Cell Medica announces the treatment of the first patient world-wide to receive CMD-501, an autologous CAR-NKT therapy targeting pediatric neuroblastoma. This is the first time an engineered NKT cell therapy has been used in humans. Cell Medica is a clinical-stage biopharmaceutical company that is transforming the treatment of solid and hematological cancer by developing the next generation of CAR therapies.
This open-label Phase 1 study, GINAKIT2, is being carried out in collaboration with both Baylor College of Medicine (BCM) and Texas Children's Hospital.
CMD-501 is based on Cell Medica's novel CAR-NKT platform, a next-generation technology of engineered immune cells with enhanced functions for the treatment of hematological and solid tumors, utilizing the unique properties of NKT cells, a specialized type of innate lymphocytes, sharing properties of T and NK cells. CMD-501 is the initial study from Cell Medica's CAR-NKT pipeline and utilizes an autologous approach. The patient's own NKT cells are genetically engineered with a CAR targeting GD2, a molecule expressed on the surface of nearly all neuroblastoma cells. In collaboration with its partners at BCM and Texas Children's, Cell Medica designed this CAR-NKT cell therapy to also secrete the cytokine IL-15, which has been shown in pre-clinical studies to increase the persistence of CAR-NKT cells and improve their efficacy within the immunosuppressive tumor microenvironment.
GINAKIT2 is a first-in-human, dose escalation evaluation of CMD-501 in children with relapsed or refractory (R/R) high-risk neuroblastoma, (NCT03294954). Neuroblastomas occur primarily in children and account for 7-10 percent of all pediatric cancers. Ninety percent of patients are younger than 5 years at diagnosis. R/R high risk neuroblastoma is one of the deadliest types of childhood cancer and the current median survival is around 1-3 years. Almost all neuroblastomas express GD2, which is targeted by CMD-501. This study is supported by a grant from Alex's Lemonade Stand Foundation (ALSF), awarded to BCM investigators, Drs. Heczey and Metelitsa.
Neuroblastoma is a cancer of the sympathetic nervous system which can occur in the chest, neck, abdomen and adrenal glands, and can metastasize to the bone marrow and other organs. Children with low or intermediate risk neuroblastoma can be cured through surgical intervention and/or chemotherapy, however, at least half of all children with neuroblastoma have high risk disease, which often requires combined surgical, radio-, immuno-, and chemotherapy, in addition to autologous stem cell transplantation. Patients with relapsed/refractory high-risk neuroblastoma have one of the deadliest types of childhood cancer and a poor prognosis, with median survival of 1-3 years.
GD2 is a molecule expressed on tumors of neuroectodermal origin, including almost all neuroblastomas, and a substantial fraction of small cell lung cancer and melanoma, with restricted expression on normal tissues, making it a good target for CAR-NKT cell therapy.
CMD-501 is an innovative autologous product in which NKT cells are genetically engineered with a CAR targeting GD2. NKT cells are a subset of T lymphocyte with the cytotoxic and anti-tumor properties of conventional T cells, but with other biological attributes that are expected to improve their ability to attack tumors. GD2 is a molecule expressed on the surface of most neuroblastoma cells.
In collaboration with its partners at BCM, Cell Medica has engineered a GD2-specific CAR construct that is additionally designed to secrete the cytokine IL-15, which has been shown in pre-clinical studies to increase the persistence of CAR-NKT cells and improve their efficacy within the immunosuppressive tumor microenvironment. CMD-501 is an autologous product, meaning that each patient's own cells are collected, modified and activated outside the body, and then infused back into the same patient. However, NKT cells also have significant potential for so-called off-the-shelf use, where cells from a healthy donor could be prepared in large quantities in advance and used to treat many different patients. Cell Medica is collaborating with BCM to bring an off-the-shelf CAR-NKT cell product into the clinic in the near future.
Cell Medica is a clinical-stage biopharmaceutical company focused on transforming the treatment of solid and hematological cancer by developing next generation CAR-T therapies. Developing both allogeneic and autologous therapies, the company's revolutionary platform engineers chimeric antigen receptors (CARs) on Natural Killer T cells (NKTs), a subset of T lymphocytes. A robust pipeline is being created in partnership with the Baylor College of Medicine, Texas Children's Hospital and University College London. Headquartered in London, the company also has facilities in Houston and Zurich.
Baylor College of Medicine in Houston is recognized as a premier academic health sciences center and is known for excellence in education, research and patient care. It is the only private medical school in the greater southwest and is ranked 16th among medical schools for research and 5th for primary care by U.S. News & World Report. Baylor is listed 20th among all U.S. medical schools for National Institutes of Health funding and number one in Texas. Located in the Texas Medical Center, Baylor has affiliations with seven teaching hospitals and jointly owns and operates Baylor St. Luke's Medical Center, part of CHI St. Luke's Health. Currently, Baylor trains more than 3,000 medical, graduate, nurse anesthesia, physician assistant and orthotics students, as well as residents and post-doctoral fellows. Follow Baylor College of Medicine on Facebook and Twitter.


text:
Boston Herald Newspaper Photograph Collection
Photographs, circa 1880-1972. Primarily 8" x 10" black-and-white prints. Images made by Boston Herald photographers and the Associated Press wire services, featuring John F. Kennedy and the Kennedy family at various events during his tenure as Congressman through his presidency. Also included are historic family photographs as well as images of John F. Kennedy's assassination and memorial services, Jacqueline Kennedy's life through 1969, and the creation of the John F. Kennedy Presidential Library.
Boston Globe Photograph Collection
Photographs, circa 1897-1962, created and collected for publication in The Boston Globe. Photographs include early images of the John F. Fitzgerald family, the Joseph P. Kennedy family, and John F. Kennedy from childhood through his tenure as Congressman.
Kennedy Family Collection
Photographs, 1878-1980 (bulk 1890-1965). Images of the John F. Fitzgerald Family, the Patrick Joseph Kennedy Family, the Joseph P. Kennedy, Sr., Family, and their friends and associates.
David E. Koskoff Personal Papers
Papers 1938-74 (bulk 1938-1940). Lawyer. Author, Joseph P. Kennedy, a Life and Times (1974). Correspondence, printed materials, interview notes, background material, index cards, and drafts. Includes a copy of James Landis' manuscript biography, Joseph P. Kennedy .
James W. D. Seymour Personal Papers
Papers, 1919-1972 [Bulk 1938-1940]. Secretary and press attaché to Ambassador Joseph P. Kennedy, 1938-1940. Correspondence, copies of Kennedy's speeches, newspaper clippings, press releases and radio messages, pamphlets, luncheon/dinner invitations, and other items.
Beulah Harris Ignall Photograph Collection
Photographs, 1953-1960. Photographic negatives and prints of three Kennedy family weddings: Eunice Kennedy/R. Sargent Shriver, Patricia Kennedy/Peter Lawford, and Jean Kennedy/Stephen Smith. The collection also contains images of a reception hosted by Grant Stockdale for Senator John F. Kennedy.
William Flick Personal Papers
West Point cadet (1949-1951). Letters, clippings and photos related to West Point cheating scandal.
Paul F. De Gara Personal Papers
Records 1956-1971. Medical files of Doctor Paul F. de Gara, an allergy and immunology expert whose patients included John F. Kennedy, Rose Kennedy, and Joseph P. Kennedy.
Magnum Photos Collection
Photographs, 1939-1968. 35mm and 4" x 5" black and white contact sheets, one silver-gelatin print, one reel 35mm negative microfilm. Images made by Magnum Photos, Inc. photographers, featuring John F. Kennedy, Robert F. Kennedy, members of the Kennedy family, and their associates.
Joseph P. Kennedy Personal Papers
Papers, 1888-1974. Father of President John F. Kennedy, banker, financier, diplomat. Chairman, Securities and Exchange Commission (1934-1935); Chairman, U. S. Maritime Commission (1937-1938); Ambassador to Great Britain (1938-1940). Personal, family, business, and diplomatic papers.
(-)Collection (11)
Diplomatic and consular service (3)
Monuments and memorials (1)
(-)Kennedy, Joseph P. (Joseph Patrick), 1888-1969 (11)
Lawford, Patricia Kennedy, 1924-2006 (5)
Kennedy, Ethel (Ethel Skakel), 1928- (3)
de Gara, Paul F. (Paul Frederick), 1902-1991 (1)
Evans, Arthur Reginald, 1905-1989 (1)
Fitzgerald, Mary Josephine Hannon, 1865-1964 (1)
Flick, William, 1931-1998 (1)
Jackson, Henry M. (Henry Martin), 1912-1983 (1)
Kennedy, Caroline B. (Caroline Bouvier), 1957- (1)
Kennedy, Patrick Bouvier, 1963 (1)
Kennedy, Patrick Joseph, 1858-1929 (1)
Koskoff, David E. (David Elihu), 1939- (1)
Lawford, Peter (Peter Sidney Vaughn), 1923-1984 (1)
Seymour, James W. D. (James William Davenport), 1895-1976 (1)
Shriver, Sargent (Robert Sargent), 1915-2011 (1)
Sinatra, Frank, (Francis Albert), 1915-1998 (1)
Smith, Stephen E. (Stephen Edward), 1927-1990 (1)
Stockdale, Edward G. (Edward Grant), 1915-1963 (1)
London (England) (2)
Boston Globe (Newspaper) (1)
Boston Herald (Newspaper) (1)
Magnum Photos, Inc. (1)
United States. Air Force (1)
United States. Army. Military Academy (1)
Waldorf-Astoria Hotel (New York, N.Y.) (1)

redpajama_set_name: RedPajamaCommonCrawl


text:
Q: Ruby on Rails: putting class with submit_tag I was wondering why we have to add a nil when putting :class => "class_name"
<%= submit_tag nil, :class => "class_name" %>

but for this:
<%= f.submit class: "class-Name" %>

I don't need to add the nil
Thanks

A: A look to the way that submit_tag method was implemented clearly answers your question.
  def submit_tag(value = "Save changes", options = {})
    options = options.stringify_keys

    if disable_with = options.delete("disable_with")
      options["data-disable-with"] = disable_with
    end

    if confirm = options.delete("confirm")
      options["data-confirm"] = confirm
    end

    tag :input, { "type" => "submit", "name" => "commit", "value" => value }.update(options)
  end

It takes two arguments, the first is value which by default is "Save changes" and the second is a Hash of options. If you don't pass nil then it will assume that that's the value you want for the input.

A:      <%= submit_tag("Update", :id=>"button", :class=>"Test", :name=>"submit") %>

First parameter is required and it would be value and they any parameter you want to specify, can be done in a hash like :key=>"value".

A: Because they are two different methods...
The "submit" method doesn't take a caption because it can infer one from the form that the method is called on, and what object was used to build the form.
The "submit_tag" method is not called on a form object.  It is used for more customized form building (more separated from your activerecord model, for example) and so the code can't infer a caption and must get a value as the first argument.  All the "formelement_tag" methods (documented here, for example) are like this and can infer less based on your data model.

