive black holes
Done, C. & Gierliński, M., 21 Nov 2005, In : Monthly Notices of the Royal Astronomical Society. 364, 1, p. 208-216 9 p.
radiant flux density
Black hole accretion discs: Reality confronts theory
Gierliński, M. & Done, C., 21 Jan 2004, In : Monthly Notices of the Royal Astronomical Society. 347, 3, p. 885-894 10 p.
GRS 1915+105: The brightest Galactic black hole
Done, C., Wardziński, G. & Gierliński, M., 1 Apr 2004, In : Monthly Notices of the Royal Astronomical Society. 349, 2, p. 393-403 11 p.
Contact Gierlinski, Marek


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Organization That Sued MLB Over All Star Game Brutally Weighs in on Stacey Abrams
By Chris Queen Dec 02, 2021 4:49 PM ET
AP Photo/Seth Wenig, File
On Wednesday, Georgia's governor failed gubernatorial candidate and professional grievance monger Stacey Abrams announced that she's going to run for reelection challenge Gov. Brian Kemp in 2022.
An organization that sued Major League Baseball over moving the All-Star Game from Atlanta earlier this year has weighed in on Abrams' candidacy.
The Job Creators Network sued MLB over their move, asserting that:
Moving the MLB All-Star game from Atlanta to Denver has done real harm to the communities of Atlanta, Cobb County and the state of Georgia:
More than 8000 hotel reservations were canceled.
Revenues from ticket sales, concessions and events at Truist Park – including the Futures Game and Home Run Derby Contest – by the more than 41,000 fans expected, were lost.
According to Cobb County Chief Financial Officer William Volckmann, the county would receive a "robust return" on its roughly $2 million investment to host the events. Previous MLB All-Star events have generated between $37 million and $190 million for their host communities.
Atlanta is 51% African-American, Denver is 9% African-American. U.S. Census data indicates there are roughly 7.5 times more African-American-owned businesses in Georgia than Colorado.
Job Creators Network wound up withdrawing the suit.
Related: Braves Fans Rejoice as MLB Backpedals
Their CEO, Alfredo Ortiz, made a brutal statement on Thursday regarding the Abrams campaign announcement:
"I'm appalled that someone who purposely harmed the small business community of Atlanta by encouraging Major League Baseball to move the All-Star Game to Colorado would have the nerve to run for Georgia Governor. If she has campaign ambitions, I suggest she run for Mayor of Denver. She's done much more to help the citizens there than anyone in Georgia."
Meanwhile, Kemp appeared on the Erick Erickson Show this afternoon to weigh in on Abrams, and he said he's ready for the fight.
"I've been a writer as long as I've known what writing is," says Chris Queen. Blessed with a wild imagination and a desire to create, Chris writes prose, fiction, songs, and reviews, and he shares whatever is on his mind on his website, chrisqueen.live.
Born in Marietta, Ga., Chris has called Covington his home since he was five years old. An alumnus of the University Of Georgia, Chris is an Editor and Columnist at PJ Media, where he has written for over 10 years. He has also written for The Resurgent, NewsReal Blog, and Celebrations Magazine.
Chris is a fan of anything involving his beloved Georgia Bulldogs and is a Disney aficionado, having visited Walt Disney World over 40 times, and he enjoys spending time with family and friends and especially spoiling his nieces Kenzie, Kayla, and Hadley. He is the author of the forthcoming book Neon Crosses: A Native Son's Guide to the South.
For media inquiries, please contact [email protected].
Read more by Chris Queen
Tags: WOKE


Bradley spends much of his time as an environmental field technician collecting soil, groundwater, and asbestos samples. He's 40-hour Hazardous Waste Operations and Emergency Response (HAZWOPER) certified and is licensed to perform asbestos work in Iowa, having received both Asbestos Abatement Contractor/Supervisor Training and Asbestos Inspector Training. Bradley is also certified to collect groundwater samples in Nebraska.
Like all of the Impact7G employees, Brad enjoys spending time in the Great Outdoors. He especially likes hiking because it's accessible to everyone from beginners to experts. One of the biggest bucket list items Brad hopes to cross off is to see the Northern Lights.


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Absolute and Relative Morbidity Burdens Attributable to Various Illnesses and Injuries, Non-service Member Beneficiaries of the Military Health System, 2020
5/1/2021 By: Armed Forces Health Surveillance Branch
Medical Surveillance Monthly Report
What Are the New Findings?
