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I Mostly Read Think Again
Jennifer Murphy August 23, 2021
We record each session of The "I mostly Read It" Book Club and use transcription software to best collect the ideas shared and discussed each week. It's powerfully telling that, among the keywords the software identified in Think Again by Adam Grant, were humility, engaging, identity, agreements, questions, and conversation. These are rich and engaging themes in the book. What's
Ruthless Consistency: More than a Habit
On the third Wednesday of every month, the I Mostly Read It Book Club convenes to talk about a book that there is a decent chance not all of us read. But we are still ready to offer opinions on the topic! We designate a discussion leader to pick a book and help guide the rest of us as the
How Deep Is Your Focus?
In June, the I Mostly Read it Book Club examined Deep Work: Rules for Focused Success in a Distracted World by Cal Newport. So, in 2021, on the heels of a year-long pandemic, exploding social justice movements, and a tumultuous political landscape, she was again drawn to the book's relevance. "I was reminded when I reread it about the ability
Molly Monk and John Foster celebrate five years with NewBoCo
Rob Merritt July 16, 2021
NewBoCo welcomed two key team members five years ago this week. Today? Both John Foster and Molly Monk say they wouldn't want to be anywhere else. "The last five years have been a wild ride," says Molly, who currently serves as NewBoCo's Assistant Director of Development. "It was on my birthday five years ago that Eric Engelmann called me and
Lucky Number Seven for NewBoCo's David Tominsky
Rob Merritt May 20, 2021
Today we're saluting David "Old Man" Tominsky for a big anniversary. Of course, Old Man Tominsky isn't actually an old man. However, seven years ago today, he started as one of the first people — we think he says he was "Employee 1" — at NewBoCo. So he's definitely got an earned level of seniority on our team, and many
How Tiny Techies is preparing our youngest students for computer science
Since all schools will be offering some form of Computer Science soon, we need to prepare our students so that they're excited about learning this crucial subject. One way to do that is by introducing them to key Computer Science principles, such as creativity, looping, debugging, perseverance, and more, as early as possible. NewBoCo's Tiny Techies curriculum does just this without having to put
Our Events Coordinator celebrates a big event of her own!
Two years ago today, NewBoCo Events Coordinator Jourdan McChesney joined our team. She arrived just in time for EntreFEST 2019, and she's played a huge role in keeping our programming going throughout the "virtual events" era of the pandemic. Now, as we're gearing up for the return of in-person events with EntreFEST 2021, Jourdan is busier than ever. And if


Ranging from 614 to 1294 square feet, these dramatically spacious one- and two-bedroom residences center around a living-dining area that opens to the outdoors. Most units have large private balconies with glass railings. Heating and cooling is controlled by a zoned climate system. Wide-plank oak floors, polished quartz countertops, and up to 11-foot ceilings enhance the breezy feel. Kitchens are outfitted with Thermador kitchen appliances: 30" Professional five-burner gas ranges; stainless-steel refrigerator; microwave; Bosch dishwasher; Glacier White Quartz countertops and slab backsplash. Each unit has in-unit washer and dryer hookups and fresh air exhaust system. The bathrooms feature Rohl plumbing fixtures and accessories, American Standard Lyndon dual-flush toilet and a Kohler cast-iron tub.
This unit is a 704 sqft 1 bedroom, 1 bathroom with 84 sqft balcony.
147 Hope Williamsburg is surrounded by the best of Brooklyn, but when you're home, life centers around terrific common spaces that include the sky deck and multiple landscaped community gardens. The building features a light-filled lobby with virtual doorman and package room, resident's lounge, fitness center, baby stroller parking and private storage. Residents will feel free to confine the dirty work to the basement bike repair room and pet grooming station. On-site parking is available for purchase with electric car charging station available.


At Brighton Implant Clinic, Cosmetic Porcelain Veneers are offered to allow you to acquire a stunningly gorgeous beautiful smile. Do you happen to suffer from discolored, worn down, chipped or broken teeth? If so, you are not alone and it is very likely that your confidence and self-esteem has been severely dented. A beautiful, white smile is a highly coveted physical trait in the society we live in. Have you ever seen a gorgeous supermodel without those gorgeous, pearly whites? If you suffer from conditions that prevent you from having the same stunning smile as supermodels, you may want to consider Cosmetic Porcelain Veneers. Dental veneers are very thin shells made of porcelain and bonded to the front of teeth. This procedure of installing Cosmetic Porcelain Veneers requires little or no anesthesia and really is an amazing option to improve the appearance of your front teeth. Let's take a look at some of the primary benefits of having cosmetic porcelain veneers installed.
Porcelain Veneers are extremely natural looking since porcelain and tooth enamel are both white and translucent. This means that they react to light in similar ways. In fact, others will not even know that you had a procedure done to acquire that gorgeous new smile. However, they will be sure to notice that you have a beautiful smile. Another key advantage of having cosmetic porcelain veneers installed is that they are highly stain-resistant. Due to the fact that porcelain is a ceramic, stain-producing elements simply roll right off the surface. If you are a heavy coffee drinker or enjoy the occasional glass of red wine, you can be confident knowing that dental veneers will be exceptionally stain-resistant even for you. If you are self-conscious of yellow, permanently stained, crooked, chipped or mispositioned teeth, you can change your life for the better by having cosmetic porcelain veneers installed. Your physical appearance and consequently your self-esteem will be instantly boosted.
Brighton Implant Clinic will be your ideal choice for cosmetic porcelain veneers to be installed. At Brighton Implant Clinic, all laboratory work is produced in house, which means that you will be able to meet with the dental technician who will be designing your veneers. You can discuss the final appearance and specifications of your veneers directly with the technician, which means that you can be fully confident of the procedure well ahead of time. Additionally, you can be confident knowing that Brighton Implant Clinic is the most affordable advanced dentistry in the UK.
If you suffer from yellow, permanently stained, crooked, chipped or mispositioned teeth, do not despair. You can have the same stunningly gorgeous pearly whites that supermodels have. Brighton Implant Clinic offers cosmetic porcelain veneers that will help you boost your confidence and self-esteem to new highs. Cosmetic porcelain veneers are incredibly natural looking and highly stain-resistant even for the coffee and red wine drinkers. At Brighton Implant Clinic, you will have the unique opportunity to meet and interact directly with the dental technician who will be designing your own unique veneers. You can be confident knowing that you will receive Affordable Cosmetic Porcelain Veneers at Brighton Implant Clinic.
For more information about Cosmetic Porcelain Veneers please feel free to Contact Brighton Implant Clinic or Call us on 0800 111 6623.
A single dental implant and crown starts from £995 per tooth. If you need multiple teeth replaced the cost per tooth is much lower. We provide a free initial consultation which includes a report and treatment plan.


Central Standard is a craft distiller in Milwaukee. This particular product is a maceration of local coffee roaster Anodyne's beans with Central Standard's classic vodka. The vodka is distilled from Wisconsin rye in the model of Poland and Russia's vodkas. Their stills low-reflux design is meant to enhance the grain's natural flavors.
"There are certainly lots of unmistakable coffee aromas on this interesting vodka, but unfortunately many of the flavors skew toward over-roasted. The interplay of the rye spice with chocolatey coffee bean makes for a very intense palate that finishes spicy and a bit sharp. Perhaps the addition of dairy and/or Kahlua in a white or black Russian would bring everything together."