A: Obvious answer is that submit_tag and submit are simply different form helper methods that takes different arguments.

A: The _tag series of methods usually require a name parameter (otherwise they'd be fairly useless tags, so it's always the first argument instead of part of the hash. Because the submit helper is called as part of the form, Rails can assume the field's name property and can then make the options hash the first argument.

redpajama_set_name: RedPajamaStackExchange


text:
Disease Category: Sleep
Clinical Relevance
Developer: Runtastic
Cost: Free; Free with in-app purchases
Functionality: Display data, Inform/Educate, Provide insights, Record user-entered data, Reminder/Alerts
Sleep Better by Runtastic is one piece of the Runtastic suite seeking to improve patients lives through health and fitness inputs. The premise of the app is that users can simply lay their phone next to themselves while they sleep to help track their sleep pattern based on movement sensed via the accelerometer in the phone. This data is this collated and assessed to identify sleep patterns and how 'well' the user is sleeping. The app will then wake the user up via an alarm based on the time set by the user, based on sensing when the user is most restless.
While the app is easy to use, and practical in approach, it does have several shortcomings noted during review. One large issue is that the app did not wake the reviewer up several times when tested, though did log the sleep record from the night.
Sleep Better is intended to track sleep, awake the user at the 'right time' and feeling more refreshed, and assess dream states during sleep. The app is targeted at users who are looking for a passive mechanism to track their sleep. The premise is that their phone can be placed next to them while they sleep, and that the sensors on the phone will pick up movement, and also aim to help wake the user at the best possible time in the morning.
This app will be useful for patients that are looking to assess their quality of sleep, and for a 'smarter' alarm clock that wake them up at the best possible time. If a user is already using Runtastic apps for their exercise and health tracking, this app will work well into that suite to collate the data together. In summary, consumers interested in health and fitness, and also those asked to monitor their sleep.
How should use it?
Ideally, this app can be used to help users track factors that may impact their sleep (e.g. coffee consumption, exercise) via use of other runtastic apps. The app premise is rather simple to use, as it only requires being laid on the bed to sense movement. However, as noted by this reviewer, a mattress that reduces movement sensation to partners (e.g. tempurpedic mattress) may equally lead to less movement being sensed by the phone to get an accurate measurement of sleep/movement pattern at night. The user should use the app consistently for 2-3 weeks to get a good sense of their sleeping habits and for the app to learn the user's behavior.
Is the mobile app clinically relevant? Any clinical benefits? How would you use it as a provider?
For users who have difficulty sleeping, and looking to track their sleep patterns, this app may be beneficial. Ideally, the app will help identify daily patterns that are inputed by the user, and help identify trends in poor sleep, based on movement assessment while the user sleep. Secondary to that, the app aims to help wake the user during a set time-frame preselected by the user, based on sensing when the user is nearly awake.
The benefits of this data could be to help the user become self-aware of sleep patterns or habits requiring alteration, and may serve as a better alarm clock for the user. However, based on this reviewers experience, there were several instances where the alarm never went off as set, and the reviewers back-up alarm was triggered instead.
While their have been several reviews on the Runtastic Pro app for exercise in the literature, there are currently none available on the app under consideration – Sleep Better. However, what's quite concerning is that a similar app (Sleep Time by Azumio, which uses similar mechanics to track sleep via movement, like Sleep Better) was studied in a small cohort in comparison to polysomnography (PSG), which found no relationship to tracking actual sleep data and correlated poorly with PSG. Even thought there is no data that this particular app is effective, there is good data that waking up at right state is helpful with dream states.
Not FDA cleared; most likely exempt under new FDA mobile medical application guidance.
The app is fairly easy to use and set up, requiring the user only to input certain data related to their daily activities prior to sleep, and then placing it on their bed after setting an alarm for the morning. Interpreting the data is fairly straightforward, but would be unlikely to give much benefit only after several uses, and is intended for multiple nights to build up significant data. The interface is very nice and has clear graphics.
How does this app compare to others in the category?
Currently, based on other apps and lack of integration to wearables, would say that the app is similar to other apps on the market that purport to track sleep via movement on the bed. Otherwise the only item that makes this app stand out is whether a user likes the interface, or is already using Runtastic in their daily lives.
In-app purchases, but no separate paid app. The full version gets rid of the in-app adds that can be bothersome to have to sit through at times, unlocks further sounds for alarms, add a dream journal, and allows for more analysis on 'sleep influences' such as diet, exercise, drinking habits, and lastly, connect with lunar phases.
Password: No password
Ayesha Khalid
Ayesha is an ENT surgeon at Harvard Medical School with an MBA in Global Leadership and Innovation from the MIT Sloan School of Management. Ayesha serves on several Boards for medical organizations and is currently on the board of the American Academy of Otolaryngology- Head and Neck Surgery. Ayesha has experience with consulting for private equity firms to evaluate business opportunities in the health IT and medical practice management. She served as Vice-President of Business Development of a digital health start-up out of Johns Hopkins, Doctella. Presently, in addition to clinical practice, Ayes is the Clinician Director for CBIT at the Yale School of Medicine and is curating early stage health IT startups. You can follow Ayesha on Twitter at @ayeshakhalidmd
Employment: Cambridge Hospital and Harvard Medical School; Yale School of Medicine; Consultant/ Advisor: 480 Biomedical, Stallergenes Greer, Smith and Nephew, Lambay Advisors, Burr Pilgrim Mayer; Ownership: 480 Biomedical, Collective Healthtech, GeoHealth
MotionX 24/7
Sleep Pulse 2


Film Director Amit Gupta recently asked me to do a few portraits of him for his press releases. We spent 15 minutes together getting a few pictures and he recently contacted me to tell me his portrait is in Empire magazine and also one now online.
Amit's first film that he directed was called Resistance and was set in a Welsh village in WWII, imagining life had the Germans invaded. With a cast including Michael Sheen it is a brilliant art house film and is well worth a watch.
Amit's latest film I am looking forward to watching is Jadoo the Movie, a British comedy that takes Amit back to his roots of growing up in Leicester. Its about two brothers who are chefs & what happens when they fall out. They set up rival restaurants across the road from each other in the Belgrave Road in Leicester, close to where Amit grew up.
I can't say anymore than that but in the same vein as previous posts I will be attending the Lemongrove gallery, Henley this Sunday with my lovely wife (she's the manager of the gallery!) for another artist apprearance.
As i said I can't say any more than that except I will be taking my camera and wobble board?
Can you tell who it is yet???
Not content with one Lemongrove event last week I was back in Reading last Saturday to photograph the Todd White event. As popular as ever the gallery was very busy with collectors of his work many of whom got to meet him and many a lucky fan got a characature drawn of themselves by the man himself. Those of you unfamiliar with Todd's work please click here.
To my surprise he was the illustrator for Spongebob Squarepants, a familiar character for those younger people out there. There were a few children at the event that left with a beaming smile on their face and a Spongebob sketch under their arm.
Here are a few of my favourite images from the event….
Mr Lord with Mr White and a sketch!


Owning and using a small rv is more popular than ever -- and for a good reason. There has never been a better selection of small recreational vehicles to choose from than the current crop of RVs. Small RVs allow you to go almost anywhere -- from the smallest class B that drives like an SUV, to the largest Class C small RV that has most of the features of the big Class A RVs. There is an RV to meet almost any lifestyle and budget.
The first decision when you are thinking about buying an RV is whether to get a motorized RV or a towable RV.
There are several options to choose from when picking out an RV or motorhome. Motorized RVs come in three main selections: class A, class B, and class C. It is important to decide which class of RV will best suit your needs before making a purchase.
Class A motorhomes are typically the most expensive RVs and are usually not in the class of a small rv. They have a long, bus-like frame and come with about every home feature imaginable. They are built right onto a truck chassis and are usually between thirty and fifty feet long. A lot of today's Class A RVs have slide-outs, which make the units a lot wider with just pressing a button. You can get options such as washers and dryers, hot tubs, and flat screen TVs. They can make any camping trip a luxurious one. Many owners of Class A RVs choose to tow a car behind the motorhome so that when they get to their destination, they can hook up their RVs, and take off to enjoy the sights their destination has to offer in the privacy of their own (towed) cars.
Class B RVs are much like a camper van. They are less expensive then the class A models, but also have less features. While the class A models feature four of the following features, class B models only have two: kitchen and toilet facilities, city water hook up, sleeping, freshwater storage, 100-volt hookup, and top extension. A Class B RV would be perfect for an overnight camping trip. The really great thing about the Class B RV is that it can be used to toot around your destination. The Class B is not as wide as the other classes of RVs, so it is easy to park and drive through cities. Some of the Class Bs have dropped floors, and others have raised roofs, which make standing and walking a comfort.
Class C models are very similar to class A motorhomes. The difference between the two is that class A motorhomes are built on the same motorized chassis. Class C RVs have a separate living compartment from the cab section. They are like mini, less expensive motorhomes. Although not as expensive as the Class A models, the Class C RVs have all four of the main requirements for making a journey in comfort and style: sleeping areas, living areas that include dining facilities, full bathroom amenities, and also kitchens that make meal preparations a breeze. A lot of the Class Cs have slide-outs, which are areas that can extend to make the living space even larger than it is. And, the slide-outs are as easy as pushing a light switch!
As with the motorized RVs, there are several options when picking the towable RVs. The towable RVs are those that are towed by a motorized vehicle. Towable RVs come in four selections: the Fifth Wheel, the Truck Camper, the Pop Up, and the Travel Trailer.
The Fifth Wheel RV is attached on top of a truck with a fifth wheel hitch. Because it is attached to the truck rather than pulled by it, it is easier to maneuver than an RV trailer that is simply pulled by a towing hitch. These RVs provide a lot of space and amenities for a lower price than a motorized RV. Once you hook them up at your destination, they quickly become your home away from home. Most of the new models include at least one slide-out, which adds extra living space to living areas. You will have a difficult time deciding what area of your home on wheels you want the slide-out to make larger. Will it be your living room, bedroom, or perhaps even your kitchen?
The Travel Trailer RV is able to be pulled by a van, truck, SUV, or even your car, since it doesn't necessitate a special wheel hitch that is permanently embedded in the back of a truck (like the Fifth Wheel has.) Imagine reaching your destination and simply unhooking your travel trailer, and taking off to enjoy your vacation in the same vehicle you pulled your "home" with! There are so many floor plans available, and many include those wonderful slide-outs!
The Pop Up trailer is also called Folding Camper Trailer and Tent Trailer. The Pop Up has walls that are collapsible. Some say that they are the closest to camping outdoors, and that the Pop Up Trailer provide areas to sleep, eat, and play inside when the weather is wet and dreary.
This is a unit that goes directly on the bed of a truck. They are sometimes called Pick Up Campers. Companies that specialize in making Truck Campers are adding more options for prospective buyers to pick from. Its hard to believe that you can now include a shower in a truck camper, but that is just one of the many features that are now available.
When choosing RVs or motorhomes, it is important to choose one that fits your usage. An RV is only worth what you get out of it. A small RV and motorhome provide comfort tailored to your individual needs.