In 2020, mental health disorders accounted for the largest proportions of the morbidity and health care burdens that affected the pediatric and younger adult beneficiary age groups. Among adults aged 45–64 years, musculoskeletal diseases accounted for the most morbidity and health care burdens, and among adults aged 65 years or older, cardiovascular diseases accounted for the most. As in previous years, the results of this analysis demonstrate that most health care services in the Military Health System are delivered to non-service member beneficiaries rather than to service members.
What Is the Impact on Readiness and Force Health Protection?
Illness and injury among military family member dependents may negatively impact service members' readiness and their focus on the mission by contributing to stress or by affecting the mental health status of the service member. The provision of health care services to non-service member beneficiaries is an important benefit that can improve military family readiness and, in turn, improve the overall readiness of the force.
Individuals who are eligible for care through the Military Health System (MHS) ("beneficiaries") include active component service members and their eligible family members, activated National Guard and Reserve service members and their eligible family members, and retirees and their eligible family members. In fiscal year 2019, there were approximately 9.57 million beneficiaries eligible for health care in the MHS: 1.40 million active duty and activated reserve component service members, 1.66 million active duty family members, 190,000 Guard/Reserve members, 810,000 Guard/Reserve family members, and 5.51 million retirees and their family members.1 Some beneficiaries of MHS care do not enroll in the health care plans provided by the MHS (e.g., they use insurance through their own employment), and some of those who are enrolled do not seek care through the MHS.
MHS beneficiaries may receive care from resources provided directly by the Uniformed Services (i.e., military medical treatment facilities [MTFs]) or from civilian health care resources (i.e., outsourced [purchased] care) that supplement direct military medical care.1 In 2020, approximately 6.28 million non-service member beneficiaries utilized inpatient or outpatient services provided by the MHS (data source: the Defense Medical Surveillance System [DMSS]).
Since 1998, the MSMR has published annual summaries of the numbers and rates of hospitalizations and outpatient medical encounters to assess the health care burdens of 16 categories of illnesses and injuries among active component military members. Beginning in 2001, the MSMR complemented those summaries with annual reports on the combined health care burden of both inpatient and outpatient care for 25 categories of health care. Since then, the MSMR s annual burden issue has contained a report on hospital care, ambulatory care, and the overall burden of care each for active component service members. In 2014, for the first time and using similar methodology, the MSMR published a report that quantified the health care burden for illnesses and injuries among non-service members in calendar year 2013.2 The current report represents an update and provides a summary of care provided to non-service members in the MHS during calendar year 2020. Health care burden estimates are stratified by direct versus outsourced care and across 4 age groups of health care recipients.
The surveillance period was 1 Jan. through 31 Dec. 2020. The surveillance population included all non-service member beneficiaries of the MHS who had at least 1 hospitalization or outpatient medical encounter during 2020 either through a military medical facility/ provider or a civilian facility/provider (if paid for by the MHS). For this analysis, all inpatient and outpatient medical encounters were summarized according to the primary (first-listed) diagnoses documented on administrative records of the encounters if the diagnoses were reported with International Classification of Diseases, 10th Revision (ICD-10) codes that indicate the natures of illnesses or injuries (i.e., ICD10 codes A00–T88). Nearly all records of encounters with first-listed diagnoses that were Z-codes (care other than for a current illness or injury—e.g., general medical examinations, after care, vaccinations) or V/W/X/Y-codes (indicators of the external causes but not the natures of injuries) were excluded from the analysis; however, encounters with primary diagnoses of Z37 ("outcome of delivery, single liveborn") were retained.
For summary purposes, all illness- and injury-specific diagnoses (as defined by the ICD-10) were grouped into 153 burden of disease-related conditions and 25 major categories based on a modified version of the classification system developed for the Global Burden of Disease Study.3 The methodology for summarizing absolute and relative morbidity burdens vs described on page 2 of this issue of the MSMR. Results were stratified by source of health care (direct [military treatment facilities] vs outsourced [non-military medical facilities]) and by age group (0–17 years, 18–44 years, 45–64 years, and 65 years or older). For the purposes of the analysis of morbidity burdens within the youngest age group, developmental disorders were classified as mental health disorders.
