text:
Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: A polymerase chain reaction-based pilot study
Alia Albawardi, M. Ruhul Quddus, Shamsa Al Awar, Saeeda Almarzooqi
Background: The incidence of abnormal cervical smears in the United Arab Emirates (UAE) is 3.6%. Data regarding specific high-risk HPV (hrHPV) genotypes are insufficient. Identification of hrHPV subtypes is essential to allow formulating effective vaccination strategies. Methods: A total of 75 archival cervical cone biopsies with HSIL or higher lesions (2012-2016) were retrieved from a tertiary hospital, including HSIL (n = 70), adenocarcinoma in-situ (n = 1) and squamous cell carcinoma (n = 4). Five tissue sections (10-μ-thick each) were cut and DNA extracted using the QIAamp DNA FFPE Tissue Kit. GenomeMeTM's GeneNavTM HPV One qPCR Kit was used for specific detection of HPV 16 and 18; and non-16/18 samples were typed by GenomeMeTM's GeneNavTM HPV Genotyping qPCR Kit. Results: Median age was 34 years (range 19-58) with 70% UAE Nationals. hrHPV detected were 16, 18, 31, 33, 35, 39, 45, 51, 52, 58, 59, 66 & 68. hrHPV testing was negative in 12% of cases. Most common types were HPV 16 (49%), HPV 31 (20%) and HPV 18 (6.6%). hrHPV 16 and/or 18 represented 56% and rare subtypes 32%. Co-infection was present in 16%. Eight cases had two-viral subtype infections and 4 cases had 3 subtype infections. Multi-viral HPV infection was limited to hrHPV 16, 18, 31 & 33 subtypes. Conclusions: Infection by non HPV 16/18 is fairly common. A higher than expected incidence of rare subtype (20% hrHPV31) and multi-viral hrHPV (16%) were detected. This finding stresses the importance of this pilot study as currently only quadravalent vaccine is offered to control the HPV infection in the UAE population.
Diagnostic Pathology
Papillomaviridae
Dive into the research topics of 'Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: A polymerase chain reaction-based pilot study'. Together they form a unique fingerprint.
Squamous Intraepithelial Lesions Medicine & Life Sciences 100%
United Arab Emirates Medicine & Life Sciences 46%
Polymerase Chain Reaction Medicine & Life Sciences 45%
Human papillomavirus 16 Medicine & Life Sciences 38%
Infections Medicine & Life Sciences 36%
Adenocarcinoma in Situ Medicine & Life Sciences 15%
Albawardi, A., Quddus, M. R., Al Awar, S., & Almarzooqi, S. (2018). Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: A polymerase chain reaction-based pilot study. Diagnostic Pathology, 13(1), [42]. https://doi.org/10.1186/s13000-018-0716-x
Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country : A polymerase chain reaction-based pilot study. / Albawardi, Alia; Quddus, M. Ruhul; Al Awar, Shamsa et al.
In: Diagnostic Pathology, Vol. 13, No. 1, 42, 26.06.2018.
Albawardi, A, Quddus, MR, Al Awar, S & Almarzooqi, S 2018, 'Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: A polymerase chain reaction-based pilot study', Diagnostic Pathology, vol. 13, no. 1, 42. https://doi.org/10.1186/s13000-018-0716-x
Albawardi A, Quddus MR, Al Awar S, Almarzooqi S. Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: A polymerase chain reaction-based pilot study. Diagnostic Pathology. 2018 Jun 26;13(1):42. doi: 10.1186/s13000-018-0716-x
Albawardi, Alia ; Quddus, M. Ruhul ; Al Awar, Shamsa et al. / Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country : A polymerase chain reaction-based pilot study. In: Diagnostic Pathology. 2018 ; Vol. 13, No. 1.
@article{c961afd8193f42048980ab10fa14453a,
title = "Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country: A polymerase chain reaction-based pilot study",
abstract = "Background: The incidence of abnormal cervical smears in the United Arab Emirates (UAE) is 3.6%. Data regarding specific high-risk HPV (hrHPV) genotypes are insufficient. Identification of hrHPV subtypes is essential to allow formulating effective vaccination strategies. Methods: A total of 75 archival cervical cone biopsies with HSIL or higher lesions (2012-2016) were retrieved from a tertiary hospital, including HSIL (n = 70), adenocarcinoma in-situ (n = 1) and squamous cell carcinoma (n = 4). Five tissue sections (10-μ-thick each) were cut and DNA extracted using the QIAamp DNA FFPE Tissue Kit. GenomeMeTM's GeneNavTM HPV One qPCR Kit was used for specific detection of HPV 16 and 18; and non-16/18 samples were typed by GenomeMeTM's GeneNavTM HPV Genotyping qPCR Kit. Results: Median age was 34 years (range 19-58) with 70% UAE Nationals. hrHPV detected were 16, 18, 31, 33, 35, 39, 45, 51, 52, 58, 59, 66 & 68. hrHPV testing was negative in 12% of cases. Most common types were HPV 16 (49%), HPV 31 (20%) and HPV 18 (6.6%). hrHPV 16 and/or 18 represented 56% and rare subtypes 32%. Co-infection was present in 16%. Eight cases had two-viral subtype infections and 4 cases had 3 subtype infections. Multi-viral HPV infection was limited to hrHPV 16, 18, 31 & 33 subtypes. Conclusions: Infection by non HPV 16/18 is fairly common. A higher than expected incidence of rare subtype (20% hrHPV31) and multi-viral hrHPV (16%) were detected. This finding stresses the importance of this pilot study as currently only quadravalent vaccine is offered to control the HPV infection in the UAE population.",
keywords = "Cervical cancer, HPV, Papillomaviridae, UAE",
author = "Alia Albawardi and Quddus, {M. Ruhul} and {Al Awar}, Shamsa and Saeeda Almarzooqi",
note = "Publisher Copyright: {\textcopyright} 2018 The Author(s).",
journal = "Diagnostic Pathology",
T1 - Frequency of rare and multi viral high-risk HPV types infection in cervical high grade squamous intraepithelial lesions in a non-native dominant middle eastern country
T2 - A polymerase chain reaction-based pilot study
AU - Albawardi, Alia
AU - Quddus, M. Ruhul
AU - Al Awar, Shamsa
AU - Almarzooqi, Saeeda
N1 - Publisher Copyright: © 2018 The Author(s).
N2 - Background: The incidence of abnormal cervical smears in the United Arab Emirates (UAE) is 3.6%. Data regarding specific high-risk HPV (hrHPV) genotypes are insufficient. Identification of hrHPV subtypes is essential to allow formulating effective vaccination strategies. Methods: A total of 75 archival cervical cone biopsies with HSIL or higher lesions (2012-2016) were retrieved from a tertiary hospital, including HSIL (n = 70), adenocarcinoma in-situ (n = 1) and squamous cell carcinoma (n = 4). Five tissue sections (10-μ-thick each) were cut and DNA extracted using the QIAamp DNA FFPE Tissue Kit. GenomeMeTM's GeneNavTM HPV One qPCR Kit was used for specific detection of HPV 16 and 18; and non-16/18 samples were typed by GenomeMeTM's GeneNavTM HPV Genotyping qPCR Kit. Results: Median age was 34 years (range 19-58) with 70% UAE Nationals. hrHPV detected were 16, 18, 31, 33, 35, 39, 45, 51, 52, 58, 59, 66 & 68. hrHPV testing was negative in 12% of cases. Most common types were HPV 16 (49%), HPV 31 (20%) and HPV 18 (6.6%). hrHPV 16 and/or 18 represented 56% and rare subtypes 32%. Co-infection was present in 16%. Eight cases had two-viral subtype infections and 4 cases had 3 subtype infections. Multi-viral HPV infection was limited to hrHPV 16, 18, 31 & 33 subtypes. Conclusions: Infection by non HPV 16/18 is fairly common. A higher than expected incidence of rare subtype (20% hrHPV31) and multi-viral hrHPV (16%) were detected. This finding stresses the importance of this pilot study as currently only quadravalent vaccine is offered to control the HPV infection in the UAE population.
AB - Background: The incidence of abnormal cervical smears in the United Arab Emirates (UAE) is 3.6%. Data regarding specific high-risk HPV (hrHPV) genotypes are insufficient. Identification of hrHPV subtypes is essential to allow formulating effective vaccination strategies. Methods: A total of 75 archival cervical cone biopsies with HSIL or higher lesions (2012-2016) were retrieved from a tertiary hospital, including HSIL (n = 70), adenocarcinoma in-situ (n = 1) and squamous cell carcinoma (n = 4). Five tissue sections (10-μ-thick each) were cut and DNA extracted using the QIAamp DNA FFPE Tissue Kit. GenomeMeTM's GeneNavTM HPV One qPCR Kit was used for specific detection of HPV 16 and 18; and non-16/18 samples were typed by GenomeMeTM's GeneNavTM HPV Genotyping qPCR Kit. Results: Median age was 34 years (range 19-58) with 70% UAE Nationals. hrHPV detected were 16, 18, 31, 33, 35, 39, 45, 51, 52, 58, 59, 66 & 68. hrHPV testing was negative in 12% of cases. Most common types were HPV 16 (49%), HPV 31 (20%) and HPV 18 (6.6%). hrHPV 16 and/or 18 represented 56% and rare subtypes 32%. Co-infection was present in 16%. Eight cases had two-viral subtype infections and 4 cases had 3 subtype infections. Multi-viral HPV infection was limited to hrHPV 16, 18, 31 & 33 subtypes. Conclusions: Infection by non HPV 16/18 is fairly common. A higher than expected incidence of rare subtype (20% hrHPV31) and multi-viral hrHPV (16%) were detected. This finding stresses the importance of this pilot study as currently only quadravalent vaccine is offered to control the HPV infection in the UAE population.
KW - Cervical cancer
KW - HPV
KW - Papillomaviridae
KW - UAE
JO - Diagnostic Pathology
JF - Diagnostic Pathology


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Use them poolside, outdoors, at casual dinners, large gatherings, or anywhere else you don't want to deal with the hassles of real glass. Choose from a sleeve of 12 or a case of 120.