Bosworth Lake covers 105 surface acres and reaches a maximum depth of 79 feet. It is located at 563 feet of elevation. Fish species include rainbow and cutthroat trout and largemouth bass. The water is gin clear. Public access is provided by the Washington State Department of Fish and Wildlife. The access area has been update fairly recently with a new pit toilet and concrete boat launching ramp. No internal combustion engines are allowed on the lake.


The Trawalla Foundation works with individuals and organisations that have a vision for the future of Australian society.
The Trawalla Foundation works with exceptional individuals and organisations that have a vision for the future of Australia, focused on strengthening gender equality, creativity, sustainability and social justice within our society.
We adopt a range of levers including grants, investments, skills, networks and advocacy, to deepen the impact of the individuals and organisations that we work with.
Our investment values and approach guide who we invest or collaborate with, and the standards we hold ourselves to.
Social justice: upholding principles of equity, inclusiveness and fairness.
Our investment approach is: to work with an entrepreneurial mindset, demonstrating the progressive attitudes and ideas of multiple generations. We aim to be bold, curious and action oriented, and are willing to take intelligent risks alongside our partners. We focus on catalysing and growing new initiatives, business models and organisations.
Ultimately, create positive social, environmental and financial outcomes, and to strive for systems change.
We fund a range of organisations that align with our investment values and approach.
All of our Foundation corpus investments are managed with a responsible investing lens, including negative screenings (such as fossil fuels, alcohol, gambling, tobacco, animal welfare, firearms), and positive screenings (such as minimum 25 per cent of board directors must be women).
Please note: The Trawalla Foundation is a Private Ancillary Fund, which does not solicit funding requests from the public or have grant rounds.
Carol Schwartz is one of Australia's leading business identities. Carol has extensive experience in business, property, the arts and community organizations.
Carol's current roles include: Chair, Ourcommunity; Chair, Womens Leadership Institute Australia; Director, Stockland Ltd; Member, Reserve Bank Board; Director, Qualitas Property Partners.
Sarah brings fifteen years' leadership experience in the corporate and not-for-profit sectors, focused on social innovation and investment. Sarah was previously Consulting Director at PwC Australia, and GM at Opportunity Child. Alongside her work for Trawalla Foundation, Sarah consults to a range of companies and social sector organisations. Current advisory board roles include People Measures, Reach Enterprises and SVA's Diversified Impact Fund.
© Trawalla Group. All Rights Reserved. ABN: 26 161 068 625.


As of April 24, 2019 - Minimum 20 minute delay.
Arch Capital Group Ltd. (Arch Capital or ACGL), a Bermuda public limited liability company, writes insurance, reinsurance and mortgage insurance on a worldwide basis with a focus on specialty lines. The combination of our underwriting platform, our experienced management team and our strong capital base have enabled us to establish a prominent presence in the global insurance and reinsurance markets.
Maintain a disciplined underwriting approach to enable us to select risks and price them appropriately in all phases of the insurance cycle.
In March 2014, Watford Holdings Ltd. (Watford) raised approximately $1.1 billion of capital consisting of $907.3 million in common equity and $226.6 million in preference equity. Arch invested $100.0 million and owns 2,500,000 common shares, approximately 11% of Watford's outstanding common equity as of December 31, 2018, along with warrants to purchase up to 975,503 additional common shares. The warrants are exercisable and expire on March 31, 2020. Arch also holds 600,000 shares of Watford's cumulative redeemable preference shares. Under applicable accounting rules, 100% of Watford's results are included in Arch's consolidated financial statements. Watford's common shares are listed on the Nasdaq Select Global Market under the ticker symbol "WTRE" and its SEC filings and other financial information can be found here.


text:
Devout Christians should pose these questions to the pope
Other Languages German / DeutschDutch / NederlandsTurkish / Türkçe
The Human Miracle
Communication and Argument in the Qur'an
If Darwin Had Known about DNA
What Darwinists Fail To Consider
The Origin of Birds and Flight
The Miracles of Our Prophet (saas)
With a recent statement announcing the entire world that it has a moderate outlook on Darwin's evolution theory, Vatican claimed that the faith of creation in Christianity and biological evolution are complementary. With this statement indicating the Pope's point of view on Darwin, Vatican, the symbol of Christianity, has undertaken the patronage of an surprising, and even disturbing explanation.
In the face of these explanations that can never be reconciled with faith in Allah (God) and Christianity, it needs to be brought to light whether these extremely disturbing statements belong to Vatican or not. For this reason, DEVOUT CHRISTIANS SHOULD POSE THESE QUESTIONS TO THE POPE:
1. The entire world of Christianity and Islam await the descend of Prophet Jesus (pbuh). When Prophet Jesus (pbuh) comes, will you be able to look into his eyes and say, "You have come into being by evolution"?
2. Allah took Prophet Jesus (pbuh) into His sight. How will you explain his second coming to Earth by evolution?
3. According to your faith, did Gabriel [Jibril (pbuh)], Michael [Mikhail (pbuh)] and all the other angels stated in the New Testament and all the other holy books come into being by evolution?
4. Did the jinn stated in the Bible and the Qur'an come into being again by way of evolution?
5. Did satan come also into being by evolution?
6. Did Prophet Moses' (pbuh) staff, which immediately turned into an alive snake that had the ability to reproduce, come into being by way of evolution?
7. Did the bird Prophet Jesus (pbuh) make out of mud and made it alive by blowing on it come into being by evolution? (The Qur'an 3:49)
Devout Christians and press should pose all these questions to the Pope. Only the answers to these questions will have a validity for sincere people of faith. The press should accept the answers of these questions as the Vatican's statement, and not the statements given on Vatican's behalf. Consequently, without waiting for the answers of these questions, people should not give credit to the statements that appear in some press organs as the Pope's statements about evolution.
However, if these statements claimed to be made by Vatican were actually true, then the following conclusion emerges: freemasonry and atheist zionists make pressure on Papacy. If such a pressure by masons and atheist zionists were true, and the Pope were hindered from advocating the facts, then the situation is extremely serious. This simply means that the Darwinist dictatorship has no limits. It is also concluded that Vatican is made an instrument in this filthy plot and simply prevented from advocating and honestly telling the facts.
Yet it is an established fact that despite Darwinist dictatorship's filthy plots, people all over the world have realized that evolution is a fraud. They have learned that the number of fossils unearthed so far has exceeded 100 MILLION and NOT A SINGLE ONE OF THEM IS A TRANSITIONAL FORM. They have seen with proof that all of these are perfectly created living beings having perfect attributes, and even some of them represent LIVING FOSSILS dating millions of years. People have examined these proofs themselves. They have clearly seen that the prophecy Darwin made 150 years ago have come to be true. 150 years ago Darwin made the following prophecy in his book, The Origin of Species:
... Why, if species have descended from other species by insensibly fine gradations, do we not everywhere see innumerable transitional forms? Why is not all nature in confusion instead of the species being, as we see them, well defined? But, as by this theory innumerable transitional forms must have existed, why do we not find them embedded in countless numbers in the crust of the earth? Why then is not every geological formation and every stratum full of such intermediate links? Geology assuredly does not reveal any such finely graduated organic chain; and this, perhaps, is the most obvious and gravest objection which can be urged against my theory.[i]
In this statement Darwin confesses that transitional forms do not exist and that his theory would collapse in case they can not be uncovered. At present, in the 21st century, 100 MILLION FOSSILS HAVE BEEN UNEARTHED AND NOT A SINGLE ONE OF THEM IS A TRANSITIONAL FOSSIL. Almost all the earth have been dug up. Yet if it were possible and 100 MILLION MORE FOSSILS WERE UNEARTHED, AGAIN NOT A SINGLE FOSSIL WOULD BE FOUND. That is because THE THEORY OF EVOLUTION is a fraud, it is the BIGGEST MASS HOAX OF HISTORY that has influenced the entire world for 150 years.
People already know that THERE EXISTS NOTHING CALLED TRANSITIONAL FOSSIL, that PROTEINS COULD NOT HAVE COME INTO BEING BY CHANCE, that ALL THE SKULLS that Darwinists try to show as evidence for the imaginary evolution of human beings ARE FAKE. People also know that Darwinists make forgery, that THEY PRODUCE FAKE FOSSILS, and do not currently take offence at displaying them in museums. People already know that what is put forward as transitional forms are only speculations made on extinct species. For this reason, people do not give credit to lies of evolution. That Vatican accepts the theory of evolution and churches organize conferences about evolution will not change this fact. Today in Turkey the ratio of people believing in evolution is 5 percent, while in the United States it is 21 percent[ii], and in England, Darwin's mainland, it is only 25 percent[iii]. While this ratio increasingly decreases, people witness the demolition and disappearance of the theory of evolution, draw closer to faith and turn to All-Mighty Allah, the Creator of everything from nothing. The plots of masons and atheist zionists have definetly turned against themselves.
Angels in the Bible:
Daniel 8: 16 -17 And I heard a man's voice from the Ulai calling, "Gabriel, tell this man the meaning of the vision."
As he came near the place where I was standing, I was terrified and fell prostrate...
Daniel 9:21 While I was still in prayer, Gabriel, the man I had seen in the earlier vision, came to me in swift flight about the time of the evening sacrifice.
Luke 1:19 The angel answered, "I am Gabriel. I stand in the presence of God, and I have been sent to speak to you and to tell you this good news.
Luke 1:26-27 In the sixth month, God sent the angel Gabriel to Nazareth, a town in Galilee, to a virgin pledged to be married to a man named Joseph, a descendant of David. The virgin's name was Mary.
Jude 1:9 But even the archangel Michael, when he was disputing with the devil about the body of Moses, did not dare to bring a slanderous accusation against him...
Jinn in the Bible:
Deutoronomy, 32:17 They sacrificed to demons that were no gods, to gods they had never known,
to new gods that had come recently,
whom your fathers had never dreaded.
Psalm 106:37 They sacrificed their sons and their daughters to the demons;
Matthew 9:32 While they were going out, a man who was demon-possessed and could not talk was brought to Jesus.
Matthew 9:33 And when the demon was driven out, the man who had been mute spoke. The crowd was amazed and said, "Nothing like this has ever been seen in Israel."
Matthew 9:34 But the Pharisees said, "It is by the prince of demons that he drives out demons."
Luke 11:15 But some of them said, "By Beelzebub, the prince of demons, he is driving out demons."
Luke 11:19 Now if I drive out demons by Beelzebub, by whom do your followers drive them out? So then, they will be your judges.
Luke 11:20 But if I drive out demons by the finger of God, then the kingdom of God has come to you.
Luke 9:1 When Jesus had called the Twelve together, he gave them power and authority to drive out all demons and to cure diseases.
Luke 8:31 And they (demons) begged him [Jesus] repeatedly not to order them to go into the Abyss.
Matthew 17:18 Jesus rebuked the demon, and it came out of the boy, and he was healed from that moment.
Satan in the Bible:
1. Chronicles 21:1 Satan rose up against Israel and incited David to take a census of Israel.
Job 2:7 So satan went out from the presence of the Lord and afflicted Job with painful sores from the soles of his feet to the top of his head.
Matthew 4:10 Jesus said to him, "Away from me, satan! For it is written: "Worship the Lord your God, and serve him only."
Mark 3:26 And if satan opposes himself and is divided, he cannot stand; his end has come.
Mark 1:13 And he was in the desert forty days, being tempted by satan. He was with the wild animals, and angels attended him.
Luke 22:31 Simon, Simon, satan has asked to sift you[a] as wheat.
Romans 16:20 The God of peace will soon crush satan under your feet. The grace of our Jesus be with you.
2 Corinthians 2:11 In order that satan might not outwit us. For we are not unaware of his schemes.
1 Timothy 5:15 Some have in fact already turned away to follow satan.
[i] Charles Darwin, The Origin of Species, pp. 172, 280
[ii] http://wwrn.org/article.php?idd=30275
[iii] Guardian, 2 February 2009, Riazat Butt, "Only 25% of Britons believe Darwin's theory of evolution"