In the population of non-service member MHS care recipients in 2020, there were more females (56.9%) than males (43.1%); more infants, children, and adolescents (those younger than 20 years old: n=1.49 million; 23.8%) and more seniors (those aged 65 years or older: n=2.07 million; 33.0%) than younger (aged 20–44 years: n=1.27 million; 20.3%) or older (aged 45–64 years: n=1.45 million; 23.0%) adults (data not shown)
In 2020, a total of 6,283,982 non-service member beneficiaries of the MHS had 82,165,960 medical encounters (Table). Thus, on average, each individual who accessed care from the MHS had 13.1 medical encounters over the course of the year. The top 3 morbidity-related categories, which accounted for more than one-third (35.5%) of all medical encounters, were signs/symptoms and ill-defined conditions (12.0%), mental health disorders (11.9%), and musculoskeletal diseases (11.5%) (Figures 1a, 1b). The illness/injury categories that affected the most beneficiaries who received any care were signs/symptoms and ill-defined conditions (45.9%), injury/poisoning (31.3%), and musculoskeletal diseases (28.2%).
Injury/poisoning accounted for more hospital bed days (n=974,618) than any other illness/injury category and 16.1% of all hospital bed days overall (Figures 1a, 1b). An additional 43.2% of all bed days were attributable to cardiovascular diseases (15.7%), infectious/parasitic diseases (12.6%), mental health disorders (9.3%), and digestive diseases (5.6%).
Of note, among all non-service member beneficiaries in 2020, maternal conditions (including pregnancy complications and delivery) accounted for relatively more hospital bed days (n=312,268; 5.2%) than individuals affected (n=158,558; 2.5%) (Figure 1a).
Direct CareDirect care refers to military hospitals and clinics, also known as "military treatment facilities" and "MTFs."Direct care vs. outsourced care
In 2020, among non-service member beneficiaries, most medical encounters (90.2%) were in non-military medical facilities (outsourced care) (Table). Of all beneficiaries with any illness- or injury-related encounters during the year, many more received exclusively outsourced care (n=4,654,433; 74.1%) than either military medical (direct) care only (n=659,160; 10.5%) or both outsourced and direct care (n=970,389; 15.4%). By far, most inpatient care (93.3% of all bed days) was received in non-military facilities.
The proportions of medical encounters by morbidity-related categories were broadly similar for direct and outsourced care (Figures 2a, 2b, 3a, 3b). However, encounters for musculoskeletal diseases, cardiovascular diseases, and neurological conditions were relatively more common in outsourced (11.9%, 9.3%, and 5.2%, respectively) compared to direct (8.2%, 5,7%, and 2.7%, respectively) care.
Maternal conditions accounted for 22.1% of all direct care bed days but only 3.9% of all outsourced care bed days (Figures 2a, 2b, 3a, 3b). However, mental health disorders, infectious/parasitic diseases, cardiovascular diseases, injury/poisoning, and neurologic conditions accounted for relatively more of all outsourced than direct care bed days (% of outsourced vs. % of direct care bed days: mental health disorders, 9.7% vs. 3.7%; infectious/parasitic diseases, 13.0%, 7.6%; cardiovascular, 16.1% vs. 10.8%; injury/poisoning, 16.4%, 12.2%; neurologic conditions, 5.3% vs. 1.4%).
Pediatric beneficiaries (aged 0–17 years)
In 2020, pediatric beneficiaries accounted for 13.7% of all medical encounters, 21.5% of all individuals affected, and 7.4% of all hospital bed days (Table). On average, each affected individual had 8.3 medical encounters during the year.
Mental health disorders accounted for slightly more than two-fifths (40.5%; n=4,546,586) of all medical encounters and 59.9% of all hospital bed days (n=268,522) among pediatric beneficiaries (Figures 4a, 4b). On average, each pediatric beneficiary who was affected by a mental health disorder had 15.8 mental health disorder-related encounters during the year. More than two-thirds (67.1%) of all medical encounters for mental health disorders among pediatric beneficiaries were for autistic disorder (33.6%), followed by developmental disorders of speech and language (23.3%), and attention deficit disorders (10.1%) (Figures 4c, 4d). On average, there were 47.9 autism-related encounters per individual affected with autistic disorder and 16.9 encounters for developmental disorders of speech and language per individual affected with those specific disorders (data not shown). Despite the high numbers of encounters associated with these 3 categories of mental health disorders, slightly more than three-quarters (75.8%) of mental health disorder-related hospital bed days were attributable to mood disorders, and 28.2% of mood disorder-related bed days were attributable to "disruptive mood dysregulation disorder" (data not shown).