Everyone wants to get out of town during spring break. It's one of the longest breaks of the year that helps people disconnect from stressful daily routines. As a result, it's a popular time for people to travel since they have so much free time to devote to trips. While it's exciting to anticipate getting away, you have to first choose where you're going from a long list of popular spring break destinations for couples.
Vacation destinations will vary depending on the budget you're working with. You may be tempted to visit a place near your hometown, but when it's spring break, you should go big! If you're not sure where you'll go this year for spring break, read on for some travel inspiration. You may find a new place that will have you searching for the next flight out of town. Wherever you decide to go, use this year's spring break to make incredible memories and experience life in a whole new way.
Whether it's a short drive away or not, New Orleans is a great place to go when you're looking for a fun vacation. You'll arrive after the craziness of Mardi Gras season ends, so you won't get caught up in all the traffic and major crowds. Prices for hotels will also drop since their biggest tourist season of the year will be over.
Check around online to see if you can find great room rates. Look outside the famous French Quarter for the best prices. You'll still be able to find a nice place to stay within walking distance of everything if you spend a little time looking around at what's available. Afterward, you can check out fun attractions like Bourbon Street and Jackson Square to start planning what you'll do while you're there.
Spring is the best time for couples to visit Amsterdam. It's a time for festivals and parades, with the biggest attraction being All King's Day. Formerly All Queen's Day, this festival is celebrated with constant parties for people of all ages. Travel in a boat down the city's iconic canals to reach the fun, where you can spend every day trying new foods and celebrating with the locals.
Do you spend your days dreaming of a way you could experience an adventure in the most beautiful location? If so, Puerto Vallarta is calling your name. You can explore all day long, discovering places to hike, cave dive and zip line. A few minutes researching will help you plan a vacation to one of the best spring break destinations for couples.
This year, go to Svalbard, Norway to take advantage of all your free time with 24-hour daylight. There won't be any sunsets to end your days of fun. On the other hand, if you vacation toward the end of April, you'll get to see their northern lights whenever you want during their 24-hour nights. Decide what you'd both rather experience, then book the next flight out to Norway.
Key West is a classic spring break destination because it's a tropical getaway you can enjoy without ever leaving the United States. Fly into Miami and drive out to the Key West coast. It's a small town, so there will be budget-friendly hotels and entertainment to fill your days. Key West is the place to go if you want to disconnect from the stress of daily life and enjoy a quiet trip away with the person you love.
If Cabo San Lucas isn't on your bucket list, it's time to add it. It's known as a romantic place for couples to escape to, especially if either person cares to golf. There are multiple championship golf courses for you to try when you're not parasailing, snorkeling or horseback riding. There are so many things to do in Cabo San Lucas that it's made a name for itself as one of the best spring break destinations for couples from all over the world.
Myrtle Beach is one of the best-known beaches in the U.S. because it has something for everyone. Couples can enjoy the romantic beaches and dining in the area while families spend their time at amusement parks and family-friendly tourist spots. Walk the boardwalk to get a glimpse of the vintage side of Myrtle Beach, or hang out at their state park.
Every couple should get the chance to see Paris together when they have enough time to visit, like during spring break. Whether you want to go just to try their famous foods or you can't get enough of their art museums, you'll both have an incredible time in the city of lights. Spend some time looking at all the different places you could book a room with. It's a booming city, so there are endless hotel options, as well as rooms you can rent with locals.
Couples who prefer a getaway that's quieter but still romantic will love Savannah, Georgia. When you're not at the city market, you can cruise on a riverboat, walk through the state park or visit any of their historical sites that played key roles in United States history. Savannah has become one of the most loved spring break destinations for couples because it so perfectly combines its history with its bustling modern city life.
Spring break is the best time to visit St. Lucia because you'll experience their Jazz and Art Festival. For eight days, you can listen to many different kinds of live jazz music and peruse crafts from the best local jewelry makers, painters and wood carvers. You're bound to go home with unique treasures and memories of plenty of time spent on their white, sandy beaches.
No matter where you decide to go for your spring break, do plenty of research on every location you're considering. Certain events and festivals will be happening everywhere, and you may find that you prefer some over others. Talk with your partner to make the final decision, then enjoy your spring break in the most fun and romantic place you can get away to.


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NASA Tracks Big Dust Storm on Mars
Nov. 24, 2012, 2:47 PM UTC / Source: Space.com
By SPACE.com Staff
A NASA spacecraft is keeping tabs on a vast dust storm on Mars that has spawned changes in the Martian atmosphere felt by two rovers on the planet's surface.
The Martian dust storm was first spotted by NASA's Mars Reconnaissance Orbiter (MRO) on Nov. 10 and has been tracked ever since. The agency's Mars rover Opportunity has seen a slight drop in atmospheric clarity due to the storm. Meanwhile the newer Curiosity rover — which has a built-in weather station — has seen a drop in air pressure and slightly increased nighttime temperatures halfway around the planet from Opportunity, NASA officials said.
"This is now a regional dust storm," Rich Zurek, NASA's chief Mars scientist at the Jet Propulsion Laboratory in Pasadena, Calif., said in a statement Wednesday (Nov. 21). "It has covered a fairly extensive region with its dust haze and it is in a part of the planet were some regional storms have grown into global dust hazes."
NASA is combining observations by the Curiosity rover and MRO to create a complete picture of the Martian dust storm. The Spain-built Rover Environmental Monitoring Station on Curiosity gives scientists a real-time look at conditions over the rover's position inside Gale Crater.
The Mars Color Imager on MRO was built by Malin Space Science Systems in San Diego. It was Malin's Bruce Cantor who first spotted the storm in photos from the powerful Mars camera on Nov. 10. [ Amazing Mars Photos by MRO Spacecraft ]
"For the first time since the Viking missions of the 1970s, we are studying a regional dust storm both from orbit and with a weather station on the surface," Zurek said.
Because the dust from the current storm is absorbing sunlight instead of reflecting it, a warming effect 16 miles (25 kilometers) above the Martian tempest has been seen by MRO. The effect, first recorded by MRO's Mars Climate Sounder on Nov. 16, has led to a temperature increase of 45 degrees Fahrenheit (25 degrees Celsius) so far.
Warmer temperatures are not confined to the Martian south. The circulation of the Martian atmosphere has also led to a hot spot in the planet's northern polar regions. The temperature on Mars is typically about minus 80 degrees F (minus 60 degrees C), but can vary depending on location and the Martian season.
Regional dust storms on Mars were observed in 2001 and 2007, but not between those years or in the time since. The Martian year lasts two Earth years, with major dust storm events following a seasonal pattern. Dust storm season on Mars began a few weeks ago as the Martian spring began in the planet's southern hemisphere, NASA officials said.
"One thing we want to learn is why do some Martian dust storm get to this size and stop growing, while others this size keep growing and go global," Zurek said.
A global dust storm on Mars could have implications for the Opportunity and Curiosity rovers. If the current dust storm were to expand to cover the Red Planet, the dust settling on Opportunity's solar panels could reduce the rover's power supply. Opportunity has been exploring the plains of Meridiani Planum since its 2004 landing on Mars.
NASA's newer Mars rover Curiosity, meanwhile, would likely see increased haze in its photos of nearby terrain, as well as an above normal air temperature. The 1-ton Curiosity rover landed on Mars on Aug. 5 and is powered by a radioisotope thermoelectric generator that is unaffected by dust storms.
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What Did Curiosity Find On Mars? | Exclusive Video
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SPACE.com Staff

redpajama_set_name: RedPajamaCommonCrawl


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il Proconsul, genere di primati quadrupedi estinti
il Proconsole, dal latino Proconsul, magistrato romano

redpajama_set_name: RedPajamaWikipedia


As you know, the hobby of reptile keeping has never been more popular.
There are currently more reptiles being kept as pets within Europe and America than there are cats, or dogs! And the trend is set to continue rising for the foreseeable future, with record numbers of newbie hobbyists joining daily.
We always welcome new opportunities to work with great resellers, both in the UK and internationally. So, whether you are an independent pet store in the UK, or a major wholesaler overseas, please do get in touch with us, using the form below. We'd love to hear from you.
To qualify for a trade account you need to be a legitimate pet store retailer, online retailer or wholesaler. Regrettably we don't accept trade applications from persons wanting to trade on third party websites such as ebay or Amazon for example.
Vividarium do not permit any resellers to sell, display, or advertise on third party websites. If you apply to be a reseller of our products you are expected to accept these terms.
If you are a pet store chain; How many outlets do you have?
If you are a wholesaler; Approximately how many stores do you distribute to?
Approximately how many Vividarium products would you expect to purchase on an average monthly basis?


Industrial and commercial heating specialist Turnbull & Scott has officially merged with CEH ltd.
This acquisition has broadened the scope of the heating solutions that the company can provide as CEH specialises in electric space heating. CEH also specialises in producing 'high end' heating products for high street stores and restaurants, as well as sports venues and art galleries.


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for the Spain they believed to be better: Quatre camins memorial
The Terç de Requetès de la Mare de Déu de Montserrat was a battalion-type Carlist infantry unit, forming part of Nationalist troops during the Spanish Civil War. It is known as one of two Catalan units fighting against the Republican. It is also recognized as the unit which recorded extraordinarily high 20% killing in action ratio, with corresponding average Nationalist figure estimated at 6%.
According to Espais de Memoria / Memorial Democràtic and COMEBE "Quatre Camins (Four Paths) takes its name from the intersection of the four roads which lead to Vilalba dels Arcs, la Fatarella, Corbera d'Ebre and Gandesa.
Overlooking the roads are twin hills, one each side of the road, separated by 250 metres and rising of 481 metres above the sea level.The hill closer to Vilalba dels Arcs, known as Quatre Camins, was held by the troops of the Montserrat Carlist infantry regiment. The other hill, known as Punta Targa, had been in the hands of Republican troops since the 25 of July, the day the Battle of the Ebro began.
Due to the strategic importance of the crowsroad, the Republicans fortified Punta Targa with four machine gun nests connected by trenches covered with a double layer of logs and dirt. In front of these positions they dug out foxholes for sharpshooters, and between them they ran a double line of triple barbed wire.
In addition to these defences, the Republican had two machine gun platoons and one 50 mm mortar platoon at their disposal, as well as anti-tank guns, heavy mortars and armoured vehicles nearby.
The Nationalist army's third offensive on the Ebro front was intended to dislodge the Republican forces from Vilalba dels Arcs to protect Gandesa's left flank and prevent it from being surrounded.
On the 19th of August they launched their offensive with four divisions and more than 170 artillery pieces and air support. The Republican line had to be broken in three places. One of these places was Quatre Camins, where three battalions of the 74th division attacked: battalion B from Ceuta, the 131st from Bailen and the Nostra Señora de Monserrat Carlist Infantry Regiment. After three hours of preparation, at exactly noon, the Nationalist army units were to attack Punta Targa, which was defended by the 121st battalion if the 31st Republican Mixed Brigade. However, at the designated moment of attack, only the Montserrat Infantry Regiment emerged from the trenches. It was all over in just a few minutes, and the Nationalists did not achieve their objective. The men of the Regiment left 50 dead and 173 injured under the grapevines and returned to carry them away the night after Republicans has autorised a cease-fire. The following day, under heavy enemy fire, Republican troops fell back from their positions on Punta Targa, which were then occupied by the survivors of the Montserrat Infrantry Regiment."
In 1968 the brotherhood Germandat d' excombatents Terç de Requetès de la Mare de Déu de Montserrat, an organisation founded in the late 1950, decided to built a memorial to those who died in Quatre Camins (Vilalba dels Arcs). The memorial consists of two monuments, one in Quatre Camins and the other in Punta Targa. These monuments are linked by a 100 metres path, a Via Crucis which is flanked by monoliths with the carved names of the requetés killed in this war front. For the brotherhood this Via Crucis was a sign ot the reconciliation between the combatants of the two armies.
This memorial, however, is periodically vandalised. In this way in December 2018 part of the memorial was partially destroyed.
These photos were taken in August 2019.