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Nature?! It's in my hair!!


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text:
Drug policy timeline
Global drug policy
UK drug policy
Local reforms
Models of regulation
Anyone's Child
Misuse of Drugs Act at 50
A fair, healthy Scotland cannot exist with the highest drug-related death rates in Europe, and outbreaks of HIV infection within its most vulnerable communities. The UK and Scottish Governments should work together to:
Treat drugs as a health not a criminal justice issue, using evidence-based interventions, tailored to the local situation. Doing so could replicate the dramatic falls in drug-related harms seen in Portugal and Switzerland.
Fully fund treatment, including OST, with wrap-around care to build social assets and psychological resilience.
Decriminalise people who use drugs, reducing stigma and releasing resources to expand harm reduction interventions including Supervised Drug Consumption Rooms.
Explore options for the regulation of some currently prohibited drugs.
Devolve powers under the Misuse of Drugs Act to Scotland either permanently or through temporary special powers, such as by declaring a National Health Emergency, unless the UK Government makes this unnecessary by ending the current enforcement-led approach across the UK.
Developing effective responses to drug-related health harms requires a public health approach. This means identifying the nature and scope of the problem, understanding the structural drivers that shape risk and vulnerability, and tailoring interventions to target risk and protective factors. As a result of taking this approach to legal drug policy, Scotland has a strong record of leading the way on innovative reforms - including banning smoking in enclosed public places before the rest of the UK, and introducing Minimum Unit Pricing for alcohol against considerable resistance. Similarly, Scotland has taken a public health approach to crime, and violence in particular, that is drawing attention from the rest of the UK and beyond.1
Scotland now needs to extend an innovative, health-led approach to illegal drug policy.
Health harms from drug use in Scotland - a country in crisis
England, Wales and Northern Ireland have seen near record levels of drug related deaths for five years in a row.2,3 Around a third of all drug deaths in Europe occur in the UK.4
But Scotland's record drug-related death rates are around two and a half times higher than the UK as a whole.5 On average, between 2013 and 2017, 140 deaths per million population were linked to drug use.6 The 2017 figure (934 deaths), was 170 deaths per million, more than double the 455 who died in 2007.7
Increased drug death rates are often blamed on an aging drug-using population. But other European countries have the same demographics, and problems with deprivation and austerity, yet Scotland has the highest drug-related death rate in Europe.8 According to the European Monitoring Centre on Drugs and Drug Addiction (EMCDDA), drug-related death rates for 15-64 year-olds in Scotland were 175 per million in 2015, followed by Estonia (132 deaths per million), Sweden (88 deaths per million), and the UK as a whole (70 deaths per million).9 Since then, Scotland's death rate in this age group has risen substantially to 260 per million in 2017.10
By comparison, Portugal's rate was 3.86 deaths per million - just 27 people from a population almost twice the size of Scotland's.11 Although there are differences in the way drug-related deaths are registered, counted and defined in different countries, Scotland's drug-related death rate remains 40-60 times that of Portugal on the above figures.
Data comparing the first six months of 2018 with 2017 suggest Scotland's crisis is getting worse. For example, Ayrshire drug deaths increased by 119%, Forth Valley 93% rise, Edinburgh 45%, and Glasgow a 41% rise, from 95 to 134.12
NHS Scotland drug-related hospital admissions data also underline the problem:13
According to the National AIDS Trust, the mortality rate for men with HIV was more than four times higher if they injected drugs.14 In Glasgow, there were 121 new HIV infections 2014-17 among people who inject drugs, a tenfold rise in infection rates, and this outbreak is not under control.15
The relationship between poverty, deprivation and problem drug use
Problematic drug use is not the inevitable consequence of initiation. The United Nations Office on Drugs and Crime (UNODC) estimates that around 11% of people who take illegal drugs globally suffer from drug use disorders.16 However, there is a well-evidenced link between problematic or high risk behaviours and risk factors including deprivation, inequality, parental neglect, emotional, physical or sexual abuse, histories of being in care, school exclusion, mental health problems, and unemployment, divorce or bereavement.17
In the most recent available data, approximately half of hospital patients with general acute or psychiatric stays in relation to drug misuse lived in the 20% most deprived areas in Scotland,18 which also saw half - 474 - of Scotland's drug-related deaths in 2017.19
Punitive 'tough on drugs' politics, and criminalisation of people who use drugs
The effects of drug policy need to be considered in the context of conditions surrounding health, welfare, mental health and social services, as well as the inequality, deprivation, and youth alienation that drives problematic use.
Current drug policy rests on two core assumptions: that supply-side enforcement can prevent or significantly reduce drug use, and that criminalisation of people who use drugs is an effective deterrent. Neither stands up to scrutiny.
In 2003 the Prime Minister's Strategy Unit estimated that removing organised criminals from the drug trade would require consistent seizure rates of 60-80%.20 In Scotland estimated heroin seizures were around just 1% of the supply 2000-06.21 Seizures are an affordable cost of business, far less than legal tax rates or product losses (supermarkets waste 2% of food, fresh fish retailers 5% of products).22
In a high-profit market, criminal entrepreneurs always find ways to meet demand. The UK Government's evaluation of its 2010-16 Drug Strategy acknowledges this, stating that 'some enforcement activities can contribute to the disruption of drug markets...but the effects tend to be short-lived. Activity solely to remove drugs from the market, for example, drug seizures, has little impact on availability [...] illicit drug markets are resilient and can quickly adapt to even significant drug and asset seizures.'23 In March 2019, the UN System Coordination Task Team of the UN Chief Executive Board (representing the directors of all 31 UN agencies, and chaired by the Secretary General) concluded that; 'The assumption that tougher law enforcement results in higher drug prices and therefore lowers the availability of drugs in the market is not supported by the empirical evidence.'24
The same is true for user-level deterrence. In 2006 the Science and Technology Select Committee concluded: 'We have found no solid evidence to support the existence of a deterrent effect'.25 The Government said it 'accepts that there is an absence of conclusive evidence'.26 In 2014 the Home Office compared approaches around the world, concluding there was no 'obvious relationship between the toughness of a country's enforcement against drug possession, and levels of drug use in that country'.27 The UK Drugs Strategy evaluation also noted 'a lack of robust evidence as to whether capture and punishment serves as a deterrent for drug use'.28 This confirmed research by the Advisory Council on the Misuse of Drugs,29 the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA),30 and the World Health Organization, which found 'countries with stringent user-level illegal drug policies did not have lower levels of use than countries with liberal ones'.31
Criminalisation of people who use drugs does, however, create and exacerbate health harms. As the Royal Society for Public Health stated:
Criminalisation [of people who use drugs] leads directly to long-term health and wellbeing harm, including greater exposure to drugs in prison, severing of family relationships, and barriers to education and employment. This harm falls disproportionately on disadvantaged ethnic and socio-economic groups – who are far more likely to be charged for drug possession despite similar levels of use – exacerbating existing health inequalities...criminalisation fails to address underlying substance misuse issues and discourages those with an addiction from coming forward for treatment.32
The UK Government's evaluation of its last Drug Strategy also accepts that:
There are potential unintended consequences of enforcement activity such as violence related to drug markets and the negative impact of involvement with the criminal justice system ...including unemployment and harm to families – parental imprisonment is a risk factor for child offending, mental health problems, drug abuse and unemployment amongst others.33
The Director of the UN Office on Drugs and Crime (UNODC) said that current drug policy creates 'a huge criminal black market' and by diverting funding to enforcement, has starved health care of scarce resources.34
Higher levels of enforcement are associated with hurried and higher-risk injecting over safer forms of administration;35 and displacement to other drugs36,37 leading to the use of novel drugs about which little is known.38
Criminalisation can create political and practical obstacles for health professionals to address health problems - as the so far unsuccessful efforts by the NHS in Scotland to open a Supervised Drug Consumption Facility show.
Trying to educate young people about drug risks, while seeking to arrest and punish them, leads to alienation and stigma, undermining outreach to those in need, as a recent EMCDDA report reiterated.39
Prohibition and unregulated supply
As well as fueling organised and acquisitive crime, criminal drug markets encourage the creation and use of more potent drugs that generate greater profits. Under 1920s US alcohol prohibition, consumption of beer gave way to spirits. Under current prohibition, opium has been replaced by heroin and fentanyl, and cocaine markets have evolved towards crack. The cannabis market is saturated with more potent varieties, and synthetic cannabinoids.
Unlike their legal market equivalents, illegally produced drugs lack health and safety information, and are of unknown (and variable) strength and purity, increasing risk of overdose, infection, and poisoning.40
What could Scotland learn from the approach taken to tackle drug misuse in other countries?
Core to reducing drug-related deaths is getting people with drug problems into treatment, and keeping them there until they have built the social assets and psychological resilience they need. That requires a well funded treatment system with routes in for the most marginalised for whom standard paths don't work, and enhanced harm reduction measures that keep people alive until they can engage fully. An ideological focus on abstinence as the sole legitimate outcome of treatment, or stigmatisation through criminalisation, will push those in need away from help and drive up drug deaths. While many public services have borne cuts, underfunding treatment services is a false economy, creating much greater downstream costs.
Financial and political obstacles to innovative, cost-effective, harm-reduction interventions need to be removed. Transform has been closely involved in a number of these measures.
Decriminalise people who use drugs
The United Nations Chief Executives Board for Coordination - representing all 31 UN agencies - has called on member states to 'promote alternatives to conviction and punishment ...including the decriminalization of drug possession for personal use'.41 Decriminalisation is supported by the Lancet42, the British Medical Journal43, the Royal Society for Public Health44, Royal College of Physicians, and British Medical Association. Decriminalisation of some or all drugs is now established policy in more than 25 countries.45 The Global Commission on Drug Policy has developed useful guidance on best practice.46