Among pediatric beneficiaries overall, "conditions arising during the perinatal period" (i.e., perinatal conditions) accounted for the second most hospital bed days (n=43,821; 9.8%) (Figures 4a, 4b). Of note, among pediatric beneficiaries with at least 1 illness- or injury-related diagnosis, those with malignant neoplasms had the second highest number of related encounters per affected individual (14.0). The highest numbers of malignant neoplasm-related encounters were attributable to leukemias, "all other malignant neoplasms," and brain neoplasms, while the highest numbers of bed days were attributable to leukemias, brain neoplasms, and "all other malignant neoplasms" (data not shown).
Finally, respiratory infections (including upper and lower respiratory infections and otitis media) accounted for relatively more medical encounters among pediatric beneficiaries (7.2% and 2.2%, respectively) when compared to any older age group of beneficiaries (Figures 4b, 5b, 6b, and 7b).
Beneficiaries aged 18–44 years
In 2020, non-service member beneficiaries aged 18–44 years accounted for 15.1% of all medical encounters, 22.5% of all individuals affected, and 11.3% of hospital bed days (Table). On average, each individual affected with an illness or injury (any cause) had 8.7 medical encounters during the year.
Among beneficiaries aged 18–44 years, the morbidity-related category that accounted for the most medical encounters was mental health disorders (n=2,774,051; 22.4% of all encounters) (Figures 5a, 5b). Among these adult beneficiaries, mental health disorders accounted for slightly more than a quarter (25.5%) of all bed days, and, on average, each adult affected by a mental health disorder had 7.7 mental health disorder-related encounters during the year. Mood disorders (30.9%), anxiety disorders (31.5%), and adjustment disorders (17.7%) accounted for approximately four-fifths (80.1%) of all mental health disorder-related medical encounters among beneficiaries aged 18–44 years (data not shown).
Among adults aged 18–44 years, maternal conditions accounted for more than two-fifths (45.6%) of all bed days and, on average, 6.3 medical encounters per affected individual (Figures 5a, 5b). Normal deliveries accounted for 10.4% of maternal condition-related medical encounters (data not shown). Adults aged 18–44 years accounted for nearly all (99.4%) maternal condition-related bed days among beneficiaries not in military service. Although adults aged 18–44 years had the second lowest percentage of total medical encounters (15.1%), if morbidity burdens associated with maternal conditions were excluded from the overall analysis, this age group would account for even lower percentages of total medical encounters (13.9%) and the lowest percentage of total hospital bed days (6.1%) when compared to any other age group (data not shown).
Among beneficiaries aged 18–44 years with at least 1 illness or injury-related diagnosis, those with malignant neoplasms had the second most (along with maternal conditions) category-specific encounters per affected individual (6.5). Of all malignant neoplasms, breast cancer accounted for the most malignant neoplasm-related encounters (28.9% of the total) (data not shown).
In 2020, non-service member beneficiaries aged 45–64 years accounted for 20.9% of all medical encounters, 23.0% of all individuals affected, and 15.2% of hospital bed days (Table). On average, each affected individual had 11.9 medical encounters during the year.
Of all morbidity-related categories, musculoskeletal diseases accounted for the most medical encounters (n=2,476,302; 14.4%) among older adult beneficiaries (Figures 6a, 6b). In addition, in this age group, back problems accounted for 43.9% of all musculoskeletal disease-related encounters (data not shown). Injury/poisoning accounted for more hospital bed days (16.5% of the total) than any other category of illnesses or injuries, and other complications not otherwise specified (NOS) and leg injuries accounted for 44.5% and 18.9%, respectively, of all injury/poisoning-related bed days (data not shown). Digestive diseases accounted for a larger percentage (8.5%) of total hospital bed days among beneficiaries in this age group compared to those in the other age groups.
The most medical encounters per affected individual were associated with malignant neoplasms (6.5), mental health disorders (6.2), musculoskeletal diseases (4.9), neurologic conditions (4.6), injury/ poisoning (4.3), respiratory diseases (4.3), and maternal conditions (4.2) (Figures 6a, 6b). Malignant neoplasms (8.1%) accounted for a larger proportion of total bed days among beneficiaries aged 45–64 years than among the other age groups of beneficiaries. Breast cancer accounted for nearly one quarter (24.1 %) of all malignant neoplasm-related encounters among older adult beneficiaries (data not shown).
Beneficiaries aged 65 years or older
In 2020, non-service member beneficiaries aged 65 years or older accounted for approximately half (50.3%) of all medical encounters, nearly one-third (33.0%) of all individuals affected, and approximately two-thirds (66.2%) of hospital bed days (Table 1). On average, each affected individual had 20.0 medical encounters during the year.