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Sussanne Khan Finally Reveals The 'Real Reason' Behind Her Divorce With Hrithik Roshan!
AllBollywoodCelebscoopHollywoodOriginals
Isha SharmaUpdated on Jun 12, 2016, 11:09 IST
In 2014, when Hrithik Roshan announced his split with wife Sussanne Khan, the world took time to believe this sad news. After being the 'perfect' real life couple of B-town, this news also sparked off several rumors of a 'third' person being involved in the split.
While Sussanne's proximity and public appearances with Arjun Rampal led to several rumors, she chose to maintain a graceful silence on the same. During the whole Kangana and Hrithik fiasco, the way Sussanne showed support to Hrithik was commendable too.
In an interview with a magazine, Sussanne Khan for the first time ever spoke about her divorce with Hrithik. In a very honest confession, she said:
"We had reached a stage in our lives where I decided that it's better we weren't together. It was important to be aware and not be in a false relationship."
And if you think that exes can't be friends or be in a cordial relationship, wait till you read Sussanne's mature take on it. She added:
"We are close (friends). We do chat a lot even though we don't hangout together anymore. But above all, we are very committed to our children. We are respectful towards each other. When children are involved, it's important to put our differences aside and protect them."
What a brilliant example they have set, right? Thanks for setting such a nice example for the world that even if a marriage falls apart, two individuals can still give their best to raise the children.


I absolutely love this colour. The amplified formula definately keeps it's freshly dyed brightness for longer than the normal one. I've never used any other brand so I don't have anything to compare it against but I still think it's pretty damn good! The whiter your hair is the brighter it'll be. Covering the dye (with cling film or shower cap etc) and heating with a hairdryer worked wonders for me too.


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University of Iowa engaged in "viewpoint discrimination" when de-registering Christian union
A federal appeals court has ruled that the University of Iowa violated the free-speech rights of InterVarsity Christian Fellowship (IVCF) by de-registering the Christian organisation.
While all students are welcome to attend IVCF events, leadership positions are restricted to those who subscribe to the organisation's statement of faith.
This restriction of leadership positions to professing Christians was in the view of the University of Iowa, which de-registered IVCF in 2018, a form of discrimination.
The appeal court upheld the right of InterVarsity Christian Fellowship to require leaders to subscribe to a Christian statement of faith
However, in a decision issued on 16 July 2021 the US Eighth Circuit Court of Appeal ruled that the university had acted unconstitutionally in violating IVCF's First Amendment right to freedom of speech.
Circuit Judge Jonathan Kobes also stated that the university had itself engaged in "viewpoint discrimination" by not applying the same standard to other student societies. Several organisations were allowed to require that their members hold particular views and opinions.
The court was told that university administrators overseeing student societies were instructed to "look at religious student groups first" and did not apply the same criteria to other groups.
"What the university did here was clearly unconstitutional," continued Judge Kobes. "It targeted religious groups for differential treatment under the Human Rights Policy, while carving out exemptions and ignoring other violative groups with missions they presumably supported."
In April 2021 a federal appeal court ruled that Wayne State University in Detroit, Michigan had behaved unconstitutionally in de-registering IVCF for the same reasons.
The court decision in that case stated that it was "discriminatory" for the university to expect a Christian student organisation to appoint non-Christians into positions of leadership.
US federal judge rules university behaved unlawfully in de-registering Christian union
US Supreme Court votes to end "unfair" public aid ban on religious schools in Montana


Inspired by the Tea growers alliance, different bamboo furniture makers, growers, designers, researchers and bamboo enthusiasts have decided to form a Bamboo Alliance of Nepal.
The first meeting was held in Greenchwich Hotel Nepal, in which it was decided that there will be Six Core Groups representing different sectors and each group will be represented by one or two elected individual from the alliance. The responsibilities of the representatives are to gather all the people working in their line of product/ group of work and select a representative to sign the MoU.
It was also decided that Abari will represent the Research and Development sector.


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text:
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	<piece name="Pawn" color="Black" position="A1" />
	<piece name="Knight" color="Black" position="C2" />
	<piece name="Bishop" color="White" position="D3" />
	<piece name="Rook" color="White" position="B5" />
	<piece name="Queen" color="Black" position="A7" />
	<piece name="King" color="White" position="E4" />
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redpajama_set_name: RedPajamaGithub


The West Kelowna teen plays shortstop for the Vancouver (Washington) Patriots in the U18A division as well as for the TriCity Titans in U19A softball here in British Columbia.
It's her second year travelling to the U.S. to play softball, where Willier says competition is more fierce on the diamond.
"People take it more seriously when they go practice and go play games, so usually there are better players and more committed players," said Renay who was elected to captain her team in Vancouver, Wash., this summer.
"It makes me think that no matter where you come from, you could fit right in and people accept you."
On Tuesday, Renay will be one of 12 B.C. athletes to receive the Premier's Award for Indigenous Youth Excellence in Sport at an awards ceremony in Port Alberni, which honours youths' excellence in sport, leadership qualities, commitment to their education and roles in their communities both on and off the sports field.
Her photo and bio will also go into the B.C. Sports Hall of Fame this year.
Renay is originally from the Sucker Creek First Nation in Alberta.
Her father, Kevin, was left to raise Renay and her sister on his own, when their mother passed away when Renay was only two years old.
Kevin soon found healing by playing softball and discovered the community nature of the sport was good for his daughters as well, he said.
"They grew up around the ball field," said Kevin.
"We would go to tournaments and there would always be players and girlfriends and moms around who would help me with my girls while I played, and they would have their kids around so [my girls] would get to play, and I would get to play, and we spent every weekend like that from their little childhood."
The family eventually moved to West Kelowna, and Renay started to play softball in the Central Okanagan.
But last summer she sought to play against higher levels of competition in the U.S., and Renay and her father logged 10s of thousands of kilometres in their car travelling to tournaments in cities as far as San Diego.
"We joke around in the month of July we put 10,000 kilometres on the car in one month," he said.
Renay's play has already caught the attention of some U.S. college recruiters. It's the kind of attention she enjoys as she hopes to play Division 1 college softball.
"I like knowing that I have a way to get to college with something I love doing."


TGHI is dedicated to improving lives in low-income neighborhoods with programs for critical needs, better health, new skills, jobs, housing and economic stability. Since inception in 2000 TGHI has been fighting the effects of poverty in communities where 1 in 4 families battle poverty, illiteracy, drug dependency, HIV, delinquency, teen pregnancy, gangs, crime and hopelessness. The initial focus of the Health Initiative was to reduce HIV and substance abuse in the West Grove, South Miami, and Coral Gables, and to help residents find resources for critical living problems with a staff of Master's-level Counselors and Clinical Social Workers. Within a few years, the agency added programs to help families with education, teen violence, and social and life skills. Recently TGHI has added job training and placement for all ages in our CANTEEN Jobs Program, and our Passport Curriculum for Practical Skills. Plans are underway to replicate the Canteen Jobs Program and Passport Curriculum in more locations in Miami-Dade County.
TGHI esta dedicado a mejorar las personas que viven de bajo recursos en nuestros vencindarios. Con programas para las personas con nesecidades criticas y mejorar su salud y ayudarlos con trabajos, alojamiento y estabilidad economica.