This book sounds so fresh! I mean, totally original and super promising. I can't wait to read this book, and I really hope that it'll live up to my imagination (and my imagination is EPIC!).
I don't even have to explain this pick to you anymore… because it has been on probably every Top Ten Tuesday list of mine. I pre-ordered quite some time ago and I can't wait for it to be February 25th.
I don't really think I have to explain this one either… Lots of people probably picked it for todays Top Ten Tuesday, so I'm leaving out my reason and am just going to tell you that I desperately want to read it!
Yeah, this one doesn't have a cover yet *sad face* though I have a feeling its going to be a very pretty cover! I think this book sounds so very promising and I can't wait to see the cover and for it to release!
What 2014 Debuts are you Dying to Read?
YES to The Murder Complex and Side Effects May Vary, they are on my list too and I'm so excited for them. I actually have a lot of debuts I'm waiting on this year, my list has 16 debuts. Oops. But somehow I still managed to forget Faking Normal. I cannot believe myself! I'm really excited for that one too!
I actually hadn't heard of Summer on the Short bus before (how did this happen?!) so I must go check this out on Goodreads. How awesome that she's a fellow Dutchie!
16 debuts! I could've borrowed some of yours then, lmao. Cause I only have 7. Ah well..
*wags a finger* you forgot Faking Normal, that's bad! Very bad!
There are so many books on this list that I want to read. . . Side Effects May Vary, Faking Normal, The Murder Complex, Far From You, and No One Else Can Have You. They all sound amazing and just look at those covers! I especially love the one for Far From You. . . It's just so shiny. Great list!
The new design is adorable :D! Side effects may vary sounds like a very good and touching story. I can't wait for The murder complex and hope it will be as action-paced and scary as the blurb promises. So excited for Snow like ashes!
I normally stray away from books like Faking Normal but it just sounds so good!
It does sound good! and I just know it is going to be good!
Your new design is GORGEOUS. Seriously, I love it!
No One Else Can Have You and The Murder Complex sound great!
Great list! I'm going to check out some of the other books on your list. I've got Far From You and Side Effects May Vary on mine this week.
Oh, I love it that you put the dates with it! Such great picks! Faking Normal sounds really good.
Thank you, I was playing around a bit in Photoshop :) Thought it looked cool, so I added the dates. You should really check out Faking Normal! I pre-ordered it and can't wait to finally! read it.
Great list, I've got a few of these on my list too! Side Effects May Vary looks so good, I can't wait for that one. There are so many great books coming out in 2014, I don't know how I'll find the time to read them all. I hope you manage to read all of these :) My TTT.
Yeah I hope I manage to read all of these as well! Though I probably will :) I already pre-ordered some of them, so I'll get to them eventually!
Your new design is beautiful, Iris! It's so delicate. Steph is amazing, isn't she? She helped me code my design, and she did such a great job!
I'm glad you like it! (I do too! haha) Yeah Steph is amazing! She immediately got what I wanted to go for and she truly did a brilliant job!
Aw, I'm sorry you didn't like it more… I hope it'll live up to my expectations! And if not, well, there's tons of other great books around!
You deserve to be mentioned! I'm telling everybody that you made the design (more like gushing about the awesome job you did, haha).
Thanks again Steph! <3 You've been a great help and I'm really grateful!


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In the late 1850s, when Rossini was composing only for his own private pleasure, he wrote a little elegy for Double Bass and Piano that he entitled "Une Larme" ("a tear"). Its theme also served as the basis for a larger-scale set of variations for Cello and Piano. The importance that Rossini ascribed to this short piece for Double Bass is demonstrated not least by the fact that he made a richly ornamented dedication copy of it in 1858. This hitherto little-known source is in Russia and has now been consulted for the first-ever time for a critical Urtext edition. As in Henle's other Urtext editions for this instrument, the Double Bass specialist Tobias Glöckler has prepared a version in solo tuning and orchestral tuning and added fingerings and bowings to the solo part.


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Jail or a power-step up for Black youth?
By Thomas L Blair ©2010
Black youth-savers have fired the first broadside in their fightback against crime and the rising head count of youth in prison and gangs, according to participants in the State of Black Britain conference in London.
After decades of drift, they are targeting under-performing teenagers, street hustlers and the toughest hooligans with a new message: "Salvation is nigh. Aspire and you'll get through the agony, somehow".
But who are the Black youth-savers and have they found the right initiatives for a fateful choice: Inclusion or Incarceration of Black youth?
The preachers
"Street Pastors are the answer to Black crime and disorder," said Rev. Les Isaacs, of a leading voluntary group. Singing from the same hymn sheet are influential Christians – the Anglican bishop of York, Dr John Sentamu, and Baptist leader, Rev David Shosanya, organiser of the SOBB 17 October conference.
A phalanx of Christians supports Rev Shosanya's SOBB initiatives. Keep the Faith magazine editor, Shirley McGreal, is their influential media voice. Andrea Minichiello Williams and the crusading Christian Legal Centre add their expert support.
Crime-busters
Sympathetic police officers and prominent achievers are another youth-saving force. "Tough on crime, tough on the causes of crime" is a repeated slogan. They "aim to halt rising Black on Black crime, drugs, gang wars and anti-social behaviour".
Raising aspirations is on the top of Officer Leroy Logan's action agenda at REALLITY (Raising Everyone's Awareness of Lives Lost in the Youth). The Metropolitan Police superintendent and founding member of the Black Police Association wants to "see lives restored and regenerated not alienated and or destroyed". He offers an antidote to youth crime that leads to streets of peace and safety.
Educators encourage confidence
Successful professionals said increased education and training will bring positive change in the state of Black British youth. "There is no better rung on the ladder of advancement than schooling from the primary to the higher degrees level", said Allan Nigel Smith, Head of Global Risk Strategy, HSBC Bank.
Methodist Black preacher Dr Anthony Reddie, an expert on faith issues for the international journal Black Theology, is in accord. Local magistrate Triumph Ayop Isegun, JP, aims to empower lone parents of susceptible, troubled youth.
Professional youth workers are expanding ways for ex-offenders to serve their communities. Jeremy Whittle of Resettlement UK is determined to steer Black youth away from crime, out of jail and back into productive life. Jeremy Crook's Black Training and Enterprise Group (BTEG) helps young people into jobs, business, and training.
Lawmakers, artists promote role models
Youth-savers in government and the arts are making themselves heard. Attorney General Baroness Patricia Scotland and writer-actor Kwame Kwei-Armah introduced "National Role Models — to "Be an inspiration and Make a difference" — to an audience of 300 in London in December 2009. Moreover, there are no limits to creative advocacy.
Innovators in business are choosing to make a difference. They argue that self-employment and ownership is the way out of poverty and insecurity. "Using their own ideas, youth could start a future in business," is the mantra of Levi Roots. The dreadlocked musician's Reggae Reggae sauce "put music on the food shelves" of British supermarkets.
The supremely confident Rev David Shosanya, concluded, "In the midst of social and economic turmoil, youth must become political literates and learn the rhetoric of the media and public square, and study every issue and use their vote wisely".
Take a Power-Step Up
But Black youth-savers may have underestimated the challenges they face. Looking at the larger picture suggests they have more to do to secure inclusion over incarceration of Black youth.
The inclusion bells will ring when young people's creativity and income-production revitalise Black communities. The Hallelujah Day will be a-dawning when youth programme their futures with sustainable aspirations, vibrant organisations and life-affirming moral practices.
The national implications are clear said youth champion Lord Victor Olufemi Adebowale, first "People's peer" and social care charity leader: " Black youth are a potent symbol of a stronger civil society".
*This is the fourth instalment in the Black History Month 2009 series on Unshackling the Afro-British Mind published here by the author. It is hailed as essential reading for anyone who wants to chart the present failures and future prospects in the State of Black Britain. Thomas L Blair is a Black scholar and independent commentator on Black urban affairs at http://www.Chronicleworld.org. Details of his book THE AUDACITY OF CYBERSPACE -The struggle for Internet power can be viewed at http://bit.ly/m-ybooksblair and is highly recommended by the citizens' journal http://www.The-Latest.com.
Posted in Black history, Black London-Britain-Europe info-monographsTagged Baroness Patricia Scotland, Black Police Association, John Sentamu Bishop of York, Keep the faith magazine, Kwame Kwei-Armah, Levi Roots, Lord Victor Adebowale, REALLITY, Rev David Shosanya, Rev Les Isaacs, State of Black Britain, street pastorsBy chronicleworld.wordpress.comLeave a comment
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redpajama_set_name: RedPajamaCommonCrawl