Of all morbidity-related categories, musculoskeletal diseases (n=5,832,066; 14.1%) and cardiovascular diseases (n=5,579,928; 13.5%) accounted for the most medical encounters, but cardiovascular diseases accounted for the most bed days (788,950 days; 19.7%) Figures 7a, 7b). Back problems accounted for a little more than one-third (35.8%) of all musculoskeletal disease-related medical encounters and 37.0% of hospital bed days (data not shown). Taken together, essential hypertension (26.8%), ischemic heart disease (13.7%), and cerebrovascular disease (10.0%) accounted for slightly more than half (50.5%) of all cardiovascular disease-related medical encounters, and cerebrovascular disease accounted for over one-third (33.7%) of all cardiovascular disease-related bed days (data not shown).
Among the oldest age group of beneficiaries, the most medical encounters per affected individual were associated with musculoskeletal diseases (6.3), malignant neoplasms (5.8), respiratory diseases (5.8), respiratory diseases (5.6), diseases of the genitourinary system (5.4), mental health disorders (5.1), and cardiovascular diseases (4.9) (Figure 7a). In this age group, melanomas and other skin cancers (19.6%); prostate cancer (14.5%); breast cancer (12.3%); and trachea, bronchus, and lung cancers (10.1%) accounted for more than half (56.5%) of all malignant neoplasm-related encounters (data not shown). Chronic obstructive pulmonary disease accounted for nearly one-third of all medical encounters (32.4%) and 21.4% of all bed days attributable to respiratory diseases (data not shown).
Infectious and parasitic diseases (15.6%) accounted for a larger proportion of total bed days among the oldest age group compared to the other age groups of beneficiaries (Figures 7a, 7b). Coronavirus disease 2019 (COVID-19) accounted for more than one-quarter (27.4%) of infectious/parasitic-related medical encounters and 44.9% of hospital bed days (data not shown). In contrast to infectious/parasitic diseases, mental health disorders accounted for smaller percentages of medical encounters (2.8%) and bed days (2.2%) among the oldest age group compared to the younger age groups.
This report documents that a large majority of the health care services for current illness and injury (excluding encounters with diagnoses identified by Z-codes) that are provided through the MHS to non-service member beneficiaries are delivered in non-military medical facilities (i.e., outsourced [purchased] care). The report also documents that there are pronounced differences in the types of morbidity and the natures of the care provided for evaluation and treatment across age groups of beneficiaries. Of particular note, individuals aged 65 years or older—33.0% of all non-service member beneficiaries—accounted for approximately half (50.3%) of all medical encounters and two-thirds (66.2%) of all hospital bed days delivered to all such beneficiaries.
In 2020, as in previous years, mental health disorders accounted for the largest proportions of the morbidity and health care burdens that affected the pediatric (aged 0–17 years) and younger adult (aged 18–44 years) beneficiary age groups. Developmental disorders were a significant driver of health care utilization among pediatric beneficiaries with 67.1% of medical encounters for mental health disorders attributable to autistic disorder, developmental speech/language disorders, or attention-deficit hyperactivity disorders. Of particular note, children affected by autistic disorder had, on average, 47.9 autism-related encounters each during the 1-year surveillance period.
Although mental health disorders also accounted for more medical encounters among young adult (18–44 years) beneficiaries than any other major category of illnesses or injuries, the proportion of all encounters attributable to mental health disorders was markedly lower among young adult (22.4%) than pediatric (40.5%) beneficiaries. Also, as expected, the mental health disorders that accounted for the largest health care burdens among younger adults (18–44 years)—mood, anxiety, and adjustment disorders—differed from those that most affected the pediatric age group.
It is not surprising that the highest numbers and proportions of hospital bed days among adults aged 18–44 years were for maternal conditions because this age group encompasses nearly all women of childbearing age. Among older adults (aged 45–64 years), musculoskeletal diseases were the greatest contributors to morbidity and health care burdens, and among adults aged 65 years or older, cardiovascular diseases accounted for the most morbidity and health care burdens.