Since decriminalising possession and use of drugs in 2001, Portugal has seen problematic use, drug-related deaths and HIV infections fall significantly.47 Decriminalisation was the 'critical enabler' that released additional funding for treatment and allowed a more integrated health-based approach. The UK Government should enable Scotland to pursue Portugal's de jure decriminalisation approach as a matter of urgency.
Source: Portugal Country Report 2018 http://www.emcdda.europa.eu/countries/drug-reports/2018/portugal_en and Drug Related Deaths in Scotland, NRS Scotland 2018 https://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/deaths/drug-related-deaths-in-scotland
UK Diversion Schemes
While de jure decriminalisation of drugs is not currently within the gift of the Scottish Government, some of the benefits can be delivered through diversion schemes that Police Scotland, working with the Scottish Government, the Lord Advocate and the procurators fiscal could implement. Currently in Scotland, there is some useful diversion from courts, and Recorded Police Warnings for cannabis possession, but this is not enough. A number of UK police forces including Thames Valley (TVP), Avon and Somerset, and Durham have introduced schemes to divert people caught in possession of any drug for their own use (or in some cases for minor supply, or cultivation of cannabis offences) away from the criminal justice system This number is set to grow rapidly, with interest from police across Britain, and the Home Office and Ministry of Justice.
Diversion can guide people to an assessment, drug education courses, support or treatment, without harming life chances with a criminal record.48 This can be post-arrest, involving deferred prosecution ( Durham's Checkpoint Scheme) or pre-arrest (Avon and Somerset, TVP). Evidence from the UK and globally shows diversion can:
Prevent crime by reducing reoffending
Significantly reduce the financial and resource burden on police forces
Improve the physical and mental health of those diverted and engagement with treatment
Improve the social and employment circumstances of those diverted.
Expand Heroin Assisted Treatment (HAT)49
We welcome that Glasgow is set to open a HAT clinic. But we would like to see this approach expanded to the 10% of the heroin using population for whom other treatment does not work, as in Switzerland, where HAT played a key role in reducing overdose deaths, HIV infections, use of illicit heroin, acquisitive crime, street dealing, and street drug litter, while being cost-effective. HAT was introduced in Switzerland in 1994, along with Supervised Drug Consumption Rooms, as part of a shift to a more health based approach following the failure of a criminal justice crack down to prevent large rises in drug related deaths, and other harms.50,51
UK HAT trials found acquisitive crimes per user fell by two-thirds - around 13,000 fewer crimes per year by the 40 people on the trial.52 Swiss research suggests the 10-15% of people eligible for HAT were using 30-60% of all illegal heroin.52 Taking this group out of the criminal market reduced Organised Crime Group income (for comparison 4% heaviest drinkers in the UK provide 23% of alcohol industry revenue).54 Prior to joining the HAT programme, many participants had been small-scale heroin dealers to fund their own use. Swiss police data showed an 80% fall in the number of small scale heroin dealing offences committed by HAT participants after 24 months. The programme disrupted the function of the heroin market and reduced initiation new users.55
Sources: Addiction Monitoring in Switzerland, Federal Office of Public Health http://www.suchtmonitoring.ch/fr/3/7.html?opioides-mortalite
Drug Related Deaths in Scotland, NRS 2018 https://www.nrscotland.gov.uk/statistics-and-data/statistics/statistics-by-theme/vital-events/deaths/drug-related-deaths-in-scotland
Introduce Drug Safety Testing56
Contamination and variable strength are key drivers of drug-related fatalities. Drug safety testing services allow people to know what they have bought. This reduces the risk of overdose or poisoning, and provides an opportunity to target health advice and monitor drug content and trends.57 Where exceptionally risky drugs are found, medical services can be alerted and public warnings issued.58 Such services have been running in a number of European countries for over 20 years.
After a number of informal UK projects in festivals and city centres since 201659, the Home Office recently licensed a pilot drug safety testing facility in Weston-Super-Mare, delivered by the national treatment provider Addaction. This pilot service was also accessed by people who use heroin.
Supervised Drug Consumption Rooms (DCRs)
DCRs, which engage hard to reach populations in treatment, have prevented overdose deaths and HIV infections across the world, and are recommended by the ACMD.60 However, they remain blocked by the UK Home Office.61 This is despite the Home Office acknowledging the public health benefits, for example in this letter to Glasgow City Council, which had unanimously asked permission to open one:62
The Government's own report, Drugs: International Comparators (2014), acknowledges that there is some evidence for the effectiveness of drug consumption rooms in addressing the problems of public nuisance associated with open drug scenes, and in reducing health risks for drug users. The Government's Advisory Council on the Misuse of Drugs (ACMD) has also provided additional evidence based on studies of the effectiveness of facilities in Vancouver and Sydney, noting that they reduce injecting risk behaviours and overdose fatalities. The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) too finds that drug consumption facilities have the ability to reach and maintain contact with high-risk drug users who are not ready or willing to quit drug use.63 Home Office Drug Legislation Team, 2018
The Home Office claim that DCRs would be too difficult to police was subsequently addressed in a letter to the Home Office minister Victoria Atkins, from three Police and Crime Commissioners who had visited operational DCRs. They assured her UK police have the requisite knowledge and skills to manage any issues arising from a DCR, as they do with existing harm reduction measures.64
The UK Government's current main argument for opposing DCRs is that by allowing illegal drug use, they support the illegal drug market. But the reverse is true. Without a DCR, people will still buy the same quantity of drugs - but often use them alone. Indeed, DCRs can reduce the size of the illegal drugs market, as they provide an opportunity to encourage people into treatment - which will mean they will use less heroin or crack. According to the EMCDDA:
There is no evidence to suggest that the availability of safer injecting facilities increases drug use or frequency of injecting. These services facilitate rather than delay treatment entry and do not result in higher rates of local drug-related crime.65
The UK and Scottish Governments should explore options for regulation of drugs production and supply
Handing the drugs market to criminals through prohibition is a key driver of health and social harms. Legally regulating drug markets is now a reality. Beyond the HAT model, multiple jurisdictions are exploring or implementing regulated markets for cannabis, including Uruguay, Canada, Mexico, the Netherlands, New Zealand and 11 US states. Coca is now regulated in Bolivia, and legal regulation of NPS has been considered in New Zealand. Transform has produced a range of proposals and case studies for responsible regulation, and advised many of the countries where this has taken place.66 We note that in 2002, and again in 2012 the Home Affairs Select Committee recommended:
[T]hat the [UK] Government initiates a discussion within the Commission on Narcotic Drugs of alternative ways—including the possibility of legalisation and regulation—to tackle the global drugs dilemma67
Would further devolution of powers enable the Scottish Government more effectively address drugs misuse in Scotland and tailor their approach to Scotland's needs?
Calling for a Health Emergency to be declared
Scottish politicians have rightly described drug-related deaths as a health emergency. However, formally declaring a Health Emergency, and authorising accompanying emergency powers, is not a devolved power. Chapter 6 of Preparing Scotland states: 'The decision to use, or not use, emergency powers, is a matter for the UK Government.' But the powers could be used if a situation threatens 'serious damage to human welfare in the UK, a devolved territory or English region'. And "...the decisive factor will be whether existing powers that could be used to deal with it are insufficient or ineffective.'68
The Scottish Government does not have the power to open supervised drug consumption rooms, or deliver de jure decriminalisation of people who use drugs. But that power could be granted if the UK Government declared a Health Emergency at Scotland's request and created the relevant emergency regulations as part of a set of measures to address drug deaths.
The UK Government should legislate in the normal way as it would be preferable for all areas across the UK to benefit from both decriminalisation and DCRs. But allowing Scotland to pilot DCRs, and decriminalisation under emergency powers, could avoid directly affecting the legal situation in other parts of the UK.
The UK and Scottish Governments should work together to re-centre drug policy towards evidence-based public health and harm reduction approaches, and away from failed punitive enforcement, repressive approaches and a 'war on drugs' ideology.
Responsibility for UK drug policy should move from the Home Office to the Department of Health to help ensure the UK has a joined up, health-led approach.
The UK Government should bring forward UK-wide de jure decriminalisation of small scale non-violent drug offences including possession for personal use, and minor supply or cultivation of cannabis offences. Alternatively, it should devolve the powers needed for Scotland to do so either permanently, or on a pilot basis, for example through special powers after declaring a National Health Emergency in Scotland.
Pending decriminalisation of people who use drugs, the Scottish Government, UK Home Office and Department of Health should work with police forces to develop best practice guidelines for diversion schemes to maximise the public health and crime reduction benefits.
The UK Government should devolve decision-making over opening supervised drug consumption rooms (DCRs) to local areas - including Scotland - as it has done for drug safety testing. This would allow the opening of pilots, with a view to amending the Misuse of Drugs Act 1971 if evaluation demonstrates efficacy.
The UK Government should share its expertise and knowledge, and encourage the Scottish Government to roll-out out drug safety testing, including in city centres for people who use heroin.
The UK Government and Scottish Government should play a leadership role in bringing together stakeholders, and should provide seed-funding for national upscaling of HAT to meet need. Long-term sustainable funding should be delivered through local cost-sharing between public services and businesses that are shown to benefit financially. All funding should be additional to existing resources for drug treatment services.
UK Government should work with devolved administrations to establish an independent expert cross-party parliamentary commission of inquiry to explore options for, and make recommendations on, the legal regulation of currently illegal drugs.
House of Commons Library (2018), 'Public Health Model to reduce youth violence' http://researchbriefings.files...
ONS (2018) Deaths related to drug poisoning in England and Wales: 2017 registrations https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsrelatedtodrugpoisoninginenglandandwales/2017registrations
In 2017 there were 2503 illegal drug related deaths in England and Wales, ONS (2018). Deaths related to drug poisoning in England and Wales: 2017 registrations, p. 3 https://www.ons.gov.uk/peoplepopulationandcommunity/birthsdeathsandmarriages/deaths/bulletins/deathsrelatedtodrugpoisoninginenglandandwales/2017registrations ; 934 drug-related deaths in Scotland in 2017, NRS (3 July 2018)https://www.nrscotland.gov.uk/files/statistics/drug-related-deaths/17/drug-related-deaths-17-pub.pdf ; and 136 in Northern Ireland, NI Statistics and Research Agency Drug-related deaths 2007-17, (March 2019) https://www.nisra.gov.uk/publications/drug-related-and-drug-misuse-deaths-2007-2017