The only way to really come out on top truly is to drop the fear and start living – that's what Charlene Mercieca can tell you. The 32-year-old is just coming out of a six-month stint with breast cancer, which cost her hair and breasts, but not her love of life.
"It only first hit me when I went to my first chemo treatment. I started crying. It wasn't an easy ride, and it's not like I was jolly-jolly throughout the whole thing," she told me in the sitting room of her quaint little shop in Sliema.
"But even people who are cured of cancer feel scared because you never know if it could come back. But then again we don't have any guarantee that we won't die the minute we walk out the door," she said, being her brave and positive self.
Indeed, this is the attitude she kept throughout her entire experience with the dreaded disease.
So, I asked her what her reaction was when she first found out she had cancer.
When the results came in while she was abroad, Charlene was told to come into the doctor's office straight away.
"At that point, I got a little nervous because I was already putting two and two together. When I eventually went to see the doctor he told me I was right and that I had cancer," she said.
Doctors decided the best option was to turn Charlene's treatment on its head, starting first with chemotherapy over a period of six months and then performing surgery, for fear of the cancer spreading if they operated before.
Charlene, who is a qualified beautician, product designer, herbalist, make up artist, spa consultant, as well as an avid researcher of natural remedies, had always put her faith in nature, but in this case she had to find a balance.
"I started chemo two weeks after my diagnosis. But I attribute my recovery to a combination of lifestyle change as well as the treatment itself.
"Most people like to go to extremes, they either want something completely natural or they want something backed by scientific data. In my case, I like to have both, and since my cancer was very aggressive I couldn't wait for nature to take its course.
Cancer can be a gruelling experience physically, but it can be destructive for one's mental wellbeing.
Charlene made it clear that cancer would not break her spirit.
But even then, how does one manage to stay positive when faced with such hardship and uncertainty?
On Facebook, Charlene described her experience and the psychological journey she went through. It was much easier to be open about her ordeal, and she also found relief in putting her feelings down on paper. But the aftermath of her cancer treatment has also left its battle scar.
"I was not afraid of having my chest removed. It was scarier to wonder if I was going to survive the surgery or not… But I wasn't really sad to see my breasts go. I was more anxious about going under the knife, and if, even after the operation, the tumour would spread.
Charlene still chose to undergo reconstructive surgery to combine the two operations. During the mastectomy, doctors inserted two expanders which are gradually filling with saline to expand her skin. There is a next phase of the reconstructive surgery. But Charlene is not in any rush to do it.
Ultimately, Charlene says that the key is taking control of the situation, and that includes one's health.


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Home » News » Movies » Katrina Kaif, Akshay Kumar Get to Singing in the Rain for Tip Tip Barsa Paani Remake in Sooryavanshi
Katrina Kaif, Akshay Kumar Get to Singing in the Rain for Tip Tip Barsa Paani Remake in Sooryavanshi
Sooryavanshi is reuniting Katrina and Akshay nine years after their last film together Tees Maar Khan, and there is a lot of fan expectation regarding the recreation of this sensuous song from Mohra.
Last Updated:June 25, 2019, 16:53 IST
Akshay Kumar and Katrina Kaif are seeking to recreate the magic of the Mohra song Tip Tip Barsa Paani in Sooryavanshi. While shooting for the song, which originally starred Akshay with Raveena Tandon, Katrina shared a behing-the-scenes photo from the sets. The black and white photo shows the actors with towels wrapped around their heads, sharing a laugh.
Sooryavanshi is bringing together Katrina and Akshay nine years after their last film Tees Maar Khan, and there is a lot of fan expectation regarding the recreation of this sensuous song. Katrina and Akshay had earlier paid a tribute to Tip Tip Barsa Paani in their film De Dana Dan, with the song Gale Lag Ja, in which the actress was seen wearing a yellow saree.
The latest photo she's shared from the sets of Sooryavanshi doesn't show Katrina wearing a saree. She is seen in a white crop top. Whether that is the real costume for the song as well, that remains to be seen. Take a look at the photo:
Singing in the rain ☔ #sooryavanshi @akshaykumar @itsrohitshetty @farahkhankunder
A post shared by Katrina Kaif (@katrinakaif) on Jun 25, 2019 at 2:04am PDT
Akshay and Katrina were supposed to kick off the Hyderabad schedule of the Rohit Shetty directorial with a romantic song. A source close to the film had said, "The reprised version is composed by Tanishq Bagchi while Farah Khan has come on board to choreograph Akshay and Katrina's moves. It is a sensuous romantic song like the original, and Farah has already discussed her vision of the track with Rohit."
Read: Akshay Kumar to Recreate the Magic of Tip Tip Barsa Paani with Katrina Kaif in Sooryavanshi
Sooryavanshi is produced by Shetty and Karan Johar. It is reportedly the costliest cop film ever made in the history of Indian cinema. Akshay will be seen playing the role of DCP Veer Sooryavanshi, Chief of the Anti-Terrorism Squad, whereas Kat will play the character of his on-screen wife.
Recently, Akshay had tweeted that he would have been disappointed if any other actor would have recreated the song. He said, "I would've definitely been disappointed if any other actor would've recreated Tip Tip Barsa Paani,a song which has been synonymous with me & my career."
I would've definitely been disappointed if any other actor would've recreated Tip Tip Barsa Paani,a song which has been synonymous with me & my career & I can't thank Ratan Jain ji enough. At times like these you realize,we may have come a long way but we also go back a long way pic.twitter.com/UtH5iDS0i9— Akshay Kumar (@akshaykumar) June 20, 2019
akshay katrina sooryavanshi
Mohra
Tees Maar Khan
Tip Tip Barsa Paani
Tip Tip Barsa Paani Remake
first published:June 25, 2019, 16:53 IST


"Lifestyle Medicine" is one of the newest defined and growing fields in healthcare today. Come hear the "inside story" of its development, struggles, and triumphs in paving the way for transformation to a better, brighter future of truly evidence-based effective and affordable healthcare for tomorrow; as well as what it looks like in its development in the Salem area today with multiple healthcare professionals.
This conference will focus on the need for action for mothers and babies impacted by the opioid and other drug epidemic. An emphasis will be placed on medical concerns around pre-natal care, issues during labor and delivery, as well as post-delivery necessities to build resources to ease the life consequences for these children.
Presentations, facilitated discussions, skill building workshops and networking to build understanding and share resources.
Sponsored by Marion County Health & Human Services, Bridgeway and WVP Health Authority.
JOIN US FOR THE BEST NETWORKING EVENT OF THE YEAR!
We are committed to fostering relationships, and look forward to this opportunity to bring you together with your colleagues in celebration of the new medical providers in our local community!
Hosted by the Marion-Polk County Medical Society, this exclusive event features delicious appetizers, wine pairings and live music.
All MPCMS Members are welcome to attend with a guest, as are non-members (MDs, DOs, DPMs, NPs or PAs) who are new to the area in the last three years.


The Library Board sets policy for our local library. The board coordinates with the Friends of the Library and coordinates county and city policies. The board recommends to Brazoria County and Lake Jackson City Council.
If you would like to contact the Library Board, please contact the City Secretary's Office.