Of musculoskeletal diseases, back problems were a major source of health care burden; of cardiovascular diseases, essential hypertension, ischemic heart disease, and cerebrovascular disease accounted for the largest health care burdens. These findings are not unexpected and reflect the inevitable effects of aging on the health and health care needs of the older segment of the MHS beneficiary population. However, many of the health conditions associated with the largest morbidity and health care burdens among beneficiaries in older age groups are also associated with unhealthy lifestyles (e.g., unhealthy diet, inadequate exercise, or tobacco use). As such, to varying extents, the most costly health conditions may be preventable and their disabling or life-threatening long-term consequences may be avoidable. It is important to note, however, that among the oldest group of beneficiaries, COVID-19 accounted for more than two-fifths (44.9%) of hospital bed days attributed to infectious/parasitic diseases. Illnesses and injuries that disproportionately contribute to morbidity and health care burdens in various age groups of MHS beneficiaries should be targeted for early detection and treatment by comprehensive prevention and research programs.
Department of Defense. Evaluation of the TRICARE Program: Fiscal Year 2020 Report to Congress: Access, Cost, and Quality Data Through Fiscal Year 2019. Accessed 6 May 2021. https://www. health.mil/Reference-Center/Reports/2020/06/29/ Evaluation-of-the-TRICARE-Program-Fiscal-Year2020-Report-to-Congress
Armed Forces Health Surveillance Center. Absolute and relative morbidity burdens attributable to various illnesses and injuries, non-service member beneficiaries of the Military Health System, 2013. MSMR. 2014;21(4):23–30.
Murray CJ and Lopez AD, eds. In: Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990 and Projected to 2020. Cambridge, MA: Harvard University Press; 1996:120–122.
MSMR Vol. 29 No. 10 - October 2022
A monthly publication of the Armed Forces Health Surveillance Division. This issue of the peer-reviewed journal contains the following articles: Surveillance trends for SARS-CoV-2 and other respiratory pathogens among U.S. Military Health System Beneficiaries, Sept. 27, 2020 – Oct. 2,2021; Establishment of SARS-CoV-2 genomic surveillance within the MHS during March 1 – Dec. 31 2020; Suicide behavior among heterosexual, lesbian/gay, and bisexual active component service members in the U.S. Armed Forces; Brief report: Phase I results using the Virtual Pooled Registry Cancer Linkage system (VPR-CLS) for military cancer surveillance.
Health Readiness & Combat Support | Public Health | Medical Surveillance Monthly Report
Viral hepatitis C, active component, U.S. Armed Forces, 2011–2020
This study reports updated numbers and incidence rates of hepatitis C virus (HCV) infection among active component members of the U.S. military using a revised case definition during a 10-year surveillance period between 2011 and 2020.
Update: Contraception Among Active Component Service Women, U.S. Armed Forces, 2017–2021
This report summarizes the annual prevalence of permanent sterilization, as well as use of long- and short-acting reversible contraceptives (LARCs and SARCs, respectively), contraceptive counseling services, and use of emergency contraceptives from 2017 through 2021 among active component U.S. service women.
Surveillance Snapshot: Influenza Immunization Among U.S. Armed Forces Healthcare Workers, August 2017–April 2022
Immunization Among U.S. Armed Forces Healthcare Workers
MSMR Vol. 29 No. 09 - September 2022
Update: Routine Screening for Antibodies to Human Immunodeficiency Virus, U.S. Armed Forces, Active and Reserve Components, January 2017–June 2022
This report provides an update through June 2022 of routine screening results for antibodies to the human immunodeficiency virus (HIV) among members of the active and reserve components of the U.S. Armed Forces. During the full 5 and 1/2-year surveillance period, the HIV seropositivity rates for active component service members were 0.21 positives per 1,000 members of the Army, 0.24 for the Navy, 0.16 for the Marine Corps, and 0.14 for the Air Force.
Evaluation of the MSMR Surveillance Case Definition for Incident Cases of Hepatitis C
The validity of military hepatitis C virus (HCV) surveillance data is uncertain due to the potential for misclassification introduced when using administrative databases for surveillance purposes. The objectives of this study were to assess the validity of the surveillance case definition used by the Medical Surveillance Monthly Report (MSMR) for HCV, the over and underestimation of cases from surveillance data, and the true burden of HCV disease in the U.S. military.
Letter to the Editor: Clarification of Hepatitis C Virus Screening with Case Definitions and Prevalence Among Trainees
We read with interest the brief report regarding the prevalence of Hepatitis C Virus (HCV) infection in basic military trainee blood donors by Kasper and colleagues in the November 2021 issue of the Medical Surveillance Monthly Report (MSMR),1 an update of a previous similar report
Brief Report: Menstrual Suppression Among U.S. Female Service Members in the Millennium Cohort Study
Menstrual suppression allows for the control or complete suppression of menstrual periods through hormonal contraceptive methods. In addition to preventing pregnancy, suppression can alleviate medical conditions and symptoms associated with menstruation such as iron deficiency anemia,1 eliminate logistical hygiene-related challenges, and improve quality of life.