Tissue specificity Natural killer cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Also detected in gamma-delta cells and CD8+ alpha-beta T-cells. Expressed in interferon-producing killer dendritic cells (IKDCs).
Background Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed cells by the immune system, and thus this protein and its ligands are therapeutic targets for the treatment of immune diseases and cancers. Read-through transcription exists between this gene and the upstream KLRC4 (killer cell lectin-like receptor subfamily C, member 4) family member in the same cluster.
Western Blot analysis of 3T3 cells with CD314 Polyclonal Antibody.


text:
Could Ownership Be A Part Of John Elway's New Contract?
We've been talking about the Broncos' ownership in comments the past two days, so it's only appropriate that this article arises from Nicki Jhabvala:
"(Elway) may be a unique situation because of the ownership challenges," [former agent Joel] Corry said. "One of the holdups might be him angling for some sort of ownership or a piece of the team."
Bowlen is still the owner of the team, but the Broncos have been placed in a family trust operated by three trustees: Ellis, team counsel Rich Slivka and Denver attorney Mary Kelly. The trust is intended to serve as the vehicle to hand controlling ownership to Bowlen's seven children. Each child will have equal stake as a beneficiary of the trust, but the trustees are tasked with appointing the ownership representative among the seven kids.
But consider the trustees also have the authority to sell the team in full and in part. Ellis, as president and CEO, has the power to extend Elway's contract. And Ellis and the other two trustees have the authority to push to give him a piece of the team — should that even be something they and Elway are considering.
Before you proceed to my comments beyond the fold, also refresh yourself by reading this excellent 2014 article from David Migoya on the subject.
What do I see as the big detail in Jhabvala's piece? I was not aware that Ellis and the other two trustees had the power to sell the team in part. From what I had inferred from Migoya's article, if the trustees authorized a sale, it was going to be for the entire team. But if the power to sell in part is in option, then that gives Ellis in particular much flexibility to negotiate a deal with Elway.
It's important to note that Jhabvala does not cite that ownership is in play, stating that "[i]t's unclear whether Elway is asking for a piece." So discussion of this is mainly relying on Corry, a highly respected former agent in the media. But since we've had our own speculation on the subject, this provides a good opportunity to merge the two.
Here's a review of some of the points in play discussed.
Does Elway have the assets to purchase even a small slice of the Broncos?
John Elway's net worth has been estimated by CheatSheet at $145 million. While that clearly makes him a 1 percenter, one needs to be well into the 0.01 percent to enter NFL ownership territory. If Forbes is correct about the Broncos' market value being $2.4 billion (that's a Carl Sagan B), everything that Elway has would only amount to 6% of the team.
Could Ellis give Elway a hometown discount with ownership? Does he even have the authority to do so under the trust? Would it even be legal given any possible tax consequences? Suffice to say, there are many questions about such a maneuver, and that's why the wisdom of lawyers are so valuable.
More questions: could Elway form some sort of ownership group with the Bowlen children that gives him the authority to be the controlling owner? Could he pull in external investors, as Migoya suggested? And if those external investors are wealthier than Elway, why would they want to play second fiddle to him when they might have a shot at controlling ownership on their own?
Any sale would have to be approved by the NFL…or would it?
All of the above ideas would ostensibly hinge on one important factor: any sale of a team has to meet NFL approval–or in other words, approval of the other owners who would be inducting one of their own into their exclusive fold.
The good news for Elway is that he should be someone that the NFL holds in high regard, as one of the greater players and executives in its history. His regard would likely rise with the presence of Ellis negotiating such a deal. Migoya guessed back in 2014 that the NFL might push for a change in two years, but here we are in the middle of 2017 with no such change. This may indicate that Ellis, who has been effectively acting as the Broncos' owner when it comes to official league matters for quite some time, has developed a good rapport with the other owners and with Roger Goodell, lessening any concern about the team's uncertain ownership state. Contrast this with the Titans, who Goodell has publicly criticized in several instances for not being in full compliance with NFL ownership rules after Bud Adams died.
Getting NFL approval is very important to ensure that good relations are established with any new ownership. But I'm curious (and once again, thoughts from the legal eagles here are appreciated) if this would hold up legally under antitrust law if someone wanted to push the limits. One of my fears has been a rogue billionaire swooping in to purchase the Broncos beyond league mechanisms, and then arguing in court that the NFL has no right to stop it. When Al Davis sued the league, it created decades of enmity between he and the rest of the league, with no recourse short of kicking the Raiders out, which of course didn't happen (although that would have been so sweet). I definitely do not want the Broncos to be seen in that kind of animosity.
If an ownership change involving Elway is in play, it would make sense if such a deal could not be finalized until the league's fall meeting, which takes place October 17-18 in New York.
The future of the Broncos' ownership is a really big deal that all fans need to pay keen attention to.
Regardless of whether it's Elway, a Bowlen child, or someone else, whoever does succeed Pat Bowlen (one of the best owners in NFL history that needs to be recognized as such) matters. Success in all professional sports starts at the top. A change in ownership can follow with a change in results on the field, for better or worse. In the NFL, the 49ers went from the elite franchise of the 1980s and 1990s to largely a laughingstock when Eddie DeBartolo, Jr. lost control of the team to the York family. In the NBA, James Dolan's ownership of the Knicks has been a repeated comedy of errors.
Broncos fans should all be hoping that they get an owner that continues Bowlen's winning culture–and also hope that they're not pining for Hank Scorpio to swoop in and pry ownership away to some slob at a nuclear plant that would be deemed to be better than the new boss. At least he could pretend to be a great Bronco…
Posted on July 14, 2017 July 14, 2017 Author NickCategories Uncategorized
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Toronto Wolfpack went into their home match knowing the win would claim them the League Leader's Shield in the Betfred Championship, and that's exactly what they did.
Paul Rowley's side showed a dominant performance over Sheffield Eagles with a 68-4 victory, which saw the side claim the Shield with 18 wins in 20.
That's their second trophy in just two years of existence, and the team will look to go one further and claim their spot in the Super League.
London Broncos' fight for a top four position continued as they travelled to France to face second-placed Toulouse.
The home-side had the advantage with just 10 minutes to play, but a try from Eddie Battye and a late penalty kick from Keiran Dixon saw the two teams share the spoils in a 20-20 draw.
At the rear end of the table, Rochdale Hornets snatched the victory from Stuart Littler's Swinton Lions following a last-minute try from Morgan Smith. Swinton had the lead for the entire game, but a charge down from the Warrington dual-registration player sees Rochdale go joint on points with Swinton at the bottom of the table.
In a weekend of late comebacks, Dewsbury Rams managed to claim the win over struggling Barrow Raiders, who have recently announced their financial difficulties, including a fundraiser page to see out the season. Lucas Walshaw scored the try in the 73rd minute, which saw the player claim the man of the match from the Dewsbury social media accounts.
In-form Halifax continued to impress the Championship and further claim their spot in the all-important top four following a victory over Featherstone Rovers, as Scott Murrell claimed man of the match with three try assists.
The two points sees Richard Marshall's side go on top of Rovers in the table to third spot, with Featherstone just one-point ahead of fifth-placed London.
Leigh Centurions also continued their push for a top-four place following a 30-12 victory over Batley Bulldogs at the Fox's Biscuits Stadium.
Kieron Purtill's side are now two-points behind Featherstone thanks to braces for Ilias Bergal and Harrison Hansen, plus further scores from Ryan Bailey and Ben Reynolds.


The BX940 enclosure is an integrated GNSS-Inertial engine delivering high accuracy GNSS, DGNSS positions in the most challenging environments powered by the BD940-INS. The unit is a robust navigation solution that has an environmentally sealed enclosure.
The Trimble BX940 packages a single BD940-INS receiver module in a rugged enclosure. The unit comes in an environmentally sealed enclosure that is very easy to install. The unit is rigorously tested to perform in harsh environmental conditions.
For all inquiries, please submit a request using our How to Buy submission form.


OPINION: Whatever Happened to the Machine That Turns Feces Into Water?
Earlier this year, I shared a video where I drank water made from feces. (My review: It was delicious.) Today the machine that produced the water, the Janicki Omni Processor – or JOP – is in Dakar, Senegal, as part of a pilot project that could ultimately save lives and reduce disease in poor countries.
You may recall that the JOP takes human waste and turns it into drinking water, electricity, and ash. (It is actually one of several Omni Processors being developed that treat human waste and produce something of value.) It's tempting to focus on the drinking water, for obvious reasons. But the goal is not to provide water. The goal is to dramatically improve sanitation for all the cities in poor countries.
Today at least 2 billion people use latrines that aren't properly drained, and diseases caused by poor sanitation kill some 700,000 children every year. Unfortunately, rich-world solutions aren't feasible in poor countries – they require too much expensive infrastructure. The idea behind every Omni Processor design is to solve this problem by making sanitation affordable for the poor.


"Fresh Off the Boat" showrunner Nahnatchka caravanserai will reunite with Randall Park and Ali Wong and form her attribute film directorial debut for Netflix's untitled romantic sport project leading Park and Wong. ruler is the governance creator and lord of ABC's "Fresh Off the Boat," which has complete its fourthly season. Park stars in the sitcom and Wong is presently authorship on the show.
AP Images is the world's largest postulation of historical and modern photos. AP Images provides instant access to AP's iconic editorial photos of today's breakage news, important person portraits by renowned Invision photographers, historical images across all genres, creative rights managed and royalty-free stock photography a microstock subscription or music tracks to round out a story, project or production. AP's Assignment and promotional material work is set to assist you with start-to-finish planning, execution and system for all of your promotional needs.
It is time for an inform on a proposal—about which I wrote two columns (the second of which is here) last summer—that seeks to carve California up into 3 separate states. Last week, Silicon Valley venture free enterprise Tim Draper, the dynamical organization behind the proposal, proclaimed that his organization had gathered more than 600,000 signatures from enrolled voters passim the state's 58 counties. That volume of signatures, if verified by the golden state intimate of State, would easily beat the figure of signatures required by territorial division law to put the point of reference on the statewide ballot this November.