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Hobart & Surrounds Highlights
Home » Explore » Day Trips » Richmond Tour
Richmond Tour
Bonorong Wildlife Park
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Coal Valley Vineyard is a 5 hectare winery in the Coal River Valley, producing award winning wines with a passion and focus on Pinot Noir. ...Read More
Old Hobart Town
Old Hobart Town is Australia's only and Tasmania's original historical model village which accurately replicates in miniature the life and history of Hobart in 1820....Read More
Richmond Bridge
The sandstone arches of Richmond Bridge have spanned Tasmania's Coal River since 1825. Built by convict labour, it is Australia's oldest surviving large stone arch bridge....Read More
Tasmanian Golf Club
Tasmania Golf Club is bordered by water on three sides and situated on the picturesque Barilla Bluff, only 15 minutes east of the Hobart CBD....Read More
Zoo Doo Wildlife Park
Zoodoo Zoo is a hands-on safari and native animal park. Visitors are able to feed lions, meet reptiles, and see Tasmanian devils and other native animals up close every day during keeper presentations...Read More
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Research group seeks to promote crystals as drug delivery, development tools
by Michael Gibney |
The formation of crystals, magnified--Courtesy of U. of Lincoln
Materials science is a crucial facet of the drug delivery realm, and researchers in the U.K. and Ireland are rallying to bring attention to the importance of crystallization in the future of drug development and delivery.
Researchers Simon Lawrence of the University College Cork and Nicholas Blagden at the University of Lincoln have formed the Crystallize research network to bring together scientists around the world to increase the understanding of crystallization and the part it is likely to play in the biotech industry, from development and engineering to manufacturing. And drug delivery is a big part of that future, as crystals can help transport small molecules as well as large biologics to help create viable doses from poorly soluble ingredients, according to a report from the University of Lincoln.
The group's aim is to bring about both academic and industrial growth in the area of crystal design and application, particularly in the pharmaceutical realm. They will meet for the first time this month in Marseille, France, to discuss the very nature of crystallization and how molecules form crystals. Harnessing this natural mechanism can lead to important advances in drug delivery down the road.
"The big problem is that we have still got a lot to learn about how crystals actually grow as it's not clear how they change from a liquid to a solid state," Blagden said in a statement. "This is called 'nucleation' and is the first step in crystallisation, determining if a crystal can form from a liquid state. A bigger effort has now begun to understand crystallisation and how it impacts on everything from chemicals to pharmaceuticals. We need to understand this process so we can deal with the bigger problems. It's about sharing advice and experience."
In his own research, Blagden and his team are growing nanocrystals on small plastic chips, looking to produce large volumes of the material for industrial use. Growing these together as a cocrystal with materials such as sugars or vitamins could offer better delivery and more viable doses.
- here's the U. of Lincoln report
Special Report: Nanocrystals- When nanotech meets biotech
U.K. adopts UCB and kitchenware maker OXO's Cimzia self-injection pen
A self-injection pen prefilled with Brussels-based UCB's Cimzia (certolizumab pegol) has been made available this week in the U.K. after a positive opinion…
by Michael Gibney Oct 25, 2016 9:42am
Everstone buys majority stake in Indian drug delivery firm Rubicon
Everstone, a private equity firm specializing in India and Southeast Asia, has finally decided to shell out Rs 220 crore ($33 million) to obtain a 70% stake--a…
by Angus Liu Oct 24, 2016 4:35pm
Michael Gibney


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Home News I couldn't farm without it!
I couldn't farm without it!
For some it's duct tape. For others, their Leatherman. Or baler twine. Or their smartphone.
So we want to know: What is it that you can't farm without?
What's the tool, the piece of equipment, the software, the person, the thing, that is indispensable on your farm? You use it every day. Or at least every week. Or it's the thing that makes your farm life so much easier, or more profitable.
Email your responses to editorial@farmanddairy.com, or mail them to P.O. Box 38, Salem, OH 44460. If you want to include an explanation, that would be great. If not, we'll take your simple answer. And if you want to include a picture or two, that would be great! Please include your full name, address and phone number/email. Those won't be published, but if we want to hear more about your answer, we'd like to contact you.
Send us your wisdom by Wednesday, Sept. 7. We'll compile the answers and share them in our special Farm Science Review issue, Sept. 15.
So tell us: What can't you farm without?


text:
Q: VS extension does not pop up sign in dialog I am developing a VS 2015 extension that should connect to VSTS (VisualStudio.com) and pull out backlog items.
The code below works in a console app but not in VSIX project. I call it from a menu item in Team menu (IDM_MENU_TEAM_FOUNDATION_CLIENT).
using Microsoft.VisualStudio.Services.Client;
using Microsoft.TeamFoundation.WorkItemTracking.WebApi;
using Microsoft.TeamFoundation.WorkItemTracking.WebApi.Models;
...
public WorkItem GetItems(int itemId) {
    var myCredentials = new VssClientCredentials();
    var vstsConnection = new VssConnection(new Uri(@"https://myaccount.visualstudio.com/"), myCredentials);
    var vstsClient = vstsConnection.GetClient<WorkItemTrackingHttpClient>();
    var workItem = vstsClient.GetWorkItemAsync(itemId).Result;

    return workItem;
}

I believe the issue is that the console app can call the sign in screen without any issues. The VS 2015 Experimental Instance, where the VSIX code runs, does not. My research so far does not point to anything useful.
Is there a proper way to connect to VSTS from Visual Studio Extension? What am I missing?

A: Modify your code like this:
private void GetWorkItem(object sender, EventArgs e)
        {
            System.Threading.Tasks.Task.Factory.StartNew(() =>
             {
                 var w = GetItems(123);
                 MessageBox.Show(w.Url);
             });

        }

 public WorkItem GetItems(int itemId)
        {
            var myCredentials = new VssClientCredentials();
            var vstsConnection = new VssConnection(new Uri(@"https://xxx.visualstudio.com/"), myCredentials);
            var vstsClient = vstsConnection.GetClient<WorkItemTrackingHttpClient>();
            var workItem =  vstsClient.GetWorkItemAsync(itemId).Result;

            return workItem;
        }

redpajama_set_name: RedPajamaStackExchange


Shayne can't be fixed without a full update. Reyna's homing doesn't work as intended? That's news to me, can you elaborate a little on that?
Although the format used was not appropriate according to forum rules, it was still the funniest post I've ever read on these forums.
I mean, can you deny they look a little man-ish?
It actually made the picture funnier for me, so extra updoot to the artist!
Yawn. No Lootpocalypse, no patch to fix Kelvin's lore.
Are there any plans for balance changes in the near future for characters and gear(Bolos)?
Finally, I could be alone in this thought but I would much prefer new maps as content opposed to these events like Rockets and Yankerz.
Also, petition to change Boldurs level 20 title to BoldurBorn.
new maps would be nice. I'm not a big fan of early mellka(or this new one) so a rework would be nice to see.
this was posted on june 8th so take it for what you will, after all it took them over a year to get galilea to where she was.
Once u master melka, you become rly hard to kill.
My isseu with her is how easy she can become broken/op, with all the dmg boost she got she is usually btw the highest dmg dealers, minions and players killed.
If they buff her hp there are a chances for a) players still using health gear being more tanky and harder to kill or b )they use new loadouts becoming stronger.
Melka is a hero with high skill required to be good in more aspects than any hero, mechanically with high sensevility so you can move easier and dodge using airstall/claw lunge, good map notion as you need to look to the oposite direction to get over a ledge, awareness to know when to leave, etc.
Im glad they are taking their time to change her, as i expect a good helix rework. Currently she is 1 path helix with small variations.
So I gave up on waiting for new actual skins and spent most of my plat on Magnus Packs.
@vagrantsun and @HandsomeCam Your main (Toby) was the only Magnus Skin I got…I guess I'm a Toby main now too, welcome me with open flippers.
At least the skin looks very spiffy. Reminds me of Mad Max.
Going to Valhalla Shiny and Chrome…!!!
Commenting on your comment about the comment in question is a mine field which I shall not be entering.
I'm sorry man. I know Lobbyborn can be tough. Here's a repost of Shatner singtalking Rocket Man to keep you company.
[pc] We did a lore lobby and there were some ten mans going on last night after i got off.
Discord fam isnt struggling. Sorry to everyone who doesnt like discord.
More dailies? more platinum from dailies? It's not a big increase I'm asking for just something, I really don't care about these gimmick type of matches, they just spread the player base out even more.
they increased all taunt prices. all skins that weren't 700 are now 700 some went up to 1k some went down to 700. and for whatever reason shanes clown skin went to 1,400 so i have doubts that they would want platinum to be more obtainable.
Two. Down Range and something else.
… they are all 350? they used to be 230 if i remember right.


Welcome to the online home of Smart Plumbing Solutions.
Through this website, we hope to bring you everything you'd ever want to know about our local plumbing services, and perhaps a little more too.
Smart Plumbing Solutions is a local plumbing business owned by Tim Smart, a Chalfont St Giles based plumber who covers the Buckinghamshire and Hertfordshire areas.
We always pride ourselves in offering you a thorough plumbing service from start to completion including our quality after sales service. Whether it's a repair, replacement or a complete refurbishment you're looking for, Smart Plumbing is the Solution.
We are a professionally run local plumbing business, ideally located in the heart of Chalfont St Giles with excellent access to Chalfont St Peter, Gerrards Cross, Chorleywood, Beaconsfield, Seer Green, Amersham and the surrounding Buckinghamshire and Hertfordshire area.
This map shows the broad area we cover. However, please contact us to ascertain if we are able to cover your area.
See the full list of the areas we cover.
Smart Plumbing Solutions is a local plumbing business owned by Tim Smart.