EMCDDA (2018), European Drug Report Trends and Developments, p.75 http://www.emcdda.europa.eu/sy...
National Records Scotland (2018). Drug-related deaths in Scotland, 2018, p.6 https://www.nrscotland.gov.uk/files/statistics/drug-related-deaths/17/drug-related-deaths-17-pub.pdf
National Records Scotland (2018). Drug-related deaths in Scotland, 2018, p. 56 https://www.nrscotland.gov.uk/files/statistics/drug-related-deaths/17/drug-related-deaths-17-pub.pdf
EMCDDA (2018), European Drug Report Trends and Developments, p.75 http://www.emcdda.europa.eu/system/files/publications/8585/20181816_TDAT18001ENN_PDF.pdf
NRS Scotland: "The resulting drug-induced death rate (aged 15-64) for Scotland is 175 per million population. This appears to be higher than for any of the countries shown in the EMCDDA table. The next highest rates are for Estonia (132 per million) and Sweden (88 per million)" https://www.nrscotland.gov.uk/files//statistics/drug-related-deaths/17/drug-related-deaths-17-pub.pdf#page=6
National Records Scotland (2018). Drug-related deaths in Scotland, 2018, p. 56 https://www.nrscotland.gov.uk/files/statistics/drug-related-deaths/17/drug-related-deaths-17-pub.pdf NB using the EMCDDA definitions of drug related death this number would be slightly lower.
EMCDDA (2018). Portugal: Country Drug Report 2018. http://www.emcdda.europa.eu/publications/country-drug-reports/2018/portugal_enhttp://www.emcdda.europa.eu/countries/drug-reports/2018/portugal/drug-harms_en
Turriff, C (2018) 'Holyrood told to act as drug death rate soars'. The Times https://www.thetimes.co.uk/article/holyrood-told-to-act-as-drug-death-rate-soars-swqkcpdcw
NHS Scotland Information Service Division (2017) Drug-Related Hospital Statistics Scotland 2016/17 p3.https://www.isdscotland.org/Health-Topics/Drugs-and-Alcohol-Misuse/Publications/2017-09-26/2017-09-26-DRHS-Report.pdf
National AIDS Trust (2019). 'Drug related deaths in England https://www.nat.org.uk/sites/default/files/publications/drug_related_deaths_in_england.pdf
Rise in HIV infections in people who inject drugs - update 2018 https://www.nhsggc.org.uk/your-health/public-health/public-health-protection-unit-phpu/bloodborne-virus/hiv/rise-in-hiv-infections-in-people-who-inject-drugs-update-2018/#
United Nations Office on Drugs and Crime (2018). World drugs report – executive summary, p.7
ACMD, 2018, 'What are the risk factors that make people susceptible to substance misuse problems and harms?' https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/761123/Vulnerability_and_Drug_Use_Report_04_Dec_.pdf; ACMD, 2006, 'Pathways to Problems: Hazardous use of tobacco, alcohol and other drugs by young people in the UK and its implications for policy' https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/119053/Pathwaystoproblems.pdf; ACMD 1998 'Drug Misuse and the Environment' - not currently available online, although the summary is available here: https://www.drugwise.org.uk/wp-content/uploads/ACMD-environment.pdf
NHS Scotland Information Service Division (2017) Drug-Related Hospital Statistics Scotland 2016/17 p4.https://www.isdscotland.org/He...
Iain McPhee, Barry Sheridan, Steve O'Rawe, (2019) "Time to look beyond ageing as a factor? Alternative explanations for the continuing rise in drug related deaths in Scotland", Drugs and Alcohol Today, Vol. 19 Issue: 2, pp.78, https://doi.org/10.1108/DAT-06...
PM Strategy Unit (2003). Drugs Report Phase one – Understanding the issues, p. 73 https://webarchive.nationalarchives.gov.uk/+/http:/www.cabinetoffice.gov.uk/media/cabinetoffice/strategy/assets/drugs_report.pdf
McKeganey, N. et al. (2009). Heroin seizures and heroin use in Scotland. Journal of Substance Use 14.3-4, pp. 240-249 https://www.tandfonline.com/doi/abs/10.1080/14659890902960706?scroll=top&needAccess=true&journalCode=ijsu20
Steven Butts, head of corporate responsibility for Morrisons, evidence to Environment, Food and Rural Affairs Committee, Jan 2017 http://data.parliament.uk/writtenevidence/committeeevidence.svc/evidencedocument/environment-food-and-rural-affairscommittee/food-waste/oral/45673.pdf; WRAP (2011). Resource Maps for Fish across Retail & Wholesale Supply Chains http://www.wrap.org.uk/sites/files/wrap/Resource%20Maps%20for%20Fish%20across%20Retail%20and%20Wholesale%20Supply%20Chains.pdf
HM Government (2017). An evaluation of the Government's Drug Strategy 2010, p.101 https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/628100/Drug_Strategy_Evaluation.PDF
UN system coordination Task Team on the Implementation of the UN System Common Position on drug-related matters (2019)What we have learned over the last ten years; A summary of knowledge acquired and produced by the UN system on drug-related matters https://www.unodc.org/documents/commissions/CND/2019/Contributions/UN_Entities/What_we_have_learned_over_the_last_ten_years_-_14_March_2019_-_w_signature.pdf
House of Commons Science and Technology Committee (2006). Drug classification: making a hash of it?' Fifth Report of Session 2005–06, p.36 https://publications.parliament.uk/pa/cm200506/cmselect/cmsctech/1031/1031.pdf
HM Government (2006). The Government reply to the fifth report from the house of Commons Science and technology Committee Session 2005-06 HC 1031 'Drug classification: making a hash of it?'', p.18 https://www.gov.uk/government/publications/drug-classification-making-a-hash-of-it
Home Office (2011). Drugs: International Comparators, p.51 https://www.gov.uk/government/publications/drugs-international-comparators
HM Government (2017). An evaluation of the Government's Drug Strategy 2010, p.101 https://assets.publishing.serv...
Advisory Council on the Misuse of Drugs (2016). 2016 Drug Strategy: ACMD comments. Available at: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/627980/ACMD_Drug_Strategy_Response__2016__1_Feb_2016.pdf
EMCDDA (2011). Looking for a relationship between penalties and cannabis use - EMCDDA Annual Report, p.45 http://www.emcdda.europa.eu/online/annual-report/2011/boxes/p45
Degenhardt L. et al. (2008) 'Toward a Global View of Alcohol, Tobacco, Cannabis, and Cocaine Use: Findings from the WHO World Mental Health Surveys', PLoS Medicine. www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.0050141
RSPH statement summarising its report 'Taking a new line on drugs' Royal Society for Public Health, supported by the Faculty for Public Health, 2016 https://www.rsph.org.uk/about-...
HM Government (2017). 'An evaluation of the Government's Drug Strategy 2010.' Available at: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/628100/Drug_Strategy_Evaluation.PDF
United Nations Office on Drugs and Crime (2008). 'Making drug control 'fit for purpose': building on the UNGASS decade'. Available at:http://www.unodc.org/documents/commissions/CND-Session51/CND-UNGASS-CRPs/ECN72008CRP17.pdf
Rhodes, T. (20050. The social structural production of HIV risk among injecting drug users. Social Science and Medicine, 61.5, pp. 1026-44
Boyce, N. (2011). Health warnings for people who use heroin. The Lancet, 377:9761, pp. 193-4
Measham, F. et al. (2010). Tweaking, bombing, dabbing and stockpiling: the emergence of mephedrone and the perversity of prohibition. Drugs and Alcohol Today 10.1
Advisory Council on the Misuse of Drugs (2011). Consideration of the Novel Psychoactive Substances ("Legal Highs")' http://www.homeoffice.gov.uk/p... acmdnps2011?view=Binary
EMCDDA (2019) Technical report: drug prevention - exploring a systems perspective. http://www.emcdda.europa.eu/system/files/publications/10403/EMCDDA%20Technical%20report_Drug%20prevention%20systems.pdf
Jones, L. et al. (2011). A summary of the health harms of drugs. NationalTreatment Agency, p. 11. http://www.nta.nhs.uk/uploads/healthharmsfinal-v1.pdf; Cole, C. et al. (2010) Cut: A Guide to the Adulterants, Bulking agents and other Contaminants found in Illegal Drugs. http://www.cph.org.uk/showPubl...
United Nations (2019), 'United Nations Chief Executives Board for Coordination - second regular session of 2018', p. 14. Available at https://www.unsceb.org/CEBPubl...
The Lancet (2016) 'Reforming international drug policy'https://www.thelancet.com/jour...
BMJ (2018) 'Drugs should be legalised, regulated, and taxed' https://www.bmj.com/content/36...
RSPH (2018) 'Royal College of Physicians backs RSPH calls on drug reform' https://www.rsph.org.uk/about-...
Eastwood N, Fox E & Rosmarin A (2016), 'A Quiet Revolution: Drug Decriminalisation Across the Globe' https://www.release.org.uk/pub...
Global Commission on Drugs Policy (2016), 'Advancing Drug Policy Reform: a new approach to decriminalization' http://www.globalcommissionond...
Royal Society for Public Health (2016). 'Taking a new line on drugs', p. 21
Existing schemes include Durham, Avon and Somerset, and Thames Valley
Transform (2018). Heroin Assisted Treatment (HAT) - saving lives, improving health, reducing crime. Available at: https://transformdrugs.org/wp-...
Transform (2017), Heroin Assisted treatment (HAT): Saving lives, Improving Lives, Reducing Crime https://transformdrugs.org/product/heroin-assisted-treatment-hat-saving-lives-improving-health-reducing-crime/
OSF (2020), 'From the Mountaintops: What the World Can Learn from Drug Policy Change in Switzerland'https://www.opensocietyfoundat...
The ~40 people on HAT committed 1731 crimes in the 30 days prior to entering the UK HAT (RIOTT) trial treatment. After 6 months, this fell to 547 crimes (a reduction of over 2/3rds or 1,184 crimes per month). Kings Health Partners and Action on Addiction (2009). 'Untreatable or just hard to treat? Results of the Randomised Injectable Opioid Treatment Trial (RIOTT)', p.3 http://fileserver.idpc.net/library/Untreatable%20or%20just%20hard%20to%20treat.pdf
Killias, M. and Aebi, M. (2000) 'The impact of heroin prescription on heroin markets in Switzerland', Crime Prevention Studies, vol. 11, pp. 83-99.
Aveek Bhattacharya et al, (2018) How dependent is the alcohol industry on heavy drinking in England? https://onlinelibrary.wiley.com/doi/full/10.1111/add.14386
Transform (2018). Drug safety testing: saving lives, increasing awareness. Available at: https://transformdrugs.org/wp-...
F.C. Measham, 'Drug safety testing, disposals and dealing in an English field: Exploring the operational and behavioural outcomes of the UK's first onsite 'drug checking' service' International Journal of Drug Policy, Available online 9 December 2018https://www.sciencedirect.com/science/article/abs/pii/S0955395918302755
EMCDDA (2017), 'Drug checking as a harm reduction tool for recreational drug users: opportunities and challenges' p.4http://www.emcdda.europa.eu/system/files/attachments/6339/EuropeanResponsesGuide2017_BackgroundPaper-Drug-checking-harm-reduction_0.pdf
See: https://wearetheloop.org/
ACMD (2016) 'Reducing opioid-related deaths in the UK' https://www.gov.uk/government/...
Transform (2017). 'Drug consumption rooms: saving lives, making communities safer',
Safe drug consumption rooms – Motion approved. (2018) http://www.glasgow.gov.uk/Councillorsandcommittees/viewSelectedDocument.asp?c=P62AFQDN2U0G0GUTT1
Letter to Glasgow City Council from Home Office Drugs Legislation Team (2018) Reported on Glasgow City Council website https://www.glasgow.gov.uk/ind... Copy of letter available on request.
Letter from PCCs David Jamieson, Ron Hogg and Arfon Jones to the Home Office (2018) STATEMENT ON 'REDUCING OPIOID-RELATED DEATHS IN THE UK REPORT – FURTHER RESPONSE REGARDING DRUG CONSUMPTION ROOMS' available on request
European Monitoring Centre on Drugs and Drug Addiction, 'Drug consumption rooms: an overview of provision and evidence' http://www.emcdda.europa.eu/publications/pods/drug-consumption-rooms_en
See: https://transformdrugs.org/publications/
See: https://publications.parliament.uk/pa/cm200102/cmselect/cmhaff/318/31815.htm and https://publications.parliament.uk/pa/cm201213/cmselect/cmhaff/184/18413.htm
Ready Scotland (2016), 'Preparing Scotland: Scottish Guidance on Resilience, Philosophy, Principles, Structures and Regulatory Duties' https://www.readyscotland.org/media/1166/preparing-scotland-philosophy-principles-structures-and-regulatory-duties-20-july-2016.pdf
'Diversion', 'Decriminalisation', or 'Tough Consequences': What's in a name?
Misrepresentations of cannabis regulation are damaging
Right to Recovery Bill: A Response
9-10 King Street
BS1 4EQ