text:
A new video for L.A. Noire
PS3, Xbox 360 [ Rockstar Games - Team Bondi ]
The Technology Behind LA Noire's Lifelike Performances
The latest title from Rockstar Games, L.A. Noire is a dark and violent detective thriller set in Los Angeles during the post-war years of the late 1940's. Players take the reins of newly minted detective Cole Phelps (Aaron Staton of Mad Men) as he solves gruesome and mind-bending cases, interrogates suspects, and rises through the ranks of the LAPD in a city where everyone has something to hide.
L.A. Noire is the first game ever to use a brand new technology called MotionScan which goes beyond traditional motion capture to put real actor's performances inside the game, creating a level of realism and immersion never before seen in a videogame. Using a special high definition, 32-camera rig to accurately scan and digitize an actor's facial performances, Motionscan captures every subtle emotional detail, allowing players to truly feel like a detective as they read the emotional behavior of every character in order to get to the truth.
LA Noire will be released for the Xbox and Playstation 3 in Spring 2011.
L.A. Noire is a dark and violent detective thriller set against the backdrop of Los Angeles in the post-war years of the late 1940s and delivered with Rockstar's signature attention to atmosphere and detail.
In L.A. Noire, players will take the reins of newly minted detective Cole Phelps (Aaron Staton of Mad Men) as he solves gruesome and mind-bending cases, interrogates suspects, and rises through the ranks of the LAPD.MotionScan L.A. Noire's Revolutionary Technology
The foundation of L.A. Noire is a brand new technology called MotionScan that enables us to capture and scan every nuance of a real actor's facial performances and put them right into the game itself. It provides a level of realism, detail, performance and emotion never seen before in a videogame, and brings them to life in a totally new way. This goes beyond the limited grid of data points delivered by traditional motion capture – these are the actual performances themselves, scanned and placed onto our digital characters. This marriage of gameplay and technology allows players for the first time ever to truly feel like a detective, reading the emotional behavior of every character. Furthermore, MotionScan lends itself perfectly to this type of game: one that focuses on characters and performances where everyone has something to hide.
Quick Facts About MotionScan
MotionScan is a new performance capture technology and alternative to traditional motion capture
MotionScan utilizes 32 high-definition cameras that completely surround the actor and capture the performance in 3D at 30 frames-per-second
MotionScan technology is provided by Depth Analysis, sister company to Team Bondi and part of a special partnership with Rockstar Games
Every character in L.A. Noire uses the MotionScan technology and over 400 actors were filmed making the game
L.A. Noire will be the first video game to ever utilize MotionScan technology
Images de LA Noire
Vidéo de LA Noire
Titre : LA Noire
Editeur : Rockstar Games
Studio : Team Bondi
Plateformes : PS3, Xbox 360
Votre avis sur LA Noire
LA Noire : dernières infos
17-11Bande-annonce officielle de L.A. Noire sur Nintendo Switch 17-094 nouvelles versions de L.A. Noire sera dispo le 14 novembre 11-111er trailer de L.A Noire Edition complète sur PC 11-06Announcing L.A. Noire Downloadable Content Details 11-05Square Enix annonce la distribution du Guide stratégique officiel français de L.A. Noire 11-02Vidéo de gameplay - 'Au fil des indices ' 11-01Rockstar Games Announces Release Dates for L.A. Noire 11-01The Art of Interrogation: New L.A. Noire Screens 10-12A Special Look Behind the Scenes of L.A. Noire - Coming this Thursday, December 16th 10-12New Screenshots of L.A. Noire: Crime Scenes, Lineups and More 10-11Watch the first proper reveal of L.A. Noire in action now Plus d'informations sur LA Noire


There are a ton of games that are part of the Microsoft Spring Sale and while majority are worthy of being added to your Xbox One collection of titles, we narrowed down the best games that are super cheap right now that you can't miss out on. As part of the sale, there are 95 Xbox One games available for $10 or under.
Outside of the digital deals on the Xbox Store, there are also discounts of up to $100 to be had on select Xbox One consoles, $5 off a Design Lab Xbox Wireless Controller, deals on Turtle Beach Headsets and more besides. Discounts range from minor to fairly substantial, with the best prices reserved for Xbox Live Gold subscribers. New Xbox Live Gold members can sign up for just $1. They receive 1,000 Apex Legends coins on top of that. Remember, the deals in the store and gaming websites don't usually include the extra ten percent that Gold members will receive.
Microsoft is going all out on April, we're hoping that Sony comes up with its own spring discounts to give PS4 owners some good deals.
Also, the Spring Sale ends on April 22, so be sure to grab these titles while you can. What do you think about the Spring Sale?


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Q: How do I compile the string value from angular's ui-ace to actual HTML What i am trying to figured out is how to compile the string values from Ace editor. As you can see i get the strings with out compiling. I appreciate all the help. Thanks

   <textarea id="ace_document"> {{aceDocumentValue}}</textarea>

 app.controller('AceCtrl', function ($scope) {
    // select
      $scope.modes = ['CoffeeScript','ColdFusion'];
      $scope.mode = $scope.modes[0];

     $scope.aceLoaded = function(_editor) {
     mode: $scope.mode.toLowerCase(),
    $scope.aceSession = _editor.getSession();
     _editor.setTheme("ace/theme/monokai");

      // options
           _editor.setOptions({
            showGutter: true,
            showPrintMargin: false,
            fontSize: '14px',
            fontFamily: 'menlo'
           });
           // HACK to have the ace instance in the scope...
          $scope.modeChanged = function () {
            _editor.getSession().setMode("ace/mode/" + $scope.mode.toLowerCase());
          };
    };
    $scope.aceChanged = function () {
        $scope.aceDocumentValue = $scope.aceSession.view.contents().getValue();
    };

});

A: You can do that with a custom directive and use $compile to compile it to actual HTML.
See the documentation on directives: https://docs.angularjs.org/guide/directive and on $compile: https://docs.angularjs.org/api/ng/service/$compile
angular.module('app').directive('compiler', [
    '$compile',
    function ($compile) {
        return {
            restrict: 'E',
            replace: true,
            link: function (scope, element, attributes) {
                scope.$watch(attributes.html, function (html) {
                    element.html(html);
                    $compile(element.contents())(scope);
                });
            }
        };
    }
]);

Put the new compiler element into your template:

<compiler html="aceDocumentValue"></compiler>

In your controller get the value and assign it to your scope:
angular.module('app').controller('rootController', [
    '$scope',
    function ($scope) {
        $scope.aceLoaded = function(_editor) {
            $scope.aceSession = _editor.getSession();
        };
        $scope.aceChanged = function () {
            $scope.aceDocumentValue = $scope.aceSession.getDocument().getValue();
        };
    }
]);

Here's a working example on Plunker: http://plnkr.co/edit/pHhDX7RBR1YmYbTG8PXT?p=preview

redpajama_set_name: RedPajamaStackExchange


Fabre, E, Sfihi‑Loualia G, Pourcelot M, Coddeville B, Krzewinski F, Bouckaert J, Maes E, Hurtaux T, Dubois R, Fradin C et al.. 2014. Characterization of the recombinant Candida albicans β-1,2-mannosyltransferase that initiates the β-mannosylation of cell wall phosphopeptidomannan. Biochemical Journal. 457601776365230106066(2):347-360.
Pourcelot, M, Cattiaux L, Sfihi-Loualia G, Fabre E, Krzewinski F, Fradin C, Poulain D, Delplace F, Guérardel Y, Mallet J-M. 2013. Mantyl tagged oligo α (1 → 2) mannosides as Candida albicans β-mannosyl transferases substrates: a comparison between synthetic strategies. RSC Advances. 3(44):22560.


Well to say that Suicide Squad was a disappointment would be an understatement. Honestly it has nothing to do with the acting. The acting quality and caliber of actors were great. The special effects were also amazing. The only thing that killed this movie and made it terrible was the plot and editing of the film. There was too much backstory and not enough story to make the movie worth watching. Several other things made it terrible such as the underdevelopment of characters and leaving them for pure comical purposes….


Mums clever Kmart sandwich maker trick is taking the internet by surprise!
The sandwich maker which retails for just $7.50 at Kmart has shocked the country after Kmart Mum, Kelly, revealed that she'd recently, cooked a chocolate dessert using the appliance.
Sharing pics of her chocolate cakes, she wrote: 'I know I'm a bit late to the party but I finally got my chance to make chocolate Brevilles with the $7.50 Kmart Sandwich Maker,' I used the 79 cent Coles cake mix. I'm gonna try a brownie mix next!
Kelly added she cooked the mix for about 3 to 5 minutes, depending on 'if you want them a bit gooey in the middle'. Love it!
OMG! How have we not thought of this before. Yum!
Check out some of the amazing creations in the Kmart pie maker HERE.
What a fantastic idea! I've used a jaffle iron on a coal fire for cooking dampers but never thought of this option. Even heating and interesting shapes. Brilliant!
This is quick and easy and I am guessing pretty delicious too. Sounds similiar to cake in a cup. great as a snack.
This is such a great idea for kids on a rainy day, no risk of burns & minimal clean up. Will certainly be trying this!
It's not something I would do but still a great, novel idea.
Ok, cakes in 5 minuts? I'm in!!
WOW is there anything this amazing machine can't do??
Bet the uni kids are going to Kmart in droves!!
I wonder if this would work well with other types of cakes. Like ones with fruit in them etc.
Great for a quick snack – beats making a batch of scones when visitors come over.
I'm not to sure about this – I think if i'm going to bother to make a cake or muffins I will do it properly.
Great hack but I think I like the traditional shaped cupcake. But they'd fit well in a lunch box!