We propose a terahertz broadband absorber composed by silicon strips with continuous graphene on top of a metal mirror. The simulation results show that under the combined effect of the Fabry–Perot resonance and the dipole mode oscillation excited in the silicon strip array interacting with graphene, this structure can achieve an ultra-wide absorption band from 0.73 to 1.95 THz with absorbance of 90%. By changing the size of the silicon strips or the Fermi level of graphene, the working band of the absorber can be tuned.


text:
Why our minds can't make sense of COVID-19's enormous death toll
As we reach grim milestones—200,000 dead in the U.S. and one million globally—our new challenge is overcoming the natural tendency to go numb.
Funeral director Omar Rodriguez inventoried bodies, all coronavirus disease (COVID-19) victims bound for cremation, in the main chapel of the Gerard J. Neufeld Funeral Home in Queens, New York, April 26, 2020.
Photograph by Timothy Fadek/Redux
BySarah Elizabeth Richards
When the COVID-19 pandemic started nine months ago, the current reported death tolls were unthinkable. Yet this week, the fatality count has reached 200,000 people in the United States, and global deaths have exceeded one million.
Although health officials say the real toll is likely much higher, due to a percentage of coronavirus deaths not being officially classified, the 200,000 statistic is a heartbreaking milestone. It's a symbolic grim number that's seared into the public's consciousness and marks another alarming level of escalation in the pandemic.
The tally means a U.S. death has happened every 1.5 minutes, on average, since the first official fatality in late February. It's also the equivalent of wiping out a small city—such as Salt Lake City, Utah or Akron, Ohio—or a quarter of Washington, D.C. It means we have lost 1,450 plane loads full of people. (Here's where cases are growing and declining in the U.S.)
"If you think about it like that, assuming there are 138 seats in a classic 737, that would mean eight planes have crashed on U.S. soil every day," says David Kessler, Los Angeles-based grief specialist and author of Finding Meaning: The Sixth Stage of Grief. "Can you even imagine that?"
Although that number is fodder for disturbing mental images, what's unknown is how it will affect people's collective and individual psyches. Is 200,000 deaths an important threshold that kicks us in the gut and creates a new level of urgency and outrage? Or will it lead to numbness and disengagement?
Ultimately, our biology is working against us. Researchers say our brains aren't wired to make sense of big numbers. We're also trying to digest coronavirus death tolls amid a sea of other worries, including economic uncertainty, civil unrest, wildfires and hurricanes, geopolitical strife, election tensions, and unprecedented shifts in how we work, shop, socialize, and educate our children.
"The whole country is depressed," says Elke Weber, a Princeton University cognitive psychologist. "If you're already stressed out, the 200,000 statistic becomes just another thing."
But experts say there are ways to absorb and cope with the news without feeling overwhelmed or apathetic.
Arithmetic of compassion
More tragedy doesn't always elicit more empathy; it can counterintuitively bring about apathy. The magnitude of the death toll can cause some people to become less compassionate, says Paul Slovic, a psychologist at the University of Oregon, due to a phenomenon he calls "psychic numbing."
In a 2014 study that looked at charitable giving, Slovic found that people's concern for those in distress didn't increase as the number of needy cases did. "Our feelings are very strong for one person in danger, but they don't scale up very well," he says. "If there are two people, you don't feel twice as bad. Your attention gets divided, and you don't have as strong an emotional connection."
Slovic suggests our brains evolved this way as a coping mechanism. Millions of years ago, humans weren't even aware of distant people's plagues, conflicts, or disasters, so we naturally focused on protecting ourselves, our families, and our small communities.
In addition, the long duration of the pandemic, combined with the absence of a clear end, can dull people's sense of shock, other experts say. Simply put, some brains have gotten used to hearing about COVID-19 deaths to the point where higher numbers no longer register emotionally.
If you think about people living in a war zone, the kind of thing that was once appalling
becomes normal.
ByElke WeberPrinceton University
"The human species is really adaptive," says Weber, who studies how people make decisions when facing risks and uncertainty. "If you think about people living in a war zone, the kind of thing that was once appalling becomes normal. Our brain neurons fire when something changes, but they stop after a while. If you're in a room with a bad smell, you eventually stop noticing it."
This feeling of being in the middle of a crisis has prevented us from mourning and creating the types of memorials that help us connect with victims, such as the inscribed names of loved ones that people can visit and touch the September 11 Memorial in New York City, or the Vietnam Veterans Memorial in Washington, D.C. Those rituals usually are created after an event has occurred or when a crisis has ended, says Yu-Ru Lin, an associate professor at the School of Computing and Information at the University of Pittsburgh in Pennsylvania.
In her research, Lin has documented people's emotional reactions on social media to "short-term and shocking" events or natural disasters, such as this study about the 2015 terrorist attacks in Paris. She has found that being able to express a surge of emotions after the defined event helped people cope.
Viral memes that often circulate on social media following certain tragedies can also spark emotional responses that resonate, such as how the horrific image of a Syrian refugee toddler who washed ashore on a Turkish beach in 2015 led to record donations to help victims of Syria's civil war.
Having an actual place to go where the tragedy occurred and perhaps even bring flowers has also been key to processing grief. "When I studied the [2013] Boston Marathon bombing, people had gatherings and ceremonies after the event and would even have an anniversary event to remember these losses," Lin says.
By contrast, the coronavirus is everywhere, and people don't have a way to process their amorphous, long-haul grief. No single iconic photo that conveys the gravity of the pandemic has emerged and prompted mass indignation. Due to restrictions on social gatherings, many family members of victims cannot even attend funerals, let alone visit memorials that haven't been built.
A common stress response to unpleasant thoughts is to deny them or simply shut them out.
There's also the fact that while the death toll is high, most people in the U.S. haven't yet experienced the loss of a loved one, and that makes a big and grave number feel more remote.
"These impacted communities are quite invisible to many people, unless you know of someone in your social network," says Lin. "For others, the loss is more ambiguous," like the interruptions to normal life or not being able to visit people in the hospital.
Another reason some people are tempted to check out emotionally is that humans struggle with tolerating the uncertainty of whether COVID-19 will surge in the winter or whether and when an effective and safe vaccine will become available. A common stress response to unpleasant thoughts is to deny them or simply shut them out.
"It calms us down," says Mardi Horowitz, a psychiatrist at the University of California, San Francisco, who studies grief and trauma.
No excuse for apathy
So how can we make sense of such heavy news?
"When we see this death toll, it makes us feel frightened and sad. The important thing is to tolerate the pain and think reasonably what we can do to help people through it," says Horowitz. He adds that it's important to acknowledge feelings of indignation, hopelessness, and despair—and then move through them. "We have to strive for the middle ground in these extremes. It makes people feel better and restores our collective goals," he says.
The best way to avoid compassion fatigue is to think of individuals with faces, names, and families, says Slovic. "Someone once observed, Statistics are human beings with the tears dried off," he says. Not surprisingly, his research found that people were more likely to donate to needy children when they saw photos and learned more about their circumstances.
People are hitting the wall because we're talking about these deaths in every other way except loss.
ByDavid Kesslerauthor of Finding Meaning: The Sixth Stage of Grief.
The same principle holds true for coronavirus victims. Death tolls become more meaningful when we have a chance to get to know and honor the people who are gone, says Kessler. "People are hitting the wall because we're talking about these deaths in every other way except loss," he says. "It's a political device or a medical crisis or a mask debate. We're not talking about Juan's mother or Susan's brother."
Kessler says a healthy coping mechanism is to use those personal connections to motivate positive change. "Maybe you witness a mask debate and you tell people, I heard that Jane's brother died. Do you see that 200,000 people also died? Maybe you could cover your nose," he says.
Our limited capacity and our desire to avoid uncomfortable feelings shouldn't allow us to disengage, says Kessler. In fact, he argues that numbness can fuel much-needed action. "When I visited the death camps at Auschwitz, I saw the shoes and glasses of the people who died, and it made me numb. But when I left, I said to my numbness, What can I do to prevent this?" says Kessler. "Numbness should not let us off the hook."
Editor's note: This story has been updated to reflect that the U.S. death toll has surpassed 200,000 and that the global tally has reached one million. This story was originally published on September 21.