text:
General Installation Guide for Parallel Louvain Community Detection method
=====================================================================================

Pre-Requisites
--------------

* We have tested our system with Linux – Ubuntu/Debian variant (although all windows equivalent s/w are available and may be used)

* MPI runtime (preferable Open MPI 1.6 or higher)

 * On a single machine (Make sure no MPI )

sudo apt-get -y install build-essential g++ python-dev autotools-dev libicu-dev libbz2-dev

sudo apt-get install libcr-dev mpich2 mpich2-doc

 * Set up a MPI Cluster (see http://techtinkering.com/2009/12/02/setting-up-a-beowulf-cluster-using-open-mpi-on-linux/)

* Metis Graph Partitioner

sudo apt-get -y install metis

Compile
--------

Once the prerequisite are installed, download the code from the git repository mentioned earlier.

Following is the strucutrue of the source code

parallel-louvain-modularity/

├── conf

├── data

│   └── graphs

├── opt

│   └── python

└── src

    ├── benchmark

    ├── parallel   //parallel louvain algorithm

    ├── ref

    ├── sequential //Sequential louvain algorithm

    └── tools

go to src/parallel directory and run $make to complile the source code

Execution
---------

You need to have a graph in metis format and edge list format.
Assume following are sample graphs

*4elt.txt - graph in edge list format.

*4elt.graph - graph in metis graph format.

* First the given graph (in METIS format) needs to be portioned into desired number of partitions. For example

gpmetis ./4elt.graph 2

This will create a partition file 4elt.graph.part.2

Psuedo Distributed (single node):

Then you need to convert the graph using the conversion tool to binery format. This will create .bin and .remote file for each partition. .bin file contains the local graph for each partition while .remote files contain mappings of cross partition edges.

Example:

./convert -i 4elt.txt -o 4elt -p 4elt.graph.part.2 -n 2

General format is :

./convert -i <graph in edge list format> -o <output graph name> -p <partition file> -n <number of partitions>

This will create .bin files with format 4elt_<partition id>.bin and .remote files with format 4elt_<partition id>.remote.

Use the Open MPI's mpi-run command to start the algorithm using the desired number of processors (NOTE: This should be equal to the number of partitions)

example:

mpirun -np 2 ./community 4elt -r 4elt -l 2 -v > level2.txt

the general format is:

mpirun -np <number of processors> ./community <graph name> -r <graph name> -l <output level> -v verbose > output file

*Number of Processors: This is equal to the number of partitions

*Graph Name: Name of the output graph given in conversion tool

*output level: displays the graph of level k rather than the hierachical structure.
	if k=-1 then displays the hierarchical structure rather than the graph at a given level

*verbose : verbose mode: gives computation time, information about the hierarchy and modularity.

On MPI Cluster
--------------

Run the same command as before from the Cluster's head node.

Data Format
------------

We use the standard usnweighted METIS graph data format for input graphs. See http://glaros.dtc.umn.edu/gkhome/fetch/sw/metis/manual.pdf for details.

To summarize, the metis format of the following

1. First line indicating the number of vertices and edges

2. All subsequent lines contain the data per vertex and its (undirected) edges in following format

e1 e2 …

For example: The following undirected graph is represented using:

Metis File:

4 5 //4: num vertices, 5: num edges

2 3 4  // e1 w1 e2 w2 e3 w3 for vertex 1

1 3 4

1 2

1 2

Edge List file is just a standered undirected list of edges. Each line corresponds to an edge in metis formated graph. Same vertex ids must be used in both files.

Following is the edge list for above graph

1 2

1 3

1 4

2 1

2 3

2 4

3 1

3 2

4 1

4 2

redpajama_set_name: RedPajamaGithub


Spiders probably evolved about 400 million years ago from thick-waisted arachnid ancestors that were not long emerged from life in water. The first definite spiders, thin-waisted arachnids with abdominal segmentation and silk producing spinnerets, are known from fossils like Attercopus fimbriungus. This spider lived 380 million years ago during the Devonian Period, more than 150 million years before the dinosaurs.
Most of the early segmented fossil spiders belonged to the Mesothelae, a group of primitive spiders with the spinnerets placed underneath the middle of the abdomen (rather than at the end as in 'modern' spiders). They were probably ground dwelling predators, living in the giant clubmoss and fern forests of the mid-late Palaeozoic, where they were presumably predators of other primitive arthropods (like cockroaches, giant silverfish, slaters and millipedes). Silk may have been used simply as a protective covering for the eggs, a lining for a retreat hole, and later perhaps for simple ground sheet web and trapdoor construction.
As plant and insect life diversified so also did the spider's use of silk. Spiders with spinnerets at the end of the abdomen (Opisthothelae) appeared more than 250 million years ago, presumably promoting the development of more elaborate sheet and maze webs for prey capture both on ground and foliage, as well as the development of the safety dragline.
By the Jurassic Period (191 - 136 million years ago), when dinosaurs roamed the earth, the sophisticated aerial webs of the orb weaving spiders had developed to trap the rapidly diversifying hordes of flying insects. Similarly, the diversification of hunting spiders in litter, bark and foliage niches would have progressed in response to new prey-capture and habitat opportunities.
Despite this the spider fossil record is relatively poor. During the Tertiary Period the rich record of amber spider fossils - complete spiders trapped in clear, sticky, tree resins - show us that a spider fauna basically similar to that of the present day existed more than 30 million years ago.
Amazingly, segmented mesothelid spiders have survived in eastern Asia (China to Indonesia) from late Palaeozoic times to the present day. These large, impressive spiders live in soil burrows with trapdoors in forested areas and caves.Segmented spiders are very similar to their ancestors and have virtually remained unchanged . They are not found in Australia.
A 300 million year old, half metre long, fossil arachnid, Megarachne servinei, was originally described as a spider, but is now thought more likely to represent another type of spider-like ancient arachnid. Its unique features include the enormous size, massive shovel-like jaws and ribbed, shield-like covering over the abdomen. An arachnid of this size must have fed on large prey like cockroaches and giant millipedes. But why did this massive predator need such an impressively armoured body - were there even bigger arachnid predators about?
Red-headed Mouse Spiders have a smooth, glossy carapace and their head area is high, steep and broad with very large, bulbous jaws.