Square Enix Forums > Games > Tomb Raider Series > Tomb Raider Classic > Tomb Raider - Level Editor Forum > what am i doing wrong??????????
View Full Version : what am i doing wrong??????????
so as the title reads...........what am i doing wrong???????????????????????????????????
You use the wrong program to change the sounds. It seems Core Design used Sound Forge 4.0 and only this program seems to work correctly (maybe some others too).


text:
An Analysis of Infectious Failures in Acute Cholangitis
Jesse Thompson, Robert S. Bennion, Henry A. Pitt
To determine the factors responsible for therapeutic failures in acute cholangitis, a series of 127 patients was analyzed. There were 64 females and 63 males whose mean age was 57.2 years. Ninetyfour (74.0%) of these patients were clinically cured with initial measures, whereas 33 patients (26%) failed initial therapy for an infectious reason. No differences were observed between the two groups in regard to age and gender. However, more patients in the group that failed had a malignant cause for their bile duct obstruction (72.7% vs. 42.6%, p < 0.01) and had a pretreatment positive blood culture (45.5% vs. 13.8%, p < 0.01). Patients who failed had a higher mean total bilirubin level (9.7 mg/dl vs. 5.5 mg/dl, p < 0.005) and more of them had a level greater than 2.2 mg/dl (97% vs. 69.9%, p < 0.001). Also, more bile cultures were initially positive (93.9% vs. 76.6%, p < 0.05) and more organisms were isolated per culture (3.88 vs. 2.86, p < 0.03) in the patients who failed. In addition, more patients failed who had two or more organisms in the bile (33% vs. 8.3%, p < 0.02). Patients in whom Candida, or any panresistant organism was isolated also tended to fail. Multivariant analysis showed that malignancy, bacteremia, bilirubin > 2.2 mg/dl, > 2 organisms in the bile and a panresistant organism were the best predictors of treatment failure with a serum bilirubin level > 2.2 mg/dl being the variable that increases a patient's log-odds ratio of failure the greatest. In conclusion, patients with acute cholangitis who have an increased chance to fail initial therapy can be identified, and treatment altered accordingly.
HPB Surgery
https://doi.org/10.1155/1994/73139
Cholangitis
biliary antibiotics
biliary infection
10.1155/1994/73139
Dive into the research topics of 'An Analysis of Infectious Failures in Acute Cholangitis'. Together they form a unique fingerprint.
Cholangitis Medicine & Life Sciences 100%
Cholestasis Medicine & Life Sciences 15%
Bile Medicine & Life Sciences 13%
Bilirubin Medicine & Life Sciences 13%
Treatment Failure Medicine & Life Sciences 13%
Odds Ratio Medicine & Life Sciences 8%
Serum Medicine & Life Sciences 6%
Thompson, J., Bennion, R. S., & Pitt, H. A. (1994). An Analysis of Infectious Failures in Acute Cholangitis. HPB Surgery, 8(2), 139-145. https://doi.org/10.1155/1994/73139
An Analysis of Infectious Failures in Acute Cholangitis. / Thompson, Jesse; Bennion, Robert S.; Pitt, Henry A.
In: HPB Surgery, Vol. 8, No. 2, 1994, p. 139-145.
Thompson, J, Bennion, RS & Pitt, HA 1994, 'An Analysis of Infectious Failures in Acute Cholangitis', HPB Surgery, vol. 8, no. 2, pp. 139-145. https://doi.org/10.1155/1994/73139
Thompson J, Bennion RS, Pitt HA. An Analysis of Infectious Failures in Acute Cholangitis. HPB Surgery. 1994;8(2):139-145. https://doi.org/10.1155/1994/73139
Thompson, Jesse ; Bennion, Robert S. ; Pitt, Henry A. / An Analysis of Infectious Failures in Acute Cholangitis. In: HPB Surgery. 1994 ; Vol. 8, No. 2. pp. 139-145.
@article{9d0617ca32c7415eae0210d5f688b930,
title = "An Analysis of Infectious Failures in Acute Cholangitis",
abstract = "To determine the factors responsible for therapeutic failures in acute cholangitis, a series of 127 patients was analyzed. There were 64 females and 63 males whose mean age was 57.2 years. Ninetyfour (74.0%) of these patients were clinically cured with initial measures, whereas 33 patients (26%) failed initial therapy for an infectious reason. No differences were observed between the two groups in regard to age and gender. However, more patients in the group that failed had a malignant cause for their bile duct obstruction (72.7% vs. 42.6%, p < 0.01) and had a pretreatment positive blood culture (45.5% vs. 13.8%, p < 0.01). Patients who failed had a higher mean total bilirubin level (9.7 mg/dl vs. 5.5 mg/dl, p < 0.005) and more of them had a level greater than 2.2 mg/dl (97% vs. 69.9%, p < 0.001). Also, more bile cultures were initially positive (93.9% vs. 76.6%, p < 0.05) and more organisms were isolated per culture (3.88 vs. 2.86, p < 0.03) in the patients who failed. In addition, more patients failed who had two or more organisms in the bile (33% vs. 8.3%, p < 0.02). Patients in whom Candida, or any panresistant organism was isolated also tended to fail. Multivariant analysis showed that malignancy, bacteremia, bilirubin > 2.2 mg/dl, > 2 organisms in the bile and a panresistant organism were the best predictors of treatment failure with a serum bilirubin level > 2.2 mg/dl being the variable that increases a patient's log-odds ratio of failure the greatest. In conclusion, patients with acute cholangitis who have an increased chance to fail initial therapy can be identified, and treatment altered accordingly.",
keywords = "Cholangitis, biliary antibiotics, biliary infection",
author = "Jesse Thompson and Bennion, {Robert S.} and Pitt, {Henry A.}",
doi = "10.1155/1994/73139",
journal = "HPB Surgery",
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T1 - An Analysis of Infectious Failures in Acute Cholangitis
AU - Thompson, Jesse
AU - Bennion, Robert S.
AU - Pitt, Henry A.
N2 - To determine the factors responsible for therapeutic failures in acute cholangitis, a series of 127 patients was analyzed. There were 64 females and 63 males whose mean age was 57.2 years. Ninetyfour (74.0%) of these patients were clinically cured with initial measures, whereas 33 patients (26%) failed initial therapy for an infectious reason. No differences were observed between the two groups in regard to age and gender. However, more patients in the group that failed had a malignant cause for their bile duct obstruction (72.7% vs. 42.6%, p < 0.01) and had a pretreatment positive blood culture (45.5% vs. 13.8%, p < 0.01). Patients who failed had a higher mean total bilirubin level (9.7 mg/dl vs. 5.5 mg/dl, p < 0.005) and more of them had a level greater than 2.2 mg/dl (97% vs. 69.9%, p < 0.001). Also, more bile cultures were initially positive (93.9% vs. 76.6%, p < 0.05) and more organisms were isolated per culture (3.88 vs. 2.86, p < 0.03) in the patients who failed. In addition, more patients failed who had two or more organisms in the bile (33% vs. 8.3%, p < 0.02). Patients in whom Candida, or any panresistant organism was isolated also tended to fail. Multivariant analysis showed that malignancy, bacteremia, bilirubin > 2.2 mg/dl, > 2 organisms in the bile and a panresistant organism were the best predictors of treatment failure with a serum bilirubin level > 2.2 mg/dl being the variable that increases a patient's log-odds ratio of failure the greatest. In conclusion, patients with acute cholangitis who have an increased chance to fail initial therapy can be identified, and treatment altered accordingly.
AB - To determine the factors responsible for therapeutic failures in acute cholangitis, a series of 127 patients was analyzed. There were 64 females and 63 males whose mean age was 57.2 years. Ninetyfour (74.0%) of these patients were clinically cured with initial measures, whereas 33 patients (26%) failed initial therapy for an infectious reason. No differences were observed between the two groups in regard to age and gender. However, more patients in the group that failed had a malignant cause for their bile duct obstruction (72.7% vs. 42.6%, p < 0.01) and had a pretreatment positive blood culture (45.5% vs. 13.8%, p < 0.01). Patients who failed had a higher mean total bilirubin level (9.7 mg/dl vs. 5.5 mg/dl, p < 0.005) and more of them had a level greater than 2.2 mg/dl (97% vs. 69.9%, p < 0.001). Also, more bile cultures were initially positive (93.9% vs. 76.6%, p < 0.05) and more organisms were isolated per culture (3.88 vs. 2.86, p < 0.03) in the patients who failed. In addition, more patients failed who had two or more organisms in the bile (33% vs. 8.3%, p < 0.02). Patients in whom Candida, or any panresistant organism was isolated also tended to fail. Multivariant analysis showed that malignancy, bacteremia, bilirubin > 2.2 mg/dl, > 2 organisms in the bile and a panresistant organism were the best predictors of treatment failure with a serum bilirubin level > 2.2 mg/dl being the variable that increases a patient's log-odds ratio of failure the greatest. In conclusion, patients with acute cholangitis who have an increased chance to fail initial therapy can be identified, and treatment altered accordingly.
KW - Cholangitis
KW - biliary antibiotics
KW - biliary infection
U2 - 10.1155/1994/73139
DO - 10.1155/1994/73139
JO - HPB Surgery
JF - HPB Surgery