text:
Mobile industry completes 5G standard by approving standalone 5G spec
Jeremy Horwitz@horwitz	 June 14, 2018 6:37 AM
Working under the auspices of international standards organization 3GPP, the mobile industry today confirmed that it has achieved a critical milestone in the race to bring 5G networks to life: official approval of "5G standalone" specifications. In a collective announcement, 3GPP and dozens of wireless companies are describing the approval as kicking off "the final sprint towards 5G commercialization," which will begin in the United States this year, and elsewhere next year.
Last December, 3GPP approved the earliest 5G "non-standalone" specification, which enabled chip, device, and network makers to develop early 5G products that partially leveraged existing 4G/LTE networks. The newly completed specification enables developers to choose from a standalone 5G standard that doesn't depend upon 4G, or the earlier non-standalone 5G standard with 4G ties.
While the announcement might seem obscure to the average person, completion of the final "Release 15" 5G standard is the product of 34 months of individual and collective engineering accomplishments and is expected to have society-transforming impacts. 3GPP convened the meeting to complete Release 15 in May, bringing together 1,500 experts in Busan, South Korea for the final push.
In a statement commemorating the achievement, 3GPP TSG CT chair Georg Mayer said:
Two years ago, 5G was seen as a vision or even just a hype — with the closing of Rel-15 3GPP has made 5G a reality within a very short time. The outcome is an amazing set of standards that will not only provide higher data rates and bandwidth to end customers but which is open and flexible enough to satisfy the communication needs of different industries.
Wide and deep industrial impacts are expected now that the 5G standard is complete. On the consumer side, ultra-high-definition videos can be shared over cellular connections, and video game consoles, virtual reality headsets, and augmented reality devices are similarly anticipated to benefit from high-bandwidth, low-latency streaming of content from remote servers. Additional applications include advanced factory automation, autonomous vehicles, bringing entire city infrastructures online, and much more.
Over 600 delegates from a wide swath of mobile network companies participated in this week's 3GPP sessions, including representatives from AT&T, Deutsche Telekom/T-Mobile, DISH Network, Intel, Qualcomm Technologies, StarPoint, and Verizon, as well as leading British, Chinese, European, Japanese, and Korean hardware and network companies. Many of the companies have offered individual statements outlining their 5G progress and plans going forward, effectively reaffirming their prior commitments to begin deploying 5G in the near future.
Readers interested in learning more about the 5G New Radio standard can check out a Samsung-developed whitepaper that discusses the completed standard in greater detail.


We really appreciate your interest in Celox. It's a great technology which needs great people like you to put it to work. Celox is available from a network of distributors around the world. To find your distributor please use the attached link to send an enquiry.
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WebObjects 5 projects will require converting with the JavaConverter, whether or not they are already written entirely in Java. This is best run from a Bourne Shell, and is at $NEXT_ROOT/Library/WebObjects/JavaApplications/JavaConverter.woa/JavaConverter.cmd. Run it with the full path of your chosen project and it will create a new project, whose name will be the original name with "Java" appended.
You should then be able to open the new project and browse the source code. The Java Converter has non-trivial tasks to perform, more so if you've come from Objective-C, so you'll want to read through your source code and check it's done a job you're happy with. As an alternative, you could search merely for its comments (labelled JC_WARNING or JC_ERROR) and review each one.
Note that the Makefile will be removed by the conversion process, and for some reason best not asked about, Project Builder will recreate the Makefile only if files are added or removed from the project - and not in the rather more obvious case where you try to build and there is no Makefile. So you'll need to add and remove a dummy class, for example, before your project will build.
EOModels will need converting to the JDBC adaptor. Since JDBC is itself a multiple-database protocol, the JDBC adaptor itself does not have the usual knowledge of external types - but if you give it an appropriate database URL and it can locate the appropriate plugin, it will then know which types are possible, so you can use the external type pulldown list to get them right. The JDBC adaptor and EOF 5 is, of course, a whole new learning curve of little fiddly bits, so expect to have to spend a bit of time experimenting and reading up in order to make all your database types work correctly, especially if it is complex. As the community (and the database vendors) discover more about the environment, this stage is becoming easier and easier.
Once your application is built you can run it, of course. Be aware WebObjects 5 uses some bizarre scripts to launch applications, and these are worse than usual on Windows, where the command line has a maximum length, so your classpath may not fit. My personal opinion (MalcolmCleaton) is that this is an extremely ill-conceived method for launching Java applications, and you'd be best off doing away with it as soon as possible, but that's another discussion.


text:
The sea seen from land
At 13:02 on Sunday 29 October, Gitana 11 and Gitana 12, along with 10 other Orma trimarans, will set sail in the 8th edition of the Route du Rhum. While the twelve skippers will find themselves alone aboard their boats from 12:00 onwards for ten days or so, back on dry land, an entire team will operate a 24-hour vigil to ensure the weather monitoring and to intervene at any moment in support of the solo sailors.
The trimaran preparation phase has required both the time and energy of the skippers and, alongside them, a full technical team has toiled to adapt the multihulls to this transatlantic race and to meet the specific requests of each single-handed sailor. It was a task that took several weeks, not to say several months, in alternation with ocean forays designed to test the platform. Then came the last few days of fine tuning in Saint-Malo under the glare of the media spotlight which can destabilise even the steadiest temperaments. Now the hour of departure approaches and the soloist has to tune into the ocean whilst at the same time responding to the most mundane of questions: it's a mental balancing act that requires singular skill… For single-handed multihull sailing can be likened to a high-speed train hurtling along a rough old track without stopping at any stations, and doing so for ten/twelve days with a single driver who has to watch out for other traffic, operate the points, provide the catering service and maintain the machinery…
Everything ship shape
In the days leading up to the start what is most important is the performance of a final check on the boat's communication, computer and electronic systems. Within the Gitana Team, there is always a boat captain and his assistant among the crew: William Fabulet and Sébastien Thetiot for Gitana 11, Léopold Lucet and Richard Loncle for Gitana 12 take care of any last-minute "tweaks" alongside Richard Bastide, the team's embedded systems specialist (Inmarsat, Iridium, Fleet, image sending, etc.). By this point, the soloists need to have acquired a perfect grasp of the instrumental processes so that they can access them very fast and waste as little time as possible once the starting line has been crossed. For the two Gitanas, the last four days before the start sees a meeting held every morning to analyse the weather information with the skippers Lionel Lemonchois and Thierry Duprey du Vorsent, in the company of Sylvain Mondon from Météo France and the "routers", Mayeul Riffet and Yann Guichard, who track the boats from on land, and also Loick Peyron, who is supervising the Gitana Team's strategy.
The good news to emerge from Saint-Malo over the last few days is that the weather conditions for the start will be very manageable, if a little rough and changeable. Essentially, the breeze should remain gentle and variable for the exit from the Channel and, up until the Azores, the trajectory should be straightforward. The atmosphere around the Vauban Basin is calm with no perilous low-pressure front exiting the Channel, as was the case four years ago and on other Route de Rhums. The forecast also alters the skippers' mental preparation as they prepare for the drink….Yo, ho ho and a bottle of Rum!
Ensuring a smooth start!
For the start, two Gitana Team dinghies will be on the water and three crewmen will board them from the trimaran just ten minutes before the cannon sounds: they will disembark after having raised the sails and carried out the final adjustments to help the skipper. Like the majority of the other technical teams, the Gitana Team has loaded two vans with two dinghies which will leave at 15:00 on Sunday for Perros Guirec so as to organise a possible pit stop should one of the boats require it. The idea here is to be able to reduce to a minimum the detour taken by the boat and the length of any stop. The team can very speedily pick up a spare sail or a piece of rigging, change electronic equipment or a defective automatic pilot, etc…
Once the trimaran exits the Channel, the technical team stays on stand-by for possible intervention abroad, namely at the tip of Spain, in Portugal or in the Azores: Jean, Olivier, William and Léopold thus form a "hit squad" capable of resolving all manner of technical problems.
On land during the race, a weather assistant collects the daily reports and the information from all over the world in order to have a range of sources that's as diverse as possible. The "land routing" team then establishes, in conjunction with the skipper, a general strategy that takes into account the position of the other competitors. "Virtual gateways" are indicated for the skipper to pass through within a given time, or whether it is better to go as fast as possible or simply stick to a precise course.
The solo sailor can call the team at any time of day or night through the intermediary of an allocated contact for all interventions concerning the boat or the weather situation on the water. In fact, the majority of phone calls are made in the sea-land direction so as not to disturb the skipper who would have to disrupt his routine in order to answer a call.
After that, it's a case of steaming into the home straight and getting ready for the finish in Guadeloupe…
Gitana Team shore crew :
*Loïck Peyron, General director
*Jean Le Huérou-Kérisel, technical director
*Cyril Dardashti
*Olivier Wroczinski
*William Fabulet et Sébastien Thetiot, Gitana 11
*Léopold Lucet et Richard Loncle, Gitana 12
*Laurent Rivals, logistic
*Jean-Pierre Trottet, Daniel Le Digabel, Marie Dixneuf
*Richard Bastide
*Benoît Piquemal
*Sylvain Mondon, météo
*Yann Guichard
*Mayeul Riffet