MSMR Vol. 29 No. 08 - August 2022
Musculoskeletal Injuries During U.S. Air Force Special Warfare Training Assessment and Selection, Fiscal Years 2019–2021.
Musculoskeletal (MSK) injuries are costly and the leading cause of medical visits and disability in the U.S. military.1,2 Within training environments, MSK injuries may lead to a loss of training, deferment to a future class, or voluntary disenrollment from a training pipeline, all of which are impediments to maintaining full levels of manpower and resources for the Department of Defense.
Brief Report: Pain and Post-Traumatic Stress Disorder Screening Outcomes Among Military Personnel Injured During Combat Deployment.
The post-9/11 U.S. military conflicts in Iraq and Afghanistan lasted over a decade and yielded the most combat casualties since the Vietnam War. While patient survivability increased to the highest level in history, a changing epidemiology of combat injuries emerged whereby focus shifted to addressing an array of long-term sequelae, including physical, psychological, and neurological issues.
Prevalence and Distribution of Refractive Errors Among Members of the U.S. Armed Forces and the U.S. Coast Guard, 2019.
During calendar year 2019, the estimated prevalence of myopia, hyperopia, and astigmatism were 17.5%, 2.1%, and 11.2% in the active component of the U.S. Armed Forces and 10.1%, 1.2%, and 6.1% of the U.S. Coast Guard, respectively.
MSMR Vol. 29 No. 07 - July 2022
Establishment of SARS-CoV-2 Genomic Surveillance Within the Military Health System During 1 March–31 December 2020.
This report describes SARS-CoV-2 genomic surveillance conducted by the Department of Defense (DOD) Global Emerging Infections Surveillance Branch and the Next-Generation Sequencing and Bioinformatics Consortium (NGSBC) in response to the COVID-19 pandemic. Samples and sequence data were from SARS-CoV-2 infections occurring among Military Health System (MHS) beneficiaries from 1 March to 31 December 2020.


text:
100,000 Genomes Project
Asthma is a complex, long-term condition and we urgently need new scientific breakthroughs to find new treatments to reduce asthma attacks and ultimately to find a cure.
The 100,000 Genomes Project is a flagship project of the Department of Health that is working with universities and hospitals across the UK to understand the genetics of people with rare conditions. It aims to create a health service that uses knowledge about people's genes to more accurately understand, diagnose and develop treatments for conditions where that is currently not possible. Being part of the 100,000 Genomes Project could help spur the next wave of research to tackle severe asthma.
Why is Asthma UK fighting to include severe asthma in the 100,000 Genomes project?
We know that there are several different types of asthma but we are a long way from understanding the causes of these different types let alone having the tools for a GP to quickly spot these differences during diagnosis and then prescribe treatments tailored for that type.
The 100,000 Genomes Project focuses on rare conditions where we do not know enough about the underlying genetic cause. The current lack of scientific understanding means that many people may respond poorly to conventional treatments, and for people with some kinds of severe asthma there may be no effective treatments available. Working to include a specific type of severe asthma in this project could open the door to understanding the differences between people's asthmas at a genetic level. This could transform how we diagnose different forms of asthma, develop treatments and ensure that people receive the right treatments for their type of asthma.
The project has been backed with over £200 million to buy state-of-the-art genome sequencing equipment and to analyse the vast amounts of data produced. And the project is already having results, pinpointing the underlying genetic changes that cause debilitating conditions.
Watch this video to find out more about how the 100,000 Genomes Project works. Its aim is to sequence 100,000 genomes from 70,000 people making it the largest study of genomes in the world. This is a massive undertaking and will provide masses of data to drive medical research - the raw data from one genome alone is about 200Gb – equivalent to 4000 professional-grade photos!
What is Asthma UK working to achieve?
Understanding a key form of severe asthma
There is a strong case to investigate the link between severe eczema and severe asthma, with the genetic correlation between these conditions indicating shared causes. We want to include this form of asthma in the 100,000 Genomes Project to better understand its causes and potentially unlock better diagnosis and research into new treatments for it as a result.