text:
Home Information 11 Great Examples of Wearable Technology
11 Great Examples of Wearable Technology
Ever since the Caped Crusader first donned his famous utility belt, the idea of wearable gadgets has captured the imagination. Of course wearable technology is nothing new and even the earliest wristwatches and spectacles fall into this category but today's technological advances and miniaturisation have opened up an immense range of possible future applications limited it seems only by our imagination.
The Smart Watch
The Apple Watch is probably the most hyped example of the smart watch but is certainly not the first nor the most advanced. Despite huge pre-launch publicity, its sales have been slow and by Apple's standards it must be regarded as something of a flop. Its fitness app gives such information as how long you have been sitting for and of course it works perfectly well as a watch (but so does a bottom of the range Casio!). Its appearance may impress a twelve year old gadget fan but most mature adults will find it rather tacky. The main problem is that it really only functions as an iPhone accessory making it about as interesting as a TV remote control.
Fitness Bands such as Fitbit and Jawbone are hugely popular as their wearers seem to believe that simply by wearing them they are following a life changing fitness routine. Their measurement parameters are fairly basic but give some indication as to an individual's fitness levels. Serious athletes rely on more sophisticated monitoring in order to optimise training techniques and achieve the best possible performance.
Contactless Payment Devices
This technology has been around for a long time now but its take-up has been slow. For most users it seems like gadgetry for the sake of it with no particular advantages but for retailers and banks it represents a great way to get money with no need for any expensive human input. Perhaps unsurprisingly, Barclays are working on providing customers with smart key fobs, stickers and wristbands.
When Katy Perry wore a Cute Circuit LED illuminated dress in 2010, the idea of wearable technology in fashion really took off. Smart textiles are now available capable of displaying changing patterns, colours and even tweets! It may simply be a gimmick but has huge sales potential.
Following on from the above, smart fabrics have a significant future in the design of military uniforms. Although we are unlikely to see our armed forces going into action wearing Katy Perry dresses, military uniforms will certainly incorporate sophisticated circuitry to power all kinds of equipment. The advent of ultra-thin flexible batteries with solar and kinetic charging will add to the smart uniform's capabilities.
Smart Jeans
Anyone who has ever wanted to control a TV or laptop simply by rubbing their thigh will welcome the arrival of patches of intelligent textiles developed to be incorporated in denim jeans. This may be in the form of a touchpad or even low power radar which can detect hand gestures made close by. The only question is why?
Homing Sunglasses
Wearable technology does not have to be cutting edge and Tzukuri Bluetooth sunglasses are designed never to be lost. This seems like a slightly updated version of those key rings that bleep when you whistle.
Smart Jewellery
Many people find that an incoming message notification is rather vulgar when announced by a bleeping or vibrating phone so the "Ringly" by Christina Mercando is simply a highly attractive gemstone ring which flashes to herald the announcement.
The term "Smart Glasses" is really a vast understatement as these devices, such as Google Glasses, are in reality head worn computers. Although originally launched as consumer devices, their popularity seems to have suffered due to their generally unacceptable appearance. People feel uneasy when dealing with what simply looks like a head-cam and the geeky looks of their users soon gave rise to the name "Glass-holes". The emphasis has now changed to business use and, especially in medicine, this could represent a tremendous advantage.
The Future?
The future applications of wearable technology seem almost endless but, in true Darwinian style, many will fall by the wayside while others gain in popularity and strength. Medical applications will become ever more sophisticated with such devices as the Google smart contact lens which monitors glucose levels and, as monitoring systems continue to advance, software developers such as FirstApp provide the number-crunching with mobile healthcare apps and clinical trials apps with particular emphasis on iOS, Windows and Android platforms. The fickle world of fashion is more difficult to predict but current estimates suggest that around 26 million smart garments will be sold during 2016. Suddenly Batman's utility belt is looking decidedly old-hat!
11 Great Examples of Wearable Technology Reviewed by Shubham ~NeO~ on August 11, 2015 Rating: 5
Tags : Information


text:
Smaller Is Better: Why Finite Number Systems Pack More Punch
Abstractions blog
Recent progress on the "sum product" problem recalls a celebrated mathematical result that revealed the power of miniature number systems.
Clock arithmetic describes any finite number system that loops back upon itself.
liseykina
Kevin Hartnett
Abstractions blogmathematicsnumber theoryAll topics
It's one thing to turn a cartwheel in an open field. It's another to manage it in a tight space like a bathtub. And that, in a way, is the spirit of one of the most important results in number theory over the past two decades.
The result has to do with the "sum-product problem," which I wrote about last week. It asks you to take any set of numbers and arrange them in a square grid, then fill in the grid with either the sums or the products of the crosswise pairs.
The sum-product problem states that the number of distinct sums or products will always be close to N2 (where N stands for the number of numbers used to make your grid).
The sum-product problem that I wrote about uses any set of real numbers to generate the grid. You can also restrict the problem to use unique number systems that are smaller and more constrained than the reals. These self-contained number systems are called "finite fields."
In mathematics, a "field" is any number system in which you can carry out the four basic operations of arithmetic: addition, subtraction, multiplication and division. The real numbers form a field. You can perform those operations on any two real numbers and the outcome is a third real number. Or, put another way, the arithmetic of the real numbers never yields a number outside the real numbers.
The integers — all the positive and negative counting numbers — don't form a field. Yes, you can add, subtract and multiply any two integers to produce a third integer. But divide 3 by 2 and you'll get 1½, which isn't an integer.
A "finite" field is a number system in which the number of numbers is finite. There are different kinds of finite fields, but the simplest one has to do with what's called "modular" or "clock" arithmetic. In modular arithmetic, when you get to the end of your finite list of numbers, you just loop back to the beginning, as if you were counting numbers around the face of a clock. For example, if you go to a party at 7 p.m. and get back home six hours later, you'll return at 1 a.m. More formally, 7 plus 6 in the base-12 modular number system equals 1.
(The 12 numbers on the clock don't actually form a field, and the reason why has to do with one of the most critical features of number theory: Modular number systems form fields only when they're comprised of a prime number of elements. In modular number systems with a nonprime number of elements, like the 12-digit clock, you end up in weird situations where the product of two nonzero numbers is zero. For example, 6 × 4 = 24, which equals 0 in the base-12 number system. This leads to other consequences that cause division to break down. But in a modular number system with a prime number of elements, two nonzero numbers never multiply to zero.)
Finite fields have been the setting for many celebrated results in mathematics. As self-contained arithmetic worlds, they contain a rich structure that mathematicians can exploit to solve problems related to everything from prime numbers to patterns in the solutions to polynomial equations.
In 2003, the mathematicians Jean Bourgain, Nets Katz and Terry Tao became the first mathematicians to make any progress on the sum-product problem over finite fields. They proved that either the number of distinct sums or the number of distinct products must be at least ever-so-slightly larger than the size of the set used to generate the sum and product grids. The statement was modest in size but momentous in significance.
Jean Bourgain (above), Nets Katz and Terry Tao proved a milestone connection between addition and multiplication.
Jean Bourgain, Nets Katz and Terry Tao (from left) proved a milestone connection between addition and multiplication.
George M. Bergman, Berkeley (Bourgain); Caltech (Katz); Reed Hutchinson/UCLA (Tao)
"It was the slightest thing we could get, but the point of it was it was the first result of its kind," said Katz, who is now at the California Institute of Technology.
The authors of the paper were a powerhouse team: Katz is a highly respected number theorist, and Bourgain and Tao are regarded as among the top mathematicians of their generations. Bourgain, who died of cancer in December at the age of 64, was the driving force behind the proof. Several years previously he'd solved a different kind of sum-product problem. When he turned to the finite-field version, he had a fairly clear idea of how to pursue a proof, but he brought in Katz and Tao for help understanding all the implications of his intended method.
"Basically Bourgain knew how to do it and wanted our help because he wanted to write out some of the applications of [his approach]," said Katz.
Since 2003 other mathematicians have improved on the trio's result by establishing that the number of distinct sums or products has to be even larger than what those three were able to guarantee. Mathematicians have also applied techniques from their proof to entirely different questions in math, including the study of objects called expander graphs and questions about polynomials and prime numbers.
Finite fields, which you can hold in your hand, might seem to be a less ambitious setting for the sum-product problem than the real numbers. But in fact, the question has much greater depth in the finite-field case, and far more implications for the rest of mathematics.
The reason is that it's much harder for the sum-product phenomenon to be true for finite fields than for real numbers. The original formulation of the problem predicted that any set of numbers will produce sum and product grids with many more distinct entries than the size of the set itself. Perhaps that's not a stunning statement when considered among the real numbers, which go on forever. But to be true in finite fields, where there's barely any room to move? That's like pulling off a cartwheel in a bathtub.
"The reals are an infinite set, and there's lots and lots of room to grow. But in a finite field there's only a very limited space to grow, so when you get a guarantee that some of that growth will happen, it's kind of a stronger statement," said Katz.
Artificial Intelligence Finds Ancient 'Ghosts' in Modern DNA


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The Hon. Steve Leben
Kansas Court of Appeals
University of Kansas, B.S., journalism
University of Kansas School of Law, J.D.
Steve Leben is a judge on the Kansas Court of Appeals, where he has served since 2007. Before that, he was a general-jurisdiction trial judge from 1993 to 2007 and practiced law in the Kansas City area from 1982 to 1993.
He teaches as an adjunct professor at the University of Kansas School of Law. He has taught Legislation and Statutory Interpretation regularly since 2007 and more recently has added an Evidence class.
Leben is a past president of the American Judges Association and edited its national journal, Court Review, from 1998 through 2017. He received the National Center for State Courts' William H. Rehnquist Award for Judicial Excellence, the National Center's highest award for a judge, in 2014 in recognition of his national work to improve procedural fairness in America's courts. Leben is a cofounder of the website, ProceduralFairness.com, devoted to providing resources on procedural justice for courts and law-enforcement personnel.
Civil Practice & Procedure (Litigation)