text:
Doha selected as the Capital of the Islamic Youth for 2019
- March 12, 2019 March 12, 2019
The State of Qatar has received the key of 'Doha — OIC Youth Capital 2019' in recognition of Qatar's efforts to support and empower young Muslims.
This came at the closing ceremony of 'Al Quds Ash Sharif — OIC Youth Capital 2018', which was held in Ankara in the presence of Salem bin Mubarak Al Shafi, Qatar's Ambassador to Turkey; Abdurrahman Mohamed Al Hajri, Advisor to the Minister of Culture and Sports; Ministers of Youth and Sports of Turkey and Palestine, and the president of Islamic Cooperation Youth Forum (ICYF).
On the occasion, Salem bin Mubarak Al Shafi delivered a speech in which he conveyed the greetings of Minister of Culture and Sports H E Salah bin Ghanem Al Ali and his wishes of the success of the ceremony.
The Ambassador expressed his thanks to State of Palestine. "We thank Palestine for its efforts in supporting the work of the Islamic youth, and we in Qatar have been keen to support the efforts of our brothers during this year."
He also expressed his deep appreciation and gratitude for Turkey for hosting the closing ceremony of 'Al Quds Ash Sharif – OIC Youth Capital 2018'.
He also appreciated the Organisation of Islamic Cooperation (OIC) and the Islamic Youth Conference for Dialogue and Cooperation for all the efforts made over the past years in supporting joint Islamic youth work in exchange of knowledge and experience.
Salem bin Mubarak Al Shafi stressed the aspiration of the State of Qatar to strengthen cooperation among nations. "We promise you a year of outstanding youth activities and programs in accordance with the directives of Amir H H Sheikh Tamim bin Hamad Al Thani to take care of young people in all sectors."
"We welcome everyone to their second country, Qatar, an oasis of goodness and now 'Doha – OIC Youth Capital 2019'.
The event was followed a press conference attended by Abdurrahman Mohamed Al Hajri, Advisor to the Minister of Culture and Sport and Turkish and Palestinian ministers.
Al Hajri stressed the keenness of the Ministry of Culture and Sports to provide a range of activities and events during this year, which will be held by Qatari youth.
He also stressed that Doha – the capital of Islamic Youth 2019 will be an opportunity to promote rapprochement among young people in Islamic countries and build dialogue and will promote exchange of experiences among young people that will empower them in the Islamic world.
Source: Peninsula Qatar
Qatar grants Somalia $20m to support budget
Somali president to meet Qatari emir on bilateral…
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Kenya: Muslim organisations launch appeal for…


A nice atmosphere, really tasty cocktails, quick service, a good variety on the tapas menu. . בהחלט המקום המועדף עלינו!
Great place and even better service!
Get quick answers from Andalucia staff and past visitors.


text:
Isabella de'Medici
Caroline P. Murphy
£10.9910.99GBP
ISBN 9780571230310 Format Paperback
Published 07/05/2009 Length 432 pages
Isabella de' Medici was the hostess of a glittering circle in Renaissance Florence. Beautiful and liberated, she not only matched the intellectual accomplishments of her male contemporaries, but sought sexual parity also, engaging in an adulterous affair with her husband's cousin. It was this affair - and her very success as First Lady of Florence - that led to her death at the hands of her husband at the age of just thirty-four. She left behind a remarkable story, and as her legacy a son who became the best of the Orsini Dukes, immortalised by Shakespeare as Duke Orsino in Twelfth Night. Caroline P. Murphy illuminates this often misunderstood figure, and in the process brings to life the home of creativity, the city of Florence itself.
About Caroline P. Murphy
Caroline P. Murphy is a cultural historian and biographer. She is the author of Lavinia Fontana: A Painter and Her Patrons in Sixteenth-century Bologna, praised by Sarah Bradford in the Literary Review for 'shed[ding] new light on the ground-breaking career of a brave and talented woman.' Her second book, The Pope's Daughter, was described as a "remarkable biography" by the Daily Telegraph. Her most recent book is Isabella de'Medici. She grew up in Reading, studied art history at University College London, and now lives in Cambridge, Massachusetts.