text:
You are here: Home › Baahubali (బాహుబలి) 2015
Baahubali (బాహుబలి) 2015
Published on May 16, 2016 in Cinema
Banner Arka Media Works
Director S. S. Rajamouli
Writer K. V. Vijayendra Prasad
Producer Shobu Yarlagadda, Prasad Devineni
Music Director M. M. Keeravani
Cinematography Senthil Kumar
Film Editing Venkateswara Rao Kotagiri
Art Director Manu Jagadh, Rahul Panchang
Playback Singers Surya Yamini, Geetha Madhuri, Ramya Behara, Deepu, M.M.Keeravaani, Mounima, Karthik, Damini, Mohana Bhogaraju, Revanth, Adithya
Baahubali / Sivudu Prabhas
Bhallaladeva Rana Daggubati
Devasena Anushka Shetty
Avanthika Tamannaah Bhatia
Sivagami Ramya Krishnan
Bijjaladeva Nasser
Aslaam Khan Sudeep
Kattappa Satyaraj
Swamiji Tanikella Bharani
Gabriela Bertante
Nora Fatehi
Kalakeya War Lord Prabhakar
Spirit Seller (Cameo) S.S. Rajamouli
Sanga Rohini
Subbaraya Sarma
Bhadra Adivi Sesh
Subbaraju
Hero friend Venkat Vadisetti
Bhallaladeva's Soldier Rakesh Varre
Scarlett Mellish Wilson
In the ancient Kingdom of Mahishmati in India, Sivagami, the queen (Ramya Krishnan), emerges from a cave adjoining a big waterfall, carrying a baby. She kills the soldiers pursuing her and sacrifices herself to save the baby. Local villagers spot the queen carrying the baby while almost drowning in the river and rescue the infant. The queen drowns after pointing towards the mountain above the waterfall. Sanga (Rohini) and her husband name the infant Shiva and raise him as their own son. They seal the cave fearing that someone may come to take away the child.
Shiva (Prabhas) grows up to be a well-built young man aspiring to hike the mountain and makes many unsuccessful attempts at it. It is revealed that he possesses unnatural strength. He then finds a mask of a girl which falls from the waterfall. Driven to find out the identity of the girl, he climbs the mountain again and succeeds this time.
On top of the waterfall, Shiva discovers that the mask belongs to Avanthika (Tamannaah), a rebellious warrior whose group has indulged in a guerrilla warfare against king Bhallala Deva / Pallvalathevan (Rana Daggubati) of the Mahishmati Kingdom. The group intends to rescue their former queen Devasena (Anushka Shetty) who has been chained in the kingdom for the past 25 years. Avanthika is given the opportunity to rescue the queen.
Avanthika falls in love with Shiva after she finds out that he has climbed the waterfall for her. Shiva pledges to help her in her mission and sneaks into Mahishmati to rescue Devasena. Shiva rescues her and flees along with her but is chased down by the king's Royal slave Kattappa (Sathyaraj), known for his great warrior abilities. After Shiva beheads Bhadra (Adivi Sesh), Bhalla Deva's son, Kattappa drops his weapons on realising that Shiva is Mahendra Baahubali, the son of late king Amarendra Baahubali.
A flashback reveals Amarendra Bahubali's past. Amarendra's mother died while giving him birth, while his father had died much before that. Sivagami takes charge of running the kingdom with Kattapa's assistance until a new king is elected. Amarendra Bahubali and Bhallala Deva are brought up together, trained in all areas including arts, science, disguise, politics and warfare, but both of them have different approaches towards kingship. Amarendra Baahubali is liberal to everyone but Bhallala Deva is violent and achieves his goals with any means possible.
When a war is forced upon Mahishmati by the Kalakeyas, Sivagami promises that the new king will be the one who beheads the Kalakeya king and orders that the war resources be distributed equally between the two cousins. Bijjala Deva (Nassar), Bhalla Deva's father, uses his cunningness to make sure Bhalladeva gets the maximum war fare. When it seems that Mahishmati would end up being defeated, Amarendra inspires his soldiers to fight to the death and they end up crushing the enemy. Despite Bhalla Deva being the one to kill the Kalakeya king, Sivagami announces Amarendra Baahubali as the new emperor because of his nobility and leadership in the war.
After the flashback, when asked about Amarendra's current whereabouts, a tearful Katappa reveals that the King is dead, and that Katappa himself is the one responsible for his dead.
Release Date 10-July-2015
Budget ₹120 crore (US$18 million)
Revenue est.₹600 crore (US$89 million)
Academy of Science Fiction, Fantasy & Horror Films, USA (2016):
Saturn Award (Nominated):
Best Fantasy Film
Best Supporting Actress - Tamannaah Bhatia
Best Music - M.M. Keeravani
Best Production Design - Sabu Cyril
Best Costume Design - Rama Rajamouli, Prashanti Tipirineni
Asian Film Awards (2016):
Nominated:
Best Visual Effects - Srinivas Mohan
IBNLive Movie Awards (2016):
Best Actor South - Prabhas
National Film Awards, India (2016):
Golden Lotus Award (Won):
Best Feature Film - S.S. Rajamouli (director), Shobu Yarlagadda (producer), Arka Mediaworks (production company)
Anushka Shetty Tamannaah Bhatia Ramya Krishnan telugu cinema, Baahubali 2015 tollywood movie mp3 songs in online, Baahubali telugu audios, Golden Lotus Award won movie, Karthik songs playlist, M.M. Keeravani musical hits, Prabhas Rana Daggubati hit film, S. S. Rajamouli block baster movie in telugu
Jodhaa Akbar (जोधा अक्बर) 2008
Baahubali (बाहुबली) 2015


In contemporary Boston, Dracula gatecrashes a Satanic ritual and makes off with the intended sacrifice, Delores. Overcome with love for her, he's unable to drink her blood and instead settles down with her and fathers a child, Janus. But Dracula's enemies are massing against him—a team of vampire hunters, including the wheelchair-bound Hans Harker, crossbow wielding and new recruit Frank Drake, a descendant of Dracula, are closing in. And Dracula has been stripped of his vampire powers by Satan and he desperately needs another vampire to restore his powers so that he can both see off his pursuers and avenge the death of Janus at the hands of vengeful Satanists.
Nuclear testing has resulted in the abrupt evolution of the Fumoon, a tiny but highly intelligent humanoid race on a small island, who are detected by Dr. Yamadano. Except for a few witnesses including the detective Shinsaku Ban, and the young men Rock and Kenichi and Kenichi's sister Pichi (Pinoko), no one believes him. The Fumoon are kidnapping animals from around the world to bring with them as they use their space ships to evacuate the earth, because they know Earth is shortly to be destroyed by an enveloping cloud of black gas created by a stellar explosion. The Fumoon intend to abandon mankind, but one Fumoon, Rokoko, who becomes good friends with Kenichi, tries to help Dr. Yamadano and the others to develop a space ship to allow a few humans to escape, with the help of Dr. Ochanomizu and Dr. Frankenstein.


Whimsy Whimsical is a collection of woodland inspired gifts and paper goods which aims at bringing a touch of whimsy into your daily life.
Proudly printed in Malaysia using environmental friendly paper stock with soy ink. Each notepad includes 50 sheets and measures 12.7cm x 17.7cm (5"W x 7"H).


A software developer from Swansea is in the running for a top business award, after displaying his innovation and drive to the judges during the shortlisting process.
After meeting Andrew Downie, judges at the British Small Business Champions 2007 said, "This young business should continue to grow offering competitive products in a difficult market", of his company NetBop Technologies.
Twenty-five year old Andrew is a regional finalist in the Young Entrepreneur category. He founded NetBop Technologies five years ago, offering web development and ecommerce solutions to business. The company has flourished in a short time, recently expanding with new staff and moving into larger premises in Swansea.
Unlike many web developers Downie has developed his own suite of products, including Bopspam, which blocks junk e-mails; and BopControl, a simple way for businesses to update their websites.
Downie is also prepared to take on the big boys and win. Last year he won the right to market his junk email filter, using the word 'spam', despite strong objections by the makers of the American meat product, SPAM.
No stranger to award ceremonies, Downie has collected a series of accolades over the years for his websites and products, including Web User Magazine's Gold Award twice. The company was named in Wales Hot 100 last year and Downie himself has been identified as one of the rising stars of Welsh business.


I am an amateur photographer specializing in landscapes, cityscapes, and street photography.
Currently, I am a content creator with Sky City Church. My responsibilities include photography, graphic design, website maintenance, social media, and video editing.


text:
WATCH DOCS (Poland)
Helsinki Foundation for Human Rights - Zgoda 11
00-018 Warsaw (Mazowsze)
Poland Telephone: 0048225564473
Email: festival@watchdocs.pl
Web: www.watchdocs.pl
Deadline: 05/Aug/2013
Films pertaining to broadly conceived human rights issues may be submitted to the festival.
The festival presents mainly documentary films and films from the fringes of this genre.
Other film genres (feature, animated, educational etc.) may be presented only outside of the competition section of the festival repertoire.
There are no limitations as to year or country of production or running time of the films presented out of competition.
In the competition section of the festival, only documentary films produced after 1st of January 2012 will be screened.
Films previously screened as part of the festival shall not be accepted for the competition section.


text:
Sardar Patel
SARDAR PATEL NEWS
Patel birth anniversary: Priyanka's tweet on BJP 'trying to appropriate Patel' irks ruling party
Union minister Smriti Irani who was in her constituency, Amethi, to take part in the 'Run for Unity' event targeted the Congress general secretary.
Delhi: Leaders' photos dot Ramlila Maidan ahead of BJP meet
More than 2,000 workers have been tasked with looking after the arrangements and logistics for the event. Party sources said that over 3,000 hotel rooms have been booked for leaders coming from different parts of the country.
Ahmedabad airport was named after Sardar Vallabhbhai Patel in my rule: Shankersinh Vaghela
Shankersinh Vaghela was with the BJP until 1996 when he formed the Rashtriya Janata Party and served as the Chief Minister of Gujarat from 1996 to 1997.
Statue of Unity inauguration: A look at world's 6 tallest statues
Statue of Unity Inauguration: The Statue of Unity beats China's 'Spring Temple Buddha' as the world's tallest statue and is said to be twice the height of the Statue of Liberty in the US. Here is a look at the other tallest statues of the world.
'Run for Unity' on Sardar Patel's 143rd birth anniversary
The Run for Unity is organised to encourage Indians to run in tribute to Sardar Vallabhbhai Patel.
Uniting, he stands
Narendra Modi writes: Sardar Patel worked with astonishing speed to dismantle the legacy of imperialism and create the geography of unity with the spirit of nationalism.
From Plate to Plough: Sardar's unfinished task
The real tribute to Patel would be to carry out large-scale structural reforms in agri-markets to ensure that a higher percentage of the consumer's rupee goes to farmers.
By-election to civic bodies: 'People rejected Cong as it spreads caste hatred'
Jitu Vaghani on Saturday congratulated BJP party workers of the Sabarkantha district unit, at a meeting held in Himmatnagar, for winning six of the 11 seats in six nagarpalikas where by-elections were held on Tuesday
With Sardar Patel, Gandhi, police stations get makeover
Elaborating on the plans for the Lodhi Colony police station, a police officer said that besides the two portraits, a contingent of Delhi Police officers will also be painted on the walls.
PM Modi, others pay tribute to Sardar Patel on his 68th death anniversary
It was Patel who unified the country and helped in bringing together disjointed territories after the country's partition. He was instrumental in the merger of more than 560 princely states with the Union of India without any bloodshed.
SARDAR PATEL PHOTOS
Iron Man 2: The making of world's tallest statue of Sardar Patel
The world's tallest statue dedicated to Sardar Vallabhbhai Patel, stands at about 120-130 metres height — minus the head and shoulders, which will together add up to the final 182-metre (597-feet) plan.
Preparations for R-Day in full swing
25 tableaux would participate in the parade, with 16 of them belonging to states and the union territories.
SARDAR PATEL VIDEOS
What PM Modi said about Sardar Patel when he unveiled the statue.
Prime Minister Narendra Modi recounted the work done by Sardar Vallabhbhai Patel in his speech as he paid his tribute.
The World's Tallest Statue - Statue of Unity is now open
The Statue of Unity will be inaugurated by Prime Minister Narendra Modi on October 31, 2018. Here are some interesting facts about world's tallest statue located at the Sardar Sarovar Dam on Narmada river in Gujarat.
Why Are We Talking About Hardik Patel: Beyond The News
Tripura Congress: 'Have identified, warned leaders having secret links with BJP'
Two crore books showcased during 43rd Chennai Book Fair
Quentin Tarantino's Once Upon a Time in Hollywood to re-release in India on Feb 14
Lucknow: Magsaysay winner booked for 'indecent remarks' against Veer Savarkar
Shoaib Malik might continue after T20 World Cup if body permits