KANSAS CITY, Kan (Reuters) - A judge has blocked a Kansas law that would stop federal family planning money from going to Planned Parenthood, officials confirmed on Monday.
District Judge J. Thomas Marten granted a preliminary injunction in favor of the reproductive health organization, which had sued seeking to block implementation of the amendment cutting its funding.
Planned Parenthood of Kansas and Mid-Missouri had said the law stops federal money for cancer screenings, breast exams and birth control for low-income patients'.
Kansas plans to appeal the decision.
"It appears that the Court declared a duly-enacted Kansas statute unconstitutional without engaging in the fact-finding one would expect before reaching such a conclusion," said Kansas Attorney General Derek Schmidt, in a statement.
Planned Parenthood claimed that the law restricted Kansans' access to health care.
"Ensuring every patient continues to receive affordable family planning services and basic preventive health care, without long-term interruption, remains our primary concern," said Peter Brownlie, president and CEO of Planned Parenthood of Kansas and Mid-Missouri, in a statement.
A similar law cutting Medicaid dollars for Planned Parenthood in Indiana was blocked by a federal judge there.
Anti-abortion activists have targeted Planned Parenthood because it provides abortion services, although federal law prohibits the organization from using federal money for abortions.
Dr. Robert Moser, secretary for Kansas Department of Health and Environment, said in a statement that federal money was not intended as an "entitlement program" for Planned Parenthood.
The law affected $330,000 in funding for Planned Parenthood clinics in Wichita and Hays, according to spokeswoman Sarah Gillooly.


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AMG kan syfta på

 AMG – ett amerikanskt företag, se All Media Guide
 AMG – IATA:s flygplatskod för en flygplats i Papua Nya Guinea, se  Amboin flygplats
 Mercedes-AMG – ett dotterbolag till Mercedes-Benz


Following a narrow win over Philippines, Paulo Bento has urged South Korea to press on against Kyrgyzstan.
Mehdi Taremi scored twice as Iran battered Yemen 5-0 in the war-torn country's Asian Cup debut on Monday to fire an ominous warning to their title rivals.
A spectacular goalkeeping blunder helped Marcello Lippi's China avoid a humiliating defeat as they came from behind to narrowly beat minnows Kyrgyzstan 2-1 at the Asian Cup on Monday.
China's 2019 Asian Cup campaign could be the last challenge of a glittering coaching career for Marcello Lippi.
Muslim-majority Kyrgyzstan on Monday cancelled an international football match with Myanmar over "a potential terror act", as fears grow for the Southeast Asian country's Rohingya Muslims.
India was pitted against Kyrgyzstan, Myanmar and Macau when the draw for the final round of qualifying for the 2019 AFC Asian Cup took place Monday.
Tim Cahill scored his 42nd international goal as Australia turned on the sparkle to fuel their World Cup qualifying hopes with a 3-0 win over Kyrgyzstan in Canberra on Thursday.
The Socceroos will be without defender Matthew Spiranovic for Australia's upcoming World Cup qualifiers against Kyrgyzstan and Bangladesh, officials said on Monday.
The Socceroos have booked their flights for a World Cup tie in Dhaka which was thrown into doubt by the cancellation of an Australian cricket tour over security fears, Bangladesh's football federation said Wednesday.
The Socceroos received a boost Wednesday with captain Mile Jedinak and goalkeeper Mat Ryan declared fit for Australia's World Cup qualifiers against Kyrgyzstan and Bangladesh next month.


Cigarette Smoke vs. Vapor Smoke – What's the Difference?
You should never judge a book by its cover – or in this case, a smoker by the white/grey cloud coming out of his or her mouth. Even to a veteran vapor smoker, sometimes it's easy to mistake a harmless cloud of e-cig vapor for a haze of cigarette smoke.
Especially if you are relatively new to vapor smoking, you may be asking yourself what is the difference between the smoke produced by a cigarette and the vapor generated by an e-cig. They look so similar – so how different can they really be, right?
According to the American Cancer Society, cigarette smoke contains over 7,000 chemicals. Out of these substances, approximately 70 are considered carcinogenic, including cyanide, benzyne and ammonia. Nitrogen oxide and carbon monoxide are two poisonous gases that are also in traditional cigarette smoke, as well as tar.
It has also been proven that smoke may contain radioactive materials depending on the soil and fertilizer used to grow the tobacco leaves. These radioactive materials can build up in the smokers' lungs, causing significant harm. Smoking has been linked to 30 percent of all cancer-related deaths.
In other words, cigarette smoke is ugly inside and out.
Vapor, on the other hand, has more in common with a cloud or steam than with cigarette smoke. When you have a pot of water on the stove and heat it, the water vaporizes and turns into steam. This is the best way to describe how e-cig vapor clouds are produced. The atomizer coil superheats the e-liquid mixture (comprised of mostly water, flavoring, nicotine and a PG/VG blend), which turns it into an inhalable flavored vapor. Your body absorbs the nicotine and flavoring, and the remaining water vapor is exhaled in the form of a cloud.
No odor, no toxins – just a slightly sweet-smelling vapor cloud.
Also absent from vapor smoke is carbon monoxide, carbon dioxide and the combustion process that is present in smoking, which makes e-cigs a much safer alternative. With vapor smoking, there is no fire so it 100% ash and smoke-free!
If you haven't already, we invite you to consider choosing vapor smoking as the smarter alternative to traditional smoking. Come enjoy the benefits of smoking without all of the smoke, smell and hassle!
Browse our site to learn more about how to customize your e-cigs for a truly epic vaping experience.
Vaping: Less Addictive than Tobacco?


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Home › Sport › Football › Scottish › Rangers
Steven Davis: Rangers set to make January swoop to bring back Northern Ireland captain
Back to the future: Davis played for Rangers from 2008-12
By Laure James
October 31 2018 7:57 AM
Rangers are poised to swoop for Steven Davis in January, following months of speculation linking the Northern Ireland captain to his former club.
https://www.belfasttelegraph.co.uk/sport/football/scottish/rangers/steven-davis-rangers-set-to-make-january-swoop-to-bring-back-northern-ireland-captain-37477098.html
https://www.belfasttelegraph.co.uk/sport/football/scottish/rangers/190ea/37477097.ece/AUTOCROP/h342/2018-10-31_spo_45349900_I1.JPG
The Southampton midfielder quit Ibrox in a move to St Mary's in 2012 with the aim of reviving his career, yet now is looking north of the border for regular game time - starting with a loan move.
Davis has been repeatedly linked with a return to his boyhood club, which he was careful never once to close the door on, yet persevered with the dream of reigniting his Premier League career.
The 33-year old has, however, become increasingly frustrated with a lack of game time in the English top flight this season, and is yet to start in a league fixture.
In the last campaign, Davis had better luck, playing the number 10 role in a three-man midfield, yet boss Mark Hughes now deploys two defensively-minded central midfielders in Oriol Romeu and Mario Lemina, leaving the Northern Ireland skipper frozen out.
The Gers were keen on securing his return in the summer transfer window, but Hughes couldn't be persuaded to strike a deal.
The Belfast Telegraph now understands plans are under way to bring drifting Davis in under a loan agreement at first, with the option to sign him permanently.
It comes after the creative player's persistent trouble with hamstring and achilles injuries snuffed out an automatic one-year extension on his contract, sparking Rangers into action.
Davis racked up over 200 appearances with Rangers in his four seasons with the club, helping guide them to a Uefa Cup Final in 2008 after he was loaned from Fulham.
Thereafter he became a firm favourite, going on to win three league championships, two Scottish Cups and three League Cups.
Gers boss Steven Gerrard will hope his experience can help sustain a title challenge in the second half of the season, alongside international team-mates Kyle Lafferty and Gareth McAuley.
Gers have little margin for error, says McAllister
By Gavin McCafferty Rangers need to be "pretty perfect" for the rest of the Ladbrokes Premiership campaign as they attempt to end Celtic's long title reign, admits assistant manager Gary McAllister.
Steven Gerrard blasts eight Rangers 'passengers' after defeat to Hearts
By Andy Newport Steven Gerrard admits he has never seen Rangers play worse in his 100 games in charge than they did at Tynecastle as he warned a repeat display will kill off their title hopes.
Flanagan eager to secure new Gers contract
By Andy Newport Rangers defender Jon Flanagan insists he is ready to fight for his Ibrox future.
Defoe goal sees off St Mirren as Rangers keep pressure on Celtic
Jermain Defoe's 16th goal of the season saw Rangers navigate a way past stubborn St Mirren's roadblock tactics to claim a hard-fought 1-0 win.
Belfast bar fined £1k for failing to prevent smoking in beer garden Northern Ireland
Pictured: Car plunges down embankment at Northern Ireland beach New Articles
Dad of McGinley children found dead in Co Dublin home urges parents to... Republic of Ireland
Seamus Mallon's Protestant neighbours 'played major role in funeral' Northern Ireland
Sarah Caden: Prince Harry needs to calm down if he wants a quieter future Comment