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Monsterpocalypse Review
Written by GTP
Category: Playing
Monsterpocalypse has arrived! I have been anxiously awaiting the arrival of this game since I saw it announced. I love the Kaiju monster battle theme and liked the pre-released images I saw of the game. King of Tokyo and King of New York have been favorite board games of myself and my children for years now. The idea of transforming the board game experience into a miniatures game was very exciting for us. I even ordered the special GenCon exclusive Cthugrosh monster miniature off Privateer Press's website. But I have now gotten the two starter sets and built the models. My children have played their first game against each other (with me cheering both of them on) this evening. The first game took about 2 hours for my children to complete (subsequent games should be much faster). It was a down-to-the-wire finish with both of their monsters down to one health point a piece. They were holding their breaths on the final dice roll my son made. If he didn't make the roll and win, his sister was sure to make her roll on the next turn and win with her fully powered up monster... He happened to be ganging up all four of his small units with weapons on her monster, because his own monster was out of power (dice)... Units are extremely weak compared to monsters... It was anything but a sure thing...
So here are my detailed thoughts on the game.
Each player needs a starter set. Each starter set comes with 1 monster (either a Planet Eater or a GUARD monster) and 5 units of its faction. The models are made of resin, which is a soft plastic. The monster models definitely need to be trimmed and filed/ sanded before they are ready to be glued together with super glue. However, due to the fact that they are resin, this is fairly painless. They only have a few pieces each to glue together. All told it is a perfect experience for a beginning miniature gamer to practice building miniatures. The parts are big and chunky and go together easily. I also ordered the GenCon exclusive Cthugrosh monster and that had the same ease of assembly. In the Protector starter the units have to have their turrets glued on as well. In the Destroyer Starter the units are fully assembled already. The models are very cute and cool at the same time and look like they will be fun to paint. The bases for the models are clear plastic so they look pretty cool. We're waiting to glue the models to the bases until after we have painted them.
The starter sets also come with 6 cardboard apartment buildings, a double-sided paper game map mat, dice, a softcover rulebook, and cardboard rubble tiles. The rulebook is well layed out and very easy to read and understand. The cardboard and paper components are of standard modern game quality.
Players will choose one of two sides, Protectors or Destroyers. Each side has three factions on it that can be combined together. The Protector side has the G.U.A.R.D faction that comes in the starter, the Sun Syndicate (a ninja faction with a giant ninja as the monster), and the Terrasaurs (dinosaurs or Godzilla type creatures). The Destroyer side has the Planet Eaters that come in the starter, flying saucer Martians, and a Cthulu clone group. You can play a battle with 1, 2, or 3 monsters per side. The rule is that the monsters cannot be duplicates if you have 2 or 3 on your side. So basically, you need every model for your side if you want to play the biggest possible game. If you play with 1 monster you are allowed to have 15 units in your force. With 2 monsters you can have 20, and with 3 monsters you can have 25 units. Each faction comes with two different unit packs of 5 units each. So, doing the math... that's 6 unit packs for each side for a total of 30 units as options for the 25 slots available in a 3 monster battle. Note that the starters each come with one pack of 5 units for the side of the starter. That means there are 5 unit packs left to buy for your side after you get the starter.
Buildings in this game matter as well. The rules state that each player in a match must bring from 6 to 12 of her own buildings to the match. The starter sets give you 6 cardboard apartments each. The apartments are generic buildings with no special features. Building miniatures are coming out however and they will have special game features to them. These special buildings appear to be limited to 4 copies per side in an official game. Since the cardboard apartments are generic, there is no limit to how many of them you can bring to a match.
The rules for Monsterpocalypse are fairly simple compared to other miniatures games out there, but they are highly thematic with some unique and fun twists. The rulebook is extremely easy to read and understand. Like most miniatures games you have melee ("Brawl"), ranged ("Blast"), and special ("Power") attacks. Your monsters and units have a defense score and a speed score (which tells how far they can move. In order to attack another unit, building, or monster you roll three different colors of dice. White is the weakest dice, blue is middling, and red dice are the most powerful. You simply count up the explosions showing on the dice you roll and see if the total equals or exceeds the defense of the thing you are attacking. If you succeed you do one point of damage. Buildings and units only take one damage before they are destroyed. When buildings get destroyed they turn into fiery rubble that causes damage to anything that lands on it. Monsters have a health track on their cards that starts at 11 health points. The goal is to whittle all the opponent's monster's health points down to 0. All of that is pretty standard miniatures game stuff.
At this point, however, the game gets thematic and original with the twists it starts adding. First of all, the monsters have two forms. When their health is full they start in their "alpha" state. But when their health falls to 5 and below, their card flips over, and they go into a "hyper" state. In other words, they get very angry and become more powerful as they get injured. Very cool...
Then there is the dice usage twist. Each player gets 10 weak white dice. At least one of these dice must be used every time an attack is made by a monster or a unit. When a monster uses a white dice, that die then gets put over into the unit box to be only used by units on a subsequent turn. Conversely, when a unit uses white die, the die gets put into the monster box to be used by the monster after that. Thus, the white dice end up shuttled back and forth between the units and the monsters on different turns. This ensures that you can't just move your monster every turn and ignore your units for the game or vice versa. This give and take of the white dice between monsters and units adds a very slick extra element of strategy to your calculations during the game. Blue dice are just free to use based on the stats of the monster or units. The powerful red dice must be earned, however. You can earn red dice by destroying buildings, controlling buildings, controlling power points on the map, and killing units. Not only are the red dice filled with the most explosions, but they also are required for your monster to do its "Power" moves.
The Power moves are my and my children's favorite aspect of the game. This is where the game kicks the theme into overdrive. There are 6 fun moves available to each monster if they have the requisite red dice to spend. The moves are body slam, ram, rampage, stomp, swat, and throw. With body slam your monster can pick up your opponent's monster and smash it down on top of an adjacent building, unit, or any combination thereof. Your monster can use ram to charge into a building and topple it over onto a monster or units on the opposite side of it. With rampage your monster can charge forward its maximum allowable movement, flattening everything in its path. With a stomp your monster can blow up all adjacent units and put out building rubble fires. Your monster can swat an enemy unit and send it flying into another monster or unit. And, perhaps the most fun of all, your monster can pick up an enemy monster and throw it into buildings and units! It's when you do a power move and smash a monster into other things on the board that you start doing multiple points of damage at a time. We love these power moves. My children were laughing and giggling non-stop as they executed these moves on each other's monster.
Well, as I've already mentioned throughout the review, this game is an absolute hit with myself and my children. It is a hilarious good time. We can't wait for the other monsters, units, and buildings to be released. Both my children rate the game as a 9 out of 10 so far. The only other game they've rated that high is Krosmaster Arena. However, they both say they expect their rating will increase to a 10 after the new monsters come out for their armies. For myself, I'm going to just go ahead and give it a 10. I don't see how it can be any less than that once all the units, buildings, and monsters come out. Both my children have decided to field Protector armies and so I will be fielding a Destroyer army. We're all busy pondering what color scheme we're going to use when painting our monster armies now. For board gamers who haven't dipped a toe in miniatures yet, I would describe this game as the fulfillment of what King of Tokyo strives to be. We love King of Tokyo and King of New York. But this game truly epitomizes monster combat on the tabletop in a way that just hasn't been achieved to this level before.
Parent/ Teacher Recommendations
This game is appropriate for any children from about age 8 and up if the younger ones have a parent that can put the models together for them. Using super glue and snips is best left to parents for elementary school kids. However, once the models are assembled they are really a good size to allow children to learn to paint. They are chunky and yet detailed at the same time. Beginning miniatures-playing children would have a blast painting them. The rules are simple enough and thematic enough that 8-year olds with a bit of game playing experience should have no problem picking them up. Obviously, children won't be able to beat adult strategists at the game, but they can certainly play each other with the same alacrity they could show in playing chess with each other.
I'm going to introduce this game to my afterschool gaming club that I do at the elementary school I teach at. It's perfectly school appropriate for such a purpose. There is a lot of strategic thought being generated in the player's heads during this game. The strategic depth of the game is limited only by the players themselves. This particular miniature game has less mental math happening than other miniatures or role-playing games, however. There's nothing in this game beyond counting up explosion symbols on dice in that regard. So, this would be a good fit for students that might struggle with games that have more mental math.
To sum up, GO BUY THIS GAME NOW!
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Tag Archives: motion
Bindu Point
November 5, 2008 Martin	Leave a comment
Motion triggered audio/video performance
For 18 months from mid 2004 through to the end of 2005, I worked with performer,Lee Adams on this project after being awarded a research and development grant from Arts Council England.
The basic concept was to use video motion tracking to produce a responsive sound field, and as we developed the project, this became a sound source that I could improvise with and shape using various software and hardware controls.
Rather than being a purely academic exercise, we sought to produce an engaging, dynamic performance piece as well as explore some of the possiblities of using digital media in the performance arena.
This was my first large project using Max/MSP to build a software system, but before we go into the technical steps, here's a movie of the performance to give the idea of the experience.
Video Downloads:
Performance at Sonorities Festival, SARC, Belfast (QuickTime MOV 7.9mb)
Early performance video edited for ePerformance & Plugins Festival, Sydney, Aus. (QuickTime MOV 28mb)
Generative Output
This images shows the interface of the final application, combining the generative output principle of the original system with some live performance controls that I could use to modify the sound output.
I used the Cyclops external from Cycling 74 to provide the motion tracking with one of the Apple iSight FW cameras viewing the performance space. The hotspots provided by Cyclops are configured to output a midi note number when movement is detected in any of five zones. Every two note values are then converted to their binary equivalents and become 'parent' values. These 'parents' are fed to a logical operator that responds by flipping the value to 1 if either input is nonzero, or otherwise returning zero. The outcome of this is that a unique 'child' value is generated, which is then fed to a Korg Triton synthesiser and the software Wavestation built into the app.
Control screen for the "Bindu Point" Max patch
I wanted to be able to get my hands on and mix the sound, so the outputs from the two sound sources were run through a small mixer with an effects unit patched in.The new performance controls enable me to add sustain, pitch shifting and to change the velocity of each note in real time. As the performance grows, the sound builds into an evolving field of layered drones that the performer simultaneously creates and responds to.
During rehearsals, we added video feedback to the system, by projecting the trigger image back into the space and tuning the camera position to the point where it would respond to the changing light levels with chaotic, swirling images of the performance. This is probably no revelation to video artists, but in performance, it provided a spectacular visualisation of the audio output.
With this system, I wanted to address the issue of media-tised performance, so there were no screens or artificial barriers between us and the audience. It's a purely experiential performance that makes use of technology to augment the human experience, and although the audio output certainly leads what I could do, it allows the human element to take the lead and initiate each stage, as well as respond to the audio and video outputs.
I began the first stage of this project in 2003 when I was studying for my MA and made a movie of Lee Adams using the first version of the system at Bow Arts Trust in East London. The movie is packaged as a skinned QuickTime, called "Telecommunication" (20mb ZIP)
bindu pointLee AdamsmotionperformanceSARCtracking


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FDA Discovers Autoimmune Mechanism for Drug Reactions
New hope for drug development in identifying adverse drug reactions
May 23, 2012 / Author: Staff / Reviewed by: Natasha Levin
A team of researchers led by the U.S. Food and Drug Administration has discovered a new mechanism for identifying and understanding drug-related autoimmune reactions.
In an article available online today in the journal AIDS , the team found that in certain at-risk patients, the anti-HIV drug Ziagen (abacavir" data-scaytid="3">abacavir) causes the immune system to "see" a patient's own healthy tissues and proteins as foreign invaders.
The effect is similar to what happens when the immune system recognizes a viral or bacterial protein during an infection.
Abacavir is known to cause allergic reactions in certain at-risk patients. These reactions can range from mild skin reactions to severe allergic shock and even death.
Abacavir interacts with molecules in the immune system called human leukocyte antigens (HLAs), specifically HLA-B*5701, which help the body to distinguish "self" versus "foreign" proteins. The drug can cause HLA-B*5701 to present for the first time certain "self" proteins that the body has not seen before.
Because the body has not previously recognized these "self" proteins, it mistakenly treats them as foreign, resulting in the body trying to destroy its own tissues. HLA-B*5701 is known to be a risk factor for serious reactions to abacavir.
"This discovery is a new step towards understanding how and why certain drugs cause severe allergic reactions in some patients," said Janet Woodcock, MD, director of FDA's Center for Drug Evaluation and Research (CDER).
"We hope that, in the future, health care professionals will be able to identify people who are at high risk of developing serious reactions to various drugs, and offer them alternative treatments."
The research team's work will provide the FDA with new tools to analyze the safety of drugs that have the potential to cause severe allergic reactions. This latest discovery will advance the FDA's ability to approve therapies that are personalized for safety.
The results also may give biopharmaceutical companies and other research organizations new methods to identify early in the development process drugs with the potential to cause severe adverse drug reactions.
This may also serve as a model for future research to predict drug reactions in different populations of at-risk patients.
The research team was led by Michael Norcross, MD, of the Office of Pharmaceutical Sciences in CDER.
HIV AIDS Sexually Transmitted Disease Infectious Disease Patient Safety Education Rheumatic Disease
Natasha Levin
Avoiding Drug Interactions
New Rx for Women Gets Green Light
FDA Calls Out Canadian Company
It's Test Day: Get Tested for HIV
Knowing the Options: HIV/AIDS Testing
How to Prevent the Spread of HIV
NBA Stars Who Give Back
Tips for Women with HIV AIDS
The human immunodeficiency virus (HIV) kills or damages the body's immune system. By damaging your immune system, HIV interferes with your body's ability to fight the organisms that cause disease. As the immune system weakens, the body is ...
More about Human Immunodeficiency Virus (HIV)
HIV AIDSGonorrheaSexually Transmitted DiseaseSyphilisSexually Transmitted DiseaseSexually Transmitted DiseaseHerpes Sexually Transmitted DiseaseSexually Transmitted DiseaseHepatitis
Emtricitabine & Tenofovir AtazanavirRitonavirLopinavir & RitonavirAbacavir & LamivudineEfavirenz & Emtricitabine & TenofovirDidanosineVidex ECNevirapineTipranavir


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