Kick-starting further research into other forms of asthma
If understanding the different types of asthmas at a genetic level proves to be a fruitful way to increase the accuracy of diagnosis, and opens up new ways of thinking about how to develop effective treatments, it could start a whole new wave of asthma research.
What is Asthma UK doing to make this happen?
We are currently working with leading respiratory scientists and clinicians to apply for the inclusion of this specific type of asthma in the 100,000 Genomes Project.
If we are successful, this could be the beginning of a new level of understanding asthma, leading to better diagnostic tools and new treatments.
Thanks for your interest in receiving updates from Asthma UK via email. We will keep you informed about the work that we do and about asthma-related news, health advice, appeals, events, campaigns and research.
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Asthma needs research Increasing investment in asthma research


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If you have less than 25 full-time employees making an average of about $50,000 a year or less, you may qualify for a small business health care tax credit. Beginning in 2014, the tax credit is worth up to 50% of your contribution toward employee premium costs (up to 35% for tax-exempt employers), making the cost of providing health coverage lower. Also starting in 2014, the small business health care tax credit will only be available through SHOP coverage.
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New research out today reveals that people in Britain are losing touch with their home lives – missing their kids' birthdays and other important milestones like school plays, parents' evenings and award ceremonies – all because of work.
A survey of 2,000 working people in the UK, commissioned by on-demand staffing app Coople, has revealed that work is negatively impacting over half of Brits, with people admitting that their current workloads are drastically affecting their lives at home.
In fact, the research finds that poor work-life balance has been detrimental to parents' relationships with their children, with 11% saying working late and not 'switching off' has distanced them from their young ones.
The greatest discovery from the poll revealed that one in five (20%) parents say their work schedule has made them miss an important moment in their child's life, such as a birthday party (8%) or an important school event (12%).
Staggeringly, 28% of those that admitted to missing these important events have done so more than five times during their working life. 10% say they have missed their child's event once, 26% say they have done so twice, 29% three times, and 7% admit they've done so four times.
"This research has highlighted some concerning issues within the British working lifestyle, and it's sad to see that people are missing their kids' birthdays and important life events as a result of rigid work arrangements. These are once-in-a-lifetime occasions, so companies should be doing their best to make sure their staff are getting sufficient time off to spend with their family, friends and partners".
"It really highlights the detrimental effects of employment without flexibility. I believe there is a strong link between companies that emphasise an excellent work-life balance, and their staff's productivity, happiness and loyalty in the workplace.
Hopefully, this research will serve as a wake-up call to businesses across the UK to recognise and prioritise the importance of their staffs' personal well-being, and to put the right structures in place to create a better work-life balance".


A Prospect exclusive: A new analysis of Abramoff tribal money by a nonpartisan firm shows it's a Republican scandal.
(American Prospect) A new and extensive analysis of campaign donations from all of Jack Abramoff's tribal clients, done by a nonpartisan research firm, shows that a great majority of contributions made by those clients went to Republicans. The analysis undercuts the claim that Abramoff directed sums to Democrats at anywhere near the same rate.
# Abramoff's clients gave well over twice as much to Republicans than Democrats, while tribes not affiliated with Abramoff gave well over twice as much to Democrats than the GOP -- exactly the reverse pattern.
"It's very hard to see the donations of Abramoff's clients as a bipartisan greasing of the wheels," Morris, the firm's founder and a former investigations editor at the Los Angeles Times, told The Prospect (read the rest here).


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text:
Philip IV of France
by PHGCOM
published on 28 June 2019
Philip the Fair (r. 1285-1314 CE), Saint-Denis Basilica.
Based on Wikipedia content that has been reviewed, edited, and republished. Original image by PHGCOM. Uploaded by Ibolya Horvath, published on 28 June 2019 under the following license: Creative Commons Attribution-ShareAlike. This license lets others remix, tweak, and build upon a work even for commercial reasons, as long as they credit the author and license their new creations under the identical terms. When republishing on the web a hyperlink back to the original content source URL must be included. Please note that content linked from this page may have different licensing terms.
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PHGCOM, . (2019, June 28). Philip IV of France. World History Encyclopedia. Retrieved from https://www.worldhistory.org/image/10973/philip-iv-of-france/
PHGCOM, . "Philip IV of France." World History Encyclopedia. Last modified June 28, 2019. https://www.worldhistory.org/image/10973/philip-iv-of-france/.
PHGCOM, . "Philip IV of France." World History Encyclopedia. World History Encyclopedia, 28 Jun 2019. Web. 22 Jan 2022.